baber/WOPTO huggingface dataset:
Patent WO-2021138559-A1 (WO)
Title: Improved aav-abcd1 constructs and use for treatment or prevention of adrenoleukodystrophy (ald) and/or adrenomyeloneuropathy (amn)
Inventor: CLARK SEAN
IPC: C12N7/00
Filed: 2020-12-31
Abstract: The present disclosure generally relates to polynucleotides and AAV vectors that provide for the expression of ALD protein in target (e.g., neurons or glial) cells when administered to subjects in need thereof. The present disclosure further relates to compositions comprising such a polynucleotide or vector. These polynucleotides, vectors, and compositions may be used for the treatment and prevention of ALD or AMN in subjects in need thereof.
Patent WO-2021150455-A1 (WO)
Title: Transceiver circuit with digital pre-distortion (dpd) options
Inventor: DANTONI FRANCESCO
IPC: H03F1/26
Filed: 2021-01-18
Abstract: A system (100) includes: a host processor (102); a transceiver (104) coupled to the host processor (102); and a power amplifier (126A-126N) coupled to an output of the transceiver (104). The transceiver (104) includes a transmit chain with digital pre-distortion (DPD) logic configured to: perform DPD correction operations on transmit data (107) received by the transmit chain; and output corrected transmit data (109A-109N) based on the performed DPD correction operations, wherein the output corrected transmit data (109A-109N) is provided to the power amplifier (126A-126N).
Patent WO-2021154764-A1 (WO)
Title: Tandem mass tag multiplexed quantitation of post-translational modifications of proteins
Inventor: MAO YUAN
IPC: G01N33/68
Filed: 2021-01-26
Abstract: Disclosed are methods of quantifying multiple quality attributes, such as post translational modifications, of multiple samples in a single mass spectrometry (MS) run, including contacting two or more samples with a digesting solution under conditions sufficient to digest samples, wherein each sample is digested separately and the digesting solution is a Tris-free buffer solution; contacting each of the two or more digested samples with a specific Tandem Mass Tag (TMT) labeling reagent under conditions sufficient to label peptides within each of the digested samples with the specific TMT labeling reagent; quenching labeling of peptides within each of the two or more digested samples; combining equal volumes of the two or more labeled, digested samples into a single combined sample solution; and analyzing the single combined sample solution by targeted mass spectral analysis, thereby allowing multiple quality attributes of the two or more samples to be quantified in a single mass spectrometry (MS) run.
Patent WO-2021188216-A1 (WO)
Inventor: VASKO RUDOLF P
IPC: B24B19/14
Filed: 2021-02-01
Abstract: L'invention concerne un dispositif de commande destiné à être utilisé dans la commande d'un système d'affûtage de lame qui comprend au moins une roue de meulage utilisable pour affûter la lame. Le dispositif de commande comprend un dispositif de mémoire et un processeur couplé en communication au dispositif de mémoire. Le processeur est configuré pour recevoir des signaux provenant d'au moins un capteur, ledit capteur pouvant fonctionner pour surveiller la rotation de ladite roue de meulage. Le processeur est en outre configuré pour régler une position de ladite roue de meulage par rapport à la lame sur la base des signaux reçus.
Patent WO-2021167826-A1 (WO)
Inventor: PETERS RICHARD
IPC: B65D65/46
Filed: 2021-02-11
Abstract: Une fermeture monobloc 10 comprend des première et seconde parties de fermeture 10a, 10b. La première partie de fermeture 10a comprend une partie paroi supérieure 12 et une partie jupe annulaire 14 dépendant de la partie paroi supérieure. La partie jupe annulaire comprend une formation de filetage interne pour une mise en prise homologue avec une formation de filetage externe d'un récipient. La seconde partie de fermeture comprend une bande inviolable 18. La bande inviolable dépend de la partie jupe annulaire, et est partiellement reliée amovible à celle-ci, au moyen d'une première liaison fragile. La fermeture comprend un matériau polymère et un produit de remplissage des trous.
Patent WO-2021188328-A1 (WO)
Title: Roller bearing with axially-fixed, rotatable rib flange
Inventor: AI XIAOLAN
IPC: F16C33/58
Filed: 2021-03-10
Abstract: A bearing includes an inner ring having first and second raceways, an outer ring having a raceway, a first row of rolling elements positioned to roll on the first raceway of the inner ring and the raceway of the outer ring, and a second row of rolling elements positioned to roll on the second raceway of the inner ring and the raceway of the outer ring. A cage maintains relative spacing of the first row and the second row of rolling elements. A rib ring is positioned between the first and second raceways of the inner ring, the rib ring being rotatable relative to the inner ring and axially constrained relative to the inner ring.
