baber/WOPTO huggingface dataset:
Patent FI-941343-A0 (FI)
Inventor: FRANZ LOTHAR
IPC: C09K23/16
Filed: 1994-03-23
Abstract: Halogen-free fuel additives based on a long-chain hydrocarbon containing a polar terminal group, obtained by recting a hydroformylated olefin with a polyamine and hydrogenating the reaction product.
Patent FI-946058-A0 (FI)
Inventor: GROSS UDO
IPC: A61Q19/00
Filed: 1994-12-23
Abstract: The invention relates to pharmaceutical compositions which are incorporated into the skin with the aid of novel microaggregates as carriers. The object of the invention is to make available pharmacological active compounds in a biologically and chemically inert carrier for therapeutic and diagnostic administration to the skin or for systemic administration, and in this way to make deeper penetration into the skin or transdermal transport possible. According to the invention, this is effected by means of a pharmaceutical composition for topical administration, which contains asymmetric lamellar aggregates, consisting of phospholipids, pharmacological active compounds and fluorocarbons or fluorocarbon mixtures, the proportion of fluorocarbon being in the range from 1 to 100% weight/volume, in a pharmaceutical excipient which is suitable for topical administration. Preparation is effected by emulsification of the appropriate constituents and use in ointments, creams, lotions, pastes, gels, powders or on a dressing or plaster or by means of a spray.
Patent FI-954438-A0 (FI)
Inventor: SOHAR PAUL
IPC: C07D335/00
Filed: 1995-09-20
Abstract: A key step in the synthesis of 5,6-dihydro-(S)-4-(ethylamino)-(S)-6-methyl-4H-thieno[2,3-b]thiopyran- 2-sulfonamide 7,7-dioxide (dorzolamide) and related compounds is a Ritter reaction with an unexpected tendency to proceed with retention of chirality.
Patent FI-961494-A0 (FI)
Inventor: MALLET JACQUES
IPC: C12N7/01
Filed: 1996-04-03
Abstract: Use of a cpd. (A) that at least partly inhibits the activity of p53 protein to prepare a compsn. for treating and/or preventing neurodegenerative diseases is new. Also claimed is recombinant virus contg., inserted in its genome, nucleic acid (a) encoding a mutated form of p53 able to antagonise p53 activity; (b) contg. all or part of the p53 binding site and/or (c) encoding antisense material able to reduce p53 expression at translational or transcriptional levels.
Patent IL-81275-A0 (IL)
Title: Submarine weapon handling system
IPC: F41A9/09
Filed: 1987-01-15
Abstract: <PAR>A submarine weapon handling system (28) and method includes a storage tray, ramming tray, and transfer tray. Each tray has a plurality of rotatable bands received in grooves in the trays and are movable between an open weapon receiving position and a closed weapon clamping position. The storage tray and ramming tray are stationary and the transfer tray is movable. The transfer tray is moved into contact with a weapon secured in the storage tray, the bands of the transfer tray are rotated around the weapon, and the bands in the storage tray are rotated from closed to open position permitting the transfer tray to move a selected weapon into the bands of the ramming tray which are then rotated into weapon clamping position while the bands of the transfer tray are opened permitting the transfer tray to be moved away from the ramming tray.
Patent IL-94808-A0 (IL)
Title: Sweeping implement and method of manufacture thereof
IPC: A47L13/38
Filed: 1990-06-20
Abstract: A broom (10) is disclosed comprising an elongated head (12) having an upper surface and a lower surface, a socket (14) on the upper surface for attaching the head to a broomstick, and bristles (16) projecting from the lower surface, wherein the head (12), the socket (14) and the bristles (16) are in the form of an integral moulding of a polymeric material and wherein the socket (14) is provided with resiliently flexible retaining means (22) on its inner surface for counteracting the removal of the broomstick from the socket. Some of the bristles (16) may conveniently be of smaller diameter and others may conveniently be of larger diameter. The polymeric compound may comprise rubber and may be pre-formulated such that, upon vulcanization, the sweeping implement has a Shore hardness, as measured on the A scale, of between 35 and 65 and an elongation at break of between 550% and 650%.
Patent IL-96707-A0 (IL)
Title: Controlled release pharmaceutical preparation and its production
IPC: A61K9/58
Filed: 1990-12-18
Abstract: A controlled release pharmaceutical preparation comprising (a) a core containing a pharmaceutically active substance and an organic acid, and (b) a coating film formed on the surface of the core by aqueous coating of a water-insoluble and slightly water-permeable acrylic polymer containing a trimethylammonium-ethyl group, which exhibits well controlled dissolution and release of the pharmaceutically active substance when administered and can maintain the desired blood level of the active substance for a long period of time, and a method for producing the preparation.
