baber/WOPTO huggingface dataset:
Patent PT-920430-E (PT)
Inventor: MORRISSEY MICHAEL M
IPC: A61P7/02
Filed: 1997-08-14
Abstract: This invention is directed to purine derivatives of the following formulae:    <IMAGE>  (I)   <IMAGE>  (II)   <IMAGE>  (III)   <IMAGE>  (IV)  wherein Z1 is -O-, -N(R10)- or -CH2O-; Z2 is -O-, -N(R10)- or -OCH2-; R1 and R4 are each independently hydrogen, halo, alkyl, -OR10, -C(O)OR10, -C(O)N(R10)R11, -N(R10)R11, -N(R10)C(O)R10, or -N(H)S(O)2R13; R2 is -C(NH)NH2, -C(NH)N(H)OR10, -C(NH)N(H)C(O)OR13, -C(NH)N(H)C(O)R10, -C(NH)N(H)S(O)2R13, or -C(NH)N(H)C(O)N(H)R10; R3 is halo, alkyl, haloalkyl, haloalkoxy, ureido, cyano, guanidino, -OR10, -C(NH)NH2, -C(NH)N(H)OR10, -C(O)N(R10)R11, -R12-C(O)N(R10)R11, -CH(OH)C(O)N(R10)R11, -N(R10)R11, -R12-N(R10)R11, -C(O)OR10, -R12-C(O)OR10, -N(R10)C(O)R10, (1,2)-tetrahydropyrimidinyl (optionally substituted by alkyl), (1,2)-imidazolyl (optionally substituted by alkyl), or (1,2)-imidazolinyl (optionally substituted by alkyl); R5 is hydrogen, halo, alkyl, cycloalkyl, haloakyl, aryl, aralkyl, alkylthio, hydroxy, mercapto, alkoxy, or -N(R10)R11; and R6 is defined herein. These compounds are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to treat disease-states characterized by thrombotic activity.
Patent PT-899533-E (PT)
Inventor: GATTNAR JOHANN ERNST
IPC: F41A23/20
Filed: 1998-08-25
Abstract: A pivot arm (1) outside the turret hatch (3) is pivotably fitted around a static, vertical axis (5) and on the weapon (9, 9') or on a retainer fitted on it around a movable vertical axis (25). The pivot arm preferably includes two parts (13,15), which are connected with one another by a link (17).A release lever (19) is provided for the link (17), which can be held in a rest position by a spring or similar. It is movable into a release position by a handle (21) fitted to it. By application of only one link the release lever is formed as a pivot lever, which with its one end is pivotably fitted on the part (13) of the pivot arm (11) which is located on the static axis (5).
Patent PT-1007115-E (PT)
Title: Medication delivery apparatus
Inventor: BYDLON ROLAND JOSEPH
IPC: A61M5/20
Filed: 1998-06-04
Abstract: A medication delivery apparatus including a housing, a container of medication mounted to the housing, an outlet such as an injection needle, and a drive assembly adapted to force medication from the container and through the outlet upon movement of an actuator. The housing periphery includes a projecting abutment for digit engagement which is ergonomically designed for abutting contact by a first digit of a hand of a user when the housing is grasped within the user's hand such that a second digit of the hand of the user may operate the actuator. When the actuator is moved axially, this abutting contact of the first digit with the abutment permits application of an axial force by the first digit on the abutment in a direction generally opposite to an axial force applied to move the actuator. As this user applied force on the abutment reduces the amount of frictional force required to be applied by the user on the apparatus housing to counteract the force applied to the actuator during medication delivery, the apparatus housing may be gripped less tightly during use. The housing also is provided with a gripping layer on its periphery formed of a soft touch material.
Patent PT-990807-E (PT)
Inventor: PORCHER JEAN-MICHEL GEORGES MA
IPC: F23N1/08
Filed: 1999-09-30
Abstract: The gas valve cover has a sleeve (30) fitting onto a stub (31) and having four side faces (32,33,36,37), two of which have a groove (50,51) corresponding two recesses (55,56) in the stub. An elastic wire (40) on the sleeve has two branches (42,43) to engage the grooves after assembly.
