baber/WOPTO huggingface dataset:
Patent AU-2021200118-B2 (AU)
Title: Altering gene expression in modified t cells and uses thereof
Inventor: ZHAO YANGBING
IPC: C12N15/87
Filed: 2021-01-11
Granted: 2023-09-21
Abstract: The present invention relates to compositions and methods for generating a modified T cell with a nucleic 
acid capable of downregulating endogenous gene expression selected from the group consisting of TCR a 
chain, TCR Pchain, beta-2 microglobulin and FAS further comprising a nucleic acid encoding a modified T 
cell receptor (TCR) comprising affinity for a surface antigen on a target cell or an electroporated nucleic acid 
encoding a chimeric antigen receptor (CAR). Also included are methods and pharmaceutical compositions 
comprising the modified T cell for adoptive therapy and treating a condition, such as an autoimmune 
disease.
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Patent AU-2021203636-B2 (AU)
Title: Activity and workout updates
Inventor: WILLIAMS ALED HYWEL
IPC: A63B24/00
Filed: 2021-06-03
Granted: 2022-04-28
Abstract: The present disclosure generally relates to navigating, viewing, and sharing activity and 
workout data and interacting with workout and/or activity applications. In some examples, 
scrolling of activity data is based on the content being displayed. In some examples, friends' 
activity data may be viewed. In some examples, a notification and workout data for a 
friend's completed workout is received and displayed. In some example, the activity data 
received from friends is viewed and managed. In some examples, workout data for a multi
segment workout is displayed in a three-dimensional stack on a map. In some examples, a 
workout application operates in a limited mode until a touch input is received with a 
characteristic intensity that is greater than a threshold intensity.
Patent AU-2021232812-B2 (AU)
Title: Gel compositions and methods of preparation and use thereof
Inventor: HOLLYER MATTHEW B
IPC: A61K9/00
Filed: 2021-09-17
Granted: 2023-03-02
Abstract: Compositions, e.g., gels, useful for tissue resection procedures, medical devices 
comprising the compositions, and related methods of preparing the compositions are 
discussed. The composition may comprise gellan gum, two or more salts, and water. In 
some aspects, the composition may be prepared by combining gellan gum and water to form 
a pre-mixture, heating the pre-mixture, adding two or more salts to the heated pre-mixture to 
form a mixture, introducing the mixture into a reservoir, and allowing the mixture to form a 
gel inside the reservoir. The gel may have a continuous, three-dimensional structure, and 
have desired gel strength and viscosity. The composition may be biocompatible and 
injectable from the reservoir through a needle to the target site of a patient.
Patent AU-2022202572-B2 (AU)
Title: Spa structural support assembly
Inventor: TULETT NATHAN
IPC: E04H4/14
Filed: 2022-04-19
Granted: 2023-12-14
Abstract: OF THE DISCLOSURE 
A system for supporting the structure of a spa may include vertical supports, channel 
brackets that mate with vertical supports, and exterior brackets that mate with the channel 
brackets to hold spa exterior panels in place. The vertical supports may be formed of a first 
portion and a second portion, the first portion and second portion formed of contiguous hexagons 
having one open side. The first portion may be open on a first side, with the second portion open 
on a second side. The open sides of the hexagons may create a space or pocket to allow for 
additional structures, such as brackets, to mate with the hexagons of the vertical support. A 
channel bracket may include a hexagonal boss to mate with a vertical support, as well as a 
channel for receiving a projection of an exterior bracket to hold a spa side panel in place.
Patent AU-2022228093-B2 (AU)
Title: Scheduling for positioning reference signal (prs) in narrowband-internet of things (nb-iot)
Inventor: RICO ALVARINO ALBERTO
IPC: H04L5/00
Filed: 2022-09-05
Granted: 2023-09-14
Abstract: Wireless communications systems and methods related to communicating positioning 
reference signals (PRSs) for narrowband communication are provided. A first wireless 
communication device determines a time-frequency PRS pattern based at least in part on a 
narrowband communication frequency band configuration and a PRS subframe configuration 
mode associated with a set of subframes. The first wireless communication device 
communicates, with a second wireless communication device, a plurality of PRSs using the 
determined PRS time-frequency pattern in the set of subframes. The PRS subframe 
configuration mode can indicate a first configuration including a bitmap indicating a set of 
PRS subframes positioned within a group of contiguous subframes, a second configuration 
indicating a subset of the group of contiguous subframes that may carry the PRSs, or a 
combination thereof. The first configuration and/or the second configuration can be used to 
indicate the set of subframes.
