baber/WOPTO huggingface dataset:
Patent CA-2642738-A1 (CA)
Title: Pi-3 kinase inhibitors and methods of their use
Inventor: COSTALES ABRAN
IPC: C07D471/04
Filed: 2007-02-14
Abstract: Phosphatidylinositol (PI) 3 kinase inhibitor compounds, their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, phospholipid kinases, G-protein coupled receptors, and phosphatases.
Patent CA-2644441-A1 (CA)
Inventor: CORCORAN NIALL
IPC: A61P25/28
Filed: 2007-03-29
Abstract: The present invention relates to the use of selenate or a pharmaceutically acceptable salt thereof in methods and compositions for enhancing the activity of the protein phosphatase PP2A. Methods of reducing phosphorylation of tau protein, inhibiting activity of GSK3 and treating or preventing neurodegenerative diseases are also described.
Patent CA-2645823-A1 (CA)
Title: Systeme therapeutique transdermique contenant de la norelgestromine pour la contraception et la substitution hormonale
Inventor: EIFLER RENE
IPC: A61K9/70
Filed: 2007-10-10
Abstract: La présente invention concerne un système thérapeutique transdermique destiné à l'application de la substance active norelgestromine sur la peau, facultativement en combinaison avec des AEstrogènes. Elle concerne en outre l'utilisation de ces systèmes pour la contraception hormonale ainsi que pour la thérapie de substitution hormonale.
Patent CA-2646627-A1 (CA)
Title: Rosiglitazone hydrochloride hemihydrate
Inventor: WIESER JOSEF
IPC: A61K31/427
Filed: 2007-03-21
Abstract: 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione, hydrochloride hemihydrate (rosiglitazone hydrochloride hemihydrate) characterized in that: (i) comprises water in the range of from about 1.0 to about 2.5% w/w; and (ii) provides an infrared spectrum containing peaks at about 3504, 2751, 1688, 1601 and 1215 cm-1; and/or (iii) provides an X-ray powder diffraction (XRPD) pattern containing peaks at about 12.5, 17.1, 21.3, 26.7, 27.7 °2 ¸; a process for preparing such a compound, a pharmaceutical composition containing such a compound and the use of such a compound in the treatment and/or prophylaxis of diabetes mellitus.
Patent CA-2646937-A1 (CA)
Inventor: GREEN RONALD
IPC: F16L37/00
Filed: 2007-03-21
Abstract: A fluid quick connect fluidually couples a conduit having an attachment groove for a retainer on a quick connect housing. The housing includes circumferential Iy spaced fingers of each which include a barbed end that engages a corresponding internal groove within a valve housing. The housing fits over conduit and is aligned with the attachment groove. The end of the conduit may be closed and a cut-off indicator provided to enable cut-off of the sealed end after a system pressure test. Complementary anti-rotation features may be provided on the conduit and one of quick connect housing and a valve housing.
Patent CA-2655914-A1 (CA)
Inventor: CRESSMAN ROBERT F
IPC: C12N15/82
Filed: 2007-06-25
Abstract: Compositions and methods related to transgenic glyphosate/ALS inhibitor-tolerant soybean plants are provided. Specifically, soybean plants having a 3560.4.3.5 event which imparts tolerance to glyphosate and at least one ALS-inhibiting herbicide are provided. The soybean plant harboring the 3560.4.3.5 event at the recited chromosomal location comprises genomic/transgene junctions having at least the polynucleotide sequence of SEQ ID NO: 10 and/or 11. The characterization of the genomic insertion site of the 3560.4.3.5 event provides for an enhanced breeding efficiency and enables the use of molecular markers to track the transgene insert in the breeding populations and progeny thereof. Various methods and compositions for the identification, detection, and use of the soybean 3560.4.3.5 events are provided.
Patent CA-2660917-A1 (CA)
Title: Process for producing benzoxazine derivative and production intermediate thereof
Inventor: NAGAI TOMOYUKI
IPC: C07D498/06
Filed: 2000-09-07
Abstract: A process which is industrially advantageous in producing antibacterial agents. An industrially advantageous process for producing an intermediate useful in producing antibacterial agents is provided by producing compound (VI-a) in according with the following reaction schema: (see formula I)(see formula II-a)(see formula III-a)(see formula III-1-a) (see formula III-2-a)(see formula IV-a)(see formula IV-a)(see formula V-a) (see formula VI-a)(see formula VII-a).     A process for producing the compound represented by the above formulae and production intermediates thereof.
