baber/WOPTO huggingface dataset:
Patent WO-2019168947-A1 (WO)
Title: Protéines bifonctionnelles combinant un blocage des points de contrôle pour une thérapie ciblée
Inventor: YOU JHONG-JHE
IPC: G01N33/574
Filed: 2019-02-27
Abstract: L'invention concerne des protéines bispécifiques qui comprennent une protéine de surface se liant à un domaine de liaison et un domaine d'inhibition de facteur de croissance endothéliale vasculaire (VEGF). Un conjugué anticorps-médicament qui comprend un agent thérapeutique et un anticorps ou un fragment de celui-ci se liant à l'antigène qui se lie à PD-L1 et/ou à un domaine d'inhibition de VEGF est en outre décrit, où l'agent thérapeutique est conjugué par covalence à l'anticorps ou au fragment de celui-ci se liant à l'antigène par l'intermédiaire d'un lieur.
Patent WO-2020190257-A1 (WO)
Inventor: PALMER JACOB
IPC: H01R13/6581
Filed: 2019-03-15
Abstract: A cable enclosure includes a housing defining an opening through which an interior of the housing is accessible. An end plate is releasably secured to the housing to cover the opening such that the interior of the housing is not accessible. The end plate includes a first conductive leg in electrical communication with a first cable within the housing. The end plate also includes a second conductive leg in electrical communication with a second cable within the housing. The end plate further includes a conductive member movable between a first position and a second position. When in the first position, the conductive member is in contact with the first conductive leg and the second conductive leg. When in the second position, the conductive member is not in contact with at least one of the first conductive leg or the second conductive leg.
Patent WO-2019194992-A1 (WO)
Title: System and method extending range of a wireless network
Inventor: SOOD AYUSH
IPC: H04L5/04
Filed: 2019-03-22
Abstract: A system and method are provided for extending range of devices in a legacy wireless network. Generally, the method involves providing in a transmitter of the system a frame having a first field including a number of preamble segments and a second field including a number of data segments. The transmitter in the system is then operated to transmit at least one of the preamble segments with at least a first transmit power, and to transmit the segments of the second field at a second transmit power, wherein the first transmit power is greater than the second transmit power. Other embodiments are also described.
Patent WO-2019199680-A1 (WO)
Title: Dynamic filter
Inventor: LARKIN BRENDAN
IPC: H04B15/00
Filed: 2019-04-08
Abstract: The current invention is intended to render artifacts, which are introduced by changes in coefficients in an FIR filter, inaudible by applying a window to the filtered signal that results in the output of the filter (e.g. FIR filter), in which the coefficients are being changed, supplying little or none of the total output while the output of the filter, in which the coefficients are stable, supplies most or all of the total output.
Patent WO-2019199752-A1 (WO)
Inventor: GOLDBACH JAMES T
IPC: C08F214/20
Filed: 2019-04-09
Abstract: L'invention concerne de nouveaux fluoropolymères fonctionnels linéaires, semi-cristallins qui ont été obtenus par copolymérisation d'un monomère vinylique fluoré et d'un comonomère (méth) acrylique hydrophile portant une fonctionnalité halogène.
Patent WO-2019200397-A1 (WO)
Inventor: CLARKE MICHAEL F
IPC: G01N33/574
Filed: 2019-04-15
Abstract: La présente invention concerne des données montrant que le LEFTY inhibe des voies favorisant la différenciation telles que BMP7/pSMAD5 dans des lignées cellulaires du cancer du sein, en plus et au-delà de son rôle connu d'inhibition de Nodal/pSMAD2. Le LEFTY fait concurrence avec le BMP7 pour se lier à son récepteur de surface cellulaire BMPR2, conduisant à l'inhibition de pSMAD5. L'interaction LEFTY-BMPR2 est dominante sur BMP-BMPR2 dans des cellules tumorigènes, conduisant à un état pSMAD diminué, tandis que dans des cellules non tumorigènes, il existe une interaction LEFTY-BMPR2 minimale, une association BMP7-BMPR2 augmentée et un pSMAD élevé. L'invention décrit des compositions et des procédés pour induire ou inhiber l'expression et/ou l'activité de protéines LEFTY et BMP, qui peuvent être utilisés dans le diagnostic et la thérapie du cancer et d'autres états, et pour favoriser la prolifération de cellules souches.