Patent FI-20022018-A0 (FI)
Inventor: ENQVIST RAUNO
IPC: D21F1/00
Filed: 2002-11-12
Abstract: The invention relates to a drying wire which is a 1.5-layer structure. The basic fabric of the wire comprises machine-direction yarns (1) and cross-machine direction yarns (2). Upon weaving, the web-side surface (B) is further provided with additional cross-machine direction yarns (3), which have an easily shapable structure in such a way that the additional yarns (3) can cover the spaces (4) formed between machine-direction yarns (1) on the web-side surface (B) substantially completely.
Patent FI-20030209-A0 (FI)
Inventor: OTTELIN JUHA
IPC: D21B1/38
Filed: 2003-02-12
Abstract: An arrangement for and a method of treating pulp, and a method of modernizing a pulp tower are disclosed. The arrangement and method relate to treating pulp in connection with high-consistency pulp towers, and especially to means (36, 42) for diluting pulp arranged substantially at the level of the smallest cross-sectional area between the parting member (31) and the wall (12) of the pulp tower (10).
Patent IL-105256-A0 (IL)
Title: Perhydroisoindole derivatives and their preparation
IPC: C07D209/44
Filed: 1993-04-01
Abstract: PCT No. PCT/FR93/00351 Sec. 371 Date Oct. 11, 1994 Sec. 102(e) Date Oct. 11, 1994 PCT Filed Apr. 8, 1993 PCT Pub. No. WO93/21154 PCT Pub. Date Oct. 28, 1993.This ivention relates to novel perhydroisoindole derivatives having formula (I),    <IMAGE>  (I)  wherein the symbols R, which are the same or different, are phenyl radicals optionally 2- or 3-substituted by a halogen atom or a methyl radical, R' is a phenyl radical optionally 2-substituted by a C1-2 alkylk or alkyloxy radical, R'' is a fluorine atom or a hydroxy radical, and R''' is a hydrogen atom, or else R' and R''' are hydroxy radicals, or R'' and R''' together form a bond, and Ro is a hydrogen atom or a protective radical; salts thereof whereever applicable; and preparation thereof. These products are synthetic intermediates for the preparation of derivatives having P substance antagonist activity.
Patent IL-109016-A0 (IL)
Title: Inhibitor of vascular endothelial cell growth factor
IPC: C12P21/00
Filed: 1994-03-17
Abstract: The vascular endothelial cell growth factor (VEGF) inhibitors of the present invention are naturally occurring or recombinantly engineered soluble forms with or without a C-terminal transmembrane region of the receptor for VEGF, a very selective growth factor for endothelial cells. The soluble forms of the receptors will bind the growth factor with high affinity but do not result in signal transduction. These soluble forms of the receptor bind VEGF and inhibit its function.
Patent IL-121070-A0 (IL)
Title: Liposome formulations of 5beta steroids
IPC: A61K31/565
Filed: 1996-09-27
Abstract: Liposome preparations which comprise a lipid, or lipid like compound and a 5beta steroid, DHEA or an organic acid derivative of the 5beta steroid or DHEA are described. The lipsome may also include an entraped aqueous portion which comprises dissolved therein the expression product of the ob gene. Methods for treating conditions including obesity,hypercorticoidism and diabetes using the liposome preparations are also claimed.
Patent IL-124917-A0 (IL)
Title: Medical valve with resilient seal
Inventor: LOPEZ GEORGE A
IPC: A61M39/26
Filed: 1996-12-16
Abstract: A medical valve has a body which includes a wall structure defining an internal cavity having a proximal end and a distal end. The proximal end has an opening sufficiently large to receive a tip of a delivery end of a medical implement which transfers fluid through the delivery end. The valve also has a spike with a tip contained within the cavity and at least one hole located distal the tip. The spike has a passageway in communication with the hole that allows fluid to flow through the spike. The valve also has a resilient seal in the cavity which surrounds the spike. The seal is adapted to be moved into a compressed state upon insertion of the tip of the medical implement into the opening. The seal is sufficiently resilient to return to a decompressed state upon removal of the tip of the medical implement from the opening. In addition, the seal has at least two tires in contact with the spike proximal the hole, preventing the flow of fluid through the valve when the seal is in the decompressed state.
