baber/WOPTO huggingface dataset:
Patent CA-2241244-C (CA)
Title: Use of inhibitors of the activity of retinoic acid for treating sensitive skin and/or acute damage induced by uv radiation
Inventor: DEMARCHEZ MICHEL
IPC: A61K8/00
Filed: 1997-10-20
Granted: 2005-01-11
Abstract: The invention concerns the use of at least one inhibitor of the activity of retinoic acid in a cosmetic composition or for making a pharmaceutical composition, the inhibitor of the activity of retinoic acid or the pharmaceutical composition being designed for treating sensitive skin and/or skin damage induced by UV radiation.
Patent CA-2241291-C (CA)
Inventor: NARAYAN THIRUMURTI
IPC: C08G18/30
Filed: 1998-07-22
Granted: 2009-09-22
Abstract: The present invention relates generally to polyisocyanate compositions for use in polyurethane thermoformable foams. The polyisocyanate compositions of the present invention which are also useful as binder/hardeners for prefoamed products offer improved stability at relatively low temperatures over other known polymeric diphenylmethane diisocyanate compositions.
Patent CA-2241843-C (CA)
Title: Plate-type crossflow air-to-air heat exchanger having dual pass cooling
Inventor: STARK WALTER
IPC: F24F3/153
Filed: 1996-09-12
Granted: 2008-12-02
Abstract: A heat exchanger (40) for dehumidifying a stream of air including heat conducting channel walls (42) which serve as the heat exchange surface for precooling and reheating air during the dehumidification process. Cooling conduits (48) are positioned in a plane parallel to a plane defined by the heat conducting walls (42), such that cooling occurs both in the intake and exhaust airstreams, and the airflow is redirected in a small plenum chamber (44) located at an end of the channels adjacent the cooling conduits (48). A  system is also provided which includes a plurality of heat exchangers in series sharing a common cooling coil and a common plenum chamber.
Patent CA-2244341-C (CA)
Inventor: LEEVER DAVID L
IPC: A61C11/00
Filed: 1997-01-28
Granted: 2005-08-02
Abstract: La présente invention se rapporte de manière générale à un appareil et un procédé destinés à positionner un modèle d'arcade dentaire maxillaire (13) dans un articulateur dentaire dans le but de simuler le positionnement d'une arcade dentaire maxillaire représentée par le modèle d'arcade. On peut positionner ledit modèle d'arcade sur une plaque (14) ayant une surface sensiblement plane dotée d'un point d'articulation (20) à travers lequel sont alignés trois axes, généralement perpendiculaires les uns par rapport aux autres. Il est en outre possible de fixer la plaque, de manière détachable, à un articulateur et de l'ajuster par rapport auxdits axes en fonction de trois mesures linéaires et de trois mesures angulaires associées au positionnement de l'arcade dentaire maxillaire d'un patient au sein du crâne dudit patient.
Patent CA-2245647-C (CA)
Title: Nouveaux aminoacides cycliques pontes utilises comme agents pharmaceutiques
Inventor: HORWELL DAVID CHRISTOPHER
IPC: A61K31/195
Filed: 1997-02-18
Granted: 2006-03-21
Abstract: L'invention concerne de nouveaux aminoacides cycliques pontés de la formule (I) utiles comme agents de traitement de l'épilepsie, d'évanouissements, d'hypocinésie, de maux de tête, de maladies neurodégénératives, de la dépression, de l'anxiété, de peurs paniques, de douleurs et de troubles neuropathologiques. L'invention concerne également des procédés de préparation de ces composés et des intermédiaires de cette préparation.
Patent CA-2247188-C (CA)
Inventor: ZEIKUS JOSEPH G
IPC: C12R1/01
Filed: 1997-02-25
Granted: 2002-08-06
Abstract: La présente invention concerne en général les phosphatases alcalines et en particulier les phosphatases alcalines issues de micro-organismes hyperthermophiles. L'invention concerne également un procédé de purification d'une phosphatase alcaline hyperthermophile.