Patent WO-2019210052-A1 (WO)
Title: Methods and systems for determining the risk of developing ovarian cancer
Inventor: LETOVSKY STANLEY
IPC: G16H10/40
Filed: 2019-04-25
Abstract: The present invention relates to systems and methods for utilizing the measurement of two or more biomarkers to determine a probabilistic assessment for developing ovarian cancer. Particularly, aspects of the present invention are directed to a computer implemented method that includes obtaining, by a computing device, measured levels of two or more biomarkers in a sample obtained from a subject without knowledge of an ovarian mass or tumor in the subject, and determining, by the computing device, a probabilistic assessment of the subject developing ovarian cancer based on the obtained values. The coefficients of the logistic regression models used can take into account a time to diagnosis variable or unspecified omitted factors.
Patent WO-2019210213-A1 (WO)
Inventor: RAWLINGS DAVID J
IPC: C12N15/90
Filed: 2019-04-26
Abstract: La présente invention concerne des compositions d'édition génomique améliorées et des procédés d'édition d'un gène BTK humain. L'invention concerne en outre des cellules dont le génome a été édité pour la prévention, le traitement ou l'amélioration d'au moins un symptôme d'une agammaglobulinémie liée à l'X (XLA).
Patent WO-2019213364-A1 (WO)
Title: Glass angle limiting filters, methods for making the same, and pulse oximeters including the same
Inventor: LEE WOONG-HEE
IPC: C03C4/04
Filed: 2019-05-02
Abstract: Angle limiting filter include a glass substrate including a plurality of non-transparent glass-ceramic regions and a plurality of substantially optically transparent regions in an alternating arrangement. The non-transparent glass-ceramic regions and the substantially optically transparent regions are formed from the same glass composition. A method for forming the angle limiting filter includes irradiating a glass substrate with an ultra-violet radiation source through a patterned photomask to selectively irradiate regions in the glass substrate. The method also includes heating the glass substrate thereby transforming the irradiated regions into non-transparent glass-ceramic regions and forming an alternating arrangement of non-transparent glass-ceramic regions and substantially optically transparent regions in the glass substrate. Electronic devices, including pulse oximeters, including the angle limiting filter are also described.
Patent WO-2019213518-A1 (WO)
Inventor: O'HEERON PETE
IPC: A61K35/33
Filed: 2019-05-03
Abstract: La présente invention concerne, selon des modes de réalisation, des procédés et des compositions permettant de traiter ou de prévenir la douleur chez un individu. Dans des modes de réalisation spécifiques, les procédés et les compositions comprennent des fibroblastes et/ou des dérivés de fibroblastes pour le traitement de tout type de douleur, y compris la douleur dorsale. Dans des aspects particuliers, des exosomes et/ou un lysat et/ou un milieu conditionné provenant des fibroblastes sont administrés à un individu en ayant besoin.
Patent WO-2019222664-A1 (WO)
Title: Systems and methods for cognitive diagnostics in connection with major depressive disorder and response to antidepressants
Inventor: HERZALLAH MOHAMMAD
IPC: G16B5/00
Filed: 2019-05-17
Abstract: A system for diagnosing a mental health condition. The system comprises a smart device and a device including a memory and a processor. The smart device allows a participant to perform a cognitive task and the device receives data collected from the smart device in connection with the cognitive task performed by the participant. The device determines whether the participant has the mental health condition based on the data collected and via a classification algorithm or an artificial intelligence approach. If the participant has the mental health condition, the device determines whether the participant will respond to medication for treating the mental health condition via the classification algorithm or the artificial intelligence approach.
Patent WO-2019226669-A1 (WO)
Title: Identifying treatment options for sclc patients
Inventor: THYPARAMBIL SHEENA P
IPC: G01N33/68
Filed: 2019-05-21
Abstract: Disclosed herein are methods for selecting a suitable anticancer drug for the treatment of a lung tumor to a patient in need thereof by using clinical proteomics. The methods disclosed herein comprise performing proteomic analysis of the tumor to quantify protein expression; and determining whether the anticancer drug is suitable or unsuitable for the treatment of the lung tumor by comparing the protein expression of the tumor with a pre-defined threshold for that protein.
Patent WO-2019226749-A1 (WO)
Title: Box pump system and method of use
Inventor: MUEHLICH CHRISTIAN
IPC: F04B39/10
Filed: 2019-05-22
Abstract: Pump systems and methods are disclosed for removing liquid for hand-portable containers. The pump systems include a moveable piston housed in a main chamber and inlet and outlet valves located at one end of the main chamber, where the inlet and outlet valves open and close in response to movement of the piston.