Patent AU-2023201843-B2 (AU)
Title: User interfaces for managing an account
Inventor: VAN OS MARCEL
IPC: G06F16/24
Filed: 2023-03-24
Granted: 2023-10-19
Abstract: In some embodiments, exemplary user interfaces for provisioning an electronic device with an 
account are described. In some embodiments, exemplary user interfaces for providing usage 
information of an account are described. In some embodiments, exemplary user interfaces for 
providing visual feedback on a representation of an account are described. In some 
embodiments, exemplary user interfaces for managing the tracking of a category are described.  
In some embodiments, exemplary user interfaces for managing a transfer of items are described.  
In some embodiments, exemplary user interfaces for managing an authentication credential 
connected with an account are described. In some embodiments, exemplary user interfaces for 
activating a physical account object are described. In some embodiments, exemplary user 
interfaces for managing balance transfers are described.
Patent JP-3396655-B2 (JP)
IPC: H02J7/02
Filed: 2000-02-29
Granted: 2003-04-14
Abstract: A bicycle power supply circuit (27) is provided whereby an AC voltage from an AC generator (19) mounted on a bicycle is converted to a DC voltage, and the converted DC voltage is provided to an electrical component on the bicycle. The bicycle power supply circuit (27) includes a first input terminal (40) for connecting to a first AC generator output terminal of the AC generator, a second input terminal (41) for connecting to a second AC generator output terminal of the AC generator, a first output terminal (40) for connecting to the electrical component, and a second output terminal (41) for connecting to the electrical component. A full-wave voltage rectifier circuit (42) converts AC voltage presented at the first and second input terminals (40,41) into a DC voltage, and a storage device is coupled to the voltage rectifier (42), wherein the storage device has a positive voltage terminal and a negative voltage terminal. The positive voltage terminal is coupled for providing a positive voltage signal to the first output terminal (40) and the negative voltage terminal is coupled for providing a negative voltage signal to the second output terminal (41). <IMAGE>
Patent JP-3202014-B2 (JP)
IPC: F28D15/02
Filed: 2000-06-01
Granted: 2001-08-27
Abstract: A cooling device having a high cooling efficiency in a miniature size that is neither influenced by gravity nor restricted in its position of installation. The device exchanges, transports and dissipates heat generated by a heat source. The device includes a coolant storing part for storing liquid coolant, a heat absorbing part including at least one micro channel, the heat absorbing part is closely positioned to the heat generating source and connected to the coolant storing part. The liquid coolant is partly filled in the micro channel by surface tension and vaporized to become a gaseous coolant in the micro channel when heat is absorbed from the heat generating source. The device includes a heat insulating part positioned adjacent to the heat absorbing part to prevent the heat absorbed by the heat absorbing part from transferring to other zones. The device includes a condensing part for condensing the gaseous coolant. The condensing part is positioned apart from the heat absorbing part. The device includes a gas moving part positioned near the heat absorbing part and the condensing part, and the gas moving part includes a passage through which the gaseous coolant moves from the heat absorbing part to the condensing part. The device further includes a housing in which at least the heat absorbing part is housed.
