baber/WOPTO huggingface dataset:
Patent PT-1913947-E (PT)
Title: Combination therapy for the treatment of cancer
Inventor: PATEL BHARVIN KUMAR
IPC: A61K31/337
Filed: 2005-04-15
Abstract: The present invention relates to a method of treating cancer in a patient comprising administering an effective amount of a Survivin antisense oligonucleotide in combination with an effective amount of an additional anti-cancer agent.
Patent PT-2238392-E (PT)
Title: Fastening system for a plate-shaped structural element
Inventor: NEUNER ROLAND
IPC: F24J2/04
Filed: 2009-01-30
Abstract: A fastening system for a plate-shaped structural element on a pitched roof is provided. The plate-shaped structural element is bordered in a water-tight manner in a frame and fully replaces the roof covering, and the eaves-side and ridge-side cross beams of the frame which run transversely to the ridge-eaves direction have profiles which are matched to each other and engage in each other. The top side of the eaves-side cross beam has a mounting that surrounds the edge of the plate-shaped structural element, and the bottom side thereof has a support for fastening to the roof structure. The support includes a web that extends from the mounting to the support, a protrusion extending beneath the mounting and receives an extension that extends from the ridge-side cross beam thereof.
Patent PT-2663561-E (PT)
Title: Novel heterocyclic derivatives and their use in the treatment of neurological disorders
Inventor: KONSTANZE HURTH
IPC: C07D487/04
Filed: 2012-01-11
Abstract: The invention relates to novel heterocyclic compounds of the formula 
                         
in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, combinations thereof, and their use as medicaments, particularly for the treatment of Alzheimer's Disease or diabetes via inhibition of BACE-1 or BACE-2.
Patent PT-512693-E (PT)
Inventor: SUTTON ANDREW DEREK
IPC: B01J13/02
Filed: 1992-04-10
Abstract: Microcapsules are prepared by a process comprising the steps of (i) spray-drying a solution or dispersion of a wall-forming material in order to obtain intermediate microcapsules and (ii) reducing the water-solubility of at least the outside of the intermediate microcapsules.Suitable wall-forming materials include proteins such as albumin and gelatin.The microcapsules have walls of 40-500 nm thick and are useful in ultrasonic imaging. The control of median size, size distribution and degree of insolubilisation and crosslinking of the wall-forming material allows novel microsphere preparations to be produced.
Patent PT-655442-E (PT)
Inventor: MATSUO MASAAKI
IPC: C07D401/12
Filed: 1994-11-25
Abstract: A compound of the following general formula : <CHEM>  wherein   X   is carbonyl or sulfonyl; Y   is bond or lower alkylene; R<1>   is halogen, lower alkyl, halo(lower)alkyl, aryloxy, nitro or amino which may have 1 or 2 and same or different substituent(s) selected from lower alkyl, acyl and lower alkanesulfonyl; R<2>   is aryl or an aromatic hetero(mono- or bi-)cyclic group, and each of which may have 1, 2 or 3 suitable substituent(s); R<3>   is hydrogen or lower alkyl; R<4>   is   (i) a group of the formula -SO2-R<5> in which R<5> is lower alkyl or aryl optionally substituted with lower alkyl or lower alkoxy,   (ii) a group of the formula <CHEM> in which R<6> is aryl optionally substituted with lower alkyl or lower alkoxy, or   (iii) a group of the formula -A-(Z)p in which   A   is bond, lower alkylene, lower alkenylene or lower alkynylene, Z   is hydrogen, halogen, hydroxy, nitrile, amino, cyclo(lower)alkyl, aryl, aryloxy, acyl, acylamino, lower alkanesulfonylamino, arylsulfonylamino or an aromatic hetero(mono- or bi-)cyclic group, and each of the cyclic group may have 1, 2 or 3 suitable substituent(s), and p   is 1, 2 or 3; and     n   is 0, 1 or 2; provided that when n or p is more than 1, these R<1> and Z may be the same or different group respectively; or its pharmaceutically acceptable salt, processes for their preparation and pharmaceutical compositions comprising them.
