baber/WOPTO huggingface dataset:
Patent EP-4149528-A1 (EP)
Inventor: SCHIFF RACHEL
IPC: C07K16/28
Filed: 2021-05-12
Abstract: Embodiments of the disclosure include methods and compositions related to treating an individual for HER2+ positive cancer with an appropriate treatment based on outcome of a multiparameter classifier. The methods allow for identification of HER2+ individuals that are suitable to avoid chemotherapy, in specific embodiments. Methods of the disclosure also allow for identification of HER2+ individuals that should not avoid chemotherapy. In specific embodiments, the multiparameter classifier identifies whether there is (1) a ratio of HER2 amplification, relative to a control probe, of greater than or equal to 4.5; (2) a HER2 expression level score of 3+, as determined by immunohistochemistry, in at least 90% of breast cancer cells; (3) whether there is a HER2-enriched molecular subtype; and (4) whether the individual has a wildtype  PIKC3A  gene.
Patent EP-4226560-A1 (EP)
Title: Secondary cell activation using temporary reference signals
Inventor: TAKEDA KAZUKI
IPC: H04L5/00
Filed: 2021-10-01
Abstract: Systems, methods, and devices for secondary cell activation using temporary reference signals are provided. In one aspect, a method of wireless communication performed by a user equipment (UE), includes receiving, from a base station (BS) via a first cell, an activation command to activate a second cell different from the first cell, and receiving, from the BS via the second cell during an activation period, a first reference signal different from a synchronization signal block (SSB). The method further includes performing a measurement of the first reference signal, and operating in the second cell based on the measurement. In some aspects, using reference signals different from SSBs may reduce the delay associated with activating the secondary cell.
Patent EP-4255618-A1 (EP)
Inventor: BAKER ROBERT MILES
IPC: B01J8/02
Filed: 2021-11-12
Abstract: A method is described for shutting down a Fischer-Tropsch reactor fed with a reactant gas mixture comprising a synthesis gas and a recycle gas recovered from the Fischer-Tropsch reactor in a synthesis loop, said Fischer-Tropsch reactor containing a Fischer-Tropsch catalyst cooled indirectly by a coolant under pressure, comprising the steps of: (a) depressurising the coolant to cool the reactant gas mixture to quench Fischer-Tropsch reactions taking place in the Fischer-Tropsch reactor, (b) stopping the synthesis gas feed to the Fischer- Tropsch reactor, and (c) maintaining circulation of the recycle gas through the Fischer-Tropsch reactor during steps (a) and (b) to remove heat from the Fischer-Tropsch reactor. The method safely facilitates a more rapid return to operating conditions than a full shut-down.
Patent EP-4229217-A1 (EP)
Title: Size-based detection and quantification of functional bio-nanoparticles
Inventor: LEBOWITZ MICHAEL S
IPC: C12Q1/6816
Filed: 2021-10-20
Abstract: Sized-based detection techniques for detection of bio-nanoparticles are described. Detection nanoparticles and methods of forming the detection nanoparticles that can be utilized in the techniques are described. Detection nanoparticles can include modified bacteriophage that express a linking agent for a specific binding agent. Detection nanoparticles can bind a functional bio-nanoparticle with high specificity through specific binding of one or more entities unique to the functional bio-nanoparticle of interest. A detection nanoparticle can target an entity of a bio-nanoparticle that is relevant to its function, and as such the methods can provide improvements in detection of complete and functional bio-nanoparticles. Size-based detection regimes can include particle displacement measurement techniques based upon Brownian motion.
Patent EP-4256359-A1 (EP)
Inventor: JENSEN OLE NØRGAARD
IPC: G01R33/46
Filed: 2021-12-02
Abstract: A method of generating a calibrated mathematical function for performing a quantitative determination of nitrogen containing units in a sample is described as well as a method of performing a quantitative determination of nitrogen containing units in a material and/or in a material sample. The function generation method includes generating a set of data of each of M reference samples. The set of data includes at least one N isotope NMR relaxation time and at least one isotope NMR relaxation time. Each set of reference data is associated to known quantity of nitrogen containing units of the respective reference sample. Also a processor having an embedded calibrated mathematical function and a system for performing a quantitative determination of nitrogen containing units is described
Patent EP-4252051-A1 (EP)
Inventor: WU QI
IPC: G02B6/255
Filed: 2021-11-15
Abstract: The present disclosure relates to protecting splices of multiple optical fibers with a low-profile multi-fiber splice protector and a compact splice on furcation housing. The present disclosure also relates to optimal fiber wiring patterns within an optical fiber cable assembly.
