baber/WOPTO huggingface dataset:
Patent AT-E318301-T1 (AT)
Inventor: BRUESTLE OLIVER PROF DR
IPC: C12N15/09
Filed: 1998-12-18
Granted: 2006-03-15
Abstract: A process for producing neuronal or glial progenitor cells, comprising: (a) culturing embryonic stem cells to form embryoid bodies; (b) culturing the embryoid bodies to form neural progenitor cells; (c) proliferating the neural progenitor cells in a serum-free medium containing growth factor(s); (d) further proliferating the neural progenitor cells in a serum-free medium containing growth factor(s) and isolating the neural progenitor cells; and (e) further proliferating the neural progenitor cells in a serum-free medium containing growth factor(s) and isolating the neural progenitor cells. Independent claims are included for the following: (1) a process for producing glial progenitor cells, comprising: (a) culturing embryonic stem cells to form embryoid bodies; (b) culturing the embryoid bodies to form neural progenitor cells; (c) proliferating the neural progenitor cells in a serum-free medium containing growth factor(s); (d) further proliferating the neural progenitor cells in a serum-free medium containing growth factor(s) form spheroids with neuronal and glial differentiation potential; and (e) proliferating the spheroids in a serum-free medium containing growth factor(s) until a lawn of glial progenitor cells is formed, and isolating the cells; (2) neuronal or glial progenitor cells that are produced as above and include no more than 15% of primitive embryonic cells and non-neural cells; and (3) a cell library comprising autologous and nonautologous cells as above.
Patent AT-E261092-T1 (AT)
Inventor: RIESSELMANN FRANZ-JOSEF
IPC: E04F15/02
Filed: 1999-03-25
Granted: 2004-03-15
Abstract: An insulating element, e.g., for laying floor heating pipes, comprises a plate (12) made of a heat and/or sound damping material, and a layer (18) on the plate which contains projections (20) for holding the pipes (32). The layer comprises a foamed plastic material and the projections are hollow.
Patent AT-E223310-T1 (AT)
Inventor: MUTH CHRISTOPHER
IPC: B41F13/16
Filed: 1999-07-24
Granted: 2002-09-15
Abstract: The current supply uses a current souce (3), e.g. a battery, contained within the printing machine cylinder (1) and a switch (2) for coupling the current source to an electrical load (4), which is released automatically when the printing cylinder is stationary in dependence on its position. The switch may use an electrically conductive fluid (8) contained within a tube (7), for providing an electrical contact path between a pair of switch contacts (5,6) in a given position of the printing cylinder.
Patent AT-E256781-T1 (AT)
Inventor: BUBIK ALFRED DR
IPC: D21F1/02
Filed: 1999-09-22
Granted: 2004-01-15
Abstract: The stock inlet for a papermaking machine, with a pulp feed and a turbulence generator, has a path section (I) where the free cross section steadily decreases towards the outlet which is directly followed by a second path section (II) with a steady and continuous expansion to the outlet.  The second path section (II) with a flow expansion can be followed by a third path section with a steady and decreasing free flow cross section. The third path section length L3 is shorter than the second (II) length L2, which is shorter than the length L1 of the first path section (I). The structure of the path lengths is expressed as L2<0.3> L3 L2<0.7> and L1<0.1> L2 L1<0.3>. The first path section (I) starts directly after the turbulence generator. The total crosssection of the stock inlet jet is formed by a single suspension flow channel (4) at least over part of the length of the stock inlet jet. Or a number of suspension flow channels are over at least part of the stock inlet jet length of the total cross section of the stock inlet jet, formed by at least one divider between the two limit walls. Without exception, all the suspension flow channels have the same cross section pattern, in a shape which covers each other. The rate of divergence at the second path section (II) is identical for all the suspension flow channels. The dividers form a point towards each other at the second path section (II), each with the same degree of convergence at the ends of their surfaces. The alignment of the upper (1) and/or lower (2) wall of the stock inlet, at least in the second path section (II), is in a mirror image to the line of the adjacent divider in relation to the surfaces in contact with the suspension flow. The turbulence generator has a number of diffusion tubes, arranged in rows across the machine width. The dividers start between the rows of diffusion tubes. The upper and lower walls of the stock inlet have the same length. The ratio of the change in the reducing cross section height in the flow direction to the flow path length in the first path section (I) is 0.3-40.0 % and preferably 10-30%. The ratio of the increasing cross section height in the flow direction to the flow path length in the second path section (II) is 0.1-20.0% and preferably 2-12%. The ratio of the change in the reducing crosssection height in the flow direction to the flow path length in the third path section is 1-400% and preferably 10-200%. The first path section (I) has a length of 250-1000 mm and preferably 400-800 mm. The second path section (II) has a length of 20-150 mm. The length of the third path section is 0.5-300.0 mm and preferably 1-100 mm. The smallest cross section height of the first path section (I) is 10-500 mm, and preferably 15-150 mm, and 30-200 mm at the second path section (II), and 5-80 mm in the third path section.
