baber/WOPTO huggingface dataset:
Patent AU-2019229606-A1 (AU)
Title: Improvements in variant detection
Inventor: FISHER EYAL
IPC: C12Q1/6869
Filed: 2019-03-06
Abstract: The present invention provides a computer-implemented method for detecting cell-free DNA (cfDNA), such as circulating tumour DNA, in a DNA-containing sample obtained from a patient, the method comprising: (a) providing loci of interest comprising at least 2 mutation-containing loci representative of a tumour of the patient ("patient-specific loci"); (b) providing sequence data comprising sequence reads of a plurality of polynucleotide fragments from a DNA-containing sample from the patient, wherein said sequence reads span said at least 2 mutation-containing loci of step (a); (c) optionally, performing reads collapsing to group the sequence reads into read families; (d) calculating the mutant allele fraction across some or all of said at least 2 patient-specific loci, optionally wherein the mutant allele fraction is calculated by aggregating mutant reads and total reads; (e) classifying the sample as containing or not containing the target cfDNA based on the calculated mutant allele fraction. Also provided a related methods and systems.
Patent AU-2019236617-A1 (AU)
Title: Anti-c5 antibodies having improved pharmacokinetics
Inventor: ANDRIEN JR BRUCE A
IPC: C07K16/40
Filed: 2019-09-24
Abstract: Abstract The disclosure provides antibodies that are useful for, among other things, inhibiting terminal complement (e.g., the assembly and/or activity of the C5b-9 TCC) and C5a anaphylatoxin-mediated inflammation and, thus, treating complement-associated disorders. The antibodies have a number of improved properties relative to eculizumab, including, e.g., increased serum half-life in a human.
Patent AU-2019236711-A1 (AU)
Title: Cushion Set
Inventor: LEVERETT DAVID
IPC: A47C27/14
Filed: 2019-09-26
Abstract: Provided is a cushion set including a pad (10), a filling pad (20), an envelope (30), 
and a support pad set (40). The pad (10) has a first-tier sunken portion (14) and a 
second-tier sunken portion (15). The filling pad (20) is disposed in the second-tier sunken 
5 portion (15). The envelope (30) is disposed on the pad (10). The envelope (30) has a 
pocket-shaped body (31). A plurality of coupling portions (32) is disposed at edges of the 
body (31). The support pad set (40) includes an upper foam pad (41), a lower foam pad 
(42), and a soft gel pad (43). The support pad set (40) is disposed in the body (31) of the 
envelope (30). The soft gel pad (43) corresponds in position to the filling pad (20) of the 
10 second-tier sunken portion (15) of the pad (10).  
9
30 
32 
10 
FIG.1 
12 
33 
32
\6 
33 1 
FIG. 2
Patent AU-2019267080-A1 (AU)
Title: Bi-dose nasal spray
Inventor: FRÖHLICH JOHANNES MALTA
IPC: G09B23/28
Filed: 2019-05-08
Abstract: The present invention relates to a novel nasal spray containing an aqueous solution or a fluid with an anxiolytic or anticonvulsant substance, wherein the nasal spray is characterized in that with the nasal spray, two sprays with each an equivalent, defined volume of the aqueous solution or liquid of the active agent, can be intranasally administered to a patient and wherein the nasal spray allows for an administration, independent of the spatial orientation of the nasal spray in any position of the patient (standing upright, sitting, lying or in any intermediate position). The nasal spray can be used directly without prior activation. Preferably it is apparent from the nasal spray whether a spray or even a second spray has been made with the nasal spray. Preferably, a spray of the nasal spray can be administered one- handed by the patient or a third person. The active agent in the inventive nasal spray is a benzodiazepine or a GABA-receptor agonist, preferably midazolam or a derivative thereof or a salt of these active agents. The nasal spray according to the present invention may be used for sedation, premedication or treatment of patients with claustrophobia, anxiety disorders or panic attacks or for the treatment of convulsions in CNS diseases, particularly in epileptic seizures or other manifestations of seizures (e.g. febrile convulsions). The invention also relates to a method for hermetically sealing an active agent container for use in supplying an nasal spray in accordance with the invention. The invention also relates to a method of detection by localizing the locally precise administration of an active agent in nasal application, as well as a nasal spray, preferably a bi-dose nasal spray, for which, using the cited method of detection, it has been shown both visually (qualitatively) and quantitatively that an orientation-independent, uniform and locally precise administration of the dose of the active agent onto the nasal mucosa of a patient can be achieved. Also provided is a method for airless and air-tight sealing of an active agent container in accordance with the invention.
