baber/WOPTO huggingface dataset:
Patent WO-2021050634-A1 (WO)
Title: Recombinant microorganisms for in vivo production of sulfated glycosaminoglycans
Inventor: BADRI ABINAYA
IPC: C12P11/00
Filed: 2020-09-10
Abstract: In order to produce chondroitin sulfate in an animal-free manner, engineered E. coli host cells were modified so as to reduce expression of an endogenous gene for fructosyltransferase (kfoE); reduce expression of an endogenous gene for 3'- phosphoadenosine-5'-phosphosulfate reductase (cysH); and express one or more exogenous sulfotransferases. Expression of proteins forming ATP -binding cassette transporters were also reduced to limit export of glycosaminoglycans from the cells. The recombinant microorganisms are able produce all three components identified for chondroitin sulfate production - chondroitin, sulfate donor, and sulfotransferase. These modified E. coli are capable of complete, essentially one-step biosynthesis of chondroitin sulfate at a variety of sulfation levels from simple microbial media components and glucose. This is a major advantage over current production methods that depend on the natural distribution of chondroitin sulfate types in the animal tissue.
Patent WO-2022060370-A1 (WO)
Title: Responsive actions based on spatial input data
Inventor: DE BREBISSON CYRILLE
IPC: G09G5/08
Filed: 2020-09-21
Abstract: Examples are described herein for leveraging out-of-bounds spatial input data to trigger various responsive actions. In various examples, a graphical element controlled by a pointing device may be detected at an edge of a display. Based on the detecting, the pointing device may be caused to provide out-of-bounds spatial input data. Based on the out-of-bounds spatial input data, user intent to trigger performance of a responsive action may be determined, and may trigger performance of the responsive action.
Patent WO-2022066180-A1 (WO)
Title: Copolymerized superabsorbent polymers
Inventor: YANG KAIYUAN
IPC: C08F22/06
Filed: 2020-09-28
Abstract: Described herein are novel super absorbent materials. The super absorbent materials are copolymerized with strong or super strong ionizable monomers and bulky counter ions or select metal salts. The copolymer-based super absorbent materials have significantly improved absorbance properties. The compositions and methods described herein are useful in a variety of absorbent products.
Patent WO-2021062359-A1 (WO)
Title: Methods for treating acute wounds and improving outcomes
Inventor: SMIELL JANICE
IPC: A61L27/60
Filed: 2020-09-28
Abstract: The present disclosure provides methods for treating acute wounds and improving outcomes by applying to an acute wound a skin substitute that is an organotypic human skin equivalent comprising NIKS cells. In certain embodiments, the closed wound has improved vascularity, improved pigmentation, decreased thickness, decreased pain, increased pliability, increased surface area, decreased stiffness, decreased itching, improved color, or any combination thereof, as assessed by an observer or by the subject, as compared to an autograft or another skin substitute.
Patent WO-2021067792-A1 (WO)
Title: A method for differentiating innate lymphoid cells for immunotherapy
Inventor: HOROWITZ NINA BERYL
IPC: A61K39/00
Filed: 2020-10-02
Abstract: Natural killer cells are differentiated to an intraepithelial innate lymphoid cells (ielLC1)-like cell, with an increase in cytotoxic activity. Specifically, the disclosure provides a method for differentiating mammalian natural killer cells to adapt an ielLC1-like phenotype, the method comprising: differentiating peripheral natural killer (NK) cells in the presence of IL-15 and epithelial cells or plate coatings that mimic features of epithelial cells, to generate CD49a+ CD103+ cells having features and phenotype of ielLC1s, with enhanced cytotoxic activity and expression of Th1 type cytokines.
Patent WO-2021080918-A1 (WO)
Title: Sensor shield
Inventor: GENTILE MATTHEW
IPC: G01N27/38
Filed: 2020-10-19
Abstract: A sealing assembly for forming a liquid-tight seal around a component is provided. The sealing assembly includes an end cover, a sleeve, a gasket, and a sealing clamp. Provided is also a holder that cooperates with an end cover of the sealing assembly to maintain the component and sealing assembly in a generally horizontal position for a period of time.
Patent WO-2021081348-A1 (WO)
Title: Methods for treating patients having cfi mutations with recombinant cfi proteins
Inventor: MCLAUGHLIN JAMES
IPC: A61P27/02
Filed: 2020-10-23
Abstract: The present disclosure provides methods for treating, preventing, or inhibiting diseases in patients having one or more CFI mutations.
