baber/WOPTO huggingface dataset:
Patent WO-2021154777-A1 (WO)
Title: Methods for authenticating an item
Inventor: IYER PRADEEP S
IPC: G06K19/08
Filed: 2021-01-27
Abstract: Methods and systems including one or more entropically configured distinct physical features (an "identropy") that serve as unique identifiers for a physical item, such as a product or device, particularly products and/or devices in commerce, documents, packaging, etc. are described herein. The identropy makes it possible to uniquely distinguish one item from the other. In one embodiment, the identropy needs to be converted into a digital entity which can be done through a challenge - response interaction, in which a physical challenge acts upon the identropy, and in which the identropy as a reaction to the challenge will provide a physical response. In some embodiments, the response(s) described above is encrypted. In some embodiments, the resulting decrypted and optionally decompressed code can be compared to the digital response that was retrieved upon the challenge by the authentication device to estimate a trust score, such as a trust quotient.
Patent WO-2021159093-A1 (WO)
Title: Inhibition of beta-arrestin oligomerization in tauopathy
Inventor: WOO JUNG A
IPC: A61P35/00
Filed: 2021-02-08
Abstract: As disclosed herein, β-arrestin1 and β-arrestin2 levels are highly elevated in brains of FTLD-tau patients suggesting that both β-arrestin1 and β-arrestin2 are elevated in the brains of patients with AD and FLTD. The current work also shows that when β-arrestin2 is overexpressed, tau levels become elevated. The data indicate that β-arrestin2 reduces tau clearance by impairing p62-mediated autophagy, a role carried out by the oligomerized form of β-arrestin2. Therefore, disclosed herein are β-arrestin oligomerization inhibitors that can be used to prevent β-arrestin oligomerization and therefore the accumulation of tau in cells, i.e. tauopathy. Also disclosed are methods of treating a tauopathy in a subject that involve administering to the subject a therapeutically effective amount of a β-arrestin oligomerization inhibitor disclosed herein.
Patent WO-2021173356-A1 (WO)
Inventor: DIXIT SUNIL
IPC: G05B23/02
Filed: 2021-02-11
Abstract: An exemplary method implemented by a computing system determines a prediction of degradation of components in a complex vehicle to enable cost effective maintenance and enhance vehicle operational availability (vehicle readiness for missions) based on currently measured performance-based parameters associated with the respective components. Residues from models of the components reflect differences between performance as determined by the models of the components and currently measured actual performance parameters. The residues are used determine a level of degradation and a rate of change of degradation for the respective components. The remaining useful life (RUL) of the respective components is the projected/predicted time of remaining acceptable performance of the respective component, and is based on the current degradation level, the rate of change of degradation, and a stored threshold level of degradation that is a maximum amount of degradation that is acceptable.
Patent WO-2021163466-A1 (WO)
Inventor: LIU YANG
IPC: A61P35/02
Filed: 2021-02-12
Abstract: La présente invention concerne le traitement de l'AML mutée par TP53 au moyen d'un facteur inductible par l'hypoxie (inhibiteur de HIF). L'invention concerne en outre une nouvelle formulation d'inhibiteur de HIF ayant une demi-vie plus longue et un effet thérapeutique significativement amélioré pour l'AML mutée par TP53.
Patent WO-2021173987-A1 (WO)
Inventor: SEN CHANDAN K
IPC: A61K9/51
Filed: 2021-02-26
Abstract: Compositions and methods are provided for modifying the contents of exosomes released by target cells. In one embodiment cell targeted nanoparticles are used to deliver interference RNAs to the target cells which alter the packaging of exosomes released by the target cells.
Patent WO-2021178597-A1 (WO)
Inventor: YANG JUNHAO
IPC: A61K47/65
Filed: 2021-03-03
Abstract: Provided herein are antibodies comprising acceptor glutamine sequences at site-specific positions, compositions comprising the antibodies, conjugates of the antibodies, methods of their production, and methods of their use. The antibodies are useful for methods of treatment and prevention, methods of detection and methods of diagnosis.
Patent WO-2021216226-A1 (WO)
Inventor: ZIELINSKI CHRISTINE
IPC: C10G33/00
Filed: 2021-03-17
Abstract: In an embodiment is provided a process to re-refine used oil that includes introducing a used oil and a solvent to a separation unit under separation conditions selected to produce a purified oil product, the separation unit comprising a porous membrane, a semiporous membrane, or both; and separating the used oil to obtain an effluent comprising a purified oil product. In another embodiment is provided an apparatus for re-refining used oil that includes a separation unit comprising a porous or semiporous membrane; a used oil feed coupled to an inlet of the separation unit; and an inlet of a diffusate collection unit coupled to an outlet of the separation unit. In another embodiment is provided a composition generated from a membrane separation process that includes a base oil, the composition having a soot content of about 0.05% or less.
