baber/WOPTO huggingface dataset:
Patent EP-3930745-A1 (EP)
Inventor: BRENNER GARY J
IPC: A61K39/112
Filed: 2020-02-27
Abstract: Compositions and methods for the treatment of benign nervous system tumors including schwannomas using attenuated  Salmonella typhimurium  and optionally one or more checkpoint inhibitors.
Patent EP-4013875-A1 (EP)
Inventor: BOUTIN ADAM T
IPC: C12N15/113
Filed: 2020-08-14
Abstract: The present disclosure relates to modified extracellular vesicles, e.g., exosomes, comprising an antisense oligonucleotide (ASO), which is capable of reducing and/or inhibiting expression of STAT3 mRNA and/or STAT3 protein. ASOs that can be used with the modified extracellular vesicles are also disclosed. Also provided herein are methods for using the exosomes and ASOs to treat and/or prevent diseases, such as cancer.
Patent EP-4028073-A1 (EP)
Title: Système et procédé pour ouvrir un contenant de concentré et relier le contenant de concentré à un dispositif de traitement du sang
Inventor: BREHM WINFRIED
IPC: A61M1/16
Filed: 2020-09-10
Abstract: La présente invention concerne un système et un procédé pour ouvrir un contenant de concentré sans avoir besoin d'un être humain pour manipuler directement le contenant de concentré et relier le contenant de concentré à un dispositif de traitement du sang. Des aspects de l'invention concernent un contenant pour concentré et un dispositif de traitement du sang.
Patent EP-4046322-A1 (EP)
Inventor: FAHER MOURAD
IPC: H04L9/32
Filed: 2020-09-28
Abstract: A device comprises a hash tree (90) including a root node (92) and a leaf node. An issuing authority (50) agreed to generate a signature of the root node after having successfully checked validity of an attribute stored in the leaf node (24). The device identifies a subset (60) of nodes by using a template specifying the structure of the hash tree, said subset comprising, for all paths of the hash tree that do not comprise said leaf node, the node which is the closest to the reference root node and which does not belong to the path comprising said leaf node. The device provides a verifier (70) with the root node, said signature, attribute and subset. The verifier computes a test hash by using said attribute then computes a test root node by applying a preset rule to said test hash and subset. The verifier checks that said test root node and root node are equal and that the signature is valid using a data (76) whose authenticity is certified by the issuing authority.
Patent EP-4049519-A1 (EP)
Inventor: MAUER JAKOB
IPC: H05K7/20
Filed: 2020-09-23
Abstract: La présente invention concerne un procédé de détermination d'un débit volumique cible (V) d'un fluide de refroidissement qui est guidé à travers un trajet de fluide de refroidissement afin de refroidir un convertisseur de puissance, la température (TC) d'un condensateur à liaison en courant continu du convertisseur de puissance et de la température (TK) du fluide de refroidissement étant déterminées, et une valeur de débit volumétrique cible (V) étant déterminée sur la base de la température (TC) du condensateur à liaison en courant continu et la température (TK) du fluide de refroidissement.
Patent EP-4031957-A1 (EP)
Inventor: KIES JONATHAN
IPC: G06K9/00
Filed: 2020-09-11
Abstract: A device may be configured to determining display properties for virtual content in an environment with a plurality of physical participants by capturing an image of the environment, analyzing the captured image to identify at least one object in the environment, determining a parameter for the identified object, and determining a display property of a digital representation of virtual content based on the determined parameter. Embodiments may include negotiating display properties with other devices to generate coordinated display properties, and rendering the digital representation of the virtual content so that the remote participant appears to be in the same fixed position to all co-located participants and sized consistent with the co-located participants.
Patent EP-4034248-A1 (EP)
Inventor: SANTUCCI PEREIRA DEL BUONO JULIA
IPC: A61P35/00
Filed: 2020-09-24
Abstract: The disclosure provides a method for treating a subject afflicted with a cancer comprising administering to the subject a therapeutically effective amount of an anti-PD-1 antagonist, e.g., an anti-PD-1 or anti-PD-L1 antibody, in combination with an indoleamine 2,3-dioxygenase inhibitor, wherein the subject is identified as exhibiting a combined biomarker comprising (a) a high  IFNγ  inflammatory signature score and (b) a low tryptophan 2,3-dioxygenase 2 ( TDO2 ) gene expression score. The high  IFNγ  inflammatory signature score is determined by measuring the expression of a panel of  IFNγ  related inflammatory genes in a cancer sample obtained from the subject, wherein the gene panel comprises, e.g.,  IFNγ, CXCL10, CXCL9, HLA-DRA, IDO1 , and  STAT1 . In some aspects, the gene panel further comprises  CCR5, CXCL11, GZMA , and  PRF1 . In some aspects, the gene panel comprises  CXCR6, TIGIT, PD-L1, PD-L2, LAG3, NKG7, PSMB10, CMKLR1, CD8A, IDO1, CCL5, CXCL9, HLA.DQA1, CD276, HLA.DRB1, STAT1, HLA.E , and  TDO2 .
