baber/WOPTO huggingface dataset:
Patent FI-915933-A0 (FI)
Inventor: MULLNER STEFAN
IPC: A61K38/08
Filed: 1991-12-17
Abstract: Short peptides of the formula I X-Y-A-B-C-Cys-D-E (I> in which A and B are an amino acid or a covalent bond, C and D are an amino acid or a substituted amino acid, E is a modified or unmodified amino acid or a covalent bond, X is a radical or hydrogen and Y is leucine or a covalent bond, or dimers of the peptides of the formula I with cystine as dimerisation component, the stereoisomeric forms thereof where appropriate or their physiologically tolerated salts, the preparation thereof, and their use for the treatment of diabetes mellitus are described.
Patent FI-922694-A0 (FI)
Inventor: MILLER THEODORE CHARLES
IPC: A61K31/382
Filed: 1992-06-10
Abstract: 1-[[(Dialkylamino)alkyl]amino]-4-substituted-thioxanthen-9-ones having the formula <CHEM>  wherein n is 2 or 3;     R<1> and R<2> are independently lower-alkyl; Q is a residue chosen from the group consisting of CH2NHR<3>, CH2N(R<4>)SO2R<7>, CH2NHCHO, CH=N-Ar, C(O)NR<5>R<6>, CH2N(R<4>)C(O)R<7>, CH2N(C2H5)CHO, and CH2N(R<4>)P(O)(O-lower-alkyl)2;     R<3> is hydrogen or lower-alkyl;     R<4> is hydrogen or lower-alkyl;     R<5> is hydrogen, lower-alkyl or Ar;     R<6> is hydrogen or lower-alkyl;     R<7> is lower-alkyl, or Ar;     R<8> is hydrogen, lower-alkyl, lower-alkoxy, or halogen; and Ar is phenyl or phenyl substituted with methyl, methoxyl, halogen or nitro; or a pharmaceutically acceptable acid-addition salt or solvate thereof, are disclosed as antitumor agents. Compositions containing the thioxanthenones and the method of use of thioxanthenones for treating tumors and cancer in mammals are also disclosed.
Patent FI-922963-A0 (FI)
Inventor: MISAWA SATURO
IPC: C07K14/815
Filed: 1992-06-26
Abstract: A secretion vector for foreign protein production, in particular hirudin HV1, hirudin HV3 and hirudin analog HV1C3, is provided comprising a replication origin (ori) of a pUC plasmid, a tac or a trp promoter, a DNA sequence encoding signal peptide, and a DNA sequence encoding a foreign protein, all linked in an operable manner. Also provided are a method of producing said hirudins and hirudin analog employing the secretion vectors, and transformed microorganisms such as E. coli.
Patent FI-941821-A0 (FI)
Inventor: TINGSKOG LENNART
IPC: B65G15/08
Filed: 1994-04-20
Abstract: PCT No. PCT/SE92/00733 Sec. 371 Date Jun. 20, 1994 Sec. 102(e) Date Jun. 20, 1994 PCT Filed Oct. 22, 1991 PCT Pub. No. WO93/08106 PCT Pub. Date Apr. 29, 1993.A belt conveyor comprises an endless conveyor belt (4) of the type surrounding the material conveyed and having a central part (5) and two edge parts (6, 7) connected thereto. The edge parts are substantially flexurally rigid in the transverse direction of the belt. The belt conveyor further comprises a frame having support rollers for carrying the belt along at least part of its path. The one edge part (6) of the belt (4) is divided into two portions closest to its free longitudinal edge so as to form a longitudinal pocket open towards the free longitudinal edge. The free edge portion of the other edge part (7) is received in the pocket so as to be substantially unable to rotate therein, and is forcedly retained owing to the connection of the edge parts to the central part. A rotary disc (15), tapering in the form of a wedge towards its periphery, is mounted in the frame so as to engage and widen the pocket to enable the introduction of the free edge portion of the other edge part (7) therein at a belt sealing location along the belt path.