Patent EP-4260126-A1 (EP)
Inventor: LE TOUMELIN LOIC
IPC: G02B27/01
Filed: 2021-11-30
Abstract: The present invention relates to a reflection device (100) for a head-up display, to a reflection element assembly (10), to a head-up display and to a motor vehicle, wherein the reflection device (100) is configured for reflecting of radiation emitted by an image generation unit, wherein the reflection device (100) comprises a reflection element (11) having a reflection side (22) and a back side (23) being arranged on the side remote from the reflection side (22), and a carrier (17) supporting the reflection element (11); wherein the reflection element (11) is movably coupled to the carrier (17) by at least one bearing (12A, 12B) such that the reflection element (11) is pivotable relatively to the carrier (17) about at least a first axis (A), wherein the carrier (17) is being couplable to a housing, preferably to a housing of a head-up display, or directly to a vehicle body, and wherein the at least one bearing (12A, 12B) is arranged at the back side (23) of the reflection element such that the first axis (A) is extending completely behind the back side (23) of the reflection element (11).
Patent EP-4260415-A1 (EP)
Title: Method and device for homogenizing the temperature of a laser base plate
Inventor: RUSTEIKA NERIJUS
IPC: H01S3/02
Filed: 2021-12-10
Abstract: The invention relates to the field of laser technology, and more particularly to methods and devices intended for homogenizing the temperature of a laser base plate, wherein optical component holders are attached to the laser base plate, and the laser base plate comprises a heat transfer medium. In order to reduce susceptibility of the laser base plate to local temperature differences, ensuring stable positions of the optical components and, consequently, the orientation of the optical paths, the material from which the laser base plate and optical component holders are made is stainless steel. Passive heat transfer elements are built into the laser base plate and have a significantly higher thermal conductivity than stainless steel, and their coefficient of thermal expansion is close to the coefficient of thermal expansion of stainless steel. The holders of the optical components are attached and adjusted with respect to each other to said laser base plate by means of laser spot welding.
Patent EP-4247804-A1 (EP)
Inventor: BRIZGYS GEDIMINAS J
IPC: C07D401/14
Filed: 2021-11-18
Abstract: The present disclosure provides glucagon-like peptide-1 receptor (GLP-1R) agonists of Formula (l-A), as well as pharmaceutical compositions and therapeutic uses thereof. The compounds are generally useful for treating a GLP-1R mediated disease or condition in a human such as non-alcoholic steatohepatitis (NASH), obesity or type 2 diabetes.
Patent EP-4050944-A1 (EP)
Inventor: ZHAO LIANYI
IPC: H04W24/02
Filed: 2021-06-15
Abstract: Embodiments of this application provide a method for adjusting a quantity of data streams, a terminal, and a MIMO system. In this method, the terminal may actively negotiate the quantity of transport layers used in a downlink data transmission process with a network device based on an operation status of the terminal, so as to adaptively and dynamically adjust the quantity of data streams in the downlink data transmission process. This may reduce power consumption of the terminal and prolong a standby time of the terminal without affecting user experience while meeting requirements for a data transmission rate of the terminal.
Patent EP-4149059-A1 (EP)
Inventor: JIANG LEI
IPC: H04L12/24
Filed: 2021-06-10
Abstract: An alarm mining model determination method and apparatus, a device and a storage medium. Said method comprises: performing mining on training data according to initial full mining parameters to obtain all alarm correlation sets (S101); then, marking a designated alarm according to a rule base and all alarm correlation sets (S102); performing designated alarm mining according to test data and the marked designated alarm (S 103); and if a mining result satisfies a convergence condition, generating an alarm mining model (S104).
Patent EP-4251158-A1 (EP)
Inventor: POLYMEROPOULOS MIHAEL
IPC: A61K31/46
Filed: 2021-11-24
Abstract: L'invention concerne une méthode de traitement ou de prévention de la peur de parler en public (PSA) qui peut, dans certains cas, se présenter sous la forme d'un symptôme d'anxiété sociale (SAD), y compris le sous-type correspondant à la seule représentation (SAD-PO) de la SAD. La méthode de traitement consiste à administrer un agoniste du nAChR α7 tel que le (R)-3-(6-p-tolyl-pyridin-3-yloxy)-1-aza-bicyclo[2.2.2]octane au sujet à raison d'une dose thérapeutiquement efficace.
