baber/WOPTO huggingface dataset:
Patent NZ-624015-A (NZ)
Title: Methods and products for treatment of diseases
Inventor: BAR-OR DAVID
IPC: A61P7/10
Filed: 2010-06-22
Abstract: The disclosure provides a method of treating a disease or condition mediated by vascular hyperpermeability in an animal. The method comprises administering an amount of a danazol compound effective to inhibit vascular hyperpermeability and an amount of a second drug effective to treat the disease or condition. The disclosure further provides a method of inhibiting vascular hyperpermeability when it is a side effect caused by administration of a drug to, or another treatment of, an animal. The method comprises administration of an amount of a danazol compound effective to inhibit the vascular hyperpermeability. The disclosure also provides a method of modulating the cytoskeleton of endothelial cells in an animal comprising administering an amount of a danazol compound and an amount of a second drug effective to modulate the cytoskeleton. The present disclosure also relates to pharmaceutical compositions and kits comprising a danazol compound and a second drug.
Patent NZ-629720-A (NZ)
Title: Knockout for use while necking a metal container, die system for necking a metal container and method of making a metal container
Inventor: DICK ROBERT E
IPC: B30B15/02
Filed: 2013-12-10
Abstract: A punch, necking or knockout die system for creating a neck in a metal or plastic bottle or container is described. The container includes multiple inner diameters which accommodate a bulge in the inner necking or knockout die, which adds a flaring effect to the bottleneck when removed from the closed container. The system includes: an external necking die (see figure 1); a container (100) with first and second inner diameters (220 and 240 respectively); and an inner knockout die with outer diameters (300 and 320 respectively) that accommodate the inner diameters of the container. Optionally, the first diameter is at least 0.001 inches larger than the second, but must always be larger.
Patent NZ-706316-A (NZ)
Title: Single serve capsule comprising a filter element connected thereto by sealing
Inventor: KRÜGER MARC
IPC: B65D85/804
Filed: 2013-09-27
Abstract: Single serve capsules according to the prior art have the disadvantage that the produced beverage displays comparatively more foam on its surface. Foaming is substantially reduced by the single serve capsule of the present invention which provides a single serve capsule for preparing a beverage, comprising a side wall and a bottom, which together define a space, a filter element being sealed to the bottom within said space. In particular, the present invention provides a single serve capsule (1) for producing a beverage, having a side wall (1.2) and a base (1.1) which collectively define a space (1.7), wherein within the space (1.7) a filter element (2) is sealed to the base (1.1), wherein the sealing seam (7) is provided so as to be toroidal and the outer diameter (L1) of the sealing seam is 75 to 85% of the diameter (L3) of the filter element (2), characterized in that the inner diameter (L1) of the sealing seam is 67 to 77% of the diameter (L3) of the filter element (2).
Patent NZ-712088-A (NZ)
Title: Fluid evacuation device
Inventor: GREEP DARCY
IPC: A61M1/00
Filed: 2014-03-14
Abstract: Modern surgical techniques typically employ radio frequency power to cut tissue and coagulate bleeding encountered in performing surgical procedures. When an electrosurgical instrument is used for cutting or coagulation, smoke is commonly produced. As a result, combination electrosurgical instrument and smoke evacuation devices have been developed. The components of the combination devices have flexibility, weight, and resistance drawbacks. This is compounded when procedures are performed on sensitive parts of the body that require precision and accuracy. The present disclosure provides a fluid evacuation device that is attachable to a hand-held instrument to provide the hand-held instrument with fluid evacuation capabilities. The fluid evacuation device includes a nozzle, a hose mount, and a flexible evacuation hose. The nozzle has a receptacle that receives a portion of a hand-held instrument therein. The distal end of the nozzle has an opening therein through which fluid may be drawn into the nozzle. The fluid can pass through a flow region in the nozzle. The hose mount extends from the proximal end of the nozzle. The hose mount includes a passageway through which the fluid can pass from the flow region into the flexible evacuation hose. The flexible evacuation hose has a first section and a second section. A swivel is connected between the first section and the second section to enable relative rotation between the first section and the second section. The swivel reduces rotational torque. One or more fasteners connect the evacuation hose and the power cable, such that the connected length of the evacuation hose and the power cable extends away from the hand-held instrument at a location between the proximal and distal ends of the hand-held instrument. Securing the cable and the evacuation hose together in this manner reduces the resistance typically created by the cable.
