baber/WOPTO huggingface dataset:
Patent EP-0921125-A1 (EP)
Inventor: ADAM GEO
IPC: A61K31/00
Filed: 1998-11-27
Abstract: The present invention relates to compounds of the general formula
 
wherein
     R 1     is hydrogen, lower alkyl, halogen, lower alkoxy, trifluoromethyl,
lower alkyl-phenyl or (C 5 - 7 )-cycloalkyl;   R 2     is hydrogen, lower alkyl, phenyl or lower alkyl-phenyl;   R 3     is hydrogen, lower alkyl, benzyl, lower alkyl-phenyl, lower alkyl-diphenyl,
triazinyl, cyanomethyl, lower alkyl-piperidinyl, lower
alkyl-naphthyl, (C 5 - 7 )-cycloalkyl, lower alkyl-(C 5 - 7 )-cycloalkyl,
lower alkyl-pyridinyl, lower alkyl-morpholinyl, lower alkyl-dioxolanyl,
lower alkyl-oxazolyl or lower alkyl-2-oxo-oxazolidinyl
and wherein the ring systems may be substituted by additional
lower alkyl, lower alkoxy, trifluoromethyl or phenyl, or
-(CH 2 ) n C(O)O-lower alkyl, -(CH 2 ) n C(O)NH 2 ,
-(CH 2 ) n C(O)N(lower alkyl) 2 , -(CH 2 ) n OH or -(CH 2 ) n C(O)NHCH 2 C 6 H 5 ;   R 4     is hydrogen, lower alkyl or nitrilo;   A   is a ring system, consisting of
   (a) (C 5 - 15 )-cycloalkyl, which may be in addition to R 4 optionally substituted
by lower alkyl, trifluoromethyl, phenyl, (C 5 - 7 )-cycloalkyl, spiro-undecan-alkyl
or by 2-norbornyl, or is one of the following groups 
 
dodecahydro-acenaphthylen-1yl (e), bicyclo[6.2.0]dec-9-yl (f) and
bicyclononan-9-yl (g);       
and wherein
   R 5  and R 6     are hydrogen, lower alkyl or taken together and with the carbon
atoms to which they are attached form a phenyl ring;   R 7     is hydrogen or lower alkyl;   
the dotted line represents an optional bond and
   n   is 1 to 4;   
and to pharmaceutically acceptable acid addition salts thereof.
     Compounds of the present invention are agonists and/or antagonists of
the Orphanin FQ (OFQ) receptor. Consequently they will be useful in the
treatment of memory and attention deficits, psychiatric, neurological and
physiological disorders, especially, but not limited to, amelioration of
symptoms of anxiety and stress disorders, depression, trauma, memory loss
due to Alzheimer's disease or other dementias, epilepsy and convulsions, acute
and/or chronic pain conditions, symptoms of addictive drug withdrawal,
control of water balance, Na +  excretion, arterial blood pressure disorders and
metabolic disorders such as obesity.
Patent EP-0885557-A1 (EP)
Inventor: ALVAREZ BERENGLIER ANTONIO
IPC: A01K1/015
Filed: 1998-06-19
Abstract: A new composition which is absorbent and inhibitive of
the formation of bad smells in absorbent hygienic litter
for animals that comprises a carrier and a molecular
complex is described. The carrier is a porous, granular,
solid, clayish, mineral substrate with a high specific
surface, with a high liquid absorption capacity. The
molecular complex is a mixture of natural and/or synthetic
organic compounds, some identical to natural ones, with
properties inhibitive of bad smells, caused by the products
of bacterial degradation of cat urine, by means of specific
reactions of neutralization thereof. The molecular complex
is basically retained inside the structure of the particles
of the carrier, in such a way that the inhibitive activity
thereof is regulated and strengthened by the
physicochemical properties of the carrier. 
     Preferably, the molecular complex is present in the
composition in a conclentration of 0.02 to 2% of the total
weight thereof.