Patent AT-E235997-T1 (AT)
Inventor: GOTTSCHALK GERD
IPC: B26D5/00
Filed: 1999-10-05
Granted: 2003-04-15
Abstract: A machine for cutting stacked sheets of stock. The machine has a counter for accommodating the stock. The rear of the counter accommodates the stock to be cut and the front of the counter the cut stock. The rear of the counter also accommodates a mechanism for advancing the stack and a baffle for one side of the stack to rest against. A bent is positioned above the counter and accommodates a blade for cutting the stock and a holdfast that can be lowered onto the top of the stack. A control panel and a display panel are positioned on the front side. The machine in accordance with the present invention is characterized by at least one camera (22) at the rear (9) of the counter. The camera monitors the position of the stock in relation to the stack-advancing mechanism (10) or the lateral baffle (12) and displays on the display panel (17) a real-time image (26) of what it can discern. The operator can accordingly indirectly but precisely monitor the position of the stock in relation to the stack-advancing device or to the lateral baffle or both but only when that position needs correcting.
Patent AT-E278166-T1 (AT)
Inventor: ROTTMANN DIETRICH
IPC: F25J3/04
Filed: 1999-11-05
Granted: 2004-10-15
Abstract: The oxygen-free pressurized nitrogen fraction is released into the low pressure column which is heated in its sump. In the low pressure column, raising vapors form and by means of a cycle ultrapure nitrogen from carbon monoxide is released at the top of the low pressure column, carbon monoxide-free head-gas is removed at the top of the low pressure column and partially liquefied at raised pressure. The liquefied portion is released in He-Ne-He-column which is heated in its sump, and the ultrapure nitrogen is removed as liquid. The oxygen-free pressurized nitrogen fraction is drawn either from an upper portion of the pressure column liquid or ready in a liquid tank with stored oxygen-free nitrogen. Process for producing ultrapure nitrogen is by means of low temperature analysis of air in a rectifying system having a rectifying column where compressed; passing purified air into a pressure column from which oxygen-free nitrogen pressure fraction is produced; passing the fraction into a low pressure column and producing as head gas carbon monoxide free low pressure nitrogen in the low pressure column.
Patent AT-E482446-T1 (AT)
Inventor: ROSENBERG LOUIS
IPC: G01C21/36
Filed: 1999-03-24
Granted: 2010-10-15
Abstract: A knob controller device comprises: 
a knob coupled to a grounded surface, said knob rotatable in a rotary degree of freedom about an axis extending through said knob, said knob also moveable in one or more of:- 
¢ a transverse direction approximately perpendicular to said axis; 
¢ a linear degree of freedom approximately parallel to said axis;  
a rotational sensor that detects a position of said knob in said rotary degree of freedom; 
one or more of:- 
¢ a transverse sensor operative to detect a position of said knob in said transverse direction; 
¢ a linear sensor operative to detect a position of said knob in said linear degree of freedom;  
and 
an actuator coupled to said knob and operative to output a force in said rotary degree of freedom about said axis.