Patent NZ-714530-A (NZ)
Title: Serpina1 irna compositions and methods of use thereof
Inventor: BETTENCOURT BRIAN
IPC: A61P1/16
Filed: 2014-05-22
Abstract: The invention relates to RNAi agents, methods of using such RNAi agents to inhibit expression of Serpina1, and methods of treating subjects having a Serpina1 associated disease, such as a liver disorder. The RNAi agent of the invention targets the Serpina1 gene, and is a double stranded RNAi made up of an antisense strand and a sense strand, wherein substantially all of the nucleotides of both strands are modified, at least one strand is attached to a ligand, and wherein the antisense strand comprises at least 19 contiguous nucleotides differing by no more than 3 nucleotides from the nucleotide sequence of 5’ – UUUUGUUCAAUCAUUAAGAAGAC – 3’ (SEQ ID No: 419).
Patent NZ-719672-A (NZ)
Title: Tripeptide compositions and methods for treatment of diabetes
Inventor: CHEN YUQING
IPC: A61P3/10
Filed: 2012-02-10
Abstract: Disclosed is an oral dosage form comprising as the sole active product ingredient, at least one peptide consisting of the amino acid sequence GGL, GLL, GGdL, GdLL, GLdL or GdLdL, or a pharmaceutically acceptable salt of the peptide, and a pharmaceutically acceptable excipient.
Patent NZ-719996-A (NZ)
Title: Electrotherapy device
Inventor: RAMI MURILLO XAVIER
IPC: A61N1/08
Filed: 2014-11-28
Abstract: The invention relates to an electrotherapy device comprising: a plurality of active electrodes; a return electrode; and a plurality of voltage generators which are each connected to an active electrode; wherein said device comprises a controller for the voltage generators, which is provided with means for monitoring and/or varying the voltage supplied to each one of the active electrodes independently.
Patent NZ-720483-A (NZ)
Title: Water-dispersible plant growth regulating concentrate and processes for making and using same
Inventor: WIKELEY PHIL
IPC: A01N25/04
Filed: 2014-12-09
Abstract: Water-dispersible plant growth regulating compositions in concentrated suspended particle form with an approximately neutral pH (6-8). The compositions comprise a cytokinin, a surfactant, an anti-foam agent, a buffering system, an anti-freeze agent, a biocide, and an anti-settling system, dispersed in water. The cytokinin is in an amount from 0.1 to 80 wt.% and has a particle size of 1-5 µm.
Patent NZ-724366-A (NZ)
Title: Compositions and methods for modulating complement factor b expression
Inventor: SWAYZE ERIC E
IPC: C12N5/00
Filed: 2015-05-01
Abstract: The present embodiments provide methods, compounds, and compositions for treating, preventing, or ameliorating a disease associated with dysregulation of the complement alternative pathway by administering a Complement Factor B (CFB) specific inhibitor to a subject.
Patent NZ-724869-A (NZ)
Title: Insulin-like growth factor 1 receptor -specific antibodies and uses thereof
Inventor: STANIMIROVIC DANICA
IPC: C12N15/13
Filed: 2014-12-04
Abstract: The blood-brain barrier (BBB) prevents transport of molecules larger than 500 Daltons from blood to brain. Receptor-mediated transcytosis (RMT) facilitates transport across the BBB of specific molecules that bind receptors on brain endothelial cells that form the BBB. An insulin-like growth factor 1 receptor (IGF1R)-binding antibody or fragment thereof is identified that transmigrates the BBB by RMT. The antibody or fragment is used to deliver a cargo molecule across the BBB, wherein the cargo molecule may be a therapeutic or detectable agent. The antibody is a camelid VHH, prepared by immunizing a llama with a 933-amino acid IGF1R polypeptide. Humanized forms of the camelid VHH are also generated.
