baber/WOPTO huggingface dataset:
Patent IL-99761-A0 (IL)
Title: Purified immunoglobulins,their preparation and pharmaceutical compositions containing them
IPC: C07K14/00
Filed: 1991-10-16
Abstract: Following are described. (A) purified prepn. of an anti-CDw52 antibody which exhibits on size exclusion chromatography a single peak under non-reducing conditions and 2 major peaks under reducing conditions; esp. the prepn. exhibits on conventional SDS polyacrylamide gel electrophoresis, one main band using a non-reduced sample and two main bands using a reduced sample; (B) purified prepn. of an anti-CDw52 antibody having a specific activity greater than 0.8 KU/mg; (C) purified prepn. of an anti-CDw52 antibody, free from host cell contaminants and/or aggregates; (D) purifying an anti-CDw52 antibody comprising (a) applying an aqs. soln. of the antibody to a Protein A column so as to absorb the antibody and eluting the antibody with an acid soln., (b) applying the acidic eluate to an ion-exchange column of charged particles to absorb the antibody and then eluting the antibody with an aqs. soln. of counter-charged ions and (c) applying the aqs. eluate to a size exclusion column of porous particles to retain non-antibody mols. in the porous particles and to obtain the desired antibody in selected fractions produced from the column. Pref. the Protein A column is Protein A Sepharose and the antibody is eluted with citric acid.
Patent AU-PO755097-A0 (AU)
Title: Receptor agonist and antagonist
IPC: A61K38/08
Filed: 1997-06-25
Abstract: The present invention relates to novel cyclic or constrained acyclic compounds which modulate the activity of G protein-coupled receptors and are useful in the treatment of conditions mediated by G protein-coupled receptors, for example, inflammatory conditions.
Patent FI-20030438-A0 (FI)
Inventor: RUOTANEN KYOESTI
IPC: C04B20/00
Filed: 2003-03-25
Abstract: The invention relates to a method for manufacturing a heat-resistant and heat-insulating structure. According to the invention, a dry matter composition is formed containing 10-60 w-% fine fraction the particle size of which is < 0.1 mm and which includes a dry component that binds air bubbles, and 40-90 w-% coarse fraction the particle size of which is > 0.1 mm, and 5-20 w-% water is mixed into the dry matter composition to form a substantially homogenous and flowing structural material, and the structural material is moulded into the desired structural shape, and water is evaporated from the structural material to form a heat-resistant and heat-insulating structure. Furthermore, the invention relates to a heat-resistant and heat-insulating structure, as well as to a structural material and dry matter composition for use in the manufacture of a heat-resistant and heat-insulating structure.
Patent IL-102059-A0 (IL)
Title: Production of a whey protein hydrolyzate
IPC: A23J3/30
Filed: 1992-05-29
Abstract: PCT No. PCT/DK92/00170 Sec. 371 Date Nov. 30, 1993 Sec. 102(e) Date Nov. 30, 1993 PCT Filed May 27, 1992 PCT Pub. No. WO92/21248 PCT Pub. Date Dec. 10, 1992A well tasting and organoleptically acceptable whey protein hydrolyzate is produced in high yield by a method using a combination of non-pH-stat hydrolysis and ultrafiltration. Preferably, the method is carried out by mixing a material containing at least 65% whey protein as dry matter and water to form a slurry containing a whey protein content of about 7-20%, heating the slurry to above 600 DEG  C., adjusting the pH of the slurry to about 8, hydrolyzing the slurry with at least two different proteases to a degree of hydrolysis of between 17 and 35% without adjusting the pH during hydrolysis to produce a hydrolyzed slurry, inactivating the proteases and separating the hydrolyzed slurry with an ultrafiltration unit having a cut-off value above 10,000 to form a permeate containing the whey protein hydrolyzate. One protease may be obtained from B. Licheniformis and the other from B. Subtilis. The hydrolyzed slurry or the permeate may be treated with activated carbon, and the permeate may be concentrated by nanofiltration and/or by evaporation.