Patent CA-2661015-A1 (CA)
Inventor: KONIETZNI HANS-JOACHIM
IPC: H01L21/02
Filed: 2007-08-09
Abstract: A process for regenerating electrolytes containing high sodium chloride concentrations for reuse in the production of an electrochemical polishing process of aluminum surfaces.
Patent CA-2662532-A1 (CA)
Inventor: NORMAN SCOTT A
IPC: G06Q50/22
Filed: 2009-04-15
Abstract: An apparatus and method are provided employing radio frequency identification and temperature detection tags to monitor the identification and temperature and the transfer and the storage of neonate feeding substrates such as neonate formula or breast milk and the like throughout a hospital and neonate care unit the apparatus includes a refrigeration and a heating and cooling unit for storing and making temperature modifications to the to neonate feeding substrate and which apparatus are used in the tracking of the substrate during the course of warming and/or refrigeration and/or transport of the substrate to different locations within a hospital or hospital neonate intensive care unit.
Patent CA-2663628-A1 (CA)
Inventor: GOESSING ROLF
IPC: F15B21/0427
Filed: 2008-06-19
Abstract: The present invention provides a device and a method for regulating a temperature (T) of hydraulic fluid in at least one hydraulic circuit (2) of an aircraft (1). In this case the temperature (T) of the hydraulic fluid is regulated so that it is above an adjustable minimum temperature limit value {Tmin) of approximately 20°C, for example, at all times.
Patent CA-2664829-A1 (CA)
Title: Furniture closure
Inventor: HAKEMANN FRITZ
IPC: F25D23/02
Filed: 2007-11-20
Abstract: The invention relates to a furniture closure for doors, shutters and drawers, in particular for cabinets and the like in the vehicle sector. In order to provide a furniture closure which, while being particularly straightforward to design and produce, ensures sealed and secured closure of doors, shutters (3) and drawers, a profile rail (5) having a seal (6), a grip strip and a locking element (7) is arranged along the peripheral region thereof and can be pivoted about a horizontal axis (23). The seal (6) has a spring force which retains the locking element (7) in the closure position and can be compressed for the opening position.
Patent CA-2666275-A1 (CA)
Title: Cyclopropyl-piperazine compounds as calcium channel blockers
Inventor: PAJOUHESH HASSAN
IPC: A61K31/5377
Filed: 2007-10-12
Abstract: Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted N-type calcium channel activity are disclosed. Specifically, a series of compounds containing both a piperazine ring and a cyclopropyl ring are disclosed of the general formula (I) where X1 and X2 are linkers.
Patent CA-2667464-A1 (CA)
Title: Cement silo structure for mining machine
Inventor: KANSOLA MARTTI
IPC: E21D20/02
Filed: 2007-11-01
Abstract: The invention relates to a cement silo structure for a mining machine comprising a mixer (9), a cement silo (10) for cement and a feed apparatus (11) for feeding cement to the mixer (9). The cement silo (10) is a separate unit that may be transferred by means of transfer means between a use position on top of the mining machine and a filling position that differs from the use position.
Patent CA-2669653-A1 (CA)
Inventor: VAN DER LELY ALEXANDER
IPC: A01K9/00
Filed: 2007-11-26
Abstract: A system and method for producing milk is disclosed in which the milk from a single animal is handled and processed separately from milk produced by other animals. On packaging the processed product, an indication specific to that animal may be included on the package.
Patent CA-2669702-A1 (CA)
Title: Microwave cooking tray with pop-up legs
Inventor: PARYSEK RICHARD M
IPC: B65D5/18
Filed: 2009-06-19
Abstract: A microwave cooking tray includes pop-up legs. The microwave cooking tray is formed from a blank including a main panel, at least two leg portions, each leg portion having a first panel connected to the main panel by a first fold line, a second panel connected to the first panel by a second fold line, and a third panel connected to the second panel by a third fold line, and an aperture located on each of the first fold line between the main panel and each of the first panels. When assembled each of the third panels lies flat against an underside of the main panel, such that each of the third panels reinforces the main panel, and the first panel and second panel extend downward from the underside of the main panel to form triangular legs resting on an edge.
