baber/WOPTO huggingface dataset:
Patent SG-177226-A1 (SG)
Title: Novel compounds and their effects on feeding behaviour
Inventor: BLOOM STEPHEN ROBERT
Filed: 2007-12-13
Abstract: The invention provides a peptide comprising the amino acid sequence given below, together with use of the peptide and methods associated therewith. The peptide finds particular use as an appetite suppressant and in the treatment of obesity. Xaa I Xaa2 Xaa3 G1y4 Thr5 Phe6 Thr7 Ser8 Asp9 Tyr10 Serl I Lys12 Tyr13 Leul 4 Xaal 5 Xaal6 Xaal7 Xaal8 Xaal 9 Xaa20 Xaa21 Xaa22 Xaa23 Xaa24 Trp25 Leu26 Xaa27 Xaa28Xaa29 Xaa30 Xaa31 Xaa32 Lys33 Asn34 Asn35 Lle36 A1a37; wherein: Xaal is Hist or D-Hisi, Xaa2 is Ser2 or A la2, Xaa3 is Gin3 or Asp3; Xaa 15 Xaal6 Xaal 7 Xaal8 Xaal 9 Xaa20 Xaa21 Xaa22 Xaa23 Xaa24 is: G1 u15 Giul 6 G1u17 Leul8 Vall9 Lys20 Tyr2 IPhe22 Leu23 01u24, GI1115 G1u16 G1ul7 Lett I 8 Vail 9 Lys20 Tyr21 Phe22 Leu23GM24, G1u15 Glu I 6 Giu17 Leu118 Va119 Lys20 Tyr21 Phe22 11e23 G1u24, Glul5 01u16G1u17 Leull 8 Val 1 9 Lys20 Tyr21 Phe22 Ile23 G1n24, G1u15 Glul 6 Glul 7 llel 8 Val 1 9 Lys20 Tyr21 Phe22 Leu23 01u24, 61u15 G1u16 Glu17 tie18 Val I 9 Lys20 Tyr2 1 Phe22 Leu23 GIn24, G1u15 G1u16 G1u17 11e118 Va119 Lys20 Tyr21 Phe22 11e23 G1u24, Glul5 G1u16 Glul 7 11e18 Van 9 Lys20 Tyr21 Phe22 !1e23 0In24. Glul5 G1n16 G1u17 Leul 8 Val 19 Lys20 Tyr21 Phe22 Leu23 G1u24. Gittl 5 G1n16 G1u17 Leul8 Val 19 Lys20 Tyr21Phe22 Leu23 GIn24, Giu15 GIn16 Glul 7 Leul8 Val 19 Lys20 Tyr21 Phe22 11e23 01u24, Glui5 Gin16 Giul 7 Leul8 Vall9 Lys20 Tyr21 Phe22 1.4e23 G1n24, G1u15 Gln 16 Glu I 7 lle18 Va119 Lys20 Tyr21 Phe22 Leu23 Glu24. Glul5 GIn16 Glul 7 11e18 Va119 Lys20 Tyr2 I Phe22 Leu23 G1n24, Giu15 GIn16 G1u17 11e18 Vall 9 Tys20 Tyr2I Phe22 fle23GM24. Glu15 Gin 16 G1u17 Ile18 'Vail 9 Lys20 Tyr2I Phe22 11e23 G1n24, or Asp15 Serl 6 Aral7 An!' 8 A1a19 G1n20 Asp21 Phe22 VaI23 G1n24; Xaa27 Xaa28 Xaa29 Xaa30 Xaa3 I Xaa32 is: Met27 Asn28 Thr29 Lys30 Arg31 Asn32, Tys27 Asn28 A la29 Gly30 Pro3I Ser32. or Lys27 Asn28 Gly29 G1y30 Pro31 Ser32 or a peptide as set out above in which residue Asn34 is replaced with Asp34: or a peptide as set out above in which Xaa3 is G1u3: with the proviso that if Xaal5 Xaal6 Xaal7 Xaal S Xaal 9 Xaa20Xaa21 Xaa22 Xaa23 Xaa24 is Asp15 Ser16 Arg17 Arg 18 Alai 9 01n20 Asp21 Phe22 VaI23 G1n24, - - then Xaa27 Xaa28 Xaa29 Xaa30 Xaa31 Xaa32 is not Me127 Asn28 Thr29 Lys30 Arg3i Asn32.Figure 4.