Patent EP-1004785-A1 (EP)
Inventor: PROMPER CHRISTOPHE
IPC: F16D1/10
Filed: 1998-11-24
Abstract: The coaxial shafts (11,25) each comprise an end (10,26) opposite the other which is liable to approach the other by a relative translation along the geometrical rotational axis (15). A compressible metal bellows (50) is located between the shaft ends. The coupling (30) is active when the shafts are brought together and inactive when the shaft ends are separated. The coupling has rotational driving female and male parts (31,40). The female part comprises two hollows (32) the opening (33) of which is turned towards the end of the second shaft. The hollows each have two female sides (34) which are widened towards the opening. The male part comprises two teeth (41) the top (42) is turned towards the end of the first shaft. The teeth each comprise two male sides (43) which penetrate the hollows when the two shafts are brought together.
Patent EP-0894869-A1 (EP)
Inventor: MIYAMOTO YOSHIKO
IPC: G01N27/327
Filed: 1998-07-22
Abstract: A biosensor is disclosed which facilitates high
accuracy quantitation of a substrate by best eliminating
adverse effects of red blood cell existing in blood
together with the substrate. The biosensor comprises an
electrode system including a working electrode and a
counter electrode formed on an electrically insulating
base plate, and a reaction layer containing at least an
oxidoreductase and an electron acceptor, wherein the
electron acceptor is a sodium salt.
Patent EP-0911788-A1 (EP)
Inventor: NEPOTE ALAIN
IPC: G09F3/12
Filed: 1998-10-22
Abstract: The tag (1) includes a fastening with male and female components. The male component (2) comprises a projection (7) with a pointed tip and a number of notches (4) formed between truncated conical surfaces on a stem (5).
Patent EP-1028857-A1 (EP)
Inventor: DRAGNEA MIHAI
IPC: B44C5/04
Filed: 1998-02-25
Abstract: The invention relates to an imitation stone for decorating building structures which is comprised of three layers. One layer is discontinuous of the surface having different colorings and a thickness of 0-5 mm. A second layer is a continuous intermediate layer having only one color and a thickness of 2-5 mm. A third layer is a base and resistance inner layer having a thickness of 3-10 mm. The shape and coloring of the stone imitates those of natural stone. The first two layers have 28-48 wt. % polyester resin with reinforcers, or polyvinyl chloride or polystyrene optionally with the addition of cross-linking agents, 50-70 wt. % quartz powder and 2-10 wt. % pigments. The inner layer has 100 wt. % polyurethane foam with reinforcers or 20-35 wt. % fiber glass and 65-80 wt. % polyester resin with reinforcers. The imitation stone is produced in a rigid or flexible structure in which the mixture for the surface layer, the intermediate layer, and the base layer is successively applied by spraying or with a brush. The layers cure and combine with one another. The product is manually pulled out of the interior of the structure and the entire external surface is sandblasted. An additional method is comprised of applying a continuous layer of the curing base mixture on the inner surface of the structure. The mixture is manually pulled out and a continuous layer of the mixture having only one color is applied on the entire external surface of the layer. The mixture hardens and discontinuous mixtures for the surface layer having different colorings are applied over said continuous layer. The mixture hardens and the entire external surface is sandblasted.
Patent EP-1007553-A1 (EP)
Title: Zonula occludens toxin receptors
Inventor: FASANO ALESSIO
IPC: G01N33/15
Filed: 1998-02-18
Abstract: Receptors for the zonula occludens toxin of Vibrio cholera, as well as methods involving the use of the same are disclosed.
