baber/WOPTO huggingface dataset:
Patent EP-3440014-A2 (EP)
Title: Capteurs à réseau de nanostructures pour détection électrochimique, détection capacitive et détection d'émission de champ
Inventor: KHALID WAQAS
IPC: H01G4/30
Filed: 2017-03-30
Abstract: La présente invention concerne l'utilisation de réseaux de nanostructures adressables individuellement en tant que nano-électrodes pour une détection électrochimique à plusieurs analytes par l'utilisation de diverses techniques de spectroscopie électrochimique, d'émission capacitive et de champ. Selon certains aspects, l'invention concerne des dispositifs et des agencements comprenant au moins deux nanostructures adressables individuellement dans un réseau sur un substrat, et leurs utilisations. Selon d'autres aspects, l'invention concerne des systèmes comprenant le dispositif et un support de puce, et comprenant en outre un matériel et un logiciel.
Patent EP-3652304-A2 (EP)
Inventor: BHOUMIK ANINDITA
IPC: A61K35/39
Filed: 2018-07-11
Abstract: Disclosed herein are universal donor stem cells and cells derived therefrom and related methods of their use and production. The universal donor stem cells disclosed herein are useful for overcoming allogeneic immune rejection in cell-based transplantation therapies. In certain embodiments, the universal donor cells disclosed herein are pancreatic endoderm cells that do not express one or more MHC-Class I cell-surface proteins and whose expression of at least one NK activating ligand is disrupted or inhibited.
Patent EP-3773708-A2 (EP)
Inventor: NABEL GARY J
IPC: C07K14/205
Filed: 2019-04-02
Abstract: La présente invention concerne des polypeptides EBV antigéniques et leur utilisation pour déclencher des anticorps contre EBV. L'invention concerne également des polypeptides antigéniques comprenant un polypeptide EBV et une protéine ferritine.
Patent EP-3814020-A2 (EP)
Inventor: FINK THOMAS
IPC: B05B13/02
Filed: 2019-06-27
Abstract: Die Erfindung betrifft eine Tragevorrichtung (2) zur Aufnahme von Rohrleitungselementen(4) in einer Oberflächenbeschichtungsanlage, mit: -einem Grundkörper (6), -einem an dem Grundkörper (6) ausgebildeten Kopplungsabschnitt (28) zur Kopplung der Tragevorrichtung (2) mit einem deckenseitigen Fördermechanismus, und -mehreren, sich seitlich von dem Grundkörper (6) aus erstreckenden Auslegern (8), dadurch gekennzeichnet, dass an jedem Ausleger (8) eine Aufnahme (10) mit paarweise angeordneten und zueinander beabstandeten Stützfüßen (12, 12´) angeordnet ist, wobei die Stützfüße (12, 12´) dazu eingerichtet sind, mit jeweils einem äußeren Wandabschnitt eines Rohrleitungselements (14) in Kontakt zu treten, um das Rohrleitungselement (4) zwischen den Stützfüßen (12, 12´) zu halten.
Patent EP-3752194-A2 (EP)
Inventor: KRIEG ARTHUR
IPC: A61P35/00
Filed: 2019-02-12
Abstract: Provided are compositions and methods for treating cancer using administration of certain volumes of CpG oligonucleotides (CpG ODN) and, optionally, administration of a checkpoint inhibitor such as an anti-PD-1 antibody, an anti-PD-Ll antibody, and/or an anti- CTLA-4 antibody. In preferred embodiments, the CpG ODN are selected based on their propensity to induce high amounts of interferon alpha (IFN-a) and T-cell activation relative to interleukin-10 (IL-10) and B-cell activation. In certain embodiments, the methods further include pretreatment with radiotherapy, to potentiate the combination immunotherapy.
Patent EP-3823963-A2 (EP)
Inventor: FU PENG
IPC: C07D401/06
Filed: 2019-07-15
Abstract: The present invention relates to a method of synthesizing a compound of formula (I) also referred to as 4-((2S,4S)-(4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl))benzoic acid, or a pharmaceutically acceptable salt thereof, and/or intermediates thereof, their use as pharmaceuticals and pharmaceutical compositions and the use of intermediates for preparing a compound of formula (I), or a pharmaceutically acceptable salt thereof.