Patent EP-3957989-A1 (EP)
Inventor: TSUMURA KYOSUKE
IPC: G16B35/20
Filed: 2020-04-02
Abstract: An object of the present invention is to provide a method, a program, and a device which enable calculation of a feature quantity accurately indicating chemical properties of a target structure. Further, another object of the present invention is to provide a method and a program which enable efficient screening of a pharmaceutical candidate compound using a feature quantity. Further, still another object of the present invention is to provide a method which enables efficient creation of a three-dimensional structure of a pharmaceutical candidate compound using a feature quantity. In a case where target structures have a similarity in the degree of accumulation of probes, this indicates that the target structures have similar chemical properties. That is, target structures having similar feature quantities calculated according to the first aspect exhibit similar chemical properties. Therefore, according to the first aspect, the feature quantity accurately showing the chemical properties of a target structure can be calculated.
Patent EP-4045588-A1 (EP)
Title: Polymer composition comprising a recycled coated polyolefin fabric substrate
Inventor: TRAN Tuan Anh
IPC: C08L23/08
Filed: 2020-10-15
Abstract: The present invention relates to a polymer composition comprising the following components: A) 5 to 35 wt.-% based on the overall weight of the polymer composition of a recycled polyolefin fabric substrate; wherein said fabric substrate is coated with a polyolefin composition comprising the following components: a1) an ethylene based plastomer with a density determined according to ISO 1183-1 in the range of 0.857 to 0.915 g/cm3 and a MFR2 (190°C, 2.16 kg) determined according to ISO 1133 in the range of 0.5 to 30 g/10 min; and a2) a propylene based plastomer with a density determined according to ISO 1183-1 in the range of 0.850 to 0.910 g/cm3 and a MFR2 (230°C, 2.16 kg) determined according to ISO 1133 in the range of 0.01 to 30 g/10 min; B) 65 to 95 wt.-% based on the overall weight of the polymer composition of a homopolypropylene or a recycled polymer blend comprising b1) polypropylene and b2) polyethylene, wherein the weight ratio of b1) to b2) is from 3:7 to 12:1; with the proviso that components A) and B) add up to 100 wt.-%. Furthermore, the present invention relates to use of component A) for increasing the Charpy Notched Impact Strength of component B) and to an article comprising the polymer composition according to the present invention.
Patent EP-4021483-A1 (EP)
Inventor: MÜLLER JÖRG
IPC: A61K38/48
Filed: 2020-10-12
Abstract: Die vorliegende Erfindung liegt auf dem Gebiet der Radioonkologie. Dabei umfasst das erfindungsgemäße Verfahren die Verwendung von Botulinumtoxin und einem Anticholinergikum zur Vermeidung von Strahlenschäden und Nebenwirkungen durch Radioliganden an Drüsen. Ferner umfasst das erfindungsgemäße Verfahren auch die Verwendung von Botulinumtoxin zur Vermeidung von Strahlenschäden der Drüsen, wobei die Strahlenschäden von Radioliganden hervorgerufen werden. Durch das erfindungsgemäße Verfahren kann die vorliegende Erfindung einen wirksamen Drüsenschutz zur Vermeidung von Strahlenschädigung bereitstellen.
Patent EP-3960241-A1 (EP)
Inventor: MASUDA MICHIAKI
IPC: A61K31/197
Filed: 2020-04-24
Abstract: Provided are an agent for preventing and/or treating a flavivirus infectious disease and a method for preventing and/or treating a flavivirus infectious disease. At least one selected from 5-aminolevulinic acid (5-ALA), a 5-ALA ester, a salt of 5-ALA, or a salt of the 5-ALA ester is used in the agent for preventing and/or treating the flavivirus infectious disease. Examples of the flavivirus to be prevented or treated by 5-ALA or the like can include dengue virus, Zika virus, Japanese encephalitis virus, tick-borne encephalitis virus, West Nile virus, and yellow fever virus.
