baber/WOPTO huggingface dataset:
Patent WO-2020167996-A1 (WO)
Inventor: KERAVALA ANNAHITA
IPC: C07K14/705
Filed: 2020-02-12
Abstract: La présente invention concerne des vecteurs de thérapie génique comprenant une séquence polynucléotidique codant pour un polypeptide LAMP-2, leurs procédés d'utilisation, des compositions pharmaceutiques, etc,. En particulier, l'invention concerne des vecteurs AAV recombinés ayant un sérotype AAVrh74 exprimant LAMP-2A, LAMP-2B ou LAMP-2C pour une utilisation comme agent thérapeutique, par exemple, la maladie de Danon.
Patent WO-2020180573-A1 (WO)
Inventor: RIOS CARLOS A
IPC: H04B7/10
Filed: 2020-02-26
Abstract: Methods and apparatus for orthogonal stream spatial multiplexing. In one embodiment, a method includes splitting and modulating a data stream into n MIMO RF spatial streams and coupling them to corresponding switchable polarization antenna elements controlled via orthogonal binary codes for transmission. Each transmitted stream manifests as time-varying-polarization-orthogonal to the other n-1 spatial streams. The method includes reception of the streams at their destination using corresponding antenna elements controlled by the same set of orthogonal codes. Thus, each of the n transmitted spatial streams is polarization-match-filtered, unambiguously separated and individually recovered from all the others upon reception for subsequent demodulation and MIMO spatial recombination into the original data stream. Thus, n MIMO spatial streams emanating from a common source and featuring equal amplitude and bandwidth but bearing distinct data and exhibiting mutually orthogonal time varying polarization will propagate mutually interference-free on the same frequency channel to a single destination.
Patent WO-2020214365-A1 (WO)
Title: Power-based decoding of data received over an optical communication path
Inventor: HASSAN AMER AREF
IPC: H04L25/49
Filed: 2020-03-25
Abstract: A system for transmitting data over an optical communication path is configured to receive data to be encoded in a bitstream for transmission using an optical communication path and encodes the received data to obtain a bitstream. The system is further configured to determine that the bitstream includes a sequence of consecutive bits, and obtain a power level at which to transmit a portion of the bitstream based on a count of the consecutive bits in the sequence. The system may be configured to selectively activate a light source at a power level according to a modulation scheme to optically transmit the portion of the bitstream at the power level.
Patent WO-2020205675-A1 (WO)
Title: Memristive multi-terminal spiking neuron
Inventor: CHO HANS
IPC: H01L45/00
Filed: 2020-03-28
Abstract: A memristive multi-terminal spiking neuron apparatus, comprising a non-volatile memristor, wherein the non- volatile memristor has a resistance ratio between the high-resistance and low-resistance states exceeding (4) decades of magnitude, wherein the non-volatile memristor retains its resistance states for a time period exceeding (1) second, a volatile memristor, wherein the volatile memristor retains its low-resistance state for a time period of less than (10) nanoseconds, and a capacitor, wherein the volatile memristor is in parallel with the capacitor. A method of making a programmable electrical spiking output from a memristive multi-terminal spiking neuron, comprising providing one or more devices wherein each device comprises a non-volatile memristor, a volatile memristor, wherein the volatile memristor is in parallel with the capacitor, providing a first input spiking signal to a neuron device, providing a second input spiking signal, and creating a programmable spiking output signal which changes.
Patent WO-2020210169-A1 (WO)
Inventor: SHYKIND DAVID NATHAN
IPC: A61K9/00
Filed: 2020-04-06
Abstract: An apparatus that is µm- or nm-scale in size and can include integrated circuitry logic based on sub 10nm SIA transistor nodes, a sensing subsystem, a deciding subsystem, an effecting subsystem, and a power harvesting system is described. The sensing subsystem can identify pathogenic entities, including disease associated cells (for example, cancer cells, autoimmune cells, or pathological microbes) or viruses. The sensing subsystem can include at least one pad constructed of an electrically conductive material and linkers attached to the at least one pad. Each linker can also be attached to a targeting agent (for example, an antibody fragment) or a reference agent. Upon the binding of a targeting agent with an entity of interest, the information is transferred to the logic circuitry, which processes the binding event information and decides whether the entity is disease associated (e.g., a disease associated cell or virus) and requires delivery of therapeutic agents or other treatment.
