baber/WOPTO huggingface dataset:
Patent IL-81117-A0 (IL)
Title: Pyrimido(5,4-b)(1,4)oxazine derivatives,their preparation and pharmaceutical compositions containing them
IPC: A61K31/535
Filed: 1986-12-30
Abstract: The invention relates to novel pyrimido [5,4-b][1,4]oxazine derivatives of the formula (I), and the acid addition salts thereof, pharmaceutical compositions containing them and a process for their preparation. In the formula (I)    <IMAGE>  (I)  wherein R1 stands for a C1-4 alkyl group; R2 stands for hydrogen or halogen or an azido group or an -NR5R6 group, wherein R5 represents hydrogen or a benzyl group, or a C1-4 alkyl group unsubstituted or substituted by a hydroxyl group, R6 stands for hydrogen, an amino group, a C3-6 cycloalkyl group, a straight or branched-chain C1-4 alkyl group optionally substituted by a hydroxyl, mercapto, aminocarbonyl, furyl, 2-benzo[1,4]dioxanyl, di(C1-4 alkyl)amino group or by a phenyl or phenoxy group optionally mono- or polysubstituted by halogen or C1-4 alkoxy group (s) or by a 6-membered, saturated nitrogen-containing heterocycle optionally containing an additional nitrogen or oxygen atom and optionally substituted by a C1-4 alkyl or benzyl group; further NR5R6 may also represents a 6-membered, saturated, nitrogen-containing heterocycle optionally containing an additional nitrogen or oxygen atom and optionally substituted by a C2-4 alkoxycarbonyl or C1-4 hydroxyalkyl group; R3 and R4 are the same or different and stand for hydrogen or a C1-4 alkyl group; R9 stands for hydrogen or a C1-4 alkyl group unsubstituted or monosubstituted by an oxo, cyano, aminocarbonyl, C2-5 alkoxycarbonyl, pyridiyl, morpholinocarbonyl, or phenyl group or mono- or polysubstituted by OH group(s), with the proviso that R2 is different from chlorine, 4-morpholinyl and piperidyl group when R9 stands for hydrogen; or R2 is different from chlorine and 4-morpholinyl group when R9 stands for a methyl or benzyl group. The compounds of the formula (I) are capable to increase the myocardial contractile force (the performance of the failing heart) and the coronary blood flow, thus they can therapeutically be used for the treatment of the chronic heart failure and coronary disturbances.
Patent IL-88180-A0 (IL)
Title: Pesticide composition comprising pyrethroids with phosphoric acids
IPC: A01N53/02
Filed: 1988-10-27
Abstract: The present invention relates to a multi-component pesticidal composition against arthropoda containing as active ingredient pyrethroides and phosphate esters and optionally piperonyl butoxide and excipients comprising as pyrethroid component 0.1 to 40 percent by weight of cypermethrin related to the total weight comprising out of the 8 possible isomers 40 to 100 percent by weight of 1RcisS and/or 1RtransS stereoisomer and as a second component at least one phosphoric acid, thiophosphoric acid or dithiophosphate being toxic on arthropoda at a ratio of 1:1-99 related to the amount of cypermethrin.
Patent IL-93586-A0 (IL)
Title: N-substituted aminoalkane-diphosphonic acids
IPC: C07F9/58
Filed: 1990-03-01
Abstract: Compounds of the formula I   <IMAGE> (I)  in which R1 is an aromatic radical, n is 0, 1, 2 or 3, X is an oxy group, a thio group which can be oxidized or an imino group which is unsubstituted or has aliphatic substituents, alk1 and alk2 are identical or different divalent aliphatic radicals, and R2 is hydrogen or a monovalent aliphatic radical and salts thereof have properties which regulate calcium metabolism and can be employed for the treatment of diseases connected with disturbances in this metabolism. They are prepared, for example, by reacting a compound of the formula   <IMAGE> (V)  in which X3 is carboxyl with a phosphorylating agent and hydrolysing the primary product.
Patent FI-20021923-A0 (FI)
Inventor: KURKINEN LEO
IPC: B05C11/10
Filed: 2002-10-29
Abstract: A cross component (14,14'14), formed into a box-type sheet metal structure, substantially extends across the entire width of a web (11) and end components (15) to which the cross component is attached.
Patent FI-20105370-A0 (FI)
Inventor: BACKLUND LEIF
IPC: B63B/
Filed: 2010-04-09
Abstract: A method for operating an LNG fuelled marine vessel having a propulsion system, a power plant and an LNG storage tank, whereby LNG is supplied as a gas fuel from the LNG storage tank to the power plant. The marine vessel deploys a fixed LNG storage tank and a removable LNG storage tank on board the marine vessel. In order to facilitate bunkering, the removable LNG storage tank is removed and replaced by another removable LNG storage tank at a bunkering facility.
