baber/WOPTO huggingface dataset:
Patent TW-202237733-A (TW)
Title: Fluororesin film, copper-clad laminate and substrate for circuits
Inventor: KOMORI HIROKAZU
IPC: B32B15/082
Filed: 2022-01-20
Abstract: The present invention enables the achievement of: a fluororesin film which is reduced in defects during lamination, while exhibiting good adhesion to a copper foil; and a copper-clad laminate which uses this fluororesin film. A fluororesin film which is formed from a composition containing fluorine, wherein: if the surface state of one surface or both surfaces thereof is determined by a scanning-type X-ray photoelectron spectrometer (XPS/ESCA) after being subjected to a heat treatment at 180 DEG C for 3 minutes, the oxygen element ratio is 1.35 atomic % or more; and if the film is subjected to a heat treatment at 180 DEG C for 10 minutes and is subsequently cooled to room temperature, the absolute values of respective dimensional change rates in MD and TD before and after the heat treatment are 2% or less.
Patent TW-202233618-A (TW)
Title: Organic EL element material, organic EL element, display device, and illumination device
Inventor: TOKUDA TAKASHI
IPC: C09K11/06
Filed: 2022-02-10
Abstract: This organic EL element material is represented by general formula (1). In general formula (1), any one of X1-X3 is a nitrogen atom, and the others are methine groups. L1 represents a substituted or unsubstituted phenylene group, a substituted or unsubstituted naphthylene group, or a substituted or unsubstituted anthrylene group, and L2 represents a single bond, a substituted or unsubstituted phenylene group, a substituted or unsubstituted naphthylene group, or a substituted or unsubstituted anthrylene group. However, if said groups are to be substituted, the substituent group is an alkyl group or an alkoxy group. "A" represents a phenyl group or a pyridyl group, and n represents 0 or 1. Provided is an organic EL element that has excellent light emission efficiency and fatigue life.
Patent TW-202334979-A (TW)
Inventor: YU CHUN-CHIN
IPC: G16H10/40
Filed: 2022-02-15
Abstract: 一種醫檢數據驗證系統，包含：一檢測儀器，用以對數名受檢人員量測，以分別產生數個檢驗數據；及一數據分析儀器，設定不小於一正常範圍之下限值減去一誤差值的一第一臨界範圍，若超過一百分比的受檢人員，於前後二次的檢驗數據分別落在該第一臨界範圍與一第一誤判範圍，該第一誤判範圍與該下限值相差一誤判值，通知該後一次的檢驗數據落在該第一臨界範圍的受檢人員重驗，以各自產生一重測檢驗報告，若各該重測檢驗報告與相對應的該後一次的檢驗數據皆落在相同的該第一誤判範圍時，將該誤差值設定成該誤判值。
Patent TW-202243097-A (TW)
Inventor: CONG ZHEPENG
IPC: H01L21/683
Filed: 2022-02-17
Abstract: 本揭示案的實施例一般相關於用於熱處理半導體基板的基座。在一個實施例中，基座包括：一內區域，該內區域具有在該內區域的一頂部表面中形成的一圖案，該圖案包括由複數個排氣通道分隔的複數個基板支撐特徵。基座包括一輪緣，該輪緣環繞且耦合至該內區域，其中該內區域相對於該輪緣凹陷以形成一凹陷袋部，該凹陷袋部經配置以接收一基板。基座包括複數個凸塊，該複數個凸塊從該輪緣的一內直徑徑向向內延伸，該複數個凸塊經配置以接觸由該複數個基板支撐特徵支撐的一基板的一外邊緣以用於將該基板放置於該凹陷袋部內。
Patent TW-202243990-A (TW)
Inventor: KAKIGI TOMOYUKI
IPC: C08K3/38
Filed: 2022-02-24
Abstract: 本發明之目的在於提供一種六方晶氮化硼粉末，由該粉末可獲得焊料耐熱性優異之樹脂組成物。
 
     本發明可藉由一種六方晶氮化硼粉末來提高樹脂組成物之焊料耐熱性，該六方晶氮化硼粉末的以水作為吸附種而測定出的BET比表面積(S W )、與以氮作為吸附種而測定出的BET比表面積(S N )之比(S W /S N )為0.07以下。又，本發明可藉由一種六方晶氮化硼粉末之製造方法而獲得能提高樹脂組成物之焊料耐熱性的六方晶氮化硼粉末，該六方晶氮化硼粉末之製造方法係包含下列步驟：使硼溶析量為60ppm以下之粗六方晶氮化硼粉末在露點溫度-85℃以下之氮環境下且在1300℃以上、2200℃以下進行加熱處理。
