baber/WOPTO huggingface dataset:
Patent EP-0478721-B1 (EP)
Inventor: VON SPRECHER ANDREAS
IPC: C07C62/38
Filed: 1991-03-19
Granted: 1995-09-06
Abstract: Le nouvel acide (S)-4-(2-bromobenzoyle)-5-hydroxy-benzocyclobutene-1-carboxylique, c'est-à-dire le composé de la formule (I), sous forme libre ou de sel, peut être utilisé comme agent actif dans des préparations pharmaceutiques et peut être produit selon un nouveau procédé qui se caractérise par le fait que l'on fait réagir de l'acide racémique 4-(2-bromobenzoyle)-5-hydroxy-benzocyclobutene-1-carboxylique dans un solvant alcoolique pendant environ 6 à 48 heures à haute température avec au moins la quantité équimoléculaire de quinine; le produit cristallin immédiat de la réaction, qui est le sel de quinine de l'acide (S)-4-(2-bromobenzoyle)-5-hydroxy-benzocyclobutene-1-carboxylique est séparé du mélange de réaction et l'acide (S)-4-(2-bromobenzoyle)-5-hydroxy-benzocyclobutene-1-carboxylique est libéré de ce sel par un traitement acide habituel et cet acide libre est éventuellement réduit en un sel.
Patent EP-0544673-B1 (EP)
Inventor: JONES CHARLES E
IPC: F25D3/08
Filed: 1990-08-30
Granted: 1997-07-16
Abstract: PCT No. PCT/US90/04931 Sec. 371 Date Nov. 18, 1991 Sec. 102(e) Date Nov. 18, 1991 PCT Filed Aug. 30, 1990 PCT Pub. No. WO92/04586 PCT Pub. Date Mar. 19, 1992.A soft-sided cooler is disclosed having a pivotably fastenable lid and a coolant container dimensioned to fit snugly within the underside region of the lid as defined by a plurality of generally opposing, inwardly facing sidewalls that extend downward towards the cooler body for fastening thereto when the lid is closed. The container is retained within the underside of the lid by VELCRO fastening surfaces on the container which mate with VELCRO fastening surfaces on at least a generally opposing pair of the sidewalls.
Patent EP-0531386-B1 (EP)
Inventor: BICKEL WAYNE J
IPC: F42B6/06
Filed: 1991-05-14
Granted: 1994-10-19
Abstract: Adaptateur d'encoche (22, 94) permettant le montage d'une encoche sur le fût d'une flèche. L'adaptateur d'encoche (22, 94) comporte des trous (32, 104 et 36, 106) à chaque extrémité permettant d'engager un fût (16, 90) et une encoche (20, 26), respectivement. Dans une de ces formes, l'invention s'adapte à l'intérieur du fût de la flèche (16) et permet de monter une encoche classique (20) sur sa surface de montage conique (58), où une encoche A.C.E. (26) s'engageant dans un passage cylindrique (36) de l'adaptateur d'encoche (22). Dans une variante, l'invention reçoit le fût (90) d'une flèche au niveau d'une extrémité (98) et elle reçoit une encoche A.C.E. (26) au niveau de l'autre extrémité (100), tout en ayant une surface extérieure cylindrique (114) optimalisant le vol de la flèche (90). Ledit adaptateur d'encoche (22, 94) se compose de préférence d'aluminium qui lui confère une rigidité structurelle et un poids léger.
Patent EP-0531407-B1 (EP)
Inventor: CAMPBELL ROBERT K
IPC: C07K19/00
Filed: 1991-05-07
Granted: 2000-02-09
Abstract: Polypeptides hétérodimères alpha, bêta modifiés de gonadotropine chorionique (GC) comprenant un polypeptide de sous-unité alpha d'hormone de glycoprotéine et une sous-unité bêta de polypeptide n'existant pas naturellement. Les modifications dans les polypeptide de sous-unité bêta sont la suppression, l'adjonction, ou la substitution d'un ou plusieurs restes d'acides aminés. Les polypeptides hétérodimères modifiés selon la présente invention ont des propriétés différentes comparées à celles de la CGh native. Certains polypeptides hétérodimères alpha, bêta se lient à des récepteurs de LH et de FSH et stimulent la stéroidogenèse des cellules ovariennes et testiculaires. D'autres polypeptides hétérodimères alpha, bêta se lient à des récepteurs de LH mais sont moins efficaces que la GCh pour stimuler la stéroidogenèse des cellules ovariennes et testiculaires.
