baber/WOPTO huggingface dataset:
Patent CA-2919690-A1 (CA)
Inventor: KARMALI RASHIDA A
IPC: C12Q1/68
Filed: 2014-07-30
Abstract: This invention provides methods, pharmacodynamics biomarker signatures for multiple signaling pathways in a cell, sample such as anagen hair, in response to carboxyamidotriazole orotate (CTO) from a subject CTO has demonstrated response in several cancers having different genomic mutations m clinical studies. This invention provides a diagnostic and prognostic assay for monitoring response to CTO ranging from - l00fold to +25 fold differential expression in several transcriptional signatures associated with tumor inhibition including EGFR, MEK, HDAC, RAS, GFS, WNT, HSP90 or non-voltage dependent calcium signaling, while inducing tumor suppressors signatures such as P53 or EGR1 in the anagen hair assay.
Patent CA-2921239-A1 (CA)
Inventor: DICKIE ROBERT
IPC: A61J7/04
Filed: 2014-08-08
Abstract: A medication reminder and compliance system including a pill box, a pill box and electronic device; or a pill box, electronic device and remote server. The pill box includes several detachable dosettes, each divided into several chambers having a door. A two-color LED is disposed beneath each chamber and is activated when a specific reminder time is reached. The LED initially illuminates the associated chamber with a green light but changes to a flashing red light if the door is not opened within a preset time. A switch engaged with the door deactivates the LED when the door is opened. The electronic device communicates with the pill box and alerts the patient when it is time to take medication. A remote server which communicates with both the pill box and electronic device can be programmed to control the reminder schedule and monitor the patient's compliance with a prescribed medication regimen.
Patent CA-2922636-A1 (CA)
Title: Seed firmer life extender
Inventor: JEFFREY PETER J
IPC: A01C5/00
Filed: 2013-08-27
Abstract: The present invention involves a seed firmer with a pusher attachment that extends the life of the seed firmer. The seed firmer construction provides a replaceable tip or end for extending the life of the firmer, generally having two components that degrade with use, the flexible arm and the embedding pusher. The flexible arm generally lasts much longer than the embedding pusher portion because the pusher wears against the ground and eventually wears away. Embodiments of the invention include an embedding pusher portion that has a stop and a guide for accepting a replaceable extender. Other embodiments include an embedding pusher portion that engages the rest of the firmer arm. Thus, the portion of the firmer that wears down may be easily replaced which extends the life of the firmer, multiple times over the useful life of the flexible ann.
Patent CA-2924404-A1 (CA)
Inventor: HOSKINS TERRY
IPC: E21B33/138
Filed: 2014-09-12
Abstract: The present invention relates generally to drilling and well servicing operations, particularly to additives comprising polystyrene to control lost circulation; drilling fluids comprising the additives; and methods of using same.
Patent CA-2924600-A1 (CA)
Title: Biomarqueurs d'autoanticorps du cancer des ovaires
Inventor: HOFFMANN PETER
IPC: G01N33/574
Filed: 2014-09-18
Abstract: La présente invention concerne l'identification de marqueurs biologiques du cancer des ovaires. Spécifiquement, des auto-anticorps associés au cancer à ANXA1, ARP3, SAHH, SERPH, ARAP1, OTUB1, ATP1A1, UBA1 et CFAH ont été identifiés chez des sujets présentant un cancer des ovaires de stade précoce. Ces auto-anticorps peuvent être utilisés pour une gamme d'objectifs, y compris des méthodes destinées à détecter un cancer des ovaires, des méthodes de criblage de cancer des ovaires de stade précoce et des méthodes d'évaluation de la réponse au traitement ainsi que de la progression et de la récidive de la maladie. Les auto-anticorps représentent également des marqueurs de pronostic de développement du cancer des ovaires.