Patent JP-4832627-B2 (JP)
IPC: H04W28/06
Filed: 2000-08-25
Granted: 2011-12-07
Abstract: A base station assembles a frame including information bits at a vocoding rate for downlink transmission over a traffic channel as channel bits at a channel rate. The base station places at least one rate-indicating bit at a beginning of the frame for indicating the vocoding rate. The mobile station evaluates the downlink transmission with consideration of the vocoding rate indicated by the at least one rate-indicating bit. The mobile station can determine the vocoding rate by decoding the beginning of the frame to permit power control in less than one frame duration from initial receipt of the frame at the mobile station. <IMAGE>
Patent JP-4357102-B2 (JP)
IPC: G04G21/00
Filed: 2000-08-25
Granted: 2009-11-04
Abstract: A watch (1) has hour and minute hands (8,10) and a watch glass (4). In addition a matrix of tactile sensors (16) is supported by the watch glass and is used to control a computer cursor through radio or infrared channels. The movement of a finger across the tactile sensors is interpreted in direction by a least squares technique and the cursor is moved correspondingly and at a proportional speed. A button (14) provides the clicking facility
Patent JP-3594544-B2 (JP)
IPC: F25D11/00
Filed: 2000-09-27
Granted: 2004-12-02
Abstract: PROBLEM TO BE SOLVED: To solve the problems that conventionally a vegetable container has to be constituted small because of shallow depth thereof in a refrigerator having a fresh food storage compartment, a vegetable compartment and a frozen food storage compartment arranged in this order from above, having a cold air circulation fan and a damping part provided in a rear face part of the fresh food storage compartment, and having a cooler vertically arranged from the rear face part of the frozen food storage compartment to the rear face part of the vegetable compartment, and that the structure becomes complex, because another blower for air curtain and an air duct are required in case the air curtain is formed in the front face opening of the fresh food storage compartment. SOLUTION: A fresh food storage compartment cooler is provided in a cooler chamber in the rear face upper part of the fresh food storage compartment, and a cold air circulation blower for a fresh food storage compartment is provided above the same. A cold air distribution duct for distributing cold air cooled by the cooler to the fresh food storage compartment comprises an upper face duct, provided on an upper face part of the fresh food storage compartment for blowing the cold air downward to the front face opening of the fresh food storage compartment and rear face ducts, provided vertically on left and right sides of the cooler chamber for supplying the cold air from the rear face of the fresh food storage compartment to the fresh food storage compartment. A return duct to the cooler chamber is disposed between the left and right rear face ducts below the cooler chamber.
Patent JP-4291512-B2 (JP)
IPC: C08F8/22
Filed: 1999-03-18
Granted: 2009-07-08
Abstract: Blocky chlorinated polyolefins are disclosed as compatibilizers of PVC and/or CPVC resins with polyolefin elastomers. The blocky chlorinated polyolefins facilitate the dispersion of the elastomers as a dispersed phase with the proper size for impact modification of the PVC and/or CPVC. The blocky chlorinated polyolefin provides better adhesion between the elastomer and the PVC and/or CPVC providing better physical properties such as impact strength as measured by Notched Izod and variable height impact testing (VHIT) than did the randomly chlorinated polyolefins, often used as processing aids and as impact modifiers in PVC or CPVC. The differences in properties achieved with blocky chlorinated polyolefins versus randomly chlorinated polyolefins are attributed to the individual blocks of the blocky polyolefin being compatible (and/or co-crystalizable) with either the polyolefin elastomer or the PVC/CPVC resulting in better adhesion between phases.
Patent JP-4601168-B2 (JP)
IPC: A61P31/16
Filed: 1999-07-29
Granted: 2010-12-22
Abstract: Microparticles with adsorbent surfaces, methods of making such microparticles, and uses thereof, are disclosed. The microparticles comprise a polymer, such as a poly( ALPHA -hydroxy acid), a polyhydroxy butyric acid, a polycaprolactone, a polyorthoester, a polyanhydride, and the like, and are formed using cationic, anionic, or nonionic detergents. The surface of the microparticles efficiently adsorb biologically active macromolecules, such as DNA, polypeptides, antigens, and adjuvants.
Patent JP-3902728-B2 (JP)
IPC: C12N15/12
Filed: 1999-09-22
Granted: 2007-04-11
Abstract: The present invention provides fusion polypeptides that bind to and traps Interleukin-4 (IL-4), thus acting as am IL-4 antagonist. It also provides nucleic acid sequences that encode the fusion polypeptides, and methods of making them and uses for them.
Patent JP-4435985-B2 (JP)
IPC: C12N5/02
Filed: 1999-11-04
Granted: 2010-03-24
Abstract: The method for obtaining and expanding TcRgammadelta+ T cells in culture is described. The method involves: 1) culturing cells from a sample containing TcRgammadelta+ T cells or precursors thereof in a first culture medium comprising a T cell mitogen and at least two cytokines and 2) culturing the cells obtained in step 1) in a second culture medium comprising at least two cytolines. Preferably, the method comprises 1) culturing the cells in a first culture medium comprising (a) a T cell mitogen, (b) interleukin-2 and (c) interleukin-4, and 2) culturing the cells obtained in step 1) in a second culture medium comprising (i) interleukin-2 and (ii) interleukin-4 to obtain TcRgammadelta+ T cells. The TcRgammadelta+ T cells obtained by the method can be used in a variety of experimental, therapeutic and commercial applications.
