baber/WOPTO huggingface dataset:
Patent WO-2021217000-A1 (WO)
Inventor: STRABLEY CHRIS
IPC: B60C13/00
Filed: 2021-04-23
Abstract: A tire (10) and wheel assembly (12) including a rim (16) and a bead- lock (38, 40) on each side of the tire/wheel. The tire (10) defines a cross-sectional shape and include first and second bead cores (42, 44) which are coupled to the wheel assembly (12) via the rim (16) and the bead-lock (38, 40). The tire (10) includes a carcass layer (60) extending laterally between the first and second bead cores (42, 44).The carcass layer (60) includes first and second turnups (62, 64) extending around the first and second bead cores (42, 44). The tire (10) further includes a material beam layer (74) extending laterally between the first and second bead cores (42, 44) and radially exterior relative to the carcass layer (60). The tire (10) also includes a sidewall stiffening layer (82) extending laterally at least substantially from the first to the second bead core (42, 44). The carcass layer (60), the material beam layer (74), and/or the sidewall stiffening layer (82) are configured such that the cross-sectional shape or the radial height of the tire (10) remains substantially constant when supporting a load.
Patent WO-2021222043-A1 (WO)
Inventor: DEMAN EELCO
IPC: F16F1/373
Filed: 2021-04-24
Abstract: A dispensing pump (1000) includes a polymer compression spring (1048), base vents (1060) and a flow baffle (1092). The dispensing pump includes a pump base (1002), and a dispensing head (1004) having a piston stem (1034). The polymer compression spring assembly includes a slotted tubular spring element (1048) and first and second loading cones received at opposing ends of the slotted tubular spring element. The venting ports allow air to escape when capping the container after filling and the flow baffle reduces or prevents the product from being pulled into the pump accumulator before residual air (headspace) has been evacuated from the container during the initial priming strokes.
Patent WO-2021231136-A1 (WO)
Title: Product location system
Inventor: SOLOMON STANLEY B
IPC: H04W4/029
Filed: 2021-05-04
Abstract: The product location system process includes steps for forming an ad hoc peer-to-peer communication network by way of multiple connected devices communicating with one another, each of which include a communication circuit for sending and receiving data communications. Location information for each of the connected devices within the ad hoc peer-to-peer communication network may then be ascertained based at least in part on bi-lateral exchange of data communications among the multiple connected devices within the ad hoc peer-to-peer communication network. That location information may then be relayed by one or more of the connected devices to an external network for storage in a database, and the location information in that database may then be accessed in real-time from, e.g., by a Smartphone.
Patent WO-2021257213-A1 (WO)
Title: Predictive model application for file upload blocking determinations
Inventor: KARIN OMER
IPC: G06F21/55
Filed: 2021-05-13
Abstract: According to examples, an apparatus may include a memory on which is stored machine-readable instructions that may cause a processor to receive a request to upload a file to a directory and determine whether the request is a request to upload a predefined type of file to the directory. In addition, based on a determination that the request is a request to upload the predefined type of file to the directory, the processor may determine, through application of a predictive model, whether the directory is a user content directory and based on a determination that the application of the predictive model indicates that the directory is a user content directory, block the request and/or output a notification regarding the receipt of the request.
Patent WO-2021236570-A1 (WO)
Title: Pharmaceutical formulation containing remdesivir and its active metabolites for dry powder inhalation
Inventor: HUSSAIN ABID
IPC: A61K9/14
Filed: 2021-05-18
Abstract: The invention provides a pharmaceutical composition for dry powder inhalation and a preparation method thereof, wherein the composition comprises, a carrier material, preferably lactose and micronized remdesivir and/or its active metabolites (such as Alanine metabolite (Ala- met), Nucleoside monophosphate, and Nucleoside Triphosphate (NTP)) and/or its analog GS- 441524 and pharmaceutically acceptable salts thereof. The active pharmaceutical ingredient may be an anti-viral, taken as remdesivir and/or its active metabolites (such as Alanine metabolite (Ala- met), Nucleoside monophosphate, and Nucleoside Triphosphate (NTP)) and/or its analog GS- 441524. The dry powder inhalation containing Remdesivir and/or its active metabolites and/or its analog GS-441524 as active ingredients, further consisting of a breath-powered, dry powder inhaler, and a cartridge for delivering a dry powder formulation deep into the lungs for the treatment of respiratory disorders. The inhaler and cartridge can be provided with a drug delivery formulation comprising, for example, an active ingredient, including, small organic molecules, including, remdesivir and/or its active metabolites (such as Alanine metabolite (Ala-met), Nucleoside monophosphate, and Nucleoside Triphosphate (NTP)) and/or its analog GS-441524 and pharmaceutically acceptable salts thereof for the treatment of disease and disorders, for example, COVID-19 and other viral respiratory infections.
