baber/WOPTO huggingface dataset:
Patent CA-2381129-A1 (CA)
Title: Flexible needle assembly
Inventor: DIBIASI MICHAEL A
IPC: A61M5/32
Filed: 2002-04-09
Abstract: An apparatus and method of providing a flexible needle assembly for use with a medication delivery pen. The flexible needle assembly includes a needle cannula haying proximal and distal points and a hub coupled to the needle cannula. The hub includes a flexible roof, or ball-and-socket arrangement, that permits the needle cannula to move about the centerline of the hub. The flexible roof can include one or more concentric ribs to enhance flexibility of the needle cannula about the centerline of the hub.
Patent CA-2382031-A1 (CA)
Title: Method for producing prepolymers containing isocyanate end groups, incorporating a small proportion of base isocyanates
Inventor: BARNES JAMES-MICHAEL
IPC: C08G18/10
Filed: 2000-08-11
Abstract: The invention relates to a method for producing prepolymers containing isocyanate end groups from polyester polyols and poly-isocyanates. Said prepolymers incorporate a small proportion of free base isocyanates.
Patent CA-2382142-A1 (CA)
Inventor: GUERET JEAN-LOUIS
IPC: A46D1/00
Filed: 2001-06-19
Abstract: L'invention concerne un dispositif de conditionnement et/ou d'application d' un produit cosmétique et/ou de soins, comprenant des fibres comportant au moins  un corps aimanté ou aimantable.
Patent CA-2382495-A1 (CA)
Title: Secreted and transmembrane polypeptides and nucleic acids encoding the same
Inventor: PENNICA DIANE
IPC: A61P31/12
Filed: 1998-09-16
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptides molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Patent CA-2384565-A1 (CA)
Title: Targeting multimeric imaging agents through multilocus binding
Inventor: AMEDIO JOHN
IPC: A61K49/00
Filed: 2000-07-28
Abstract: The present invention relates to contrast agents for diagnostic imaging. In particular, this invention relates to novel multimeric compounds which exhib it improved relaxivity properties upon binding to endogenous proteins or other physiologically relevant sites. The compounds consist of: a) two or more Ima ge Enhancing Moieties (IEMs) (or signal-generating moiety) comprising multiple subunits; b) two or more Target Binding Moieties (TBMs), providing for in vi vo localization and multimer rigidification; c) a scaffold framework for attachment of the above moieties; and d) optional linkers for attachment of the IEMs to scaffold. This invention also relates to pharmaceutical compositions comprising these compounds and to methods of using the compound s and compositions for contrast enhancement of diagnostic imaging.
Patent CA-2384965-A1 (CA)
Inventor: BRENNER NATS A
IPC: B64D45/04
Filed: 2000-09-14
Abstract: A cause de leur manque de précision et de fiabilité, les systèmes GPS n'ont traditionnellement pas été utilisés pour les phases critiques du guidage aérien et de la navigation aérienne telles que les atterrissages. Par conséquent, la présente invention consiste en un système GPS au sol renforcé comprenant un procédé amélioré permettant de déterminer la précision des solutions de positions. Un mode de réalisation consiste à déterminer une solution de position principale et une ou plusieurs sous-solutions de position; la solution principale faisant appel à toutes les données de correction d'émission et chaque sous-solution utilisant un sous-ensemble de données de correction respectif. Les différences ou les séparations entre la solution de position principale et les sous-solutions sont alors utilisées de manière à déterminer la précision ou la protection, les limites de la solution de position principale. Un autre mode de réalisation utilise les filtres de Kalman pour intégrer les données de déplacement du véhicule dans le calcul de la solution principale et des sous-solutions; ce qui permet de déterminer les limites de protection pendant un temps de perte du GPS ou de données de correction.
Patent CA-2385924-A1 (CA)
Inventor: HUNIA ROBERT M
IPC: C09J133/02
Filed: 1997-09-22
Abstract: The present invention relates to an aircraft transparency including an electroconductive metal oxide coating over a rigid plastic substrate, and a polyurethane protective liner over the metal oxide coating, and more specifically to the use of a primer for adhering the metal oxide coating to the substrate and/or a primer for adhering the polyurethane protective liner to the metal oxide coating.      The metal oxide primer includes a carbonate diol-based crosslinked polyurethane. The polyurethane primer is selected from the group consisting of a crosslinked copolymer of acrylic acid and substituted acrylates such as 2-ethylhexylacrylate; a crosslinked copolymer of cyanoethylacrylate and acrylic acid; and a crosslinked terpolymer of 2-ethylhexylacrylate, cyanoethylacrylate and acrylic acid.