Patent WO-2021113140-A1 (WO)
Inventor: LANGRAND SYLVAIN
IPC: G06F9/451
Filed: 2020-11-25
Abstract: Techniques for providing information and functionalities based on a video game lifecycle and user context are described. In an example, a computer system presents a page as a single user interface to information and functionalities associated with a video game. The page is generated based on a layout that is specific to a phase of the lifecycle of the video game. The page is also customized based on a context of the user of the video game. The page is accessible to the user across the different phases of the video game's lifecycle. The computer system updates the phase through the different phases and based on changes to the user context, such that the page presents the most relevant and needed information and functionalities at any point in time.
Patent WO-2021126521-A1 (WO)
Title: Real-time intradialytic hypotension prediction
Inventor: KOTANKO PETER
IPC: A61B5/0205
Filed: 2020-12-02
Abstract: Techniques for real-time intradialytic hypotension (IDH) prediction are disclosed. A system obtains historical hemodialysis treatment data that is segmented into sets of machine learning training data based on temporal proximities to IDH events and trains a machine learning model to predict IDH events based on the sets of machine learning training data.
Patent WO-2021126615-A1 (WO)
Inventor: AXELROD BLAKE
IPC: A61B5/022
Filed: 2020-12-09
Abstract: L'invention concerne un dispositif de mesure de la tension artérielle pour mesurer la tension artérielle d'un patient à partir du bras d'un patient. Le dispositif de mesure de la tension artérielle peut comprendre un brassard brachial externe pouvant être monté autour du bras du patient pour déterminer des mesures de la tension artérielle absolue discrètes à partir de l'artère brachiale du patient, et un capteur pouvant être monté à proximité du brassard brachial externe pour mesurer une forme d'onde de pulsatilité continue à partir de l'artère brachiale du patient. Les mesures de la tension artérielle absolue discrètes sont combinées à la forme d'onde de pulsatilité continue mesurée pour un suivi de la tension artérielle (BP) battement à battement par une analyse d'onde pulsée (PWA) au niveau de l'emplacement brachial pour fournir une surveillance continue et non-invasive de la tension artérielle de battement à battement.
Patent WO-2021141751-A1 (WO)
Title: Arginase inhibitors and methods of use
Inventor: ACHAB ABDELGHANI ABE
IPC: C07F5/02
Filed: 2020-12-18
Abstract: Described herein are compounds of Formula I or a pharmaceutically acceptable salt thereof. The compounds of Formula I act as arginase inhibitors and can be useful in preventing, treating or acting as a remedial agent for arginase-related diseases.
Patent WO-2021178213-A1 (WO)
Inventor: POSPISIL FRANK
IPC: E04B5/10
Filed: 2021-02-25
Abstract: A composite structure for a building that includes at least one structural panel and at least one metal corrugated panel, where the at least one structural panel is secured to said at least one metal corrugated panel.
Patent WO-2021195440-A1 (WO)
Inventor: SISCO SCOTT W
IPC: C08F216/20
Filed: 2021-03-25
Abstract: A crosslinking material, the crosslinking material comprising the reaction product of a reaction mixture comprising: (i) a cyclic unsaturated acid anhydride and/or diacid derivative thereof; (ii) an ethylenically unsaturated monomer; and (iii) an alcohol, amine and/or thiol, wherein the cyclic unsaturated acid anhydride and/or diacid derivative thereof is partially- esterified by reaction with the alcohol, amine and/or thiol; and wherein the crosslinking material has an acid number of at least 100 mg KOH/g.
Patent WO-2021211360-A1 (WO)
Inventor: BERGMAN ERIC
IPC: A61M1/16
Filed: 2021-04-09
Abstract: This disclosure relates to a blood treatment system including a blood treatment machine, a dialyzer configured to be coupled to the blood treatment machine, a blood line having a first end configured to be connected to the dialyzer and a second end configured to be connected to a needle for insertion into a patient, and one or more sensors operable to transmit, to the blood treatment machine, data related to tension along the blood line. The blood treatment machine is configured to take action in response to the data received from the one or more sensors.