Patent CA-2670131-A1 (CA)
Title: Electrolytic system and method for enhanced release and deposition of sub-surface and surface components
Inventor: FAULDER DAVID D
IPC: E21B43/00
Filed: 2007-11-19
Abstract: The present electrolytic system and method for extracting components includes a means for providing a carrier fluid; a means for providing a pair of electrodes interposed by a permeable membrane to create a first channel and a second channel; a means for flowing the carrier fluid through the first and second channel; a means for applying a voltage to the pair of electrodes to produce a first ionized carrier fluid in the first channel and a second ionized carrier fluid in the second channel; a means for injecting at least one of the first ionized carrier fluid and the second ionized carrier fluid into the subsurface reservoir to release the components; and a means for recovering the at least one of the first ionized carrier fluid and the second ionized carrier fluid and the components from a subsurface strata or ex-situ mineral deposit.
Patent CA-2670945-A1 (CA)
Title: Verrouillage mecanique de panneaux de plancher
Inventor: PERVAN DARKO
IPC: E04F15/04
Filed: 2007-09-24
Abstract: On décrit des panneaux de plancher (1, 1') munis d'un système de verrouillage mécanique sur les bords longs (5a, 5b) et les bords courts (4a, 4b) assurant une installation avec inclinaison des bords longs. Le système de verrouillage des bords courts comporte une languette mobile qui se déplace sensiblement dans un sens, d'une position non verrouillée à une position verrouillée définitive.
Patent CA-2671106-A1 (CA)
Title: Nonwoven fibrous multiply fabric and method and plant for producing the fabric
Inventor: ANDERSEN JENS OLE BROECHNER
IPC: D04H1/425
Filed: 2009-07-06
Abstract: A nonwoven fibrous multiply fabric comprises a first ply (2) of a mixture of cellulose fibres (6) and synthetic fibres (7), a second ply (3) of a mixture of cellulose fibres (6) and super absorbent powder (8), and a third ply (4) of cellulose fibres (6) only. A method for producing the fabric is carried out by means of a plant comprising an endless wire mesh screen, a first dry-forming stage (11) for forming the first ply (2) on the endless wire mesh screen, a first pair of rollers (14) for compacting the first ply (2), a second dry-forming stage for forming the second ply (3) on top of the first ply (2), a second pair of rollers (15) to form a coherent web (2,3,4) by compacting the plies (2,3,4) between the said rollers (15), a latex applying stage (16) for applying latex (5) to the web (2,3,4), a heating stage (17) for heating the web (2,3,4), a moistening stage (18) for moistening the web (2,3,4), a third pair of rollers (19) for embossing the web (2, 3, 4) on the side with the third ply (4), and a cooling stage (22) for cooling the web (2,3,4). A  nonwoven fibrous multiply fabric having an excellent strength, absorbency and durability can be performed to a low price by means of the simple and effectively functioning method and plant.
Patent CA-2672367-A1 (CA)
Title: 3-h-pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
Inventor: BOEMER ULF
IPC: A61P29/00
Filed: 2007-12-14
Abstract: The invention relates to 3-H-pyrazolopyridines according to the general formula (I) in which A, B, D, E, Ra, R1, R2, R3, R4, R5 and q are as defined in the claims, and salts, N-oxides, solvates and prodrugs thereof, to pharmaceutical compositions comprising said 3-H-pyrazolopyridine compounds, to methods of preparing said 3-H-pyrazolopyridines, to intermediate compounds useful in said methods, to uses of said intermediate compounds in the preparation of said 3-H-pyrazolopyridines, as well as to uses of said 3-H-pyrazolopyridines for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth, wherein the compounds effectively interfere with Tie2 signalling.
Patent CA-2673607-A1 (CA)
Title: Universal tumor cell vaccine for anti cancer therapeutic and prophylactic utilization
Inventor: FAKHRAI HABIB
IPC: A61K39/00
Filed: 2007-12-20
Abstract: The invention provides a composition for stimulating an immune response in a patient having different types of cancer including those having adenocarcinoma comprising a combination of allogeneic tumor cells and / or tumor stem cells that are selected on the basis of secreting at least one immunosuppressive agent, e.g., TGF-.beta., and that are genetically modified to reduce or inhibit the expression of said at least one immunosuppressive agent, e.g., TGF-.beta., and that collectively express a spectrum of tumor associated antigens representative of colon, breast, lung, prostate, pancreas, kidney, endometrium, cervix, ovary, thyroid, and other glandular tissue carcinomas, as well as squamous, melanoma, central nervous system, and lymphomas and a physiologically acceptable carrier. The adenocarcinoma can be, for example, colon, breast, lung, prostate, pancreas, kidney, endometrium, cervix, ovary, thyroid, or other glandular tissue, as well as squamous, melanoma, central nervous system, and lymphomas. The invention also provides a composition containing said combination of allogeneic tumor cells and or tumor stem cells and an allogeneic cell expressing a cytokme or an antibody that inhibits an immune suppressive molecule.
