baber/WOPTO huggingface dataset:
Patent RU-2515063-C9 (RU)
Title: Мутеины липокалина слезной жидкости, обладающие аффинностью к с-мет рецепторной тирозинкиназе человека, и способы их получения
Inventor: MATSHINER GABRIEHLE
IPC: A61K38/16
Filed: 2009-01-29
Granted: 2014-08-10
Abstract: Изобретение относится к области биотехнологии, конкретно к мутеинам липокалина слезной жидкости человека, и может быть использовано в медицине. Мутеин липокалина слезной жидкости человека (hTLc) имеет обнаруживаемую аффинность связывания с рецепторной тирозинкиназой Met (c-Met) человека, или ее доменом, или фрагментом c-Met человека. Мутеин содержит от 6 до 18 аминокислотных замен относительно аминокислотной последовательности зрелого липокалина слезной жидкости человека (SWISSPROT DATABANK ENTRY P31025; SEQ ID NO:36), которые выбраны из группы, состоящей из Arg 26→Thr, Val, Pro, Ser, Gly; Glu 27→Gln, Gly, Val, Ser; Phe 28→Met, Asp; Pro 29→Leu, Ile, Ala, Trp; Glu 30→Leu, Gly, Arg, Phe; Met 31→Ser; Asn 32→Leu, Arg, Val, Gln; Leu 33→Tyr, Val, Ile, Thr, Phe; Glu 34→Val, Arg, Ala; Leu 56→Asn; Ile 57→Gln; Ser 58→Ile, Val; Asp 80→Tyr; Lys 83→Ala; Glu 104→Asp; Leu 105→Thr; His 106→Trp и Lys 108→Gly. Также мутеин может дополнительно содержать следующие замены: Cys 61→Ser; Cys 101→Ser; Cys 153→Ser; Arg 111→Pro; Lys 114→Trp; Thr 37→Ser; Met 39→Ile, Leu; Asn 48→Ser; Lys 52→Thr, Met; Met 55→Leu; Lys 65→Arg, Leu; Ala 79→Leu, Ser; Ala 86→Thr; Ile 89→Ser, Gln, Thr, His; Thr 40→Cys; Glu 73→Cys; Arg 90→Cys; Asp 95→Cys; Lys 121→Cys; Asn 123→Cys и Glu 131→Cys. Изобретение позволяет эффективно лечить патологические расстройства, в которые вовлечен путь HGF/c-Met, а также проводить идентификацию c-Met человека в образце. 12 н. и 38 з.п. ф-лы, 16 ил., 9 табл., 25 пр.
Patent RU-2544820-C9 (RU)
Title: Колесо обозрения
Inventor: GNEZDILOV VLADIMIR ALEKSEEVICH
IPC: A63G1/00
Filed: 2013-05-22
Granted: 2015-11-10
Abstract: Изобретение относится к индустрии развлечений. Колесо обозрения может быть сопряжено с водоемом искусственного или естественного происхождения, для чего оно содержит вращающуюся конструкцию с пассажирскими модулями, установленную на двух парах опор, расположенных V-образно, каждая из которых концами ветвей соединена с соответствующими концами оси вращающейся конструкции. Для придания устойчивости колесу обозрения используется расположенный над поверхностью водоема упор, соединенный с опорами в зоне их соединения с осью. Технический результат - упрощение опорной системы колеса обозрения. 7 з.п. ф-лы, 5 ил.