Patent WO-2021225751-A1 (WO)
Title: Mobile hybrid electric power system
Inventor: KUZNETSOV STEPHEN B
IPC: H02J11/00
Filed: 2021-04-09
Abstract: A system (100, 200, 500, 600, 700) includes a prime mover (105, 205, 505, 605, 705) configured to rotate a shaft (107). The system also includes a wound rotor induction generator (WRIG) (110, 210, 510, 610, 710). The WRIG includes a rotor (111, 211) coupled to the shaft of the prime mover and configured to rotate when the shaft rotates, where the rotor includes a rotor winding (113, 213, 350, 450, 513). The WRIG also includes a stator winding (112, 212a-212b, 300, 400, 420, 512a-512c, 612a-612c, 712a-712c) electrically connected to a utility source (130, 230, 530a-530b, 630a-630b, 730) and a load (160, 260, 560, 660). When the stator winding receives first power from the utility source, the WRIG is configured to transform at least one of a voltage and a frequency of the first power before outputting at least a portion of the first power to the load. When the stator winding does not receive the first power from the utility source, the WRIG is configured to generate second power due to kinetic energy of the rotor and output at least a portion of the second power to the load.
Patent WO-2021216782-A1 (WO)
Title: Systèmes et procédés de commande de flexion à degrés de liberté multiples et de la longueur de courbure d'un fil-guide orientable de manière robotisée aligné coaxialement
Inventor: DESAI JAYDEV P
IPC: A61B34/35
Filed: 2021-04-21
Abstract: La présente divulgation se rapporte d'une manière générale à des systèmes et à des procédés de commande de fil-guide, et en particulier à des systèmes et à des procédés pour la commande de la flexion à degrés de liberté multiples et de la longueur de courbure d'un fil-guide orientable de manière robotisée aligné coaxialement. La présente divulgation est actionnée manuellement, et autrement, est actionnée de manière automatique/robotisée.
Patent WO-2021216802-A1 (WO)
Inventor: MICALLEF CHRISTOPHER
IPC: F04B49/06
Filed: 2021-04-22
Abstract: Certain example embodiments provide a vapor compression refrigeration system, comprising: a compressor configured to suction refrigerant at a low pressure and temperature from a suction return, compress the refrigerant, and output refrigerant at a higher pressure and temperature; a condenser configured to cool refrigerant received from the compressor as the refrigerant passes though coils in the condenser; an expansion device configured to reduce the pressure of the refrigerant received from the condenser; and an evaporator configured to allow the refrigerant received from the expansion device to absorb heat surrounding the evaporator. The system may include a plurality of sensors configured to measure temperature of the system and a controller configured to control, based on the signals from one or more sensors, operation of the compressor and/or an evaporator fan motor configured to allow the refrigerant received from the expansion device to absorb heat surrounding the evaporator.
Patent WO-2021217079-A1 (WO)
Title: Systèmes et procédés de routage de fibres
Inventor: CLAESEN JEROEN
IPC: G02B6/44
Filed: 2021-04-23
Abstract: La présente invention concerne des systèmes et des procédés de gestion de fibres pour faciliter l'assemblage de dispositifs à fibres optiques d'une manière efficace en permettant à des fibres optiques pré-traitées et testées d'être pré-acheminées sur un substrat avant l'installation dans leurs dispositifs à fibres optiques correspondantes.
Patent WO-2021231578-A1 (WO)
Title: Small data transmission
Inventor: KIM TAEHUN
IPC: H04W76/27
Filed: 2021-05-12
Abstract: A wireless device is in a radio resource control non-connected state. The wireless device transmits, to a base station, first data associated with a small data transmission procedure and an RRC request message. While the wireless device is in the RRC non-connected state, the wireless device receives, from the base station, an indication of an uplink resource and transmits, via the uplink resource, second data associated with the SDT procedure. While the wireless device is in the RRC non-connected state, the wireless device receives, from the base station and after the transmitting the second data, an RRC release message.
Patent WO-2021236490-A1 (WO)
Title: Compatibilization of immiscible polymers using carbon nanotubes
Inventor: HART ASHLEY
IPC: C01B32/156
Filed: 2021-05-17
Abstract: The present disclosure provides a polymer blend that includes at least two polymers which are immiscible to one another and a carbon nanotube pulp comprising entangled carbon nanotubes as a compatibilizing agent and to a method of preparing the same.
