baber/WOPTO huggingface dataset:
Patent CA-2365907-C (CA)
Title: Enhancement of the immune response for vaccine and gene therapy applications
Inventor: POLO JOHN M
IPC: C12N15/79
Filed: 2000-04-07
Granted: 2010-08-17
Abstract: Expression cassettes are provided comprising a promoter operably linked to a nucleic acid molecule which, when transcribed in vivo, forms double-stranded RNA that induces the production of interferon. Expression cassettes also are provided comprising a promoter operably linked to a ribozyme or antisense nucleic acid molecule which, when transcribed in vivo, forms a ribozyme or antisense RNA molecule that stimulates an immune response. In addition, expression cassettes are provided comprising a promoter operably linked to a ribozyme or antisense nucleic acid molecule which, when transcribed in vivo, stimulates apoptosis. Finally, gene delivery vectors are provided which contain such expression cassettes, host cells containing the gene delivery vectors, and methods of utilizing the expression cassettes, gene delivery vectors, and host cells.
Patent CA-2374890-C (CA)
Title: Systeme anticorrosion de fermeture de fenetre
Inventor: DE MARCO GIUSEPPE
IPC: E05D7/04
Filed: 2002-03-06
Granted: 2007-04-10
Abstract: Cet élément de fermeture d'un système de fermeture servant à verrouiller le vantail au cadre d'une fenêtre est constitué d'une portion rectangulaire allongée rigide et résistant à la rouille qui comprend au moins deux feuilles métalliques juxtaposées résistant à la rouille. L'élément de fermeture est créé en pliant au moins une feuille métallique d'une épaisseur comprise entre 0,25 mm et 2 mm (préférablement entre 0,25 mm et 1 mm), soit en repliant une partie latérale de la feuille contre une partie adjacente afin de former une structure stratifiée. Afin d'éviter d'avoir des bords latéraux coupants potentiellement dangereux, les parties latérales longitudinales de la feuille d'acier inoxydable peuvent être pliées vers l'intérieur, sur la partie centrale de la feuille, en repliant deux joints pliés parallèles et longitudinaux. L'élément de fermeture peut servir à verrouiller le vantail à la fenêtre en l'intégrant à un bras pivotant, à une charnière ou à une armature de liaison amovible servant à verrouiller ou déverrouiller le vantail. De préférence, l'élément de fermeture comprend une ou plusieurs gâches permettant de maintenir les couches métalliques afin d'éviter qu'elles se déplacent sur le côté. Les gâches appropriées peuvent notamment être des cames qui entraînent une partie de chaque couche métallique extérieure afin d'éviter qu'elles ne s'éloignent les unes des autres. Selon l'utilisation souhaitée de l'élément de fermeture, la gâche peut comprendre un ou plusieurs tétons de blocage ou à ressort ou d'autres fixations pivotantes adéquates.
Patent CA-2381100-C (CA)
Title: Vehicle brake status indicating apparatus
Inventor: SHEPHERD ROBERT W
IPC: F16D66/00
Filed: 2000-06-30
Granted: 2010-01-12
Abstract: In a vehicle braking system having a slack adjuster (1) with an actuator (7) and an electrically operable car control unit (40) an electrical switch (26) is responsive the position of the actuator (7) and is coupled to the car control unit (40) to provide an indication of the condition of the vehicle brake shoes, i.e. whether or not the brake shoes are disengaged from the vehicle wheels.
Patent CA-2381580-C (CA)
Inventor: GUBLER SCOTT A
IPC: A23G4/12
Filed: 2000-06-02
Granted: 2009-10-27
Abstract: The present invention provides a process for preparing a chewing gum tablet, in which a chewing gum composition is cooled to a temperature at which the composition is brittle, and the composition is ground while brittle to form a fine powder. In a preferred process, the composition is cooled by mixing with a coolant, such as solid carbon dioxide, and the mixture is ground to a powder. The powder can be mixed with a pharmaceutical active ingredient capable of topical absorption in the buccal cavity or in the mucous layer of the upper or lower intestinal tract, and formed into a tablet.  Preferably, the mixture of the powder, pharmaceutical active ingredient, and other additives such as coating agents, binders, additional active ingredients, and sweeteners, are granulated in a fluidized bed granulator prior to forming the mixture into a tablet. The resulting tablet provides a dosage form of the pharmaceutical active ingredient having a more accurate and uniform dose of the active ingredient.