Patent PT-655530-E (PT)
Inventor: BOEVE JAN ANTONIE
IPC: E01C5/08
Filed: 1994-11-16
Abstract: The invention relates to a groundcovering element, consisting of a plurality of components (1) with links (2,3) in between, a method for the manufacture thereof and a method for the manufacture of a mould (24, 25, 26, 27, 29, 30). According to the invention it is provided that the links between the components are deformable and possibly flexible, resulting in a groundcovering element that is easy to lay, offers better possibilities of adjustment to various desired surfaces to be covered and is considerably more suitable for a more or less undulating terrain. In the method of manufacture, one steel mould part (34) cooperates with many rubber ones (31), so that with little investment a high production rate is obtained. <IMAGE>
Patent PT-668763-E (PT)
Inventor: GRIEG NIGEL H
IPC: A61P25/28
Filed: 1993-11-23
Abstract: An improved method of cholinomimetic therapy for cognitive impairments associated with aging and Alzheimer's disease comprising treating a patient with an effective amount of phenserine or a pharmaceutically acceptable salt and derivatives.
Patent PT-707580-E (PT)
Inventor: KALLSTROM LARS AKE
IPC: A61K31/443
Filed: 1994-07-08
Abstract: A novel compound form of magnesium omeprazole, i.e. with a degree of crystallinity which is higher than 70% as determined by x-ray powder diffraction, useful in the manufacture of pharmaceutical formulations, the use of the product and the process for its production are described.
Patent PT-778597-E (PT)
Inventor: HOFSASS MARCEL
IPC: H01H71/16
Filed: 1996-09-19
Abstract: The switch has a movable contact part (18). This cooperates at least with a first counter contact (19) forming, with this, a first switch contact (20). This contact is opened or closed in dependence in the temperature of the switch mechanism (16). The switch has at least a first heat resistor (35). This resistor is provided on the movable contact part (18). The switch may also have a second heat resistor which may also be formed on the movable contact part (18). This cooperates with a second counter contact forming a second switch contact. The second switch contact has a switch state opposite that of the first contact. The switch mechanism may be formed as an alternating switch. In a first switch state, in which the first switch contact is closed, the first heat resistor is connected in series between switch terminals. In a second switch state, in which the second switch contact is closed, the second resistor is connected in series between a different pair of terminals.
Patent PT-833643-E (PT)
Inventor: BRENNER GERALD S
IPC: A61P43/00
Filed: 1996-06-03
Abstract: PCT No. PCT/US96/08284 Sec. 371 Date Dec. 3, 1997 Sec. 102(e) Date Dec. 3, 1997 PCT Filed Jun. 3, 1996 PCT Pub. No. WO96/39149 PCT Pub. Date Dec. 12, 1996Disclosed is a method for treating and preventing bone loss in patients by administering a formulation of anhydrous alendronate sodium. Also described is a pharmaceutical dosage form of said anhydrous alendronate sodium, being anhydrous 4-amino-1-hydroxy-butylidene-1,1-bisphosphonic acid, monosodium salt, in a pharmaceutically acceptable excipient.
Patent PT-961555-E (PT)
Inventor: SAND JEFF WALDO
IPC: A43B7/20
Filed: 1998-01-15
Abstract: PCT No. PCT/US98/00336 Sec. 371 Date Jul. 2, 1999 Sec. 102(e) Date Jul. 2, 1999 PCT Filed Jan. 15, 1998 PCT Pub. No. WO98/31247 PCT Pub. Date Jul. 23, 1998An ankle support assembly for use in combination with a soft-style snowboard boot. The assembly includes a rigid heel cup and a high back support for supporting the calf region of the snowboard rider. The high back support includes an extension member having a bottom end portion that is coupled within a pocket formed in the upper rear region of the heel cup. The coupling permits the high back support to float about a pivot axis that is translatable a predetermined amount along transverse, longitudinal and vertical axes of the ankle support assembly so as to enable articulation of said ankle support device in a manner that closely approximates the articulation of the foot and ankle of the snowboard rider. A tether is provided to prevent inadvertent decoupling of the high back support from the heel cup. Also included is a length adjustable tension cable to provide forward lean adjustment for the assembly.
