baber/WOPTO huggingface dataset:
Patent SI-1652857-T1 (SI)
Title: Fusion protein of HIV regulatory/accessory proteins
Inventor: HOWLEY PAUL
IPC: A61K39/00
Filed: 2003-05-14
Abstract: The invention relates to fusion proteins comprising the amino acid sequence of at least four HIV proteins selected from Vif, Vpr, Vpu, Rev, Tat and Nef or derivatives of the amino acid sequence of one or more of said proteins, wherein the fusion protein is not processed to individual HIV proteins having the natural N and C termini. The invention further concerns nucleic acids encoding said proteins, vectors comprising said nucleic acids, and methods for producing said proteins. The fusion protein, nucleic acids and vectors are usable as vaccines for the at least partial prophylaxis against HIV infections.
Patent SI-1496870-T1 (SI)
Title: Dosage form and method for producing the same
Inventor: PETEREIT HANS-ULRICH
IPC: A61K9/00
Filed: 2004-03-02
Abstract: The invention relates to a process for producing a coated drug form or a drug form in the form of an active ingredient matrix, by processing a copolymer, an active pharmaceutical ingredient, a core if present and/or pharmaceutically customary excipients in a conventional manner by melting, injection molding, extrusion, wet granulation, casting, dipping, spreading, spraying or compression to form a coated drug form and/or to form an active ingredient matrix, characterized in that a copolymer is used which is composed of 20 to 33% by weight methacrylic acid, 5 to 30% by weight methyl acrylate, 20 to 40% by weight ethyl acrylate and more than 10 to 30% by weight butyl methacrylate and, if desired, 0 to 10% by weight further vinylically copolymerizable monomers, with the proviso that the glass transition temperature of the copolymer in accordance with ISO 11357-2, section 3.3.3, is 55 to 70° C. The invention further relates to the drug form produced in accordance with the invention, to the copolymer, and to the use thereof.
Patent SI-2311434-T1 (SI)
Title: Dry powder inhaler formulations comprising surface-modified particles with anti-adherent additives
Inventor: MORTON DAVID
IPC: A61K9/00
Filed: 2005-11-23
Abstract: The present invention is concerned with a refinement of the processing of particles that are to form a dry powder formulation which is to be administered to the lung using a dry powder inhale (DPI) device In particular, the present invention provides the processing of particles of active material and particles of carrier material in the presence of additive material to provide a powder composition which exhibits excellent powder properties and which is economical to produce.
Patent SI-1858861-T1 (SI)
Title: Hiv inhibiting 2-(4-cyanophenyl)-6-hydroxylaminopyrimidines
Inventor: DE KOCK HERMAN AUGUSTINUS
IPC: A61K31/505
Filed: 2006-03-02
Abstract: HIV replication inhibitors of formula pharmaceutically acceptable addition salts; or stereochemically isomeric forms thereof, wherein R1 is halo; R2 and R3 each independently are C1-6alkyl; pharmaceutical compositions containing these compounds as active ingredient and processes for preparing these compounds and compositions.
Patent SI-2484346-T1 (SI)
Title: Pharmaceutical compositions
Inventor: MATTHEWS FRANK
IPC: A61K9/00
Filed: 2007-06-19
Abstract: Provided herein is a pharmaceutical composition comprising an antagonist, an agonist, a seal coat, and a sequestering polymer, wherein the antagonist, agonist, seal coat and at least one sequestering polymer are all components of a single unit, and wherein the seal coat forms a layer physically separating the antagonist from the agonist from one another. Methods for manufacturing such a pharmaceutical composition are also provided.
