baber/WOPTO huggingface dataset:
Patent NZ-243905-A (NZ)
Title: Process for preparing a high internal phase emulsion useful in preparing absorbent foam material
Inventor: DESMARAIS THOMAS ALLEN
IPC: C08F/
Filed: 1992-08-11
Abstract: Disclosed is a process for the continuous preparation of high internal phase emulsions which are suitable for subsequent polymerization into polymeric foam materials that, upon dewatering, act as absorbents for aqueous body fluids. The process involves continuous introduction of a certain type of monomer-containing oil phase and a certain type of electrolyte-containing water phase into a dynamic mixing zone at relatively low water to oil phase ratios. Flow rates are then steadily adjusted to increase the water to oil ratio of the streams fed to the dynamic mixing zone while subjecting the dynamic mixing zone contents to shear agitation which is sufficient to thereby form a high internal phase emulsion that, upon subsequent polymerization, provides a foam having an average cell size of from about 5 to 100 microns. The formation of such a stable high internal phase emulsion is completed by feeding the contents of the dynamic mixing zone to and through a static mixing zone.
Patent NZ-245214-A (NZ)
Title: Oral dosage forms comprising 3-pyridyl-1-hydroxy-ethylidene-1,1-bisphosphonic acid (risedronate) and having an enteric coating to delay release until the lower intestinal tract
Inventor: DANSEREAU R J
IPC: A61P3/14
Filed: 1992-11-23
Abstract: The present invention is directed to a novel enteric-coated oral dosage form of a risedronate active ingredient comprised of a safe and effective amount of a pharmaceutical composition which is comprised of a risedronate active ingredient and pharmaceutically-acceptable excipients. Said dosage forms prohibit the exposure of the risedronate active ingredient to the epithelial and mucosal tissues of the buccal cavity, pharynx, esophagus, and stomach and thereby protects said tissues from erosion, ulceration or other like irritation. Accordingly, the said dosage forms effect the delivery to the lower gastrointestinal tract of said human or other mammal of a safe and effective amount of the risedronate active ingredient, and substantially alleviate the esophagitis or esophageal irritation which occasionally accompanies the oral administration of risedronate active ingredients.
Patent NZ-270970-A (NZ)
Title: Pasta mixture extruded through die with the aid of a gear pump
Inventor: JUENGLING DANIELE
IPC: A21C11/20
Filed: 1995-04-21
Abstract: Pasta is mfd. by mixing cereal flour or semolina with 25-40% water. The mixt. is kneaded and extruded. The mixt. is forced through the extruder by a gear pump. Mixing and kneading of the pasta is pref. effected by two screws rotating in the same sense and meshing with each other. Cereal flour of particle size 50-150 mu m or cereal semolina of 250-350 mu m is used. The mixt. and kneading processes take 20-60 secs., during which time the pressure is maintained at 1-12 bar. Extrusion is carried out at 80-120 bar. Before extrusion the mixt. is degassed by applying a vacuum of 0.2 bar. The temp. is kept < 55 degrees C. at all times. <IMAGE>
Patent NZ-276495-A (NZ)
Title: Composition comprising menthol and carvone for inhibiting potato sprout and/or fungal growth, slow release composition comprising menthol and carvone, or carvone alone
Inventor: DIEPENHORST PEITER
IPC: A23B7/154
Filed: 1994-10-03
Abstract: PCT No. PCT/NL94/00240 Sec. 371 Date Sep. 20, 1996 Sec. 102(e) Date Sep. 20, 1996 PCT Filed Oct. 3, 1994 PCT Pub. No. WO95/09536 PCT Pub. Date Apr. 13, 1995A composition suitable for inhibiting potato sprouting and inhibiting the growth of fungi and decay bacteria, including a mixture of carvone and menthol, a method for inhibiting potato sprouting by using such composition and the use thereof, and a composition in the form of an emulsion or granulate which includes carvone and menthol or carvone alone, giving rise to a delayed release of the active compound and an extension of the length of sprout inhibition.