Patent FI-944500-A0 (FI)
Inventor: WALD THOMAS STEPHEN
IPC: B41M5/337
Filed: 1994-09-28
Abstract: A binder formulation for improving the water resistance, especially the warm water resistance, of thermally-sensitive record material comprises a major proportion of an amide ammonium salt of a substantially non-esterified styrene/maleic anhydride copolymer and a minor proportion of polyvinyl alcohol.
Patent FI-951623-A0 (FI)
Inventor: DEKKER ANDRE
IPC: H03F3/343
Filed: 1995-04-05
Abstract: PCT No. PCT/FI96/00179 Sec. 371 Date Feb. 13, 1997 Sec. 102(e) Date Feb. 13, 1997 PCT Filed Apr. 2, 1996 PCT Pub. No. WO96/31947 PCT Pub. Date Oct. 10, 1996A base station receiver and a reception method in a CDMA cellular radio system includes, in each cell, at least one base station communicating with a plurality of mobile stations situated within its area. The base stations measure the direction angle of a signal arriving from each mobile station with respect to the base station, and communicate with the mobile stations using antenna beams that change in time. The angles of the greatest gain of the beams are adjusted according to signal components arriving from the mobile station. In order to provide detection of good quality without a great deal of calculation, the detection of the desired signal utilizes simultaneously several signals received from different mobile stations taking into account the incoming direction of the signals when selecting the signals.
Patent FI-952484-A0 (FI)
Inventor: NAUMANN DIRK
IPC: C25B1/00
Filed: 1995-05-22
Abstract: Prepn. of metal hydroxides and/or metal oxy-hydroxides from the corresp. metal ions and OH ions comprises forming the metal ions in a membrane electrochemical process by anodic dissolution of the corresp. metal in the anode compartment, forming the OH ions by redn. of water in a cathode compartment bounded by an anion exchange membrane and transferring the OH ions through this membrane into the anode compartment by the driving force of an electric field. The novelty is that the metal is dissolved at pH above 7 in the presence of a ligand (I).
Patent FI-953881-A0 (FI)
Inventor: STRAUBEL HANS
IPC: B22D11/04
Filed: 1995-08-17
Abstract: The continuous casting installation for production of thin strip incorporates an electromagnetic braking system for melt entering through an immersed pouring pipe (7) into the mould (2,3). The braking system comprises a coil (12) with a ferromagnetic core located next to each of the mould broad-sides, and a yoke surrounding the mould. The cores are made up of a main core (11) and an auxiliary core (14). The latter is exchangeable. Different auxiliary cores are used to adjust the magnetic field to different casting conditions.
Patent FI-973121-A0 (FI)
Inventor: MEIER ANTON
IPC: C08L61/30
Filed: 1997-07-25
Abstract: Aqueous aminoplast resins with a solids content of 50 to 75 wt % and a viscosity, related to a solids content of 67 wt %, of 150 to 400 mPa.s (measured at 20  DEG C and a shear gradient of 500 s<-1>) containing per mol melamine (component a) 0.5 to 13 mol urea (component b), 2 to 20 mol formaldehyde (component c), 0 to 1 mol phenol and/or a condensable phenol derivative (component d), 0 to 1 mol of an alkaline sulphite and/or alkaline hydrogen sulphite (component e) and 0 to 1 mol of a further condensable compound (component f), in which the ratio of the sum of the mol quantities of the (-NH2) groups originally present in components (a) and (c) to that of component (c) is 0.5:1 to 2:1.