Patent IL-100055-A0 (IL)
Title: Chemical process
IPC: A61P17/00
Filed: 1991-11-14
Abstract: A process for the preparation of a 3-alkylated indole, which comprises:-   a) reacting a N-(2-nitrostyryl) enamine with an alkylating agent to afford an imine salt, b) optionally reacting the imine salt with water to afford a (2-nitrophenyl)acetaldehyde, and c) reacting the imine salt or the (2-nitrophenyl)acetaldehyde with a reducing agent capable of selectively reducing the nitro group, to afford the desired 3-alkylated indole. a
Patent IL-108449-A0 (IL)
Title: Compositions and methods for delivery of genetic material
IPC: A61K39/205
Filed: 1994-01-26
Abstract: Methods of introducing genetic material into cells of an individual and compositions and kits for practicing the same are disclosed. The methods comprise the steps of contacting cells of an individual with a polynucleotide function enhancer and administering to the cells, a nucleic acid molecule that is free of retroviral particles. The nucleic acid molecule comprises a nucleotide sequence that encodes a protein that comprises at least one epitope that is identical or substantially similar to an epitope of a pathogen antigen or an antigen associated with a hyperproliferative or autoimmune disease, a protein otherwise missing from the individual due to a missing, non-functional or partially functioning gene, or a protein that produces a therapeutic effect on an individual. Methods of prophylactically and therapeutically immunizing an individual against HIV am disclosed. Pharmaceutical compositions and kits for practicing methods of the present invention are disclosed.
Patent IL-122944-A0 (IL)
Title: Halogenobenzimidazoles and their preparation
IPC: C07D413/14
Filed: 1996-07-29
Abstract: PCT No. PCT/EP96/03334 Sec. 371 Date Jan. 28, 1998 Sec. 102(e) Date Jan. 28, 1998 PCT Filed Jul. 29, 1996 PCT Pub. No. WO97/06171 PCT Pub. Date Feb. 20, 1997New halogenobenzimidazoles of the formula in which A, R1, R2, R3, R4 and X have the meanings given in the description, and their acid addition salts and metal salt complexes, a process for their preparation and their use as microbicides in crop protection and in the protection of materials. New intermediates of the formula in which R12-R17 and X have the meanings given in the description, and processes for the preparation of these substances.
Patent IL-125708-A0 (IL)
Title: Shaft phase control mechanism
IPC: B64C27/54
Filed: 1996-11-28
Abstract: The phase control mechanism includes first gears (3,4) coupled to the output shafts (2,1a) which are to be phase controlled. A Transfer gear (5) is provided for rotation or operation independent of the input and is coupled to the first gears (3,4) to allow rotary motion to be transferred between the first gear members (3,4) and a phase adjuster (10,17) causes the first gears (3,4) to advance on regress relative to one another to change the phase relationship between the outputs. <IMAGE>
Patent IL-126251-A0 (IL)
Title: A layered system for application of an active substance-releasing layer of small thickness and processes for the production thereof
IPC: A61K9/70
Filed: 1997-03-12
Abstract: PCT No. PCT/EP97/01252 Sec. 371 Date Apr. 26, 1999 Sec. 102(e) Date Apr. 26, 1999 PCT Filed Mar. 12, 1997 PCT Pub. No. WO97/35564 PCT Pub. Date Oct. 2, 1997A transdermal therapeutic system for the release of active substances to a substrate is characterized by the structure of the system comprising a substrate (1) provided with a separating layer (2), a film layer (3) comprising the active substance, and a protective layer (4) provided with a nonstick finish, the separating layer (2) consisting of a material whose bond to the film layer (3) may be abolished. By means of printing methods, such systems having small application thickness and high flexibility can be manufactured, it being possible to provide a substrate that has been rendered adhesive as an alternative to the substrate/separating layer-complex. A printing method limiting the active substance-containing region to the application site reduces disposal problems.