Patent IL-128870-A0 (IL)
Title: Pharmaceutical compositions for treating fungal infections
IPC: A61P31/00
Filed: 1997-09-09
Abstract: There is described antifungal combination therapy comprising the use of known antifungal agents such as the azoles or polyenes in combination with a pneumocandin derivative antifungal agent. More particularly, the invention relates to antifungal combination therapy comprising the use of azoles such as fluconazole, voriconazole, itraconazole, ketoconazole, miconazole, ER 30346, SCH 56592;polyenes such as amphotericin B, nystatin or liposomal and lipid forms thereof such as Abelcet, AmBisome and Amphocil; purine or pyrimidine nucleotide inhibitors such as flucytosine; or polyoxins such as nikkomycins, in particular nikkomycin Z or other chitin inhibitors, elongation factor inhibitors such as sordarin and analogs thereof, mannan inhibitors such as predamycin, bactericidal/permeability-inducing (BPI) protein products such as XMP.97 or XMP.127 or complex carbohydrate antifungal agents such as CAN-296 in combination with a pneumocandin derivative as described herein.
Patent IL-132156-A0 (IL)
Title: Neoglycoproteins
IPC: C07H15/04
Filed: 1998-04-16
Abstract: Polyamide conjugates comprising either (a) a xenoantigenic group; or (b) a biologically active group and a macromolecular, macro- or microscopic entity; bound to a polyamide backbone, processes for their preparation and the use of these conjugates in therapeutic compositions.
Patent IL-146034-A0 (IL)
Title: High mass transfer electrosprayer
IPC: A61M1/26
Filed: 2000-04-20
Abstract: A electrohydrodynamic aerosol sprayer wherein a gas flow deflector is used for creating a gas flow past the spray nozzle to stabilize the Taylor cone and to transport at least a portion of the aerosol away from the region downstream of the spray nozzle. This stabilization of the cone and transport of aerosol improves the droplet size and distribution and may also reduce the deposit of droplets on the internal components of the device.
Patent IL-146570-A0 (IL)
Title: Modular clean room filter system
IPC: E04B9/18
Filed: 2001-01-03
Abstract: An air filter system for a clean room is comprised of a number of filter modules (16) secured together at intersecting corners by holding rods (12) secured to a supporting surface, and at least one support bracket (14, 14', 14") on each holding rod. The filter modules include top panels (18, 18'), that if separable, are secured to upper brackets and a filter element (19), having a rigid frame (21) and filter panels (27) held therein secured to lower brackets. Light fixtures (38) may be secured to center divider (40) held in the filter frames and diffuser panels (50) or aerodynamically-shaped elements (60) may be secured to the support brackets, below the filter elements.
Patent IL-151928-A0 (IL)
Title: Rna sequence-specific mediators of rna interference
IPC: C07H/
Filed: 2001-03-30
Abstract: The present invention relates to a Drosophila in vitro system which was used to demonstrate that dsRNA is processed to RNA segments 21-23 nucleotides (nt) in length. Furthermore, when these 21-23 nt fragments are purified and added back to Drosophila extracts, they mediate RNA interference in the absence of long dsRNA. Thus, these 21-23 nt fragments are the sequence-specific mediators of RNA degradation. A molecular signal, which may be their specific length, must be present in these 21-23 nt fragments to recruit cellular factors involved in RNAi. This present invention encompasses these 21-23 nt fragments and their use for specifically inactivating gene function.; The use of these fragments (or chemically synthesized oligonucleotides of the same or similar nature) enables the targeting of specific mRNAs for degradation in mammalian cells, where the use of long dsRNAs to elicit RNAi is usually not practical, presumably because of the deleterious effects of the interferon response. This specific targeting of a particular gene function is useful in functional genomic and therapeutic applications.
Patent IL-162001-A0 (IL)
Title: Catheter injectable depot compositions and uses thereof
IPC: A61K9/06
Filed: 2002-11-14
Abstract: Catheter injectable depot compositions are provided that include a bioerodible, biocompatible polymer, a solvent having miscibility in water of less than or equal to 7 wt. % at 25° C., in an amount effective to plasticize the polymer and form a gel therewith, a thixotropic agent, and a beneficial agent. The solvent comprises an aromatic alcohol, an ester of an aromatic acid, an aromatic ketone, or mixtures thereof. The compositions are have substantially improved the shear thinning behavior and reduced injection force, rendering the compositions readily implanted beneath a patient's body surface by injection.
