baber/WOPTO huggingface dataset:
Patent CA-2914924-A1 (CA)
Inventor: ADANG ANTON EGBERT PETER
IPC: C07K16/28
Filed: 2014-06-13
Abstract: The invention provides a CD40 signalling inhibitor and a further compound for use in the treatment of chronic inflammatory disease in an individual in need thereof, wherein the further compound is a bile acid, a bile acid derivative, an TGR5-receptor agonist, an FXR-receptor agonist or a combination thereof. Also provided is a CD40 signalling inhibitor and a further compound for use in the prevention of cancer and/or fibrosis, wherein the further compound is a bile acid, a bile acid derivative, an TGR5-receptor agonist, an FXR-receptor agonist or a combination thereof.
Patent CA-2915154-A1 (CA)
Title: Use of opioid antagonists to attenuate endothelial cell proliferation and migration
Inventor: MOSS JONATHAN
IPC: A61K31/485
Filed: 2007-04-17
Abstract: The invention provides a use of a combination of a peripheral opioid antagonist of the Formula I such as methylnaltrexone and 5-fluorouracil (5-FU) for treating a disorder characterized by hyperproliferation of endothelial cells, hyperproliferation of cells overexpressing mu-opioid receptors, and for inhibiting proliferation of cancer cells. (see formula I)
Patent CA-2916095-A1 (CA)
Inventor: ZANK JOHANN
IPC: F42D1/08
Filed: 2014-06-20
Abstract: A mobile manufacturing and delivery platform that is adapted to provide in a blasthole an explosive composition comprising a liquid energetic material and sensitizing voids, the sensitizing voids being present in the liquid energetic material with a non- random distribution. The platform comprises a storage tank for the liquid energetic material; at least two delivery lines for conveying respective streams of the liquid energetic material from the storage tank; a void delivery system for producing sensitizing voids in at least one of the streams of liquid energetic material; a mixer for mixing the streams of liquid energetic material to produce the explosive composition; and a blasthole loading hose. The mixer may be provided at the end of the loading hose. A blasting method employs the platform to manufacture and deliver the explosive composition into a blasthole, which composition is subsequently detonated.
Patent CA-2917291-A1 (CA)
Title: Knit hemostatic bandage with glass fiber
Inventor: KENDALL RICHARD
IPC: A61L15/16
Filed: 2013-10-18
Abstract: A knit hemostatic bandage provided herein can include a continuous rayon fiber and a continuous glass fiber. The knit hemostatic bandage can have a gauge of between 10 and 30 stitches per inch. The knit hemostatic bandage can have a Young's modulus of elasticity of less than 50 MPa.
Patent CA-2917436-A1 (CA)
Title: Iron-based anode for obtaining aluminum by the electrolysis of melts
Inventor: SIMAKOV DMITRIY ALEXANDROVICH
IPC: C25C3/12
Filed: 2013-08-19
Abstract: ?The invention relates to nonferrous metallurgy, and specifically to an anode for electrolytically producing aluminum by the electrolysis of fluoride melts. An anode for producing aluminum by the electrolysis of melts at a temperature below 930ºC is comprised of a base, made of an alloy which contains, by mass percentage, iron (65-96), copper (up to 35), nickel (up to 20) and one or a plurality of additives of molybdenum, manganese, titanium, tantalum, tungsten, vanadium, zirconium, niobium, chromium, and aluminum (up to 1), and cobalt, cerium, yttrium, silicon and carbon (totaling up to 5), and a protective oxide layer comprised mainly of iron oxides and of complex oxides of iron, copper and nickel. The base is prepared by means of casting into metal molds or into sand molds. The protective oxide layer on the surface of the anode is produced by means of pre-oxidation in air at a temperature of 850-1050ºC, or directly, during the process of electrolysis, by oxidation using oxygen which forms on the anode. The protective oxide layer on the surface of the anode has a thickness of 0.1-3.0 mm.
Patent CA-2918387-A1 (CA)
Inventor: BEATTIE JODI LYNN
IPC: C12N15/82
Filed: 2014-07-18
Abstract: Disclosed herein are methods of controlling insect pests, in particular Leptinotarsa spp. which infest crop plants, and methods of providing plants resistant to such pests. Also disclosed are polynucleotides and recombinant DNA molecules and constructs useful in such methods, insecticidal compositions such as topical sprays containing insecticidal double-stranded RNAs, and solanaceous plants with improved resistance to infestation by Leptinotarsa spp. Further disclosed are methods of selecting target genes for RNAi-mediated silencing and control of Leptinotarsa spp.