Patent WO-2021183910-A1 (WO)
Title: Generation of autoimmune inhibitory t cells by fibroblast mediated education
Inventor: ICHIM THOMAS
IPC: A61K35/33
Filed: 2021-03-12
Abstract: Disclosed are means, methods, and compositions of matter useful for treatment of autoimmunity comprising exposing patient T cells fibroblasts possessing tolerogenic properties. In one embodiment peripheral blood mononuclear cells are cultured in the presence of CD73 selected fibroblasts alone or in the presence of interleukin-2, and/or IL-7, and/or TGF-beta, and/or PGE-2 for a period of time sufficient to endow tolerogenic properties. Said tolerogenic properties include ability to suppress adaptive or innate immune responses. In another embodiment the disclosure provides methods of generating antigen specific immune regulatory cells by culture of T cells together with fibroblasts in the presence of antigen to which specific immune regulation is desired.
Patent WO-2021202264-A1 (WO)
Inventor: LI NAN
IPC: G01N21/01
Filed: 2021-03-26
Abstract: Système de surveillance électronique et optique d'échantillons biologiques, le système comprenant : une plaque à puits multiples comprenant une pluralité de puits conçus pour recevoir une pluralité d'échantillons biologiques, chacun des puits comprenant un ensemble d'électrodes et une fenêtre transparente sur une surface inférieure du puits qui est exempt d'électrodes; un module d'éclairage conçu pour éclairer les puits; un berceau conçu pour recevoir la plaque à puits multiples, le berceau comprenant une ouverture sur le fond qui expose les fenêtres transparentes des puits; et un module d'imagerie optique mobile à travers différents puits d'une même plaque à puits multiples pour capturer des images à travers les fenêtres.
Patent WO-2022211804-A1 (WO)
Inventor: TREXLER JONATHAN
IPC: A61M35/00
Filed: 2021-03-31
Abstract: Vibrational powder applicators and related methods are disclosed. In some embodiments, a vibrational powder applicator may include a powder storage chamber, a powder (e.g., a therapeutic powder) disposed within the powder storage chamber, an actuator operatively coupled to the powder storage chamber and configured to vibrationally agitate the powder when activated, and an outlet in fluid communication with the powder storage chamber. In some embodiments, a vibrational powder applicator may include a flow restrictor and/or a valve.
Patent WO-2021216553-A1 (WO)
Inventor: GASPARD DAN S
IPC: A23L27/30
Filed: 2021-04-20
Abstract: Various aspects of the present invention relate to steviol glycoside extraction. A method of treating a stevia extract that includes steviol glycosides and/or salts thereof, and malonated steviol glycosides and/or salts thereof, includes treating the stevia extract at a pH greater than 10 to convert at least some of the malonated steviol glycosides and/or salts thereof to non-malonated steviol glycosides and/or salts thereof, to produce a modified stevia extract. The method includes decreasing the pH of the modified stevia extract to a pH of less than 9 to provide a pH-adjusted modified stevia extract. The method also includes recovering the steviol glycosides and/or salts thereof from the pH-adjusted modified stevia extract, the recovered steviol glycosides and/or salts thereof including the non-malonated steviol glycosides and/or salts thereof.
Patent WO-2021216867-A1 (WO)
Inventor: TIMKEN HYE-KYUNG
IPC: C10G1/00
Filed: 2021-04-22
Abstract: Provided in one embodiment is a continuous process for converting waste plastic comprising polyethylene and/or polypropylene into recycle for polyethylene polymerization. The process comprises selecting waste plastics containing polyethylene, polypropylene, or a mixture thereof, and passing the waste plastics through a pyrolysis reactor to thermally crack at least a portion of the polyolefin waste and produce a pyrolyzed effluent. The pyrolyzed effluent is separated into offgas, a pyrolysis oil comprising a naphtha, diesel and heavy fractions, and char. The pyrolysis oil, or at least a fraction, is passed to a filtration/metal oxide treatment, with the treated product passed to a refinery FCC unit. A liquid petroleum gas C 3  olefin/paraffin mixture fraction is recovered from the FCC unit, as well as a C 4  olefin/paraffin mixture fraction. The liquid petroleum gas C 3  olefin/paraffin mixture fraction is passed to a steam cracker for ethylene production.
