baber/WOPTO huggingface dataset:
Patent NZ-554765-A (NZ)
Title: Pegylated Liposomal Doxorubicin In Combination With Ecteinescidin 743
Inventor: GILLES ERARD
IPC: A61P35/00
Filed: 2005-10-26
Abstract: Disclosed is the use of ET-743 in the preparation of a medicament for an effective treatment of cancer of the human body by combination therapy employing an effective therapeutic amount of ET-743 with an effective therapeutic amount of Pegylated Liposomal form of the anthracycline Doxorubicin ("PLD").
Patent NZ-562500-A (NZ)
Title: Gas regulating valve that blocks a main passage but leaves communication with a leak orifice in the absence of a signal
Inventor: CHALVIGNAC PHILIPPE
IPC: A61F2/06
Filed: 2006-05-02
Abstract: Disclosed is a gas regulating valve (40) of a breathing assistance device. The breathing assistance device includes a source of pressurised respiratory gas and a gas transmission duct. The valve is interposed in the duct between the source of gas and the patient. The valve is adapted to block gas communication between the gas source and a patient whilst allowing gas communication between the patient and a leakage orifice in the absence of a signal from a controller.
Patent NZ-568909-A (NZ)
Title: Antiviral 4-fluoro-4-methyl nucleoside prodrugs
Inventor: CHUN BYOUNG-KWON
IPC: C07H19/06
Filed: 2006-11-29
Abstract: Disclosed herein is a 4-fluoro-4-mehtyl nucleoside compound of formula I, wherein R1 is selected from the group consisting of C2-5 unbranched or branched alkyl, C2-5 unbranched or branched alkenyl, C2-5 unbranched or branched alkynyl, C2-5 lower haloalkyl, C3-6 cycloalkyl and C2-4 alkoxy and hydrates, solvates and acid addition salts thereof. Also disclosed are processes for their preparation, compositions comprising said compounds, and uses for the treatment of a disease mediated by the Hepatitis C Virus (HCV)
Patent NZ-571379-A (NZ)
Title: Data input method
Inventor: KALIKI SATYA
IPC: G06F19/00
Filed: 2007-03-19
Abstract: A computer implemented method of presenting information indicating a quantity of data held in a healthcare data system relating to a patient is disclosed. The method comprises processing healthcare data associated with the patient to select one of a predetermined set of classes associated with the patient and displaying data indicating the selected class associated with the patient. Each class represents a range of numbers of data items associated with a patient. The processing comprises: querying a plurality of database tables in the healthcare data system to identify data items associated with the patient; counting the identified data items to generate a number; and selecting one of the predetermined set of classes by comparing the number with the ranges represented by the set of classes.
Patent NZ-573479-A (NZ)
Title: Matrix metalloproteinase inhibitors
Inventor: GAINES SIMON
IPC: A61K31/4035
Filed: 2004-09-10
Abstract: Disclosed is a beta hydroxy acid of formula (I) or physiologically functional derivative thereof selected from pharmaceutically acceptable esters, amides and carbamates, salts and solvates thereof wherein R1, R1' and R3 are all hydrogen, ABD is CH2-CH2, R2 is COOH, X is methylene, Y is CH(OH), Z is a bond and the other substituents are defined in the specification. Also disclosed is a composition comprising said acid, a process of preparation of said acid and a use of acid of formula (I) for the manufacture of a medicament for the treatment of inflammatory conditions or autoimmune disorders. (62) Divided Out of 545211
Patent NZ-573502-A (NZ)
Title: Method of applying a dispersion
Inventor: NAGEL MANFRED
IPC: A01N59/00
Filed: 2007-07-13
Abstract: Disclosed is a method of applying an insecticidally active aqueous dispersion which contains a hydrophobic silicic acid, wherein a two-substance nozzle is used and the insecticide aqueous dispersion is finely atomized.
Patent NZ-575858-A (NZ)
Title: Blood vessel prosthesis and delivery apparatus
Inventor: ROTHMAN MARTIN TERRY
IPC: A61F2/06
Filed: 2007-08-30
Abstract: A prosthesis 3 suitable for delivering to the branch region of the ascending aorta 11 and the right and left coronary arteries 12, 13, comprises a main conduit 33 and first and second branch conduits 31, 32. The branch conduits 31, 32 are for locating in the right and left coronary arteries 12, 13 respectively upon moving from a first position in which they are located in the main conduit 33 to a second position in which they project out from the main conduit 33. The branch conduits 31, 32 turn inside out as they move from the first position to the second position. The prosthesis is delivered to the branching site on a pair of guide wires that are inserted percutaneously through the descending aorta and into the left and right coronary arteries respectively. The prosthesis may be held in place by expanding stents and the main body may be constructed from an expanding shape memory alloy that is held compactly within a delivery casing 4 whilst being delivered to the site then pushed out of the casing by push rods 53, 51, 52. Once the prosthesis is in place the delivery casing, push rods, and the guide wires are withdrawn from the site.