Patent TW-202236478-A (TW)
Inventor: HUANG YEN-HAO
IPC: F16K17/20
Filed: 2022-03-01
Abstract: 本發明實施例的一種接合工具包括氣體供應管線，氣體供應管線可直接在和氣體供應罐相關聯的閥門與處理腔室之間延伸，使得氣體供應管線在無任何中間閥門或其他類型的結構的情況下不間斷，否則中間閥門或其他類型的結構可能會導致在處理腔室與和氣體供應罐相關聯的閥門之間的氣體供應管線中的壓力累積。氣體供應管線中的壓力可維持在處理腔室中的壓力或接近處理腔室中的壓力，使得經由氣體供應管線被提供到處理腔室的氣體不會導致處理腔室中的壓力不平衡，否則壓力不平衡可能會導致將在處理腔室中接合的半導體基底之間的提早接觸或過早接觸。
Patent TW-202237238-A (TW)
Inventor: CHANG SOO-HO
IPC: A63B69/36
Filed: 2022-03-14
Abstract: A spin calculation method for a golf ball moving by being hit, according to an embodiment of the present invention, comprises the steps of: obtaining a first image and a second image which are consecutive images of a golf ball marked with a plurality of markers and moving by being hit; calculating information regarding a reference marker and a plurality of peripheral markers around the reference marker with respect to a plurality of markers on a first ball image corresponding to a golf ball part of the first image; specifying a combination of markers corresponding to the reference marker and the plurality of peripheral markers of the first ball image in a second ball image corresponding to a golf ball part of the second image; and calculating a spin axis and a spin amount by using respective center points of a pair of corresponding markers on the first ball image and the second image.
Patent TW-202310199-A (TW)
Inventor: TSAO CHIH-MING
IPC: H01L21/8249
Filed: 2022-04-08
Abstract: 本發明實施例揭露一種監測一半導體製造設備之方法及一種半導體製造設備。該方法包含透過複數個氣體管線收集一無塵室中之環境空氣，其中該複數個氣體管線之進氣口配置於該無塵室中之複數個取樣位置處。該方法亦包含由連接至該等氣體管線之複數個度量裝置量測該環境空氣之一參數。同時量測該等取樣位置之至少兩者。該方法進一步包含在由該等度量裝置檢測之該參數超出可接受值之一範圍時發出一警告。
Patent TW-202309005-A (TW)
Title: Microbiocidal quinoline/quinoxaline isoquinoline derivatives
Inventor: WEISS MATTHIAS
IPC: A01P3/00
Filed: 2022-04-18
Abstract: Compounds of the formula (I): wherein the substituents are as defined in claim 1, useful as pesticides, especially as fungicides.
Patent TW-202330048-A (TW)
Title: Medical injection system
Inventor: CHANG CHUN-YUN
IPC: A61M5/142
Filed: 2022-04-20
Abstract: A medical injection system is provided. The medical injection system comprises an injection module and the cartridge module coupled to the injection module. The injection module comprises a lead screw movable along an axial line into the cartridge module; a driver sleeve configured to partially accommodate the lead screw and to have a first sleeve end facing a distal end and having sleeve teeth; a dose plate including a first plate end facing the distal end, a second plate end facing a proximal end and having plate teeth corresponding to sleeve teeth, and a side surface located between the first plate end and the second plate end and having a surface tooth; and an indicia tube configured to accommodate the driver sleeve and the dose plate and to have tube concaves near a first tube end facing the distal end. The surface tooth corresponds to one of the tube concaves.