Patent EP-3976182-A1 (EP)
Inventor: TAGAYA YUTAKA
IPC: A61P17/14
Filed: 2020-04-30
Abstract: The yc-family cytokines, Interleukin-2 (IL-2), Interleukin-4 (IL-4), Interleukin-7 (IL-7), Interleukin-9 (IL-9), Interleukin-15 (IL-15), and Interleukin-21 (IL-21), are associated with important human diseases, such as alopecia and alopecia associated disorders. Compositions, methods, and kits to modulate signaling by at least one yc-cytokine family member for inhibiting, ameliorating, reducing a severity of, treating, delaying the onset of, or preventing at least one alopecia related disorder are described.
Patent EP-4044929-A1 (EP)
Inventor: DIRCKX CONRAD
IPC: A61B6/02
Filed: 2020-10-12
Abstract: Image quality for flat-panel array tomosynthesis acquisition is not equivalent to CT because of the reduced number of image angles that are acquired in DT, and also image quality is not uniform throughout the volume and decreases near to the fixed detector array and the fixed flat-panel source. The present invention provides a system for obtaining an X-ray image of a subject (1) in which an emitter panel (3) and detector (7) are movable on a smart armature (9). In this way, image quality can be improved, for example by combining acquisitions taken from different orientations, thereby approaching the quality of conventional CT imaging, whilst still maintaining the lower cost and dose of conventional DT imaging.
Patent EP-3968811-A1 (EP)
Inventor: YUAN JONNY
IPC: A45F5/00
Filed: 2020-04-27
Abstract: A case for a portable electronic device (PED) is disclosed. The case includes a body having an interior surface configured to accept a PED and an exterior surface to be exposed to outside forces. A back vent that permits the transfer heat away from the PED and to the environment presents through the body of the case. A cushioning member is placed at or near the back vent on the interior surface of the case and may substantially or completely surround the back vent. When a PED is placed within the case, the fit of the PED and the case causes the cushioning member to press against the PED in order to create a cushion for the PED in the event of an outside force being applied to the case. The case may include a screen protector within a frame that attaches to the body.
Patent EP-3972019-A1 (EP)
Title: Power supply battery and power supply system for high-speed maglev trains
Inventor: LIANG JIANYING
IPC: H01M12/06
Filed: 2020-05-11
Abstract: A power supply battery and a power supply system for high-speed maglev trains. The power supply battery comprises: an electrolyte tank (10), a plurality of liquid flow pumps (20), and a plurality of aluminum-air battery reactors (30). The plurality of aluminum-air battery reactors (30) are sequentially connected in series. The electrolyte tank (10) comprises a plurality of elongate electrolyte grooves (101). One liquid flow pump (20) corresponds to one aluminum-air battery reactor (30) and one electrolyte groove (101). The power supply battery and the power supply system for high-speed maglev trains have the advantages of long-term storage without power loss, high energy density, high safety, abundant resources, low manufacturing costs and cleanliness and easy recovery by adopting aluminum-air batteries as the power supply of an on-board energy storage system of a high-speed maglev train. Moreover, a high voltage of the whole power supply battery can be ensured, self-discharge is reduced, high integration of the aluminum-air batteries is facilitated, the installation space is reduced, continuous work is realized, and energy can be continuously provided for maglev train loads.
Patent EP-4111551-A1 (EP)
Title: Steckverbinderelement mit verriegelungseinrichtung
Inventor: BENZIN MARIAN
IPC: H01R13/629
Filed: 2020-11-17
Abstract: Steckverbinderelement mit einer Verriegelungseinrichtung (14) zur lösbaren Verriegelung an einem Steckpartner (12), wobei die Verriegelungseinrichtung eine Anzahl von auf dem Umfang eines Grundkörpers (10) verteilten Verriegelungshaken (16, 18) aufweist, die jeweils an einem in Steckrichtung vorderen Ende gekröpft sind und in radialer Richtung zwischen einer Verriegelungsstellung und einer Freigabestellung schwenkbar sind, dadurch gekennzeichnet, dass die Verriegelungshaken (16, 18) als voneinander und von dem Grundkörper (10) getrennte Bauteile ausgebildet sind, die so am Grundkörper gelagert sind, dass sie jeweils um eine rechtwinklig zur Einsteckrichtung und rechtwinklig zur Radialrichtung verlaufende Achse kippbar sind, und die jeweils am der Kröpfung entgegengesetzten Ende in Axialrichtung federnd am Grundkörper abgestützt sind.
