baber/WOPTO huggingface dataset:
Patent CA-2302919-C (CA)
Inventor: WAMPLER SCOTT D
IPC: A61B18/12
Filed: 2000-03-29
Granted: 2010-06-22
Abstract: An energy based surgical device for the application of ultrasonic energy and Radio Frequency energy is disclosed. The surgical device has a housing and an acoustic assembly having an electrically conductive waveguide. The waveguide has a solid core and extends from the housing. A conductive element for conducting Radio Frequency energy to the waveguide is operably coupled to the waveguide. The distal end of the waveguide of the acoustic assembly has an end effector for the conduction of ultrasonic energy or Radio Frequency energy. A number of novel end effectors for the emulsification and cauterization of tissue are described.
Patent CA-2304624-C (CA)
Title: Tetrahydrofuran phosphate- and hydroxy esters, as prodrugs for the corresponding antifungal agent
Inventor: GIRIJAVALLABHAN VIYYOOR M
IPC: C07F9/6518
Filed: 1998-09-22
Granted: 2007-06-19
Abstract: A compound of formula (I) wherein G is H or PO3H2 or a pharmaceutical acceptable salt thereof, pharmaceutical compositions containing such compounds and method of using such compounds or pharmaceutical compositions containing them to treat or prevent fungal infection are disclosed.
Patent CA-2309532-C (CA)
Inventor: IMAMURA TADASHI
IPC: B60B23/00
Filed: 2000-05-25
Granted: 2005-03-01
Abstract: A wheel with a damper for an automobile includes a rim, a disk, and a damper. The damper includes a rubber member. The rubber member includes a first portion and a second portion. The first portion performs mainly an elastic shear deflection and the second portion acts as a stopper. The first portion extends in an axial direction of the wheel and has an inside surface and an outside surface which contact a space and are not constrained. The end surfaces of the first portion extend perpendicularly to the axial direction of the wheel. A vibrational system having a spring of the first portion of the rubber member and a mass of an automobile is designed so as to have a first natural frequency in a range of 6 - 12 H, preferably, in a range of 8 - 10 Hz.
Patent CA-2309755-C (CA)
Title: Hormone-dependent forms of the adeno-associated virus, rep proteins, dna sequences coding for them, vectors containing them, and regulatory methods of their intracellular activity
Inventor: RINAUDO CIRA
IPC: C12N15/86
Filed: 1998-11-20
Granted: 2007-04-10
Abstract: The subject matters of this invention are the hormone-dependent forms of Rep 78 and Rep 68 proteins of the Adeno-associated virus (AAV), obtained by the fusion of their specific mutants with the hormone binding domain (HBD) of steroid hormone receptors, and the DNA sequences coding for them. The invention also refers to a method for the hormonal regulation of the activity of the fusion products Rep78/68-HBD, inserted into eucaryotic cells utilising viral or non-viral systems, in order to direct the stable integration of DNA sequences in specific regions of the host human genome for therapeutic purposes. The fusion products Rep78/68-HBD are also utilised to generate viral hybrid vectors (i.e. adenovirus vectors AAV) and for generating recombinant vectors AAV.
Patent CA-2312234-C (CA)
Title: Use of methylnaltrexone and related compounds
Inventor: MOSS JONATHAN
IPC: A61K31/485
Filed: 1998-11-03
Granted: 2005-03-22
Abstract: A method for preventing or treating opioid induced side effects including dysphoria, pruritus, urinary retention and gastrointestinal dysfunction and non-opioid induced changes in gastrointestinal motility. The method comprises administering methylnaltrexone or another quaternary derivative of noroxymorphone to a patient prior to the administration of an opioid or after the onset of side effects induced by the administration of an opioid, wherein the methylnaltrexone or quaternary derivative is administered by the route selected from the group consisting of intravenous, intramuscular, transmucosal, transdermal, and oral administration, preferably administered orally in an enterically coated form.
