baber/WOPTO huggingface dataset:
Patent CA-2149882-A1 (CA)
Title: Rxr homodimer formation and bridged bicyclic aromatic compounds and their use in modulating gene expression
Inventor: PFAHL MAGNUS
IPC: A61P3/02
Filed: 1993-11-24
Abstract: The invention provides a method of screening a substance for the ability to affect the formation of a retinoid X receptor homodimer comprising combining the substance and a solution containing retinoid X receptors and determining the presence of homodimer formation. The screening method can be used to determine compounds which selectively activate homodimer formation and heterodimer formation. Also provided is a method of screening a substance for an effect on a retinoid X receptor homodimer's ability to bind DNA  comprising combining the substance with the homodimer and determining the effect of the compound on the homodimer's ability to bind DNA. Finally, the invention provides methods of activating retinoid X receptor homodimer formation. Bridged bicyclic aromatic compounds are provided having structure (I); wherein R1, R2, R3, R4, R5 and n are as defined herein. The compounds are useful for modulating gene expression of retinoic acid receptors, vitamin D receptors and thyroid receptors. Pharmaceutical compositions and methods for modulating gene expression are provided as well.
Patent CA-2150948-A1 (CA)
Title: Process for the preparation of alpha-aryl-gamma-butyrolactones
Inventor: SHEPHERD ROBIN GERALD
IPC: C07D315/00
Filed: 1993-11-25
Abstract: A process for preparing a lactone of general formula (I), where R is an optionally substituted phenyl group or an optionally substituted mono- or bicyclic heteroaryl radical which process comprises reacting an anion of a malonate of formula (II) with an ethylene compound of formula (III) Y-CH2-CH2OZ, to give a compound of formula (IV) and hydrolysing the compound of formula (IV) to give a lactone of formula (I). The lactones are of use as intermediates for preparing 5-HT1A binding agents.
Patent CA-2151264-A1 (CA)
Title: Negative working, peel developable, single sheet color proofing system having a crosslined layer containing a polymer with phenolic moieties
Inventor: WILCZAK WOJCIECH A
IPC: G03F7/095
Filed: 1994-01-19
Abstract: In the present invention, one produces a negative-acting color proofing element comprising sequentially, a strippable cover sheet which is transparent to actinic radiation; a crosslinked layer containing a polymer having a phenolic groups; a color layer, containing a colorant, a polymeric binder, a polymerizable monomer and, optionally, a photoinitiator, a photoadhering layer, containing a linear photosensitive polymer containing ethylenically unsaturated, free-radical polymerizable groups and having a molecular weight greater than 3,000, a polymerizable monomer, and, optionally, a free radical photoinitiator; a thermoplastic adhesive layer; and a receiver sheet, at least one of the color layer and the photoadhering layer containing the photoiniator.
Patent CA-2154470-A1 (CA)
Title: Anterior cervical plating system
Inventor: LOWERY GARY
IPC: A61B17/58
Filed: 1994-01-24
Abstract: An anterior cervical plating system includes an elongated plate (20) having pairs of screw bores (27) at opposite ends (24, 24) of the plate, and bone screw slots (50) in the middle bridge portion (25) of the plate. A single locking screw (40) is provided at each end of the plate which engages the heads (32) of the bone screws (30) trapped within recesses (28) of the plate. A drill and tap guide assembly (100) is also disclosed which can be mounted on the fixation plate (20) for accurately drilling and tapping screw holes into the vertebra The drill and tap guide assembly (100) includes an assembly support (101) which is engaged to the plate (20) by way of a positioning screw (105) and cross pins (106) mounting the positioning screw (105) to the guide body (110).
Patent CA-2154750-A1 (CA)
Title: Compositions and methods for temporarily coloring hair using solubilized melanin
Inventor: WOLFRAM LESSEK J
IPC: A61Q5/06
Filed: 1993-11-17
Abstract: Compositions comprising using solubilized melanin and at least one water soluble or water dispersible cationic material, which composition is suitable for user as a temporary and a process for temporarily coloring hair using such compositions.
