baber/WOPTO huggingface dataset:
Patent CA-2523743-A1 (CA)
Title: Heterocycle substituted carboxylic acids as inhibitors of protein tyrosine phosphatase-1b
Inventor: HU SHAOJING
IPC: C07D409/10
Filed: 2004-04-30
Abstract: The present invention relates to compounds and pharmaceutically acceptable salts of formula (I), which are useful in the treatment of metabolic disorders related to insulin resistance, leptin resistance, or hyperglycemia. Compounds of the invention include inhibitors of Protein tyrosine phosphatases, in particular Protein tyrosine phosphatase-1B (PTP-1B), that are useful in the treatment of diabetes and other PTP mediated diseases, such as cancer, neurodegenerative diseases and the like. Also disclosed are pharmaceutical compositions comprising compounds of the invention and methods of treating the aforementioned conditions using such compounds.
Patent CA-2527067-A1 (CA)
Title: Digital can decorating apparatus
Inventor: FINAN JOSEPH
IPC: B41F17/00
Filed: 2004-04-21
Abstract: A digitally controlled can printing apparatus for printing on circular two-piece cans, the apparatus including digital print-heads (30) for printing an image on the cans and drives (29) for transporting and rotating the cans in front of the print-heads (30) in registered alignment.
Patent CA-2528774-A1 (CA)
Title: Small molecule toll-like receptor (tlr) antagonists
Inventor: ZEPP CHARLES M
IPC: C07D401/10
Filed: 2004-06-18
Abstract: The invention provides methods and compositions useful for modulating signaling through Toll-like receptors. The methods involve contacting a TLR-expressing cell with a small molecule having a core structure including at least two rings. Certain of the compounds are 4-primary amino quinolines. Many of the compounds and methods are useful specifically for inhibiting immune stimulation involving at least one of TLR9, TLR8, TLR7, and TLR3. The methods may have use in the treatment of autoimmunity, inflammation, allergy, asthma, graft rejection, graft versus host disease, infection, sepsis, cancer, and immunodeficiency.
Patent CA-2529121-A1 (CA)
Inventor: LIN CHUN H
IPC: B42F13/26
Filed: 2005-12-05
Abstract: A ring mechanism for retaining loose-leaf pages comprises a housing and ring members for holding loose-leaf pages that are moveable relative to the housing between an open and closed position. An actuation system moves the ring members and includes hinge plates pivotally mounted on the housing and a lever actuating pivoting movement of the hinge plates in at least one direction (e. g., moving the hinge plates and ring members to the open position). The lever is connected to a travel bar that moves lengthwise of the housing between a position blocking pivoting movement of the hinge plates and a position allowing pivoting movement of the hinge plates. At least one of the lever and the hinge plates deforms when the lever moves to delay pivoting movement of the hinge plates so that the lever may move the travel bar so that it does not block movement of the hinge plates.
Patent CA-2529975-A1 (CA)
Title: Livestock flooring cover
Inventor: KOELKER TODD J
IPC: A01K1/015
Filed: 2005-12-13
Abstract: A slat cover for livestock flooring, particularly hog flooring, includes a base to overlie an individual slat of a floor of parallel individual slats, or a slat of a gang slat panel. Legs are joined to the base at the opposing sides of the base and terminate in an outwardly flared free edge. The legs are receivable in slots between individual slats or slots provided in a gang slat panel, the legs conforming to the corners of the slat and gripping the upper part of the opposing sidewalls of the slat. Traction bars or knobs or elastomeric strips are fixed to the upper surface of the base. A combination slat and alternate slat cover is also disclosed, the slat including a leg engaging region on each of its sidewalls. The alternate slat cover has a base with opposing downwardly extending legs which are integrally formed at a perpendicular to the base.  Each leg includes a ridge to be received in a corresponding groove on the leg engaging region of the sidewall.
Patent CA-2532863-A1 (CA)
Inventor: HUSZCZO RANDAL
IPC: F16B2/06
Filed: 2006-01-13
Abstract: A clamping cartridge for releasably clamping a plurality of panel-type articles in generally parallel spaced-apart manner comprising: a frame; clamping means spaced-apart along the frame, said clamping means being generally oriented perpendicular to their direction of spacing and being normally biased towards a closed position; actuation means operable in association with said clamping means for opening and closing said clamping means in unison; and a slide associated with each of said clamping means.