Patent WO-2020214463-A1 (WO)
Title: Fibrotic ventricular tissue disruption
Inventor: KARAPETIAN EMIL
IPC: A61B17/22
Filed: 2020-04-08
Abstract: A process of disrupting fibrotic ventricular tissue involves advancing a compliant balloon device (50) to a ventricle (3) of a heart using a delivery catheter (60), expanding the compliant balloon device to contact target tissue associated with fibrotic tissue (25,26) of the ventricle, and further expanding the compliant balloon device to an expanded state to disrupt the target fibrotic tissue.
Patent WO-2020214935-A1 (WO)
Inventor: HUANG MISTY
IPC: C08G18/24
Filed: 2020-04-17
Abstract: An alkoxysilyl-containing polyurethane polymer composition is prepared using a urethane-forming organometallic catalyst which is then stabilized to moisture exposure by the addition of a mercapto-containing compound. The stabilized moisture-curable alkoxsilyl-containing polyurethane polymer composition is activated to moisture curing by the addition of a hydrolysis and condensation catalysts. The stabilized moisture-curable alkoxsilyl-containing polyurethane polymer composition is useful as a component in the preparation of coatings, adhesives, sealants, consumer goods and industrial goods.
Patent WO-2020263417-A1 (WO)
Inventor: TAYLOR JOHN ANTHONY
IPC: H04L12/58
Filed: 2020-05-04
Abstract: The present disclosure relates to processing operations configured to generate and present a chat bot diagnostic visualization that provides real-time visual insights into operation of a chat bot for debugging assistance. A chat bot diagnostic tool is programmed to launch a graphical user interface that displays a visual representation of diagnostic data for debugging a chat bot in real-time. To enable conversational specific data to be reviewed, the present disclosure is configured to implement a middleware adapter within in a run-time stack of a chat bot that is configured to trace data traffic between a chat bot and a channel of an application/service. This enables the chat bot diagnostic tool to observe data traffic and filter the data traffic to identify relevant data for debugging a chat bot. A debugging data visualization of a chat bot interaction is emulated through a graphical user interface of the chat bot diagnostic tool.
Patent WO-2020227595-A1 (WO)
Inventor: AFTAB BLAKE
IPC: C07K14/725
Filed: 2020-05-08
Abstract: Disclosed are compositions and methods for targeted treatment of cancer, such as hepatocellular carcinoma. In particular, chimeric antigen receptor (CAR) T cells are disclosed that can be used with adoptive cell transfer to target and kill cancer cells with reduced antigen escape. Therefore, also disclosed are methods of providing an anti-tumor immunity in a subject with hepatocellular carcinoma that involves adoptive transfer of the disclosed CAR T cells.
Patent WO-2020237058-A1 (WO)
Title: Dispositifs de saisie et leurs procédés de fabrication
Inventor: HOLMES DOUGLAS P
IPC: B25J15/06
Filed: 2020-05-21
Abstract: L'invention concerne un dispositif comprenant une pluralité de fentes ménagées selon un certain motif, une pluralité de parties de charnière, deux parties de mâchoire opposées, et deux pattes d'actionnement opposées. Les deux pattes d'actionnement opposées sont conçues pour se déplacer dans des sens globalement opposés d'une première position vers une seconde position en réponse à une entrée pour aider à amener les deux parties de mâchoire opposées à saisir un objet.
Patent WO-2021011122-A1 (WO)
Inventor: Bibliowicz Arieh
IPC: G06F21/62
Filed: 2020-06-09
Abstract: Methods, systems and computer program products are provided for cloud-based data access control. Data sensitivity levels are assigned to data. User sensitivity levels are assigned to users. A query sensitivity level to data may be dynamically calculated for a query during query processing. User access to the data may be determined by comparing the calculated query sensitivity level to a user sensitivity level. A query result for the query may be provided to a user that has a user sensitivity level equal to or greater than the query sensitivity level, while a modified or alternate query result (e.g., empty set) may be provided to the user if the user sensitivity level is lower than the query sensitivity level.