Patent SG-178047-A1 (SG)
Title: Authentication of security documents, in particular of banknotes
Inventor: GLOCK STEFAN
Filed: 2010-08-11
Abstract: There is described a method for checking the authenticity of security documents, in particular banknotes, wherein authentic security documents comprise security features (41-49; 30; 10; 51, 52) printed, applied or otherwise provided on the security documents, which security features comprise characteristic visual features intrinsic to the processes used for producing the security documents. The method comprises the step of digitally processing a sample image of at least one region of interest (R. o. I.) of the surface of a candidate document to be authenticated, which region of interest encompasses at least part of the security features, the digital processing including performing a decomposition of the sample image by means of wavelet transform (WT) of the sample image. Such decomposition of the sample image is based on a wavelet packet transform (WPT) of the sample image, preferably a so-called two-dimensional shift invariant WPT (2D-SIWPT)
Patent SG-178964-A1 (SG)
Title: Compounds for treating disorders or diseases associated with neurokinin 2 receptor activity
Inventor: BAIN JERALD
Filed: 2010-09-07
Abstract: Compounds, pharmaceutical compositions and methods of treating a disorder or disease associated with neurokinin 2 (NK2) receptor activity.
Patent SG-185330-A1 (SG)
Title: Novel kinase inhibitors
Inventor: DEWDNEY NOLAN JAMES
Filed: 2008-10-14
Abstract: - 106 - NOVEL KINASE INHIBITORSAbstract5 Pyridine and pyrim d ne compounds according to formula (I) wherein RI, R2, R3, R4, R5, X1 and A are as described herein which inhibit Btk. The compounds disclosed herein are useful to modulate the activity of Btk and treat diseases associated with excessive Btk activity. The compounds are further useful to treat10 inflammatory and auto immune diseases associated with aberrant B-cell proliferation such as rheumatoid arthritis. Also disclosed are compositions containing compounds of formula (I) and at least one carrier, diluent or excipient.(No suitable figure)15
Patent SG-185729-A1 (SG)
Title: Oral vaccine comprising an antigen and a toll-like receptor agonist
Inventor: OUAKED NADIA
Filed: 2011-06-02
Abstract: The present invention provides an immunogenic composition comprising one or more antigens and a Toll-like receptor (TLR) agonist in an orally (e.g. sublingually) administered composition.
Patent SG-186250-A1 (SG)
Title: Crystalline forms of kinase inhibitors
Inventor: HOFFMAN DOUG H
Filed: 2011-06-08
Abstract: Citrate salts of N-(4-{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridin-3-yl}phenyl)-N'-(3-fluorophenyl)urea and crystalline forms thereof are suitable pharmaceutical ingredients for pharmaceutical compositions useful in the treatment of disease, for example, cancer.
Patent SG-187121-A1 (SG)
Title: Method to identify a patient with an increased likelihood of responding to an anti-cancer therapy
Inventor: ANDRES HERBERT
IPC: A61K33/243
Filed: 2011-07-18
Abstract: The invention provides methods for identifying patient who may benefit from treatment with an anti-cancer therapy comprising a VEGF antagonist. The invention also provides methods for monitoring a patients' response to the anti-cancer therapy. The invention also provides kits and articles of manufacture for use in the methods.
Patent SG-187589-A1 (SG)
Title: Designer osteogenic proteins
Inventor: BERASI STEPHEN PETER
Filed: 2011-08-17
Abstract: The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.
Patent SG-189999-A1 (SG)
Title: Crossflow type filtering operation method using ceramic filter
Inventor: ZAIMA FUMIYA
Filed: 2011-10-25
Abstract: Provided is a simple filtering operation method capable of conducting a filtering operation without clogging in a ceramic filter for a long period of time, in the operation of filtering fine crystals of terephthalic acid in an oxidation reaction mother liquor obtained in a process of terephthalic acid production by a cross-flow filtration using the ceramic filter. The present invention can be accomplished by conducting an operation for filtering the fine crystals and a back washing operation with a filtrate while maintaining a flowing circulation operation of the oxidation reaction mother liquor under predetermined conditions.