Patent EP-4062457-A1 (EP)
Inventor: GIJSMAN PIETER
IPC: H01L31/048
Filed: 2020-11-20
Abstract: The present invention relates to a photovoltaic module backsheet, comprising photovoltaic module backsheet comprising, in order: a functional layer; a connecting layer; and a weather-resistant layer, wherein each layer of the backsheet comprises at least 50 wt.% polyolefin and the backsheet is free of fluorinated polymers, characterized in that: i) the functional layer comprises a blend of polyethylene and a polyethylene copolymer; and ii) the weather-resistant layer comprises polypropylene; a UV stabilizer; a primary antioxidant, which primary antioxidant is a phenolic antioxidant or an aromatic amine antioxidant; and secondary antioxidant, which secondary antioxidant is a trivalent phosphorus containing antioxidant or a thioether containing antioxidant. The present invention also relates to a process for producing the backsheet and a photovoltaic module comprising the backsheet according to the present invention.
Patent EP-4003592-A1 (EP)
Inventor: BELLIERE-BACA VIRGINIE
IPC: B01J37/08
Filed: 2020-07-31
Abstract: The invention relates to a process for producing a multiphase, mixed-oxide catalyst comprising at least one bismuth molybdate-based active phase and a co-catalyst based on iron molybdate and at least one of the two elements cobalt and nickel, said process comprising the following steps: preparing a mixture of the precursors of said mixed oxides in a solvent, reacting said precursors by microwave-assisted hydrothermal reaction, and isolating the mixed oxides in order to obtain the catalyst. The subject matter of the invention is made up of a catalyst and a catalytic system thus prepared and also the uses of this catalyst and this catalytic system, in particular in the oxidation of propene to acrolein.
Patent EP-4073272-A1 (EP)
Inventor: HOSSEINIAN EHRENSBERGER SAHAR
IPC: C12Q1/6883
Filed: 2020-12-10
Abstract: The present invention relates to methods for determining biomarker signatures that are relevant for detecting a disease in a patient or identifying altered abundance of cells within the patient. Also disclosed are methods for detecting a disease or altered cell type abundance in a patient by measuring said biomarker signature for at least one cell type.
Patent EP-3984231-A1 (EP)
Title: Methods and system of subblock transform for video coding
Inventor: XIU XIAOYU
IPC: H04N19/44
Filed: 2020-06-12
Abstract: A computing device performs a method of decoding video data by receiving, from a bitstream, a first syntax element associated with an SBT coding unit that indicates that there exists at least one non-zero transform coefficient in the SBT coding unit; determining a first transform unit that includes non-zero transform coefficients; receiving a second syntax element associated with a first chroma component of the first transform unit, a third syntax element associated with a second chroma component, and a fourth syntax element associated with luma component of the first transform unit; decoding the transform coefficients of chroma and luma components of the first transform unit, based on the second, third and fourth syntax elements; and setting transform coefficients of luma and chroma components of rest of the plurality of transform units to zeros.
Patent EP-4069037-A1 (EP)
Inventor: CARNELOS LUCA
IPC: A47B95/00
Filed: 2020-11-23
Abstract: Angular support device (1) adapted to support a wall cabinet on a wall, said device (1) comprising:- hooking means (3) adapted to cooperate with engagement means wall-fixed to support the piece of furniture, and- a mounting body (2) comprising a support plate (10) whereon said hooking means (3) can be mounted, and a mounting plate (20) which can be integrally constrained to the inner surface of the side of a piece of furniture, said support plate (10) and said mounting plate (20) being arranged, in use, on mutually perpendicular planes so that said mounting body (2) is dihedral-shaped, characterised in that said support plate (10) and said mounting plate (20) are made of respectively distinct and separate pieces, guide means (40) being provided on said mounting plate (20) to allow the coupling with said support plate (10) during assembly, said mounting plate (20) further comprising retaining means (44) movable between a neutral position and a retaining position during assembly for maintaining the assembly of said mounting body (2).
Patent EP-4037480-A1 (EP)
Inventor: MÉNARD SERGE
IPC: A01K61/60
Filed: 2020-10-05
Abstract: Deep-sea aquaculture installation (1) comprising a buoyant and submersible base structure (2) and a semi-submersible superstructure (6). The base structure (2) comprises one or more cages (3) that are open to open water on two opposite sides. The base structure (2) comprises at least two buoyancy volumes (5) that are situated along each of the side faces of the base structure. The superstructure (6) comprises one or more buoyancy volumes (7), in particular in its upper part. The superstructure (7) has, at least in its upper two thirds, the shape of a column (25) that extends vertically above the centre of gravity (C) of the base structure (2). The area of the largest horizontal section (S) of this superstructure (7) in the upper two thirds is less than 5% of the total maximum area of a horizontal cross section (S') of the base structure (2).