Patent EP-0998227-A1 (EP)
Inventor: FOSTER THOMAS L
IPC: A61B17/00
Filed: 1998-02-24
Abstract: A minimally invasive, medical device 10 for removing stones, calculus or the like from the renal or biliary systems includes a reversibly collapsible basket 12 and an elongated member 14 for delivering the basket 12 to the location of the stones, calculus or the like. The basket 12 is tipless and atraumatic in use, and includes at least one superelastic wire loop 20 and at least one superelastic wire leg 26, the wire leg 26 preferably being incorporated into a second superelastic wire loop 24. The basket 12 is preferably formed from a shape memory material such as a suitably annealed nitinol alloy. The basket 12 includes means 28 for restricting relative movement of the first wire loop 20 and the wire leg 26 or the second wire loop 24, continuously formed with the first loop 20 and the leg 26 or the second loop 24. The movement restricting means 28 is preferably formed as a first smaller loop 30 in the first loop 20 interlocked with a second smaller loop 32 in the leg 26 or in the second loop 24. The elongated member 14 is preferably a flexible sheath or the like 34 of a length suitable for introduction of the basket 12 into the major and minor renal calyxes. The first loop 20 and the leg 26 or the second loop 24 have longitudinally extending portions 40 and 46 slidably received in the flexible sheath or the like 34. In this way the basket 12 can be retracted into or extended from the elongated member 14. The device 10 is particularly advantageous in being kink-free during use and in possessing a useful diameter significantly smaller than other eggwhip-type retrieval devices.
Patent EP-1017310-A1 (EP)
Title: Procede et dispositif permettant l'evaluation de la pression arterielle pulmonaire bloquee entre deux battements de coeur
Inventor: DE BOISBLANC B P
IPC: A61M25/00
Filed: 1998-02-11
Abstract: La présente invention concerne un dispositif permettant l'évaluation de la pression (10) artérielle bloquée, dans lequel on utilise un appareil (13) de mesure de la pression sanguine de l'artère pulmonaire non occluse pour évaluer directement la pression artérielle pulmonaire bloquée. Un réseau (14) neuromimétique est formé sur la base des données obtenues grâce à l'occlusion. Par la suite, les coefficients ainsi obtenus sont utilisés pour actionner l'élément d'évaluation de la pression artérielle bloquée. Un cathéter (15) flottant est utilisé pour transduire la forme d'onde de la pression qui est ensuite introduite dans l'ordinateur (11) de traitement par l'intermédiaire d'un tableau (12) d'acquisition des données analogique-numérique. Les données sont prétraitées par l'ordinateur (11) en vue de fournir au réseau neuromimétique onze échantillons de données relatives à la pression sanguine et, simultanément, onze échantillons des premiers dérivés des données relatives à la pression sanguine ainsi qu'une indication concernant la durée du battement du coeur. Ensuite, le réseau (14) neuromimétique formé délivre directement l'évaluation de la pression artérielle pulmonaire.
Patent EP-0954689-A1 (EP)
Inventor: SANS MARIANO
IPC: F02M25/07
Filed: 1998-01-14
Abstract: Dispositif de commande d'un moteur à combustion interne (41) à injection directe et allumage commandé, adapté pour éviter les variations brutales de couple lors d'une commutation de mode de combustion de mélange homogène à stratifié et inversement, comportant des moyens de détermination (0) d'une valeur de consigne (TQE-SP) d'un couple de transmission en fonction de la position (PV) d'une pédale d'accélérateur (11), des moyens de calcul (2) de la valeur d'au moins une commande d'au moins un moyen de réglage (40, 401, 402, 403) du moteur à partir de la valeur de consigne du couple de transmission, lesdits moyens comprenant: un premier modèle inverse (21) du moteur dans son mode de combustion en mélange homogène; un deuxième modèle inverse (22) du moteur dans son mode de combustion en mélange stratifié; des moyens de correction (5) adaptés pour corriger la valeur de consigne du couple de transmission en fonction du mode de combustion du moteur par une correction de couple (TQE-COR) extraite d'une table de correction (51) en fonction d'au moins une variable représentative de la charge du moteur.