Patent WO-2021195358-A1 (WO)
Inventor: SCHACHT DEREK
IPC: H02J4/00
Filed: 2021-03-25
Abstract: A method for monitoring power consumption of an appliance within a space is provided. The method includes obtaining a first set of data indicative of power consumption of the appliance during an interval of time and determining a profile indicative of power consumption of the appliance based, at least in part, on the first set of data. The method includes obtaining a second set of data indicative of power consumption of the appliance subsequent to obtaining the first set of data. The method includes determining whether power consumption of the appliance deviates from the profile based, at least in part, on the second set of data. Furthermore, in response to determining power consumption of the appliance deviates from the profile, the method includes providing a notification indicative of power consumption of the appliance deviating from the profile.
Patent WO-2021202678-A1 (WO)
Title: Masked il-12 cytokines and their cleavage products
Inventor: ROZENFELD RAPHAEL
IPC: C07K14/54
Filed: 2021-03-31
Abstract: The present invention relates to masked IL-12 cytokines, comprising an IL-12 cytokine or functional fragment thereof, a masking moiety and a proteolytically cleavable linker. The masking moiety masks the IL-12 cytokine or functional fragment thereof thereby reducing or preventing binding of the IL-cytokine or functional fragment thereof to its cognate receptor, but upon proteolytic cleavage of the cleavable linker at a target site, the IL-12 cytokine or functional fragment thereof becomes activated, which renders it capable or more capable of binding to its cognate receptor.
Patent WO-2022081203-A1 (WO)
Inventor: LAWSON AARON DWAYNE
IPC: F16K17/00
Filed: 2021-04-20
Abstract: Disclosed is an apparatus for relieving pressure in a fluid transportation system. Further, the apparatus may include an actuator configured to be mounted onto the handle of the flow control member. Further, the apparatus may include a valve sensor configured to be attached to a pressure relieving valve. Further, the apparatus may include an image capturing device configured to capture an image of a pressure gauge. Further, the apparatus may include a processing device communicatively coupled to the actuator, the valve sensor and the image capturing device. Further, the apparatus may include a storage device communicatively coupled to the processing device. Further, the apparatus may include a wireless transceiver communicatively coupled to the processing device. Further, the apparatus may include a touchscreen display device communicatively coupled to the processing device.
Patent WO-2021217055-A1 (WO)
Inventor: ANDRIOLA PETER
IPC: A61B5/03
Filed: 2021-04-23
Abstract: The present technology relates to intracardiac sensors and associated systems and methods. In some embodiments, the present technology includes a device for monitoring pressure within a patient's heart. The device can include an implantable capacitor having a capacitance value that is variable based on the pressure within the patient's heart and a sensing circuit configured to measure the capacitance value. The device can also include an implantable inductor and a power circuit configured to wirelessly receive power from an external source via the inductor. When the device is in a first configuration, the capacitor can be electrically coupled to the sensing circuit and the inductor can be electrically coupled to the power circuit. When the device is in a second configuration, the capacitor can be electrically coupled to the inductor to form a resonant circuit.
Patent WO-2021226218-A1 (WO)
Title: Systems and methods for communicating with secondary users of a transportation service
Inventor: LURIE RAPHAEL MAX
IPC: G06Q10/02
Filed: 2021-05-05
Abstract: Systems and methods for communicating with secondary users of a transportation service are provided. A method can include obtaining a request for a transportation service including an aerial transport of a first user from a first user device associated with the first user. The method can include generating a first multi-modal transportation itinerary for facilitating the aerial transport for the first user. The method can include obtaining data indicative of a second user that is to travel with the first user for at least a portion of the first multi-modal transportation itinerary and determining a second multi-modal transportation itinerary for facilitating the aerial transport for the second user. The method can include communicating passenger itinerary data indicative of the second multi-modal transportation itinerary to a second user device associated with the second user.
