baber/WOPTO huggingface dataset:
Patent DE-69306106-T2 (DE)
Inventor: BUTERA JOHN
IPC: C07D405/04
Filed: 1993-05-05
Granted: 1997-04-03
Abstract: The compounds of the formula:   <IMAGE>   wherein R1 is C1-6 perfluoroalkoxy, C1-6 perfluoroalkyl, C1-6 alkyl, C1-6 alkoxy, hydroxyl, C2-6 alkoxycarbonyl, nitro, cyano, halogeno, C1-6 alkylsulfonamido, C1-6 perfluoroalkylsulfonamido, amino, C2-6 alkanoylamino, C2-6 perfluoroalkanoylamino, C1-12 mono- or di-alkylamino, C1-6 alkylsulfonyl, C6-12 arylsulfonyl, carboxyl, or C2-12 mono- or di-alkylcarbamoyl; R2 is hydrogen, C1-6 perfluoroalkoxy, C1-6 perfluoroalkyl, C1-6 alkyl, C1-6 alkoxy, hydroxyl, C2-6 alkoxycarbonyl, nitro, cyano, halogeno, C1-6 alkylsulfonamido, C1-6 perfluoroalkylsulfonamido, amino, C2-6 alkanoylamino, C2-6 perfluoroalkanoylamino, C1-12 mono- or di-alkylamino, C1-6 alkylsulfonyl, C6-12 arylsulfonyl, carboxyl, or C2-12 mono- or dialkylcarbamoyl; R3 and R4, independent from each other, are C1-6 alkyl; either R5 is hydrogen, hydroxyl, C2-6 alkanoyloxy, C7-12 aroyloxy, carbamoyloxy, formyloxy, C2-6 alkoxycarbonyloxy, C2-12 mono- or di-alkylcarbamoyloxy, and R6 is hydrogen, or R5 and R6 together are a bond; R 7 and R8, independent from each other, are selected from the following: C1-6 perfluoroalkoxy, C1-6 perfluoroalkyl, C1-6 alkyl, C1-6 alkoxy, hydroxyl, C2-6 alkoxycarbonyl, nitro, cyano, halogeno, C1-6 alkylsulfonamido, C1-6 perfluoroalkylsulfonamido, amino, C1-6 alkanoylamino, C2-6 perfluoroalkanoylamino, C1-12 mono- or di-alkylamino, C1-6 alkylsulfonyl, C6-12 arylsulfonyl, carboxyl, C2-12 mono- or di-alkylcarbamoyl, or hydrogen; and R9 is hydrogen, C1-6 alkyl, C2-6 alkylcarbonyl or C1-6 alkylsulfonyl; or a pharmaceutically acceptable salt thereof are useful as smooth muscle relaxants, as antihypertensives and K channel activators.
Patent DE-69309077-T2 (DE)
Inventor: ASAGI KOSAKU
IPC: D06M15/55
Filed: 1993-09-01
Granted: 1997-08-28
Abstract: A water-containing aromatic polyamide pulp which has been surface-treated with an epoxy resin and has a water-content of 30 to 95 % by weight. This pulp is produced by dispersing an aromatic polyamide pulp in an aqueous epoxy resin emulsion, filtering the mixture and then dehydrating the pulp separated.
Patent DE-69314560-T2 (DE)
Inventor: WESLEY JOHN N
IPC: C10L7/04
Filed: 1993-07-20
Granted: 1998-06-04
Abstract: Organic liquids can be very effectively gelled by using in combination with an amine neutralized anionic polymer an auxiliary rheological additive. The auxiliary rheological additive is a substance which increases the linearity of the anionic polymer and its thixotropic properties. Suitable auxiliary rheological additives are fatty acids and/or fatty acid salts optionally in combination with amphoteric oxides. The organic liquids that can be effectively gelled are organic solvents which include fuels such as hydrocarbons and alcohols.
