baber/WOPTO huggingface dataset:
Patent DK-1210327-T3 (DK)
Inventor: STEINMEYER ANDREAS
IPC: C07D333/22
Filed: 2000-07-24
Granted: 2006-04-03
Abstract: Vitamin D derivatives (I), having a cyclic substituent in the side-chain, are new. Also new are perhydroindane derivative intermediates (A) ands (B).  Vitamin D derivatives of formula (I), including all possible epimers, diastereomers and their mixtures, are new. Y1, Y2  =  H or -C(O)R5;  Y3 (in alpha- or beta-configuration)  =  H, OH, halo, OC(O)R5 or OR5;  R5  =  5-12C aromatic residue; or 1-12C optionally unsaturated alkyl (optionally interrupted by 1 or 2 O, 1 or 2 S and/or 1 or 2 NH; and optionally substituted by 1 or 2 OH, 1 or 2 NH2, 1 or 2 SH, 1 or 2 COOH and/or 1 or 2 COOH);  R1, R2  =  H or together form exocyclic =CH2;  R3, R4  =  H, F, Cl, Br or 1-4C alkyl;  or CR3R4  =  -C(=CH2)- or a 3-7 membered saturated or unsaturated carbocyclic ring;  Q  =  1-5C n-alkylene;  X1, X2  =  H, OH, OC(O)R5, F, Cl or Br (but not both OH or both -OC(O)R5);  or CX1X2  =  C=O;  Z'  =  carbocyclic or heterocyclic (including aromatic or heteroaromatic) ring system comprising a 5- or 6-membered ring optionally fused with a 6-membered ring (optionally substituted by one or more of each of halo, OH, COOR6 or 1-5C alkyl (itself optionally substituted by one or more of halo, 1-6C alkoxy and/or COOR6));  R6  =  1-6C alkyl, benzyl or phenyl. Independent claims are included for: (1) new perhydroindane derivative intermediates of formulae (A) and (B); (2) preparation of perhydroindane derivative intermediates of formula (XIIIa) by: (a) reacting a perhydroindane derivative of formula (A; T replaced by L) with protected, deprotonated propargyl alcohol to give (A; T = -CC-CH2OY5), (b) hydrogenating and deprotecting to give (A; T = -(CH2)3OH), (c) oxidizing to give (A; T = -CH2CH2CHO) and (d) reacting with a nucleophile Nu, cleaving Y4 and oxidizing the free OH group; and (3) preparation of vitamin D compounds of formula (IIa) by: (a) reacting a ketone of formula (XIIIb) with a trimethylsilyl acetoacetate ester in presence of a base or with a Wittig reagent in an aprotic solvent to give (B; U = COOR6), (b) reducing to give (B; U = CH2OH), (c) converting into (B; U replaced by L), (d) converting into the Wittig reagent (B; U = CH2P(O)(G)2) and (e) reacting with a ketone of formula (XXXIII) and optionally deprotecting the product.  T  =  -CC-CH2OY5, -(CH2)3OH or -CH2CH2CHO;  Y4  =  trialkylsilyl, mixed aryl-alkyl substituted silyl, tetrahydropyranyl or tetrahydrofuranyl protective group;  Y5  =  tetrahydropyranyl or benzyl;  E  =  side-chain, in which any keto and/or hydroxy groups are protected;  U  =  COOR6, CH2OH or CH2P(O)(G)2;  Y6  =  1-6C alkyl, benzyl or phenyl;  G  =  1-10C alkyl, 1-10C alkoxy, Ph or OPh;  L  =  leaving group;  Nu  =  nucleophile;  R7, R8  =  H or Me; or together form exocyclic =CH2 or a cyclopropane ring;  Y6  =  F, (CH2)nOH or (CH2)nOCOR5;  n  =  0-4;  Y'1  =  hydroxy-protecting group;  Y'3  =  H, halo or as Y'1.