Patent EP-4069131-A1 (EP)
Inventor: BARATZ ADAM
IPC: A61C5/50
Filed: 2020-12-03
Abstract: Disclosed herein is an obturator and methods of manufacturing an obturator for filling an endodontically prepared root canal. The obturator comprises an elongated carrier having a distal end, proximal end, and working portion with a combination of filler materials having multiple viscosities coated on the working portion.
Patent EP-3992906-A1 (EP)
Title: Information processing method and information processing system
Inventor: TAKAHASHI MASAKI
IPC: G06T7/00
Filed: 2020-04-03
Abstract: An information processing method is executed by a computer and includes acquiring a first recognition result that is output as a result of inputting sensing data to a first recognition model trained through machine learning (S10), acquiring reference data for the sensing data (S20), determining a difference in class of a recognition target between the first recognition result and the reference data (S30), generating an additional class for the first recognition model when the difference satisfies a predetermined condition (Yes in S30) (S70), and outputting the sensing data or processed data obtained by processing the sensing data as training data for the additional class (S80).
Patent EP-3994259-A1 (EP)
Title: Improved mannanase variants
Inventor: JUNTUNEN KARI
IPC: A23K20/189
Filed: 2020-06-16
Abstract: A variant of mannanase is disclosed having at least 90% sequence identity with SEQ ID NO: 1 and a substitution of an amino acid in position 256. An enzyme composition, detergent composition, host cell, animal feed, and feed supplement comprising the present variant are disclosed, as well as methods and uses involving the present variant.
Patent EP-4082182-A1 (EP)
Inventor: SCHWAB JUSTIN J
IPC: H04N5/225
Filed: 2020-12-22
Abstract: L'invention concerne des indicateurs d'enregistrement pour des dispositifs avec des caméras qui fournissent une protection contre les manipulations telle sorte que les indicateurs d'enregistrement ne puissent pas être facilement désactivés ou masqués. Sont en particulier décrits des indicateurs d'enregistrement qui sont intégrés dans une caméra de dispositif et qui émettent une lumière visible à travers l'ouverture de lentille de la caméra. Sont en outre décrits des accessoires modulaires que l'utilisateur doit fixer au dispositif pour permettre l'enregistrement ; la présence de l'accessoire modulaire indique à des personnes dans l'environnement qu'il est possible qu'elles soient en train d'être enregistrées.
Patent EP-4115452-A1 (EP)
Inventor: CLARKE ANDREW P
IPC: H01L31/0216
Filed: 2020-12-30
Abstract: A semiconductor device includes a substrate (12) with both a compressive layer (18) and an aluminum nitride tensile layer (16) overlying at least a portion of the substrate. The aluminum nitride tensile layer (16) is configured to counteract the compressive layer stress in the device to thereby control an amount of substrate bow in the device. The device includes a temperature-sensitive material (14) supported by the substrate, in which the temperature-sensitive material has a relatively low thermal degradation temperature. The aluminum nitride tensile layer (16) is formed at a temperature below the thermal degradation temperature of the temperature-sensitive material (14).
Patent EP-4013102-A1 (EP)
Inventor: LI JINGLAN
IPC: H04W28/24
Filed: 2020-07-06
Abstract: Provided in embodiments of the present disclosure are a cooperative channel management method and apparatus and a base station. The method includes: at a distributed unit side, a network administrator configures configuration information of cells and an activation number threshold for cooperative channels; a distributed unit control plane establishes the cells according to the configuration information, and allocates and stores identification information of the established cells; a centralized unit determines whether cells having an adjacency relationship and a cooperative relationship are located in a same distributed unit; cooperative channels between the cells having the adjacency relationship and the cooperative relationship are established according to a result of determination by the centralized unit; the distributed unit receives and accepts a cooperative relationship request established by the centralized unit for a user equipment, and transmits cooperation information using cooperative channels corresponding to the cooperative relationship. In some embodiments, it is ensured that timely and reliable transmission of cooperation information can be carried out between different cells, thus the cooperation efficiency of a lower layer of the base station can be improved and the implementations are simple and easy to carry out.