Patent IL-115139-A0 (IL)
Title: Grooved phaco-emulsification needle
IPC: A61M1/00
Filed: 1995-09-01
Abstract: A phase-emulsification needle (20) is provided for use with a plastic or elastomeric sleeve (17), the needle having a mid-region portion defining a plurality of outwardly extending projections (24) forming longitudinally-oriented grooves (30) that provide adequate irrigant flow rates to the anterior chamber of the eye, even when the entry wound compresses the sleeve (17) against the outer surface of the needle (20), thereby reducing the risk of collapse of the anterior chamber due to inadequate irrigant flow and reducing the risk of excessive heat transmission to the entry wound. <IMAGE>
Patent IL-125990-A0 (IL)
Title: Electrocoagulation apparatus
IPC: A61N1/06
Filed: 1998-08-30
Abstract: Electrocoagulation apparatus (10) including an array of more than two RF energized needles (12), and an RF generator (28) for selectively energizing at least two of the needles (12) so that energy passes therebetween. The needles (12) may be arranged in rows, and the rows may be staggered. Alternatively, the needles (12) may be arranged in a matrix of rows and columns. The needles (12) may be generally equally spaced from each other or randomly arranged. Preferably the needles (12) are spaced from each other corresponding to a width of a vein. The apparatus is used for non invasive electro coagulation of varicose veins. <IMAGE>
Patent IL-140053-A0 (IL)
Title: Method for encapsulating solder metal powders and solder metal powders produced according to this method
Inventor: SCHULZE JURGEN
IPC: B23K35/363
Filed: 1999-06-15
Abstract: A method is disclosed for encapsulating solder metal powders and the microencapsulated metal solder in such a way that the metal powder is reliably protected from external oxidizing influences and the capsule only releases the metal powder as a result of the influence of temperature, without the influence of soldering flux.
Patent IL-141152-A0 (IL)
Title: In-vitro method for detecting and diagnosing acute coronary syndromes
Inventor: DANNE OLIVER
IPC: G01N33/82
Filed: 1999-08-11
Abstract: The invention relates to an in vitro method of recognizing acute coronary syndroms, especially an acute myocardial infarction, by determining and evaluating the content of choline, choline and/or trimethyl ammonium derivatives selected from the group comprising phosphoryl choline, plasmalogens, and lysoplasmenyl choline, and/or the reaction products thereof selected from the group comprising 1-O-alk-1'-enyl-2 substituted glycerol and 1-O-alk-1'-enyl-2 substituted glycerol phosphate in body fluids or component parts of the body, said method comprising the following steps:drawing a sample of a suitable body fluid or component part of the body; determining the content of choline, choline and/or trimethyl ammonium derivatives selected from the group comprising phosphoryl choline, plasmalogens, and lysoplasmenyl choline, and/or the reaction products thereof selected from the group comprising 1-O-alk-1'-enyl-2 substituted glycerol and 1-O-alk-1'-enyl-2 substituted glycerol phosphate by a suitable method of determination (nuclear magnetic resonance methods, biochemical, enzymatic, immunological, clinical-chemical, chromatographic, mass spectrometric, electrochemical, photometric methods, or other methods); and evaluating the measured results, taking into account a limit value for recognition or exclusion of acute coronary syndroms, especially an acute myocardial infarction.
Patent IL-141252-A0 (IL)
Title: Method and device for non-destructive control of a surface using a dye product
IPC: G01N21/91
Filed: 1999-08-05
Abstract: A method is presented for non-destructive testing of the state of a surface that may have cracks in it by observing waves emitted by a dye applied to the surface and present in the cracks in response to an incident excitation beam of wavelength appropriate to the dye. The incident excitation beam is an ultraviolet light. The beam is made of rectilinear polarized waves. Waves emitted by the dye are observed through a rotatable polarized wave analyzer. The analyzer is rotated first to eliminate from observation the wave due to the residual dye on the surface and thereafter to determine the depths of the cracks.
Patent IL-146468-A0 (IL)
Title: Amide substituted imidazoquinolines
IPC: A61P33/02
Filed: 2000-06-08
Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain amide functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
Patent IL-148069-A0 (IL)
Title: Method and apparatus for detecting zero rate frames in a communications system
IPC: H04B7/005
Filed: 2000-08-31
Abstract: Techniques for detecting zero rate frames in a received data transmission. A modulated signal is received and demodulated in accordance with a particular demodulation format to generate demodulated symbols. The demodulated symbols are partitioned into a number of received frames. For each received frame, a quality metric is computed and compared against a threshold value. The threshold value is selected based, in part, on the quality metrics of received frames. Based on the comparison result, the received frame is indicated as being either transmitted and received in error (i.e., erased or bad) or not transmitted at all (i.e., zero rate or empty). The quality metric can relate to an energy of a received frame, a distance between a received frame and a codeword corresponding to the received frame, or other metrics. The threshold value can be selected based on the quality metrics computed for decoded frames or received frames identified as good, and can be dynamically adjusted based on current information available at the receiver. The method is advantageously used in a CDMA communications system.
