baber/WOPTO huggingface dataset:
Patent CA-2728083-A1 (CA)
Inventor: BAO JIAN
IPC: C07D489/02
Filed: 2009-06-16
Abstract: The invention provides processes for the conversion of a 6-keto morphinan to a 6-hydroxy morphinan. In particular, the invention provides a stereoselective process for the conversion of a 6-keto morphinan to a 6-beta-hydroxy morphinan. The reduction is preferably done by formamide sulfinic acid and in the presence of a protein receptor (i.e. a base) which is added in two portions, second portion after one of the reaction components has precipitated in the solution.
Patent CA-2729495-A1 (CA)
Inventor: MARSILJE THOMAS H III
IPC: C07D409/14
Filed: 2009-06-24
Abstract: The invention provides novel pyrimidine derivatives of formula I and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of insulin- like growth factor (IGF-IR) or analplastic lymphoma kinase (ALK).
Patent CA-2731313-A1 (CA)
Inventor: VAN DEN BERG KAREL
IPC: A01J5/017
Filed: 2009-07-27
Abstract: Device for milking an animal, such as a cow, comprising an animal standing area to be occupied by the animal to be milked in a particular milking position and a robot device with a robot arm assembly for applying to and/or removing teat cups from the respective teats of the udder of the animal, wherein the robot arm assembly at a distal end is provided with holding means for the teat cups, wherein the robot arm assembly at a proximal end is suspended from a support so as to extend downwards therefrom and is rotatable with respect thereto about a first centre line which has a vertical direction component, wherein, in use, the first centre line intersects the floor of the animal standing area.
Patent CA-2733347-A1 (CA)
Title: Dispositif de chauffage et/ou de rafraichissement d'un volume de fluide contenu dans une enceinte en particulier d'un volume d'eau contenu dans une piscine et piscine equipee d'un tel dispositif
Inventor: COMPARON JEAN-DANIEL
IPC: F24H1/18
Filed: 2011-03-01
Abstract: La présente invention concerne un dispositif de chauffage et/ou de rafraichissement (1) d'un volume de fluide contenu dans une enceinte délimitée par des parois, en particulier d'un volume d'eau contenu dans une piscine (2), ledit dispositif comprenant au moins un circuit alimenté par des moyens de chauffage et/ou de refroidissement, et agencé pour être disposé le long au moins du fond (21) de ladite enceinte (2), caractérisé en ce que ledit circuit est lié à un support (3, 3', 30) pour former une nappe dont le pourtour et les dimensions sont adaptés à la forme de la surface dudit fond (21), en ce que ledit circuit comporte plusieurs serpentins (11, 12, 13, 14, 15, 16) pourvus chacun d'un orifice d'entrée (110) et d'un orifice de sortie (111) pour un fluide caloporteur communiquant avec un collecteur (4) apte à être relié auxdits moyens de chauffage et/ou de refroidissement, et en ce que lesdits serpentins (11-16) sont montés en parallèle sur ledit collecteur (4) et agencés pour définir plusieurs zones chauffantes adjacentes et réparties sur la surface de ladite nappe.
Patent CA-2733482-A1 (CA)
Inventor: MUHLENKAMP ERIC E
IPC: A47L9/10
Filed: 2011-03-09
Abstract: A floor cleaning apparatus includes a housing having a nozzle assembly and a canister assembly. The nozzle assembly includes a suction inlet. Both a suction generator and a dirt collection assembly are carried on the housing. The dirt collection assembly includes a dirt cup, a shroud concentrically received within the dirt collection chamber defined by the dirt cup and at least one rib projecting from the shroud toward the bottom wall of the dirt cup. The rib is positioned so as to reduce air turbulence in the dirt collection chamber between an airflow guide on the shroud and the bottom wall of the dirt cup.