Patent TW-202249467-A (TW)
Title: Selective importing of ue addresses to vrf in 5g networks
Inventor: PATEL KEYUR
IPC: H04L29/06
Filed: 2022-04-22
Abstract: Importing of a UE address into a VRF of perimeter equipment is facilitate by receiving a VPN update from the perimeter equipment including a route target of the perimeter equipment and a gNodeB address. In addition, session information is obtained by intercepting traffic between the UE address and a UPF. The session information including the UE address and address of a gNodeB to which the UE is connected. By matching the gNodeB addresses from the VPN update and the session information, the route target of the perimeter equipment to which the UE is connected may be determined. The UE address may then be imported exclusively into the VRF of the perimeter equipment.
Patent TW-202243627-A (TW)
Title: Window shade and actuating system thereof
Inventor: HUANG CHIEN-FONG
IPC: A47H13/00
Filed: 2022-04-29
Abstract: An actuating system for a window shade includes a rotary axle, a cord winding assembly and a limiting mechanism. The cord winding assembly is coupled to the rotary axle and is connected with a plurality of suspension cords, the rotary axle being rotatable to cause the cord winding assembly to wind and unwind the suspension cords for displacing a movable rail of a window shade. The limiting mechanism includes a latch coupled to one of the suspension cords, the latch being movable between a locking state for preventing rotation of the rotary axle and an unlocking state for rotation of the rotary axle, the limiting mechanism being configured so that tensioning and loosening of the one of the suspension cords causes the latch to switch between the locking state and the unlocking state.
Patent TW-202244378-A (TW)
Inventor: OKUMURA KATSUYUKI
IPC: H03K17/96
Filed: 2022-05-10
Abstract: 門開閉裝置2，具備：上軌道40，在門寬方向上導引著拉門門片30的上端側；驅動機構50，使該拉門門片在門寬方向上滑動；接收部34，連接至控制該驅動機構的控制部55；操作部16，接受用以使該拉門門片滑動的操作；以及傳送部19，設置成在門厚方向位於其中一側，並將該操作部的操作訊號無線傳送至該接收部；在該上軌道，設置固持部45，固持該接收部，而在該上軌道的門厚方向兩側的任一側，皆可選擇性地安裝該接收部。
Patent TW-202307006-A (TW)
Title: Methods of treating cancer with an anti-cd39 antibody and pembrolizumab
Inventor: O'NEILL ALISON
IPC: C07K16/40
Filed: 2022-06-02
Abstract: The invention provides methods and uses of treating cancer with and IgG4 anti-CD39_229p antibody in combination with pembrolizumab, wherein the IgG4 anti-CD39_229p antibody is provided at particular doses and dosages.
Patent TW-202307583-A (TW)
Inventor: HARTJES JOACHIM
IPC: G03F7/20
Filed: 2022-06-10
Abstract: 本發明揭示一種用於EUV微影的光學配置，其包含：一殼體（30）；至少一配置在該殼體（30）的該內部（31）之至少一光學元件；以及至少一氣體結合之構件（32），其具有含一氣體結合材料的至少一表面（33a、33b），用於結合該內部（31）存在的氣態污染物質。該氣體結合之構件（32）經由可從該殼體（30）的外面（30a）斷開之連接（34）而固定到該殼體（30），以從該殼體（30）移除該氣體結合之構件（32）。本發明亦關於一種重建該上述光學配置的至少一氣體結合之構件（32）之方法，其包含：將該氣體結合之構件（32）與該殼體（30）斷開（34）、從該光學配置中移除該氣體結合之構件（32）、以及藉由加熱具有該氣體結合材料的該表面（33a、33b）重建該氣體結合材料。
Patent TW-202310889-A (TW)
Title: Heart pump assembly with a blood inlet configured to increase blood flow
Inventor: SCOTT C CORBETT
IPC: A61M60/165
Filed: 2022-06-29
Abstract: A heart pump assembly having a blood inlet configured to increase blood flow into the heart pump assembly is disclosed herein. The heart pump assembly includes a motor housing, a cannula connected to the motor housing, and a blood inlet connected to the cannula. The blood inlet has a distal body portion, a proximal body portion defining an inlet conduit therewithin, and a plurality of cage openings defined and positioned between the distal and proximal body portions. The inlet conduit has one of a tapered portion, a frustum-shaped portion, or both a tapered portion and a frustum-shaped portion and is adapted to reduce flow turbulence at the blood inlet and increase the blood flow into the heart pump.
