baber/WOPTO huggingface dataset:
Patent AU-2019282671-A1 (AU)
Title: Transgenic animal for producing diversified antibodies that have the same light chain i
Inventor: LEIGHTON PHILIP A
IPC: C12N15/85
Filed: 2019-06-05
Abstract: This disclosure provides, among other things, strategies for minimizing antibody diversification in a transgenic animal that uses gene conversion for antibody diversification. In some embodiments, the animal may comprise a genome comprising an endogenous immunoglobulin light chain locus comprising: (a) a functional immunoglobulin light chain gene comprising a nucleic acid encoding a light chain variable region; and (b) a plurality of pseudogenes that are operably linked to the functional immunoglobulin light chain gene and that donate, by gene conversion, nucleotide sequence to the nucleic acid encoding a light chain variable region, wherein the pseudogenes are upstream or downstream of the functional immunoglobulin light chain gene and encode the same amino acid sequence as the light chain variable region of the functional immunoglobulin light chain gene of (a). In other embodiments, the locus may have a tandem array of coding sequences for the light chain.
Patent AU-2019287163-A1 (AU)
Title: Nucleic acid amplification method
Inventor: HOGERS RENÉ CORNELIS JOSEPHUS
IPC: C12Q1/6834
Filed: 2019-06-12
Abstract: The invention concerns a method for the production of oligonucleotides. The method of the invention uses a combination of amplification, restriction and affinity purification to produce high quality oligonucleotides. The invention further pertains to a nucleic acid precursor for use in the method of the invention, a solid support comprising said nucleic acid precursor and a kit for use in the method of the invention.
Patent AU-2019310451-A1 (AU)
Title: System and method for measuring a surface in contoured glass sheets
Inventor: ADDINGTON JASON C
IPC: G01N21/17
Filed: 2019-07-24
Abstract: An optical inspection system is provided for an ultraviolet laser and associated optics forming a planar laser sheet directed to a glass sheet. The planar laser sheet intersects a surface of the glass sheet thereby causing the surface of the glass sheet to fluoresce and form a visible wavelength line on the surface. A camera has an image sensor for detecting the visible wavelength line. A control system is configured to receive image data indicative of the visible wavelength line, analyze and triangulate the data to determine a series of coordinates associated with the line, and create a three-dimensional map of the surface of the glass sheet as a function of the series of coordinates. Methods for using an optical inspection system, for gauging a surface using an optical inspection system, and for providing optical reflectance information for a surface using an optical inspection system are also provided.
Patent AU-2019311445-A1 (AU)
Title: Geoid measurement method, geoid measurement apparatus, geoid estimation device, and geoid calculation data collection device
Inventor: KOZUMA MIKIO
IPC: G01C15/00
Filed: 2019-06-04
Abstract: The present invention enables easy measurement of a change in geoid height. This geoid measurement method involves performing an inertial measurement data acquisition step, a contrast data acquisition step, a state variable estimation step, and a geoid calculation step. The inertial measurement data acquisition step is for acquiring, on the basis of outputs of an inertial measurement unit having a triaxial gyro and a triaxial acceleration meter that are to be mounted to a mobile body, data pertaining to velocity, position, and attitude angle as inertia-derived data. The contrast data acquisition step is for acquiring, from a unit other than the inertial measurement unit, velocity-related data as contrast data. The state variable estimation step is for estimating, using the inertia-derived data and the contrast data, a state variable containing a plumb line deviation by applying a Kalman filter in which plumb line deviation is included in the state variable. The geoid calculation step is for determining, on the basis of an estimated plumb line deviation, a change in geoid height at a position determined by said estimation.
Patent AU-2019315718-A1 (AU)
Title: Crystalline forms of N1-(1-cyanocycloproply)-N2-((1s)-1-{4'-((1r-2,2-difluoro-1-hydroxyethyl)biphenyl-4-yl}-2,2,2-trifluoroethyl)-4-fluoro-L-leucinamide
Inventor: JIN XIAOLING
IPC: C07C255/46
Filed: 2019-08-01
Abstract: The present disclosure encompasses crystalline forms of N
Patent AU-2019321434-A1 (AU)
Title: Pyrrolo - dipyridine compounds
Inventor: ELLIES DEBRA
IPC: A61K31/5377
Filed: 2019-08-13
Abstract: In one aspect, the invention provides compounds of Formula I, Formula Ia, Formula Ib, Formula Ic, and Formula Id and salts, hydrates and isomers thereof. In another aspect, the invention provides a method of promoting bone formation in a subject in need thereof by administering to the subject a therapeutically effective amount of a compound of Formula I, Formula Ia, Formula Ib, Formula Ic, or Formula Id. The present invention also provides orthopedic and periodontal devices, as well as methods for the treatment of renal disease, diabetes bone loss, and cancer, using a compound of Formula I, Formula Ia, Formula Ib, Formula Ic, or Formula Id.
