baber/WOPTO huggingface dataset:
Patent MX-2022009982-A (MX)
Title: Gene therapy for treating cdkl5 deficiency disorder.
Inventor: CRAIG STEWART
IPC: C12N15/86
Filed: 2021-02-11
Abstract: This present disclosure provides adeno-associated viral vectors, recombinant adeno-associated virus (rAAV), and methods of their use in gene therapy for treating CDKL5 deficiency disorder (CDD). Also provided are pharmaceutical compositions comprising an rAAV of the invention and a pharmaceutically acceptable carrier or excipient. These pharmaceutical compositions may be useful in gene therapy for the treatment of CDD caused by mutations in CDKL.
Patent MX-2022010286-A (MX)
Title: Programmable shells for virus encapsulation.
Inventor: DIETZ HENDRIK
IPC: C12Q1/68
Filed: 2021-02-22
Abstract: The present invention relates to a macromolecule-based nanostructure, such as a DNA-based nanostructure, for encapsulating a virus or viral particle, to a composition comprising a virus or viral particle encapsulated by such a macromolecule-based nanostructure according to the present invention, and to a method for encapsulating a virus or viral particle by using such a macromolecule- based nanostructure.
Patent MX-2022014255-A (MX)
Title: Compositions useful for treatment of pompe disease.
Inventor: GOTSCHALL RUSSELL
IPC: A61K38/46
Filed: 2021-05-14
Abstract: Provided herein is a method for reducing the progression of abnormal muscle pathology and/or reversing abnormal muscle pathology in a patient, wherein the patient has been diagnosed with Pompe disease or is suspected of having Pompe disease. The method comprising administering to the patient a recombinant AAV (rAAV) having an AAV capsid and a vector genome packaged therein, wherein the vector genome comprises: (a) a 5' inverted terminal repeat (ITR); (b) a promoter; (c) a nucleotide sequence encoding a chimeric fusion protein comprising a signal peptide and a vIGF2 peptide fused to a human acid-a-glucosidase (hGAA), (d) a poly A; and (e) a 3' ITR. Also provided are pharmaceutical composition comprising an rAAV described herein for use in treating a patient having or suspected of having Pompe disease.
Patent MX-GT06000017-A (MX)
Title: Process for producing continuous pieces of expanded polystirene foam.
Inventor: AGUILERA LUZ ANTONIO
IPC: B29C65/00
Filed: 2006-08-30
Abstract: Provided is a novel industrial process for manufacturing pieces of polystyrene foam (EPS) having an arbitrary length and a constant transversal section, also comprising density mixtures located by zones according to the mechanical and thermal properties required for each application thereof. A machine (device) is also included for manufacturing the solid pieces comprising density mixtures and a product made of polystyrene foam (EPS) having an arbitrary length and a transversal section presenting a constant geometry, comprising density mixtures located by zones, which are defined by the mechanical and thermal properties required by the application thereof. The manufacture of said products is carried out by attaching partially pre-cooked segments having the same or different densities, both in longitudinal and transversal directions. The present invention may reduce the traditional process down to three steps, thus generating savings in the manufacturing process, allowing variants not i ncluded in the traditional process to be manufactured, thereby widening the application range of said type of products.
Patent MX-PA00006934-A (MX)
Title: Use of hemoglobin derivatives for determining plasma and/or blood volume.
Inventor: KLAUS SOMMERMEYER
IPC: G01N33/72
Filed: 2000-07-14
Abstract: The invention concerns the use of hemoglobin derivatives for determining plasma and/or blood volume, wherein the hemoglobin derivatives are stable chromoproteins with a molecular weight of at least 64 kDa. The use crin encompass the treatment of a patient wherein (a) a defined quantity of hemoglobin derivative is applied to a patient, (b) the mixing of hemoglobin derivative with the blood of the patient is awaited, (b) at least one sample is taken from the patient, (c) the content of the hemoglobin derivative and/or the content of. the hemoglobin derivative bound ligand in the sample is determined and (d) the plasma and/or blood volume ascertained therefrom. The invention also concerns preparations for determining plasma and/or blood volume which contain hemoglobin derivatives and are characterized in that the hemoglobin derivatives are stable chromoproteins with a molecular weight of at least 64 kDa which carry at least in part carbon monoxide as ligand, as well as processes for thei r manufacture.
Patent MX-PA01010859-A (MX)
Title: Metabolic intervention with glp-1 to improve the function of ischemic and reperfused tissue.