Patent SG-190240-A1 (SG)
Title: Pharmaceutical composition and dosage form comprising dronedarone, and preparation method thereof
Inventor: ABRAMOVICI BERNARD
Filed: 2011-11-10
Abstract: The invention generally relates to a pharmaceutical composition for oral administration, containing, as active principle, a benzofuran derivative having antiarrhythmic activity, in particular dronedarone and the pharmaceutically acceptable salts thereof, and at least one lipid carrier, said pharmaceutical composition being intended to be used in a dosage form of the capsule type, in particular with a hard shell. This pharmaceutical composition and the dosage form comprising such a composition aim to limit the meal effect following oral administration in humans. The lipid carrier allows: the solubilisation of the active principle of the invention; and the shielding thereof from the negative effects of pH in the intestinal tract, thereby allowing same to be spared from the meal effect to a significant extent.
Patent SG-194404-A1 (SG)
Title: Synthesis of purine nucleosides
Inventor: CHUN BYOUNG-KWON
Filed: 2009-12-23
Abstract: A process for preparing phosphoramidate prodrugs or cyclic phosphate prodmgs of nucleoside derivatives, which is a compound, its stereoisomers, salts (acid or basic addition salts), hydrates, solvates, or crystalline forms thereof(No suitable figure)
Patent WO-2016043654-A1 (WO)
Title: Methods of treating graft versus host disease (gvhd) or epidermolysis bullosa (eb) with exosomes
Inventor: LIM SAI KIANG
IPC: C12N5/071
Filed: 2015-03-19
Abstract: We describe the use of exosome such as mesenchymal stem cell exosomes in a method of promoting, restoring or enhancing homeostasis in an individual suffering from graft versus host disease (GVHD) or epidermolysis bullosa (EB). The homeostasis may comprise immune homeostasis such as maintenance of an immune response. The method may comprise administering a therapeutically effective amount of exosome to the individual.
Patent WO-2019045640-A1 (WO)
Title: Full-face flare joint for lined piping system
Inventor: LIM YONG ANN JEFFREY
IPC: F16L19/02
Filed: 2017-08-30
Abstract: A full-face flare joint for a lined piping system having a connector portion of a metal piping being flared radially outwardly at a predetermined angle to form a pipe lap with a first surface and a second surface. The first surface is configured to engage a pipe flange. Further, a pipe lining extends out of the connector portion and is flared radially outwardly over the second surface of the pipe lap thereby forming a liner flare. A full-face flare component with a bottom portion is attached to the liner flare so that the bottom portion of the component forms an angle of about 90º with an inner surface of the pipe lining.
Patent WO-2021080516-A1 (WO)
Title: Method of forming a vasculature structure and a vasculature structure thereof
Inventor: CHING TSZ HIM TERRY
IPC: A61L27/52
Filed: 2020-10-23
Abstract: There is provided a method of forming a vasculature structure. The method includes: providing a microfluidic mold comprising a microchannel network made of a hydrogel matrix; forming a layer of hydrogel on an inner wall of the microchannel network of the microfluidic mold to form a perfusable hydrogel network; and removing the perfusable hydrogel network from the microfluidic mold to form the vasculature structure, the vasculature structure being free-standing. There is also provided a corresponding vasculature structure formed according to the method.
Patent WO-2021107877-A1 (WO)
Inventor: ZHOU WEIBIAO
IPC: A61P3/00
Filed: 2020-11-26
Abstract: There is provided a baked confection comprising a plant extract comprising > 5 weight % (wt %) anthocyanin, based on the total weight of the plant extract. There is also provided a method of treating and/or preventing a metabolic syndrome disorder, or a method of preventing or reducing a postprandial rise in blood glucose level wherein the method comprising administering the baked confection to a patient in need thereof. In one embodiment, the plant extract is an anthocyanin-rich black rice extract powder (ABREP) and the baked confection is an ABREP fortified cakes.
