baber/WOPTO huggingface dataset:
Patent WO-2019133949-A1 (WO)
Inventor: WANG XIAO-JING
IPC: C12N15/79
Filed: 2018-12-30
Abstract: The present technology provides methods and compositions for the treatment of inflammatory and/or tissue damage conditions. In particular, the use of truncated Smad7 compositions delivered locally or systemically to a site of inflammation and/or tissue damage is described. Other specific embodiments concern treatment or prevention of side effects caused by radiation and/or chemotherapy, including but not limited to oral and gastric mucositis. Also provided are codon-optimized nucleic acids encoding for Smad7 fusion proteins.
Patent WO-2019139947-A1 (WO)
Title: Mechanisms for the adaptive control of service layer operations
Inventor: LY QUANG
IPC: H04W4/70
Filed: 2019-01-09
Abstract: Service Layer adaptation may be realized through one or more adaptation rules that are programmed by server administrators in a structured but flexible manner. As part of integrating the adaptive control into its operations, a Service Layer may be configured to provide the capability to receive requests in which an adaptation rule may be specified, to provide indications through response codes returned to requestors that the Service Layer is not able to process a request due to a reduced functional state, and to send a request for more server resources or move an application, a service, or a service instance to another platform.
Patent WO-2019143553-A1 (WO)
Title: Signal spreading techniques for non-orthogonal multiple access wireless communications
Inventor: LEI JING
IPC: H04J11/00
Filed: 2019-01-14
Abstract: Methods, systems, and devices for wireless communications are described in which different spreading sequences may be used to distinguish concurrent non-orthogonal multiple access (NOMA) transmissions. The spreading sequences may be selected based on one or more codebooks configured at a user equipment (UE) and a codebook for an uplink NOMA transmission determined based on a set of common resources allocated for the uplink NOMA transmission and a number of expected transmitters in a transmitter group. The UE may identify data to transmit in the uplink NOMA transmission, apply the spreading sequence to the data, and transmit the spread data in the uplink NOMA transmission. A base station may receive multiple concurrent uplink NOMA transmissions, perform receive signal processing to identify spreading signals and UE identity, de-spread the signals based on different spreading sequences, and demodulate and decode the de-spread signals of the NOMA UE.
Patent WO-2019147982-A1 (WO)
Inventor: KELER TIBOR
IPC: A61K38/19
Filed: 2019-01-25
Abstract: L'invention concerne des méthodes de traitement du cancer comprenant l'administration à des patients d'un agent mobilisateur de cellules dendritiques (par exemple., ligand FIt3) en combinaison avec d'agents de rayonnement et/ou immunorégulateurs (par exemple, des inhibiteurs de points de contrôle).
Patent WO-2020145997-A1 (WO)
Title: Dimensional compensations for additive manufacturing
Inventor: DIEGO GUTIERREZ VICTOR
IPC: B33Y50/02
Filed: 2019-01-31
Abstract: In an example, a method includes receiving, at at least one processor, object model data representing at least a portion of an object that is to be generated by an additive manufacturing apparatus by fusing build material within a fabrication chamber. An indication of an intended object placement location within the fabrication chamber may be determined, and a plurality of predefined locations within a fabrication chamber may be identified based on a volumetric extent of the object or object portion if placed in its intended object placement location, wherein the predefined locations are related to dimensional compensation values. A dimensional compensation value to apply to the object model data may be determined by combining the dimensional compensation values relating to the identified plurality of predefined locations and applied to the object model data to generate modified object model data.
Patent WO-2019164669-A1 (WO)
Title: Blends of polyesters and polysaccharides
Inventor: JOHNSON ROSS S
IPC: C08L67/00
Filed: 2019-02-07
Abstract: A polyester composition comprising at least one polyester selected from the group consisting of poly(trimethylene terephthalate), polyethylene terephthalate, polybutylene terephthalate, and copolymers thereof; and at least one poly alpha-1,3-glucan ester having a degree of substitution of from about 0.3 to 3 moles of at least one acyl group per repeat unit of poly alpha-1,3-glucan. Articles prepared from these polyester compositions exhibit at least one improved physical property such as heat deflection temperature, tensile strength, Young's modulus, or impact strength. Such polyester compositions may also be prepared from renewable resources.