Patent RU-2670634-C9 (RU)
Title: Engine of internal combustion with variable degrees of compression and method of training therefor
Inventor: OKAMOTO KAZUHIKO
IPC: F02B75/32
Filed: 2015-06-25
Granted: 2018-12-04
Abstract: FIELD: motors and pumps.SUBSTANCE: variable compression ratio internal combustion engine is equipped with variable compression ratio mechanism (10) capable of varying the compression ratio of the engine in accordance with the angular position of control shaft (14) and housing (22), which accommodates drive motor (20) for changing and retaining the angular position of control shaft (14). Learning of the reference position of control shaft (14) is performed in a state where the maximum rotation position of control shaft (14) in first rotation direction (R1) is mechanically limited by bringing first movable part (51), which works together with control shaft (14), into an adjacent contact with first stopper (52). First stopper (52) is provided outside the motor housing. Then, the maximum range of the angle of rotation of the control shaft is trained in a state where the position of the maximum rotation of the control shaft in the second direction of rotation is mechanically limited by the second stop.EFFECT: technical result is increased accuracy of detecting the compression ratio of the engine.6 cl, 8 dwg
Patent RU-2715079-C9 (RU)
Inventor: Terashkevich Igor Makarovich
IPC: G01N21/73
Filed: 2019-06-06
Granted: 2020-03-17
Abstract: Использование: для экспресс-анализа элементного состава воды и водных растворов на основе метода эмиссионного спектрального анализа. Сущность изобретения заключается в том, что мобильное устройство для определения примесей в воде и водных растворах содержит электродуговую плазменную горелку, корпус, расположенную внутри него вентиляционную систему, спектрометр, отражающую и фокусирующую систему, консоль, регулируемую платформу для крепления спектрометра, а также отражающей и фокусирующей системы, при этом горелка парожидкостная с функцией возбуждения дугового разряда во встроенном электродном узле при давлении плазмообразующей среды, превышающем атмосферное давление, снабжена заправочной емкостью для плазмообразующей жидкости, причем плазменная струя, являющаяся источником анализируемого излучения, формируется за пределами выходного сопла плазменной горелки. Технический результат: повышение чувствительности, а также расширение функциональных возможностей. 3 з.п. ф-лы, 3 ил.
Patent RU-2735854-C9 (RU)
Title: Model hybrid supercapacitor with pseudo-capacitive electrodes
Inventor: Masalovich Mariya Sergeevna
IPC: H01G11/84
Filed: 2020-05-12
Granted: 2021-04-01
Abstract: FIELD: electrical engineering.SUBSTANCE: invention relates to electrical engineering, particularly to production of electrochemical capacitors with pseudo-capacitive charge accumulation mechanism. Model hybrid supercapacitor with pseudo-capacitive electrodes, including positive and negative electrodes, is characterized by that electrodes are equipped with current collectors in form of stainless steel mesh with deposited on surface of positive electrode layer of cobalt hydroxide and deposited on the surface of the negative electrode of the iron oxide compound, wherein the electrodes are immersed in the electrolyte. Current collectors of positive electrode can be equipped with sublayer of silicon oxide, on top of which there is a layer of cobalt hydroxide. Current collectors of the negative electrode can be equipped with a sublayer of silicon oxide, on top of which a layer of iron oxide compound is applied. Supercapacitor of such design can be used for operation in DC circuits in charge-discharge mode as a power supply for one-time use at rated voltage of 1.4 V and a small number of cycles of order of 10-200.EFFECT: technical result of invention is increase of energy maximum due to maximization of working voltage window.3 cl, 8 dwg, 2 tbl, 2 ex
Patent HU-910176-D0 (HU)
Title: Plant protecting composition containing unsaturated cyclohexyl-acetic acid derivatives and process for producing the active substances
Inventor: MUELLER BERND
IPC: A01N43/40
Filed: 1991-01-18
Abstract: Unsaturated cyclohexylacetic acid derivatives of the formula I <IMAGE>  in which   U is =NOCH3, =CHOCH3, =CH2, =CH-CH3, =CH-CH2-CH3, =N-NH-CH3 or =CH-S-CH3,   n denotes the numbers 0 to 10, A denotes hydrogen or the optionally substituted radicals alkyl, cycloalkyl, aryl or hetaryl, and,   if n = 0, X is a single bond or oxygen or sulphur, and the phytophysiologically acceptable acid addition products and base addition products thereof, and the fungicides and insecticides containing these compounds.
Patent DK-111284-D0 (DK)
Inventor: CHRISTENSEN JOHN MOSGAARD
IPC: D21F11/00
Filed: 1984-02-28
Abstract: PCT No. PCT/DK85/00017 Sec. 371 Date Oct. 28, 1985 Sec. 102(e) Date Oct. 28, 1985 PCT Filed Feb. 27, 1985 PCT Pub. No. WO85/03962 PCT Pub. Date Sep. 12, 1985.A desirable embossing of a fibrous web (6) as dry laid on a forming sheet (2) is effected by the web (6) in a still unglued condition passing a pair of embossing producing rollers (18, 20) carried on or by a pressure resistant support sheet (16) as also passing between the rollers. Problems as to web fractures are hereby widely eliminated.