Patent CA-2382999-C (CA)
Title: Pedestrian navigation method and apparatus operative in a dead reckoning mode
Inventor: LADETTO QUENTIN
IPC: G01C22/02
Filed: 2002-04-22
Granted: 2010-06-22
Abstract: A displacement of a pedestrian is determined from his or her accelerations by detecting accelerations which are substantially non vertical, determining a characteristic feature in the detected accelerations correlated with a step frequency, determining the displacement on the basis of said determined characteristic. The acceleration data can be submitted to waveform analysis to determine an actualized time interval of an occurring feature, such a maximum values, from which it is determined whether the actualized time period falls within determined limit values. The currently detected characteristic feature is then determined as corresponding to a displacement step if the actualized time period falls within said determined limit value. By using non-vertical acceleration measurements, the invention can make it possible to distinguish between forward, backward, left and right stepping movements and take these into account for the navigation.
Patent CA-2383174-C (CA)
Title: Method of treating cardio pulmonary diseases with no group compounds
Inventor: STAMLER JONATHAN S
IPC: A61K33/00
Filed: 2000-08-18
Granted: 2012-01-24
Abstract: Treatment of pulmonary disorders associated with hypoxemia and/or smooth muscle constriction and/or inflammation comprises administering into the lungs as a gas a compound with an NO group which does not form NO2/NOx in the presence of oxygen or reactive oxygen species at body temperature. Treatment of cardiac and blood disorders, e.g., angina, myocardial infarction, heart failure, hypertension, sickle cell disease and clotting disorders, comprises administering into the lungs as a gas, a compound which reacts with cysteine in hemoglobin and/or dissolves in blood and has an NO group which is bound in said compound so that it does not form NO2/NOx in the presence of oxygen or reactive oxygen species at body temperature. Exemplary of the compound administered in each case is ethyl nitrite. Treatment of patient in need of improved oxygenation, blood flow of and/or thinning of blood comprises providing in the patient a therapeutic amount of red blood cells loaded with nitrosylated hemoglobin. A method is directed to screening drugs that increase level of nitrosoglutathione in airway lining fluid.
Patent CA-2383424-C (CA)
Title: Novel b7-4 molecules and uses therefor
Inventor: FREEMAN GORDON
IPC: C12N15/09
Filed: 2000-08-23
Granted: 2011-02-15
Abstract: The invention provides isolated nucleic acids molecules, designated B7-4 nucleic acid molecules, which encode novel B7-4 polypeptides. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing B7-4 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a B7-4 gene has been introduced or disrupted. The invention still further provides isolated B7-4 proteins, fusion proteins, antigenic peptides and anti-B7-4 antibodies. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.
Patent CA-2383876-C (CA)
Inventor: GUPTA AMITAVA
IPC: A61F2/16
Filed: 2000-08-25
Granted: 2007-04-03
Abstract: The present provides progressive addition lens designs and lenses in which unwanted lens astigmatism is reduced as compared to conventional progressive addition lenses.
Patent CA-2385847-C (CA)
Title: Electrode plane pour dispositif d'hydroelectrolyse, ensemble de ces electrodes, membrane electrolytique solide, et element electrolytique
Inventor: HIRAI KIYOSHI
IPC: C25B1/06
Filed: 2000-09-25
Granted: 2009-01-06
Abstract: L'invention porte sur une électrode plane pour dispositif d'hydroélectrolyse formée à partir d'une plaque métallique d'une épaisseur permettant le formage à la presse et qui comporte une partie plane et un rebord périphérique replié de manière à créer des parties en saillie et des parties en creux.
Patent CA-2392287-C (CA)
Inventor: YOKOZEKI ICHIRO
IPC: H05B6/14
Filed: 2002-06-28
Granted: 2005-05-10
Abstract: An induction heating roller apparatus that varies temperature distribution in the axial direction of a heating roller. The apparatus includes a heating roller and a plurality of induction coils arranged separately along an axial direction of the heating roller. The heating roller includes a secondary coil that is air-core transfer coupled to the induction coils. The apparatus further includes a plurality of capacitors, each being connected to one of the induction coils to form a resonance circuit. At least one of the resonance circuits has a resonance point that differs from the remaining resonance circuits.