Patent AT-E494848-T1 (AT)
Inventor: MIKUS PAUL
IPC: A61B18/02
Filed: 1999-03-30
Granted: 2011-01-15
Abstract: A cryoprobe system with a vented high pressure gas supply line. Venting of the gas supply line upon cut-off of high pressure gas quickens the warming process of the cryoprobe.
Patent AT-E243892-T1 (AT)
Inventor: ANDERSKOUV NIELS
IPC: H03F1/56
Filed: 1999-05-11
Granted: 2003-07-15
Abstract: A method and apparatus of measuring current in a switching circuit (2) of the two-port type having a first set of terminals connected to a set of terminals of a noise reducing circuit, wherein a second set of terminals of the switching circuit has a switching terminal, which is adapted to be switched between the set of terminals of the noise reducing circuit, including the steps of providing an impedance in parallel with the switching circuit; measuring a current as a transient measurement during switching sequences in the switching circuit, the measurement being performed across an impedance in the noise reducing circuit.
Patent AT-E418105-T1 (AT)
Inventor: JONKER WILLEM
IPC: G06F17/30
Filed: 1999-04-09
Granted: 2009-01-15
Abstract: A network server for adapting reference data, such as URL links, comprising at least a port (11) for connection to a communication network (1), which is communicatively connected to at least a client terminal (20) and to at least a second server (30), a memory (16) with a memory section for storage of reference data, reception means (12) for receiving messages via the port (11) and transmission means (13) for transmitting messages, in which in the memory (16) a reference data (18) to page information (39) present in the at least one second server (30) is stored, in which the network server (10) furthermore is equipped for transmitting the reference data (18) via the port (11) from the memory (16) to the client terminal (20), characterised in that the network server (10) furthermore is equipped for receiving page information (39) belonging to the reference data (19) from the memory (36) of the second server (30) via the port (11) of the client terminal (20), and in that the network server (10) is provided with adaptation means (14) which have been equipped for adapting the reference data (18) in the memory (16) on the basis of a status indicator (37) included in the received page information (39).
Patent AT-E300922-T1 (AT)
Inventor: JANSEN PETER
IPC: A61F2/16
Filed: 1999-05-03
Granted: 2005-08-15
Abstract: Intraocular lens comprising a central optical body and haptics attached to or formed integrally with said optical body wherein the haptics are attached to the optical body via connecting members separating the haptic plane from the optical plane by a distance b which is at least half the thickness of the optical body.
Patent AT-E209595-T1 (AT)
Inventor: HALL OLA
IPC: B65G5/00
Filed: 1999-02-15
Granted: 2001-12-15
Abstract: The invention relates to a method in operating a lined cavern provided for the storage of gas coming from a pipeline. During filling of the cavern with gas to a nominal pressure, at least a portion of the gas is withdrawn from the cavern and recirculated to the cavern under cooling and without substantial compression. The method also includes recirculating the gas under heating and without substantial compression.
Patent AT-E266424-T1 (AT)
Inventor: GREENWALD RICHARD B
IPC: C07D213/64
Filed: 1999-07-12
Granted: 2004-05-15
Abstract: The present invention is directed to double prodrugs containing polymeric-based transport forms. These polymeric prodrugs are preferably of the formula:wherein:B is H, OH, OSiR13, a residue of an amine-containing target moiety or a residue of a hydroxyl-containing target moiety,G isor CH2;Y1-2 are independently O or S;M is X or Q; where X is an electron withdrawing group and Q is a moiety containing a free electron pair positioned three to six atoms from C(=Y2);R1, R4, R7, R8, R9, R10 and R13 are independently one of hydrogen, C1-6 alkyls, C3-12 branched alkyls, C3-8, cycloalkyls, C1-6 substituted alkyls, C3-8 substituted cycloalkyls, aryls, substituted aryls, aralkyls, C1-6 heteroalkyls, substituted C1-6 heteroalkyls, C1-6 alkoxy, phenoxy, C1-6 heteroalkoxy, except that R1 and R4 can also be a cyano, nitro, carboxyl, acyl, substituted acyl, carboxyalkyl;Ar is a moiety which when included in Formula (I) forms a multi-substituted aromatic hydrocarbon or a multi-substituted heterocyclic group;(m) is zero or one;(n) is zero or a positive integer;(p) is zero, one or two;(q) is three or four; andR11 is a substantially non-antigenic polymer.