Patent IL-150210-A0 (IL)
Title: Novel compounds
IPC: A61P37/02
Filed: 2000-12-15
Abstract: The present application is directed to compounds having the structure of Formula I:where R<1 >is phenyl, pyridinyl, thiophenyl, furanyl, imidazolyl or trazolyl, each optionally substituted by a straight or branched C1-C6 alkyl, NO2, CF3, C1-C6 alkoxy, chloro, fluoro, bromo, or iodo;where R<a >and R<b >are independently selected from hydrogen, a straight or branched C1-C6 alkyl, NO2, C1-C6 alkoxy, chloro, fluoro, bromo, or iodo; and where X is O or CH3.The compounds may be incorporated into pharmaceutical compositions and administered to patients as a treatment for pain, gastrointestinal disorders, spinal injury, or disorders of the sympathetic nervous system.
Patent IL-151752-A0 (IL)
Title: Diamond radiation detector
IPC: G01T1/24
Filed: 2001-03-13
Abstract: A radiation detector comprises a boron-doped diamond substrate ( 10 ) having an overlayer ( 12 ) of diamond epitaxially grown on surface ( 14 ) of the substrate ( 10 ). The top surface ( 16 ) of the layer ( 12 ) is provided with an interdigitated electrode array ( 18 ) in electrical contact therewith.
Patent IL-171940-A0 (IL)
Title: A smoking composition
Filed: 2005-11-14
Abstract: The invention provides a smoking composition for a Hookah. Various flavours both natural and synthetic may be added to improve the quality of smoke and impart good smell. A method of making the smoking composition is also disclosed.
Patent IL-174251-A0 (IL)
Title: Use of suifonamide derivatives for the preparation of medicaments
IPC: A61K31/18
Filed: 2006-03-12
Abstract: The present invention is related to the use of sulfonamide derivatives in the treatment of metabolic disorders mediated by insulin resistance or hyperglycemia, comprising diabetes type II, inadequate glucose tolerance, insulin resistance, obesity, polycystic ovary syndrome (PCOS). Formula (I). R1 is selected from the group comprising or consisting of hydrogen, C1-C6-alkoxy, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, amino, sulfanyl, sulfinyl, sulfonyl, sulfonyloxy, sulfonamide, acylamino, aminocarbonyl, C1-C6 alkoxycarbonyl, aryl, heteroaryl, carboxy, cyano, halogen, hydroxy, nitro, hydrazides. R2 is selected from the group comprising or consisting of hydrogen, COOR3, —CONR3R3′, OH, a C1-C4 alkyl substituted with an OH or amino group, a hydrazido carbonyl group, a sulfate, a sulfonate, an amine or an ammonium salt. Y is an 4-12-membered saturated cyclic or bicyclic alkyl containing at least one nitrogen atom, whereby one nitrogen atom within said ring is forming a bond with the sulfonyl group of formula I thus providing the sulfonamide.
Patent IL-177163-A0 (IL)
Title: Audio coding
IPC: G10L19/00
Filed: 2006-07-31
Abstract: Coding an audio signal of a sequence of audio values into a coded signal includes determining first and second listening thresholds for first and second blocks of audio values of the sequence of audio values; calculating versions of first second parameterizations of the parameterizable filter such that the transfer function thereof roughly corresponds to the inverse of the magnitude of the first and second listening thresholds, respectively; filtering a predetermined block of audio values of the sequence of audio values with the parameterizable filter using a predetermined parameterization which depends on the version of the second parameterization to obtain a block of filtered audio values corresponding to the predetermined block which is quantized; forming a difference between the versions of the first and second parameterizations; integrating information on, inter alias, the difference into the coded signal.
Patent IL-181031-A0 (IL)
Title: Integrated permeate channel membrane
Filed: 2007-01-29
Abstract: The present invention is related to a membrane, comprising a permeate channel consisting of a 3D spacer fabric having an upper and a lower fabric surface (2,3) spaced apart by monofilament thread (4) at a predefined distance, said permeate channel being interposed between two membrane layers (12,13), wherein said membrane layers are linked at a multitude of points with said upper and lower fabric surfaces to form an integral structure with a high bonding strength suitable for backflush operation.  The present invention further relates to a method for providing an integrated permeate channel membrane comprising the steps of:  Providing a 3D spacer fabric comprising an upper and lower surface fabric (2,3) spaced apart by monofilament thread (4) at a predefined distance, and  Applying a membrane layer to both said upper and said lower surface fabric.