Patent IL-130017-A0 (IL)
Title: Packaging for smoking articles
IPC: B65D75/58
Filed: 1997-11-19
Abstract: PCT No. PCT/GB97/03183 Sec. 371 Date May 12, 1999 Sec. 102(e) Date May 12, 1999 PCT Filed Nov. 19, 1997 PCT Pub. No. WO98/22367 PCT Pub. Date May 28, 1998A pack (1) for smoking articles such as cigarettes has a sealed enclosure of barrier material, with a resealable access aperture to the enclosure. A cover (7) over that aperture has on all its openable edges a permanently tacky surface overlapping over the barrier material there. The cover has a non-adhesive tab (10) to assist opening. An inner frame provides support to the barrier material adjacent to the aperture, allowing the adhesive cover to be pressed firmly against the barrier layer to aid resealing. The pack may be provided with or without an outer carton. If an outer carton is included, the carton may be of a generally rigid card material, and may have a flip-top configuration, may be a Laub+E,acu e+EE  box, or may have a shell-and-slide configuration. An inner frame provides support to the barrier material adjacent to the aperture, allowing the adhesive cover to be pressed firmly against the barrier layer to aid resealing. The pack may be provided with or without an outer carton. If an outer carton is included, the carton may be of a generally rigid card material, and may have a flip-top configuration, may be a Laub+E,acu e+EE  box, or may have a shell-and-slide configuration.
Patent IL-140432-A0 (IL)
Title: Method for manufacturing confectionary bars
IPC: A23G3/12
Filed: 2000-12-20
Abstract: Confectionery bar manufacturing procedure consists of covering a core (3) e.g. for wafer or biscuit with a layer of a cooked sugar product (8) such as caramel, marshmallow or nougat topped with nuts, cereal or dried fruit (90) before coating with chocolate. The procedure consists of covering a core (3) e.g. for wafer or biscuit with a layer of a cooked sugar product (8) such as caramel, marshmallow or nougat topped with nuts, cereal or dried fruit (90) before coating with chocolate. As the core passes along a conveyor (20) the cooked sugar layer is applies to it from a cooling roller (4) so that it moulds to the shape of the top and sides of the core. The topping (90) is applied to the cooked sugar layer on the roller, and the bars are cut to length at the outlet end of the conveyor before coating with chocolate.
Patent IL-141817-A0 (IL)
Title: Non-wire contact device application for cryptographic module interfaces
IPC: G06F21/00
Filed: 2001-03-05
Abstract: Conventional approaches to cryptographic modules interface design have achieved only limited physical security. Embodiments of the present invention encompass non-contact interfaces to cryptographic modules. Non-contact inputs comprise such inputs as contain magnetic coupling, RF coupling, infrared coupling, optical coupling and acoustical coupling to load cryptographic data into cryptographic modules. By using non-contact methods of coupling, the physical inputs to the module can be hidden as no external connectors to input cryptographic data are required. In addition, several non-contact inputs can be disposed within a cryptographic module. These non-contact inputs may have orientations and spacings, which require the specific placement of transmitting units, thereby increasing the security of the module. In addition, by having several inputs to the cryptographic module, instead of merely one, the cryptographic function may be made to be dependent on a sequencing of data between the inputs. In other words, the cryptographic module may require simultaneous inputs on two or more sensors. Cryptographic module may also require a sequence of data inputs. By hiding cryptographic inputs through non-contact means, requiring various non-contact input orientations and data sequencing and by using different sensors, security within cryptographic modules can be greatly enhanced. <IMAGE>
Patent IL-143134-A0 (IL)
Title: Security room for information technology facilities
IPC: G06F1/16
Filed: 1999-04-20
Abstract: A security room for information technology facilities, which exhibits fireproof side walls having a sealing door, a floor and a ceiling. This invention provides a security room designed in a simple way and readily adapted to different spatial configurations, while exhibiting a good fireproofing capacity. The side walls, the floor surrounded by the side walls, and the ceiling are assembled in a modular manner from individual members which are laid side-by-side and connected together by fireproofing materials.
Patent IL-147024-A0 (IL)
Title: Fire inhibiting flat element comprising at least two transparent fire-resisting glass plates
IPC: E06B3/64
Filed: 2000-07-03
Abstract: Fire-retardant sheet element can be composed of several fire protection glass plates (2, 3). Lateral edges (9, 10) of adjacent glass plates (2, 3) therein abut one another. Into the interspace (26) between lateral edges (9, 10) a sealing configuration (7) is installed. This comprises an addition element (22) and elastic sealing elements (23, 24). The glass plates (2, 3) comprise several glass panes (16) and interspaced fire protection layers (18). These fire protection layers (18) do not extend up to the edges (9, 10) and are sealed in the regions of the lateral edges with a barrier material (20). No additional frame elements for covering the interspace (26) and for sealing are necessary.