Patent DK-134691-D0 (DK)
IPC: A61M5/32
Filed: 1991-07-12
Abstract: An insulin injection system comprises a pen shaped syringe with a cartridge containing insulin, and an injection needle, the needle is a thinner than G 29 needle and the insulin is a type which may freely flow through a thinner than G 29 needle. When the insulin is the type comprising suspended crystals the maximal dimension of any crystal is 15  mu m.
Patent DK-287790-D0 (DK)
Inventor: BACH ERIK
IPC: A63H19/22
Filed: 1990-12-04
Abstract: PCT No. PCT/DK91/00375 Sec. 371 Date Jun. 29, 1993 Sec. 102(e) Date Jun. 29, 1993 PCT Filed Dec. 3, 1991 PCT Pub. No. WO92/10259 PCT Pub. Date Jun. 25, 1992.A toy wheel for a model electric train is provided which is formed of two parts axially arranged next to each other. One part of the wheel has a rolling face having a high coefficient of friction for engagement with a track rail. The other part of the wheel is electrically conducting and, in use, engages a side of the track rail. A spring biases the electrically conducting part toward the rolling part and, in use, into electrical engagement with the current carrying rail on which the rolling part rides.
Patent DK-297289-D0 (DK)
Inventor: CORNIE JAMES A
IPC: C22C1/10
Filed: 1989-06-15
Abstract: Composites of materials in which the matrix material does not spontaneously or readily wet the disperse phase and in which the volume fraction of the disperse phase is less than that formed in a packed bed of dispersate particles can be made effectively by an indirect method of infiltrating a packed bed of dispersate particles, using pressure or other mechanical force as needed to overcome poor wetting and form an intermediate concentrated composite. The concentrated composite is then mixed with additional matrix-forming material to produce the finally desired composite. The technique is particularly valuable for composites with ceramic dispersates and metal or alloy matrixes. When the matrix is predominantly aluminum and the dispersates are predominantly silicon carbide, a barrier coating of a material that retards reaction between silicon carbide and alumina is useful.
Patent DK-306690-D0 (DK)
Inventor: TELL ROBERT
IPC: G01J1/44
Filed: 1990-12-28
Abstract: PCT No. PCT/SE89/00404 Sec. 371 Date Mar. 5, 1991 Sec. 102(e) Date Mar. 5, 1991 PCT Filed Jul. 7, 1989 PCT Pub. No. WO90/00732 PCT Pub. Date Jan. 25, 1990.Method and apparatus for spectroscopic measurement of the concentration of a gas in a sample where you detect the intensity of light from a light source (1) passed through the sample (4) and through a reference cell (5) and generates a signal which represents the concentration of the gas. A laser diode (1) constitutes the light source which is locked to the absorption line of the gas at known concentration and pressure contained in a reference cell (5). The laser light with the properly selected wavelength is distributed via optical fibres (2, 3, 6) and/or glass prisms (19, 20) to the reference cell (5) and the sample (4). Non-gas-related transmission variations in the measurement path or in the optics is automatically compensated for by a special laser modulation which generates a time multiplexed reference. The measurement can be performed in a measurement cell incorporating several reflective mirrors (30) to reflect the laser beam several times inside the measurement cell thereby increasing the effective length of the measurement path. The measurement can also be performed using an optical fiber designed so that the surrounding gas or fluid via the evanescent field affects the laser light so that the concentration of the substance in question in the surrrounding fluid or gas can be determined.
Patent DK-342988-D0 (DK)
Inventor: BALLESTER-RODES MONTSERRAT
IPC: C07D277/48
Filed: 1988-06-22
Abstract: It is described the preparation of the famotidine polymorphs with low melting point and relative high or low apparent densities. They differ from the polymorph of high melting point and high density, in the physical-chemical and biological properties, of interest in galenic formulations and preparation of the drug.