Patent PT-998315-E (PT)
Inventor: MATTERN MARKUS
IPC: F41B6/00
Filed: 1998-07-18
Abstract: Featured is a method for injection of a payload into the tissues of an organism or a body, including the steps of generating forces by electromagnetic repulsion and accelerating the payload to be injected, using the generated electromagnetic forces. The payload is thereby accelerated to a velocity sufficient for the payload to pass through the skin of the organism and be disposed in the subcutaneous tissues. The method further includes providing an electromagnetic force generating device that generates forces electromagnetically in a predetermined direction responsive to an electric current flowing through the device, wherein the step of generating includes passing an electric current through the electromagnetic force generating device to generate the electromagnetic repulsive forces used for accelerating the payload. Also featured is a electromagnetic force generating mechanism that includes a conductive member, which is configured so as to generate electromagnetic repulsive forces in a given direction to accelerate the payload responsive to a pulsed current passing through the conductive member. Additionally featured is an electromagnetic transdermal injection device including such an electromagnetic force generating mechanism, an electrical power supply and a switch that selectively interconnects the power supply and force generating mechanism to accelerate a payload such as a medicine.
Patent PT-1032282-E (PT)
Inventor: MENTZEL EDGAR
IPC: A24D3/00
Filed: 1998-11-10
Abstract: A filter for tobacco products, in particular cigarettes, is made of a cellulose nonwoven fabric produced by an air-laid process and spirally rolled.
Patent PT-1105986-E (PT)
Inventor: BANNASCH RUDOLF
IPC: H04B11/00
Filed: 1999-08-23
Abstract: A process and system for the transfer of information, which is suitable in particular for digital information transfer. At least one information signal is created, consisting of at least one reference component and at least one information component, wherein at least one of these components has a temporally continuous frequency change during the transfer and, in addition, the reference component and the information component form discrete states for the provision of bit patterns. After receiving, the at least one component with frequency change is transferred into constant intermediate frequencies. From the spectrum of the constant intermediate frequencies, in each case the best-suited signal components are selected, separated as constant frequencies from interference portions and evaluated with regard to the relevant information parameters. This allows a signal transfer with high quality and high transfer rate, even over great distances, for example, under water. Furthermore, a suitable evaluation system is described.
Patent SG-789-G (SG)
Title: Novel n-nitroso compounds,compositions containing such compounds and processes for their preparation
IPC: A61K31/445
Filed: 1989-01-05
Abstract: The invention concerns N-nitroso compounds having the general formula:   <IMAGE> (I)  wherein A is lower alkyl or halolower alkyl; B is hydrogen; lower alkenyl; lower alkynyl; 3-6 C cycloalkyl; -RSO2NR3R4, or lower alkyl optionally monosubstituted with lower alkoxy, or 3-6 C cycloalkyl; R is straight or branched 2-5 C alkylene, optionally monosubstituted with SO2NR3R4 or CONR3R4, said alkylene always containing at least two carbon atoms separating the nitrogen atom of the urea from any SO2NR1R2 or SO2NR3R4; R1 and R2 are the same or different and selected from hydrogen, 5-6 C cycloalkyl, lower alkoxy, phenyl, benzyl, and straight or branched 1-6 C alkyl, optionally monosubstituted with hydroxy, lower alkoxy, SO2NR3R4, or CONR3R4; R1 and R2 may also together form a 4-5 C alkylene; and R3 and R4 are the same or different and selected from hydrogen or lower alkyl, or R3 and R4 together are a 4-5 C alkylene, together with pharmaceutical compositions thereof; processes for their manufacture, and methods of treatment. The compounds of formula (I) have antitumor activity.