Patent CA-2394699-C (CA)
Inventor: MATTERN CLAUDIA
IPC: A61D7/00
Filed: 2000-12-04
Granted: 2008-04-08
Abstract: The invention relates to an apparatus for injecting an active substance formulation in domestic animals, in which the apparatus comprises an injection device designed in such a way that the hypodermic needle penetrates the upper, but not the lower skin layers, and an active substance formulation with an antiparasitically active substance in a formulation suitable for injection purposes.
Patent CA-2395029-C (CA)
Inventor: HAYASHI KANJI
IPC: B62K21/08
Filed: 2002-07-25
Granted: 2006-08-29
Abstract: In a steering damper utilizing hydraulic pressure, even if generation of damping force is controlled in correspondence with external force inputted to a handle upon external perturbations and the like, the damping force changes due to change in liquid temperature of working liquid. Accordingly, to precisely control the damping force, correction based on change in liquid temperature of the working liquid is required. However, to measure the change in liquid temperature of the working liquid, it is necessary to provide particular measurement means requiring a complicated structure, which increases the number of parts and costs.      Accordingly, the present invention has an object to provide a steering damper which can easily temperature-correct the damping force without such difficulty. A liquid chamber 26 is provided in a main body 17 of a steering damper 10, and its inside is partitioned into a right liquid chamber 27 and a left liquid chamber 28 by a rotatable partition wall 30 integral with a shaft 23 coaxial with a steering shaft 14. The both liquid chambers are connected with each other by a liquid passage 33, and a control valve 31 is provided in the middle of the passage such that the damping force is variable. A control device 32 drive-controls the control valve 31 in correspondence with a turning angle speed of the shaft 23 and the partition wall 30, thereby controls the damping force, and corrects the damping force based on intake temperature information detected by an intake temperature sensor 34.
Patent CA-2396230-C (CA)
Title: Method for producing a cosmetically applicable marine mud extract and product containing said marine mud extract
Inventor: GOJNY PAUL
IPC: A61K35/02
Filed: 2001-01-03
Granted: 2011-06-28
Abstract: The invention relates to a method for producing extracts from mud. The aim of the invention to increase the share of the cosmetically and balneologically active substances from the mud. To this end, paraffinum subliquidum, ethanol, dimethicone, a water/ethanol mixture and a mixture from water/ethanol/glycerol/propylene glycol is used as the extracting agent. The mixture is extracted while stirred either for 24 to 30 hours at room temperature or for 1 to 3 hours at 50 °C to 70 °C and is then filtered. The filtrate contains a share of active substances from the marine mud.
Patent CA-2406719-C (CA)
Title: Monitoring system and method for networked data processing installations
Inventor: ROWDEN NEVILLE
IPC: B61L27/00
Filed: 2000-12-30
Granted: 2007-01-30
Abstract: The invention relates to a monitoring system of networked data processing installations (A, B, C, D, E) which has tasks to accomplish relating to security, in particular in the railway engineering field. Said system accomplishes said monitoring task in the form of a subprocess of all the data processing installations (A, B, C, D, E). To this end, each data processing installation takes over tasks during the monitoring of the other data processing installations (A, B, C, D, E). Significant conclusions can be drawn relating to individual data processing installations and to the local and global processes and the data of said individual data processing installations (A, B, C, D, E), based on status data (ZA, ZB, ZC, ZD, ZE), which provides information about local and global processes and the data of the individual data processing installations. The status data results from periodic self-tests (UA, UB, UC, UD, UE) carried out by the data processing installations (A, B, C, D, E) and is output on the network in a visible manner, for all the data processing installations (A, B, C, D, E). The data processing installation which is responsible for carrying out the monitoring can thus, as a result of its own, or of the indirect monitoring of the other data processing installations, identify errors in the data processing installation to be monitored and can initiate corrective measures.
Patent CA-2407416-C (CA)
Inventor: MAHANEY PAIGE ERIN
IPC: C07D403/12
Filed: 2001-04-25
Granted: 2006-07-18
Abstract: Para-alkynyl phenyl heteroaromatic amides which are active as glucokinase activators to increase insulin secretion which makes them useful for treating type II diabetes.