Patent WO-2020252193-A1 (WO)
Title: Optical eyepiece using single-sided patterning of grating couplers
Inventor: LUO KANG
IPC: G02B6/34
Filed: 2020-06-11
Abstract: An eyepiece includes a substrate and an in-coupling grating patterned on a single side of the substrate. A first grating coupler is patterned on the single side of the substrate and has a first grating pattern. The first grating coupler is optically coupled to the in-coupling grating. A second grating coupler is patterned on the single side of the substrate adjacent to the first grating coupler. The second grating coupler has a second grating pattern different from the first grating pattern. The second grating coupler is optically coupled to the in-coupling grating.
Patent WO-2020257462-A1 (WO)
Inventor: DUAN SUSU
IPC: A61K38/37
Filed: 2020-06-18
Abstract: Disclosed herein are methods of treating subjects with hemophilia and low bone mineral density (BMD) with a chimeric protein comprising a coagulation factor and a Fc domain. In certain embodiments, the chimeric protein is rFVIIIFc. In certain embodiments, a subject to be treated has hemophilia A.
Patent WO-2021007361-A1 (WO)
Title: Constructions de protéine de liaison à l'antigène et utilisations de celles-ci
Inventor: NICHOLS ALEXANDER
IPC: C07K16/28
Filed: 2020-07-08
Abstract: L'invention concerne des constructions de protéine de liaison à l'antigène aptes à la liaison spécifique de CD22 ou d'un épitope de CD22 presenté sur la surface d'une cellule de mammifère cible, ladite liaison d'antigène étant fonction du pH. L'invention concerne également des utilisations de ces constructions de protéine de liaison à l'antigène.
Patent WO-2021040959-A1 (WO)
Inventor: SIMON ANDREAS
IPC: B66F9/06
Filed: 2020-07-30
Abstract: A method for operating a materials handling vehicle (10) is provided comprising: monitoring, by a controller (103), a first vehicle drive parameter corresponding to a first direction of travel of the vehicle during a first manual operation of the vehicle by an operator and concurrently monitoring, by the controller, a second vehicle drive parameter corresponding to a second direction different from the first direction of travel during the first manual operation of the vehicle by an operator. The controller receives, after the first manual operation of the vehicle, a request to implement a first semi-automated driving operation. Based on the first and second monitored vehicle drive parameters during the first manual operation, the controller controls implementation of the first semi-automated driving operation.
Patent WO-2021026098-A1 (WO)
Title: Inhibiteurs de kif18a
Inventor: TAMAYO NURIA A
IPC: C07D405/12
Filed: 2020-08-03
Abstract: L'invention concerne des composés amide de formule (I) : et des compositions les contenant, et des procédés de préparation de tels composés. L'invention concerne également des procédés de traitement de troubles ou de maladies pouvant être traités par inhibition de la protéine du moteur de la kinésine KIF18A, tels que le cancer, le psoriasis, la dermatite atopique, un trouble auto-immun, ou une maladie intestinale inflammatoire, et analogues.
Patent WO-2021030345-A1 (WO)
Inventor: YE ZHENG
IPC: F04D25/06
Filed: 2020-08-11
Abstract: A submersible well fluid pump (12) has diffusers (41) non-rotatably mounted in a pump housing (21). A drive shaft (29) rotates an impeller (43) between each of the diffusers. A bearing (45) is positioned between and in abutment with two of the diffusers. An annular recess (55) encircles an outer wall (61) of the bearing. A wave spring (85) has undulations with inward protruding indentations (93) in contact with a base (86) of the recess and outward protruding indentations (91) in engagement with an inner wall (27) of the housing. The wave spring is split and radially compressed between the base of the recess and the housing inner wall.
Patent WO-2021066993-A1 (WO)
Inventor: JOHN BRIAN HENRY
IPC: G06F1/14
Filed: 2020-09-02
Abstract: An artificial reality system includes a head-mounted display (HMD) configured to output artificial reality content, wherein the HMD includes a first wireless transceiver to communicate with one or more devices of the artificial reality system; a peripheral device of the one or more devices of the artificial reality system configured to capture media samples for the HMD to output the artificial reality content, wherein the peripheral device includes a second wireless transceiver to communicate with the HMD; a clock manager of the HMD configured to compute a first delta between a timestamp of the HMD and a timestamp of the first wireless transceiver; and a clock manager of the peripheral device configured to compute a second delta between a timestamp of the peripheral device and a timestamp of the second wireless transceiver, wherein the first delta and the second delta are used to adjust a clock of the peripheral device.
