baber/WOPTO huggingface dataset:
Patent PT-1250327-E (PT)
Title: Process for producing n-halogenated organic compounds
Inventor: ELNAGAR HASSAN Y
IPC: C07D251/36
Filed: 2001-01-17
Abstract: The process enables highly effective N-halogenation of a compound having one or more halogenatable amido or imido functional groups in the molecule. The process involves, for example, concurrently feeding into a reactor (i) water, inorganic base, and the compound to be N-halogenated, e.g., a hydantoin, and a feed of (ii) a brominating agent and/or a chlorinating agent. The proportions of these feeds are such that the pH is kept within the range of ca. 5.5-8.5 (preferably 6.5-8.5, and most preferably 6.8-7.2) and one or more of the amido or imido nitrogen atoms is substituted by a bromine or chlorine atom. A feature of the process is that it can be conducted at elevated temperatures as high as about 90° C. without appreciable thermal decomposition of reactants or product. The resultant product continuously precipitates in high yield and purity. Moreover, products can be produced that are very pale yellow to almost pure white in appearance. Further, the process has been found capable of producing 1,3-dibromo-5,5-dimethylhydantoin with far larger particle sizes than previously produced on a commercial basis.
Patent PT-1315715-E (PT)
Title: Quinazoline derivatives as kinase inhibitors
Inventor: PANDEY ANJALI
IPC: C07D403/12
Filed: 2001-08-17
Abstract: The present invention relates to nitrogen-containing heterocyclic compounds and pharmaceutically acceptable salts thereof which have inhibitory activity on the phosphorylation of kinases, which inhibits the activity of such kinases. The invention is also related to a method of inhibiting kinase and treating disese states in a mammal by inhibiting the phosphorylation of kinases. In a particular aspect the present invention provides nitrogen-containing heterocyclic compounds and pharmaceutically acceptable salts thereof which inhibit phosphorylation of a PDGF receptor to hinder abnormal cell growth and cell wandering, and a method for preventing or treating cell-proliferative diseases such as arteriosclerosis, vascular reobstruction, cancer and glomerulosclerosis.
Patent PT-1343708-E (PT)
Inventor: JUHA LUMPPIO
IPC: B22D30/00
Filed: 2001-12-11
Abstract: An arrangement for conveying an anode plate from one location to another, whereby said arrangement comprises gripping elements attached to a conveyor for gripping a plate-like piece. Elements are attached to the gripping element connection for the correction, at least partial, of any possible positional error of the anode to be transferred.
Patent PT-1448356-E (PT)
Inventor: ALAIN LEVEQUE
IPC: B29C48/67
Filed: 2002-11-20
Abstract: An apparatus for mixing thermoplastic materials is provided. The apparatus includes a barrel and a screw rotatably mounted in the barrel. The screw has a screw shaft with a thread spirally extending around the screw shaft so as to form a plurality of flights, and the screw has a zone through which melted polymer conveyed. The screw has a portion that is without a screw thread where the screw shaft forms a mixing element with a drum-shaped surface extending above the screw shaft that is coaxial with the screw shaft. This drum-shaped surface has a plurality of alternating input grooves output grooves extending in a generally axial direction. Lands extend between the input grooves and output grooves so as to separate the input grooves from the output grooves, with the length of each land being substantially equal to the length of the contiguous portion of the adjacent input and output grooves. There is a land cross-sectional shear area corresponding to each land that is equal to the length of the land multiplied by the clearance between the land and the inside surface of the barrel hollow space, and the summation of the land cross-sectional shear areas for all of the lands of the mixing element is greater than or equal to 95% of the flow cross-sectional area between the adjacent flights of the screw through which polymer passes immediately prior to entering the mixing element.
Patent PT-1525177-E (PT)
Title: Substituted 1,3-diphenylprop-2-en-1-one derivatives, preparation and uses thereof
Inventor: NAJIB JAMILA
IPC: C07C281/00
Filed: 2003-07-08
Abstract: The invention concerns novel substituted 1,3-diphenylprop-2-en-1-one derivatives, pharmaceutical compositions comprising same, their therapeutic uses, in particular for treating cerebral ischemia. The invention also concerns a method for preparing said derivatives.
