baber/WOPTO huggingface dataset:
Patent EP-1436316-B1 (EP)
Inventor: LEBOWITZ JONATHAN H
IPC: C07K14/65
Filed: 2002-04-30
Granted: 2008-01-23
Abstract: Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells and methods relation to the practice of the invention are also provided.
Patent EP-1413075-B1 (EP)
Inventor: RUDOLPH DIETMAR
IPC: H04H20/49
Filed: 2002-04-10
Granted: 2009-12-02
Abstract: A method for digital transmission using an AM transmitter includes operating an output stage of the AM transmitter in a linear mode and correcting the supply voltage of the output stage in the linear mode as a function of an instantaneous drive so as to improve efficiency. The correcting is performed by operating the modulator of the AM transmitter as a switched-mode power supply unit so as to deliver a corrected supply voltage to the output stage, and scanning an envelope of a complex modulated data signal so as to control the correcting. A time constant during the scanning of the envelope enables immediate following of a rise in the envelope. The complex modulated data signal is delayed after the scanning so as to perform the correcting during the delay and prevent an overdriving of the output stage.
Patent EP-1406829-B1 (EP)
Inventor: BRESSOUD PATRICK
IPC: B29C48/355
Filed: 2002-06-06
Granted: 2006-04-05
Abstract: The tracked drive device particularly protected by its frame or hood as well as by protective plates, so as to prevent any accidental insertion of a finger or any other part of the human body between the track elements. The arrangement makes access to the track, for replacement or maintenance, particularly difficult. The invention provides a pivoting construction of the driving device, whereby the driving mechanisms become easily accessible, thus facilitating track change.
Patent EP-1374624-B1 (EP)
Inventor: SAMBIN MARCO
IPC: H04W64/00
Filed: 2002-03-30
Granted: 2010-02-10
Abstract: In cellular telephony mobile equipment location-based services data transmission an application carries out measures on Base Transceiver Stations or associated cells by detecting, storing and transmitting respective information to a remote Service Center by means of messages, and a processing system, applying calculation procedures and a Base Transceiver Stations geographic position database, computes data associated with the location-based services. In the application at least one message is generated containing a set of data in compressed format, the set of data being selected from a set comprising specific data on each single message, specific data on the message set, specific data on measurements and specific data on the cells monitored by the mobile equipment. The dimensions of the specific data on the measurements generated in compressed format depend on results of the measurements made at a current instant and those obtained at an earlier time.
Patent EP-1414410-B1 (EP)
Inventor: GRENIER PASCAL
IPC: A61K9/14
Filed: 2002-08-09
Granted: 2009-02-04
Abstract: Nanoparticles and nanoparticle formulations or suspensions are provided which comprise a fibrate and vitamin E TPGS. The nanoparticles may have a mean diameter, measured by photon correlation spectroscopy, in the range of from about 100 nm to about 900 nm. Pharmaceutical formulations and uses of such compositions are also provided.
Patent EP-1426385-B1 (EP)
Inventor: SUN XIULI
IPC: C08F4/60
Filed: 2002-06-17
Granted: 2012-08-22
Abstract: La présente invention a trait à des catalyseurs et/ou des systèmes catalytiques utiles pour la polymérisation ou la copolymérisation d'α-oléfine. Lesdits catalyseurs contiennent de l'oxygène, du soufre, du sélénium ou de l'azote ou des composés de métaux de transitions contenant du phosphore comportant le motif de squelette correspondant à la formule (I), dans laquelle: M est un élément appartenant au groupe 3-11 du tableau périodique; A, D et E représentent chacun un groupe de coordination contenant un atome d'oxygène, de soufre, de sélénium, d'azote ou de phosphore.
Patent EP-1421985-B1 (EP)
Inventor: OHYA TOMOAKI
IPC: B01D39/20
Filed: 2002-08-08
Granted: 2012-05-23
Abstract: A heat-resistant filter which comprises a heat-resistant organic fiber substrate and, fixed thereto, a resin composition comprising an alkaline substance. The filter is reduced in the degree of the decrease in tensile strength and folding endurance, even after it is used under a high temperature condition, and is less prone to the failure of the material thereof even when it is used at a high temperature, and thus is capable of achieving a useful life of a long period of time.