Patent DE-69315320-T2 (DE)
Inventor: BELONENKO VLADIMIR NIKOLAEVICH
IPC: G01N29/00
Filed: 1993-08-12
Granted: 1998-06-10
Abstract: A device which can be used in technology for precise measurement, under diverse pressures and temperatures, of such physical properties of fluids like isothermic and adiabatic compressibility, density, coefficient of thermal expansion, speed of propagation and level of absorption of ultrasound, and for determination, on the basis of the said parameters, of heat capacity and other thermal-physical and thermodynamic properties, functions and potentials, and which comprises a casing (1) consisting of a high-pressure vessel with a measurement chamber, a piston (8), a unit (14) for generation and reception of signals and for data recording and processing, an oscillation transducer (5) mounted inside the chamber and forming two interconnecting measuring cells with a permanent (6) and a variable (7) base. Between the piston and the oscillation transducer may be mounted with a slide fit a piston insert (17). The device allows increased precision and resolving power when measuring physical properties of fluids at diverse pressures, volumes and temperatures. <IMAGE>
Patent DE-69320352-T2 (DE)
Inventor: WANNAMAKER MARION
IPC: A61P31/04
Filed: 1993-06-03
Granted: 1998-12-17
Abstract: The present invention relates to piperidyl amides which are useful as inhibitors of cholesterol biosynthesis and as agents which lower total serum cholesterol in patients in need thereof.
Patent DE-69327432-T2 (DE)
Inventor: OKUMURA MAKOTO
IPC: A61K31/5585
Filed: 1993-02-05
Granted: 2000-05-18
Abstract: A remedy for wounds or hemorrhoids, in particular, an external preparation containing at least one member selected among prostaglandin I2, prostaglandin E1 and derivatives thereof, in particular, beroprost, one of the prostaglandin I2 derivatives, or a salt thereof as the active ingredient; and a therapy for wounds or hemorrhoids characterized by administering the above active ingredient.
Patent DE-69327658-T2 (DE)
Inventor: KENNY JOHN D
IPC: G06F1/32
Filed: 1993-11-29
Granted: 2000-09-14
Abstract: A NAPNOP circuit for decreasing energy consumption of all or a portion of a microprocessor based system which includes a delay circuit for inhibiting or slowing the output of the system clock pulses for a variable length of time equal to a multiple of N clock pulses where N is a positive integer. The NAPNOP circuit has an input element for inputting a STARTNAP signal which begins a nap period during which the system clock pulses are inhibited or slowed, a clock input device for providing a plurality of selectable clock pulses as inputs to the delay circuit for controlling the operation of the computer system, and a gate element for terminating the nap period. <IMAGE>
Patent DE-69329337-T2 (DE)
Inventor: SELSTED E
IPC: A61K9/22
Filed: 1993-05-26
Granted: 2001-04-26
Abstract: The present invention provides substantially purified cryptdin peptides characterized as being cationic and between 30 and 40 amino acids in length, being found naturally in the epithelial cells of the small intestine, exhibiting specific antimicrobial activity against intestinal pathogens, and having a consensus amino acid sequence as follows: X1-C-X2-C-R-X3-C-X4-E-X5-G-X6-C-X7-C-C-X8, wherein X1 is 3-6 amino acids; X2 is one amino acid; X3 is 2 or 3 amino acids; X4 is three amino acids; X5 is three amino acids; X6 is one amino acid; X7 is 6 to 10 amino acids; and X8 is 0 to 7 amino acids. The preferred embodiments are illustrated as mouse cryptdin-1 (SEQ ID NO:9), mouse cryptdin-2 (SEQ ID NO:10), mouse cryptdin-3 (SEQ ID NO:11), mouse cryptdin-4 (SEQ ID NO:12), mouse cryptdin-5 (SEQ ID NO:13), and rat cryptdin-1 (SEQ ID NO:14). The present invention provides a method for detecting inflammatory pathologies in a subject and, further, provides a method for treating an infectious process by the administration of the cryptdin peptides in a physiologically acceptable medium.
Patent DE-69330993-T2 (DE)
Inventor: BERKOWITZ BRIAN T
IPC: G06F17/30
Filed: 1993-12-08
Granted: 2002-04-04
Abstract: A method is disclosed for recording a text index wherein the text index comprises a plurality of data key fields. Each data key field includes a data key identifier, document identifier data, and an offset field. The document identifier data is provided to identify each document in which the data key identifier appears. The offset field includes a plurality of offset sequences wherein each offset sequence is associated with a respective document identified by the document identifier data and wherein each offset sequence identifies the location of each data key within its associated document by identifying the offset of the data key from the preceding data key. In accordance with the subject invention, the document identifier data and the offset data field are compressed by disclosed methods.