Patent NZ-592107-A (NZ)
Title: Sheeting with composite images that float and method of forming
Inventor: LORIMOR LYNN E
IPC: B44F7/00
Filed: 2009-10-15
Abstract: 592107 Microlens sheetings with different types of composite images are disclosed, in which the composite image floats above, in, or below the sheeting, or some combination. One type of composite image may be viewable to the unaided eye or an observer and another type of composite image is viewable only to the aided eye of an observer. The sheeting comprises an array of microlenses; a material layer adjacent the array of microlenses; and a first donor material in contact with the material layer. The donor material forms at least two individual, partially complete images on the material layer associated with each of a plurality of the microlenses. A first composite image is provided by at least one of the individual images appears to the unaided eye to float above or below the sheeting, or both. A second composite image provided by at least one of the individual images appears to the aided eye to float above, in, or below the sheeting, or any combination thereof. The second composite image is aligned with the first composite image and includes micrographics.
Patent NZ-595972-A (NZ)
Title: Method for improving the dissolution profile of a biologically active material
Inventor: MEISER FELIX
IPC: A61K31/405
Filed: 2010-04-23
Abstract: IP No. 595972 The present disclosure relates to a method for improving the dissolution profile of a biologically active material, comprising: dry milling a solid biologically active material and a millable grinding matrix (one of lactose anhydrous, lactose monohydrate and mannitol) in a mill comprising a plurality of milling bodies, for a time period sufficient to produce particles of the biologically active material dispersed in an at least partially milled grinding matrix, wherein the particles have an average particle size of 1–200 μm determined on a particle number basis or particle volume basis, wherein the average particle size of the biologically active material has been reduced by less than 70% during dry milling and the dissolution of the biologically active material is improved such that a dissolution concentration of X is achieved in 10-30 minutes and X is the concentration equal to the dissolution concentration of the biologically active material prior to dry milling after 60 minutes, wherein the solid biologically active compound and the millable grinding matrix are milled with a facilitating agent, wherein the time period sufficient is a range selected between 5 minutes and 8 hours, wherein the milling bodies are balls having a diameter between 1mm and 20 mm, and wherein the biologically active material is selected from the group consisting of: anti-obesity drugs, central nervous system stimulants, carotenoids, corticosteroids, elastase inhibitors, anti-fungals, oncology therapies, antiemetics, analgesics, cardiovascular agents, anti-inflammatory agents, such as NSAIDs and COX-2 inhibitors, anthelmintics, anti-arrhythmic agents, antibiotics, penicillins, anticoagulants, antidepressants, antidiabetic agents, antiepileptics, antihistamines, antihypertensive agents, antimuscarinic agents, antimycobacterial agents, antineoplastic agents, immunosuppressants, antithyroid agents, antiviral agents, anxiolytics, sedatives (hypnotics andneuroleptics), astringents, alpha-adrenergic receptor blocking agents, betaadrenoceptor blocking agents, blood products and substitutes, cardiac inotropic agents, contrast media, cough suppressants, expectorants, mucolytics, diagnostic agents, diagnostic imaging agents, diuretics, dopaminergics, anti-parkinsonian agents, haemostatics, immunological agents, lipid regulating agents, muscle relaxants, parasympathomimetics, parathyroid calcitonin and biphosphonates, prostaglandins, radiopharmaceuticals, sex hormones, steroids, anti-allergic agents, stimulants and anoretics, sympathomimetics, thyroid agents, vasodilators, and xanthines. And compositions prepared by such methods
Patent NZ-598228-A (NZ)
Title: Mechanism for absorbing kinetic energy in shock absorbers and barrier ends for roadways
Inventor: AMENGUAL PERICAS ANTONIO
IPC: E01F15/00
Filed: 2010-08-20
Abstract: 598228 Disclosed is a mechanism for absorbing kinetic energy in shock absorbers and barrier ends for roadways. The mechanism comprises a deformable metallic profile (2) and a ram (1). The deformable metallic profile has an open section in the form of a ‘U’, ‘C’, ‘Omega’ or ‘Sigma’, and is indirectly secured to the ground. The ram is attached directly or indirectly to a structural element, which is capable of being displaced longitudinally as a consequence of the impact of a vehicle and producing plastic deformations propagated along the deformable metallic profile as the ram is longitudinally displaced along the deformable metallic profile. The ram comprises a base plate (10), a core (8) joined to the base plate, whose forward part has the form of a wedge with two attack surfaces (11), two wings (9) joined to the upper and lower part of the base plate and in front of the core. Two openings (12) are left between the wings and the core. The wings embrace the metallic deformable profile at a height higher than the height of the wedge-shaped part of the core, but less than the back part of the core.