Patent PT-1070285-E (PT)
Inventor: STERLING HANS RUDOLF
IPC: G06F3/0354
Filed: 1999-04-06
Abstract: A computer system comprises a keyboard ( 11 ), a display screen ( 13 ), a first pair of position-sensing electrodes ( 18.1, 18.2 ), a second pair of position-sensing electrodes ( 20.1, 20.2 ), a signal injection electrode ( 22 ), and an oscillator ( 27 ). The oscillator injects a signal via the signal injection electrode and the operator's left hand (L) into the operator's body, and this creates a field around the operator's right hand (R). The position-sensing electrodes are arranged underneath the keyboard and sense the strength of the field. This enables the position of the operator's right hand (R) in an X-Y plane above the keyboard to be determined. To this end the position-sensitive electrodes are connected via synchronous detectors ( 34, 44 ) and an analogue-to-digital converter ( 36 ) to a microprocessor ( 46 ), which operates to control the position of a cursor on the display screen.
Patent PT-1094837-E (PT)
Title: Porcine circovirus and parvovirus vaccine
Inventor: MCNEILLY FRANCIS
IPC: A61K39/295
Filed: 1999-06-28
Abstract: The invention relates to antigenic preparations and vaccines directed against the porcine multisystemic wasting syndrome (PMWS), comprising at least one porcine circovirus antigen, preferably type II, and at least one porcine parvovirus antigen.
Patent PT-1140104-E (PT)
Title: Treatment of alzheimer`s disease by increasing cytidine levels in vivo
Inventor: WATKINS CAROL
IPC: A61K31/235
Filed: 1999-07-30
Abstract: A preparation for use in the prevention and/or treatment of neurological disorders, said preparation comprising (a) uridine or a uridine source and (b) choline, a choline precursor, a choline salt or ester, or a mixture thereof.
Patent IE-820199-L (IE)
Title: Dibenzofuran derivatives
IPC: C07D453/02
Filed: 1982-01-29
Abstract: Dibenzofuran derivatives of the formula   <IMAGE>   where R1, R2, R3, X, A, Y, m, n, p and q have the meanings given in the description, and their use for controlling fungi.
Patent IE-38929-L (IE)
Title: Sulphonylbenzamide derivatives
IPC: C07C317/46
Filed: 1974-02-26
Abstract: 1420574 Process for 2,5-disubstituted-benzamides SOC D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DEFRANCE 26 Feb 1974 [1 March 1973] 8665/74 Heading C2C Compounds of general Formula (I) are made by reacting a 2,5-disubstituted benzoyl chloride with lead thiocyanate and thereafter reacting the compound (III) so obtained with H 2 N(CH 2 ) n A (I can, if desired be converted into a salt thereof; A is mono- or di-C 1-5 alkylamino or a heterocyclic saturated ring containing N, O and/or S, B is C 1-5 alkyl or alkenyl, n is 1 or 2 and X is NH 2 , mono- or di-alkylamino, alkenyl or alkyl). A is, e.g. diethylamino or a group of Formula (II) where m is 1 to 3 and R is alkyl, especially a 1-ethyl-2-pyrrolidyl-group.
[GB1420574A]
Patent IE-840528-L (IE)
Title: 1-(2-carbethoxy-4-benzalkylamido phenoxy)-3-amino-2-propanol
IPC: A61K31/00
Filed: 1984-03-05
Abstract: 1. Claims for the Contracting States : BE CH DE FR GB IT LI LU NL SE Compounds characterized in that they respond to formula :  see diagramm : EP0122827,P20,F2  in which : - R and R' may each designate an atom of hydrogen, an atom of halogen, a nitro group or alkyl or alkoxy radicals with C1-C5, branched or not, or a SCH3 or CF3 group ; - R1 represents a lower alkyl radical with 1 to 5 carbon atoms, branched or not ; - R2 represents a lower alkyl radical with 1 to 5 carbon atoms, branched or not ; and - n designates an integer less than 5. 1. Claims for the Contracting State : AT A process for preparing novel compounds responding to formula  see diagramm : EP0122827,P21,F2  in which : - R and R' may each designate an atom of hydrogen, an atom of halogen, a nitro group or alkyl or alkoxy radicals with C1-C5, branched or not, or a SCH3 or CF3 group ; - R1 represents a lower alkyl radical with C1 -C5 , branched or not ; - R2 represents a lower alkyl radical with C1 -C5 , branched or not ; and - n designates an integer less than 5, characterized in that said process comprises the step of reacting a base of formula NH2 -R2 where R2 is as defined hereinabove, on a compound of formula (II) without solvent or in a conventional organic solvent such as alcohols, at a temperature of between 20 degrees C and 150 degrees C, see diagramm : EP0122827,P21,F3  R, R', R1 and n being as defined hereinabove.