Patent SG-2495-G (SG)
Title: Takeout jaws
Inventor: DENNEY MICHAEL L
IPC: C03B9/44
Filed: 1995-01-09
Abstract: A takeout jaw for use in a bottle-forming machine is formed in a semicircular shape and contains a spring clip for holding immovably a piece of non-metallic contact material within a pocket in the body of the takeout jaw.
Patent SG-80386-G (SG)
Title: Copper convered hard paper made of a compressed fire-inhibiting laminate
IPC: B32B15/00
Filed: 1986-10-02
Abstract: Increased elasticity of a laminate is obtained by adding 5-20% by weight of a blocked polyetherurethane component from a reaction product of polyethylene glycol, polypropylene glycol and p-nonylphenol with toluene-2,4-diisocyanate having the following composition: -polyethylene glycol 15-20% by weight -polypropylene glycol 50-60% by weight -toluene-2,4-diisocyanate  8-12% by weight -nonylphenol 10-15% by weight -  in the manufacture of a fire resistant laminate based on a cellulose-containing substrate material and an impregnating varnish made up of a phenol-resol with additives of plasticizers and flame retardants. A copper-laminated hard paper made of this phenolic resin laminate is distinguished by reduced punching resistance and stripping resistance.
Patent SG-85790-G (SG)
Title: Analogue-to-digital converter circuit
IPC: H03M1/00
Filed: 1990-10-24
Abstract: By means of a controlled integrator, a noise component in the residual signal which is left after a conversion cycle of an analogue-to-digital converter can be eliminated for the major part. It is then possible to digitize this residual signal and thus to obtain additional bit information, as a result of which the range and the resolving power of the analogue-to-digital converter are increased.
Patent IE-780105-L (IE)
Title: Acrylonitrile-vinyl chloride copolymer
IPC: C08F220/00
Filed: 1978-01-18
Abstract: The invention relates to a process for the production of a chemically uniform acrylonitrile vinyl chloride copolymer in an aqueous emulsion in the presence of a redox catalyst and with a fluctuating concentration of at least one iron salt in the reaction medium wherein the polymerization reaction is carried out at a pH value of from 2 to 6 in the presence of a mixture of an iron salt and a complex former, the complex former having certain apparent stability constants of the iron-II-complex and of the iron-III-complex.
[US4334046A]
Patent IE-36044-L (IE)
Title: Process for dyeing material
IPC: D06P1/00
Filed: 1972-01-28
Abstract: 1386073 Treating dyed textiles J & P COATS Ltd 4 Feb 1972 [29 Jan 1971] 3537/71 Heading D1B Textile materials are dyed in aqueous or non-aqueous media followed by drying the material which is then treated in a cleaning media consisting of acetone in a proportion from 100% to 50% and a liquid neutral diluent in a proportion of 0% to 50%. Water may be employed as diluent, the preferred temperature for cleaning being 40 to 50C, the material preferably being dried after treatment with the cleaning media by subjection to a sub-atmospheric pressure below the vapour pressure of the cleaning substance.
[GB1386073A]
Patent IE-880288-L (IE)
Title: Dental composition
IPC: A61K6/02
Filed: 1988-02-03
Abstract: The compsn., for treatment of caries, acute, sub-acute or chronic inflammatory lesions of the pulp, the tooth root or the bony substance surrounding them, consists of a mixt. of 0.1-30wt.% Ipriflavone, 0.5-15% Triamcinolone, opt. 0.1-10% Dioxicicline or their salts, and opt. 1-20% Lidocaine, with 35-99.4% of one or more known auxiliary agent.
