baber/WOPTO huggingface dataset:
Patent EP-0538318-A1 (EP)
Title: Production de proteines de membrane externe chez des bacteries gram positif et recuperation des epitodes de protection
Inventor: SARVAS MATTI
IPC: C07K14/195
Filed: 1991-07-05
Abstract: L'invention décrit un procédé de production de protéines de membrane externe clonées à partir de bactéries pathogènes Gram négatif. L'invention décrit également un procédé pour renaturer les protéines de membrane externe clonées ainsi produites pour que lesdites protéines clonées retrouvent des épitodes immunologiquement actifs et capables de promouvoir, chez les mammifères et d'autres animaux, la production d'anticorps possédant des qualités bactéricides et pouvant créer une protection contre des infections causées par des bactéries pathogènes Gram négatif. Selon le procédé décrit, l'ADN codant pour les protéines de membrane externe, obtenues à partir de bactéries Gram négatif, connues pour être pathogènes chez les hommes et les animaux, est exprimé dans un hôte bactérien Gram positif. Les protéines de membrane externe recombinées ou clonées ainsi produites sont ensuite renaturées pour qu'elles retrouvent des épitodes biologiquement et immunologiquement actifs et capables de promouvoir, chez les animaux et les hommes, la production d'anticorps; les anticorps sont bactéricides et ils protègent les animaux et les hommes contre des infections causées par les bactéries pathogènes Gram négatif à partir desquelles on a dérivé le gène codant pour les protéines de membrane externe clonées. Le procédé selon l'invention est utilisé, par exemple, pour produire la protéine de membrane externe, de la classe 1, à partir de Meisseria meningitidis, la protéine de membrane externe, de la classe 3, à partir de Meisseria meningitidis, et la protéine de surface externe OmpA à partir de Escherichia Coli.
Patent EP-0532704-A1 (EP)
Inventor: RZEDZIAN RICHARD
IPC: G01R33/421
Filed: 1991-06-06
Abstract: Blindage HF pour RMN ne laissant pas passer l'énergie HF mais permettant à des signaux de fréquence audio tels que ceux d'une bobien à gradient de pénétrer dans une région d'examen. La surface du blindage se compose d'une couche extérieure conductrice (43) divisée par des canaux gravés (28). Lesdits canaux gravés (28) définissent des zones en forme de bandes circonférentielles (30) au niveau des bords des parois du cylindre ainsi que des zones en forme de bandes longitudinales (32) au niveau de la partie centrale des parois du cylindre. Des régions de transition (31) sont ménagéés là où les zones longitudinales et circonférentielles se rencontrent. Un conducteur auxiliaire est connecté au blindage HF. Le conducteur fait office de couplage passe-haut.
Patent EP-0540673-A1 (EP)
Title: Acetylene derivatives having lipoxygenase inhibitory activity.
Inventor: BROOKS DEE W
IPC: C07D213/40
Filed: 1991-07-11
Abstract: Compounds of the structure (I) where p and q are zero or one, but cannot both be the same, M is a pharmaceutically acceptable cation or a metabolically cleavable group, B is a valence bond or a straight or branched alkylene group, R is alkyl, cycloalkyl or -NR<1>R<2>, where R<1> and R<2> are hydrogen, alkyl, cycloalkyl or alkanoyl, and A is optionally substituted carbocyclic aryl, furyl, benzol[b]furyl, thienyl, or benzol[b]thienyl are potent inhibitors of lipoxygenase enzymes and thus inhibit the biosynthesis of leukotrienes. These compounds are useful in the treatment or amelioration of allergic and inflammatory disease states.
Patent EP-0552178-A1 (EP)
Title: Modified ribozymes.
Inventor: ECKSTEIN FRITZ
IPC: A61K38/00
Filed: 1991-09-23
Abstract: The present invention refers to an RNA molecule with catalytic activity comprising at least one modified nucleoside, wherein the hydroxy group at the 2'-position of the ribose sugar is replaced by a modifier group, selected from halo, sulfhydryl, azido, amino, monosubstituted amino and disubstituted amino groups, a process for the preparation of modified RNA molecules and the use of modified RNA molecules as therapeutic agents and biocatalysts.