Patent CA-2410675-C (CA)
Title: Medicament-loaded transdermal reservoir and method for its formation
Inventor: BERNHARD MICHAEL I
IPC: A61M37/00
Filed: 2001-05-30
Granted: 2013-02-05
Abstract: A transdermal reservoir (10) and a method for loading a material includes providing a reservoir including a backing (12) with an interior surface (14) comprising a bibulous reservoir (18) having a patient contact surface (20) disposed on the interior surface (14). The method includes providing a closure (24) sized to engage the backing (12) to form a releasable seal to isolate the bibulous reservoir (18) from the ambient environment. The closure (24) has an inside surface (28) with an absorbent material disposed thereon such that the absorbent material is positioned in intimate contact with the bilulous reservoir (18) when the closure (24) engages the backing (12). The method includes applying an aliquot of a material to the absorbent material, placing the closure (24) on the backing (12) which puts the absorbent material in intimate contact with the bilulous reservoir (18) and allowing the assembly sufficient time to allow the aliquot of material to be absorbed into the bibulous reservoir (18).
Patent CA-2411680-C (CA)
Title: Branched copolymers based on unsaturated nitriles and conjugated dienes
Inventor: MAGG HANS
IPC: C08F236/12
Filed: 2001-05-25
Granted: 2011-07-26
Abstract: The present invention relates to branched copolymers based on unsaturated nitriles and conjugated dienes which are characterized in that the content of bonded unsaturated nitrile is 15 to 50 wt.%, the Mooney viscosity ranges from 15 to 150 MU [ML 1+ 4/100°C], the chain branching ranges from 0 to 20° (determined by the .DELTA..delta.B value) and the solubility is >=85 wt.% (measured in methyl ethyl ketone at 20°C). The copolymers according to the invention can be used for the preparation of hydrogenated copolymers based on unsaturated nitriles and conjugated dienes (HNBRs) for the production of all kinds of mouldings by the injection moulding or extrusion process and for improving the flowability of elastomers.
Patent CA-2413640-C (CA)
Inventor: WORTHING RICHARD ROY JR
IPC: C23C10/58
Filed: 2002-12-05
Granted: 2008-08-19
Abstract: A process of rejuvenating a diffusion aluminide coating (20) on a component (10). The rejuvenation process involves treating the coating (20) with an aqueous solution of nitric acid and phosphoric acid until at least part of the additive layer (22) of the coating (20) has been removed, but the diffusion zone (24) underlying the additive layer (22) remains. The exposed surface of the component (10) is then re- aluminized to deposit additional aluminum to build up the additive layer (22) to a desired thickness. The process is particularly applicable to a diffusion aluminide coating (20) that has been deposited on a component (10) to have an excessively thick additive layer (22), and prior to the component (10) being returned to service.
Patent CA-2414316-C (CA)
Inventor: LILJA JAN
IPC: G01N33/72
Filed: 2001-06-25
Granted: 2011-02-15
Abstract: The present invention concerns a method for hemoglobin determination which comprises the steps of introducing a sample of undiluted whole blood by capillary action into a disposable microcuvette having at least one cavity for receiving the sample. The cavity includes a dry essentially non-hygroscopic hemolysing agent, which is dissolved by the blood, hemolyses the red blood cells and releases the haemoglobin contained in the blood cells. A first absorption measurement at a wavelength range 490-520 nm is then performed directly on the sample in the microcuvette, and a second absorption measurement is performed to compensate for background interference.
Patent CA-2424449-C (CA)
Inventor: WASCHGLER MICHAEL
IPC: E05B13/00
Filed: 2003-03-31
Granted: 2011-01-25
Abstract: An operating device for doors, windows, etc. comprises a rosette (20) for holding a rotating handle (10) whose head (12) contains a lock cylinder (18) with an axially displaceable locking bolt (44) that is axially spring-loaded and automatically assumes an engaging position at a defined angle of rotation of the handle (10) by sliding over a stepped locking sleeve (30) of the rosette (20). The lock cylinder (18) has a core (40) with a radial opening (50) in a non- rotating wall (58) for controlled movement of a spindle (48) that radially extends from the locking bolt (44) which engages the locking sleeve in defined angular positions of the handle (10). The opening (50) extends over a peripheral angle of e.g. 180° to 220°, and is a con- toured window having a lower flat segment (52), a depression (54) and a steeper segment (flank 56). On top, two straight edge sections (62, 66) run out at a vertical intermediate edge (58) above the depression (54), with lateral edges of the opening (50) forming stops for the spindle (48). If the key S is in the cylinder (18), pivoting the handle (10) from a horizontal position into an upward position (12 o'clock) requires two-hand operation. As the handle (10) is turned down into a transverse position (3 o'clock or 9 o'clock), the locking bolt (44) engages behind a tangential stop (68) under spring load, whether or not the key (S) is in the lock cylinder (18).