Patent IL-80213-A0 (IL)
Title: Quinazoline derivatives,process for the preparation thereof and pharmaceutical compositions containing the same
IPC: C12N9/99
Filed: 1986-10-02
Abstract: A compound of the formula: 
<CHEM>
 in which
 R<1> and R<2> are each hydrogen, halogen, lower alkoxy or halo(lower)alkyl,
 R<3> is aryl or ar(lower)alkyl, both of which may have one or more suitable substituent(s), or heterocyclic(lower)alkyl,
 R<4> is carboxy or protected carboxy,
 A is oxygen or sulfur atom,
 Y is carbonyl, thiocarbonyl or sulfonyl and
 Z is lower alkylene,
 and pharmaceutically acceptable salts thereof, processes for their preparation and pharmaceutical compositions comprising them in admixture with pharmaceutically acceptable carriers.
Patent IL-88024-A0 (IL)
Title: Antibiotic solutions and the lyophilization thereof
IPC: A61K47/14
Filed: 1988-10-12
Abstract: Gel-free concentrated aqueous formulations of vancomycin hydrochloride are provided which comprise the antibiotic salt at a concentration between about 12% and about 50% w/v and a gel-inhibiting compound, e.g., ethanol, at a concentration between about 1% and about 20% v/v. The gel-free formulations are especially useful in a freeze-drying process for preparing vancomycin hydrochloride as a dry flowable powder in bulk or in unit-dosage form.
Patent IL-89657-A0 (IL)
Title: Mesotetraphenylporphyrin complex derivatives,process for the preparation thereof and pharmaceutical compositions containing the same
IPC: A61K31/40
Filed: 1989-03-17
Abstract: Porphyrin complex compounds, consisting of a meso-tetraphenyl- porphyrin ligand, if appropriate at least one ion of an element of atomic number 13, 21, 32, 37-39, 42-44, 49, 50 or 57-83 and, if appropriate, cations of inorganic and/or organic bases, amino acids or amino acid amides, are useful diagnostics and therapeutics.
Patent IL-92288-A0 (IL)
Title: Method of and apparatus for automatic frequency control
IPC: H04L27/14
Filed: 1989-11-13
Abstract: There is provided a method of and apparatus for Automatic Frequency Control (AFC) in the presence of data. It comprises removing the effects of data modulated onto the carrier (25), detecting the frequency difference between the carrier frequency and the phase of the reference oscillator (30), and adjusting (80) the frequency of the reference oscillator (35) to eliminate the frequency difference ( DELTA ). It is further characterized by digitizing (40) the modulated carrier in quadrature, sampling (20) the modulated carrier in quadrature at a multiple of the modulated bit rate, rotating phases toward arctangent (I/Q)=0 (25/55/60) to remove the effects of quadrature data (I/Q) modulated onto the carrier, detecting (30) the frequency difference ( DELTA ) between the carrier frequency and the frequency of a Voltage Controlled type of reference oscillator (35) with a phase trajectory estimator (45), and establishing and generating the requisite correction voltage ( DELTA ) for a Voltage Controlled type of reference oscillator (VCO) (35) with the phase trajectory estimator (45). <IMAGE>
Patent AU-PN200695-A0 (AU)
Title: Transaminase reagent
IPC: C12Q1/32
Filed: 1995-03-28
Abstract: This invention relates to a reagent for enzymatic determination of an analyte concentration in a patient wherein the degree of oxidation of a coenzyme is measured, characterized in that said reagent is stabilized against oxidation by a coenzyme reduction system comprising an enzyme and substrate pair selected so as to enable continuous regeneration of said coenzyme throughout storage of said reagent. Also disclosed is an improvement in an enzymatic method of determination of an analyte concentration in a sample body fluid wherein the degree of oxidation of a coenzyme is measured, the improvement comprising stabilizing a reagent comprising said coenzyme against oxidation by a coenzyme reduction system comprising an enzyme and substrate pair selected so as to enable continuous regeneration of said coenzyme throughout storage of said reagent. Also disclosed are reagents for the determination of aspartate aminotransferase, alanine aminotransferase, ammonia and urea.