Patent DK-1164145-T3 (DK)
Inventor: KENNEDY THOMAS P
IPC: C08B37/00
Filed: 1993-07-23
Granted: 2008-04-14
Abstract: A method and medicament for the inhibition of neutrophil elastase and cathepsin G in mammals comprising administering a treatment effective amount of 2-O-desulfated heparin to a mammal in need thereof. The medicament preferably is administered by aerosolization or by intravenous (IV) injection. In specific embodiments of the invention, the ratio of 2-O-desulfated heparin to elastase is greater than about 0.2 and less than about 2.0, or the ratio of 2-O-desulfated heparin to cathepsin G is greater than about 0.4 and less than about 2.0. Preferably, the 2-0 desulfated heparin medicament includes a physiologically acceptable carrier which may be selected from the group consisting of physiologically buffered saline, normal saline, and distilled water.
Patent DK-1306014-T3 (DK)
Inventor: BESNER HANS DR-ING
IPC: A23J1/20
Filed: 2001-10-23
Granted: 2004-03-22
Abstract: Production of whey protein aggregates from sour whey or a sour whey concentrate or protein isolate comprises heating the starting material at 90-120 degrees C under non-shearing conditions for up to 60 seconds.
Patent DK-1296658-T3 (DK)
Inventor: ROVERSI FRANCESCO
IPC: A61K47/34
Filed: 2001-01-26
Granted: 2007-08-06
Abstract: A starch with a high content in amylose, obtained through a process comprising acetylation and pre-gellation, can provide useful coatings in food, drug, cosmetic and dietetic fields, both for humans and animals, and also in agriculture.
Patent DK-1279259-T3 (DK)
Inventor: ERIKSSON JONAS
IPC: H04L12/56
Filed: 2001-04-12
Granted: 2007-11-26
Abstract: Method and device for measuring and processing of information in a communication system which includes a packet switching communication network, in which communication network a base station is arranged to cover cell, and a mobile station which can communicate wirelessly with said base station within said cell for transmission of data packets in a temporary block flow. The method is characterized in the steps to establish a first temporary block flow, and at that start measuring of a first parameter when the transmission of data packets is started; finish the mesuring of the first parameter when the first block flow is finished/stopped, and at that start measuring of a second parameter; establish a second temporary block flow, and at that finish the measuring of the second parameter; store the measuring values of the first and  second parameter; calculate a ratio depending on said measuring values.
Patent DK-1303580-T3 (DK)
Inventor: HJALTASON BALDUR
IPC: C07D319/24
Filed: 2001-07-19
Granted: 2006-09-25
Abstract: A method is provided for the removal of polychlorinated contaminants including polychlorinated dioxins, furans, byphenyls, and polycyclic aromatic hydrocarbons from marine oils by a process that minimizes processing of the oil, and the degradation of polyunsaturated fatty acids. Also provided are marine oils such as cod liver oil obtained by the method of the invention than can be used otherwise unrefined as a source of economical, contaminant-reduced bulk marine oil.
Patent DK-1423260-T3 (DK)
Inventor: CHRISTIAENS DIRK
IPC: B29B11/12
Filed: 2001-09-05
Granted: 2007-03-19
Abstract: The rotary tablet press comprises a housing, in which a compression unit (14) is detachably mounted. The compression unit (14) comprises a die table (15) with punches (17, 18), a feeding device for the supply of material to be compressed into the dies (16), and a tablet discharge device for removal of compressed material in the form of tablets. The compression unit (14) encloses each die opening and its corresponding first punch end (21, 22) in a chamber, the feeding device and the tablet discharge device are enclosed, the feeding device communicates with an inlet for detachable connection with an external supply channel, and the tablet discharge device communicates with an outlet.
Patent DK-1320375-T3 (DK)
Inventor: BUDDINGTON RANDAL K
IPC: A23L1/308
Filed: 2001-09-27
Granted: 2006-05-22
Abstract: The use of a dietary fiber or a mixture of dietary fibers for the manufacture of a composition, being a pharmaceutical composition or a functional food or a functional feed, for the prevention, the inhibition and/or the treatment of systemic infections in humans and in vertebrates caused by pathogenic bacteria is disclosed. A method for the prevention, the inhibition and/or the treatment of systemic infections in humans and in vertebrates caused by pathogenic bacteria, comprising administration to said beings, orally, through tube feeding or rectally, a composition containing an effective amount of a dietary fiber or mixture of dietary fibers is also disclosed. The dietary fiber is preferably a fructan, typically inulin and/or oligofructose, most preferably chicory inulin with an average degree of polymerization <O OSTYLE="SINGLE">(DP) of at least 20.