Patent NZ-726418-A (NZ)
Title: Secure, motor-driven hinge to be provided on a humanoid robot
Inventor: CLERC VINCENT
IPC: F16D49/20
Filed: 2015-06-05
Abstract: The invention relates to a secured motorized articulation intended to be mounted between a first and a second limb of a humanoid-type robot, in order to improve the safety of use of the humanoid robot, and meet the relative emerging regulatory requirements, the second motorized articulation comprising: a motor (21) comprising a fixed part (25) intended to be linked to the first limb, and a mobile part (26) that can be moved relative to the fixed part (25) and intended to be linked to the second limb relative to the first limb, a brake (22) capable of exerting a force on the mobile part (26) of the motor (21) by spring effect, to prevent the movement of the mobile part (26) relative to the fixed part (25), an actuator (23) capable of displacing the brake (22) by opposing the spring effect, so as to release the mobile part (26) of the motor (25) from the force of the brake (22) and allow the motor (21) to move the mobile part (26) relative to the fixed part (25) wherein the motor (21) is a rotary electric motor, the fixed part comprising a base pad (25) and the mobile part comprising a shaft that can be driven in rotation relative to the base pad (25) and a bell housing (26) secured to the shaft, and the brake (22) comprises a shoe (50) that can be displaced between a secured position, in which the shoe in contact with the bell housing (26) exerts a force on the bell housing (26) to prevent, by friction, the rotation of the shaft relative to the base pad (25), and an operational position, in which the shoe is separated from the bell housing (26), releasing the shaft from the force of the brake (22), and wherein the bell housing (26) consists of a metal material and is of substantially cylindrical form, and the shoe (50) consists of an elastomer material and is configured to come into contact with the bell housing (26) along a radial section of the bell housing (26).
Patent NZ-730012-A (NZ)
Title: Compounds and compositions for modulating egfr mutant kinase activities
Inventor: LEE JAEKYOO
IPC: C07D413/14
Filed: 2015-10-13
Abstract: The present invention provides a new group of protein kinase inhibitors, aminopyrimidine derivatives, and pharmaceutically acceptable salts thereof that are useful for treating cell proliferative disease and disorder such as cancer and immune disease. The present invention provides methods for synthesizing and administering the protein kinase inhibitor compounds. The present invention also provides pharmaceutical formulations comprising at least one of the protein kinase inhibitor compounds together with a pharmaceutically acceptable carrier, diluent or excipient therefore. The invention also provides useful intermediates generated during the syntheses of the aminopyrimidine derivatives.
Patent NZ-739235-A (NZ)
Title: Rotary cutter unit
Inventor: HAVERS THOMAS
IPC: A01D75/18
Filed: 2016-06-17
Abstract: A rotary cutter unit for an agricultural mower comprising a housing (14) that carries a rotary bearing (18) and a rotor assembly. The rotor assembly includes a shaft (24) extending through the bearing, a drive input element (28) at an input end of the shaft and a drive output element (32) at an output end (22) of the shaft. A frangible element (40) comprising a weakened portion of the shaft (24) is provided between the drive input element and the drive output element. The frangible element is configured to break when subjected to an excessive load to interrupt the transmission of rotary drive between the drive input element and the drive output element. The rotary cutter unit further provides a retention mechanism, including a retention element (46, 48) that extends substantially radially between the drive output element (32) and the housing (14) to restrict axial movement between the drive output element and the housing. The retention mechanism prevents separation of the drive output element from the housing when the frangible element breaks but permits rotation of the drive output element relative to the housing. The invention mitigates loose disc issues that occur in known rotary cutters with a frangible shaft, and is more reliable than shear pin mechanisms.
Patent NZ-749346-A (NZ)
Title: Imidazo[1,2-a]pyridine derivatives, methods for preparing the same and use thereof
Inventor: LEE HYUNHO
IPC: C07D471/04
Filed: 2017-07-04
Abstract: The present disclosure relates to novel imidazo[1,2-a]pyridine derivatives, and more particularly to imidazo[1,2-a]pyridine derivatives having an excellent activity of inhibiting gastric acid secretion, methods for preparing the same, and the use thereof. The imidazo[1,2-a]pyridine derivatives according to the present disclosure have gastric acid secretion inhibitory activity, and thus may be effectively used for the prevention or treatment of gastrointestinal inflammatory diseases or gastric acid-related diseases.
