baber/WOPTO huggingface dataset:
Patent MX-2016002208-A (MX)
Title: Binding polypeptides having a mutated scaffold.
Inventor: NORDLING ERIK
IPC: C07K14/31
Filed: 2014-08-28
Abstract: The present disclosure relates to a class of engineered polypeptides and provides a polypeptide comprising the sequence EX2X3X4AX6X7</ sub>EIX10 X11 LPNLX16X17X18QX20 X21AFIX25X26LX28X<s ub>29X30 PX32QSX35X36LLX39E AKKX45X46X47Q. The present disclosure also relates to populations of polypeptide variants based on a common scaffold, each polypeptide in the population comprising the amino acid sequence EX2X3X4AX6X7</ sub>EIX10 X11 LPNLX16X17X18QX20 X21AFIX25X26LX28X<s ub>29X30 PX32QSX35X36LLX39E AKKLX45X46X47Q, and methods for selecting a desired polypeptide having an affinity for a predetermined target from said population.
Patent MX-2016004142-A (MX)
Title: Notch 1 specific sirna molecule.
Inventor: SÖREN SCHREIBER
IPC: A61K31/712
Filed: 2014-09-30
Abstract: The present invention is related to a nucleic acid molecule comprising a double-stranded structure, wherein the double-stranded structure is formed by a first strand and a second strand, wherein the first strand consist of the following nucleotide sequence 5' acGaGcUgGaCcAcUgGuCdTsdT 3', and the second strand consists of the following nucleotide sequence 5' GAcCaGuGgUcCaGcUcGudTsdT 3', wherein a minor nucleotide indicates that the nucleotide is 2'-F modified and an underlined nucleotide indicates that the nucleotide is 2'-0-methyl modified and wherein dTsdT indicates that at the 3' end a dinucleotide is attached consisting of two dT nucletoides, wherein said two dTs are covalently linked through a phosphorothioate bond.
Patent MX-2016006539-A (MX)
Title: Machinery frame for a roller crusher.
Inventor: BURKHARD PETACK
IPC: B02C4/28
Filed: 2016-05-19
Abstract: The present invention relates to a machine frame for a roll crusher that has two side walls and two end walls, where the mentioned end walls accommodate the storage of the rolls. The end walls are split horizontally in the area of the mounting of the rollers, and vertically between the mountings of the upper part. One advantage is that to remove a roller, removal of the respective upper end wall is sufficient. In a preferred embodiment of the invention, the adjacent upper parts of the end walls do not touch. An advantage of this is that tilting of the end wall upper parts among each other or in contact with the side walls is prevented during removal. Furthermore, the gap resulting from the distance between the front wall upper parts in the preferred embodiment would be sealed, with the advantage that no material and dust can exit.
Patent MX-2016007818-A (MX)
Title: Apparatus, system and method for sce.
Inventor: ANAND RAGHAWA PRASAD
IPC: H04W12/04
Filed: 2014-11-20
Abstract: In order for supporting separate ciphering at an MeNB (20) and an SeNB (30), the MeNB (20) derives separate first and second keys (KUPenc-M, KUPenc-S) from a third key (KeNB). The first key (KUPenc-M) is used for confidentially protecting first traffic transmitted over U-Plane between the MeNB (20) and a UE (10). The first key (KUPenc-M) may be the same as current KUPenc or a new key. The second key (KUPenc-S) is used for confidentially protecting second traffic transmitted over the U-Plane between the UE (10) and the SeNB (30). The MeNB (20) sends the second key (KUPenc-S) to the SeNB (30). The UE (10) negotiates with the MeNB (20), and derives the second key (KUPenc-S) based on a result of the negotiation.
Patent MX-2016008049-A (MX)
Title: A conductivity sensor, and a pump comprising such sensor.
Inventor: FREDRIK JOHANSSON
IPC: G01N27/10
Filed: 2014-12-19
Abstract: A conductivity sensor is provided. The sensor comprises at least one electrode (410) being embedded in a cylindrical non-conductive body (420) such that one end (412) of each one of the at least one electrode (410) is exposed to a sample volume (430), wherein the sensor further comprises a support body (440) to which the cylindrical body (420) is engagable with, which support body (440) comprises means (442) for attaching said support body (440) to a frame structure (320) in a fluid tight manner.
Patent MX-2016010134-A (MX)
Title: Medicinal composition comprising diamino heterocyclic carboxamide compound as active ingredient.