Patent DE-69401132-T2 (DE)
Inventor: GOET RICHARD CLAAS
IPC: B01D27/08
Filed: 1994-01-14
Granted: 1997-06-26
Abstract: A filtration apparatus with exchangeable filters for hygienic filtration of contaminated fluids. A tubular filter housing (1) has a central bore (2) as a receiving chamber for a filter cartridge. O-shaped rings (5,6) are mounted at the ends and in the centre of the wall of the receiving chamber, and these prevent fluid from leaking around the filter. The filter housing has a fluid entrance opening (7), and, diametrically opposite to it, an exit (8) lying lower. A filter cartridge has a filter element (11) and two end caps (13 and 14). The rear end cap (13) has an annular opening (16) which is in connection with the filter chamber (12) within the filter element. In an assembled state, the fluid entrance (7) is in connection with the annular opening (16) in the filter chamber. Contaminated fluid is sucked in through entrance (7) and it proceeds through the filter to fluid exit (8). The replacement of the filter takes places by pressing in a new filter cartridge at the top of the filter housing, which causes the soiled filter to be pressed out at the underside without this needing to be contacted by hand. <IMAGE>
Patent DE-69421534-T2 (DE)
Inventor: POOLMAN GERARD CHARLES
IPC: A45D34/04
Filed: 1994-11-18
Granted: 2000-05-18
Abstract: The present invention relates to a roll-on applicator (10) which prevents leakage or spillage without the need of the cooperation of a cap. This container comprises a ball (3) and a flexible and resilient support means (4) for said ball. Said flexible and resilient support means is such to urge said ball against said dispensing opening, achieving a leak-tight engagement between said ball and said dispensing opening. Furthermore, said flexible and resilient support means can be resiliently deformed by an external force acting on said ball to disengage said leak-tight engagement between said ball and said dispensing opening, allowing said contained product to be spread by said ball. <IMAGE>
Patent DE-69424236-T2 (DE)
Inventor: NICKS TIMOTHY J
IPC: G01N21/90
Filed: 1994-09-13
Granted: 2000-11-30
Abstract: Apparatus for detecting checks in the sidewall of a translucent container (22) that includes a light source (24) for illuminating an elongated strip of the container sidewall parallel to the central axis of the container in such a way that illumination rays are incident at any point of the strip from multiple differing angles. A camera (50) is positioned externally of the container for receiving light reflected by checks in the illuminated strip, and electronic circuitry (52) is coupled to the camera for detecting checks in the container as a function of such reflected light. Since the light rays at any point in the elongated illuminated strip on the container sidewall are incident from multiple differing angles, planar checks and split seams in the container sidewall that are not precisely vertical in orientation will have a greater chance of reflecting light energy from the source onto the camera. <IMAGE>
Patent DE-69426130-T2 (DE)
Inventor: GAMBLIN ALAN
IPC: A01N43/56
Filed: 1994-05-16
Granted: 2001-03-01
Abstract: A herbicide composition comprises a mixture HERB1 (named Pyraflufen-ethyl or 1-methyl-3-(2-fluoro-4-chloro-5-(-O-CH2-C(O)-O-C2H5)-phenyl)-4-chloro- 5-difluoromethyloxypyrazole) (I) and Aclonifen (2-chloro-6-nitro-3-phenoxyaniline).
Patent DE-69430295-T2 (DE)
Inventor: DOHI MASAHIKO
IPC: A61K38/28
Filed: 1994-07-29
Granted: 2002-10-31
Abstract: A powder for nasal administration of a peptidic or proteinaceous drug comprising: (i) a sorbefacient comprising a compound having a group represented by general formula (I) in its molecule, (wherein the ring (a) represents a cyclohexane or benzene ring which may be substituted at at least 3-, 4- or 5-position; and n represents an integer of 1 to 3) or a salt thereof, and (ii) a peptidic or proteinaceous drug in a therapeutically effective dose. <CHEM>   <IMAGE>
Patent DE-69503117-T2 (DE)
Inventor: KORN STEWART
IPC: C07C63/72
Filed: 1995-02-17
Granted: 1998-10-29
Abstract: PCT No. PCT/GB95/00335 Sec. 371 Date Nov. 4, 1997 Sec. 102(e) Date Nov. 4, 1997 PCT Filed Feb. 17, 1995 PCT Pub. No. WO95/24373 PCT Pub. Date Sep. 14, 1995A process for the monodecarboxylation of a halogenated aromatic dicarboxylic acid or derivative thereof in which the halogenated aromatic dicarboxylic acid or derivative thereof in a liquid medium is heated characterized in that the liquid medium is a polar aprotic liquid medium.