Patent SI-2024499-T1 (SI)
Title: Oligonucleotide analogs having cationic intersubunit linkages
Inventor: WELLER DWIGHT D
IPC: C07H21/00
Filed: 2007-05-10
Abstract: Morpholino oligomers containing both uncharged and cationic intersubunit linkages are provided. The oligomers are oligonucleotide analogs containing predetermined sequences of base-pairing moieties. The presence of the cationic intersubunit linkages in the oligomers, typically at a level of about 10-50% of total linkages, provides enhanced antisense activity, in various antisense applications, relative to the corresponding uncharged oligomers. Also provided are such oligomers conjugated to peptide transporter moieties, where the transporters are preferably composed of arginine subunits, or arginine dimers, alternating with neutral amino acid subunits.
Patent SI-2387194-T1 (SI)
Title: Apparatus for transmitting and receiving a signal and method for transmitting and receiving a signal
Inventor: KO WOO SUK
IPC: H04L1/00
Filed: 2009-06-03
Abstract: The present invention relates to method of transmitting and a method of receiving signals and corresponding apparatus. One aspect of the present invention relates to a layer 1 (L1) signaling and a receiver using the L1 signaling for efficient cable broadcasting.
Patent TR-200001998-T1 (TR)
Title: Kontrollü salıverilen tolterodin uygulamak için ilaç formülasyonu
Inventor: NILVEBRANT LISBETH
IPC: A61K/
Filed: 1999-08-26
Abstract: Kararsiz ya da asiri etkin idrar kesesini tedavi etmeye yönelik bir yöntem ve formülasyon; sözkonusu yöntemde, bir hastaya, kontrollü saliverme saglayan bir formülasyon araciligiyla, tedavi etme bakimindan etkili bir miktaarda tolterodin ya da tolterodin ile baglantili bir bilesik ya da bunun ilaç sanayiinde kullanilmaya uygun bir tuzu uygulanmaktadir; burada sözkonusu formülasyon tolterodin ya da adi geçen tolterodin ile baglantili bilesigi ya da adi geçen tolterodin ile baglantili bilesigi ya da bunun tuzunu, en az 24 saat boyunca, kontrollü bir oranda uygulanmaktadir.
Patent TR-200101223-T1 (TR)
Inventor: HILLIER PAUL V
IPC: H04L12/64
Filed: 2000-08-30
Abstract: A local communication system comprises a first cluster ( 10 ) of devices interconnected for the communication of messages via a first data bus ( 18 ) and in accordance with a first set of communication protocols, a second cluster ( 20 ) interconnected via a second data bus ( 28 ) and following the first set of communication protocols; and a data channel ( 41 ) linking a device ( 19 ) of the first cluster ( 10 ) and a device ( 29 ) of the second cluster ( 20 ). The data channel ( 41 ) suitably comprises an RF link supporting communication of messages in accordance with a second set of communications protocols. A device ( 19 ) of the first cluster ( 10 ) holds a stored software representation of operational features of a selected device (DVHS- 2 ) of the second cluster ( 20 ) and any device ( 11 ) of the first cluster wishing to interact with said selected device (DVHS- 2; 22 ) instead interacts with said stored representation.
Patent DE-3779813-T2 (DE)
Inventor: SEMERARO CLAUDIO
IPC: C07D211/90
Filed: 1987-02-19
Granted: 1992-12-24
Abstract: Compounds are described of the formula <CHEM>  wherein  R1 and R4 independently represent a C1-4 alkyl group; R2 and R3 independently represent a C1-6 straight or branched alkyl chain or alkoxy group; R5 represents a straight or branched chain C1-13 alkyl group or a C5-8 cycloalkyl group which may be substituted by a C1-3 alkyl substituent; R6 represents a halogen atom or a straight or branched C1-3 alkyl group. R7 represents a C1-4 alkyl group [optionally substituted by hydroxy, C1-3 alkoxy or trifluoromethyl or by a group NR8R9 where NR8R9 forms a saturated 5 to 7 membered ring optionally containing an additional heleroatom which is oxygen]; or R7 represents a phenyl C1-2 alkyl group in which the phenyl portion is optionally substituted by 1 to 3 C1-3 alkyl or C1-3 alkoxy groups or halogen atoms. The compounds represented by formula (I) reduce intracellular calcium ion concentration by limiting transmembranal calcium ion influx and thus may be useful for the treatment of cardiovascular disorders such as hypertension.
