baber/WOPTO huggingface dataset:
Patent EP-0904395-B2 (EP)
Inventor: DELUCA NEAL A
IPC: C12N5/10
Filed: 1997-05-22
Granted: 2011-07-27
Abstract: Cell lines that express complementing levels of herpes simplex virus (HSV) essential immediate early proteins ICP4 and ICP27 as well as ICP4, ICP27 and ICP0 and a method of producing the novel cell lines are disclosed. These cell lines are utilized to provide HSV strains deficient for both (a) ICP4 and ICP27; (b) ICP4, ICP27, ICP22; (c) ICP4, ICP27, ICP0; and, (d) ICP4, ICP27, ICP22 and ICP0, and their generation, and HSV strains deficient for (a) ICP4 and ICP27; (b) ICP4, ICP27, ICP22; (c) ICP4, ICP27, ICP0; and, (d) ICP4, ICP27, ICP22 and ICP0, and one or more additional genes, and their generation. Vectors are provided from these methods of using these HSV strains for gene transfer and for producing site-specific homologous recombination with cellular DNA.
Patent JP-H0699583-B2 (JP)
IPC: B29C48/08
Filed: 1990-04-18
Abstract: Objects of thermoplastic polymer foam such as, e.g., sheeting of polyolefins such as polyethylene, are treated at elevated temperatures effective to rapidly purge the foam of a substantial portion of the residual blowing agent. Significant economies are achieved by reducing the amounts of residual blowing agents (such as flammable, toxic or environmentally hazardous gases) to levels presenting no fire hazard or other safety hazards in times substantially less than required in conventional aging under ambient conditions. The processes can be carried out in ovens or other heating zones which form continuations of the basic production line, with the extracted blowing agents recycled or disposed of by combustion.
Patent JP-H07103315-B2 (JP)
IPC: C07D491/14
Filed: 1989-04-27
Abstract: The lactone compounds have the formula 
<IMAGE>
 in which
 Ar denotes an aryl radical which is unsubstituted or substituted by halogen, nitro, cyano, lower alkyl, lower alkoxy, lower alkylthio, lower alkoxycarbonyl, trifluoromethyl, phenoxy, phenylthio or -NX3X4,
 R1 denotes hydrogen, halogen, lower alkyl or lower alkoxy,
 R2 denotes lower alkyl, phenyl or phenyl which is substituted by halogen, lower alkyl or lower alkoxy, and
 X1, X2, X3 and X4, independently of one another, each denote hydrogen, unsubstituted or halogen-, hydroxyl-, cyano-, tetrahydrofuryl- or lower alkoxy-substituted alkyl, acyl, cycloalkyl or unsubstituted or halogen-, cyano-, nitro-, trifluoromethyl-, lower alkyl-, lower alkoxy- or lower alkoxycarbonyl-substituted aralkyl or aryl or the substituent pairs (X1 and X2) and (X3 and X4) each together with the joint nitrogen atom denote a five- or six-membered, preferably saturated, heterocyclic radical, and
 the ring A is unsubstituted or substituted by halogen, nitro, lower alkyl, lower alkoxy, lower alkylthio, lower alkoxycarbonyl, amino, mono(lower alkylamino) or di(lower alkylamino). 
<??>These novel lactone compounds are suitable in particular as colour formers in pressure-sensitive or heat-sensitive recording materials and produce intensive yellow, orange or red colourations.
Patent JP-H0569806-B2 (JP)
Inventor: ADORUFU KUNEKUSUTO
IPC: A01N25/00
Filed: 1982-06-25
Abstract: 1. Process for the time controlled release of active substances from sustained-release active substance preparations, in particular drug preparations, by addition of hydrophilic polymers characterized in that the release rate which is rising as a result of increasing viscosity steps of the hydrophilic polymers added is empirically determined and the desired release characteristic is adjusted using the values determined.
Patent JP-H0764090-B2 (JP)
IPC: B41J2/00
Filed: 1987-05-15
Abstract: In a video printer, a suffer memory for memorizing picture data corresponding to one line includes a memory addressed by a first address and a second address. And the video printer includes a memory write circuit having a first address generation circuit for generating a first address depending upon gradation of picture data on the basis of inputted picture data and for supplying said first address to the memory and a second address generation circuit for generating an address signal depending upon the number of printing dots of the thermal head and for supplying said address signal to the memory. The video printer also includes a memory read circuit for successively generating the second address for each of the first address and supplying the second address to the memory.