Patent TW-202315233-A (TW)
Title: electrical connector
Inventor: WADA HIROSHI
IPC: H01R13/40
Filed: 2022-08-08
Abstract: Provided is a receptacle connector, wherein an electrically conductive contact (11) is a linear member having a uniform width in the plate thickness direction, and extends while bending in an orthogonal plane that is orthogonal to the plate thickness direction. The electrically conductive contact (11) comprises: a contact-touching portion (11a) for contacting a plug contact (21) at a first surface (30) including a linear portion extending in the plate thickness direction; a substrate connection portion (11b) connected to a signal electrode (2b) of a substrate (2) at a second surface (31) including a linear portion extending in the plate thickness direction; and a bent portion (11c) having a first end (32) in the longitudinal direction connected to the contact-touching portion (11a) and a second end (33) in the longitudinal direction connected to the substrate connection portion (11b), and having a shape that is bent in the orthogonal plane between the first end (32) and the second end (33). An apex portion (34) of the bent portion (11c) is press-fitted and locked in an insulating housing.
Patent TW-202246495-A (TW)
Title: Recombinant herpes simplex virus and use thereof
Inventor: HUANG CHENG-HAO
IPC: A61K35/76
Filed: 2018-03-01
Abstract: The invention relates to the field of virology and tumor therapy. In particular, the present invention provides a recombinant herpes simplex virus (HSV) capable of specifically replicating at a high level in a tumor cell and effectively killing the tumor cell, but replicating at low levels in normal cells, thereby the recombinant herpes simplex virus of the present invention not only has high lethality against tumor cells, but also has significantly decreased side effects (especially neurotoxicity). Further, the present invention relates to a viral vector constructed based on the recombinant herpes simplex virus, a pharmaceutical composition comprising the recombinant herpes simplex virus or the viral vector, and the use of the recombinant herpes simplex virus or the viral vector. The recombinant herpes simplex virus of the present invention can be used to infect and kill tumor cells, and can be used for gene drug delivery into tumor cells for gene therapy.
Patent TW-202327389-A (TW)
Title: 考慮暴露限制的用於實現更高的上行鏈路效能的波束選擇
Inventor: LIN JING
IPC: H04W52/04
Filed: 2022-10-20
Abstract: 符合射頻（RF）暴露限制的波束選擇的技術和裝置。一種可以由無線設備進行的方法，包括以下步驟：經由複數個波束從另一個無線設備接收複數個信號；基於接收的複數個信號量測波束中的每一個的接收信號功率；至少部分地基於RF暴露限制來決定波束中的每一個的傳輸功率限制；至少部分地基於接收信號功率和傳輸功率限制來決定波束中的每一個在另一個無線設備處的信號品質的估計；基於波束的信號品質的估計來選擇波束中的一個；及經由選擇的波束來傳輸信號。
Patent TW-202335015-A (TW)
Title: Ion source and ion implantation system
Inventor: BECKER KLAUS
IPC: H01J37/08
Filed: 2022-11-08
Abstract: A Bernas ion source having a shield and an ion implantation system are disclosed. The shield is disposed between the distal portion of the filament and the first end of the chamber and serves to confine the plasma to the region between the shield and the second end of the chamber. The shield may be electrically connected to the negative leg of the filament so as to be the most negatively biased component in the chamber. In other embodiments, the shield may be electrically floating. In this embodiment, the shield may self-bias. The shield is typically made of a refractory metal. The use of the shield may reduce back heating of the filament by the plasma and reduce the possibility for thermal runaway. This may allow denser plasmas to be generated within the chamber.