Inventor: COOLIDGE THOMAS R
IPC: A61K47/04
Filed: 2000-04-27
Abstract: Individuals in need of treatment of ischemia-related reperfusion are treated, preferably intravenously, with a composition which includes a compound which binds to a receptor for the glucagon-like peptide-1. The invention relates to both the method and compositions for such treatment.
Patent MX-PA01011001-A (MX)
Title: Novel quinones as disease therapies.
Inventor: FRYDMAN BENJAMIN
IPC: C07D235/18
Filed: 2000-04-27
Abstract: Novel quinones are provided, as well as compositions comprising these novel quinones. Methods of using the novel quinones in treatment of various indications including cancer are also provided.
Patent MX-PA01012195-A (MX)
Title: Acrylic modified waterborne alkyd or uralkyd dispersions.
Inventor: CLARK MARK D
IPC: C08F273/00
Filed: 2000-05-26
Abstract: A water-based latex of an acrylic-modified waterborne alkyd or uralkyd dispersion inwater is described. The acrylic-modified waterborne alkyd or uralkyd is a hybrid resin prepared by the polymerization of at least one latent oxidatively-functional (LOF) acrylic monomer in the presence of a waterborne alkyd or uralkyd. Alternatively, the acrylic-modified waterborne alkyd or uralkyd is a hybrid resin prepared by shearing a mini-emulsion based on a solvent-borne alkyd or uralkyd dissolved in at least one LOF acrylic monomer. Preparation of the latexes may be achieved by emulsion polymerization of at least one latent oxidatively-functional acrylic monomer in the presence of a waterborne alkyd or uralkyd whereby the latent oxidative functionality of the acrylic polymer survives polymerization. Water-based latexes may also be prepared by polymerizing a sheared mini-emulsion based on a solvent-borne alkyd or uralkyd dissolved in at least one LOF acrylic monomer such that the latent oxidative functionality of the acrylic polymer survives polymerization. Such acrylic-modified waterborne alkyd or uralkyds are useful in a variety of coating compositions.
Patent MX-PA02005175-A (MX)
Title: Vitamin d analogues.
Inventor: JEAN-MICHEL BERNARDON
IPC: C07D333/56
Filed: 2000-11-22
Abstract: The invention concerns novel tri-aromatic compounds of general formula (I) and the method for preparing them, and their use in pharmaceutical compositions for use in human or veterinary medicine (in dermatology, cancerology, as well as in the fields of autoimmune diseases and of organ or tissue transplants in particular), or in cosmetic compositions.
Patent MX-PA02007341-A (MX)
Title: Tubular structural reinforcing member with thermally expansible foaming material.
Inventor: HOPTON GREGORY W
IPC: B62D29/00
Filed: 2001-01-22
Abstract: A reinforcing member (10) for receiving thereon a thermally expansible reinforcing material (22) includes a tubular carrier (20) and a fastener (26) mechanically affixing the reinforcing material to the carrier. The tubular carrier preferably has a continuous arcuate wall with the reinforcing material received on the exterior thereof. The reinforcing material may be provided as a plurality of longitudinally spaced annular elements, an elongated sleeve, or a prism shaped element. Upon heating, the reinforcing material expands and bonds the carrier to the structure member to provide additional strength and stiffness.
Patent MX-PA02009422-A (MX)
Title: Voicemail for wireless systems.
Inventor: SNELGROVE WILLIAM MARTIN
IPC: H04M3/42
Filed: 2001-03-21
Abstract: The present invention provides a novel system, method and apparatus for managing voicemails over a wireless local loop. The system provides for the placement of a voicemail client local to the subscriber and a voicemail server at the base station. The voicemail server and voicemail client cooperate with the base station to determine appropriate times to transfer voicemails over the WLL and thereby free up bandwidth on the WLL for higher priority traffic, such as voice calls. Another embodiment of the invention provides a method for receiving voicemails utilizing the system. Yet another embodiment provides a method for delivery of voicemails from a caller to destination subscriber. Various prioritization criteria can be used to provided desired utilization of bandwidth.
Patent MX-PA03002733-A (MX)
Title: Method and device for producing singulet oxygen.