Patent EP-3873935-A2 (EP)
Inventor: FRENDÉUS BJÖRN
IPC: A61P31/00
Filed: 2019-11-01
Abstract: L'invention concerne de nouvelles molécules d'anticorps qui se lient spécifiquement au TNFR2 sur une cellule cible et ainsi agonisent le TNFR2, mais qui n'empêchent pas le ligand TNF-α de se lier au TNFR2. L'invention concerne également l'utilisation de ces molécules d'anticorps en médecine, entre autres, dans le traitement du cancer ou de maladies inflammatoires chroniques.
Patent EP-3901305-A2 (EP)
Title: High-strength structural steel having excellent cold bendability, and manufacturing method therefor
Inventor: CHO JAE-YOUNG
IPC: C22C38/18
Filed: 2019-12-06
Abstract: A high-strength structural steel having excellent cold bendability, according to one embodiment of the present invention, comprises, by wt%, 0.02-0.1% of C, 0.01-0.6% of Si, 1.7-2.5% of Mn, 0.005-0.5% of Al, 0.02% or less of P, 0.01% or less of S, 0.0015-0.015% of N, and the balance of Fe and other inevitable impurities, wherein an outer surface layer part and an inner central part thereof are microstructurally divided in a thickness direction, the surface layer part can comprise tempered austenite as a matrix structure, and the central part can comprise bainitic ferrite as a matrix structure.
Patent EP-3713081-A2 (EP)
Inventor: BAKEER HANY GAMAL ELDIN MOHAMED
IPC: H04B17/12
Filed: 2020-03-10
Abstract: Systems and methods for providing phase shifting in antenna arrays (110), such as phased antenna arrays of 5G cellular technology, are disclosed. In one aspect, an example phase shift module (150) may include a phase shifter and a frequency multiplier. The phase shifter is configured to receive a local oscillator, LO, signal and output a signal that is phase-shifted by a desired phase shift with respect to the LO signal. The frequency multiplier may be an enhanced frequency multiplier, configured to use not only the phase-shifted signal but also an inverted version of the phase-shifted signal to generate a frequency-multiplied signal having a frequency that is a multiple of the LO signal frequency. In another aspect, an example phase shift module may be configured to apply to an LO signal a phase shift that takes into consideration variations of phase shift over temperature.
Patent EP-3741852-A2 (EP)
Title: Preparation of libraries of protein variants expressed in eukaryotic cells and use for selecting binding molecules
Inventor: MCCAFFERTY JOHN
IPC: C12N15/10
Filed: 2015-05-01
Abstract: The invention relates to methods of producing eukaryotic cell libraries encoding a repertoire of binding molecules ("binders"), wherein the methods use a site-specific nuclease for targeted cleavage of cellular DNA to enhance integration of binder genes through endogenous cellular repair mechanisms. Populations of eukaryotic cells are produced in which a repertoire of genes encoding binders are integrated into a desired locus in cellular DNA (e.g., a genomic locus) allowing expression of the encoded binding molecule, thereby creating a population of cells expressing different binders.
Patent EP-3713359-A2 (EP)
Inventor: HU BINGSHAN
IPC: H04W72/12
Filed: 2016-10-24
Abstract: The present disclosure provides base station-side and user equipment-side apparatuses and methods, and a wireless communication system, for use in wireless communication. The base station-side apparatus for use in wireless communication comprises: a setting unit, configured to set different priority levels for using uplink transmission resources on unauthorized band with respect a plurality of user equipment; and a generating unit, configured to generate an uplink scheduling authorization for using one same uplink transmission resource on the unauthorized band with respect to each user equipment, wherein each uplink scheduling authorization comprises information about a priority level of the corresponding user equipment.
Patent EP-3745092-A2 (EP)
Inventor: ROCHWERGER RICHARD
IPC: H03K17/94
Filed: 2020-05-29
Abstract: A proximity sensor bar (12) can be configured to sense or detect the presence or absence of objects on a conveyor system. The proximity bar (12) can implement multiple sensor blocks for such sensing with each sensor block including one or more electronic proximity sensors (52) and with each sensor block being spaced a predetermined distance or interval apart from one another along the bar. The proximity bar (12) comprises a circuit board (30) having a connector to connect to another circuit board and an enclosure (22) to receive the circuit board (30). The proximity bar can be used on conveyor systems, such as roller conveyors in an object movement and distribution environment, with the proximity bar spanning the width of the conveyor. In such systems, the proximity bar could be mounted between adjacent rollers or below such rollers. The proximity bar can also be used on other conveyor systems, such as belted conveyors, by mounting the proximity bar above the conveyor.