Patent CA-2251991-C (CA)
Inventor: VAAL MARK J
IPC: C07F7/08
Filed: 1997-03-03
Granted: 2002-05-14
Abstract: This invention relates to compounds of formula (1), wherein R1 and R6 are each independently C1-C6 alkyl; R2, R3 and R4 are each independently hydrogen or C1-C6 alkyl; R is hydrogen or -C(O)-(CH2)m-Q wherein Q is hydrogen or -COOH and m is an integer 1, 2, 3 or 4; Z is a thio, oxy or methylene group; A is a C1-C4 alkylene group; R5 and R7 are each independently a C1-C6 alkyl or -(CH2)n-(Ar) wherein n is an integer 0, 1, 2 or 3; and Ar is phenyl or naphthyl unsubstituted or substituted with one to three substituents selected from the group consisting of hydroxy, methoxy, ethoxy, halogen, trifluoromethyl, C1-C6 alkyl, or -NR8R9, wherein R8 and R9 are each independently hydrogen or C1-C6 alkyl; with the proviso that when R2 and at least one of R5 or R7 is C1-C6 alkyl, and Ar is not substituted with trifluoromethyl or -NR8R9, then R is -C(O)-(CH2)m-Q; or a pharmaceutically acceptable salt thereof; useful for the treatment of atherosclerosis and chronic inflammatory disorders; for inhibiting cytokine-induced expression of VCAM-1 and/or ICAM-1; for inhibiting the peroxidation of LDL lipid; for lowering plasma cholesterol; and as antioxidant chemical additives useful for preventing oxidative deterioration in organic materials.
Patent CA-2258843-C (CA)
Title: Biodegradable polymeric mixtures based on thermoplastic starch
Inventor: SCHMIDT HARALD
IPC: C08L3/00
Filed: 1997-06-20
Granted: 2005-04-19
Abstract: For converting native starch or starch derivatives into thermoplastic starch, it is proposed that the starch, which is principally responsible for the conversion, be mixed with at least one hydrophobic, biodegradable polymer. This hydrophobic, biodegradable polymer which serves as a plasticising or swelling agent, can be a polymer from the following list: an aliphatic polyester, a copolyester with aliphatic and aromatic blocks, a polyester amide, a polyester urethane, a polyethylene oxide-polymer or a polyglycol and/or mixtures thereof. During the melting process, when mixing the starch, such as native starch in particular or derivatives thereof, with the hydrophobic, biodegradable polymer as a plasticising or swelling agent, to homogenise the mixture, the water content is to be reduced to < 1 wt. % in relation to the weight of the mixture.
Patent CA-2261578-C (CA)
Title: Adn regulateur de l'expression genique, cassette d'expression, vecteur d'expression et plante transgenique
Inventor: KIHARA MAKOTO
IPC: A01H5/00
Filed: 1997-07-22
Granted: 2005-09-20
Abstract: La présente invention concerne un ADN régulateur de l'expression génique. Cet ADN régulateur de l'expression génique comporte un site promoteur, issu du gène D-hordéine de l'orge, et permettant l'expression du gène désiré, et un site régulateur permettant de réguler l'expression du gène considéré en fonction du site promoteur considéré. Ce site régulateur est constitué au moins d'un site activateur permettant d'activer l'expression du gène considéré et d'un site suppresseur permettant de supprimer l'expression du gène considéré. L'utilisation de cet ADN régulateur de l'expression génique permet de réguler comme on le souhaite l'expression du gène à l'intérieur d'une cellule de végétal tel que l'orge.