Patent EP-0558542-A1 (EP)
Title: A stapling machine.
Inventor: ZIGLIOLI ANDREA
IPC: B25C5/16
Filed: 1991-11-19
Abstract: PCT No. PCT/GB91/02045 Sec. 371 Date Oct. 4, 1993 Sec. 102(e) Date Oct. 4, 1993 PCT Filed Nov. 19, 1991 PCT Pub. No. WO92/08579 PCT Pub. Date May 29, 1992.A stapling machine is provided which has markings on part of a constant tension spring visible from the exterior of the machine to provide an indication when the supply of staples within the machine is exhausted. The constant tension spring moves the pusher, and markings are present on part of the constant tension spring which becomes visible in a window provided for that purpose.
Patent EP-0502189-A1 (EP)
Title: Safety hand pump.
Inventor: WILSON ROBERT G
IPC: B67D7/60
Filed: 1991-09-25
Abstract: This invention is a small hand piston type pump design to pump small quanity of flammable liquids safely from a drum. The pump has a grounding clip, and a bonding clip attached and a metal bung adapter to ensure that static build up during the pumping process is adequately grounded from not only the pump but the vessel into which the liquid is being pumped and the drum. The pump also contains a flame arrestor in the spout and a check ball and a strainer in the pickup tube to ensure that a fire within the pump will not extend into the drum and a strainer in the pickup tube to further arrest any flames. The pump is made out of carbon steel, glass and teflon so that the parts have good chemical resitance and are long lasting. The pump has a sealing device design for longjevity. This sealing device has a packing gland whose edges are beveled. It fits into a conically channel between the packing head and packing nut and when the packing nut is tighten the packing gland is forced towards the shaft.
Patent EP-0592440-A1 (EP)
Inventor: NOSCO DENNIS L
IPC: C07C239/08
Filed: 1991-10-25
Abstract: The present invention relates to novel technetium-99m complexes and to methods of preparing the complexes. The present invention further relates to a radiopharmaceutical compositions comprising the complexes, to the use of the compositions for examining the renal function, and to a kit for preparing such compositions.
Patent EP-0503436-A1 (EP)
Inventor: KNUEPPEL PETER C
IPC: C07D251/22
Filed: 1992-03-02
Abstract: Acrylic acid esters of the general formula I 
<IMAGE>
 in which 
 
  R<1> represents alkyl, 
  R<2> represents dialkylamino or a radical -O-R<5>, 
  X represents oxygen, sulphur or a radical 
<IMAGE>
 
  R<3> represents hydrogen, alkyl or alkoxy, 
  R<4> represents optionally substituted aryl or heteroaryl, 
  R<5> represents hydrogen, alkyl or optionally substituted aralkyl, 
  R<6> represents hydrogen, alkyl or in each case optionally substituted aralkyl or aryl, and 
  Y represents a direct bond, oxygen or in each case one of the following groups
 -CH2-; -CH=CH- or -C IDENTICAL C- 
 and a process for their preparation. The acrylic acid esters of the formula I are used for the preparation of pesticides.
Patent EP-0513887-A1 (EP)
Inventor: PARENTI MASSIMO
IPC: C07J41/00
Filed: 1992-04-16
Abstract: The N-alkyl-tauroursodeoxycholic acids of formula (I) and their pharmaceutically acceptable derivatives are useful in the therapy of hepatic diseases and troubles. 
     For the preparation of these acids a conjugation reaction is effected between a mixed anhydride of ursodeoxycholic acid and alkyltaurine, the acide being then obtained by percolation through two columns respectively containing a strong cationic resin in H⁺ form and a weakly anionic resin in OH⁻ form.