Patent EP-4173464-A1 (EP)
Inventor: EDO Shunsuke
IPC: A01D46/30
Filed: 2021-06-09
Abstract: The efficiency of work done by an agricultural robot (1) in a facility (100) is improved.An agricultural robot (1) includes a traveling body (3), a working unit (4) to do work relating to a crop (2), the working unit (4) being provided on the traveling body (3), an optical sensor (5A, 5B) provided on the traveling body (3), and a location manager (41C) to determine, based on sensor data obtained by the optical sensor (5A, 5B), whether or not the traveling body (3) is located in a facility (100) for cultivation of the crop (2), and the working unit (4) does the work relating to the crop (2) based on the working unit (4) if the location manager (41C) determines the traveling body (3) as being located in the facility (100).
Patent EP-4177745-A1 (EP)
Title: Resource scheduling method, electronic device, and storage medium
Inventor: JIN SHIYING
IPC: G06F9/54
Filed: 2021-07-02
Abstract: A resource scheduling method, an electronic device, and a storage medium. The embodiments of the present application comprise: obtaining a smart application processing request (S0110); obtaining the current resource usage information (S0120); matching a smart application instance according to the smart application processing request (S0130); and according to the resource usage information and the smart application instance, creating a task to process the smart application processing request (S0140).
Patent EP-4275313-A1 (EP)
Title: Determining overlay codes for transmission of reference signals
Inventor: PEZESHKI HAMED
IPC: H04L5/00
Filed: 2021-12-07
Abstract: Disclosed are techniques for determining tone patterns and associated overlay codes for transmission of reference signals. A tone pattern (e.g., with each tone pattern occupying a resource element in a resource block) can be determined for a reference signal for use in wireless communications between a receiving device and a transmitting device. The tone pattern can include an irregular combination of resource elements in one or more resource blocks for the reference signal. The resource elements can be shared by a plurality of antennas for communication of one or more reference signals between at least the user equipment and the base station. An overlay code may be determined for the tone pattern. Information associated with the transmission of the reference signal using the tone pattern and the overlay code may be communicated by the receiving device.
Patent EP-4179114-A1 (EP)
Title: Sex determination markers in mullets and methods of using thereof
Inventor: RON MICHAEL
IPC: A01K67/02
Filed: 2021-07-07
Abstract: The invention relates to a sex determination (SD) marker of a male Mugilidae fish comprising a nucleic acid sequence corresponding to a sequence of a Follicle-stimulating hormone receptor (FSHR) gene of said fish and including at least one male (Y) specific nucleotide difference when compared to a corresponding sequence on a FSHR gene of a female Mugilidae fish. The invention further concerns uses of this sex determination marker in methods of early sex determination in a Mugilidae fish, methods of sex-reversal of a Mugilidae fish prior to appearance of a sex phenotype, and methods for producing a mono-sex population of Mugilidae fishes.
Patent EP-4181956-A1 (EP)
Inventor: MAHALINGAM SURENDRAN
IPC: A61K39/12
Filed: 2021-07-16
Abstract: This invention relates to a codon deoptimized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome. In particular, embodiments of the invention concern a vaccine comprising live attenuated SARS-CoV-2 comprising a partly codon deoptimized viral genome, SARS-CoV-2 comprising a partly codon deoptimized viral genome, as well as their use in methods of treatment and prevention of viral infection. The ORF1a region of the viral genome has been codon deoptimized.
Patent EP-4268544-A1 (EP)
Title: Lighting state detection for a vehicle trailer
Inventor: KULKARNI CHANDRAKUMAR
IPC: H05B45/50
Filed: 2021-12-13
Abstract: A towing vehicle includes a towing control unit with circuitry to detect whether a light is connected to the electrical harness electrically coupling the vehicle to the trailer. The towing control unit may include lamp connectivity circuits for, for example, the left turn signal and the right turn signal. To determine whether the turn light is connected, the corresponding connectivity circuit periodically generates a test signal. Based on characteristics of a response signal to the test signal. The connectivity circuit determines whether the corresponding turn signal light of the trailer is connected based on a response to the test signal. The connectivity circuit may distinguished whether an incandescent-based turn signal light, a light emitting diode (LED)-based turn signal light, and an open circuit is sensed based on the characteristics of the response signal.
