baber/WOPTO huggingface dataset:
Patent NZ-266234-A (NZ)
Title: Process for purifying a plasma protein employing a salt to form vesicles containing virus-inactivating chemicals; the vesicles are then removed
Inventor: ISAKSSON SVEN
IPC: C07K14/81
Filed: 1994-05-06
Abstract: PCT No. PCT/SE94/00422 Sec. 371 Date Oct. 30, 1995 Sec. 102(e) Date Oct. 30, 1995 PCT Filed May 6, 1994 PCT Pub. No. WO94/26287 PCT Pub. Date Nov. 24, 1994Virus inactivating chemicals and/or detergents in an aqueous composition containing a water-soluble plasma protein are reduced by selecting a suitable combination of temperature and concentration above 0.5M of salt with a high salting out effect according to the Hofmeister series, thereby forming vesicles containing the virus inactivating chemical and/or detergent. These vesicles are removed from the aqueous phase, e.g. by phase separation or filtration, and the protein thereafter isolated from the aqueous phase. The water-soluble plasma protein can be e.g. antithrombin III, transferrin or albumin. When the aqueous phase comprises e.g. a salt of citrate or sulphate in a concentration above 1M at room temperature, the reduction of virus inactivating chemical or detergent can be as high as 2000 times or more, giving a final concentration below 5 ppm.
Patent NZ-271091-A (NZ)
Title: 15,15-dialkylestra-1,3,5(10)-triene-3,17<beta>-diol derivatives; 17-keto or -(h,oh) intermediates
Inventor: BULL JAMES RONALD
IPC: C07J1/00
Filed: 1994-08-01
Abstract: New 15,15-dialkyl-substituted derivatives of the estradiol of general formula I    <IMAGE>  (I)  in which R1 and R2, independently of one another, are each a hydrogen atom or a straight-chain alkanoyl group with 1 to 10 carbon atoms, a branched-chain alkanoyl group with 3-10 carbon atoms, an alkanoyl group of 3-10 carbon atoms containing a cycloaliphatic structure of 3-6 carbon ring atoms or a benzoyl group, and R3 and R4, independently of one another, are each a straight-chain alkyl group with 1 to 10 carbon atoms or a branched-chain alkyl group with 3 to 10 carbon atoms, are described, a process for their production and initial products for this process. The new compounds have-also after oral administration-high estrogenic effectiveness and are suitable for the production of pharmaceutical agents.
Patent NZ-305268-A (NZ)
Title: Detergent cleaning composition comprising diacyl peroxide particulates, and preparation thereof
Inventor: PAINTER JEFFREY DONALD
IPC: C11D3/395
Filed: 1996-03-27
Abstract: There is provided a process for ma ing composite particulates comprising from about 1% to about 50% by weight of discrete particles of water-insoluble diacyl peroxide having a mean particle size of less than about 300 microns and from about 30% to about 99% by weight of a carrier material which melts in the range of from about 38 DEG  C. to about 77 DEG  C. This preparation process involves the steps of (i) mixing the particles of water-insoluble diacyl peroxide into the carrier material while the carrier material is in a molten state and then (ii) rapidly cooling and solidifying the resultant mixture and thereafter (iii) wor ing the solidified mixture if or as necessary to form the composite particulates therefrom. Detergent compositions containing the composite particulates are also provided.
Patent NZ-310729-A (NZ)
Title: Recombinant production of novel polyketides and polyketide synthases using a host vector system and a combinatorial biosynthesis of polyketides
Inventor: KHOSLA CHAITAN
IPC: C12P17/16
Filed: 1996-06-05
Abstract: Novel polyketides and novel methods of efficiently producing both new and known polyketides, using recombinant technology, are disclosed. In particular, a novel host-vector system is described which is used to produce polyketides synthases which in turn catalyze the production of a variety of polyketides.