Patent DE-69510680-T2 (DE)
Inventor: DANIELSSON AKE
IPC: B23C5/04
Filed: 1995-09-11
Granted: 1999-10-21
Abstract: PCT No. PCT/SE95/01016 Sec. 371 Date Mar. 20, 1997 Sec. 102(e) Date Mar. 20, 1997 PCT Filed Sep. 11, 1995 PCT Pub. No. WO96/08334 PCT Pub. Date Mar. 21, 1996A drilling tool for drilling in metals has in its front part cutting insert-carrying cartridges, for instance 3, 5 or 7 in number. The peripheral cartridge (6) carries a peripheral cutting insert (7). This peripheral cartridge is fastened in the drill by a locking screw (16) that extends in a slot (17) in the drillhead. Radially inside of the peripheral cartridge is a wedge (15) which can be displaced axially and thereby regulate the radial position of the peripheral cartridge and cutting insert and, thereby, the cutting diameter. When the desired radial adjustment has been attained, the peripheral cutting insert is fixed by the locking screw (16). In this way, a very exact adjustment of the cutting diameter is obtained.
Patent DE-69511041-T2 (DE)
Inventor: VAN LIERDE CARLOS
IPC: B61B10/02
Filed: 1995-10-17
Granted: 1999-12-30
Abstract: Device for coupling and/or uncoupling conveyor elements in relation to a driving mechanism, consisting of a rotatable element (6) in which is provided a guide (7) for a drag pin (4) of a conveyor element (2) and driving means (8) to rotate the rotatable element (6), such that a conveyor element (2), as a result of the rotation of the rotatable element (6) and by putting it in a given angular position, can be uncoupled from and/or coupled to the driving mechanism, characterized in that means (21) are provided between the driving means (8) and the rotatable element (6) which can give away when the rotatable element (6) jams. <IMAGE>
Patent DE-69511502-T2 (DE)
Inventor: DE GROOT JACOB FRANK
IPC: C09K17/48
Filed: 1995-11-07
Granted: 2000-01-05
Abstract: The invention relates to a coherent growth substrate based on a synthetic matrix containing clay in a quantity of 0.1-25% by weight such that at a suction pressure of pF=2 the moisture content is lower than 15% by volume, preferably for use as a grow-block and for a grow-slab.
Patent DE-69512289-T2 (DE)
Inventor: DELIMOY DIDIER
IPC: C08K7/02
Filed: 1995-02-15
Granted: 2000-05-11
Abstract: Thermoplastic material comprises a thermoplastic polymer(s), a reinforcing fibrous material(s) and a material which absorbs IR rays and present at 1-1000 ppm. Also claimed is the prodn. of a thermoplastic article by IR irradiating the above material.
Patent DE-69521239-T2 (DE)
Inventor: YANAGAWA MED DR
IPC: A61K9/14
Filed: 1995-04-28
Granted: 2001-09-20
Abstract: A nasally administrable composition having a physiologically active substance dispersed homogeneously in and adsorbed homogeneously onto a unique carrier. The nasally administrable composition contains a physiologically effective amount of the physiologically active substance having a molecular weight of not more than 40,000, dispersed homogeneously in and adsorbed homogeneously onto physiologically acceptable powdery or crystalline polyvalence metal compound carrier. The metal compound carrier is selected from aluminum compound, calcium compound, magnesium compound, silicon compound, iron compound and zinc compound. The composition is nasally administrable in powdery form.