Inventor: KLEMM JORG
IPC: C01B13/02
Filed: 2001-09-28
Abstract: The invention relates to a device for producing singulet oxygen, comprising a housing (1) forming a chamber which has at least two opposite surfaces. One (4) of said surfaces is transparent and the other is covered by a coating made from a dye excited by light, and a light source (3) for radiating the surface (6) coated with the dye. The surface (6) coated with the dye is formed by a substrate comprising a finely roughened surface. The dye is introduced in the indentations of the finely roughened surface by polishing. The light source can be formed by luminous diodes (3), whose light emission comprises a wavelength located within the range of maximum radiation absorption of the dye of the coated surface (6).
Patent MX-PA03003403-A (MX)
Title: Method and apparatus for canceling pilot interference in a cdma communication system.
Inventor: JOU YU-CHEUN
IPC: H04B1/707
Filed: 2001-10-16
Abstract: Techniques for canceling pilot interference in a wireless (e.g., CDMA) communication system. A received signal typically includes a number of signal instances (i.e., multipaths). For each multipath desired to be processed, the other multipaths act as interference on the desired multipath. If the pilot is generated based on a known data pattern (e.g., all zeros) and covered with a known channelization code (e.g., a Walsh code of zero), then the pilot in an interfering multipath may be estimated as the spreading sequence at a time offset corresponding to the arrival time of that multipath. The pilot interference from each interference multipath may be estimated based on the spreading sequence for the interfering multipath and the despreading sequence for the desired multipath. The total pilot interference from a number of interfering multipaths may be subtracted from the data component in the desired multipath to provide pilot-canceled data having improved performance.
Patent MX-PA03008783-A (MX)
Title: Mixtures of fructose and lactose as a low-calorie bulk sweetener with reduced glycemic index.
Inventor: WARREN L ZEHNER
IPC: A23L27/00
Filed: 2002-03-22
Abstract: Mixtures of fructose and lactose are useful for reducing caloric intake and glycemic index for individuals who are overweight, glucose-impaired, diabetic, or who just consume too large a fraction of their calories from added sugars. The fructose/lactose sweetener is included in the daily diet as a one-for-one replacement for added sugars in various edible formulations without sacrificing quality of taste. Sucrose can be used as a replacement for all or part of the fructose in the claimed sweetener to increase sweetness or improve certain functional properties without substantially changing caloric value. The claimed mixtures of fully-caloric sugars work synergistically to reduce available calories and blood sugar concentration. Specifically, fructose interferes strongly with normal small-intestinal absorption of lactose and interferes moderately with sucrose absorption, while lactose interferes with normal small-intestinal absorption of both sucrose and starch. Unabsorbed di- and oligosaccharides pass into the colon and cause increased growth of healthful bacteria, making the new sweetener useful as a prebiotic. No gastrointestinal symptoms of sugar intolerance were observed when the claimed sugar mixtures were ingested at normal dietary levels.
Patent MX-PA04000420-A (MX)
Title: Flameproof textile surface structures.
Inventor: HANS-DIETER EICHHORN
IPC: A41D31/00
Filed: 2002-07-05
Abstract: The invention relates to textile surface structures containing A) 20 to 90 wt % melamine fibres A), and B) 10 to 80 wt % flameproof polyester fibres B).
Patent MX-PA04001077-A (MX)
Title: Methods for detecting and polling downstream modems.
Inventor: ROBERT P BASIL
IPC: H04B7/212
Filed: 2002-07-26
Abstract: Methods are provided for finding the address of a previously undiscovered client modem by first detecting the presence of a previously undiscovered client modem on a shared communication media and then discerning the address for the newly discovered client modem. The methods can be coupled with group polling to eliminate the time wasted polling (104, 112, 120) a modem without data to transmit. In one implementation of group polling, a broadcast message (204) is sent to all modems (or a selected subset of modems). Each modem requiring service responds with a short burst of energy (216) in its predefined time slot. These time slot responses (208) are recorded and then normal poll messages are sent out to only the modems requesting service. A timeslot can be allocated for responses (212) from undiscovered modems.
Patent MX-PA04001475-A (MX)
Title: Enhancing solubility of iron amino acid chelates and iron proteinates.
Inventor: CLAYTON ERICSON
IPC: C07C231/22
Filed: 2002-08-15
Abstract: A method of enhancing the solubility of iron amino acid chelates and iron proteinates is disclosed. This is accomplished by mixing an effective amount of an organic acid solubilizing agent into existing iron amino acid chelates or iron proteinates. The iron amino acid chelates and iron proteinates may have a ligand to metal molar ratio from about 1:1 to 4:1, preferably 2:1 to 3:1.
