baber/WOPTO huggingface dataset:
Patent NZ-601128-A (NZ)
Title: Certain triazolopyridines and triazolopyrazines, compositions thereof and methods of use therefor
Inventor: SU WEI-GUO
IPC: A61K31/429
Filed: 2010-12-30
Abstract: Disclosed are 1-(heteroarylalkyl)-6-(heteroaryl)-1H-[1,2,3]triazolo[4,5-b]pyrazine derivatives as represented by the general formual (1), and/or at least one pharmaceutically acceptable salt thereof, wherein: X is N; Y is absent; R1 is an optionally substituted fused bicyclic heteroaryl ring selected from pyrazolo[1,5-a]pyridine, imidazo[1,2-a]pyridine, imidazo[1,2-a]pyrazine, 1H-thieno[3,2-c]pyrazole, 1H-pyrrolo[2,3-b]pyridine, thieno[3,2-c]pyridine, imidazo[1,5a]pyridine, pyrido[3,2-d][1,3]thiazole, pyrazolo[3,4-b]pyridine, thieno[2,3-b]pyridine, [1,2,4]triazolo[1,5-a]pyridine, pyrazolo[1,5-a]pyrimidine, imidazo[1,2-b]pyridazine and 1H-pyrrolo[3,2-b]pyridine; R2 and R3 are independently selected from hydrogen, and alkyl, or R2 and R3, together with the carbon to which they are attached, form a ring chosen from 3- to 7-membered cycloalkyl and 3- to 7-membered heterocycle; R4 is selected from halo, alkyl, cycloalkyl, heterocycle, aryl and heteroaryl, each of which except for halo is optionally substituted; R5 is selected from hydrogen, halo, hydroxy, amino, trifluoromethyl, difluoromethyl, alkyl, alkenyl, and alkynyl; and wherein the remaining substituents are as defined herein. Representative compounds include those such as 1-(1-(imidazo[1,2-a]pyridin-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine. Further disclosed is a composition comprising at least one compound as defined above, and/or at least one pharmaceutically acceptable salt thereof and at least one pharmaceutically acceptable carrier for the treatment of cancer (and particularly for the treatment of lung cancer, stomach cancer, colorectal cancer, esophageal cancer, hepatocellular cancer, breast cancer, kidney cancer and ovarian cancer).
Patent NZ-606725-A (NZ)
Title: Methods for predicting anti-cancer response
Inventor: RICHARDSON ANDREA L
IPC: C12Q1/68
Filed: 2011-08-19
Abstract: The present invention is based, in part, on the identification of novel methods for defining predictive biomarkers of response to anti-cancer drugs.
Patent NZ-607118-A (NZ)
Title: C-met modulator pharmaceutical compositions
Inventor: WILSON JO ANN
IPC: C07D215/22
Filed: 2011-07-18
Abstract: Disclosed is a pharmaceutical composition as a tablet formulation, comprising by weight/weight percent: 25-29% of cabozantinib (N-[4-[(6,7-dimethoxy-quinolin-4-yl)oxy]phenyl]-N’-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide); microcrystalline cellulose; 40-44% anhydrous lactose; 2-4% hydroxypropyl cellulose; 2-8% croscarmellose sodium; 0.1-0.4% colloidal silicon dioxide; and 0.7-0.9% magnesium stearate. Cabozantinib may be in the form of the free base, or a pharmaceutically acceptable salt such as the malate salt, and which may be in crystalline or amorphous form. Also disclosed is a process for manufacturing a pharmaceutical composition as defined above, comprising the steps of: a. delumping unmilled cabozantinib; b. premixing the delumped cabozantinib with microcrystalline cellulose, anhydrous lactose and croscarmellose sodium to form a binder solution; c. wet high shear granulation of the binder solution to produce wet granules; d. wet screening of the wet granules to produce wet screened granules; e. fluid bed drying of the wet screened granules to produce dried granules; f. dry milling of the dried granules to produce dried milled granules; g. blending the dried milled granules with colloidal silicon and croscarmellose to produce an extragranular blend; h. lubricant blending of the extragranular blend and magnesium stearate to produce a final blend; i. tablet compression of the final blend to form an uncoated core tablet; and optionally j. film coating of the uncoated core tablet, such as with a film coating composition comprising iron oxide yellow containing hypromellose, titanium dioxide, and triacetin.
