baber/WOPTO huggingface dataset:
Patent IL-172869-A0 (IL)
Title: Human antibody molecules for il-13
IPC: A61P1/00
Filed: 2005-12-28
Abstract: There are described recombinant VH and VL domains of human antibodies that bind IL-13. A series of proteins characterised by three CDR in each VH/VL are described. Preferably the molecules are single chain Fv or antibody molecules. Nucleic acids expressing the VH and VL domains are selected from phage display libraries. Neutralization potency of the resulting scFv's was tested in TF proliferation assays. The fragments and antibodies showed efficacy for IL-13 binding in murine models of pulmonary inflammation, the primate (cynomolgus) model of dermal allergy, IgE release from B cells and histamine potentiation in Ca2+ signalling in smooth muscle. Mice transgenic for human IL-13 antibodies and epitope mapping studies are also described. It is envisaged that the anti 11-13 reagents may be used to treat asthma, atopic dermatitis, allergic rhinitis, fibrosis, IBS, or Hodgkin's lymphoma.
Patent IL-179469-A0 (IL)
Title: Device, system and method of mounting audio/video capturing equipment
IPC: H04N5/775
Filed: 2006-11-21
Abstract: Some embodiments of the invention include devices, systems and methods of mounting audio/video capturing equipment. For example, a mounting device for mounting equipment onto a helmet includes: a support structure having one or more gripping mechanisms adapted to be fitted to one or more locations of the helmet; and a camera mount, at a first location of the support structure, to support a camera at a desired image-capturing position.
Patent IL-191166-A0 (IL)
Title: Modified colorants and inkjet ink compositions comprising modified colorants
IPC: C09D7/62
Filed: 2008-04-30
Abstract: The present invention relates to a modified colorant comprising a colorant having attached at least one organic group. Various embodiments of the organic group are disclosed. For each of these embodiments, preferably the organic group has a defined calcium index value. Also disclosed are various uses for these modified colorants, including inkjet ink compositions.
Patent IL-192295-A0 (IL)
Title: Bis--platinum complexes with antitumor activity
Filed: 2008-06-19
Abstract: A compound of general formula (I): in which: R is selected from the group consisting of (C1-C25)alkyl, (C2-C25)alkenyl, aryl, (C7-C10)aralkyl; n and m are each independently an integer of two to eight; p is one or two; A is selected from the group consisting of -B-, -B-(CH2)r-B-, -B-(CH2)r-B-(CH2)z-B-, wherein r and z are an integer from 2 to 8, B is a -NR1- or -N(R2)2+1/pQ-p group, in which R1 is selected from hydrogen, (C1-C4)alkyl, (C1-C4)acyl, tert-butoxycarbonyl, and R2 is selected from hydrogen and (C1-C4)alkyl; Q-p is an anion selected from chloride, bromide, iodide, nitrate, sulphate, hydrogen sulphate, perchlorate, R3COO- wherein R3 has the same meanings as R, independently from one another and R4-O-SO3- wherein R4 is (C2-C14)alkyl with the proviso that, when Q-p is selected from chloride, bromide, iodide, nitrate, sulphate, hydrogen sulphate, perchlorate, R is not (C1-C4)alkyl.
Patent IL-206444-A0 (IL)
Title: Process for the resolution of isoquinoline derivatives
Filed: 2010-06-17
Abstract: A process for the resolution of racemic tetrahydropapaverine with optically active arylpropionic acids is described.