Patent NZ-282601-A (NZ)
Title: Producing fibrinogen in transgenic animals by germ line modification
Inventor: GARNER IAN
IPC: C07K14/75
Filed: 1995-03-01
Abstract: Materials and methods for producing fibrinogen in transgenic non-human mammals are disclosed. DNA segments encoding Aα, Bβ and γ chains of fibrinogen are introduced into the germ line of a non-human mammal, and the mammal or its female progeny produces milk containing fibrinogen expressed from the introduced DNA segments. Non-human mammalian embryos and transgenic non-human mammals carrying DNA segments encoding heterologous fibrinogen polypeptide chains are also disclosed.
Patent NZ-286509-A (NZ)
Title: Stabilised microemulsions of 3-isothiazolone derivatives (free of inorganic metal salts) using water, organic solvents, and anionic surfactants
Inventor: GIRONDA KEVIN FITZGERALD
IPC: A01N43/80
Filed: 1996-05-03
Abstract: Dilute solutions of 0.5 to about 5 % by weight of at least one 3-isothiazolone selected from the group consisting of 5-chloro-2-methyl-4-isothazolin-3-one and 2-methyl-4-isothazolin-3-one are stabilized without using inorganic metal salts or hydrogen peroxide by forming a microemulsion composition with organic solvent(s) having less than 6 percent by weight solubility in water; anionic surfactant(s); and optionally, non-ionic surfactant(s).
Patent NZ-333456-A (NZ)
Title: Type-2 chemokine binding proteins and methods of use therefor
Inventor: MCFADDEN GRANT
IPC: A61P31/04
Filed: 1997-05-21
Abstract: The specification describes the use of a therapeutically effective amount of a type-2 chemokine binding protein having 50% identity with the Shope fibroma virus  T1 protein, as set forth in GenBank Accession No: P25946  to manufacture pharmaceuticals to treat disease syndromes associated with acute or chronic dysregulated inflammatory responses.
Patent NZ-335094-A (NZ)
Title: Preparing nanoparticles formed of a statistic polymer
Inventor: BRU-MAGNIEZ NICOLE
IPC: A61K31/4168
Filed: 1999-04-23
Abstract: A method for preparing nanoparticles formed of a polymerised methylidene malonate compound of at least one compound of formula (I) in which A represents a group (a) or a group (b); R1 and R2 are identical or different represents a linear or branched C1-6alkyl group; n = 1, 2, 3, 4, or 5, characterised in that the monomer is previously made soluble in an organic aprotic solvent miscible in water forming with the polymerisation medium a mixture non-solvent of the formed polymer. The formed nanoparticles may contain optionally one or several biologically active molecules, and the pharmaceutical compositions containing them.
Patent NZ-500728-A (NZ)
Title: Composite material spring modules with integrally formed attachment fittings
Inventor: QUINTILE MARK J
IPC: A47C27/06
Filed: 1998-04-16
Abstract: Composite material spring modules (16) and methods of manufacture are described having a fiber reinforced composite material spring body (32) with attachment fittings (34, 36) integrally formed about the spring body (32). The attachment fittings (34, 36) are molded of a flexible material which dynamically responds to changes in the shape of the spring body (32) upon deflection. Integral formation of the fittings (34, 36) with the spring body (32) provides a unified single piece module which is readily attachable to any structure where spring support is desired. The composite material spring modules (16) are described as a mattress foundation (10), by attachment to high and low profile frames (12) and to an overlying grid (14). Methods of manufacture of the composite material spring modules (16) with integrally formed attachment fittings (34, 36) are described. Methods of assembly of flexible weight bearing structures such as mattress foundations (10) using the composite material spring modules (16) are also described.
Patent NZ-501998-A (NZ)
Title: Production of polyketides in plants
Inventor: BETLACH MARY C
IPC: C12N9/12
Filed: 1998-07-10
Abstract: Provided are genetically altered plants and plant cells that have been modified to contain expression system(s) capable of expressing a functional polyketide synthase (PKS), preferably 6-MSAS. The plants are selected from peas, peppers, petunias, corn, wheat, cotton and tobacco.
