baber/WOPTO huggingface dataset:
Patent EA-201991961-A1 (EA)
Title: Ингибитор atr киназы для применения в способе лечения гиперпролиферативного заболевания
IPC: C12Q1/6886
Filed: 2018-02-22
Abstract: Настоящее изобретение охватывает 2-[(3R)-3-метилморфолин-4-ил]-4-(1-метил-1H-пиразол-5-ил)-8-(1H-пиразол-5-ил)-1,7-нафтиридин (в дальнейшем называется "соединение A"), ингибитор ATR киназы, для применения в способе лечения гиперпролиферативного заболевания у субъекта. Предпочтительно гиперпролиферативное заболевание или субъект характеризуется одним или несколькими биомаркерами, выбранными из а) одной или нескольких функциональных мутаций в одном или нескольких генах/белках, выбранных из APC, ATG5, ARID1A, ATM, ATR, ATRIP, ATRX, BAP1, BARD1, BLM, BRAF, BRCA1, BRCA2, BRIP1, CCND1, CCNE1, CCNE2, CDC7, CDK12, CHEK1, CHEK2, DCLRE1A, DCLRE1B, DCLRE1C, DYRK1A, EGFR, ERBB2, ERBB3, ERCC2, ERCC3, ERCC4, ERCC5, FAM175A, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, FBXO18, FBXW7, FEN1, GEN1, HDAC2, H2AFX, HRAS, KRAS, LIG4, MDC1, MLH1, MLH3, MRE11A, MSH2, MSH3, MSH6, MYC, NBN, NRAS, PALB2, PARP1, PARP2, PARP3, PARP4, PCNA, PIK3CA, PMS2, POLA1, POLB, POLH, POLL, POLN, POLQ, PRKDC, PTEN, RAD9A, RAD17, RAD18, RAD50, RAD51, RAD52, RAD54B, RAD54L, RB1, REV3L, RPA1, RPA2, SLX4, TDP1, TDP2, TMPRSS2, TMPRSS2-ERG, TOPBP1, TOP2A, TOP2B, TP53, TP53BP1, TRRAP, UBE2N, UIMC1, USP1, WDR48, WRN, XPA, XRCC1, XRCC2, XRCC3, XRCC4 и/или XRCC6 гена/белка; и/или б) активации ALT пути; и/или в) микросателлитной нестабильности. Настоящее изобретение также охватывает набор, содержащий соединение A совместно со средствами для обнаружения одного или нескольких вышеуказанных биомаркеров и способ идентификации субъекта, имеющего гиперпролиферативное заболевание, склонное к положительной реакции на соединение A, где способ включает обнаружение одного или нескольких вышеуказанных биомаркеров. Кроме того, изобретение охватывает способ определения, будет ли субъект, имеющий гиперпролиферативное заболевание, отвечать на лечение с применением соединения A, где способ включает обнаружение одного или нескольких вышеуказанных биомаркеров в образце, полученном от субъекта.
Patent EA-202090116-A1 (EA)
Title: Композиции, содержащие конъюгаты каннабиноидного аналога, и способы применения
IPC: C07D231/10
Filed: 2018-07-18
Abstract: Настоящее изобретение относится к композициям, содержащим конъюгат метки, комплексообразователя и каннабиноидного аналога, и способам диагностики, лечения или мониторинга развития рака или неврологического расстройства, применяя данные композиции. Настоящее изобретение также относится к способам получения данных композиций и наборам для доставки данных композиций в качестве терапевтических агентов и агентов для визуализации.
Patent EA-202191928-A1 (EA)
Title: Ингибиторы дигидрооротатдегидрогеназы
Filed: 2020-01-10
Abstract: Описаны соединения, композиции и способы лечения заболеваний, расстройств или медицинских состояний, подверженных влиянию модуляции DHODH. Такие соединения представлены следующей формулой (I):где R1a, R1b, R2 и R3 определены в настоящем документе.
