baber/WOPTO huggingface dataset:
Patent WO-2021016132-A1 (WO)
Title: Compositions, methods, kits and systems for cancer treatment and metabolic intervention therapy and other uses
Inventor: LI XIYAN
IPC: A23L33/00
Filed: 2020-07-17
Abstract: The present disclosure provides compositions and methods for treating cancer with nutritionally modified diets and/or dialysis treatment, such as through amino acid depletion of one or more nonessential amino acids. In some aspects, the present disclosure provides compositions and methods for treating obesity with such modified diets and/or dialysis treatment. Furthermore, in some aspects, the present disclosure provides compositions and methods for treating renal disease with such modified diets and/or dialysis treatment.
Patent WO-2021030118-A1 (WO)
Inventor: COHEN MILTON
IPC: A61J1/14
Filed: 2020-08-05
Abstract: A lockable container (100) for securing items or objects, the container including a first element (20), which may include a cylindrical member (26) and a retainer (21) for capturing two or more rotatable rings (30) on the cylindrical member, and a second element (40), which is mateable with the first element, cooperating with the rings to close an open end (41) of the cylindrical member of the first element.
Patent WO-2021034618-A1 (WO)
Title: Device and method for application of cosmetic compositions through a grated end effector
Inventor: BINNER CURT
IPC: A61B5/00
Filed: 2020-08-13
Abstract: A device for applying a composition to a skin of a face includes an end effector having a base portion and a protruding portion extending distally from the base portion. The protruding portion has a distal opening. The device also includes a detector arrangement obtaining image data corresponding to an image of an area of the skin through the distal opening and an applicator arrangement applying the composition to a location within the area. The device further includes a processing arrangement receiving and analyzing the image data to determine whether the applicator is aimed to safely dispense the composition to the area and whether a frexel within the area corresponds to a skin artifact, and directing the applicator to selectively apply the composition to the frexel when the applicator is aimed to safely dispense the composition to the area and the skin artifact is detected from the frexel.
Patent WO-2021061578-A1 (WO)
Title: Polymer compositions with excellent electrical and mechanical properties
Inventor: THAKUR VARUN
IPC: C08L23/16
Filed: 2020-09-21
Abstract: A composition comprising the following: a) a first ethylene/alpha-olefin/non-conjugated polyene interpolymer that has a Mooney Viscosity ≥ 50; b) a second ethylene/alpha-olefin/non-conjugated polyene interpolymer that has a Mooney Viscosity < 50; c) a calcined filler formed from a filler composition comprising a kaolinite.
Patent WO-2021061754-A1 (WO)
Inventor: DONOVAN NEAL
IPC: A61B7/04
Filed: 2020-09-23
Abstract: An electronic stethoscope device can be integrated into a conventional stethoscope to digitize auscultated sounds from the body of a patient. The device can be switched off so that the conventional stethoscope can be used as a standard stethoscope. When the device is switched on, the digitized auscultated sounds can be modified to remove the noise. Such modified sounds can be sent wirelessly from the electronic stethoscope device to a peripheral device that can receive such wireless signals, such as computer, cell phone, or cloud application, where the data can be viewed and manipulated further as desired.
Patent WO-2021062419-A1 (WO)
Title: Nouveaux vecteurs et utilisations associées
Inventor: BURKE JOHN
IPC: C12N15/86
Filed: 2020-09-30
Abstract: L'invention concerne une particule virale comprenant un ARN génomique approprié pour administrer une séquence polynucléotidique d'intérêt (SOI) dans une cellule et/ou un sujet. L'ARN génomique comprend, de l'extrémité 5' à l'extrémité 3' : (a) la SOI remplaçant le R amont, (b) un U5, (c) un site de liaison d'amorce (PBS), (d) un signal d'encapsidation (Psi), (e) une ou plusieurs voies de polypurine (PPT) et (f) un U3. La SOI se présente de préférence sous la forme d'un ADN simple brin ou d'un hybride ADN-ARN après initiation de la transcription inverse. L'invention concerne en outre des polynucléotides, des vecteurs, des cellules, des constituants, des compositions, des kits, des méthodes et des utilisations de la particule virale.
Patent WO-2021067944-A1 (WO)
Title: Procédés et systèmes pour des communications mobiles
Inventor: CALLAHAN DEANNA
IPC: G16H80/00
Filed: 2020-10-05
Abstract: Un procédé selon l'invention peut consister à déterminer, sur la base d'une date, un identifiant patient pour un patient planifié pour un rendez-vous, à déterminer, sur la base de l'identifiant patient, un numéro de dispositif mobile associé au patient, à envoyer, sur la base du numéro de dispositif mobile, un message interactif et à recevoir, en réponse au message interactif, une indication que le rendez-vous doit être maintenu ou annulé.