Patent WO-2019165262-A1 (WO)
Title: Measuring eye refraction
Inventor: LUO GANG
IPC: A61B3/032
Filed: 2019-02-22
Abstract: Methods, systems, and devices are provided for measuring eye refraction without a lens, and more particularly, for measuring eye refraction with a mobile device application. An exemplary method includes measuring a distance between a patient and a mobile device, presenting to the patient one or more visual targets sized and shaped to represent perfect vision such as by using Vernier targets or grating targets, instructing the patient to indicate whether the patient can accurately read the visual targets and, if not, to move closer to the mobile device until the patient can accurately read the visual targets, calculating a vision prescription for the patient based on the visual targets and a final distance between the patient and the mobile device, and displaying the vision prescription for the patient.
Patent WO-2019182727-A1 (WO)
Inventor: SMITH CHARLES
IPC: B64C3/20
Filed: 2019-02-25
Abstract: An aircraft structural component, for example, a wing spar (36) that has an I-beam shape having upper (38) and lower spar caps (40) coupled by a web (42) therebetween and that provides structural support for an aircraft wing (14). The wing spar may be fabricated as a graphite composite that is thermally cured to have a certain stiffness. In one embodiment, the wing spar is fabricated so that the upper spar cap has a higher coefficient of thermal expansion than the web, which creates tension forces in the spar cap when the spar is thermally cured and then cooled. Therefore, when the wing spar is mounted to the wing and the aircraft is in flight, compression forces on the wing skin act to relieve the tension forces in the spar cap, which reduces the compression buckling load on the wing.
Patent WO-2019173102-A1 (WO)
Inventor: ROBINSON STEVEN
IPC: E04B1/68
Filed: 2019-02-28
Abstract: L'invention concerne un système pour créer une étanchéité joint durable entre des panneaux adjacents, notamment ceux qui peuvent être soumis à une dilatation et à une contraction thermique ou à un cisaillement mécanique, présentant une plaque de recouvrement, un rail et un noyau compressible élastiquement adjacent au rail.
Patent WO-2020009730-A1 (WO)
Title: High-number card game with specialty table surface and strategic method of betting
Inventor: COLBURN BRANDON GENE
IPC: A63F1/00
Filed: 2019-02-28
Abstract: A high-number card game with specialty table surface and method of betting requires players to pick a playing card that has a higher number than the dealer, such that the players card competes only against the dealers card, and the bigger card number wins; and if tied, the dealer wins. A card table provides a table surface defined by a card play portion for retaining the cards until displayed by the dealer; a primary bet portion where players place primary bets; and a bonus bet portion where players place bonus bets. The primary and bonus bet portions are disposed on table surface in an arcuate shape along the longitudinal direction. The primary bet portions are more proximal to the players than the bonus bet portions; and the primary bet portions are larger than the bonus bet portions, so as to encourage larger bets and minimize risk of card counting.
Patent WO-2019173417-A1 (WO)
Inventor: WANG MINGHAN
IPC: C07K16/30
Filed: 2019-03-06
Abstract: L'invention concerne des anticorps anti-TIP-1 et des fragments de liaison à l'antigène associés. L'invention concerne également des acides nucléiques codant pour les anticorps, des compositions comprenant les anticorps, et des procédés de production des anticorps et des méthodes d'utilisation des anticorps pour traiter ou prévenir des maladies telles que le cancer.
Patent WO-2019178222-A1 (WO)
Title: Corrective collar utilizing geolocation technology
Inventor: EHRMAN KENNETH SCOTT
IPC: A01K11/00
Filed: 2019-03-13
Abstract: The disclosed technology includes a pet collar that can be configured to determine its geolocational position and evaluate that position with respect to the geo-fence of a predetermined, geo-fenced "safe" zone. If the collar determines that its position is inside a safe zone but is near the geo-fence, the collar can be configured to provide a warning correction. If the collar determines that it is outside a predetermined safe zone, the collar can also be configured to provide a stronger correction to discourage the pet from continuing away from the safe zone. The collar can also be configured to guide the pet back to the safe zone such as by varying the strength and/or type of correction provided based at least in part on the distance of the collar from the geo-fence.