Patent WO-2021237172-A1 (WO)
Title: Ultraviolet air sterilizer
Inventor: OBERMEYER HENRY K
IPC: A61L9/20
Filed: 2021-05-21
Abstract: The present invention discloses improved ultraviolet air sterilizers. In accordance with this invention the mean reflected light path of each photon is maximized while turbulence is suppressed in order to uniformly UVC expose all conveyed pathogen particles. This invention discloses novel means of maximizing the utilization of blower power and UVC lamp power toward the destruction of pathogens. The resulting efficiencies facilitate the construction of high flow rate air sterilization systems for large buildings while also facilitating the miniaturization of UVC air sterilization systems for incorporation into personal protective equipment (PPE).
Patent WO-2021257674-A1 (WO)
Title: A self-cleaning porous layer to minimize thrombus formation on blood contacting devices
Inventor: VANDE GEEST JONATHAN
IPC: A61F2/04
Filed: 2021-06-16
Abstract: The invention relates to self-cleaning porous structures, e.g., layers or coatings, fabricated within, applied to, or deposited on a blood contacting surface of a medical device, to prevent activation and aggregation of platelets thereon. In certain embodiments, the layer or coating is composed of multi-layered fibers. The porous structure is fabricated within, applied to, or deposited on, such as to form a permeable wall on the blood contacting surface. The blood travels into the wall and subsequently back out (reversing back into the lumen) during a cardiac cycle. Reversal flow is controlled during the diastole phase such that the backward flow repels the platelets and prevents their activation and aggregation and therefore, minimizes thrombus formation.
Patent WO-2022026163-A1 (WO)
Inventor: GUNDERSON BRUCE D
IPC: G16H50/30
Filed: 2021-07-12
Abstract: Techniques are disclosed for detecting when a patient is experiencing seasonal affective disorder (SAD). An example computer-implemented method includes determining a status of one or more health metrics for a patient based on sensor data collected from at least one biometric device. The method also includes determining potential sun exposure for a patient based on weather metrics corresponding in time with the health metrics. Additionally, the method includes, when a decline in the status of the health metrics for the patient correlates with declining potential sun exposure, providing an alert indicative that patient is experiencing SAD.
Patent WO-2022026420-A1 (WO)
Inventor: Wang qing peng
IPC: H01L21/67
Filed: 2021-07-26
Abstract: A system, method, and/or non-transitory computer readable medium may implement or be configured to implement the following computational operations associated with electrochemical or vapor phase deposition: (a) defining an interface of a substrate where deposition of a deposited material is to occur or is occurring; (b) using a computational model of the deposition to determine a local deposition rate of the deposited material at multiple locations on the interface, where the computational model of the deposition computes the local deposition rate as a function of one or more geometric parameters of the one or more recessed or protruding features; and (c) computationally adjusting the location of the interface to produce an adjusted interface.
Patent WO-2022036314-A1 (WO)
Inventor: DIXON JEFFERSON
IPC: G02B6/27
Filed: 2021-08-16
Abstract: Self-isolated lasers are provided by using a chiral metasurface in combination with a spin-selective gain medium and symmetry-breaking (i.e., not linearly polarized) optical pumping. In preferred embodiments the chiral metasurface is resonant, thereby proving an integrated optical resonator to support lasing. The chiral metasurface can be the spin- selective gain medium, or it can be formed on a surface of the spin-selective gain medium, or it can be distinct from the spin-selective gain medium.
Patent WO-2022047233-A1 (WO)
Title: Self-managed trust in internet of things networks
Inventor: LEE SOO BUM
IPC: G06F21/57
Filed: 2021-08-27
Abstract: Apparatus, methods, and computer-readable media for facilitating self-managed trust in Internet-of-Things networks are disclosed herein. An example method of trust management at a network manager includes enrolling a network endpoint with a network managed by the network manager. The example method also includes receiving trusted reference information for the network endpoint based on enrolling the network endpoint. Additionally, the example method includes performing verification of the network endpoint based on at least one of the trusted reference information or an attestation received from the network endpoint. Further, the example method includes enforcing policies to the network endpoint based on a result of the verification. Such trust management may improve privacy and security at the network, as well as reduce latency in responding to trust incidents.