Patent WO-2021231286-A1 (WO)
Title: Coronavirus igg/igm multiplexed dual path immunoassay device
Inventor: ESFANDIARI JAVANBAKHSH
IPC: B01L3/00
Filed: 2021-05-10
Abstract: Test cells with first and second sorbent materials defining a first flow path for a solution, a second flow path distinct from the first flow path for a sample, and a test site with immobilized antigens or antibodies or other ligand-binding molecules located at the junction of the sorbent materials for identifying one or more ligands. In one embodiment, a single highly sensitive immunoassay device is provided that detects the presence in a body fluid sample of two or more COVID-19 (Coronavirus disease 2019) antibodies including immunoglobulin M (IgM) and/or immunoglobulin G (IgG) antibodies to nucleocapsid protein (NP) and spike protein receptor binding domain (RED), and optionally spike protein SI subunit (SI) COVID-19 virus antigens. The immunoassay device is sensitive in detecting early infection using IgM antibody detection and continuing infection using IgG antibody detection. Additionally, successful inoculation is distinguished from infection after inoculation by comparing NP and RED results.
Patent WO-2022182377-A1 (WO)
Inventor: NIEUWOUDT STEPHAN
IPC: H01B5/08
Filed: 2021-05-18
Abstract: Électrode à structure de fil hélicoïdal à ancrage automatique pour la conduction d'énergie vers ou depuis une cible tissulaire dans un corps, composée d'au moins un câble constitué d'un fil biocompatible et conducteur, et entourant un noyau creux à l'intérieur d'un diamètre interne et ayant un axe longitudinal, un diamètre extérieur et deux extrémités, étant souple pour pouvoir se plier automatiquement dans n'importe quelle direction allant jusqu'à 180 degrés sur ledit axe longitudinal, et fixée tout en étant apte à former automatiquement un ancrage de regroupement plus large que le canal d'insertion lorsqu'elle est injectée tandis que son distributeur est sensiblement immobile.
Patent WO-2021242892-A1 (WO)
Title: Systems and apparatuses for patient temperature control with patient heat generation detection
Inventor: VOORHEES MARC
IPC: A61F7/00
Filed: 2021-05-26
Abstract: A patient temperature control system is disclosed that includes a heat exchange system configured to heat or cool a fluid, a circulating pump configured to circulate the fluid through the heat exchanger and at least one interconnectable pad and a control one or more processors and a non-transitory computer-readable medium having stored thereon logic. The logic, when executed by the one or more processors, causes operations including initiation of a targeted temperature management therapy, obtaining of measurements from fluid temperature sensors, a volumetric flow rate sensor and a patient temperature sensor, determining a level of patient heat generation based on one or more of the obtained measurements, and transmitting, via one or more wireless signals, data indicating the level of patient heat generation to a network device.
Patent WO-2022026485-A1 (WO)
Title: Wearable devices with overmolded electronic components and related methods
Inventor: MILLER PHELAN
IPC: B29C45/14
Filed: 2021-07-27
Abstract: The disclosed wearable devices may include a wearable body sized and configured to be worn on a user's body part and at least one electronic component within the wearable body. The wearable body may include a flexible material for wrapping at least partially around the user's body part. The at least one electronic component may be overmolded within the flexible material of the wearable body. Various other methods, systems, and devices are also disclosed.
Patent WO-2022031699-A1 (WO)
Title: Encrypted response timing for presence detection
Inventor: CORNELL BRIAN CLINTON
IPC: H04W12/104
Filed: 2021-08-03
Abstract: A computer-implemented method for verifying identity of an asset can include transmitting, by a first asset, a challenge message at a challenge message transmit time. The challenge message can include a challenge response delay. The method can include receiving, by the first asset, a reply message at a reply message receive time. The reply message can be transmitted from a second asset that is in receipt of the challenge message. The method can include verifying, by the first asset, the second asset based on a comparison of the reply message receive time to a valid reply message receive time span that is based at least in part on the challenge message transmit time and the challenge response delay.
Patent WO-2022031956-A1 (WO)
Title: Use of dexpramipexole for the treatment of moderate to severe asthma
Inventor: PRUSSIN CALMAN PHILIP
IPC: A61K9/00
Filed: 2021-08-05
Abstract: Disclosed herein are methods of treating moderate to severe asthma of the eosinophilic phenotype in a human subject in need thereof with a daily dose of about 75 mg to about 300 mg of dexpramipexole or pharmaceutical acceptable salt thereof, and treating severe asthma of the eosinophilic phenotype in a human subject in need thereof with a daily dose of about 150 mg to about 300 mg of dexpramipexole or pharmaceutical acceptable salt thereof.