Patent AT-E331791-T1 (AT)
Inventor: LOUGHNEY KATE
IPC: G01N33/50
Filed: 1999-02-23
Granted: 2006-07-15
Abstract: The present invention provides novel human PDE10 polypeptides, polynucleotides encoding the polypeptides, expression constructs comprising the polynucleotides, host cells transformed with the expression constructs; methods for producing PDE10 polypeptides; antisense polynucleotides; and antibodies specifically immunoreactive with the PDE10 polypeptides. The invention further provides methods to identify binding partners of PDE 10, and more particularly, binding partners that modulate PDE10 enzyme activity.
Patent AT-E256696-T1 (AT)
Inventor: PIGNOT MARC
IPC: C12N9/10
Filed: 1999-07-28
Granted: 2004-01-15
Abstract: Aziridine derivatives of formula (I)are disclosed which can be used as cofactor for S-adenosyl-L-methionine-dependent methyltransferases.
Patent AT-E234345-T1 (AT)
Inventor: ERKENS LEONARDUS JOHANNES HUBE
IPC: C08K3/24
Filed: 1999-09-22
Granted: 2003-03-15
Abstract: Zirconium-containing, red-tinged bismuth vanadate pigments of general formula I,wherein the variables have the following meanings:b 0.8 to 1.5;c 0 to 0.3;d 0 to 0.3;e 0.01 to 0.3;f 0 to 0.3;x (3/2+5b/2);y (2e+2 f);z 0.001 to 0.5, and a process for the preparation thereof and the use thereof in pigmenting high molecular weight organic materials such as surface-coatings, plastics and printing inks.
Patent AT-E269059-T1 (AT)
Inventor: EINIG HEINZ
IPC: A61K9/36
Filed: 1999-12-14
Granted: 2004-07-15
Abstract: A pharmaceutical mixture comprising a profen is described which has a profen content of over 85 % and contains up to 1% of a nonionic surfactant having an HLB of >/=9 and also a customary disintegrant and a lubricant and optionally a microcrystalline cellulose.
Patent DE-10723213-T1 (DE)
Title: Hebegerät für einen mäher mit extern montiertem heber
Inventor: BUSSON RÉMY
IPC: B66F7/28
Filed: 2010-04-06
Abstract: Vorrichtung zum seitlichen Kippen (10) einer Rasenmähmaschine, insbesondere eines Aufsitzrasenmähers (11), umfassend ein festes Rahmenelement (12), das dazu bestimmt ist, auf dem Boden aufzuliegen, und ein Rahmenelement (14), das geeignet ist, mindestens ein Rad der Maschine aufzunehmen, das um eine Achse (13), die von dem festen Rahmenelement (12) getragen ist, zwischen einer Verstaustellung, in der sich das bewegliche Rahmenelement (14) im Wesentlichen in der Ebene erstreckt, die durch das feste Rahmenelement (12) gebildet ist, und mindestens einer angehobenen Stellung, in der das bewegliche Rahmenelement (14) von dem festen Rahmenelement (12) beabstandet ist, beweglich ist, dadurch gekennzeichnet, dass sie, wobei das bewegliche Rahmenelement (14) einen Rahmen aufweist, der ein Gestell (141) bildet, der konfiguriert ist, um das Rad oder die Räder aufzunehmen, einen Zylinder (24) aufweist, der einen Körper (241), der mit dem festen Rahmenelement (12) fest verbunden ist, und eine Stange (242) aufweist, die in Bezug auf den Körper beweglich ist, die mit dem beweglichen Rahmenelement (14) an dem Rahmen (141) fest verbunden ist, der derart befestigt ist, um sich im Wesentlichen außerhalb des Bereichs (15) zu erstrecken, der durch das feste (12) und bewegliche (14) Rahmenelement in der angehobenen Stellung begrenzt ist.
