Patent SG-11201808152P-A (SG)
Title: Dna antibody constructs and method of using same
Inventor: WEINER DAVID
IPC: C12N9/64
Filed: 2017-03-21
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) CORRECTED VERSION ,11,,,„,,,,,, ,,,„,1111111111111111111111111111 111111 1111111111111111111111111111111111111 (19) World Intellectual Property Organization International Bureau --, (10) International Publication Number (43) International Publication Date ...../ WO 2017/165460 A9 28 September 2017 (28.09.2017) WIP0 I PCT (51) International Patent Classification: (84) Designated States (unless otherwise indicated, for every A61K 39/00 (2006.01) Cl 2N 9/64 (2006.01) kind of regional protection available): ARIPO (BW, GH, C12N 9/48 (2006.01) GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, (21) International Application Number: UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, PCT/US2017/023479 TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, (22) International Filing Date: MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, 21 March 2017 (21.03.2017) TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). (25) Filing Language: English (26) Publication Language: English Published: (30) — with Priority Data: — with 62/311,316 21 March 2016 (21.03.2016) US international search report (Art. 21(3)) sequence listing part of description (Rule 5.2(a)) 62/332,381 05 May 2016 (05.05.2016) US (48) Date of publication of this corrected version: 62/376,162 17 August 2016 (17.08.2016) US 09 November 2017 (09.11.2017) 62/396,748 19 September 2016 (19.09.2016) US (15) Information about Correction: — 62/396,750 19 September 2016 (19.09.2016) US see Notice of 09 November 2017 (09.11.2017) 62/417,093 03 November 2016 (03.11.2016) US 62/429,454 02 December 2016 (02.12.2016) US = 62/429,473 02 December 2016 (02.12.2016) US Inventors; and (72) — Applicants: WEINER, David, B. [US/US]; 717 Beacom (71) Lane, Merion, PA 19066 (US). MUTHUMANI, Karup- = piah [US/US]; 52 Ivy Lane, Cherry Hill, NJ 08002 (US). FLINGAI, Seleeke [US/US]; 1623 Penn Avenue North, = Minneapolis, MN 55411 (US). SARDESAI, Niranjan _ = 480 Mallard Circle, Blue Bell, PA 19422 (US). = [US/US]; ELLIOTT, Sarah [US/US]; P.O. Box 301, Pullman, WA 99163 (US). YAN, Jian [US/US]; 503 Sheffield Drive, = Wallingford, PA 19086 (US). PATEL, Ami [US/US]; 1 = Rainey Court, Philadelphia, PA 19103 (US). = (74) Agent: SLAUGHTER, Alison P. et al.; Riverside Law, = LLP, Glenhardie Corporate Center, 1285 Drummers Lane, = Suite 202, Wayne, PA 19087 (US). Designated States (unless otherwise indicated, for every (81) = kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, = CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, = KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, _ 0\ PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, 71' TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. kr) Il (54) Title: DNA ANTIBODY CONSTRUCTS AND METHOD OF USING SAME C 1-1 (57) : Disclosed herein is a composition comprising the combination of a nucleic acid sequence encoding a desired polypeptide N that elicits an immune response in a mammal and a nucleic acid sequence encoding an antibody, a fragment thereof, a variant thereof, or a combination thereof.