Patent EP-0548243-B1 (EP)
Inventor: BJOERKMAN MATS
IPC: F17D5/00
Filed: 1991-09-04
Granted: 1994-11-30
Abstract: PCT No. PCT/SE91/00579 Sec. 371 Date Mar. 8, 1993 Sec. 102(e) Date Mar. 8, 1993 PCT Filed Sep. 4, 1991 PCT Pub. No. WO92/05385 PCT Pub. Date Apr. 2, 1992.The method and apparatus relates to a procedure and an arrangement for minimizing the risk of the undesired escape of water from pipe systems and units connected thereto in premises and similar surroundings by the use of a control or valve arrangement arranged at the point of connection of the pipe system to the external supply pipe and capable of regulation by means of an adjuster device. A link is provided between the valve arrangement and the device for detecting the presence or movement of individuals inside the premises, and the operation is such that, in the event of the detection of presence or movement, the valve is kept open so as to permit water to enter the pipe system or network, whereas the valve is kept closed in the absence of such detection.
Patent EP-0496373-B1 (EP)
Inventor: FISCHER ANDREAS
IPC: C07C237/12
Filed: 1992-01-22
Granted: 1998-05-06
Abstract: Protected and unprotected di- or oligopeptides are synthesized by reacting an N-terminally protected (alpha)-amino acid alkyl ester or peptide alkyl ester of the formula X-E-R1 with an amino acid or a di- or oligopeptide or a derivative thereof of the formula H2N-Q-R2 in aqueous solution in the presence of a hydrolase, and, removing protective groups from the reaction product separated from the reaction mixture, where E is the residue of an (alpha)-amino acid or of a di- or oligopeptide, R1 is lower alkyl and X is a group which carries a charge or is polar at the pH values used for the reaction and which increases the solubility by a factor >5 compared with compounds wherein X=H, Q is the residue of an amino acid or of a di- or oligopeptide, and R2 is an optionally esterified or amidated acid group. In a preferred embodiment, the peptide or ((alpha)-)amino acid ester concentration is greater than 50 mM, wherein in a particularly preferred embodiment, the concentration ranges from 100 to 1000 mM with approximately comparable nucleophile and electrophile concentrations. The preferred substrate/enzyme ratios are >105 M/M or >103 M/M when papain is employed. Phthalyl, maleyl or citraconyl radicals and their derivatives or N-betainyl compounds are envisaged for use radicals (X) in the electrophilic component.
Patent EP-0499895-B1 (EP)
Inventor: KOEDER PAUL
IPC: B27D1/08
Filed: 1992-02-06
Granted: 1995-05-10
Abstract: A device for shaping an optionally pressing curved components, such as curved beams of glued laminated girders, is provided which, in a modular type of construction, comprises at least two clamping devices on a base, which are movable. Each clamping device has, as a foundation, a slide that is movable along guides which, for example, are movable with rollers along a pair of rails as guides. In the central part of the slide, a rotary table is rotatable around an axis perpendicular to the slide, on which at least two adjustable clamping elements, symmetrical to the axis of rotation, are provided. To adjust these clamping elements, which can be formed by tighteners, an adjusting device is placed centered on the slide. With this adjusting device, the tighteners are moved toward, and away from, each other symmetrically relative to the axis of rotation in their opposite arrangement. A manual control or a computer-aided control can be used to control the device.