Patent AU-2019299299-A1 (AU)
Title: Method for lowering iodine value of glyceride
Inventor: LI XIANGYU
IPC: C11C3/10
Filed: 2019-07-04
Abstract: A method for lowering the iodine value of glyceride, comprising: enabling glyceride, saturated fatty acid and alkali to perform catalytic reaction under the action of lipase so as to obtain glyceride having a low iodine value. By means of sufficient quantity of saturated fatty acid residues provided by a saturated fatty acid salt formed in-situ by corresponding saturated fatty acid and alkali and the catalytic action of one-directional lipase, the reaction conditions are mild; the side reaction is rare; and the iodine value of glyceride is effectively lowered.
Patent AU-2019316635-A1 (AU)
Title: Imidazotetrazine compounds
Inventor: HERGENROTHER PAUL J
IPC: C07D235/02
Filed: 2019-08-09
Abstract: New synthetic methods to provide access to previously unexplored functionality at the C8 position of imidazotetrazines. Through synthesis and evaluation of a suite of compounds with a range of aqueous stabilities (from 0.5 to 40 hours), a predictive model for imidazotetrazine hydrolytic stability based on the Hammett constant of the C8 substituent was derived. Promising compounds were identified that possess activity against a panel of GBM cell lines, appropriate hydrolytic and metabolic stability, and brain-to-serum ratios dramatically elevated relative to TMZ, leading to lower hematological toxicity profiles and superior activity to TMZ in a mouse model of GBM.
Patent AU-2019351809-A1 (AU)
Title: Biodegradable lipids for the delivery of active agents
Inventor: JAYARAMAN MUTHUSAMY
IPC: C12N15/88
Filed: 2019-09-27
Abstract: The present invention relates to a cationic lipid having one or more biodegradable groups located in a lipidic moiety (
Patent AU-2019362658-A1 (AU)
Title: Conjugates of hyaluronic acid and aminobisphosphonates and the therapeutic use thereof
Inventor: PLUDA STEFANO
IPC: C08L5/08
Filed: 2019-10-11
Abstract: The present invention describes conjugates of hyaluronic acid (HA) and an amino-bisphosphonate (N-BP) of general formula (I): Formula (I) wherein L, m, n and x are as defined in claim 1, and the salts thereof. Said conjugates and the pharmaceutical compositions thereof are useful in the intra-articular and/or locoregional treatment of osteoarthrosis and its repercussions at cartilage and subchondral level; in the treatment of post-menopausal or drug-induced osteoporosis; in the treatment of bone fragility due to trauma or disease; and in the intraosseous and/or locoregional treatment of disorders characterised by altered metabolic bone turnover, in particular Paget's disease. They are also useful to improve the osseointegration of prostheses.
Patent AU-2019364197-A1 (AU)
Title: Toner cartridge electrical contacts
Inventor: AMANN MARK WILLIAM
IPC: G03G15/00
Filed: 2019-10-01
Abstract: A toner cartridge according to one example embodiment includes a housing having a reservoir for holding toner. A first electrical contact and a second electrical contact are positioned on a first longitudinal end of the housing. The first electrical contact is electrically connected to processing circuitry positioned on the housing. The second electrical contact is electrically connected to an imaging component positioned on the housing. The first electrical contact is positioned higher than the second electrical contact. A first drive coupler and a second drive coupler are positioned on a second longitudinal end of the housing. The first electrical contact and the second electrical contact are positioned higher than a first rotational axis of the first drive coupler. The first electrical contact is positioned higher than a second rotational axis of the second drive coupler and the second electrical contact is positioned lower than the second rotational axis.
Patent AU-2019390401-A1 (AU)
Title: Methods to improve beverage quality
Inventor: BROCIA ROBERT
IPC: A61P25/24
Filed: 2019-11-26
Abstract: Agave derived beverages with improved quality contain enhanced ratios of MAO B to MAO A inhibitors or enhanced concentration of inhibitor of MAO B.
Patent AU-2019403411-A1 (AU)
Title: Integral magnet mount for golf ranging devices
Inventor: NYHART SCOTT O
IPC: A63B57/00
Filed: 2019-12-20
Abstract: A golf laser rangefinder comprises a housing with a pair of opposing side wall portions. One of the side wall portions has a magnetic attraction strip extending diagonally across the side wall portion for attachment to, for example, an upright roof support member of a golf cart. A display on the side wall portion opposite the magnetic attraction strip can provide data display, including real time data, to the driver or passenger of the golf cart when the laser rangefinder is mounted to the support member.