Patent WO-2021076746-A1 (WO)
Inventor: HUDSON ERIC A
IPC: H01L21/311
Filed: 2020-10-15
Abstract: L'invention concerne des procédés et des appareils pour graver sélectivement un matériau contenant du silicium et de l'oxygène par rapport à un matériau contenant du silicium et de l'azote par formation sélective d'une monocouche auto-assemblée contenant du carbone sur un matériau contenant du silicium et de l'azote par rapport à un matériau contenant du silicium et de l'oxygène. Des procédés sont également applicables pour graver sélectivement un matériau contenant du silicium et de l'azote par rapport au matériau contenant du silicium et de l'oxygène.
Patent WO-2021081232-A1 (WO)
Inventor: SURI ANISH
IPC: A61P35/00
Filed: 2020-10-22
Abstract: La présente invention concerne des lymphocytes T cytotoxiques (CTL) modifiés in vitro qui comprennent : a) un récepteur de lymphocytes T (TCR) spécifique d'un antigène présélectionné chez un être humain ; et b) un acide nucléique (s) codant pour un récepteur d'antigène chimère (CAR) spécifique d'un antigène associé au cancer. La présente invention concerne des procédés de production des CTL modifiés. La présente invention concerne des procédés de traitement du cancer, comprenant l'administration des CTL modifiés à un individu en ayant besoin.
Patent WO-2021086883-A1 (WO)
Inventor: FAKOORIAN SEYED ALI AKBAR
IPC: H04W72/04
Filed: 2020-10-28
Abstract: Methods, systems, and devices for wireless communications are described. Generally, the described techniques provide for efficiently selecting resources for sidelink communications in a shared spectrum while allowing other user equipment (UEs) a chance to gain access to the shared spectrum. In one aspect, a UE may transmit sidelink data to another UE in accordance with a frequency hopping pattern to randomize interference and improve throughput. According to some aspects, the first UE may transmit the sidelink data on a first set of interleaved frequency resources in a first time interval and a second, different set of interleaved frequency resources in a second time interval. In another aspect, a UE may rely on feedback from other UEs to determine when reserved resources are released, and the UE may use the released resources for sidelink communications.
Patent WO-2021087394-A1 (WO)
Title: Type i-b crispr-associated transposase systems
Inventor: SAITO MAKOTO
IPC: C12N15/10
Filed: 2020-10-30
Abstract: Systems and methods for targeted gene modification, targeted insertion, perturbation of gene transcripts, and nucleic acid editing. Novel nucleic acid targeting systems comprise components of CRISPR systems and transposable elements.
Patent WO-2021113135-A1 (WO)
Inventor: KIMURA AKITERU
IPC: G01C3/08
Filed: 2020-11-25
Abstract: An example method includes causing a distance sensor to project a pattern of light onto an object, causing the distance sensor to acquire an image of the pattern of light on the object, detecting an image position of a first point of light of the pattern on an imaging sensor, calculating a first estimated distance and a second estimated distance between the distance sensor and the object, based on the image position, causing the distance sensor to emit a pulse of light toward the object, causing the distance sensor to acquire an image of a reflected portion of the pulse of light, calculating a third estimated distance between the distance sensor and the object, based on a time of flight of the pulse, and calculating a fourth estimated distance between the distance sensor and the object, based on the first estimated distance, second estimated distance, and third estimated distance.
Patent WO-2021119437-A1 (WO)
Title: Procédés de synthèse de disiloxanes asymétriques
Inventor: ZHOU XIAOYUAN
IPC: C07F7/08
Filed: 2020-12-11
Abstract: La présente invention concerne des procédés de fabrication de disiloxanes d'alcényle, comprenant l'association d'un halosilane d'alcényle avec un halosilane d'alkyle et l'ajout du mélange à de l'eau, une solution aqueuse acide, ou une solution aqueuse basique. Le rapport entre l'halosilane d'alcényle et l'halosilane d'alkyle est compris dans une plage d'environ 10:1 à environ 1:1. L'halosilane d'alcényle et l'halosilane d'alkyle sont mélangés à une température d'environ 20 °C à environ 45 °C. Le produit de la réaction est séparé et lavé avec une solution de carbonate d'alcali saturée.
