baber/WOPTO huggingface dataset:
Patent CA-2768516-A1 (CA)
Title: Superconducting article with prefabricated nanostructure for improved flux pinning
Inventor: SELVAMANICKAM VENKAT
IPC: B82B3/00
Filed: 2010-07-27
Abstract: A superconducting article comprises a substrate, a buffer layer overlying the substrate, and a high-temperature superconducting (HTS) layer overlying the buffer layer. The HTS layer includes a plurality of nanorods. A method of forming a superconducting article comprises providing a substrate, depositing a buffer layer overlying the substrate; forming a nanodot array overlying the buffer layer; depositing an array of nanorods nucleated on the nanodot array; and depositing a high-temperature superconducting (HTS) layer around the array of nanorods and overlying the buffer layer.
Patent CA-2768749-A1 (CA)
Title: Inhibitors of jnk
Inventor: GONG LEYI
IPC: C07D403/04
Filed: 2010-08-06
Abstract: The invention relates to JNK inhibitors and corresponding methods, formulations, and compositions for inhibiting JNK and treating JNK-mediated disorders. The application discloses JNK inhibitors, as described below in Formula I: wherein p, q, Y', r, R1, R2, X, X1, X2, X3, and X4 are as defined herein. The compounds and compositions disclosed herein are useful to modulate the activity of JNK and treat diseases associated with JNK activity. Disclosed are methods and formulations for inhibiting JNK and treating JNK-mediated disorders, and the like, with the compounds, and processes for making said compounds, and corresponding compositions, disclosed herein.
Patent CA-2771901-A1 (CA)
Inventor: GAMM DAVID M
IPC: C12N5/079
Filed: 2010-08-24
Abstract: Methods for producing substantially pure cultures of human neural retinal progenitor cells, forebrain progenitor cells, and retinal pigment epithelial cells are disclosed. In addition, the successful differentiation of human embryonic stem cells and human induced pluripotent stem cells through the major developmental stages of human retinogenesis is disclosed.
Patent CA-2772172-A1 (CA)
Title: Methods to improve the compatibility and efficiency of powdered versions of microfibrous cellulose
Inventor: SWAZEY JOHN MCARTHUR JR
IPC: C09K8/08
Filed: 2010-09-08
Abstract: A method for improving the performance of a powdered microfibrous cellulose (MFC) composition is provided. The method involves degrading a co-agent in the powdered MFC composition using a polymer degrader. The polymer degrader does not substantially degrade the MFC.
Patent CA-2773306-A1 (CA)
Inventor: HILFIKER ROLF
IPC: C07D279/18
Filed: 2010-09-23
Abstract: Substantially pure methylthioninium chloride pentahydrate form A is prepared from methylthioninium chloride by phase equilibration of suspensions, crystallization or solvent evaporation, whereby the water content of the solvent corresponds to a water activity of at least 0.4 at 25°C, and controlled drying of said methylthioninium chloride pentahydrate form A within its stability ranges of humidity, pressure and temperature.
Patent CA-2774732-A1 (CA)
Title: Dosage regimen for administering an epcamxcd3 bispecific antibody
Inventor: ZUGMEIER GERHARD
IPC: A61P35/00
Filed: 2010-09-20
Abstract: The present invention relates to a method (dosage regimen) for administering an EpCAMxCD3 bispecific antibody to a human patient, comprising (a) administering continually a first dose of said antibody for a first period of time; and consecutively (b) administering continually a second dose of said antibody for a second period of time, wherein said second dose exceeds said first dose. The methods of the invention (and likewise the dosage regimen of the invention) are also suitable for treating EpCAM positive epithelial cancer cells in a human patient, or for ameliorating and/or preventing a medical condition mediated by the continued administration of an EpCAMxCD3 bispecific antibody to a human patient. The present invention also relates to the use of an EpCAMxCD3 bispecific antibody for the preparation of a pharmaceutical composition to be used in a method as defined in any one of the preceding claims. A pharmaceutical package or kit comprising the first dose and the second dose as defined in the methods/dosage regimen of the present invention is disclosed as well.