Patent NZ-503703-A (NZ)
Title: use of corticotropin release factor antagonist to treat sudden death by improving the QT dispersion and heart rate variability
Inventor: FOSSA ANTHONY ANDREA
IPC: A61K31/41
Filed: 2000-03-31
Abstract: A corticotropin releasing factor antagonist such as a compound of formula (I) or (II) or a pharmaceutically acceptable salt thereof is used in the manufacture of a medicament for preventing sudden death in an animal. In formula I and II: the dashed line represents an optional double bond; A is -CR7 or N; B is -NR1R2, -CR1R2R11, -C(=CR1R12)R2, -NHCR11R1R2, -OCR11R1R2, -SCR11 R1 R2, -CR11R2OR1, -CR11 R2SR1, -C(S)R2, -NHNR1R2, -CR2R11NHR1 or -C(O)R2; D is N or -CR10 when a double bond connects E and D and E is -CR4; -CR10 when a double bond connects E and D and E is N; or -CR8R9, -CHR10, -C=O, -C=S, -C=NH, or -C=NCH3 when a single bond connects E and D; E is -CR4 or N when a double bond connects E and D, and E is -CR4R6 or -NR6 when a single bond connects E and D; Y is N or -CH; Z is NH, O, S, -N(alkyl), or -CR12R13; R3 is hydrogen, alkyl, fluoro, chloro, bromo, iodo, hydroxy, amino, SH, -NH(alkyl), -N(alkyl)(alkyl), -CH2OH, -CH2OCH3, -O(alkyl), (alkyl)sulphanyl, (alkyl)sulphonyl, or (alkyl)sulphinyl, wherein alkyl moieties optionally contain one double or triple bond and are optionally substituted; R4 is hydrogen, alkyl, fluoro, chloro, bromo, iodo, alkoxy, formyl, trifluoromethoxy, -CH2OCH3, -CH2OCH2CH3, -CH2CH2OCH3, -CH2CF3, CF3, amino, nitro, -NH(alkyl), -N(CH3)2, -NHCOCH3, -NHCONHCH3, (alkyl)sulphanyl, (alky)sulphinyl, (alkyl)sulphonyl, cyano, hydroxy, -CO(alkyl), -CHO, or -CO2(alkyl), wherein alkyl moieties optionally contain one double or triple bond and are optionally substituted; R5 is optionally substituted phenyl, naphthyl, thienyl, benzothienyl, pyridyl, quinolyl, pyrazinolyl, pyrimidyl, imidazolyl, furanyl, benzofuranyl, benzothiazolyl, isothiazolyl, benzoisothiazolyl, thiazolyl, isoxazolyl, benzisoxazolyl, benzimidazolyl, triazolyl, pyrazolyl, pyrrolyl, indolyl, azaindolyl, benzoxazolyl, oxazolyl, pyrrolidinyl, thiazolidinyl, morpholinyl, pyridinyl, tetrazolyl, or a 3- to 8-membered cycloalkyl ring or a 9- to 12-membered bicycloalkyl ring system, wherein the cycloalkyl ring and said bicycloalkyl ring system optionally contain one or two of O, S, or -N-G wherein G is hydrogen, alkyl, alkanoyl, phenyl, or benzyl and R1, R2, R6, R7, R10 to R13 are as defined in the specification.
Patent NZ-505145-A (NZ)
Title: Retroviral packaging plasmid for production of recombinant retrovirus in humans
Inventor: FINER MITCHELL H
IPC: C12N7/04
Filed: 2000-06-14
Abstract: A method of transducing mammalian haematopoietic stem cells with retroviral supernatants produced by transient transfection is disclosed. The method involves a transient cotransfection of a first population of mammalian cells that can produce a virus with a retroviral helper DNA sequence and a retroviral vector encoding a foreign gene. This enables the population of mammalian cells to produce replication-defective recombinant retroviral vectors carrying the foreign gene that can found in the cell supernatant. A second population of mammalian cells is grown on culture plates with adhesion molecules or antibodies to adhesion molecules, and is incubated with the supernatant collected from the first population of mammalian cells. The cells transduced with the foreign gene are also claimed.
Patent NZ-506086-A (NZ)
Title: Tumor-associated antigen derivatives from the mage family, and nucleic acid sequences encoding them, used for the preparation of fusion proteins, antigens comprising derivatised thiol residues and of compositions for vaccination
Inventor: CABEZON SILVA TERESA
IPC: A61K39/00
Filed: 1999-02-02
Abstract: A tumour-associated antigen from the MAGE family wherein the antigen comprises derviatised thiol residues.