Inventor: Tomohiro EGUCHI
IPC: A61K45/00
Filed: 2015-02-03
Abstract: [Problem] To provide: a medicinal composition for treating an AXL-related cancer; in another embodiment, a medicinal composition for treating a cancer with high expression of AXL; and, in still another embodiment, a medicinal composition for treating a cancer that has acquired resistance through activation of AXL against anticancer agent therapy. [Solution] As the results of an examination on compounds having AXL inhibitory effect, the present inventors confirmed that specific diamino heterocyclic carboxamide compounds have AXL inhibitory effect and medicinal compositions comprising such a compound as an active ingredient have therapeutic effect on an AXL-related cancer, on a cancer with high expression of AXL in another embodiment, and on a cancer that has acquired resistance through activation of AXL against anticancer agent therapy in still another embodiment, thereby completing the present invention.
Patent MX-2016013991-A (MX)
Title: Method and system for spatially resolved wettability determination.
Inventor: KATHRYN ELIZABETH WASHBURN
IPC: G01N33/24
Filed: 2015-05-06
Abstract: A method which allows for determining wettability with spatial resolution of porous materials or other materials is provided. The method can provide an absolute method of quantifying wettability, and which is a spatially resolved method. A system for performing the method also is provided.
Patent MX-2017002540-A (MX)
Title: A pharmaceutical composition for silver nanoparticles and use thereof in the treatment of cancer without genotoxic effects.
Inventor: Karla Oyuki JUÁREZ MORENO
IPC: A61K9/00
Filed: 2017-02-27
Abstract: The present invention relates to the use of silver nanoparticles (AgNPs) coated with Polyvinylpyrrolidone (PVP) to prepare a pharmaceutical composition for preventing and/or treating neoplastic diseases, or as an adjuvant to therapy against different types of cancer without genotoxic effects, and a composition for preventing and/or treating neoplastic diseases, or as a coadjuvant to therapy against different types of cancer such as breast, cervix, melanoma, colon, lung, prostate, without limiting it to other types of tumors.
Patent MX-2017002888-A (MX)
Title: Profiles.
Inventor: CASTELLUCCI MICHAEL
IPC: E04B2/78
Filed: 2015-09-07
Abstract: An elongate profile (1) having a first portion (2) and a second portion (3), the first and second portions (2, 3) being joined together at a first joining portion (JP1), the first and second portions (2, 3) being non collinear, the joining portion (JP1) comprising an array of raised or rebated formations(10a), each formation extending across the joining portion (JP1) in a direction which is non-parallel to the principal axis of the profile and flat lands being provided between successive formations in an array (10A) and the pitch (P) between successive formations in an array being from 2 to 20 times, for example from 5 to 15 times, the thickness (G) of the flatlands.
Patent MX-2017005092-A (MX)
Title: Process for packaging a set of stacked lids and packaging device for sets of stacked lids.
Inventor: BRUNO LEONARDO GIUBLIN
IPC: B65B43/34
Filed: 2015-12-03
Abstract: The present invention relates to a process for packaging a set of stacked lids that includes the steps of taking an empty, flattened packaging (12), which includes an entry (25), affixing a vacuum terminal (8) in the immediate vicinity of the entry (25) of the packaging (12) and maintaining this packaging (12) rectilinear; maintaining the vacuum terminal (8) activated, retaining the packaging (12) and producing a stream of air towards the entry (25) of the packaging (12), in such a manner as to open the entry (25) of the packaging (12); maintaining the vacuum terminal (8) activated, retaining the packaging (12), and fitting the entry (25) of the packaging (12) thus opened into a feed opening (5); transferring inside the packaging (12) a set of stacked lids (6), the set of lids (6) being passed through the feed opening (5) and through the entry (25) of the packaging (12) as far as the interior of the packaging (12). The invention also relates to a packaging device for sets of stacked lids.
Patent MX-2017005845-A (MX)
Title: Packet energy transfer power control elements.
Inventor: STEPHEN EAVES
IPC: H04B3/54
Filed: 2015-11-06
Abstract: A digital power system includes at least one electrical power source, at least one power control element, and a digital power receiver electrically coupled with the power control element to receive electrical current therefrom. The power control element includes (i) a power conditioning circuit electrically coupled with the electrical power source and (ii) element controller circuitry electrically coupled with the power conditioning circuit. The element controller circuitry is also configured to control and receive feedback from the power conditioning circuit, to receive a communication/synchronization signal, and to output digital power under packet energy transfer protocol.