Patent CA-2734941-A1 (CA)
Title: Grille de stations terrestres de reception et d'enregistrement de donnees satellitaires
Inventor: ANTIKIDIS JEAN-PIERRE
IPC: H04B7/185
Filed: 2009-08-21
Abstract: L'invention concerne un dispositif, dit grille satellitaire, comprenant une pluralité de stations terrestres de réception et d'enregistrement dotées de moyens de mémorisation, chaque station comportant des moyens de réception de données d'observation en provenance d'au moins un satellite en orbite autour de la Terre.  Chaque station est reliée à au moins un réseau numérique et dotée d'au moins un module de gestion adapté pour que les différentes stations coopèrent ensemble afin de permettre un accès partagé transparent permanent auxdites données d'observation en provenance d'au moins un satellite et enregistrées dans les différentes stations, ladite grille satellitaire étant adaptée pour pouvoir être accessible et vue comme une ressource informatique unique à partir de tout point d'accès dudit réseau.
Patent CA-2734970-A1 (CA)
Title: Docking station
Inventor: FRANKE VOLKER
IPC: H04N5/44
Filed: 2009-08-26
Abstract: Docking station for a modular device for digital multimedia reception, in particular for digital tele-vision reception, for the detachable coupling of a device for decoding digital multimedia signals, wherein the dock-ing station comprises a back end interface (480) with a first coupling area (481a) designed for the detachable cou-pling of an external back end assembly group (180), as well as an HDMI input interface (484) designed for the de-tachable coupling of an HDMI output interface of an ex-ternal device for decoding digital multimedia signals (8).
Patent CA-2735843-A1 (CA)
Title: Detecteur de surpression et de talonnage pour amortisseur ou similaire
Inventor: MARTIN PASCAL
IPC: F16F9/32
Filed: 2009-09-01
Abstract: L'invention est relative à un détecteur de surpression et de talonnage, le détecteur comportant un corps creux (11) dans lequel coulisse à étanchéité un piston (14) destiné à être soumis à une pression par l'intermédiaire d'une entrée (12) du corps en communication avec une enceinte dans laquelle règne ladite pression, le piston étant retenu en position à l'encontre de la pression par un moyen de retenue à seuil (21) adapté à libérer le piston lorsque la pression atteint ou dépasse ledit seuil de sorte que le piston soit poussé sous l'effet de la pression vers une position d'indication, et dans lequel le piston est solidaire d'un doigt (27) qui saille de l'entrée du corps pour pouvoir être poussé à l'encontre du moyen de retenue à  seuil.
Patent CA-2736361-A1 (CA)
Inventor: GARCIA-ECHEVERRIA CARLOS
IPC: A61P35/00
Filed: 2009-10-29
Abstract: The invention relates to a pharmaceutical combination which comprises (a) a phosphoinositide 3-kinase inhibitor compound of formula (I) and (b) a mTOR inhibitor for the treatment of a target of raparnycin (mTOR) kinase dependent disease, especially a cancer disease; a pharmaceutical composition comprising such a combination; the use of such a combination for the preparation of a medicament for the treatment of a proliferative disease; a commercial package or product comprising such a combination as a combined preparation for simultaneous, separate or sequential use; and to a method of treatment of a warm- blooded animal, especially a human.
Patent CA-2737469-A1 (CA)
Inventor: RYDLEWICZ RONI
IPC: A44C17/00
Filed: 2008-09-16
Abstract: A decagonal shaped diamond, adapted to display a hearts and arrows pattern when exposed to light comparable to the hearts and arrows pattern in a round diamond. The decagonal shaped diamond should be cut to form ten main crown facets of substantially equal size symmetrically arranged relative to one another surrounding a table facet twenty star facets with two star facets polished on every main crown facet, ten main pavilion facets, an equal number of crown half facets as pavilion half facets and ten main girdle facets with the girdle facets polished at a given angle relative to one another for forming the decagonal shape of the diamond.
Patent CA-2739489-A1 (CA)
Inventor: AMER MOH SAMIR
IPC: A61P9/12
Filed: 2009-10-13
Abstract: Pulmonary arterial hypertension in a mammal can be prevented or treated using combined 5-HT2A and 5-HT2B  receptor antagonist. The antagonists can be present in a single compound or in two separate compounds.