Patent DE-3786798-T2 (DE)
Inventor: TUUNANEN ARNE
IPC: A01L/
Filed: 1987-04-16
Granted: 1994-03-31
Abstract: PCT No. PCT/SE87/00197 Sec. 371 Date Dec. 5, 1988 Sec. 102(e) Date Dec. 5, 1988 PCT Filed Apr. 16, 1987 PCT Pub. No. WO87/06097 PCT Pub. Date Oct. 22, 1987.A horseshoe (1) conformed substantially to the U-shaped sole of the hoof and having a reinforcing insert (16) of a flexible and, alternatively, partially curable material and a portion (17) which encloses the insert (16) and is made of an elastic friction material. The insert (16) is narrower than the width of the U-shaped sole such that thrust, shock and shear loads generated as the horse moves at a walking, trotting or galloping pace are elastically absorbed by the portion (17) enclosing the insert. The insert (16) comprises four surfaces extending along the entire shoe, at least three of which, the lower, the outer and the inner one (9), are provided with longitudinal grooves (10, 11, 18), the lower groove (18) preferably having a tapering cross-section to receive and guide the tapered nails for attaching the shoe, and the grooves (10, 11) in the outer and inner surfaces (9) serving on the one hand to increase the total surface area of the insert and make the vulcanisation surface thereof larger and, on the other hand, to make the finished shoe more easily adjustable.
Patent DE-3850421-T2 (DE)
Inventor: CAIN FREDERICK WILLIAM
IPC: A23D7/015
Filed: 1988-02-16
Granted: 1994-10-20
Abstract: The present invention is concerned with an edible, plastified dispersion containing less than 35 wt.% fat, which comprises from 10 to 35 wt.% continuous fat phase and from 90 to 65 wt.% dispersed aqueous phase, said dispersed aqueous phase having an average droplet size, indicated by the number weighted mean diameter, of less than 5 mu m, which dispersion comprises less than 0.1 wt.% amino acid residues. The low-calorie products according to the invention are stable at ambient temperature and under spreading conditions, and have favourable organoleptic properties. Another aspect of the present invention concerns a process for preparing an edible plastified dispersion, comprising:   (a) mixing oil and water so as to obtain an oil- and water-containing emulsion, comprising from 15-28 wt.% fat, from 85-72 wt.% water, and less than 0.1 wt.% of amino acid residues; (b) cooling at least part of the oil, the water or the mixture of oil and water; and (c) working the oil- and water-containing emulsion under such conditions that an oil-continuous phase is formed, and the number weighted mean diameter of the dispersed aqueous phase droplets is less than 5 mu m. t
Patent DE-3850583-T2 (DE)
Inventor: BIGLIONE GIANFRANCO
IPC: C08L51/06
Filed: 1988-02-04
Granted: 1994-12-01
Abstract: Blends based on vinyl-aromatic polymers endowed with improved characteristics of chemical resistance, comprising: -- from 10% to 90% by weight of an impact-resistant styrenic copolymer containing from 8 to 30% by weight of an ethylenically unsaturated nitrile, from 15% to 45% by weight of an olefinic elastomer, and from 77% to 25% by weight of a vinyl-aromatic monomer, and -- from 90% to 10% by weight of a mixture of aromatic group containing resins constituted by from 70% to 99% by weight of an aromatic polycarbonte and from 30% to 1% by weight of an aromatic polyester.