Patent EP-0505055-A1 (EP)
Inventor: HERRINGTON FOX JOHN
IPC: B31B19/90
Filed: 1992-03-05
Abstract: A method of making an end stop for a slider of a fastener structure for a thermoplastic bag. The fastener structure comprises a pair of flexible plastic strips adapted to be connected to the walls of the bag (B) and having reclosable interlocking male and female profile elements (16,17) on the respective strips (14,15) and a slider (10) straddling the strips for opening and closing them. The method comprises clamping together a pair of the flexible plastic strips between clamps (40,41) at a seal area in the region intended to form an end of the strips, the clamps (40a,40b) having pockets (41a,41b) therein adjacent the profile elements at the seal area. The profile elements are severed and heated at the seal area with a heated knife (45) to transform the severed ends of the profile elements into molten material; the molten material is pressed into the pockets in the clamps (40,41) with the heated knife (45) thereby increasing the thickness of an area of the strips adjacent the seal area to provide a protruding end stop for preventing movement of the slider past the ends of the bag (30).
Patent EP-0509815-A1 (EP)
Inventor: KRAMER FRANK
IPC: A61B17/068
Filed: 1992-04-16
Abstract: A surgical staple is used in joining the skin or fascia of a patient, and is especially desired to be used with mesh placed over a cut organ, such as the kidney. The staple is adapted to be formed about a central anvil and former. The configuration of the staple is such that at initial contact the points of the staple are formed at acute angles to the central portion of the staple. In this fashion, upon forming, a modified "B" shape is derived. This configuration has proven useful to reduce rotation of the staple when emplaced over mesh.
Patent EP-0511781-A1 (EP)
Inventor: D HOLLANDER OLIVIER JULES LUDO
IPC: B65D19/06
Filed: 1992-04-23
Abstract: A foldable intermediate bulk container with a preferred capacity of about 1000 litres, capable of being stacked both in its erected position and in its folded position, comprises a rectangular base (10), four walls (21, 22, 23, 24) and a lid (35, 36) which are all interconnected. Each wall is pivotally connected to the base (10), at least three of them at different heights from the support (17) of the base, ascending by at least one wall thickness. It is preferably adapted for liquid or free-flowing powder. The base (10) may incorporate the function of a pallet into the structure of the container and may include means for facilitating emptying the container. The container may use an inner pocket (20) for the liquid or powder.
Patent EP-0550947-A1 (EP)
Inventor: LEE YEONG DUH
IPC: B05B15/06
Filed: 1992-05-06
Abstract: For connecting an air compressor to a pneumatic tool, a revolvable quick coupling comprising a first air pipe connector (12) revolvably secured to an intermediate connecting member (13) by a ball bearing means (111) and connected to an air output pipe of an air compressor, a second air pipe connector (16) secured to said intermediate connecting member by a front socket (15), a retainer (152), an inner socket (14), a seal ring (141), a stepped metal element (133) and a spring means for connecting to an air input pipe of a pneumatic tool. Pressing on the retainer causes the second air pipe connector to disconnect from the front socket and simultaneously causes said seal ring to seal the air passage inside the coupling. Rotating the pneumatic tool causes the second air pipe connector to rotate on the first air pipe connector without twisting the air output pipe of the air compressor.
Patent EP-0579880-A1 (EP)
Inventor: YOU CHIN-SAN
IPC: A63B49/12
Filed: 1992-07-22
Abstract: There is disclosed a method of making a game racket frame which comprises the use of a tubular body of aluminium alloy consistent with a shape of a racket frame (10). An annular recess (20) is provided respectively at the mid-point of the left-hand half of the head frame (121) and at the mid-point of the right-hand half of the head frame. The annular recess (20) is coated with adhesive resin. The tubular body is placed in a moulding tool (30) comprising a mould cavity (34) having an annular ring which is located at a position corresponding to the annular recess (20) of the tubular body and which has a shape corresponding to that of the annular recess (20) of the tubular body and a size slightly larger than that of the annular recess (20) of the tubular body. Molten plastics material is injected into the mould cavity (34) under pressure and heat. Upon completion of the curing of the plastic material, the racket frame is removed from the moulding tool. The racket frame so made is provided with weight-balancing pieces (16, 18) fastened securely to the head frame (12) of the racket (10).