Patent JP-3093434-B2 (JP)
IPC: C08L77/10
Filed: 1992-03-27
Granted: 2000-10-03
Abstract: A novel miscible blend of component polymers comprised of from about 5 weight percent to about 95 weight percent of a polybenzimidazole and from about 95 weight percent to about 5 weight percent of an aromatic polyamide aromatic polyamide-hydrazide or aromatic polyamide containing heterocyclic linkages. Miscibility of the component polymers of the blend is indicated by infrared, X-Ray and Differential Scanning Calorimetry analyses and scanning electron photomicrographs. In a film or molded article of a blend mostly comprised of a polybenzimidazole, it is preferred that the aromatic polyamide, aromatic polyamide-hydrazide or aromatic polyamide containing heterocyclic linkages be present in the blend in an amount sufficient to result in a blend with improved tensile properties compared to the polybenzimidazole and that is more thermally processable than the polybenzimidazole. In a blend mostly comprised of an aromatic polyamide, aromatic polyamide-hydrazide or aromatic polyamide containing heterocyclic linkages, it is preferred that the polybenzimidazole be present in the blend in an amount sufficient to result in a blend with increased thermal stability and nonflammability compared to the aromatic polyamide, aromatic polyamide-hydrazide or aromatic polyamide containing heterocyclic linkages. The blends, particularly in the form of films or molded articles, may be post-treated with heat or sulfonating agent in order to minizime their shrinkage when subsequently subjected to heat and in order to increase their resistance to solvrnts and acids.
Patent JP-H0442106-B2 (JP)
IPC: B22D31/00
Filed: 1984-06-30
Abstract: A process for producing a casting mould with chemically bound moulding material using a pattern is intended to make it possible to forego the use of clay-bound sand, in particular for the mass production of cast members, and to provide a casting mould of adequate gas permeability, which is simple to produce, with a low level of consumption of moulding material, and inexpensive, and which also provides a high level of casting quality wth a low degree of environmental pollution. For that purpose, the moulding material which has become pourable or fluid due to the operation of casting a cast member is removed from a first casting mould comprising a single moulding material, whereas the remaining portion of the moulding material is left, and the hollow space formed when the pattern is re-fitted is filled with moulding material. In addition, the moulding material which has been reduced in strength may be also removed, being for example blown or brushed out.
Patent JP-H0627098-B2 (JP)
IPC: C07D307/32
Filed: 1988-06-08
Abstract: A novel three-step process for preparing 4-(3,4-dichlorophenyl)-4-phenylbutanoic acid is disclosed, which involves (1) reducing 4-(3,4-dichlorophenyl)-4-ketobutanoic acid to 4-(3,4-dichlorophenyl)-4-hydroxybutanoic acid; (2) then converting the intermediate hydroxy acid formed in the first step to 5-(3,4-dichlorophenyl)-dihydro-2(3H)-furanone, and (3) thereafter reacting the resulting gamma-butyrolactone compound with benzene in a Friedel-Crafts type reaction to form the desired final product. The latter compound is known to be useful as an intermediate leading to 4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenone and ultimately, to cis-(1S)(4S)-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrah ydro-1-naphthaleneamine (sertraline), which is known to be a preferred anti-depressant agent in the field of medicinal chemistry. The aforementioned 5-(3,4-dichlorophenyl)-dihydro-2(3H)-furanone and 4-(3,4-dichlorophenyl)-4-hydroxybutanoic acid are both novel compounds. There is also disclosed a novel process for converting 5-(3,4-dichlorophenyl)-dihydro-2(3H)-furanone directly to 4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenone, as well as an alternate novel process for converting 4-(3,4-dichlorophenyl)-4-hydroxybutanoic acid directly to this same key intermediate.
Patent JP-H0431679-B2 (JP)
IPC: C12Q1/26
Filed: 1983-08-23
Abstract: A process for the production of a diagnostic device which is envisaged, in particular, for the detection of a pathologically increased concentration of dehydrogenases in fluids of humans, animals or plants and consists of a carrier and a substance mixture, in which, in each case with exclusion of UV radiation, the substance mixture, which has been adjusted to a pH value in the acid range, is brought into contact, in liquid form, with the carrier and the combination of carrier and substance mixture is subsequently dried and then enclosed in a packaging casing which is opaque to light of higher energy than red light. The process has the peculiarity that the dried combination of carrier and substance mixture in the packaging casing is securely sealed against entry of air and moisture. The device thus produced can be stored for a long time before use, without its ability to function being substantially changed.