Patent WO-2021231063-A1 (WO)
Title: Load balancing communication sessions in a networked computing environment
Inventor: MESTERY KYLE
IPC: H04L45/42
Filed: 2021-04-23
Abstract: Techniques for load balancing communication sessions in a networked computing environment are described herein. The techniques may include establishing a first communication session between a client device and a first computing resource of a networked computing environment. Additionally, the techniques may include storing, in a data store, data indicating that the first communication session is associated with the first computing resource. The techniques may further include receiving, at a second computing resource of the networked computing environment, traffic associated with a second communication session that was sent by the client device, and based at least in part on accessing the data stored in the data store, establishing a traffic redirect such that the traffic and additional traffic associated with the second communication session is sent from the second computing resource to the first computing resource.
Patent WO-2022035474-A1 (WO)
Inventor: WARDHAN UTTKARSH
IPC: G06F11/30
Filed: 2021-04-23
Abstract: The reliability of a data communication link may be analyzed and otherwise maintained by collecting a two-dimensional array representing a functional data eye, and using a convolutional neural network to determine a score of the functional data eye. The determined score may be compared with a threshold, and an action may be initiated based on the result of the comparison.
Patent WO-2021222883-A1 (WO)
Inventor: DETTORE ROBERT M
IPC: A41D13/11
Filed: 2021-05-03
Abstract: A protective mask having a valve assembly that allow a user to drink a beverage while wearing the mask to maintain a safe environment by filtering contaminants, such as pathogens and particles from passing through the mask. The valve assembly may be provided on the mask or may be separately provided for attachment to a mask. The protective mask with the valve assembly has an attachment portion that allows common beverage straws to connect with the valve assembly to allow liquids to be draw through the mask by a user through a passageway. A check valve limits liquid flow in a single direction and actuates to open the valve when a user draws in liquid through the mouthpiece. The valve remains closed and blocks passage of inhaled or exhaled air, and blocks liquid flow in the direction opposite of the flow direction.
Patent WO-2021225995-A1 (WO)
Title: Quick check gauge for electrical transmission and distribution line installation
Inventor: MORRIS RONALD
IPC: G01B3/38
Filed: 2021-05-03
Abstract: A quick check gauge to check an adequacy and precision of a crimped and compression region of an accessory onto an electrical conductor. The quick check gauge comprises a first leg, a second leg, and a base. The first leg includes a first inner edge. The second leg includes a second inner edge that is substantially parallel to the first inner edge. The base includes a grasping region and an inner edge that together with the first leg and the second leg define a cavity, the cavity having a width that corresponds to a properly crimped accessory. The crimped and compression region of the accessory is determined to be insufficient when the crimped and compression region is incapable of being inserted into the cavity.
Patent WO-2021226125-A1 (WO)
Title: Tone reservation for peak to average power ratio reduction
Inventor: SAHRAEI SAEID
IPC: H04L27/26
Filed: 2021-05-04
Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a user equipment may receive a resource allocation indicating a plurality of transmission tones comprising a subset of data tones of a plurality of data tones and a subset of peak reduction tones (PRTs) of a plurality of PRTs, wherein the resource allocation indicates a plurality of data tone locations and a plurality of PRT locations within a particular bandwidth, wherein a subset of PRT locations of the plurality of PRT locations are arranged relative to a subset of data tone locations of the plurality of data tone locations according to a PRT sequence corresponding to a set of allocated frequency resources; and transmit a data transmission using a waveform based at least in part on the resource allocation. Numerous other aspects are provided.
Patent WO-2021242619-A1 (WO)
Title: Polymer formulations and irrigation tubing including polymer formulations
Inventor: BARBOSA FELIPE
IPC: C08L23/08
Filed: 2021-05-21
Abstract: Embodiments of polyethylene formulations and articles comprising polyethylene formulations are dislcosed. The polyethylene formulation may include from 45 wt.% to 90 wt.% of an MDPE having a density of from 0.930 g/cc to 0.950 g/cc and a melt index (I 2 ) from 0.05 g/10 min to 0.5 g/10 min; from 10 wt.% to 50 wt.% of a polyethylene composition having a density from 0.910 g/cc to 0.936 g/cc and a melt index (I 2 ) from 0.7 g/10 min to 1.0 g/10 min; and from 0.5 wt.% to 5% of a masterbatch composition. The polyethylene composition may comprise a first polyethylene fraction area in a temperature range of 45°C to 87°C of an elution profile via improved comonomer composition distribution (iCCD) analysis method and a second polyethylene fraction area in a temperature range of 95°C to 120°C of an elution profile via iCCD.