Patent NZ-507563-A (NZ)
Title: Gene encoding a protein having activity of transferring sugar onto aurone
Inventor: SAKAKIBARA KEIKO
IPC: C12P19/60
Filed: 2000-02-16
Abstract: A gene encoding a protein that has an amino acid sequence as shown in SEQ ID NO:2 and 8 to 10 and has an activity of transferring a glycosyl group to aurones is described. Also described are nucleic acids encoding the protein, vectors, non-human host cells transformed with the vectors, methods of producing a protein having activity of transferring a glycosyl group to aurones. A method of stabilizing aurones in a plant body is also described.
Patent NZ-508194-A (NZ)
Title: An enteric-coated pharmaceutical composition suitable for an acid labile high drug load medicament that is sensitive to a pH of less than 3
Inventor: ULLAH ISMAT
IPC: A61K9/50
Filed: 1998-08-04
Abstract: Provided is a high drug load enteric coated pharmaceutical composition that includes a core comprised of a medicament which is sensitive to a low pH environment of less than 3, such as ddl (also known as didanosine or 2',3'-dideoxyinosine, and marketed by Bristol-Myers Squibb Co. under the brand name Videx® and is an acid labile drug that has been shown to be effective in the treatment of patients with the HIV virus).  The composition is preferably in the form of beadlets having an enteric coating formed of methacrylic acid copolymer, plasticizer and an additional coat comprising an anti-adherent.  The so-called beadlets have excellent resistance to disintegration at pH less than 3 but have excellent drug release properties at pH greater than 4.5.  A method of making said pharmaceutical composition is also disclosed.
Patent NZ-508536-A (NZ)
Title: Dry powder dispersing apparatus and methods for their use
Inventor: BURR JOHN D
IPC: A61M15/00
Filed: 1999-05-19
Abstract: Disclosed  are  various  apparatus  and  methods   for aerosolizing   a  powdered  medicament.  In  one   exemplary embodiment,   an   apparatus   includes   a   pressurization cylinder,  and  a  piston  which  is  slidable  within   the cylinder  to  pressurize a gas. A handle is coupled  to  the piston  and  is movable between an extended position  and  a home   position  to  pressurize  the  gas.  An  aerosolizing mechanism  is  included and is configured  to  aerosolize  a powdered  medicament that is held within a  receptacle  with pressurized  gas from the cylinder. A carriage  assembly  is included  to  receive  the  receptacle  and  to  couple  the receptacle  to  the aerosolizing mechanism. A  first  and  a second  interlock are operably engageable with the  carriage assembly  to  prevent  coupling of the receptacle  with  the aerosolization  mechanism. The first interlock  is  released to  allow  movement  of the carriage upon  movement  of  the handle  to  the  extended  position.  The  second  interlock remains   engaged  if  the  receptacle  is  only   partially inserted into the carriage assembly.
Patent NZ-509324-A (NZ)
Title: Antiparasitic artemisinin derivatives (endoperoxides)
Inventor: HAYNES RICHARD KINGSTON
IPC: A61K31/5377
Filed: 1999-07-14
Abstract: C-10 substituted derivatives of artemisinin of formula (I) in the treatment of diseases caused by infection with a parasite wherein Y represents a halogen atom, an optionally substituted cycloalkyl, aryl, C-linked heteroaryl or heterocyclylalkyl group or a group -NR1R2; and a process for the preparation thereof.
Patent NZ-510148-A (NZ)
Title: Process for the inhibition of scale in kraft process and polymeric antiscalants for same
Inventor: DUGGIRALA PRASAD YOGENDRA
IPC: C08F216/04
Filed: 1999-06-21
Abstract: A process for inhibiting calcium carbonate scaling in aqueous systems such as that employed in the kraft process for the production of wood pulp is disclosed. Such a process is achieved by the addition to the system of at least one antiscalant comprising at least one monomer unit derived from the group consisting of 1,2-dihydroxy-3- butene, N-(hydroxymethyl) acrylamide, and N-(sulfomethyl) acrylamide, and at least one monomer unit derived from the group consisting of maleic acid, acrylic acid, acrylamide, methacrylic acid, itaconic acid, vinyl sulfonic acid, styrene sulfonic acid, N-tertbutylacrylamide, butoxymethylacrylamide, N,N-dimethylacrylamide, sodium acrylamidomethyl propane sulfonic acid, and salts thereof, with the proviso that said polymers do not contain the monomer unit -(CH2-CH=CH-CH2-O)-.