Patent EP-0983587-A1 (EP)
Inventor: BOSSEMEYER ROBERT WESLEY JR
IPC: G10L17/00
Filed: 1998-05-12
Abstract: L'invention porte sur un procédé de vérification du locuteur qui consiste à: 1) générer une table de codage (42) dans laquelle on enregistre un certain nombre de locuteurs en associant à chacun d'eux un certain nombre d'énonciations d'entraînement; 2) recueillir un certain nombre d'énonciations d'essai (44) d'un locuteur; 3) comparer (46) chacune des énonciations d'essai avec chacune des énonciations d'entraînement associées audit locuteur pour former un certain nombre de décisions correspondant chacune avec une énonciation d'essai; 4) pondérer chacune des décisions (48) pour former un certain nombre de décisions pondérées; et 5) combiner (50) la série de décisions pondérées pour former une décision de vérification (52).
Patent EP-0918887-A1 (EP)
Inventor: BIERMAN BENJAMIN
IPC: C30B25/12
Filed: 1998-05-12
Abstract: An apparatus to isolate a rotating frame in a processing chamber, comprising: a support cylinder rotatably extending from the rotating frame; and a co-rotating edge ring extension extending from the support cylinder to at least one of substantially thermally, optically and mechanically isolate the region above the co-rotating edge ring extension from the region below the co-rotating edge ring extension.
Patent EP-1068033-A1 (EP)
Title: Procede permettant de realiser une connexion etanche aux fluides entre un tube et une partie en forme de plaque
Inventor: MORLEY EDWARD
IPC: B21D39/06
Filed: 1998-03-31
Abstract: L'invention concerne un procédé permettant de réaliser une connexion étanche aux fluides entre un tube et une partie en forme de plaque. Ce procédé consiste à pratiquer dans l'élément en forme de plaque un trou (4) qui corresponde sensiblement à la section du tube, à insérer dans le trou (4) une extrémité du tube, de façon que l'extrémité du tube s'étende partiellement au-delà de la surface de la partie en forme de plaque, à insérer dans le tube un mandrin (10) comportant une première partie (11) présentant une section qui correspond sensiblement à la section intérieure du tube, une seconde partie (13) présentant une section augmentée et une partie de transition (12) située entre ces deux parties. Ce procédé consiste ensuite à maintenir le tube dans sa position insérée tout en exerçant une pression à l'aide du mandrin sur l'extrémité insérée du tube, à chauffer le mandrin jusqu'à ce qu'il atteigne une température au moins suffisante pour ramollir la matière du tube puis à maintenir cette situation pendant une durée suffisante pour déformer l'extrémité du tube sur les parties en forme de plaque.
Patent EP-0984944-A1 (EP)
Inventor: BAUMANN ERNST
IPC: A01N43/56
Filed: 1998-05-05
Abstract: Die Erfindung betrifft 4-(3-Alkenyl-benzoyl)-pyrazole der Formel (I), in der die Variablen folgende Bedeutung haben: R1, R2 Wasserstoff, Nitro, Halogen, Cyano, Rhodano, Alkyl, Halogenalkyl, Alkoxyalkyl, Alkenyl, Alkinyl, -OR?6, -OCOR7¿, -OSO¿2R?7, -SH, -S(O)¿n?R?8, -SO¿2OR6, -SO2NR?6R9, -NR9SO¿2R7 oder -NR?9COR7; R3¿ Wasserstoff, Halogen, Alkyl, Halogenalkyl, Alkoxy, Alkenyl, Alkinyl; R4, R5 Wasserstoff, Nitro, Halogen, Cyano, Rhodano, Alkyl, Halogenalkyl, Cycloalkyl, Alkenyl, Cycloalkenyl, Alkinyl, Alkylthio, Halogenalkoxy, -COR10, -CO2R?10, -COSR10, -CONR10R11, -C(R12)=NR13¿, -PO(OR?10) (OR11¿); gegebenenfalls substituiertes Alkyl, Heterocyclyl, Heterocyclylalkyl, Phenyl, Phenylalkyl, Hetaryl oder Hetarylalkyl; oder R?4 und R5¿ bilden gemeinsam eine Alkandiyl-Kette, die substituiert und/oder durch ein Heteroatom unterbrochen sein kann; Q ein substituiertes in 4-Stellung verknüpftes Pyrazol; sowie deren landwirtschaftlih brauchbaren Salze; Verfahren zur Herstellung der Verbindungen er Formel (I); Mittel, welche diese enthalten; sowie die Verwendung dieser Derivate oder diese enthaltenden Mittel zur Bekämpfung unerwünschter Pflanzen.