Patent AU-PP229498-A0 (AU)
Title: Endotracheal tube for selective bronchial occlusion
IPC: A61M16/04
Filed: 1998-03-11
Abstract: An endotracheal tube (1) for selective bronchial occlusion for use in medical and surgical procedures in hospitals, and for on-site post-trauma medical stabilisation procedures, where it is often necessary to intubate the lungs with a view to isolating and occluding one lung and ventilating the other lung, the endotracheal tube (1) having a central channel (5) extending throughout its entire length with an opening at each of opposed distal (3) and proximal (4) ends thereof, the opening at the proximal end of the tube being adapted for connection to a ventilation device and the opening at the distal end comprising a first or distal air vent for venting air into the lungs, the bronchial/tracheal tube having separate spaced apart distal and proximal peripherally inflatable portions (6 and 7) at the distal end of the tube and at a proximal location relative thereto, respectively, and a second or proximal air vent opening (8) in the sidewall of that portion of the tube extending between the distal and proximal inflatable portions (6 and 7) wherein the distal inflatable portion (6) is inflatable both radially outwardly (as at 9) adapted to seal against the surrounding bronchus and radially inwardly (as at 10) to seal against itself to occlude the lumen of the tube (5) and wherein the proximal inflatable portion (7) is inflatable radially outwardly (as at 11) adapted to seal against the surrounding bronchial tube.
Patent IL-102643-A0 (IL)
Title: Process for preparing s-(+)-2,2-dimethylcyclopropanecarboxamide using microorganisms transformed by recombinant techniques
IPC: C12N15/55
Filed: 1992-07-26
Abstract: A genetic engineering process for the preparation of S-(+)-2,2-dimethylcyclopropanecarboxamide is described. For this, a DNA which codes for a stereospecific hydrolase is isolated from a microorganism. This DNA is then ligated into an expression vector, resulting in a hybrid plasmid which is transformed into microorganisms. These microorganisms are then capable of the biotransformation of the R-(-) isomer in racemic R,S-(+/-)-2,2-dimethylcyclopropanecarboxamide to the R-(-)-2,2-dimethylcyclopropanecarboxylic acid, resulting in optically active S-(+)-2,2-dimethylcyclopropanecarboxamide. <IMAGE>
Patent IL-111958-A0 (IL)
Title: Absorbent body in an absorbent product
IPC: A61F13/15
Filed: 1994-12-12
Abstract: PCT No. PCT/SE94/01259 Sec. 371 Date May 21, 1996 Sec. 102(e) Date May 21, 1996 PCT Filed Dec. 27, 1994 PCT Pub. No. WO95/17870 PCT Pub. Date Jul. 6, 1995Absorbent body in an absorbent product such as a diaper, incontinence pad, sanitary napkin or the like, and which comprises a liquid acquisition portion (13; 11, 13) and a liquid storage portion (12) adjacent thereto. The liquid acquisition portion has at least one well (13) which is located at the assumed wetting area of the absorbent body and extends into and through the liquid storage portion (12) and is in liquid communication with a liquid wicking layer (14) arranged under the liquid storage layer (12). The material in the liquid acquisition portion (13; 11, 13) has a mean pore size which is greater than the mean pore size in the liquid storage portion (12). The absorbent body has a high instantaneous absorption even during repeated wetting and a low rewetting.
Patent IL-114438-A0 (IL)
Title: Method and apparatus for forming flanges on tubes
IPC: B29B13/02
Filed: 1995-07-04
Abstract: A process for forming an integral flange (8) on a tube (1) made from cross-linked, partially crystalline thermoplastics, esp. polyolefin involves (a) clamping the tube (1) so that an unsupported length projects from the clamped length; (b) heating the inside and outside of the projecting length and inside the tube (1) at the boundary (3) between clamped and free sections; (c) axially compressing the projecting tube end to form a bulge which folds to form two annular discs (6, 7); (d) cooling the radially outer edges of the discs (6, 7) to produce progressive partial crystallisation and stabilise the flange created by both discs (6, 7). Claimed process equipment includes a shell-like tool (10) in two parts, with a smaller dia. part for holding the tube (1) and a larger dia. part for forming the flange. A heater fits into the tool (10), heats both inner and outer tube walls, extends over the full length of the projecting end externally, beyond the projecting length internally and has a dia. larger than the formed flange. A forming ram (30) has a contact face (34) for the tube end (4) and is divided into cooling (33) and non-cooling (31, 32) areas. The non-cooling areas (31, 32) are at a temp. which induces no new partial crystallinity into the plastic and the cooling area (33) temp. creates partial crystallinity.