Patent NZ-617827-A (NZ)
Title: Active compound combinations comprising a (thio)carboxamide derivative and a fungicidal compound
Inventor: SEITZ THOMAS
IPC: A01P3/00
Filed: 2012-04-18
Abstract: Disclosed are fungicidal compositions, which comprises (A) a N-cyclopropyl-N-[substituted-benzyl]-3-(difluoromethyl)-5-fluoro-l-methyl-1H-pyrazole-4-carboxamide or thiocarboxamide derivative of formula (I) and a further fungicidally active compound (B). Also disclosed is a method for controlling the phytopathogenic fungi of plants or crops and the use of the composition for the treatment of seed. Examples of the compounds of formula (I) are: N-cyclopropyl-3-(difluoromethyl)-5-fluoro-N-(2-isopropylbenzyl)-1-methyl-1H-pyrazole-4-carboxamide N-cyclopropyl-3-(difluoromethyl)-5-fluoro-N-(2-isopropylbenzyl)-1-methyl-1H-pyrazole-4-carbothioamide N-[2-chloro-6-(trifluoromethyl)benzy 1]-N-cyclopropyl-3-(difluoromethyl)-5-fluoro-1-methyl-1H-pyrazole-4-carboxamide N-(2-tert-butyl-5-methylbenzyl)-N-cyclopropyl-3-(difluoromethyl)-5-fluoro-1-methyl-1H-pyrazole-4-carboxamide
Patent NZ-620978-A (NZ)
Title: Submarine construction for tsunami and flooding protection, for tidal energy and energy storage, and for fish farming
Inventor: HANS J SCHEEL
IPC: E02B3/06
Filed: 2014-02-07
Abstract: Disclosed is a tsunami barrier for resisting impulse waves. It has a wall with a lower end fixed on the ground underneath the water. The wall has double-fence structure with parallel fences. The space between the fences is filled with rocks or rubble or concrete blocks. The system has a double-pontoon bridge with two parallel pontoons separated by a gap broad enough to let rocks or rubble or concrete blocks be immersed through the gap. Each of the two parallel pontoons contains fence-expending means for temporarily holding the fences and immersing the fences into the sea.
Patent NZ-622460-A (NZ)
Title: Immunotherapy regimes dependent on apoe status
Inventor: BLACK RONALD
IPC: C07K16/18
Filed: 2008-10-17
Abstract: Disclosed is a humanized form of a mouse 3D6 (Bapineuzumab) antibody comprising three light chain and three heavy chain CDRs of the mouse 3D6 antibody and a human heavy chain in which positions 234, 235 and 237 are occupied by Ala, Ala and Ala respectively, wherein positions are numbered by the EU numbering system and 3D6 is a mouse antibody produced by hybridoma PTA-5130.
Patent NZ-624328-A (NZ)
Title: Process for preparing quinoline derivatives
Inventor: WILSON JO ANN
IPC: C07D413/12
Filed: 2012-10-22
Abstract: Disclosed herein is a process for preparing a compound of Formula I, comprising the steps: wherein: R1 is halo; R2 is halo; R3 is (C1-C6)alkyl or (C1-C6)alkyl optionally substituted with heterocycloalkyl; R4 is (C1-C)alkyl; and Q is CH or N; comprising: (a) contacting 1,1 -cyclopropane dicarboxylic acid with thionyl chloride in a polar aprotic solvent; (b) adding and a tertiary amine base to the mixture of step (a) to form a compound of Formula A; and (c) coupling a compound of Formula A with an amine of Formula B to form a compound of Formula I.