Patent DK-1430034-T3 (DK)
Inventor: SIMIG GYULA
IPC: A61K31/50
Filed: 2002-09-26
Granted: 2005-05-30
Abstract: The invention relates to substituted alkylaminopyridazinone derivatives of the general Formula (I), (wherein R<SUB>1 </SUB>is hydrogen or alkyl having 1-4 carbon atoms; one of X and Y stands for hydrogen or halogen and the other represents a group of the general Formula (II), R<SUB>2 </SUB>is hydrogen or alkyl having 1-4 carbon atoms; n is 1, 2 or 3; R<SUB>3 </SUB>stands for hydrogen, alkyl having 1-4 carbon atoms or aryl-(C<SUB>1-4 </SUB>alkyl); Z stands for oxygen; or R<SUB>3 </SUB>and Z together with the groups placed between them form a piperazine ring; and R<SUB>4 </SUB>stands for hydrogen, halogen, trifluoromethyl or alkoxy having 1-4 carbon atoms) and pharmaceutically acceptable acid addition salts thereof. The invention compounds are useful in the treatment of anxiolytic conditions and cognitive disorders.
Patent DK-1365577-T3 (DK)
Inventor: REICHENBACH JUERGEN
IPC: H04N1/41
Filed: 2003-04-17
Granted: 2006-06-12
Abstract: Reflected light (26) from an object (18) with codes (20,22), is received line by line by a light receptor (24), to obtain a picture. The obtained picture is compressed by a compression unit (34) using picture compression algorithm, while receiving the picture.  An Independent claim is also included for opto-electronic sensor.
Patent DK-1509464-T3 (DK)
Inventor: FRENCH GARY STUART
IPC: B65D75/34
Filed: 2003-05-08
Granted: 2011-10-03
Abstract: The child-resistant blister pack for unit dosage forms has a blister film sheet with depressions therein, unit dosage forms within the depressions and a lidding sheet which overlies the depressions and which is secured to the film sheet so as to seal the unit dosage forms within the depressions. A network of lines of weakness in the pack define a plurality of dosage units. Each dosage unit includes one of said dosage forms and a peel region where part of the lidding sheet is not secured to the blister film sheet. Each peel region is disposed adjacent a respective one of the lines of weakness. The lines of weakness include (a) a first line of weakness extending from a first access point so that, when the first access point is exposed, the blister film sheet and the lidding sheet can be torn along the first line of weakness to expose a second access point and to enable access to the peel region of the first dosage unit; (b) a second line of weakness extending from the second access point so that, when the second access point is exposed, the blister film sheet and the lidding sheet can be torn along the second line of weakness to expose a third access point and enable access to the peel region of the second dosage unit; and (c) a third line of weakness which is spaced from the first line of weakness and which extends from the third access point so that, when the third access point is exposed, the blister film sheet and the lidding sheet can be torn along the third line of weakness to enable access to the peel region of a third dosage unit.