Patent CA-2386071-A1 (CA)
Inventor: ARIES MARIE-FRANCOISE
IPC: A61P17/00
Filed: 2000-09-29
Abstract: The invention concerns dry extracts of apple tree branches obtainable by extraction with a polar solvent from dried and crushed apple tree branches, followed by separation of the liquid phases from the solid phases, and then in producing a concentrate from the resulting products and drying the concentrate. The invention also concerns a method for preparing said extracts and their use in dermatology and cosmetology, in particular for inhibiting cell differentiation between pre-adipocytes and adipocytes and for slimming.
Patent CA-2390516-A1 (CA)
Inventor: FRISKEN STEVEN
IPC: G02B6/26
Filed: 2000-11-09
Abstract: A wavelength dependent optical device comprising: at least two optical Ports (21, 22); a first series of polarisation modifying optical components (23, 25, 27, 28) placed between the two Ports and a first dielectric mirror (29); the first dielectric mirror (29) operating substantially in reflectance mode at a first predetermined wavelength range and substantially in transmission mode at a second predetermined wavelength range; at least one second polarisation modifying optical component (30) placed between the first dielectric mirror (29) and a second mirror (31); the second mirror (31) operating substantially in reflectance mode at the second predetermined wavelength range; wherein light emitted from the first Port (21) at the first predetermined wavelength range is transmitted to the second Port (22), and light emitted from the first Port (21) at the second predetermined wavelength range is transmitted away from the second Port (22).
Patent CA-2393675-A1 (CA)
Inventor: MINEMOTO MASAYUKI
IPC: B22C9/06
Filed: 2001-09-17
Abstract: A mold cooling device comprises an air feeding and discharging circuit 22 which effects the driving by air of a pump section 1 for feeding a cooling liquid to a fluid flow passageway 65a formed in a mold 64 and the feeding of air to the fluid flow passageway 65a. Letting (Dx) be the outer diameter-corresponding dimension of the holed convex portion 53x of a cast article 64x, (D1) be the outer diameter of the pin section 65 of the mold 64, (t1) be the outer peripheral thickness of the pin section 65, and (T1) be -5.103 + (0.621 × Dx) - (1.068 × D1) + (3.61 × t1), the time (T) for feeding cooling liquid to the fluid flow passageway 65a after completion of the pouring of molten metal into the mold 64 is set so that the relation T1 - 0.5 seconds ~ T ~ T1 + 0.5 seconds is satisfied. Further, the central region of the bottom surface 67 in the bottom-closed cooling hole 66 formed in a mold 4 is formed with a flat surface portion 67a to which the front end opening in the inner pipe 62 is in opposed closely adjacent relationship, and the outer peripheral region of the flat surface portion 67a is formed with a curved surface portion 67b continuously extending from the flat surface portion 67a to the inner peripheral surface 66a of the bottom-closed cooling hole 66.
Patent CA-2396093-A1 (CA)
Title: Process and composition for controlling fecal hair excretion and trichobezoar formation
Inventor: DAVENPORT GARY M
IPC: A23K1/14
Filed: 2001-01-05
Abstract: A process and composition for controlling fecal hair excretion and trichobezoar formation in animals such as cats and rabbits is provided and includes feeding the animal a composition comprising from about 10 to about 42 wt% crude protein, from about 4 to about 30 wt% fat, from about 1 to about 25 wt% total dietary fiber, and a supplemental fiber source. The supplemental fiber source is present in amounts which provide from about 1 to about 13 weight percent of supplemental total dietary fiber. The animal is maintained on the diet for a sufficient period of time to control fecal hair excretion and trichobezoar formation.
Patent CA-2396850-A1 (CA)
Title: Volar fixation system
Inventor: LEONE JAMES
IPC: A61B17/17
Filed: 2001-01-29
Abstract: A volar fixation system (100) includes a T-shaped plate (102) intended to be positioned against the volar side of the radial bone, a plurality of bone screws (104) for securing the plate (102) along a non--fractured portion of the radial bone, and a plurality of bone pegs (108) which extend through the threaded pea holes (130, 132, 134 and 136) in the plate (102) and into bone fragments of a Colles' fracture. Various peg hole and peg arrangements are disclosed, including an embodiment in which the pegs (108) can be articulated through a range of angles within respective peg holes and fixed at a desired angle within the range.