Patent EP-1421133-B1 (EP)
Inventor: WHITE JERRY E
IPC: C08L23/06
Filed: 2002-07-16
Granted: 2007-07-04
Abstract: The present invention provides thermoplastic hydroxy-functional polyesters. The polyesters have at least 10 sequential units, wherein the sequential units consist of units selected from units represented by the following formula (1) and units represented by the following formula (2); Wherein each of R<SUP>1 </SUP>independently represents hydrogen or a substituted or unsubstituted homoalkyl or heteroalkyl group; each of R<SUP>2 </SUP>independently represents hydrogen or a substituted or unsubstituted homoalkyl or heteroalkyl group; each of R<SUP>3 </SUP>independently represents hydrogen or a substituted or unsubstituted homoalkyl or heteroalkyl group; Each of R<SUP>4 </SUP>independently represents a substituted or unsubstituted homoalkyl or heteroalkyl group; and said moiety having no fewer than 1 unit represented by formula (1) and no fewer than 1 unit represented by formula (2). The present invention further provides processes for making hydroxyfunctional polyesters, such as polymerizing epoxidized fatty acids in the presence of an onium salt, and compositions and articles that include or are derived from the hydroxyfuntional polyesters
Patent EP-1546376-B1 (EP)
Inventor: YASUNO HIDEYUKI
IPC: C12Q1/68
Filed: 2002-09-30
Granted: 2008-11-12
Abstract: Oligonucleotides for genotyping the thymidylate synthase gene are provided. The number of tandem repeats in the promoter region of the thymidylate synthase gene can be identified based on the hybridization of an oligonucleotide of the invention to the genomic DNA of a subject. Therefore, the genotype of the thymidylate synthase gene can be identified based on the number of tandem repeats. The genotype relates to the responsiveness of a subject towards an antitumor agent.
Patent EP-1456009-B1 (EP)
Inventor: WILLIAMS JALI
IPC: B29L31/48
Filed: 2002-09-06
Granted: 2006-07-12
Abstract: Cette invention se rapporte à la production d'articles élastomères, tels que des gants en élastomère, qui peuvent facilement être démoulés, qui offrent de bonnes caractéristiques tactiles et de préhension et qui peuvent être exempts de poudres, sans traitement de surface ni halogénation. En général, ces articles élastomères comprennent une couche externe ultramince formée d'un polymère à base d'acrylique et d'une couche polymère de base coagulée sur la surface de la couche externe, qui forme la matrice primaire de l'article élastomère. La couche externe ultramince de ces articles peut avoir une épaisseur comprise entre 0,25 microns environ et 8,0 microns environ.
Patent EP-1535297-B1 (EP)
Inventor: JAHNES CHRISTOPHER V
IPC: G02B5/00
Filed: 2002-08-26
Granted: 2008-03-05
Abstract: A micro-electromechanical (MEM) RF switch provided with a deflectable membrane ( 60 ) activates a switch contact or plunger ( 40 ). The membrane incorporates interdigitated metal electrodes ( 70 ) which cause a stress gradient in the membrane when activated by way of a DC electric field. The stress gradient results in a predictable bending or displacement of the membrane ( 60 ), and is used to mechanically displace the switch contact ( 30 ). An RF gap area ( 25 ) located within the cavity ( 250 ) is totally segregated from the gaps ( 71 ) between the interdigitated metal electrodes ( 70 ). The membrane is electrostatically displaced in two opposing directions, thereby aiding to activate and deactivate the switch. The micro-electromechanical switch includes: a cavity ( 250 ); at least one conductive path ( 20 ) integral to a first surface bordering the cavity; a flexible membrane ( 60 ) parallel to the first surface bordering the cavity ( 250 ), the flexible membrane ( 60 ) having a plurality of actuating electrodes ( 70 ); and a plunger ( 40 ) attached to the flexible membrane ( 60 ) in a direction away from the actuating electrodes ( 70 ), the plunger ( 40 ) having a conductive surface that makes electric contact with the conductive paths, opening and closing the switch.
Patent EP-1418956-B1 (EP)
Inventor: LEFRANC OLIVIER
IPC: A61F2/82
Filed: 2002-07-29
Granted: 2005-06-29
Abstract: The invention concerns a metal object for medical or surgical use, such as a prosthesis, for example an endovascular prosthesis (called stent) for percutaneous transluminal coronary angioplasty, comprising a metal substrate whereof the surface is coated partly at least with a polysaccharide compound. The invention is characterised in that the polysaccharide compound is covalently bound, via a plurality of grafting arms, comprising each at least a silane unit, bound on one side to the metal substrate by an -O- metal bond, and on the other side, directly or indirectly, by a covalent -NH- bond, with the polysaccharide compound.