Patent CA-2330093-C (CA)
Inventor: MAUL ROBERT
IPC: C09D7/12
Filed: 2001-01-04
Granted: 2009-02-24
Abstract: A flowable and pumpable aqueous semifinished product of gassing stability for the production of paints and lacquers comprising water, a pre-stabilized metallic pigment and an anticorrosive pigment.
Patent CA-2338214-C (CA)
Inventor: SANNER MARK ALLEN
IPC: A61P25/14
Filed: 1999-06-28
Granted: 2006-08-01
Abstract: L'invention concerne les composés de la formule (I) dans laquelle A représente alkylène C3-C5 non ramifié facultativement substitué par alkyle C1-C6; X représente O, S, NH ou N(alkyle C1-C6); Y représente O, S, NH ou N (alkyle C1-C6); R représente un cycle à liaison C, de 4 à 6 éléments, un groupe non aromatique hétérocyclique contenant un hétéro-atome d'azote, ledit groupe étant facultativement substitué par 1, 2 ou 3 substituants choisis chacun indépendamment parmi alkyle C1-C6, alcényle C2-C6, cycloalkyle C3-C7, aryle, het, -CO2(alkyle C1-C6), -CO(het), -CONR5R6 et -CO(aryle), ledit alkyle et ledit alcényle étant facultativement substitués par 1 ou 2 substituants choisis chacun indépendamment parmi cycloalkyle C3-C7, aryle, het, -O(aryle), -O(alkyle C1-C2) aryle, -CO(het), -CONR5R6 et -CO(aryle); lesquels composés sont des inhibiteurs des enzymes rotamase notamment FKBP-12 et FKBP-52. Les composés modèrent par conséquent la régénération et l'excroissance neuronales, ils peuvent être utilisés dans le traitement de troubles neurologiques ayant pour origine des maladies neurodégénératives ou d'autres troubles impliquant des lésions nerveuses.
Patent CA-2339914-C (CA)
Inventor: BENZ VOLKER
IPC: C08J5/12
Filed: 2001-03-07
Granted: 2008-08-05
Abstract: Flat composites of plastic are manufactured by thermal adhesive bonding of at least two plastic parts which are heated at their surfaces and which comprise a base material coated with a plastic layer, wherein the Vicat softening point of the plastic of layer is 5 to 40°C lower than that of the base material, wherein the base material has a thickness of 1 to 200 mm and the plastic layer has a thickness of 5 to 400 µm, and each of the parts is heated on the surfaces coated with the plastic layer and then welded under pressure.
Patent CA-2339998-C (CA)
Inventor: MULLER GERALD
IPC: B60S9/08
Filed: 1999-08-28
Granted: 2008-01-22
Abstract: The invention relates to a supporting device, which comprises a larger clearance for the spindle, whereby the foot receiving device should comprise a high level of stability. The foot-receiving device (1) comprises a component, which occludes the inner sleeve (8). Said component comprises an opening (3) for admitting the spindle (11), at least one bracing element (5, 5a, b, 6, 6a, b) located on the upper and/or bottom sides thereof, and two opposing bearing points (4a, 4b) for the support foot.
Patent CA-2341206-C (CA)
Title: Antiradiation concrete and antiradiation shell
Inventor: VANVOR DIETER
IPC: G21C1/30
Filed: 1999-08-11
Granted: 2007-10-23
Abstract: To achieve a shielding action which absorbs as much heat and radiation as possible, according to the invention an antiradiation shell (2) has a wall region (2a to 2z) which is formed from an antiradiation concrete (22a to 22z) which is provided with a first, boron-containing aggregate with a grain size of up to 1 mm and with a second, metallic aggregate with a grain size of up to 7 mm. In a first embodiment, the content of first, boron-containing aggregate in the antiradiation concrete (22a) is at least 5.0% by weight, in particular at least 7.8% by weight. In a second embodiment, the proportion of the second, metallic aggregate in the antiradiation concrete (22b) is from 80 to 90% by weight, in particular 85 to 89% by weight. In this case, the proportion of the first, boron-containing aggregate may lie in the range between 1.0 and 1.5% by weight.