Patent AU-2019336894-A1 (AU)
Title: Method and device for coding/decoding image using intra prediction
Inventor: KIM KI BAEK
IPC: H04N19/186
Filed: 2019-09-06
Abstract: A method and a device for encoding/decoding an image according to the present invention may determine a reference region for intra prediction of a current block, derive an intra prediction mode of the current block on the basis of a predetermined MPM candidate group, and perform intra prediction on the current block on the basis of the reference region and the intra prediction mode.
Patent AU-2019351274-A1 (AU)
Title: Treatment methods
Inventor: FLECHTNER JESSICA BAKER
IPC: A61K39/00
Filed: 2019-09-27
Abstract: Methods and compositions for identifying tumor antigens of human lymphocytes, and for treating subjects having cancer, are provided herein.
Patent AU-2019351568-A1 (AU)
Title: PV device having improved overall efficiency
Inventor: FLEISCHER MAXIMILIAN
IPC: H02S50/10
Filed: 2019-08-28
Abstract: The invention relates to a photovoltaic device having a perovskite PV cell and in particular to the efficiency of such a device. According to the invention, the PV device operates, for example during start-up, initially in a bias-voltage operating mode, in which a bias voltage is applied to the perovskite PV cell of the PV device. The bias voltage or the energy needed for same can advantageously be drawn from the power electronics associated with the perovskite PV cell.
Patent AU-2019352938-A1 (AU)
Title: Nutrition-based support for the body's own wound healing processes
Inventor: LINDENSCHMIDT CATHRIN
IPC: A61K36/02
Filed: 2019-09-26
Abstract: The invention relates to the use of a preparation for nutrition-based support for the body's own wound healing processes on a local and systemic level via oral administering of the preparation, which contains, as a base preparation per gram, a conventional mixture of vitamins and nutrients which is in alignment with the nutritional recommendations for good health (i.e. the following substances [a-f], see Commission Directive 2008/100/EG, see Official Journal of the European Union, L285, pages 9 to 12) a. 330 - 385 μg Vitamin B1, b. 420 - 490 μg Vitamin B2, c. 4.8 - 5.6 mg Vitamin B3, d. 1.8 - 2.1 mg Vitamin B5, e. 420 - 490 μg Vitamin B6, f. 15 - 18 μg Vitamin H, and increased amounts (relative to the recommendations) of the following substances [g-k] per gram of base preparation: g. 80 - 390 μg Vitamin B9, h. 1.0 - 4.9 μg Vitamin B12, i. 32 - 156 mg Vitamin C, j. 150 - 731 mg Magnesium and k. 4 - 20 mg Zinc.
Patent AU-2019368545-A1 (AU)
Title: Machine operational state and material movement tracking
Inventor: MEIER IAN ROBERT
IPC: G01C21/16
Filed: 2019-10-24
Abstract: An apparatus, a system and a method indirectly detect the operational state of a machine among a plurality of operational states and track the movement of a material through a plurality of machines.
Patent AU-2019383017-A1 (AU)
Title: Safe and effective method of treating psoriasis with anti-IL-23 specific antibody
Inventor: ANGSANA JULIANTY
IPC: C07K16/24
Filed: 2019-11-19
Abstract: A method of treating psoriasis in a patient by administering an IL-23 specific antibody, e.g., guselkumab, in a clinically proven safe and clinically proven effective amount and the patient achieves PASI90, PASI100 or IGA 0 or 1 score as measured 16, 24, 32, 40 and 48 weeks after initial treatment and the patient achieves higher efficacy than a patient treated with the secukinumab antibody.
Patent AU-2019387317-A1 (AU)
Title: Graphene-oxide grafted pbo (zylon®) fibers; method for production and applications to airship hulls and lighter than air vehicles
Inventor: VESTERGAARD FRANDSEN MIKKEL
IPC: B64B1/58
Filed: 2019-11-25
Abstract: In a method for producing a PBO fiber with increased resistance against UV-caused degradation, a coating is provided on the PBO fibers, wherein the coating comprises graphene oxide cross-linked by polymerization with glutaraldehyde and resorcinol. The fibers are useful for lighter than air vehicles.