Patent EP-0537059-A1 (EP)
Inventor: JOURNEE MAURICE
IPC: B60S1/34
Filed: 1992-10-05
Abstract: The invention proposes a windscreen wiper (14) of the type comprising a drive head (24) of a windscreen wiper arm (26) which is driven in a reciprocating wiping movement by two connecting rods (16, 18) the ends (20, 22) of which are articulated onto the drive head (24) about two substantially parallel pins (28, 30), characterised in that the articulation pins (28, 30) are arranged in a housing (32) of the drive head (24) which is laterally bounded by a wall (34) which comprises at least one adjusting stop (42) which projects transversely out of the plane of the wall (34, 36) in order to interact with a surface portion (40) facing one of the connecting rods (16) in order to define a rest position of the drive head (24). <IMAGE>
Patent EP-0524153-A1 (EP)
Title: Washing brush for washing rollers for motor vehicle automatic washing systems
Inventor: FAVAGROSSA FRANCESCO
IPC: A46B7/10
Filed: 1992-01-21
Abstract: A washing brush for motor vehicle automatic washing system washing rollers comprises a plurality of plate-like elements (1) including sets of bristles (20), which can be wound about a supporting roller and arranged near one another in an axial direction, each plate-like element (1) including a plurality of cylindric seats (3) for housing therein evenly distributed bristle sets (20). The main feature of the invention is that each plate-like element (1) is further provided, at an end portion thereof, with a recessed portion (18) devoid of cylindric seats therein can be engaged a middle projection (11) having cylindric seats (3) and provided on the other end portion of the plate-like element (1), at least a removable coupling element (17) being moreover provided for coupling the mentioned end portions (11,18).
Patent EP-0517682-A1 (EP)
Inventor: NIADA GIANANDREA
IPC: A47K5/12
Filed: 1992-06-04
Abstract: There is described herein a liquid soap dispenser (1), improved in that it is provided with a push-operated dispensing actuation lever (4), mounted on the front lid (2) portion of the box comprising said dispenser. Said lid is pivotally connected at a position close to the bottom of the fixed portion, fastened to a wall (3), in order to open completely at 180° relative to said fixed portion, for the purpose of providing a maximum ease of access during replacement of the supply cartridge and for the most convenient positioning of the dispensing arrangement within said dispenser. In addition, the pressure member (10) acting against the dispensing arrangement flexible wall is preferably comprised of an oscillating member, connected or integral with the actuating lever (4), in order to conform automatically to said flexible wall, by being maintained as much as possible in a parallel position thereto during the approaching motion thereof.
Patent EP-0606205-A1 (EP)
Inventor: TERHO MIKKO
IPC: G06F13/00
Filed: 1991-11-26
Abstract: Afin de relier un ordinateur (4) à un téléphone analogique individuel (1), on équipe l'ordinateur d'une carte de modem (5) comprenant une fonction de modem, un adaptateur de bus audio téléphonique, une porte adaptée au bus de commmande numérique du téléphone, des connexions destinées aux bus audio et de commande, et du logiciel, la carte de modem pouvant convertir les instructions de modem numérique en instructions téléphoniques et vice-versa. Le téléphone (1) est de préférence un téléphone cellulaire et l'ordinateur (4) peut être un ordinateur personnel portable. Il est aussi possible de faire en sorte que la carte de modem soit reliée à d'autres équipements de réseau téléphonique fixes tels qu'un terminal de télécopieur.