Patent WO-2021055325-A1 (WO)
Title: Rapid dispersal formulation containing a sulfopolymer
Inventor: PONASIK JAMES
IPC: A01N25/04
Filed: 2020-09-15
Abstract: The present disclosure describes a composition including a sulfopolymer, and one or more agrochemicals. The composition exhibits improved dispersal and/or re-dispersal characteristics as compared to the same composition without the sulfopolymer. The present disclosure also describes methods of making and using such formulations in agriculture.
Patent WO-2021061765-A1 (WO)
Inventor: ROSTAMI-HODJEGAN AMIN
IPC: C12Q1/6883
Filed: 2020-09-23
Abstract: An assay method is provided for determining the status of the health of a tissue within the body of a subject, wherein the tissue comprises an abundance of at least a first target protein, wherein assay comprises analysis of a liquid biopsy sample obtained from the subject, and wherein the liquid biopsy sample comprises at least a first cell free mRNA (cf-mRNA) that encodes the at least a first target protein. The assays and methods are useful in the diagnosis and treatment of liver health in a subject. In particular, methods and systems are provided for the diagnosis and treatment of fatty liver; non-alcoholic steatohepatitis (NASH); cirrhosis; liver disease; hepatitis; and liver cancer.
Patent WO-2022066160-A1 (WO)
Title: Continuous processes for the selective conversion of aldohexose-yielding carbohydrate to ethylene glycol using low concentrations of retro-aldol catalyst
Inventor: SCHRECK DAVID JAMES
IPC: C07C29/12
Filed: 2020-09-24
Abstract: Retro-aldol processes are disclosed that use very low concentrations of retro-aldol catalyst in combination with hydrogenation catalyst of certain activities, sizes and spatial dispersions to obtain the high selectivities to ethylene glycol.
Patent WO-2021067268-A1 (WO)
Inventor: PEPE PAUL JOHN
IPC: G02B6/44
Filed: 2020-09-29
Abstract: A high density coupling panel of the present disclosure presents a compact grouping of coupler wherein each of the couplers couples a first free connector with a second free connector wherein each of the free connectors is coupled to exactly two electrical conductors. The high density coupling panel can be manufactured in a shielded (e.g., metal) or non-shielded (e.g. non-metal) form as appropriate to a specific application. In the shielded configuration, a bonding strip is used to connect all metal components (e.g., shielded free connectors, shielded couplers, and metal panel of the high density coupling panel) to ground via a shielding tab.
Patent WO-2021101625-A1 (WO)
Inventor: SEMENOV BORIS
IPC: H02P5/74
Filed: 2020-09-29
Abstract: A power control system is provided for AC mains, including an input bridge rectifier connected to the AC power mains, and a buck regulator circuit connected to the DC output of the input bridge rectifier, the output of the buck regulator circuit providing a DC power output bus. A current sensor is connected to the output of the buck regulator circuit, and one or more capacitors is connected across the DC power output bus for receiving current from the buck regulator circuit. The buck regulator circuit is controlled to limit peak output current thereof.
Patent WO-2021067362-A1 (WO)
Inventor: CUI ZHENJIANG
IPC: H01L21/3213
Filed: 2020-09-30
Abstract: Exemplary methods for selectively etching cobalt-containing material from a substrate may include forming a plasma of a carbon-containing precursor in a substrate processing region housing the substrate. The substrate may include exposed cobalt-containing material. The methods may include forming a conformal carbon-containing film on the exposed cobalt-containing material. The methods may include forming a local plasma of a hydrogen-containing precursor and removing a portion of the carbon-containing film to expose at least a portion of a surface of the cobalt-containing material. The methods may include forming a local plasma of a chlorine-containing precursor and contacting the exposed portion of the surface of the cobalt-containing material with chlorine-containing plasma effluents to form cobalt chloride complexes. The methods may include flowing a nitrogen-containing precursor into the processing region and contacting the cobalt chloride complexes with the nitrogen-containing precursor. The methods may include recessing the surface of the cobalt-containing material.
Patent WO-2021072132-A1 (WO)
Title: Cassette for dispensing pleated tubing
Inventor: DUNN STEVEN BRYAN
IPC: B65B67/12
Filed: 2020-10-08
Abstract: A cassette to dispense a pleated tubing. The cassette includes a circular body having an annular channel housing with a central cylindrical core. At least one wall has an upper end with a lip disposed thereon. An annular cover is attached to the lip at the upper end defining a gap over the annular body. A tubing is disposed within the annular channel housing and withdrawn from the gap. At least one of a plurality of apertures is provided at a lower end of the annular channel housing. The apertures have reinforced walls. The apertures are adapted to be aligned with a projection extending upward from within a container.