Patent EP-4041089-A2 (EP)
Inventor: MANIAN SURESH RENGANATHAN
IPC: A61B8/12
Filed: 2020-10-06
Abstract: La présente invention concerne un cathéter d'imagerie intraluminal comprenant : un élément allongé flexible conçu pour être positionné à l'intérieur d'une lumière corporelle d'un patient ; un réseau de transducteurs ultrasonores couplé à l'élément allongé flexible et configurés pour obtenir des données d'imagerie tout en étant positionnés à l'intérieur de la lumière corporelle ; et une mémoire comprenant une pluralité de régions configurées pour stocker une ou plusieurs valeurs d'un ou plusieurs champs, la pluralité de régions comprenant une première région, le ou les champs dans la première région comprenant au niveau d'une identification de dispositif, un numéro de série, et/ou une date de fabrication, la pluralité de régions comprenant au moins une seconde région, le ou les champs dans la ou les secondes régions comprenant un compte d'utilisation actuel, un nombre maximal d'utilisations, et un état du cathéter d'imagerie intraluminal. Sont également divulgués des dispositifs, des systèmes et des procédés associés.
Patent EP-4031056-A2 (EP)
Title: Radiolucent surgical retractor
Inventor: SANDHAM NICK
IPC: A61B17/34
Filed: 2020-09-18
Abstract: A self-supporting surgical retractor is provided for retracting soft tissue and anatomy at a spinal surgical site. The retractor includes a tubular base defining an upper rim and a lower rim and a working channel there between the upper and lower rims, in which the base and lower rim are sized and configured to be seated on adjacent vertebral bodies spanning an intervertebral space. At least two elongated legs are provided, each projecting from the upper rim and each including a fixation feature at a free end thereof. Each of the legs has a length sufficient for the fixation feature to be outside the body of a patient when the lower rim is seated on adjacent vertebral bodies of the patient. The retractor is formed of a radio-transparent or radio-lucent material.
Patent EP-3986392-A2 (EP)
Title: Compounds for treatment of pd-l1 diseases
Inventor: MALATHONG VIENGKHAM
IPC: A61K31/137
Filed: 2020-06-19
Abstract: Compounds are provided that are useful as immunomodulators. The compounds have the Formula (I) including stereoisomers and pharmaceutically acceptable salts thereof, wherein R 1a , R 1b , R 1c , R 1d , R 2a , R 2b , R 3 , R 3a , R 4 , R 5 , R 6 , R 7 , R 8  and the subscript n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
Patent EP-4100519-A2 (EP)
Inventor: LIU DAVID R
IPC: C12N9/12
Filed: 2021-02-05
Abstract: The present disclosure provides adenine base editors (ABEs) that are variants of known adenine base editors. The adenosine deaminase domain of a known ABE was modified to produce adenosine deaminase variants. The deaminase variants provided herein have broader compatibility with diverse napDNAbp domains, such as Cas homologs, for base editing applications. The ABEs provided herein comprise a deaminase variant and a napDNAbp domain. The ABEs provided herein exhibit reduced off-target editing effects while retaining high on-target editing efficiencies. These ABEs exhibit reduced off-target DNA editing effects and reduced off-target editing effects in cellular mRNA. In addition, methods for targeted nucleic acid editing are provided. Further provided are pharmaceutical compositions comprising the ABEs. Also provided are vectors and kits useful for the generation and delivery of the ABEs, including vector systems for engineering the ABEs through directed evolution. Cells containing such vectors and ABEs are also provided. Further provided are methods of treatment comprising administering the ABEs.
Patent EP-4164876-A2 (EP)
Inventor: DRAGHETTI FIORENZO
IPC: B31F1/20
Filed: 2021-06-10
Abstract: Machine (10) to produce straws (11), preferably made of paper, comprising a feed unit (16) configured to feed a plurality of tubular elements, preferably made of paper, to different working units (17, 19, 20, 21) configured to automatically carry out different workings on the tubular elements (12), including at least one cut to make a pointed end (13), or an end cut obliquely, a deformation to make a bellows (14), a bend in correspondence with the bellows (14) and the packaging of each straw (11).