Patent TN-2010000305-A1 (TN)
Title: Pyrrolopyrimidines and pyrrolopyridines
Inventor: LEBLANC CATHERINE
IPC: C07D487/04
Filed: 2010-06-30
Abstract: Compounds of formula (I) in free or salt or solvate form, wherein X, T1, T3 and T4 have the meanings as indicated in the specification, are useful for treating diseases mediated by the ALK-5 and/or ALK-4 receptor. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
Patent TN-2011000456-A1 (TN)
Title: Treatment of pancreatic cancer
Inventor: CHAPMAN MARK S
IPC: A61P35/04
Filed: 2011-09-09
Abstract: The present invention relates to the field of oncology and relates to use of (S)-N- (3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1 -(2,3- dihydroxypropyl)cyclopropane-1 -sulfonamide or a pharmaceutically acceptable salt thereof or N-(4-(2-fluoro-4-iodophenylamino)-1,5-dimethyl-6-oxo-1,6-dihydropyridin- 3-yl)cyclopropanesulfonamide or a polymorph thereof, or a pharmaceutically acceptable salt thereof, or pharmaceutical compositions comprising the same, for the preparation of a medicament for the treatment of pancreatic cancer. Further, the present invention provides methods for administering a compound disclosed herein to an individual in need thereof by administering (S)-N-(3,4-difluoro-2-(2-fluoro-4- iodophenylamino)-6-methoxyphenyl)-1 -(2,3-dihydroxypropyl)cyclopropane-1 - sulfonamide or a pharmaceutically acceptable salt thereof or N-(4-(2-fluoro-4- iodophenylamino)-1,5-dimethyl-6-oxo-1,6-dihydropyridin-3- yl)cyclopropanesulfonamide, or a polymoph thereof, or a pharmaceutically acceptable salt thereof, or pharmaceutical compositions comprising the same.
Patent TN-2013000082-A1 (TN)
Title: A novel reverse osmosis water treatment system that rationalizes the wasted water as a result of water treatment
Inventor: MUHSEN HUSSEIN MAHMOUD ABU HAIFA
IPC: C02F1/44
Filed: 2013-02-28
Abstract: The present invention provides a household water treatment system by harnessing the Reverse Osmosis (RO) characteristic, wherein such system is characterized by rationalizing the amount of wasted water left after the water treatment process completely without negatively affecting the system components and by increasing the efficiency and quality levels as well as the durability of the system's components. The system of the present invention essentially comprises a water feeding and draining unit, a household water treatment unit with a special holder for an RO membrane to keep vibrating, a fresh water storage unit, a drain water storage unit, and a dual inlet water faucet. The system of the present invention stores the salt water resulted from the household water treatment in said drain water storage unit in order to be used in domestic processes that do not need fresh water such such as washing fruits and vegetables, and washing kitchen utensils. The traditional drain restrictor is modified in the system of the present invention to a self-calibrating drain restrictor to maintain a constant operating pressure on the RO membrane, and to prevent blockages in such restrictor as a result of calcification. In the system of the present, continuous water feeding for said household water treatment unit is maintained through using same diameters of feeding passages and through designing a mixing chamber in a way that permits good water feeding for both the main water faucet when operated, and the household water treatment unit.
Patent TN-2013000251-A1 (TN)
Title: Combination of acylated glucagon analogues with insulin analogues
Inventor: FOSGERAU KELD
IPC: A61P3/10
Filed: 2013-06-11
Abstract: The invention relates to methods for treating metabolic disorders, including diabetes by using a combination of an acylated glucagon analogue and an insulin analogue. The invention also features a kit that includes an acylated glucagon analogue and an insuline analogue.
Patent TN-2013000347-A1 (TN)
Title: Production method of optically active dihydrobenzofuran derivative
Inventor: YAMANO MITSUHISA
IPC: C07F15/00
Filed: 2013-08-16
Abstract: Provided is a production method of an optically active dihydrobenzofuran derivative. A production method of an optically active form of a compound represented by the formula: wherein each symbol is as defined in the specification, or a salt thereof and the like.