Patent NZ-599144-A (NZ)
Title: Interleukin -13 binding proteins
Inventor: WU CHENGBIN
IPC: C07H21/00
Filed: 2007-09-07
Abstract: 599144 Disclosed is a binding protein that possesses an antigen binding domain, said binding protein capable of binding IL-13, said antigen binding domain comprising six CDRs: CDR-H1 (TSDMGVD), CDR-H2 (HIWWDDVKRYNPALKS), CDR-H3 (TVSSGYIYYAMDY), CDR-L1 (RASQDIRNYLN), CDR-L2 (YTSKLHS or YTSMKPR), and CDR-L3 (QQGNTLPLT or QQGLTPPLT).
Patent NZ-606204-A (NZ)
Title: Method and Apparatus for Accumulating a Jackpot Amount
Inventor: DEAN WRIGHT
IPC: A63F13/30
Filed: 2013-01-24
Abstract: The preferred method of accumulating a jackpot amount includes the step 10 of initializing a variable representing the jackpot amount and the step 11 of initializing a variable representing a lump sum. At step 12 a signal including data indicative of gaming activity is received by the controller 2, which calculates first and second increments in dependence upon said data at steps 13 and 14. The jackpot amount is incremented by the first increment at step 13 and, in response to a trigger, the jackpot amount is incremented by the lump sum at step 16. This provides a method of accumulating a jackpot amount that is volatile, unpredictable and exciting for the players of the linked jackpot game.
Patent NZ-609527-A (NZ)
Title: N1/n2-lactam acetyl-coa carboxylase inhibitors
Inventor: BAGLEY SCOTT WILLIAM
IPC: C07D519/00
Filed: 2011-10-18
Abstract: ABSTRACT - 609527 Disclosed herein is a substituted pyrazolospiroketone compound of formula (I) that act as inhibitors of an acetyl-CoA carboxylase(s), wherein the variables are as defined in the specification. These compounds are suitable for treating diseases, conditions or disorders modulated by the inhibition of acetyl-CoA carboxylase enzyme(s) and they can be used for treating Type 2 diabetes, diabetes-related disorders, non-alcoholic fatty liver disease (NAFLD) or hepatic insulin resistance.
Patent NZ-615974-A (NZ)
Title: Ipn vaccine
Inventor: EVENSEN ØYSTEIN
IPC: A61K39/12
Filed: 2012-03-14
Abstract: Disclosed is a live avirulent IPNV (Infectious pancreatic necrosis virus) which do not revert to a virulent virus after at least 3 passages in hosts known to be susceptible to IPNV; said virus comprising a nucleic acid encoding a mature VP2 protein or a precursor VP2 protein, wherein amino acid residues in position 252, 281, 282 and 319 of the protein are Asn, Ser, Asp and Glu respectively.
Patent NZ-620294-A (NZ)
Title: Apparatus, method and system for securing a strand to a post
Inventor: TAYLOR BRAD
IPC: E01F9/669
Filed: 2012-09-21
Abstract: Disclosed are an apparatus, system and method for securing a metal wire or electric cable or ribbon or tape to a fence post with a T or Y section. A portion of the post surface may be deformed to facilitate mounting of the apparatus thereto. The apparatus, when attached to the post, enables various items to be secured at the post such as strands such as fence wire, wire grid or mesh, signage, panels, etc. The apparatus comprises projections that extend from a body, to define a recess therebetween. The recess is configured to receive a post flange therein. At least one of the projections comprises an element that is configured to deflect, relative to the projection, during mounting of the apparatus to the flange to allow the flange to be received in the recess. Once the flange has been received in the recess, the element deflects back and interacts with the deformed surface portion of the post to attach the apparatus to the post. At least one of the projections is also configured to be deflected to enable the post part to be received in the recess during mounting of the apparatus to the post part. The deformation may be an indentation in the post surface, or an aperture through the surface.