Patent CA-2673657-A1 (CA)
Inventor: O'NEIL KARYN T
IPC: A61P3/04
Filed: 2007-12-21
Abstract: The present invention provides to at least one novel human GLP-I receptor agonist, or specified portion or variant, including isolated nucleic acids that encode at least one GLP-I receptor agonist, or specified portion or variant, GLP-I receptor agonist, or specified portion or variants, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including the use of long acting GLP-I receptor agonists to improve insulin sensitivity or lipid profiles in obesity and related therapeutic and/or diagnostic compositions, methods and devices.
Patent CA-2674237-A1 (CA)
Inventor: XU XIANG
IPC: C07D409/14
Filed: 2007-12-21
Abstract: L'invention concerne la fourniture de composés d'hétérocycloalkyloxybenzamide N-substitués, ainsi que des compositions pharmaceutiques et des procédés d'utilisation. Un mode de réalisation de la présente invention est un composé ayant la structure (I), dans laquelle R1, R2, R3, R4, T, n, w et x sont tels que décrits dans le présent document. Dans certains modes de réalisation de la présente invention, un composé selon la présente invention active la voie AMPK, et peut être utilisé pour traiter des troubles et des états d'origine métabolique.
Patent CA-2677610-A1 (CA)
Inventor: PUIG DURAN CARLOS
IPC: C07D215/26
Filed: 2008-02-08
Abstract: The present invention is directed to crystalline mononapadisylate and/or heminapadisylate salts of 5-(2-([6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one having the formula (I): ( see formula I) and pharmaceutically acceptable solvates thereof.
Patent CA-2677939-A1 (CA)
Title: Method and system for removing manganese from waste liquors
Inventor: DUTERQUE JEAN-PAUL RAYMOND
IPC: C02F1/52
Filed: 2008-01-25
Abstract: A method and system of removing or decreasing waste liquor manganese concentration to less than about 1 mg/L total manganese without the precipitation of significant amounts of magnesium. The method and system include steps for treating the waste liquor using three separate circuits in which in the first circuit, manganese is reduced, for example, from about 2 g/L to <500 mg/L using pH adjustment with a suitable neutralizing agent; and in the second circuit, the final target manganese level is achieved by oxidative precipitation using a suitable oxidizing agent. Part of the precipitated manganese product, e.g., MnO2, is recycled to the oxidative precipitation circuit as seed and the balance proceeds to a third circuit wherein the precipitated manganese product is re-dissolved, and then recycled to the first neutralization circuit. In the first neutralization circuit and the second oxidative precipitation circuit, the process conditions are selected to minimize the precipitation of magnesium, e.g., Mg(OH)2.
Patent CA-2679464-A1 (CA)
Title: System and method of blocking malicios web content
Inventor: HUBBARD DAN
IPC: G06F17/30
Filed: 2008-01-30
Abstract: Certain embodiments provide for systems and methods of monitoring data sent from a requested device to a requesting device and removing certain portions of the data such as malicious or otherwise objectionable content. Objectionable content may include, for example, potentially executable web content. In certain embodiments, the systems and methods remove uniform resource locator (URL) links from the intercepted data which point to web pages having malicious or otherwise objectionable content.
Patent CA-2679898-A1 (CA)
Title: Multi-component expandable supportive bifurcated endoluminal grafts and methods for using same
Inventor: BENARY RAFI
IPC: A61F2/06
Filed: 2008-03-05
Abstract: A multiple-component expandable endoluminal system for treating a lesion at a bifurcation including a self expandable tubular root member having a side-looking engagement aperture, a self expandable tubular trunk member comprising a substantially blood impervious polymeric liner secured therealong; both having a radially compressed state adapted for percutaneous intraluminal delivery and a radially expanded state adapted for endoluminal support.