Patent EP-0528109-B1 (EP)
Inventor: KREYENBORG JAN-UDO
IPC: B29C48/03
Filed: 1992-05-02
Granted: 1994-10-26
Abstract: It is proposed that, in a device in which two sieve support bolts (3) are arranged in a housing (1), a procedure is followed in which each sieve support bolt (3) has an auxiliary channel (9). This auxiliary channel (9) can, by adjustment of the sieve support, be positioned in front of the point of entry of the inlet channel or of the sub-channels (6, 7) which are connected to the inlet channel (5), so that the first plastic material is now fed from the inlet channel (5) through the sub-channels (6, 7) to the auxiliary channel (9). <IMAGE>
Patent EP-0498722-B1 (EP)
Inventor: CLEMENCE FRANCOIS
IPC: C07D217/12
Filed: 1992-02-05
Granted: 1997-07-30
Abstract: The subject of the invention is the products of formula (IB): <IMAGE>  in which: R2B and R3B, which are identical or different, represent hydrogen; halogen; hydroxyl; mercapto; cyano; nitro; sulpho; formyl; benzoyl; acyl; carboxy in the free, salt or ester form; cycloalkyl; acyloxy; alkyl; alkenyl; alkynyl; alkyloxy; alkylthio; aryl; arylalkyl; arylalkenyl; aryloxy or arylthio;  d) a radical <IMAGE> where R6B, R7B, R8B and R9B represent hydrogen or optionally substituted alkyl, alkenyl, aryl or arylalkyl, or -(CH2)m1-S(O)m2-X-R14, where m1 represents 0 to 4, m2 represents 0 to 2, X-R14 represents -NH2 or X represents -NH , NH-CO-, -NH-CO-NH- or a single bond and R14 represents optionally substituted alkyl, alkenyl or aryl.
Patent EP-0527117-B1 (EP)
Inventor: VAN KEULEN BEREND JAN
IPC: A61K31/541
Filed: 1992-07-09
Granted: 1997-10-29
Abstract: New cyclopropylamino-1,3,5-triazines and their salts, processes for their preparation and therapeutic compositions. These compounds correspond to the formula <IMAGE>  in which     R1 = alkyl, cycloalkyl or alkylcycloalkyl, R2 = bis(2-hydroxyethyl)amino, 3-hydroxy-1-azetidinyl, 3-methoxy-1-azetidinyl, 3-oxo-1-azetidinyl, morpholino, 4-hydroxypiperidino, thiomorpholino, thiomorpholino S-oxide, thiomorpholino S,S-dioxide, 3-thiazolidinyl, 3-thiazolidinyl S-oxide, 3-thiazolidinyl S,S-dioxide or 8-oxa-3-azabicyclo[3.2.1]oct-3-yl.   These compounds are useful in the treatment of disorders associated with Alzheimer's disease, Alzheimer-type senile dementias and all evolutive cognitive pathologies and in the treatment of depression, anxiety, mood disorders, inflammatory phenomena and asthma.
Patent EP-0496725-B1 (EP)
Inventor: LINNAU YENDRA DR
IPC: C12N9/64
Filed: 1992-01-23
Granted: 1996-12-11
Abstract: Factor IX is selectively adsorbed by means of hydrophobic chromatography from an aqueous mixture containing at least one plasma zymogen or a vitamin-K dependent protein in addition to factor IX. By this method, the efficient enrichment of factor IX for the production of pharmaceutical preparations has become possible.
Patent EP-0561857-B1 (EP)
Title: Filtre epurateur centrifuge
Inventor: REDL SIMON
IPC: B01D29/41
Filed: 1991-12-09
Granted: 1995-09-13
Abstract: Un filtre horizontal comprend un récipient de filtrage qui contient un agencement d'éléments de filtrage superposés et mutuellement espacés, et un dispositif distributeur qui fournit la substance à filtrer à l'agencement de filtrage dans une direction principale d'écoulement de bas en haut. Des conduits d'amenée de la substance à filtrer aux éléments individuels de filtrage partent du dispositif distributeur. Afin d'obtenir un filtre horizontal de plus grande capacité, le dispositif distributeur comprend des conduits distributeurs qui s'étendent entre la paroi du récipient de filtrage et l'agencement de filtrage, ainsi que des conduits d'amenée qui partent des conduits distributeurs et qui sont répartis autour de la circonférence des éléments individuels de filtrage. Les conduits d'amenée sont pourvus chacun d'une chambre de stabilisation de l'écoulement qui comprend au moins une ouverture de communication avec un conduit distributeur et au moins une ouverture de sortie de la substance à filtrer située au-dessus de l'élément de filtrage correspondant.
