baber/WOPTO huggingface dataset:
Patent NZ-238557-A (NZ)
Title: N-substituted (5-phenyl (and -naphthyl)(methyl)dioxan-2-yl alkyl)amine, amide and carbamate derivatives; preparatory processes and pharmaceutical compositions
Inventor: RAIZON BERNARD
IPC: A61P25/24
Filed: 1991-06-14
Abstract: A compound which is a 2-aminoalkyl-5-arylalkyl-1,3-dioxane of general formula (I)   <IMAGE> (I)  in which m represents 0 or 1; n represents 1, 2, 3 or 4; R1 represents hydrogen or methyl; R2 represents hydrogen, methyl or an alkanoyl group of the general formula COR' in which R' represents a hydrogen atom or a linear or branched C1-C4-alkyl group, or an alkoxycarbonyl group of the general formula COOR'' in which R'' represents a linear or branched C1-C4-alkyl group; and Ar represents either a phenyl group optionally carrying one or two substituents selected from halogen, C1-C4 alkyl, methoxy and trifluoromethyl, or a naphthalen-1-yl or naphthalen-2-yl group optionally carrying a substituent selected from halogen, methyl, methoxy and cyclopropylmethoxy groups, in the form of a cis- or trans-stereoisomer, and in the form of a free base or an acid addition salt thereof and its therapeutic use.
Patent NZ-243707-A (NZ)
Title: Preparation of n, n'-asymmetrically substituted phenylureas. (51)
Inventor: HACKL KURT ALFRED
IPC: A01N47/00
Filed: 1992-07-24
Abstract: Process for the preparation of very pure ureas of the formula phenyl-(NH-CO-NR1R2)n in which phenyl represents an unsubstituted or substituted phenyl or phenylene group and R1 and R2 are either identical and each represent an alkyl group, or are different, in which case R1 represents a hydrogen atom and R2 represents an alkyl or phenyl group, or R1 and R2, together with the nitrogen atom, represent an aliphatic heterocyclic ring and n is the number 1 or 2, by reacting a phenylurea of the formula phenyl-(NH-CO-NH2)n with an amine of the formula NR1R2H at temperatures from 100 to 200 degrees C. in a diluent which is inert under the reaction conditions, the reaction being interrupted before by-products are formed, and the urea which is formed being removed from the starting compounds, and the unreacted starting compounds being returned to the process if appropriate.
Patent NZ-244585-A (NZ)
Title: 9-substituted-amino tetracycline derivatives and pharmaceutical compositions
Inventor: HLAVKA JOSEPH J
IPC: C07D277/22
Filed: 1992-10-01
Abstract: Novel 7-substituted-9-(substituted amino)-6-demethyl-6-deoxytetracycline compounds having activity against a wide spectrum of organisms including organisms which are resistant to tetracyclines are disclosed. Also disclosed are intermediates and methods for making the novel compounds of the present invention.
Patent NZ-250300-A (NZ)
Title: Asymmetric pyrrolidine derivatives
Inventor: HAGEN SUSAN ELIZABETH
IPC: C07D207/08
Filed: 1993-11-26
Abstract: Optically pure isomers of 7-(3-(1,1-dialkylmethyl-1-amino)-1-pyrrolidinyl)quinolones and naphthyridones as therapeutically active and safe antibacterial agents are described, as well as pharmaceutical compositions thereof, and a method of treating bacterial infections therewith. Also described is a method of manufacture of the quinolones and naphthyridones as well as the starting materials, the optically pure pyrrolidine moieties for attachment at the 7-position.
Patent NZ-272527-A (NZ)
Title: Pharmaceutical composition comprising ligand(s) selective for rxr receptors and ligand(s) selective for rar-alpha receptors
Inventor: MICHEL SERGE
IPC: A61P35/02
Filed: 1995-07-07
Abstract: Compsn. comprises a ligand with selectivity for a hetero-dimerised retinoic acid receptors (RXR) and ≥ 1 second ligand with selectivity for the  alpha -retinoic acid receptor ( alpha -RAR), in a physiologically acceptable support.