Patent TN-2015000131-A1 (TN)
Title: Mise au point d'un procédé enzymatique de production de sirop de sucres invertis à partir de déchets industriels de dattes.
Inventor: Chemseddine MAATKI
IPC: C13K3/00
Filed: 2015-04-06
Abstract: La présente invention concerne le domaine technique de la valorisation des déchets des dattes. La présente invention concerne plus précisément, mais non exclusivement la fabrication des sirops de sucres invertis à partir des déchets industriels de dattes. L'invention concerne la mise au point d'un procédé pilote de valorisation de déchets industriels de dattes pour la production de sirop de sucres invertis par voie enzymatique.Selon l'invention, le procédé comprend : • Une étape d'extraction du saccharose à partir des dattes par diffusion, • Une étape de transformation enzymatique et • Une étape d'ultrafiltration. Nous avons réussi à produire lors de cette invention un sirop de sucre renfermant 150 g/L de sucres réducteurs.
Patent TN-2017000091-A1 (TN)
Title: Method of insurance claim validation, reconciliation check and action by means of entry centralization at expert level
Inventor: MAHMOUD ALJAN
IPC: G06Q40/08
Filed: 2017-03-16
Abstract: A method and system of consolidating vehide insurance daims entry and management in a central electronic daim repository fed, at the lowest level, by insurance experts; and fulfilling nove! ways of daim validation, reconciliation, check and action, valuable to the insurance industry stockholders. The system will allow experts to be notified of every inspection job at origination. The central daim repository will then act as a one version of the truth for all daim related information such as vehide, driver and accident details, pictures as well as repair related information such invoices and repair shop and spare parts suppliers' identity. Our method also details a novel approach to daim paper trail monitoring and logistics, fraud prevention and mitigation as well as secure data transmission relying on the central daim repository.
Patent WO-2016099409-A1 (WO)
Inventor: BOLKENT SEHNAZ
IPC: A61K38/00
Filed: 2014-12-23
Abstract: The invention features methods and pharmaceutical compositions containing antimicrobial peptides (e.g. bactenecin) that can selectively interact with the cell surface of cancer cells to induce cell death. The methods and pharmaceutical compositions of the invention may be used to treat various cancers, preferably, breast cancer.
Patent WO-2021230845-A1 (WO)
Title: Biopolymer production with fraction of whey components and biodegradable/biocompatible membrane fabrication method
Inventor: YUKSEL IMER DERYA
IPC: C08J5/00
Filed: 2021-05-06
Abstract: The invention relates to the production of biopolymer with a fraction of whey components by cyclic approach via an enzymatic extractive ceramic membrane reactor (EECeMR) and a process for the fabrication of biodegradable/biocompatible membranes.
Patent WO-2022125039-A1 (WO)
Title: A multi-part and encrypted message transmission system
Inventor: TANRIVERDI HAYATI
IPC: H04L67/10
Filed: 2021-12-06
Abstract: The present invention relates to a system (1) for realizing messagings between devices of mobile device users over communication channels such as Bluetooth or Wi-Fi Direct in a direct, multi-part and encrypted way.
Patent WO-2013162487-A1 (WO)
Title: Dispositif permettant de plâtrer des esconsons de fenêtre et de porte
Inventor: PYSMENSKYI SERGII
IPC: E04F21/06
Filed: 2013-03-27
Abstract: La présente invention concerne un dispositif permettant de plâtrer des esconsons de fenêtre et de porte. Le dispositif comprend un élément amovible et réglable (2) permettant d'égaliser le plâtre, tel qu'une règle de plâtrage, ainsi qu'une structure angulaire (1), composée de deux éléments linéaires (3, 4) fixés fermement l'un à l'autre, un élément (3) étant aplatis et un élément (4) étant situé à l'emplacement du joint des éléments (3,4). L'élément (4) comprend une barre (5) conçue pour effectuer un mouvement coulissant et pour être fixée. La partie d'extrémité de travail (6) de la barre (5) est conçue pour assurer le contact coulissant avec la surface du coin externe de la fenêtre ou de la porte ou la limite du déplacement transversal-perpendiculaire du dispositif lors du déplacement. La présente invention améliore l'efficacité de production, la performance et la sécurité du plâtrage d'esconsons de fenêtre et de porte, améliore la qualité des esconsons de porte et de fenêtre plâtrés, accroît la précision et la cohérence de l'esconson (tour), réduit les exigences de qualification professionnelle pour les plâtriers et réduit le coût de la main-d'œuvre tout en augmentant sa rentabilité globale.