Patent AU-2019427999-A1 (AU)
Title: Multistage pump body and multistage gas pump
Inventor: ILTCHEV THEODORE
IPC: F01C21/10
Filed: 2019-02-06
Abstract: A multistage pump body comprises a first pumping chamber (20) and a second pumping chamber (21). A connecting duct (26a) puts an outlet (27) of the first pumping chamber (20) into communication with an inlet (28) of the second pumping chamber (21). A leaktight conduit (40) is provided for the circulation of a cooling liquid. The connecting duct (26a) is a lateral duct of the multistage pump body. A heat-conducting wall (33) partially delimits the connecting duct (26a) and has an external surface (34) on the outside. At least one portion of the connecting duct (26a) passes between this external surface (34) of the heat-conducting wall (33) and the leaktight conduit (40).
Patent AU-2019431304-A1 (AU)
Title: Method and apparatus for producing ternary cathode material
Inventor: FENG EDWARD
IPC: F27B9/06
Filed: 2019-02-26
Abstract: A method for producing a ternary cathode material (130) for lithium batteries by roasting raw material (110) in a roasting kiln (120), wherein an atmosphere is provided in the roasting kiln (120), wherein injection of a gas component (a) of the atmosphere into the roasting kiln (120) is controlled in closed loop control manner, based on at least one process influencing parameter being measured, as well as an apparatus for producing a ternary cathode material (130).
Patent AU-2019432617-A1 (AU)
Title: Coffee beverage packed in container
Inventor: MATSUBAYASHI HIDEKI
IPC: A23F5/24
Filed: 2019-12-02
Abstract: The purpose of the present invention is to provide a coffee beverage packed in a container in which a reduction in flavor is suppressed.　This coffee beverage has a coffee solids content of 0.3 to 3.0% by mass, and contains 0.1 to 2.0 mg/100 mL of 1-deoxynojirimycin.
Patent AU-2019441241-A1 (AU)
Title: Anti-hypertensive and cholesterol-lowering fixed-dose combination and method of manufacture
Inventor: STIMITS ROY A
IPC: A61K45/06
Filed: 2019-04-17
Abstract: Disclosed is a method of manufacturing a cardiovascular fixed-dose combination pharmaceutical dosage form that includes an anti-hypertensive active agent, a cholesterol-lowering active agent, and optionally, an enteric-coated aspirin or platelet inhibitor. The fixed-dose combination is prepared with at least two granulation solutions that are free of citric acid and enhance the aqueous solubility of the cholesterol-lowering agent in fixed-dose combination. The active agents in the resulting dosage form, which is also free of citric acid, have the same strength and release profiles as the same active agents prepared as a single formulation.
Patent WO-2021179030-A1 (WO)
Inventor: NORRIS CHARLES
IPC: H01J49/42
Filed: 2020-03-10
Abstract: The invention relates to a system for aligning the firing of a laser-ablation apparatus to a signal or property of an inductively-coupled-plasma mass-spectrometer apparatus. At least one kind of input unit that receives timing data from the mass-spectrometer and isolates the system. A processor configured to translate the mass cycle of the mass-spectrometer into a series of triggering signals to fire the laser. A delay circuit to retard the triggering signals by a specified duration. At least one kind of signal output unit to deliver a triggering signal to the laser. A method for configuring a system for controlling a laser in laser-ablation inductively-coupled-plasma mass-spectrometry as above. A computer program product for controlling a laser in laser-ablation inductively-coupled-plasma mass-spectrometry as above.
Patent AU-2020202652-A1 (AU)
Title: Compositions, kits, and methods to induce acquired cytoresistance using stress protein inducers
Inventor: ZAGER RICHARD
IPC: A01N1/02
Filed: 2020-04-20
Abstract: The present disclosure provides compositions, kits, and methods to protect organs by inducing acquired cytoresistance without causing injury to the organ. The compositions, kits, and methods utilize heme proteins, iron and/or vitamin B12 and, optionally, agents that impact heme protein metabolism.
Patent AU-2020222078-A1 (AU)
Title: Cas12a guide RNA molecules and uses thereof
Inventor: PETRIS GIANLUCA
IPC: C12N15/113
Filed: 2020-02-11
Abstract: Engineered Cas12a guide RNA (gRNA) molecules useful, for example, for correcting aberrant RNA splicing resulting from mutations in a genomic DNA sequence and for preventing exon inclusion in mature mRNA.