Patent DE-21794984-T1 (DE)
Title: Verfahren zur Empfängnisverhütung mit Nomegestrolacetat und Estradiol
Inventor: BOOLELL MITRA
IPC: A61K31/575
Filed: 2021-10-12
Abstract: Verfahren zur Kontrazeption, umfassend:(i) Identifizieren einer Frau, die Kontrazeption wünscht, die geeignet ist für den Erhalt eines kombinierten hormonellen Kontrazeptivums (CHC);(ii) Auswählen eines CHC, wobei das ausgewählte CHC als ein CHC identifiziert wurde, das mit geringstem VTE-Risiko assoziiert ist, wobei das ausgewählte CHC eine kombinierte orale kontrazeptive (COC) Zusammensetzung ist, die Nomegestrolacetat und Estradiol oder einen Ester davon umfasst; und(iii) Bereitstellen des ausgewählten CHC, das mit geringstem VTE-Risiko assoziiert ist, zur Verabreichung an die Frau, die Kontrazeption wünscht.
Patent DE-286453-T1 (DE)
IPC: A01N33/12
Filed: 1988-04-11
Abstract: A biocidal composition for the treatment of water comprises a cationic polyquaternary ammonium biocide, e.g. an ionene halide, or a quaternary ammonium biocide or a quaternary ammonium biocide comprising a long chain alkyl group and three other groups selected from lower alkyl and aralkyl groups, together with a source of transition metal cations e.g. copper II cations and/or a biocide of the type containing a gem. bromonitromethylene group e.g. 2- bromo-2-nitropropane-1,3-diol.
Patent DE-810032-T1 (DE)
Inventor: GREEN ROGER RICHARD
IPC: B04B1/20
Filed: 1997-05-22
Abstract: A decanter centrifuge for separating a feed suspension of particulate solid material in a liquid medium into a light fraction comprising a suspension of relatively light particles in the liquid medium and a heavy fraction comprising a suspension of relatively heavy particles in the liquid medium, which centrifuge comprises an elongated bowl (1,2) having a first closed end, a second closed end and a side wall between the ends, the bowl being mounted for rotation within, and coaxially with the bowl, driving means for rotating the bowl and the scroll (3) about their common axis whereby the scroll and the bowl can be rotated with different rotational speeds, means (8,9,10) for delivering feed suspension into the bowl in a delivery region inside the bowl, a plurality of first outlets (11) provided in the wall of the bowl for discharging the heavy fraction from the bowl and one or more second outlets (12) provided at or near to the first end of the bowl for discharging the light fraction from the bowl and wherein the delivery region is nearer to the second end of the bowl than to the first end of the bowl and the first outlets are located close to the delivery region. The centrifuge is particularly suitable for concentrating an aqueous suspension of an inorganic particulate mineral material or for separating such a material into heavy and light fractions, eg. to produce a finer fraction product. Such a material may be one of the known materials useful as inorganic pigment, filler or extender materials, eg. kaolin, metakaolin, calcium carbonate, calcium sulphate and the like. <IMAGE>
Patent ES-2128283-T1 (ES)
Title: Profarmacos de inhibidores de trombina.
Inventor: ANTONSSON THOMAS
IPC: C07K5/065
Filed: 1996-12-17
Abstract: SE DESCRIBEN UNOS COMPUESTOS CON LA FORMULA (I): R 1 O(O)C CH 2 (R)CGL AZE PAB R 2 , EN LA QUE R 1 Y R 2 POSEEN LOS SIGNIFICADOS CONTENIDOS EN LA DESCRIPCION, QUE SON UTILES COMO PROFARMACOS DE LOS INHIBIDORES DE LAS PROTEASAS PARECIDAS A LA TRIPSINA, COMO LA TROMBINA, Y, EN PARTICULAR, EN EL TRATAMIENTO DE AQUELLAS CONDICIONES DONDE SE REQUIERA LA INHIBICION DE LA TROMBINA (P.EJ. TROMBOSIS) O COMO ANTICOAGULANTES.