Patent CA-2533189-A1 (CA)
Title: Single clutch transmission
Inventor: TAPPER STEVE
IPC: F16H3/091
Filed: 2004-07-21
Abstract: A two speed transmission includes an input shaft; a lay shaft spaced from the input shaft; a first gear train connecting the input shaft to the lay shaft; a second gear train connecting the lay shaft to an output shaft the gear train including a one way clutch or similar; and a clutch for engaging the input shaft with the output shaft. The transmission is arranged such that when the output shaft is disengaged from the input shaft power is transmitted to the output shaft via the first and second gear trains and the lay shaft. When the clutch is disengaged, power is transmitted from the input shaft via the gear trains and the lay shaft via the one way clutch to the output shaft which typically provides first or low gear for use in low speed manoeuvring or where greater torque is required. With the clutch engaged, power may be transmitted from the input shaft directly to the output shaft to provide a second gear for when the watercraft is cruising. This transmission system has the advantage of being extremely compact and since, it requires only a single clutch, provides reduced drag compared with transmission systems incorporating more than one clutch. Advantageously, the default for the transmission has the one way clutch or similar in the first or lower gear, with the clutch normally on, so that if the system fails, it is always possible for the boat owner to get the boat home albeit at a slower speed.
Patent CA-2533699-A1 (CA)
Title: Anterior cervical plating system with multi-lock having a non-circular perimeter
Inventor: MICHELSON GARY KARLIN
IPC: A61B17/70
Filed: 1998-02-11
Abstract: Anatomically contoured anterior cervical plates with bone ingrowth surfaces, providing for intersegmental compressive preloading, and a rigid and locked interface to all of the bone screws, with those engaging the vertebrae deployed in highly convergent pairs. The bone screws have a tapered self-tapping leading end, an increasing root diameter with a generally constant outer diameter with a thread that is narrow and sharp throughout and an enlarged head portion capable of an interference fit to the receiving holes of the plate. Instrumentation consists of plate holders, a compression apparatus and a pilot hole forming device that interlocks with the plate. Methods for spinal compression and bone hole preparation are provided.
Patent CA-2533979-A1 (CA)
Title: Medical instrument including an end effector having a medical-treatment electrode
Inventor: CROPPER MICHAEL S
IPC: A61B17/94
Filed: 2006-01-25
Abstract: A medical instrument includes a flexible sheath and an end effector. The sheath has a distal end. The end effector is attached to the sheath proximate the distal end and is insertable into a patient. The end effector includes opposing and retroflexed first and second jaws and includes at least one medical-treatment electrode supported by the second jaw. At least one of the first and second jaws is rotatable. In one implementation, the at-least-one medical-treatment electrode is operatively connectable to a medical radio-frequency (RF) generator. In one application, the end effector is insertable into the esophagus of a patient. In one employment, the first and second jaws are adapted to grasp a working end of a flexible tube of an endoscope.
Patent CA-2535976-A1 (CA)
Inventor: WANG QIANG
IPC: A61K39/395
Filed: 2004-08-20
Abstract: This invention provides isolated nucleic acid and amino acid sequences encoding VG5Q, a novel angiogenic growth factor protein with pro-angiogenic activity, a forkhead-associated domain, a G-patch domain; characteristic subcellular localization in an in vitro Matrigel model of angiogenesis:  towards the cell periphery in early stages of tubulogenesis, between cells in newly formed endothelial tubes, and no nuclear staining after 24 hours; is expressed in endothelial cells; is secreted during angiogenesis; and interacts with TWEAK. The invention also provides for expression vectors containing nucleic acid sequences encoding VG5Q protein, and host cells containing one or more expression vectors for the recombinant expression of VG5Q. The invention also provides for methods of using VG5Q for the diagnosis and treatment of angiogenesis-mediated diseases or disorders.
Patent CA-2541807-A1 (CA)
Title: Stent graft retention system
Inventor: OELENSCHLAEGER BENT
IPC: A61F2/966
Filed: 2004-10-12
Abstract: A retention system for retaining a stent graft (13) onto a deployment device (1) in which the stent graft has an exposed stent (11) at at least one end.  The deployment device has a capsule (7) to receive the exposed stent during deployment and an arrangement to move the capsule to release the exposed stent when required. A release wire (17) associated with the deployment device engages a portion (19) of the exposed stent within the capsule to retain the exposed stent in the capsule. At least one retention loop (25) on the stent graft is connected around the release wire to prevent removal of the capsule from the exposed stent until the release wire has been removed from its engagement with the exposed stent within the capsule and the retention loop is released.