Patent DK-350084-D0 (DK)
Inventor: BIETTI GIUSEPPE
IPC: C07D233/84
Filed: 1984-07-17
Abstract: Object of the present invention are new pharmacologically active amidine derivatives of 2-substituted 4-phenylimidazole of formula 
<CHEM>
 in which R representa a linear or branched alkyl group, a hydroxy group, a C1-3 alkoxy group, a mercapto group, C1-3 alkylthio group, a halogen atom, a C1-3 alkylsulfinyl or alkylsulfonyl group, a sulfamoyl group, an amino group which may be substituted by one or two alkyl groups having 1 to 3 carbon atoms, an acylamino group or a phenyl group; R1 and R2, which may be the same or different, represent a hydrogen atom or an alkyl group; R3 represents a linear or branched alkyl group containing optionally one heteroatom such as an oxygen, a sulphur or a nitrogen atom, an alkenyl group, an alkynyl group, a cyano group, an aryl or an aralkyl group optionally substituted, a cycloalkyl or cycloaliphatic alkyl group, a substituted or unsubstituted heterocyclilalkyl or heterocyclic group; R4 represents a hydrogen atom, a C1-3 alkyl or alkoxy group, a halogen atom, a cyano or carbamoyl group, tautomeric forms thereof and acid addition salts thereof. 
<??>Processes for the preparation of the compounds of formula (1) and their intermediates as well as the pharmaceutical compositions containing them are also object of this invention. 
<??>The new compounds are H2-receptor blocking agents which inhibit the gastric acid secretion and are useful antiulcer agents.
Patent DK-355985-D0 (DK)
Inventor: HUCHETTE MICHEL
IPC: C04B24/38
Filed: 1985-08-05
Abstract: 1. Process for the manufacture of gypsum boards, characterized by the fact there is used as a bonding agent protective colloid, an amount of amylaceous material representing from 0.2 to 2 % by weight with respect to the weight of plaster employed, said amylaceous material comprising, on the one hand, a proportion of at least 30 %, preferably at least 45 % by weight of particles of native wheat starch of dimension less than 10.7 mu m and, on the other hand, a proportion of at the most 20 % by weight of particles of native wheat starch of dimension greater than 35 mu m, the presence of these two granulometric fractions being determined by a method A of analysis.
Patent DK-443589-D0 (DK)
Inventor: HANSEN HOLGER CLAUS
IPC: A61P25/20
Filed: 1989-09-08
Abstract: New imidazoquinazoline compounds having the general formula <CHEM> wherein A together with the alpha -marked carbon atom and the  beta -marked nitrogen atom is one of the groups <CHEM> wherein R<4>, R<5>, R<6> and R<7> independently are hydrogen, halogen C1-6-alkyl, aryl or aralkyl R<1> is <CHEM>  cyano or CO2R<8>, wherein R<8> is hydrogen, C1-6-alkyl or C3-7-cycloalkyl, trifluoromethyl or C1-6-alkoxymethyl, R<2> and R<3> independently are hydrogen, halogen, CN, C1-6-alkyl, C2-6-alkenyl, C2-6-alkynyl, trifluoromethyl, C1-6-alkoxy, dialkylaminoalkoxy, aralkoxy, aryloxy which may be substituted with halogen or alkoxy, a cyclic amino group, or NR<9>R<1><0> wherein R<9> and R<1><0> independently are hydrogen or C1-6-alkyl. The compounds are useful in psychopharmaceutical preparations as anticonvulsants, anxiolytics, hypnotics, antipsychotics, antiemetics, or in improving the cognitive function of the brain of mammals.
Patent DK-613089-D0 (DK)
Inventor: ARZBERGER OTTO
IPC: B65D81/20
Filed: 1989-12-06
Abstract: A tear-open can for hermetically enclosable, in particular dry filling material is provided, which consists of a sheet metal body with a bottom formed on in one piece, corresponding to that of a typical drink can, and a sheet metal cover which is firmly connected to the can edge to form a double-fold seam and which has gassing projections in its fold edge and a tear-opening, which is shaped like a sector of a circle, with a grip tongue in its surface.
