Patent FR-2961100-A1 (FR)
Title: Use of 2-pyrrolidone compounds as a cosmetic active solubilization agent including assets of care for the keratin fibers
Inventor: DUBLANCHET ANNE-CLAUDE
IPC: A61K8/49
Filed: 2010-06-09
Abstract: Use of one or more 2-pyrrolidone compounds (I) as a cosmetic active solubilization agent including assets of care for the keratin fibers, and their organic or mineral acid or base salts, optical isomers, stereoisomers or enantiomers and diastereomers, geometric isomers, tautomers, and solvates such as hydrates, is claimed. Use of one or more 2-pyrrolidone compounds of formula (I) as a cosmetic active solubilization agent including assets of care for the keratin fibers, and their organic or mineral acid or base salts, optical isomers, stereoisomers or enantiomers and diastereomers, geometric isomers, tautomers, and solvates such as hydrates, is claimed. X : O or a divalent amino group of formula (-N(R5)-); R5 : H, 1-30C alkyl, preferably 1-6C alkyl, optionally substituted by one or more -OH, -SH, -NH 2, tri(1-6C) alkyl ammonium, or cationic heteroaryl, such as pyridinium, imidazolium, and/or guanidinium; R1, R2 : saturated linear 1-12C, branched 3-12C or cyclic 3-7C hydrocarbon chain (optionally substituted by (-N +>R7R8R9)), where the hydrocarbon chain is interrupted by (i) one or more heteroatoms of O-, -N (R6) or -S-, and/or (ii) one or more -S(O)-, -S(O) 2-, -C(O)-, -N +>(R6)(R7)-, preferably -N(R6)-C(O)-, -C (O)-N(R6)-, -N(R6)-C(O)-N(R7)- or -S-S- and/or optionally (iii) optionally saturated 3-6 membered ring optionally substituted by one or more groups of OH or -NRR1a, divalent chain of formula (-cycl-Alk-cycl1-), or unsaturated linear 2-12C, branched 3-12C or cyclic 3-7C hydrocarbon chain (-N +>(R7)(R8)(R9)) (optionally substituted), where the hydrocarbon chain is interrupted by (i) one or more heteroatoms of O-, -N(R6) or -S-, and/or (ii) one or more -S(O)-, -S(O) 2-, -C(O)-, -N +>(R6)(R7)-, preferably -N(R6)-C(O)-, -C(O)-NR6-, -NR6-C(O) -NR7- or -S-S- and/or optionally (iii) optionally saturated 3-6 membered ring optionally substituted by one or more groups of OH or -NRR1a (all optionally substituted by one or more pyrrolidin-2-one group of formula (E) or (F)); cycl, cycl1 : cyclic hydrocarbon chain, preferably 5-6C cycloalkylene such as cyclohexylene or cyclopentylene; Alk : optionally substituted 1-6C alkylene chain, preferably unsubstituted; X1a : -O- or -N(R5)-; R1a, R2a : saturated linear 1-12C, branched 3-12C or cyclic 3-7C hydrocarbon chain (-N +>(R7)(R8)(R9)) (optionally substituted), where the hydrocarbon chain is interrupted by (i) one or more heteroatoms of O-, -N (R6) or -S-, and/or (ii) one or more -S(O)-, -S(O) 2-, -C(O)-, -N +>(R6)(R7)-, preferably -N(R6)-C(O)-, -C (O)-N(R6)-, -N(R6)-C(O)-N(R7)- or -S-S- and/or optionally (iii) optionally saturated 3-6 membered ring optionally substituted by one or more groups of OH or -NRR1a, divalent chain of formula (-cycl-Alk-cycl1-), or unsaturated linear 2-12C, branched 3-12C or cyclic 3-7C hydrocarbon chain (-N +>(R7)(R8)(R9)) (optionally substituted), where the hydrocarbon chain is interrupted by (i) one or more heteroatoms of O-, -N(R6) or -S-, and/or (ii) one or more -S(O)-, -S(O) 2-, -C(O)-, -N +>(R6)(R7)-, preferably -N(R6)-C(O)-, -C(O)-NR6-, -NR6-C(O) -NR7- or -S-S- and/or optionally (iii) optionally saturated 3-6 membered ring optionally substituted by one or more groups of OH or -NRR1a, where R2 and/or R2a represents a bond; A1, A2 : H, OH, SH, ONR7R8, -O-P(O)(OH) 2, -O-S(OH) 2OH, SO 2OH, COOH, 3-8 membered (hetero)cycle (optionally saturated and optionally substituted by one or more OH-1-6C alkyl, OH or -NRR1a, and the (hetero) cycle can be cationic), ammonium group of formula (-N +>(R7)(R8)(R9)), guanidine group of formula (RR1aN-C(=NR2a)-N(R4a)-), preferably H 2N-C(=NH)-NH-, guanidinium group of formula (RR1aN-C(=N +>R2aR3a)-N(R4a)-), pyrrolidin-2-one group of formula (G) or (H); Xaa : -O- or -NR5-; R1aa, R2aa : R1a; R3, R3a, R4, R4a, R5, R3aa, R4aa : H, 1-12C linear alkyl chain or 3-12C branched alkyl chain; R6 : H, 1-20C linear alkyl or 3-12C branched alkyl, optionally substituted by group (G) or (H); R7-R9 : H or 1-6C alkyl optionally substituted by one or more OH; or NR7R8, NR8R9, NR7R9 : cationic or non cationic 4-7 membered heterocycle, preferably cationic heteroaryl optionally substituted by one or more 1-6C alkyl optionally substituted by one or more OH; and R, R1a, R2a, R3a : H or 1-18C alkyl optionally substituted by one or more OH, provided that when A1, A2, R1, R2, and/or R5 contain or designate a cationic group, then the electroneutrality of (I) is provided by an anionic counter ion or its mixture. Independent claims are included for: (1) cosmetic composition comprising: (I); and one or more active care; and (2) process for treating keratin materials, comprising application of, to the keratin material, (I) and applying one or more assets of care or applying the cosmetic composition. [Image] [Image].