Patent WO-2019226909-A1 (WO)
Title: Electronic talking stick
Inventor: STRADLEY SUZANNE
IPC: G06F1/16
Filed: 2019-05-23
Abstract: An electronic talking stick system has a hand-held electronic talking stick having a body with an outer casing, a microprocessor executing coded instructions, a data repository, an electronic timer, a display screen, a microphone, a mechanism generating alerts to a user at specific times according to the electronic timer, wireless communication circuitry, and a power supply powering electrical and electronic components, and a smartphone comprising wireless communication circuitry compatible with the wireless communication circuitry of the hand-held electronic talking stick, and a microprocessor executing an application for managing functionality of the hand-held electronic talking stick.
Patent WO-2020242447-A1 (WO)
Inventor: SACHS PETER
IPC: G05D1/00
Filed: 2019-05-24
Abstract: Data associated with a flight, including a flight plan, a vehicle, and/or a pilot is processed via a risk assessment platform to obtain one of more numerical risk values, for example a ground risk value and an air risk value. Based on the processed data, a matrix of risk assessment decisions is generated containing risk related information (such as risk remediation information). Accordingly, based on a consistent set of risk relation information, a predictable and repeatable flight decision (such as a decision whether to fly, or an adjustment to a flight route) can be made. In some instances, the data to be processed is quantitative data collected from one or more third party systems, such as sensor data or geospatial data. The risk assessment platform includes toolkits or services to be used in the processing and transformation of this data to reach a risk assessment decision.
Patent WO-2019232417-A1 (WO)
Title: Compounds and methods for the treatment of toxoplasma gondii infection
Inventor: SIBLEY LAURENCE DAVID
IPC: C07K14/45
Filed: 2019-05-31
Abstract: Provided herein are compounds useful for the treatment of diseases caused by infections of T.  gondii . These compounds, as well as pharmaceutically acceptable salts thereof may be formulated in pharmaceutical compostions including veterinary compositions and may be used in methods of treatment and/or prophylaxis of disease. These compounds work synergistically with the Th1 type immune response including production of interferon gamma (IFN- ϒ ).
Patent WO-2019236539-A1 (WO)
Inventor: SPINELLI DEVON J
IPC: H01F5/00
Filed: 2019-06-04
Abstract: La présente invention concerne des dispositifs électroacoustiques comprenant des compositions à motif MXène sur des substrats polymères à orientation biaxiale et leurs méthodes de fabrication et d'utilisation.
Patent WO-2019236722-A1 (WO)
Inventor: CHATTERJEE SUBROTO
IPC: C07K16/40
Filed: 2019-06-05
Abstract: La présente invention concerne des compositions destinées à être utilisées dans la prévention et le traitement de maladies de la peau ou de troubles associés, d'une inflammation ou de maladies ou de troubles inflammatoires, qui comprennent au moins un inhibiteur de synthèse de glycosphingolipides.
Patent WO-2019246319-A1 (WO)
Inventor: COOK JENNIE
IPC: G06T7/62
Filed: 2019-06-20
Abstract: A method for analyzing a rock sample to determine a mechanical property of the rock sample includes (a) segmenting a digital image volume corresponding to an image of the rock sample. In addition, the method includes (b) partitioning the digital image volume to associate a plurality of voxels in the digital image volume with a plurality of grains of the rock sample. Further, the method includes (c) determining the voxels of the plurality of voxels that are adjacent to each other to identify a plurality of contact interfaces between the grains. Still further, the method includes (d) determining a contact area of each of the contact interfaces using adjacent voxels at the corresponding grain-grain interface. The method also includes (e) determining a number of contact interfaces that each grain of the plurality of grains has with each adjacent grain. Moreover, the method includes (f) determining the one or more mechanical properties of the rock sample based on the number of the contact interfaces of each of the plurality of grains and the contact area of each of the contact interfaces.
