baber/WOPTO huggingface dataset:
Patent WO-03006047-A2 (WO)
Title: Procedes permettant la reduction de l'antigenicite de polypeptides
Inventor: CARR FRANCIS J
IPC: A61K38/02
Filed: 2002-07-12
Abstract: La présente invention à trait au domaine de l'immunologie et de thérapeutique aux protéines. Les protéines thérapeutiques sont des polypeptides à être administrés notamment aux humains. Les polypeptides sont modifiés de sorte que le polypeptide présente une propension réduite à déclencher une réponse immunitaire lors de son administration à un sujet humain. A cet effet, l'invention propose des procédés pour le développement de polypeptides thérapeutiques qui sont moins immunogènes que leurs analogues non modifiés lors de leur utilisation in vivo. Les modification mises en oeuvre selon l'invention ont trait, par exemple, à l'insertion de sites de clivage de la protéase, la fixation de diverses molécules ou l'insertion d'acides aminés synthétiques.
Patent WO-03054544-A2 (WO)
Inventor: MUETHING JOHANNES
IPC: G01N33/573
Filed: 2002-12-20
Abstract: A method for determination of the responsiveness of an individual to mistletoe lectin or to (an) individual mistletoe lectin chain is disclosed, whereby the expression of a membrane-bound receptor for mistletoe lectin is characteristic for a corresponding responsiveness.
Patent WO-03082255-A2 (WO)
Title: Utilisation de mob-5 pour combattre la douleur
Inventor: BARCLAY JANE
IPC: G01N33/50
Filed: 2003-04-02
Abstract: L'invention concerne Mob-5, qui est une cible convenable pour développer un produit thérapeutique destiné à traiter ou à soulager la douleur chronique. L'invention concerne des procédés pour traiter et/ou soulager la douleur chronique et des compositions pharmaceutiques correspondantes comprenant des modulateurs avec un effet inhibiteur ou stimulant sur l'activité de Mob-5 et/ou l'expression génique de Mob-5. L'invention concerne aussi un procédé pour identifier des composés ayant une utilité thérapeutique pour traiter la douleur chronique, y compris pour identifier les composés capables d'inhiber ou de stimuler l'activité et/ou l'expression génique de Mob-5, qui peut également inverser les effets pathologiques de la douleur chronique in vivo.
Patent WO-2004035175-A2 (WO)
Title: Filteranordnung zum abscheiden von partikeln aus einem flüssigen und/oder gasförmigen medium
Inventor: LI ZI
IPC: B01D45/08
Filed: 2003-09-17
Abstract: Zur Lösung der Aufgabe, eine Filteranordnung zur Verfügung zustellen, welche die Gefahr von Unfällen vermindert sowie über höhere Standzeiten verfügt, wird eine Filteranordnung zum Abscheiden von Partikeln aus einem flüssigen und/oder gasförmigen Medium, umfassend ein Gehäuse mit mindestens einem Filterkörper vorgeschlagen, wobei der Filterkörper parallel zur Richtung der Strömung eines die Filteranordnung durchströmenden Mediums im Gehäuse angeordnet ist, und mindestens einem durch den oder die Filterkörper und/oder das Gehäuse gebildeten Kanal, und wobei auf mindestens einer Seite des Filterkörpers mindestens ein in das einströmende Medium hineinragender Vorsprung vorgesehen ist.
Patent WO-2004044021-A2 (WO)
Title: Adhesif de contact chimiquement inerte a adherence amelioree, son procede de production et son utilisation
Inventor: ANDER HANSJOERG
IPC: C08F290/06
Filed: 2003-10-31
Abstract: L'invention concerne des adhésifs de contact chimiquement inertes qui présentent une adhérence améliorée sur des substrats polaires et semi-polaires. L'invention concerne également leur production et leur utilisation, notamment pour la production de rubans adhésifs à adhérence instantanée élevée sur des substrats polaires et semi-polaires.
Patent WO-8904114-A2 (WO)
Inventor: HUESTER BERNHARD
IPC: B60S5/02
Filed: 1989-02-17
Abstract: Um bei einer Kraftfahrzeugtankstelle die für den Tankkunden bestimmte Anzeige seiner Tankdaten sowie den Abrechnungsvorgang und andere Geschäftsabläufe an und mit der Tankstelle zu zentralisieren, ist mindestens einem Betankungs- und Bedienungsgerät (2, 3, 4) auf jeder Längsseite einer Tankinsel ein Bildschirm (10) zugeordnet, dem die beim Tanken entstandenen, durch den Flüssigkeitsmeßmotor ermittelten und in einem zentralen Operatorplatz der Tankstelle umgeformten Meßdaten zuführbar und für den Tankkunden ablesbar sind. Das den Bildschirm (10) aufnehmende Gehäuse (12) weist eine Eingabetastatur (14) sowie Einsteckschlitze (15 und 16) für magnetisch lesbare Identkarten bzw. für Bargeld auf und enthält für einen Dialog mit dem Operatorplatz einen Lautsprecher, eine Ruftaste und ein Mikrofon. Pro Tankplatz ist mindestens eine Video-Kamera vorgesehen.