Patent MX-PA04005651-A (MX)
Title: Antenna element, feed probe; dielectric spacer, antenna and method of communicating with a plurality of devices.
Inventor: CHING-SHUN YANG
IPC: H01Q21/28
Filed: 2004-06-11
Abstract: A multiband base station antenna for communicating with a plurality of terrestrial mobile devices is described. The antenna including one or modules, each module including a low frequency ring element; and a high frequency dipole element superposed with the low frequency ring element. The element includes a ground plane; and a feed probe directed away from the ground plane and having a coupling part positioned proximate to the ring to enable the feed probe to electromagnetically couple with the ring. A dielectric clip provides a spacer between the feed probe and the ring, and also connects the ring to the ground plane. An antenna element is also described including a ring, and one or more feed probes extending from the ring, wherein the ring and feed probe(s) are formed from a unitary piece.
Patent MX-PA04007510-A (MX)
Title: Tolerogenic peptides from myelin basic protein.
Inventor: MAZZA GRAZIELLA
IPC: A61P25/00
Filed: 2003-01-30
Abstract: There is provided a peptide which is capable of binding to an MHC class I or II molecule without further processing (i.e. an apitope) which comprises a portion of the region (131-158) of myelin basic protein, in particular there is provided an apitope which is selected from the following myelin basic protein peptides: (134-148, 135-149, 136-150, 137-151, 138-152, 139-153, 140-154). There is also provided the use of such a peptide in a pharmaceutical composition and a method to treat and/or prevent a disease using such a peptide.
Patent MX-PA04011068-A (MX)
Title: Fluid transport assemblies with flame retardant properties.
Inventor: ZHIMING ZHOU
IPC: B32B7/022
Filed: 2003-03-25
Abstract: The invention provides an assembly for the control and removal of fluids, the assembly comprising: A fluid control layer having a top side and a bottom side, the top side constructed to facilitate the evaporation or the flow of a fluid disposed thereon; a fire retardant material having a first major surface and a second major surface, the first major surface associated with the bottom side of the fluid control layer, the fire retardant material comprising a polymer; and an adhesive layer associated with the second major surface of the fire retardant material. A fluid management system for aircraft and a method for the use of the system in aircraft are also described.
Patent MX-PA04011688-A (MX)
Title: A port, a container and a method for accessing a port.
Inventor: SILVANO SFORACCHI
IPC: A61J1/05
Filed: 2003-05-28
Abstract: A port, a container and a method for accessing a port for injecting or withdrawing a liquid from the container are provided. The port may allow for the administration of, for example, a drug, to a patient and may be located on the container. The port has a septum having a target area. The port also has a support ring in contact with the septum. A cap is provided to protect the septum. The cap has a ring handle and allows for removal and exposure of the target area of the septum. A needle, for example, may be used to penetrate the septum allowing the addition or withdrawal of a liquid or other drug to or from the container.
Patent MX-PA05001989-A (MX)
Title: Extruded cleansing product.
Inventor: STAVINOHA EMIL SR
IPC: A61Q19/10
Filed: 2003-08-08
Abstract: The present invention is directed to a personal cleansing product which can be sized as a single use personal cleansing product. The cleansing product is an extruded foam product which can disintegrate upon contact with water when used in the standard fashion to wash. As the foam disintegrates, the cleansing agent held in the foam matrix is released. The disintegration of the product can take place slowly, over a period of time such that when an individually sized cleanser is used to scrub until it completely disintegrates, scrubbing duration is long enough to ensure desired levels of cleanliness have been attained. Alternatively, the product can disintegrate immediately, and release all of the soap at essentially one time. The product is an extruded foam expanded from a mixture of a natural starch, a nucleating agent, a water soluble disintegrant, a blowing agent, a water soluble polymer, and a soap base. Optionally, the foam can include a destructured starch, natural, dyes, fragrances, and the like to obtain specific product characteristics.
Patent MX-PA05004636-A (MX)
Title: Method for correcting seismic data for receiver movement during data acquisition.
Inventor: DEWAYNE KINKEAD JACK
IPC: G01V1/38
Filed: 2005-04-29
Abstract: A method is disclosed for processing seismic data. The method includes determining a position of a seismic energy source and seismic receivers at a time of actuation of the source. A velocity of the seismic receivers with respect to the source position is determined at the time of actuation. An offset of the receivers is corrected using the velocity. A moveout correction is determined for the signals detected by the sensors based on the corrected offset and a velocity of earth media through which seismic energy passed from the source to the sensors.