Patent CA-2269125-C (CA)
Title: Films s'utilisant dans le conditionnement sous atmosphere modifiee de denrees perissables
Inventor: YOUNG GINA L
IPC: C08J5/18
Filed: 1997-11-03
Granted: 2007-01-09
Abstract: L'invention concerne une structure de film appropriée pour le conditionnement de denrées périssables, comprenant au moins une couche de film, comprenant à son tour un mélange d'au moins un polymère d'éthylène homogène linéaire ou sensiblement linéaire et au moins un polymère de polypropylène. La structure de film est caractérisée par le fait qu'elle contient un module sécant de 2 %, au moins supérieur de 8 % à celui d'une structure de film comparable préparée sans le polymère de propylène, et un taux de transmission de l'oxygène d'au moins 700cc(à STP)-mil/100 in.<2>-jour-atm (0,027cc-(à STP)-cm/cm<2>-jour-MPa) à 25  DEG C. Les structures de film selon l'invention possèdent un équilibre de propriétés optimisé, ce qui les rend particulièrement utiles pour le conditionnement sous atmosphère modifiée de denrées périssables. Les films selon l'invention sont particulièrement indiqués pour le conditionnement de fruits et légumes frais ainsi que d'autres articles périssables pour lesquels un accès régulé à l'oxygène ambiant pourrait s'avérer profitable.
Patent CA-2269393-C (CA)
Inventor: FEIGEL KURT R JR
IPC: E21B19/00
Filed: 1999-04-21
Granted: 2008-02-12
Abstract: A power tong system, comprising a frame having a rear support and a front support, the front support comprising a first front leg and a second front leg; and a power tong mounted in the frame with the power tong extending transversely between the first front leg and the second front leg, the first front leg and the second front leg forming a guide preventing transverse motion of the power tong while allowing vertical movement of the power tong. The system is also preferably provided with a backup tong. The sides of the power tong are preferably provided with rollers to prevent friction between the power tong and the guide. In a second power tong system, a load cell assembly is provided in which a load cell is linked by a series of links to the power tong such that movement by the power tong in either of two transverse directions loads the load cell. In a third power tong system, an improved backup tong is provided in which jaws, preferably symmetrically disposed on the backup tong and each carrying dies, are moved about pivots by a rigid link between the jaws and a linear actuator. The dies are preferably provided with more than one die seat for locating the dies at different positions on the jaws. A third die may be provided, preferably symmetrically arranged with the dies on the jaws. The third die may be located on the linear actuator.
Patent CA-2269439-C (CA)
Inventor: SHAPIRO JACK M
IPC: B60R19/42
Filed: 1999-04-20
Granted: 2007-04-03
Abstract: An improved strengthening or reinforcing member, and in particular an automotive vehicle door reinforcing beam, constructed from ultra high strength steel is disclosed. The door reinforcing beam has a substantially trapezoidal shaped cross-sectional geometry and optionally can include an additional reinforcement extending over a central portion of the beam. In an alternative embodiment, a rounded outboard flange portion can be substituted for a generally flat outboard flange portion. The door reinforcing beam exhibits a substantial improvement in load carrying capability for a given mass, as compared to door reinforcing beams having other cross-sectional geometries, such as hat-shaped cross-sectional geometries.
Patent CA-2271136-C (CA)
Title: Novel pyridonecarboxylic acid derivatives or salts thereof and drugs containing the same as the active ingredient
Inventor: HIRAO YUZO
IPC: C07D471/04
Filed: 1997-11-27
Granted: 2008-11-25
Abstract: The invention relates to pyridonecarboxylic acid derivatives represented by the general formula (1):      wherein R1 is -OH, a carboxy-protecting group or (alkyl)-amino group, R2 is H, or -NO2, (protected) amino, (protected) hydroxyl, lower alkyl or lower alkoxyl group, R3 is a halogen atom, H, or -NO2, lower alkyl, lower alkoxyl or amino group, R4 is an azido, (substituted) hydrazino, (substituted) amino, lower alkoxyl or hydroxyl group, R5, R6 and R7 are independently H, -NO2, halogen atom or lower alkyl group, R8 is a-NO2, (substituted) amino, -OH or lower alkoxyl group, A is N or C-R12, in which R12 is H, halogen atom, or (substituted) lower alkyl, lower alkenyl, lower alkynyl, lower alkoxyl, lower alkylthio or nitro group, and B is N or C-R13, in which R13 is H or halogen atom, or salts thereof, and medicine comprising such a compound as an active ingredient. The derivatives or the salts thereof exhibit excellent antibacterial action and peroral absorbability, scarcely cause side effects, and are easy of synthesis.