Patent CA-2346769-C (CA)
Title: Implants comprising combinations of allogeneic cells for use in cancer treatment
Inventor: GRANGER GALE A
IPC: A61K35/17
Filed: 1998-10-09
Granted: 2004-09-14
Abstract: This invention provides methods and compositions for treating tumors by implanting near the tumor and alloactivated cell population. The cell population is made up of a plurality of third-party donor cells that have been cultured together ex vivo, and harvested near the time of peak cytokine secretion. Once placed in the tumor bed, the alloactivated cells recruit active participation of the host, which then reacts against the tumor and provides a level of ongoing protection. Employing multiple third party donor cells confers particular advantages in terms of effectiveness, timing, and ease of use.
Patent CA-2347424-C (CA)
Title: Utilisation de dextrane lie par covalence a des groupes charges pour le ciblage selectif de tumeur au moyen d'administration locale, intratumorale ou endocavitaire
Inventor: HOLMBERG ANDERS
IPC: A61K47/48
Filed: 1999-10-12
Granted: 2009-12-08
Abstract: L'invention concerne un composé destiné à une administration locale, c'est-à-dire intratumorale ou intracavitaire, qui permet le ciblage de tumeurs. Ce composé comprend du dextrane, dont la charge a été modifiée au moyen d'une liaison covalente de groupes chargés, tels que des acides aminés chargés. Il comporte également un groupe fonctionnel destiné au traitement de la tumeur ou à sa représentation sous formes d'images.
Patent CA-2347757-C (CA)
Title: Method for producing (+)-exo-6-phenyl-3-azabicyclo-[3.2.0]heptanes
Inventor: VIERGUTZ WOLFGANG
IPC: C07D/
Filed: 1999-10-13
Granted: 2005-05-17
Abstract: The invention relates to a method for producing (+)-exo-6-phenyl-3--azabicyclo-[3.2.0]heptanes of formula (I) in which R represents hydrogen, chlorine, bromine, fluorine or methoxy. The inventive compounds are characterized in that a bisallyl ammonium salt of formula (II), in which R has the above-mentioned meanings and X- represents an anion, is photo-cyclized in an inert solvent while adding a sensitizer in a glass apparatus, and the selected (+)-exo-isomer (I) is precipitated as ditoluoyl tartrate using (-)-ditoluoyl tartaric acid from the obtained mixture, and this ditoluoyl tartrate is optionally recrystallized out of an alcohol/water mixture.
Patent CA-2349168-C (CA)
Title: Hyaluronic acid gel, method of its production and medical material containing it
Inventor: KANEKO HIROSHI
IPC: C08J3/075
Filed: 1999-11-09
Granted: 2009-01-06
Abstract: A gel made of hyaluronic acid alone which is hardly soluble in a neutral aqueous solution and has fluidity enough to be easily ejectable from an injector
Patent CA-2354861-C (CA)
Inventor: UROS RAYMOND
IPC: A01F15/10
Filed: 2001-08-08
Granted: 2005-07-12
Abstract: A baler pick-up includes a pair of support wheels, each of which is connected to the pick-up by a mounting arrangement permitting the wheel to be selectively moved from a working position outboard of the pick-up to an inboard, elevated transport or non-working position. Each mounting arrangement comprises a holder fixed to the pickup and including a transverse pipe and a projection formed from a plate and spaced outwardly from and end of the pipe. The arrangement further comprises a wheel mounting bracket including a cylindrical tube pivotally and slidably received in the pipe and in a hole provided in the projection, the tube carrying a ring captured between the end of the pipe and the projection and containing a throughbore aligned with one of a pair of crossbores provided in the tube and receiving a linchpin bolt for retaining the wheel mounting bracket so as to dispose the wheel in a selected one of its positions.