Patent JP-3268535-B2 (JP)
IPC: A41D27/10
Filed: 1991-06-03
Granted: 2002-03-25
Abstract: The present invention provides surgical gowns and other garments possessing the advantages of raglan sleeve construction in terms of comfort and freedom of movement, with improved manufacturing efficiency. The garment (100) of the present invention provides a raglan sleeve divided into an upper portion (20) and lower portion (30) joined approximately in the area of the bicep. Waste is greatly reduced by creating a shoulder portion from material removed to form the arm openings in the body portion of the garment. The shoulder portion (20) is attached to the body portion of the garment to form a raglan shoulder portion which extends to about the bicep of the wearer. A sheet of material is cut in a trapezoidal pattern to form a plurality of lower sleeve portions, each of which is attached to a shoulder portion. Gowns made in accordance with the present invention exhibit the flow and shoulder lines of a raglan sleeve construction while making efficient use of the fabric from which the gown is constructed. Methods of making garments such as surgical gowns are also disclosed. <IMAGE>
Patent JP-3376027-B2 (JP)
IPC: D06B11/00
Filed: 1993-07-02
Granted: 2003-02-10
Abstract: An object is to provide ink jet printed products superior in the image quality such that ink jet printing onto the cloths satisfy the various conditions regarding the density, resolution, blurring, graininess of dot. To accomplish this object, when an image is formed by a number of dots obtained by discharging the ink from a print head to attach the ink onto the cloths, the ink amount discharged from the printing head onto the cloths is controlled to produce ink jet printed products so that the average value of equivalent circle diameter for each dot after image formation may be three-fourths or less the average value of diameters of fibers constituting said cloths. Thereby, ink jet printed products excellent in image quality can be obtained with blurs reduced and high graininess of dot. <IMAGE>
Patent JP-2519252-B2 (JP)
IPC: G01N33/546
Filed: 1987-07-08
Granted: 1996-07-31
Abstract: Dispersion polymers composed of latex, which have on the particle surface a copolymer composed of monomers having terminal acetals of the formula I CH2=CR1-CO-NH-(CH2)n-CH(OR2) (OR3) I in which n=1-6; R1=H or CH3, and R2 and R3 are identical or different with R2 and R3=-(CH2)m-CH3 (m=0-7) or R2 and R3=-CXYZ, X, Y and Z being (CH2)p-CH3 and p being 1-3, with X, Y, Z being identical or different, and betaine compounds of the formula II CH2=CR-(CH2)a-(CO-X)b-Z-(CH2)c-Y II with R=H or CH3, X=-NH or -0, Y=SO3- or COO-   <IMAGE>  or  <IMAGE>  a=0-6, b=0-1, c=1-12, are very suitable for the preparation of biologically active latex reagents which have a particularly high detection sensitivity and stability.
Patent JP-3105834-B2 (JP)
IPC: F23M5/00
Filed: 1997-06-30
Granted: 2000-11-06
Abstract: A process for the preparation of hydrogen bromide by the direct combustion of bromine in hydrogen, as in the reaction :-H2 + Br2 -> 2HBr -by the following stages :- -the forming of an intimate mixture of hydrogen and a combustion supporter in a chamber at a pressure equal or more than atmospheric ; -ignition of the mixture at the exit of the mixing chamber ; -replacement of part or all of the combustion supporter by a current of vapourised bromine at an appropriate H2/Br2 molar ratio to maintain a stable flame at the exit of the chamber and in a combustion zone to obtain a complete combustion of the bromine ; -cooling of the gases in a cooling zone ; then -recovery of the gaseous hydrogen bromide current at 1 bar absolute(min.) and at 125 degrees C. maximum. Also claimed, is the installation for effecting the process.
Patent JP-4012627-B2 (JP)
IPC: G03F7/004
Filed: 1998-07-07
Granted: 2007-11-21
Abstract: PROBLEM TO BE SOLVED: To provide a composition containing a photosensitizer excellent in preservation stability and high in sensitivity to laser beams of long wavelength by containing a specific dipyrromethene boron complex as the photosensitizer. SOLUTION: This composition contains a dipyrromethene boron complex expressed by a formula, as a photosensitizer. This photosensitizer is excited by absorbing light in a visible light area of 400-700 nm, particularly 400-600 nm, and interacts with resin and a photo-acid generating agent. In the formula, R1-R7 independently represent hydrogen atom, halogen atom, nitro group, cyano group, hydroxy group, amino group, carboxyl group, sulfonic acid group, alkyl group, halogenoalkyl group, alokoxyalkyl group or the like; R4 represents hydrogen atom, cyano group, alkyl group, aralkyl group, aryl group, heteroaryl group or the like; R8 represents alkyl group, aryl group or aralkyl group; and R9 represents halogen atom, alkoxy group, aryloxy group or the like.