Patent RO-127541-A0 (RO)
Title: Hydraulic cutter for cutting tubing and packers
Inventor: STOICA LUCIAN
IPC: E21B29/08
Filed: 2011-12-21
Abstract: The invention relates to a hydraulic cutter for cutting tubing or a mechanical or hydraulic packer equipping an oil and/or gas extraction well, that cannot be extracted at the surface. According to the invention, the cutter comprises a supporting ring (7) and a recovering spring (6) for restoring a piston (4) to the initial position, between a launching reduction gear (2) and a piston (4) there being confined a circulation chamber (g), and inside a hollow body (1) there being confined an outletting chamber (a) which establishes the circulation communication between some communication orifices (b) provided in a pressing bushing (8) and the two external communication orifices (c) in the hollow body (1), to the lower side of the body (1) there existing a window (e) wherein there are located some cutting elements (10) which present at the upper side a profile (h) allowing the embedding and accommodating the pressing bushing (8) in a recess (d), fixed with an axle (9) to the body (1) an which are maintained closed by an elastic element (11).
Patent RO-137439-A0 (RO)
Title: Manufacturing process and ultra-fast dissolving softgel capsule
Inventor: BUZILA-STANCU SEVERIN-ANDREI
IPC: A61K8/11
Filed: 2023-01-06
Abstract: The invention relates to a process for preparing water-soluble biodegradable gelatin-based capsules for packaging personal care bath cosmetic products. According to the invention, the process consists of the following steps: mixing 25...40.84% gelatin with 25...40.84% water in a 1:1 ratio and with 10...16.34% glycerin in a tight mixer, at a temperature of 60°C, dosing the mixture in the form of a semi-wet roll, introducing 0.001...20% enzyme granules of bromelain, papain and actinidin type and up to 40% sodium chloride and 4.97% acetylsalicylic acid, respectively, by spraying, during the formation of the network, thus maintaining more than 95% of the added ingredients in their dry form, encapsulating the cosmetic product with the generation of the spherical shape, drying the capsules, applying, by bombardment in a mixer, a moisture-protection coating layer of up to 0.4 μm from siloxane solution in admixture with calcium, resulting in capsules having dissolution properties in contact with the water jet of up to 2 seconds, i.e. quick access to the cosmetic product.
Patent MA-19365-A1 (MA)
IPC: C06B47/04
Filed: 1982-01-04
Abstract: Water-bearing explosives comprising oxidizer, fuel, and sensitizer components in a thickened or gelled continuous aqueous phase are stabilized against the degradation of their thickened or gelled structure by the incorporation therein of iodide and/or iodate ions. Preferably, iodide ion is introduced by dissolving ammonium iodide or an alkali metal iodide in an aqueous liquor or sol containing the oxidizer component. The stabilization method is particularly useful in explosives containing a guar gum thickener and flake aluminium in the sensitizer component.
Patent MA-20919-A1 (MA)
IPC: A61P25/28
Filed: 1987-03-25
Abstract: The invention relates to novel compounds having a nootropic activity, the use of ACE inhibitors as medicaments having nootropic activity, agents containing them, and their use in the treatment and prophylaxis of cognitive malfunctions.
Patent MA-21944-A1 (MA)
Inventor: H J LANG
IPC: C07C311/15
Filed: 1990-09-05
Abstract: Benzoylguanidines of the formula I  (* CHEMICAL STRUCTURE *) (I) where R(1) or R(2) is equal to R(6)-S(O)n- or R(7)R(8)N-O2S- and the other substituent R(1) or R(2) is in each case equal to H, F, Cl, Br, I, alkyl, alkoxy or phenoxy, R(6)-S(O)n or R(7)R(8)N- and R(6) is equal to alkyl, cycloalkyl, cyclopentylmethyl, cyclohexylmethyl or phenyl, R(7) and R(8) are equal to alkyl or phenylalkyl or phenyl, and in which R(7) and R(8) may also together be a C4-C7 chain, and in which R(7) and R(8), together with the nitrogen atom to which they are bonded, may be a dihydroindole, tetrahydroquinoline or tetrahydroisoquinoline system, and where R(3), R(4) and R(5) are equal to hydrogen or alkyl, or R(3) and R(4) are together an alkylene chain or R(4) and R(4) are together an alkylene chain, and where n is equal to zero, 1 or 2 and their pharmaceutically tolerable salts are outstanding antiarrhythmics.