Patent WO-2020027949-A1 (WO)
Title: Multidimensional privacy control
Inventor: JURICH JR
IPC: G06Q20/36
Filed: 2019-06-25
Abstract: Systems and methods are disclosed that enable multidimensional privacy control for consumers, to more effectively control their privacy, even while accepting some targeted marketing that provides time-savings, monetary savings, and other benefits. Agreements may involve smart contracts implemented on a blockchain, to provide time-limited access to marketing data, such as purchase histories recorded in receipts held by a digital wallet. The access may be specified in differing tiers of visibility, with certain classes of information withheld, and different types of recipients allowed or blocked. This permits consumers to intelligently select a trade-off between sharing information and receiving value resulting from that sharing, with the consumers in control of the specific type of information shared, and the types of entities that my receive particular information. Thus, privacy may be controlled in a multidimensional manner that is advantageous to consumers.
Patent WO-2020033063-A1 (WO)
Title: Timing offset techniques in wireless communications
Inventor: ABEDINI NAVID
IPC: H04W74/08
Filed: 2019-06-25
Abstract: Methods, systems, and devices for wireless communications are described that provide for multiple timing advance offsets that may be used in communications between wireless devices on a wireless communications system. A first timing advance offset may be a fixed offset that has a predetermined value or is selected from a set of available predetermined values, and a second timing advance offset may be adjustable by a wireless device. The second timing advance offset may be used in cases where relatively large distances between wireless devices are present in a system, where certain fixed timing advances are used in addition to or irrespective of a receiving devices propagation delay, where one or more parent nodes have an associated timing reference, or combinations thereof.
Patent WO-2020006179-A1 (WO)
Title: Compositions and methods associated with haptoglobin related protein
Inventor: COMPER WAYNE
IPC: G01N33/53
Filed: 2019-06-27
Abstract: The present disclosure relates to compositions and methods associated with haptoglobin related protein (HRP), including compositions and methods associated with diagnosis and treatment of renal salt wasting (RSW) and the syndrome of inappropriate anti- diuretic hormone secretion (SIADH), as well as diuretic compositions and associated methods.
Patent WO-2020006472-A1 (WO)
Title: Pause assembly for showerheads
Inventor: ROGERS CRAIG
IPC: B05B1/30
Filed: 2019-06-28
Abstract: The present disclosure relates generally to a showerhead with a pause assembly. The pause assembly can be partially received within a chamber of the housing and positioned between a fluid inlet and a plurality of nozzles to permit flow or substantially reduce flow from the fluid inlet to the plurality of nozzles. The pause assembly includes a valve and a lever coupled to the valve. The lever extends from the housing and movement of the lever in the first direction moves the valve to a first position to permit flow from the fluid inlet to the plurality of nozzles and movement of the lever in a second direction moves the valve to a second position to substantially reduce flow from the fluid inlet to the plurality of nozzles.
Patent WO-2020023337-A1 (WO)
Title: Systems and methods for generating and updating proximal groupings of electronic devices
Inventor: MARINOVIC SRDJAN
IPC: H04W72/00
Filed: 2019-07-22
Abstract: Embodiments described herein generate proximal groupings of wireless signals based upon the temporal persistence and spatial proximity of the wireless signals as observed by a plurality of observer devices. For example, a first observer device may observe a first set of wireless signals at a first timepoint and a second observer device may observe a second set of wireless signals at a second timepoint. The first observer device may again observe a third set of wireless signals at a third timepoint. Based upon these observations, a server may generate a proximal grouping a wireless signals containing a subset of the first, second, third of wireless signals based upon temporal persistence and spatial proximity. Temporal persistence may be based upon the repeated observations of the subset of wireless signals across different timepoints and the spatial proximity may be based upon the proximity of locations of the observer devices.
Patent WO-2021021144-A1 (WO)
Inventor: SHIBATA ALAN
IPC: B41M5/035
Filed: 2019-07-31
Abstract: An optical printhead alignment system may include an optical alignment platform, a camera, a calibration template, and an adjustment handle. The optical alignment platform may capture an image of an edge of a printhead associated with the alignment of the printhead relative to a pressure roller. The calibration template may facilitate calibration of a camera on the optical alignment platform. The adjustment handle may be selectively rotated to adjust an offset of the printhead relative to the pressure roller until the edge of the printhead captured by the camera is aligned with an alignment reticle on the captured image.