Patent PT-1601863-E (PT)
Title: Exhaust system
Inventor: FLETCHER TREVOR LEE
IPC: F01N3/28
Filed: 2004-03-01
Abstract: An exhaust system (10) for an engine system, the exhaust system (10) comprising a pipe system (12) having at least one input port (15, 16) for receiving exhaust gases from the engine (14) system and at least one output port (18) for venting exhaust gases from the exhaust system (10) wherein the pipe system (12) includes at least two exhaust routes for flow of gases from the one or more input ports (15, 16) to the one or more output ports (18), and further includes a diverter valve (28) operable in response to a control input to control the flow of exhaust gases through the pipe system (12) through one or more of the exhaust routes, the diverter valve (28) comprising at least two butterfly valve members (36), each butterfly valve member (36) controlling the flow of exhaust gases via one of said exhaust routes, each member having an input face (21) and an output face (23), at least one input face (21) comprising input disrupting means (50) for disrupting the flow of exhaust gases emitted from the engine (14) system.
Patent PT-1649886-E (PT)
Title: Unit dose capsules for a dry powder inhaler
Inventor: STEINER SOLOMON S
IPC: A61J3/07
Filed: 2000-07-21
Abstract: The dry powder inhaler (10) comprises an intake section (20); a mixing section (30), and a mouthpiece (40). The mouthpiece is connected by a swivel joint to the mixing section, and may swivel back into the intake section and be enclosed by a cover (290). The intake chamber comprises a piston with a tapered piston rod and spring, and one or more bleed-through orifices to modulate the flow of air through the device. It optionally comprises a feedback module to generate a tone indicating when the proper rate of airflow has been achieved. The mixing section holds a capsule (300) with holes containing a dry powder medicament, and further opens and closes the capsule when the intake section is at a certain angle to the mouthpiece. The mixing section is a Venturi chamber to impart a cyclonic flow to air passing through the mixing chamber.
Patent PT-1711518-E (PT)
Title: Chimpanzee adenovirus vaccine carriers
Inventor: CIRILLO AGOSTINO
IPC: C07K14/075
Filed: 2005-01-18
Abstract: The present invention provides recombinant replication-defective adenoviral vectors derived from chimpanzee adenoviruses and methods for generating recombinant adenoviruses in human E1-expressing cell lines. The invention also provides compositions and methods suitable for use for the delivery and expression of transgenes encoding immunogens against which a boosted immune response is desired. The invention further provides methods of generating clinical grade vector stocks suitable for use in humans. In a particular embodiment the invention contemplates the use of vectors comprising transgenes which encode tumor associated antigens in vaccines and pharmaceutical compositions for the prevention and treatment of cancer.
Patent PT-1763546-E (PT)
Title: Water-soluble copolymers containing sulfo groups, method for the production and use thereof
Inventor: PFEUFFER THOMAS
IPC: C08F220/58
Filed: 2005-06-30
Abstract: The invention relates to water-soluble copolymers used as water retention agents, stabilizers and rheology modifiers in aqueous building material systems based on hydraulic binders such as cement, lime, plaster, anhydrite etc. and in water-based paint and coating systems. The inventive copolymers are highly effective water retention agents even when used in relatively small amounts. They also exhibit excellent air pore stability and adhesiveness. They can also be used as stabilizers in building material and paint systems.
Patent PT-1768923-E (PT)
Title: Lift and pulley assembly for use in a lift
Inventor: FISCHER DANIEL
IPC: B66B11/08
Filed: 2005-07-12
Abstract: An elevator comprises an elevator car and support belts that form a 4:1 suspension for the elevator cabin and that are looped several times beneath the elevator car. Several parallel, flat belts are used and the rollers of at least one fixed roller group that diverts the belts are positioned in such a way that the belt sections of the parallel belts lie vertically above one another in the vicinity of the belt diversion.
Patent PT-1809467-E (PT)
Title: Mould for a container blow moulding machine and method of producing containers using one such mould
IPC: B29C49/54
Filed: 2005-10-27
Abstract: A mold for a machine which is used for the blow molding of containers from performs. The inventive mold includes a wall defining a cavity that is intended to receive a preform. In addition, the mold includes at least one mold insert which is equipped with a lug and which is mounted such that it can move in relation to the wall by means of a cam system, between: an out position in which the lug projects out at least partially from the wall into the cavity, and a retracted position in which the lug is retracted into the wall. The invention also relates to a method of producing a container by means of blow molding using one such mold.
Patent PT-1728571-E (PT)
Title: Insulated feeder head and method of making same
Inventor: STOECKLEIN ROLF
IPC: B22C9/08
Filed: 2006-06-02
Abstract: An insulating feed unit for use in casting, comprises hollow ceramic spheres with a density of less than 0.3 g/cm3, a hardened binding agent, and fibre material. The unit is produced by mixing the spheres, the binding agent and the fibre material, then forming the mixture and hardening it.