Patent MX-PA05005509-A (MX)
Title: Body conforming undergarment.
Inventor: MONICA S DIAZ
IPC: A61F13/15
Filed: 2003-06-09
Abstract: An undergarment includes a body panel and a crotch member. The crotch member includes first and second terminal edges and laterally opposed side edges. The crotch member has a longitudinally extending length defined between the first and second terminal edges. The crotch member is connected to the body panel at an attachmentlocation, which is longitudinally spaced along the length of the crotch member from the first terminal edge thereof. The crotch member includes an unattached end portion that extends between the attachment location and the first terminal edge and that is unattached to the body panel. Methods of using and manufacturing the undergarment are also provided.
Patent MX-PA05007119-A (MX)
Title: Water circulation systems for ponds, lakes, and other bodies of water.
Inventor: JOEL J BLETH
IPC: C02F7/00
Filed: 2003-12-30
Abstract: Circulation systems for ponds, lakes, or other bodies of water. In one set of embodiments (1), water is drawn up from the depths of the body (4) for exposure to the atmosphere and to generate an overall, high flow circulation pattern throughout the entire body (4). In other embodiments (1'), the circulation in the body of water (4') is primarily limited to an upper aerobic zone (20) with only small and controlled volumes from a lower anaerobic zone (22) being brought up. Each system preferably includes a flotation platform (3), dish (19), impeller (21), and draft tube (5, 5') with specific modifications to the various systems to adapt them for use in a variety of environments.
Patent MX-PA05007197-A (MX)
Title: Hydraulically damping rubber bush bearing for vertical mounting.
Inventor: KRAMER KLAUS
IPC: F16F13/14
Filed: 2004-03-30
Abstract: The invention relates to a hydraulically damping rubber bush bearing. According to the invention, said bush bearing is configured in such a way that it can be mounted vertically in order to receive cardanic forces and it also has simple geometry and a simple structure. The inventive bearing consists of chambers which receive the damping means and which comprise at least one undercut in the direction of the bearing axis in the region of the axial ends thereof. Also, the inner cage and the elastomer bearing body are axially shortened in the corresponding peripheral section thereof in relation to the other peripheral sections.
Patent MX-PA05010308-A (MX)
Title: Carton with dispenser.
Inventor: JOHN M HOLLEY JR
IPC: B65D71/00
Filed: 2004-03-19
Abstract: A package comprises an article group formed of at least two vertically arranged tiers of cylindrical articles (C) disposed on their sides in a side-by-side parallel fashion, and a carton disposed around the group. The carton comprises a top wall (16), opposed side walls (14, 18), an end wall (30b, 32b) and an article dispenser (D). The side walls (14, 18) are disposed alongside the ends of the articles of the group while the end wall (30b, 32b) is disposed adjacent to the side walls of the adjacent endmost articles. The dispenser (D) includes a corner portion of the carton formed from and detachably connected to the top, side and end walls to be removed from the carton to thereby define an opening for exposing at least some of the articles for removal. The opening is shaped to define a recess (83) in each side wall to reveal at least a part of the endmost article in the lowermost tier of the article group.
Patent MX-PA05010969-A (MX)
Title: Dyeing composition comprising at least one disulphide dye and method of dyeing human keratin fibers using this dye.
Inventor: GENAIN GILLES
IPC: A61Q5/10
Filed: 2005-10-12
Abstract: Disclosed herein is a dyeing composition comprising a particular disulphide dye and a method of dyeing human keratin fibers, such as hair, using this composition. This composition makes it possible to obtain particularly fast chromatic colorations.
Patent MX-PA05012754-A (MX)
Title: Live attenuated viral vaccines for eastern equine encephalitis virus.
Inventor: PARKER MICHAEL D
IPC: A61K39/395
Filed: 2004-05-26
Abstract: Live attenuated Eastern Equine Encephalitis (EEE) vaccines that outperform the PE-6 vaccine in mice aerosol challenged with > 1,000x LD50. Candidates include four furin --cleavage deletion mutants and one E3 deletion mutant. Each vaccine provided protection in birds against antigenically distinct North and South American strains of EEE. The PE-6 vaccine does not provide protection against South American EEEs. Animals inoculated with each of the vaccines of the invention developed neutralizing antibodies to EEE.