Patent CA-2356009-C (CA)
Title: Vascular endothelial growth factor-x
Inventor: GORDON ROBERT DOUGLAS
IPC: A61K38/18
Filed: 1999-12-21
Granted: 2011-09-20
Abstract: There is provided a novel vascular endothelial growth factor, herein designated VEGF-X, in addition to the nucleic acid molecule encoding it, a host cell transformed with said vector and compounds which inhibit or enhance angiogenesis. Also provided is the sequence of a CUB domain present in the sequence of VEGF-X which domain itself prevents angiogenesis and which is used to treat diseases associated with inappropriate vascularisation or angiogenesis.
Patent CA-2357744-C (CA)
Title: Potassium salt of (s)-omeprazole
Inventor: NILSSON MATHS
IPC: C07D401/12
Filed: 2000-01-18
Granted: 2009-06-16
Abstract: The present invention relates to a novel form of 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H--benzimidazole, known under the generic name omeprazole. More specifically, it relates to a novel crystalline form of the potassium salt of the (S)- enantiomer of 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole. The present invention also relates to processes for preparing such a form of the potassium salt of (S)- omeprazole and pharmaceutical compositions containing it.
Patent CA-2359742-C (CA)
Title: Method for calculating transducer capacitance to determine transducer temperature
Inventor: KRAMER KENNETH S
IPC: G01K1/00
Filed: 2001-10-17
Granted: 2010-09-28
Abstract: A method for calculating the capacitance of a transducer (Co) without knowing the exact resonance frequency of a transducer/blade combination is achieved by sweeping across a broad frequency range which contains resonant and non-resonant frequencies where Co can be measured. A pre-defined frequency range is set independently of the resonance frequency of a specific transducer/blade combination. Co of the transducer/blade is measured at several different frequencies within the pre-defined frequency range to ensure that invalid Co measurements are disregarded, and the temperature of the transducer is calculated based on valid Co measurements. The determined transducer temperature, based on Co measurements, can be used to optimize performance and/or provide a safety shutdown mechanism for the generator.
Patent CA-2363284-C (CA)
Title: Process for synthesizing n-(mercaptoacyl)-amino acids from alpha-substitute acrylic acids
Inventor: MONTEIL THIERRY
IPC: C07D317/50
Filed: 2001-11-08
Granted: 2012-04-03
Abstract: New process for preparation of N-(mercaptoacyl)amino acid derivatives (I), comprising a Michael addition reaction of a thioacid (IV) with an  alpha -substituted acrylamide derivative (V). New process for preparation of N-(mercaptoacyl)amino acid derivatives of formula (I), comprising a Michael addition reaction of a thioacid of formula (IV) with an  alpha -substituted acrylamide derivative of formula (V). R1 = phenyl or 3,4-methylenedioxyphenyl; R2 = H or 1-6C alkyl; R3 = R2 or phenyl 1-6 alkylene; and R4 = acyl.
Patent CA-2365209-C (CA)
Title: Method for micro-fabricating a pixelless infrared imaging device
Inventor: BUCHANAN MARGARET
IPC: H01L27/146
Filed: 2001-12-14
Granted: 2012-03-20
Abstract: The present invention relates to a method for micro-fabricating a pixelless thermal imaging device. The imaging device up-converts a sensed 2-dimensional M/FIR image into a 2-dimensional image in the NIR to visible spectrum in dependence thereupon. A plurality of layers forming an integrated QWIP-LED wafer are crystallographically grown on a surface of a first substrate. The layers comprise an etch stop layer, a bottom contact layer, a plurality of layers forming a QWIP and a LED, and a top contact layer. At the top of the QWIP-LED wafer an optical coupler such as a diffraction grating for coupling at least a portion of incident M/FIR light into modes having an electric field component perpendicular to quantum wells of the QWIP is provided. In following processing steps the first substrate and the etch stop layer are removed. Various different thermal imaging devices are manufactured by changing the order of manufacturing steps, omitting some steps or using different materials. Therefore, it is possible using a same manufacturing equipment for producing a large variety of different imaging devices considerably reducing manufacturing costs.