Patent NZ-275100-A (NZ)
Title: Tetracyclic oxepine derivatives and medicaments
Inventor: FRIEBE WALTER-GUNAR
IPC: C07D313/12
Filed: 1994-10-22
Abstract: PCT No. PCT/EP94/03479 Sec. 371 Date Sep. 10, 1996 Sec. 102(e) Date Sep. 10, 1996 PCT Filed Oct. 22, 1994 PCT Pub. No. WO95/11906 PCT Pub. Date May 4, 1995Compounds of formula I    <IMAGE>  (I)  in which Q denotes hydrogen, a hydroxy group or a C1 to C8 alkoxy group which can be substituted if desired, by carboxyl or C1 to C6 alkoxycarbonyl and either Y and Z together form a group   <IMAGE>   and X represents hydrogen, C1 to C6 alkyl or C2 to C6 alkenyl or Y and X together form a group   <IMAGE>Z represents hydrogen, C1 to C6 alkyl or C1 to C6 alkanoyl, where R denotes hydrogen or a C1 to C6 alkyl residue as well as physiologically tolerated salts thereof, processes for their production and pharmaceutical agents containing these compounds for the treatment of inflammatory diseases and allergic diseases.
Patent NZ-285122-A (NZ)
Title: Stable, concentrated medicament containing docetaxel (or derivatives), at least 1 unsaturated phospholipid and small amount of at least 1 negative phospholipid
Inventor: DURR MANFRED
IPC: A61K31/425
Filed: 1995-04-24
Abstract: This invention relates to a pharmaceutical composition comprising as active principle, docetaxel or a taxoid derived from docetaxel, one or more unsaturated phospholipids and a small amount of one or more negative phospholipids, allow the active principle to be formulated in high concentration and are suitable for administration by injection.
Patent NZ-323869-A (NZ)
Title: Method and apparatus for forming piles in-situ
Inventor: VICKARS ROBERT ALFRED
IPC: E02D5/46
Filed: 1996-12-20
Abstract: his method is for making piles and apparatus for use in this method. The method  may be used to support the foundation of a structure, such as a building.  The method draws soil displacing means (60) on a shaft (39) down through a body of soil (46) by turning a screw (34) at the lower end of the shaft.  The soil displacing means forces soil out of a cylindrical region (74) around the shaft.  The cylindrical region is filled with grout (70) which encapsulates and strengthens the shaft.  The grout may be fed by gravity from a bath of grout around the shaft.  The soil displacement means has a diameter smaller than a diameter of the screw and may be a disk extending in a plane generally perpendicular to the shaft.
Patent NZ-328040-A (NZ)
Title: Aerobic fermentation system with travelling fermentation promoting apparatus, overhead excrement supply nozzles and openable roof curtains
Inventor: KIM BAIK KI
IPC: C05F17/02
Filed: 1995-01-14
Abstract: PCT No. PCT/KR95/00005 Sec. 371 Date Oct. 3, 1996 Sec. 102(e) Date Oct. 3, 1996 PCT Filed Jan. 14, 1995 PCT Pub. No. WO95/21141 PCT Pub. Date Aug. 10, 1995An aerobic fermentation promoting device, a fermentation system and organic compost prepared by the system. The device promotes aerobic fermentation of compost materials by periodically mixing the compost materials together and by letting the compost materials come into contact with the outside air. The device is installed in a fermentation tank and has a rotatable screw conveyor unit, at least one bucket elevator, a drive unit and a steering unit. The compost is produced by charging moisture control materials in the tank, uniformly spraying excrement on the surface of the moisture control materials, mixing the compost materials together using the fermentation promoting device after lapse of four to seven days since spraying of the excrement, and adding new moisture control materials and new excrement to existing compost materials.