Patent WO-2021237209-A1 (WO)
Title: Metal-organic frameworks deliver small molecules and biomacromolecules for cancer immunotherapy
Inventor: LIN WENBIN
IPC: A61K45/00
Filed: 2021-05-24
Abstract: Modified metal-organic framework (MOFs) are described that have surfaces with enhanced ability to coordinatively bond to or electrostatically interact with therapeutic agents, such as nucleic acids and small molecules and proteins with phosphate or carboxylate groups. Methods of providing the modified MOFs are described that include replacing strongly coordinating metal oxo cluster capping groups with weakly coordinating capping groups and/or incorporating organic bridging ligands with electron-withdrawing groups. MOFs with surface attached therapeutic agents (e.g., immunotherapeutic agents) prepared from the modified MOFs are also described, along with methods of using the MOFs as to treat cancer, e.g., via radiotherapy-radiodynamic therapy (RT-RDT), either with or without the co-administration of another therapeutic agent, such as a chemotherapeutic agent or an immunomodulator. Thus, the described methods can involve cancer immunotherapy and  in situ  cancer vaccination.
Patent WO-2021248066-A1 (WO)
Inventor: SMITH JENNIFER JOY
IPC: C12Q1/68
Filed: 2021-06-04
Abstract: The present disclosure provides methods and diagnostic tools comprising classifiers and indicator cells that respond differentially to a sample derived from a subject having a disease or cancer, such as lung cancer, as compared to a control or normal sample. Also disclosed herein are methods of detecting a multicomponent gene expression readout from a genetically identical population of cells.
Patent WO-2021257815-A1 (WO)
Title: Digital assembly of spherical hydrogel voxels to form 3d lattice structures
Inventor: Cai Liheng
IPC: B29C64/10
Filed: 2021-06-17
Abstract: Systems and methods for 3D bioprinting of hydrogel voxels enable microfluidics-assisted digital assembly of spherical particles (DASP). The systems include a 3D motion system, a microfluidic printhead coupled to the 3D motion system, an extrusion device fluidly coupled to the microfluidic printhead, and a sacrificial support matrix. The sacrificial support matrix is designed to support the hydrogel voxels during printing and cross-link the hydrogel voxels. The system includes bio-inks comprising hydrogel compositions having independently controllable viscoelasticity and mesh size. The bio-inks are extruded by the extrusion device and microfluidic printhead to produce the hydrogel voxels. Exploiting the microfluidic printhead enables printing individual spherical hydrogel voxels with diameters from 150 micrometers (µm) to 1200 μm. Positioning and interconnection of the hydrogel voxels can be precisely controlled. The systems and methods produce free-standing 3D structures and can be used for producing functional tissue mimics.
Patent WO-2022005987-A1 (WO)
Title: Threaded tubular end protector
Inventor: TWEEDY NEIL E
IPC: B65D59/00
Filed: 2021-06-28
Abstract: A thread protector that has an external sleeve having threads disposed on an inner side to engage with pin threads disposed on a pin end of a tubular member. The thread protector also has a flange disposed on a first end of the external sleeve to engage with the pin end of the tubular member, the threads on the inner side of the external sleeve are disposed axially adjacent to the flange and radially adjacent to the end of the pin end of the tubular member. A method of protecting the pin threads of the pin ends of the tubular members. The method includes screwing the thread protector on the pin threads of the pin end of the tubular member.