Patent CA-2155538-A1 (CA)
Inventor: KING PATRICK D
IPC: B22D41/40
Filed: 1993-08-04
Abstract: A sliding gate valve (5) has a frame with a sliding carrier (11) within the frame, a stationary plate secured at an upper portion of the valve and a slide gate plate (16) secured at a lower portion of the valve. In one embodiment a spring plate (12) is provided with beam springs mounted in cantilever fashion with their end portions orientated in surrounding relationship to a teeming opening of the valve. In addition, a cluster (28) of such springs is provided at a shut-off portion of the slide plate which underlies the teeming opening to the vessel in the shut-off position. This mounting may be reversed with the springs secured in cantilever fashion to the carrier and the spring plate eliminated, while the springs bear directly on the underside of the metal encased refractories (19). The spring plate can have the cantilever springs mounted on both sides and is positioned between the slide gate plate and the carrier. This results cutting the spring rate in half. By providing double springing, such as reversely folding a pair of springs upon each other, also cuts the spring rate in half. With spring pairs mounted on each other on one side of the spring plate and a single spring on the other side, the spring rate is cut to one-third of that of a single spring. To cut the spring rate to one fourth, doubled springs are used on both faces of the spring plate.
Patent CA-2157969-A1 (CA)
Inventor: BAKER ROBERT GROVER
IPC: G06V30/10
Filed: 1995-09-11
Abstract: A method and computer implementation are disclosed for correcting skew and shiftwhich may occur as the image on a document or other field is scanned with line scanning apparatus. By selecting scans, lines are logically overlaid upon a memory map of the scanned image and a best-fit line is calculated through left-most image points near the left ends of the lines. The best-fit line substantially defines the left margin. The angle which complements the angle between the overlay lines and the best-fit line is calculated and the image map is rotated in storage, aligning the image with scanner's x-axis and y-axis. The method may be started while scanning is still in progress and the last portion of the image may be rotated according to the invention as it is being stored. The left margin is more accurately found by expanding the search for left-most pixels using search areas around the fit originally found left-most points. The best-fit line is further refined by calculating a standard deviation of each left-most point from the best-fit line and taking a new best-fit line through those points that deviate by less than for example two sigma from the original best-fit line.
Patent CA-2161156-A1 (CA)
Title: Process for the preparation of fatty acid-esterified propoxylated glycerin
Inventor: COOPER CHARLES F
IPC: C07C67/03
Filed: 1995-10-23
Abstract: A convenient method of obtaining useful esterified propoxylated glycerin fat substitutes from readily available triglycerides such as fats and oil is provided wherein a triglyceride is reacted  with a propoxylated glycerin under conditionseffective to remove glycerin during such reaction.
Patent CA-2161231-A1 (CA)
Title: Molecular sieve layers and processes for their manufacture
Inventor: DECKMAN HARRY WILLIAM
IPC: C01B39/00
Filed: 1994-04-25
Abstract: Layers comprising a molecular sieve layer on a porous or non-porous support, having uniform properties and allowing high flux are prepared from colloidal solutions of zeolite or other molecular sieve precursors (particle size less than 100 nm), by deposition, e.g., by spin or dipcoating, or by in situ crystallization.
Patent CA-2163110-A1 (CA)
Title: Container with multiple chambers, to package components separately prior to use in admixture
Inventor: RICHTER HANS-UWE
IPC: A61K49/00
Filed: 1994-05-19
Abstract: The invention provides especially a package for accommo-dating a product having at least two components, which package has at least two self-contained chambers in which the individual components of the product can be stored in such a manner that they are hermetically separated from one another. The individual chambers are connected together in such a manner that they can be separated from one another only by destroying at least one chamber wall. The end regions of the chamber walls are in the form of a common closure for the individual chambers such that the individual chambers can only be opened simultaneously. in an especially preferred form of the invention, the package com-prises at least one folded carton (11) having essentially a front and a back wall side walls, bottom flaps and top flaps, inside which carton there are arranged in a fixed manner at least two tube-like inner sachets (45, 46) each of which accommodates one of the components, directly and which represent the chambers for the individual components, and the top end regions (48) of which that project out of the inside of the folded carton (11) form the common closure (49) after the inner sachets have been filled sep-arately.