Patent CA-2543633-A1 (CA)
Title: System and method for delivery point packaging
Inventor: MILEAF DARYL SUNNY
IPC: G06F17/00
Filed: 2004-10-22
Abstract: The mail sorting systems and methods of the invention can be used to provide a mail carrier with a batch of mail that is arranged in delivery point order and separated by delivery point. Advantageously, the systems and methods employ an expandable, transportable container having a number of expandable compartments. Each expandable compartment holds the mail for a single delivery point.
Patent CA-2544487-A1 (CA)
Inventor: RAVISHANKAR HEMA
IPC: A61K9/20
Filed: 2004-09-15
Abstract: The invention relates to a multilayer dosage form for the controlled release of active substances, which substantially comprises a) optionally a neutral core (nonpareilles), b) an inner control layer, comprising a modulatory effective substance that is embedded in a matrix that influences release of a modulatory substance, said matrix comprising pharmaceutically acceptable polymers, waxes, resins and/or proteins and optionally an active substance, c) an active substance layer, comprising a pharmaceutically active substance and optionally a modulatory effective substance, d) an outer control layer, comprising at least 60 % by weight of one or more mixtures from a plurality of (meth)acrylate copolymers, 98 to 85 C1 to C4 alkyl esters of the (meth)acrylic acid and 2 to 15 % by weight of methacrylate monomers with a quaternary ammonium group in the alkyl group, and optionally up to 40 % by weight of additional pharmaceutically acceptable polymers. The dosage form is further characterized in that the layers additionally contain, in a manner known per se, pharmaceutically common adjuvants.
Patent CA-2549127-A1 (CA)
Title: Methods and compositions for inhibiting metal corrosion
Inventor: FROST KEITH A
IPC: C23F11/04
Filed: 2004-11-19
Abstract: Methods and compositions are provided that inhibit the corrosion of metal surfaces by aqueous acid solutions. The inhibition is basically achieved by the addition of a reaction product of an alpha,beta-unsaturated aldehyde, or ketone with a primary or secondary amine to the aqueous acid solution.
Patent CA-2550548-A1 (CA)
Inventor: TIMPERMAN EUGENE L
IPC: A61B17/068
Filed: 2006-06-20
Abstract: A surgical stapling and severing instrument particularly suited to endoscopic use includes a proximal portion that is manipulated external to a patient to position an attached elongate shaft and end effector to a desired surgical site inside of the patient. An articulation joint pivotally attaches the end effector to the elongate shaft to give further clinical flexibility in reaching tissue at a desired angle. A closure tube assembly includes a multiple pivoting portion that overrides the articulation joint in order distally translate to close the end effector yet pass over an articulated shaft. Thereby, additional clinical flexibility in positioning the end effector is achieved without losing the ability for separate closure and firing motions transferred by the shaft. Thereby, design flexibility is achieved by avoiding the design constraints of transferring a mechanical motion through the tight confines of the elongate shaft sufficient to effect articulation.
Patent CA-2550801-A1 (CA)
Inventor: YAO JING JAMES
IPC: E21B10/38
Filed: 2006-06-22
Abstract: A percussion rock drill comprising a drill string having in combination a drill rod, a drilling bit threaded on the end of said drill rod, and at least one ridged reinforcing drill string guiding sleeve sleeved on and bonded to the drill rod with the first sleeve located immediately next to the drilling bit. The sleeve has an outer cylindrical surface having a diameter substantially the same as but not larger than the diameter of a hole that the bit would cut under operation of the rock drill.     The sleeve preferably has cuttings guiding passageways in its periphery which preferably are helically fluted.