Patent WO-2022103472-A1 (WO)
Title: Présentation dynamique d'un contenu visuel lié à une application
Inventor: BI RAN
IPC: H04M1/724
Filed: 2021-08-31
Abstract: La présente invention concerne des procédés et des appareils de présentation dynamique d'un contenu visuel lié à une application sur un écran d'affichage d'un dispositif électronique. Un élément dynamique associé à au moins une application peut être défini dans l'écran d'affichage. Un contenu visuel correspondant aux informations d'état actuel et/ou à un message de notification de l'au moins une application peut être obtenu. Le contenu visuel peut être présenté dans l'élément dynamique.
Patent WO-2022056323-A1 (WO)
Title: Double bearing
Inventor: SCHOENHOLTZ STEPHEN
IPC: F16C33/00
Filed: 2021-09-10
Abstract: Disclosed are bearing assemblies including a compliant layer within a mounting socket for reducing wear of the bearing.
Patent WO-2022103559-A1 (WO)
Title: Architecture de sous-système d'alimentation électrique modulaire
Inventor: COSNER CHRISTOPHER M
IPC: B64G1/50
Filed: 2021-10-20
Abstract: L'invention concerne un système d'alimentation électrique ayant une configuration de batterie double qui permet une alimentation électrique suffisante pour un bus d'engin spatial et un module de charge utile porté par l'engin spatial. Dans un mode d'alimentation par énergie solaire, l'énergie est extraite d'un réseau solaire du bus pour alimenter une charge utile à faible décharge de l'engin spatial et une charge utile à haute décharge d'un module de charge utile. Dans le mode d'alimentation par énergie solaire, une batterie à décharge à faible débit et une batterie à décharge à haut débit sont chargées par une unité de gestion de charge de batterie du bus de l'engin spatial. Dans un mode d'alimentation en cas d'éclipse, la batterie à décharge à faible débit alimente la charge utile à faible décharge de l'engin spatial et la batterie à décharge à haut débit alimente la charge utile à haute décharge du module de charge utile. La batterie à décharge à haut débit peut également être utilisée pour alimenter la charge utile à décharge à haut débit dans le mode d'alimentation par énergie solaire pour satisfaire à ses exigences élevées en courant afin de satisfaire à des opérations de mission flexible.
Patent WO-2022094162-A1 (WO)
Title: Membranes fabriquées à l'aide de poudres fines
Inventor: O'BRIEN GREGORY S
IPC: C08L27/16
Filed: 2021-10-29
Abstract: La présente invention permet la production de membranes TIPS haute résistance et haute perméabilité à l'aide de charges extractibles avec des grades PVDF en poudre fine.
Patent WO-2022109073-A1 (WO)
Title: Facteur de croissance nerveuse indolore pour réparation de fractures
Inventor: BAHNEY CHELSEA
IPC: A61P19/00
Filed: 2021-11-17
Abstract: La présente divulgation concerne des méthodes de stimulation de la consolidation d'une fracture osseuse comprenant l'administration d'une composition pharmaceutique contenant des supports de biomatériau présentant un facteur de croissance nerveuse (NGF) indolore.
Patent WO-2022132491-A1 (WO)
Title: Stable pigment dispersion composition
Inventor: COULBECK ELLIOT
IPC: C09K23/42
Filed: 2021-12-07
Abstract: A method for forming a pigment dispersion that is stable at elevated temperatures is provided, wherein the dispersion contains a pigment, solvent, and dispersant that is a salt of a polyether functionalized polyacid.
Patent WO-2023055409-A1 (WO)
Title: Sélection de données de modèle de langage à grande échelle pour reconnaissance vocale de mots rares
Inventor: HUANG RONNY
IPC: G10L15/16
Filed: 2021-12-13
Abstract: Un procédé d'apprentissage d'un modèle de langage (206) pour la reconnaissance vocale de mots rares consiste à obtenir un ensemble d'échantillons de texte d'apprentissage (422), et à obtenir un ensemble d'énoncés d'apprentissage (452) utilisés pour l'apprentissage d'un modèle de reconnaissance vocale. Chaque énoncé d'apprentissage dans la pluralité d'énoncés d'apprentissage comprend des données audio (454) correspondant à un énoncé et une transcription correspondante (456) de l'énoncé. Le procédé consiste également à appliquer un filtrage de mots rares sur l'ensemble d'échantillons de texte d'apprentissage pour identifier un sous-ensemble d'échantillons de texte d'apprentissage de mots rares (432) qui comprennent des mots qui n'apparaissent pas dans les transcriptions à partir de l'ensemble d'énoncés d'apprentissage ou apparaissent dans les transcriptions à partir de l'ensemble d'énoncés d'apprentissage inférieurs à un nombre seuil de fois. Le procédé comprend en outre l'apprentissage du modèle de langage externe sur les transcriptions à partir de l'ensemble d'énoncés d'apprentissage et du sous-ensemble identifié d'échantillons de texte d'apprentissage de mots rares.
