baber/WOPTO huggingface dataset:
Patent AU-2020273314-B2 (AU)
Title: Mono- or di-substituted indole derivatives as dengue viral replication inhibitors
Inventor: KESTELEYN BART RUDOLF ROMANIE
IPC: C07D209/04
Filed: 2020-11-19
Granted: 2021-10-21
Abstract: The present invention relates to mono- or di-substituted indole compounds, methods 
to prevent or treat dengue viral infections by using said compounds and also relates 
to said compounds for use as a medicine, more preferably for use as a medicine to 
5 treat or prevent dengue viral infections. The present invention furthermore relates to 
pharmaceutical compositions or combination preparations of the compounds, to the 
compositions or preparations for use as a medicine, more preferably for the 
prevention or treatment of dengue viral infections. The invention also relates to 
processes for preparation of the compounds.
Patent AU-2020273352-B2 (AU)
Title: Handwriting keyboard for small screens
Inventor: DIXON RYAN S
IPC: G06F3/0354
Filed: 2020-11-20
Granted: 2022-06-09
Abstract: The present disclosure generally relates to handwriting on touch sensitive surfaces. In some 
examples, text suggestions strokes entered on a touch sensitive surface are viewed and selected 
in response to a rotatable input mechanism. In some examples, text determined from a set of 
strokes on the touch sensitive surface is revised based on a subsequently entered stroke on the 
touch sensitive surface. In some examples, a determination is made whether to include a stroke 
in a set of strokes based a time between the stroke and the previous stroke. In some examples, 
determining text based on a set of stroke is interrupted to determined revised text based on the 
set of strokes and a second stroke.
Patent AU-2020299635-B2 (AU)
Title: Sports mouthguard carry case
Inventor: PLAKOTARIS STEPHEN
IPC: A63B71/00
Filed: 2020-06-10
Granted: 2021-05-20
Abstract: A mouthguard carry case (10) comprising: an outer shell (12) having a hollow interior defined by an open top, an open bottom and a plurality of side walls (14). The mouthguard carry case (10) also comprises an inner shell (18) having a hollow interior defined by a top wall (20), a bottom wall (22) and plurality of side walls (24). The inner shell (18) is slidably received within the hollow interior of the outer shell (12) and is movable between an open position, and a closed position. Advantageously the mouthguard carry case (10) can be opened and closed in one hand, and is fully ventilated to promote drying and inhibit the growth of oral bacteria.
Patent AU-2020331561-B2 (AU)
Title: "Living" radical polymerization method for vinyl monomer by near-infrared photothermal conversion
Inventor: ZHANG LIFEN
IPC: C08K5/16
Filed: 2020-01-08
Granted: 2023-02-02
Abstract: The present invention provides a "living" radical polymerization method 
for a vinyl monomer by near-infrared photothermal conversion. The method 
comprises irradiating a reactor with near-infrared light of 750-850 nm, 
wherein the reactor has a first chamber and a second chamber that are 
isolated from each other, the first chamber contains an organic solution of a 
near-infrared light responsive croconaine dye, and the second chamber is 
provided with a closed reaction flask containing a reaction solution, the 
reaction solution comprises a vinyl monomer, two or more of an ATRP 
initiator, an ATRP ligand, an ATRP catalyst, an RAFT reagent, a thermal 
initiator, and an additive, and an organic solvent; and the near-infrared 
light responsive dye converts the near-infrared light into heat energy, by 
which the reactor is heated to 50-100°C to polymerize the monomer in the 
reaction solution, to obtain polymers with controlled molecular weights and 
molecular weight distributions.
Patent AU-2020357566-B2 (AU)
Title: Electric motor with enhanced thermal characteristics
Inventor: DOBMEIER JOSEPH L
IPC: H02K3/32
Filed: 2020-07-07
Granted: 2023-04-27
Abstract: An example stator of an electric motor includes a lamination stack comprising a plurality of segments (600) disposed adjacent to each other in a radial array; a slot formed in a segment of the plurality of segments of the lamination stack; a slot liner (606) disposed in the slot and configured to be electrically-insulating; a thermally- conductive gap filler (1000) disposed in a gap (800) between the slot liner and the segment; and wire windings disposed in the slot.
Patent AU-2021269438-B2 (AU)
Title: Separator-supporting bracket, basket, and portable refrigerator
Inventor: HORINAKA HIROFUMI
IPC: F25D23/08
Filed: 2021-11-19
Granted: 2023-02-16
Abstract: SEPARATOR-SUPPORTING BRACKET, BASKET, AND PORTABLE 
REFRIGERATOR 
ABSTRACT 
To provide a separator-supporting bracket that can easily support a separator in an 
existing basket.  