Patent EP-0556340-A1 (EP)
Inventor: TEASDALE ROBERT D
IPC: C12N5/00
Filed: 1991-11-04
Abstract: On décrit un milieu de culture aqueux pour la culture tissulaire de plantes, comprenant une concentration efficace d'un point de vue nutritif d'azote réduit, de préférence sous forme d'un acide aminé tel que l'arginine utilisé en une quantité comprise entre 1,0 et 5,0 mM, et ne comprenant pas plus de 1,5 mM de NH4+. Un composé de phosphore en une concentration d'au moins 2,5 mM mesurée sous forme de phosphate est aussi compris. Un agent de chélation, tel que l'ATDE, et un composé de fer présentant un excédent molaire par rapport à la concentration de l'agent de chélation sont utilisés pour réguler les concentrations ioniques bivalentes. Des ions de potassium sont maintenus en une concentration inférieure à 14 mM. Des milieux contenant des ions d'ammonium en une concentration inférieure à 1,5 mM, en combinaison avec une alimentation en azote réduit sous forme d'arginine, avec de faibles niveaux de potassium, se sont révélés utiles en tant que milieux de croissance organisée, en particulier utilisés avec des plantes conifères.
Patent EP-0569393-A1 (EP)
Title: Derivatives of dicarboxylic acids having six to twelve carbon atoms and use of these derivatives and dicarboxylic acids alone in the preparation of pharmaceutical compositions for enteral and parenteral nutrition.
Inventor: CASTAGNETO MARCO
IPC: A23L1/30
Filed: 1992-01-28
Abstract: Linear chain dicarboxylic acids having 6 to 12 carbon atoms and novel derivatives thereof, such as amides with natural amino acids and esters with biliary acids, are useful in the formulation of pharmaceutical compositions suitable for enteral and parenteral administration.
Patent EP-0566636-A1 (EP)
Inventor: MOELLER NIELS THOR
IPC: H01H19/11
Filed: 1991-12-17
Abstract: Générateur d'impulsions électro-mécaniques dont le mode de fonctionnement est purement mécanique et s'utilisant dans un équipement micro-électronique, par exemple pour le réglage du volume dans des prothèses auditives; ledit générateur d'impulsions est constitué par un boîtier formé par une partie de base fixe (7) dans laquelle un axe (3) est monté fixe et une roue de synchronisation (1) est montée rotative autour de l'axe, ladite roue de synchronisation se présentant sous la forme d'un cylindre ouvert vers le bas, en liaison fixe avec un boîtier formant une poignée extérieure. La surface intérieure du cylindre formée par la roue de synchronisation (1) est pourvue de rainures (12) venant en prise avec la saillie (13) d'un support circulaire (5) monté rotatif autour de l'axe (3). Un ressort de contact en forme de U (6) possède des éléments (6', 6'') sur lesquels s'exerce individuellement un mouvement oscillant, respectivement entre les paires de contact A-B-C et A-D-E, créé par la rotation de la roue de synchronisation (1) dans l'un ou l'autre sens, par l'intermédiaire du support qui ne peut se déplacer que sur une section circulaire prédéterminée, afin de produire des trains d'impulsions numériques. Un dispositif de blocage (4, 10, 15) empêche le support (5) de se déplacer au-delà de la section circulaire prédéterminée et provoque l'engagement continu de la saillie (13) dans les rainures (12) sous l'effet de la rotation de la roue de synchronisation (1).