Patent EP-0516785-B1 (EP)
Inventor: ADAIR JOHN ROBERT
IPC: C12N15/11
Filed: 1991-12-20
Granted: 1996-02-21
Abstract: Recombinant, in particular humanised, e.g. humanised chimeric and CDR-grafted humanised, antibody molecules having specificity for human TNF alpha , are provided for use in diagnosis and therapy. In particular the antibody molecules have antigen binding sites derived from murine monoclonal antibodies CB0006, CB010, hTNF3 or 101.4. Preferred CDR-grafted humanised anti-hTNF alpha  antibodies comprise variable region domains comprising human acceptor framework and donor antigen binding regions and wherein the frameworks comprise donor residues at specific positions. The antibody molecules may be used for therapeutic treatment of human patients suffering from or at risk of disorders associated with undesirably high levels of TNF, in particular for treatment of immunoregulatory and inflammatory disorders or of septic, endotoxic or cardiovascular shock. <IMAGE>
Patent EP-0580779-B1 (EP)
Inventor: LYON LELAND H
IPC: F16D41/20
Filed: 1992-04-16
Granted: 1995-03-01
Abstract: Un ensemble d'accouplement (16) transmet le mouvement rotatif d'un appareil à percussion (10) à un acier à fleurets. L'ensemble d'accouplement comprend un premier moyeu (18) sur lequel est formé une première surface cylindrique (24). Sur un second moyeu (20), couplé rotatif à l'acier à fleuret, est formée une seconde surface cylindrique (26). Ladite seconde surface cylindrique (26) est coaxiale avec ladite première surface cylindrique (24). Un ressort enroulé (17) vient au contact d'une partie à la fois de la première surface cylindrique (24) et de la seconde surface cylindrique (26), de manière que le mouvement rotatif relatif entre le premier moyeu (18) et le second moyeu (20) est possible dans un premier sens et empêché dans un second sens. L'accouplement (16) par ressort enroulé transmet le mouvement produit par l'ensemble tige du marteau perforateur ainsi qu'un agencement de tiges de plongeur.
Patent EP-0541773-B1 (EP)
Inventor: HILL JOHN LESLIE III
IPC: E21B47/022
Filed: 1992-05-28
Granted: 1997-01-22
Abstract: A method and apparatus are disclosed for determining the position of a centerline of a passageway by using a measuring instrument which passes through the passageway taking periodic and successive axial strain measurements which are in turn used to form an interconnected series of circular arc segments representing the centerline.
Patent EP-0642649-B1 (EP)
Inventor: BAUER HEINZ
IPC: F25J3/02
Filed: 1992-08-13
Granted: 1996-01-10
Abstract: Il est décrit un procédé de séparation d'hydrocarbures à température d'ébullition supérieure dans un mélange gazeux contenant ces hydrocarbures et des constituants à température d'ébullition inférieure, par décomposition par distillation fractionnée. Le mélange gazeux (6) est condensé partiellement (7) et amené à une colonne de séparation (9). Une fraction (27) riche en hydrocarbures est soutirée du fond de la colonne (9), cependant qu'une fraction (10) riche en constituants à température d'ébullition inférieure est soutirée en tête de colonne. La fraction de tête (10) est condensée partiellement (11). Le condensat ainsi formé est recyclé dans la colonne de séparation (9). La condensation partielle du mélange gazeux, tout comme la condensation partielle de la fraction de tête sont produites par échange thermique indirect (7, 11) avec un agent réfrigérant qui est formé de plusieurs constituants et qui est envoyé dans un circuit extérieur (18).
Patent EP-0554745-B1 (EP)
Inventor: KUBITZA WERNER DIPL-ING
IPC: C09D175/02
Filed: 1993-01-25
Granted: 1997-03-05
Abstract: A process for the production of coatings on water-resistant substrates using an aqueous coating composition which essentially comprises a) a water-compatible organic polyisocyanate as binder, b) water and optionally c) conventional auxiliaries and additives.
