Patent GB-918456-A (GB)
Title: Preparations containing silicones
Filed: 1961-06-16
Abstract: A free-flowing pulverulent solid, useful as an antifoaming agent, consists essentially of (1) 5 to 100 parts (by wt.) of a silicone antifoam agent dispersed on (2) 100 parts of a pulverulent solid selected from lactose, sodium bicarbonate, magnesium oxide, hydroxide and stearate, and solid carboxyvinyl resin copolymers.  The dispersion is effected merely by mixing together the desired ingredients.  The silicone antifoam agent used is preferably a liquid siloxane containing silicon-bonded methyl, ethyl or 3,3,3-trifluoropropyl radicals, and may contain a silica or other inert, water-insoluble, inorganic filler, as described in Specifications 639,673, 689,306 and 859,329.  Other optional additives are flavourings, colouring agents, bacteria inhibitors, surfactants, binding agents to obtain suitable tablets and medicaments.  Examples are given.  U.S.A. Specification 2,934,472 also is referred to.ALSO:A free-flowing pulverulent solid consists essentially of (1) 5 to 100 parts (by wt.) of a silicone antifoam agent dispersed on (2) 100 parts of a pulverulent solid selected from lactose, sodium bicarbonate, magnesium oxide, hydroxide and stearate, and solid carboxy vinyl resin copolymers.  The dispersion is effected merely by mixing the desired ingredients together.  The silicone antifoam agent used is a liquid siloxane containing Si-bonded hydrocarbon (saturated or unsaturated) or halohydrocarbon radicals, preferably methyl, ethyl or 3,3,3-trifluoropropyl radicals, and may contain a silica or other inert, water-insoluble, inorganic filler, as described in Specifications 639,673, 689,306 and 859,329.  Other optional additives are flavourings, e.g. citric acid and oil of peppermint, colouring agents, bacteria inhibitors, e.g. sorbic acid, surfactants, binding agents to obtain suitable tablets, and medicaments.  In a typical example (1) gum acacia, starch, dimethylpolysiloxane (a mixture of liquid and gum), silica, sodium bicarbonate and lactose, were mixed together to give a dry, flowable powder, which was subsequently tabletted.  Uses: As an antifoaming agent; for relieving gas pains and neutralizing hyperacidity in humans.  U.S.A. Specification 2,934,472 also is referred to.ALSO:A free-flowing pulverulent solid, for relieving gas pains and neutralizing hyperacidity in humans, consists essentially of (1) 5 to 100 parts (by wt.) of a silicone antifoam agent dispersed on (2) 100 parts of a pulverulent solid selected from lactose, sodium bicarbonate, magnesium oxide, hydroxide and stearate, and a solid carboxyvinyl resin copolymer.  The disperson is effected merely by mixing together the desired ingredients.  The silicone antifoam agent used is preferably a liquid siloxane containing silicon-bonded methyl, ethyl or 3.3.3-trifluoropropyl radicals, and may contain a silica or other inert, water-insoluble, inorganic filler, as described in Specifications 639,673, 689,306 and 859,329.  Other optional additives are flavourings, colouring agents, bacteria inhibitors, surfactants, binding agents to obtain suitable tablets, and medicaments.  Examples are given.  U.S.A. Specification 2,934,472 also is referred to.