Patent DK-1512016-T3 (DK)
Inventor: MILLAR ROBERT PETER MRC HUMAN
IPC: A61P15/00
Filed: 2003-07-22
Granted: 2006-07-03
Abstract: A method for identifying a test compound that has an anti-tumoral effect whilst not significantly activating unrelated transduction signals, the method comprising the steps of: (a) selecting at least one test compound; (b) assaying the compound for anti-tumoral effect; (c) selecting at least one distinct intracellular event which is modulated, at least partially, by the GnRH receptor; (d) testing for the ability of said test compound not to modulate the selected intracellular event; and (e) selecting the test compound which selectively demonstrates an anti-tumoral effect and does not modulate said other selected intracellular event. A method according to any one of the preceding claims, the method comprising: (a) selecting at least one test compound; (b) determining whether the test compound activates signalling via Galphai; (d) testing for the ability of said test compound not to modulate signalling via Galphaq; and (e) selecting the test compound which selectively activates signalling via Galphai and does not modulate signalling via Galphaq. Compounds selected by the methods, including Ac-D-Nal(2)-D-4-ClPhe-D-Pal-Ser-1-MePal-D-IsopropylLys-Leu-IsopropylLys-Pro-D-AlaNH<SUB>2</SUB>, are useful in combating cancer and reproductive tissue hyperplasias.
Patent DK-1562611-T3 (DK)
Inventor: FLEMING IAN
IPC: A61K31/341
Filed: 2003-11-19
Granted: 2006-12-04
Abstract: A compound of formula (I) wherein one of X and Y is silicon, and the other is carbon or silicon; Z is oxygen, sulphur or -N(R)-, wherein R is hydrogen or alkyl; R<SUP>1 </SUP>is hydrogen, halogen, alkyl, alkenyl, alkynyl, alkoxy or cycloalkyl; and R<SUP>2 </SUP>is alkyl, alkenyl, alkynyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, -alkyl-cycloalkyl, -alkyl-heterocycloalkyl, -alkyl-aryl or -alkyl-heteroaryl; or a pharmaceutically acceptable salt thereof. The compounds are used in the manufacture of a medicament for the treatment or prevention of a disease or condition associated with GnRH (gonadotropin-releasing hormone), e.g. for the treatment or prevention of progression of cancer (e.g. leukaemia therapy), of a fertility disorder, of HIV infection or AIDS, of Alzheimer's disease of fibrosis, of endometriosis, of uterine fibroids or of uterine leiomyom
Patent DK-1694626-T3 (DK)
Inventor: MEERDINK JOHANNES
IPC: C07C55/28
Filed: 2003-12-10
Granted: 2008-03-03
Abstract: The present case relates to a process for the purification of lactide from a crude lactide vapor product stream which process comprises a rectification/condensation step leading to a lactide-enriched condensate.
Patent DK-1534819-T3 (DK)
Inventor: PHELPS CAROL J
IPC: C12N5/06
Filed: 2003-08-21
Granted: 2010-04-19
Abstract: The present invention is a porcine animal, tissue, organ, cells and cell lines, which lack any expression of functional alpha 1,3 galactosyltransferase (alpha 1,3GT). These animals, tissues, organs and cells can be used in xenotransplantation and for other medical purposes.
Patent DK-1576929-T3 (DK)
Inventor: AMPLATZ KURT
IPC: A61B17/00
Filed: 2005-03-11
Granted: 2008-09-29
Abstract: A collapsible medical device and associated methods of occluding an abnormal opening in, for example, a body organ, wherein the medical device is shaped from plural layers of a heat-treatable metal fabric. Each of the fabric layers is formed from a plurality of metal strands and the assembly is heat-treated within a mold in order to substantially set a desired shape of the device. By incorporating plural layers in the thus-formed medical device, the ability of the device to rapidly occlude an abnormal opening in a body organ is significantly improved.
Patent DK-1588768-T3 (DK)
Inventor: NIELSEN STEFFEN
IPC: B01D29/09
Filed: 2005-04-19
Granted: 2010-03-08
Abstract: When, according to the method of the invention, an automatic cleaning system is constructed such that used cooling/lubricating ag
Patent DK-1706306-T3 (DK)
Inventor: KOFOED HENRIK
IPC: G05G9/047
Filed: 2005-01-11
Granted: 2012-01-30
Abstract: Driving and steering means of a wheeled, power driven vehicle, such as a power driven hospital bed, is actuated by an actuating device ( 30 ). This actuating device comprises a base member ( 31 ) and an actuating member ( 32 ) having gripping means, such as a pair of spaced handles ( 33 ), and being supported by the base member so as to be displaceable thereon along a plane. A first force transducer ( 34 ) is arranged to receive a force component manually applied to the actuating member in a predetermined first direction only, along said plane, and a second force transducer ( 38 ) is arranged to receive a force component manually applied to the actuating member in a predetermined second direction only, transversely to the first direction along said plane. Each of these force transducers is adapted to generate an output signal to the driving and steering means responsive to the strength of the force component received. Preferably, the first and second directions extend at mutual right angles, and one of the directions extends in the normal direction of travel of the vehicle.