Patent WO-2022010690-A1 (WO)
Title: Substrate apparatus and methods
Inventor: CAVALLARO III NICHOLAS DOMINIC
IPC: B65B25/14
Filed: 2021-06-29
Abstract: Substrate support apparatus can comprise a monitoring device configured to monitor a position of a suction device of a plurality of suction devices. In some embodiments, substrate packaging apparatus for packaging a leaning stack of substrates can comprise a substrate support structure and a compacting device. In some embodiments, methods can comprise stacking a plurality of substrates to form a leaning stack of substrates, imaging a feature of the leaning stack of substrates, and determining a characteristic of the leaning stack of substrates using information obtained during the imaging. In some embodiments, methods can comprise stacking an additional substrate on a leaning stack of substrates and determining a characteristic of the leaning stack of substrates with the substrate support apparatus while the substrate support apparatus engages the additional substrate.
Patent WO-2022026137-A1 (WO)
Inventor: QUIRK STEPHEN
IPC: A61F13/15
Filed: 2021-07-07
Abstract: An auto-biodegradable absorbent article formed at least in part from a biodegradable polymer is provided that includes an inactivated microorganism product. The absorbent article contains one or more microorganisms that are designed to secrete an enzyme that degrades the biopolymer, which can be a polyhydroxybutyrate polymer. The microorganism can naturally secrete the enzyme or can be genetically modified to secrete the enzyme. The microorganisms or bacteria incorporated into the absorbent article are particularly selected based upon their salt tolerance and enzyme production at certain salt concentrations.
Patent WO-2022046421-A1 (WO)
Inventor: JANKA MESFIN
IPC: C07C47/02
Filed: 2021-08-12
Abstract: Processes are disclosed for preparing at least one aldehyde under hydroformylation temperature and pressure conditions, comprising contacting at least one olefin with hydrogen and carbon monoxide in the presence of at least one hydrocarbon solvent or fluorinated solvent and a transition metal-based catalyst composition comprising a phospholane- phosphite ligand.
Patent WO-2022046752-A1 (WO)
Inventor: BLASI ROBERT
IPC: B25B27/073
Filed: 2021-08-24
Abstract: A tool for driving a shaft within an apertured member, the tool incorporating a segmented sleeve having upper, lower, and medial segments, each segment having upper and lower ends, a hollow bore of the lower segment being helically threaded; a shaft biasing screw mounted within the lower segment's hollow bore; upper and lower joints, the upper joint connecting the upper end of the screw with the upper segment, and the lower joint connecting the medial segment with the lower segment; a first gear component attached to the upper segment: a support frame attached to the medial segment; a second gear component mounted rotatably upon the support frame, the second gear component being positioned for rotating the first gear component; a rotary power input stem fixedly attached to the second gear component; and a clamp or hook arms adapted for positioning the apertured member beneath the screw's shaft biasing lower end.
Patent WO-2022051249-A1 (WO)
Title: Cartridges and related systems and methods
Inventor: BARNARD STEVEN
IPC: B01L3/00
Filed: 2021-08-31
Abstract: Cartridges and related systems and methods are disclosed. In accordance with an implementation, a method includes securing a sample container in a sample container receptacle of a cartridge using a sample container lock and coupling the cartridge to a cartridge receptacle of a system. The method also includes depositing a sample from the sample container within a sample well of the cartridge and determining a presence of a target molecule within the sample using the system. In response to the target molecule being present within the sample, the method includes releasing the sample container lock of the cartridge to allow the sample container to be removed from the sample container receptacle and for the cartridge to remain coupled to the system.
Patent WO-2022051443-A1 (WO)
Title: Preparation of nucleated rbc (nrbc) analogs for use as reference hematology controls in automated hematology analyzers
Inventor: LEE BEENA
IPC: G01N33/48
Filed: 2021-09-02
Abstract: The subject invention pertains to compositions of novel analogs of red blood cells that are distinguishable from white blood cells in a hematological instrument and processes for manufacturing such analogs. The processes for creating the compositions comprise washing, shrinking, and fixing cells at temperatures at or below room temperature.
Patent WO-2022056064-A1 (WO)
Inventor: ZHANG MICHAEL LONGQUIANG
IPC: A63F13/577
Filed: 2021-09-09
Abstract: Systems, methods, and media are provided for improved targeting of an individual object among a plurality of objects in a mutli-player online video game. The video game may include plurality of objects located at various places at a given frame. At each frame, a position of the objects is identified. If a player object (except for the player object associated with the user) is within a predetermined radius of another player object, a target position of the player object is modified relative to other player objects. Next, the target position of the player object is modified towards its original position within the frame. This process is repeated for each player object until the corresponding player object is no longer within the predetermined radius of another player object or a violation of a constraints prevents the modification from being performed.