Patent CA-2775986-A1 (CA)
Inventor: BONZER CLARICE
IPC: A47D13/08
Filed: 2012-04-25
Abstract: A multi-use pillow is constructed of a pillow body having a medial region and two arms that extend from the medial region. The pillow body also has a curved exterior periphery and an interior periphery that defines a well. A plurality of use-defining images are positioned on the pillow body at locations indicative of where a particular use of the pillow may occur. Also, use-defining text may also be placed on the pillow body adjacent to or separate from each of the use-defining images. In this way, a user is provided with a variety of visual prompts about how the pillow may be used.
Patent CA-2778447-A1 (CA)
Title: Catalyzed olefin insertion
Inventor: PENG SHENG
IPC: C07C17/269
Filed: 2010-10-22
Abstract: A process for the insertion of a partially fluorinated olefin into a fluorinated iodide in the presence of a nickel catalyst at a temperature of a maximum of 150°C with an initial rate of 0.01 mole/hour without loss of selectivity is disclosed, as well as use of the process for insertion of a perfluorinated olefin with an initial rate of 0.04 mole/hour.
Patent CA-2782484-A1 (CA)
Title: Mybl2 peptides and vaccines containing the same
Inventor: NAKAMURA YUSUKE
IPC: A61K39/00
Filed: 2010-12-02
Abstract: Peptide vaccines against cancer are described herein. In particular, epitope peptides derived from the MYBL2 gene that bind to HLA antigen and have cytotoxic T lymphocyte (CTL) inducibility, more particularly peptides having the amino acid sequence of SEQ ID NO: 5 and fragments thereof, are provided. The present invention further extends to peptides that include one, two, or several amino acid insertions, substitutions or additions to the aforementioned peptides or fragments, provided they retain cytotoxic T cell inducibility. Also provided as nucleic acids encoding any of the aforementioned peptides, antigen-presenting cells and isolated CTLs that target such peptides, and pharmaceutical agents and compositions including any of the aforementioned peptides, nucleic acids, and APCs as active ingredients. The components of the present invention have particular utility in connection with the treatment and/or prophylaxis (i.e., prevention) of cancers (tumors), and/or the prevention of a postoperative recurrence thereof.
Patent CA-2783929-A1 (CA)
Title: 5-amino-4-hydroxypentoyl amides
Inventor: KALAYANOV GENADIY
IPC: C07D417/12
Filed: 2010-12-10
Abstract: HIV inhibitors of formula (I) wherein R1 is halo, C1-4alkoxy, or trifluoromethoxy; R2 is a group of formula (A); R3 is a group of formula (B); R4 is a group of formula (C); n is 0 or 1; A is CH or N;  R5 and R6 are hydrogen, C1-4alkyl, or halo; R7 and R8 are independently C1-4alkyl or C1-4alkoxyC1-4alkyl; R9 is C1-4alkyl, cyclopropyl, trifluoromethyl, C1-4alkoxy, or dimethylamino; R10 is hydrogen, C1-4alkyl, cyclopropyl, trifluoromethyl, C1-4alkoxy, or dimethylamino;  pharmaceutically acceptable addition salts and solvates thereof;  pharmaceutical compositions containing these compounds as active ingredient and processes for preparing said compounds. (see formula I) (see formula A) (see formula B)
Patent CA-2783982-A1 (CA)
Inventor: RUEHLMANN JAMES GERARD
IPC: B68G5/02
Filed: 2012-07-27
Abstract: Mattress assemblies that provide user comfort and increased airflow generally include multilayered foams having open celled structures. Viscoelastic foams can be utilized having intact windows between adjacent cells of less than 50 percent.
Patent CA-2784210-A1 (CA)
Inventor: BERGEN GARY
IPC: A01C7/20
Filed: 2012-07-30
Abstract: A seeder includes a frame on ground wheels defining tool bars for seeding elements spaced across the frame. Each element includes a pair of parallel arms connected to the tool bar bracket forming a parallel linkage for up and down movement of a support arm connected at a rear end and carrying the packer wheel.  A spring applies a downward spring force on the parallel linkage to apply a downward force on the packer wheel so that the spring force increases as the parallel arms pivot upwardly and decreases as the parallel arms pivot downwardly.  A control device is arranged to raise and lower the tool bar in response to a detected value of a sensor so as to change the angle of the parallel linkage and change the spring force. A cam controlled double rack adjustment of the height of the opener allows the user to change seeding depth.