Patent ES-2070066-A2 (ES)
Title: Method and means of manufacturing number plates, in particular reflecting number plates.
Inventor: RENE HENRY
IPC: B60R13/10
Filed: 1993-01-12
Abstract: The invention relates to a method and device for manufacturing number plates, particularly reflective number plates. The method is characterised in that it involves the following steps: - the manufacture of rough support plates (3) cut to the dimensions of the plates to be produced - treatment of the said plates obtained, so as to form a housing (11) for a second plate or the double slim surface plate (5) on which the characters of the plate to be produced will be formed in conventional fashion - manufacture of the said second slim surface plates (5) cut to the dimensions of the said housing (11) formed on the support plate, and - assembly, using a conventional securing method, of the said second slim surface plate (5) and of the support plate (3), in its housing.
Patent ES-2070067-A2 (ES)
Title: Prodn. of reflective plates, e.g. motor vehicle registration plates
Inventor: RENE HENRY
IPC: B44B5/02
Filed: 1993-01-12
Abstract: A rough support plate (17) is formed by cutting to approximate dimensions, with a recess for receiving a second surface plate (45). The surface plate is cut to dimensions slightly smaller than the support plate, and inserted into the recess of the support plate before application of numbers etc. to its surface. The plates are assembled on a double conveyor line.A first line has a supply (7) of rolled aluminium sheet, which is cut and stamped to form the support plates, and a storage magazine (11) for the half-finished plates. A second line has a supply of aluminium (39) and reflective coating material (37), a cutting head (45) and storage magazine (47). An automatic handling device (49) removes the surface plates from the magazine and places them into the recesses of support plates on the other conveyor.
Patent WO-9325707-A2 (WO)
Inventor: TENORIO MATANZO ANTONIO
IPC: C12Q1/686
Filed: 1993-06-04
Abstract: Les mélanges utilisés pour la réaction de détection s'obtiennent par simple addition d'oligonucléotides, contiennent des séquences homologues sélectionnées parmi les séquences génomiques apparentées et peuvent contenir des séquences non homologues et/ou des modifications par rapport aux séquences connues. Les mélanges utilisés pour la réaction d'identification, consécutive ou non à celle de la détection, s'obtiennent par addition d'oligonucléotides, se terminent à leur extrémité 3' par une séquence spécifique à la séquence à typer, sont configurés de sorte que les fragments spécifiques amplifiés sont différents entre eux par leur taille ou autre marquage physique ou chimique et peuvent contenir des modifications par rapport aux séquences connues. Les nouveaux procédés et mélanges sont particulièrement utilisés pour la détection et le typage d'agents infectieux apparentés, en particulier des virus apparentés.
Patent ES-2068147-A2 (ES)
Title: Dock leveler with an improved automatic material handling vehicle barrier.
Inventor: SPRINGER SCOTT L
IPC: B65G69/28
Filed: 1993-06-04
Abstract: A dock leveler assembly for a loading dock is provided having an adjustable ramp, a pivotally mounted lip and a pivotally mounted barrier plate both disposed at front edge portion of the ramp. The pivotal movement of the lip and the barrier plate are coordinated so that, when the lip is in a depending stored position, the barrier plate may be selectively adjusted to assume either an operative upwardly projecting vehicle barrier mode or an inoperative non-projecting mode allowing material handling equipment to load or unload the rear end of a vehicle parked adjacent the loading dock. When the lip is in an operative cantilevered position bridging a gap formed between the ramp front edge portion and the bed of a parked vehicle the barrier plate assumes the inoperative mode allowing material handling equipment to pass over the ramp and the lip onto the bed of the parked vehicle during loading and unloading thereof.
Patent ES-2079301-A2 (ES)
Title: Improved alcohol meter.