Patent CA-2165434-A1 (CA)
Inventor: MARTIN DONALD LEWIS MAUNSELL
IPC: G02B27/22
Filed: 1994-06-06
Abstract: An arrangement is provided for use in three-dimensional imagery, which includes a grid formation formed of a plurality of spaced apart slats located between a viewer and imagery. The slats are laterally spaced apart one from the other and have dimensions of width, length and depth. Means are provided to transpose the slats and spaces or slots therebetween, vertically and laterally.
Patent CA-2169006-A1 (CA)
Title: Photographic Printer
Inventor: NAKAOKA NOBUAKI
IPC: G03B27/32
Filed: 1996-02-07
Abstract: A photographic printer has an exposure station for exposing and printing images of photographic film on printing paper, a cutter for cutting the photographic film, after a printing process, to film pieces of a length having a predetermined number of frames, and cartridges for collecting the film pieces as sorted into separate orders. Each cartridge stores a group of film pieces stacked one upon the other, and transports the group of film pieces to a film outlet.
Patent CA-2171812-A1 (CA)
Title: Note pad with single hole or pair of slits and writing instrument combination
Inventor: ZOLAND MARTIN
IPC: B43K25/02
Filed: 1996-03-13
Abstract: A combination of a writing instrument and a note pad or calendar wherein the writing instrument can be easily attached to and removed from the note pad or calendar.  A through-hole in the note pad or calendar is adapted to receive a pocket clip typically found on many conventional pens.  Preferably, the clip has an upwardly curved end to facilitate insertion of the clip into the hole, especially where the note pad or calendar includes a number of sheets of paper requiring that the hole pass through each of the sheets.  In a preferred embodiment, the through-hole is located near an edge of the note pad or calendar.  Thus, a pen or other writing instrument can be secured to the note pad or calendar by inserting the clip through the hole.
Patent CA-2171895-A1 (CA)
Title: Veneer Hoisting Apparatus
Inventor: ITO AKIRA
IPC: B65G61/00
Filed: 1996-03-15
Abstract: A veneer hoisting apparatus in which even a top veneer of piled veneers is inclined, a piercing unit is adapted to the inclination to pierce and hoist the veneer by piercing members. The veneer hoisting apparatus comprises: a piercing unit with a sharp piercing member; an elevating member for vertically moving the piercing unit fixed thereto; a device for supporting the elevating member, the device having an angle adjusting mechanism for adjusting an angle between the piercing unit and the top veneer when the piercing member contacts the top veneer; and a controller for controlling motion of the elevating member.
Patent CA-2173557-A1 (CA)
Inventor: YANO NOBUYOSHI
IPC: G08B13/24
Filed: 1996-04-04
Abstract: A magnetic marker which comprises a flexible organic polymer substrate having an anisotropic thermal shrinking property and a soft magnetic thin film having uniaxial magnetic anisotropy.  The angle formed between the direction in which the organic polymer substrate has the highest degree of thermal shrinkage and the direction of magnetic easy axis in the soft magnetic thin film is in the range from 50° to 90°.  The marker is a thin film of a simple structure, yet exhibits satisfactory magnetic characteristics.  A roll having a plurality of magnetic markers, each comprising an organic polymer substrate and a soft magnetic thin film formed transversely on the surface, can be manufactured by a process relying upon the combination of (i) a roll coater method and (ii) a sputtering technique.  In the process, the organic polymer substrate is set and continuously transported such that the direction in which the organic polymer substrate experiences the highest degree of thermal shrinkage is not greater than 40° with respect to the direction of its travel.  Furthermore, the thickness of the soft magnetic thin film that is deposited per unit of the cathode as the result of a single pass of the organic polymer substrate over the cathode does not exceed 0.4 µm.  The process is capable of continuous production of magnetic markers having satisfactory magnetic characteristics and advantageously enables easy manufacture of a roll having a plurality of such magnetic markers arranged transversely thereon.
Patent CA-2176281-A1 (CA)
Inventor: SURINA MICHAEL
IPC: B21D5/08
Filed: 1996-05-10
Abstract: A roll forming apparatus having a plurality of roller die stands, through which a web workpiece is passed, for progressively forming  edge flange bends and for subsequently forming  side flange bends between the side flanges and the web, and having side flange corner forming upper dies which are mounted on angled spindles, and  fit around the edge flanges and enter into the side flange corners, and further having side flange control rolls engaging the outer surface of the side flanges, the control rolls being movably mounted for tilting inwardly or outwardly, so as to produce a greater or lesser degree of bend between the side flanges and the web.