Patent PT-1902409-E (PT)
Title: Silicon chip token and method for making same
Inventor: CHAPET PIERRE
IPC: G06K19/04
Filed: 2006-06-30
Abstract: A generally disc-shaped token of the type having a body produced by multiple injection of plastic material and method of fabricating the same, which includes a core produced by a first injection of plastic material and having a central portion defining the central portion of the body of the token and a peripheral portion with radial projections defining at least part of the edge of the body of the token. The core incorporates an insert including a contactless electronic microchip identification device buried in the central portion during the first injection and retained at its periphery by projections or fingers attached to the injection mold and defining openings in the core. The body of the token includes a covering layer produced by a second injection of plastic material around the peripheral portion of the core to produce in conjunction with the core the whole of the edge and the annular peripheral portion of the body of the token. A decorated label is fixed to each face of the token. The token may be used as a gaming chip or a casino chip.
Patent PT-1884386-E (PT)
Title: Actuating system for a covering canvas
Inventor: AMATO DAVIDE
IPC: B60J7/06
Filed: 2007-07-24
Abstract: It is described an actuating system for a canvas (22) for covering containers of vehicles or fixed containers for waste materials. The canvas is hauled by one or more cable loops (18) set in motion by drive pulleys (16) that transfer to them the motion necessary to move the canvas (22).  The system comprises a bellows-like frame adapted to fold the canvas.
Patent PT-2274412-E (PT)
Title: An apparatus and a method for continuous thermal hydrolysis of biological material
Inventor: HOEJSGAARD SOEREN JOHANNES
IPC: C02F1/02
Filed: 2009-03-31
Abstract: A method for performing continuous thermal hydrolysis of sludge by feeding the sludge into a tube reactor subsequently elevating the temperature and pressure in the reactor. The sludge is cooled by introducing water into the sludge instead of cooling the sludge with a heat exchanger or a similar unit.
Patent PT-2468218-E (PT)
Title: Medical restriction device for hollow organs of a body
Inventor: SZEWCZYK TOMASZ
IPC: A61F5/00
Filed: 2010-12-23
Abstract: The device (1) has an elongate flexible element (2) having two ends (4, 6), and a locking unit (8) circularly locking the flexible element in a predetermined diameter position. A tip (10) includes a reinforcing core (14) that is made up of rigid material, and an opening (18) is provided at one of the ends as part of the locking unit. The tip is inserted with the end of the flexible member into the opening at the other end for locking the locking unit. The tip is fixedly connected with the former end and separated after locking the flexible member by the locking unit. The elongate member consists of a small extent stretchable material. The reinforcing core comprises metal or hard plastic material. The device is made of a transparent or colored material i.e. medical grade silicone.
Patent PT-697076-E (PT)
Inventor: CLUCAS DONALD MURRAY
IPC: F16H23/00
Filed: 1994-05-05
Abstract: A wobble yoke mechanism for converting reciprocating motion to rotary motion (or vice versa) in which each of two yokes (4) are connected to beams (3) by bearings (10, 10', 15, 15') having only one degree of freedom. The two yokes are 90 DEG  out of phase. An eccentric bearing (15), also having only one degree of freedom, is fitted to or about the nutating shaft (16) and is connected to one end of each of the yokes (3). All the axes of the pairs of bearings pass through a central pivot point (5). The axes of the pistons need not be straight nor need they be parallel with the axis of the crankshaft (12).