Patent NZ-329133-A (NZ)
Title: Benzothiazolin-2-one or benzoxazolin-2-one derivatives with a n-hetring-methyl substituent attached to the benzo ring
Inventor: LESIEUR DANIEL
IPC: A61K31/495
Filed: 1997-11-07
Abstract: Amino methyl heterocyclic derivatives of formula (I), their isomers and salts, are new. R1 = H, 1-6C alkyl or a group of formula (a); m = 1-4; Ar1 = COAr2 or =C-(Ar2)2; Ar2 = phenyl optionally substituted by 1 or more halo, OH, 1-6C alkyl, 1-6C alkoxy or CF3; n = 0-1, A = O or S; X = CH2 or a bond; Y = CH or N; Ar = phenyl or naphthyl (optionally substituted by 1-3 halo, OH, 1-6C alkyl, 1-6C alkoxy, CF3 or aminosulphonyl), pyridyl, pyrimidyl or 3-(benzoÄdÜ-1,2-thiazolyl).
Patent NZ-332958-A (NZ)
Title: Filter apparatus including a housing, disc filters and conduit from filters to output
Inventor: GOULD WARRICK STEVEN
IPC: C02F3/00
Filed: 1998-11-23
Abstract: A filter includes a housing 14 with apertures 12 in a side wall for effluent input from a septic tank, closely adjacent discs 16, with effluent breakdown bacteria living on the surfaces, located on the central shaft 11a and an output 13 through a wall at the upper end for treated effluent.  A central shaft extends through a lid 11 to form an extendable handle 11a for ease of removing the disc cluster from the housing.  Effluent entering through the input 12 is restricted to follow a path through the disc cluster into the central shaft via slits 17 to the output.
Patent NZ-334589-A (NZ)
Title: Aqueous two-phase system for purifying apolipoproteins
Inventor: AGELAND HANS
IPC: C12N15/09
Filed: 1997-09-08
Abstract: The first step in the process for purifying an amphiphilic compound is to mix a starting material containing the amphiphilic compound with a first polymeric material, water and at least one of a second polymeric material and a surfactant.  The first polymeric material and the second polymeric material and/or surfactant are immiscible in the resulting primary aqueous solution. The primary aqueous solution is maintained for a period of time sufficient for separating the phases formed.  The phase containing the main portion of the amphiphilic compound and the second polymeric material and/or surfactant is removed. The second polymeric material and/or surfactant are separated from the amphiphilic compound, and subsequently recycled to the initial mixing step. This process can be used in the purification of apolipoprotein A (ApoA) or apolipoprotein E (ApoE).
Patent NZ-335757-A (NZ)
Title: Polyolefins having greater than 5 percent 2-hydroxyethyl methacrylate grafted thereto
Inventor: SCHERTZ DAVID MICHAEL
IPC: C08L51/06
Filed: 1997-09-30
Abstract: Provided is melt grafting 2-hydroxyethyl methacrylate onto polyethylene and polypropylene resins and processes for preparing such polymers.  Specifically, provided is a modified polyolefin composition includes from about 70 to 95 weight percent of a polyolefin homopolymer, and from about 5 to 30 weight percent of 2-hydroxyethyl methacrylate grafted o the polyolefin homopolymer, wherein the polyolefin homopolymer has a number average molecular weight of greater than about 40 000g/mol, and wherein the modified polyolefin composition is substantially soluble in xylenes and wherein the modified polyolefin composition is capable of being extruded into a film.
Patent NZ-336804-A (NZ)
Title: Use of pramipexole in the treatment of restless legs syndrome
Inventor: OERTEL WOLFGANG H
IPC: A61K31/425
Filed: 1998-01-16
Abstract: Described is the use of 2-amino-6-n-propylamino-4,5,6,7-tetrahydrobenzothiazole (Pramipexole) in the manufacture of a medicament for treating restless legs syndrome.