Patent CA-2275592-C (CA)
Title: Method for preparing a tetrahydropyridin derivative
Inventor: BUJ MICHEL
IPC: C07C29/147
Filed: 1997-12-23
Granted: 2005-09-06
Abstract: The invention relates to a method for the preparation of 1-[2-(2- naphthyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine and i ts pharmaceutically acceptable salts by reacting 2-(2-bromoethyl)naphthalene wi th 4- (3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine or one of its salts, an d to a universal method for the preparation of the same product and its salts by th e reduction of naphthylacetic acid, treatment of the resulting 2-naphthylethan ol with hydrobromic acid and treatment of the 2-(2-bromoethyl)naphthalene with 4-(3- trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine or one of its salts.</SDOA B>
Patent CA-2275661-C (CA)
Inventor: KOOCHIN CAREY
IPC: F16D65/00
Filed: 1999-06-16
Granted: 2007-11-20
Abstract: A tool is described for adjusting a slack adjuster. A slack adjuster includes an adjustment bolt and a sealing plate disposed about the adjustment bolt. The tool includes an end including a hex-shaped aperture for engaging the hex-shaped head of the adjustment bolt. The tool also includes an annular face including a pair of spaced apart pins for engaging the sealing plate. A hex is formed on the outer surface of the tool for engagement by a wrench.
Patent CA-2276114-C (CA)
Inventor: IZUMI JUN
IPC: C02F1/78
Filed: 1999-06-21
Granted: 2004-08-31
Abstract: A polluted fluid containing at least one pollutant is processed by passing the polluted fluid through an adsorbing layer containing a high-silica adsorbent capable of adsorbing both ozone and at least one pollutant to adsorb at least one pollutant on the adsorbent. Then, ozone is brought into contact with the adsorbing layer to oxidize and decompose the pollutant adsorbed on the adsorbent, while stopping the flow of the polluted fluid.
Patent CA-2280710-C (CA)
Inventor: BERBEN PIETER HILDEGARDUS
IPC: B01J23/44
Filed: 1998-02-12
Granted: 2007-08-21
Abstract: The invention concerns a process for hydrogenation, hydroisomerization and/or hydrodesulfurization of a sulfur contaminant containing hydrocarbon feedstock, wherein the feedstock is contacted in the presence of hydrogen gas with a catalyst, which catalyst comprises platinum, palladium or a combination thereof on a non-crystalline, acidic silica-alumina support, which support is obtained by sol-gel techniques and wherein the ratio of Si to Al is from 1:10 to 200:1.