Patent ES-2165311-A1 (ES)
Title: Plate for wedging bottles of wine in box includes six cells separated by partitions, and with central cells with molded points
Inventor: MASSIP LAURENT
IPC: B65D81/133
Filed: 2000-02-28
Abstract: Plate (1) is inserted in box (C) that can receive up to six bottles of wine (B). Plate has six cells (2a, 2b) separated from each other by partitions (3). Some partitions have circular holes at top to allow air to flow freely. Central cells each have two molded points (5) on bottom of cells, and projection towards bottom of plate. An Independent claim is also included for the description of box where bottles of wine can be stocked.
Patent ES-2239863-A1 (ES)
Title: CFB with controllable in-bed heat exchanger
Inventor: MARYAMCHIK MIKHAIL
IPC: F22B31/00
Filed: 2002-07-15
Abstract: A circulating fluidized bed (CFB) boiler has one or more bubbling fluidized bed enclosures containing heating surfaces and located within a lower portion of the CFB boiler to provide a compact, efficient design with a reduced footprint area. The heating surfaces are provided within the bubbling fluidized bed located above a CFB grid and/or in a moving packed bed below the CFB grid inside the lower portion of the CFB boiler. Solids in the bubbling fluidized bed are maintained in a slow bubbling fluidized bed state by separately controlled fluidization gas supplies. Separately controlled fluidization gas is used to control bed level in the bubbling fluidized beds or to control the throughput of solids through the bubbling fluidized beds. Solids ejected from the bubbling fluidized beds can be returned directly into the surrounding CFB environment of the CFB boiler, or purged from the system for disposal or recycle back into the CFB. Solids which are recycled back to the CFB have less heat and can be used to control the temperature of the fast moving bed in the CFB.
Patent ES-2208119-A1 (ES)
Title: Protector for safety rails
Inventor: HINOJOSA LUCIANO
IPC: E01F15/04
Filed: 2002-11-28
Abstract: The safety protector is provided for application on vertical posts (6) tied-down to the ground and that constitute corrugated sheet supports with safety rail barrier functions, establishing a separation between its lower edge and the ground, through which a person involved in an accident due to sliding over the asphalt may impact on the corresponding section of the vertical support post (6). The safety support is constituted by an extruded profile (1) that is assembled to be adapted as a cover on post (6), the latter having internal partitions (3) and re-thickened zones, as well as an internal sinuous profile to be adapted on corresponding post (6), externally providing impact areas for persons involved in accidents that reduces the violence and diminishes the impact force, efficiently damping the latter.
Patent ES-2245159-A1 (ES)
Title: Manufacturing method for laminated material bags with self-adhesion labels, by passing laminated material with associated label through guide space within fitting collar before passing laminated material into product filling process
Inventor: GRACIA CASAS-SALAT JOAQUIN
IPC: B65B61/20
Filed: 2003-02-07
Abstract: The laminated material with associated label is made to pass through a guide space within a fitting collar. The material is then induced into a product filling process through a guiding tube. The guide space has a depth set to accommodate maximum number of laminated materials with their labels. An independent claim is also included for a form-filling machine for laminated material bags with self-adhesion labels.
Patent ES-2272120-A1 (ES)
Title: Coating method for preparing commercial nutritional products involves placing lipid cover over nutritional product and subjecting lipid cover to conditions of thermal resistance
Inventor: FERNANDEZ LIZARBE MARTIN
IPC: A23P20/12
Filed: 2004-05-04
Abstract: A lipid cover is placed over a nutritional product and is subjected to conditions of thermal resistance that allow almost instantaneous solidification of the lipid cover such that a coating is produced. The nutritional product may optionally undergo heat treatment to eliminate the lipid cover and produce a pre-cooked layer on the nutritional product.