Patent NZ-334302-A (NZ)
Title: Ultrasonic therapeutic treatment using low and high frequencies together
Inventor: YOUNG MICHAEL JOHN RADLEY
IPC: A61B8/08
Filed: 1997-08-18
Abstract: The method and apparatus of the application is directed to treating skeleto/muscular injuries or of diagnosing bone fractures and comprises: Applying to an external surface of the tissue a two component source of energy, each component having a different frequency in the range between 10 kHz and 4 MHz. This may be done by applying to an external surface of overlying tissue an application head and transmitting therethrough an ultrasonic wave comprising a low frequency carrier wave onto which is superimposed a high frequency transmission. Alternatively the method may comprise steps of applying to an external surface of the tissue an application head which comprises a first member capable of emitting energy at a comparatively low frequency, optionally in the region of between 10 and 110 kHz and applying also energy generated by a second piezo electric source at a frequency in the region of 0.5 to 3 MHz.
Patent NZ-335903-A (NZ)
Title: Anti-proliferative radiolabelled DNA oligonucleotide, preparation and use for controlling uncontrolled cell proliferation
Inventor: LECLERC GUY
IPC: A61P9/00
Filed: 1997-11-26
Abstract: An anti-proliferative substance for preventing uncontrolled cellular proliferation such as cancer or malignant tumors.  It comprises a radiolabeled DNA carrier comprising a DNA sequence selected from the group consisting of:  		CAC GTT GA*G GGG CAT 		ATG CCC C*TC AAC GTG 		GCC CGA* GAA CAT CAT 		CCT CGC* AGT TTC CAT	(* indicates the position of the radioisotope)  A radioisotope is located internally within the DNA sequence at any position between nucleotides 4 and 12.  The radiolabeled DNA carrier penetrates a cell membrane and is retained intracellularly for a time sufficient for the radioisotope to effect an efficient dose therapy.
Patent NZ-502979-A (NZ)
Title: Milk composition to make calcium to magnesium with high solubility made by using ultrafiltration and nanofiltration techniques
Inventor: KOTANI MASANORI
IPC: A23L2/52
Filed: 2000-02-22
Abstract: A milk mineral composition obtained from milk and a method for producing the same. The milk mineral composition contained the components in the ratio of 0.48 ³ log {(amount of calcium in composition)/(amount of magnesium in composition)} and -0.30 [ log {amount of calcium in composition)/(amount of sodium in composition)}. The method was further characterised in that the permeate was obtained by filtering milk with an ultra-filtration (UF) membrane and further filtered with nano-filtration (NF) membrane to remove monovalent minerals and concentrated to remove lactose by crystallization, after which the resulting liquid is concentrated and/or dried. The resulting milk mineral composition has a calcium-magnesium ratio and high solubility and can thus be added to drinks or food products for mineral fortification.
Patent NZ-510563-A (NZ)
Title: Multiple unit controlled food effect-independent release pharmaceutical preparations and method for preparing the same
Inventor: RUPP ROLAND
IPC: A61K9/16
Filed: 1999-09-17
Abstract: Process for the production of an orally administrable multiple-unit sustained release dose formulation having controlled agitation-independent release, characterised in that the hydrophilic polymer HPC, having an average molecular weight of 250 000 to 1 200 000, is combined in an amount from 40-95% by weight, based on the active compound-polymer mixture and a molar degree of substitution of at least 3, as a release-sustaining erosion material, with at least one pharmaceutically active compound.  This active compound-polymer combination is converted into small particles having a diameter of 0.2-3.0 mm and these are used in the production of active oral administration forms and medicaments.