Patent CA-2400868-A1 (CA)
Title: Anti-egfrviii scfvs with improved cytotoxicity and yield, immunotoxins based thereon, and methods of use thereof
Inventor: BIGNER DARELL
IPC: A61K47/48
Filed: 2001-02-23
Abstract: The invention provides antibodies to a mutant form of the epidermal growth factor receptor known as EGFRvIII found only or primarily on the surface of glioblastoma cells, and on cells of breast, ovarian and non-small cell lung carcinomas. The antibodies provided by the invention have the complementarity determining regions ("CDRs") of the scFv designated MR1, but with mutations at positions 98 and 99 in the CDR3 of the heavy chain variable region and, optionally, in other CDRs. In particular, the invention provides an antibody, designated MR1-1, which mutates MR1 in the CDR3 of the VH and VL chains. The invention provides additional antibodies in which MR1 is mutated in the CDR1 and 2 of VH or VL, or both.
Patent CA-2402617-A1 (CA)
Title: Swing arm
Inventor: HEAVEN JONATHAN MARK
IPC: B60B29/00
Filed: 2002-09-23
Abstract: A tool for loosening or tightening vehicle wheels nuts using a multiplying torque.        At one end of the main body there is a rotating shaft, the other end sits on the ground to create a resistance platform.        The rotating shaft has a nut socket on its end, which engages onto one of the wheel nuts. There is a lever arm parallel to the main body, connected perpendicular with a one directional ratchet system to the rotating shaft. The lever arms opposite end connects to a pry bar which rotates on a pin connected to the main body. When this pry bar is moved back and forth in a winching motion it causes the lever arm to go back and forth. This action in combination with the lever arm ratchet system will turn the rotating shaft in one direction creating multiplying torque on the wheel nut.
Patent CA-2404528-A1 (CA)
Inventor: DERBIN CLAUDE
IPC: A61P17/00
Filed: 2001-03-29
Abstract: The present invention provides peptides which can interact with VEGF and inhibit VEGF interaction with KDR or anti-VEGF antibody thereby inhibiting VEGF mediated angiogenesis or angiogeneis related diseases, polynucleotide encoding the peptides, vectors containing the polynucleotides, pharmaceutical compositions containing the peptides, and methods of inhibiting angiogenesis with the peptides.
Patent CA-2405334-A1 (CA)
Inventor: CHEN COLIN C
IPC: B32B15/04
Filed: 2002-09-26
Abstract: An improved heat shield offers thermal insulation and reduced noise transmission for vehicular engine components, including exhaust manifolds: The structure has three layers: an outer structural metal layer, a center insulation layer to isolate heat and dampen noise, and an inner metal layer directly adjacent the shielded component for reflecting heat back to the shielded component. As disclosed, the shield has at least one edge portion defined by outwardly flared undulations or waves. The waved edge minimizes impact of plastic deformation of the metal edges during manufacture of the shield, which tends to produce wrinkling at the edges, and creates undesirable stiffness. Finally, the edge boundary of the outer metal heat shield layer is folded over the edges of the insulation and inner metal layers to avoid any sharp edges, thus preventing injury to installers and reinforcing the heat shield structure to enhance useful life under vibration and heat conditions.
Patent CA-2405618-A1 (CA)
Title: Absorbent articles comprising a cationic polysaccharide and silicate
Inventor: DI CINTIO ACHILLE
IPC: A61F5/441
Filed: 2001-04-24
Abstract: The present invention relates to articles, preferably disposable absorbent articles like sanitary napkins and pantiliners, which comprise a cationic polysaccharide, preferably chitosan material, and silica. Such disposable absorbent articles deliver improved odor control performance (synergistic od or reduction) and improved fluid handling properties/absorption performance. In  one embodiment of the present invention, articles are provided which compris e crosslinked silica-cationic polysaccharides. These articles deliver not only  improved odor control and fluid handling properties when in use but are able  to maintain these properties even upon prolonged wearing time, typically upo n ageing of the bodily fluid in the articles and/or upon subsequent fluid discharge in the articles.