Patent AU-2019389001-A1 (AU)
Title: Histotripsy systems and methods
Inventor: CANNATA JONATHAN M
IPC: A61B90/00
Filed: 2019-11-27
Abstract: A histotripsy therapy system configured for the treatment of tissue is provided, which may include any number of features. Provided herein are systems and methods that provide efficacious non-invasive and minimally invasive therapeutic, diagnostic and research procedures. In particular, provided herein are optimized systems and methods that provide targeted, efficacious histotripsy in a variety of different regions and under a variety of different conditions without causing undesired tissue damage to intervening/non-target tissues or structures.
Patent AU-2019399813-A1 (AU)
Title: Intelligent pig group rearing weighing method and apparatus, electronic device and storage medium
Inventor: Ju Tiezhu
IPC: G01G17/08
Filed: 2019-12-10
Abstract: Disclosed are an intelligent pig group rearing weighing method and apparatus, an electronic device and a storage medium. The weighing method comprises: S1, acquiring image information of a pig farm group rearing fence on which to perform intelligent group rearing weighing (101); S2, acquiring image information of each pig within the group rearing fence according to the image information of the group rearing fence (102); and S3, according to the image information of each pig within the group rearing fence, using a preset weight measurement model to acquire weight information of each pig within the group rearing fence, wherein the preset weight measurement model is obtained after training based on image sample input data and weight sample result data of pigs within the group rearing fence (103). According to the intelligent pig group rearing weighing method, the problem of the stress reaction caused by a pig being driven to be weighed on a common weighbridge in the existing pig rearing process can be effectively solved.
Patent AU-2019426739-A1 (AU)
Title: Process for recovering non-ferrous precious metals by pelletisation and calcination of leaching activated carbon powder
Inventor: GRAC YVAN
IPC: C22B11/02
Filed: 2019-01-31
Abstract: The invention relates to a process for recovering precious metals, in particular gold, from activated carbon powder used in a cyanide leaching process for extracting metal, said process comprising the following steps: - an activated carbon powder containing residues of precious metals is mixed with at least one combustible component and water in order to form a mixture based on activated carbon powder loaded with metal, - the mixture is compressed in a compression machine in order to form granules, - the granules are subsequently calcinated in an oven under controlled combustion conditions, particularly at a temperature between 500 and 800°C and for a time between 60 and 120 minutes so as to produce slag and cinders which are mixed in order to form a concentrate, the carbon ratio of which is less than or equal to 1% by weight.
Patent AU-2019440085-A1 (AU)
Title: Systems and methods for slot offset information management
Inventor: MA XIAOYING
IPC: H04W72/04
Filed: 2019-04-02
Abstract: This disclosure relates generally to wireless communications and, more particularly, to systems and methods for communication of slot offset information prior to communicating downlink control information. In one embodiment, a method performed by a communication node includes: determining slot offset indication information that classifies a slot offset information set as either a first kind or a second kind based on at least one of: high-layer configuration signaling and predefined information, and sending the slot offset indication information to a communication device.
Patent AU-2019464927-A1 (AU)
Title: System for displaying information to a user
Inventor: KREYSING MORITZ
IPC: G09G3/34
Filed: 2019-09-06
Abstract: The invention relates to a system for displaying information, comprising: an emission device arranged to emit light so as to display information to a user, the emission device being adapted to emit the light in a pulsed manner so that the intensity of the light varies between a high value and a low value, a selective viewing device comprising a panel, the panel being adapted so that the user can view the light which is emitted by the emission device through that panel so as to visually perceive the information being displayed, the panel having a variable transparency which can be varied between a state of high transparency and a state of low transparency, the system being adapted to synchronize the emission device and the selective viewing device so that the states of the emission device emitting light at a high-intensity value and the states of the panel of the selective viewing device of high transparency overlap in time, the system further comprising a photoelectric conversion means arranged to convert ambient light into electric energy so as to feed the electric energy into the system.