Patent IL-191131-A0 (IL)
Title: Drospirenone for hormone replacement therapy
IPC: A61K9/14
Filed: 2008-04-29
Abstract: The present invention relates to compositions comprising drospirenone together with a pharmaceutically acceptable carrier of excipient, wherein said composition does not contain an estrogen. In one embodiment drospirenone is in micronized form. In another embodiment drospirenone is in a form having a surface area of more than 10,000 cm 2 /g. In a further embodiment drospirenone is in a form having rapid dissolution such that at least 70% of said drospirenone is dissolved within 30 minutes when the composition is subjected to dissolution testing in 900 ml of water at 37 °C using USP XXIII Paddle Method II operated at a stirring rate of 50 rpm. In a still further embodiment the composition comprises inert carrier particles containing drospirenone on their surface.
Patent IL-200408-A0 (IL)
Title: Array for influencing the radiation characteristics of a reflector antenna, particularly a centrally focused reflector antenna
Filed: 2009-08-13
Abstract: The invention relates to an array for influencing the radiation characteristics of a reflector antenna, particularly a centrally focused reflector antenna (1) consisting of a hollow conductor (3) with a horn (4) and a sub-reflector component (2), whereby the assembly consists of at least two immoveable triggerable radiator elements (5; 6; 7; 8), which influence the beam path between the reflector (9) and sub-reflector (10) in the operating state. The array has the advantage of providing a small-size technical solution which requires minimal mechanical and electrical efforts for reflector antennas and allows the antenna to track a satellite with high accuracy. Within certain limits, signal reception and the antenna diagram can be controlled such that reception and transmission can be simultaneous. The beam of diagram can be controlled in real time. Another advantage is that the hemisphere can be reproduced in full, i.e. at an angle of elevation ranging from 0° to 180° and an azimuthal angle ranging from 0° to 360°. The array can be used in previously known reflector antennas, is tolerant towards the ambient temperature, humidity, and vibrations and is inexpensive to produce since it requires a small number of control elements.
Patent IL-218718-A0 (IL)
Title: Coarse pigment addition and high solids slurries for higher coating colour concentrations
Filed: 2012-03-19
Abstract: The present invention relates to an aqueous slurry comprising natural ground calcium carbonate which has a percentage P 5  by weight of particles having a diameter of less than 5.0 µm of from 98.5 % to 90 %, a percentage P 2  by weight of particles having a diameter of less than 2.0 µm of from 96 % to 80%, wherein the ratio of P 2 /P 5  is from 0.98 to 0.85, and wherein the slurry has a solids content of more than 78 wt%.
Patent RO-127221-A0 (RO)
Title: Process for improving the thermal comfort and reducing the noxious substances at the ground level
Inventor: ŢURCAN VASILE
IPC: F03D11/00
Filed: 2011-06-16
Abstract: The invention relates to a process for improving the thermal comfort and reducing the noxious substances at the ground level, with or without catching the wind energy, which may be converted into electric power. According to the invention, the process consists in mounting a stack on the ground, which forces the hot air from the ground level to circulate ascendently by the entrainment of the air with a fan.
Patent RO-132473-A0 (RO)
Title: Shampoo composition used for treating dry lesions in canine demodicose
Inventor: MEDERLE NARCISA
IPC: A61P17/02
Filed: 2017-12-07
Abstract: The invention relates to a shampoo composition used for treating canine demodicosis dry lesions, produced on the dog's skin by Demodex spp. mites. According to the invention, the composition comprises 20% shampoo base consisting of anionic and non-ionic surface-active agents such as sodium or ammonium lauryl ether sulphate, cocamide diethanolamine, cocamide propyl betaine, sodium lauroyl sarcosinate, 1...5% collagen hydrolysate, 20% a mixture of hydro-glycerol-alcoholic extracts of black currant buds, walnut tree buds, dog rose buds, cedar sprouts, rye radices in a ratio of 1:5 for each of the five ingredients, 1...5% NaCl as a thickening agent and, for the remainder, distilled water, the parts being expressed by weight.
Patent RO-133545-A0 (RO)
Title: Topical product comprising natural active principles used in chronic wounds treatment and industrial process for preparing the same
Inventor: ANDRIEŞ CLAUDIA
IPC: A61K31/198
Filed: 2018-09-19
Abstract: The invention relates to a topical product used in chronic wounds treatment and to a process for preparing the same. According to the invention, the product is a hydrogel consisting of 0.1...5% sodium hyaluronate, L-arginine and chitosan, respectively 0.5...10% bentonite, 5...50% glycerol, 0.02...6% lactic acid, up to 5% gel-forming substance, preferably hydroxyethylcellulose, 20...85% purified water, up to 5% betulin, and 15% pharmaceutically acceptable carrier, preferably propylene glycol. The claimed process consists in preparing the chitosan gel by hydration at 45°C and solubilization by acidulation with lactic acid, suspending the sodium hyaluronate in glycerol, suspending the bentonite, mixing the components and adding the active ingredients with homogenization at the room temperature, to result in a hydrogel having antioxidant and antimicrobial activity for a wide range of specific microorganisms.