Patent CA-2552635-A1 (CA)
Inventor: YU YI DING
IPC: B41J2/175
Filed: 2005-01-18
Abstract: L'invention concerne une cartouche d'encre pour imprimante à jeu d'encre, qui se caractérise en ce qu'elle comporte un système d'alimentation en encre comprenant une fibre longue et mince (4) autour de l'orifice de sortie de l'encre (6), un levier (1) à base d'une partie ou d'un matériau élastique, qui s'étend de haut en bas et un tube capillaire (3) s'étendant en labyrinthe. Cette nouvelle cartouche d'encre assure une alimentation régulière et fiable en encre et par conséquent une exécution homogène du processus d'impression. La pression régnant à l'intérieur du réservoir d'encre de la cartouche d'encre est maintenue dans une plage étroite, limitée, ce qui permet d'augmenter la portée et le rendement de l'impression, de réduire la consommation et avant tout les déperditions d'encre. Les coûts de production de la cartouche d'encre sont réduits et cette cartouche d'encre est bien adaptée à la production de masse, tout en garantissant une qualité élevée.
Patent CA-2553678-A1 (CA)
Title: Multi-user adaptive array receiver and method
Inventor: ROY SEBASTIEN JOSEPH ARMAND
IPC: H04B1/16
Filed: 2005-01-31
Abstract: An array receiver which reduces complexity and cost by exploiting multiuser information in signals received from a plurality of transmitting users preprocesses (40) samples of antenna signals ( x1, x2..., xN) from the antenna elements (22/1,..., 22/N) to form basis signals (yO,..., yM) together having fewer space-time dimensions than the space-time dimensions of the combined antenna signals. The receiver processes and combines the basis signals to produce sets of estimated received signals (z0,..., zM), each for a corresponding one of the users. Each of the basis signals comprises a different combination of the antenna signals. The receiver combines the basis signals to provide a user-specific output signal, and periodically updates parameters of the filters (40/0,..., 40/M) used for deriving each particular basis signal such that each user-specific output signal will exhibit a desired optimized concentration of energy of that user's received signal as received by the array antenna.
Patent CA-2556277-A1 (CA)
Title: Method and device for generating retinal images using the stigmatism of the two foci of a substantially elliptical sight
Inventor: HAMDANI RACHID
IPC: G02B17/06
Filed: 2005-02-09
Abstract: The method involves positioning an object near a focus (F) of an elliptical refracting surface (E), and positioning an image near a focus (F`) of the surface. The object constitutes of a diaphragm of a pinhole that forms point of convergence of an image, which is generated by a light display or a collimated light source. The image is reflected by semi-reflecting surface of the surface (E) and projected near retina of eye of an observer. An independent claim is also included for a device for the implementation of the retinal image creating method.
Patent CA-2557514-A1 (CA)
Title: Method and apparatus for measuring properties of concrete
Inventor: YU XIONG
IPC: G01N22/00
Filed: 2005-02-28
Abstract: Methods and apparatus using time domain reflectometry to determine electrical properties of concrete for calculating physical and mechanical properties of the concrete that are indicative of concrete quality and durability. The dielectric constant of a concrete is determined to calculate the gravimetric water content of the concrete for use in finding the water-cement ration of the concrete. Electrical conductivity of curing concrete is determined to calculate compressive strength of the concrete for use in predicting strength development in the concrete.
Patent CA-2559374-A1 (CA)
Inventor: MOLINO MICHELE
IPC: C07D207/28
Filed: 2006-09-11
Abstract: The present invention relates to a method of production and the use of a compositional ingredient. Specifically, the present invention relates to hydrosoluble stable organic salts of creatine and pyroglutamic acid. The compositional ingredient may be useful for the regulation of athletic and cognitive functions.
Patent CA-2561934-A1 (CA)
Title: System and method for capacity control in a multiple compressor chiller system
Inventor: CRANE CURTIS CHRISTIAN
IPC: F25B49/02
Filed: 2005-04-11
Abstract: A capacity control algorithm for a multiple compressor liquid chiller system 300 is provided wherein the speed and number of compressors 302, 303 in operation are controlled in order to obtain a leaving liquid temperature setpoint. In response to an increase in the load in the chiller system 300, the algorithm determines if a compressor 302, 303 should be started and adjusts the operating speed of all operating compressors 302, 303 when an additional compressor 302, 303 is started. In response to a decrease in the load in the chiller system 300 with multiple compressors 302, 303 operating, the algorithm determines if a compressor 302, 303 should be de-energized and adjusts the operating speed of all remaining operating compressors 302, 303 when a compressor 302, 303 is de-energized.