Patent WO-2021243191-A1 (WO)
Inventor: TAYLOR ANDREW J
IPC: B62B7/06
Filed: 2021-05-28
Abstract: Un système de poussette pour enfant peut permettre de passer du transport d'un seul enfant au transport de deux enfants sans retirer un premier appareil de transport d'enfant de la poussette et sans ajouter d'adaptateurs à la poussette. Les deux appareils de transport d'enfant peuvent être repositionnés par rapport au châssis de la poussette lorsqu'ils sont montés sur la poussette. Un panier auxiliaire autoportant et pliable peut être monté sur la poussette à la place de l'un des appareils de transport d'enfant.
Patent WO-2022076042-A1 (WO)
Title: Procédé et appareil de service en nuage
Inventor: IRAJ SODAGAR
IPC: G06F9/48
Filed: 2021-06-10
Abstract: Des aspects de la présente invention concernent des procédés et des appareils de traitement de contenu multimédia basé sur un réseau. Par exemple, un appareil en nuage pour un traitement de contenu multimédia basé sur un réseau (NBMP) comprend un ensemble de circuits de traitement. L'ensemble de circuits de traitement reçoit des informations associées à une entité dans le nuage pour un NBMP. L'ensemble de circuits de traitement obtient un identifiant d'entité de NBMP à partir des informations associées à l'entité. Ensuite, l'ensemble de circuits de traitement interprète les informations associées à l'entité sur la base de l'identifiant d'entité de NBMP.
Patent WO-2021263018-A1 (WO)
Inventor: KESHAVARZI MOHAMMAD
IPC: G06T17/00
Filed: 2021-06-24
Abstract: A method of augmenting scenes with virtual objects includes accessing a target scene, extracting features from the target scene into a spatial scene graph representation of the target scene, generating one or more datasets from the spatial scene graph representation, using machine learning system to iteratively operate on the one or more datasets to by sampling positions and orientations in the target scene to create a probability map for placement of a virtual object in the scene, and predicting a viable placement for the virtual object in the target scene, producing a final scene.
Patent WO-2021263059-A1 (WO)
Inventor: LAWRENCE BENJAMIN
IPC: H05K3/28
Filed: 2021-06-24
Abstract: A plasma ashing system includes a plasma generator configured to generate a plasma from a gas source. The system further includes a plasma reaction chamber configured to house a substrate comprising a Parylene coating, wherein the plasma reaction chamber is configured to expose surfaces of the Parylene coating on the substrate to the plasma, wherein the plasma is configured to remove portions of the Parylene coating on the substrate. The system further includes a masking fixture including at least one opening and configured to shield areas of the substrate from plasma ashing, and further including a gasket between the masking fixture and the substrate.
Patent WO-2022046321-A1 (WO)
Title: Method, system, and storage medium for autonomous vehicle route blockage detection
Inventor: PASSA NITIN
IPC: G08G1/01
Filed: 2021-07-20
Abstract: The subject disclosure relates to solutions for arbitrating traffic blockages along vehicle routes. In some aspects, the disclosed technology encompasses a method including steps for determining a vehicle route, wherein the vehicle route comprises at least one lane plan to be followed by an autonomous vehicle (AV), identifying a blockage along the vehicle route, analyzing the blockage to determine if the blockage constitutes a persistent blockage, and if the blockage constitutes a persistent blockage, associating a time value with the blockage. Systems and machine-readable media are also provided.