Patent WO-2021127007-A1 (WO)
Title: Anti-bcma car antibodies, conjugates, and methods of use
Inventor: FRIEDMAN KEVIN
IPC: A61K39/395
Filed: 2020-12-16
Abstract: The invention provides improved methods for detecting anti-BCMA CAR expression on T cells. The invention generally provides antibodies and antigen binding fragments thereof, conjugates thereof, and methods of using the same to detect, determine, or measure CAR T cells and/or CAR expression on one or more T cells.
Patent WO-2021097483-A1 (WO)
Inventor: ARORA PAYAL
IPC: A61Q11/00
Filed: 2020-11-12
Abstract: L'invention concerne des compositions de soins buccodentaires comprenant de la vitamine D, ou un dérivé de celle-ci ; un acide alcanoïque de formule R-COOH ou un sel de métal alcalin de celui-ci, où R est un groupe hydrocarbyle en C 1  à C 13  ; et un véhicule acceptable par voie orale. L'invention concerne également des procédés de fabrication et d'utilisation de celles-ci.
Patent WO-2022132190-A1 (WO)
Title: Ensemble écouvillon de prélèvement d'échantillon
Inventor: YEOM SEAN
IPC: A61B90/00
Filed: 2021-12-15
Abstract: Écouvillon (12) comprenant un bâtonnet (16) ayant une section poignée (18) et une section pointe (20). La section pointe (20) comprend une pluralité de lobes (22a, 22b, 22c) disposés axialement le long d'un axe longitudinal du bâtonnet (16). Plus particulièrement, les lobes (22a, 22b, 22c) comprennent un premier lobe (22a) situé à une extrémité distale du bâtonnet (16) et au moins un second lobe (22b, 22c) décalé axialement par rapport au premier lobe (22a). Le diamètre du premier lobe (22a) est inférieur au diamètre du second lobe (22b, 22c). Des fibres (F) sont fixées à la section pointe (20) pour prélever un échantillon à partir d'une cavité anatomique d'un patient. Une plaque d'arrêt (14) peut également être prévue pour une fixation amovible au bâtonnet (16) afin d'ajuster l'étendue selon laquelle la section pointe (20) peut être insérée dans la cavité.
Patent WO-2021173965-A1 (WO)
Inventor: RICKE DARRELL
IPC: A61K39/12
Filed: 2021-02-26
Abstract: Provided herein are universal prophylactic compositions for preventing infection with influenza viruses by directing the immune response to highly conserved regions of the virus. Also provided are universal therapeutic compositions for treating influenza infection by targeting the highly conserved regions. Methods for using the prophylactic and therapeutic compositions are also provided.
Patent WO-2021174091-A1 (WO)
Title: Conjugaison à médiation par la transglutaminase
Inventor: PONS JAUME
IPC: A61K39/395
Filed: 2021-02-26
Abstract: La présente divulgation concerne des conjugués anticorps-oligonucléotides ainsi que des procédés de préparation et d'utilisation associés. L'invention concerne également des composés, des compositions et des kits apparentés.
Patent WO-2021202056-A1 (WO)
Title: Système et procédé pour vaporisateur doseur
Inventor: Woodbine John Jesse
IPC: A61M15/06
Filed: 2021-03-06
Abstract: L'invention concerne un système et un procédé pour vaporisateur doseur (100). Plus précisément, un mode de réalisation du système comprend un boîtier (102) ayant une première extrémité (104) opposée à une seconde extrémité (106). Un embout buccal (108) est disposé à proximité de la première extrémité (102), l'embout buccal (108) étant structuré et agencé pour tourner autour de la première extrémité (102). Un moyen de fixation (112) est disposé à proximité de la seconde extrémité (106), le moyen de fixation (112) étant structuré et agencé pour une fixation amovible à une source d'alimentation. Un réservoir (114) de concentré liquide (116) est disposé à l'intérieur du boîtier (102). Un vaporisateur (118) est disposé à proximité du moyen de fixation (112) et isolé thermiquement du réservoir (114). Un conduit de vapeur (120) passe généralement du vaporisateur (118) à travers le boîtier (102) jusqu'à l'embout buccal (108). Un distributeur entraîné en rotation dosée (124), accouplé à l'embout buccal (108), applique une force prédéterminée sur le réservoir (114) pour distribuer à partir du réservoir (114), dans le vaporisateur (118), une quantité prédéterminée de concentré liquide (116).