Patent CA-2927423-A1 (CA)
Title: Anti-thrombotic material
Inventor: FUJITA MASAKI
IPC: A61L33/00
Filed: 2014-11-27
Abstract: The purpose of the present invention is to provide an anti-thrombotic material in which heparin or an anti-thrombotic compound other than a heparin derivative is fixed to a base material, elution of the compound exhibiting anti-thrombotic properties from the base material is avoided, and high anti-thrombotic properties are maintained over a long period. The present invention provides an anti-thrombotic material that includes: a covering material containing a polymer skeleton structure, a 4-(aminomethyl)benzene carboxy-imidamide or a benzene-amidine skeleton structure, and a methoxy benezene sulfonic acid amide skeleton structure; and a base material containing a surface that is covered by the covering material. The covering material is covalently bonded with the base material, and a peak abundance ratio of carbonyl-group-derived components on the surface, with respect to all the components of a C1s peak measured using X-ray electron spectroscopy, is equal to or greater than 1.0 atom number %.
Patent CA-2928523-A1 (CA)
Inventor: LI CHANGLE
IPC: B60J10/20
Filed: 2014-10-29
Abstract: A windshield and a sealing element are provided. The sealing element (100) includes a supporting part (131) secured to an edge of a glass substrate (110) and a sealing part (132) integrated with the supporting part (131), viewing from a cross-sectional perspective of the windshield, the sealing part (132) being substantially configured with a semicircle or semielliptical shape, wherein the supporting part (131) and the sealing part (132) define therebetween a space to allow the sealing part (132) to deform when being fixed into the opening. The windshield includes a glass substrate (110) and the sealing element (100). In the present disclosure, difficulty of fabricating a windshield may be decreased.
Patent CA-2930900-A1 (CA)
Inventor: ELLIS DAVID J
IPC: A61K31/485
Filed: 2004-10-01
Abstract: The present invention is direct to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivicaine, clonidine, hydromorphone, baclofen, fentanyil, buprenorphine, and sufentanil, or its pharmaceutically acceptable salts thereof, wherein the omega-conopeptide retains its potency and is physically and chemically compatible with the analgesic compound. A preferred route of administration is intrathecal administration, particularly continuous intrathecal infusion. The present invention is also directed to a pharmaceutical formulation comprising an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivicaine, clonidine, hydromorphone, baclofen, fentanyl, buprenorphine, and sufentanil.
Patent CA-2932055-A1 (CA)
Title: Vaccin a base de mers-cov
Inventor: WEINER DAVID B
IPC: A61P31/14
Filed: 2014-11-26
Abstract: L'invention concerne un vaccin comprenant un antigène du coronavirus du syndrome respiratoire du Moyen-Orient (MERS-CoV). L'antigène peut être un antigène consensus. L'antigène consensus peut être un antigène Spike consensus. L'invention concerne également une méthode de traitement d'un sujet en attente d'un tel traitement, par administration du vaccin au sujet.
Patent CA-2937629-A1 (CA)
Inventor: GUSTAFSON RYAN
IPC: E21B33/06
Filed: 2009-12-03
Abstract: Method and device to be used for resetting a pressure in a low pressure recipient (60) connected to a subsea pressure control device. The device includes the low pressure recipient (60) configured to have first (77) and second (76) chambers separated by a first piston (74); a reset recipient (70) configured to have third (86) and fourth (88) chambers separated by a piston assembly (80), and the piston assembly (80) includes a second piston (82) having first (84) and second (100) extension elements that extend along a direction of movement of the piston assembly (80). The third chamber (86) has an inlet (90) configured to allow the hydraulic liquid to enter the third chamber (86) and an outlet (108) configured to allow the hydraulic liquid to exit the third chamber (86), and the fourth chamber (88) has an inlet (92) configured to allow the hydraulic liquid to enter the fourth chamber (88) and an outlet configured to allow the hydraulic liquid to exit the fourth chamber (88).
Patent CA-2939660-A1 (CA)
Inventor: HUANG JINGJUN
IPC: A61K47/44
Filed: 2015-02-16
Abstract: The present disclosure provides a pharmaceutically acceptable, stable, and optically clear oil- in- water nanoemulsions (intensity-averaged diameter<100 nm) with an oil phase comprising >10% w/v of long chain triglyceride, total surfactant and cosurfactant concentration less than that of oil phase and without the use of alcohol as cosolvent in the aqueous phase. The nanoemulsions of this disclosure have extremely favorable particle size distribution, optical clarity, and product stability against Ostwald ripening with high levels of oil concentrations. Poorly water soluble, therapeutically active agents and others can be incorporated in the nanoemulsion systems to improve their solubility/stability in aqueous medium or to enhance their delivery for use in pharmaceutical, food, cosmetic, and other applications by oral, intravenous, subcutaneous, intra muscular, inhalation, nasal, topical, ocular, and transdermal routes.