Patent WO-2023009108-A1 (WO)
Title: Système et procédé d'optimisation de terminal de paiement
Inventor: CHIU KASEY
IPC: G06Q20/00
Filed: 2021-07-28
Abstract: Un système comprend un processeur et un support lisible par ordinateur non transitoire couplé au processeur. Le support lisible par ordinateur non transitoire comprend un code, qui, lorsqu'il est exécuté par le processeur, amène le processeur à recevoir une entrée provenant d'un utilisateur d'un dispositif utilisateur pour générer un emplacement de paiement optimal sur un dispositif d'affichage d'application, générer une première limite de l'emplacement de paiement optimal sur l'affichage d'application du dispositif utilisateur sur la base d'un premier mouvement d'une carte activée par paiement dans une première direction et générer une seconde limite de l'emplacement de paiement optimal sur l'affichage d'application du dispositif utilisateur sur la base d'un second mouvement de la carte activée par paiement dans une seconde direction. La première limite et la seconde limite se combinent pour former des bords de définition de l'emplacement de paiement optimal.
Patent WO-2022040280-A1 (WO)
Inventor: KING MICHAEL R
IPC: A23K10/18
Filed: 2021-08-18
Abstract: The invention relates to direct-fed microbials for use in  E. coli  inhibition in animals in combination with enrofloxacin. More particularly, the invention relates to isolated  Bacillus  strains 9, 57, 71, and 126, and strains having all of the identifying characteristics of these strains, for a use comprising the above-mentioned use.
Patent WO-2023033837-A1 (WO)
Title: Seringue dotée d'une capacité combinée de verrouillage luer et de fixation d'aiguille de stylo
Inventor: WHITNEY DES
IPC: A61M5/34
Filed: 2021-09-03
Abstract: Un raccord mâle sans aiguille ayant une pointe allongée effilée et une collerette conforme aux normes ISO, la collerette ayant une surface de paroi latérale externe avec une pluralité de filetages pour une connexion à des filetages internes correspondants d'une aiguille de stylo. Le raccord mâle sans aiguille a une conicité entre une extrémité distale de la pointe allongée et une paroi latérale interne de la pointe allongée. Le raccord mâle sans aiguille est configuré pour recevoir une aiguille de stylo.
Patent WO-2022066914-A1 (WO)
Inventor: DRUMMOND VIRGINIA
IPC: H04M1/72457
Filed: 2021-09-23
Abstract: In one or more implementations, a user of a client application may share the location of the user in relation to an avatar of the user. In various examples, an avatar-based location sharing user interface element may be selectable to execute an augmented reality content item that is executable to make the location of the user accessible to one or more additional users of the client application. In one or more examples, a message may be generated that includes user content captured at a location of the user, an avatar of the user, and location information related to the location of the user. In one or more additional examples, the location of the user may be accessible via a map user interface that displays the avatar of the user at the location of the user within a geographic region.
Patent WO-2023055350-A1 (WO)
Title: Spring-assist module for boom barrier, boom barrier system, and associated methods
Inventor: LAMORE MICHAEL
IPC: E01F13/06
Filed: 2021-09-29
Abstract: A boom barrier includes a boom arm and a spring-assist module configured to assist with pivoting the boom arm. The boom arm can be pivoted upwardly to an upper position in response to torque being applied in a first direction to the boom arm. The boom arm can be pivoted downwardly to a lower position in response to torque being applied in a second direction to the boom arm. The spring-assist module can apply torque in the first direction to the boom arm when the boom arm is in the lower position and an adjacent range of intermediate positions to assist with pivoting the boom barrier upwardly and/or the spring-assist module can apply torque in the second direction to the boom arm when the boom arm is in the upper position and an adjacent range of intermediate positions to assist with pivoting the boom arm downwardly.
Patent WO-2022076357-A1 (WO)
Inventor: SABHARWAL AAKASH
IPC: G06Q30/06
Filed: 2021-10-05
Abstract: A unified system with a machine learning feature data pipeline that can be shared among various product areas or teams of an electronic platform is described. A set of features can be fetched from multiple feature sources. The set of features can be combined with browsing event data to generate combined data. The combined data can be sampled to generate sampled data. The sampled data can be presented in a format having a structure that is agnostic to a feature source from which the set of features was fetched. The sampled data can be joined with old features by a backfilling process to generate training data designed to train one or more machine learning models. Related methods, apparatuses, articles of manufacture, and computer program products are also described.
Patent WO-2022081739-A1 (WO)
Inventor: MILLS JAMES EDWARD
IPC: A61K31/519
Filed: 2021-10-13
Abstract: L'invention concerne des composés de formule (I') ou (I) ci-dessous, ou des sels pharmaceutiquement acceptables de ceux-ci, ainsi que des procédés pour leur utilisation et leur production.