Patent NZ-511721-A (NZ)
Title: Use of 17-ketosteroid compounds and derivatives, metabolites and precursors thereof in the treatment of hepatitis C virus and other togaviruses
Inventor: PRENDERGAST PATRICK T
IPC: A61K31/56
Filed: 1999-11-24
Abstract: A 17-ketosteroid derivative of formula (I) or the salts, stereoisomers, positional isomers, metabolites, analogs, precursors, hydrates, tautomers, ionized forms and solvates thereof is used in the manufacture of a medicament to treat or prevent togaviral infection, or to ameliorate or reduce one or more symptoms of a togaviral infection, in a subject suffering from or susceptible to the togaviral infection, In formula (I): Q1 is -C(R1)2- or -C(O)-; Q2 is -C(R1)2, -C(R1)(Y)-, -C(Y)- or CH2-CH2-; Q3 is -H or -C(R1)3-; Q4 is -C(R1)2-, -C(O)-, hydroxyvinylidine or methyl methylene; Q5 is -C(R1)2- or -C(O)-; Q6 is H, CH2OH or -C(R1)3- X and Y independently are -OH, -H, alkyl, -O-C(O)-R5, -C(O)-OR5, halogen or when a double bond exits between position 11 and -X, X is =O; each R1 independently is -H, halogen, -OH, alkoxy, or alkyl or at position 3 R1 is additionally OR53; R2 is-H, -OH, halogen, alkyl, alkoxy, -OR3, a fatty acid, alkynyl, (J)n-phenyl=alkyl, (J)n-phenyl-alkenyl, an ester, or -S- C(O)-(CH2)m-R4, -C(O)-S-(CH2)m-R4, -O-S(O)(O)-(CH2)m-R4, -O-S(O)(O)-O-(CH2)m-R4, -O-C(O)-NH-(CH2)m-R4, -NH-C(O)-O-(CH2)m-R4, -O-C(S)-(CH2)m-R4, -C(S)-O-(CH2)m-R4 or R2, together with the R1 that is bonded to the same carbon atom is =O; m is 0 to 3; R53, R3, R4, R5 are as defined in the specification and the dotted lines represent an optional double bond, provided that there are not double bonds at both the 4-5 and 5-6 positions and provided that when a double bond is present optionally an R1 group is bonded to carbon atoms at the 1-, 2-, 4-, 5- or -6 positions to satisfy the tetravalency of these carbon atoms provided that the compound is not dehydroepiandrosterone, dehydroepiandrosterone-3b-sulphate, 3b, 7b-dihydroandrost- 5-one or an ester or ether of any of these compounds..
Patent NZ-521291-A (NZ)
Title: Estrogen agonist/antagonist metabolites
Inventor: DAY WESLEY WARREN
IPC: C07D207/26
Filed: 2001-03-19
Abstract: Mammalian metabolites of the estrogen agonist/antagonist (-)-cis-6-phenyl-5-[4-(2-pyrrolidin-1-yl- ethoxy)-phenyl]-5,6,7,8-tetrahydronaphthalene-2-ol (PPTN) of formula (I), useful in the treatment of disease and pharmaceutical compositions containing the compounds.
Patent NZ-526015-A (NZ)
Title: Pharmaceutical preparation comprising an active dispersed on a matrix
Inventor: DIETRICH RANGO
IPC: A61K31/4439
Filed: 2001-12-06
Abstract: A preparation is described in which an active ingredient selected from the group of PDE 4 inhibitors is essentially uniformly dispersed or dissolved in an excipient matrix composed of one or more excipients selected from the group of fatty alcohol, triglyceride, partial glyceride and fatty acid ester. The preparation is disclosed to be in the form of microspheres having particle size in the range of 50-500 mum. A method of manufacturing the preparation comprises the step of prilling a solution or dispersion of the active ingredient in the melt of the excipients using a vibrating nozzle.