Inventor: MARTINEZ MUNOZ ANTONIO
IPC: G01N33/98
Filed: 1993-10-18
Abstract: For detecting the user's blood alcohol level from his breath with great accuracy, using an ethanol detector 3 and an electronic circuit equipped with a central processing unit. Its main innovations are the inclusion of verbal messages in easily replaceable memories, which are activated in parallel with its visual indicators, and the inclusion of a device 14 for coin operation, in order to facilitate its installation in bars, discotheques, and similar public places. Other innovations are the breathing inlet that can be connected to a straw as used for soft drinks, for greater hygiene in its use, and the incorporation of a remote control for controlling various functions of the alcohol meter.
Patent ES-2092951-A2 (ES)
Title: Process and a device for the rotation-angle-monitored tightening or loosening of screw connections
Inventor: LAMPE MARKUS
IPC: B25B23/14
Filed: 1993-12-17
Abstract: The invention relates to a process and a device for the rotation-angle-monitored tightening or loosening of screw connections by means of power driven tools. The absolute rotation angle swept over in the screwing operation with respect to a fixed point about a swivel axis through the rotation axis of the screw connection is measured. An advantageous, relative-position free, absolute measurement of the rotation angle is effected by the use of an absolute rotation-rate measuring sensor. The rotation-rate sensor can herein be configured as a mechanical, compass-like gyroscope, as a rotation sensor or as an acceleration sensor, by means of which a measured value correlated with the absolute rotation angle can be recorded.
Patent ES-2085236-A2 (ES)
Title: Protection system for telephone terminal strips and the like.
Inventor: GARCIA RAMOS EVARISTO
IPC: H04M1/24
Filed: 1994-03-14
Abstract: Protection system for telephone terminal strips and the like. The system is based on fitting a conductor bridge 3 between the earthing bars 2 situated longitudinally along the sides of a terminal strip 1 used in telephone exchanges, which is equipped with different levels of pairs between the aforementioned earth bars 2. The bridge 3 is formed by two conducting plates 4 and 5 joined at their ends, extending into elastic end plates 6 by means of which the electrical and mechanical connection is made with the earth bars 2, enabling separate protection modules for each pair to be fitted between the plates 4 and 5 of each bridge 3, allowing their individual removal for carrying out any kind of operation, keeping the remaining pairs of this level in operation. Each protection module 9 includes a tripolar gas discharger 12 with its socket outlets 14 and an elastic conducting plate 15 around the electrode, rounded off at the ends 16 that emerge through the sides of the module itself 9 to make contact with the two plates 4 and 5 of the bridge 3 and thus create the corresponding earth connection.
Patent ES-2117547-A2 (ES)
Title: Improved beam with extendible anchoring
Inventor: HERMS GALVADA ANTONIO
IPC: E04G23/02
Filed: 1995-11-06
Abstract: The recommended beam with extendible anchoring consists basically of a conventional "IPE" beam, in which fastening elements have been arranged and, at its ends, the corresponding means for securing the ends of the beam of variable length to the load-bearing walls. The securing means which are incorporated at the ends of the conventional beam are formed by a support formed by a planar part and an angular part, arranged at the ends of the planar part, the support being secured to the walls by means of the corresponding screws or rods or, alternately, directly embedded in the vertical planes of the load-bearing walls, inside walls or partitions.
Patent WO-0220385-A2 (WO)
Title: Installation and method for conditioning a sheet of moulding material
Inventor: GAY JEAN-LOUIS
IPC: B65H19/30
Filed: 2001-09-05
Abstract: The invention concerns an installation comprising: at least two locations (15, 15') for positioning coils (14, 14') winding a sheet (2) of moulding compound material, said locations being in succession along a globally horizontal direction (X-X'); a carriage (20) consisting of a main frame (20A) and a secondary frame (20B), provided with rollers (22) guiding the sheet (2) and mobile (F4) in translation, along said direction (X-X'), between a first position located globally above the first location (15) and a second position located globally above the second location (15'), and reciprocally, the main (20A) and the secondary (20B) frames being capable of sliding relative to each other parallel to said horizontal direction (X-X').
Patent WO-03104517-A2 (WO)
Title: Method and device for incorporating a compound in the pores of a porous material and uses thereof
Inventor: TRAN-THI THU-HOA
IPC: B01J20/286
Filed: 2003-06-06
Abstract: The invention concerns a method and device for incorporating a compound in the pores of a porous material selected among microporous and mesoporous materials obtained by sol-gel process, as well as the uses of said method and said device. The method comprises vaporization or sublimation of the compound in a chamber containing the porous material. The invention is useful for doping microporous or mesoporous materials obtained by sol-gel process and, in particular, materials mesoporous relative to structuring surfactants, for making chemical sensors and multisensors, molecular sieves, selective filtering membranes, stationary phases for chromatography, optical or optoelectronic materials.