Patent IE-820620-L (IE)
Title: Fungicidal compositions
IPC: A01N47/38
Filed: 1982-03-18
Abstract: Composition containing: a-from 20 to 40% of iprodione, b-an oil-in-water emulsion containing 50 to 160% by weight, relative to the iprodione, of an oil of which the hydrophilic/lipophilic balance has a value of 9 to 12, and c-from 0.1 to 2% by weight of an emulsifier of the ethylene oxide/fatty alcohol condensate type. Composition for the protection of plants against fungal diseases.
[US4785013A]
Patent IE-34291-L (IE)
Title: Applying labels or plates to hollow-thermo-plastics bodies
IPC: B29C49/24
Filed: 1970-06-09
Abstract: 1302284 Blow-moulding; labelling E LANGECKER 19 May 1970 [12 June 1969] 24076/70 Heading B5A A weldable or adhesive sheet or film is applied as a label or plate to an article during blowmoulding by holding it tautly across the face of a plunger which face corresponds to the shape of the hollow body, with a gap between the label centre and plunger face and advancing the plunger during blow-moulding so that the label centre is pushed toward the plunger face on contacting the article and wrapped around the article. As shown in Fig. 3, the mould comprises halves 1, 2 and a strip is fed in a guide formed by members 12-14 and plunger 5 advanced by jack 6 to cut a label 15 therefrom against member 14, top and bottom transverse cuts (25, Fig. 1, not shown) having been made in the strip by means (23, 24). The label is held by seating surfaces 11 of the plunger 5 and clamps 16 operated by compression springs 21. Plunger 5 is further advanced, label 15 contacting the expanding parison 4 and being pressed toward the plunger surface (Fig. 4, not shown). The label is wrapped around the article when the plunger is fully advanced. Instead of clamps 16, the seating surfaces 11 may have vacuum passages (27, Fig. 7, not shown). The label may alternatively be cut from a horizontally, transversely moving strip (Fig. 8, not shown) or may be ready cut (Figs. 9-12, not shown).
[GB1302284A]
Patent FI-821453-L (FI)
Inventor: GOTTLIEB KLAUS
IPC: C07C9/08
Filed: 1982-04-27
Abstract: A process for producing isopropyl alcohol and isopropyl tert-butyl ether from a mixture of light hydrocarbons containing propane and butane, comprises: (a) separating from the mixture of light hydrocarbons a propane fraction and a butane fraction containing at least n-butane; (b) isomerizing at least a portion of the n-butane in the butane fraction from step (a) whereby a hydrocarbon mixture containing at least n-butane and isobutane is formed; (c) catalytically dehydrogenating the isobutane in the hydrocarbon mixture from step (b) whereby a hydrocarbon mixture containing at least isobutene is produced; (d) catalytically dehydrogenating the propane in the propane fraction from step (a) whereby a hydrocarbon mixture containing at least propene is produced; (e) reacting the propene in the hydrocarbon mixture from step (d) with water, whereby a mixture containing hydrocarbons and isopropyl alcohol is formed; (f) reacting the isopropyl alcohol from step (e) with at least part of the isobutene in the hydrocarbon mixture from step (c) whereby a mixture containing hydrocarbons and isopropyl tert-butyl ether is formed; (g) recycling the hydrocarbons in the hydrocarbon mixture from step (e) to step (d), respectively; (h) recycling the hydrocarbons in the hydrocarbon mixture from step (f) to step (c); and (i) recovering at least the isopropyl tert-butyl ether.