Patent TW-202336536-A (TW)
Inventor: TSAI TSUNG-CHAN
IPC: G03F7/20
Filed: 2022-11-14
Abstract: 本發明提供一種度量衡裝置，其包括：一探測裝置，其經組態以在與一氣體放電腔室之一增益介質流體連通並曝露於一或多個塵粒子的一光學元件附近產生一探測；一偵測裝置，其經組態以偵測該探測與一或多個塵粒子之間的一相互作用，並基於該偵測到之相互作用產生一輸出信號；及一處理裝置，其經組態以接收該輸出信號並估計該一或多個塵粒子之一性質。
Patent TW-202323064-A (TW)
Title: Multi-application module, multi-application device, and working method for a multi-application device
Inventor: MIEDERER MATTHIAS
IPC: B41F16/00
Filed: 2022-11-28
Abstract: The invention relates to a multi-application module (1), a multi-application device (2), and a working method for a multi-application device (2). The multi-application module (1) for printing a substrate (6) or a transfer product (7) comprises a printing unit (8) and a multifunctional element (9), wherein a printing gap (10) is formed between the printing unit (8) and the multifunctional element (9), the multifunctional element (9) has a first multifunctional roller (91) and/or at least one second multifunctional roller (92) and/or a printing table (13), and the printing unit (8) is designed such that the printing unit can print along two running directions in the printing gap (10).
Patent TW-202330733-A (TW)
Title: resin composition
Inventor: YORISUE TOMOHIRO
IPC: C08G73/10
Filed: 2021-05-28
Abstract: Provided is a resin composition that includes a polyimide precursor and/or a polyimide resin and that satisfies (A) or (B) below: (A) A polyimide structural unit includes a divalent organic group P5 and a tetravalent organic group P6, P5 or P6 includes a structural unit derived from a silicon-containing compound represented by formula (10), and the resin composition contains 25 mass% or less of silicon-containing compounds in terms of the total mass of resin; (B) a resin structural unit includes a divalent organic group P1 and a tetravalent organic group P2, P1 includes a structural unit derived from a compound represented by formula (3), and P1 or P2 includes a structural unit derived from a silicon-containing compound represented by formula (5). [In the formulas, each symbol is as defined in the specification.].
Patent UA-37754-A (UA)
Filed: 2000-04-11
Abstract: The invention relates to medicinene, stomatology and may be used for filling of pulpless teeth. The use of this method at the application of V generation adhesive systems, which provide the method for total picking of hard tooth tissues, allows to increase adhesive force by 1.6 times and decrease regional permeability by 1.5 times between the composite materials and hard tissue of pulpless teeth in comparison with the pulpless teeth, reconstruction of which is carried out according to the prototype, especially in a remote term.
Patent UA-44561-A (UA)
Inventor: KRAMARENKO YURII PETROVYCH
Filed: 2001-05-23
Abstract: The proposed method for isolation of biosynthesis products from cultural liquid involves extraction and ultrafiltration in a single ultrafiltration unit with an anisotropic membrane. According to the method, the cultural liquid and extragent flows are supplied, in the opposite directions, into the ultrafiltration unit, on different sides of the unit membrane made of hydrophilic polymer, with equal pressures in both the flows. Then the following operations are carried out: extracting amino acid or another biosynthesis product using an extragent organic solution; reextracting the extract by passing gaseous reextragent through the extract with the subsequent isolation of crystalline amino acid, the salts thereof, or another biosynthesis product using a separation, filtration or centrifugation process; washing the resulting product with organic solvent and drying the finished product.