Patent CA-2739713-A1 (CA)
Inventor: CRACIUN LILIANA
IPC: C08J7/04
Filed: 2009-10-21
Abstract: The invention is directed to compositions such as coating, film or adhesive on a surface which comprise a) at least a (meth)acrylate prepolymer, b) an adhesion promoting monomer of formula (I), wherein Q, R1, R2, R4, R5, m and n are defined herein. Further the compositions may be used to enhance adhesion to surfaces, especially metallic surfaces and may include additional optional components such as adhesion promoting photo initiators.
Patent CA-2740197-A1 (CA)
Inventor: AMIN NEELAM S
IPC: C07K7/06
Filed: 2008-10-15
Abstract: The present invention relates to modified variant Bowman Birk Protease Inhibitor proteins (BBPIs) that comprise peptides that bind target proteins, and that are further modified to have greater protease inhibitory activity and/or be produced at greater yields than the unmodified BBPIs. The invention encompasses polynucleotide constructs and expression vectors containing polynucleotide sequences that encode the modified variant BBPIs, the transformed host cells that express and produce the modified variant BBPIs, the modified variant BBPI proteins, the compositions comprising the modified variant BBPIs, and the methods for making and using the modified variant BBPIs in personal care.
Patent CA-2741156-A1 (CA)
Inventor: HARRISON GERALD M
IPC: A47L9/04
Filed: 2011-05-26
Abstract: A floor care apparatus includes a housing having a nozzle assembly and a canister assembly. Both a suction generator and a dirt collection vessel are carried on the housing. An agitator cavity is provided on the nozzle assembly. A rotary agitator is provided in the agitator cavity. The rotary agitator includes an internal space. An agitator drive system is provided in the internal space of the rotary agitator. The agitator drive system includes first and second drive motors that simultaneously drive the agitator.
Patent CA-2741827-A1 (CA)
Inventor: AREVALO RODRIGUEZ ELENA
IPC: B64C9/02
Filed: 2009-10-29
Abstract: Fitting for trimming the horizontal stabilizer of an aircraft made of composite material is taught. The fitting has side walls (2a and 2b) of a torsion box as well as joining elements (3a, 3b) which join the fitting (30) to the frames of the tail fuselage (1) of the aircraft, said side (2a, 2b) being joined together by means of a central element (4) which comprises a first end part (4a) joined to the first side wall (2a) of the fitting (30). A second end part (4b) is joined to the second side wall (2b) of the fitting (30). A central part (4c) joins together said end parts (4a, 4b).  The fitting (30) has end elements (5a, 5b) which are joined to said side walls (2a, 2b) on their outer face. Owing to its greater rigidity in response to side load and vertical load stresses which tend to close the side walls (2a, 2b), the fitting has greater integration and simplicity of load path, for optimum structural behavior in response to the aircraft stresses.
Patent CA-2742244-A1 (CA)
Inventor: COSYNS AUDREY
IPC: C09D143/02
Filed: 2009-11-11
Abstract: An aqueous coating composition for blocking stains and a method of using the coating composition is described.  The coating composition includes an aqueous dispersion of a copolymer that is derived from a single stage emulsion polymeriza-tion of an ethylenically unsaturated nonionic monomer, greater than 0 and less than 1.5% by weight of an ethylenically unsaturat-ed strong acid monomer or salt thereof, and greater than 1.5% and less than 3% by weight of methacrylic acid.