Patent NZ-627444-A (NZ)
Title: Electronic cigarette
Inventor: TUCKER CHRISTOPHER S
IPC: A61M15/06
Filed: 2013-01-31
Abstract: An electronic smoking article that includes a liquid supply which is heated on a wick to a temperature sufficient to vaporize the liquid material and form an vapour. The article has a gasket in the flow path that slows the vapour down and at least two diverging outlet passages (24) in a mouth piece (8). These passages distribute vapour throughout a mouth of a smoker during a puff so as to provide a full mouth feel since the flow of vapour exits the mouth piece in different directions.
Patent NZ-702334-A (NZ)
Title: New diazaspirocycloalkane and azaspirocycloalkane
Inventor: PRUNOTTO MARCO
IPC: C07D487/10
Filed: 2013-06-10
Abstract: The invention provides novel compounds having the general formula I, wherein R1, R2, Y and W are as described herein, compositions including the compounds and methods of using the compounds. The compounds are useful in the treatment or prophylaxis of conditions that are associated with the activity of autotaxin and/or lysophosphatidic acid, such as renal, liver and inflammatory conditions, conditions of the nervous system, fibrotic diseases, and acute and chronic organ transplant rejection.
Patent NZ-712802-A (NZ)
Title: Novel n-acyl-(3-substituted)-(8-substituted)-5,6-dihydro- [1,2,4]triazolo[4,3-a]pyrazines as selective nk-3 receptor antagonists, pharmaceutical composition, methods for use in nk-3 receptor-mediated disorders
Inventor: HOVEYDA HAMID
IPC: C07D487/04
Filed: 2014-03-28
Abstract: The present invention relates to compounds of Formula I, which are novel N-acyl-(3-substituted)-(8-substituted)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazines and their pharmaceutically acceptable solvates. The compounds of Formula I are selective antagonists to neurokinin-3 receptor (NK-3) and are useful as therapeutic compounds. The present invention also relates to pharmaceutical compositions comprising a compound of Formula I or a pharmaceutically acceptable solvate thereof, and at least one pharmaceutically acceptable carrier, diluent, excipient and/or adjuvant. The present invention also relates to the use of the compounds of Formula I in the manufacture of a medicament for use in treating and/or preventing various conditions, including hot flashes, or for use as a lowering agent of the circulating luteinizing hormone (LH) levels.
Patent NZ-714298-A (NZ)
Title: Rotary blade sharpness testing device
Inventor: PETER CHRISTOPHER DOWD
IPC: B26D7/27
Filed: 2014-11-18
Abstract: An annular blade sharpness tester is provided. When knives are used the blade sharpness decreases over time. While blades can be sharpened periodically, it is more efficient to test whether a blade needs to be sharpened before sharpening the blade. The tester comprises a blade holder (2), supporting means (10) for a cuttable strip material either side of a gap, and a moving mechanism (7, 8) that causes relative movement between the holder and the supporting means, and hence the material supported by the supporting means. The tester also comprises an activation means (28) that activates a blade (27) and causes rotation of the blade before it comes into contact with the strip material, and also causes movement between the holder and supporting means so the blade movably contacts the strip material and cuts it at the gap. The tester also comprises force measuring means that measures the force of the blade on the strip material.