Patent WO-2019183425-A1 (WO)
Inventor: LEE SANG IN
IPC: C23C4/01
Filed: 2019-03-21
Abstract: A film deposition apparatus includes a body formed with openings and cavity, a spray assembly, and a gas assembly. The spray assembly sprays a precursor stream into the cavity for forming a film on a substrate. The gas assembly injects one or more gases into the cavity through the openings to shape the precursor stream and improve directionality and utilization of the precursor stream. The film deposition apparatus can operate with one or more plasma generators to form a laminated film on the substrate. The laminated film may have three layers of film: a first film formed through reaction of a first precursor with plasma, a second film being a composite of the first precursor and a second precursor, and a third film formed through sonification of the second precursor on top of the second film. The second precursor can infiltrate into the first film and fill defects therein.
Patent WO-2019204021-A1 (WO)
Title: Pcsk9 targeting oligonucleotides for treating hypercholesterolemia and related conditions
Inventor: DUDEK HENRYK
IPC: C12N15/113
Filed: 2019-04-01
Abstract: This disclosure relates to oligonucleotides, compositions and methods useful for reducing PCSK9 expression, particularly in hepatocytes. Disclosed oligonucleotides for the reduction of PCSK9 expression may be double- stranded or single- stranded, and may be modified for improved characteristics such as stronger resistance to nucleases and lower immunogenicity. Disclosed oligonucleotides for the reduction of PCSK9 expression may also include targeting ligands to target a particular cell or organ, such as the hepatocytes of the liver, and may be used to treat hypercholesterolemia, atherosclerosis, and/or one or more symptoms or complications thereof.
Patent WO-2019195221-A1 (WO)
Title: Improved devices for tissue treatment and methods of use thereof
Inventor: SHAW JONATHAN
IPC: A61B17/32
Filed: 2019-04-02
Abstract: The invention provides systems and methods for monitoring a status of targeted tissue undergoing a procedure via a medical device, such as, for example, a tenotomy, and further providing feedback associated with one or more parameters of the targeted tissue in real-time to thereby indicate a completeness of the procedure to an operator of the medical device. The invention also provides devices with a magnetic coupling of components and methods of use of such devices.
Patent WO-2019195815-A1 (WO)
Title: Aqueous humor cell-free dna and ophthalmic disease
Inventor: BERRY JESSE
IPC: C12N15/113
Filed: 2019-04-06
Abstract: Tumor-derived cell-free DNA from the aqueous humor is assayed for diagnosis, and therapeutic prognosis of retinoblastoma demonstrating eyes with a more aggressive phenotype (with the presence of gain of 6p) and those that have a higher likelihood of responding to therapy. This also allows for evaluation of tumor response to therapy and a marker of recurrent or residual disease that requires further therapy. This method avoids direct biopsy of retinoblastoma, which is contraindicated due to risk of extraocular tumor dissemination. Somatic chromosomal copy number alterations of tumor-derived cell-free DNA provides significant prognostic value; the presence of gain of 6p was associated with a 10x increased risk of a tumor NOT responding to chemotherapy with local consolidation and requiring enucleation to cure the child of disease. AH testing also provides accurate indicators of progression of retinoblastoma and its response to therapy over the course of treatment. In various embodiments, a gain in the somatic chromosomal copy number of chromosome 6p from aqueous humor is highly correlated with severity of retinoblastoma to indicate enucleation as a potential required intervention to cure disease.
Patent WO-2019204446-A1 (WO)
Title: Gabaa positive allosteric modulator compounds, methods of making, and uses thereof
Inventor: TOCZKO MATTHEW
IPC: C07D487/04
Filed: 2019-04-17
Abstract: Described herein are polymorphs comprising 2',6-difluoro-5'-[3-(1-hydroxy-1-methylethyl)-imidazo[1,2-b][1,2,4]triazin-7-yl]biphenyl-2-carbonitrile (TPA023B) or salts thereof. In one aspect, disclosed herein is a crystalline polymorphic salt or co-crystal of TPA023B with phosphoric acid. Also described herein are methods of making and using the same.