Patent CA-2365285-C (CA)
Inventor: MORELL MATTHEW
IPC: C12N15/82
Filed: 2000-04-28
Granted: 2013-07-09
Abstract: The present invention provides isolated nucleic acid molecules encoding wheat starch synthases, and probes and primers derived therefrom, which are useful in the modificaiton of plant starch content and/or composition, and for screening plant lines to determine the presence of natural and/or induced mutations in starch synthase genes which affect starch content and/or composition. More particularly, the isolated nucleic acid molecules of the present invention further provide for the screening-assisted breeding of plants having desirable starch content and/or composition, in addition to providing for the direct genetic manipulation of plant starch content and/or composition.
Patent CA-2368354-C (CA)
Inventor: LYNCH MARY G
IPC: A61M25/00
Filed: 2000-04-26
Granted: 2009-02-17
Abstract: L'invention concerne des dispositifs de dérivation et un procédé pour décomprimer en continu une pression intraoculaire élevée dans des yeux atteints de glaucome, par dérivation de l'excès d'humeur aqueuse provenant de la chambre antérieure de l'oeil dans le canal de Schlemm. Une perméabilité postopératoire peut être maintenue à l'aide d'un dispositif de dérivation à demeure qui relie chirurgicalement le canal à la chambre intérieure. Les dispositifs de dérivation assurent un écoulement unidirectionnel ou bidirectionnel de l'humeur aqueuse dans le canal de Schlemm.
Patent CA-2368600-C (CA)
Inventor: PAINTER JEFFREY DONALD
IPC: C09B63/00
Filed: 2000-04-18
Granted: 2005-04-05
Abstract: A process for forming a non-staining colored composite particle suitable for incorporation in a bleach-containing or a non-bleach-containing liquid detergent composition is disclosed. The process includes the steps of forming a colored liquid dispersion of pigment particles in a first liquid medium wherein the size of the pigment particles in the colored liquid dispersion is no greater than about µm. The process includes the step of mixing the colored liquid dispersion with a polymeric material and a second liquid medium to form a sprayable colored polymeric material. The process also includes the step of spraying the colored polymeric material on a composite particle and forming a colored polymeric coating on the composite particle. A  non-staining colored particle and a liquid ADW detergent composition are also disclosed.
Patent CA-2374480-C (CA)
Inventor: CODY IAN ALFRED
IPC: C10G65/04
Filed: 2000-05-16
Granted: 2009-07-14
Abstract: The process is drawn to producing a lubricating oil basestock having at least 90 wt % saturates and a VI of at least 105 in unit (42) then the hydroconverted raffinate is conducted through line (46) to heat exchanger (48).
Patent CA-2374525-C (CA)
Inventor: CHUENG JOSEPHINE H
IPC: C04B24/24
Filed: 2000-05-26
Granted: 2008-12-16
Abstract: A method for improving early strength of cements comprising introducing into a cement, preferably during the grinding thereof, (a) at least one water reducer comprising a polyoxyalkylene polymer; (b) a sugar; and (c) an alkali or alkaline earth metal chloride. In further exemplary embodiments, the polyoxyalkylene polymer preferably comprises a comb polymer having a backbone and pendant groups. Optionally, an amine may be included with the additives. Exemplary additives and cements and cementitious compositions, preferably blended cements, and more most preferably pozzolanic cements, comprising the additives are also disclosed.
Patent CA-2384140-C (CA)
Title: Robinet a deux becs avec element de securite
Inventor: FUNG HUGH YEAN
IPC: F16K31/60
Filed: 2000-09-08
Granted: 2009-07-14
Abstract: L'invention porte sur un robinet (4) comprenant un corps (6) dans lequel est placé un clapet (14), une poignée d'actionnement (12) montée sur le corps et couplée au clapet, un bouton (42) de sécurité qui est asservi à la poignée et/ou au clapet, cet agencement étant conçu de sorte que le clapet puisse être ouvert seulement après activation du bouton de sécurité.