Patent CA-2919222-A1 (CA)
Inventor: DUDKIEWICZ STEVEN M
IPC: H01P5/04
Filed: 2014-07-30
Abstract: A mechanical impedance tuner has at least two probe carriages mounted for movement along an axis parallel to the center conductor. The at least two probe carriages including a first probe carriage and a second probe carriage. Each probe carriage has at least N probes where N is an integer equal to or greater than one, and at least one of the N probes is mechanically different or of different nominal geometry from the probes on at least one of the other carriages so that each such probe has an non-identical frequency response.
Patent CA-2924619-A1 (CA)
Title: 4-azaindole derivatives
Inventor: PAYNE ANDREW
IPC: A61P25/00
Filed: 2014-09-30
Abstract: 4-Azaindole derivatives which are modulators of muscarinic acetylcholine receptor (mAChR) M1 and which may be effective for the prevention or disease modifying or symptomatic treatment of cognitive deficits associated with neurological disorders such as Alzheimer-type dementia (AD) or dementia with Lewy bodies (DLB), and a pharmaceutical composition comprising a 4-azaindole derivative as an active ingredient.
Patent CA-2927123-A1 (CA)
Title: Frozen confectionery product with an easy peelable gel coating and a method for manufacturing same
Inventor: MA CHANGPU
IPC: A23G9/48
Filed: 2014-11-28
Abstract: The invention relates to a frozen confectionery product comprising a core of a frozen confection, which is at least partially coated with a gel coating, characterized in that the gel coating is at least partly coated with a barrier coating of frozen liquid facilitating the peeling of the gel coating. The invention also relates to a method for making such a frozen confectionery product.
Patent CA-2927148-A1 (CA)
Title: Methods and compositions for treating cancer
Inventor: TORETSKY JEFFREY A
IPC: A61K31/40
Filed: 2014-10-20
Abstract: Methods and compositions provided herein relate to the treatment of cancer. In some embodiments, the compositions have utility in the treatment of cancers including glioblastoma multiforme and lung cancer.
Patent CA-2927431-A1 (CA)
Inventor: BHAMBHANI AKHILESH
IPC: C07K1/36
Filed: 2014-10-13
Abstract: Methods for preparing dried pellets of biological materials are described. The pellets can have a substantially spherical shape and are prepared by freezing droplets of a liquid composition of a desired biological material on a solid surface followed by microwave vacuum drying the frozen droplets. These methods are useful for preparing dried pellets having a high concentration of a desired biological material, in particular a therapeutic protein or vaccine, and which have a faster reconstitution time than lyophilized powder cakes prepared in vials.
Patent CA-2930322-A1 (CA)
Title: Detection et reconnaissance faciale
Inventor: MAN RO YONG
IPC: G06T3/60
Filed: 2014-11-12
Abstract: La présente invention, selon au moins un aspect, concerne des procédés et des systèmes qui détectent au moins un visage dans au moins une image numérique, déterminent et mémorisent des coordonnées de zone d'une position dudit visage détecté dans ladite image numérique, appliquent au moins une transformation audit visage détecté pour créer au moins un portrait dudit visage détecté, pivotent ledit portrait au moins jusqu'à ce que ledit portrait soit représenté suivant une orientation verticale et que les deux yeux dudit visage représenté dans ledit portrait se trouvent sur un plan horizontal ; et mémorisent ledit portrait pivoté.
Patent CA-2930416-A1 (CA)
Inventor: WYSOCKI PAUL F
IPC: G01D21/00
Filed: 2014-10-03
Abstract: A distributed sensing apparatus and system including one or more optical fibers disposed in a channel on the surface of a central member. A layer of film adhesive is disposed between the central member and a sheath. The film adhesive is circumferentially wrapped around the central member prior to arranging the sheath around the central member. The film adhesive is then cured and expanded to firmly attach the optical fiber to the sheath.
Patent CA-2932394-A1 (CA)
Inventor: PENNA CHRISTOPHER
IPC: A61B17/115
Filed: 2016-06-07
Abstract: An anvil assembly is provided. The anvil assembly includes center rod assembly, a head assembly pivotal relative to the center rod assembly between an operative position and a tilted position, and a mechanism for selectively maintaining the head assembly in the operative position.
Patent CA-2934456-A1 (CA)
Title: Fused heterocyclic compounds as ion channel modulators
Inventor: GRAUPE MICHAEL
IPC: C07D471/04
Filed: 2014-12-03
Abstract: The present disclosure relates to compounds that are sodium channel inhibitors and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes. In particular embodiments, the structure of the compounds is given by Formula I: wherein X, Y, Z, R2, R3, R4, p and q are as described herein, to methods for the preparation and use of the compounds and to pharmaceutical compositions containing the same.