Patent EP-4235435-A2 (EP)
Title: Logging pages accessed from i/o devices
Inventor: MUKHERJEE SHRIJEET SUBHABRATA
IPC: G06F11/30
Filed: 2019-12-03
Abstract: Systems and methods of tracking page state changes are provided. An input/output is communicatively coupled to a host having a memory. The I/O device receives a command from the host to monitor page state changes in a region of the memory allocated to a process. The I/O device, bypassing a CPU of the host, modifies data stored in the region based on a request, for example, received from a client device via a computer network. The I/O device records the modification to a bitmap by setting a bit in the bitmap that corresponds to a location of the data in the memory. The I/O device transfers contents of the bitmap to the CPU, wherein the CPU completes the live migration by copying sections of the first region indicated by the bitmap to a second region of memory. In some implementations, the process can be a virtual machine, a user space application, or a container.
Patent EP-4234458-A2 (EP)
Title: System and method for conveying construction waste
Inventor: JOKILA JARI
IPC: B65G53/56
Filed: 2017-11-14
Abstract: System (1) for conveying construction waste, which system (1) comprises at least two containers (2, 3, 4), into which the construction waste is arranged to be conveyed from at least two different input locations (5, 6), a suction device (7), which is connectable into a flow connection with the selected containers (2, 3, 4) by means of a suction pipe (13). The system further comprises a pipe arrangement (8) connected to the containers (2, 3, 4) for forming a flow connection between the selected containers (2, 3, 4) and the input locations (5, 6), whereby the construction waste is arranged to be conveyed from the input locations (5, 6) into the selected containers (2, 3, 4) by means of the suction of the suction device (7).
Patent EP-4243322-A2 (EP)
Inventor: MORI MASAHITO
IPC: H04L5/00
Filed: 2015-07-31
Abstract: A first wireless communication device, comprising circuitry configured to wirelessly communicate with a second wireless communication device based on an Institute of Electrical and Electronics Engineers, IEEE, 802.11 standard; control schedule information to be included in a header portion of a physical layer protocol data unit, PPDU, defined in the IEEE 802.11 standard, wherein the schedule information is associated with orthogonal frequency-division multiple access, OFDMA; and control transmission of the PPDU to the second wireless communication device. The header portion comprises a first field, a second field, and a third field, the first field comprises flag information that identifies the second field and the third field, the second field comprises length information that indicates a length of the third field, the third field comprises a common field and a plurality of user specific fields, a combination of the common field and the plurality of user specific fields indicates resources to be used by each user, the common field comprises resource information related to a resource allocation for a data portion in frequency domain, the resource information being represented by first bits, a number of first number is set based on frequency bandwidth for transmission of the PPDU, the number of first bits is different between a first case in which the frequency bandwidth corresponds to 40 MHz, a second case in which the frequency bandwidth corresponds to 80 MHz, and a third case in which the frequency bandwidth corresponds to 80+80 MHz. Each user specific field of the plurality of user specific fields comprises a terminal identifier ID and Modulation and Coding Scheme MCS information, the terminal ID being represented by second bits, the MCS information being represented by a third bits, a number of second bits is larger than a number of third bits, and the number of third bits corresponds to 4.
Patent EP-4246965-A2 (EP)
Inventor: LIU HUI
IPC: H04N7/18
Filed: 2020-04-07
Abstract: The application discloses a data processing method and device, equipment, and a computer-readable storage medium, and relates to the field of data processing. The method includes allocating n low-level buffers and a temporary buffer for each of multiple videos, wherein n is an integer greater than or equal to 2; cyclically storing, when a respective video of the multiple videos is processed, respective frames in the respective video into respective ones of the low-level buffers corresponding to the respective video in sequence; and reading a frame to be processed from a corresponding one of the low-level buffers corresponding to the respective video to the temporary buffer corresponding to the respective video for processing. The solution can be applied to the field of artificial intelligence, especially to the field of autonomous driving (including autonomous parking).
Patent EP-4272715-A2 (EP)
Inventor: BAHMANI HAMED
IPC: A61F9/00
Filed: 2018-06-08
Abstract: A method for application of light to one or more eyes (300) of a user is disclosed. The method comprises identification (110) of location of an optic disk (330) on a retina (320) in the one or more eyes (300) and selectively applying (115) the light onto the optic disc (330) to stimulate the optic disk (330).