Patent CA-2680267-A1 (CA)
Title: Method and apparatus for electrophoretic separation of solids and water from oil based mud
Inventor: MCCOSH KAREN
IPC: B03C5/00
Filed: 2008-03-06
Abstract: A method of treating an invert emulsion drilling fluid, the method including pumping the drilling fluid to an electrophoresis unit that includes a positively charged electrode and a negatively charged electrode, applying a voltage between 200 V and 5000 V across the two electrodes to deposit water and solids on one of the charged electrodes, and removing deposited solids and water from the collection electrode is disclosed. An apparatus for treating an invert emulsion drilling fluid, the apparatus including a bath, a drum disposed in the bath, a power supply capable of applying a voltage between the housing and the drum in the range of 200 V to 5000 V, a motor coupled to the drum to rotate the drum at a predetermined speed, and a scraper having a first position in which the scraper contacts the rotating drum to remove deposited solids and water and a second position in which the scraper is retained away from the drum is also disclosed.
Patent CA-2682284-A1 (CA)
Inventor: FISHER PETER H
IPC: H02J17/00
Filed: 2007-06-11
Abstract: L'invention concerne un appareil destiné à être utilisé pour un transfert d'énergie sans fil. Ledit appareil comporte une première structure de résonateur conçue pour transférer de l'énergie sans rayonnement et d'une deuxième structure de résonateur située à une distance supérieure à la distance habituelle d'une deuxième structure de résonateur. Le transfert d'énergie sans rayonnement est favorisé par un couplage d'une queue évanescente de champ résonnant de la première structure de résonateur, et d'une queue évanescente de champ résonnant de la deuxième structure de résonateur.
Patent CA-2683089-A1 (CA)
Inventor: ONISHI YOSHIYUKI
IPC: A61P35/00
Filed: 2008-04-02
Abstract: A novel fused bicyclic heteroaryl derivative, which has a good hypoglycemic effect and treats sugar and lipid metabolic disorders or diseases mediated by peroxisome proliferator-activated receptor (PPAR) .gamma. and/or prevents the onset of these diseases, or a pharmacologically acceptable salt thereof. A compound having the following general formula (I) or a pharmacologically acceptable salt thereof: [Chemical formula 1] (I) wherein R1 represents a C1-6 alkyl group, a C6-10 aryl group optionally substituted by one to five groups independently selected from the substituent group a, etc.; R2 represents a C1-6 alkyl group; R3 represents a C6-10aryl group optionally substituted by one to five groups independently selected from the substituent group a, etc.; Q represents a group represented by the formula =CH- or a nitrogen atom; and the substituent group a includes a halogen atom, a C1-6alkyl group, a C1-6 hydroxyalkyl group and so on.
Patent CA-2683296-A1 (CA)
Title: Fire retardant-impregnated cellulose board, process of manufacture thereof and uses thereof
Inventor: BAROUX DANIEL
IPC: D21J1/00
Filed: 2009-10-22
Abstract: A board comprising dried, fire retardant-impregnated cellulose material. The board may be essentially rigid or a sponge depending on the size of the voids in the board. The boards are preferably made from particulate cellulose material using a void-creating salt and an aqueous fire retardant. The boards are of value in the production, for example, of wallboard and insulation wrapping.
Patent CA-2683332-A1 (CA)
Inventor: AGAN BENNY E
IPC: H01B7/22
Filed: 2009-10-22
Abstract: A metal-clad cable having a plurality of spaced apart labels. The labels have coded information about the cable and are conductive and/or include a plurality of openings so as to assure conductivity between an outer sheath of the metal-clad cable and a terminating assembly connector member coupled thereto.
Patent CA-2685132-A1 (CA)
Inventor: BARNOY SHOSHANA
IPC: A61K39/02
Filed: 2008-04-25
Abstract: Shigella vaccine strains whose primary attenuating feature is deletion of the virG(icsA) gene and additional two or more deletions in setAB(shET1), senA(shET2), senB(shET2- 2), stxAB, and msbB2 genes. Thus, the vaccine strain will have three or more deletions in the identified genes, will be safer, and will reduce or eliminate symptoms of fever and diarrhea in humans. The following specific vaccine strains have been constructed: WRSS3 (.DELTA.senA, .DELTA.senB, .DELTA.virG, .DELTA.msbB2), WRSf2G15 (.DELTA.virG, .DELTA.setAB, .DELTA.senA, .DELTA.senB, .DELTA.msbB2), and WRSd5 (.DELTA.virG, .DELTA. stxAB, .DELTA.senA, .DELTA.senB, .DELTA.msbB2).