Patent CA-2934697-A1 (CA)
Title: Process and apparatus for producing hydrocarbon
Inventor: IVERSEN STEEN BRUMMERSTEDT
IPC: C10G1/02
Filed: 2014-12-22
Abstract: The invention relates to a method for producing liquid hydrocarbon, the method comprising: providing a feed material, pressurizing the feed material to a predetermined process pressure, heating the pressurized feed material to a predetermined process temperature, reacting the pressurized and heated feed material for a predetermined period of time, cooling the reacted feed material and mechanically separating a high viscosity fraction from the converted feed material before conveying the remaining converted feed mass through a pressure reduction system and further through a separation system.
Patent CA-2937055-A1 (CA)
Inventor: HETZER TOBIAS
IPC: B65G47/31
Filed: 2015-02-03
Abstract: According to the invention a device and a method for portioning a flow of individual products is provided, said device and method having the following device features and method steps:  at least one input-side conveying device for continuously supplying individual products in one plane; at least two output-side conveying devices for continuously discharging the products in one respective plane, wherein the planes which are respectively assigned to the output-side conveying devices are arranged substantially vertically above one another; wherein the input-side conveying device transfers the products to a first of the at least two output-side conveying devices during a first time period, continuously or in batches; wherein the input-side conveying device and/or the output-side conveying devices are able to be adjusted, in particular pivoted, in their position, such that the input-side conveying device transfers the products to a further conveying device of the at least two output-side conveying devices during a second time period which follows the first time period, continuously or in batches; and wherein the input-side conveying device and the output-side conveying devices, in particular as circulating conveyor belts, in each case comprise conveying means, in particular in the form of front and/or rear ends which are movable in the direction of conveyance, which cooperate so that during the phase of adjusting the position of the input-side conveying device and/or the output-side conveying devices, the products on the input-side conveying device may be supplied continuously and substantially at uniform spacings from one another.
Patent CA-2938295-A1 (CA)
Title: Systeme et procede permettant d'appliquer une fermeture de capsule pour boissons gazeuses et sensibles a l'oxygene
Inventor: TORRISON MIRIAM
IPC: B65D53/04
Filed: 2015-01-28
Abstract: La présente invention concerne un système et un procédé permettant d'appliquer la fermeture de capsule pour une boisson gazeuse. Selon un mode de réalisation, un appareil comprend un joint de capsule présentant une forme de bague circulaire. L'appareil comprend, en outre, une lèvre externe et une partie interne de la forme de bague circulaire. La lèvre externe est plus grande que la partie interne, et la lèvre externe présente deux structures ou plus s'étendant en éloignement d'un centre de la lèvre externe.
Patent CA-2943261-A1 (CA)
Inventor: CONRAD RACHEL P
IPC: B65D33/16
Filed: 2016-09-27
Abstract: A re-closable, stand-up package with a tamper-evident opening system.  Production of the package originates from only two feed rolls. One roll is a flexible film web and the other is an adhesive tape. A reclosing layer is constructed from a strip of web material taken from a side of the feed roll and a length of the tape. The strip portion of the closure layer is perforated along tear lines which define a package opening. The tape and the strip are then adhesively joined so that they partially overlap vertically. The closure layer is then applied to the web over a slit in the front panel forming a re-closable primary opening. A gusset fold at the bottom of the package permits the package to be free-standing vertically upright.,Contents of the package can be dispensed only after rupture of the closure layer strip.
Patent CA-2944718-A1 (CA)
Title: Diffusion-optimized tipping paper
Inventor: LINDNER MICHAEL
IPC: A24C5/00
Filed: 2015-04-01
Abstract: The invention relates to a method for producing a diffusion-optimized tipping paper (4) for tobacco products, especially filter cigarettes, by plasma perforation of the web of tipping paper (4) for the purpose of maximum carbon monoxide reduction, wherein the diffusivity and the permeability P of the perforated tipping paper (4) are measured in-line and diffusivity is maximized by controlling the perforation parameters, the definable target permeability Psoll being maintained at all times.