Patent EP-4190131-A1 (EP)
Inventor: ADAMCHUK JENNIFER
IPC: H05K1/09
Filed: 2021-07-26
Abstract: The present disclosure relates to a dielectric substrate that may include a polyimide layer and a first filled polymer layer overlying the polyimide layer. The first filled polymer layer may include a resin matrix component, and a first ceramic filler component. The first ceramic filler component may include a first filler material. The first filler material may further have a mean particle size of at not greater than about 10 microns.
Patent EP-4195849-A1 (EP)
Inventor: Shao Shijia
IPC: H04W72/12
Filed: 2021-08-06
Abstract: The present application provides a configuration method, a communication node, and a storage medium. The configuration method comprises: obtaining transmission indication information; and determining an associated spatial relationship of an uplink control channel corresponding to the transmission indication information during repeated transmission.
Patent EP-4159562-A1 (EP)
Inventor: HU ZHIMIN
IPC: B60W10/06
Filed: 2021-08-18
Abstract: A power distribution management method and device for a hybrid vehicle, the method comprising: receiving accelerator pedal opening information sent by a hybrid vehicle; on the basis of the accelerator pedal opening information, respectively compiling statistics on a first opening change rate when the accelerator pedal opening is in a starting interval and when the accelerator pedal opening is increased and a second opening change rate when the accelerator pedal opening is in an overtaking interval and when the accelerator pedal opening is increased, the starting interval corresponding to a first preset range of the accelerator pedal opening, and the overtaking interval corresponding to a second preset range of the accelerator pedal opening; calculating a driver feature coefficient on the basis of the first opening change rate and the second opening change rate; and sending the driver feature coefficient to the hybrid vehicle. The present application enables the starting of an engine to better meet the requirements of different drivers.
Patent EP-4208850-A1 (EP)
Inventor: KAUFMAN ARIE
IPC: G06T7/00
Filed: 2021-09-01
Abstract: Systems and methods for virtual pancreatography (VP) are disclosed for non- invasive diagnosis and classification of pancreatic lesions. VP is an end-to-end visual diagnosis system that includes: automatic segmentation of the pancreatic gland and the lesions, extraction of the primary pancreatic duct, automatic classification of lesions into a plurality of lesion types, and specialized 3D and 2D exploratory visualizations of the pancreas, lesions and surrounding anatomy. Volume rendering is combined with pancreas and lesion centric visualizations and measurements for effective diagnosis.
Patent EP-4212528-A1 (EP)
Inventor: ZHAN ZHENGYUN
IPC: C07D407/12
Filed: 2021-09-10
Abstract: Disclosed in the present invention are a compound represented by formula Ib or lib, a cis or trans isomer, enantiomer, diastereomer, racemate, tautomer, solvate, hydrate, and pharmaceutically acceptable salt thereof, or a mixture thereof, a pharmaceutical composition containing the compound, and a use of the compound as a GPR40 agonist, wherein n, E, G<sup>1</sup>, L<sup>1</sup>, L<sup>2</sup>, R<sup>1</sup>, R<sup>2</sup>, R<sup>3</sup>, R<sup>4</sup>, R<sup>5</sup>, R<sup>5b</sup>, R<sup>6</sup>, R<sup>7</sup>, X<sup>5</sup>, X<sup>6</sup>, X<sup>7</sup>, Y, Y<sup>1</sup>, Z, Z<sup>1</sup>, and the possible isotopic substitution label of each element in the compound are as defined in the description.