Patent MA-23997-A1 (MA)
Inventor: VOLPI SYLVAIN
IPC: D06B3/26
Filed: 1996-10-25
Abstract: The apparatus (1) for processing textile materials in a movable vat (2) bath, such as for dyeing, has a rapid connection (4) to a fixed technical supply and control station (3). It has at least one general control unit (18) with controls (14-17) and operating unit (12) for the treatment fluid(s). The operating unit ensures that the recirculating fluid is maintained at nominal levels of flow, pressure and temperature from its supply to the vat connection. Preferably the supply station has a number of rapid connections, for simultaneous links to a number of vats. The operating units have at least one fluid circulation circuit and a circulation pump (12), to fill and empty the circuit with the treatment fluid(s) and additives. The control system sets the bath feed and the bath level in the vat, temperature, and the pH value. The control has an electronic circuit (18) to maintain the set parameters for each vat and its batch. A colorimeter (17) monitors the recirculating bath in one of the outlet channels (22) or the input channel (13) to the pump (12).
Patent MA-44193-A1 (MA)
Title: Procédé de détection du vol d'une installation photovoltaïque.
Inventor: EL OUAHABI MOHAMED
IPC: G01R31/40
Filed: 2018-12-11
Abstract: L'invention concerne un procédé de détection de vol des installations photovoltaïques basé sur des capteurs de courant sans contact. Ce procédé économique permet une protection efficace des installations.
Patent MA-52672-A1 (MA)
Title: Nouveau procédé de synthèse d'oxyde de germanium en milieu acide
Inventor: BENZAKOUR INTISSAR
IPC: C22B41/00
Filed: 2021-02-26
Abstract: La présente invention décrit un nouveau procédé hydrométallurgique permettant la synthèse d’oxyde de germanium (geo2), en milieu acide, à partir d’une matière contenant le ge (un minerai de zinc, un co-précipité d’hydroxyde de fe/ge ou un ferroalliage). Ledit procédé comporte les étapes suivantes: a) pré-concentration du ge à partir de la matière contenant le ge, b) lixiviation du pré-concentré ge obtenu à l’étape (a), c) séparation de la solution de lixiviation de son résidu solide, d) acidification de la solution de lixiviation issue de l’étape (c), e) séparation de la solution acidifiée du précipité obtenu à l’étape (d). Le produit issu de ce procédé est constitué de grains de geo2 cristallisés avec une teneur en germanium supérieure à 50 %, de taille homogène et de forme cubique ou pseudo-cubique, comme le montre l’image meb de la figure ci-dessous
Patent UY-23251-A1 (UY)
Inventor: IBANEZ PALOMEQUE FRANCISCO
IPC: H04M3/22
Filed: 1991-06-28
Abstract: Such comprising the intrinsic cooperation between a messages concentration unit, a central operating unit, various display screens, printers, information storage devices including operating and management software, in order that modular telephones and validation and identification units and access units, together with the regional invoicing centres and the validation and invoicing centre, and the terminals of collector firms, by exchanging various specific operating messages within the modular public telephone management system, control all the context and operations stemming from their performance. <IMAGE>
Patent UY-26462-A1 (UY)
Title: Procedimiento para la fabricación de recipientes de doble capa para la extracción de líquidos.
Inventor: STROETMANN ULRICH
Filed: 2000-11-30
Abstract: Procedimiento para fabricar recipientes, compuesto de un recipiente exterior rígido, esencialmente con estabilidad de forma, y un recipiente interior fácilmente deformable (recipiente de doble capa), unido al recipiente exterior de manera que un líquido en su interior puede ser aspirado totalmente mediante aplicación de depresión, por ejemplo por medio de un tubo ascendente. Preferentemente, el recipiente interior está unido fijamente al recipiente exterior en la zona de la boca y en la zona del fondo.
Patent UY-29403-A1 (UY)
Title: Composiciones farmacéutica sólida que comprende telitromicina.
