baber/WOPTO huggingface dataset:
Patent UY-26043-A1 (UY)
Title: Acidos oxamicos y derivados como ligandos de receptores tiroideos
Inventor: CHIANG YUAN CHING PHOEBE
IPC: C07C235/74
Filed: 2000-02-29
Abstract: Ligandos de receptores tiroideos y, más particularmente, ácidos oxámicos y sus derivados, compuestos de fórmula (I), en donde: R1, R2 y R3 es independientemente hidrógeno, halógeno, alquilo, trifluorometilo, CN, OCF3 u O-alquilo; R4 es hidrógeno, alquilo opcionalmente sustituido; o R3 y R4 pueden tomarse conjuntamente para formar un anillo carbocíclico A de fórmula -(CH2)b- o un anillo heterocíclico A seleccionado entre un grupo de compuestos; R5 es flúor, hidroxi, alcoxi o OC(O)R9; o R4 y R5 pueden tomarse conjuntamente para formar un anillo heterocíclico B seleccionado entre un grupo de compuestos; R6 es hidrógeno, halógeno, alquilo o trifluorometilo; R7 es hidrógeno o alquilo; R8 es OR9 o NR19R20; W es O, S(O)d, CH2 o NR9. Por ejemplo: ácido N-(3-cloro-4-(3-ciclopropilsulfamoil-4-hidroxi-fenoxi)-5-metil-fenil)-oxámico. También se proporcionan composiciones farmacéuticas que contienen tales compuestos, profármacos, isómeros o sales farmacéuticamente aceptable de los mismos, y procedimientos, composiciones farmacéuticas y estuches para el tratamiento de la obesidad, hiperlipidemia, glaucoma, arritmia cardíaca, tratornos cutáneos, enfermedad del tiroides, hipotiroidismo y trastornos y enfermedades relacionadas tales como diabetes mellitus, aterosclerosis, hipertensión, enfermedad cardíaca coronaria, hipercolesterolemia, depresión y osteoporosis
Patent UY-27641-A1 (UY)
Title: Composiciones farmacéuticas de dispersiones amorfas de fármacos y materiales que forman microfases lipófilas
Inventor: DWAYNE FRIESEN
IPC: A61K47/14
Filed: 2003-01-31
Abstract: Una composición farmacéutica comprende una dispersión amorfa sólida que comprende un fármaco de baja solubilidad y un polímero que aumenta la concentración y un material que forma una microfase lipófila. Alternativamente, se administran conjuntamente una dispersión amorfa sólida que comprende un fármaco de baja solubilidad y un polímero que aumenta la concentración con un material que forma la microfase lipófila a un entorno de uso in vivo.
Patent UY-27859-A1 (UY)
Title: Conjunto motriz hibrido para propulsar automoviles con eficiencia y baja contaminacion
Inventor: LACORTE JUAN JOSE CASELLA DE
Filed: 2003-06-18
Abstract: Aparato eletro mecánico para utilización en vehículos autopropulsados. La tracción es generada por uno o más motores eléctricos controlados por dispositivos electrónicos de estado sólido de alta eficiencia a partir de una batería de acumuladores. Un motor de combustión interna de tamano pequeno trabaja casi siempre en el punto de máxima eficiencia y potencia cargando con un generador eléctrico a las baterías suministrando la potencia promedio necesaria. Se consigue alta eficiencia del conjunto, bajas emisiones y gran autonomía comparado a los vehículos exclusivamente eléctricos y los convencionales.
Patent UY-28105-A1 (UY)
Title: Derivados de indazol como antagonistas del crf
Inventor: OZANG COUNDE
IPC: C07D231/56
Filed: 2003-11-28
Abstract: Esta invención se refiere a compuestos que son en general antagonistas de receptores del factor CRF-1 y que se ajustan a la fórmula I o a la fórmula II: en la que R1 es arilo o heteroarilo eventualmente sustituido, R1 y R2 tienen el significado definido en la descripción; o isómeros individuales, mezclas racémicas o no racémicas de isómeros o sales farmacéuticamente aceptables de los mismos. a invención se refiere además a procesos para obtener dichos compuestos, a composiciones farmacéuticas que contienen tales compuestos y a métodos para su utilización como agentes terapéuticos.