Patent JP-4637367-B2 (JP)
IPC: A61K47/38
Filed: 2000-03-22
Granted: 2011-02-23
Abstract: A granulate is described containing granules of an active ingredient endowed with therapeutic/nutritional activity coated with a granulating/bonding agent, suitable for conversion into a solid administration form with a very high content of active ingredient, particularly in the form of tablets obtained by means of a direct compression procedure, or suitable for constituting the content of capsules.
Patent JP-3844657-B2 (JP)
IPC: C07D493/10
Filed: 2000-04-12
Granted: 2006-11-15
Abstract: The present invention provides a novel class of 4,5-diaryl-3(2H)-furanone derivatives, which inhibit strongly and selectively COX-2 over COX-1. They are useful to treat inflammation, inflammation-associated disorders, and COX-2 mediated diseases.
Patent JP-5342727-B2 (JP)
IPC: A61K8/92
Filed: 2001-03-16
Granted: 2013-11-13
Abstract: PROBLEM TO BE SOLVED: To provide a deodorizing composition effective for masking tobacco smell among various foul smells, especially the smell of mainstream smoke of tobacco released to the environment by smoking, especially provide a deodorizing composition capable of masking foul smell without intensifying the odor of the whole perfumery to an undesirable level in the case of mixing to a formulated flavor or producing other undesirable smell caused by the mixing to the formulated flavor. SOLUTION: The perfumery composition for eliminating tobacco smell is composed of a combination of three or more groups selected from the compounds of groups (A), (B), (C) and (D) and essential oils of the group (E). (A) An aliphatic aldehyde compound having aldehydic aroma or green aroma, (B) an aldehyde compound containing benzene ring and having fruity aroma or green aroma, (C) a ketone compound having fruity aroma or green aroma, (D) an aliphatic ester compound having fruity aroma or green aroma and (E) essential oils having green aroma, balsamic aroma, fruity aroma, amber aroma or spicy aroma.
Patent JP-3568914-B2 (JP)
IPC: C12P17/10
Filed: 2001-04-19
Granted: 2004-09-22
Abstract: The optically active compounds of formula I are useful for the preparation of optically active 3-aminopyrrolidine derivatives which are important building blocks for the production of useful products in the chemical, agricultural and in the pharmaceutical industry. In particular they are useful in the production of antibacterial substances for example of vinylpyrrolidinone-cephalosporin derivatives. The process may also be used for the preparation of N-protected L-asparagine by work up of the remaining aqueous layer. The present invention relates to a new process for the preparation of D-asparagine derivatives of formula I <CHEM> wherein R<1> is an amino protecting group and R<2> is an alkyl, a substituted alkyl or a group of formula A R<3)<OCH2CH2)n-   A wherein R<3> is hydrogen or an lower alkyl group and n is 1, 2 or 3.,  which process comprises reacting a compound of formula II <CHEM>     wherein R<1> and R<2> are as defined above, with a protease in an aqueous system at a pH of 6.0-7.5, preferably 6.0-7.0, together with an organic co-solvent and subsequent extraction of the enantiomeric pure product of formula I.
Patent JP-4004260-B2 (JP)
IPC: B65G49/06
Filed: 2001-09-26
Granted: 2007-11-07
Abstract: PROBLEM TO BE SOLVED: To make compact a substrate processing system while reducing the cost by delivering a substrate using a single carrying arm even when a plurality of types of containing section or processing section having different type of substrate holding structure exist. SOLUTION: A substrate cleaning system 1 comprises cassettes C1-C4 for containing not yet processed substrates W and processed substrates W, a unit SS1 for cleaning the surface of the substrate W, and a unit SS2 for cleaning the rear surface of the substrate W. The carrying arm 45 of a carrying robot TR delivers the substrate W with respect to the cassette C and further delivers the substrate W with respect to the cleaning units SS1 and SS2. The carrying arm 45 has a plan view not interfering with the substrate holding face of the cassetes C and the cleaning units SS1 and SS2.
Patent JP-3581847-B2 (JP)
IPC: B26B13/24
Filed: 2001-10-29
Granted: 2004-10-27
Abstract: The pair of hairdressing scissors has connecting blocks (40) mounted in the through holes (12,22) of the handles (11,21) of the scissors (1). The dovetail blocks (43,45) of the connecting blocks are connected to the dovetail grooves (41) of the connecting blocks of another pair of scissors to mutually connect the pairs of the scissors.