Patent WO-2022093169-A1 (WO)
Title: Media holders
Inventor: LORENTE TEJERO VICTOR
IPC: B41J11/00
Filed: 2020-10-26
Abstract: An apparatus is disclosed herein. The apparatus comprises a carriage to move laterally in a scanning direction over a platen, a scan beam to support the carriage over the platen, a mechanism to move the scan beam vertically, and a media holder. The media holder comprises a central portion to hold a media on the platen, a first end couplable to the platen at a coupling position, and a second end couplable to the scan beam such that the second end moves vertically along with the scan beam.
Patent WO-2021108077-A1 (WO)
Inventor: GU YONGBIN
IPC: G06F12/08
Filed: 2020-10-30
Abstract: A system for fetching data for an accelerator that include detecting an attempt to access a first page of data that is not stored on a primary storage unit of the accelerator, wherein the first page of data corresponds to part of an array with a number of dimensions; and responsive to detecting the attempt to access the first page of data: dividing the array into sub-arrays by: dividing the array into a number of 1st level sub-arrays, and dividing a first 1st level sub-array into a number of 2nd level sub-arrays; selecting pages for prefetching includes selecting all pages in a first 2nd level sub-array for prefetching and transferring the first page of data and any pages of data selected for prefetching from a memory system connected to the accelerator into the primary storage unit
Patent WO-2021091787-A1 (WO)
Inventor: BROTHERTON KIENAN
IPC: B65G47/91
Filed: 2020-10-30
Abstract: Disclosed embodiments include an apparatus for reducing contamination or obstruction of a multi-directional flow filtration system. As one example, a scalper that is to be employed on a multi-directional flow filtration system comprises a body and a set of scalping walls forming a plurality of helical chambers, the set of scalping walls helically extending along at least a portion of an interior of the body in a longitudinal direction. In this way, the plurality of helical chambers may enable the multi-directional flow filtration system to passively scalp contaminants in a manner that improves overall operation of the multi-directional flow filtration system. Other embodiments may be described and/or claimed.
Patent WO-2021108111-A1 (WO)
Title: Passer des sauts de fréquence de liaison descendante dans une bande de fréquences non autorisée
Inventor: LIU CHIH-HAO
IPC: H04W72/04
Filed: 2020-11-09
Abstract: La divulgation concerne des systèmes, des procédés et un appareil, y compris des programmes informatiques codés sur des supports de stockage informatiques, pour des communications à bande étroite au moyen de sauts de fréquence. Dans certains modes de réalisation, un équipement utilisateur (UE) peut recevoir un signal de référence de découverte (DRS) comprenant un signal invitant à passer un saut identifiant au moins un UE, peut rester sur un canal d'ancrage lorsque le signal invitant à passer un saut identifie l'UE, et peut commuter du canal d'ancrage à un premier canal de saut de liaison descendante (DL) d'un motif de saut de fréquence DL lorsque le signal n'identifie pas l'UE. Dans certains autres modes de réalisation, une station de base (BS) peut être configurée pour produire un DRS comprenant un signal invitant à passer un saut identifiant au moins un UE, pour produire un signal indiquant un temps d'occupation de canal (COT) obtenu sur un premier canal de saut DL d'un motif de saut de fréquence DL, et pour produire des données DL sur le premier canal de saut DL du motif de saut de fréquence DL.
Patent WO-2021097215-A1 (WO)
Title: Devices, systems and methods to remove blood clots
Inventor: KRELL PAUL
IPC: A61B17/22
Filed: 2020-11-13
Abstract: A device or system (100) for removing a blood clot (10) from a blood vessel (12) includes an elongate intravascular element (27) having a non-expandable distal end portion (27a). At least one hole (23) fluidically connects an interior lumen (27b) of the elongate intravascular element (27) with an exterior of the elongate intravascular element (27). The at least one hole (23) is located proximal to the distal end portion (27a). The distal end portion (27a) is configured to sealingly engage an interior wall surface (12a) of the blood vessel (12) and occlude the blood vessel (12).