Patent WO-2019217560-A1 (WO)
Title: Chemical analysis device and method
Inventor: WRIGHT KENNETH C
IPC: G01N21/71
Filed: 2019-05-08
Abstract: Methods and systems for chemical analysis. For instance, a device for chemical analysis of a sample includes a housing, an inlet, a pump, multiple membranes and at least one detector. The housing contains an interior chamber of the device. The inlet on the housing introduces the sample into the interior chamber. The pump is connected to the housing to form a partial vacuum in the interior chamber. The multiple membranes have different response times to different constituents of the sample. The multiple membranes include at least a first membrane and a second membrane. At least one of the first membrane and the second membrane comprises a tubular portion. The multiple membranes have different response times to different constituents of the sample. The detector is for detecting the different constituents of the sample after interaction with the multiple membranes.
Patent WO-2019217691-A1 (WO)
Title: Kras g12c inhibitors for the treatment of cancer
Inventor: MINATTI ANA ELENA
IPC: A61K31/549
Filed: 2019-05-09
Abstract: Provided herein are KRAS G12C inhibitors of the general formula (I) and pharmaceutical compositions comprising the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.
Patent WO-2019240923-A1 (WO)
Title: Slitting machines and methods for forming rolls of coated films therewith
Inventor: CASARRUBIAS JUAN CARLOS
IPC: B32B37/00
Filed: 2019-05-22
Abstract: A slitting machine (500) includes a laminated film unwinding apparatus (540), a release liner recovery apparatus (550), a cutting apparatus (530), and a plurality of polymer substrate strip rewinding apparatuses (510, 520). The laminated film unwinding apparatus (540) is operable to unwind a roll of laminated film (542) comprising at least a polymer substrate (100) and a release liner (150). The release liner recovery apparatus (550) is operable to wind the release liner (150) that is released from the polymer substrate (100). The cutting apparatus (530) is operable to cut at least the polymer substrate (100) along a machine direction to divide the polymer substrate into strips. The plurality of polymer substrate strip rewinding apparatuses (510, 520) are operable to wind one or more strips of the polymer substrate (100) onto one or more rolls (512, 522). The slitting machine (500) is operable to carry out a method for forming rolls (512, 522) of coated films (100).
Patent WO-2019231851-A1 (WO)
Title: Ethylene-vinyl alcohol resin composition, multilayer structure, multilayer film or sheet, container and packaging material
Inventor: HIROSE WATARU
IPC: B32B27/30
Filed: 2019-05-24
Abstract: Provided is a resin composition containing an ethylene-vinyl alcohol copolymer, a polyamide and a higher fatty acid metal salt, a multilayer structure and a multilayer sheet including the resin composition, and a container and a packaging material including the multilayer sheet. It is particularly concerned with good retort resistance, good thermal stability and good orientability.
Patent WO-2019232169-A1 (WO)
Title: System and method for billpay using credit-based products
Inventor: SPECTOR HOWARD
IPC: G06Q20/00
Filed: 2019-05-30
Abstract: Systems and methods for online billpay using credit products are disclosed. In one embodiment, in an information processing apparatus comprising at least one computer processor, a method for online billpay using a credit product may include: (1) receiving, from a customer, an identification of a merchant for online credit-based bill pay; (2) retrieving accepted payment mechanisms from the merchant; (3) selecting a payment mechanism from the accepted payment mechanisms; (4) receiving an invoice for a customer transaction with the merchant from the merchant; (5) conducting a payment transaction with the selected payment mechanism; and (6) charging the payment transaction to a credit account associated with the customer.
Patent WO-2019240958-A1 (WO)
Inventor: SOYKAL IBRAHIM
IPC: B01J35/00
Filed: 2019-05-30
Abstract: Une composition de catalyseur comprenant MgO, AI2O3 et un ou plusieurs autres oxydes de métal alcalino-terreux, permet une production catalytique de propylène remarquable lorsqu'elle est utilisée conjointement avec un catalyseur de métathèse.
Patent WO-2019246090-A1 (WO)
Title: Presse-étoupe lubrifié à double joint et manchon rotatif
Inventor: MIHM CHRISTOPHER
IPC: F04D29/00
Filed: 2019-06-18
Abstract: L'invention concerne une ou plusieurs techniques et/ou un ou plusieurs systèmes pour atténuer une perte ou une fuite de fluide à partir d'une pompe à fluide (150) avec un arbre rotatif (158) entraînant un mécanisme de pompage. Un composant de presse-étoupe (202) peut avoir un joint interne formé par deux joints toriques dynamiques (322, 324) qui permettent l'utilisation de lubrifiants à des pressions élevées, ainsi qu'un joint externe pour une plus grande prévention de perte de fluide. En outre, le composant de presse-étoupe peut être une reconfiguration pour des composants de presse-étoupe existants de façon à assurer une plus grande durée de vie et une plus grande efficacité par rapport aux composants de presse-étoupe existants. De plus, dans certains modes de réalisation, un manchon (606) peut être fixé de manière fixe à l'arbre rotatif entre le presse-étoupe et l'arbre de façon à constituer un point d'usure pour le presse-étoupe.