Patent CA-2742585-A1 (CA)
Inventor: WILSON BERNARD R
IPC: G06Q10/00
Filed: 2011-06-09
Abstract: An improved Board of Trade is disclosed. The Board is of the type which promulgates a code of conduct for its members. The improvement comprises including, in the code: standards of conduct regarding activity in space; and;  on the part of any member having control of a rocket for entering space, an obligation to refrain from assisting any person in activity in violation of the standards of conduct regarding activity in space. Also disclosed is a method for promoting the responsible exploitation of space. The method comprises the steps of:  promulgating a code of conduct regarding space activity; including in the code an obligation to sanction persons who violate the code; including in the code an obligation to refrain from assisting any person in activity violating the code; and including in the code an obligation to refrain from assisting any person in space--related activities who refuses to be code bound.
Patent CA-2743116-A1 (CA)
Title: Alpha-conotoxin peptides with a 4/7 motif
Inventor: WATKINS MAREN
IPC: C07K14/435
Filed: 2000-01-28
Abstract: The invention relates to relatively short peptides (termed .alpha.-conotoxins herein), about 10-30 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds.
Patent CA-2746915-A1 (CA)
Inventor: MENZEL JOHANNES
IPC: B01D53/14
Filed: 2009-11-04
Abstract: The invention relates to a method for removing sour gases from raw gases (1).  The removed sour gases are inten-ded to accumulate at a high regeneration pressure. This enables the sour gases to be transported to a storage area with a minimum effort for compression. The raw gas (1) is fed into an absorption column (40) and there purified of the sour gas components pre-sent in the raw gas (1), under increased operational pressure, by means of a physical absorption agent (16). The absorption agent (5) charged with sour gases and useful gases is then fed into a high-pressure stripping column (43), in which a portion of the absorption agent is vaporized, and a stripping vapor is thereby generated. The coabsorbed useful gases are driven out by the strip-ping vapor. The useful gases are drawn off at the head of the high-pressure stripping column (43). The absorption agent present in the head vapors of the high-pressure stripping column (43) is liquefied and fed back into the high-pressure stripping column (43).  The flow of absorption agent (7) departing the base of the high-pressure stripping column (43) is fed into a high-pressure regene-ration column (47), in which the sour gases present in the absorption agent are separated out and drawn off from the head of the high-pressure regeneration column (47) at high pressure. The regenerated absorption agent (10) is drawn off at the base of the high-pressure regeneration column (47) and fed back into the absorption column (40).
Patent CA-2747426-A1 (CA)
Inventor: JING CHARLIE
IPC: E21B49/00
Filed: 2009-12-14
Abstract: Method for using seismic data from earthquakes to address the low frequency lacuna problem in traditional hydrocarbon exploration methods. Seismometers with frequency response down to about 1 Hz are placed over a target subsur-face region in an array with spacing suitable for hy-drocarbon exploration (21). Data are collected over a long (weeks or months) time period (22).    Seg-ments of the data (44) are identified with known events from earthquake catalogs (43). Those data segments are analyzed using techniques such as trav-eltime delay measurements (307) or receiver func-tion calculations (46) and then are combined with one or more other types of geophysical data acquired from the target region, using joint inversion (308-310) in some embodiments of the method, to infer physical features of the subsurface indicative of hydrocarbon potential or lack thereof (26).
