baber/WOPTO huggingface dataset:
Patent AT-E217857-T1 (AT)
Inventor: FUERSTNER ALOIS
IPC: B01J31/12
Filed: 1999-02-02
Granted: 2002-06-15
Abstract: The present invention relates to methods for preparing macrocyclic products having 9 or more ring atoms by ring-closing diyne metathesis of suitable diyne substrates. The diyne substrates can be converted into cycloalkynes or into cycloalkadiynes by cyclodimerization, depending on the particular reaction conditions. Any alkyne metathesis catalyst can be used as the catalyst, regardless of whether said catalysts are heterogeneously or homogeneously present in the reaction medium. The preferred catalysts or pre-catalysts are transition metal alkylidyne complexes, transition metal compounds which form alkylidyne complexes under the reaction conditions, and transition metal compounds with metal-metal triple bonds. The method can be carried out with numerous functional groups, solvents, and additives. Using known methods, the formed macrocyclic cycloalkynes or cycloalkadiynes can be converted into numerous secondary products, especially macrocyclic cycloalkenes with a uniform configuration of the double bond, and used, e.g., for the synthesis of epothilone or epothilone analogues.
Patent AT-E267223-T1 (AT)
Inventor: DUTTON RICHARD NEILL
IPC: B32B27/28
Filed: 1999-02-24
Granted: 2004-06-15
Abstract: A multi-layer film including: (a) a substrate layer of a thermoplastic polymer film having opposed first and second surfaces; and (b) a heat sealable layer associated with the first surface of the substrate and including (i) a first acrylic polymer and (ii) a second polymer which is a copolymer including residues derived from one or more olefinically unsaturated monomers and residues derived from one or more olefinically unsaturated monomers which include one or more functional groups. The first polymer (i) has a glass transition temperature in the range of from 40 to 120° C. and a weight average molecular weight in the range of from 20,000 to 60,000, the second polymer (ii) is a copolymer of a C1-C4 olefinically unsaturated hydrocarbon and an olefinically unsaturated carboxylic acid, and the heat-sealable layer includes from 5 to 60% by weight of the first acrylic polymer and from 40 to 95% by weight of the second polymer.
Patent AT-E238241-T1 (AT)
Inventor: GAO YUAN
IPC: C01D1/00
Filed: 1999-11-12
Granted: 2003-05-15
Abstract: The present invention includes substantially single-phase lithium metal oxide compounds having hexagonal layered crystal structures that are substantially free of localized cubic spinel-like structural phases. The lithium metal oxides of the invention have the formula Li<SUB>alpha</SUB>M<SUB>beta</SUB>A<SUB>gamma</SUB>O<SUB>2</SUB>, wherein M is one or more transition metals, A is one or more dopants having an average oxidation state N such that +2.5<=N<=+3.5, 0.90<=alpha<=1.10, and beta+gamma=1. The present invention also includes dilithiated forms of these compounds, lithium and lithium-ion secondary batteries using these compounds as positive electrode materials, and methods of preparing these compounds.
Patent AT-E384792-T1 (AT)
Inventor: CHEN YVONNE
IPC: G01N33/53
Filed: 1999-11-16
Granted: 2008-02-15
Abstract: Antibody variants of parent antibodies are disclosed which have one or more amino acids inserted in a hypervariable region of the parent antibody and a binding affinity for a target antigen which is at least about two fold stronger than the binding affinity of the parent antibody for the antigen.
Patent AT-E345782-T1 (AT)
Inventor: MEZAACHE DJELILA
IPC: A61K9/00
Filed: 1999-10-26
Granted: 2006-12-15
Abstract: The invention relates to compositions useful for making taste-masked oral dosage forms which can be easily processed and which disintegrate rapidly when placed in the mouth. The compositions include coated liquiflash particles and shearform floss particles. Tablets are preferred dosage forms.