Inventor: CHRISTIAN DESESQUELLE
IPC: A61K9/20
Filed: 2006-02-24
Abstract: Se divulga una composición farmacéutica sólida que comprende telitromicina o una de sus sales de adición con un ácido farmacéuticamente aceptable según una proporción en telitromicina comprendida entre 0,1 y 80% en peso, como principio activo, y al menos un agente diluyente con comportamiento plástico, según una proporción de 10 a 50% en peso, con respecto al peso total de la composición. Proporciona ventajosamente un comprimido de telitromicina que tiene un tamano sensiblemente reducido, a dosis por tanto igual de telitromicina, y que presenta propiedades mecánicas mejoradas.
Patent UY-31360-A1 (UY)
Title: Peptidos y polipeptidos permeabilizadores de celulas para celulas microbianas
Inventor: JOHN KELLY WILLIAM
IPC: A61K31/7052
Filed: 2008-09-25
Abstract: La invención abarca péptidos senal y polipéptidos que comprenden estos péptidos, así como polinucleótidos que codifican estos péptidos o poliléptidos. La invención también presenta vectores de expresión que comprenden estos polinucleótidos y células huésped que comprenden estos vectores. La invención da a conocer además composiciones y métodos para la detección, selección como blanco, permeabilización e inhibición de células microbianas, especialmente células metanógenas, utilizando los péptidos, polipéptidos, polinucleótidos, vectores de expresión o células huésped descriptos.
Patent ES-181708-A1 (ES)
Title: MEJORAS EN LA CONSTRUCCIoN DE OTOMANES DOBLES
Filed: 1948-01-15
Abstract: Mejoras en la construcción de otomanas dobles en que la otomana inferior son unidas entre si por un mecanismo que al transferir la otomana superior a la posición de acostarse transmite un movimiento elevador a dos brazos a modo de tijeras en la otomana inferior de manera que ambas superficies para acostarse ocupen la misma altura, estando guiado, en cada par de brazos de tijera en la otomana inferior, el extremo superior de un brazo por un eje en una ranura horizontal en la otomana inferior y estando conectado el último con la otomana superior mediante dos pares de miembros portadores paralelos o aproximadamente paralelos, mientras que un extremo de un miembro conectador está conectado giratoriamente con dicho eje y el otro extremo está conectado giratoriamente con dicho eje y el otro extremo está conectado giratoriamente con el brazo posterior en cada par de miembros portadores a alguna distancia del punto de giro conectador de este miembro con la otomana inferior, caracterizadas por ser la otomana superior en ambos extremos algo más larga que la otomana inferior y por estar provista de cuatro patas individuales con el fin de hacer posible por ello que la otomana superior sea desconectada de la otomana inferior y que ambas puedan utilizarse como camas individuales.
Patent ES-183278-A1 (ES)
Title: UN CáTODO, INDIRECTAMENTE CALENTADO, PARA VáLVULAS TERMOIoNICAS
Filed: 1948-04-14
Abstract: Cátodo calentado indirectamente con una superficie emisora sustancialmente plana el cual se sostiene sobre o por un órgano u órganos de material cerámico o refractario.
Patent ES-183813-A1 (ES)
Title: Perfeccionamientos introducidos en los rectificadores de valor de mercurio.
IPC: H01J13/16
Filed: 1948-05-22
Abstract: Perfeccionamientos introducidos en los rectificadores de vapor de mercurio, caracterizados especialmente por el hecho de que el ánodo está subdividido en cierto número de secciones, quedando común la estructura de rejilla y pantalla, asegurando unos dispositivos igualadores de corriente una distribución uniforme de la corriente, en las diferentes secciones.
Patent ES-192714-A1 (ES)
Title: Una maquina para descabezar pescado
Filed: 1950-04-26
Abstract: Máquina para descabezar pescado caracterizada porque está compuesta principalmente de dos cuchillas guillotinas que colocadas a ambos extremos de una mesa donde se deposita el pescado y accionadas por un motor eléctrico tienen un movimiento de vaivén y descabezan el pescado automáticamente con solo introducirlo debajo de ellas.