Patent CA-2748411-A1 (CA)
Title: Derives de 2-pyridin-2-yl-pyrazol-3(2h)-one, leur preparation et leur application en therapeutique comme activateurs de hif
Inventor: ALTENBURGER JEAN-MICHEL
IPC: A61P9/00
Filed: 2009-12-24
Abstract: L'invention concerne des composés répondant à la formule (I) : R représente un groupe -SO2-NR3R4, un atome d'hydrogène, un atome d'halogène, un groupe -halogéno(C1 -C5)alkyle, un groupe -CO2R5 ou un groupe -SO2-R4; R1 représente un groupe hétérocycloalkyle ne contenant pas d'atome d'azote, un groupe -W-(C3-C6)cycloalkyle, un groupe -W-aryle, un groupe -W-hétéroaryle, un groupe -W-hétérocycloalkyle, un groupe -W-C00R5, un groupe -W-CONR5R6; R2 représente un atome d'hydrogène, un groupe -(C1 -C5)alkyle, un groupe -(C1 -C5)alkylène-0-(C1 - C5)alkyle, un groupe -halogéno(C1 -C5)alkyle, un groupe -W-C00R5, un groupe -W-C(O)NHR5 ou un groupe -W-C(O)-NR5R6; n représente 0, 1 ou 2; W est un groupe - (C1 -C5)alkylène- ou un groupe -(C3-C6)cycloalkylène-; R3 et R4, identiques ou différents, représentent, indépendamment l'un de l'autre, un atome d'hydrogène, un groupe -(C1 -C5)alkyle, un groupe -(C3-C6)cycloalkyle, un groupe -(C1 -C5)alkylène-O-(C1 -C5)alkyle, un aryle, un groupe -CH2-aryle, un hétéroaryle, un hétérocycloalkyle, un groupe -W-OH, un groupe -W-CHOH-CH2OH, un groupe -W-CO2R5,un groupe -W-NR5R6 ou un groupe -W-O-(CH2)n-aryle; ou bien R3 et R4 forment ensemble avec l'atome d'azote qui les porte un groupe hétérocycloalkyle; R5 et R6, identiques ou différents, représentent, indépendamment l'un de l'autre, un atome d'hydrogène, un groupe -(C1 -C5)alkyle ou un groupe (C1 -C5) halogénoalkyle, ainsi que leur procédé de préparation et leurs applications en thérapeutique.
Patent CA-2749554-A1 (CA)
Title: Synthetic chord
Inventor: LONGORIA JAMES
IPC: A61B17/04
Filed: 2010-01-08
Abstract: Synthetic chord devices and methods for using the same for connecting tissues are provided. Aspects of the synthetic chord device include a flexible cord having an attachment element at both a first and a second end, wherein each attachment element includes a piercing member coupled to a securing member that attaches the flexible cord to a first tissue. At least a portion of the flexible cord can be configured to be secured to a second tissue. Aspects of the invention also include sets of the synthetic chord device with pre-measured flexible cords. The devices and methods of the invention find use in a variety of applications, such as in applications in which it is desired to repair a heart valve.
Patent CA-2749819-A1 (CA)
Inventor: DAVIES KENETH
IPC: A61P25/00
Filed: 2010-03-09
Abstract: The present invention relates to a tricyclic heterocyclic derivative according to Formula (I), wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to pharmaceutical compositions comprising said tricyclic heterocyclic derivatives and to their use in therapy, for instance in the treatment or prevention of serotonin mediated disorders, such as obesity.
Patent CA-2750214-A1 (CA)
Inventor: PODPORKIN GEORGY VIKTOROVICH
IPC: H01T4/16
Filed: 2009-01-19
Abstract: A lightning arrester for protecting elements of electrical facilities or a power transmission line comprises an insulating body which is made of a solid dielectric, preferably in the form of a bar, a strip or a cylinder, two main electrodes that are mechanically coupled to the insulating body and two or more intermediate electrodes. The intermediate electrodes, preferably made in the form of bars or cylinders, are arranged between the main electrodes so that said intermediate electrodes are mutually shifted along the longitudinal axis of the insulating body or along a spiral line. Such design makes it possible to form a discharge channel between the adjacent electrodes. Furthermore, said electrodes are located inside the insulating body and are separated from the surface of the body by an insulation layer.  Discharge chambers formed as cavities or through bores opened to the surface of the insulating body are arranged between the pairs of the adjacent electrodes.  Dimensions of the chambers are selected such that a discharge is easily blown out from the chambers to the surface of the insulating body, thereby increasing the efficiency of the discharge current quenching. In the preferred embodiments, the arrester is provided with an additional electrode for reducing a flashover voltage. Various embodiments of a power transmission line using the arrester of the invention are also disclosed.