Patent ES-2255447-A1 (ES)
Title: Folding table
Inventor: MARTINEZ LEON ANGEL
IPC: A47B3/087
Filed: 2004-12-13
Abstract: The invention relates to a folding table comprising: a board which is formed by two articulated halves (2,2') which can be extended or folded in relation to one another, and a frame which is positioned beneath the board and which supports the table at the desired height off he ground. The two halves (2,2') of the board are articulated to one another by means of hinges (18) which are located at the connecting area between said two halves. The aforementioned frame comprises at least two support assemblies (4 4') which are symmetrical to the imaginary plane which is perpendicular to the plane of the extended board and which passes through the axis along which the two halves are articulated. Moreover, each support assembly comprises: two legs (5, 6 5', 6'), the upper parts (A A') of which are articulated to the corresponding half of the board, and uprights (7, 8 7', 8') having one end (B B') which is articulated to a leg and another end (C C') which is articulated to the other half of the board at a certain distance from the articulation (D) between the two halves (2 2').
Patent ES-2292287-A1 (ES)
Title: Thermal conditioner for bottles, has body with enclosure to lodge bottles and thermal unit for conditioning temperature of enclosure, which is commanded by control system with remote temperature detector to measure temperature
Inventor: MIER RUIZ JOSE MANUEL
IPC: F25D11/00
Filed: 2005-03-10
Abstract: The thermal conditioner has a body with an enclosure to lodge the bottles. A thermal unit is provided for conditioning temperature of the enclosure, which is commanded by a control system with a remote temperature detector to measure the temperature of the lodged bottles in the enclosure.
Patent ES-2282014-A1 (ES)
Title: Catalytic briquettes for reducing temperatures, comprises precursors of transition metals, where nitrogen oxides are eliminated in presence of ammonia and excess of oxygen
Inventor: LAZARO ELORRI M JESUS
IPC: B01D53/86
Filed: 2005-06-08
Abstract: The briquettes comprises precursors of transition metals, which are used for reduction of nitrogen oxides to lower the temperatures, which is 150 to 250 degree celsius. The nitrogen oxides are eliminated in the presence of ammonia and excess of oxygen. The process is also operated in the presence of sulfur dioxide. The residue left after obtaining the product is used as petroleum coke ashes, such as precursors of active phase. An independent claim is also included for a method for preparing the catalytic briquettes, which involves treatment with carbonaceous support, deposition of a catalytically active phase for obtaining the product.
Patent ES-2301308-A1 (ES)
Title: Device and method to eliminate explosive atmospheres in tanks for storage of liquid petroleum products
Inventor: MARTINEZ NAVARRETE RAFAEL
IPC: B08B9/093
Filed: 2005-11-22
Abstract: The method consists of a degasification process of the enclosure by means of introducing vaporised fluid which captures the organic fumes of the fuel precipitating them to the floor and creating a superficial barrier which prevents the new emission of these fumes until they have been removed in the cleaning process. It has application in confined storage enclosures for liquid petroleum products and similar (tanks, vaults, basements, ditches, etc.). The device for carrying out this method consists of a base plate (4) which seals the opening (2) of the tank or enclosure (3) to be degasified. It is provided with a sprayer pipe (5) with an inlet for outside air (8) and an outlet mouth (9), an inlet for water under pressure (10) in order to provoke the spraying, and a duct (6) for evacuation eliminating over-pressures during the spraying. There exists an additional duct (7) for introduction of accessories.
Patent ES-2289959-A1 (ES)
Title: System for detecting and discriminating moving objects
Inventor: HERRANZ NIEVA ANGEL
IPC: G07C1/24
Filed: 2007-04-18
Abstract: The system comprises a set of different devices, which emits a periodic signal continuously with one of the defined parameters such as frequency and amplitude. The set of devices receive signals to add information of instant of time of detection and to provide the information in a legible format to the human or to an automatic processing system.