Patent UY-28149-A1 (UY)
Title: Compuestos quimicos
Inventor: HERON NICOLA MURDOCH
IPC: C07D403/14
Filed: 2003-12-23
Abstract: Derivados de quinazolina de fórmula (I): donde A es un heteroarilo de 5 miembros que contiene un átomo de nitrógeno y uno o dos átomos de nitrógeno adicionales; composiciones que los contienen, procesos para su preparación y su uso en terapia.
Patent UY-29222-A1 (UY)
Title: Compuestos y derivados de dibencil amina
Inventor: CHANG GEORGE
IPC: A61K31/41
Filed: 2005-11-22
Abstract: Compuestos y derivados de dibencil amina, composiciones farmacéuticas que contienen dichos compuestos y el uso de dichos compuestos para elevar ciertos niveles de lípidos en plasma, incluyendo el colesterol de las lipoproteínas de alta densidad, y para reducir otros niveles de lípidos en plasma, tales como el colesterol de las LDL y los triglicéridos y, por consiguiente, tratar enfermedades exacerbadas por los niveles reducidos de colesterol de las HDL y/o niveles elevados de colesterol de las LDL y triglicérido, como la aterosclerosis y las enfermedades cardiovasculares en algunos mamíferos, incluyendo seres humanos.
Patent UY-31287-A1 (UY)
Title: Antagonistas del receptore de bradiquinina b1. sus procesos de preparación y aplicaciones.
Inventor: WALTER RAINER
IPC: A61K31/495
Filed: 2008-08-13
Abstract: Objeto de la presente invención son compuestos de la fórmula general I en la que A, B, D, Y, R1, R2, R3, R4 y R5 se definen como se mencionaron en la descripción, sus enantiómeros, diastereómeros, sus mezclas y sus sales, en especial sus sales fisiológicamente tolerables con ácidos o bases orgánicos o inorgánicos, que presentan valiosas propiedades, su preparación, los medicamentos que contienen los compuestos farmacológicamente eficaces, su preparación y su uso.
Patent ZW-14181-A1 (ZW)
Title: Method of and apparatus for assessing coins
Inventor: LEWIS CHRISTOPHER MICHAEL
IPC: G07D5/08
Filed: 1981-06-17
Abstract: The invention relates to a coin validator for use in a micro-processor controlled call coin box telephone instrument. The validator comprises first and second coil sets driven by square wave interrogation pulses. The arrangement of the coils is such that when a coin is in the coin-runway of the call coin box, one coil pair is used to interrogate the coin in the runway while the other coil pair provides environmental conditions apertaining to the runway. The information generated by both coil sets is combined thereby compensating for environmental changes and drift. Information pertaining to the relative response times of the secondary coils is then used to determine coin validity.
Patent CS-659286-A1 (CS)
Title: Combustion equipment
Inventor: BALJUK GRIGORIJ F
IPC: F23C5/32
Filed: 1986-09-15
Abstract: The unit has a lined cylindrical combustion chamber provided with an air jacket, connected to the combustion chamber cavity by nozzles situated in the lining and placed in pairs and diametrically opposite. A fuel supply pipe is placed along each nozzle axis. The economy is increased by improving the fuel combustion quality since the outlet sections of the adjacent nozzles are in tight contact with their side surfaces. USE - For burning natural gas to obtain high temp. combustion products. Bul. 42/15.11.87 (3pp Dwg.No.1/2)
Patent ES-173046-A1 (ES)
Title: Mejoras en la fabricacion de pilas para el alumbrado electrico de lampara para bicicletas
Filed: 1946-03-29
Abstract: Mejoras en la fabricación de pilas para el alumbrado eléctrico de lámparas para bicicletas caracterizadas por el empleo de un pila seca unida con un reflector estando la pila seca acondicionada de modo que quede destruida en el momento de ser separada del soporte del dispositivo de alumbrado sobre el marco de la bicicleta.
