Patent SG-11201906192S-A (SG)
Title: Methods of treating cancer with anti-pd-1 antibodies
Inventor: JENKINS DAVID
IPC: A61P35/00
Filed: 2018-01-09
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 12 July 2018 (12.07.2018) WIP0 1 PCT Ilium omit Oil Oil mum ono mom oimIE (10) International Publication Number WO 2018/129559 Al (51) International Patent Classification: CO7K 16/28 (2006.01) A61P 35/00 (2006.01) (21) International Application Number: PCT/US2018/013029 (22) International Filing Date: 09 January 2018 (09.01.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/444,336 09 January 2017 (09.01.2017) US 62/477,423 27 March 2017 (27.03.2017) US 62/491,220 27 April 2017 (27.04.2017) US 62/556,386 09 September 2017 (09.09.2017) US (71) Applicant: TESARO, INC. [US/US]; 1000 Winter Street North, Suite 3300, Waltham, MA 02451 (US). (72) Inventors: JENKINS, David; c/o Tesaro, Inc., 1000 Win- ter Street North, Suite 3300, Waltham, MA 02451 (US). LAKEN, Haley; c/o Tesaro, Inc., 1000 Winter Street North, Suite 3300, Waltham, MA 02451 (US). IM, Ellie; c/o Tesaro, Inc., 1000 Winter Street North, Suite 3300, Waltham, MA 02451 (US). DIAZ, Allene; c/o Tesaro, Inc., 1000 Winter Street North, Suite 3300, Waltham, MA 02451 (US). LU, Sharon; c/o Tesaro, Inc., 1000 Winter Street North, Suite 3300, Waltham, MA 02451 (US). (74) Agent: ESPINO, Christine, G. et al.; Proskauer Rose LLP, One International Place, Boston, MA 02110 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) with sequence listing part of description (Rule 5.2(a)) 1-1 O \" (57) : The present invention provides methods of administering certain PD-1 binding agents to patients having cancer. Dosage 0 regimens for compositions comprising a PD-1 binding agent are also explicitly provided. (54) Title: METHODS OF TREATING CANCER WITH ANTI-PD-1 ANTIBODIES