Patent NZ-502129-A (NZ)
Title: Cloning using donor nuclei from non-serum starved, differentiated cells
Inventor: STICE STEVEN L
IPC: A61K35/12
Filed: 1998-06-24
Abstract: A method of cloning a non-human mammal comprising: (i) inserting a desired non-serum starved, differentiated mammalian cell or cell nucleus into an enucleated mammalian oocyte of the same species as the differentiated cell or cell nucleus under conditions suitable for the formation of a nuclear transfer (NT) unit; (ii) activating the resultant nuclear transfer unit; and (iii) transferring the cultured NT unit to a host mammal such that the NT unit develops into a fetus; a method of producing a CICM cell line; differentiated cells obtained by this method; and the use of the differentiated cells for the preparation of a composition for therapeutic treatment of a patient in need of cell transplantation therapy, wherein the therapy may be effected to treat a disease or condition selected from Parkinson's disease, Huntingdon's disease, Alzheimer's disease, ALS, spinal cord defects or injuries, multiple sclerosis, muscular dystrophy, cystic fibrosis, liver disease, diabetes, heart disease, cartilage defects or injuries, burns, foot ulcers, vascular disease, urinary tract disease, AIDS and cancer.
Patent NZ-504278-A (NZ)
Title: Valve and seat for feeding teat with flap(s) and seat
Inventor: CROSSLEY DESMOND
IPC: F16K7/18
Filed: 2000-05-03
Abstract: The valve consists of element 11 with slits 15a, 15b placed face to face with element 12 having apertures 16. Area 17 of element 12 has engagement means 17 (typically the cross shaped area) aligned with the slits. Elements 11, 12 are located at an inlet end of feeding teat T.
Patent NZ-505924-A (NZ)
Title: Heteroaryl-substituted pyrrole derivatives and pharmaceuticals thereof, and their use for the treatment or prophylaxis of diseases which can be treated or prevented by inhibiting the production of inflammatory cytokines in a mammal
Inventor: NAKAO AKIRA
IPC: C07D453/02
Filed: 2000-07-21
Abstract: A compound of formula (I), or a salt, ester or other derivative thereof, wherein: A is a pyrrole ring. R1 is optionally substituted aryl or optionally substituted heteroaryl. R2 is optionally substituted heteroaryl having at least one nitrogen atom. R3 represents the group -X-R4, wherein: X is a single bond, optionally substituted alkylene, optionally substituted alkenylene, optionally substituted alkynylene. R4 is substituted cycloalkyl, substituted aryl, optionally substituted heteroaryl or a group of formula -NRaRb. The variables Ra, Rb, aryl, heteroaryl, alkylene, alkenylene, alkynylene, cycloalkyl and all substituents are as defined in the specification. Provided that in the compound of formula (I), the substituents R1 and R3 are bonded to the two atoms of the pyrrole ring which are adjacent to the atom on the pyrrole ring to which the R2 substituent is bonded.  Also described is a pharmaceutical composition that comprises the compound of formula (I) together with a carrier or diluent. The compounds of formula (I) can be used for the treatment or prophylaxis of diseases that can be treated or prevented by inhibiting the production of inflammatory cytokines in a mammal. The compounds of formula (I) can be used for: inhibiting bone resorption, treatment or prophylaxis of inflammatory diseases, treatment or prophylaxis of viral diseases, relief of pain or pyrexia, or for the treatment or prophylaxis of: arthritis, cancer, hepatitis, allergic diseases, septicaemia, psoriasis, osteoporosis, ulcerative colitis, diabetes, nephritis, ischemic heart disease, Alzheimer's disease and arteriosclerosis.
Patent NZ-507693-A (NZ)
Title: Medicaments containing reboxetine for the treatment of obsessive compulsive disorder and panic disorder
Inventor: DUBINI ADRIANA
IPC: A61K31/35
Filed: 1999-04-02
Abstract: Disclosed is the use of a therapeutically effective, non-toxic dose of reboxetine in the manufacture of a medicament for the treatment of a disorder selected from Obsessive Compulsive Disorder (OCD), and/or Panic Disorder (PD), in a patient in need thereof.
Patent NZ-514573-A (NZ)
Title: Beta-hydroxyalkylamides, process for their production and their use
Inventor: KAPLAN ANDREAS
IPC: C09D5/03
Filed: 2001-10-02
Abstract: b-hydroxyalkylamine having the general Formula 1, where R1 is H or a linear or branched C1 to C10 alkyl and R2 is a linear or branched C1 to C5 alkyl; and processes for it's production.