Patent ES-2335731-A1 (ES)
Title: Moulded tray formed by separable biodegradable disposable shovels
Inventor: NOMAN SERRANO RAMON
IPC: A47K11/10
Filed: 2008-09-30
Abstract: The invention relates to a tray obtained by moulding, manufactured using biodegradable material, based on cellulose and additives, and having a series of scrapers that can be separated from one another, in which each scraper has a grip or handle, and a scraper or actuating and cleaning end, each joined to one another by an intermediate section, having a general concave configuration that allows stacking the trays or the scrapers once separated, the scrapers being used to clean those objects or devices on which organic or any other nature of waste may be deposited.
Patent ES-2352490-A1 (ES)
Title: Seabed platform which can be configured to take different measurements, with the option for remote control and for captive or free modes
Inventor: ARREDONDO DIEZ JOSE FRANCISCO
IPC: B63G8/42
Filed: 2009-02-11
Abstract: The invention relates to a platform for obtaining data, such as hydrographic profiles, using a Total Station (or others such as OGPS or KDGPS) to measure the position (coordinates and height) of the end of a pole secured thereto. At fixed heights (< 11m), depending on the objective, the platform is moved over a sedimentary, underwater or sub-aerial surface. For heights > 11m, without a pole, the platform is connected by a cable to the surface module. This platform has various uses and control modes and can carry all types of devices, environmental sensors and image sensors and transmit data to a Base Station or store same. The platform has two portions for the purpose of outlining. The first portion, which is on land, pulls the second portion, which is underwater, enabling said portion to move continuously or stopping at suitable intervals while resting on the seabed. By direct measurement relative to a known reference, the height and position of the end of the mobile portion are obtained for every point, said end being kept in visual contact. Applying the transfer function using the height and the slope, the X, Y and Z coordinates of the seabed are obtained, as well as the depth, with an accuracy of up to 1cm. Said points provide surface profiles. The profiles are integrated to achieve the goal of the study: a morphological description of the environment. The mobile element comprises a tripod and a pole (with an IR reflector). After extensive technological development, said elements have been provided with the hydrodynamic and weight characteristics required for optimum functionality, such as single-person handling, easy assembly, speed of more than 1 m/s in water and not being affected by waves. The core of the tripod comprises two central horizontal plates, the first one of which is triangular and joined by a tube, or similar element, to the second plate occupying a lower position. Three tubes emerge radially from the first plate and curve until vertical, resting on another three horizontal straight tubes anchored to the second plate, maintaining the structural rigidity thereof by a perimeter cable. The tripod includes a set of mini-plates at the bottom ends of the vertical tubes, with other basal plates attached thereto, shaped like skates or mini-skis to enable the platform to slide across the surface of the seabed. The basal plates can be replaced with two or three cylindrical wheels, and can be optionally motorised. Each basal plate or wheel includes elements that enable calibration of the length and inclination thereof. Control can take place remotely, on-site or both remotely and on-site.
Patent ES-2351644-A1 (ES)
Title: Enzymatic method for obtaining alpha-glycosylated derivatives of resveratrol having surfactant properties
Inventor: TORRES SALAS PAMELA
IPC: C07H15/203
Filed: 2009-04-03
Abstract: The present invention is intended for use in the chemical industry and relates to a new enzymatic method for obtaining alpha-glycoside derivatives of resveratrol, in which a cyclodextrin glycosyltransferase (CGTase) is used, said CGTase originating from bacteria selected from the genuses Thermoanaerobacter and Bacillus.
Patent RS-20191690-A1 (RS)
Title: Combination of natural oils and bee venom of apitoxin
Inventor: KRIVOKAPIĆ ALEKSANDAR
IPC: A61K47/44
Filed: 2019-12-27
Abstract: The combination of natural vegetable oils and bee venom Apitoxin, consists of cold-pressed natural vegetable oils in combination with a certain amount of active substance bee venom Apitoxin obtained by the technique of collecting bee venom using the patent "Electrostimulating collector of bee venom on beehives with bees".