Patent NZ-755991-A (NZ)
Title: Calcium carbonate slurry
Inventor: YANG ROBERT
IPC: B24B1/00
Filed: 2018-02-21
Abstract: A composition for use in polishing a substrate is provided that comprises a calcium carbonate slurry. The calcium carbonate slurry comprises a plurality of calcium carbonate particles having an average diameter between about 10 nm to 3 µm suspended in a solution, where the solution consists of i) water, a buffer, or combinations thereof; ii) a dispersant selected from the group consisting of sodium polyacrylate, sodium n-silicate, sodium tetrapyrophosphate, sodium hexametaphosphate, sodium polyalluminate, sodium tetraborate, sodium triphosphate, sodium citrate, and combinations thereof; iii) a surfactant selected from the group consisting of sodium dodecyl sulfate (SDS), polysorbate, octylphenol ethoxylate, and combinations thereof, and iv) an optional chelating agent. The concentration of the calcium carbonate particles in the calcium carbonate slurry is equal to or less than about 2.0 wt.%, and the concentration of the dispersant in the calcium carbonate slurry ranges from about 0.1 wt.% and 0.5 wt.%
Patent NZ-789568-A (NZ)
Title: Apparatus for controlling fluid flow
Inventor: KAMEN DEAN
IPC: A61M5/168
Filed: 2012-12-21
Abstract: A flow meter, comprising: a coupler adapted to couple to a drip chamber; a support member operatively coupled to the coupler; a modulatable backlight assembly configured to provide a first backlight and a second backlight; an image sensor having a field of view and operatively coupled to the support member, wherein the image sensor is configured to view the drip chamber within the field of view and the modulatable backlight assembly; and at least one processor operatively coupled to the image sensor and the modulatable backlight assembly, wherein: the at least one processor receives data from the image sensor having at least a portion of the modulatable backlight assembly represented therein, and the at least one processor is configured to modulate the backlight assembly to the first backlight when estimating a drop size and to modulate the backlight assembly to the second backlight.
Patent PT-100777-A (PT)
Inventor: PELOSI STANFORD SALVATORE JR
IPC: C07D405/12
Filed: 1992-08-14
Abstract: The novel 4-oxocyclic ureas and the pharmaceutically- acceptable salts and esters thereof of the present invention are useful as antiarrhythmic and antifibrillatory agents and have following general structure: <CHEM> wherein  (a) X is a saturated or unsaturated, 5-, 6-, or 7-membered heterocycle or carbocycle; (b) R is selected from the group consisting of covalent bond, nil, heteroatom, carbonyl, heterocyclic ring, carbocyclic ring, alkyl, alkenyl, alkoxy, alkylamino, arylalkyl, aryloxy, acyl, acyloxy, and acylamino; (c) Y is a substituted or unsubstituted, saturated or unsaturated, 5-, 6-, or 7-membered heterocyclic ring or carbocyclic ring, or is nil;  and wherein when R is nil, X and Y are fused ring systems; and when R is a covalent bond, X and Y are ring systems linked through a covalent bond; and when Y is nil, R is a covalent bond, and X is bound to L through R;  (d) R1, R2, and R3 are independently selected from the group consisting of nil, Cl, F, Br, NH2, CF3, OH, SO3H, CH3SO2NH, COOH, alkoxy, alkyl, alkoxycarbonyl, hydroxyalkyl, carboxyalkyl, aminoalkyl, acylamino and acyloxy; (e) L is selected from the group consisting of alkylamino, alkenylamino, alkylimino, alkenylimino, and acylamino; wherein the nitrogen atom thereof is bound to the nitrogen atom at the 1-position of 4-oxocyclic urea moiety; (f) R4 is selected from the group consisting of alkyl, alkenyl, alkynyl, alkylacyl, and heteroalkyl; (g) A is a substituted or unsubstituted, saturated or unsaturated, straight-chain or branched, C1-C8 heteroalkyl; or a substituted or unsubstituted, saturated or unsaturated heterocycle having 5-, 6-, or 7-members; and A has one nitrogen atom, which is adjacent to R4; and (h) R5 is a substituted or unsubstituted C1 or C2 alkyl.