Patent NZ-525907-A (NZ)
Title: Use of the macrolides abamectin, ememectin or spinosad for contolling molluscs
Inventor: HOFER DIETER
IPC: A01N43/00
Filed: 1998-12-21
Abstract: A method for controlling molluscs, comprising applying the composition to the molluscs or their environment is disclosed. Also described are the following methods: (1) a method for controlling pests in transgenic crops, comprising applying the composition to the pests or their environment; (2) a method for protecting plant propagation material "and plant organs that grow at a later date" from attack by pests, comprising employing the composition "in the immediate spatial vicinity of, or spatially together with, the planting or use of the propagation material at the site of planting or sowings"; (3) a method for controlling wood pests, comprising applying the composition to the pests or their environment. Also disclosed is a composition for controlling wood pests and molluscs comprising an active pesticide containing at least one macrolide and at least one auxiliary. (62) Divided out of 505208
Patent NZ-525972-A (NZ)
Title: A lactonization process
Inventor: PICHA FRANTISEK
IPC: A61P3/06
Filed: 2002-03-11
Abstract: Disclosed herein is a process for synthesizing a compound of formula (1) comprising the steps of intramolecular esterification, lactonization, of a compound of formula (2) with a lactonization agent in a suitable solvent thus yielding a reaction medium, wherein R is a hydrogen atom or a lower alkyl group, preferably a methyl group and X is a hydrogen atom or a cation, wherein water released in the lactonization reaction of compound (2) into compound (1) complexes with the lactonization agent to form a hydrated complex of the lactonization agent, which hydrated complex is substantially insoluble in the solvent.
Patent NZ-528634-A (NZ)
Title: Pharmaceutically active uridine esters
Inventor: SUSILO RUDY
IPC: C07H/
Filed: 2002-04-29
Abstract: Disclosed are compounds of formula (I), wherein: R represents R"-COO; R' represents hydrogen or a hydroxy group; R" represents a alkyl chain with 8 to 30 carbon atoms, a monobranched or multibranched alkyl chain with 8 to 30 carbon atoms, a monoenoic alkyl chain with 8 to 30 carbon atoms, a monoenoic branched alkyl chain with 8 to 30 carbon atoms, a polyenoic alkyl chain with 8 to 30 carbon atoms, a polyenoic branched alkyl chain with 8 to 30 carbon atoms, a branched or unbranched alkyl chain with 8 to 30 carbon atoms containing a carbocyclic or heterocyclic ring, a monoinoic alkyl chain with 8 to 30 carbon atoms, a monoinoic branched alkyl chain with 8 to 30 carbon atoms, a polyinoic alkyl chain with 8 to 30 carbon atoms, a polyinoic branched alkyl chain with 8 to 30 carbon atoms, an alkyl chain with 8 to 30 carbon atoms containing at least one double and one triple bond, a branched alkyl chain with 8 to 30 carbon atoms containing at least one double and one triple bond, a hydroxy group or thiol group containing branched or unbranched and/or saturated or unsaturated alkyl chain with 8 to 30 carbon atoms. The compounds are used in the manufacture of medicaments for the treatment of various diseases, including diabetes mellitus Type I and Type II, inflammation, cancer and cardiovascular diseases.
Patent NZ-529335-A (NZ)
Title: A PDE 4 inhibitor and an anti-cholinergic agent in combination for treating obstructive airways diseases
Inventor: YEADON MICHAEL
IPC: C07D471/14
Filed: 2002-05-24
Abstract: An inhalable combination of a synergistically effective amount of a selective PDE4 inhibitor and an anticholinergic agent is disclosed, wherein the selective PDE4 inhibitor is 9-cyclopentyl-5, 6-dihydro-7-ethyl-3-(2-thienyl)-9H-pyrazolo[3, 4-c]-1, 2,4triazolo[4,3-a]pyridine or 9-cyclopentyl-5, 6-dihydro-7-ethyl-3-(tert-butyl)-9H-pyrazol[3,4-c]-1,2,4-triazolo[4,3-a] pyridine or a pharmaceutically acceptable salt or solvate thereof, with the proviso that the anticholinergic agent is not a tiotropium salt. These combinations are suitable for the treatment of obstructive airways and other inflammatory diseases, particularly the obstructive airways diseases asthma, chronic obstructive pulmonary disease (COPD) and other obstructive airways diseases exacerbated by heightened bronchial reflexes, inflammation, bronchial hyper-reactivity and bronchospasm.