Patent IL-185957-A0 (IL)
Title: Low power array multiplier
Filed: 2007-09-16
Abstract: An array multiplier comprises a partial product array including a plurality of array elements and a final carry propagate adder. Operands smaller than a corresponding dimension of the partial product array are shifted toward the most significant row or column of the array to reduce the number of array elements used to compute the product of the operands. Switching activity in the unused array elements may be reduced by turning off power to the array elements or by padding the shifted operands with zeros in the least significant bits. Additional power saving may be achieved by having bypass lines in the partial product array that bypasses non-essential array elements and by feeding partial sum and carry directly to the final carry propagate adder. Elements of the carry propagate adder may also be bypassed to achieve further power reduction.
Patent RO-129417-A0 (RO)
Title: Synergistic antimicrobial composition with fungicidal and insecticidal effect, for treating wood
Inventor: IONAŞ CORINA AMELIA
IPC: A01N33/12
Filed: 2013-11-07
Abstract: The invention relates to an antimicrobial composition with fungicidal and insecticidal effect for the treatment of wood. According to the invention, the composition consists of 0.01...35% 4,5-dichloro-2H-isothiazol-3-one, 0.01...20% synthetic insecticide, 0.01...45% quaternary ammonium compound, 10...25% non-ionic emulsifier with an HLB value of at least 7, 15...35% an organic polar solvent and, for the remainder, an aromatic solvent such as xylene, ethylbenzene, toluene or a mixture thereof, the percentage being expressed by mass.
Patent RO-131327-A0 (RO)
Title: Process for purifying wastewater by separating sulphate ion as ettringite with aluminium hydroxylated products recovered from water
Inventor: DINU LAURENŢIU RĂZVAN
IPC: C02F101/20
Filed: 2016-04-06
Abstract: The invention relates to a process for purifying usual acidic wastewater such as pit water and industrial wastewater. The process, as claimed by the invention, consists in the recovery of aluminium from wastewater, in one step of semi-selective precipitation, at a pH of 4.5...5.5, as amorphous hydroxylated products, mostly Al(OH), reacting in the reaction of ettringite formation, and the utilization of the products obtained thereby for precipitating sulphate ions as ettringite, either only after some intermediary treatment steps which allow the concentration of sulphate ions in the water to be reduced by precipitation as CaSOx2HO up to 1450...1750 mg/l, or directly in the ettringite precipitation reaction stage for purifying wastewater polluted with sulphate ions.
Patent RO-133548-A0 (RO)
Title: Process for preparing a gel based on natural extracts, to be used in haemorrhoidal disease therapy
Inventor: IVOPOL MARIA
IPC: A61K36/77
Filed: 2018-12-03
Abstract: The invention relates to a process for preparing a gel based on natural plant extracts, meant to be used in haemorrhoidal disease therapy. According to the invention, the process consists in extracting active principles from the species Allium ampeloprasum (wild leek), Vitis vinifera (grape vine) and Aesculus hippocastanum (horse chestnut) and preparing the plant extracts as aqueous solutions having a content of polyphenol expressed as gallic acid of 386.4...655.8 mg/l and a total flavonoside content expressed as quercetol of 9.08...11.72 mg/l, to be combined in a ratio of 1:1:1 and incorporated in a carbogel base 2%, in a plant extract : carbogel mass ratio of 6:4, resulting in a gel which exhibits a content of active principles of 54.40...92.33 mg/100 g of total polyphenols expressed as gallic acid and 0.89...1.05 mg/100 g of total flavonoside expressed as quercetol, good spreading capacity and a pH value of 8.4...8.8.
Patent RO-135640-A0 (RO)
Title: Use of immunoglobulins y for skin and mucosal diseases
Inventor: NICOLESCU ANCA MARIA
IPC: C07K16/02
Filed: 2021-12-09
Abstract: The invention relates to a biologically active product composition with antibacterial, antifungal and virucidal action based on specific antibodies in combination with healing, re-epithelializing and restructuring substances to be used in skin and mucosal diseases. According to the invention, the composition consists in mass percentages of 10 ... 70% polyclonal or monoclonal antibodies IgY, 3 ... 5% honey, 2..3% nicotinamide, 0.5 ... 1% Arnica Montana, Calendula Officinalis and Aloe extracts, respectively, and for the remainder pharmaceutically acceptable ingredients for the formulation as a solution, gel, cream or ovules.