Patent EP-4215750-A1 (EP)
Inventor: WAN LINGLI
IPC: F04C2/10
Filed: 2021-09-14
Abstract: An electronic oil pump (100), comprising a first rotor assembly (2), a stator assembly (4), an electric control board assembly (6), an isolation member (5) and thermal conductive members (9); wherein the first rotor assembly (2) is located in a first chamber (70) of the electronic oil pump (100), the thermal conductive members (9) each comprise a first portion (91) and a second portion (92), the first portions (91) being located in a second chamber (80) of the electronic oil pump (100), the second portions (92) being located in a third chamber (90) of the electronic oil pump (100); wherein the electric control board assembly (6) comprises a base plate (61) and a temperature-sensing unit (13), the base plate (61) comprising first holes (611), an upper plate layer (612), a lower plate layer (613) and at least one metal layer (614), a part of the second portions (612) being located in the first holes (611); wherein the temperature-sensing unit (13) is located at one side of the second portion (92), there is a preset distance between the temperature-sensing unit (13) and the second portion (92); wherein the metal layer (614) closest to the temperature-sensing unit (13) is defined as the closest metal layer (6141), the temperature-sensing unit (13) is projected on the direction parallel to the upper surface of the closest metal layer (6141), at least a part of the projection of the temperature-sensing unit (13) is located on the closest metal layer (6141), the temperature-sensing unit (13) can sense the temperature of the closest metal layer (6141), or the temperature-sensing unit (13) can sense the temperature of the upper plate layer (612) or the lower plate layer (613) in contact with the closest metal layer (6141).
Patent EP-4217040-A1 (EP)
Title: Bendable handheld medical actuator
Inventor: LIMPISVASTI Orr
IPC: A61M25/01
Filed: 2021-09-21
Abstract: A handheld medical device (10) with a distal implement (12) is disclosed. The handheld rotary medical device (10) may include an inner drive shaft (14), an elongated, tubular, outer housing (16) encapsulating the inner drive shaft (14) such that the inner drive shaft (14) is positioned within the outer housing (16). The inner drive shaft (14) may include one or more inner drive shaft bendable sections (18), and the outer housing (16) may include one or more outer housing bendable sections (20). The inner drive shaft bendable section (18) may be heated to anneal the material forming the inner drive shaft bendable section (18) such that during use the inner drive shaft bendable section (18) may be bent into a desired position and, once bent, the inner drive shaft bendable section (18) remains in the desired position and does not bind against the elongated, tubular, outer housing (16).
Patent EP-4228797-A1 (EP)
Inventor: PANDIT ANIRUDDH
IPC: B01J4/00
Filed: 2021-10-15
Abstract: Provided are systems and methods for collecting and storing a microbiome-derived gaseous sample.
Patent EP-4234607-A1 (EP)
Inventor: HWANG DA-YOUNG
IPC: C08G63/60
Filed: 2021-09-14
Abstract: The present disclosure relates to a method for preparation of a polyester copolymer including recycled monomers, and to a method for preparation of a polyester copolymer having excellent quality while using recycled monomers.
Patent EP-4232074-A1 (EP)
Inventor: LOW PHILIP S
IPC: A61K38/22
Filed: 2021-08-26
Abstract: Osteotropic ligand-bone anabolic agent compounds and related compositions and methods of use to treat bone fractures.
Patent EP-4254118-A1 (EP)
Inventor: GOTO AYUMU
IPC: G05D1/02
Filed: 2021-11-24
Abstract: A mobile body system (100) including: a mobile body (110); and a time route calculation system (120) that calculates a time route from a starting position to a target position of the mobile body (110). The time route includes points on a route and times when the mobile body (110) is present at the points. The time route calculation system includes: a node information set obtainer (121) that obtains a node information set of a plurality of node information items each of which includes point information and time information, where the point information indicates, in an identifiable manner, a plurality of points arranged in a virtual area for a corresponding one of times at predetermined intervals, and the time information indicates the corresponding one of the times; a search space creator (122) that obtains link information linking two of the plurality of node information items, to create a search space; a search space updater (123) that changes the link information to an impossible value to update the search space, where the link information determines, based on the time route of a given mobile body, that the given mobile body will come in contact with the mobile body, and the impossible value indicates that moving is impossible; and a route determiner (124) that determines the time route of the next mobile body based on the updated search space.
Patent EP-4253444-A1 (EP)
Inventor: PAI JAE YOUNG
IPC: C08G18/38
Filed: 2021-11-25
Abstract: A polythiol composition according to exemplary embodiments includes a first polythiol compound which provides a maximum peak in a high performance liquid chromatography (HPLC) analysis graph obtained at a wavelength of 230 nm, and a second polythiol compound having a molecular weight greater than that of the first polythiol compound and represented by C 9 H 20 S 6 . A ratio of a peak area of the second polythiol compound to a peak area of the first polythiol compound, which are measured through the HPLC analysis graph at the wavelength of 230 nm, is 0.05 to 5.0%.