Patent NZ-532725-A (NZ)
Title: Delta1-pyrrolines having insecticidal properties
Inventor: SEITZ THOMAS
IPC: A01N25/04
Filed: 2002-11-04
Abstract: Delta1-pyrrolines of formula (I) that have insecticidal properties and are suitable for use as pesticides to control pests in animals are disclosed, wherein R1, R2, Y and R3 are as defined in the specification. Several methods for the production of these delta1-pyrrolines are also disclosed.
Patent NZ-532852-A (NZ)
Title: Composition comprising and method of using angiopoietin-like protein 3 Angptl3
Inventor: FERRARA NAPOLEONE
IPC: A61K36/27
Filed: 2002-11-13
Abstract: The use of an Angpt13 antagonist which inhibits the interaction of Angpt13 with alpha-nu-beta-3 integrin, for the manufacture of a medicament for the treatment or prevention of liver disease.
Patent NZ-536291-A (NZ)
Title: Benzopyranone compounds, compositions thereof, and methods of treatment therewith
Inventor: MCKIE JEFFREY A
IPC: C07D311/16
Filed: 2003-04-18
Abstract: Disclosed are compounds of formula (I), wherein; n is 2, 3 or 4, R1 is H, C(=O)R2, C(=O)OR2, C(=O)NHR2, C(=O)NR2R3 or S(=O2)NR2R3, R2 and R3 are optionally substituted independently alkyl, aryl, arylalkyl, or a 5-6 membered heterocycle containing up to two heteroatoms selected from O, NR4 and S(O)q, R4 is H or alkyl, R5 is H, halogen, hydroxy, alkyl, alkoxy, acyloxy, thio, alkylsulfinyl, alkylsulfonyl, hydroxy-alkyl, aryl, aralkyl, COOH, CN, CONHOR6, SO2NHR6, NH2, alkylamino, dialkylamino, NHSO2R6, NO2 or a 5-6 membered heterocycle, X is H, halogen or trifluoromethyl, and Y is halogen or trifluoromethyl. The compounds are used for the manufacture of medicaments for inhibiting a cytokine in a patient.
Patent NZ-537078-A (NZ)
Title: System and method for the accurate collection of end-user opinion data for applications on a wireless network
Inventor: ROSS DAVID J
IPC: G06Q30/02
Filed: 2003-07-01
Abstract: A system, method, and computer program for collecting end-user opinions of applications and data in a wireless communications network. The system identifies the end-user who has downloaded software applications and/or data to a wireless device and collects end-user opinion preferably through the transmission of a targeted questionnaire to the wireless device.
Patent NZ-542769-A (NZ)
Title: Flow generator with ring shaped restriction member within conduit to increase gravity flow
Inventor: AGNEW WARREN ROY
Filed: 2003-04-04
Abstract: In order to increase gravitational flow rate through pipe 2 a ring shaped restriction 1 is inserted into the pipe, typically at least 1.5 metres below the top end of the pipe.
Patent NZ-542910-A (NZ)
Title: Use of safinamide and levodopa for making a medicament for treatment of Parkinson's disease
Inventor: RUGGERO FARIELLO
IPC: A61K45/06
Filed: 2004-04-08
Abstract: A use of (a) safinamide and (b) levodopa/PDI, for the preparation of a medicament for the treatment of Parkinson's Disease, wherein the medicament is formulated for separate, sequential or simultaneous administration of (a) and (b). The medicament may further comprise a catechol-O-methyltransferase inhibitor such as tolcapone or entacapone.