Patent ES-193364-A1 (ES)
Title: SOPORTE PARA VáLVULAS ELECTRoNICAS DE LA SERIE RIMLOCK
Filed: 1950-06-12
Abstract: Soporte para válvulas electrónicas de la serie "Rimlock" caracterizado por estar compuesto de tres planchas superpuestas de las que la primera constituye el alojamiento y soporte de las patillas de contacto la segunda constituye la plaqueta de separación de las patillas y la tercera la plaqueta tapa y guía para las patillas de la lámpara.
Patent ES-253768-A1 (ES)
Title: Polymerization catalysts and their use in the polymerization of unsaturated hydrocarbons
IPC: C08F4/00
Filed: 1959-11-27
Abstract: A polymerization catalyst comprises a compound of a metal of Group I, II or III of the Periodic Table according to Mendel<\>aeeff in which the metal is bound to nitrogen atoms and in which no metal-to-carbon or covalent metal-to-hydrogen bonds are present, together with a compound of a transition metal of Group IV, V, VI, VII or VIII of the Table. Preferred compounds are those having the general formula Xn Me [N (R1 R2)]m wherein Me is beryllium, lithium, magnesium or aluminium, R1 and R2 are the same or different and represent alkyl, cycloalkyl, aryl or alkylaryl groups or, conjointly with the nitrogen atom form a heterocyclic ring, X is chlorine, bromine or iodine, n is zero or an integer, m is an integer, and n+m is the valency of the metal Me. Specified compounds are: aluminium-tris (diphenylamide), magnesium diphenylamide bromide, aluminium bis (diphenylamide) chloride, magnesium (diethylamide) bromide, aluminium tris (N-carbazyl), aluminium bis (diphenylamide) bromide, aluminium bis (diethylamide) monochloride, aluminium tris diethylamide, bis (magnesium iodide) phenylamide, and aluminium nitride. The second compound may be TiCl3, CoCl3, Ti(OC3H7)4, CrCl3 or VCl3.ALSO:A polymerization catalyst comprises a compound of a metal of Group I, II or III of the Periodic Table according to Mendel<\>aeef in which the metal is bound to nitrogen atoms and in which no metal-to-carbon or covalent metal-to-hydrogen bonds are present, together with a compound of a transition metal of Group IV, V, VI, VII or VIII of the Table. Preferred compounds are those having the general formula XnMe[N(R1R2)]m wherein Me is beryllium, lithium, magnesium or aluminium, R1 and R2 are the same or different and represent alkyl, cycloalkyl, aryl or alkylaryl groups or, conjointly with the nitrogen atom form a heterocyclic ring, X is chlorine, bromine or iodine, n is zero or an integer, m is an integer, and n+m is the valency of the metal Me. Specified compounds are aluminium-tris(diphenylamide), magnesium diphenylamide bromide, aluminium bis(diphenylamide) chloride, magnesium (diethylamide) bromide, aluminium tris(N-carbazyl), aluminium bis(diphenylamide) bromide, aluminium bis(diethylamide) monochloride, aluminium tris diethylamide, bis(magnesium iodide) phenylamide, and aluminium nitride. The second compound may be TiCl3, CoCl3, Ti(OC3H7)4, CrCl3 or VCl3. The catalyst may be used for the polymerization of ethylene, propylene or butadiene.ALSO:Magnesium diphenylamide bromide is reacted with AlCl3 to give aluminium trisdiphenylamide. The latter compound may be reacted with AlCl3 to give aluminium bis(diphenylamide) chloride, or with AlBr3 to give the corresponding bromide. Aluminium tris-diethylamide is prepared from AlCl3 and magnesium diethylamide bromide the product may be reacted with AlCl3 to give aluminium bis(diethylamide) chloride. Aluminium tris(N-carbazyl) is prepared from AlEt3 and carbazole.