Patent CA-2391625-C (CA)
Inventor: CAVAZZA CLAUDIO
IPC: A61K31/722
Filed: 2000-11-14
Granted: 2009-06-30
Abstract: A composition is disclosed suitable for the prevention and/or treatment of disorders due to abnormal lipid metabo-lism, such as hypercholesterolaemia, atherosclerosis, hyperlipidaemia and obesity, and which can therefore take the form of a dietary supplement or of an actual medicine, comprising as characterising active ingredients: (a) propionyl L-carnitine or a pharmacologi-cally acceptable salt thereof, and (b) chitosan or its derivatives and congeners.
Patent CA-2393522-C (CA)
Inventor: WONG JOE Y
IPC: G01H1/00
Filed: 2002-07-15
Granted: 2005-05-17
Abstract: A method for determining if deterioration in structural integrity of a pressure vessel, having both sensor means and oscillator means affixed to or embedded in said exterior surface thereof. An electrical current is provided to the oscillator means so as to cause said oscillator means to oscillate and produce a mechanical disturbance to the exterior surface and cause a detectable natural frequency response of said pressure vessel. The resultant natural frequency response is detected and recorded. After a period of elapsed time, the natural frequency response is again obtained. It is compared with the recorded natural frequency response first obtained, and if there be a difference therebetween, such as a shift in the frequencies at which the natural resonances occur, or a decrease or increase in the amplitude of one or more of the natural frequency resonances, then a flag is raised. An apparatus for determining if deterioration in structural integrity of a pressure vessel, and a pressure vessel, is further disclosed.
Patent CA-2394563-C (CA)
Title: Foamed isocyanate-based polymer having improved hardness properties and process for production thereof
Inventor: VAN HEUMEN JEFFREY D
IPC: C08L101/00
Filed: 2001-07-30
Granted: 2010-01-26
Abstract: In one of its aspects, the present invention relates to foamed isocyanate-based polymer derived from a reaction mix-ture comprising an isocyanate, an active hydrogen-containing compound, a dendritic macromolecule and a blowing agent; wherein at least a 15 % by weight of the dendritic macromolecule may be mixed with a polyether polyol having an OH number less than about 40 mg KOH/g to form a stable liquid at 23 °C. The dendritic macromolecule confers advantageous load building characteristics to the foamed isocyanate-based polymer and may be used to partially or fully displace the use of conventional copolymer polyols used.  A process for production of a foam isocyanate-based polymer and a process for conferring loading building properties to a foamed isocyanate-based polymer are also described.
Patent CA-2395581-C (CA)
Inventor: BODE JEFFREY
IPC: B01D39/16
Filed: 2001-01-04
Granted: 2006-08-22
Abstract: A subterranean filter to remove particles from production fluid in a well includes a perforated inner member, at least one filter membrane made of a non-woven polymer material and a metal braided layer installed around the membrane and inner member to provide a filter having improved permeability and resistance to chemical and physical forces.
Patent CA-2399862-C (CA)
Title: Systeme d'antenne intelligente distribuee
Inventor: LI JUN
IPC: H04B7/06
Filed: 2001-01-12
Granted: 2008-10-21
Abstract: L'invention concerne un système à antenne directionnelle intelligente distribuée comprenant des série d'antennes formées de N unités d'antennes, N émetteurs-récepteurs radioélectriques et des câbles de connexion. Les N unités d'antenne et les N émetteurs-récepteurs sont répartis en petits groupes de couverture selon la charge privée, puis chaque groupe d'unité d'antenne est réparti selon les besoins de couverture sur différents emplacements dans une zone de couverture ayant une station de base pour communication mobile. Ce système comprend en outre une pluralité de constructions et des étages différents dans les mêmes constructions ainsi que des processeurs de signaux numériques bande de base communs identiques. Chaque groupe d'unités d'antenne peut recevoir entre 1 et M unités. L'invention permet de développer l'antenne intelligente, d'améliorer la couverture tout en augmentant la performance du système et en réduisant le coût.