Patent WO-2020023157-A1 (WO)
Title: Blob detection using feature match scores
Inventor: FINKELSTEIN NIR
IPC: G06T7/246
Filed: 2019-06-20
Abstract: A computer system is provided that includes a camera device configured to capture images of a physical scene and a processor configured to store a list of identified blobs. Each identified blob includes a determined blob feature and a path of tracked positions for that identified blob. The processor is configured to receive a series of images of the physical scene from the camera device, detect a candidate blob in a candidate image of the series of images, determine a blob feature of the candidate blob and a position of the candidate blob in the candidate image captured by the camera device. For each identified blob in the list, the processor is configured to compute a match score between the candidate blob and that identified blob.
Patent WO-2020014568-A1 (WO)
Title: Systems, methods and computer program products for risk and insurance determination
Inventor: HAILE MUSSIE
IPC: G06Q40/08
Filed: 2019-07-12
Abstract: The invention enables determining at least one of an insurance risk score or an insurance cost through the steps of (i) receiving from one or more sensors disposed within one or more wearable devices worn by the individual, health parameter data corresponding to one or more states associated with the individual, (ii) validating the received health parameter data based on one or more predefined validation rules, (iii) responsive to validation of the health parameter data, recording said health parameter data and a unique ID associated with the individual in a blockchain, and (iv) retrieving from the blockchain, a plurality of instances of health parameter data associated with the unique ID, and generating based on an analysis of the retrieved plurality of instances of health parameter data, a risk score associated with the individual.
Patent WO-2020040911-A1 (WO)
Title: Reporting actual uplink transmission power
Inventor: DING LING
IPC: H04W72/04
Filed: 2019-07-18
Abstract: Method and apparatus are provided for reporting and receiving actual UL transmission power. In accordance with some implementation, a UE may send a first indication of power headroom to a base station. The UE may receive one or more resources allocation for a UL transmission. The UE then may determine actual transmission power to be used in the UL transmission. Upon determination, the UE may transmit the UL transmission and send an indication of the actual transmission power to the base station. The base station, in response to receiving an indication of actual transmission power of the first UL transmission, may adjust an estimate of the link quality based on the receive indication of actual transmission power.
Patent WO-2020028455-A1 (WO)
Title: Blowout preventer testing apparatus and method
Inventor: WEAVER RANDALL
IPC: E21B19/00
Filed: 2019-07-31
Abstract: A blowout preventer including a housing including a central passage and a first aperture, and a first ram assembly slidably disposed in the first aperture, wherein the first ram assembly includes a ram block and an actuator configured to rotate the ram block when the ram block is disposed in the first aperture of the housing.
Patent WO-2020033644-A1 (WO)
Title: Conversational limbic computing system and related methods
Inventor: OGAWA STUART
IPC: G06F17/00
Filed: 2019-08-08
Abstract: A conversational limbic computing system is provided that converses with a patient and provides familiar media content based on the patient's emotions and psychological state. The media content includes audio data of familiar people talking with the patient. It utilizes content learned from the patient and content provided by family, friends, caregivers, and doctors, and autonomously adjusts conversations based on the changing state of the patient's psychological or emotional state.
Patent WO-2020051429-A1 (WO)
Title: Methods and compositions for retinal neuron generation in carrier-free 3d sphere suspension culture
Inventor: QIANG FENG
IPC: C12N5/0797
Filed: 2019-09-06
Abstract: Provided herein, in one aspect, is a population of retinal neurons including photoreceptors precursor cells (PRPCs) generated in vitro from human pluripotent stem cells (hPSCs) that can be used as a cell source for regenerative therapies, drug discovery and disease modeling. Methods and compositions for making and using the same are also provided.