Patent CA-2944959-A1 (CA)
Inventor: DONG XIAOWU
IPC: A61K31/497
Filed: 2015-03-21
Abstract: La présente invention concerne de nouveaux dérivés hétérocycliques contenant de l'azote substitué, représentés par la formule (I) et utilisables en tant qu'inhibiteurs de la kinase AKT, leurs isomères optiques, leurs sels pharmaceutiquement acceptables ou leurs solvates, formule (I) dans laquelle R1, R2, R3, R4, R5, R6, le cycle A, le cycle C, B, Q, Y, Z et m sont tels que définis de façon détaillée dans la description. De plus, l'invention concerne des médicaments contenant ces dérivés en tant que composants actifs, lesquels médicaments peuvent être utilisés pour le traitement de maladies prolifératives, telles que le cancer et l'inflammation et, en particulier, pour des maladies associées à la kinase AKT.
Patent CA-2947637-A1 (CA)
Inventor: TRAVERS PETER F
IPC: A61N2/02
Filed: 2015-07-10
Abstract: An insulated electrode system for delivering a plurality of tumor treating electromagnetic fields including an array of electrode elements for proximate location on a body of a patient. Each electrode element of the array having an insulation layer. Each electrode element being independently electrically accessible and configured to be dynamically assigned to emanate an electromagnetic field relative to at least one other of said electrode elements.
Patent CA-2947930-A1 (CA)
Inventor: REDMOND MICHELE EMILY
IPC: C09D7/63
Filed: 2014-05-16
Abstract: Antimicrobial micro- or nanoparticles comprising a chlorhexidine salt and an anion, and a method of making the antimicrobial micro-or nanoparticle, are disclosed. The anion in the salt is selected from oxoanions and partially hydrogenated oxoanions of phosphorus, carbon, nitrogen, and sulfur.
Patent CA-2951265-A1 (CA)
Inventor: NARAIN NIVEN RAJIN
IPC: C07H21/04
Filed: 2015-06-08
Abstract: The invention provides HSP90ß inhibitors comprising an antisense oligonucleotide targeting HSP90ß, pharmaceutical compositions comprising said inhibitors and methods of treatment of a metabolic syndrome by administering said HSP90ß inhibitors to a subject in need thereof. The antisense oligonucleotides may be targeted to skeletal muscle.
Patent CA-2952537-A1 (CA)
Inventor: HENSGEN LARS
IPC: B01J23/83
Filed: 2015-07-24
Abstract: A composition of formula (I) Ce1-a-b-cNaMbDcOx wherein M stands for one or more elements from the group of alkaline metals, except sodium, N is Bi and/or Sb, D is is present, or is not present, and if present is selected from one or more of Mg, Ca, Sr, Ba; Y, La, Pr, Nd, Sm, Gd, Er; Fe, Zr, Nb, Al; a is a number within the range of 0<a=0.9, b is a number within the range of 0<b=0.3, c is a number within the range of 0=c=0.2, a plus b plus c is <1, and x is a number within the range of 1.2=x=2, and its use for exhaust gas aftertreatment systems of Diesel engines, gasoline combustion engines, lean burn engines and power plants.
Patent CA-2953674-A1 (CA)
Inventor: CHON SANG-BAE
IPC: H04S5/02
Filed: 2015-06-26
Abstract: When a multichannel signal, such as a 22.2 channel signal, is rendered into a 5.1 channel signal, a three-dimensional acoustic signal can be reproduced using a two-dimensional output channel. However, when the elevation of an input channel differs from the standard elevation, the use of an elevation rendering parameter according to the standard elevation may cause the distortion of an acoustic image. The present invention solves the above-mentioned problem of the prior art. A method for rendering an acoustic signal according to an embodiment of the present invention for preventing the phenomenon of front-back confusion caused by a surround output channel comprises the steps of: receiving a multichannel signal including multiple input channels to be converted to multiple output channels; adding a predetermined delay to a frontal height input channel so that the output channels provide an acoustic image having a sense of elevation at a standard elevation angle; modifying the elevation rendering parameter for the frontal height input channel on the basis of the added delay; and on the basis of the modified elevation rendering parameter, generating an elevation-rendered surround output channel delayed with regard to the frontal height input channel, thereby preventing the front-back confusion.
Patent CA-2956671-A1 (CA)
Title: Mounting bracket for equipment rack
Inventor: JOST HENRY D
IPC: H05K7/18
Filed: 2017-01-30
Abstract: An equipment rack, a bracket for mounting on the equipment rack, and associated methods. The bracket includes a bracket body including a mounting section configured to mount equipment on the bracket. The bracket is configured to engage the frame assembly and form a releasable snap-fit connection with the frame assembly. The bracket can be configured to form mating connections with the frame assembly different than the snap-fit connection.