Patent PT-699199-E (PT)
Inventor: SATAKE KUNIO
IPC: A61P25/06
Filed: 1994-05-13
Abstract: PCT No. PCT/JP94/00781 Sec. 371 Date Nov. 20, 1995 Sec. 102(e) Date Nov. 20, 1995 PCT Filed May 13, 1994 PCT Pub. No. WO94/26740 PCT Pub. Date Nov. 24, 1994Compounds useful in the treatment of inflammatory disorders, central nervous system disorders and other disorders of the formula I and the pharmaceutically-acceptable salts thereof;    <IMAGE>  (I)  wherein R is C1-C6 alkyl; X is C1-C6 alkyl having one or more substituents which include at least one heteroatom; Ar1 and Ar2 are each, independently, aryl optionally substituted by one C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkylthio, halogen, cyano, nitro, phenoxy, mono C1-C6 alkylamino, di C1-C6 alkylamino, halosubstituted C1-C6 alkyl, or halosubstituted C1-C6 alkoxy; Y is hydrogen, C1-C6 alkyl, C2-C6 alkenyl, C3-C8 cycloalkyl, Z-(CH2)p-, or W-(CH2)m-CHR2-(CH2)n-NR1CO- wherein Y is at the 4-, 5- or 6-position on the quinuclidine ring; R1 is hydrogen, C1-C6 alkyl, benzyl or -(CH2)r-W; R2 is hydrogen or C1-C6 alkyl which may be substituted by one hydroxy, amino, methylthio, methylmercapto, benzyl, 4-hydroxybenzyl, 3-indolylmethyl or -(CH2)r-W; R1 may form a ring with R2; Z is C1-C6 alkoxy, -CONR4R5, -CO2R4, -CHR4OR5, -CHR4NR5R6, -COR4, -CONR4OR5 or optionally substituted aryl; each W is independently cyano, hydroxymethyl, C2-C6 alkoxymethyl, aminomethyl, mono C1-C6 alkylaminomethyl, di C1-C6 alkylaminomethyl, carboxyl, carbamoyl or C1-C6 alkoxycarbonyl; R4, R5 and R6 are independently hydrogen, C1-C6 alkyl, C1-C6 alkoxy, C3-C8 cycloalkyl or an optionally substituted aryl or heterocyclic group; p is 0 to 6; and m, n and r are each, independently, 0 to 3.
Patent PT-818992-E (PT)
Inventor: GHANTA SAMBASIVA RAO
IPC: A61K9/00
Filed: 1994-08-09
Abstract: This disclosure is directed to preparation of individual taste-masked, high bioavailability, high payload, microcapsules by microencapsulation of water-insoluble NSAID drug materials in the substantial absence of microcapsule agglomerates. These taste-masked microcapsules contain a high payload, e.g., about 83+wt. % of said NSAID drug material having high bioavailability and can then be formulated into chewable tablets and liquid aqueous suspensions for medicinal use. Both cellulose acetate phthalate and gelatin are the microencapsulating polymer wall material. Control of pH, controlled addition of a Hofmeister (lyotropic) salt, microencapsulation of the water-insoluble NSAID medicament with a liquid phase of both cellulose acetate phthalate and gelatin microencapsulating material and the subsequent insolubilization of said liquid encapsulating material after it is wrapped around the medicament core with dilute acid are important process parameters to achieving the proper individual microcapsules to obtain highly bioavailability taste-masked, water-insoluble NSAID drug materials, esp., naproxen and ibuprofen, by microencapsulation alone.
Patent PT-724547-E (PT)
Inventor: REUNAMAKI PAULI T
IPC: C03B23/03
Filed: 1994-10-05
Abstract: Glass sheet bending apparatus (20) including lower and upper deformable molds (22,44) having respective mold members (24,46) connected by associated linkages (26,48). An actuating mechanism (154) of the apparatus is constructed so as to move the linkages (26,48) to perform the bending which may be performed by moving the deformable molds (22,44) toward each other during the bending. <IMAGE>
Patent PT-779931-E (PT)
Inventor: WURM FLORIAN M
IPC: C12N15/87
Filed: 1995-08-31
Abstract: A method is provided for calcium phosphate transfection of a eukaryotic host cell wherein particles comprising calcium phosphate and a desired nucleic acid are grown to an optimal size and then contacted with the host cell under conditions that substantially reduce the particle growth rate and allow the host cell to take up the particles to form a transfected cell.
Patent PT-987268-E (PT)
Inventor: HOFLE GERHARD
IPC: A61K31/425
Filed: 1998-08-24
Abstract: The invention concerns epothilone A-N-oxide of the following formula:   <CHEM>   Further, the invention concerns epothilone B-N-oxide of the following formula: <CHEM>
Patent PT-874214-E (PT)
Inventor: DELMAS PHILIPPE
IPC: E02D33/00
Filed: 1998-04-17
Abstract: Civil engineering works such as embankment (14) which are built on a site (2) subject to subsidence (4) may be protected by two carpets (12,10) with a layer of earth (11) between them. The upper layer (12) is stronger than the lower layer (10). The lower carpet (10) has two sets of wires in it whose continuity is electrically detected. The first set is broken on initial subsidence due to the calculated weight of the earth layer (11) and the second set breaks on more serious subsidence when the stronger upper carpet (12) deforms and adds to the weight of the earth layer (11). Both carpets are made from materials which will resist corrosion or other degradation.