Patent DE-69531356-T2 (DE)
Inventor: LANGSTON MARIANNE
IPC: C07D211/60
Filed: 1995-10-23
Granted: 2004-05-27
Abstract: PCT No. PCT/GB95/02513 Sec. 371 Date Apr. 25, 1997 Sec. 102(e) Date Apr. 25, 1997 PCT Filed Oct. 23, 1995 PCT Pub. No. WO96/12699 PCT Pub. Date May 2, 1996Levobupivacaine or an analogue thereof is prepared by reaction with a tartaric acid resolving agent in a solvent, in the presence of water and/or less 0.5 equivalents of the resolving agent.
Patent DE-69533424-T2 (DE)
Inventor: DIGICOMM LTD HONG KONG
IPC: H04W88/18
Filed: 1995-06-15
Granted: 2005-09-15
Abstract: A two-way paging system utilizes four local frequencies for transmissions between pager units (22) and a central control station (20). A first local frequency (f1) carries a local clock; a second local frequency (f2) carries communications packets from the central control station to paging units; a third local frequency (f3) carries communication packets from the pager units to the central control station; and a fourth local frequency (f4) carries a status or request signal from the paging units (22) to the central control station (20). Transmissions on the fourth local frequency (f4) are in accordance with a time divided slot allocation among pager units accessing the central control station (20). For a two-way paging system having a plurality of central control stations (420x) servicing a corresponding plurality of cells, a total of eight frequencies are utilized within any one cell. Four of the utilized frequencies are the local frequencies (f1-f4) Äwhich may differ from cell to cellÜ, and four of the utilized frequencies are lower power common frequencies or switching frequencies (C1-C4) which are used to switch or hand-off a pager unit (422) traveling from one cell to another. <IMAGE>
Patent DE-69602359-T2 (DE)
Inventor: DOWNS IAIN
IPC: G06F17/21
Filed: 1996-03-19
Granted: 1999-09-02
Abstract: PCT No. PCT/GB96/00656 Sec. 371 Date Dec. 15, 1997 Sec. 102(e) Date Dec. 15, 1997 PCT Filed Mar. 19, 1996 PCT Pub. No. WO96/29658 PCT Pub. Date Sep. 26, 1996Structured graphical data is reorganised. The data, which may be defined in accordance with portable document format (PDF) includes graphical object definitions and references to said definitions. The data is reorganised so that the graphical object references are preceded by their respective object definitions.
Patent DE-69609323-T2 (DE)
Inventor: HUMPHREY J
IPC: A61P7/10
Filed: 1996-03-11
Granted: 2000-12-14
Abstract: A diuretic compound of Formula I   <IMAGE>   or pharmaceutically acceptable salt thereof where R1 is a C1-6 alkyl; R2 is halogen, C1-4 alkyl; and R3 is C1-4 alkoxy are disclosed, preferably, benzamide, 3-chloro-N-(2-ethyl-2-(3-methoxyphenyl)-4-(1-piperidinyl)butyl), monohydrochloride. The compounds are effective diuretics which increase the excretion of water with little increase in electrolyte excretion.
Patent DE-69617340-T2 (DE)
Inventor: ABEVILLI FULVIO
IPC: C08L23/00
Filed: 1996-08-01
Granted: 2002-07-11
Abstract: A product made of synthetic plastic material composed of a thermoplastic polymer resin including at least one polymer or copolymer or a mixture of polymers or copolymers, and an inert filler dispersed uniformly in the resin, wherein the material is a foam material including a number of open or closed cells distributed substantially uniformly, and wherein the resin is cross-linked three-dimensionally. A resin, selected from the group including polyolefin and polystyrene resins and mixtures thereof, is mixed with a natural or synthetic inert filler, such as calcium carbonate, barium sulfate, etc., and with appropriate additives, is injection molded or extruded after adding chemical or physical foaming agents (inert gases), and is cross-linked, wholly or in part, by adding chemical cross-linking agents or by radiation by an electron beam.