Patent FI-821497-L (FI)
Inventor: HEIZ ULRICH
IPC: B65G65/00
Filed: 1982-04-29
Abstract: A transfer apparatus wherein the conveyed loads, which need not absolutely possess a square or rectangular cross-sectional area or configuration, are received by or delivered from a transport vehicle, without the load itself having to experience a tilting movement, when it departs, for instance, from a stationary chain conveyor and is taken-over by the chain conveyor of a displacement carriage. The gap between the stationary chain conveyor and the chain conveyor mounted upon the transport vehicle is bridged by the laterally movable displacement carriage. The related chain drive serves for moving the conveyor chains of the chain conveyor and the displacement carriage. An alternately effective brake-locking device controls both movements. With blocked conveyor chains the displacement carriage, depending upon the direction of rotation of the drive motor of the chain drive, moves laterally in one or the other direction until reaching a related lateral stop or impact member. With released conveyor chains and blocked displacement carriage the conveyor chains of the chain conveyor are displaced until the conveyed load can be transferred or received, as the case may be.
Patent FI-831890-L (FI)
Inventor: SKUBALLA WERNER
IPC: C07C69/66
Filed: 1983-05-26
Abstract: Carbacyclin esters of Formula I <CHEM>  wherein  R1 is an unsubstituted or substituted aromatic residue,  R2 is a free or functionally modified hydroxy group, R3 is an alkyl or cycloalkyl group, or an optionally substituted aryl group, or a heterocyclic group,  X is oxygen atom or the group -CH2-,  A is a -CH2-CH2-, trans-CH=CH-, or -C IDENTICAL C-group, W is a free or functionally modified hydroxy-methylene group or a free or functionally modified <CHEM>  wherein the OH-group can be in the  alpha - or  beta -position,  D is the group <CHEM> a straight-chain saturated alkylene group of 1-5 carbon atoms, a branched, saturated or a straight-chain or branched, unsaturated alkylene group of 2-5 carbon atoms, which groups can optionally be substituted by fluorine atoms, E is a direct bond, a -C IDENTICAL C- group, or a -CR4=CR5- group wherein R2 and R5 mean a hydrogen atom or an alkyl group of 1-5 carbon atoms; are useful as blood-pressure-lowering agents, inter alia.
Patent IE-831150-L (IE)
Title: Pipe discharge ramp for underwater pipe laying
IPC: F16L1/225
Filed: 1983-05-17
Abstract: An articulated stinger attachable to a pipelaying vessel and constructed of a plurality of elongated multi-leg segments arranged in end-to-end relationship and interconnected by flexible joints. Each flexible joint is comprised of at least three components: two sockets, each in abutting ends of the multi-leg segments, and a socket-filling member. The stinger may be arranged inclined to the horizontal as in conventional pipelaying practice, or vertically for J-method pipelaying. A resilient element may be carried within the sockets to yieldably restrain relative movement between the socket and the socket-filling member.
[US4472079A]
Patent IE-36759-L (IE)
Title: Pyrrolidine derivatives
IPC: C07C311/29
Filed: 1972-10-12
Abstract: 1353571 Process for N-(1-ethyl-alpha-pyrrolidylmethyl) - 2 - methoxy - 5 - sulphonamidobenzamide FRATMANN AG 29 Sept 1972 [13 June 1972] 44945/72 Heading C2C The invention comprises a process for preparing N-(1-ethyl-α-pyrrolidylmethyl)-2-methoxy-5-sulfonamidobenzamide, by (a) converting an alkyl 2-methoxy-5-sulfonamidobenzoate into the acid hydrazide, (b) converting the acid hydrazide into the acid azide, and (c) reacting the acid azide with 1-ethyl-2-aminomethylpyrrolidine; the hydrochloride of the said benzamide is also prepared.
[GB1353571A]
Patent IE-33625-L (IE)
Title: Device for mounting a prosthesis.