Patent CA-2940117-A1 (CA)
Title: Float apparatus
Inventor: WORKMAN JEFFREY D
IPC: F16K31/18
Filed: 2015-02-20
Abstract: A float valve apparatus is provided for regulating the level of fluid within a tank. The apparatus may include a housing having one or more inlet ports and an outlet port that are each fluidly connected via a channel disposed within the housing. A float disposed within the housing may move relative to the housing between a first position and a second position when a fluid level in the tank reaches a preset level. A shaft may extend from the float into a chamber, and as the float moves from the first position to the second position, fluid may enter a chamber and bias the float further upward. In some examples, the shaft is further configured to increasingly obstruct the flow of fluid in the channel as the float moves from the first position to the second position.
Patent CA-2940709-A1 (CA)
Inventor: GARNER ELIJAH B
IPC: A01C7/16
Filed: 2016-08-30
Abstract: A seed boot assembly for a seeding machine includes a seed boot, a boot liner and a seed tube adapter. The seed boot has a seed passage extending from an inlet to an outlet. The boot liner extends within the seed passage between the inlet and the outlet. A seed tube adapter is coupled to the seed boot and/or the boot liner.
Patent CA-2940760-A1 (CA)
Inventor: PURI COLIN ANIL
IPC: G06F17/00
Filed: 2016-08-31
Abstract: According to examples, intelligent data munging may include ascertaining data that is to be transformed, and determining, based on an analysis of the ascertained data, a sample of the ascertained data. Intelligent data munging may further include enriching the sample of the ascertained data, determining features of the enriched sample of the ascertained data, and determining, based on the features, a transformation to be applied to the enriched sample of the ascertained data to transform the enriched sample of the ascertained data from a first format to a second format. Further, intelligent data munging may include validating the determined transformation, and generating, based on the validation of the determined transformation, a script that is to be applied to the ascertained data to transform the ascertained data from the first format to the second format.
Patent CA-2942363-A1 (CA)
Title: Suivi de capteur electro-optique militaire
Inventor: ROTVOLD OYVIND
IPC: F41G5/14
Filed: 2016-09-19
Abstract: Il est décrit une plate-forme darmes (i) comme un véhicule blindé de combat, un char, un véhicule de patrouille en mer ou un élément comparable, laquelle comprend une unité de capteurs électro-optiques (4) comprenant un ou plusieurs capteurs (5) comme un système de caméra à fort grossissement, un système de caméra à faible niveau lumineux, un capteur infrarouge, un appareil de mesure des distances au laser ou un élément comparable, connectés à la plate-forme darmes (i); un poste de tir télécommandé (2) couplé à la plate-forme darmes (i); et une arme (3) couplée au poste de tir télécommandé (2) pour viser une cible avec larme télécommandée en fonction des données reçues de lunité de capteurs (4). La plate-forme darmes se distingue par une caméra de poursuite électro-optique (7) connectée à lunité de capteurs (4); au moins trois cibles (8) disposées sur la plate-forme d'armes (1), le poste de tir télécommandé (2) ou larme (3), les positions relatives des cibles les unes par rapport aux autres étant connues et les cibles étant observables par la caméra (7); et des moyens permettant de calculer la relation entre la position de lunité de capteurs (4) et de larme (3) dans les six degrés de liberté (X, Y, Z, tangage, lacet et roulis).
Patent CA-2943378-A1 (CA)
Inventor: PANNELL RICHARD B
IPC: C08F210/16
Filed: 2015-03-10
Abstract: Continuity compositions are provided as are methods of their preparation. The compositions comprise at least one metal carboxylate salt which is modified with at least one molten fatty amine. These compositions find advantageous use in olefin polymerization processes.
Patent CA-2945309-A1 (CA)
Inventor: KOSTEDT WILLIAM LEONARD IV
IPC: C02F1/52
Filed: 2015-03-09
Abstract: A method of removing barium and naturally occurring radioactive material from produced water. The method includes pretreating the produced water having a pH in a range of from about 4.0 to about 10.0 with a sulfate source to form a suspension of barium sulfate, radium sulfate, or a combination thereof, treating the pretreated produced water with an anionic flocculant and gravitational])' separating the treated produced water from the barium sulfate, radium sulfate, or a combination thereof.