Patent CA-2281751-C (CA)
Inventor: SATO TAICHI
IPC: F16L21/08
Filed: 1999-09-09
Granted: 2008-11-04
Abstract: A tube joint comprises: a pushing ring provided at its outer periphery with a projection and fitted to an outer periphery of one end of a joint tube; a tube or a joint body provided at is side opposed to the pushing ring with a projection opposed to the projection of the pushing ring, the tube or the joint body having a receiving portion which is widened toward the pushing ring and the tube or the joint body being fitted to an outer periphery of the joint tube with a peripheral gap left therebetween; a fastening tool capable of moving the pushing ring in a direction of the tube or the joint body; a packing provided between inner and outer side of the tube or the joint body and the joint tube, and fitted through the receiving portion by its own resilient deformation by operation of the fastening tool; and a spacer inserted between the pushing ring and the tube or the joint body to limit a distance between the pushing ring and the tube or the joint body to a constant value
Patent CA-2282130-C (CA)
Inventor: PFEIFFER DOHN WILLIAM
IPC: A01F7/06
Filed: 1999-09-14
Granted: 2002-11-26
Abstract: A variable sweep infeed element for a rotary combine is bolted to the infeed section of the rotor drum and extends radially outward therefrom. The element is provided with a forward portion and a rearward portion. The forward portion is the location where the infeed element first contacts the crop mat. The forward portion has a radial section that extending radially outward from the rotor drum and an outermost section is forward swept in the direction of rotor rotation. This forward sweep is most aggressive at the initial feeding point and becomes less aggressive as the forward portion extends longitudinally downstream towards the transition point between the forward portion and the rearward portion. The rearward portion is provided with a radial section extending radially outward from the rotor drum and an outermost
Patent CA-2284077-C (CA)
Title: Variants of ciliary neurotrophic factor with enhanced receptor selectivity and method for their selection
Inventor: LAUFER RALPH
IPC: A61K38/00
Filed: 1998-03-20
Granted: 2002-12-03
Abstract: The subject of the present invention are variants of ciliary neurotrophic factor with enhanced receptor selectivity (CNTFR), useful for the treatment of diseases and disorders including motor neuron diseases and muscle degenerative diseases. Another subject of the invention is to provide a method for identifying the above mentioned CNTF variants. The hCNTF variants with the amino acid substitutions in accordance with the present invention, have a reduced ability, as compared to the human CNTF, to elicit biological effects through soluble CNTFR, without affecting its ability to activate membrane-bound neuronal CNTF receptors, thereby improving its therapeutic properties.  Fig. 1 shows the reduced CNTFR binding affinity of a CNTF variant according to the invention (IA-CNTF; SEQ ID NO:2). It is evident that the binding affinity of this variant to the CNTFR is reduced as compared to the wild-type human CNTF molecule.
Patent CA-2285282-C (CA)
Title: Detection of low level hydrophobic analytes in environmental samples
Inventor: ROSEN STEVEN M
IPC: G01N31/20
Filed: 1998-04-02
Granted: 2005-02-22
Abstract: Apparatus and method for detection of low levels of about 1 ppb of hydrophobic analyte in environmental samples using an enclosed permeable membrane enrichment device and agglutination reaction slide test apparatus, said permeable membrane comprising silica particles having been coated with an aliphatic hydrophobic phase.
Patent CA-2288951-C (CA)
Inventor: NEUFELD GEORGE
IPC: A01C7/00
Filed: 1999-11-04
Granted: 2008-06-17
Abstract: A nurse inductor mechanism for an agricultural seeding implement converts an air seeder meter box into a nurse inductor box to convey seed particles to the singulator of a planting mechanism. The nurse inductor mechanism is detachably mounted on the meter box of the air seeder to receive a supply of seed particles therefrom. The nurse induction mechanism intercepts the normal air flow for the metering mechanism to divert the stream of air into engagement with a pile of seed particles and induce the entrainment of the seed particles for conveyance thereof to the remote planting mechanism. A partition wall divides the nurse induction mechanism into a seed side and an air side. The seed side receives the supply of seed particles from the hopper and allows the seed to pass through a passageway into the air side for engagement by the stream of air. Divider walls are provided to isolate each discharge tube from the other discharges tube so that the planter mechanisms can provide a continuous supply of seed particles. The discharge tubes pass through the nurse induction mechanism in a stacked pair, modular configuration with the respective discharge tubes being adequately separated with respect to the seed side to permit the passage of seed particles therebetween.