Patent NZ-627386-A (NZ)
Title: Portable dialysis machine with improved reservoir heating system
Inventor: FULKERSON BARRY NEIL
IPC: B01D61/28
Filed: 2013-12-20
Abstract: A dialysis machine having a double pan reservoir unit (1821) wherein said double pan reservoir unit comprises: an internal pan (1817) having an external surface and an internal surface and defining a first volume adapted to hold a fluid therein; an external pan (1810) having an external surface and an internal surface and defining a second volume adapted to house the internal pan with a space (1820) between the external surface of the internal pan and the internal surface of the external pan; a heating element, configured to generate heat and positioned within the space between the external surface of the internal pan and the internal surface of the external pan; and a first plurality of electrical contacts attached to the external surface of the external pan and electrically coupled to the heating element.
Patent NZ-628976-A (NZ)
Title: Sewage screening system
Inventor: DAVIS FREDERICK JAMES
IPC: E03F5/14
Filed: 2013-02-21
Abstract: Disclosed is a sewage screening system. The screening system comprises a tank (20) configured for attachment to a sewage channel. The tank (20) contains a sewage screen (30). The tank is arranged to receive sewage flow via an inlet (10) from an upstream point of the channel, direct the sewage flow through the sewage screen (30), and then return the screened sewage flow back into the channel via an outlet (80), at a downstream point, or directly to a downstream treatment. The tank (20) decreases the velocity of the sewage flow in the tank relative to the channel, such that grit can settle at the bottom of the tank. The velocity may be reduced by a diffuser section (12) adjacent the inlet (10). The sewage screen (30) comprises a working screening surface (31) positioned below the invert level of the sewage channel at the upstream point, when in use. A portion of the working surface (31) lies in a substantially horizontal plane. The screen may be in the form of an endless conveyor so the screenings may be transported away from the screening surface , up an inclined section (35), and offloaded at an outlet (36). The tank may comprise a storm water outlet (90) for overflow.
Patent NZ-630934-A (NZ)
Title: An improved cable dispensing apparatus
Inventor: SCOTT ALBERT ROBINSON
IPC: H02G1/06
Filed: 2013-03-05
Abstract: A cable dispensing apparatus mounted upon a vehicle (3) is disclosed. The apparatus is arranged to support a cable containing drum (12) with the reel facing to the side of the vehicle (3). An arm (16) is pivotally connected for movement between a stowed position and a cable dispensing position via an actuator (26). A cable guide (24) on the arm member guides the cable (24) from the drum (12) to a trench (42) disposed along a side of the vehicle.
Patent NZ-631264-A (NZ)
Title: Vent arrangement for a respiratory device
Inventor: FOOTE ROGER MERVYN LLOYD
IPC: A61M16/20
Filed: 2014-03-14
Abstract: An adjustable gas washout vent for a sleep apnoea mask is described. The vent (3400, 3456) has multiple directional configurations that can be adjusted by a control signal sent by a sensor that monitors for any obstruction, blocking or unwanted noise of the exhaust gas breathed out by the wearer. The vent allows for unobstructed flow from the mask if the wearer rolls over and blocks the open vent during sleep or if there is too much noise.
Patent NZ-711975-A (NZ)
Title: Drum mallet
Inventor: FRY TYLER
IPC: G10D13/02
Filed: 2014-03-13
Abstract: Existing drum mallets for use with a tenor drum or a bass drum are limited to create certain specific sounds but what is needed is a drum mallet that with the adaptation of readily selectable features or components can create other sounds, improve sound quality or swing characteristics. These features can include the shape of the stop member, influence of the position of a mallet head or the thickness of a peripheral outer wall, which can improve the swing characteristics of the drum mallet to create other sounds. The drum mallet of the present invention comprises an elongate main body having a top end and a bottom end, a handle portion extending from the bottom end towards the top end, and a mallet-head-receiving portion extending from the top end towards the bottom end; a mallet head mounted on the mallet-head- receiving portion of the elongate main body. A stop member is disposed at the bottom end of the handle portion of the elongate main body. The stop member has a top-facing abutment surface for receiving in abutting relation a portion of a flourish cord tied onto the elongate main body; wherein the top-facing abutment surface is distinctly angled with respect to the remainder of the outer surface of the stop member. A mallet head abutment member projects generally radially outwardly from said elongate main body. A mallet-head-receiving portion has a top end and a bottom end adjoined to said elongate main body, and has an enlarged portion with a top opening leading to a substantially hollow interior generally defined by a peripheral outer wall. The ratio of maximum thickness of the peripheral outer wall to the diameter of the enlarged portion is less than about 1 :5.