Patent NZ-516814-A (NZ)
Title: Image data analysis of objects
Inventor: MALMSTROM KURT
IPC: G01N21/25
Filed: 2000-07-10
Abstract: A method is disclosed for analysing colour image data relating to a target object, particularly an animal carcase, to derive or predict a property of the object of which colour is an indicator, such as meat yield. The method includes the step of processing the colour data to derive "intensity normalised" or light intensity independent measures of colour values, followed by the step of calculating the property of the object utilising the light intensity independent colour measures in a predictive equation in which the light intensity independent colour measures are variables and the property of the object is calculated from solving the predictive equation. The predictive equation can be developed from data gathered during a data gathering experiment using images captured for real target objects, and correlating the light intensity independent colour measures obtained from these data with the actual measured property of each of the real target objects to derive the predictive equation by statistical analysis techniques to best fit the data. For meat carcase analysis, the property predicted can be the "yield", "conformation", or "fat score" of a carcase in a standard carcase grading system, or can be the "yield grade" or "quality grade" of meat from a carcase in a standard meat grading system.
Patent NZ-520032-A (NZ)
Title: Crystalline salts of 7-[4-(4-fluorophenyl)-6-isopropyl- 2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5- dihydroxyhept-6-enoic acid and pharmaceuticals and uses thereof
Inventor: TAYLOR NIGEL PHILIP
IPC: A61P9/10
Filed: 2001-02-12
Abstract: A crystalline salt of the compound (E)-7-[4-(4- fluorophenyl)6-isopropyl-2- [methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5- dihydroxyhept-6-enoic acid, wherein the salt is an ammonium, methylammonium, ethylammonium, diethanolammonium, tris(hydroxymethyl)methylammonium, benzylammonium, 4- methoxybenzylammonium, lithium or magnesium salt.
Patent NZ-520977-A (NZ)
Title: Acoustic sounding
Inventor: MARTIN ANDREW LOUIS
IPC: G01S15/58
Filed: 2001-03-08
Abstract: Methods and apparatus for atmospheric sounding using acoustic chirps are disclosed, the transmitted and echo chirps being compared in a mixer that yields frequency sums and differences. The mixing is performed as a complex multiplication in the Fourier domain. In one system (1) a signal generator (5) such as a PC sound card drives a loudspeaker (3) that serves as a transmitter and echo pulses are detected by a microphone (4) that serves as a receiver. Chirps transmitted by the loudspeaker (3) travel by different paths (7a and 7b) due to reflection from TILS or thermal inversion layers (2a and 2b) at different altitudes. The transmitted and echo chirp signals are compared in a mixer (6) from which various outputs (8 and 9) can be generated. One output (8) might be the magnitude of the difference between the transmitted and echo chirp tones, instant by instant, which is indicative of the altitudes of the respective TILs. The other output (9) might be the phase shift in an echo tone with transit time, which is indicative of vertical wind velocity at different altitudes. Such sounding methods and apparatus are useful for weather research, prediction of plume dispersal and the design of microwave links to minimize multipath fading.
Patent NZ-526241-A (NZ)
Title: Gyrase inhibitors and uses thereof
Inventor: GRILLOT ANN-LAURE
IPC: A61K31/00
Filed: 2001-12-12
Abstract: Compounds of the formula I: or a pharmaceutically acceptable derivative or prodrug thereof. The compounds are useful as inhibitors of bacterial gyrase activity. The present invention also relates to methods for treating bacterial infections in mammals. The present invention also relates to methods for decreasing bacterial quantity in a biological sample.
Patent NZ-529200-A (NZ)
Title: Fluid flow and level device with tethered floating and/or sinking indicators
Inventor: ASHCROFT JOHN TERENCE
IPC: G01P5/04
Filed: 2004-01-13
Abstract: The device has a fluid flow passage and at least two of the following: within the fluid flow passage a tethered floating indicator 1; within the fluid flow passage a tethered sinking indicator; the housing forming the fluid flow passage is at least partially transparent so as to enable the indicator(s) to be viewed. The term "indicator" is intended to embrace a sensor so that either of the floating or sinking indicators may be connected to a suitable indicator, for example an external indicating arm (not shown) where the fluid or housing is not sufficiently transparent.