Patent IL-172920-A0 (IL)
Title: Method and means of multi-activation of ions and atoms with nmr and epr
IPC: G01R33/32
Filed: 2005-12-29
Abstract: The invention uses one inductor, which is formed of one, two or a few twisted or parallel conductors, and exposes a sample object in a pulsed and damped alternating magnetic field (B) without necessarily the employment of a second, constant intensity, magnetic field. In this way, the nuclei and/or the electrons of the sample object are activated, in the presence of a non-constant magnetic field (B), that gets infinite negative and positive values between successive damped positive and negative values, crossing through the zero value during a magnetic pulse. Thus, a wide nuclear NMR and electronic EPR multiple-resonance of the sample object is achieved.
Patent IL-172941-A0 (IL)
Title: Methods and systems for inspection of wafers and reticles using designer intent data
IPC: G03F7/20
Filed: 2006-01-02
Abstract: Methods and systems for inspection of wafers and reticles using designer intent data are provided. One computer-implemented method includes identifying nuisance defects on a wafer based on inspection data produced by inspection of a reticle, which is used to form a pattern on the wafer prior to inspection of the wafer. Another computer-implemented method includes detecting defects on a wafer by analyzing data generated by inspection of the water in combination with data representative of a reticle, which includes designations identifying different types of portions of the reticle. An additional computer-implemented method includes determining a property of a manufacturing process used to process a wafer based on defects that alter a characteristic of a device formed on the wafer. Further computer-implemented methods include altering or simulating one or more characteristics of a design of an integrated circuit based on data generated by inspection of a wafer.
Patent IL-180958-A0 (IL)
Title: Lysine based compounds
Filed: 2007-01-25
Abstract: The present invention provides lysine based compositions which include both an HIV antiviral or anti-retroviral agent and a compound of the formula;   
wherein R 1  may be, for example, (HO) 2 P(O)-, (NaO) 2 P(O)-, alkyl-CO- or cycloalkyl-CO-, wherein X and Y may be, for example, H, alkyl, cycloalkyl, F, Cl, Br, I or any of a range of other defined functional groups, wherein n is 3 or 4 and wherein R 2  , R 3  and R 6  are as defined herein.
Patent IL-189683-A0 (IL)
Title: Electromuscular incapacitation device and methods
Filed: 2008-02-21
Abstract: Incapacitation of a mammalian subject results from the application of a pulsed, low- power electric waveform. The waveform is applied to the subject at a frequency and over a time period sufficient to induce involuntary muscular contraction. Additionally, the contraction causes limited lactic acid production and is non- or minimally-injurious to the subject's tissues. A device utilizing such a waveform is designed to control or otherwise subdue an individual.
Patent IL-192218-A0 (IL)
Title: Preparation of brominated styrenic polymers or resins
Filed: 2008-06-16
Abstract: Bromination of styrenic polymer is carried out in a closed reaction system to retain HX coproduct (where HX is HBr or HCl, or both) in the bromination reaction mixture at superatmospheric pressure. Preferably, the reaction mixture which includes the brominated styrenic polymer and substantially all of the HX coproduct formed is discharged into an aqueous quenching medium. By operating in this manner, the reaction is terminated and the brominated styrenic polymer of desired bromine content and substantially all HX coproduct are captured in the same operation, process equipment costs are reduced, and processing of the reaction mixture is facilitated.
Patent IL-193393-A0 (IL)
Title: Hybrid impact modifiers and method for preparing the same
Filed: 2008-08-12
Abstract: The present invention relates to hybrid impact modifiers prepared by: either spray drying, coagulation, freeze coagulation or other known recovery methods of a mixture of a latex or slurry of standard impact modifiers and a slurry of a mineral filler, or simultaneous drying (by spray-drying, coagulation other known recovery possible methods) of (i) a latex or slurry of standard impact modifiers and of (ii) a slurry of a mineral filler, further to the coagulation or freeze coagulation, if any, there is a filtration and drying step to recover these hybrid impact modifiers as a powder. The present invention also relates to the use of said hybrid impact modifiers in thermoplastic polymers, and a thermoplastic polymer containing said hybrid impact modifiers. The hybrid impact modifiers may exhibit improved powder properties (flowability, lumping/caking resistance, segregation between the organic and the mineral parts) and better dispersion homogeneities.
Patent IL-197188-A0 (IL)
Title: Treating mycobacterial infections with cyclipostins
Filed: 2009-02-23
Abstract: The invention refers to the use of a compound of the formula (1)   
for the treatment of bacterial infections caused by mycobacteria and related microorganisms, such as tuberculosis, leprosy, nocardiosis, diphtheria, pulmonary mycobacterial infection, cutaneous mycobacterial infection, atypical mycobacterial infection and mycobacteriosis.