Patent PT-101036-A (PT)
Title: Process for the formation of polyurethane products containing cork-bark granules, especially for manufacturing footwear soles and equipment for implementing this process
Inventor: LOSIO GIANFRANCO
IPC: C08G71/04
Filed: 1992-11-05
Abstract: The formation of a polyurethane compound containing cork- bark or similar granules. The basic ingredients, which consist of isocyanates and polyols, are supplied to the inside of a mixing vessel (beaker) 14, which has a rotary shaft 16 with radial arms 18. Simultaneously, the cork- bark granules are introduced into the bottom part of the said mixer, via a conduit 32, inside which a conveyor screw 34 rotates, and they are mixed with the compound in the reaction stage. The equipment used for application of the process and which consists of the mixer and of the screw conveyor mentioned above, with the corresponding screw, is advantageously applicable also to known machines constructed for the production of products obtained only with polyurethane. <IMAGE>
Patent PT-101718-A (PT)
Title: Improved tank/system for fluids
Inventor: MAGALLON ISMAEL PEREZ
IPC: B32B1/02
Filed: 1995-06-02
Abstract: Improved tank/system D for fluids which, being a metallic structure 1, has over its entire outer surface a non- metallic protective coating 3 and comprises at least one and preferably a number of cathodic protection anodes 21 joined securely to the metallic structure 1 of the tank D. Preferably, each cathodic protection anode 21 is a zinc/lead body with ferric rods 22 via which it is securely joined by means of welding to the metallic structure 1 of the tank D and the non-metallic protective coating is a chlorine/rubber paint. <IMAGE>
Patent PT-101917-A (PT)
Title: Universal wheelchair for the disabled
Inventor: MOLEIRINHO JESUVINO
IPC: A61G5/00
Filed: 1996-09-23
Abstract: A wheelchair which comprises an articulated back 1 consisting of two parts with adjustable tilt via the tie- rod 3. According to the invention, the seat 4, consisting of two parts, rolls forwards and is supported on the foot column 7, providing the space 6 for penetration into the area of the bed. The pedals for the feet 13 are articulated and move backwards and forwards. The two manual levers 9 are the extension of the columns which support the pedals. It has an articulated central structure 14 for opening up or folding the chair. The invention is intended for people with paralyzed lower limbs and for the elderly, especially those effected by thromboses. <IMAGE>
Patent PT-105581-A (PT)
Title: Sistema centralizado de apoio à exploração
Inventor: ALMEIDA ANTONIO JULIO ALVES DE
IPC: G06Q10/08
Filed: 2011-03-22
Abstract: O SISTEMA CENTRALIZADO DE APOIO À EXPLORAÇÃO (SCAE) OBJETO DO INVENTO, É UM SISTEMA DE GESTÃO E DE TOMADA DE DECISÃO OPERACIONAL EM TEMPO REAL, QUE COBRE TODA A ATIVIDADE DA EMPRESA, NUMA ÓTICA DINÂMICA E TRANSVERSALMENTE ABRANGENTE. INTEGRA SISTEMAS OPERACIONAIS EXISTENTES, ACRESCENTANDO NOVAS POTENCIALIDADES E INOVA ABRINDO NOVOS CAMINHOS PARA ANÁLISE E TRATAMENTO DA INFORMAÇÃO DE GESTÃO. O SCAE CONSISTE PRINCIPALMENTE EM: A)UM SISTEMA DE INFORMAÇÃO DE GESTÃO, B)UM SISTEMA DE GESTÃO E DE TOMADA DE DECISÃO OPERACIONAL ALINHADO COM OBJETIVOS ESTRATÉGICOS E OPERACIONAIS PREVIAMENTE DEFINIDOS E C)UMA BASE DE DADOS, FUNDAMENTADA NA INFORMAÇÃO POR SI RECOLHIDA E DESTINADA AO PLANEAMENTO DA ATIVIDADE DA EMPRESA. ESTE SISTEMA REVOLUCIONA A ORGANIZAÇÃO DA EMPRESA E PROCESSOS OPERACIONAIS DE GESTÃO E DE TOMADA DE DECISÃO PERMITINDO NOVOS MODELOS DE AFETAÇÃO DE MEIOS E DE RECURSOS HUMANOS, COM FORTE IMPACTO POSITIVO NA EFICIÊNCIA GLOBAL DA EMPRESA. O SCAE ESTÁ CONCENTRADO NUMA SALA DE CONTROLO, DA QUAL SE GERE TODA A ATIVIDADE OPERACIONAL DA EMPRESA.