Patent CA-2959625-A1 (CA)
Title: Surface de spinelle de fer anti-cokefaction
Inventor: MAH EVAN GEEVOUY
IPC: C23C30/00
Filed: 2017-03-01
Abstract: Il est décrit pour lacier une surface anti-cokage ayant une épaisseur dun maximum de 15 microns et comprenant de 15,0 à 50,0 % massique de MnCr2O4; de 15,0 à 25,0 % massique de Cro.23Mn0.08Ni0.69; de 10,0 à 30,0 % massique de Crt3Fe0.7O3; de 12,0 à 20,0 % massique de Cr2O3; de 4,0 à 20,0 % massique de CuFe5O8; et moins de pourcentage massique dau moins un composé sélectionné parmi le groupe constitué du FeO(OH), du Cr+3O(OH), du CrMn, du Si et du SO2 (que ce soit sous forme doxyde de silicium ou de quartz) et moins de 0,5 % massique daluminium de toute forme, dans la mesure où la somme des composants est de 100,0 % massique.
Patent CA-2959683-A1 (CA)
Inventor: DUROJAIYE OLUMUYIWA M
IPC: G06F3/0354
Filed: 2015-09-11
Abstract: Techniques and architectures for detecting the handedness of a user from touch input and suppressing unintentional touch input are described. The techniques and architectures may analyze short-lived contacts that occur on a touch surface around a same time as input from an input tool to determine a hand that a user is using to hold the input tool. An inactive region may be established for the touch surface based on the hand determination and/or contextual information related to the user, the touch surface and so on. The inactive region may allow unintentional input to be identified and suppressed.
Patent CA-2960176-A1 (CA)
Inventor: FURTWANGLER TYLER R
IPC: G06F9/44
Filed: 2015-09-03
Abstract: The described technology is directed towards conditional wrapper that wraps part(s) of a selected program object with added logic, such as to perform validation and/or tracing on part(s) the object; the wrapper may be multi-functional in this regard. The wrapper logic is selectively added to one or more selected object parts by the object creator at object creation time based upon conditional data. During runtime, the added logic may be run before the wrapped part of the object (e.g., a function) is executed and/or after execution of the object part. Validation and/or tracing operations may be run before the part of the object is executed as well as after the part of the object is executed. Objects that do not meet the conditional data criteria are created and returned without any added wrapping logic.
Patent CA-2961554-A1 (CA)
Title: Managing a supply chain
Inventor: BIELEFELDT JAMES ALAN
IPC: G06Q10/08
Filed: 2014-10-22
Abstract: Logistics data includes a plurality of shipments, each including deliveries tied to a purchase order line item (POLI). Each of the deliveries has a delivery quantity and a post goods issue (PGI) date. The logistics data further includes a plurality of logistics services for the plurality of shipments including deliveries tied to the POLI. A multi-mode shipment has a plurality of sequential logistics services. The logistics data includes a plurality of deliveries tied to the POLI, wherein a goods received (GR) quantity and a GR date is determined for each of the deliveries. The processor provides a display of the PGI date and the GR date for the multi-mode shipment. The processor calculates the goods received (GR) date for a purchase order line item (POLI) based on multiple shipments tied to the POLI and multiple GRs tied to the POLI entered at a field location.
Patent CA-2963138-A1 (CA)
Inventor: DE GROOT ANNE
IPC: C12N15/12
Filed: 2008-01-29
Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
Patent CA-2963271-A1 (CA)
Inventor: CROSS JENNIFER L
IPC: A61K31/713
Filed: 2015-10-01
Abstract: The present invention provides compositions comprising therapeutic nucleic acids such as siRNA that target Hepatitis B virus (HBV) gene expression, lipid particles comprising one or more (e.g., a combination) of the therapeutic nucleic acids, and methods of delivering and/or administering the lipid particles (e.g., for treating HBV infection and/or HDV infection in humans).
Patent CA-2963968-A1 (CA)
Inventor: ARMANT D RANDALL
IPC: G01N33/68
Filed: 2015-10-12
Abstract: Methods of isolating and assaying fetal extravillous trophoblast cells, including assays of RNA of the fetal extravillous trophoblast cells according to aspects of the disclosure include obtaining a maternal endocervical sample containing fetal extravillous trophoblast cells from a pregnant subject; fixing the maternal endocervical sample in an aldehyde fixative, removing fetal extravillous trophoblast cells from the maternal endocervical sample thereby producing isolated extravillous trophoblast cells, isolating and assaying RNA from the fetal extravillous trophoblast cells.