Patent EP-0561196-B1 (EP)
Inventor: KLEINMICHEL KLAUS
IPC: B05B9/03
Filed: 1993-02-27
Granted: 1997-04-23
Abstract: The spraying apparatus includes a medium-outlet nozzle with conical outlet opening and also an annular air nozzle and a plurality of horn-shaped air nozzles arranged opposite each other and directed obliquely inwards towards the emerging jet of medium. The spraying apparatus operates in a high-pressure process at about 70 to 300 bar if an application jet of large surface area is to be discharged, the compressed air delivery being switched off in this operating state. If the jet of medium is to be constricted, the hydraulic volumetric feeder intended for supplying the medium reduces the medium pressure to about 10 to 70 bar, the compressed air supply being switched on at the same time. The compressed air delivery from the annular air nozzle and the horn-shaped air nozzles is set by means of air control valves in such a way that the jet of medium takes on the desired geometry. With a control unit, the parameters can be externally entered and monitored. <IMAGE>
Patent EP-0595081-B1 (EP)
Inventor: MOELTGEN PAUL DR
IPC: C04B35/10
Filed: 1993-10-06
Granted: 1997-07-16
Abstract: The present invention relates to an abrasive grain based on  alpha -Al2O3 and ZrO2 containing titanium compounds in the form of sub-oxides, carbides and/or oxycarbides, a process for the production thereof, and use thereof.
Patent EP-0584873-B1 (EP)
Inventor: BUCKS MARCEL JOHANNES MARIA
IPC: H02M1/00
Filed: 1993-08-18
Granted: 1997-12-10
Abstract: The invention relates to a circuit arrangement for operating an incandescent lamp with a current of periodically changing polarity, which circuit arrangement is provided with a static converter (I) with power switching means (T1, T2) and capacitive means (C1, C2) for generating the current of periodically changing polarity. The circuit arrangement also comprises starting means (II) for starting the static converter. According to the invention, the circuit arrangement is provided with delay means (III) which delay the start after connection of a supply source. <IMAGE>
Patent EP-0580503-B1 (EP)
Inventor: PAYARD MARC
IPC: C07D521/00
Filed: 1993-07-21
Granted: 1995-06-14
Abstract: The invention relates to compounds of general formula (I): <IMAGE> with R1, R2, R3, R4, R5, R6 and Z defined in the description, to their optical isomers and to their addition salts with a pharmaceutically acceptable acid or base. Medicaments.
Patent EP-0597738-B1 (EP)
Inventor: CHOPIN THIERRY
IPC: C01F7/02
Filed: 1993-10-05
Granted: 1997-07-23
Abstract: Alumina stabilised with lanthanum, retaining a high specific surface at high temperature, especially after calcination at 1200@C for 4 hours. Process for the preparation of this stabilised alumina from an alumina powder originating from the rapid dehydration of an aluminium hydroxide or oxyhydroxide, in which the said powder is rehydrated in the presence of a lanthanum compound and then subjected to a heat treatment. Use of this stabilised alumina as catalyst support.
Patent EP-0603110-B1 (EP)
Inventor: THURSTON MARLIN O
IPC: A61N5/10
Filed: 1993-12-09
Granted: 1999-01-20
Abstract: A laparoscopic instrument is provided having a hand-grippable base (12) to which an elongate accessing tube (14) is connected which extends to a tip (16). Extending inwardly from the tip (16) is a detection support region (18) within which is formed a radiation transmissive window (22). Immediately spaced from and behind the window (22) there is positioned a detecting crystal (60) such as cadmium telluride which is retained in a crystal mount structure (26) having an architecture designed for minimizing noise generation occasioned from microphonic (piezoelectric) phenomena and the like. <IMAGE>   <IMAGE>
Patent EP-0573665-B1 (EP)
Inventor: YONEMITSU JUN
IPC: H04N21/434
Filed: 1992-12-28
Granted: 1998-09-30
Abstract: A highly efficient coding/decoding by subjecting image signals to orthogonal transformation, by which all data of interlace images, inclusive of scarce and rich types of images in motions and even a mixed type thereof, can be coded efficiently. A circuit (19) senses motion vectors in every macro-block between an odd-numbered field and an even-numbered field. A circuit (21) determines the coding mode (coding of every field or coding of every frame), according to the median of the motion vectors. A control circuit (16) controls gates (15, 17) and switches (6, 9, 10, 15) corresponding to the determined coding mode, and it generates a predictive image of every field or frame from buffer memories (7, 8). Circuits from a difference circuit (22) to a VLC circuit (25) calculate the difference data between an image to be coded and the predictive picture thereof, subject the difference data to discrete cosine transformation, and thereafter perform variable-length coding. Also, the VLC-circuit (25) sets the coding mode as a flag in the header of the predetermined hierarchy of a bit stream. <IMAGE>
Patent EP-0631585-B1 (EP)
Inventor: JOERGENSEN PER LINAA
IPC: C12N9/00
Filed: 1992-12-11
Granted: 1998-09-30
Abstract: A process for the microbial production of a protein susceptible to inactivation in a fluid production medium by continuously and reversibly protecting said protein against said inactivation during the production stage, separating the protein from the production medium, deprotecting the protein, and recovering the protein product. The process is especially useful for obtaining substantially increased yields of the protein in question by continuously precipitating said protein.