Patent EP-1434870-B1 (EP)
Inventor: BLEICHER KONRAD
IPC: C07C323/63
Filed: 2002-09-19
Granted: 2006-12-27
Abstract: The present invention relates to a new process for the preparation compounds of formula I wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3 </SUP>and n are as described in the description which process comprises reacting compounds of formula II wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, n and R<SUP>4 </SUP>are as described in the description, with a protease in an aqueous system containing an organic co-solvent. The compound of formula I are useful for the preparation of 1,5-benzothiazepines which are useful as enzyme inhibitors, such as protease, interleukin-1beta-converting enzyme, elastase or angiotensin converting enzyme, GPCR antagonists (cholecystokinin, angiotensin II receptor).
Patent EP-1430248-B1 (EP)
Inventor: VITEL JEAN-PIERRE
IPC: F16L23/02
Filed: 2002-09-23
Granted: 2005-08-17
Abstract: The invention relates to a joint that is used to connect two tubular elements comprising: a basic body (12) consisting of an end piece (26), which is used to house a spigot end (6), and a flange (20); a counterflange (14); a packing (16); and tightening means (52, 54) which are disposed between the flange (20) and the counterflange (14).  Said tightening means can move the counterflange (14) from an assembly position, in which the packing (16) is slack, to a clamping position, in which the packing (16) is clamped against the housing end piece (26).  The inventive joint also comprises temporary holding means (60) which are designed to hold the counterflange (14) in the assembly position thereof when a spigot end (6) is being inserted into the housing end piece (26).  The invention is suitable for use in the leakproof assembly of pipe elements which are used in drinking water distribution systems and sewage disposal systems.
Patent EP-1456540-B1 (EP)
Inventor: WEIGL MANFRED
IPC: F04B43/04
Filed: 2002-11-28
Granted: 2006-06-28
Abstract: A diaphragm pump includes a pressure sensor disposed in the housing thereof, and which is used as an expansion tank for protecting the pressure sensor. To avoid excess pressure on the pressure sensor, the pressure sensor membrane is directly disposed in the pump head, i.e., above the pump membrane of the diaphragm pump, such that the increase in volume of the reducing agent during the freezing of the reducing agent inside the diaphragm pump is detected by deflection of the pump membrane against the force of a spring, and the pressure sensor membrane is protected from damage.
Patent EP-1430576-B1 (EP)
Inventor: PINO ALESSANDRO
IPC: H01T13/32
Filed: 2002-09-25
Granted: 2008-01-16
Abstract: A spark plug comprises an electrically-insulating sleeve ( 12 ) extending along a central axis ( 14 ) of the plug, a first electrode ( 16 ) having a tip ( 20 ), an electrically-conducting shell ( 22 ), and a second electrode ( 26 ) mounted on the shell, the second electrode having a tip ( 28 ). The tips ( 20 and 28 ) have spark surfaces ( 30, 32 ) which define a spark gap ( 34 ) of the plug. The spark surfaces ( 30, 32 ) are inclined at different angles (theta1, theta2) relative to a plane ( 36, 38 ) extending normally of said central axis ( 14 ) of the plug so that said spark gap ( 34 ) varies in width along the length of the gap with the narrowest point (X1) of the gap being further from the connection between the second electrode ( 26 ) and the shell ( 22 ) than the other end of the gap.
Patent EP-1333319-B1 (EP)
Inventor: YASUDA SHOJI
IPC: G03C1/34
Filed: 2003-01-30
Granted: 2009-06-10
Abstract: Disclosed is a silver halide photographic light-sensitive material comprising at least one silver halide emulsion layer on a support, which contains a fluorine compound having two or more fluorinated alkyl groups having two or more carbon atoms and 11 or less fluorine atoms and having at least one of an anionic hydrophilic group and a nonionic hydrophilic group, and has a characteristic curve drawn in orthogonal coordinates of logarithm of light exposure (x-axis) and optical density (y-axis) using equal unit lengths for the both axes, on which gamma is 5.0 or more for the optical density range of 0.3-3.0. There is provided a silver halide photographic light-sensitive material that provides high sensitivity, high contrast, favorable half tone dot quality and superior storage stability. <IMAGE>
Patent EP-1342574-B1 (EP)
Inventor: PEICK HUBERT
IPC: B41F7/24
Filed: 2003-02-15
Granted: 2010-10-06
Abstract: The filtering system/device consists of a ring-band filtering system that has a filter band (28) that moves forward the saturation with dirt particles. The filter band may be transportable between the supply station (30) and the collection station (32). The filter band may be U-shaped with the lower peripheral region having a drum-like lining. The filter band may begin from below via a perforated support band (36) that may be in the form of an end-less band that may be transportable around rollers (38, 40, 42, 44) from the height of the lower, middle as well as upper region of the drum-like arrangement. The support band may be moved forward around two of the lower and two of the upper rollers.