Patent DE-3855508-T2 (DE)
Inventor: LEE GUO-SHU JOHN
IPC: C07C39/17
Filed: 1988-11-18
Granted: 1997-03-27
Abstract: Aromatic compounds, such as benzene or biphenyl, are alkylated with an alkylating agent, such as propylene, in the presence of an acidic mordenite zeolite catalyst under conditions sufficient to produce a mixture of substituted polycyclic aromatic compounds enriched in the para alkylated isomers, such as p-diisopropyl-benzene or p,p min -di(isopropyl)biphenyl, respectively. The novel acidic mordenite catalyst is characterized by its silica/alumina molar ratio, its porosity, and Symmetry Index. The p,p min -disubstituted isomers of aromatic compounds are useful as monomers in the preparation of thermotropic, liquid crystal polymers.
Patent DE-3875927-T2 (DE)
Inventor: KAMATA SUSUMU
IPC: A61K31/635
Filed: 1988-12-16
Granted: 1993-03-25
Abstract: Lipid derivatives represented by the formula: <CHEM> wherein R1 is alkyl or alkylcarbamoyl; R2 is lower alkyloxy, lower alkylcarbamoyloxy, lower alkylcarbonylamino, lower alkyloxycarbonylamino, lower alkylureido, lower alkyloxymethyl, lower alkylcarbonylmethyl, cyanomethyl, heterocyclic group, or heterocyclyloxy; R2 min  is hydrogen or R2 and R2 min  taken together form -O(CH2)m- wherein m is an integer of 1 to 5; R3, R4, and R5 each is hydrogen or lower alkyl or two or three of R3, R4, and R5 taken together with the adjacent nitrogen atom form cyclic ammonio; R5 is hydrogen or lower alkylcarbonyl; X<-> is a counter anion; Y is oxygen or sulfur; and n is an integer of 1 to 10, being useful as PAF antagonists, e.g., as antithrombotic, antivasoconstricting, antibronchoconsticting agent or antitumor agent.
Patent DE-3883323-T2 (DE)
Inventor: WU BOR-TAY
IPC: H03K19/003
Filed: 1988-06-15
Granted: 1994-02-24
Abstract: An output buffer includes a pull-up transistor (N1), a first pull-down transistor (N3), a second pull-down transistor (N8), and a logic circuit (15). The logic circuit (15) is responsive to a data input signal making a high-to-low transition and the output signal making a high-to-low transition for maintaining the second pull-down transistor (N8) turned-off until after an output node has made the high-to-low transition, thereby reducing significantly the ground bounce noise.
Patent DE-3886280-T2 (DE)
Inventor: MOELLGAARD HENRIK
IPC: C22B3/00
Filed: 1988-06-30
Granted: 1994-03-31
Abstract: Immobilization method comprising mixing with polyazetidine, dewatering, sub-dividing and curing. The method is useful for enzymes, cell mass, coenzymes and antibodies. The product is physically strong, and less cross-linking agent can be used than in prior-art processes.
Patent TR-199900312-T2 (TR)
Inventor: VERNOOIJ BARNARDUS THEODORUS M
IPC: A01N63/02
Filed: 1997-08-13
Abstract: Laktoferisinin bitki patojenlerine karsi anti mantarsal etkiye sahip oldugu saptanmistir. Büyükbas hayvanlarla ilgili laktoferrisin için sentetik bir jen ihtiva eden jenetik tertipler hazirlanir ve transjenik hastaliga dirençli bitkilerin saglanmasi için kullanilir. Bitkilerdeki hastalik direncinin saglanmasinda bosaltilan laktoferrisini tarif etmek için bitkilerin biçimini degistiren bir yöntem ayrica açiklanir.
Patent DE-60003455-T2 (DE)
Inventor: PIERRE LUDOVIC
IPC: H04N7/24
Filed: 2000-09-15
Granted: 2004-05-06
Abstract: A method for playing back a program which includes one or more interactive applications. A program which is stored, either in the form of a data stream or as a set of files is played back from a storage device. When playback is started, applications which are detected are launched. Applications are detected in the playback of pushed content when they become available in the playback stream. Applications are detected in the playback of pulled content by comparing the validity ranges of the applications to a current playback index. When special playback modes are used, signals which affect the lifecycle of an application are detected and corresponding signals are generated to maintain the proper state of the application. During these special playback modes, these various notification signals may be conveyed to applications which are configured to operate during these modes. Applications which are not configured to operate during these special playback modes may be terminated when the special modes are initiated and restarted when the special modes end.