Patent MX-2017007390-A (MX)
Title: Use of immune checkpoint inhibitors in central nervous systems neoplasms.
Inventor: VLADIMIR CORIC
IPC: A61K39/395
Filed: 2015-12-16
Abstract: This disclosure provides a method for treating glioma in a subject comprising administering to the subject an anti-Programmed Death-1 (PD-1) antibody. In some embodiments, this invention relates to methods for treating glioma in a subject comprising administering to the subject a combination of an anti-cancer agent which is an anti-Programmed Death-1 (PD-1) antibody and another anti-cancer agent such as an anti-Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4) antibody.
Patent MX-2017008933-A (MX)
Title: Heat-reflective blank and container and method of forming a heat-reflective blank and container.
Inventor: PAUL C HASCHKE
IPC: B32B37/14
Filed: 2017-07-05
Abstract: A method for forming a heat-reflective blank includes laminating at least one thermal film sheet at a predetermined position on a first linerboard sheet such that a laminated sheet is formed, and feeding the laminated sheet into a corrugating machine. The method further includes coupling the laminated sheet to a corrugated medium sheet and a second linerboard sheet such that a corrugated sheet is formed. The corrugated medium sheet is between the first linerboard sheet and the second linerboard sheet and the thermal film sheet is positioned on an outer surface of the corrugated sheet.
Patent MX-2017009927-A (MX)
Title: Cartridge, process cartridge, and image forming apparatus.
Inventor: TAKAHITO UENO
IPC: G03G21/18
Filed: 2016-02-23
Abstract: A technique enabling downsizing of an image forming apparatus is provided. A cleaning unit (13) attachable to and detachable from an apparatus main body of an image forming apparatus (100) that forms an image on a recording material (12) is provided, with this cleaning unit including: a photosensitive drum (1); and a cleaning frame body (14) that supports the photosensitive drum and that includes an opening (14c) through which laser light (3a) for exposing the photosensitive drum can pass, wherein the opening is configured such that a width of the opening in a scanning direction in an irradiation range of the light for exposing the photosensitive drum becomes greater toward a side of the photosensitive drum from a side of a light source of light for exposing the photosensitive drum.
Patent MX-2017010106-A (MX)
Title: Sound damping wallboard and method of constructing a sound damping wallboard.
Inventor: STEPHEN A CUSA
IPC: E04B1/84
Filed: 2016-02-05
Abstract: A sound damping wallboard for installation on an installed wallboard, a sound damping wallboard system, and a method of constructing a sound damping wallboard on a building structure are disclosed. The sound damping wallboard comprises a gypsum layer having a gypsum layer inner surface and a gypsum layer outer surface, a sound damping layer disposed at the gypsum layer inner surface for installation between the gypsum layer and an installed wallboard and having a sound damping layer inner surface, a first encasing layer disposed at the gypsum layer outer surface, and a second encasing layer disposed at the sound damping layer inner surface.
Patent MX-2017012272-A (MX)
Title: Tiotropium inhalation solution for nebulization.
Inventor: ULHAS DHUPPAD
IPC: A61K9/00
Filed: 2016-05-17
Abstract: The present invention relates to a sterile pharmaceutical composition comprising tiotropium or a pharmaceutically acceptable salt thereof, for inhalation via nebulization to a subject (e.g. a human). The invention also relates to a process for preparing the pharmaceutical composition and its use in the treatment of respiratory diseases such as chronic obstructive pulmonary disease (COPD) in a subject.
Patent MX-2017012283-A (MX)
Title: Industrial and hydrocarbon gas liquefaction.
Inventor: COLIN F NIKIFORUK
IPC: F25J1/02
Filed: 2016-03-23
Abstract: A method for liquefaction of industrial gases or gas mixtures (hydrocarbon and/or non-hydrocarbon) uses a modified aqua-ammonia absorption refrigeration system (ARP) that is used to chill the gas or gas mixture during the liquefaction process. The gas may be compressed to above its critical point, and the heat of compression energy may be recovered to provide some or all of the thermal energy required to drive the ARP. The method utilizes a Joule Thomson (JT) adiabatic expansion process which results in no requirement for specialty cryogenic rotating equipment. The aqua-ammonia absorption refrigeration system includes a vapour absorber tower (VAT) which permits the recovery of some or all of the heat of solution and heat of condensation energy in the system when anhydrous ammonia vapour is absorbed into a subcooled lean aqua-ammonia solution. The modified ARP with VAT may achieve operating pressures as low as 10 kPa which results in ammonia gas chiller operating temperatures as low as -71 C.