Patent EP-0630288-B1 (EP)
Inventor: BONSE DIRK
IPC: B01J23/89
Filed: 1993-03-08
Granted: 1996-01-17
Abstract: PCT No. PCT/EP93/00525 Sec. 371 Date Sep. 13, 1994 Sec. 102(e) Date Sep. 13, 1994 PCT Filed Mar. 8, 1993 PCT Pub. No. WO93/17786 PCT Pub. Date Sep. 16, 1993.The description relates to a particularly abrasion-resistant catalyst carrier of special activated aluminum oxide. The aluminum oxide consists of either the "gamma" or the "kappa" modification and has no "delta" modification, or it consists of the "kappa" and "theta" modifications and has no "alpha" modification. Carrier catalysts which contain catalytically active metals and/or metal compounds on the abrasion-resistant carrier are especially suitable for use in fluidized bed processes.
Patent EP-0636293-B1 (EP)
Inventor: FOSTER PETER J
IPC: H04Q3/42
Filed: 1993-04-14
Granted: 2003-06-25
Abstract: Un centre de service téléphonique pour communications interurbaines est accessible par des abonnés au service. Les abonnés ont leur propre ensemble d'identificateurs associés de manière unique à plusieurs postes téléphoniques appelés auxquels ils désirent avoir accès. Le centre comprend un système de commande vocale (10) ayant une mémoire (16) pour stocker des représentations des identificateurs en des emplacements mémoire identifiés uniquement avec l'abonné. Le système de commande (10) comprend également un circuit d'annonce et un processeur (30). Le processeur (30) est sensible à la réception d'un appel entrant provenant d'un abonné afin de commander le circuit d'annonce qui demande à l'abonné de prononcer un identificateur associé à l'un des plusieurs postes appelés. Un dispositif de reconnaissance de la parole (48) est sensible à la réception de l'identificateur afin de déterminer si ce dernier est valide. Si l'identificateur est reconnu comme appartenant à l'abonné, le processeur commande un dispositif de numérotation directe à l'extérieur (24) afin de composer le numéro de téléphone du poste appelé associé à l'identificateur.
Patent EP-0650552-B1 (EP)
Title: Metallischer wabenkörper aus verschlungenen blechlagen und verfahren zu seiner herstellung
Inventor: MAUS WOLFGANG
IPC: B01D53/86
Filed: 1993-06-23
Granted: 1996-04-17
Abstract: Metallischer Wabenkörper mit umeinandergeschlungenen, zumindest teilweise strukturierten Blechlagen (3, 4), die gekrümmt, insbesondere etwa evolventenförmig, verlaufen, wobei der Körper in einem äußeren Ringbereich (6) und in einem inneren Ringbereich (5) je mindestens drei Umkehrlinien (2a, 2b, 2c, ... bzw. 7a, 7b, 7c, ...) aufweist, um welche die Blechlagen (3, 4) mit sich von Außen nach innen jeweils ändernder Krümmungsrichtung verschlungen sind. Ein solcher Körper kann aus einem Hohlwickel durch sternförmiges Verformen und anschließendes Verschlingen der äußeren Teile um die inneren Teile hergestellt werden und ist daher fertigungstechnisch sehr vorteilhaft. Auch kann ein langer elektrischer Leiter als Meßfühler oder Heizleiter integriert werden. Die mechanischen Vorteile eines Wabenkörpers mit einer Vielzahl gebogener von innen nach außen verlaufender Blechlagen bleiben erhalten. Ein solcher Wabenkörper ist daher bevorzugt als Abgaskatalysator-Trägerkörper in Kraftfahrzeugen einsetzbar.