Patent DE-60006280-T2 (DE)
Inventor: MORAN J
IPC: A61P/
Filed: 2000-12-06
Granted: 2004-07-29
Abstract: Disclosed are multibinding compounds which are  beta 2 adrenergic receptor agonists and are useful in the treatment and prevention of respiratory diseases such as asthma, bronchitis. They are also useful in the treatment of nervous system injury and premature labor.
Patent DE-60010318-T2 (DE)
Inventor: CHYI L
IPC: B03B9/04
Filed: 2000-10-06
Granted: 2005-02-17
Abstract: The present invention, therefore, provides stage crushing method for recovering precious metals from slag produced by a coal burning furnace or boiler comprising: a plurality of crushing steps, wherein each crushing step produces slag particles having successively smaller particle diameter sizes, said crushing steps continued until a final desired particle diameter sized is obtained; wherein each of said crushing steps is followed by suspending said crushed slag particles in a liquid medium to form a slurry of light-weight particles and heavy weight-particles and allowing the crushed slag particles within the slurry to separate, based on weight of the particles, thereby forming a light-weight particle population and a heavy-weight particle population; wherein each suspending step is followed by removing said light-weight particles from said slurry, such that said slurry consists of substantially heavy-weight particles; and collecting said heavy-weight particles.
Patent DE-60019317-T2 (DE)
Inventor: MORTLOCK ANDREW AUSTEN
IPC: C07D401/12
Filed: 2000-09-18
Granted: 2006-03-09
Abstract: A compound of formula (I) or a salt, ester or amide thereof; where X is O, or S, S(O) or S(O)<SUB>2 </SUB>or NR<SUP>10 </SUP>where R<SUP>10 </SUP>is hydrogen or C<SUB>1-6 </SUB>alkyl, and R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP>, R<SUP>6</SUP>, R<SUP>7</SUP>, R<SUP>8 </SUP>and R<SUP>9 </SUP>are various specified organic groups. These compounds are inhibitors of aurora 2 kinase, and are useful in the treatment of cancer.
Patent DE-60019364-T2 (DE)
Inventor: SCHERZER HELMUT
IPC: G06F11/14
Filed: 2000-02-29
Granted: 2006-03-09
Abstract: The basic idea comprised of the present invention is to provide two sets of descriptors having each at least three descriptors and each set is used in an alternating manner for defining the location of source and target of the copy operations which are to be performed during the defragmentation procedure. The defragmentation procedure is performed as a sequence of copy operations on copy chunks, i.e., a certain number of sequentially arranged bytes to be copied being part of a valid data block to be copied. In each of said copy operations in said sequence the values which are assigned to said descriptors Change. According to a characterizing feature of the present invention during the whole sequence of copy operations comprised of the defragmentation process one of the two sets of descriptors holds information which is usable for restoring the contents of a copy chunk in case of a power break during a copy operation on said copy chunk. Thus, defragmenting is a safe procedure, and data integrity is assured.