Patent WO-2023048708-A1 (WO)
Title: System, method, and computer program product for identifying weak points in a predictive model
Inventor: WANG LIANG
IPC: G06F7/00
Filed: 2021-09-22
Abstract: Systems, methods, and computer program products that obtain a plurality of features associated with a plurality of samples and a plurality of labels for the plurality of samples; generate a plurality of first predictions for the plurality of samples with a first machine learning model; generate a plurality of second predictions for the plurality of samples with a second machine learning model; generate, based on the plurality of first predictions, the plurality of second predictions, the plurality of labels, and a plurality of groups of samples of the plurality of samples; determine, based on the plurality of groups of samples, a first success rate associated with the first machine learning model and a second success rate associated with the second machine learning model; and identify, based on the first success rate and the second success rate, a weak point in the machine learning first model or the second model.
Patent WO-2022066762-A1 (WO)
Inventor: AFEWERKI SAMSON
IPC: A61K31/785
Filed: 2021-09-22
Abstract: The invention relates to the film-forming antimicrobial, antibacterial, antiviral, antiparasitic, and antifungal composition comprises a) a film-forming materials, b) one or more antimicrobial, antibacterial, antiviral, antiparasitic, and antifungal compound(s), c) one or more solubilizing agents, and optionally, d) one or more plasticizer, and e), one or more surfactants or detergents. The invention also relates to a use in prevention or treatment of a disorder in a mammal, such as a human and use of treating animated and non-animated surfaces.
Patent WO-2022094055-A1 (WO)
Inventor: GOODCHILD ERIC HEINDEL
IPC: H02J50/80
Filed: 2021-10-28
Abstract: A wireless charging device has a controller and at least one coil that is positioned near the surface of the charging device and configured to transmit an electromagnetic field and a first driver circuit configured to drive the transmitting coil. The controller is configured to cause the driver circuit to provide a charging current to the transmitting coil, decode a request for lower transmission power from a modulation of the charging current, reduce the amplitude of the charging current in accordance with the request for lower transmission power when a temperature measured at a surface of the charging device is less than a threshold temperature, and initiate a cool down sequence when the temperature measured at the surface of the charging device equals or exceeds the threshold temperature. In one example, the request for lower transmission power may be provided in an ASK-modulated signal superimposed on the charging current.
Patent WO-2022103752-A1 (WO)
Title: Rapid construction of tetralin, chromane, and indane motifs via cyclative c-h/c-h coupling
Inventor: YU JIN-QUAN
IPC: C07C62/00
Filed: 2021-11-09
Abstract: Disclosed herein is a process for achieving a palladium-catalyzed cyclative C(sp3)-H/C(sp2)-H coupling reaction using a native free carboxylic acid as a directing group, an amino acid ligand, and oxidant. The process is useful for synthesizing a range of biologically important scaffolds, including tetralins, chromanes, and indanes.
Patent WO-2022108858-A1 (WO)
Inventor: SINN ERIC
IPC: E02F9/28
Filed: 2021-11-15
Abstract: Chacune de la pluralité d'encoches centrales (702) et des première et seconde encoches d'extrémité (724, 724') d'un bord de base (700) comprend une configuration différente comprenant une profondeur d'encoche d'extrémité différente (725) le long de la direction d'assemblage (714) qui est supérieure à une profondeur d'encoche centrale (725') le long de la direction d'assemblage (714).
Patent WO-2022119836-A1 (WO)
Title: Recovery of metals from lithium-ion batteries
Inventor: GRAF ALEJANDRO F
IPC: H01M10/0525
Filed: 2021-11-30
Abstract: The present disclosure provides methods and systems for recovering metals from lithium-ion batteries, and specifically to methods and systems for recovering cobalt and nickel jointly in metallic form via electrowinning processes. The present disclosure further provides methods and systems for preparing lithium-ion battery materials for use in metal recovery processes.