In a separator-supporting bracket 1 for supporting a separator 30 on a basket 20 equipped 
with a plurality of vertical wires 21 and lateral wires 22, the separator 30 partitioning an interior 
of the basket 20, a first groove 2 in an up-and-down direction being formed in an outer face of 
the bracket 1, one of the vertical wires 21 of the basket 20 passing through the first groove 2, 
and a second groove 3 in the up-and-down direction being formed in an inner face of the bracket 
1, an edge in a width direction of the separator 30 being inserted into the second groove 3. A 
retaining part 4 is provided on the separator-supporting bracket 1, the retaining part 4 being 
insertion-retained (latched) on the lateral wire 22 of the basket 20.  
FIG. 5
5/19 
21 :T 
2 
A 
3 
4 ,.-- -
4 4 B 
r --- --- 
4b A 4b 
OUTER FACE SIDE 
INNER FACE SIDE
Patent AU-2021273532-B2 (AU)
Title: Pharmaceutical combinations for the treatment of cancer
Inventor: KLINGHOFFER RICHARD
IPC: A61K31/353
Filed: 2021-11-23
Granted: 2024-02-01
Abstract: WO 2017/172826 PCT/US2017/024618 
ABSTRACT 
The disclosure herein provides combination therapies for the treatment of cancers such as 
Leukemia, lymphoma and triple negative breast cancer. The disclosure provides combination 
therapies of CDK inhibitors, e.g., a CDK inhibitor represented by Formula (I): or a 
pharmaceutically acceptable salt thereof together with a BCL-2 inhibitor or proteasome 
inhibitor for the treatment of cancer.
Patent JP-3653452-B2 (JP)
IPC: H01L25/18
Filed: 2000-07-31
Granted: 2005-05-25
Abstract: PROBLEM TO BE SOLVED: To improve productivity, to easily thin a wiring circuit board and its wiring film, furthermore, to fine and highly integrate the wiring film, or the like by providing sufficient strength even if a part that becomes a base is thin in the wiring circuit board. SOLUTION: The wiring film 22 is provided, where the wiring film 22 is made of third metal being at least different from second metal at least including a part that is connected to a bump 28 made of the first metal for composing an external terminal via an etching stop layer 21b made of the second metal as one portion. On the wiring film 22, the wiring film 25 having a bump 24 for interlayer connection that is connected to the wiring film 22 is laminated via an interlayer insulating film 27. The outermost surface of the wiring film 25 other than an electrode connection part where the electrode of the electronic device 31 is connected with an insulating film 27.
Patent JP-4729159-B2 (JP)
IPC: B25D16/00
Filed: 2000-08-10
Granted: 2011-07-20
Abstract: The combi-hammer has an actuating element (17) for an electrical on/off switch in its handle operated against a bias force, a changeover device (4) for changing between drilling and chiselling mode and a locking arrangement (5-22) for the actuating element in its on position activated by the changeover device when chiselling mode is selected. A locking switch (15) fixes the actuating element in its on position in one switch position when chiselling mode is selected and deactivates the locking device in another switch position in which the actuating element springs back into the off position under the bias force when released by the user.
Patent JP-4364425-B2 (JP)
IPC: F17C13/02
Filed: 1998-07-10
Granted: 2009-11-18
Abstract: A bulk chemical delivery system, comprising: a bulk chemical canister that is connected to at least one manifold box, wherein each manifold box has at least two output lines, wherein each output line connects to a secondary canister. In non-limiting representative example, the bulk chemical canister may have a capacity of 200 liters. Also disclosed are novel manifolds for use in delivering chemicals from canisters and a transportation/containment cart.
Patent JP-4511026-B2 (JP)
IPC: H01J37/317
Filed: 1999-01-12
Granted: 2010-07-28
Abstract: Process for writing on a material, in which said material is irradiated by means of a beam of light ions, such as for example He<SUP>+</SUP> ions, said beam of light ions having an energy of the order of or less than a hundred keV, wherein this material comprises a plurality of superposed thin-layers, at least one of said thin layers being magnetic and in that one or more regions having sizes of the order of 1 micrometer or less are irradiated, the irradiation dose being controlled so as to be a few 10<SUP>16 </SUP>ions/cm<SUP>2 </SUP>or less, the irradiation modifying the composition of atomic planes in the material at one or more interfaces between two layers of the latter.