Patent IL-197388-A0 (IL)
Title: Method using radar to detect a known target likely to be positioned at approximately a given height, near other targets postioned at appaoximately the same height
Filed: 2009-03-03
Abstract: The method involves detecting a target i.e. beacon (2), by carrying out azimuth scanning. The target is detected along an azimuth angle (theta-az) and along an elevation angle corresponding to an elevation angle of an object arranged at distance (Di) and specific height, when the target is detected at the distance along the azimuth angle. The target is reputedly detected, if the target is detected along the elevation angle at distance (D) that is equal to the distance (Di). An independent claim is also included for a method for locating a beacon with a radar.
Patent IL-221708-A0 (IL)
Title: Polyclonal goat anti-hla class ii antibody for treatment of disease involving proliferative immune response
IPC: C07K16/10
Filed: 2012-08-30
Abstract: Anti-HLA and other antibodies are present in goat serum after injection of HIV antigenic material, and form the basis for a most surprisingly effective treatment of HIV, multiple sclerosis and other conditions.
Patent RO-128286-A0 (RO)
Title: Modular stair elevator
Inventor: ANDRES TEOFIL NUTU
IPC: B66B9/08
Filed: 2012-06-15
Abstract: The invention relates to a modular stair lift, which is mounted on the stairs of a construction, for being used by persons with locomotor or other dysfunctions. According to the invention, the lift consists of a driving and transporting module (), which carries one of the seating modules (), in multiple constructive variants, conceived for various weights or positions of the carried person and which shows, between itself and an optional seating module (), depending on the stairs construction, an auxiliary descending module (), the driving and transporting module () carrying a travelling carriage (), which supports, in its turn, some displacing rollers, supported by a box () and shows a stabilizer () which comprises a body (), wherethrough there passes a rod () mounted with a spring (), which is fastened on a pressure plate (), having a mobile part in mechanical contact with a surface () of an arm () and when between the arm () and a lower pipe () there are formed angles tending to 90°, the arm () presses the rod () which compresses the spring () and the more the angle between the arm () and the pipe () approaches closer to 90°, the higher and higher is the force applied, in opposite sense, upon another arm (), so that the wedging effect is completely eliminated, the carriage () supporting the rollers consisting of a main flat support () whereon there are fastened a body () and the box (), any of the seating modules () being mounted on the carrying module () by means of some connectors placed in front of some orifices machined in a plate () of the stabilizer ().
Patent RO-133869-A0 (RO)
Title: Personal anti-sedentary behaviour system
Inventor: ŢÎŢU MIHAIL AUREL
IPC: A47C9/02
Filed: 2019-10-21
Abstract: The invention relates to a piece of furniture which replaces persons' long motionless sitting while watching TV and working at the computer, with a sitting providing a continuous mobility of the human body skeletal structure. According to the invention, the piece consists of a chair having an ergonomic seat (1) placed above a base plate (9) fixed to a telescopic leg (4) which rolls on some swinging rollers, between the seat (1) and the base plate (9), there being an electro-mechanical oscillating assembly (6) provided with a linear electric actuator (29), which imparts two simultaneous continuous oscillating movements to the seat (1), one of left-right inclination by 4° related to the horizontal and the other of rotation in the horizontal plane by an angle of 10° related to a median position, the repeated linear movement of the actuator (29) being converted into two angular movements of the seat (1) by means of a central hub (22), placed around a self-aligning bearing (12), such as a double-row ball-bearing, the hub (22) having four semi-axes (16, 17, 18 and 19) provided with bearings at the ends, which are radially placed around it, in quadrature.
Patent AP-2002002707-A0 (AP)
Title: 4, 5-Dihydro-Thiazo-2-Ylamine Derivatives and their Use as NO-Synthase Inhibitors.
Inventor: DAMOUR DOMINIQUE
IPC: A61P25/06
Filed: 2001-06-07
Abstract: The invention concerns pharmaceutical compositions containing as active principle a 4,5-dihydro-1,3-thiazol-2-ylamine of formula (1) wherein: R represents an -alk-S-alk-Ar, phenyl or phenyl radical substituted by alkoxy or halogen or one of its pharmaceutically acceptable salts, the novel derivatives of formula (1) and their preparation. Said compounds are useful for preventing and treating diseases wherein is involved arbnormal production of nitrogen monoxide (NO) by induction of inducible NO-synthase (NOS-2)