Patent DE-03818807-T1 (DE)
Title: Schutzhaut für flugzeug
Inventor: ARAFAT HUSAM R
IPC: B64C3/28
Filed: 2003-08-27
Abstract: Eine
schützende
Außenhaut
für ein Flugzeug,
umfassend:  ein Führungskantenelement,
das eine Tragflächen-Oberfläche mit
einer Außenfläche und
einer gegenüberliegenden
Innenfläche
bildet;  wenigstens eine in die Innenfläche eingelassene Tasche, wobei
jede Tasche eine Dicke hat, die geringer als die Dicke des Führungskantenelements
ist, wobei jede Tasche so konfiguriert ist, dass sie sich in Reaktion
auf einen Aufprall von einem Objekt mit dem Führungskantenelement verformt.
Patent DE-12823424-T1 (DE)
Title: Kugelgewindetrieb und Montageverfahren dafür
Inventor: SHINDO MASASHI
IPC: F16H25/22
Filed: 2012-08-01
Abstract: Kugelrollspindel mit einer Gewindewelle und mehreren Muttern, die aneinander gekoppelt und an die Gewindewelle angebaut sind, wobei die mehreren Muttern gekühlt werden, indem ein Kühlmittel durch Durchgangsöffnungen strömen gelassen wird, welche jeweils in den mehreren Muttern in axialen Richtungen der mehreren Muttern ausgebildet sind, wobei die Kugelrollspindel umfasst: Senkbohrungen der Durchgangsöffnungen, welche jeweils auf gegenüberliegenden Endflächen von beiden von angrenzenden Muttern der mehreren Muttern ausgebildet sind; und ein ringförmiges Dichtelement, welches zwei O-Ringe aufweist und in die Senkbohrungen eingesetzt ist, wobei die zwei O-Ringe auf dem ringförmigen Dichtelement von der Außenseite befestigt sind, sodass die zwei O-Ringe jeweils innerhalb der Senkbohrungen der angrenzenden Muttern angeordnet sind; wobei eine erste Tiefe einer ersten Senkbohrung der Senkbohrungen größer als eine Gesamtlänge des Dichtelements ist, wobei die erste Senkbohrung in einer der angrenzenden Muttern ausgebildet ist, wobei eine zweite Tiefe einer zweiten Senkbohrung der Senkbohrungen kleiner als die Gesamtlänge des Dichtelements ist, wobei die zweite Senkbohrung in der anderen der angrenzenden Muttern ausgebildet ist, und wobei umfängliche Positionen der ersten Senkbohrung und der zweiten Senkbohrung der angrenzenden Muttern dahingehend angeordnet sind, aufeinander an Positionen zu weisen, wo eine erwünschte Vorbelastung ausgeübt wird.
Patent DE-310582-T1 (DE)
IPC: A61B17/22
Filed: 1988-09-26
Abstract: The invention relates to a surgical instrument for ligation of internal tissues, such as hemorrhoids, in a cavity of the body by means of an elastic cord. The instrument comprises an inner front-cylinder (1) with the elastic cord (2) strained around its front end and a displaceable outer discharge-cylinder (3) arranged on the front-cylinder (1). At displacement the elastic cord (2) is pushed beyond the front-cylinder (1) and ligates the stem of a tissue (12) inserted in the front-cylinder (1). One of the two cylinders (1;3) is connected to a profiled tube (4) and the other cylinder (3;1) is connected to one end of a rigid strip (5), which constitutes the actuating means (6) for the relative displacement of the cylinders. The strip is preferably formed into an actuating loop and the displacement is attained by pressing the actuating loop (6) towards the tube (4).
Patent ES-2296568-T1 (ES)
Inventor: SNAPE EVAN WILLIAM
IPC: A61K31/554
Filed: 1998-07-28
Abstract: Crystalline 11-(4-Ä2-(2-hydroxyethoxy)ethylÜ-1-piperazinyl)-dibenzoÄb,fÜÄ1,4Üthiazepine may be prepared by crystallising 11-(4-Ä2-(2-hydroxyethoxy)ethylÜ-1-piperazinyl)-dibenzoÄb,fÜÄ1,4Üthiazepine from a non-aromatic solvent such as ethyl acetate, isobutyl acetate, methyl iso-butylketone or methyl tert-butyl ether, preferably in the absence of water. The crystalline material produced may be converted into a pharmaceutically acceptable salt such as a fumarate. The crystalline 11-(4-Ä2-(2-hydroxyethoxy)ethylÜ-1-piperazinyl)-dibenzoÄb,fÜÄ1,4Üthiazepine may be used to treat psychoses.