Patent NZ-716465-A (NZ)
Title: Anchor bolt
Inventor: ANDOU KAZUAKI
IPC: F16B13/06
Filed: 2014-01-24
Abstract: Known anchor bolts can have several drawbacks. Firstly, the shell is disposed only at a tip of the rod and the anchor bolt is fixed to, for example, a rock wall only by one shell. Further, there is a gap between the shell and the inner peripheral surface of the bore when the anchor bolt is inserted into the bore, when the rod is turned, the cone member and the shell follow the rod to be turned and the shell cannot be properly pressed by the peripheral surface of the cone member. Finally, the stress of the cone member can make the peripheral surface of the tip of the cone member difficult to properly contact the inner peripheral surface of the shell and the shell cannot be sufficiently pressed toward the inner peripheral surface of the bore by the cone member. Thus, for these reasons, the anchor bolt may not be sufficiently fixed to the wall. The present invention provides an anchor bolt fixed in a bore provided in a wall surface, comprising: a cylindrical rod having on its outer peripheral surface an external thread, and an expandable device disposed on the rod for fixing the anchor bolt on an inner peripheral surface of the bore; wherein the expandable device has a taper member and an expandable member fitted over the taper member, the taper member having an internal thread formed along a central axis of the taper member for being threadably engaged with the external thread of the rod and a plurality of planar inclined surfaces of an outer peripheral surface of the taper member, wherein the expandable member has a plurality of abutment parts and a bridge connecting tips of the abutment parts with each other, the abutment part having a planar inner surface which can surface-contact the inclined surface of the taper member , wherein each inclined surface of the taper member is inclined so as to go away from the central axis of the taper member toward a tip of the anchor bolt, wherein the tip of the taper member has a tip peripheral surface which is located adjacent to and on the tip side of the inclined surface and is formed as an upright surface along the central axis of the taper member, and wherein when the taper member is moved toward a base end of the bore in a state in which the anchor bolt is inserted into the bore, the inclined surface of the taper member is surface-pressed against the inner surface of the abutment part and an outer peripheral surface of the abutment part is pressed against the inner peripheral surface of the bore, and a portion of the inner surface of the abutment part is located closer to the tip of the anchor bolt than the inclined surface of the taper member.
Patent NZ-741954-A (NZ)
Title: Novel generation of antigen-specific tcrs
Inventor: SCHENDEL DOLORES
IPC: C12N5/0783
Filed: 2016-12-22
Abstract: The present invention contemplates methods for the generation of human antigen-specific T lymphocytes. The methods employ MHC class-II targeting signals fused to an antigen or fragment thereof to obtain MHC class presentation of RNA coded proteins. Accordingly, the present invention concerns expression vectors comprising MHC class-II targeting signal and at least one antigen or fragment thereof and its use for the in vitro generation of antigen-specific T lymphocytes. T cell clones and T cell receptors (TCRs) specific for tumor antigens or viral antigens are also described.
Patent NZ-751531-A (NZ)
Title: Microfluidic device
Inventor: HINGWING KYLA ROSE
IPC: G01N33/543
Filed: 2017-09-30
Abstract: The present disclosure provides, in part, a microfluidic apparatus for detecting target molecules. More specifically, the present disclosure relates to a protein microarray- integrated microfluidic system for detecting target molecules. The apparatus claimed comprises a wet cartridge, a dry cartridge and a protein microarray, for detecting multiple target molecules in parallel from a small volume of sample. The dry cartridge is positioned above the wet cartridge and the reagent and buffer fluid in the reservoirs of the wet cartridge are pushed up against gravity into the channels of the dry cartridge and onto the protein microarray. The channels are configured to allow for smooth flow of fluids and minimization of cross-contamination.
Patent NZ-755269-A (NZ)
Title: Virtual and augmented reality systems and methods
Inventor: SCHOWENGERDT BRIAN
IPC: H04J14/00
Filed: 2014-11-27
Abstract: Disclosed is a system for displaying virtual content. The system comprises a camera system to capture a view of a real environment, an optical see-through system and a light intensity module. The optical see-through system displays one or more virtual objects superimposed over the view of the real environment. The captured view is used to render the one or more virtual objects presented to the user. The light intensity module is configured to modulate a light intensity of the captured view, wherein the intensity is based at least on a correlation between one or more real objects and the one or more virtual objects, such that the one or more virtual objects are darker in contrast with the one or more real objects.
Patent NZ-761252-A (NZ)
Title: Passive care control method and associated systems
Inventor: CUMMINGS STEPHEN JOHN
IPC: G08B3/10
Filed: 2018-08-15
Abstract: A method for detecting abnormal usage of a physical consumable in a physical consumable usage environment (107), wherein the method comprises the steps of: monitoring detected usage data associated with the provision of at least one physical consumable in a physical consumable usage environment (107) using at least one physical consumable provisioning device (101, 103, 105) that is arranged to provide the physical consumable; and detecting abnormal usage of the physical consumable based on the monitoring of the detected usage data.
Patent PT-102779-A (PT)
Title: Textile materials pretreatment based whiteness enhancement consists of oxidative bleaching with peroxide after treatment with laccases
Inventor: PAULO ARTUR CAVACO
IPC: D06L4/40
Filed: 2002-05-17
Abstract: The textile materials pretreatment based whiteness enhancement comprises an economical technique employing oxidative bleaching of the cellulose fibres by peroxide, after treatment with laccases. This gives superior effects compared with two successive peroxide treatments.