Patent SG-116495-A1 (SG)
Title: Recording liquid container and ink jet recording apparatus.
Inventor: NOBUYUKI HATASA
IPC: B41J29/00
Filed: 2003-04-09
Abstract: A recording liquid container for (101) containing liquid for recording to be supplied to recording means, said recording liquid container being detachably mountable to a mounting portion of a recording device, said recording liquid container includes an information memory medium (135) storing predetermined information; and wireless sending means (136) which is capable of sending the predetermined information stored in said information memory medium within a predetermined limited range. <IMAGE>
Patent SG-120280-A1 (SG)
Title: Method and trench wall cutting device for making atrench wall in the soil
Inventor: ARZBERGER MAXIMILIAN
IPC: E02D19/16
Filed: 2005-08-19
Abstract: The method involves lowering a trench wall cutter (10) with a rotatably driven cutting wheel into soil (3), wherein soil material located below the cutting wheel is stripped and a cut trench (1) is formed, and supplying a settable liquid into the cut trench. A gas e.g. air is supplied into the cut trench in a defined manner. An independent claim is also included for a trench wall cutting device.
Patent SG-127794-A1 (SG)
Title: Service initiation and regeneration control using impedance ratios
Inventor: PREMATHILAKE KUMUDIKA
Filed: 2006-04-25
Abstract: An apparatus and method for determining the end of a service step and the duration of a brine/slow rinse step in a water conditioner having a bed of ion-exchange material. A sensor probe and a reference probe are positioned in the bed of ion-exchange material vertically displaced from each other. Voltage from each of the probes are monitored over a plurality of time intervals. When the percent increase in the impedance ratio exceeds a pre- specified value the end of a service step is identified and a regeneration cycle is initiated. During the regeneration step, the rate of change in the impedance ratio of the sensor probe to the reference probe is calculated and used to detect two peaks in the rate of change of impedance ratio between the sensor probe and the reference probe, followed by terminating the brine/slow rinse step after both peaks have been detected.
Patent TR-200301160-A1 (TR)
Title: Baskı yaygı diyafram mekanizmalı piston.
Inventor: YAYKAN BILAL
IPC: F02F5/00
Filed: 2003-07-21
Abstract: Motor pistonları üzerinde bulunan,sekmanların daralıp genişlemesini sağlayan, geliştirilmiş baskı yaygı diyaframlı mekanizma. Bu yeni sistemde mevcutmotor bloğuna yeni icat edilen piston mekanizmaması monte edilmektedir. Yeni icat piston mekanizması (BYD) silindir içerisinde yakılan akaryakıt güceçevrilmesinde kullanılan piston mekanizmasıdır. Motor çalışma anında piston üst ölü noktadan alt ölü noktaya hareketi ile iş esnasında piston ve silindir arasında minimum boşluk olması ile maksimum güç elde edilmektedir. pistonun alt ölü noktaya hareket etmek istediği an yani ateş lavının maksimum olduğu an yeni sistem piston mekanizması üzerindeki mukavemet kapağına (1) basınç yapar. Bu basınç ayar plakası ile ayarlanmış (3) kurt ağızlı toplamakam pimleri hareketi sağlar. sağlanan bu hareket ile ay sekmanlarımız (8) kurt ağızlı baskı yaygı kam pimi diyafram yatağı (9) vasıtası ile genişlemeyapar. Genişleyen ay sekmanlar (8), piston (4) vesilindir arasında sızdırmazlık sağlar. Bu maksimum@
Patent TR-202021835-A1 (TR)
Title: Çalişan performansinin yöneti̇mi̇ne i̇li̇şki̇n mobi̇l haberleşme si̇stemi̇ yöntemi̇
Inventor: GÖZDE AYDIN
IPC: G06Q10/10
Filed: 2020-12-26
Abstract: Buluş, operasyonel verimliliğin artışını sağlamak üzere taşımacıların motivasyonunun arttırılmasına yönelik bir sistem ve buna ilişkin bir yöntemle ilgilidir. Daha spesifik olarak mevcut buluş, taşımacıların performansını arttırmak üzere oyunlaştırma mekaniğini taşımacılık sektörü özelinde ele alarak taşımacı profili ve eğilimleri doğrultusunda ortaya konan, taşımacılık sektörüne uygun bir sistem ve yöntemle ilgilidir.