Patent CY-1107563-T1 (CY)
Inventor: JANSEN ROB
IPC: A61M15/00
Filed: 2007-02-23
Abstract: A breath-actuated inhaler for delivery of a medicament by inhalation from a canister (2) which is compressible to deliver a dose of medicament. The inhaler comprises a housing (1) for holding a canister (2) and including a mouthpiece (5) for delivery of a dose of medicament from a canister (2) held in the housing; and an actuation mechanism (6) for compressing a canister (2) held in the housing (1) in response to inhalation at the mouthpiece (5). The housing includes two separable portions (19, 20). The first housing portion (19) mounts the actuation mechanism (6). The second housing portion (20) houses the mouthpiece (5) and a duct (24) shaped to direct an inhalation flow from the mouthpeice (5) to the first housing portion (19) for triggering the actuation mechanism (6). The duct (24) and the mouthpiece (5) are integrally formed and separable from the second housing portion (20).
Patent CY-1108416-T1 (CY)
Title: Ενωσεις για την αγωγη του αλγους
Inventor: RICHARDSON PETER
IPC: A61K31/7076
Filed: 2008-10-15
Abstract: Περιγράφεται η χρήση ενώσεων με τον ακόλουθο τύπο ως αναλγητικών, ιδιαίτερα αντιυπεραλγησιακών: όπου το R είναι αλκοξύλιο με C1-4 και το Χ είναι Η ή ΟΗ.
Patent CY-1108642-T1 (CY)
Inventor: WEINER DAVID M
IPC: A61K45/06
Filed: 2008-12-03
Abstract: Behavioral pharmacological data with the compound of formula (I), a novel and selective 5HT2A/2C receptor inverse agonist, demonstrate  in vivo  efficacy in models of psychosis and dyskinesias. This includes activity in reversing MK-801 induced locomotor behaviors, suggesting that this compound may be an efficacious antipsychotic, and activity in an MPTP primate model of dyskinesias, suggesting efficacy as an anti-dyskinesia agent. These data support the hypothesis that 5HT2A/2C receptor inverse agonism may confer antipsychotic and anti-dyskinetic efficacy in humans, and indicate a use of the compound of formula (I) and related agents as novel therapeutics for Parkinson's Disease, related human neurodegenerative diseases, and psychosis.
Patent CY-1108688-T1 (CY)
Title: Μυκητοκτονα μειγματα στη βαση ενωσεων αμιδιου
Inventor: SCHELBERGER KLAUS
IPC: A01N37/32
Filed: 2009-01-14
Abstract: Μυκητοκτόνα μείγματα για την καταπολέμηση επιζήμιων μυκήτων, τα οποία περιέχουν ενώσεις αμιδίου τύπου I
Patent CY-1116537-T1 (CY)
Title: Ν-φαινυλ-διοξο-υδροπυριμιδινες χρησιμες ως αναστολεις ιου ηπατιτιδας c (hcv)
Inventor: DONNER PAMELA L
IPC: C07D239/553
Filed: 2011-09-13
Abstract: Η εφεύρεση αυτή αφορά: (α) Ενώσεις και άλατα αυτών που μεταξύ άλλων, αναστέλλουν HCV, (β) ενδιάμεσα χρήσιμα για την παρασκευή τέτοιων ενώσεων και αλάτων, (γ) συνθέσεις που περιλαμβάνουν τέτοιες ενώσεις και άλατα, (δ) μεθόδους για παρασκευή τέτοιων ενδιαμέσων, ενώσεων, αλάτων και συνθέσεων, (ε) μεθόδους χρήσης τέτοιων ενώσεων, αλάτων και συνθέσεων και (ζ) κιτ που περιλαμβάνουν τέτοιες ενώσεις, άλατα και συνθέσεις. Οι ενώσεις αυτές είναι χρήσιμες στην θεραπεία ηπατίτιδας C και είναι της ακόλουθης γενικής σύνταξης: Τύπος (I)
Patent CY-1118034-T1 (CY)
Title: Συνθεσεις για αναπνευστικη απελευθερωση ενεργων παραγοντων και συσχετιζομενες μεθοδοι και συστηματα
Inventor: VEHRING REINHARD
IPC: A61K9/00
Filed: 2016-09-21
Abstract: Συνθέσεις, μέθοδοι και συστήματα παρέχονται για πνευμονική ή ρινική απελευθέρωση ενεργών παραγόντων μέσω ενός εισπνευστήρα μετρούμενων δόσεων. Σε μια ενσωμάτωση, οι συνθέσεις συμπεριλαμβάνουν ένα μέσο εναιώρησης, σωματίδια ενεργού παράγοντα, και σωματίδια εναιώρησης, στα οποία τα σωματίδια ενεργού παράγοντα και τα σωματίδια εναιώρησης σχηματίζουν ένα συν-εναιώρημα στα πλαίσια του μέσου εναιώρησης.