Patent IE-910660-A1 (IE)
Title: A method for influencing beta-lactam antibiotic production¹and for isolation of large quantities of acv synthetase
IPC: C12N1/15
Filed: 1991-02-27
Abstract: Novel methods and compositions are provided for the enhanced production of fermentable or known and new  beta -lactam antibiotics. The process is exemplified by the production of penicillin. In addition, the P.chrysogenum and A.chrysogenum  delta -(L- alpha -aminoadipyl)-L-cysteinyl-D-valine synthetase genes have been isolated and sequenced. Also methods are provided for the production of  delta -(L- alpha -aminoadipyl)-L-cysteinyl-D-valine synthetase using recombined DNA techniques.
Patent MA-22495-A1 (MA)
Inventor: DICKNETTE G
IPC: A61K31/555
Filed: 1992-04-07
Abstract: Derivatives of amidinophenylalanine, procedure for their preparation, their utilisation and pharmaceutical compositions which contain these compounds are described.
Patent MA-27644-A1 (MA)
Title: Sechage
Inventor: MAYERESSE YVES
IPC: A61P31/12
Filed: 2005-05-11
Abstract: Cette invention a trait à un procédé de séchage de prélèvements biologiques et autres prélèvements instables, permettant de les conserver sous forme de liquides à haute viscosité. Le procédé consiste à préparer un prélèvement à protéger par dissolution et/ou mise en suspension d'un agent actif dans une solution contenant un agent de stabilisation, à soumettre ce prélèvement aux effets d'une température et d'une pression telles que le solvant s'évapore et ce, sans congélation ni formation de bulles, afin d'obtenir une mousse et à extraire le solvant jusqu'à ce que le prélèvement sèche en formant un liquide à haute viscosité.
Patent MA-40672-A1 (MA)
Title: Composes hétérocycliques substitues par amide, utiles comme modulateurs d'il-12, il-23 et/ou de réponses a l'ifna
Inventor: MOSLIN RYAN M
IPC: C07D403/12
Filed: 2013-11-07
Abstract: La présente invention concerne des composés ayant la formule (1) suivante:ou un stéréoisomère ou un sel pharmaceutiquement acceptable de ceux-ci, où r1 , r2 , r3 , r4 et rs sont tels que définis dans la description, qui sont utiles dans la modulation de il12, il-23 et/ou fna, en agissant sur la tyk-2 pour provoquer. L'inhibition de la transduction de signal.
Patent UY-24809-A1 (UY)
Title: Disposicion de doble transmisor con conmutacion auxiliar
Inventor: BOSSARD BERNARD
Filed: 1997-12-12
Abstract: Una disposición de transmisión para funcionamiento de múltiples canales, que comprende al menos dos transmisores, cada uno de los cuales tiene una entrada respectiva y una salida respectiva, medios para conectar las salidas respectivas con al menos un elemento de comunicación (par de antenas omnidireccional), medios para proporcionar o suministrar primeras señales de entrada, que corresponden a al menos un primer canal, a la entrada del primero de los transmisores mencionados, medios para proporcionar o suministrar segundas señales de entrada, que corresponden al menos un segundo canal, a la entrada del segundo de los transmisores, medios para percibir una perdida de señal de salida desde uno de los transmisores, y medios, que responden a la percepción de una perdida de las señales de salida desde uno de los transmisores, para proporcionar ambas señales de entrada a la entrada del otro de los transmisores mencionados, con lo que dicho otro de los transmisores transmite entonces dichos canales primero y segundo. Cada transmisor incluye una unidad conversora de frecuencia y una unidad de salida de RF.
Patent UY-28447-A1 (UY)
Title: Compuestos químicos
Inventor: TUDKER HOWARD
IPC: A61K31/445
Filed: 2004-07-30
Abstract: Un compuesto de fórmula (I): en donde R1, R2, R3, A y n son como se definen; y X es S (O) 2NR4R5 o NR6S(O)2R7; composiciones que los contienen, procedimientos para su preparación y su uso en terapia médica (por ejemplo modulando la actividad del receptor CCR5 en un animal de sangre caliente).
Patent UY-31394-A1 (UY)
Title: Anticuerpos que se unen a il-4y/o il-13 y sus usos
Inventor: MATTHEW DAVISON
IPC: A61K38/19
Filed: 2008-10-15
Abstract: La presente invencion se refiere a nuevos anticuerpos anti-IL-4 y IL-13 humanizados y a fregmentos de los mismos, y a nuevos anticuerpos biespecíficos y fragmentos de los mismos que se unen específicamente a IL-4 y a IL-13. La invencion también incluye usos de los anticuerpos para tratar o prevenir enfermedades o trastornos mediados por IL-4 y/o il-13, incluyendo asma alérgica y dermatitis.