Patent NZ-526519-A (NZ)
Title: Determining the ratio of genomic DNA and mtDNA or their related gene products with regards to determining the stage of an asymptomatic disease
Inventor: VAN GEMEN BOB
IPC: C12Q1/68
Filed: 2001-12-04
Abstract: Described is the diagnosis of disease or the determination of functioning of cellular organisms, being of multi-cellular or unicellular nature, being visible by the naked eye or being a micro-organism. Also provided is a method for determining functioning of a cellular organism comprising determining the relative ratio of a first endosymbiont cellular organelle nucleic acid and/or gene product thereof in a sample obtained from the organism in relation to the amount of a second nucleic acid and/or gene product thereof.
Patent NZ-530824-A (NZ)
Title: 4-amino-6-phenyl-pyrrolo[2,3-d]pyrimidine derivatives
Inventor: BOLD GUIDO
IPC: C07D487/04
Filed: 2002-08-06
Abstract: Disclosed are compounds of the formula (I); wherein R1 and R2 are each independently of the other hydrogen, unsubstituted or substituted alkyl or cycloalkyl, a heterocyclic radical bonded via a ring carbon atom, or a radical of the formula R4-Y-(C=Z)- wherein R4 is unsubstituted, mono- or disubstituted amino or a heterocyclic radical, Y is either not present or lower alkyl and Z is oxygen, sulfur or imino, with the proviso that R1 and R2 are not both hydrogen; or R1 and R2 together with the nitrogen atom to which they are attached form a heterocyclic radical; R3 is a heterocyclic radical or an unsubstituted or substituted aromatic radical; G is C1-C7-alkylene, -C(=O)-, or C1-C6-alkylene wherein the carbonyl group is attached to the NR1R2 moiety; Q is -NH- or -O-, with the proviso that Q is -O- if G is -C(=O)- or C1-C6-alkylene-C(=O)-; and X is either not present or C1-C7alkylene, with the proviso that a heterocyclic radical R3 is bonded via a ring carbon atom if X is not present; or a salt thereof. Further disclosed is a process for the production of compounds of the formula (I) and the use of those compounds or their salts in the manufacture of a medicament.
Patent NZ-531203-A (NZ)
Title: Multi-edged cutter for use with a strapping tool.
Inventor: CRITTENDEN DAVID E
IPC: B21F11/00
Filed: 2004-02-18
Abstract: A cutting mechanism for use with a strapping tool is disclosed. The cutter is configured for receipt in a die holder mounted to the strapping tool. The cutter comprises a body portion having a polygonal cross-sectional configuration. The cutter has a pair of opposing, mirror image cutting surfaces defining a pair of opposing, mirror image elongated cutting edges, being an in-use cutting edge and a spare cutting edge. The cutter has a plurality of retaining notches formed therein to secure the body portion with the die holder surfaces. The cutter being reversible on the die holder such that the in-use and spare cutting edges are interchangeable by rotation of the cutter.
Patent NZ-533581-A (NZ)
Title: Washing machine drum
Inventor: NITSCHE ALFRED
IPC: D06F37/02
Filed: 2002-08-21
Abstract: The invention relates to a drum (1) designed for high-speed spinning of damp linen. Said drum comprises a rotating drum shell (2), which is curved from a thin-walled material strip to form a cylinder, so that the parallel end edges (3) and (4) of said material strip contact to form a joint line (5). So that said drum may resist drum speeds higher than 1,500 rpm, the end edges (3) and (4) have a slot-shaped teething (6 to 9). The teeth (6) and (7) of said teething engage into the respective tooth gaps (8) and (9) of the opposite end edge, so that the base lines (11) of said tooth gaps (8, 9) meet to form an at least approximately straight line and so that the teeth (6, 7) are fitted into the non-toothed zone (8, 9) of the end edge (3, 4) outside of the drum above the material strip, each tooth being firmly secured to the respective non-toothed zone (8, 9).
Patent NZ-534408-A (NZ)
Title: A remote asset valuation system
Inventor: GEDEON RON
Filed: 2004-07-29
Abstract: A system for constructing an asset valuation includes a portable device (1) capable of receiving input information with respect to an asset to be valued, and transmitting the input information to a server (6,7). The server (6,7) is arranged to receive the input information, and collates this information with historical information from a database (8). The collated information is thus formatted into an asset valuation in a format that is compatible with the requirements of an end user.