Patent CY-1119829-T1 (CY)
Title: Βιοαποικοδομησιμες συνθεσεις απελευθερωσης φαρμακου
Inventor: GAUDRIAULT GEORGES
IPC: A61K47/34
Filed: 2017-11-22
Abstract: Περιγράφονται βιοαποικοδομήσιμες συνθέσεις απελευθέρωσης φαρμάκου που περιλαμβάνουν ένα συμπολυμερές τριών συστάδων που περιέχει έναν πολυεστέρα και μια πολυαιθυλενογλυκόλη και ένα συμπολυμερές δύο συστάδων που περιέχει έναν πολυεστέρα και μια πολυαιθυλενογλυκόλη με τελική κάλυψη, καθώς και μια φαρμακευτικώς δραστική ουσία.
Patent CY-1120303-T1 (CY)
Title: Βελτιωμενοι tnf συνδετες
Inventor: BUYSE MARIE-ANGE
IPC: C07K16/24
Filed: 2017-12-19
Abstract: Η παρούσα εφεύρεση σχετίζεται με αλληλουχίες αμινοξέων, ενώσεις, και πεπτίδια που δεσμεύονται στον παράγοντα νέκρωσης όγκων α («TNF» ή «TNF-α»). Ειδικότερα, η παρούσα εφεύρεση σχετίζεται με βελτιωμένες μονές μεταβλητές επικράτειες ανοσοσφαιρίνης βαριάς αλυσίδας (επίσης αναφερόμενες στο κείμενο ως «ISV's» ή «ISVDs») που δεσμεύονται σε παράγοντα νέκρωσης όγκων α, καθώς και με πρωτεΐνες, πολυπεπτίδια και άλλα δομήματα, ενώσεις, μόρια ή χημικές οντότητες που περιλαμβάνουν τέτοιες ISVDs, όλα μαζί χαρακτηριζόμενα ως TNF συνδέτες. Άλλες πτυχές, υλοποιήσεις, χαρακτηριστικά, χρήσεις και πλεονεκτήματα της εφεύρεσης θα καταστούν προφανή στον ειδικευμένο με βάση την αποκάλυψη στο κείμενο.