Patent AU-2020226219-A1 (AU)
Title: Financial instrument composition visualization tool
Inventor: EVANGELIOU JOHN
IPC: G06Q40/06
Filed: 2020-02-21
Abstract: Systems and methods for visualizing investments are provided. An investment visualization tool includes a group of a plurality of entries associated with a first asset class. The group includes at least two subgroups associated with respective market characteristics. The group also includes a plurality of entries, each displaying a respective identifier and/or a respective numerical value. The entries are each disposed in one of the at least two subgroups, share a common visual characteristic associated with each subgroup, and are disposed substantially contiguously within the subgroups.
Patent AU-2020230845-A1 (AU)
Title: Power supply circuit for a cooking device and cooking device
Inventor: ZANGOLI MASSIMO
IPC: H05B6/06
Filed: 2020-02-20
Abstract: The invention relates to a power supply circuit (1, 2) for a cooking device, in particular for an induction cooking device, more particularly for an induction hob (80), wherein the power supply circuit is comprising - a, in particular a single, frequency adapting unit (20), in particular filtering unit, for adapting at least one external supply signal (11, 12) into a single or at least one internal AC supply signal (15, 16; 17, 18), - and at least one, at least two, two, at least three or three DC signal generating units (25, 30, 35), each for converting the one or at least one internal AC supply signal (15, 16; 17, 18) into at least one signal component, in particular one or two signal components, of an internal DC supply signal (40, 41, 42, 43, 44; 45, 46) and - at least one, at least two, in particular two, at least three, three, at least four or four, heating frequency generating units (50, 55), each for converting one or at least one DC supply signal (40, 41; 42, 43; 44, 46; 45, 46) supplied by at least one DC signal generating unit (25, 30, 35) into a heating frequency signal (61, 62, 63, 64) for supplying at least one heating unit (70, 75) with electrical power.
Patent AU-2020247835-A1 (AU)
Title: Computer systems and methods including HTML browser authorisation approaches
Inventor: SPEAK GRAEME
IPC: G06F21/31
Filed: 2020-03-30
Abstract: In one form of the present invention, there is provided a computer implemented method 10 of enabling one or more access provider systems 12 to secure access to content on first electronic devices 14, the computer implemented method 10 comprising: receiving encrypted input information 16, the encrypted input information 16 being inputted by users 18 on second electronic devices 20; and transmitting input information 16 to the one or more access provider systems 12 to allow the one or more access provider systems 12 to determine whether to authorise access to content on the first electronic devices 14.
Patent AU-2020249603-A1 (AU)
Title: Multicomponent thermoplastic product
Inventor: GUILLAMOT FRÉDÉRIQUE
IPC: D01F8/04
Filed: 2020-03-27
Abstract: The present invention relates to a multicomponent plastic product comprising at least two different thermoplastic materials, wherein a first thermoplastic material comprises a first thermoplastic polymer, and a second thermoplastic material comprises at least a second thermoplastic polymer and at least one degrading enzyme able to degrade the first thermoplastic polymer. The second thermoplastic material has a transformation temperature (Tf) lower than the transformation temperature (Tf) of the first thermoplastic material, and the first and second plastic materials are at least partially adjacent in the multicomponent product.
Patent AU-2020259271-A1 (AU)
Title: Semisolid multi-phase oral composition comprising hydrophilic bleaching agent particles
Inventor: SAGEL PAUL ALBERT
IPC: A61K8/22
Filed: 2020-04-08
Abstract: A semisolid multi-phase oral composition in form of a dispersion for whitening teeth.
Patent AU-2020279887-A1 (AU)
Title: Age verification with registered cartridges for an aerosol delivery device
Inventor: DAUGHERTY SEAN
IPC: A24F40/50
Filed: 2020-05-15
Abstract: An electronic nicotine delivery systems ("ENDS") device may include aerosol delivery devices such as smoking articles that produce aerosol. The device may include a cartridge for the aerosol production. The cartridge is assigned a unique identifier that is approved for a user or that user's device such that the cartridge and/or the device only operate when approved. The unique identifiers help with user identification, tracking, and age verification.
Patent AU-2020281064-A1 (AU)
Title: Bicyclic compounds
Inventor: NARINE ARUN
IPC: C07D487/04
Filed: 2020-12-02
Abstract: Bicyclic compounds 
Abstract 
The present invention relates to compounds of formula I, 
5 
2 
R 
R N 
PONQ> -Ar 
(I) 
wherein the variables are defined as given in the description and claims. The invention further 
0 relates to uses, processes and composition for compounds I.  