Patent ZM-9282-A1 (ZM)
Title: Non-electric blasting assembly
IPC: F42D1/04
Filed: 1982-12-21
Abstract: A detonator closed at one end by a primer shell (1) whose integrally closed end (1a) has a percussion-sensitive primer charge (3) supported adjacent its inside surface, and its outside surface (2a) disposed across the end of the detonator shell, is actuated by the detonation of one or two lengths of low-energy detonating cord (LEDC) adjacent the primer shell's outside end surface, a single length (7) of LEDC being arrayed in segments (7c, 7d) thereof, or two lengths arrayed in a manner such that a segment (7c, 7d) from each length, is anchored in place in side-by-side relationship adjacent said surface. This cord array assures reliable ignition of a center- or rim-fired percussion primer by means of the side-output of LEDC even with explosive core loadings at the low end of the LEDC loading range. A preferred detonator has a sleeve (14) having a loop-like projection (16) most preferably M-shaped, diametrically disposed beyond the primer shell end through which a looped length of LEDC can be threaded in various ways to hold the pair of segments adjacent the primer shell.
Patent ZW-9680-A1 (ZW)
Title: 2-aminoalkyl-5-pyridinols process for their manufacture pharmaceutical preparations containing these compounds and their therapeutic application
Inventor: MIZZONI RENAT HERBERT
IPC: C07D213/65
Filed: 1980-04-30
Abstract: There is described a process for preparing an enamine of formula (IX):   <IMAGE> where R<2> is a carboxylic acid protecting group and R<3> is the residue of a carboxylic acid derived acyl group and where R<5> and R<6> are the same or different C1-4 alkyl or C1-10 aralkyl groups; or taken together with the adjacent nitrogen atom form a heterocyclic ring containing from 4 to 8 carbon atoms and optionally a further heteroatom selected from oxygen and nitrogen; by reacting a compound of formula (XII):   <IMAGE> with an amine of formula HNR<5>R<6>, the reactant of formula (XII) being prepared by reaction of an appropriate enol derivative with a phosphorus reagent. The enamines of formula (IX) are useful in the preparation of 3- hydroxycephalosporins. The compounds of formula (XII) are novel.
Patent CU-21698-A1 (CU)
Title: Sistema automatico para la determinacion y control de sacarosa en aguas de condensados
Inventor: RODRIGUEZ BAEZ GUIDO CLEMENTE
IPC: G01N15/06
Filed: 1984-07-23
Abstract: La presente invención se relaciona con la industria azucarera, en especial con la determinación de sacarosa en los condensados producidos en el sistema de evaporación de las fábricas de azúcar. Esta consiste en un equipo que realiza dicha determinación y que está compuesto por tomamuestra a la línea, un condensador y fotocolorímetro acoplados a un sistema electrónico con conversor I/V, amplificador de senal, conversor analógico-digital, display electrónico, fuente de corriente directa, set point, comparador analógico de senales, amplificador de potencia, bloque de control y electroválvulas que desvían o no el flujo de condensados en función de la contaminación, así como un sistema compuesto por recipiente a nivel constante y frasco de Mariotte que controlan la relación muestra-reactivo respectivamente que entra al reactor, un reactor sohxlet donde tiene lugar la reaccion colorimétrica y una celda sohxlet que forma parte del sistema de medición y control.
Patent MA-37834-A1 (MA)
Title: Analogues de pyridazine 1,4-disubstituée et procédés de traitement de troubles liés à une déficience en smn
Inventor: CHEUNG ATWOOD
IPC: C07D487/10
Filed: 2013-08-13
Abstract: La présente invention concerne un composé de formule (i) ou un sel pharmaceutiquement acceptable de celui-ci ; un procédé de fabrication desdits composés, et leurs utilisations thérapeutiques. La présente invention concerne également une combinaison d'agents pharmacologiquement actifs et une composition pharmaceutique.
Patent MA-39347-A1 (MA)
Title: Protéines de fusion d'uti
Inventor: CHAMBERLAIN AARON
IPC: C07K14/81
Filed: 2015-02-23
Abstract: La présente invention concerne des protéines de fusion d'uti, des séquences d'adn pour produire ces protéines, et des compositions pharmaceutiques et des méthodes d'utilisation correspondantes.