Patent ES-179179-A1 (ES)
Title: PERFECCIONAMIENTOS EN LOS MECANISMOS DE ALIMENTACIoN DE LAS PLUMAS ESTILOGRáFICAS
Filed: 1947-08-02
Abstract: Perfeccionamientos en los mecanismos de alimentación de las plumas estilográficas, caracterizado esencialmente, por el hecho de efectuar los movimientos sucesivos de expansión y contracción de la goma depósito de la tinta, mediante un mecanismo de giro continuado del remate del culote de la pluma, cuyo giro se transforma merced a un montaje original, en un movimiento axial de vaivén de una pieza intermedia que, obra directa o indirectamente sobre el muelle de lámina interior del cuerpo de la pluma, siendo el citado mecanismo, un sistema empujador circular de cruceta y un sistema receptor de aletas helicoidales dispuesto en un cuerpo prismático -pieza intermedia-, libre de trasladarse axialmente sin giro.
Patent ES-179489-A1 (ES)
Title: Mejoras en sistemas oscilantes modulados en frecuencia
IPC: H04Q1/442
Filed: 1947-08-28
Abstract: Mejoras en sistemas oscilantes modulados en frecuencias caracterizadas por un método de variación de frecuencia de un oscilador el cual comprende un suministro de energía a un circuito tanque para mantener en él oscilaciones, acoplamiento de un extremo de una línea larga de transmisión al referido circuito tanque,acoplamiento de una impedancia al otro extremo de la referida línea de acuerdo con las señales que deban ser transmitidas.
Patent ES-193227-A1 (ES)
Title: Perfeccionamientos en y aplicables a instrumentos para escribir
Filed: 1950-05-30
Abstract: Perfeccionamientos en y aplicables a instrumentos para escribir caracterizados por una extremidad de escritura para un instrumento de escritura de punta de bola comprendiendo un miembro de bas sobre el cual descansa la bola y un manguito que rodea la bola está formado con un asiento lateral para la bola y está montado para que pueda tener un movimiento deslizante o de corredera con relación al miembro de base mencionado.
Patent ES-196756-A1 (ES)
Title: PROCEDIMIENTO PARA LA PREPARACIoN DE TREO-P.-NITROFENIL-1-DICLOR-ACETILAMINO-2-CLORO-3-PROPANOLES-1 RACÉMICO Y oPTICAMENTE ACTIVOS
Filed: 1951-02-28
Abstract: Procedimiento para la preparación de treo-p nitrofenil-l-dicloracetilanlino-2-cloro-3-propanoles-l racémico y 6pticamente activos caracterizándose porque se efectúa la transformación de los treo-(racémicos d y l) - diclorometilo-2-(p~nitrofenilo)-hidroximetilo-4-oxazolinas-2 en treo-(racémicos-d o l) nitrofenilo-l-dicloracetilamino-2- cloro-3-propanoles-l atacando las oxazolinas por medio del ácido clorhidrico seco a temperatura ordinaria en un disolvente anhidro tal como el dioxano.
Patent ES-197123-A1 (ES)
Title: UN NUEVO EVAPORADOR PARA FRIGORiFICOS DE ABSORCIoN
Filed: 1951-03-24
Abstract: Nuevo evaporador para frigoríficos caracterizado por las disposiciones que se detallan a continuación. Tener el tubo de llegada del amoniaco líquido colocado en el interior del tubo de llegada del gas inerte y concéntricamente con el. Existir a lo largo del espacio entre ambos tubos numerosas placas circulares concéntricas con ellos cortadas en un segmento para dejar paso al gas y colocadas de trecho en trecho perpendicularmente al camino y de modo que el corte corresponda alternativamente en ambos extremos de un diámetro. Tener los platillos de cascada para evaporar el amoníaco en forma tronco-cónica con el ensanchamiento hacia abajo y con rebordes externos hacia arriba fuertemente apretados a la cara interna de la caja cilíndrica del evaporador y con la abertura. pequeña del tronco de cono metida a presión sobre la pared exterior del tubo de llegada del gas inerte. Ir colocados los sucesivos platillos de cascada de modo que sus perforaciones del fondo resulten en verticales distintas alternativamente para repartir circularmente la masa de evaporación. Terminar el tubo de llegada de amoníaco líquido en un ensanchamiento sobre el platillo superior para que el líquido caiga sobre éste de manera uniforme.