Patent CA-2405704-A1 (CA)
Title: Bombesin analogs for treatment of cancer
Inventor: BURMAN ANAND C
IPC: A61P35/00
Filed: 2000-07-31
Abstract: The present invention encompasses novel peptides that are antagonists to bombesin and bombesin like peptides and are useful in the treatment of cancer. The invention particularly relates to the design and synthesis of the novel peptides incorporating .alpha.,.alpha.-amino acids in a site specific manner. The invention encompasses methods for the generation of these peptides, compositions containing the peptides and the pharmacological applications of these peptides especially in the treatment and prevention of cancer.
Patent CA-2406487-A1 (CA)
Inventor: KIELLAND PETER JOHANN
IPC: B25H1/00
Filed: 2002-10-17
Abstract: A telescopic jack adapted to raise either wheel of a parked motorcycle by lifting and rotating a fixture located on the motorcycle's right side and over the pivot line formed between the tip of its kickstand and the ground contact point of one of its wheels. The telescopic jack assembly is comprised of a tube member engaged at its upper end to the motorcycle via a socketed engagement fixture. The tube member's lower end threadingly receives a coaxial jackscrew. The jackscrew's pointed lower end is engaged to the ground via a socketed foot member, said foot member also serving as a thrust bearing when the jackscrew is turned. A perpendicular hole through the jackscrew near its lower end permits the user to insert a rod and apply turning force. The user engages the socket of the upper engagement fixture under a bolt-head fixture or similar protrusion affixed to the motorcycle. When its jackscrew is turned, the jack assembly telescopes, thereby raising the motorcycle's nearest wheel off the ground. Means for blocking the motorcycle's wheels and adjusting its lean angle are also disclosed. Various upper engagement fixtures are also disclosed for adapting the jack to lift different vehicles.
Patent CA-2406597-A1 (CA)
Inventor: SMYTH JOHN ANDREW
IPC: C09D7/65
Filed: 2001-04-20
Abstract: The invention relates to a coating composition comprising (i) a supporting medium, and (ii) a plurality of cellulose particles, having an average dry particle size of less than 10 .mu.m, dispersed in the supporting medium, excluding aqueous coating compositions adapted for application to paper. The  invention also relates to a coating composition comprising (i) a supporting medium, and (ii) a plurality of cellulose particles, having an average dry particle size of less than 10 .mu.m, dispersed in the supporting medium in a n amount of less than about 5 g/L. The coating compositions of the invention form coatings which have useful thermal properties.
Patent CA-2410241-A1 (CA)
Title: Bird feeder with squirrel proof seed port
Inventor: OBENSHAIN JAMES ROBERTS
IPC: A01K39/01
Filed: 2002-10-30
Abstract: A squirrel proof bird feeder having a cylindrical reservoir for the containment of seeds and having at least one opening in the wall of the reservoir and one seed port for each opening, said seed port comprising: a platform having an opening congruent with the opening in the wall of the reservoir and a tunnel having a first opening defined by the opening in the platform and extending from the first opening through the opening in the reservoir, into the interior of the reservoir and terminating in a partially occluded second opening, effectively discriminates in favor of small birds, and especially against squirrels, by limiting access to seed within the reservoir.
Patent CA-2410516-A1 (CA)
Inventor: WU BIN
IPC: A61P43/00
Filed: 2001-05-30
Abstract: L'invention concerne des inhibiteurs de KIAA0175 réduisant l'expression ou les activités biologiques de KIAA0175, p53 et/ou p21 dans une cellule mammifère. Ces inhibiteurs de KIAA0175 consistent en des molécules antisens, des ribozymes, des anticorps et des fragments d'anticorps, des protéines et des polypeptides, ainsi qu'en de petites molécules. Ces inhibiteurs de KIAA0175 sont mis en application dans des compositions et des procédés servant à diminuer l'expression des gènes KIAA0175, p53 et/ou p21, et dans des procédés servant à augmenter la sensibilité à la chimiothérapie et/ou aux rayonnements de cellules mammifères, y compris des cellules tumorales, dans des procédés servant à diminuer les effets secondaires de la thérapie du cancer et dans des procédés servant à traiter des maladies néoplasiques.