Patent JP-4188561-B2 (JP)
IPC: C12N1/21
Filed: 1999-01-27
Granted: 2008-11-26
Abstract: The present invention provides a protein having  beta 1,4-galactosyltransferase activity, DNA encoding the protein, a recombinant DNA comprising the DNA, a transformant carrying the recombinant DNA, a process for producing  beta 1,4-galactosyltransferase by using the transformant, and a process for producing a galactose-containing carbohydrate by using the transformant.
Patent JP-4695260-B2 (JP)
IPC: A61K47/12
Filed: 1999-03-30
Granted: 2011-06-08
Abstract: Pharmaceutical dosage forms for anticancer drugs, and paclitaxel in particular, are described in which the active drug is formulated as storage stable self-emulsifying preconcentrate.
Patent JP-4685240-B2 (JP)
IPC: G01R1/073
Filed: 1999-07-08
Granted: 2011-05-18
Abstract: A multi-point electrical probe for testing location-specific electrical properties on circuit boards. Four generally parallel, electrically conducting probe arms are produced preferably by wafer-based techniques, although any even number of probe arms between two and 64 may be used. The precision of wafer-based manufacturing techniques permits miniaturization beyond that which is conventionally obtained by assembling discrete components. The probe arms are generally flexible, and may be shaped suitably to accommodate a particular circuit geometry. The probe and/or the sample under test may be precisely located by suitable translation and/or rotation stages, which may optionally be placed under computer control. A suitable wiring diagram is provided, and preferable manufacturing techniques are discussed. In addition, the conducting probe arms benefit from active guarding, which reduces leakage resistance and increases the measuring accuracy of the probe, by the inclusion of electrically-isolated conducting regions located between the probe arms.
Patent JP-4818511-B2 (JP)
IPC: C07D261/04
Filed: 1999-11-17
Granted: 2011-11-16
Abstract: A novel process for preparing the compounds of the formula Iwhere:n is 0, 1 or 2;R1, R2 are C1-C6-alkyl;R3, R4, R5 are hydrogen or C1-C6-alkyl, or R4 and R5 together form a bond;R6 is Cl, Br,which comprises a synthesis sequence starting from 1,2-dialkylbenzenes of the formula IIwith subsequent halogenation to give 3,6-dihalo-1,2-dialkylbenzenes, haloalkylation to give benzyl bromides, oxidation to give benzaldehydes, oximation, reaction with alkenes to give isoxazoles, conversion into thioethers and, if appropriate, oxidation to give sulfenyl or sulfonyl derivatives of the formula I.
Patent JP-4297617-B2 (JP)
IPC: H01C1/032
Filed: 2000-01-18
Granted: 2009-07-15
Abstract: Printed circuit boards with integral high and low value resistors are efficiently produced. The method of their manufacture entails applying a first layer of a low resistance material onto a dielectric substrate in a predetermined thickness and pattern. The pattern defines the electrical lengths and widths of low value resistors, as well as pairs of terminal electrode pads for the high value resistors. A second layer of a high resistance material is applied between and in contact with the top surfaces of the facing ends of each member of the terminal pad pairs. The fixed lengths, widths and thicknesses of the patterned high resistance material determine the values of the high value resistors. Conductive metal terminals are provided at the ends of the low value resistors and at the distal ends of the high value resistor pad pairs to complete the resistors.
Patent JP-3541181-B2 (JP)
IPC: C12N15/09
Filed: 2001-02-09
Granted: 2004-07-07
Abstract: A system for simple nucleic acid analysis is described in which the amplification space contains at least a part of the binding space. An additional improvement is achieved by the design of the binding or/and amplification space which is optionally surrounded by a heatable metal layer.