Patent DE-69626300-T2 (DE)
Inventor: MULIER M
IPC: A61B18/14
Filed: 1996-10-02
Granted: 2003-10-16
Abstract: An electrocautery device is disclosed. In accordance with one aspect of the invention, the electrocautery electrode/tip is provided with a hollow, conductive tube terminating at its distal end in a ball point type tip. Fluid, preferably conductive fluid, is applied to the proximal end of the hollow electrode/tip, and expelled from the distal end thereof during electrocautery. The conductive fluid is supplied by a pressurized canister. The ball point distal tip allows the distal tip to be directly applied to the tissue and "rolled" or slid along the tissue. This allows the distal tip to be moved across the tissue without dragging or snagging on the tissue. In addition, the conductive fluid expelled from the distal tip further lubricates the distal tip as it moves across the tissue. If conductive fluid is used, the conductive fluid emanating from the electrode/tip conducts the RF electrocautery energy away from the distal tip so that it is primarily the fluid, rather than the distal tip that actually accomplishes the cauterizing of tissue. That is, the fluid serves as a "virtual" electrocautery electrode. Since it is the fluid, rather than the distal tip that cauterizes, coagulates and ablates, no burns or perforations are made to the tissue, reducing the amount of debris at the site. Also, the flow of fluid through the electrode/tip tends to keep the distal tip clean and cool. <IMAGE>
Patent DE-69626514-T2 (DE)
Inventor: BENETTI DINO
IPC: C07C50/18
Filed: 1996-06-17
Granted: 2003-12-24
Abstract: PCT No. PCT/EP96/02597 Sec. 371 Date Jan. 29, 1998 Sec. 102(e) Date Jan. 29, 1998 PCT Filed Jun. 17, 1996 PCT Pub. No. WO97/00675 PCT Pub. Date Jan. 9, 1997Compounds of formula (I) for treatment of pathologies in which erosion of cartilaginous and bone matrix occurs, for example osteoarthrosis. An exampliary compound is 2,6-anthraquinonesulfonamido-N,N-caproic acid.    <IMAGE>  (I)
Patent DE-69630455-T2 (DE)
Inventor: WHEATCROFT RAGINI
IPC: A23K20/163
Filed: 1996-06-28
Granted: 2004-07-22
Abstract: There is provided a method of production of an immunostimulatory beta-glucan-mannan preparation, comprising the step of autolysis of cells of a microorganism at a pH of 5 to 6 and a temperature of 35 to 60° C. for 6 to 48 hours, and separating solid material roam the autolysed product.The beta-glucan-mannan preparation may be incorporated as a food component or be used as a pharmaceutical for treatment of conditions such as immuno-suppression, hypercholesterolaemia, hypoglycaemia and heavy metal excretion.
Patent DE-69633389-T2 (DE)
Inventor: ELMORE MICHAEL JAMES
IPC: C07K1/22
Filed: 1996-06-12
Granted: 2005-10-27
Abstract: A polypeptide free of toxin activity providing protection against botulinum type F toxin is provided. A fusion protein of a fragment of a toxin molecule and a purification moiety enabling purification of a fragment from solution and pharmaceutical compositions containing the polypeptide and the fusion protein are described.
Patent DE-69636645-T2 (DE)
Inventor: RYAN ANTHONY
IPC: C07C43/12
Filed: 1996-12-06
Granted: 2007-08-23
Abstract: PCT No. PCT/GB96/03001 Sec. 371 Date Jun. 30, 1998 Sec. 102(e) Date Jun. 30, 1998 PCT Filed Dec. 6, 1996 PCT Pub. No. WO97/25303 PCT Pub. Date Jul. 17, 1997Process for producing Sevoflurane anaesthetic which comprises reacting hexafluoroisopropyl alcohol with essentially pure bis(fluoromethyl)ether. The bis(fluoromethyl)ether is preferably obtained by the reaction of formaldehyde with hydrogen fluoride.
Patent DE-69637391-T2 (DE)
Inventor: MUELLER JOHN P
IPC: G01N33/564
Filed: 1996-04-22
Granted: 2008-08-14
Abstract: Compositions and methods are provided for the clinical assessment, diagnosis, and treatment of multiple sclerosis. The compositions of the invention are molecules related to the human proteolipid protein (PLP) and/or human myelin basic protein (MBP), and include nucleic acids and polypeptides. The nucleic acid molecules of the invention are useful in the production of modified PLP polypeptides and modified MBP polypeptides, such polypeptides being useful for assaying T cells for responsiveness to PLP and MBP epitopes. The polypeptides of the invention are also useful as therapeutic agents that act by inducing T cell responses, including anergy and apoptosis, as a means of treating multiple sclerosis.