Patent UA-44642-A (UA)
Inventor: SHEVCHUK VIKTOR IVANOVYCH
Filed: 2001-07-06
Abstract: The device for fixing of prosthesis contains the frame with the cartridge wrapping the shin stump, the knee-guard, and the belts. The semispherical knee-guard is all-leathered with the belt at the top. The belt is equipped with the rubber ring.
Patent UA-47197-A (UA)
Inventor: TKACHENKO IRYNA MYKHAILIVNA
Filed: 2001-08-30
Abstract: The technique for preparing the unit-cast splint comprises applying the band of the modeling wax onto prepared dental surfaces, modeling the splint within the oral cavity, insertion of the intracanal pin into the previously prepared bed, and manufacturing of the unit-cast splint. The intracanal pin is made from the standard metalic blank set through the band of the modeling wax into the previously prepared bed within the dental tissues.
Patent UA-53261-A (UA)
Title: Two-stroke internal combustion engine
Inventor: MARCHENKO ANDRII PETROVYCH
Filed: 2002-04-16
Abstract: A two-stroke internal combustion engine with spark ignition and crank-chamber blowing with an installed on the case of it cylinder with a piston, piston rings and a piston pin; inside the case there are installed crankshaft, connecting rod, this is in a movable way connected in the upper head to the piston pin, and in the lower head to the crank pin of the crankshaft. As upper and lower heads of the connecting rod there are installed rigidly connected to the rod of the connecting rod closed ball bearings with permanent grease. At that, the last ones are installed in such a way that the area of the connection of those to the rod of the con-rod is made as a surrounding arc of a circle, with the radius of curvature equal to the radius R1 of the outer ring of the upper bearing and R2 of the outer ring of the lower bearing; length of the arc is at that equal to not less than ¼ of the length of the circle of the outer ring of the bearing. Width of the area of connection of the rod of the con-rod with the bearing corresponds to the width of the ring of the bearing; at that the inner diameter of the upper bearing corresponds to the diameter of the piston pin, and the inner diameter of the lower bearing corresponds to the diameter of the diameter of the crank pin; pins are at that installed with tension.
Patent UA-54353-A (UA)
Title: Method for communicating commercial and advertising information
Inventor: MAKSYMOV ANDRII OLEHOVYCH
Filed: 2002-09-17
Abstract: The proposed method for communicating commercial and advertising information consists in representing information of the sender in written form, sending the envelope with information to the recipient by post, and receiving information from the recipient in the same envelope. Within the address area of the envelope, the address is specified that is required for sending the envelope in reverse direction, that is, from the recipient of the initial information to the sender thereof.
Patent UA-57405-A (UA)
Title: Bicycle generator
Filed: 2002-09-27
Abstract: A bicycle generator contains a casing with a winding and a magnetic circuit in which is hinged a magnetic rotor with axis and a driven roller. The-driven roller has holes in which are located balls of ball bearing and axis of magnetic rotor is connected with its internal ring.
Patent UA-60830-A (UA)
Title: Method for treating dysuric syndrome in men
Inventor: ROSSIKHIN VASYL VIACHESLAVOVYCH
Filed: 2003-03-03
Abstract: The method for treating the dysuric syndrome in men provides for the use of non-steroid anti-inflammatory drug. Diclofenac sodium is used in the form of the rectal suppositories (100 mg). In addition the selective-1A adrenolytic Tamsulosin is used at a dose 0.4 mg for 6-7 days.
Patent RS-20050063-A (RS)
Title: Pyrrolidine derivatives as tryptase inhibitors
Inventor: MARTIN THOMAS
IPC: A61P17/00
Filed: 2003-07-24
Abstract: Compounds of a certain formula 1 in which M, B1, B2, R2, K1 and K2 have the meanings indicated in the description are novel effective tryptase inhibitors.
Patent DO-P2009000269-A (DO)
Title: Anticuerpos humanizados contra el globulomero ab(20-42) y sus usos
Inventor: HINTON PAUL R
Filed: 2009-11-27
Abstract: Proteínas de unión, y en particular, anticuerpos humanizados que pueden usarse, por ejemplo, en el diagnóstico, el tratamiento y la prevención de la enfermedad de Alzheimer y condiciones relacionadas.