Patent EP-4303541-A2 (EP)
Inventor: KAEHLER ADRIAN
IPC: G01D5/26
Filed: 2016-05-19
Abstract: An apparatus comprising a processor (714); a wearable head device including a transmissive display (700) comprising a waveguide (702) with an input face and an output face having an exit location (710); and a diffractive optical element (704), DOE, formed across the waveguide (701) and configured to couple input light into the waveguide and direct the input light via total internal reflection to the exit location; and a light sensor (712) configured to receive the input light via the waveguide (702) and generate a sensor output signal corresponding to the received input light, wherein the processor (714) is configured to generate an output based on the sensor output signal, the output comprising a rectilinear array of pixel values, the sensor output signal comprises one or more incoming pixel values, and generating the output comprises determining, for a first pixel value of the rectilinear array of pixel values, a corresponding incoming pixel value.
Patent EP-0026466-A2 (EP)
Inventor: KUHNER ERNST EWALD
IPC: E02F3/54
Filed: 1980-09-25
Abstract: 1. A scraper apparatus with a jib (9) stretching out over an aggregate store and able to be turned thereover and which at its central end is turnable joined to a base (4), with a winch (8) next to the base, and a scraper bucket (12) moved by the winch by way of a rope, the rope consisting of a pulling rope (13) directly fixed to the scraper bucket and a return rope (14, 16) running from the winch along the jib round at least one deflection pulley (15) at the free end of the jib to the scraper bucket, characterized in that the jib (9) is turnable joined at the front side of the base (6) of a driver's cabin (5), that the winch (8) is placed on the rear side opposite to the jib, that a lever (19) is turnable joined to the cabin of the apparatus and that in the path of the return rope (14, 16) and on the free end of the lever (19) a rope pulley (18) is turnable mounted, which is movable from an operation position into a position for shortening the return rope (16) and has in every position a sufficient distance to the drum (8) of the winch so that the fleat angle between the winch and the rope pulley (18) rests in harmless limits.
Patent EP-0022431-A2 (EP)
Inventor: ANNERFALK KARL-ERIK
IPC: F41C23/00
Filed: 1980-06-10
Abstract: A combined shoulder support-cheek support for fire arms of the type, comprising a barrel (3-5) on which the shoulder support-cheek support (6) is mounted. The shoulder support is formed so that it can be optionally adapted to right handed marksmen or left handed marksmen and it comprises a box (13) which is mounted directly on the barrel (3) and which at the upper side and lower side respectively carries a support bar (20, 21). The support bars (20, 21) are interconnected at their rear ends by means of a hinge ribbon (19) which extends through the box, and at the support bar ends which can be fold out the support bars (20, 21 ) are interconnected by means of a shoulder support ribbon (18) which extends freely through the said box and which is of such length that either of the support bars (20, 21) can be fold out to a position substantially at right angle to the box (13) whereas the opposite support bar provides a stop for such folding out
Patent EP-0036847-A2 (EP)
Inventor: WIREDAL HARRY ARTUR INGVAR
IPC: E21B10/40
Filed: 1981-02-06
Abstract: A drill tool for rotary and/or percussion drilling with drill rod means (14) within casing tube means (15) comprises a centric cutting bit (11) and an eccentric reamer cutter (12), both provided with hard metal inserts. For purposes of obtaining a life of the drill tool as long as possible the first frontal insert (23) on the reamer cutter (12) is positioned in front of the first peripheral insert (18) when seen in the rotational direction (D) during drilling, and the centric cutting bit (11) provided with more inserts on the half (38) of its front surface opposed to the reamer cutter (12) during drilling than on the other half (39).
Patent EP-0057912-A2 (EP)
Inventor: CORRIGAN FRANCIS RAYMOND
IPC: C09K3/14
Filed: 1982-02-09
Abstract: Boron rich cubic boron nitride suitable for use in electroplating processes (e.g. nickel plating) has been made by an acid leaching process. Boron rich aggregated cubic boron nitride grinding grits are leached in a mixture of nitric and sulfuric acids, the following conditions being typical; (a) volume ratio of 67% nitric acid to 98% sulfuric acid of 10:20; (b) temperature of 250 DEG  C; and (c) for a time of 1 hour. The process removes sufficient free surface boron to reduce the conductivity at the surface, resulting in an abrasive which does not overplate. FIG. 1 is a photomicrograph of a typical plated surface containing the improved CBN grinding grit of this invention, and FIG. 3 is an X-ray diffraction pattern characteristic of this new product.