Patent WO-2021188409-A1 (WO)
Title: Treatment of cytokine release syndrome with gm-csf antagonists
Inventor: PIRRELLO JOE
IPC: C07K16/28
Filed: 2021-03-15
Abstract: The present invention provides, among other things, a method of treating a subject with infection-induced hyperinflammation comprising administering to the subject a granulocyte-macrophage colony-stimulating factor (GM-CSF) antagonist at a therapeutically effective dose and an administration interval for a treatment period sufficient to improve, stabilize or reduce one or more symptoms of hyperinflammation. The present invention also provides, among other things, a method of inhibiting or reducing cytokine release syndrome (CRS) or acute respiratory distress syndrome (ARDS) in a subject comprising administering to the subject a granulocyte-macrophage colony- stimulating factor (GM-CSF) antagonist at a therapeutically effective dose and an administration interval for a treatment period sufficient to improve, stabilize or reduce one or more symptoms of CRS or ARDS.
Patent WO-2021252071-A1 (WO)
Title: Methods of monitoring a geometric property of a hydraulic fracture within a subsurface region, wells that perform the methods, and storage media that direct computing devices to perform the methods
Inventor: LIANG YUEMING
IPC: E21B47/00
Filed: 2021-04-13
Abstract: Methods of monitoring a geometric property of a hydraulic fracture within a subsurface region, wells that perform the methods, and storage media that direct computing devices to perform the methods provided. The methods include repeatedly measuring, at a plurality of measurement times, fiber strain as a function of position along a length of an optical fiber. The optical fiber is positioned within a wellbore that extends within a subsurface region and the repeatedly measuring is performed during a change in the geometric property of the hydraulic fracture. For a given measurement time of the plurality of measurement times, the methods also include differentiating the fiber strain as the function of position to generate a strain differential as a function of position along the length of the optical fiber. The methods further include determining the geometric property of the hydraulic fracture based, at least in part, on the strain differential.
Patent WO-2021216478-A1 (WO)
Inventor: ABRAHAMS CRISTINA
IPC: A61K47/60
Filed: 2021-04-20
Abstract: Interleukin-2 (IL-2) conjugates comprising at least one or more amino acid substitutions that bias binding to the IL-2 receptor βγ c  dimer over binding the IL-2 receptor αβγ c  trimer and a non-natural amino acid at or near the N-terminus conjugated to a water-soluble polymer are described. The IL-2 conjugates are useful for treatment and prevention of cell proliferation and cancer in a patient.
Patent WO-2021216969-A1 (WO)
Title: Contrôle d'activité multifactoriel
Inventor: BOWEN JAMES
IPC: C12Q1/00
Filed: 2021-04-23
Abstract: Les données provenant des capteurs d'activité sensibles aux enzymes indicatrices de divers états pathologiques sont combinées avec des données provenant d'autres sources, notamment les dossiers médicaux électroniques et les données cliniques, y compris les tests de diagnostic moléculaire. Les données regroupées peuvent être analysées pour identifier des profils indicatifs de certains événements, notamment le développement d'une maladie, la progression d'une maladie ou l'efficacité thérapeutique probable d'un traitement donné pour un patient.
Patent WO-2021225921-A1 (WO)
Title: Modified adeno-associated virus vectors that evade neutralizing antibodies and uses thereof
Inventor: LI CHENGWEN
IPC: C12N15/86
Filed: 2021-05-03
Abstract: The present invention is in the field of recombinant adeno-associated virus (AAV) vectors. In particular, the invention relates to AAV vectors comprising modified AAV capsid proteins that evade neutralizing antibodies but are still able to transduce hepatocytes. The invention further relates to methods of using the AAV vectors to deliver products to subjects and treat diseases.
Patent WO-2021262371-A1 (WO)
Title: Surface modification for metal-containing photoresist deposition
Inventor: YU JENGYI
IPC: G03F7/11
Filed: 2021-05-25
Abstract: Techniques described herein relate to methods, apparatus, and systems for promoting adhesion between a substrate and a metal-containing photoresist. For instance, the method may include receiving the substrate in a reaction chamber, the substrate having a first material exposed on its surface, the first material including a silicon-based material and/or a carbon-based material; generating a plasma from a plasma generation gas source that is substantially free of silicon, where the plasma includes chemical functional groups; exposing the substrate to the plasma to modify the surface of the substrate by forming bonds between the first material and chemical functional groups from the plasma; and depositing the metal-containing photoresist on the modified surface of the substrate, where the bonds between the first material and the chemical functional groups promote adhesion between the substrate and the metal-containing photoresist.