Patent NZ-530704-A (NZ)
Title: Process for obtaining growth factor (TGF-beta and IGF-1), lactoperoxidase and immunoglobulins preparations from milk products having low mutual cross-contamination
Inventor: KIVITS MARINUS GERARDUS CORNEL
IPC: C07K14/65
Filed: 2002-07-22
Abstract: Disclosed is a process for extracting fractions containing the growth factors TGF-B and IGF-1 from a milk product, comprising the steps of: recovering a basic fraction of the milk product by means of cationic exchange chromatography; contacting a solution containing the obtained fraction with a hydrophobic interaction chromatography resin comprising a carrier and a ligand attached to the carrier; wherein the ligand of the hydrophobic interaction chromatography resin is selected from a n-butyl group, a t-butyl group, and a phenyl group; eluting the hydrophobic interaction chromatography resin with an eluent to obtain a fraction containing growth factor compounds; and wherein the eluent contains substantially no alcohol when a phenyl group is used as a ligand.
Patent NZ-535671-A (NZ)
Title: Use of thalidomide for treating cancer
Inventor: D AMATO ROBERT
IPC: A61K31/404
Filed: 1994-02-24
Abstract: Thalidomide is used in the manufacture of a medicament to treat a solid or blood borne tumour in a patient. The tumour can be breast cancer, leukaemia, bone marrow neoplastic disease, or acoustic neuroma.
Patent NZ-536404-A (NZ)
Title: An ablation catheter with sensing and ablation electrodes on respective loops
Inventor: ANDERSON NEIL LAWRENCE
IPC: A61B18/02
Filed: 2003-05-09
Abstract: An ablation catheter includes an elongate carrier including a tubular member 38, a first loop 14.1 at the distal end of the carrier, sensing electrodes 40 carried on the first loop for sensing irregular electrical activity in the patient's body, and a second loop 14.2 proximate the first loop on the carrier and in a fixed orientation with respect to the first loop. Ablating electrodes 42 are carried on the second loop for ablating a site of the patient's body where irregular electrical activity occurs. The tubular member of the elongate carrier is folded back on itself to form a distal hairpin and a pair of limbs 12 extending from the hairpin, the limbs having a pair of proximal ends. The loops are carried on the limbs and the size of each loop is adjustable by appropriate manipulation of the proximal end of at least one of the limbs.
Patent NZ-539610-A (NZ)
Title: Equipment for repairing biological tissue, such as a tendon or a ligament and, in particular, the calcanean tendon
Inventor: MARTIN JEAN-JACQUES
IPC: A61F2/08
Filed: 2003-11-05
Abstract: Equipment for repairing biological tissue, such as a tendon or a ligament and, in particular, the calcanean tendon. The equipment comprises a link (3) and elements (5) which are used to stop the link in relation to the fragments of tissue to be repaired. One of the stop elements comprises a bone screw (2) which can be implanted in a bone surrounding the tissue to be repaired, for example in the calcaneum in order to repair the calcanean tendon. The link forms a tubular part (6) in which one part of the screw can be tightly inserted along with at least two cords (4) which can be inserted through the fragments of the biological tissue to be repaired, for example the two fragments of a broken calcanean tendon. Other stop elements comprise at least two stop buttons (5).
Patent NZ-541678-A (NZ)
Title: Golf putter with rotary disc alignment aid
Inventor: SHERMAN ROBYN ANN
IPC: A63B53/04
Filed: 2004-02-12
Abstract: A putter head (1) is described wherein the putter head (1) has a putter face (4) and a linear marking (9) located on an upper surface (44) of the putter head (1). The relative angle of the putter face (4) with respect to the linear marking (9) is adjustable in order to compensate for inherent inaccuracies in a player's visual judgement when putting. In a preferred embodiment, the upper surface (44) is in the form of a rotatable disc (3) wherein the rotatable disc (3) is moveable about an axis in order to selectively adjust the relative angle between the linear marking (9) and the putter face (4).