Patent IL-114523-A0 (IL)
Title: Priming mixture containing no toxic materials and cartridge percussion primer employing such a mixture
IPC: C06C7/00
Filed: 1995-07-10
Abstract: A priming mixture containing no toxic materials, in particular no Pb, Ba or Sb compounds, and presenting at least one primary explosive, an oxidizing agent, a reducing agent, and an inert friction agent; the oxidizing agent comprising stannic oxide SnO2. The central-fire or rimfire percussion primer presents a casing containing the priming mixture, and, in the case of the central-fire primer, also an anvil.
Patent IL-115102-A0 (IL)
Title: Crystalline form of dihydro-2,3-benzodiazepine derivative
IPC: C07D493/04
Filed: 1995-08-30
Abstract: A physical form of (R)-7-acetyl-5-(4-aminophenyl)-8,9-dihydro-8-methyl-7H-1,3-dioxoloÄ4,5 -hÜÄ2,3Übenzodiazepine of formula I having an X-ray powder diffraction pattern with d spacings at 12.78, 9.48, 8.99, 8.64, 8.23, 6.39, 6.27. 5.73, 4.01 and 3.96  ANGSTROM . The compound is useful as an AMPA antagonist. <CHEM> R is methyl, X is acetyl and Aryl is p-nitrophenyl.i
Patent IL-116829-A0 (IL)
Title: Device for packing under vacuum
IPC: B65B31/02
Filed: 1996-01-19
Abstract: Device for the packing under vacuum of products contained in flexible bags in plastic material, where means are provided suitable to create, around the opening of the bag, an airtight chamber connected to air suction devices, being provided welding devices suitable to weld the bag walls along a line beyond said chamber, in order to seal the bag after creating the vacuum inside it through said suction means. <IMAGE>
Patent IL-130275-A0 (IL)
Title: Tape feeder for a stitching machine
IPC: B65H16/06
Filed: 1999-06-03
Abstract: A tape feeder for feeding elasticized tape to a stitching machine adapted for stitching the elasticized tape onto a textile workpiece, the tape feeder comprising a tensioning assembly comprising a tensioning assembly comprising a gearbox fitted with a first shaft and a second shaft substantially orthogonal to one another and rotationally coupled to one another via suitable first coupling mechanism and a first roller. A presser mechanism comprising a second roller mounted onto a releasable bracket such that the first and second roller are maintained essentially parallel and biased towards one another for grippingly passing elasticized tape therebetween in response to rotation of one of the rollers. The first and second shaft have a free end for selectively coupling to a suitable driving member. And a mounting structure mountable onto the stitching machine, for supporting the gearbox assembly in either a first position and a second position being in substantially orthogonal relation to one another. <IMAGE>
Patent IL-133989-A0 (IL)
Title: Chemical compounds
IPC: A61K31/00
Filed: 1998-08-04
Abstract: The invention concerns the use of a compound of formula (I), in which Z, X, T, A, R<SUP>1</SUP>, R<SUP>2</SUP>, p and q have any of the meanings defined herein, and their pharmaceutically acceptable salts or in vivo hydrolysable esters, in the treatment of a disease or condition mediated by monocyte chemoattractant protein-1 (MCP-1). Certain of the components of formula (I) are novel and are provided, together with pharmaceutical compositions thereof, as further features of the invention.