Patent EP-0529086-A1 (EP)
Inventor: EJIMA DAISUKE CENTRAL RES LAB
IPC: A61K38/00
Filed: 1992-02-25
Abstract: L'invention se rapporte: à un procédé qui sert à purifier un facteur de différenciation de lymphocites B (FDLB) humain en soumettant à une oxydation et à un repliement la forme réduite du FDLB humain, qu'on a préparé en cultivant un micro-organisme contenant un gène de FDLB humain intégré à lui et en solubilisant le produit de culture à l'aide d'hydrochlorure de guanidine, et dans lequel le produit d'oxydation est traité par chromatographie par filtration sur gel dans des conditions où la concentration d'hydrochlorure de guanidine est de 4 à 7 M, pour obtenir un FDLB humain possédant la liaison de disulphure intramoléculaire et la structure stéréochimique d'un FDLB humain naturel; à un procédé qui sert à purifier un FDLB humain en retirant un solvant organique de la solution du FDLB humain contenant ledit solvant, et dans lequel la solution est passée à travers une colonne de chromatographie par filtration sur gel équilibrée au moyen d'un solvant organique pour permettre l'élution selon le programme du gradient linéaire ou échelonné, pour obtenir un monomère de FDLB humain naturel; ainsi qu'à un procédé qui sert à purifier un FDLB humain et qui comprend les étapes de chromatographie par échange ionique et de chromatographie liquide à haute performance en phase inverse, appliquées dans les procédés mentionnés ci-dessus. Ces procédés permettent d'éliminer des impuretés dérivées du micro-organisme et des analogues de FDLB humain, et le FDLB humain naturel ainsi obtenu possède un niveau de pureté élevé de sorte qu'il peut être utilisé comme médicament.
Patent EP-0569516-A1 (EP)
Title: Cargo rail system for an aircraft.
Inventor: RAWDON BLAINE K
IPC: B64D9/00
Filed: 1992-01-27
Abstract: Fixed parallel cargo rails are positioned on the cargo bed floor of an aircraft, spaced sufficiently to fit a pallet snugly therebetween. A plurality of collinear slots arranged along the length of the cargo bed floor are positioned just inboard of each rail. The slots are evenly spaced and oriented lengthwise with respect to the cargo bed floor. A dog extends above the cargo bed floor from each slot and is adapted to engage a notch in the cargo. While engaged, the dog is adapted to move along its slot, thereby moving the pallet lengthwise along the cargo bed floor. The pallet is passed bucket brigade style from one dog to the next. Another aspect of the invention is the employment of movable cargo rails on the cargo ramp. The rails are slidable widthwise across the ramp within mounting slots, thus permitting the spacing between the rails to vary. The result is that loading cargo onto the ramp and aligning it with the fixed cargo rails on the cargo bed floor is made much easier.
Patent EP-0579680-A1 (EP)
Title: Device for the production of defined ionised gases or ionisation products.
Inventor: GOLDSTEIN NAUM
IPC: A61L2/14
Filed: 1992-04-09
Abstract: The invention relates to a device for the production of defined ionised gases or ionisation products. To provide such a device in which the production of harmful by-products is minimised, it is proposed that the device have the following features: a tubular hollow electrode connectable to the gas supply line as an external electrode (3); at least one internal electrode (6) which affects the entire hollow space of the external electrode (3) in the region of its arrangement; a potential difference at the internal electrode (6) and the external electrode (3) of 2 to 3 kV, whereby a potential difference of 1 kV at the most is possible between the internal and external electrodes; and a gas flow rate of under 100 ml/min/mm?2.
Patent EP-0581959-A1 (EP)
Inventor: MOCHIZUKI MANABU
IPC: A61K31/436
Filed: 1992-04-24
Abstract: Sont décrits des composés macrolides tels que le FR-900506 et ses composés apparentés pour la prévention ou le traitement des maladies des yeux, notamment la conjonctivite allergique. Est également décrite une composition renfermant ces composés.
Patent EP-0546197-A1 (EP)
Inventor: NAKAMURA KOSEI FANUC DAI- VIRA
IPC: H02K17/16
Filed: 1992-06-26
Abstract: Un rotor (14) comprend une structure dans laquelle une pluralité de trous (22) traversent la partie phériphérique d'un noyau (20) constitué de fer feuilleté; des tiges conductrices (24) constituées d'aluminium sont passées de force dans les trous (22) et des anneaux d'extremité (26) conducteurs sont fixés aux parties des tiges conductrices qui dépassent des deux côtés du noyau (20) en fer feuilleté; des goupilles fendues (30) sont entrées de force dans les petits trous (32) situés aux deux extrémités des tiges conductrices (24), ce qui maintient fermement les anneaux d'extrémité (26) conducteurs aux deux côtés du noyau (20) en fer feuilleté.