Patent HU-912253-D0 (HU)
Title: Process for the production of purinyl-phosphonic acid derivatives
Inventor: HALAZY SERGE
IPC: A61P37/06
Filed: 1991-07-03
Abstract: This invention relates to novel purine nucleoside phosphorylase inhibitors, to the methods and intermediates for their preparation and to their use as immunosuppressants, antilymphoma, antileukemic, antiviral and antiprotozoal agents.
Patent HU-896174-D0 (HU)
Title: Process for the preparation of heterocyclic derivatives fusionated 1,2,3,4-tetrahydro-acridine and pharmaceutical compositions thereof
Inventor: SHUTSKE GREGORY MICHAEL
IPC: A61K31/505
Filed: 1989-11-24
Abstract: There are disclosed compounds having the formula <CHEM>  where  R1 is hydrogen, loweralkyl or arylloweralkyl; Z is hydrogen, loweralkyl, loweralkoxy, hydroxy, nitro or trifluoromethyl;  Y is O or NR2, R2 being hydrogen, loweralkyl or arylloweralkyl; and X is CH3, CHR3, C=O, C=S or CHN(CH3)2, R3 being hydrogen, loweralkyl or aryl; or a stereo isomer thereof or a pharmaceutically acceptable acid addition salt thereof, and a process for their preparation. The compounds are useful for the treatment of various memory dysfunctions characterized by decreased cholinergic function, such as Alzheimer's disease, and can therefore be applied as medicaments.
Patent HU-896559-D0 (HU)
Title: Insulating alkenyl aromatic composition
Inventor: SUH KYUNG WON
IPC: B29C48/92
Filed: 1991-04-17
Abstract: Dimensionally stable alkenyl aromatic thermoplastic synthetic resinous elongate foam bodies having closed noninterconnecting gas-containing cells having an average cell size of 0.05 to 2.0 millimeters, a minimum cross-sectional dimension of at least 0.25 inch, a cross-sectional area of at least 8 square inches, a water vapor permeability not greater than 1.8 per inch, a density of from 1.0 to 5.0 pounds per cubic foot (16 to 80 g/l), and an absolute dimensional stability of less than 4 percent in any direction when measured by the test designated ASTM D2126/C578 are prepared using 1,1-difluoro-1-chloroethane as a blowing agent and extruding at controlled temperatures.
Patent NO-872503-D0 (NO)
Inventor: SHADWELL DAVID WILLIAM
IPC: B65D55/02
Filed: 1987-06-16
Abstract: A connection device for two components, for example a container and a dispenser, provided with a member moveable between two positions. In the first position the member permits engagement of the two components. The member moves between the first and second position upon either connection or disconnection of the components and can not be readily moved back to the first position with the member. In the second position the components can not be re-engaged.
Patent NO-892143-D0 (NO)
Inventor: DIEMEER MARTINUS BARNARDUS JOH
IPC: G02F1/01
Filed: 1989-05-26
Abstract: Electro-optical components and semi-manufactured articles, and method for making them. A light conducting layer is formed from a poleable or poled glassy polymer material, which has an under ionizing radiation definitively destructible e/o activity. A selective irradiation under a parallel beam will give sharp transitions (C, D) from an e/o active area (2. 1) or an area which can still be activated to an e/o non-active area. The buffer layers (3 and 5) can also consist of suchlike irradiated material. A suitable positioning of the electrodes (4 and 11) between which by means of a difference in voltage applied across the connections (12 and 13) an electric field with a sufficient intensity and/or uniformity can be induced extending into the border area, on both sides of the transition planes (C, D), will make sharp inducible refractive index transitions possible. This is utilized with e/o inducible waveguides in thin layers to obtain sharp lateral definitions, and in an optical intermediate switch.