Patent IL-143225-A0 (IL)
Title: TREATMENT OF RUMEN ACIDOSIS WITH α-AMYLASE INHIBITORS
IPC: A23K1/14
Filed: 2001-05-17
Abstract: Inhibitors of rumen bacterial alpha-amylase and/or alpha-glucosidase are useful in the preparation of medicaments for the curative, palliative and prophylactic treatment of rumen acidosis and secondary conditions of rumen acidosis.
Patent IL-187176-A0 (IL)
Title: Non-pneumatic vehicle tire
Filed: 2007-11-05
Abstract: A non-pneumatic tire for a vehicle featuring a body (1) of elastic material and having a circumferentially-extending crown portion (1.1) featuring a running surface and circumferentially-extending sidewalls (1.3) joined to the crown portion. The side walls terminate in circumferentially-extending beads (1.4) which are adapted to engage the rim (5) of a vehicle wheel. A number of radially-extending and circumferentially-spaced compound-curve springs (2) made of a composite material are at least partially embedded within the crown portion and the sidewalls. The curved springs have ends (4) terminating within the beads of the tire body. A circumferentially-extending belt (3) constructed of a high-strength and low stretch material is positioned radially outside of the compound-curve springs.
Patent IL-197296-A0 (IL)
Title: Use of imatinab for the manufacture of a medicament for the treatment of philadelphia positive -leukemia
Filed: 2009-02-26
Abstract: The present invention provides a method of treating Philadelphia positive (Ph+) leukemia, such as Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ ALL) or chronic myeloid leukemia (CML), in a human patient population comprising the steps of 
(a) administering a predetermined fixed amount of a Bcr-Abl tyrosine kinase inhibitor, such as Imatinib, or a pharmaceutically acceptable salt thereof to human patients suffering from a Ph+ leukemia, 
(b) collecting at least one blood sample from said patients, 
(c) determining the plasma trough level (Cmin) of the Bcr-Abl tyrosine kinase inhibitor or of a metabolite thereof as well as the MMR rates, 
(d) assessing a discrimination potential of trough plasma concentrations for MMR and identifying a Cmin threshold for optimal sensitivity and specificity and 
(e) adjusting the dose of the inhibitor of the Bcr-Abl tyrosine kinase or a pharmaceutically acceptable salt thereof applied to the individual patients from said patient population and, optionally, future patients suffering from a Ph+ leukemia in a manner that a Cmin is achieved in each single patient equal to or higher than the Cmin threshold obtained under step (d).
Patent IL-206226-A0 (IL)
Title: Compounds for the selective treatment of the intestinal immuno-inflammatory component of the celiac disease
Filed: 2010-06-07
Abstract: In one aspect, the present invention relates to amino-salicylic - aminophenylpropionic compounds for the use in the treatment of the inflammatory component of the celiac disease. These compounds act by blocking the cytokines released in the celiac disease and are specifically useful in the treatment of cases refractory to the diet, in dietary errors and in the reduction of the celiac disease remission time.
Patent RO-129611-A0 (RO)
Title: Clockwork accumulating the energy developed by the actuation spring
Inventor: NAGY CSABA SANDOR
IPC: G04B13/02
Filed: 2014-01-13
Abstract: The invention relates to a clockwork accumulating the energy developed by the actuation spring, meant for any mechanical timepiece, either wrist watches or table or wall clocks, spring- or weight-actuated, for extending the clockwork operation time. According to the invention, the mechanism consists of an actuation toothed wheel () integral with an actuation spring () by means of an arbor () of square cross-section , a retensioning toothed wheel () mounted along with an actuation spring () between two plates (), i.e. an upper plate and a lower plate, an internally toothed ring () making one piece with a case () of the timepiece and coupling with the actuation toothed wheel (), an internally toothed ring () rigidly connected with the case () and engaging the retensioning toothed wheel (), a guiding staff () aligned with another staff () on which there is a minute hand toothed wheel (), the clockwork also having a closing plate () integral with the guiding staff ().