Patent JP-3550375-B2 (JP)
IPC: A47J31/02
Filed: 2001-04-16
Granted: 2004-08-04
Abstract: A filter device for coffee or the like which includes an open frame 2 formed of sheet material having predetermined rigidity, such as thick paper, and which is smaller in diameter than a blind-end frame 3. Both the frames are connected by a tubular body part 5 formed of deformable sheet material provided with shape retaining ability having predetermined rigidity and flexibility such as thin paper, non-woven fabric, etc. to compose a cup-like container body 1 having a wider bottom in a shape of substantially truncated cone. The filter device can be placed on a coffee cup for use. When the filter device is not in use, the open frame 2 is folded and pushed into the blind-end frame 3 by means of flexibility of the body part 5 and contracted. For use, the open frame 2 is pulled up to expand the body part 5, and the container body is restored into the cup-like shape and prepared to be poured with hot water. <IMAGE>
Patent JP-3842129-B2 (JP)
IPC: G06F9/38
Filed: 2000-08-30
Granted: 2006-11-08
Abstract: In the present invention, an input and/or output interface of at least one of a plurality of processing units forming a data processing system is designated independently of timing of execution of the processing unit, so as to allow the plurality of processing units to define various data paths at the program level. The present invention makes it possible to flexibly execute individual complicated data processes with hardware at a high speed without having various dedicated circuits fixed specifically to the respective data processings. <IMAGE>
Patent JP-4588959-B2 (JP)
IPC: B29C33/42
Filed: 2000-08-29
Granted: 2010-12-01
Abstract: Structured surface articles such as molds or sheeting are formed on a compound substrate including a machined substrate and a replicated substrate. In one embodiment, the structured surface is a cube corner element on a compound substrate. In another embodiment, the structured surface is a geometric structure that has a plurality of faces, where one face is located on the machined substrate and another face is located on the replicated substrate. In yet another embodiment, at least some of the faces include a compound face with a portion formed on the machined substrate and a portion formed on the replicated substrate. The method of making a structured surface article including a geometric structure having a plurality of faces includes forming an array of geometric structures in a first surface of a machined substrate; passivating selected locations of the first surface of the machined substrate; forming a replicated substrate of the machined substrate to form a compound substrate; forming an array of second geometric structures on a second surface opposite the first surface on the machined substrate; and removing selected portions from the second surface of the machined substrate.
Patent JP-4059672-B2 (JP)
IPC: C12N7/02
Filed: 2001-03-16
Granted: 2008-03-12
Abstract: The present invention features a non-human animal model that is susceptible to infection by human hepatotrophic pathogens, particularly human hepatitis C virus (HCV). The model is based on a non-human, immunocompromised transgenic animal having a human-mouse chimeric liver, where the transgene provides for expression of a urokinase-type plasminogen activator in the liver. The invention also features methods for identifying candidate therapeutic agents, e.g., agents having antiviral activity against HCV infection. The animals of the invention are also useful in assessing toxicity of various agents, as well as the activity of agents in decreasing blood lipids.
Patent JP-4987207-B2 (JP)
IPC: C08J9/04
Filed: 2001-02-13
Granted: 2012-07-25
Abstract: Macrocellular polyolefin foams that can withstand temperatures above 110° C. are described for use in sound absorption and insulation applications, especially in elevated temperature and/or moist environments. These foams have a large cell size (>=1.5 mm), are open or closed-cell foams, and preferably have at least one perforation per square centimeter and/or a density less than 25 kg/m3. They are obtainable by extruding a high melt strength (HMS) polypropylene resin (PP), or preferably a blend of a HMS PP resin and a free radical polymerized ethylene polymer present in the blend in a weight ratio of at least 35:65, optionally another polymer such as a substantially random interpolymer, a cell size enlarging agent such a glycerol monostearate, an antioxidant, carbon black and/or flame retardant additives, using a volatile organic compound, e.g. isobutane, as blowing agent.
Patent JP-4210454-B2 (JP)
IPC: C07K16/28
Filed: 2002-01-29
Granted: 2009-01-21
Abstract: Antibodies against AILIM (also called ICOS and 8F4). were found to significantly suppress the onset of inflammatory bowel diseases (especially Crohn's disease and colitis (ulcerative colitis and such)), and exhibit a significant therapeutic effect against inflammatory bowel diseases.