Patent JP-3566949-B2 (JP)
IPC: C08F110/02
Filed: 1999-10-23
Granted: 2004-09-15
Abstract: The present invention relates to a catalyst for homo-polymerization or co-polymerization of ethylene, or more particularly to a solid complex titanium catalyst for homo-polymerization or co-polymerization of ethylene. The catalyst may be produced by preparing a magnesium solution by contact-reacting a magnesium halide compound with an alcohol. Reacting the solution with an ester compound and a boron compound. Then reacting the solution with a mixture of a titanium compound and a silicon compound.
Patent JP-4763951-B2 (JP)
IPC: G04B33/08
Filed: 2000-08-31
Granted: 2011-08-31
Abstract: The invention concerns a timepiece with mainspring of the so-called fly tourbillon type, the tourbillon having a balance bridge ( 2 ) forming a cage with a collet ( 1 ) and a single protruding ball bearing ( 5 ) supporting said so-called fly tourbillon assembly. Said so-called fly tourbillon assembly is visible on the dial side ( 15 ) and is designed as an independent tourbillon module. Said tourbillon module is separable from the clockwork ( 13 ) by being detached on the rear side of the clockwork ( 13 ) and by being removed on that same side.
Patent JP-4955171-B2 (JP)
IPC: C07D213/68
Filed: 2000-11-16
Granted: 2012-06-20
Abstract: Disclosed are novel aromatic compounds of the formula (I) wherein G, X, Ar, L and Q are defined herein. The compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are processes of making such compounds
Patent JP-4357148-B2 (JP)
IPC: A61B17/16
Filed: 2001-04-06
Granted: 2009-11-04
Abstract: A surgical drill guide assembly for demountable attachment to a slotted bone plate is provided. The drill guide assembly includes one or more alignment drill tubes that are remotely aligned with corresponding fastener holes in the bone plate, and an expandable bushing that is configured and dimensioned to engage a slot in the bone plate. A variable angle block permits angulation of the alignment drill tubes about a central axis of the surgical drill guide assembly. The alignment drill tubes are releasably lockable at a surgeon-selected angle.
Patent JP-4818562-B2 (JP)
IPC: H04N7/173
Filed: 2002-02-18
Granted: 2011-11-16
Abstract: A system and process for providing progressively higher quality versions of an audio and/or video program over a client-server based network. In response to a user command to view a particular program, the client requests layered data associated with the program from the server. The client also specifies how many consecutive layers are to be transmitted based on the bandwidth available on the network. The client then receives the data from the server, caches it, renders it as it is received, and presents it to the viewer. Upon a request from the user for a higher quality version of the program, the client requests as many enhancement layers associated with the program as possible given the available bandwidth. The client receives the requested data, combines it with the previously stored lower-level layer data, renders the higher quality version of the program, and presents the new version to the user. <IMAGE>
Patent JP-4234951-B2 (JP)
IPC: G01K1/02
Filed: 2002-05-29
Granted: 2009-03-04
Abstract: An electrical charge is stored on a floating grid (8) which is separated from the other plate (10) of the capacitor by an insulating layer (12). A temperature operated contact (2) which may be bimetallic or alternatively a capsule containing a mixture of water and alcohol closes when a reference temperature is exceeded allowing the stored charge to leak to a charge flow circuit (18). The loss of charge is measured by a conduction change in a semiconductor (6) An Independent claim is also included for a method of monitoring temperature by implanting a stored charge and then detecting any subsequent absence of charge
Patent JP-4061531-B2 (JP)
IPC: C08F290/06
Filed: 2002-05-31
Granted: 2008-03-19
Abstract: <P>PROBLEM TO BE SOLVED: To provide an active ray-curing polyimide resin composition having heat resistance, capable of patterning with an aqueous dilution alkaline solution and soluble in organic solvents.  <P>SOLUTION: The active ray-curing polyimide resin composition comprises (I) a polymerizable polyimide resin and, if necessary, (II) an organic solvent, (III) an epoxy resin and (IV) a photopolymerization initiator, wherein the polymerizable polyimide resin contains an isocyanurate ring, a cyclic aliphatic structure, an imide ring and a (meth)acryloyl group and allows of patterning with an aqueous dilution alkaline solution, preferably the isocyanurate ring having a concentration of 0.4-1.2 mmol/g, the (meth)acryloyl group having a concentration of 0.3-4 mmol/g, the polyimide resin having an acid value of 20-250, a number-average molecular weight of 1,000-20,000 and a weight-average molecular weight of 1,500-30,000.  <P>COPYRIGHT: (C)2003,JPO