Patent ES-262361-A1 (ES)
Title: Subhalide distillation of aluminum
IPC: C22B21/00
Filed: 1960-11-11
Abstract: <PICT:0947227/C3/1> Thermally unstable gaseous compounds of aluminium, such as sub-halides, are decomposed by passage along a path defined by surfaces of graphite having an apparent specific gravity of greater than 1.5, the graphite being cooled at such a rate as to maintain its surface temperature between about 1200 DEG C. and 660 DEG C. Cooling may be effected by allowing heat to radiate from the graphite to a surrounding thermally conductive body spaced therefrom, said body being cooled if necessary by liquid coolant. Excessive cooling at the outlet end of the condenser may be avoided by interposing thermal shielding between the graphite and the outer body. In the form illustrated, the graphite forms a column of trays 44 and 45, each having a perforated bottom plate, the holes in alternate plates being offset, and the column is closed by cover 49, and by well 50. The entire graphite assembly is enclosed in steel shell 52, which may be cooled by coil 53.
Patent ES-263822-A1 (ES)
Title: Certain benzimidazoles carrying thiazolyl, thiadiazolyl and isothiazolyl substituents in the 2 position
IPC: C07D417/04
Filed: 1961-01-04
Abstract: The invention comprises (a) bases of the general formula: <FORM:0948635/C2/1> (wherein R represents a 5-membered heterocyclic radical containing nitrogen and sulphur, R1 represents a hydrogen atom or a C1-5 alkyl, a C2-5 alkenyl or a hydrocarbon carboxylic acyl radical, and each of R2 and R3 represents a hydrogen atom or a C1-5 alkyl or haloalkyl radical) and their acid addition salts (b) the preparation of the bases, except those in which R1=acyl, by reacting a compound RB (wherein B represents a carboxy, carbalkoxy, carboxamido, acyl halide or aldehyde radical) with a compound of the general formula: <FORM:0948635/C2/2> (wherein Y represents -NO2 or -NHR1 and R1 is not acyl), and, when B=CHO, oxidizing the intermediate, and, when Y=NO2, reducing the intermediate to form a final product in which R1=H (c) the preparation of the bases in which R1 is other than hydrogen by reacting an alkali metal salt of a compound in which R1=H with a C1-5 alkyl or C2-5 alkenyl ester of a strong acid or with an acylating agent and (d) veterinary compositions containing compounds (a) mixed with or dispersed in a non-toxic carrier or diluent. In process (b) when B=CHO the oxidation may be effected simultaneously with the condensation by working in a reaction medium comprising nitrobenzene, or a Schiff's base may be first formed and then oxidized with a heavy metal oxidizing agent to form a heavy metal salt of the benzimidazole from which the free benzimidazole is liberated by the addition of a reagent forming an insoluble compound with the heavy metal. When Y=NO2 and B=COO Alkyl or CO Halogen, an anilide is first formed and is then heated with a reducing system. The veterinary compositions, which have anthelmintic properties, may be in the form of an animal feed supplement, a dispersible wettable powder, a bolus or a liquid drench.
Patent ES-267732-A1 (ES)
Title: Gas tight seal and method of manufacture
IPC: H01J5/24
Filed: 1961-05-27
Abstract: A gas-tight envelope, e.g. for a cathode-ray tube or sealed beam headlamp, comprises two portions sealed together with a thermoplastic material comprising a fusible linear superpolyester of an aromatic dicarboxylic acid and a dihydric phenol having an intrinsic viscosity of at least 0.5 decilitres per gram, e.g. hydroquinone terephthalate isophthalate. The sealing compound may be pre-formed into a gasket by applying heat and pressure to the powdered compound, the gasket being placed between the envelope portions which are evacuated and heated to a temperature which is preferably above the melting-point of the compound. Alternatively, the sealing compound may be applied to one or both envelope portions as a solution, paint or slurry, or in finely-divided powdered form, the envelope portion(s) being heated to above the compounds melting-point. Either or both of the envelope portions may be of glass, metal or ceramic, and may have phosphor or reflective coatings thereon.