Patent MX-2017014331-A (MX)
Title: Lighting system having pointer device.
Inventor: STUART C SALTER
IPC: B60Q1/26
Filed: 2017-11-08
Abstract: A lighting system is provided herein. The lighting system includes a spotlight is mounted to a vehicle, a controller for operating the spotlight, and a pointer device for specifying an intended target. The controller aims the spotlight in the direction of the intended target based on input provided by the pointer device.
Patent MX-2017015571-A (MX)
Title: Process and facility for the treatment of livestock waste.
Inventor: GAL LEVIN
IPC: C02F11/04
Filed: 2016-11-01
Abstract: The invention provides an efficient system for treating livestock waste, particularly waste from cattle or pig farming. The new facility and method employ special transfers of slurry streams through ASBR, SBR, and a unique pretreatment reactor, resulting in treated water, quality compost, and biogas.
Patent MX-2018001298-A (MX)
Title: Immunity inducer.
Inventor: FUMIYOSHI OKANO
IPC: C12N15/09
Filed: 2016-08-05
Abstract: The present invention addresses the problem of discovering a novel peptide useful as an active ingredient of a drug for the treatment or prevention of cancer, and providing the use of the polypeptide as an immunity inducer. An immunity inducer containing as an active ingredient (a) a polypeptide comprising amino acids shown by SEQ ID NOS: 35-67 or (b) a polypeptide having from one to several amino acids of a polypeptide of (a) deleted, substituted, or added is useful as a drug for the treatment or prevention of cancer.
Patent MX-2018003196-A (MX)
Title: Anti-pro/latent-myostatin antibodies and uses thereof.
Inventor: GREGORY J CARVEN
IPC: A61K39/395
Filed: 2016-09-15
Abstract: Aspects of the present disclosure relate to antibodies that specifically bind proMyostatin and/or latent Myostatin and uses thereof.
Patent MX-2018003391-A (MX)
Title: Friction end-of-car cushioning assembly.
Inventor: SHAUN RICHMOND
IPC: F16J15/00
Filed: 2018-03-16
Abstract: An assembly that includes a housing with a chamber formed within a bore of the housing. The assembly further includes a center shaft disposed at least partially within the bore of the housing. The chamber includes a backing wedge, a sliding wedge, and a load spring. The sliding wedge is positioned to apply a force onto an angled contact surface of the backing wedge. The sliding wedge is also positioned to apply a frictional force to a rod portion of the center shaft. The load spring is compressed between a contact surface of the chamber and a contact surface of the sliding wedge. The load spring is positioned to apply a compressive force onto the contact surface of sliding wedge toward the angled contact surface of the backing wedge.
Patent MX-2018003984-A (MX)
Title: Steel workpiece with improved surface quality.
Inventor: SASCHA SIKORA
IPC: B23K20/227
Filed: 2015-09-30
Abstract: The invention relates, inter alia, to a steel workpiece (1) having an edge region (2) and a core region (3). The aim of the invention is to devise a steel workpiece (1) which has the highest possible near-surface strength and yet favorable surface properties, in particular a favorable scale behavior during hot rolling. For this purpose, the steel workpiece (1) is softer in the edge region (2) than in the core region (3) and the sum of alloy constituents C, Si, Mn, Cr and N of the steel workpiece (1) is greater than 1.45 wt.-%.
Patent MX-2018004763-A (MX)
Title: Immunoassay to detect cleaved high molecular weight kininogen.
Inventor: Ryan FAUCETTE
IPC: G01N33/68
Filed: 2016-10-19
Abstract: The present disclosure provides immunoassay methods of detecting a cleaved high molecular weight kininogen (HMWK) with high sensitivity and specificity and isolated antibodies that specifically bind cleaved HMWK.
Patent MX-2018005252-A (MX)
Title: Treatment of hepatic steatosis related oligo-ovulation.
Inventor: LOURDES IBÁÑEZ
IPC: A61K31/155
Filed: 2016-10-27
Abstract: The present invention relates to a method and composition for use in treating a condition that benefits from the reduction of hepatic and/or visceral fat, such as polycystic ovary syndrome in adolescent girls or women of childbearing age, involving the useof spironolactone, pioglitazone and metformin.
Patent MX-2018006955-A (MX)
Title: Gene therapy for neurodegenerative disorders.