Patent DK-1718829-T3 (DK)
Inventor: RAUHALA TIMO
IPC: E05C/
Filed: 2005-01-24
Granted: 2009-08-10
Abstract: The present invention relates to an arrangement (1) for a door or some other covering element (2) which exhibits an espagnolette (3) with a straight end piston (4). In accordance with the invention, a brake (5) is connected in such a way as to permit operation through the displacement effect of the end piston (4). A spindle (6), which exhibits a central bearing (7) and an eccentrically situated movement transmission pin (8), is supported in such way that it is accomodated in an attachement (9) for a brake transmission housing (10) connected to an edge rail (11) for the door (2), etc., and with the aforementioned pin (8) accomodated in a curved recess (12) in the aforementioned brake transmission housing (10). The invention permits the combination of an espagnolette (3) which exhibits a straight end piston (4) with a brake (5), which enables it to be used with a Euronot.
Patent DK-2007658-T3 (DK)
Inventor: BRAUN MATHIAS
IPC: B65G1/04
Filed: 2006-05-06
Granted: 2010-02-01
Abstract: In a storage lift comprising a plurality of shelf columns (3a, 3b) which lie next to one another and opposite one another on both sides of a conveying shaft (15), a horizontally displaceable support frame (18) for a conveyor (26) which is movable upwards and downwards is guided in the conveying shaft (15) on two guide rails (16, 17), of which one is connected fixedly to the base (23) of the conveying shaft (15) and one is arranged in the upper region thereof.
Patent DK-1969696-T3 (DK)
Inventor: SAINT-MICHEL JACQUES
IPC: H02K1/27
Filed: 2006-12-26
Granted: 2011-10-24
Abstract: The machine has a rotor (20) defining an air gap (40) with a stator (10), and comprising permanent magnets (21, 23, 25, 27) and pole pieces between the magnets. One pole piece (22) is associated with the permanent magnets to concentrate magnetic flux of the magnets, where the magnets define three different magnetization directions. The resultant flux in the polar pieces is in a direction of the stator that is non-coplanar with the magnetization directions.
Patent DK-2278686-T3 (DK)
Inventor: HJORT THOMAS ENNE
IPC: H01H47/32
Filed: 2005-08-30
Granted: 2012-07-16
Abstract: An uninterruptible power supply for providing power to a load, including a bypass input selectively coupled to the output to provide output power from a bypass power source, the uninterruptible power supply being arranged in a bypass mode of operation to control an inverter circuit to convert AC power from the bypass power source at the output of the inverter circuit to DC power at the input of the inverter circuit, further comprising a battery charger coupled to the input of the inverter circuit to receive DC power and provide power to charge the back-up power source in the bypass mode of operation and a power supply separate from the battery charger and coupled to the input of the inverter circuit to receive DC power and arranged to provide DC power to components of the uninterruptible power supply in the bypass mode of operation.
Patent DK-2909122-T3 (DK)
Inventor: ANNEN MIRCO
IPC: B66B5/06
Filed: 2013-10-18
Granted: 2018-08-20
Abstract: A method and an equipment for monitoring the movement of an elevator car detect an acceleration of the elevator car and a travel speed or a travel distance of the elevator car and an integrated travel speed is calculated from the detected acceleration. In that case, the detected travel speed or the travel speed derived from the detected travel distance is used as a start variable of an integration cycle. In addition, the integrated travel speed is compared with at least one predetermined limit speed and a safety measure is triggered if exceeding of the predetermined limit speed is established.