Patent JP-3876781-B2 (JP)
IPC: G10L19/16
Filed: 2002-07-16
Granted: 2007-02-07
Abstract: The present invention relates to a transmitting apparatus, a transmitting method, a receiving apparatus, a receiving method, a transceiver, a communication apparatus and method, a recording medium, and a program in which high quality voice can be decoded. A cellular telephone 421-1 outputs coded voice data and also supplies uncoded voice sample data to a switching center 423 while a telephone call is not made. Based on voice data used for the previous calculation processing and newly input voice data, the switching center 423 performs calculation processing for quality-improving data for improving the quality of voice to be output from a cellular telephone 421-2 that receives the coded voice data. The switching center 423 stores the optimal quality-improving data as a user information database in association with the cellular telephone 421-1. The cellular telephone 421-2 decodes the coded voice data based on the optimal quality-improving data supplied from the switching center 423. The present invention can be applied to cellular telephones. <IMAGE>
Patent JP-3610972-B2 (JP)
IPC: B60L50/16
Filed: 2002-09-04
Granted: 2005-01-19
Abstract: <P>PROBLEM TO BE SOLVED: To dissolve the generated power shortage of a generator caused by the drop of a gear ratio in the case of driving a driven wheel with power generated by the generator.  <P>SOLUTION: A front wheel is driven by an engine 2 via an automatic transmission 4, a rear wheel is driven via an electromagnetic clutch 12 by a DC motor 3, and the DC motor 3 is driven with power generated by a generator 7. This driving force controller dissolves the generated power shortage of the generator 7 by reducing and compensating the objective value Ifm of a motor field current computed based on the rotational speed of a motor, thereby lowering a counter electromotive force generated in the electric motor 3, when it is detected that a reverse range at a gear ratio smaller than that at a first speed gear position in a drive range where the automatic transmission 4 comes to a maximum gear ratio is selected by a shift position sensor 25.  <P>COPYRIGHT: (C)2004,JPO
Patent JP-4955893-B2 (JP)
IPC: A61J7/04
Filed: 2001-06-23
Granted: 2012-06-20
Abstract: The object of the present invention is to provide a medicinal product package which is suitable for microbe eradication therapy and with which the patient's compliance is increased and thus the result of therapy is improved.
Patent JP-4126228-B2 (JP)
IPC: A61B19/00
Filed: 2001-10-25
Granted: 2008-07-30
Abstract: An apparatus for adjustably securing an ultrasonic transducer to an orthopedic appliance is disclosed. The apparatus having; (a) an optional adjustable clamp adapted to adjustably secure the apparatus to an element of an orthopedic appliance; (b) a transducer holder adapted to secure the transducer to the apparatus; (c) an adjustable connector adapted to adjustably connect the optional adjustable clamp to the transducer holder.
Patent JP-3629483-B2 (JP)
IPC: F16F13/26
Filed: 2001-07-16
Granted: 2005-03-16
Abstract: This invention provides a switching type liquid-in vibration isolating device capable of opening/closing an orifice by changing over between the atmospheric and negative pressure in a switching chamber corresponding to shake and idle vibration, respectively. In order to prevent a pipe, for introducing the atmospheric and negative pressure in the switching chamber, from disconnecting, a first and a second fitting 1, 2 are connected by a vibration isolating substrate 3, a partition member 4, a first and a second diaphragm 5, 6 are disposed within a hollow space thereof, a main liquid chamber 7 and a sub-liquid chamber 8 are interconnected by two inside and outside orifices 12, 13, a equilibrium chamber 9 is formed between the first and second diaphragm 5, 6, a switching chamber 10 is formed between the second diaphragm 6 and the second fitting 2, the center portion of the bottom wall 22 of the second fitting 2 is depressed toward the switching chamber 10, a pipe 11 is pierced into the top 25a of the depressed portion 25 and received in the depressed portion 25, and a plurality of convex portions 29 for interference prevention are outwardly projectively provided on the bottom wall 22 around the depressed portion 25. <IMAGE>
Patent JP-4060191-B2 (JP)
IPC: C12N15/09
Filed: 2001-09-28
Granted: 2008-03-12
Abstract: The present invention provides novel engineered derivatives of green fluorescent protein (GFP) which have an amino acid sequence which is modified by amino acid substitution compared with the amino acid sequence of wild type Green Fluorescent Protein (SEQ ID NO: 2). The modified GFPs exhibit enhanced fluorescence relative to wtGFP when expressed in non-homologous cells at temperatures above 30° C., and when excited at about 490 nm compared to the parent proteins, i.e. wtGFP. An example of a preferred protein is F64L-S175G-E222G-GFP. The modified GFPs provide a means for detecting GFP reporters in mammalian cells at lower levels of expression and/or increased sensitivity relative to wtGFP. This greatly improves the usefulness of fluorescent proteins in studying cellular functions in living cells.
Patent JP-3687916-B2 (JP)
IPC: F01N3/08
Filed: 2003-10-28
Granted: 2005-08-24
Abstract: [PROBLEMS] A vehicle-mounted SCR device in which the concentration of a reducing agent, a reducing agent contained in its precursor, or a precursor is detected accurately. [MEANS FOR SOLVING PROBLEMS] When the concentration is detected, it is judged whether urine water stored in a storage tank is in stationary state or not, and the concentration is detected only when it is in stationary state. Preferably, the judgment whether urine water is in stationary state or not is made by judging that a vehicule stops (S207) and the time TIM after the stoppage has reached a specified rest time TIM1 (S211). The decceleration DCL of the vehicle before the stoppage is detected and the rest time TIM1 is altered depending on the deceleration DCL (S206).