Patent IE-38976-L (IE)
Title: Curable polyester molding compositions
IPC: C08L67/00
Filed: 1974-03-07
Abstract: A process for the manufacture of curable unsaturated polyester molding compositions. To a mixture of A. AT LEAST ONE UNSATURATED POLYESTER, B. AT LEAST ONE COPOLYMERIZABLE OLEFINICALLY UNSATURATED COMPOUND, C. AN ALKALINE EARTH METAL OXIDE AND/OR HYDROXIDE, D. AT LEAST ONE INHIBITOR AND, OPTIONALLY, E. CONVENTIONAL FILLERS, REINFORCING AGENTS, INERT SOLVENTS, POLYMERIZATION ACCELERATORS AND/OR OTHER AUXILIARIES CONVENTIONALLY USED IN THE PROCESSING OF POLYESTER MOLDING COMPOSITIONS, THERE IS ADDED FROM 0.005 TO 1% BY WEIGHT, BASED ON UNSATURATED POLYESTER RESIN (A) PLUS (B), OR AT LEAST ONE COMPOUND OF THE GENERAL FORMULA Z On Xm WHERE Z denotes hydrogen, deuterium, phosphorus, boron, aluminum, gallium, silicon, germanium, tin, lead, antimony, bismuth, zinc, titanium, zirconium or sulfur and X denotes fluorine, chlorine, bromine, iodine or a mixture thereof and n denotes 0, 1 or 2 and m denotes 2, 3, 4, 5 or 6. The process of the invention is used for rapid thickening of molding compositions of unsaturated polyester resins.
[US3894984A]
Patent IE-36332-L (IE)
Title: Polyamide fibres
IPC: D01F6/60
Filed: 1972-04-27
Abstract: 1393011 Polyamide fibres E I DU PONT DE NEMOURS & CO 27 April 1972 [28 April 1972 (2) 17 Aug 1971 (2)] 19574/72 Heading B5B [Also in Division C3] Fibres and films are made from a polyamide having an inherent viscosity of at least 2À5 and consisting essentially of recurring units I and II, or III, or I and II and III wherein I is II is and III is When I and II are present in the polymer they are present in substantially equimolar amounts. R, R<SP>1</SP> and R<SP>11</SP> groups, which may be the same or different, are such that at least 95 mol per cent of the total R, R<SP>1</SP> and R<SP>11</SP> consist of single rigid radicals with extended bonds (as herein defined), or a series of such rigid radicals linked by extended bonds, rigid ring radicals may also be linked by azo or azoxy groups. n is 0 or 1. The fibres and films have a filament or film tenacity of 18 to 14 g.p.d., a filament or film breaking elongation of 3À5 to 8À0% and crystalline regions with a primary appararent crystallite size of 0 to 52. R, R<SP>1</SP> and R<SP>11</SP> groups mentioned are 1,4- phenylene; 4,4<SP>1</SP>-biphenylene; 1,5-naphthylene; 2,6-naphthylene; trans- 1 ,4-cyclohexylene; 2,5- pyridylene; trans-trans-4,4<SP>1</SP>-bicyclohexylene and 1,4-phenylene groups linked by transvinylene, ethynylene, azo or azoxy ; R may also be selected from trans-vinylene, ethynylene, trans-, trans-1,4-butadienylene or 2,4<SP>1</SP>-trans-vinylenephenylene and R<SP>11</SP> may be 2,4<SP>1</SP>-transvinylene-phenylene. All may be substituted or unsubstituted. Fibres are prepared by wet-spinning; a dope of the polymer being extruded through a layer of an inert non-coagulating fluid into a coagulating bath. The solvent may consist of either sulphuric acid of at least 98% concentration, chlorosulphuric acid or fluorosulphuric acid and the polymer concentration is at least 30 grams per 100 ml. of solvent.
[GB1393011A]
Patent IE-870700-L (IE)
Title: Thiazepine compounds
IPC: C07C323/62
Filed: 1987-03-16
Abstract: The compound of formula:- <CHEM> and the pharmaceutically acceptable salts thereof possess neuroleptic activity with a much reduced incidence of side effects such as acute dystonia, acute dyskinesia and tardive dyskinesia.