Patent DK-2824933-T3 (DK)
Inventor: THANG TRUONG CONG
IPC: H04N21/845
Filed: 2011-09-01
Granted: 2018-08-27
Abstract: A method and apparatus for an adaptive Hypertext Transfer Protocol (HTTP) streaming service using metadata of content are provided. The metadata of the content may be efficiently divided for a purpose of use of a terminal based on general media information or specific media information, and may be transmitted to the terminal. A group may include one or more representations of content. The metadata may include a group element, and the group element may provide a summary of attributes of one or more representations included in the group.
Patent DK-0394002-T3 (DK)
Inventor: SENDELWECK GENE KARL
IPC: H04N9/64
Filed: 1990-04-18
Granted: 1995-12-18
Abstract: An auxiliary video input terminal (S-terminal) couples luminance amd chrominance input signals to respective inputs of peaking circuits (52, 58) in the display processor (40) of a receiver. The chrominance input signal is subjected to pre-distortion (de-peaking) (80) to correct for sideband amplitude distortion in the chrominance peaking filter of the receiver thereby preventing color distortion in displayed images. The luminance signal is subjected to additional peaking (52) at a frequency greater than the characteristic peaking frequency of the luminance peaking filter thereby enhancing the sharpness of wideband luminance input signals displayed by the receiver. <IMAGE>
Patent DK-0458207-T3 (DK)
Inventor: TANAKA HIROKAZU
IPC: C07D403/10
Filed: 1991-05-17
Granted: 1997-04-21
Abstract: The present invention relates to novel indole derivatives of the formula : <CHEM>  wherein   R<1> is    carboxy or protected carboxy, R<2> is    hydrogen, lower alkyl or halogen, R<3> is    aryl or ar(lower)alkyl, each of which may have suitable substituent(s), or a group of the formula : <CHEM>   A is    lower alkylene which may be substituted by oxo or lower alkenylene, Q is    carbonyl or lower alkylene, X is <CHEM>  or <CHEM>  in which R<4> is    hydrogen or lower alkyl, and R<5> is    hydrogen, lower alkyl or Y-Z-R<3>, Y is    bond or lower alkylene, Z is    lower alkylene, -O- or <CHEM>  in which R<6> is    hydrogen, lower alkyl, ar(lower)alkyl which may have suitable substituent(s) or amino protective group, and pharmaceutically acceptable salts thereof, which have pharmacological activities such as inhibitory activity on testosteron 5 alpha -reductase and the like, to process for preparation thereof, to a pharmaceutical composition comprising the same and to a use of the same for manufacturing a medicament.
Patent DK-0468484-T3 (DK)
Inventor: GELLERT JOBST ULRICH
IPC: B29C45/73
Filed: 1991-07-24
Granted: 1995-09-11
Abstract: An injection molding integral cooled socket holder (10) to be seated in a well (64) in a cavity plate (12) to receive an elongated heated nozzle (14). A central tube portion (88) extends between a rear collar portion (84) and a forward socket portion (86) to form an elongated socket to receive the nozzle. The tube portion (88) has small diameter inlet and outlet tubes (90,92) received in longitudinal grooves (94,96) which carry a flow of cooling water which is received at the rear collar portion (84) to the forward socket portion (86). The water flows around a circular conduit (112) in the forward socket portion (86) to provide cooling adjacent the gate (32). The components of the socket holder (10) are integrally brazed together in a vacuum furnace. Socket holders are made with various preselected lengths to match different length nozzles (14) by cutting the central tube (88) portion including the inlet and outlet tubes (90,92) to different standard lengths. <IMAGE>
Patent DK-0502524-T3 (DK)
Inventor: KIENER ANDREAS DR
IPC: C12R1/19
Filed: 1992-03-05
Granted: 1996-06-03
Abstract: A microbiological process for the terminal hydroxylation of ethyl groups on aromatic 5- or 6-membered heterocycles is described. The hydroxylation is carried out with microorganisms which   a) contain the genes of a Pseudomonas OCT plasmid which form an active alkane monooxygenase and b) form no active chromosomal- or plasmid-encoded alcohol dehydrogenase. i