Patent NZ-544092-A (NZ)
Title: Electro-adhesive tissue manipulator
Inventor: PALANKER DANIEL V
IPC: A61F9/007
Filed: 2004-06-18
Abstract: An electro-adhesive tissue manipulator is disclosed. The electro-adhesive tissue manipulator comprises: (a) a conducting element; (b) an electrical means capable of providing a first pulse and a second pulse to the conducting element, wherein the first pulse generates an adhesive state between the conducting element and the tissue layer strong enough to manipulate the tissue layer, and the second pulse generates a non-adhesive state to the adhered tissue layer to detach the adhered tissue layer from the conducting element; and (c) a control means to control the generation of the first pulse and the second pulse.
Patent NZ-550037-A (NZ)
Title: Antistatic paint cup comprising a reusable plastic cup holder, a lid having an opening, and a flexible, disposable see through cup positioned in the reusable cup holder
Inventor: KOSMYNA MICHAEL J
IPC: B05B7/24
Filed: 2005-05-27
Abstract: A fluid supply assembly and a method of maintaining uniformity of a coating mixture during dispensing, is disclosed. The fluid supply assembly comprises a reusable plastic cup holder, a lid having an opening, and a flexible, disposable see through cup positioned in the reusable cup holder. The disposable cup comprises a side wall, an open outlet end, and a closed bottom that defines an interior where the disposable cup collapses as the fluid is dispensed. The lid covers the open outlet end of the disposable cup. The disposable cup comprises a polymeric material containing an antistatic additive where the antistatic additive prevents chargeable particles in a coating mixture from sticking to the disposable cup so that uniformity of the coating mixture is maintained while it is dispensed.
Patent NZ-551664-A (NZ)
Title: Alkynyl derivatives as modulators of metabotropic glutamate receptors
Inventor: BESSIS ANNE-SOPHIE
IPC: A61K31/428
Filed: 2005-06-17
Abstract: The disclosure relates to pyridine derivative compounds of formula (I) wherein W, X, R15, R16, R17, R18 and R19 are as defined in the specification, these compounds are modulators of metabotropic glutamate receptors - subtype 5 ("mGluR5") which are useful for the treatment of central nervous system disorders as well as other disorders modulated by mGluR5 receptors. These compounds are particularly suitable for treating or preventing central nervous system disorders selected from the group consisting of: addiction, tolerance or dependence, affective disorders, psychiatric disease, Parkinson's disease, memory impairment, Alzheimer's disease, dementia, delirium tremens, other forms of neurodegeneration, neurotoxicity, and ischemia; for treating or preventing inflammatory or neuropathic pain; for treating or preventing behaviour disorders and dependence disorders selected from the group consisting of alcohol, nicotine, cocaine, amphetamine, benzodiazepine, analgesics, opiate or other substance tolerance or dependence, bulimia nervosa, anorexia nervosa, gambling dependence, sex dependence, or obsessive compulsive disorders; for treating or preventing schizophrenia, depression and attention-deficit/hyperactivity disorder; and such other disorders modulated by mGluR5 receptors.
Patent NZ-553662-A (NZ)
Title: Medical tube set
Inventor: SAKAI YOSUKE
Filed: 2007-03-07
Abstract: A medical tube set comprising a tube (10) and a stylet (20) that improves the insertability of tube. The stylet structure comprises an inner core (21) that can be inserted into the tube, an apical tip (22) that is affixed to the apical end of the inner core, and a movable expansion member (23) that can move between the apical tip of the inner core and a stop (24) that is provided at a predetermined distance from the apical tip. An engagement (22a) is formed at the posterior end of the apical tip, and is able to engage the apical end (11b) of tube. By positioning the movable expansion member within the apical end of the tube, the apical end can expand radially outwards so that the apical tip can pass through.