Patent CA-2176474-A1 (CA)
Title: Viracidal, bactericidal and spermicidal vaginal suppository
Inventor: FORD LARRY C
IPC: A61K35/747
Filed: 1994-12-02
Abstract: A vaginal suppository or other type of vaginal passary such as cream, foam or ointment, which contains as its active ingredients at least one pharmaceutically acceptable, topically safe antimicrobial agent, such as an agent selected from the group of benzalkonium chloride, cetylpyridinium chloride, chlorhexidine gluconate and povidone iodine, imidiazolidinyl urea and diazolidinyl urea and a viable colony of micro-encapsulated lactobacilli bacteria. The viable lactobacilli are included in the suppository in micro encapsulated form, which protects the bacteria during storage of the suppository from the action of the bacteriocidal agent. When exposed to the vaginal milieu the micro encapsulation breaks down sufficiently to release the lactobacilli bacteria. The lactobacilli bacteria serve to maintain or re-establish a healthy lactobacilli based flora on the vaginal wall, and excrete hydrogen peroxide and other bactericidins which suppress abnormal flora conditions that promote infections,
Patent CA-2176511-A1 (CA)
Inventor: SEGUIN MARIE-CHRISTINE
IPC: A61K8/00
Filed: 1995-09-29
Abstract: Composé à base de silicium de formule générale: a) dans laquelle A, B, C, D sont des radicaux différents de OH liés à Si par des liaisons covalentes; deux ou trois de ces liaisons avec Si sont des liaisons du type Si-O-C, Si-S-C ou Si-N-C, hydrolysables in vivo avec formation de liaisons Si-OH biologiquement actives, notamment au contact de tissus vivants, les liaisons A et D de la formule b) étant toujours hydrolysables; au moins une des liaisons hydrolysables corresponds à un radical acyloxy, aryloxy ou vinyloxy; au moins un des composés obtenus après hydrolyse desdites liaisons hydrolysables est un stabilisant; et les liaisons non hydrolysables sont du type Si-C et correspondent à des radicaux hydrocarbonés ou fluorocarbonés pour lesquels Si n'est pas directement lié à un noyau phényle.
Patent CA-2178744-A1 (CA)
Title: Restraining devices
Inventor: TRETHEWEY REGINALD
IPC: A01K15/04
Filed: 1994-12-13
Abstract: A bail assembly (10) including bail means (18, 19) moveable between operative engaged positions and a disengaged position; bail actuating (25) means for quickly moving the bail means (18, 19) between the operative engaged positions and the disengaged position, and holding means (35) for holding the bail means (18, 19) at any selected operative engaged position. Preferably the holding means (35) is a selectively releasable self locking hydraulic cylinder assembly which includes adjustable holding means (35), a locking chamber (36) associated with the adjustable holding means which may be filled to lock the adjustable holding means; control means (44) for controlling flow of fluid to and from the locking chamber, and actuating means for selectively actuating the control means (46).
Patent CA-2179800-A1 (CA)
Inventor: AGRAWAL RAKESH
IPC: C01B21/04
Filed: 1996-06-24
Abstract: A process for separating a feed gas mixture into a more strongly adsorbable component and a less strongly adsorbable component in a plurality of adsorbent beds containing an adsorbent selective for the more strongly adsorbable component using cocurrent depressurization to provide purge gas and pressurization by product end to product end pressure equalization between beds simultaneous with cocurrent ambient and elevated pressure feed pressurization, and countercurrent evacuation. Oxygen product can be recovered from air at high recovery and adsorbent productivity levels using the process.
Patent CA-2180323-A1 (CA)
Inventor: SUGA HITOSHI
IPC: F16F7/12
Filed: 1996-07-02
Abstract: A collision energy absorbing structure of an automobile is provided with an energy absorbing space between an inner panel of a vehicle structure member and an interior trim material covering the inner panel in the inward thereof and has a grid-like non-metal energy absorber (10) disposed within the energy absorbing space, the energy absorber (10) including one or a plurality of longitudinal ribs (32) and a plurality of lateral ribs (34). Each longitudinal rib (32) of the energy absorber has notches (36) on the inward side confronting the interior trim material directed toward a junction (33) where each longitudinal rib intersects each lateral rib and joined together.