Patent WO-2022119984-A1 (WO)
Title: A system and method for the automatic configuration of devices by remote communication with a server
Inventor: MIMASSI NAGIB GEORGES
IPC: G06Q20/32
Filed: 2021-12-01
Abstract: A system and method comprising a server that automatically configures and sets up a restaurant's or business' information technology (IT) infrastructure, more specifically relating to point-of-sale devices (POS) and other networked devices such as scanners, tracking displays, and any other device that any business may use. Communication between the networked devices and the server is facilitated by a preconfigured router, wherein after initial communication with the server, the server may update firmware, operating parameters, and software packages of the preconfigured router and other networked devices.
Patent WO-2022125513-A1 (WO)
Title: Agent thérapeutique nutritionnel ciblant le cerveau pour une fonction cognitive améliorée et traitement d'un trouble cognitif léger
Inventor: MARSLAND CHARLES
IPC: A23L33/15
Filed: 2021-12-07
Abstract: Le problème à résoudre par la présente invention est qu'il n'existe aucun traitement médical disponible pour le déclin cognitif chez l'homme. La prévention par l'amélioration du mode de vie, notamment en matière d'alimentation, est le seul moyen de réduire le risque. Paradoxalement, le régime alimentaire moderne est celui qui augmente le risque de démence et détériore la fonction cognitive. Par conséquent, la solution selon la présente invention porte sur le fait qu'il est essentiel que de nouveaux procédés soient développés sur la base d'une thérapie nutritive.
Patent WO-2022250738-A1 (WO)
Inventor: MINASSA LORENZZO BREDA
IPC: E21B17/00
Filed: 2021-05-27
Abstract: A control module for operation of downhole well tools and apparatuses is disclosed. The control module can control multiple tools, electronics, subs, etc. based on one electronic input and optionally one hydraulic input from the wellhead or surface. The control module can transmit along selected electronic lines and optionally hydraulic lines in order to control specific apparatuses of the downhole well tools. By allowing a single electronic line from the surface or shut in to control multiple tools, total electronic complexity is reduced. A three conductor control module can control operations of up to twelve downhole tools, and a two conductor control module can control operations of up to six downhole tools, in some embodiments.
Patent WO-2022047494-A1 (WO)
Inventor: BRESLIN EOGHAN BRIAN
IPC: A63F3/00
Filed: 2021-08-27
Abstract: A hybrid card game apparatus is provided. The apparatus includes a playing surface having a set of card hand stations on which playing cards can be positioned, the set of card hand stations being distributed around a dealer position at a side edge of the playing surface, wherein a distance between the dealer position and a nearest edge of each of the set of card hand stations is at most 36 inches, a card sensor system positioned near each of the set of card hand stations to sense an identity of the playing cards positioned face down on the card hand station and generate card identification data enabling identification of the playing cards positioned on the card hand station. At least one network interface is connected to the card sensor systems and configured to transmit at least one of the card identification data and an identification of the playing cards.
Patent WO-2022159905-A1 (WO)
Inventor: JEROME KEITH R
IPC: C12N15/861
Filed: 2022-01-25
Abstract: Des modes de réalisation de la présente divulgation concernent des méthodes et des compositions destinées à réduire ou à éliminer une réactivation de HSV-1 latente dans une cellule. Dans certains modes de réalisation, la méthode consiste à administrer à une cellule infectée par HSV-1 un ou plusieurs virus adéno-associés auto-complémentaires (AAVsc) comprenant une ou plusieurs séquences codant une ou plusieurs méganucléases spécifiques du HSV-1. Dans certains modes de réalisation, la composition comprend un ou plusieurs virus adéno-associés auto-complémentaires (AAVsc) comprenant une ou plusieurs séquences codant une ou plusieurs méganucléases spécifiques du HSV-1.
Patent WO-2022164901-A1 (WO)
Inventor: KALYANARAMAN BALARAMAN
IPC: C07C273/00
Filed: 2022-01-26
Abstract: Dans la présente invention, les inventeurs ont substitué le groupe hydroxyle dans l'hydroxyurée (HU) à un cation de triphénylphosphonium (TPP) fixé à un groupe alkyle ayant différentes longueurs de chaîne, afin de générer une nouvelle classe de composés d'hydroxyurée ciblant les mitochondries (mito-HU). L'allongement de la longueur de la chaîne latérale alkyle augmente l'hydrophobicité des mito-HU et est en corrélation avec une inhibition accrue de la phosphorylation oxydative et des effets antiprolifératifs dans des cellules tumorales.