Patent CA-2411046-A1 (CA)
Title: Massage device
Inventor: ROTH ROCHELLE B
IPC: A61H23/04
Filed: 2001-06-01
Abstract: A massage device for massaging a body part of a person in an unsupervised and unattended setting. The massage device includes a garment (200), shaped to provide a snug fit and having a plurality of bladders (250) arranged along the garment to massage the body part. An inflation assembly (300) supplies fluid pressure to each of the bladders to inflate the respective bladders. The bladders may have approximately the same inflated volume thereby equalizing the inflation volume of the respective bladders whereby substantially even inflation timing, with substantially even applied pressure, and, thus, overall smooth massage dynamics may be provided without overly complicated inflation fluid control. The garment may include a pocket (220) having an opening communication with the respective bladders and tubing (310) from the inflation assembly extends into this pocket. The inflation assembly may provide throttled deflation flow, tapered inflation/deflation patterns, and/or zone selector which allows a user to select a certain zone of the garment.
Patent CA-2412100-A1 (CA)
Title: Vibration-proof structure for metallic electrical packaging case
Inventor: HASEGAWA OSAMU
IPC: B60K1/04
Filed: 2002-11-19
Abstract: A vibration-proof structure i<or a metallic electrical packaging case includes a metallic electrical packaging case and a coupling member. The coupling member connects an outer wall of the metallic electrical packaging case and a member forming a side wall of a vehicle. Also, the coupling member may include an engaging portion at one end of the coupling member, which is used for temporarily fixing the coupling member, and an insertion engaging portion, which is engaged with a portion of the member forming the side wall of the vehicle, formed at another end of the coupling member.
Patent CA-2413957-A1 (CA)
Title: Vitronectin receptor antagonist pharmaceuticals for use in combination therapy
Inventor: CHEESMAN EDWARD H
IPC: A61K41/00
Filed: 2001-06-21
Abstract: The present invention describes novel kits and compositions comprising compounds of the formula (I):(Q)d-Ln-Ch, useful for the diagnosis and treatment of cancer in combination therapy in a patient. The present inventi on provides novel compounds useful for the treatment of rheumatoid arthritis. T he pharmaceuticals are comprised of a targeting moiety that binds to a receptor  that is upregulated during angiogenesis, an optional linking group, and a therapeutically effective radioisotope or diagnostically effective imageable  moiety.
Patent CA-2415901-A1 (CA)
Inventor: DULL GARY MAURICE
IPC: A61P25/28
Filed: 2001-07-11
Abstract: Selon l'invention, les patients sensibles ou souffrant d'états et de troubles, tels que des troubles du système nerveux central, sont traités par administration de compositions renfermant des sels d'acide 2, 3-diacyltartarique de composés nicotiniques, et en particulier des composés nicotiniques caractérisés sous forme d'amines à substitution aryle (des amines oléfiniques à substitution aryle, par exemple).
Patent CA-2415960-A1 (CA)
Inventor: BARK STEVEN J
IPC: C07K1/107
Filed: 2001-07-13
Abstract: The invention provides peptide synthons having protected functional groups f or attachment of desired moieties (e.g. functional molecules or probes). Also provided are peptide conjugates prepared from such synthons, and synthon and  conjugate preparation methods including procedures for identifying optimum probe attachment sites. Biosensors are provided having functional molecules that can locate and bind to specific biomolecules within living cells. Biosensors can detect chemical and physiological changes in those biomolecul es as living cells are moving, metabolizing and reacting to its environment. Methods are included for detecting GTP activation of a Pho GTP are protein using polypeptide biosensors. When the biosensor binds GTP-activated Rho GTPase protein, an environmentally sensitive dye emits a signal of a differe nt lifetime, intensity or wavelength than when not bound. New fluorophores whos e fluorescence responds to environmental changes are also provided that have improved detection and attachment properties, and that can be used in living  cells, or in vitro.
Patent CA-2416071-A1 (CA)
Title: Method of operating a talent business
Inventor: URREA RICHARD
IPC: G06Q10/06
Filed: 2003-01-13
Abstract: The invention is a method of selecting and recruiting extras for use in film and television production, comprising creating and maintaining a server with a database containing profiles for available extras. The casting director is then provided with a portable computer to connect to and access the database. The casting director downloads selected portions of the database to the portable computer and selects the required extras from the profiles in the selected portion of said database.