Patent EP-1085812-A1 (EP)
Inventor: JONES PETER WYN
IPC: A01N65/00
Filed: 1998-05-20
Abstract: A hatch-inactive stimulating agent obtainable from plants of the Solanaceae family has been found to be capable of stimulating hatching factor-induced hatch of potato cyst nematode. This stimulating agent can be used together with one or more hatching factor(s) in a hatching factor preparation, which is free of any hatching inhibitors, for the control of potato cyst nematode. The preparation is capable of achieving a maximum kill of 70-80 % of a viable potato cyst nematode egg population when the preparation is applied to a locus at a concentration of 10-20 g per hectare.
Patent EP-0986390-A1 (EP)
Inventor: GENNE PHILIPPE
IPC: A61P9/06
Filed: 1998-06-08
Abstract: The invention relates to pharmaceutical compositions containing cinchonine dihydrochloride as active ingredient with a purity of at least 95%. The invention also relates to a process for preparing cinchonine dihydrochloride from cinchonine and the use of pharmaceutical compositions containing cinchonine dihydrochloride for treating multiple drug resistance.
Patent EP-0986727-A1 (EP)
Title: Heat exchanger made from a mixture of silicon carbide and molybedenum disilicide
Inventor: LORSON HARALD
IPC: F28F21/04
Filed: 1998-05-22
Abstract: The invention relates to a ceramic recuperative high-temperature heat exchanger (1), wherein all components coming into contact with primary (P) and/or secondary (S) media are made of high-temperature resistant material. The high-temperature material consists of a mixture of SiC and MoSi2. The self-defining flow channels (4) and flow areas (5) of the heat exchanger are formed by plates (6), comprising a congruent matrix configuration of truncated recesses (7) with an open bottom. The plates (6) are stacked on top of each other in such a way that the tubular lower end of the covering surface of the recesses (7) of the upper plate (6) rests on the spherical covering surface of the recesses of the plates (6) disposed thereunder, in such a way that the flow channels (4) are formed by the substantially self-aligned recesses (7). The flow area (5) which is formed between the plates (6) is lower in height than the recesses (7). It is penetrated by the covering surfaces of the recesses (7) in the form of columns. The flow areas (5) have inflows and outflows only.
Patent EP-1003558-A1 (EP)
Title: Lipid-polyamide conjugates and compositions for nucleic acid delivery
Inventor: ZUCKERMANN RONALD N
IPC: A61K47/48
Filed: 1998-08-13
Abstract: In accordance with the present invention, there are provided lipid-conjugated polyamide compounds and related compositions and methods thereof. Lipid-conjugated polyamide compounds of the present invention are particularly useful as vehicles for delivering biologically active agents to a target site. In particular, the invention compounds are effective at facilitating the delivery of polynucleotides to cells. The present invention also provides a method for producing stable formulations of polynucleotides complexed with a delivery vehicle.
Patent EP-1011975-A1 (EP)
Inventor: TEMPLE STEPHEN
IPC: B41J2/14
Filed: 1998-09-07
Abstract: A drop-on-demand multi-tone printing apparatus has a series of channels arranged to receive ink from a source. Each channel has a respective ink outlet. Each adjacent pair of the channels is separated by a respective dividing wall, and each dividing wall is movable in response to a respective pulsed electrical signal to apply pressure pulses to the respective pair of the channels, whereby ink can be ejected from the outlets and deposited onto a recording medium. A respective pulsed electrical signal is developed for each channel in dependence upon whether ink is to be ejected from that channel, the signals for adjacent pairs of the channels temporally overlapping each other and not being in phase with each other.