Patent AR-022626-A1 (AR)
Title: Destapador para botellas de sidra, champagne y otras con tapones de plastico.
Filed: 2000-02-18
Abstract: Una chapa que tiene incluida: una una para levantar la punta del precinto que retiene al tapon, una ranura para trabar y desprender el precinto, unahorquilla para levantar y sacar el tapon y un tope que lo retiene para que no salga disparado.
Patent AR-025438-A1 (AR)
Title: Procedimiento para estabilizar taludes, terraplenes o diques
Inventor: DIMITER ALEXIEW
IPC: E02D17/20
Filed: 2000-08-29
Abstract: Procedimiento para estabilizar taludes (6), terraplenes (1) o diques, particularmente aquellos sobre cuya coronacion se ha construído una vía decomunicacion (2), en el cual después de cálculos y ensayos de la línea circular de rotura de talud o biende la línea de deslizamiento (4) o bien de las líneascirculares de rotura de talud oo líneas de deslizamiento (4,5) se introduce en la zona a estabilizar del talud (6) bajo elángulo más favorable cintas de anclaje (10) de alta resistencia alatraccio n con el auxilio de una lanza (8) de manera que las cintas de anclaje (10) intersecten a la línea circular de rotura de talud (4) o bien líneascirculares de rotura de talud (4) y habiéndose previsto en el extremo delantero de las cintasde anclaje respectivos anclas (11) que se anclan en el subsuelomás firme y siendo los extremos opuestos de las cintas de anclaje (10) vinculados con elementos de distribucion de carga, los cuales asientan sobre el talud(6) como ser placas, barras,rieles o rebo rdes de refuerzo.
Patent AR-026203-A1 (AR)
Title: Un conjunto de armazon y soporte de suspension combinado para un vehiculo
IPC: B60G11/16
Filed: 2000-10-20
Abstract: Un conjunto de soporte para soportar tanto un brazo de control superior y un mecanismo de suspension de resorte en un montaje de carrocería y chasisvehicular incluye una primera pieza de montaje que presenta generalmente forma de U, que incluye una p orcion central y un par de porciones lateralesenfrentadas. La porcion central de la primera pieza de montaje presenta un borde inferior que se extiende generalmente longitudinalmente y preferentementepresenta una forma tal que corresponde con la form a de una superficie superior de un larguero lateral del montaje de chasis de vehículo. Las porcioneslaterales de la primera pieza de montaje se extienden generalmente perpendicularmente relativas a la porcion central. El conjunto de soporte incluye a demás unasegunda pieza de montaje que presenta generalmente forma de taza invertida, que incluye una porcion central interna, un par de porciones laterales enfrentadasy una porcion central externa. La porcion central interna de la segunda pieza de mo ntaje presenta una forma y tamano tales para extenderse adyacente a laporcion central de la primera pieza de montaje. Porciones de las primeras y segundas piezas de montaje se sueldan unas a otras para formar el ocnjunto desoporte. Una vez armado, la primera porcion lateral de la primera pieza de montaje se extiende generalmente paralela a la porcion lateral de la segunda piezade montaje, y la segunda porcion lateral de la primer pieza de montaje se extiende generalmente paralela a la segunda po rcion lateral de la segunda pieza demontaje. Estos dos pares de porciones laterales forman dos estructuras de soprte para soportar pivotalmente los extremos del brazo de control superior. Laestructura en forma de taza invertida de la segunda pieza de montaje provee una estructura para recibir y retener positivamente el extremo superior delmecanismo de resorte de suspension en la misma.