Patent CA-2562013-A1 (CA)
Inventor: GOLSHAN ALI
IPC: H04L45/18
Filed: 2005-04-05
Abstract: A virtual network device sub-unit (122(1), 122(2)) includes an interface (320(1), 320(2), 320(3), 320(4)) to a virtual network device link (360) and a distributed forwarding module (312(1), 312(2)). The interface (320(1), 320(2), 320(3), 320(4)) receives a packet, and the distributed forwarding module (312(1), 312(2))forwards the packet received by the interface (320(1), 320(2), 320(3), 320(4)). The distributed forwarding module (312(1), 312(2)) performs an ingress lookup if the packet includes a multicast destination address and an egress lookup if the packet includes a unicast destination address. If the packet includes a multicast destination address, the distributed forwarding module replicates the packet for each of several outgoing VLANs associated with the multicast destination address. If an additional multicast packet is received via an interface (320(1), 320(2), 320(3), 320(4)) that is not coupled to a virtual network device link (306), the distributed forwarding module (312(1), 312(2)) sends at most one copy of the additional multicast packet via the virtual network device link (360).
Patent CA-2562641-A1 (CA)
Inventor: BLAAKMEER ANTON
IPC: A01G31/02
Filed: 2005-04-29
Abstract: The invention provides a method of growing plants comprising supplying water to the plants so that the plant roots contact a body of water and drawing water through a suction device provided in contact with the body of water and into a first conduit (4) connected at one end to the suction device and through the first conduit (4) into a second conduit (5) connected to the other end of the first conduit (4), and the second conduit (5) is at least partially filled with air and the water is released from the first conduit (4) into air space in the second conduit (5), characterized in that the suction device is formed from a foam formed from a polymer selected from phenol urea formaldehyde; urea melamine formaldehyde polymer; polyurethane; furanic polymers; and homopolymers, copolymers and terpolymers of ethylene, propylene and butylene, provided that methods in which the plants are grown in a phenol urea formaldehyde foam growth substrate and the suction device is formed from phenol urea formaldehyde foam are excluded. The invention also provides an apparatus suitable for carrying out the method.
Patent CA-2566006-A1 (CA)
Title: Motor and gear unit assembly
Inventor: LEIMANN DIRK OLAF
IPC: H02K5/00
Filed: 2005-05-03
Abstract: A motor and gear unit assembly comprising a gear unit, a motor and a structural connector to which the gear unit and motor are secured, said structural connector being of a substantially elongate shape which extends substantially parallel with the rotational axis of a transmission member which interconnects the axially spaced motor and gear unit, said structural connector having at least a part which is substantially planar and which, in use, is orientated to lie in a substantially vertical plane, one of the gear unit end and motor end of the structural connector being a supported end which is secured to or adapted for securing to supporting structure and the other of the gear unit end and motor end of the structural connector being secured or securable relative to said supporting structure substantially solely by the length of said elongate structural connector between the supported end and said other of the gear unit end and motor end, wherein the motor has a primary direction of rotation, and the motor and gear unit are secured to that side of the structural connector which, in use, with the motor rotating in said primary direction, results in the structural connector experiencing a reactive torque which acts in a direction opposite to the torsional load transmitted along the length of the structural connector to the supported end due to the weight of said motor or gear unit acting at a centre of gravity position displaced horizontally from the plane of said structural connector.
Patent CA-2569082-A1 (CA)
Title: Adhesive composition, method for bonding to a metal surface and rubber to metal adhesive
Inventor: TALLMADGE JACK N
IPC: C09J11/04
Filed: 2005-06-16
Abstract: Disclosed is a rubber-metal adhesive in the form of dispersed solids in a volatile liquid carrier, with a specified pigment grind and is sprayable at uniform film coatings on metal surfaces at 25±2 solids content wt. % and a viscosity of from 50 to about 500 cps (Brookfield LVT 2 @ 30 rpm). The adhesive comprises a dispersion of solid particles comprising nitroso compound, halogenated polyolefin, acid acceptor and from 5% to 35 wt. % of inert, incompressible, spheroidal particles having a BET surface area of from 0.1 to 10 m<SUP>2</SUP>/g and a 50<SUP>th </SUP>percentile particle diameter (D<SUB>50</SUB>) of 5 to 25 mum.