Patent CY-1107630-T1 (CY)
Inventor: BAKER CARL J
IPC: A61K31/485
Filed: 2007-05-17
Abstract: The present invention relates to a transdermal delivery device disposal system for disposing of a transdermal delivery device containing at least one pharmaceutically active component. The disposal system contains at least one sheet or substrate on which an adhesive is coated; and one or more of the following components: (a) monomer, and optionally comonomer(s), to be polymerized; (b) an initiator, and optionally co-initiator(s), to initiate the polymerization; (c) at least one crosslinking agent to crosslink the (co)polymer; and (d) at least one deactivating agent to chemically alter, to degrade, and/or to deactivate the active component(s) contained in the transdermal delivery device, such as an opioid antagonist or an opioid agonist deactivating agent so that the euphoric effects of the active component(s) contained in the transdermal delivery device are at least temporarily inhibited, diminished, or halted  in vivo , wherein at least one adhesive-coated sheet or substrate adheres to, immobilizes, or isolates, and prevents, inhibits, or diminishes the misuse or abuse of the active component contained in, at least one transdermal delivery device.
Patent CY-1108297-T1 (CY)
Inventor: DESHPANDE RAJENDRA V
IPC: A61P43/00
Filed: 2008-08-26
Abstract: Selective binding agents of osteoprotegerin binding protein (OPGbp) are provided by the invention. More particularly, the invention provides for antibodies and antigen binding domains which selectively bind to OPGbp and may be used to prevent or treat conditions relating to loss of bone mass. Nucleic acid molecules encoding said antibodies and antigen binding domains, and expression vectors and host cells for the production of same are also provided.
Patent CY-1109019-T1 (CY)
Inventor: BOMBARDELLI EZIO
IPC: A61P21/00
Filed: 2009-05-05
Abstract: The present invention relates to colchicine derivatives, in particular to the 3-demethyl and 3-demethylthio-colchicine of the general formula (I) in which X is oxygen or sulfur, a method for the preparation thereof and pharmaceutical compositions containing them. The compounds of formula (I) have muscle relaxing, anti-inflammatory and anti-gout activity.
Patent CY-1109464-T1 (CY)
Inventor: AL-MAHMOOD SALMAN
IPC: A61P19/02
Filed: 2009-10-07
Abstract: Angiogenesis-modifying composition (A) containing at least one of a nucleic acid (I) from the gene encoding IRS-1 (insulin receptor substrate-1), or its complement or fragments, or a molecule (II) that inhibits expression of the nucleic acid, is new. ACTIVITY : Ophthalmological; Antiarthritic; Antirheumatic; Antiinflammatory; Gynecological; Antipsoriatic; Cytostatic; Vasotropic; Hypotensive; Vulnerary; Antianginal; Cardiant; Osteopathic. Corneal wounds were made in rats as described in Invest. Ophthalmol. Vis. Sci., 39 (1998) 18, then the animals given a subconjunctival injection of a composition containing 60 MicroM of the oligonucleotide (3), antisense to the IRS-1 gene 5'-TATCCGGAGGGCTCGCCATGCTGCT (3) in buffered saline, every day from days 4 to 9. The animals were killed on day 10 and the degree of neovascularization determined by staining with fluorescein-dextran, photography under a fluorescent microscope and then the ratio of neovascularized surface to total corneal surface was calculated. This ratio was 0.6157 (n = 15) for treated animals, compared with 0.9552 (n = 9) for those injected with saline only and 0.9170 (n = 9) for untreated animals, indicating a statistically significant reduction in neovascularization caused by (3). Similar results were obtained by topical application of an ointment containing 200 MicroM (3). MECHANISM OF ACTION : Antisense gene therapy.