Patent NZ-713217-A (NZ)
Title: A noise barrier and a method of construction thereof
Inventor: HO WAI LUN
IPC: E04H17/26
Filed: 2014-04-11
Abstract: A noise barrier is described having noise barrier panels capable of being moved by the force of wind from a closed to an open position to allow passage of wind, so that the noise barrier has limited wind load. The noise barrier can be light weight because wind load on the noise barrier is limited. This provides that the noise barrier is easy to erect, possibly without requiring heavy machinery. The noise barrier panel is mounted on a mounting pole to be slide-able on the mounting pole, so that the noise barrier panel can be pushed from ground up.
Patent NZ-719895-A (NZ)
Title: Improved inference of nooutputofpriorpicsflag in video coding
Inventor: WANG YE-KUI
IPC: H04N19/70
Filed: 2014-12-30
Abstract: An apparatus for coding video information according to certain aspects includes a processor configured to determine a value of a flag associated with a current picture of a current layer to be decoded, the flag indicating whether pictures in a decoded picture buffer (DPB) should be output, wherein the current picture is an intra random access point (IRAP) picture that starts a new coded video sequence (CVS) and wherein the determination of the value of the flag is based on at least one of: (1) the chroma format of the current picture and the chroma format of the preceding picture, (2) the bit depth of the luma samples of the current picture and the bit depth of the luma samples of the preceding picture, or (3) the bit depth of the chroma samples of the current picture and the bit depth of the chroma samples of the preceding picture.
Patent NZ-720544-A (NZ)
Title: Post attachment
Inventor: O’TOOLE LAWRENCE
IPC: E04H17/14
Filed: 2016-05-26
Abstract: An attachment 100 that is suitable for being mounted to a Y- or T-shaped fence post 110 of the type that comprises a stalk and wings that project from the stalk 112. The attachment comprises a mounting portion 116 configured for mounting to the stalk 112 of the post 110, and not to the wings of the post 110, by at least one fastening element that extends through the stalk 112, the mounting portion 116 being configured such that it is restricted from rotating about the at least one fastener. The attachment 100 also comprises an elongate extension arm 118 extending from the mounting portion 116 so as to lie in or be parallel to a plane of the mounting portion 116, the elongate arm being integral wit the mounting portion. In this way, the attachment can assist in the transfer of forces from the elongate extension arm 118 into the stalk 112 of the post 110 where it can best be accommodated.
Patent NZ-720851-A (NZ)
Title: Fixation device for servicing wind turbine components
Inventor: TEICHERT PAUL
IPC: F03D1/00
Filed: 2014-12-10
Abstract: This disclosure relates to a fixation device for use on a wind turbine (1) comprising at least a wind turbine tower (2), a nacelle (3) and a hub (5) for a number of rotor blades (4). The fixation device provides at least one fixation location at the wind turbine (1) and comprises fixation arms (12, 13) configured for being arranged in connection with a bottom or side part of the nacelle. Each fixation arm (12, 13) has an attachment arrangement for a lifting and lowering line and is extendable from an inactive state in which the arm (12, 13) does not extend forward of the nacelle (3) to a position forward of the nacelle (3) at a level substantially at or below the rotation axis of the rotor blades (4). The fixation arms (12, 13) can be extended to a position forward of the nacelle (3) when the fixation device is required for maintenance work. It also allows the fixation device to avoid interference with the rotor blades (4) of the wind turbine (1) when it is stowed and not in use. The disclosure also extends to a wind turbine (1) comprising such a fixation device and a method of providing a fixation location in connection with a wind turbine (1).