Patent WO-2020033793-A1 (WO)
Title: Solid compositions for teeth whitening and anti-microbial effects
Inventor: HUANG CHUN
IPC: A61Q11/00
Filed: 2019-08-09
Abstract: Disclosed herein is a solid composition for oral care comprising at least one whitening agent chosen from chloride isocyanurate and metal salts of hypochlorite; at least one carbonate base; and optionally at least one effervescent acid. Further disclosed herein is a kit comprising the solid composition and an aqueous liquid composition, as well as methods of whitening teeth and/or producing antibacterial effects in the oral cavity comprising mixing the solid composition with an aqueous liquid composition until the solid composition disintegrates to create a mouthwash comprising hypochlorite; and contacting teeth with the mouthwash comprising hypochlorite.
Patent WO-2020036913-A1 (WO)
Inventor: BATES CRAIG
IPC: A61P35/00
Filed: 2019-08-13
Abstract: La présente invention concerne des formes solides de (2-chloro-4-phénoxyphényl)(4-(((3R,6S)-6-(hydroxyméthyl)tétrahydro-2H-pyran-3-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-5-yl)méthanone à base libre, et des procédés de préparation et d'utilisation de celles-ci.
Patent WO-2020047510-A1 (WO)
Inventor: GREY MICHAEL
IPC: A61K38/06
Filed: 2019-08-30
Abstract: Provided herein are compositions and methods of use thereof for the treatment of fungal infections and diseases.
Patent WO-2020069491-A1 (WO)
Inventor: WALDEN CHARLES R
IPC: G06Q20/36
Filed: 2019-09-30
Abstract: L'invention concerne un procédé mis en œuvre par ordinateur, exécuté sur un dispositif informatique et conçu pour effectuer une plateforme de négociation, consistant à : recevoir un ou plusieurs ordres non mis en correspondance pour des actifs financiers de support ; et mettre en correspondance le ou les ordres non mis en correspondance pour exécuter des négociations des actifs financiers de support.
Patent WO-2020106373-A1 (WO)
Title: Methods and systems for linking tokenized data
Inventor: O'SULLIVAN DANIEL
IPC: G06Q20/42
Filed: 2019-10-07
Abstract: Provided are methods and systems for improving data tokenization processes and mobile device data accessibility. A data warehouse may receive first provisioning data for tokenizing a first data set and a device identifier for a mobile device. The tokenized first data set may be stored in a database record associated with the device identifier. The data warehouse may receive second provisioning data for tokenizing a second data set and the device identifier. The data warehouse may then determine that both tokenized data sets are associated with the mobile device based on the device identifier. When the tokenized first data set is used by the mobile device, the data warehouse may notify a network associated with the second data set. The network may update its data processing rules based on the notification.
Patent WO-2021071490-A1 (WO)
Inventor: KANNAN VIGNESH
IPC: B01L3/00
Filed: 2019-10-10
Abstract: L'invention concerne une cassette de distribution qui peut comprendre une languette ayant une caractéristique surélevée sur un corps de la cassette de distribution. La cassette de distribution peut également comprendre une tête de distribution microfluidique. La cassette de distribution peut en outre comprendre une ligne de trace électrique acheminée sur la caractéristique surélevée de la languette qui relie électriquement la languette au niveau de la caractéristique surélevée à la tête de distribution microfluidique.
Patent WO-2020077124-A1 (WO)
Inventor: BARK PAUL
IPC: B60P1/43
Filed: 2019-10-10
Abstract: Systems, devices, and methods for a core lift platform panel (800) comprising: a top layer (820); a core layer (830) comprising: a repeating series of cells (700), wherein the cells comprise a fixed shape throughout the core layer, and wherein the fixed shape is orientated substantially perpendicular to the top layer such that at least one face (880) of the cell is adjacent to the top layer; and a first adhesive component (870) disposed between at least a portion of the top layer and the core layer, wherein the core layer is adhered to the top layer by the first adhesive component.
Patent WO-2020077344-A1 (WO)
Inventor: Dailey Christopher
IPC: G01N33/84
Filed: 2019-10-14
Abstract: Systems and methods for point-of-care determination of blood potassium are provided. The approaches are based on the reaction of ADP and PEP in the presence of potassium ion and pyruvate kinase to produce pyruvate and ATP. In one method, the produced pyruvate is reacted with phosphate and mediator, in the presence of pyruvate oxidase, to yield acetylphosphate and reduced mediator, and the reduced mediator is used to determine the blood potassium using conventional electrochemical methods. In an alternative method, the produced pyruvate is reacted with phosphate and oxygen in the presence of pyruvate oxidase to yield acetylphosphate and hydrogen peroxide, and the hydrogen peroxide is measured optically in accordance with known methods.