Patent CA-2947982-A1 (CA)
Inventor: ARNOLD SUSAN
IPC: A61K38/26
Filed: 2015-05-08
Abstract: La présente invention concerne un procédé de traitement de maladies ou de troubles associés à un dysfonctionnement de la protéine CFTR, y compris la fibrose cystique, par administration, d'agents thérapeutiques à base de peptide intestinal vasoactif stables et à effet durable. Ces agents comprennent un ou plusieurs peptides de type élastine et peuvent être administrés à une faible dose.
Patent CA-2948616-A1 (CA)
Inventor: DINU DANIEL
IPC: H05K9/00
Filed: 2015-05-13
Abstract: A cover assembly for covering and electrically insulating an electrical connection includes a joint body including a tubular inner sleeve and an integral semiconductor layer. The inner sleeve is formed of an elastically expandable, electrically insulating material and having an outer surface and opposed first and second terminal ends. The inner sleeve defines a through passage extending axially from a first end opening at the first terminal end of the inner sleeve to a second terminal end opening at the second end of the inner sleeve. The semiconductor layer is disposed on the outer surface of the inner sleeve and is formed of an electrically semiconductive material. The semiconductor layer extends axially from a first terminal end of the semiconductor layer to an opposing second terminal end of the semiconductor layer. The first terminal end of the semiconductor layer is spaced apart from the first terminal end of the inner sleeve a prescribed semiconductor truncation distance to define a tubular band of the outer surface that is not covered by the semiconductor layer.
Patent CA-2948879-A1 (CA)
Title: Fluid spraying system and method for a mass transit vehicle
Inventor: JACOB RICHARD
IPC: B61L5/04
Filed: 2016-11-17
Abstract: In an apparatus and method of automatically providing or withholding fluid from a power rail for a mass transit vehicle, during movement of a mass transit vehicle on a pathway in an uncovered (or exposed) area of the pathway, fluid, for example, anti-icing fluid, is caused to be provided to (or dispensed on) the power rail supplying power to the mass transit vehicle. During movement of the mass transit vehicle in a covered area of the pathway, the fluid is withheld from (or not dispensed on) the power rail. The changing from fluid being dispensed on the power rail to the fluid being withheld from the power rail, or vice versa, can be based on movement of the mass transit vehicle from the uncovered area of the pathway to the covered area of the pathway, or vice versa.
Patent CA-2949746-A1 (CA)
Title: Nacelle pour turboreacteur d'aeronef comprenant une tuyere secondaire a portes rotatives
Inventor: TISSOT SARAH
IPC: F02K3/04
Filed: 2015-05-20
Abstract: La présente invention concerne une nacelle pour turboréacteur, comprenant un capotage externe (3) comprenant une paroi interne définissant, avec une structure interne fixe, un canal annulaire (15) d'écoulement d'un flux d'air secondaire, et une tuyère (9) d'éjection dudit flux d'air secondaire, ladite tuyère comprenant : o au moins une ouverture (19), o au moins une portion extrême aval continue (21), en aval de ladite ouverture, o au moins une porte (17) mobile entre une position de fermeture et une position d'ouverture autorisant le passage d'une partie dudit flux d'air à travers ladite ouverture (19). La nacelle selon l'invention est remarquable en ce qu'elle comprend des moyens d'actionnement de la porte conformés, lors de leur activation depuis une position de fermeture vers une position d'ouverture de la porte, pour entraîner ladite porte en un mouvement combiné de translation vers l'amont de la nacelle et de rotation vers l'extérieur de la nacelle.
Patent CA-2952923-A1 (CA)
Inventor: PERU DEBORAH ANN
IPC: G01N21/359
Filed: 2014-07-24
Abstract: This application is directed to methods of assessing polymer deposition on dental surfaces using near infrared spectroscopy, providing a rapid and efficient method to screen for and identify optimal polymers for use in oral care formulations, (i) near infra red (IR) absorption of a dental substrate is measured in the absence of a polymer under test, and subsequently of the test sample comprising the dental substrate contacted with the test polymer. After washing or rinsing the test sample near IR of it is determined again (iii). The IR absorption of the test polymer itself is also measured (ii). Through the comparison of the three measurements (i), (ii), and (iii) the degree of deposition and retention of the test polymer on the test sample is determined.
Patent CA-2954702-A1 (CA)
Title: Methods and apparatuses for frequency spectrum assignment
Inventor: SOLDATI PABLO
IPC: H04W88/02
Filed: 2014-07-11
Abstract: The present invention relates to a network node and a user device for wireless communication systems. The network node comprises a transceiver, and a processor; wherein the transceiver is configured to transmit a frequency utilization signal comprising frequency utilization information associated with at least one available frequency spectrum segment of the wireless communication system; and receive a communication preference signal associated with at least one user device, wherein the communication preference signal comprises communication preference information for the at least one user device; and wherein the processor is configured to assign, for the at least one user device, at least one frequency spectrum segment for communication in the wireless communication system based on the communication preference information. The user device comprises a transceiver and a processor; wherein the transceiver is configured to receive a frequency utilization signal comprising frequency utilization information associated with at least one available frequency spectrum segment; and wherein the processor is configured to determine, based on the frequency utilization information, communication preference information for the user device; and the transceiver is further configured to transmit a communication preference signal comprising the communication preference information to at least one network node.
Patent CA-2955356-A1 (CA)
Inventor: BOYANOV BOYAN
IPC: C12Q1/68
Filed: 2015-07-14
Abstract: L'invention concerne un procédé de séquençage d'acide nucléique. Ce procédé peut comprendre les étapes consistant à (a) prendre une polymérase attachée à un capteur de charge d'un support solide; (b) prendre un ou plusieurs nucléotides, la présence du nucléotide pouvant être détectée par le capteur de charge; et (c) détecter l'incorporation du nucléotide dans un brin naissant complémentaire d'un acide nucléique matrice.
Patent CA-2957931-A1 (CA)
Inventor: POTAPENKO DMITRIY
IPC: G05B19/02
Filed: 2015-08-13
Abstract: Methods of treating an underground formation may include obtaining logging data for at least a section of a wellbore, treating a plurality of zones in at least a section of the wellbore using the multi-stage single-point fracturing operation, obtaining one or more of treatment data, flowback data, or production data for the treated plurality of zones, defining one or more dependencies between the obtained logging data and one or more of treatment data, flowback data, or production data, and using the dependencies to perform subsequent operations on the at least a section of a wellbore or in another wellbore. Methods may also include designing a completion string using dependencies defined from data obtained by performing a multi-stage single-point fracturing treatment on a plurality of zones in the at least a section of a wellbore.
Patent CA-2960131-A1 (CA)
Title: Brake cylinder maintaining reference
Inventor: CONNELL JASON
IPC: B60T15/18
Filed: 2014-09-08
Abstract: A brake cylinder maintaining system produces a brake cylinder reference pressure based on the difference between the brake pipe pressure and the auxiliary reservoir pressure and then feeds that pressure to a choke and a volume so that the ratio of the reference area of the choke to the volume of stored brake cylinder reference pressure is substantively equal to the ratio of a brake cylinder charging valve area to the brake cylinder volume. The resulting reference pressure may be used to adjust brake cylinder pressure by providing the reference pressure to a standard quick service limiting valve or to a relay that can selectively charge or exhaust the brake cylinder.
Patent CA-2960331-A1 (CA)
Title: Utilisation antibacterienne de salicylanilides halogenes
Inventor: DELAVENNE EMILIE FLORA AURORE
IPC: A61P31/04
Filed: 2015-09-08
Abstract: L'invention concerne un salicylanilide halogéné sélectionné entre le closantel, le rafoxanide, l'oxyclozanide et la niclosamide, et des dérivés de ceux-ci y compris des sels, des hydrates, des esters et similaires, pour une utilisation dans le traitement ou la prévention, par voie topique, d'infections provoquées par des bactéries Gram positif telles que Staphylococcus, notamment Staphylococcus aureus, et Streptococcus, en particulier Streptococcus pyogenes. Les bactéries à Gram positif traitées par les salicylanilides halogénés présentent une très faible fréquence d'apparition de mutants résistants en comparaison avec les antibiotiques à usage topique couramment utilisés.