Patent WO-2022015480-A1 (WO)
Title: Directional guidance and layout compliance for item collection
Inventor: NG CHU PANG ALEX
IPC: G06Q30/00
Filed: 2021-06-24
Abstract: A method in a mobile computing device includes: obtaining order collection data containing (i) item identifiers corresponding to a set of target items and a set of non¬target items, (ii) a reference layout indicating, within a region of a facility, respective positions of the target items and the non-target items, and (iii) item recognition data for the target items and the non-target items; controlling an image sensor of the mobile computing device to acquire an image of a portion of the region; based on the item recognition data, detecting an item from the image; when the detected item is a target item, controlling an output assembly of the mobile computing device to present a prompt to collect the detected item; and when the detected item is a non-target item, controlling the output assembly to present a directional guide towards a selected target item based on the reference layout.
Patent WO-2022010708-A1 (WO)
Title: Intelligent repurposable cooling systems for mobile datacenter
Inventor: HEYDARI ALI
IPC: H05K7/14
Filed: 2021-06-30
Abstract: A cooling system for a datacenter is disclosed. An evaporative cooling subsystem provides blown air for cooling the datacenter and a repurposable refrigerant cooling subsystem controls moisture of the blown air in a first configuration and independently cools the datacenter in a second configuration.
Patent WO-2022026790-A1 (WO)
Inventor: CHOKSHI RITA
IPC: A61K8/92
Filed: 2021-07-30
Abstract: The instant disclosure relates to hair cosmetic compositions that include a cationic vinylpyrrolidone copolymer, an acrylate-based polymer, a cationic guar polymer, a cationic surfactant, including a cationizable surfactant, an amino functionalized silicone, a plant-based fatty compound, a fatty alcohol, an ester, and cosmetically acceptable solvent. Methods for using such hair cosmetic compositions are also provided.
Patent WO-2022026891-A1 (WO)
Inventor: BERTI LORENZO
IPC: C12Q1/682
Filed: 2021-07-30
Abstract: Methods and systems for detecting the presence of a target nucleic acid sequence in one or more samples of a plurality of samples are described. The methods may comprise the use of linear barcoded nucleic acid probes that, upon hybridization to a target nucleic acid sequence, may be ligated to circularize the probe molecule, amplified, and sequenced. The use of a probe-specific barcode integrated into the nucleic acid probe molecule, and sample-specific barcodes that may be incorporated into the nucleic acid probe molecule or added during the amplification step, enable large-scale multiplexed assay and sample processing.
Patent WO-2023014377-A1 (WO)
Inventor: PFEIFFER MATTHIAS T
IPC: G02F1/1335
Filed: 2021-08-06
Abstract: Des systèmes et des procédés pour des affichages transparents et réfléchissants lisibles par IR sont divulgués qui ne souffrent pas d'un aspect de type miroir ou d'une gradation indésirable de l'affichage dus à des empilements séquentiels de polariseurs. Les systèmes et procédés divulgués utilisent des DEL IR disponibles en plus de, ou à la place de, DEL de lumière visible. Un illuminateur ou un intégrateur, qui est un guide de lumière, est conçu pour maintenir l'état de polarisation de la lumière. L'affichage peut utiliser une lumière visible régulière, un polariseur avant et, par conséquent, ne subit pas de réduction de luminosité provoquée par un polariseur à capacité IR.
Patent WO-2022051688-A1 (WO)
Inventor: HSIAO YUNG-CHIN
IPC: G02B27/01
Filed: 2021-09-03
Abstract: The present disclosure describes systems and methods for improving binocular vision, which generate a virtual image moving between two different depths to stimulate and then strengthen the weaker/abnormal eye of the viewer to eventually improve or even restore his/her binocular vision based on the viewer's eye information. The system comprises an eye tracking module and a virtual image module. The eye tracking module is configured to provide eye information of the viewer. The virtual image module configured to display a first virtual object by projecting multiple normal light signals to a viewer's first eye to form a normal image and corresponding multiple adjusted light signals to a viewer's second eye to form an adjusted image.
Patent WO-2022056023-A1 (WO)
Inventor: WILLARD DEAN M
IPC: F24F11/49
Filed: 2021-09-08
Abstract: Systems and methods for operating an exits sign. The methods comprise: using the exit sign to denote a physical location of a closest exit of a building; obtaining, by the exit sign, sensor data generated by at least one sensor internal to or external from the exit sign, the sensor data specifying a condition or characteristic of equipment, an individual or a surrounding environment; and using the sensor data to facilitate at least one of (i) remote management of an emergency system for a building, (ii) locating of an individual or asset in the building, and (iii) management of an incident event by an organization.