Patent CA-2751049-A1 (CA)
Inventor: CAMUS MICHEL
IPC: B44F1/10
Filed: 2010-02-03
Abstract: La présente invention concerne un élément de sécurité (1) comportant un substrat au moins partiellement transparent, sur le recto et le verso duquel figurent respectivement et partiellement des premières (3) et des deuxièmes (4) marques sous la forme de métallisations et/ou d'impressions, les premières marques (3) se superposant majoritairement aux deuxièmes marques (4), les premières et deuxièmes marques (3, 4) formant respectivement des premier et deuxième motifs distincts selon leurs faces respectives, le degré de visibilité des deuxièmes marques (4) variant avec l'angle d'observation du recto de l'élément de sécurité (1), l'épaisseur du substrat étant comprise entre 5 et 100 µm.
Patent CA-2752132-A1 (CA)
Inventor: HANSON SVERKER
IPC: C07D473/36
Filed: 2003-04-15
Abstract: There is disclosed the use of a compound of formula (Ia) or (Ib) wherein R1, R2, R3, R4, X and Y  are as defined in the specification, and pharmaceutically acceptable salts thereof, in the manufacture of a medicament, for the treatment or prophylaxis of diseases or conditions in which inhibition of the enzyme myeloperoxidase (MPO) is beneficial. Certain novel compounds of formula (Ia) or (Ib) and pharmaceutically acceptable salts thereof are disclosed, together with processes for their preparation. The compounds of formulae (Ia) and (Ib) are MPO inhibitors and are thereby particularly useful in the treatment or prophylaxis of neuroinflammatory disorders.   (see formula Ia) (see formula Ib)
Patent CA-2753488-A1 (CA)
Inventor: MAHFOUZ MOHAMED RASHWAN
IPC: G16Z99/00
Filed: 2010-02-25
Abstract: The exemplary embodiments of the present disclosure are described and illustrated below to encompass methods and devices for designing patient specific prosthetic cutting jigs and, more specifically, to devices and methods for segmenting bone of the knee and the resulting cutting guides themselves. Moreover, the present disclosure relates to systems and methods for manufacturing customized surgical devices, more specifically, the present disclosure relates to automated systems and methods of arthroplasty cutting guides, systems and methods for image segmentation in generating computer models of knee joint.
Patent CA-2755528-A1 (CA)
Title: Derives de n-[(6-aza-bicyclo[3.2.1]oct-5-yl)-aryl-methyl]-heterobenzamide, leur preparation et leur application en therapeutique
Inventor: ESTENNE-BOUHTOU GENEVIEVE
IPC: A61P25/00
Filed: 2010-03-15
Abstract: Composé de formule générale (I) : dans laquelle : - R représente un atome d'hydrogène ou un groupe choisi parmi les groupes (C1-C6)alkyle ou (C3-C7)-cycloalkyle éventuellement substitué par un ou plusieurs groupes choisis indépendamment l'un de l'autre parmi l'atome d'halogène, les groupes (C3-C7)-cycloalkyle, (C1-C6)alkyle, (C1-C6)alcoxy, hydroxy; - R1 représente un groupe phényle éventuellement substitué par un ou plusieurs substituants choisis indépendamment l'un de l'autre parmi les atomes d'halogène, les groupes (C1- C6)alkyle, (C1-C6)alcoxy, halo-(C1C6)alkyle, hydroxy, halo-(C1-C6)alcoxy, (C1-C6)alkyle-thio, (C1-C6)alkyle-SO, (C1-C6)alkyle-SO2, - R2 représente un ou plusieurs substituants choisis parmi l'atome d'hydrogène, les atomes d'halogène, les groupes halo-(C1-C6)alkyle, (C1-C6)alkyle, (C3-C7)cycloalkyle, (C3-C7)- cycloalkyl-(C1C3)alkyle, phényl, benzyl, (C1-C6)alcoxy, (C1-C6)alkyle-thio, (C1-C6))alkyle-SO, (C1-C6)alkyle-SO2; - Het représente un groupe hétéroaryle; à l'état de base ou de sel d'addition à un acide. Utilisation en thérapeutique et procédé de synthèse.