Patent CA-2424948-C (CA)
Inventor: WILDE PETER
IPC: D21H13/50
Filed: 2003-04-10
Granted: 2011-03-22
Abstract: This invention relates to electrode substrates for electrochemical cells, particularly low-temperature fuel cells, and processes for their production. Low-cost carbon fiber paper structures are used as precursor for preparation of an all-carbon product that has a high electric conductivity and porosity and be processed in a continuous reel-to- reel mode. These paper materials are further impregnated and processed to adjust the final product properties. This all-carbon electrode substrate is not brittle thereby avoiding the main disadvantage of the prior art.
Patent CA-2432494-C (CA)
Title: Vehicle dynamics prediction system and method
Inventor: COLE COLIN ROBERT
IPC: G05B13/04
Filed: 2001-12-20
Granted: 2009-07-14
Abstract: A vehicle dynamics prediction system for providing prediction of vehicle velocity for a predetermined future time period. The predictions utilise future vehicle control setting anticipated for the time period. An artificial intelligence database coupled to a processor that utilises weighted values for neural network models representing dynamic performance of the vehicle forms part of the vehicle dynamics prediction system.
Patent CA-2432816-C (CA)
Title: Easy-fit heat screening device for connecting a cooling pipe and a through-hole formed in a nozzle support ring of a gas turbine
Inventor: PECCHIOLI MARIO
IPC: F01D25/12
Filed: 2003-06-19
Granted: 2010-11-09
Abstract: An easy-fit heat screening device (110) for connecting a cooling pipe (112) and a through-hole (114) formed in a nozzle support ring (116) of a gas turbine, of the type comprising a tubular structure (118) which has an external diameter smaller than a diameter of the through-hole (114) and into which the cooling pipe (112) extends; this tubular structure (118) has at the top a shaped annular end (126) which is inserted inside a groove (130) formed in the through-hole (114).
Patent CA-2433987-C (CA)
Title: Brush assembly distribution apparatus
Inventor: RENNECKER DAVID B
IPC: A47L11/34
Filed: 2003-06-27
Granted: 2007-08-21
Abstract: A floor-scrubbing machine is provided having a main body and a cleaning fluid delivery system. At beast one rotatable brush having a brush body and bristles extending from the brush body is included. The brush is carried by the main body whereby the bristles of the brush engage the floor being scrubbed. A fluid distributor is provided to distribute cleaning fluid supplied to the fluid distributor to the brush. The brush defines a recess having a sidewall and at least one opening formed in the sidewall for distributing the cleaning solution radially outward.
Patent CA-2437170-C (CA)
Title: Compositions suitable for the treatment of hair comprising chelants and methods for reducing oxidative hair damage
Inventor: OLSHAVSKY MICHAEL ANDREW
IPC: A61K8/41
Filed: 2002-03-19
Granted: 2009-10-27
Abstract: The present invention relates to hair care compositions comprising an oxidizing agent and chelants having a log KCuL/log KCaL ratio calculated at pH  10 of at least 3.20 wherein log KCuL is the common logarithm of the Conditional Stability Constant of said chelant with Cu2+ and log KCaL is the common logarithm of the Conditional Stability Constant of said chelant with Ca2+. Suitable chelants are diamine-N,N'-dipolyacids or monoamine monoamide-N,N'-dipolyacids. The compositions according to the present invention contribute to reducing the oxidative damage sustained by a keratinous fiber such as hair during bleaching, dyeing, perming or other oxidative treatments.  Especially preferred diamine dipolyacid is ethylenediamine-N,N'-disuccinic acid (EDDS).
Patent CA-2440824-C (CA)
Inventor: ARIAS LOPEZ JUAN-LUIS
IPC: A23L13/00
Filed: 2002-03-12
Granted: 2009-11-17
Abstract: Film (3) for wrapping food products, made of an edible or inedible material, curved onto itself along a longitudinal axis to form a cylinder in which the lateral edges of the film are overlapping to a certain extent, shirred or wrinkled in the manner of an accordion to form folds perpendicular to the axis of said cylinder, that can have an internal support in the form of a tube (1) of a stiff material (1), and which can be externally coated by a separation sheet (5) and an also shirred tubular net (6), and the method for manufacturing it.