Patent ES-257219-A1 (ES)
Title: Organosilicon compounds
IPC: C07F7/08
Filed: 1960-04-08
Abstract: Methylpolysiloxanes are produced from tetramethylsilane by reacting it with sulphuric acid and hydrolysing the product with water. At least 1 mol, preferably 4-20 mol of sulphuric acid are used per mol of tetramethylsilane. The reaction temperature is below 120 DEG C. to produce hexamethyldisiloxane and in the range 120 DEG -200 DEG C. to produce higher polysiloxanes. The tetramethylsilane and sulphuric acid may be heated together in a vessel equipped for distillation, or the mixture may be passed down a heated packed column. Removal of two or three methyl groups may be carried out in one operation or, after the removal of the first methyl group, the hexamethyldisiloxane produced may be further reacted with sulphuric acid followed by hydrolysis to give methylpolsiloxanes. In Example 1 tetramethylsilane and sulphuric acid are reacted at 20 DEG C., the reaction mixture is diluted with water and extracted with ether: the ether is removed by distillation to give hexamethyldisiloxane. In Examples 2-6 varying proportions of tetramethylsilane and sulphuric acid are reacted at 125 DEG -130 DEG C. to give dimethylpolysiloxanes. The products of Examples 5 and 6 were equilibrated in the presence of a little aqueous potassium hydroxide. In Example 7 the mixture of tetramethylsilane and sulphuric acid is passed down a column packed with porcelain rings and heated at 125 DEG C. further sulphuric acid is passed down the column and the combined sulphuric acid solution is hydrolysed. In Example 8 the column is heated at 130 DEG C. the product is equilibrated to give a rubbery elastomer. In Examples 9 and 10 the column is heated at 80 DEG C. and the products are hexamethyldisiloxane containing a little hexamethylcyclotrisiloxane.
Patent ES-292713-A1 (ES)
Title: Joint assembly
IPC: E04B1/58
Filed: 1963-10-19
Abstract: Two metal members 1 of angle section are connected together by an L-shaped member 5 having arms of L-shaped cross-section and spring plates 9. Each plate 9 has ends 8, 10 bent at angles greater than a right angle. In Fig. 4 the spring plates clamp the member 5 against inturned flanges 3 on the members 1. In Fig. 8 the spring plate 9 clamps the member 5 and the member 11 of angle section inside a connecting member of angle section having inturned flanges 3, 4. The member 5 and the spring plate are of steel and the angle members of aluminium. This joint is shown between members holding the edges of panels, Fig. 9, 10 (not shown).
Patent ES-335165-A1 (ES)
Title: Process and apparatus for producing phosphoric acid from phosphate rock
IPC: C01B25/225
Filed: 1967-01-02
Abstract: The invention of Specification 1,175,421 is modified by mixing phosphoric acid with phosphate rock before the latter is added to the cyclic flow path.
Patent ES-335548-A1 (ES)
Title: New Peroxyesters and uses thereof
IPC: C08F4/32
Filed: 1967-01-12
Abstract: Carboxylic peresters (a) of formula where R and R1 are monovalent tertiary hydrocarbyl groups, and X and Y are hydrocarbyl groups, same or different, unsubstituted or substituted, (b) with a cyclic structure in which R and R1 are replaced by R11, a divalent ditertiary hydrocarbyl group which may be substituted or unsubstituted and (c) with polymeric structure of receiving units are prepared by reacting the corresponding acyl halides with tert. hydroperoxides e.g. t.butyl hydroperoxide or 2,5-dimethyl-2,5-diperoxyhexane, preferably in the presence of an inert solvent and a basic agent, or by other conventional methods. Di-t-butyl peroxy diglycollate, di-t-butylperoxy oxydipropionate, di-t-butylperoxy oxydi (4-benzoate), cyclic-(2,5-dimethyl-2,5-diperoxyhexane diglycollate, and poly-(2,5-dimethyl-2,5- diperoxyhexane diglycollate are claimed. The products may be as catalysts in addition polymerization processes.