IPC: A61C8/00
Filed: 1969-11-12
Abstract: 1291470 Implantable supports for prostheses AGA AB 12 Nov 1969 [9 Dec 1968] 55297/69 Heading A5R A device for mounting protheses such as false teeth, on skeleton tissue, comprises at least two interconnectable units, i.e. a fixture unit 10 to be permanently implanted in the tissue and a "distance unit" 22, 24 to which the protheses are attached. The outer surface of the fixture unit 10 is provided with a rough and/or porous surface and holes 12 to permit skeleton tissue to attach to the unit when the unit is located in the skeleton. This fixture unit surface may have a screw thread. Two bores 11 and 14 are provided in unit 10, bore 14 being threaded to receive a male thread on the "distance unit". The "distance unit" comprises a sleeve part 22 and fitting bolt part 24 and the latter is provided with a female thread to receive the prothesis. Fixture unit 10 includes a releasable ring 17 provided with a sharp edge 19 at its outer lower side to facilitate grafting to the skeleton. Alternatively an integral flange (35) having an edge (31) may be provided (Fig. 5). A screw 20 is arranged to be temporarily screwed into unit 10 with ring 17 instead of the distance unit, during initial implantation in the skeleton. In an embodiment, a single threaded bore in unit 10 receives a screw (29) which acts on a disk (28) movable to force flanges (27) on the unit 10 outwards, to facilitate bonding to the skeleton. Bolt part 24 of the "distance unit" includes a weakend neck and heat insulating material. The fixture is of plastics material or titanium.
[SE332486B]
Patent IE-33425-L (IE)
Title: Fluid treatment of textile material
IPC: D06B1/02
Filed: 1969-12-02
Abstract: 1294471 Fluid treatment of a web JONATHAN LOGAN Inc 9 Dec 1969 [10 Dec 1968] 60125/69 Heading D1L A textile web F is overfed by feed rolls 17 and 18 onto an endless, moving foraminous felt 21 where it is sprayed from at least below and preforably from above and below the belt by jets of treatment liquid from nozzles 30, the force of the lower jets at least balancing the combined downward force of the upper jets and the weight of the wet and temporarily lifting parts of the web out of engagement with the belt, the web being removed from the belt by extraction rolls 35 and 36. The nozzles are adjustably mounted on pipes 31 which are adjustably mounted in a housing 11 containing said belt. The liquid may be treated by steam heated coils 48 in the base of the housing 11 and may be recirculated from a drain pipe 38 through a filter, surge tank and valves to the pipes 31. Two such belts in series (21A' and 21B', Fig. 4) may be employed, the first belt moving faster than the second. The drive of the belt, feed rolls and extraction rolls may be linked.
[GB1294471A]
Patent IE-901809-L (IE)
Title: N-(Aryloxyalkyl)heteroarylpiperidines and¹-heteroarylpiperazines, a process for their preparation and¹their use as medicaments
IPC: C07D401/04
Filed: 1990-05-18
Abstract: This invention related to compounds of the formula: <CHEM>  wherein  X is -O-, -S-, - @H, or -@-R<2>;  p is 1 or 2; Y is hydrogen, C1 to C6 alkyl, -OH, Cl, F, Br, I, C1 to C6 alkoxy, -CF3, NO2, or -NH2, when p is 1;  Y is C1 to C6 alkoxy when p is 2 and X is -O-; R<2> is selected from the group consisting of lower alkyl, aryl lower alkyl, aryl, cycloalkyl, aroyl, alkanoyl, and phenyl sulfonyl groups;  Z is -CH- or -N-;  n is 2, 3, 4, or 5; R is hydrogen, alkyl, C1 - C6-alkoxy, hydroxyl, carboxyl, Cl, F, Br, I, amino, C1 - C6-mono or-dialryl amino, -NO2, lower alkyl thiol -OCF3, cyano, acylamino, -CF3, trifluoroacetyl, aminocarbonyl, <CHEM>  where  alkyl is lower alkyl;  aryl is phenyl or <CHEM> R1 is hydrogen, lower alkyl, C1 - C6 alkoxy, hydroxy, Cl, F, Br, I, C1 - C6 alkyl amino, -NO2, -CN, -CF3, -OCF3; and  heteroaryl is <CHEM>  where  Q is -O-, -S-, - @H, -CH=N;  R3 is hydrogen, lower alkyl, or acyl; and  m is 1, 2, or 3;  or a pharmaceutically acceptable acid addition salt thereof. The invention relates further to a process for the preparation of the above compounds and their use as medicaments having antipsychotic and/or analgetic activity.
Patent IE-831830-L (IE)
Title: Beta-lactams
IPC: A61P31/04
Filed: 1983-08-03
Abstract: Antibiotic activity is exhibited by beta -lactams having an <IMAGE> substituent (and analogs thereof) in the 1-position and an acylamino substituent in the 3-position.