Patent NZ-731433-A (NZ)
Title: Planing ship and method for manufacturing same
Inventor: IZUME MASAYUKI
IPC: B63B9/04
Filed: 2015-11-12
Abstract: Provided is a planing ship such that a rocking prevention device is prevented from interfering with the ship’s navigation, and the work for preventing the interference with the navigation can be simplified. A top plate 13 is installed between upper portions of a pair of longitudinal plates 8, and a water tank 12 is formed by a ship bottom plate 5, a stern plate 7, front portions of ship side plates 6, the pair of longitudinal plates 8, and the top plate 13. A through hole 14 is provided in the stern plate 7. At the bow-side end of the top plate 13, there is installed a communication pipe 15 for providing communication between the inside of the water tank 12 and the outside of the water tank 12.
Patent NZ-731571-A (NZ)
Title: T cell receptors
Inventor: VOLKOV ARSEN
IPC: C07K14/725
Filed: 2015-10-08
Abstract: The present invention relates to T cell receptors (TCRs) which bind the HLA-A*02 restricted peptide GLYDGMEHL (SEQ SD NO: 1) derived from the MAGE-A10 protein. The TCRs of the invention demonstrate excellent specificity profiles for this MAGE epitope. Also provided are nucleic acids encoding the TCRs; cells engineered to present the TCRs, cells harbouring expression vectors encoding the TCRs and pharmaceutical compositions comprising the TCRs, nucleic acids or cells of the invention.
Patent NZ-739511-A (NZ)
Title: Pyrazole pyrimidine derivative and uses thereof
Inventor: BEN NERIAH YINON
IPC: C07D405/14
Filed: 2016-08-04
Abstract: The present invention provides pyrazole pyrimidine derivatives of formula (I) which inhibit Casein kinase I (CKI) and/or lnterleukin-1 receptor-associated kinase 1 (IRAKI) and methods of their manufacture, compositions comprising them and uses thereof in methods of treating malignant disease and disorders and methods for treating inflammatory diseases and disorders.
Patent NZ-750707-A (NZ)
Title: Cot modulators and methods of use thereof
Inventor: BACON ELIZABETH
IPC: C07D401/14
Filed: 2016-06-30
Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) of Formala I. It also relates to methods of use and manufacture thereof in relation to cancer, diabetes, IBD and inflammatory disorder medicaments.
Patent NZ-751284-A (NZ)
Title: Novel jak1 selective inhibitors and uses thereof
Inventor: LIANG CONGXIN
IPC: C07D491/147
Filed: 2017-09-30
Abstract: The new 1H-furo[3,2-b]imidazo[4,5-d]pyridine derivatives are selective Jak1 kinase inhibitors useful in treating disorders related to Jak1 activities such as autoimmune diseases or disorders, inflammatory diseases or disorders, and cancer or neoplastic diseases or disorders.
Patent NZ-774989-A (NZ)
Title: Delivery of respiratory therapy
Inventor: GILLIVER DAVID MARK
IPC: A61M16/08
Filed: 2007-07-27
Abstract: A patient interface including an interfacing structure configured deliver the supply of air to at least the patient’s nose and two inlet conduits detachably connectable to the interfacing structure and adapted to deliver the supply of air to the interfacing structure. Each inlet conduit is configured to, in use, extend from the crown of the patient’s head or from in front of the crown of the patient’s head, along a respective side of the patient’s face between the patient’s eye and ear, and to the interfacing structure, each inlet conduit having a bottom portion configured to engage the interfacing structure in use, and a top portion in fluid communication with a supply of pressurized air in use. Each inlet conduit has at least one portion that is structured to allow movement between (1) an open phase (e.g. Fig. 3-1) in which the inlet conduit is configured to allow the flow of air sufficient to provide treatment of sleep disordered breathing and (2) at least a partially collapsed phase (e.g. Fig. 3-2a) in which the inlet conduit is at least partially collapsed to substantially impede or prevent the flow of air. Each inlet conduit is structured and configured to maintain the open phase without being pressurized by the supply of air.