Patent AU-2020200193-A1 (AU)
Title: Platform and method for monitoring an infrastructure for transport vehicles, associated vehicle, transport system and computer program
Inventor: KARAOGUZ CEM
IPC: G08G1/01
Filed: 2020-01-10
Abstract: Platform and method for monitoring an infrastructure for transport vehicles, associated 
vehicle, transport system and computer program 
The invention relates to a platform (14) for supervising an infrastructure for vehicles (12, 12 A), 
a target vehicle (12 A) comprising an obstacle detection module (16) with a predetermined field of 
view and a geolocation module (20) that are embedded, said target vehicle (1 2 A) being able to follow 
a predefined route, the platform (14) comprising: 
- an acquisition module (28) for acquiring, at a current moment, at least one piece of 
information representative of the presence or absence, in a predetermined safety zone, of an 
element (27, GP) outside the target vehicle (1 2 A), and 
- an analysis module (30) for determining whether, at the current moment, the external element 
(27, GP) is in the field of view of the obstacle detection module (16) of the target vehicle (1 2 A), 
and generating and sending a driving setpoint to at least one vehicle on the infrastructure when 
the external element (27, GP) is outside the field of view.  
Figure for abstract: Figure 1
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FIG.1
Patent AU-2020201691-A1 (AU)
Title: Methods of sequencing nucleic acids in mixtures and compositions related thereto
Inventor: EMERICK MARK C
IPC: C12Q1/68
Filed: 2020-03-06
Abstract: Attorney Docket: 09175 PCT This disclosure relates to analyzing the end-to-end sequence and the relative distributions in heterogeneous mixtures of polynucleotides and methods and enabling reagents related thereto. In 5 certain embodiments this method relates to the complete full length sequencing and quantitative profiling of mRNAs present in the transcriptomes of cells or tissues of, but not limited to, higher multicellular organisms that possess interrupted genes subject to complex post-transcriptional RNA processing.
Patent AU-2020207809-A1 (AU)
Title: Systems and methods for intelligent gas source management and/or systems and methods for delivery of therapeutic gas and/or enhanced performance verification for therapeutic gas delivery
Inventor: ACKER JARON M
IPC: A61M16/20
Filed: 2020-07-21
Abstract: SYSTEMS AND METHODS FOR INTELLIGENT GAS SOURCE 
MANAGEMENT AND/OR SYSTEMS AND METHODS FOR DELIVERY 
OF THERAPEUTIC GAS AND/OR ENHANCED PERFORMANCE 
VERIFICATION FOR THERAPEUTIC GAS DELIVERY 
ABSTRACT 
An electronically controlled gas blending device, comprising: a flow control channel in fluid 
communication with a therapeutic gas supply, wherein the flow control channel comprises: at 
least one secondary subsystem flow control valve, wherein the at least one secondary subsystem 
flow control valve is configured to be in communication over a communication path with a 
therapeutic gas delivery system controller; and two or more secondary subsystem flow sensors, 
wherein the two or more secondary subsystem flow sensors are in fluid communication with the 
at least one secondary subsystem flow control valve, and the two or more secondary subsystem 
flow sensors are configured to be in communication over a communication path with the 
therapeutic gas delivery system controller; one or more inlets configured to connect to a gas 
supply; one or more inlet flow sensors in fluid communication with at least one of the one or 
more inlets; a blending junction in fluid communication with the one or more inlet flow sensors, 
and the blending junction is connected to and in fluid communication with the flow control 
channel; and a therapeutic gas delivery system controller configured to be in electrical 
communication with at least one of the at least one secondary subsystem flow control valves and 
the two or more secondary subsystem flow sensors to form a feedback loop, and configured to 
receive a flow value from the one or more inlet flow sensors and calculate a flow rate of the 
therapeutic gas through the at least one secondary subsystem flow sensor to provide an intended 
dose of the therapeutic gas exiting the blending junction, wherein the two or more secondary 
subsystem flow sensors are arranged in parallel along the flow control channel.
Patent AU-2020207862-A1 (AU)
Title: Holder for an acetabular cup implant
Inventor: WOZENCROFT ROBERT
IPC: A61F2/46
Filed: 2020-07-23
Abstract: The present invention is directed to a system comprising a medical instrument (e.g. cup implant, 3) and a 
holding device (2) that interacts with said medical instrument to form a salable cavity within the combined 
5 arrangement of components. An impaction device (1) is also provided, preferably which provides means to 
allow fluid to be expelled from the cavity but which prevents further fluid from entering the cavity.  