Patent EP-1321275-B1 (EP)
Title: Thermoplastic resin injection molding machine
Inventor: SETA KUNIHITO
IPC: B29K101/12
Filed: 1999-12-20
Granted: 2009-11-11
Abstract: A thermoplastic resin injection molding machine comprises a plasticating unit (B') for plasticating a thermoplastic resin, an injecting unit (A) connected to the plasticating unit (B') through a connecting passage (12) to inject the plasticated resin into a mold, and a buffering unit having a buffering chamber (21) and receiving the resin plasticated in the plasticating unit (B'). The buffering unit is contained in the plasticating unit (B') and is located in a longitudinal direction of the plasticating unit (B'). <IMAGE>
Patent EP-1389510-B1 (EP)
Inventor: SCHNYDER EUGEN
IPC: B30B5/04
Filed: 2003-06-23
Granted: 2010-05-05
Abstract: The machine (10) to produce a fiber web (38), e.g. for the production of fiberboards, has a recirculating press belt (12) forming a press gap with a counter surface (14) at a drum (16). A number of successive press units (20) are deployed in the direction (L) of web travel, to press the belt with the web against the counter surface. The press units have at least a partially independent control (30) to set the pressure applied to the web to set and adjust its bulk density profile, and at least one press unit is an adjustable bending roller. The press gap can be heated at least on one side.
Patent EP-1449497-B1 (EP)
Inventor: DALY ANDREW SEAN GORDON
IPC: A61D9/00
Filed: 2003-10-24
Granted: 2007-06-06
Abstract: A tendon and ligament support for a limb joint, such as a ankle joint, and in particular to an animal joint such as a horse's fetlock joint, is provided. Tendon and ligament strain during exercise or rest may be limited by limiting the degree of joint movement to a safe level. The level of support (118) may be adjusted. A first collar (1,112) is adapted to embrace the limb above the joint and a second collar (3,113) is adapted to embrace the limb below the joint. A connecting means (4) provides articulation between and separation of the two collars, and is adapted to provide limited elongation of the ligaments and /or tendons under load, and includes means arranged so as to exert a resistance (21,61,71,114,115) to joint movement over a predetermined range of joint rotation. The connecting means may be a hinge (11) or a stiff bendable connecting piece. The resistance-exerting means may be a connector of high tensile strength and limited elasticity (61,71,115) connected to one or more points on each of the collars, preferably adapted so as to mimic an artificial tendon or ligament arrangement. <IMAGE>
Patent EP-1342516-B1 (EP)
Inventor: ZUBCEVIC ESAD
IPC: B21D51/26
Filed: 2000-12-22
Granted: 2004-08-11
Abstract: A method for fastening a bottom part (40) to a can body (31). The method comprises positioning the bottom part at one end of the can body such that a rim portion of the bottom part is in abutting engagement with a radial flange formed at said one end, rotating the can body in relation to at least one bending or folding tool (43-45), and moving said bending or folding tool radially in relation to the can body along a predetermined path corresponding to the cross sectional shape of the can body, so as to fasten the bottom part to the can body. <??>Furthermore the invention relates to an apparatus (13) for fastening a can bottom to a can body having a non-circular cross-sectional shape. The apparatus comprises means for rotating a can body with a can bottom positioned at one end thereof such that a rim portion of the bottom is in abutting engagement with a radial flange formed at said one end of the can body, at least one bending or folding tool (43-45) movable radially in relation to the can body positioned on said rotating means, and means (46) for moving or biasing the bending or folding tool radially into engagement with said rim portion and/or with said radial flange (41,42), so as to bend or fold said rim portion and/or said flange. <??>Additionally the invention relates to a can making facility comprising the aforementioned apparatus.A method for fastening a bottom part (40) to a can body (31). The method comprises positioning the bottom part at one end of the can body such that a rim portion of the bottom part is in abutting engagement with a radial flange formed at said one end, rotating the can body in relation to at least one bending or folding tool (43-45), and moving said bending or folding tool radially in relation to the can body along a predetermined path corresponding to the cross sectional shape of the can body, so as to fasten the bottom part to the can body. <??>Furthermore the invention relates to an apparatus (13) for fastening a can bottom to a can body having a non-circular cross-sectional shape. The apparatus comprises means for rotating a can body with a can bottom positioned at one end thereof such that a rim portion of the bottom is in abutting engagement with a radial flange formed at said one end of the can body, at least one bending or folding tool (43-45) movable radially in relation to the can body positioned on said rotating means, and means (46) for moving or biasing the bending or folding tool radially into engagement with said rim portion and/or with said radial flange (41,42), so as to bend or fold said rim portion and/or said flange. <??>Additionally the invention relates to a can making facility comprising the aforementioned apparatus. <IMAGE> <IMAGE>
Patent EP-1384699-B1 (EP)
Inventor: SANFILIPPO DOMENICO
IPC: B01J19/00
Filed: 2003-07-15
Granted: 2005-04-13
Abstract: Process for the production of synthesis gas from heavy charges by partial oxidation and subsequent cooling of the synthesis gas by direct injection of water followed by separation of the water effected by means of an adduction pipe surrounded by a concentric tube open at both ends so as to form a ring through which the cooled gas and the water can rise.