Patent EP-0970697-A1 (EP)
Inventor: OCHI YASUO
IPC: C07D307/93
Filed: 1998-09-16
Abstract: A cervical maturing agent containing a prostaglandin I derivative as the active ingredient. It exerts excellent maturing effect on the
cervical canal without causing any uterine contraction, which makes it useful as a cervical maturing agent.
Patent EP-1019584-A1 (EP)
Inventor: CAMILLERI PAUL ANTHONY
IPC: E02D5/80
Filed: 1998-09-18
Abstract: L'invention concerne un dispositif d'ancrage (10) de pilier à vis. Le dispositif comprend un axe tubulaire (11) doté d'une vis (20) et d'un foret (12) qui s'engage dans le sol au niveau de l'extrémité s'engageant dans le sol. L'ensemble stabilisateur (30) comporte une pluralité d'ailerons (34-37) dirigés radialement depuis des colliers (31-33) montés rotatifs sur l'axe (11). La plaque de montage (51) d'un ensemble colonne d'éclairage (50) peut être fixée sur les ailerons (34-37) par des boulons de fixation (40). L'ensemble stabilisateur (30), grâce aux ailerons (34-37), augmente la résistance de l'axe (11) aux déplacements latéraux, par exemple sous la pression du vent.
Patent EP-1010090-A1 (EP)
Inventor: HAGERSTEN ERIK
IPC: G06F12/10
Filed: 1998-09-04
Abstract: A portion of the global memory of a multiprocessing computer system is allocated to each node, called local memory space. Data from a remote node may be copied to the local memory space of a node such that accesses to the data may be performed locally rather than globally. The global address of the data is translated to a local physical address for the node to which the data is copied. Multiple page of local memory space may be allocated to one entry of a local physical address to global address (LPA2GA) table. When a page is allocated to store shadow pages, an entry in the LPA2GA table associated with that page is marked as unavailable. Accordingly, new translations may not be stored to that entry of the LPA2GA table and other pages associated with that entry may not be allocated to store shadow pages. In a similar manner, multiple pages of the global address space are mapped to an entry in a global address to local physical address(GA2LPA) translation table. When data corresponding to a page within the global address space is stored as a shadow page, the entry associated with the global address is marked as unavailable. Accordingly, other pages associated with that entry of the GA2LPA table may not be stored as shadow pages because the entry is not available. The local copy of the data is not stored and the node must access the data globally.
Patent EP-1129600-A1 (EP)
Inventor: WESTERMANN SOEREN ERIK
IPC: H04R3/04
Filed: 1998-11-09
Abstract: The application relates to an in-situ method to measure and adjust the sound signal presented to the eardrum by means of a hearing aid and a hearing aid employing such a method. The hearing aid comprises microphone (1), signal processing system comprising digital signal processor (2) for transforming the microphone signal into a transformed signal according to a desired transformation function, sensor (4) sensing the sound signal appearing in front of the eardrum and comparator (5). Reference signal processor (6) generates a reference signal based on the output of microphone (1) and representative of the desired sound signal in front of the eardrum. A transfer function between receiver (3) and the output of sensor (4) is established to correct the process in reference signal processor (6). The sound signal in front of the eardrum is sensed, fed back and compared in said comparator (5) with said reference signal. In the case that the difference between the sensed signal and the reference signal is above a predetermined threshold the transformed signal is corrected to adjust said signal in front of the eardrum to the desired sound signal.
Patent EP-1036102-A1 (EP)
Inventor: CALDERARA ISABELLE
IPC: G02C7/04
Filed: 1998-12-03
Abstract: The invention concerns a method for making a transparent polymer material with little tendency to accumulate deposit. The method consists in immersing a transparent polymer matrix in a solution in a solvent for swelling the polymer matrix of a composition comprising a zwitterion polymerizable monomer and an agent for cross-linking the monomer to cause the polymer matrix to swell and become impregnated with the composition, optionally removing the matrix from the solution and hardening the composition impregnated within the matrix, said hardening being carried out in the presence of a polymerization initiator initially present in the matrix or the swelling solution. The invention is useful for making contact lenses and intraocular implants.