FIG. 1
1/18 
7 
2 6 
7 
Figure 2 
3 5 
Figure 1 
10 
13_ 
914 
Figure 3 Figure 4
Patent AU-2020217342-A1 (AU)
Title: Methods of increasing tonic inhibition and treating secondary insomnia
Inventor: DURING MATTHEW
IPC: A61P25/00
Filed: 2020-08-11
Abstract: METHODS OF INCREASING TONIC INHIBITION AND 
TREATING SECONDARY INSOMNIA 
ABSTRACT 
Methods of increasing tonic inhibition in a subject in need thereof, for 
example a subject with Fragile X syndrome or Angelman syndrome are 
disclosed. Methods of treating secondary insonia in a subject with a 
neurodegenerative disease or disorder are also disclosed. The methods can 
include administering the subject an effective amount of 4,5,6,7
tetrahydroisoxazolo(5,4-c)pyridin-3-ol (THIP) or a derivative thereof, or a 
pharmaceutically acceptable salt thereof, increase tonic inhibition in neurons of 
the subject; to increase slow wave sleep (SWS) and/or slow wave activity 
(SWA), normalize sleep architecture, reduce secondary insomnia, increase non
rapid eye movement (NREM) sleep, increase sleep continuity, enhance delta 
activity within NREM, increase or improve total sleep time (TST), increase or 
improve sleep efficiency, reduce total time awake (TAA), reduce number of 
awakenings (NWA), reduce latency to persistent sleep (LPS), or to reduce wake 
after sleep onset (WASO), in the subject, or any combination thereof.
Patent AU-2020217439-A1 (AU)
Title: Electrical stimulator for peripheral stimulation
Inventor: BOGGS II JOSEPH W
IPC: H01R13/639
Filed: 2020-08-14
Abstract: Neurostimulation assemblies, systems, and methods make possible 
the providing of short-term therapy or diagnostic testing by providing electrical 
connections between muscles and/or nerves inside the body and stimulus 
generators and/or recording instruments mounted on the surface of the skin or 
carried outside the body. The assembly affords maximum patient mobility and 
comfort through differentiated components having minimal profiles and 
connected by way of detachable and adjustable connections.
WO 2016/086219 PCT/US2015/062828 
20 50 10 
30 40 
60 70 
FIGURE 1 
22 
20 
40 
30 50 
12 
FIGURE 2A 
1/20
Patent AU-2020227319-A1 (AU)
Title: Methods and agents for assessing T-cell function and predicting response to therapy
Inventor: RAO SUDHA
IPC: G01N33/53
Filed: 2020-02-27
Abstract: This disclosure relates generally to methods and agents for assessing T-cell function and for predicting responses to therapy. More particularly, the present invention relates to methods and agents for detecting different forms of Eomesodermin (EOMES) in T-cells, which are useful for assessing the function of a T-cell, for assessing the immune function of a subject, for predicting the likelihood of response of a cancer patient to therapy including immunotherapy, for stratifying a cancer patient as a likely responder or non-responder to a therapy, and for managing treatment of a cancer patient.
Patent AU-2020227824-A1 (AU)
Title: Modulators of MALAT1 expression
Inventor: FREIER SUSAN M
IPC: C12N15/113
Filed: 2020-02-27
Abstract: The present embodiments provide methods, compounds, and compositions useful for inhibiting MALAT1 expression, which may be useful for treating, preventing, or ameliorating a cancer associated with MALAT1.
Patent AU-2020230228-A1 (AU)
Title: Superconducting circuit structure, superconducting quantum chip and superconducting quantum computer
Inventor: JIN LIJING
IPC: G06F13/14
Filed: 2020-09-07
Abstract: The present application discloses a superconducting circuit structure, a superconducting 
quantum chip, and a superconducting quantum computer, which are related to a field of quantum 
computing. The specific implementation includes: a superconducting circuit structure, including: at 
5 least three computational qubits; a bus qubit connected to the respective computational qubits, 
wherein couplings between two of the computational qubits connected by the bus qubit are equivalent; 
and coupler qubits disposed between the respective computational qubits and the bus qubit, to connect 
the respective computational qubits to the bus qubits, wherein the coupler qubit is configured to 
regulate coupling strength between the computational qubit and the bus qubit. Couplings between 
0 any two computational qubits may be realized, so that an operation of a quantum gate between any 
two computational qubits is achieved, while crosstalk between computational qubits may be 
effectively suppressed.  
(FIG. 3) 
18
computational 
qubit Q 
coupler module 
*...coupler.  
C 0 :qubit: c: C2 
'Busbus C :,Q 
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, FI. 3 4: