baber/WOPTO huggingface dataset:
Patent MX-PA01009949-A (MX)
Title: ARYL AND HETEROARYL FUSED AMINOALKYL-IMIDAZOLE DERIVATIVES: SELECTIVE MODULATORS OF GABAa RECEPTORS.
Inventor: ROSEWATER DANIEL L
IPC: A61P43/00
Filed: 2000-03-31
Abstract: Disclosed are compounds of the formula: or the pharmaceutically acceptable non-toxic salts thereof wherein the A, B, C, D, X, R<SUB>1</SUB>, R<SUB>2</SUB>, R<SUB>3</SUB>, R<SUB>4</SUB>, R<SUB>5</SUB>, and R<SUB>6</SUB>, are variables defined herein, which compounds are highly selective agonists, antagonists or inverse agonists for GABAa brain receptors or prodrugs of agonists, antagonists or inverse agonists for GABAa brain receptors, and are therefore useful in the diagnosis and treatment of anxiety, Down Syndrome, sleep, cognitive and seizure disorders, depression, overdose with benzodiazepine drugs, and enhancement of memory and alertness.
Patent MX-PA01010260-A (MX)
Title: Magnesium dichloride-alcohol adducts, process for their preparation and catalyst components obtained therefrom.
Inventor: GOVONI GABRIELE
IPC: C08F10/00
Filed: 1998-03-23
Abstract: The present invention relates to MgCl2.mROH.nH2O adducts, where R is a C1-C10 alkyl, 2<=m<=4.2, 0<=n<=0.7, characterized by an X-ray diffraction spectrum in which, in the range of 2theta diffraction angles between 5° and 15°, the three main diffraction lines are present at diffraction angles 2theta of 8.8 ° 0.2°, 9.4 ° 0.2° and 9.8 ° 0.2°, the most intense diffraction lines being the one at 2theta=8.8 ° 0.2°, the intensity of the other two diffraction lines being at least 0.2 times the intensity of the most intense diffraction line. Catalyst components obtained from the adducts of the present invention are capable to give catalysts for the polymerization of olefins characterized by enhanced activity and stereospecificity with respect to the catalysts prepared from the adducts of the prior art.
Patent MX-PA01013193-A (MX)
Title: Adaptive protection for recloser control.
Inventor: MCELRAY JEFFREY L SR
IPC: H02H3/06
Filed: 2001-12-18
Abstract: A recloser is adaptively controlled so that it will operate in a manner responsive to prevailing conditions such as time of day, day of week, and/or load current. A protection setting group is stored in a memory accessible by the recloser controller, and contains a set of instructions for controlling the recloser based on the prevailing conditions. The prevailing conditions are continuously monitored, and the control of the recloser is based on the prevailing conditions and the protection setting group.
Patent MX-PA02001371-A (MX)
Title: Cleaning compositions.
Inventor: KREISCHER PIETER HUBERTUS
IPC: C11D17/06
Filed: 2000-07-24
Abstract: A cleaning composition formed into moulded bodies for use in for example fabric washing, dishware washing, stain removal and water softening incorporates disintegrant granules comprising a water insoluble inorganic material and a water-swellable agent which, in its anhydrous state, comprises no more than 20 % of the combined weight of said inorganic material.
Patent MX-PA02003202-A (MX)
Title: Process for obtaining a device of a retro reflective material with a radio frequency device.
Inventor: FRANCISCO MARTINEZ DE VELASCO
Filed: 2002-03-26
Abstract: The present invention refers to a process for demetallizing a retro reflective or reflective material with a radio frequency device, which consist in removing metal deposits adhered to the material by means of exposing the same to determined chemical solutions. The process is based on the flexographic, offset, screen printing methods or any method that uses printing rollers for transferring the chemical substance, in place of common inks, to the retro reflective or reflective material in order to subsequently insert the radio frequency device (aluminum or copper antenna) into the demetallized zone.
Patent MX-PA02003251-A (MX)
Title: Absorbent article having barrier sheet against the migration of the skin care composition.
Inventor: BRIAN FRANCIS GRAY
IPC: A61F13/15
Filed: 1999-10-01
Abstract: An absorbent article having a barrier sheet against a skin care composition is disclosed. The absorbent article has a body surface and a garment surface. The absorbent article comprises an absorbent core. At least a portion of the absorbent article has a skin care composition provided thereon. The absorbent article has a barrier sheet. The barrier sheet is treated to reduce the migration of the skin care composition therethrough.
Patent MX-PA02005913-A (MX)
Title: Use of wicking agent to eliminate wash steps for optical diffractionbased biosensors.
Inventor: KAYLOR ROSANN M
IPC: C40B60/14
Filed: 2000-12-12
Abstract: The present invention provides an inexpensive and sensitive system and method for detecting analytes present in a medium. The system comprises a diffraction enhancing element, such as functionalized micropsheres, which are modified such that they are capable of binding with a target analyte. Additionally, the system comprises a polymer film, which may include a metal coating, upon which is printed a specific, predetermined pattern of analytespecific receptors. Finally, the system includes a wicking agent which permits the system to be a single step system which avoids the necessity of any additional rinsing steps. Upon attachment of a target analyte to select areas of the polymer film, either directly or with the diffraction enhancing element, diffraction of transmitted andor reflected light occurs via the physical dimensions and defined, precise placement of the analyte. A diffraction image, such as a hologram, is produced which can be easily seen with the eye or optionally, with a sensing device.
Patent MX-PA02005952-A (MX)
Title: Chair.
Inventor: KINOSHITA YOJIRO
IPC: A47C3/026
Filed: 2001-10-09
Abstract: In a chair 1 having an upholstery member 7 fitted on a backrest portion or seat plate 4 serving as a portion adapted to contact a human body, upright portions 41 and elastic pieces 8 allowing their deflection in the direction in which the load of a human body contacting the chair works are provided and the upholstery member 7 is placed over the upright portions 41 and elastic pieces 8 so that the contacting portion of the seat portion or backrest portion is imparted with elasticity to ensure a better sitting comfort even if the upholstery member 7 lacks elasticity. <IMAGE>
Patent MX-PA02006450-A (MX)
Title: Modular anatomic fusion device.
Inventor: THALGOTT JOHN S
IPC: A61F2/30
Filed: 2002-06-27
Abstract: A modular fusion cage and tool for the insertion of the fusion cage is provided. The fusion cage includes a ramp member having superior and inferior bone contacting surfaces, and anterior and posterior sides. The ramp member is adapted to be positioned between adjacent vertebral bodies. The implant also includes a ring member slidably matable with the ramp member. The ring member includes superior and inferior bone contacting surfaces, and anterior and posterior sides. The implant according to the present invention is particularly useful for facilitating the safe and accurate insertion of the implant between adjacent vertebral bodies.
Patent MX-PA02009559-A (MX)
Title: Crystalline pharmaceutical.
Inventor: LECHUGA-BALLESTEROS DAVID
IPC: A61P/
Filed: 2001-03-21
Abstract: New crystalline forms of lopinavir are disclosed.
Patent MX-PA02010999-A (MX)
Title: Method for the preparation of polymeric micelle via phase separation of block copolymer.
Inventor: YI YIL WOONG
IPC: A61K31/337
Filed: 2001-05-11
Abstract: A method for preparing a biodegradable polymeric micellar composition using liquid polyethylene glycol as a phase separation medium comprising mixing an effective amount of a hydrophobic drug, an amphiphilic block copolymer and a phase separation medium comprising liquid poly(ethylene glycol), stirring and heating to give a solution; cooling and stirring the solution until it forms a polymeric micelle by phase separation; diluting the polymeric micelle solution in distilled water and then dialyzing it against excess water to remove the liquid polyethylene glycol; and freeze drying the dialyzed aqueous solution to give a polymeric micellar composition in a powdered state.
Patent MX-PA03000137-A (MX)
Title: Dna encoding human serine protease d-g.
Inventor: ANDRADE-GORDON PATRICIA
IPC: A61K48/00
Filed: 2001-06-08
Abstract: Here we describe the molecular identification of a cDNA encoding a novel serine protease we have termed D-G. The deduced amino acid sequence, and its alignment with other well characterized serine proteases clearly indicates that it is a member of the S1 serine protease family. We have found that the protease D-G mRNA is widely expressed in several tissues throughout the body including epidermis, fibroblasts, keratinocytes, colon, small intestine, stomach, lung, kidney, bone marrow, lymph node, thymus, ovary, prostate, uterus and spinal cord. Interestingly, this protease contains a hydrophobic stretch of amino acids which is a putative transmembrane near the NH2-terminus. Thus, this serine protease is thought to be synthesized as a type II integral protein. We expressed a soluble form of this novel human protease by inserting the portion of the protease D-G cDNA, encoding the catalytic domain, in a zymogen activation construct designed to permit the generic activation of heterologous serine protease catalytic domains. The result is an active preparation of protease D-G that has an activity against a subset of amidolytic substrates. This enzymatically active protease D-G preparation is now amenable to further biochemical analyses for the identification of physiological substrates as well as specific inhibitors.
Patent MX-PA03000456-A (MX)
Title: Device for mini-invasive ultrasound treatment of disc disease.
Inventor: LIDGREN LARS ARING
IPC: A61B6/12
Filed: 2001-07-16
Abstract: Device for miniinvasive ultrasound treatment of disc disease. A therapeutic ultrasound tranducer (2) is provided for treatment of the disc (5), of a patient (4) by generating an ultrasonic field (3), of which the temperature focus (F) is located in the disc (5), for heating thereof. The device comprises an optical navigating device (20) with a signal receiving or signal sending unit (32). A reference device (28) has a set position relative to the disc (5). The Therapeutic ultrasound transducer (2) is provided for insertion through the skin of the patient (4) and engagement of the disc (5), preferably anulus fibrosus (8), and it has a flexible wall with an ultrasound transmitting element provided within the flexible wall. Between the flexible wall and the ultrasound transmitting element there is located at least one cooling chamber (11) with cooling liquid for cooling the ultrasound transmitting element and the tissue closest to the therapeutic ultrasound transducer (2) and a temperature sensor is provided to measure the temperature in the disc (5), preferably anulus fibrosus (8).
Patent MX-PA03002038-A (MX)
Title: Installation tool for installing swage type threaded fasteners.
Inventor: FULBRIGHT DAVID J
IPC: B21J15/02
Filed: 2001-08-28
Abstract: A fastener system for multi-piece swage type fasteners, including a pin (12) and a collar (14), and providing a stump type fastener (10) constructed to be set as a pull type fastener with the fastener pin (12) having a threaded gripping portion (34) and including a compact installation tool (44) having a swage anvil (50) and a rotary threaded member (46) adapted to be threaded onto the threaded pull portion (34) of the pin (12) whereby a relative axial force is applied between the pin (12) and the collar (14) via the rotary threaded member (46) and swage anvil (50) to cause the anvil (50) to radially overengage the collar (14) to swage it into locking grooves (32) on the pin (12) and the pull portion (34) remaining on the pin (12) after installation and with the swage anvil (50) being connected to a piston rod (104) of a piston (80) for axially reciprocating movement for swaging the collar (14) with the rotary threaded member (46) being axially fixed and with the swage anvil (50) and rotary threaded member (46) being offset from the remainder of the tool (44) whereby the tool (44) can be used to install such fastener (10) in application of limited clearance.
Patent MX-PA03002040-A (MX)
Inventor: ROTHSCHILD MAX F
IPC: C12Q1/68
Filed: 2001-09-10
Abstract: Se divulgan marcadores genéticos para la calidad de la carne animal y eficiencia reproductiva, métodos para identificar tales marcadores y métodos para buscar animales para determinar a aquellos mas deseables para producir más litros y/o mejor calidad de carne y seleccionar preferiblemente a aquellos animales para futuros propósitos reproductivos. Los marcadores están basados en la presencia o ausencia de ciertos polimorfismos en el gen PRKA
Patent MX-PA03007489-A (MX)
Title: Optical bodies containing cholesteric liquid crystal material and methods of manufacture.
Inventor: POKORNY RICHARD J
IPC: G02B5/30
Filed: 2001-11-29
Abstract: An optical body includes a substrate and a cholesteric liquid crystal layer disposed on the substrate. The cholesteric liquid crystal layer has a non-uniform pitch along a thickness direction of the layer and comprises a crosslinked polymer material that substantially fixes the cholesteric liquid crystal layer. The crosslinking hinders diffusion of cholesteric liquid crystal material within the cholesteric liquid crystal layer. In other methods of making an optical body, a reservoir of chiral material is provided during the process over a first cholesteric liquid crystal layer to diffuse into the layer and provide a non-uniform pitch. Alternatively, two coating compositions can be disposed on a substrate where the material of the first coating composition is not substantially soluble in the second coating composition.
Patent MX-PA03009187-A (MX)
Title: Proton-conducting membrane and the use thereof.
Inventor: SANSONE MICHAEL J
IPC: H01M8/1086
Filed: 2002-04-09
Abstract: Proton-conducting polymer membranes based on polyazoles are obtained by reacting aromatic tetra-amine and aromatic dicarboxylic acid, dissolving the prepolymer in polyphosphoric acid, heating the solution to form a polyazole polymer and then coating onto a support as usual. Proton-conducting polymer membranes based on polyazoles, obtained by (A) reacting aromatic tetra-amino compounds with aromatic dicarboxylic acids or their esters at up to 350 (preferably up to 300) [deg]C, (B) dissolving the resulting solid prepolymer in polyphosphoric acid, (C) heating the solution under inert gas at up to 300 (preferably 280) [deg]C to form a solution of polyazole polymer, (D) forming a membrane from the solution on a support and (E) treatment to form a self-supporting membrane. Independent claims are also included for (a) electrodes with a proton-conducting polyazole-based coating obtained by performing stages (A) to (C) as above and then (D) forming a layer on an electrode by coating with the polyazole solution and (E) treatment of the layer; (b) membrane-electrode units containing at least one electrode (especially as in (a)) and at least one membrane as described; and (c) fuel cells containing these membrane-electrode units.
Patent MX-PA03009954-A (MX)
Title: Ef-tu binding agent as antibacterial agent.
Inventor: FRANK MAYER
IPC: A61P31/04
Filed: 2002-04-22
Abstract: The invention relates to the use of substances, binding to the bacterial translation factor EF-Tu, to prevent the formation of a cytoskeleton in bacterial cells and for production of anti-bacterial agents. The invention further relates to anti-bacterial agents, comprising partial sections of the amino acid sequences of the domains 2 and/or 3 of a bacterial EF-Tu protein, preferably with a length of 4-20 amino acids.
Patent MX-PA03010066-A (MX)
Title: Battery powered humidity indicator.
Inventor: BRIAN L CUNKELMAN
IPC: G01N25/56
Filed: 2003-11-03
Abstract: The present invention provides an apparatus that is used to measure relative humidity, such apparatus comprises a housing having a first end and a second end. There is a humidity sensor disposed at the first end of the housing for measuring the humidity in the air and a temperature sensor also disposed at the first end of the housing for measuring ambient temperature. The apparatus has an electronics portion in direct electrical communication with the humidity sensor and the temperature sensor for computing a relative humidity and a dewpoint temperature. The electronics portion is disposed within a center portion of the housing. There is, further, a battery that is in electrical communication with the electronics portion, the humidity sensor and the temperature sensor for providing power to the apparatus. Such battery is disposed in the center portion of the housing of the apparatus. The apparatus has a display means that is in electrical communication with the electronics portion and with the battery for displaying such relative humidity and such dew point temperature as determined by the electronics portion. The display means is disposed at a second end of said housing.
Patent MX-PA03010612-A (MX)
Title: Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues.
Inventor: XIAO-SHU HE
IPC: C07D317/58
Filed: 2002-05-21
Abstract: Melanin concentrating hormone receptor ligands (especially 1-benzyl-4-aryl-piperazines, 1-benzyl-4-aryl-piperidines and related compounds), capable of modulating MCH receptir activity, are provided. Such ligands may be used to modulate MCH binding to MCH receptors in vivo or in vitro, and are particularly useful in the treatment of a variety of metabolic, feeding and sexual disorders in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting MCH receptors (e.g., receptor localization studies).
Patent MX-PA03011463-A (MX)
Title: Xenogenic oligoor/and polyribonucleotides as agents for the treatment of malignant tumours.
Inventor: BARBARA MEISRIEMLER
IPC: A61K47/48
Filed: 2002-06-26
Abstract: The invention relates to xenogenic oligo and/or polyribonucleotides as agents for the treatment of malignant tumours. The invention also relates to the use of said xenogenic oligo and/or polyribonucleotides in the production of medicaments for the treatment of malignant tumours.
Patent MX-PA04004237-A (MX)
Title: Post-treatment for metal coated substrates.
Inventor: JAMES L GREEN III
IPC: C23C22/83
Filed: 2002-11-05
Abstract: An aqueous composition for post-treating metal coated substrates such as cadmium-plated steel or zinc-nickel coated substrates and the process for using said composition to improve the corrosion-resistance, abrasion, and adhesion bonding properties of the metal coatings. The composition comprising an acidic aqueous solution having a pH ranging from about 2.5 to 4.5 containing effective amounts of trivalent chromium salts, an alkali metal hexafluorozirconate, at least one alkali metal fluorocompound, and effective amounts of water soluble thickeners and/or surfactants.
Patent MX-PA04004432-A (MX)
Title: A dual band phased array employing spatial second harmonics.
Inventor: GRIFFIN K GOTHARD
IPC: H01Q5/357
Filed: 2002-11-08
Abstract: A directive antenna operable in multiple frequency bands includes an active antenna element and at least one passive antenna element parasitically coupled to the active antenna element. The passive antenna element(s) have length and spacing substantially optimized to operate at (i) a fundamental frequency associated with the active antenna element and (ii) a higher resonant frequency related to the fundamental frequency. Spatial-harmonic current-distributions of the passive antenna elements are used to create the multiple frequency bands of operation. The directive antenna also includes devices operatively coupled to the passive antenna element(s) to steer an antenna beam formed by applying a signal at the fundamental resonant frequency, higher resonant frequency, or both to the active antenna element to operate in the multiple frequency bands.
Patent MX-PA04005151-A (MX)
Title: Therapeutic compounds.
Inventor: JIAN-MIN FU
IPC: A61P25/24
Filed: 2002-11-26
Abstract: The present invention provides compounds of Formula (I): wherein X, R1, R2, R3, R4, R5, and R6 have any of the values defined in the specification, as well as pharmaceutical compositions comprising the compounds. The invention also provides therapeutic methods as well as processes and intermediates useful for preparing compounds of Formula (I).
Patent MX-PA04008882-A (MX)
Title: Steel product and method for manufacturing.
Inventor: SRSEN BRIAN J
IPC: C22C38/24
Filed: 2003-03-11
Abstract: A method for providing a steel product having a surface hardness of between about 360 Bhn and 420 Bhn is provided. The method includes steps of providing a steel product from a steel product comprising at least about 96 wt.% iron and between about 0.24 wt.% and about 0.30 wt.% carbon, heating the steel product to at least its austentizing temperature, quenching to below its martinsite finish temperature, and tempering the steel product at a temperature of at least about 800 degree F. Steel products prepared by this method are described.
Patent MX-PA05000011-A (MX)
Title: Stable liquid parenteral parecoxib formulation.
Inventor: SCHARTMAN RICHARD
IPC: A61P25/00
Filed: 2003-06-18
Abstract: A parenterally deliverable pharmaceutical composition comprises a water soluble parecoxib salt, in dissolved and/or solubilized form in a solvent liquid that comprises water and one or more nonaqueous solubilizer(s). Valdecoxib formed by conversion of parecoxib is solubilized by the nonaqueous solubilizer(s), which are substantially inert with respect to such conversion. The composition has parecoxib salt stabilizing means for inhibiting precipitation of parecoxib free acid. The composition is storage stable and is suitable for parenteral administration to treat a COX-2 mediated condition or disorder.
Patent MX-PA05001603-A (MX)
Title: Monocyclic derivatives as matrix metalloproteinase inhibitors.
Inventor: PICARD JOSEPH ARMAND
IPC: C07D237/14
Filed: 2003-08-03
Abstract: This invention provides compounds defined by Formula (I) or a pharmaceutically acceptable salt thereof, wherein R', Q, D, V', m, and R2 are as defined in the specification. The invention also provides pharmaceutical compositions comprising a compound of Formula (I), or a pharmaceutically acceptable salt thereof, as defined in the specification, together with a pharmaceutically acceptable carrier, diluent, or excipient. The invention also provides methods of inhibiting an MMP-13 enzyme in an animal, comprising administering to the animal a compound of Formula (I), or a pharmaceutically acceptable salt thereof. The invention also provides methods of treating a disease mediated by an MMP-13 enzyme in a patient, comprising administering to the patient a compound of Formula (I), or a pharmaceutically acceptable salt thereof, either alone or in a pharmaceutical composition. The invention also provides methods of treating diseases such as heart disease, multiple sclerosis, osteo- and rheumatoid arthritis, arthritis other than osteo- or rheumatoid arthritis, cardiac insufficiency, inflammatory bowel disease, heart failure, age-related macular degeneration, chronic obstructive pulmonary disease, asthma, periodontal diseases, psoriasis, atherosclerosis, and osteoporosis in a patient, comprising administering to the patient a compound of Formula (I), or a pharmaceutically acceptable salt thereof, either alone or in a pharmaceutical composition. The invention also provides combinations, comprising a compound of Formula (I), or a pharmaceutically acceptable salt thereof, together with another pharmaceutically active component as described in the specification.