Patent CA-2290264-C (CA)
Inventor: VAUGHN ROGER
IPC: G02B6/44
Filed: 1999-11-23
Granted: 2008-02-05
Abstract: An optical fiber cable core includes a buffer tube containing at least one optical fiber and reinforced by at least two substantially radially incompressible longitudinal strength members, each strength member having surface portions radially outermost with respect to the tube axis which are at or protrude from the exterior surface of the buffer tube. If the strength members protrude from the exterior surface of the buffer tube, less than 50%, and preferably less than 20%, of the outer surface of the strength members protrudes from the exterior surface of the buffer tube. The positions of the strength members can be readily determined, can be visible and can be easily removed from the buffer tube prior to slitting the buffer tube to achieve midspan access. The core can include a buffer tube having an inner tubular portion, an outer tubular portion including the strength members, and a release agent between the tubular portions to enable easy separation of the tubular portions so that conventional slitting tools can be used to gain midspan access. Also, an optical fiber cable including the core and methods of manufacturing a reinforced buffer tube are disclosed.
Patent CA-2290671-C (CA)
Title: Method of coating a metallic substrate with thermoplastic coating material
Inventor: BEENTJES PETRUS CORNELIS JOZEF
IPC: B32B27/32
Filed: 1998-05-14
Granted: 2004-09-14
Abstract: Method of coating a metallic substrate (1) with thermoplastic coating material, comprising a preheating the substrate in such as way that, just prior to coating, it is at a temperature between 70 °C and 150 °C, preferably between 100 °C and 130 °C in the case of a coating containing polypropene and between 80 and 110 °C in the case of a coating containing polyethene;  coextrusion, in the first coating station of a sheet (6) comprising a polyolefin covering layer and a modified polyolefin adhesion layer;  coating of the substrate (1) with a molten sheet in the presence of ozone by pressing it with the adhesion layer against the surface of the substrate; transportation of the strip (9) coated on one side to a second coating station and heating the strip so that, just before coating, the strip is at a temperature between 70 °C and 130 °C, preferably between 80 °C and 120 °C, if the coating layer applied in the first coating station is polypropene and between 80 and 110 °C if the coating layer applied at that point is polyethene; coating of the substrate with a molten sheet extruded in the second coating station by pressing it against the uncoated surface of the substrate, use being made of the presence of ozone; heating of the coated substrate so that it assumes a temperature which is above the melting point of the polyolefins applied; cooling of the coated substrate.
Patent CA-2294077-C (CA)
Title: Two-tier can package having divider panel and method of forming the same
Inventor: STOUT JAMES T
IPC: B65D71/00
Filed: 1998-06-08
Granted: 2004-04-06
Abstract: A collapsed carton for subsequent setup to receive articles includes top and bottom panels and a pair of side panels. End closure flaps extend from opposite side edges of each of the side panels to close th e tubular carton when set up. A divider panel is disposed within the tubular structure between the top and bottom panels. A pair of glue flap s are foldably connected to the divider panel side edges, each of the glue flaps being secured to an inner surface of one of the side panel s to retain the divider panel within the tubular structure. At least one divider end flap is foldably connected to one of the divider panel end edges. A first aperture is defined through one divider end flap. A second aperture is defined through one of the end closure flaps at one of the tubular ends of the carton to coincide with the first aperture when the carton is collapsed.
Patent CA-2295395-C (CA)
Inventor: HIROSE KEIJI
IPC: C08L23/16
Filed: 1994-01-11
Granted: 2003-09-16
Abstract: Disclosed is a propylene polymer composition comprising (A5) 5-95 wt. % of propylene homopolymer obtained by polymerizing propylene in the presence of a catalyst comprising (i) a transition metal compound of the formula:   (see formula I) (wherein M is a transition metal, R1 is hydrocarbon, R2 is aryl, X1 and X2 are hydrogen, halogen, hydrocarbon or the like and Y is a divalent group such as hydrocarbon) and (ii) an organoaluminium oxy-compound or the like and 95-5 wt. % of at least one other ingredient selected from another propylene polymer, an olefin elastomer and another olefin polymer. The composition may be used for molding articles.