Patent FR-2283603-A2 (FR)
Title: Branched control for repeaters in transmission channel - has switch pair to open parallel path across selectors during node selection
Inventor: MERLET PIERRE
IPC: H04B17/40
Filed: 1974-08-28
Abstract: The installation is for control of a repeater in a transmission channel, the repeater having half repeaters in a loop. At each mode, a first switch and a second switch are arranged in a connection which is in parallel with channel service selection devices which equip the pair of points at the mode. The selection devices are respectively controlled by the circuit of the selection system at this mode. The point control device of the service section before this mode operates on one of the service sections behind this mode. The connection is opened at the moment of selection of one repeater and closed at the moment of selection of a repeater belonging to a system other than that at the mode considered.
Patent FR-2458280-A2 (FR)
Title: Compsn. for removing make-up from the eyes - contg. ethoxylated glycerol fatty acid ester, specified preservative and water
Inventor: KOULBANIS CONSTANTIN
IPC: A61K8/86
Filed: 1979-06-08
Abstract: The compsn. contains in aq. soln. (1) at least one surfactant selected from polyethoxylated esters of 12-18C fatty acids and glycerol, the esters having an HLB of 15-18; at least one preservative selected from sodium ethylmercuri-thiosalicylate, a chlorhexidine salt, a phenylmercury salt, a mixture of 30% sodium benzoate and 70% monochloroacetamide, and a dimethyl benzyl alkyl ammonium chloride in which alkyl is 12-18C or mixed alkyl radicals pref. 12-14C and 14-16C radicals and (3) a phosphate buffer, the compsn. having a pH of 6.5-7.5. The compsns. do not sting or irritate and have excellent storage stability using another class of surfactant to that of the principal patent.
Patent FR-2498378-A2 (FR)
Title: Short circuiting piston for HF coaxial line - has spring lamellas varying diameter to make contact with conductors
Inventor: ROZENFELD LUCIEN
IPC: H01P1/28
Filed: 1981-01-20
Abstract: The short circuit piston includes two flat annular plates situated parallel to each other. They are joined together internally and externally by two flexible metal bands which form two curved rings projecting inwards and outwards. By varying the distance between the two plates, the radius of curvature of the two metal bands may be changed. Outside the outer band there is a set of tongues, each of which ends in a piece of composite metal material which is self lubricating. The tongues press against the inner surface of the outer conductor. The pressure may be varied by altering the distance between the two annular plates.
Patent FR-2502302-A2 (FR)
Title: Procede d'allumage d'une flamme de bruleur circulaire fonctionnant au poussier de charbon
Inventor: LEIKERT KLAUS
IPC: F23D1/00
Filed: 1982-03-05
Abstract: L'INVENTION CONCERNE UN PROCEDE D'ALLUMAGE D'UNE FLAMME D'UN BRULEUR CIRCULAIRE A POUSSIER DE CHARBON AVEC UNE ZONE DE COURANT INVERSE INTERNE, SUIVANT LEQUEL L'ENERGIE D'ALLUMAGE EST INTRODUITE AU CENTRE DANS LA ZONE DE COURANT INVERSE INTERNE DE LA FLAMME DU BRULEUR CIRCULAIRE A POUSSIER DE CHARBON. LE PROCEDE EST CARACTERISE EN CE QUE LA PROPORTION PONDERALE ENTRE L'AIR VEHICULAIRE DE POUSSIER DE CHARBON ET LE POUSSIER EST COMPRISE ENTRE 0,5 POUR LA FLAMME D'ALLUMAGE DE POUSSIER, LA PROPORTION PONDERALE D'AIR VEHICULAIRE DE POUSSIER ET DE POUSSIER ETANT COMPRISE ENTRE 1,5 ET 2,0 POUR LA FLAMME DE BRULEUR PRINCIPAL.