[US4939253A]
Patent IE-871881-L (IE)
Title: Screw pipe connection
IPC: E21B17/042
Filed: 1987-07-13
Abstract: The invention provides a joint between two tubes comprising a box (16) at one end of one tube and a pin (15) at ne end of the other tube, the pin (15) being provided on its external surface with a threadless zone at its nose (13) serving as a stabbing guide for entry of the pin into the box, a parallel threaded load carrying zone, and an inclined threaded locking and load carrying zone (4); the box (16) being provided on its inner surface with a parallel threaded load carrying zone (9), and an inclined threaded locking and load carrying zone (12), both generally matching and engageable with the corresponding zones of the pin, and an unthreaded stabbing guide zone (5) axially disposed between said parallel load carrying zone (9) and said inclined locking and load carrying zone (12) of the box; the parallel load carrying zone (12) in the box (16) serving as an extension of the stabbing guide provided between the parallel load carrying zone and the inclined locking and load carrying zone for the nose of the pin, and the two threaded zones in the box being so separated that the parallel threaded load carrying zone (9) engages with the corresponding threaded zone (3) on the pin firstly on make-up of the joint.
[EP0254552A1]
Patent IE-781962-L (IE)
Title: Phenyl isothiocyanate derivatives
IPC: C07C325/00
Filed: 1978-10-02
Abstract: NEW MATERIAL:Compounds of formula I (R<1> is alkoxy, hydroxy, amino, alkylamino, diakylamino, arylamino, tetrahydrofurfurylamino, or morpholino; R<2> is alkyl alkoxycarbonyl; R<3> is alkyl alkoxy, dialkylamino, halogen) and their salts. EXAMPLE:3-Methoxycarbonyl-4,5-dimethoxyphenyl isothiocyanate. USE:Fungicide for agriculture and horticultrure. Especially effective against powdert mildew and downy mildew in the gourd family and rice blast disease. PREPARATION:The reaction between a compound of formula II and an inorganic or organic base is conducted in an organic solvent with susequent action of a halogenated alkyl carbonate thereon to form a compound of formula I.
[JP54055550A]
Patent IE-802272-L (IE)
Title: Bis (allylcarbonate) compound synthesis
IPC: C07C69/96
Filed: 1980-11-03
Abstract: Disclosed is a method of synthesizing a polyol (allyl carbonate) by the alkali metal hydroxide catalyzed reaction of allyl alcohol and a polyol chloroformate where a portion of the alkali metal hydroxide is anhydrous.
[US4273726A]
Patent IE-822423-L (IE)
Title: Mandassi root extract
IPC: A61K36/18
Filed: 1982-10-06
Abstract: From the roots of the plant Mandassi (Cyperus articulatus L.) a fraction is extracted which is therapeutically useful, more particularly as an anticonvulsant.
[US4483852A]
Patent NO-801815-L (NO)
Inventor: KUIPER JAN
IPC: C11C3/12
Filed: 1980-06-18
Abstract: Triglyceride oils, which contain besides fatty acids having two double bonds, fatty acids having more than two double bonds, are hydrogenated using palladium, platinum, rhodium and/or iridium as a catalyst, the catalyst being treated with dry ammonia. The hydrogenation is carried out at a temperature of at least 100 DEG  C. The hydrogenation progresses in a particularly selective manner. On using, for instance, soyabean oil, which contains about 55% of linoleic acid and 7% of linolenic acid, the amount of linolenic acid can be reduced to 2%, whereby more than 45% of linoleic acid is retained in the hydrogenated product. In case the catalyst is not treated, said amount is only about 35%.
Patent NO-801853-L (NO)
Inventor: ROSSEY GUY
IPC: A61K31/395
Filed: 1980-06-20
Abstract: Vincaminic acid derivatives of formula (A)    <IMAGE>  (A)  useful in treating cerebral insufficiency, are prepared by reacting 1-ethyl-2,3,4,6,7,12-hexahydroindolo[2,3-a]quinolizine with the 2,4-DNP hydrazone of ethyl or methyl bromopyruvate followed by (i) reduction of the C=N bond and (ii) simultaneous cyclization with removal of the ketone-protecting group in either order.