Patent CY-1123815-T1 (CY)
Title: Υποκατεστημενες ινδαζολες, διαδικασια για την παρασκευη τους, φαρμακευτικα παρασκευασματα, τα οποια τις περιεχουν, καθως και η χρηση τους για την παρασκευη φαρμακευτικων μεσων
Inventor: BOTHE ULRICH
IPC: C07D401/12
Filed: 2020-06-05
Abstract: Η παρούσα αίτηση διπλώματος ευρεσιτεχνίας αναφέρεται σε νέες υποκατεστημένες ινδαζόλες, στη διαδικασία παρασκευής τους, στη χρήση τους αυτοτελώς ή σε συνδυασμούς για τη θεραπευτική αντιμετώπιση και/ή την πρόληψη νόσων, καθώς και στη χρήση τους για την παρασκευή φαρμακευτικών μέσων για τη θεραπευτική αντιμετώπιση και/ή την πρόληψη νόσων, ειδικότερα για τη θεραπευτική αντιμετώπιση και/ή την πρόληψη της ενδομητρίωσης, καθώς και του συγγενούς με την ενδομητρίωση άλγους και άλλων συγγενών με την ενδομητρίωση συμπτωμάτων, όπως είναι, η δυσμηνόρροια, η δυσπαρευνία, η δυσουρία και το σύνδρομο σπαστικού πυελικού εδάφους, η διαταραχή των λεμφωμάτων, η ρευματοειδής αρθρίτιδα, η σπονδυλοαρθρίτιδα (ειδικότερα η ψωριασική σπονδυλοαρθρίτιδα και η αγκυλοποιητική σπονδυλίτιδα), ο ερυθηματώδης λύκος, η σκλήρυνση κατά πλάκας, η ωοθυλακιοπάθεια, η χρόνια αποφρακτική πνευμονοπάθεια (CΟΡD), η ουρική αρθρίτιδα, η λιπώδης ηπατική νόσος, η νόσος που σχετίζεται με την αντίσταση στην ινσουλίνη, τα ογκοματώδη νοσήματα και η ψωρίαση.
Patent CY-1123036-T1 (CY)
Title: Στεγνωτηριο, ειδικοτερα για το στεγνωμα ενδυματων και βοηθητικου εξοπλισμου για καθαρους χωρους
Inventor: GÉRARD PATRICK
IPC: B01D46/10
Filed: 2020-06-05
Abstract: Η παρούσα εφεύρεση αναφέρεται σε ένα στεγνωτήριο (1), ειδικότερα για το στέγνωμα ενδυμάτων και βοηθητικού εξοπλισμού για καθαρούς χώρους.
Patent CY-1123263-T1 (CY)
Title: Πολυκυκλικες ενωσεις ως αναστολεις κινασης τυροσινης bruton
Inventor: ARORA NIDHI
IPC: C07D495/16
Filed: 2020-08-18
Abstract: Η παρούσα αποκάλυψη κατευθύνεται σε ενώσεις του Τύπου (Ι) ως αναστολείς κινάσης Bruton και παρασκευή αυτών, καθώς επίσης συνθέσεις που περιλαμβάνουν ενώσεις του Τύπου (Ι).
Patent CY-1126062-T1 (CY)
Title: Σταθερη φαρμακοτεχνικη μορφη anti-ifnar1
Inventor: DEPAZ ROBERTO
IPC: A61K39/00
Filed: 2023-06-20
Abstract: Η παρούσα εφεύρεση αναφέρεται σε μια σταθερή, χαμηλού ιξώδους φαρμακοτεχνική μορφή αντισώματος, όπου η φαρμακοτεχνική μορφή περιλαμβάνει υψηλή συγκέντρωση ενός αντισώματος αντι-INFARl. Σε ορισμένες υλοποιήσεις, η εφεύρεση αναφέρεται γενικά σε μια σταθερή φαρμακοτεχνική μορφή αντισώματος που περιλαμβάνει περίπου 100 mg/mL έως περίπου 200 mg/mL αντισώματος ή θραύσματος αυτού που δεσμεύει ειδικά την ανθρώπινη ιντερφερόνη άλφα 1 (INFAR1)· περίπου 20 mM έως περίπου 80 mM λυσίνης ή άλατος αυτής- περίπου 0.02% έως περίπου 0.06% επιφανειοδραστικού μέσου- μη φορτισμένο έκδοχο- και ρυθμιστικό διάλυμα φαρμακοτεχνικής μορφής. Σε ορισμένες υλοποιήσεις, η εφεύρεση αναφέρεται σε έναν περιέκτη, δοσολογική μορφή ή/και κιτ. Σε ορισμένες υλοποιήσεις, η εφεύρεση αναφέρεται σε μια μέθοδο παρασκευής και χρήσης της σταθερής φαρμακοτεχνικής μορφής αντισώματος.
Patent HR-P20120325-T1 (HR)
Title: Material mixture for producing casting moulds for machining metal
Inventor: GUENTER WEICKER
IPC: B22C1/18
Filed: 2012-04-12
Abstract: Material mixture comprises a refractory molding base material, a binder based on water glass and a particulate metal oxide selected from silicon dioxide, aluminum oxide, titanium oxide and zinc oxide. An independent claim is also included for a process for the production of casting molds using the above material mixture.