Patent ES-270609-A1 (ES)
Title: Permeability separatory apparatus, permeability separatory membrane element, method of making the same and process utilizing the same
IPC: A23F5/28
Filed: 1961-09-19
Abstract: <PICT:0970400/C1/1> A process for treating solutions, suspensions or slurries by osmosis, reverse osmosis or dialysis employs as semi-permeable membranes hollow fibres. As shown in Fig. 1, a cell 10 has inlet 11 and outlet 12, end plates 17 supporting the terminal portions of bundles 19 of fibres, and outlets 13 for the permeate. The fibres may incorporate ion-exchange constituents. Specific examples disclose the desalification of sea water, the concentration of aqueous solutions of sodium chloride, copper sulphate and ammonium nitrate, and the recovery of sodium hydroxide from viscose press liquor, using in all cases cellulose triacetate fibres. Numerous other uses are listed, and mention is made of water-softening and the treatment of sewage sludge.ALSO:Glycerine, glycols, lactic acid, glycine, sodium glutamate and alcohol solutions are concentrated and ethanol-isopropanol-water ternary azeotropes separated by passage through a cell containing as semi-permeable membranes hollow fibres.ALSO:A styrene-butadiene latex is concentrated by passage through a cell containing cellulose triacetate fibres, water being removed from the interior of said fibres.ALSO:Fruit and vegetable juices and beverages are concentrated by passage through a cell containing as semipermeable members a multiplicity of hollow fibres. Mention is made of orange, grapefruit, grape, apple, tomato, carrot, cabbage and celery juices, skimmed milk, and extracts of coffee and tea specific examples describe the concentration of apple cider, coffee solution and orange juice using cellulose triacetate fibres.
Patent ES-292101-A1 (ES)
Title: Improvements in or relating to stacking boxes or trays
IPC: B65D5/00
Filed: 1963-09-20
Abstract: The four walls of an open box formed by folding up the sides 2 of a cardboard blank are joined at the corners by a corner joint consisting of a bent strip 4 fitted into slots 3 cut in the box walls and a block 6 inserted into the space defined by a corner and its bent strip. For extra rigidity a clasp may be fitted on the outside of the corner and engaging with the bent strip. The strip 4 is placed in the slots 3 with the folded ends 5 bearing against the exterior of the walls. A solid block 6 forms the corner post and is inserted into the space formed by the two sides 2 and the strip 4. For increased rigidity the folded ends 5 may be engaged with a corner clasp 7 held against the outside walls of the corner and forming an integral part of the strip 4. The post 6 may be longer than the walls to provide a clearance when stacked. If the walls 2 are deep rigidity is improved by a second similarly shaped strip 4 and external clasp 7 fitted into two additional slots located in the lower half of the walls.
Patent ES-336533-A1 (ES)
Title: 5-nitrofurfural 3,5-dinitrosalicyloyl-hydrazone
IPC: C07D307/75
Filed: 1967-02-07
Abstract: The novel compound, 5-nitrofurfural 3,5-dinitrosalicyloylhydrazone is prepared by reacting 3,5-dinitrosalicylic acid hydrazide with 5-nitrofurfural or an acetal or acylal thereof containing 1 to 8 carbon atoms in the acetal or acylal moiety. The compound is useful for promoting the growth of poultry or fowl and/or controlling histomoniasis in poultry or fowl.
Patent ES-338188-A1 (ES)
Title: Solid composite boards having a compact core of adhesive binder and 85{14 98 percent by volume of porous, nonabsorbing granulates selected from the group consisting of cork bark, and vermiculite
IPC: E06B3/64
Filed: 1967-03-17
Abstract: A solid board, such as a door plate, comprising a solid core having a first and second core face and a frame surrounding said core adhesively connected thereto and having a first and second frame face flush with said first and second core face respectively. The first and second surface sheets are uniformly adhesively secured to the first core and frame face and to the second core and frame face respectively the core consists of a compact core mass-produced from porous nonabsorbing granulates, which have been brought mutually to adhere to each other by adhesive means. There are reinforcement means embedded in the core mass which consist of a number of strips made of fibrous material each having a width equal to the frame thickness and extending between the two surface sheets.