16902155_1 (GHMatters)P44390AU01
Patent AU-2020284722-A1 (AU)
Title: MCT-based nutrition blend for providing health benefits in animals
Inventor: IZQUIERDO OSCAR
IPC: A61P3/04
Filed: 2020-05-29
Abstract: A method for weight loss comprising orally administering a composition comprising a therapeutically effective amount of medium chain triglycerides to the animal, where the medium chain triglycerides include caprylic acid.
Patent AU-2020294302-A1 (AU)
Title: Transmitting apparatus and receiving apparatus and controlling method thereof
Inventor: BAE JAE-HYEON
IPC: H04L27/26
Filed: 2020-12-24
Abstract: A transmitting apparatus is provided. The transmitting apparatus includes: a frame generator 
configured to generate a frame including a plurality of orthogonal frequency-division multiplexing 
(OFDM) symbols; and a guard interval (GI) inserter configured to insert GIs into the generated frame, 
wherein the plurality of OFDM symbols are divided into a bootstrap, a preamble, and a payload, and 
the GI inserter inserts first GIs having a size corresponding to a fast Fourier transform (FFT) size of 
each of OFDM symbols configuring the payload into front ends of each of the OFDM symbols, 
inserts second GIs having a size corresponding to a f4 quotient obtained by dividing an extra region of 
the payload calculated based on the FFT size of the OFDM symbols configuring the payload, the 
number of OFDM symbols, and the size of the first GIs by the number of OFDM symbols into front 
ends of each of the first GIs, and inserts a cyclic postfix (CP) having a size corresponding to the 
remainder remaining after dividing the extra region of the payload by the number of OFDM symbols 
into a rear end of a final OFDM symbol configuring the payload.
Patent AU-2020331416-A1 (AU)
Title: Privacy panel and system
Inventor: ERDMAN DEREK
IPC: E04B2/74
Filed: 2020-08-10
Abstract: An engineered privacy panel comprising a recycled rubber composition, where the panel comprises one or more integral reinforcement members for reinforcement and providing fastening means for fastening the back of the panel to a support. The privacy panel can be used to make partitions and partition systems, each of which can be provided as a kit.
Patent AU-2020337159-A1 (AU)
Title: Screening method, device, and kit for detecting mucosal carbohydrates and associated conditions
Inventor: SHAMSUDDIN ABULKALAM MOHAMMED
IPC: G01N33/53
Filed: 2020-07-24
Abstract: This disclosure relates to a screening test method, device, and kit for mucosal carbohydrates and associated conditions including, cancerous and precancerous conditions. Specifically, the method tests abnormal carbohydrates in mucus or body fluid using reagents of galactose oxidase, and Schiffs Reagent. The screening test method, device, and kit provides improved accuracy, and minimizes handling procedures. This disclosure further relates to the use of the device or kit in a healthcare facility for an initial evaluation for cancerous and precancerous conditions.
Patent AU-2020350514-A1 (AU)
Title: Syringe control assembly
Inventor: ODA TODD
IPC: A61M5/168
Filed: 2020-09-14
Abstract: Syringe control assemblies are described herein. A syringe control assembly includes an assembly body, a first syringe, a second syringe, and a pump assembly. The first and second syringes are releasably coupled to a syringe mounting rack of the assembly body. The pump assembly includes a first pump unit and a second pump unit. Each pump unit is in fluid communication with each respective syringe. In a priming configuration, the first pump unit is configured to draw fluid flow from the first syringe cavity and the second pump unit is configured to pump fluid flow into the second syringe cavity.
Patent AU-2020351274-A1 (AU)
Title: Single-domain antibodies directed against LILRB2
Inventor: LOUSTAU MARIA
IPC: C07K16/28
Filed: 2020-09-18
Abstract: The present invention relates to single-domain antibodies (sdAbs) directed against Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2), pharmaceutical compositions comprising
Patent AU-2020372873-A1 (AU)
Title: Rapidly insertable central catheter and methods thereof
Inventor: HOWELL GLADE HAROLD
IPC: A61M5/00
Filed: 2020-10-26
Abstract: Rapidly insertable central catheters ("RICC") and methods thereof are disclosed. For example, a RICC can include a catheter tube, a suture wing disposed over a medial portion of the catheter tube, a hub coupled to a proximal-end portion of the catheter tube, and a number of extension legs extending from the hub. The catheter tube can include a first section in a distal portion of the catheter tube and a second section proximal of the first section. The second section of the catheter tube can include an outer layer extruded over an inner layer such that an outer diameter of the catheter tube is larger in the second section than the first section of the catheter tube. The catheter tube can have a column strength sufficient to prevent buckling when the catheter tube is inserted into an insertion site and advanced through vasculature of a patient.