Patent SI-1615651-T1 (SI)
Title: A process for the preparation of ferutinine from ferula genus plants
Inventor: BOMBARDELLI EZIO
IPC: A61K8/37
Filed: 2004-03-23
Abstract: The invention relates to a process for cosmetic treatment, including the reduction of superficial and deep wrinkles, using ferutinine from Ferula spp extracts.
Patent SI-1755630-T1 (SI)
Title: Pharmaceutical compositions from beard lichen (usnea barbata) and st. john's wort (hypericum perforatum) and their use
Inventor: SCHEMPP CHRISTOPH
IPC: A61P17/00
Filed: 2005-04-07
Abstract: New pharmaceutical compositions (A) contain 0.01-20 (preferably 0.11-20, especially 0.5-5) wt. % beard lichen ( Usnea barbata) extract (I) and 0.01-80 (preferably 0.11-20, especially 0.5-5) wt. % St. John's wort ( Hypericum perforatum) extract (II). ACTIVITY : Antiseborrheic; Dermatological; Vulnerary; Antiinflammatory; Antibacterial; Fungicide; Antipsoriatic. MECHANISM OF ACTION : UV-induced collagenase activation inhibitor; UV-induced prostaglandin E 2 synthesis inhibitor. In tests in primary human fibroblast cultures, the active collagenase (MMP-1) content (initially ca. 3.0 ng/ml) was increased to ca. 8.0 ng/ml by UVA-1 irradiation (60 J/cm 2>) to ca. 8 ng/ml; and on subsequent incubation for 24 hours with Usnea barbata extract (0.1 v/v) or a combination of the Usnea barbata extract (0.1 v/v) and Hypericum perforatum extract (0.1 v/v) was reduced to ca. 5.2 ng/ml or ca. 0.8 ng/ml respectively.
Patent SI-1747997-T1 (SI)
Title: Apparatus and method for filling
IPC: A23L2/00
Filed: 2005-07-28
Abstract: The device for filling packaging (2) with filling e.g. hot beverages, comprises a filling unit to fill the packaging, an arrangement for closing the packaging, which has a clasp (4) for opening the packaging, and a pivoting unit for pivoting the packaging so that the packaging clasp is in contact with the filling. The pivoting unit has a holding fork (12), which is arranged in the pivoting position below the packaging. The closing arrangement is mounted for closing a clasp cap on the packaging and closes openings lying next to the packaging clasp through welding. The device for filling packaging (2) with filling e.g. hot beverages, comprises a filling unit to fill the packaging, an arrangement for closing the packaging, which has a clasp (4) for opening the packaging, and a pivoting unit for pivoting the packaging so that the packaging clasp is in contact with the filling. The pivoting unit has a holding fork (12), which is arranged in the pivoting position below the packaging. The closing arrangement is mounted for closing a clasp cap on the packaging and closes openings lying next to the packaging clasp through welding of foil materials of the packaging. The closing arrangement inserts the packaging clasp or a part of the clasp into the opening through welding. The filling unit is formed through a part of packaging fastener or formed through an opening lying next to the packaging clasp or at the predetermined position of the packaging fastener. An arrangement is intended as a conveyor surface by which the packaging is conveyed in the pivoted position and has a conveyor belt (21). The pivoting unit pivots the packaging at 30[deg] , 45[deg] , 60[deg] , 75[deg] , 90[deg] , 100[deg] , 120[deg] , 140[deg] , 150[deg] , 180[deg] , 270[deg] or 360[deg] . An independent claim is included for a procedure for filling packaging with filling.
Patent SI-2351555-T1 (SI)
Title: Abuse resistance opioid transdermal delivery device
Inventor: REIDENBERG BRUCE
IPC: B09B3/00
Filed: 2005-02-15
Abstract: The present invention provides abuse-resistant transdermal delivery devices containing an opioid agonist intended for analgesic purposes in pain patients.