Patent WO-2022060842-A1 (WO)
Title: Systems and methods for predicting graft dysfunction with exosome proteins
Inventor: FINE BARRY
IPC: A61P11/00
Filed: 2021-09-15
Abstract: The present subject matter relates to techniques for identifying risk of primary graft dysfunction (PGD) of a subject. The disclosed method can include collecting serum of the subject, measuring a level of a PGD marker from the serum, wherein the PGD marker comprises plasma kallikrein (KLKB1), providing a PGD risk value that is quantified based on the level of the PGD marker using an adaptive Monte Carlo cross-validation (MCCV) model, and identifying the risk of PGD based on the PGD risk value.
Patent WO-2022072560-A1 (WO)
Title: Lieurs de terminaisons polypeptidiques et leurs utilisations
Inventor: GANGULY SOUMYA
IPC: G01N33/68
Filed: 2021-09-29
Abstract: La présente invention concerne un lieur qui se lie spécifiquement à un polypeptide modifié au niveau de la terminaison N par l'interaction avec un acide aminé modifié au niveau de la terminaison N. L'invention concerne également un procédé et des kits associés pour traiter un polypeptide à l'aide du lieur ou comprenant le lieur et/ou une clivase modifiée. L'invention concerne également un procédé et des kits associés pour transférer des informations en utilisant une pluralité d'enzymes, y compris pour réaliser une réaction de ligature, d'extension et de clivage avec des molécules d'acide nucléique associées au polypeptide pour l'analyse.
Patent WO-2022081672-A1 (WO)
Title: Transistors électrochimiques organiques flexibles en tant que capteurs de flexion
Inventor: KAPHLE VIKASH
IPC: C08G61/00
Filed: 2021-10-13
Abstract: Des transistors électrochimiques organiques (OECT) ont le potentiel de permettre une électronique entièrement flexible à faible coût. La combinaison d'OECT avec des polymères électroactifs ioniques (IEAP) permet d'obtenir des capteurs de flexion hautement sensibles par rapport à la flexion mécanique. En comparaison, le capteur proposé présente une sensibilité qui est de plusieurs ordres de grandeur supérieure par comparaison avec les polymères électroactifs classiques.
Patent WO-2022098842-A1 (WO)
Inventor: GLEDHILL ANDREW
IPC: B22F5/00
Filed: 2021-11-04
Abstract: Un corps en carbure de tungstène cémenté est formé par un mélange, l'une avec l'autre, d'une poudre de carbure de tungstène et d'une poudre de cobalt pour former un mélange de poudres. La poudre de carbure de tungstène constitue au moins 80 pour cent en poids du mélange de poudres, tandis que la poudre de liant de cobalt constitue environ de 1,5 pour cent en poids à environ 20 pour cent en poids du mélange de poudres. Le mélange de poudres est ensuite compacté pour former un comprimé en cru, et un revêtement de nitrure de bore est appliqué sur une surface du comprimé en cru pour former un comprimé enrobé. Le comprimé enrobé est fritté à une température suffisante pour faire fondre la poudre de cobalt, de sorte que le bore du revêtement de nitrure de bore se diffuse dans le comprimé et crée un gradient de cobalt métallique et de bore s'étendant vers l'intérieur à partir de la surface. La teneur en cobalt métallique augmente de la surface vers l'intérieur, tandis que la teneur en bore diminue de la surface vers l'intérieur.
Patent WO-2022099068-A1 (WO)
Inventor: SLAGMOLEN PIETER
IPC: G06T7/73
Filed: 2021-11-05
Abstract: Certains modes de réalisation de la présente invention concernent un système d'étalonnage d'une image radiographique. Le système peut recevoir une image radiographique d'une partie anatomique d'un patient. Le système peut en outre recevoir un balayage de surface 3D d'une surface du patient où la partie anatomique est située. Le système peut dériver une correction de mesure à appliquer à des mesures de l'image radiographique sur la base du balayage de surface 3D. La correction de mesure peut prendre en compte : une orientation du patient par rapport à la plaque de détection de rayons X, une première distance entre le patient et la plaque de détection, ou une seconde distance entre le patient et une source de rayons X utilisée pour générer l'image radiographique. Le système peut en outre déterminer une mesure corrigée de la partie anatomique sur la base de la correction de mesure et d'une mesure prise à partir de l'image radiographique.