Patent WO-2020219001-A1 (WO)
Title: Vertical axis-type wind turbine assembly
Inventor: SUHIN VLADIMIR STEPANOVICH
IPC: F03D3/06
Filed: 2019-08-13
Abstract: The invention relates to vertical axis-type wind turbine assemblies. A vertical axis-type wind turbine assembly comprises a mast with an electric generator, and a wind rotor in the form of crossbeams extending radially from the mast and having vertical blades mounted thereon that have an aerodynamic shape which curves convexly towards the rotational shaft of the wind rotor. Each blade is equipped with a secondary blade which is provided with slats and is mounted relative to the blade such as to curve convexly towards the rotational shaft and to be offset by 1/3 of the chord towards the rotational shaft of the wind rotor and by 2/3 of the chord in the direction of rotation of the wind rotor. Each blade and each secondary blade is mounted on a crossbeam such as to allow variation of their angle of attack and to be fixable at a given angle. The invention is directed toward increasing capacity without increasing the overall dimensions.
Patent WO-2004082497-A1 (WO)
Title: Appareil pour traiter des tissus au moyen de dispositifs a electrodes implantees
Inventor: KELLY AMY C
IPC: A61B19/00
Filed: 2004-02-17
Abstract: L'invention concerne un appareil pour traiter des tissus par l'implantation d'une pluralité de dispositifs à électrodes à l'intérieur du tissu à traiter et par l'exposition de dispositifs à électrodes implantées à l'action d'ondes RF émises par un dispositif à électrodes séparées. On peut ainsi traiter une région plus vaste d'un tissu d'une façon utilisée d'ordinaire avec un dispositif à électrodes séparées. De plus, des dispositifs à électrodes implantées peuvent créer une carte qui permet d'assurer l'évolution du traitement, à gérer lors des opérations consécutives. Les dispositifs à électrodes implantées peuvent être acheminés jusqu'au tissu par divers moyens, par exemple, par le détachement des dispositifs à électrodes d'un ou plusieurs dispositifs d'acheminement. Ainsi, un fil métallique central à raccordement détachable par procédé électrolytique peut s'utiliser pour séparer le ou les dispositifs à électrodes et ledit fil métallique. L'invention concerne aussi des pistons à raccordement détachable par procédé mécanique.
Patent WO-2004103470-A1 (WO)
Title: Medical system including a novel bipolar pacing pair
Inventor: BROWN MARK L
IPC: A61N1/05
Filed: 2004-05-13
Abstract: An implantable electrical medical system comprises a low voltage cathode electrode assembly, including a cathode surface adapted for intimate contact with electrically active tissue, and a low voltage anode electrode assembly, including an anode surface and a porous layer extending over the anode surface. The cathode surface and the anode surface function as a bipolar pair for pacing and the porous layer extending over the anode surface allows conduction therethrough and prevents the anode surface from contacting the electrically active tissue in order to prevent anodal stimulation.
Patent WO-2005002283-A1 (WO)
Inventor: CLOTHIER BRIAN L
IPC: H05B6/00
Filed: 2004-06-25
Abstract: A heat storage unit (2) includes a body having a passage (12) formed therein through which a flowable product passes. A heatable element (10) is incorporated within the body of the heat storage unit (2) in thermal communication with the passage (12). Meanwhile, a heat-retentive material (8) is in thermal communication with the heatable element (10). The heatable element (10) includes either a magnetically-compatible material or a microwave-compatible material that is heated by locating the heatable element in a field (F) generated by a charging device (6), for example.