Patent DO-P2010000073-A (DO)
Title: Un metodo para comprimir combustible gaseoso para el suministro de combustible a un vehiculo y dispositivo para su implementacion
Inventor: SAFRONOVS ALEKSEJS
Filed: 2010-03-05
Abstract: La presente invención se refiere a una preparación de gas natural seguida de la transferencia del gas bajo presión al tanque de combustible del vehiculo 22. El objeto de la presente invención es proveer un dispositivo de llenado de gas individual operado desde la red domiciliaria de gas natural. Conforme a la presente invención se provee un metodo para comprimir gas para suministrar combustible al vehiculo 22 mediante la transferencia alterna de gas 29 en dos recipientes de compresión dispuestos verticalmente 1, 2, su compresión y su paso a presión a recipientes de alta presión mediante el Ilenado de los recipientes de compresión 1, 2 con fluido de trabajo 30 bajo presión por medio de una bomba hidraulica 5, la novedad del metodo de la invención radica en que cada ciclo de compresión de gas y salida a presión del gas 29 de los recipientes de compresión 1, 2 se efectua hasta que dichos recipientes estan totalmente llenos con el fluido de trabajo 30 contenido en los recipientes de compresión 1,2 y alternativamente se saca a presión de un recipients de compresión a otro. Los recipientes de compresión 1, 2 estan provistos de un dispositivo de cierre 3 integrado con las senales de los sensores de nivel de fluido 4 de llenado completo de los recipientes de compresión 1,2 con el fluido de trabajo 30 y montado en los cuellos de los recipientes de compresión 1,2.
Patent DO-P2016000191-A (DO)
Title: COMPUESTOS DERIVADOS DE ESPIRO 1,2-IMIDAZOL Y SU USO COMO INHIBIDORES DE beta-SECRETASA (BACE)
Inventor: RAKOS LASZLO
IPC: C07D491/20
Filed: 2016-07-25
Abstract: LA PRESENTE INVENCIÓN SE REFIERE A COMPUESTOS DE FÓRMULA (I) DERIVADOS DE ESPIRO 1,2-IMIDAZOL Y SUS COMPOSICIONES FARMACÉUTICAS. UN EJEMPLO DE ESTOS COMPUESTOS ES EL COMPUESTO DE FÓRMULA ASIMISMO, LA PRESENTE INVENCIÓN SE REFIERE AL USO DE ESTOS COMPUESTOS COMO INHIBIDORES DE BETA-SECRETASA (BACE) PARA EL TRATAMIENTO Y/O LA PREVENCIÓN DE PATOLOGÍAS RELACIONADAS CON Aß, COMO SÍNDROME DE DOWN, ANGIOPATÍA ß-AMILOIDE COMO, A MODO NO TAXATIVO, ANGIOPATÍA AMILOIDE CEREBRAL O HEMORRAGIA CEREBRAL HEREDITARIA, TRASTORNOS ASOCIADOS CON EL DETERIORO COGNITIVO COMO, A MODO NO TAXATIVO, MCI ("DETERIORO COGNITIVO LEVE"), MAL DE ALZHEIMER, PÉRDIDA DE MEMORIA, SÍNTOMAS DE DÉFICIT DE ATENCIÓN ASOCIADOS CON MAL DE ALZHEIMER, NEURODEGENERACIÓN ASOCIADA CON ENFERMEDADES COMO MAL DE ALZHEIMER O DEMENCIA, INCLUIDA DEMENCIA DE ORIGEN VASCULAR Y DEGENERATIVO MIXTO, DEMENCIA PRESENIL, DEMENCIA SENIL Y DEMENCIA ASOCIADA CON MAL DE PARKINSON, PARÁLISIS SUPRANUCLEAR PROGRESIVA O DEGENERACIÓN CORTICOBASAL.