Patent NO-892477-D0 (NO)
Inventor: BOOTS GERARDUS ANTHONIUS MARIA
IPC: B65D90/20
Filed: 1989-06-14
Abstract: A container is provided, which comprises a supporting frame including rod-like elements of a relatively rigid, dimensionally stable material, and a flexible sleeve member (14) forming a receptacle for substances, materials, goods and the like to be packaged. The supporting frame includes at least three circumferential walls, a top wall and a bottom wall. A rod-like element is provided at the transition of a circumferential wall to an adjacent circumferential wall. The sleeve member is provided with at least three flexible loop members (15) each extending around a rod-like element and being attached to the sleeve member at two places spaced apart in the circumferential direction of the sleeve member. Each loop member has a length, measured from one place of attachment to the sleeve member to the other, which is a multiple of the circumference of the enveloped rod-like element. The distance between the places of attachment, measured along the sleeve member, is a multiple of the largest transverse dimension of the enveloped rod-like element. The arrangement is such that the loop members keep the sleeve member at all times within the circumference of the frame, at any rate when the sleeve member contains substances, materials, goods or the like.
Patent NO-901440-D0 (NO)
Inventor: CHARMOT DOMINIQUE
IPC: C01G49/00
Filed: 1990-03-29
Abstract: Magnetisable microspheres from 0.05 to 10  mu m in diameter, comprising a core of magnetisable particles and a skin consisting of a hydrophobic crosslinked copolymer derived from a vinylaromatic monomer and from a crosslinking emulsifying polymer. They are obtained by preemulsifying in water a magnetic liquid made up of magnetisable particles dispersed in a vinylaromatic monomer and in a crosslinking emulsifying polymer, polymerisation, separation of the magnetisable microspheres and optional redispersion in water. Use in biology. <IMAGE>
Patent NO-903430-D0 (NO)
Inventor: MATSUBARA KIRA
IPC: A61K31/5377
Filed: 1990-08-03
Abstract: Aminoketone derivative compounds containing a heterocyclic ring bonded to an aminoketone moiety and useful as effective ingredients of centrally acting muscle relaxants and pollakiurea curing agents. They are of formula (I):- <CHEM> s
Patent NO-934772-D0 (NO)
Inventor: BEHRINGER REINHARD
IPC: A23C9/18
Filed: 1993-12-22
Abstract: Milk composition based on the natural constituents of milk and having greatly reduced sodium, potassium and citrate contents. The composition has organoleptic properties which are enhanced with respect to milk, characterised by increased sweetness and a pure and fresh taste, as well as a greater whiteness than that of evaporated milk.
Patent NO-943068-D0 (NO)
Inventor: PIZZI ANTONIO
IPC: C08L97/02
Filed: 1994-08-19
Abstract: Thermocurable binders for cellulose-containing products contain tannin and a substance which liberates formaldehyde at elevated temperature. Materials produced using these binders exhibit good strength properties and low swelling values after immersion in water.
Patent NO-943620-D0 (NO)
Inventor: SCHUSTER ARMIN
IPC: H01B7/18
Filed: 1994-09-29
Abstract: A description is given of a nail clamp (1) for fastening cables and other lines on a surface. In the nail clamp (1), there is provided, in a foot part (2) which exhibits a bearing surface (4) on its underside and a planar clamp surface (5) on its upper side, parallel to the bearing surface, a nail-guiding tube which is perpendicular with respect to the bearing surface (4) and has a nail-guiding duct (7) formed therein. The upper opening of the nail-guiding duct (7) is widened in the form of a flat funnel to form a nail seat (8). In the immediate vicinity of the nail seat there is formed on the foot part (2), on the clamp surface (5), a web-like elevation (12) which, when the nail has been driven in to the full extent, absorbs the majority of the drive-in action and distributes it over the entire foot part. By virtue of this damping of the drive-in action, the nail clamp (1) can be fastened on a surface by nailing without the nail clamp being destroyed. A line grip (3) which is formed on the nail clamp (1), and partially encloses a line and exhibits pointed-cone teeth distributed non-uniformly on its inner side (15), serves for the non-slip connection between nail clamp and the line retained by it. <IMAGE>
Patent NO-953242-D0 (NO)
Inventor: HODGEN GARY D
IPC: A61K31/56
Filed: 1995-08-17
Abstract: The use of a progesterone receptor antagonist for the preparation of a pharmaceutical composition for preventing an oocyte from becoming fertilized without preventing ovulation or interfering with the regularity of the ovarian menstrual cycle of a mammal. <IMAGE>