Patent WO-2022026983-A1 (WO)
Inventor: DAUGHERTY CHARLES RICHERD
IPC: A45D29/18
Filed: 2021-07-21
Abstract: As shown in one preferred embodiment, a two-blade vice-type nail clipper comprising a thin safety-cover-guard with ergonomic upward angle and wrap-around safety edges, that is permanently mounted just below said nail clipper's lower cutting blade and that follows or mirrors the shape of said nail clipper's lower cutting surface, including wrapping around the sharp sides, comers and edges of said lower cutting surface, so as to provide an industry advancing level of nail cutting safety with minimal invasiveness.
Patent WO-2022040653-A1 (WO)
Inventor: STEIN EYAL
IPC: B64D47/00
Filed: 2021-07-27
Abstract: An unmanned aerial vehicle (UAV) or "drone" executes a neural network to assist with inspection, surveillance, reporting, and other missions. The drone inspection neural network may monitor, in real time, the data stream from a plurality of onboard sensors during navigation to an asset along a preprogrammed flight path and/or during its mission (e.g., as it scans and inspects an asset). A HAPS platform may execute a neural network (a "HAPSNN") as it monitors air traffic; the neural network enables it to classify, predict, and resolve events m its airspace of coverage in real time as well as learn from new events that have never before been seen or detected. The H AP 8NN -equipped HAPS platform may provide surveillance of nearly 100% of air traffic in its airspace of coverage, and the HAPSNN may process data received from a drone to facilitate safe and efficient drone operation within an airspace.
Patent WO-2022073010-A1 (WO)
Title: Harq feedback transmission for sidelink communication in unlicensed spectrum
Inventor: WU SHUANSHUAN
IPC: H04L1/18
Filed: 2021-09-29
Abstract: In one aspect, a method of wireless communication includes receiving, by a user equipment (UE), a sidelink transmission in a first slot of an unlicensed channel. The method also includes performing, by the UE, a Channel Access (CA) operation for a hybrid automatic repeat request (HARQ) feedback transmission in a second slot for the sidelink transmission, where the second slot is one of multiple slots configured for HARQ feedback for the sidelink transmission. The method further includes transmitting, by the UE, HARQ feedback transmission in the second slot based on successfully performing the CA operation. Other aspects and features are also claimed and described.
Patent WO-2022159486-A1 (WO)
Inventor: GU ZHEN
IPC: A61K38/28
Filed: 2022-01-19
Abstract: Un timbre à micro-aiguilles à cristaux colloïdaux sensible au glucose (GCC-MN) à invasion minimale est divulgué, destiné à la surveillance du glucose à l'œil nu. Le timbre (GCC-MN) est conçu avec un noyau en résine ou polymère pour supporter mécaniquement une enveloppe de matériau cristallin colloïdal sensible au glucose permettant de détecter le glucose et de rendre compte des concentrations de glucose ou des changements de concentration. Le timbre GCC-MN pourrait traduire les concentrations de glucose en changements de couleur visibles à l'œil nu en environ 5 min, et une telle réactivité au glucose est réversible. Démontrés dans un modèle de souris diabétique de type 1, les procédures d'extraction de fluide interstitiel, de détection de glucose et d'affichage de couleurs associées au glucose résultantes sont réalisées simultanément avec ce timbre GCC-MN.
Patent WO-2022204099-A1 (WO)
Title: Carboxy substituted glucocorticoid receptor agonists
Inventor: STITES RYAN EDWARD
IPC: A61P17/00
Filed: 2022-03-22
Abstract: The present invention provides a compound of Formula I: (I) wherein R1 is H, halogen, C1-C3 alkyl, or C1-C3 alkoxy; R2 is H or halogen; and X is O, OCH2, or CH2, or a pharmaceutically acceptable salt thereof, wherein the compound of Formula I, or pharmaceutically acceptable salt thereof is useful for treating autoimmune and inflammatory diseases, such as atopic dermatitis, rheumatoid arthritis, and lupus nephritis.