Patent SI-1861585-T1 (SI)
Title: Heat accumulation segment
Inventor: KHANIN ALEXANDER
IPC: F01D25/00
Filed: 2006-03-21
Abstract: A heat accumulation segment for local separation of a flow duct inside a turbo engine, from a stator housing that radially surrounds the flow duct is provided. The heat accumulation segment includes two axially opposed joining contoured elements that are engageable with two components that are axially adjacent along the flow duct. A first one of the two joining contoured elements has a radially oriented recess with a frustoconical contoured surface against which a securing pin having a frustoconical external contour that acts radially under force action from a component that adjoins the first joining contoured element, and the first joining contoured element has a collar portion having a radially upper collar surface and a radially lower collar surface. The collar portion is connected within a counter-contoured receiving contoured element in the axially adjacent component by a joining force that acts between the securing pin and the frustoconical contoured surface.
Patent SI-2277042-T1 (SI)
Title: Apparatus and method for determination of isotopic composition of non-exchangeable hydrogen and deuterium atoms in ethanol samples
Inventor: SMAJLOVIC IVAN
IPC: G01N33/00
Filed: 2008-06-19
Abstract: The invention is related to the instrumental analytical chemistry, further more to the stable isotope determination in food products. The present invention is referred to the alcohol thermal dehydration chamber, apparatus for “online” determination of isotopic composition of non-exchangeable hydrogen stable isotopes in ethanol samples, which comprises of: A) Alcohol thermal dehydration chamber, B) Detection device, which contains pyrolysis reactor and the Continuous Flow Isotope Spectrometer, and it is connected to the alcohol thermal dehydration chamber over C) System of valves, connectors and capillary tubes which are used for transfer of analyzed sample as for the purging of the alcohol thermal dehydration chamber; procedure for “online” determination of isotopic composition of non-exchangeable hydrogen stable isotopes in ethanol samples and procedure for “offline” preparation of ethene (ethylene) gas by means of alcohol thermal dehydration chamber and for the purpose of authenticity and geographical origin determination of wines, strong spirits, beer, fruit juices, honey and other food product which contain alcohol and/or fermentable sugars.
Patent SI-2758433-T1 (SI)
Title: Protein-based therapy and diagnosis of tau-mediated pathology in alzheimer's disease
Inventor: NOVAK MICHAL
IPC: G01N33/00
Filed: 2012-09-14
Abstract: The invention provides unique therapeutic and diagnostic antibodies, as well as their fragments, portions, derivatives, and variants thereof, that bind regions of the tau protein that contribute to the initiation and propagation of pathological tau-tau interactions, as well as methods of making them. The invention also relates to methods of using those antibodies for diagnostics, prevention, and treatment of Alzheimer's disease and related tauopathies. The present invention also provides a method for a prophylactic and therapeutic treatment of Alzheimer's disease and other neurodegenerative tauopathies. This method entails the injection of antibodies and/or peptide vaccines that elicits an immune response directed to pathological tau proteins and tau deposits in the brains of patients. Suitable vaccines represent a tau peptide carrying one or more of the tau therapeutic epitopes provided herein.
Patent TR-200000069-T1 (TR)
Title: Gaz geçirgen sert kontakt lens
Inventor: MITOMO KIKUO
IPC: C08F220/22
Filed: 1999-04-30
Abstract: Bulus gaz geçirgen sert kontakt lenslerin üretimi için, çapraz bagli bir gaz geçirgen sert kontakt lens malzemesini sicak basinçla germek ve daha sonra presle gerilmis malzemeyi makine ile islemekten meydana gelen bir yöntem ve %5 ila 50'lik bir sikistirma orani ve 300 ila 1,500 g'lik bir sikistirma-bükülmede parçalanma direncine sahip olacak sekilde sicak presle gerilmis bir çapraz bagli gaz geçirgen sert kontakt lens malzemesinden olusmus sert kontakt lensler ile ilgilidir. Bu bulusun yöntemine göre optik lekeler ihtiva etmeyen, mükemmel seffaf, dahili gerilimi az, dahasi takili oldugu zaman sorun yaratmayan ve uzun ömürlülügü iyilestirilmis bir gaz geçirgen sert kontakt lens etkili bir sekilde üretilebilir.