Patent NZ-791507-A (NZ)
Title: Method and device for decomposing, recombining and playing audio data
Inventor: MORSY KARIEM
IPC: G06F3/16
Filed: 2020-03-17
Abstract: Besides the creative aspects of disc jockey (DJ) work, it is a major task of a DJ to seamlessly blend between two songs. For this purpose, conventional DJ equipment provides features for changing tempo and key of a song such as to match tempo and key of the other song, respectively, and provides controls for cross-fading volumes or parameters of audio effects, for example equalizer effects, of the two songs. In order to achieve a smooth transition, it is an aim of the DJ to avoid clashing of the vocals of the two songs. Embodiments of the present disclosure may address this by providing a method for processing and playing audio data, comprising the steps of: receiving mixed input data, the mixed input data being a sum signal obtained from mixing at least one first source track with at least one second source track, wherein the mixed input data are first mixed input data based on a periodic beat structure; decomposing the mixed input data to obtain at least a first decomposed track resembling the at least one first source track; generating output data based on the first decomposed track; playing the output data through an audio output; receiving second mixed input data different from the first mixed input data and having a periodic beat structure; performing at least one of a tempo matching processing or a key matching processing, wherein the tempo matching processing comprises: receiving first input data obtained from the first mixed input data and second input data obtained from the second mixed input data; time stretching or resampling of at least one of the first input data and the second input data; and outputting first output data and second output data which have mutually matching tempos; and wherein the key matching processing comprises: receiving the first input data obtained from the first mixed input data and the second input data obtained from the second mixed input data; pitch shifting of at least one of the first input data or the second input data; and outputting the first output data and the second output data which have mutually matching keys.
Patent PT-100386-A (PT)
Inventor: LARSON ERIC ROBERT
IPC: C07D239/48
Filed: 1992-04-15
Abstract: 2,4-Diaminopyrimidine derivatives as potentiators of chemotherapeutic agents in the treatment of cancer.
Patent PT-103728-A (PT)
Title: Embarcação para actividades em zonas ambientalmente sensíveis com sistema híbrido de propulsão eléctrica baseado em pilha de combustível a hidrogénio e energia fotovoltaica.
Inventor: FARIAS TIAGO ALEXANDRE ABRANCHES TEIXEIRA LOPES
IPC: B63H21/20
Filed: 2007-05-04
Abstract: O PRESENTE INVENTO DIZ RESPEITO A UMA EMBARCAÇÃO, CUJA CONFIGURAÇÃO É EM CATAMARAN, QUE FOI DESENVOLVIDA PARA ACTIVIDADES EM ZONAS AMBIENTALMENTE SENSÍVEIS. ESTÁ MUNIDA DE UM SISTEMA DE PROPULSÃO ELÉCTRICO HÍBRIDO POIS USA COMO FONTES ENERGÉTICAS A RADIAÇÃO DE ENERGIA SOLAR E O HIDROGÉNIO ARMAZENADO A BORDO. A ENERGIA SOLAR É RENOVÁVEL E O HIDROGÉNIO É OBTIDO A PARTIR DE FONTES RENOVÁVEIS, PELO QUE A EMBARCAÇÃO REALIZA A SUA OPERAÇÃO UTILIZANDO APENAS ENERGIAS RENOVÁVEIS. O SISTEMA DE PROPULSÃO É CONSTITUÍDO PELO MOTOR ELÉCTRICO (1) ACOPLADO AO HÉLICE E RESPECTIVO SISTEMA DE CONTROLO (2), UMA PILHA DE COMBUSTÍVEL A HIDROGÉNIO (3) E UM RESERVATÓRIO PRESSURIZADO PARA ARMAZENAR O HIDROGÉNIO (4), PAINÉÍS FOTOVOLTAICOS (5), UM SISTEMA DE BATERIAS (6), UMA UNIDADE DE DISTRIBUIÇÃO QUE GERE OS FLUXOS ENERGÉTICOS ENTRE AS VÁRIAS COMPONENTES DO SISTEMA PROPULSOR (7), E UMA UNIDADE DE PRODUÇÃO DE HIDROGÉNIO AMOVÍVEL (8) PODENDO FUNCIONAR INTEGRADO NA EMBARCAÇÃO OU EM TERRA JUNTO AO CAIS DA EMBARCAÇÃO, E QUE UTILIZA A ENERGIA ELÉCTRICA OBTIDA POR UM GERADOR EÓLICO E POR PAÍNÉIS FOTOVOLTAICOS.