Inventor: SHIHABUDDIN LAMYA
IPC: C12N15/79
Filed: 2011-11-01
Abstract: Compositions and methods for treating disorders affecting motor function, such as motor function affected by disease or injury to the brain and/or spinal cord, are disclosed. Also disclosed is a self-complementary adeno-associated virus vector for treating motor neuron disorders such as spinal muscular atrophy, amytrophic lateral sclerosis, spinal bulbar muscular atrophy, spinal cerebellar ataxia, primary lateral sclerosis, and traumatic spinal cord injury.
Patent MX-2018008110-A (MX)
Title: Method for deacetylation of biopolymers.
Inventor: CRAIG STEVEN HARRIS
IPC: C08B37/00
Filed: 2016-12-28
Abstract: A method for at least partial deacetylation of a biopolymer comprising acetyl groups, comprising: a1 ) providing a biopolymer comprising acetyl groups; a2) reacting the biopolymer comprising acetyl groups with hydroxylamine (NH2OH) or a salt thereof at a temperature of 100 °C or less for 2-200 hours to form an at least partially deacetylated biopolymer; and a3) recovering the at least partially deacetylated biopolymer.
Patent MX-2018009688-A (MX)
Title: Drug containing carrier into cell for forming immune complex.
Inventor: IGAWA TOMOYUKI
IPC: C12N15/09
Filed: 2014-05-30
Abstract: The inventors of the present invention discovered that the loss, from blood plasma, of antigens containing two or more antigen-binding units is accelerated by forming a large immune complex containing two molecules or more of an antigen-binding molecule (for example an antibody), and an antigen having two or more antigen-binding units (epitopes). Moreover, the inventors discovered that the present invention can be achieved by further accelerating the loss of antigens by using the aforementioned characteristic and by using an antigen-binding molecule exerting ion-dependent antigen-binding activity.
Patent MX-2018016250-A (MX)
Title: Crystalline forms of 4-(5-(4,7-dimethylbenzofuran-2-yl)-1,2,4-oxa diazol-3-yl)benzoic acid and processes for their preparation.
Inventor: EDWIN ARET
IPC: C07D407/04
Filed: 2017-06-16
Abstract: The present invention pertains generally to the field of therapeutic compounds, and more specifically to crystalline forms of 4-(5-(4,7-dimethylbenzofuran-2-yl)-1,2,4-oxadiazol-3-yl)benzoic acid (referred to herein as "BHBA-001"), which, inter alia, is a (selective) retinoic acid receptor beta (RARß) (e.g., RARß2) agonist. The present invention also pertains to pharmaceutical compositions comprising such crystalline forms, and the use of such crystalline forms and compositions, both in vitro and in vivo, to (selectively) activate RARß (e.g., RARß2), to cause or promote neurite development, neurite outgrowth, and/or neurite regeneration, and in the treatment of diseases and conditions that are mediated by RARß (e.g., RARß2), that are ameliorated by the activation of RARß (e.g., RARß2), etc., including, e.g., neurological injuries such as spinal cord injuries.
Patent MX-2019002283-A (MX)
Title: Processes for making masterbatches of rubber and silica.
Inventor: XUAN FU
IPC: C08L21/00
Filed: 2017-08-31
Abstract: A process is provided for making a silica masterbatch that contains silica and solution-made rubber. The silica masterbatch has physical properties similar to those found in a comparable dry-mixed composition, but the silica masterbatch can be incorporated more easily and less expensively into tires and other rubber products than the dry-mixed composition, A process is also provided for making a masterbatch of silica, a solution-made rubber and an emulsion-made rubber.
Patent MX-2019006741-A (MX)
Title: Plant health effect of purpureocillium lilacinum.
Inventor: MARC ANDRE RIST
IPC: A01N63/30
Filed: 2017-12-08
Abstract: The present invention relates to a method for promoting or improving plant health and/or plant growth of agricultural plants wherein the plants, the plant propagules, the seed of the plants and/or the locus where the plants are growing or are intended to grow are treated with an effective amount of a composition comprising the fungus Purpureocillium lilacinum or spores thereof. Further aspects of the invention relate to uses of a composition comprising the fungus Purpureocillium lilacinum or spores thereof for promoting or improving plant health and/or plant growth.
Patent MX-2019006948-A (MX)
Title: Probiotics for use in the treatment of diverticulosis and diverticular disease.
Inventor: RUGGERO ROSSI
IPC: A61K35/747
Filed: 2017-12-15
Abstract: The present invention relates to the use of probiotics to control the inflammatory process of the colon in subjects with structural modifications of the colon wall, preferably in subjects with diverticulosis, and affected by diverticular disease.