Patent ES-338549-A1 (ES)
Title: Improvements in and relating to Multilayer Circuit Structures
IPC: H05K3/46
Filed: 1967-03-28
Abstract: In a method of making a multilayer printed circuit board, circuit patterns 16, 18, 20, Fig. 2, are formed on a plurality of green ceramic sheets 10, 12, 14 with a paste comprising powdered metal or reducible metal compound in a volatile binder, through-holes 22, 24, 26 in said sheets also being filled with said paste the sheets are then stacked and fired to sinter the sheets together, Fig. 5, to convert any metal compound to the metal, and to cause the metal to form capillary paths 42 along said circuit pattern finally the said capillary paths are filled with molten conductor metal 52. A preferred ceramic for the sheets is zirconium alkaline earth porcelain (ZAEP) aluminas, beryllias, forsterites, steatites, and mullites may also be employed. Preferred metals include Mo, Mo-Mn, Zr, Fe, Cb, W, Ti, Ta, and mixtures thereof compounds of the said metals and oxides of Li-Mo may alternatively be used. The capillary paths may be either metallized tubes, as shown, or porous lattice-like structures they are filled by immersion in a bath of molten metal, e.g. Cu or Al, in a reduced pressure atmosphere alternatively, metal preforms are butted against the capillary ends and melted. A preferred composition of ZAEP is:- After milling for 8 hours the slurry is dried, pulverized, calcined, repulverized and micromilled, after which it is mixed with resin, solvents, and wetting and plasticizing agents in the following proportions:- In a first example, ZAEP green sheets are screen printed with a circuit pattern of paste comprising 40 gms powdered MoO 3 and 13À5 gms. medium containing betaterpenyl and ethyl cellulose. After stacking, the sheets are subjected to a burn-off in air at 400 C. followed by firing in dry H 2 at 1210 C. Capillaries are filled by immersion in a molten Cu bath at 1140 C. In another example, terephthalic acid is added to the paste, the sintering is carried out at 1285 C. in, a moist H 2 atmosphere, and the capillaries are filled in an Al bath at 700 C. Other examples using Mo-Mn powder to form the paste are described in the Specification.
Patent ES-339929-A1 (ES)
Title: Improvements in and relating to Mixing and Homogenising Apparatus
IPC: B01F5/00
Filed: 1967-04-28
Abstract: A mixing and homogenizing apparatus for viscous liquids up to the consistency of bread dough has a plurality of axially slotted coaxial interdigitating fixed and rotatable drums. As shown fixed drums 19, 20, 21 interdigitate with rotatable drums 22-25 material enters at 10 and passes outwardly through the slots in the drums to the outlet 11. The slots may be of smaller size and increased number as their distance from the axis increases, and are preferably of outwardly increasing trapezoidal crosssection (see Figs. 4 and 5, not shown). For the reduction of lumps there may be upstream of the drums a reducing device comprising chopping means 14, a perforated disc 15, and a cutter head 16 of the disc. There may also be a downstream resiliently loaded against the downstream face spring-loaded slotted disc assembly 26, 27.
Patent ES-347586-A1 (ES)
Title: Method of manufacturing tinplate
IPC: B23K20/04
Filed: 1967-11-24
Abstract: Tinplate is manufactured by electrolytically applying a coating of tin 3 to steel strip 4, mechanically compacting the interfaces of the two metals by cold-working the coated strip e.g. by passage between rolls 1 and subjecting the compacted strip to an elevated temperature lower than the melting point of tin, to increase the thickness of alloy 5, 5a formed at the steel/tin interface. The rise in temperature of the strip is in part provided by the working of the metal. A surface finish having desired optical properties may be imparted to the strip by the work elements during cold working. The strip may subsequently be subjected to chemical or passivation treatment, e.g. by passage through a heated, pressurized chamber Fig. 2 (not shown).