Patent JP-H0692407-B2 (JP)
IPC: C07D473/34
Filed: 1986-08-18
Abstract: The present invention provides N6-disubstituted purine derivatives of the general formula:    <IMAGE>  (I)  wherein R1 and R4 are the same or different and each represents a hydrogen or halogen atom or an -NR6R7 group, R2 and R3 are the same or different and each represents a C1-C6 alkyl radical, a C2-C6 alkenyl radical, a C3-C7 cycloalkyl radical, a phenalkyl radical containing up to 4 carbon atoms in the alkyl moiety, which can be straight-chained or branched, the phenyl moiety of which can be substituted one or more times by halogen, hydroxyl, C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkylthio or trifluoromethyl; a furylmethyl or furylethyl radical, a thiophenemethyl or thiopheneethyl radical, a pyridylmethyl or pyridylethyl radical optionally substituted by a C1-C4 alkyl radical, an indanyl radical or a tetrahydronaphthyl radical, R5 is a hydrogen atom, a tetrahydrofuranyl or tetrahydropyranyl radical or a C1-C10 radical which is optionally substituted one or more times by hydroxyl, C1-C6 alkanoyloxy, C1-C6 alkoxycarbonyl, C2-C6 carboxyalkanoyloxy, C2-C6 hydroxyalkoxy, C3-c6 dihydroxyalkoxy, carboxyl, cyano or 1H-tetrazol-5-yl radical, R6 and R7 are the same or different and each represents a hydrogen atom or a C1-C6 alkyl radical or together represent a C2-C5 alkylene radical optionally interrupted by oxygen, sulphur or an NR8 group and R8 is a hydrogen atom or a C1-C6 alkyl radical; as well as the pharmacologically acceptable salts thereof.
Patent JP-H0352001-B2 (JP)
IPC: G01C3/00
Filed: 1984-09-20
Abstract: PURPOSE:To obtain the distance from an object at every picture element regardless of the accuracy of the distance, by picking up the surface image of the object, of which the spectrum pattern image was picked up, through a color filter for controlling the quantity of transmitted light at every wavelength and performing the operation between a plurality of picked-up images. CONSTITUTION:The light from a white light source 12 is spectrally diffracted by a prism 14 through a slit 13 and a spectrum pattern, of which the angle alphais the nomotone function of a wavelength lambda, is projected to an object surface 5 and the scene thereof is formed to the image forming surface 9 of a camera 7 through a filter 15 and a lens 8. Then, the signal intensity of the point P' on the surface 9, which is the image at the point P on the surface 5 illuminated by monochromatic light with a wavelength lambda, is calculated and, subsequently, the signal intensity at the point P' is calculated similarly by replacing the filter 5 with a second filter 15 having different transmissivity and, from the ratio of both intensities being the function of only the wavelength lambda, a projection angle alpha is calculated. Further, the light directional angle beta to the camera 7 is calculated from the position of the picture element at the point P' and the distance L between the camera 7 and the object surface 5 is calculated.
Patent JP-H0412274-B2 (JP)
IPC: C07D487/14
Filed: 1983-10-21
Abstract: The new compounds are compounds of formula (I) <CHEM>  and its tautomer and the pharmaceutically acceptable salts thereof,  wherein R<1> and R<2> are the same or different and are hydrogen, alkyl, cycloalkyl, alkenyl, alkynyl, aryl; alkyl substituted by cycloalkyl, aryl or heterocyclic radical; R<3> is hydrogen, alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, acyloxyalkyl, oxoalkyl, aryl; alkyl substituted by cycloalkyl, cycloalkenyl, aryl, hydroxy, cyano, halo or heterocyclic radical: -alkyl-X-CnH2n-1 wherein X is O,S,S<+>-O<->, SO2 or -N-CpH2p-1; -(CH2)qC(O)NR<6>R<7> or -(CH2) C(O)OR<8>; R<4> is hydrogen, alkyl, aryl, a heterocyclic radical; or alkyl substituted by cycloalkyl aryl or a heterocyclic radical,  R<5> is hydrogen acyl, or alkyl. These compounds are useful as antiinflammatory agents for treating inflammatory conditions such as arthritis, spondylitis, and tendonitis in mammals.
Patent JP-H0710768-B2 (JP)
IPC: A61K8/00
Filed: 1983-10-28
Abstract: A film-forming cosmetic composition useful as a facial pack, nail enamel, eye liner etc., which comprises a copolymer of vinyl alcohol and alkyl vinyl ether, being referred to simply as PVA/AVE, consisting of 98 to 80 mole% of vinyl alcohol monomer units and 2 to 20 mole% of linear or branched alkyl vinyl monomer units having from 1 to 6 carbon atoms.The molar ratio of the vinyl alcohol monomer units to the alkyl vinyl ether monomer units is in the range of from 95/5 to 85/15.The PVA/AVE according to the invention has no acetic groups with ester bonds in a molecule. Instead, there are alkyl or alkenyl groups having ether bonds which serve for steric hindrance for preventing gelation of an aqueous solution of such copolymer. From this reason, the PVA/AVE does not undergo any hydrolysis as time passes and is thus excellent in storage stability.