[EP0240228A1]
Patent IE-35345-L (IE)
Title: Electrically heated vessel
IPC: A47J27/21
Filed: 1971-06-10
Abstract: 1362775 Kettles N C JOSEPH Ltd 10 June 1971 [17 June 19701 29318/70 Heading A4 [Also in Divisions H1 and H5] Steam generated near the open end 19 of hood 18 passes upwardly to a vapour space 23 above the maximum water level 21 and passes through a pipe 17 to impinge on the thermal element 16 of a thermal switch mounted externally of vessel 10 which cuts the power supply to immersion heater 14. A smaller immersion heater may be simultaneously switched on to maintain the water temperature. A reset button 28 is provided to reconnect immersion heater 14. The thermal switch is mounted in the socket 15 of the immersion heater. A second thermal switch with its thermal element adjacent a wall of vessel 10 is provided for cutting the supply should the immersion heater become exposed e.g. when the vessel boils dry.
[GB1362775A]
Patent IE-780742-L (IE)
Title: Isoxazolylmethyl-benzomorphanes
IPC: C07D261/08
Filed: 1978-04-14
Abstract: Compounds of the formula <IMAGE> wherein R1 is methyl, ethyl or propyl; and R2 is hydrogen, methyl or ethyl; and non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as analgesics and morphine antagonists.
[US4133888A]
Patent IE-42567-L (IE)
Title: Apparatus for checking of the pairing of wires
IPC: G01R31/04
Filed: 1976-04-15
Abstract: 1502043 Testing insulated conductors COMPAGNIE INDUSTRIELLE DES TELECOMMUNICATIONS CIT-ALCATEL SA 31 March 1976 [16 April 1975] 12931/76 Heading G1U In detecting incorrect pairing of twisted pairs in a multi-wire telecommunications cable, a signal is injected into successive ones of the first wires of the pairs, and signals from the second wires of the pairs due to induction are detected. The cable has pairs ai, a<SP>x</SP>i;...an, a<SP>x</SP>n at one end and pairs bl, b<SP>x</SP>l;... bn, b<SP>x</SP>n at the other. These are connected to male multi-way connectors, which fit female connectors on the apparatus front-panel, Fig.2 (not shown). This connects ai ... an ie the first wires of the n pairs to the outputs of a demulti-plexer DM, and the corresponding second wires at the other cable end b<SP>x</SP>1... h<SP>x</SP>n to detector D1... Dn. A 10Hz oscillator 01 feeds a counter CT whose outputs provide the address inputs to the demultiplexer DM, which thus sequentially directs 2MHz signals from oscillator 02 to successive first wires ai ... an. The counter CT outputs are also de-coded D.C. to illuminate one of lamps L1-Ln on the front panel via outputs Sl-Sn, corresponding to the energized wire. Whichever second wire is twisted with the energized first wire provides an induced voltage to one of the detectors D1-Dn. That detector provides an output S<SP>x</SP>1 ... S<SP>x</SP>n to illuminate a second lamp on the front panel. These lamps are arranged, such that correctly paired wires illuminate lamps side-by-side, Figs.2, 3B, 4B, 5B, 5C (not shown). A comparator CP compares the de-coder D.C. output and the detector outputs and if these do not correspond to correctly paired wires, a low output to NOR-gate PN causes that gate to block oscillator 01, thus stopping further stepping, and the front-panel lamps stay illuminated to indicate a fault. The stepping is recommenced by operation of a push-button BD which actuates a monostable BM to give a high output, thus removing the blocking signal Ebto the oscillator.
[GB1502043A]
Patent IE-840929-L (IE)
Title: Guide for femoral neck osteotomy.
IPC: A61B17/56
Filed: 1984-04-13
Abstract: A guide for femoral neck osteotomy comprises a longitudinal rod having attaching structure at the lower end thereof for securing the rod to a femur at the greater trochanter. A transversely extending support arm is secured to the rod adjacent the lower end thereof, and a guide bar is connected to the support arm. The guide bar has at least one elongate planar surface disposed at an angle of 45 DEG to the axis of the rod. In use, the rod is aligned with the long shaft axis of the femur and attached to the femur at the greater trochanter. The rod is manipulated until the support arm and the long shaft axis of the tibia are disposed in the same plane. This procedure properly positions the elongate planar surface of the guide bar whereby an instrument in engagement with that surface traverses the femoral neck at an angle of 45 DEG to the long shaft axis of the femur.
[US4621630A]