Patent PT-115035-A (PT)
Title: Condensador termoiónico carregável por efeito soret utilizando um gradiente de temperatura
Inventor: ANDRÉ MIGUEL TRINDADE PEREIRA
IPC: H02N3/00
Filed: 2018-09-24
Abstract: CONDENSADOR TERMOIÓNICO CARREGÁVEL POR UM GRADIENTE DE TEMPERATURA, COMPREENDENDO ELÉTRODOS DE CARBONO NANOESTRUTURADO E UM ELETRÓLITO SÓLIDO-GEL POLIMÉRICO COMPREENDENDO CATIÕES E ANIÕES TERMODIFUNDÍVEIS SOB UM GRADIENTE DE TEMPERATURA ENTRE OS REFERIDOS ELÉTRODOS POR EFEITO SORET. O CONDENSADOR PODE SER PLANAR EM QUE OS ELÉTRODOS SÃO DISPOSTOS AO LONGO DE DUAS REGIÕES SEPARADAS DE UM SUBSTRATO PLANAR QUE ESTÃO SEPARADAS POR UMA REGIÃO INTERMÉDIA DO REFERIDO SUBSTRATO, ESTANDO O ELETRÓLITO COLOCADO SOBRE OS REFERIDOS ELÉTRODOS E A REFERIDA REGIÃO INTERMÉDIA. O CONDENSADOR PODE SER EM CAMADAS, SENDO CADA ELÉTRODO UMA CAMADA REVESTIDA COM CARBONO NANOESTRUTURADO, COMPREENDENDO UMA CAMADA INTERMÉDIA DE ELETRÓLITO ENTRE AS CAMADAS DE ELÉTRODO, EM QUE AS REFERIDAS CAMADAS FORMAM UMA PILHA, EM PARTICULAR ESTANDO AS REFERIDAS CAMADAS COMPREENDIDAS NUMA CAMADA TÊXTIL OU SENDO CAMADAS TÊXTEIS.
Patent PT-115292-A (PT)
Title: Processo de produção de vinhos sem adição de anidrido sulfuroso por utilização de filmes com base em quitosana
Inventor: MANUEL ANTÓNIO COIMBRA RODRIGUES DA SILVA
IPC: C12G1/00
Filed: 2019-02-07
Abstract: A PRESENTE INVENÇÃO REFERE-SE A UM PROCESSO DE PRODUÇÃO DE VINHO UTILIZANDO O PROCESSO DE VINIFICAÇÃO TRADICIONAL COM A EXCEPÇÃO DE, APÓS A FERMENTAÇÃO, O VINHO SER COLOCADO EM CONTACTO COM UM FILME À BASE DE QUITOSANA E SEM ADIÇÃO DE ANIDRIDO SULFUROSO AO VINHO. A PRESENTE INVENÇÃO REFERE-SE AINDA A UM PROCESSO DE PREPARAÇÃO DO FILME À BASE DE QUITOSANA POR MODIFICAÇÃO DA QUITOSANA COM COMPOSTOS NATURAIS QUE PERMITEM PRODUZIR FILMES DE QUITOSANA ESTÁVEIS EM MEIO ÁCIDO, COM ELEVADA ACTIVIDADE ANTIOXIDANTE E MANTENDO A ACTIVIDADE ANTIMICROBIANA. NUMA FORMA DE REALIZAÇÃO, OS FILMES SÃO PREPARADOS POR LIGAÇÃO COVALENTE À QUITOSANA DE MOLÉCULAS QUE PERMITEM AUMENTAR A SUA INSOLUBILIDADE EM MEIO ÁCIDO, COMO POR EXEMPLO A GENIPINA, E DE MOLÉCULAS COM ELEVADA ACTIVIDADE ANTIOXIDANTE, COMO POR EXEMPLO O ÁCIDO CAFEICO OU EXTRACTOS DE UVA OU VINHO RICOS EM COMPOSTOS COM ACTIVIDADE ANTIOXIDANTE.