Patent NZ-548736-A (NZ)
Title: Non-disintegrating oral solid composition of high dose of water soluble drugs
Inventor: JAIN RAJESH
IPC: A61K9/24
Filed: 2005-01-05
Abstract: Disclosed are non-disintegrating, non-eroding, non-bioadhesive and non-swelling oral controlled release pharmaceutical compositions and a process for the preparation of such. The compositions comprise at least one high dose water soluble active ingredient, at least one diluent, at least one binder, and a polymer system comprising of at least one release controlling polymer. The compositions formulated into a suitable dosage form maintain their geometric shape even after the drug has diffused from the dosage form. The compositions provide concentrations of active ingredient above effective levels for extended periods of time, optionally with other pharmaceutically acceptable excipients. They preferably comprise an antibiotic as the active ingredient, preferably Amoxicillin or its pharmaceutically acceptable salts, hydrates, polymorphs, esters, and derivatives thereof. More preferably the active ingredient is amoxicillin sodium, either alone or in combination with one or more other antibiotics. Further disclosed are controlled release compositions which provide an initial burst release of approximately 20% - 40% of the active ingredient within one hour, for achieving blood levels equivalent to minimum inhibitory concentration, while maintaining these levels for an extended period of time.
Patent NZ-548819-A (NZ)
Title: Hand-held electronically controlled injection device for injecting liquid medications
Inventor: PONGPAIROCHANA VINCENT
IPC: A61M5/315
Filed: 2005-02-17
Abstract: A hand-held, electronically controlled injection device for injecting preset doses of a liquid medication, is disclosed. The injection device comprises a housing for receiving a medication container containing the liquid medication, a contact surface for contacting a patient's skin, and a first actuator for moving the medication container within the housing to and from the contact surface. The contact surface of the housing comprises a through opening for receiving a needle assembly. The injection device also includes a releasable retaining means for locking the needle assembly in a predetermined position engaging the opening, during displacement of the medication container towards the contact surface, from a first operating position, withdrawn inside the housing, to a second operating position, connected to a needle of the needle assembly.
Patent NZ-552592-A (NZ)
Title: Controlled release preparation
Inventor: AKIYAMA YOHKO
IPC: A61K9/20
Filed: 2003-10-15
Abstract: Disclosed is a tablet, granule or fine granule wherein the release of active ingredient is controlled, comprising: a core particle containing an imidazole derivative of formula (I') where the substituents are as described in the specification; a pH-dependently soluble release-controlled coating-layer which comprises two or more kinds of polymeric substances having different release properties which is dissolved in the pH range of 6.0 to 7.5, selected from the group consisting of hydroxypropylmethyl cellulose phthalate, cellulose acetate phthalate, carboxymethylethyl cellulose, methyl methacrylate-methacrylic acid copolymer, methacrylic acid-ethyl acrylate copolymer, methacrylic acid-methyl acrylate copolymer, hydroxypropyl cellulose acetate succinate, polyvinyl acetate phthalate and shellac; and said pH-dependently soluble release-controlled coating-layer is comprised of two or more kinds of release-controlled coating-layers in which the outermost release-controlled coating-layer is soluble at higher pH than the inner release-controlled coating-layer. Also disclosed are capsules comprising tablets as described.
Patent NZ-553442-A (NZ)
Title: Urine collection bag with angled valve support
Inventor: STAPLETON RYAN T
Filed: 2007-02-26
Abstract: A urine collection bag with support member that is configured to position a discharge valve and spout in an orientation to prevent spills during drainage when the bag is filled or partially filled is disclosed. The bag has a collapsible fluid reservoir and a support member (10) defining a fluid channel (18) and including a spout having an outlet opening (16). The support member is configured such that the longitudinal axis of the spout defines an acute angle between 15 and 75 degrees with a horizontal axis when the fluid reservoir is empty. The support member is configured to support the discharge valve so that it is more accessible when the fluid reservoir is filled with fluid.
Patent NZ-553592-A (NZ)
Title: Post drivers
Inventor: RUSSELL CRAIG BRENDAN
Filed: 2007-03-01
Abstract: A post or pile driver including primary and secondary structures moveable relative to one another by ram assemblies. A monkey is supported by the secondary structure and by a cable and pulleys such that a mechanical advantage is provided. A shield which articulates relative to the primary structure may also be provided.