Patent EP-1482785-B1 (EP)
Inventor: LEANDER LEIF
IPC: A01K61/95
Filed: 2003-02-21
Granted: 2005-06-22
Abstract: The present invention relates to a method for automatic injection of compounds into living fish. The fish is fed on a transporter (1) placed in compartments (8) with each fish oriented transversely to the feeding direction. Each fish is measured with respect to size, and an injection unit (20) is adjusted for each measured fish for positioning against an injection point at the fish depending on the size of the measured fish. The injection takes place by means of an insertion movement to a chosen insertion depth by means of a cannula at the chosen insertion point on each fed fish and administering of the compound via the cannula.
Patent EP-1489968-B1 (EP)
Inventor: CARNEY WALTER P
IPC: G01N33/86
Filed: 2003-02-27
Granted: 2009-02-18
Abstract: The present invention describes methods of examining, screening over time, and monitoring the outcome of a cancer patient who is undergoing treatment or therapy. More specifically, the invention provides a method of monitoring the progression of disease, or the effectiveness of cancer treatment, in a cancer patient by measuring the levels of one or more analytes of the plasminogen activator (uPA) system, namely, uPA, PAI-1 and the complex of uPA:PAI-1, in a sample taken from the cancer patient, preferably, before treatment, at the start of treatment, and at various time intervals during treatment. An increase or elevation in the levels of one or more of the PA system analytes in the cancer patient compared with the levels one or more of the respective PA system analytes in normal control individuals serves as an indicator of cancer advancement or progression.
Patent EP-1483483-B1 (EP)
Inventor: FRUTSCHI HANS ULRICH
IPC: F01K21/04
Filed: 2003-03-11
Granted: 2006-10-18
Abstract: In a power generation unit, especially in a gasturbo group, a gaseous process fluid is guided in a closed cycle. The gaseous process fluid flows through a compression device ( 1 ), a heater ( 6 ) and an expansion device ( 2 ), especially a turbine. Downstream from the expansion device at least one heat sink ( 11, 13 ) is arranged in which the gaseous process fluid is cooled before it is returned to the compressor device ( 1 ). At least one heat sink includes a waste heat steam generator in which an overheated amount of steam ( 26 ) is generated that is added to the compressed gaseous process fluid. Together with the gaseous process fluid the steam flows through the heater ( 6 ) if necessary and is expanded together with it. The expanded steam condenses in the waste heat steam generator ( 11 ) and another heat sink ( 13 ); the condensate is processed in a filter ( 16 ) and is returned to the waste heat steam generator ( 11 ) under pressure via a feed pump ( 18 ). Due to the closed process any kind of process fluid and process filling for controlling performance can be used.
Patent EP-1487777-B1 (EP)
Inventor: BOTELLA ASCUNCION PABLO
IPC: C07C211/50
Filed: 2003-03-25
Granted: 2008-01-02
Abstract: A method of preparing diaminodiphenylmethane and higher homologues thereof from aniline and formaldehyde in the presence of heterogeneous solid acid catalysts selected from (a) delaminated zeolites and/or (b) metal silicate catalysts having an ordered mesoporous pore structure.