Patent FR-2524642-A2 (FR)
Inventor: ARCHER MICHEL
IPC: G01N3/06
Filed: 1982-03-30
Abstract: The present invention relates to an improved fatigue damage indicator for a mechanical member subjected to repetitive stress, comprising two thick elements which are spaced from one another and are connected one to the other by a thin web or plate formed with a slot and at least one pair of free opposite edges, the two elements being so connected with the mechanical member or fixed to the latter so that they are displaceable relative to one another in a plane parallel to the plane of the thin plate, the thick elements being disposed so as to be separated from one another in a direction substantially perpendicular to their direction of relative displacement by such stress, the thin plate being placed under shear force in its plane by such relative displacement, the slot of the thin plate extending from one of the edges of the web in the said direction and terminating short of the opposite edge in a blind end of the slot having two corners so that, with application of stress, two cracks develop at corners of the bottom of the crack and are propagated progressively in the web towards an opposite edge of the thin plate so that said cracks meet cracks propagating generally in a direction away from said opposite edge to detach, or substantially detach, a central zone of the thin plate delimited by said cracks, wherein the thick elements of the fatigue damage indicator are connected to each other not only by thin webs but in addition by two narrow, elongated struts disposed on either side of the web and directed perpendicularly to the axis of one or the two slots in this web.
Patent FR-2542103-A2 (FR)
Title: Optical reflection system which can be fitted to a photographic apparatus, camera or television making it possible to obtain the reduction and the reproduction of a space with a perception of three-dimensionality (relief)
IPC: G02B27/22
Filed: 1983-03-04
Abstract: The optical system is an interchangeable objective, or the main constituent of an apparatus, the device of which may comprise a spherical casing 1, a shutter 2, a plane film housing 3, a telescopic conduit 4, a locking tube 5, and a retention ring 6. A plano-convex lens, together with its lens shield 7, is provided on an axial surface and, inside, a crystal sphere 8 is followed by a plano-concave lens 9 and an additional magnifying glass 10 and a viewing window 11. The assembly is completed by a threaded rod with knurled wheels 12 for fixing and adjusting; it is supported by a crosspiece 13 with, underneath, a clamping screw 14 and a locking device 15. The optical system according to the invention is particularly intended for obtaining a photographic image with a wide-angle view, free of distortions and giving an impression of three-dimensionality (relief), and for extending its application into the visual and audiovisual fields.
Patent FR-2615514-A2 (FR)
Title: Cloning of the bioC and bioH genes of Bacillus sphaericus, vectors and transformant cells and process for preparing biotin
Inventor: GLOECKLER REMI
IPC: C12P17/18
Filed: 1987-05-18
Abstract: The present addition relates to a DNA sequence according to one of Claims 1 and 4 to 6 of the parent patent, characterised in that it encodes the enzymes which are products of the genes:     . bioF and bioC   . bioF and bioH   . bioF, bioC and bioH.
Patent FR-2630113-A2 (FR)
Title: 2-[(4-Piperidyl)methyl]-1,2,3,4-tetrahydroisoquinoline derivatives, their preparation and their application in therapeutics
Inventor: GEORGE PASCAL
IPC: C07D401/14
Filed: 1988-04-19
Abstract: Compounds corresponding to the general formula in which R represents either a linear or branched C2-C6 alkyl group, or a linear or branched C3-C6 cycloalkyl group, or an allyl group, or a cinnamyl group, or a 3-phenylpropyl group, or a phenylcarbonylmethyl group, or a benzyl group substituted by one to three fluorine atoms, two to three chlorine atoms, one to three trifluoromethyl groups, a cyano group, an aminocarbonyl group, a nitro group, an amino group, a dimethylamino group, a methylthio group, two to three methyl groups, a C2-C4 alkyl group, two to three methoxy groups or an ethoxy group. Application in therapeutics.
Patent WO-0077241-A2 (WO)
Title: Recherche d'heparanase
Inventor: BRENCHLEY PAUL ERNEST CHARLES
IPC: C12M1/40
Filed: 2000-06-12
Abstract: La présente invention concerne la recherche d'activité héparanase dans un échantillon. Ce procédé se déroule en plusieurs temps. (i) On met à incuber de l'échantillon en présence d'un premier support en phase solide sur lequel est immobilisé un substrat polymère HSGAG convenant à l'héparanase. Ce substrat, qui est insensible à l'action des protéases, comporte une liaison avec un premier fragment de liaison et un régulateur cellulaire de la paracrine capable de se lier au HSGAG. (ii) On traite l'échantillon incubé avec un second support en phase solide pourvu d'un second fragment capable d'immobiliser le substrat polymère du HSGAG clivé provenant du premier support solide sur ledit second support en phase solide, et ce par liaison dudit second segment de liaison, soit avec le régulateur cellulaire de la paracrine, soit avec le premier fragment de liaison. (iii) On génère un signal mesurable de l'autre, le premier ou du second segment, suivant le cas, du substrat clivé immobilisé dans la phase solide du second support. (iv) Enfin, on mesure le signal produit sur le second support en phase solide séparé du premier support en phase solide.