Patent CA-2180660-A1 (CA)
Title: Novel piperidine derivatives with paf antagonist activity
Inventor: CARCELLER ELENA
IPC: A61P17/00
Filed: 1995-09-05
Abstract: Compounds of general formula (I) and their salts and solvates are PAF antagonists and as such are useful in the treatment of various diseases or disorders mediated by PAF. Pharmaceutical compositions including these compounds and processes for their preparation are also provided.
Patent CA-2181009-A1 (CA)
Title: Multiple owner resource management
Inventor: ERB PAUL
IPC: G06F9/46
Filed: 1996-07-11
Abstract: A method of management of resources in a multiple process system providing a list of resource owner identities, storing in an owner list the identity of at least one process with a resource which the at least one process has a right to operate, and allowing only a process listed with a resource to use the resource.
Patent CA-2181028-A1 (CA)
Inventor: SCHAPIRA JOSEPH
IPC: A01N25/14
Filed: 1996-07-11
Abstract: The invention relates to a new solid storage and marketing presentation for phytosanitary compositions based on any active substance which is little soluble in water or insoluble in water and solid at ambient temperature, these active substances are especially selected from herbicides presenting the said features: these herbicides comprise bromoxynil, ioxynil and their esters as well as dinitroanilines, especially butraline, pendimethaline, flumetraline and oryzalin.           It is in the form of flake based on a film-forming material which is water-soluble and brittle after drying, and throughout which are dispersed especially the particles of active material.           This solid storage and marketing presentation may be prepared by means of an installation comprising a rotating drying drum (1) on which a thin layer of a dispersion solution of particles of active substance in an aqueous solution of a film-forming material which is brittle at the dry state is applied.            The parties of the surface of the drum on which is applied the dispersion (D) travel through the heated part or zone of the chamber (2) at a speed such that the dispersion is dried, shrinks and becomes detached fromthe surface of the drum (1) in forming flakes (P).
Patent CA-2181038-A1 (CA)
Title: Foamable resin composition, foam produced therefrom, and process for producing the foam
Inventor: ANDO HIROSHI
IPC: C08J9/02
Filed: 1995-11-15
Abstract: A foaming resin composition consisting essentially of (A) an organic compound having a carbon-carbon double bond, (B) a compound having an SiH group, and (C) a compound having an OH group is foamed and cured at room temperature or under heat at relatively low temperatures, to obtain hard, semi-hard or soft plastic foam having good weather resistance and good compatibility with coating compositions and adhesives.
Patent CA-2181472-A1 (CA)
Inventor: FEINGOLD VLADIMIR
IPC: A61F9/013
Filed: 1995-11-17
Abstract: La présente invention concerne un système d'injection (12) de lentille intraoculaire comportant un dispositif d'injection et une cartouche (14). La cartouche (14) comporte une partie (38) contenant la lentille et une partie (40) formant un manchon extérieur. L'invention concerne également un procédé de préchargement du système d'injection (12), notamment de la cartouche (14), destiné à réduire la quantité d'emballage, à prévenir la détérioration de la lentille intraoculaire au cours de l'emballage et de l'expédition, à permettre de passer à l'autoclave la cartouche d'injection préchargée sous forme unitaire, et à supprimer l'étape de chargement de la cartouche avec la lentille intraoculaire par l'utilisateur final de façon à éviter les détériorations qui peuvent se produire au cours de cette étape.
Patent CA-2182174-A1 (CA)
Title: Muscle-powered watercraft
Inventor: PROVERBIO RODOLPHE
IPC: B63H1/36
Filed: 1994-12-05
Abstract: A watercraft including flotation (1) and propulsion members, which propulsion members are two blades (2 and 3) hinged to a float. The floatability factor of the float is such that the volume of water displaced in the submerged position weighs the same as or up to twice as much as the laden craft, whereby, when a pitching motion is imparted to the craft, it moves sinusoidally in and out of the water and the blades (2 and 3) swing back and forth about their respective hinges between abutments, thus urging the craft forwards.