Patent PT-986403-E (PT)
Inventor: VALENTINO STELLA J
IPC: A61K9/00
Filed: 1998-06-12
Abstract: The present invention is drawn to pharmaceutical composition comprising cyclodextrin and a pharmaceutically active agent or prodrug, wherein the cyclodextrin is present at less than 75% equimolar amounts of the above agent or prodrug. The present invention is further drawn to a method of extending the shelf-life of a pharmaceutically active agent or prodrug by adding one or more cyclodextrins a less than 75% equimolar amounts to said pharmaceutically active agent or prodrug.
Patent PT-994996-E (PT)
Inventor: WARSHAVIAK JEHUDA T
IPC: E05B1/00
Filed: 1998-07-05
Abstract: This invention discloses a handle arranged for driving operation of an axle about an operation axis thereof, the handle including a first element operatively associated with the axle and extending in a first plane perpendicular to the operation axis; and a second element mounted onto the first element and being pivotably mounted with respect to the axle about a second axis lying in the first plane, the second element being arranged with respect to the operation axis so as to be not centered about the axis.
Patent PT-994889-E (PT)
Inventor: DIAGO JOSE
IPC: A61P31/04
Filed: 1998-07-06
Abstract: Erythromycin A oxime in the form of a hemihydrate.
Patent PT-1042771-E (PT)
Inventor: LANE STEPHEN ERNEST
IPC: H01H51/22
Filed: 1998-12-15
Abstract: An electromagnetic actuator for a circuit breaker having a pair of relatively moveable contacts is disclosed. The actuator includes primary actuator coupled to at least one of the contacts by a link mechanism operable to provide closing and holding forces to the contacts of the circuit breaker and a secondary, faster acting actuator which, on tripping thereof, provides sufficient force to at least initiate opening of the contacts by the configuration of the link mechanism. The secondary actuator includes a stored energy latch which has a permanent magnet flux circuit for providing a holding force and a coil connected to receive a trigger signal to overcome the permanent magnet flux to trip the latch.
Patent PT-1071692-E (PT)
Inventor: YVIN JEAN-CLAUDE
IPC: C07H3/06
Filed: 1999-04-13
Abstract: The invention concerns a method for preparing Laminaribiose comprising a step for glycoside binding between a donor and an acceptor of glycosyl. The invention is characterized in that the glycosyl donor is in pyranose form and corresponds to formula (II); the glycosyl acceptor is in furanose form and corresponds to formula (III); said binding step is performed in solution in an anhydrous organic solvent, at a temperature ranging between -80° C. and 40° C., for a time interval ranging between 1 minute and 8 hours, in the presence of a suitable promoter.</PTEXT>
Patent SG-41290-G (SG)
Title: Antiarrhythmic medicament preparation
IPC: A61K31/18
Filed: 1990-06-11
Abstract: A process is provided for preventing or ameliorating arrhythmia by administering to mammals, including man, an effective dose of d-sotalol to lengthen the action potential duration of cardiac cell without blockade of beta-adrenergic receptor sites.
Patent IE-34868-L (IE)
Title: Temporary supports for transfer printing
IPC: B41M5/385
Filed: 1971-01-12
Abstract: 1334114 Transfer printing process CIBAGEIGY AG 13 Jan 1971 [16 Jan 1970] 1712/71 Heading D1B [Also in Division C4] Synthetic textile materials e.g. polyesters and polyamides are printed using transfer sheets carrying dyestuffs of the general formula: wherein ring A is aromatic or saturated, R 1 is H or C 1 -C 6 alkyl, R 2 is H or C 1 -C 6 alkyl, Y is H, Cl, Br or methoxy, R 1 ' is H or C 1 -C 6 alkyl, R 2 ' is C 1 -C 6 alkyl and n is 1 or 2 with the proviso that when Y is hydrogen then the alkyl groups present must have at least 3 carbon atoms, and optionally other sublimable dyestuffs and/or optical brighteners. The transfer sheets may be paper or regenerated cellulose.
[GB1334114A]
Patent IE-33717-L (IE)
Title: Subdividing of a semiconductor wafer
IPC: H01L21/301
Filed: 1970-02-05
Abstract: 1297561 Blasting GENERAL ELECTRIC CO 10 Feb 1970 [19 Feb 1969] 6435/70 Heading B3D [Also in Divisions B5 and H1] Scribe lines forming fraction loci of a wafer of semi-conductor material to be subdivided into pellets are formed by sand blasting.
[GB1297561A]