Patent DE-60023242-T2 (DE)
Inventor: BECHERUCCI RAFFAELE
IPC: H02K15/02
Filed: 2000-11-02
Granted: 2006-07-27
Abstract: Methods and apparatus are provided for wire winding and fabrication for dynamo-electric machine components such as ferromagnetic armature or stator cores for motors or the like. Wire may be wound onto individual portions of dynamo-electric machine components, which may then be assembled to form complete components. Wire may be wound by steering a rotating flyer or the like in a trajectory that closely follows the surface of the core onto which the wire is being wound. Wire may also be wound by rotating the portions during winding. The same holding members that are used to hold the portions during winding may be used to hold the portions during assembly of the portions into machine components. <IMAGE>
Patent DE-60025374-T2 (DE)
Inventor: CHIARI MARCELLA
IPC: C12Q1/6869
Filed: 2000-08-21
Granted: 2006-09-14
Abstract: The instant invention describes uncharged water-soluble polymers to suppress electroosmotic flow in capillary electrophoresis. The polymers in the instant invention are copolymers of various derivatives of acrylamide and methacrylamide monomers with various glycidyl group containing monomers e.g., dimethylacrylamide and allyl glycidyl ether-epoxy poly(DMA)-, copolymers of various derivatives of acrylamide and methacrylamide with various allyl group containing carbohydrates and various glycidyl group containing monomers, such as allyl beta-D-pyranoside (typically beta-D-glucopyranoside) or allyl beta-D-furanoside, allyl glycidyl ether-epoxy poly(AG-AA) and copolymers of four different monomers including various acryl and methacrylamide, various allyl group containing carbohydrates, various glycidyl group containing monomers and various diol group containing monomers, such as acrylamide, allyl beta-D-pyranoside (typically beta-D-galactopyranoside or N-allylgluconamide) or allyl beta-D-furanoside, allyl glycydyl ether and allyoxy-1,2 propanediol-epoxy poly(AGal-AA-APD). The subject polymers adsorb onto the capillary surface, forming a highly hydrophilic, dynamic coating that suppresses electroosmotic flow. The subject polymers may be used as a coating prior to use of an electrophoresis microchannel or may be included in a separation media contained within the capillary column. The instant coatings and media are especially suitable for applications pertaining to the electrophoretic separation of various biomolecules, such as protein and DNA.
Patent DE-60027870-T2 (DE)
Inventor: WEICHSELBAUM RALPH
IPC: A61K35/763
Filed: 2000-02-04
Granted: 2006-12-28
Abstract: Disclosed are methods for treating cancer by administering an effective amount of a modified Herpes simplex virus.
Patent DE-60034295-T2 (DE)
Inventor: AL-ZAHRANI SAEED M DR
IPC: C07C5/48
Filed: 2000-08-25
Granted: 2008-01-03
Abstract: A new catalyst system is disclosed for the production of olefins through oxidative dehydrogenation of hydrocarbons. The catalyst system having the atomic ratios described by the empirical formula Bia NiOb/Al2O3.
Patent DE-60035339-T2 (DE)
Inventor: WOLF JAY B
IPC: H04L12/26
Filed: 2000-04-10
Granted: 2008-03-06
Abstract: A method for collecting and reporting monitored data for network traffic, which has been accumulated by a plurality of remote probes. The method includes making a series of polling requests for lists of monitoring data to each probe and receiving the requested lists. Each list has traffic count values that are identified by at least a sampling time, a source address, a destination address and a probe identifier. The method also includes calculating the traffic observed by each probe between successive sampling times and apportioning the calculated traffic data among a single set of consecutive temporal intervals and selecting best counts to avoid overcounting.
Patent DE-60035913-T2 (DE)
Inventor: IINO KOJI
IPC: B60H1/26
Filed: 2000-01-20
Granted: 2008-05-15
Abstract: A ventilation system for a car window comprising a body housing 11, blocking plates A (13) and B (14'), and a plurality of airflow members (18, 19, 20, 21 and 55), wherein: the plurality of airflow members (18, 19, 20, 21, 55) are arranged in layers in an inner chamber following a ventilation opening 11a of the body housing (11); and a cover plate (56) which can be opened/closed to adjust the quantity of air flowing through all the airflow members (18, 19, 20, 21 and 55) is provided on a cover frame (52) to which the innermost airflow member (55) is attached, whereby a ventilating function is given to the car window so that the quantity of air flowing through the car window can be adjusted at option. <IMAGE>