Patent JP-H0784362-B2 (JP)
IPC: A01N31/08
Filed: 1989-08-07
Abstract: Medical instruments, which may include brass, copper, aluminum, stainless steel, carbon steel, or plastic parts are sterilized or disinfected in an anti-microbial solution. The anti-microbial effect of a strong oxidizing agent, such as peracetic acid, is improved with a wetting agent. The solution further includes a triazole or other component for inhibiting the corrosion of copper and brass. Phosphates or other buffering agents adjust the oxidizing agent generally to a neutral pH for preventing the corrosion of steel. Molybdates or analogous compounds also buffer the pH and inhibit corrosion of aluminum by the oxidizing agent. The corrosion inhibiting is enhanced by the wetting agent. Optionally, a sequestering agent is provided for inhibiting hard water precipitation.
Patent JP-H0477742-B2 (JP)
IPC: A61K31/22
Filed: 1984-10-19
Abstract: A compound represented by the formulawherein R' represents a hydroxyl group, an alkanoyloxy group or a group of the formulain which R<sup>2</sup> represents a hydrogen atom or a lower alkyl group, and R<sup>3</sup> represents a hydrogen atom, a lower alkyl group, an alkanoyl group, a phenyl group, a carbamoyl group or a thiocarbamoyl group, or a salt thereof.The said compound can be prepared by reacting a compound represented by the formulawith a compound of the formulawherein R' is as defined hereinabove, or a salt thereof, and as required, alkanoylating the resulting compound of formula (I) in which R' represents a hydroxyl group or an amino group, and as required, converting the resulting compound of formula (I) in which R' is the groupinto its salt, and is useful for the treatment of inflammation, pain or rheumatism.
Patent JP-3302645-B2 (JP)
IPC: C08G77/14
Filed: 1998-08-04
Granted: 2002-07-15
Abstract: PROBLEM TO BE SOLVED: To provide a new liquid crystal alignment layer having a alignment thermal stability and a wide visual field angle, which is an extremely thin film having a nanometer-lever thickness and excellent in alignment control power and which can be uniformly and strongly fixed on a substrate and produced with a good producibility, and to provide a liquid crystal display element using the same. SOLUTION: The liquid crystal alignment layer has a liquid crystal regulating power capable of allowing liquid crystal molecules to align in a specified direction and is fixed directly or via an other material layer by -Si-O- bonding on a substrate 1 having an electrode. The liquid crystal alginment layer is comprised of a thin film in the form of a monomolecular layer containing a chemical bonding unit having a specific group of the formula.
Patent JP-4104791-B2 (JP)
IPC: C08L83/04
Filed: 1999-08-10
Granted: 2008-06-18
Abstract: The present invention provides a cosmetic which is superior in both characteristics of feel and spread at the time of application. The cosmetic is a cosmetic comprising an amphoteric urethane resin having carboxyl group(s) and tertiary amino group(s) in a molecule, and a silicone polymer.
Patent JP-2922610-B2 (JP)
IPC: B60Q1/12
Filed: 1990-09-11
Granted: 1999-07-26
Abstract: PURPOSE:To maintain the light distributional condition at the time of linear running by returning the rotational angle of a servomotor to a motor central that is preliminarily set, each time that power source connection to the light source of a headlight device is cancelled. CONSTITUTION:A bank angle thetab of a motorcycle is calculated by a bank angle calculation means 203A through multiplying (steering angle thetah) by (car velocity V). A motor control amount thetam is calculated using the angle thetab by a motor control amount calculation means 204. A motor control angle thetam0 is calculated by a motor control means 205 from the control amount thetam and a motor center value thetamc that is preliminarily stored in a motor center value memory means 215, while by using the motor control angle and a motor actual rotational angle thetam1 output from a motor rotational angle sensor 33, a servomotor 18 is feedback-controlled. When the OFF-condition of a combination switch 49 is detected by a cut power source detection means 132A, a constant voltage circuit 47 is separated after a preset period of time has passed. When the OFF condition of the switch 49 is detected, a motor returning means 141A is energized, and the servomotor 18 is controlled in such a way that the rotational angle of the servomotor 18 becomes the motor center value thetamc.