Patent CA-2784381-A1 (CA)
Inventor: HILLIAM KENNETH G
IPC: H01S3/10
Filed: 2012-07-20
Abstract: This Laser invention is intended to provide greater: safety, efficiency, output power, Pulse or CW Energy, design simplification and fixed / running cost savings for Single &  Multi Modes.  The Laser Output Photon Emissions are ejected differently than Laser energy amplification emissions which are created by light energy resonance through reflections of a pair of highly aligned and polished mirrors. Lasers require cooling and vibration protection to avoid lower efficiency and laser destruction. Few of the Output Light Waves are collimated and in phase.  This invention uses a different energy delivery approach. The Light Source Pumped Energy is manipulated in two distinct steps. Step 1: Light behaves as an Electro-Magnetic Wave and as a Negatively-Charged Photon. Electret technology can make permanently negatively charged ceramics or plastics in many shapes which can repel electrons. The plastic or the ceramic inner surface of a Tube or Barrel can be varied and permanently negatively charged.  Coherent and non-coherent waves are compressed or bundled into a narrow collective beam.  Step 2: the Closed End of the Tube holds the eg. LEDs, Laser Diodes or Flash Tube light energy pump source. A variable dynamically negatively charging plate repels the rows of collimated waves / photons to the Output so most of the light energy is not absorbed by the Laser Body as heat losses. "Bundled Narrow Light Energy Projectiles are ejected by a Dynamically Negatively Charged Plate". Deflecting plates and fibers can redirect the beam.
Patent CA-2784842-A1 (CA)
Inventor: RODEVILLE NICOLAS
IPC: A61K8/38
Filed: 2010-12-22
Abstract: La présente invention se rapporte à l'utilisation des composés de formule (I). Elle se rapporte également à leur procédé de préparation et à leur application cosmétique ou dermatologique. Les composés de la présente invention agissent comme agent bactéricide. Ils sont de fait utiles dans le traitement de conditions associées à la présence de bactéries, plus spécifiquement de p acnes.
Patent CA-2785994-A1 (CA)
Inventor: HARMS JON
IPC: H02K1/27
Filed: 2010-07-08
Abstract: A Halbach array is radially disposed in an environment optimized for efficiency and controlled for efficient generation and use of power in order to generate, establish, and maintain a desired level of rotational energy with enhanced efficiency.
Patent CA-2789887-A1 (CA)
Inventor: SOLEM JAN ERIK
IPC: G06K9/46
Filed: 2012-09-17
Abstract: Systems, methods, and computer readable media for determining and applying face recognition parameter sets are described. In general, techniques are disclosed for identifying and constructing a unique combination of facial recognition discriminators into a "face feature vector" that has been found to be more robust (e.g., stable to image noise, a person's pose, and scene illumination) and accurate (e.g., provide high recognition rates) than prior art techniques. More particularly, a face feature vector may be generated by the combination of shape descriptors (e.g., as generated by two-dimensional and three-dimensional shape models) and texture descriptors (e.g., as generated by global and local texture models).
Patent CA-2790533-A1 (CA)
Title: Manually operated puck shooting machine for training hockey goaltenders
Inventor: LOCICERO MICHAEL A
IPC: A63B69/40
Filed: 2012-09-27
Abstract: The puck machine was designed for the user. The technology incorporated allows anyone with average strength to master this teaching tool for goaltenders in the hockey world. Two motors are used attached to circular discs with rubber edges, a tube full of pucks with one in the chamber for release, a thumb on the trigger release mechanism and the once stationary puck in the chamber is forced with piston like execution pushing the puck between the two wheels rotating inward. The technology used to place the shot anywhere effortlessly is the joint attaching the plate with the engines above on the plate and the wheels, release chamber and piston underside of the plate.
Patent CA-2792697-A1 (CA)
Inventor: DULL KENNETH M
IPC: B29C35/00
Filed: 2012-10-16
Abstract: A method for allowing air and volatiles to escape from a composite part on a tool surface being compacted by a flexible vacuum bag comprises placing an edge breather on the tool surface around the composite part inside the flexible vacuum bag, the edge breather comprising a sleeve of foraminous woven material having a substantially tubular form and positioned between the composite part and a seal, wherein the sleeve of foraminous woven material comprises a braid of at least two thermoplastic fibers, and allowing the air and volatiles to pass through the sleeve of foraminous woven material from edges of the composite part.
Patent CA-2795005-A1 (CA)
Inventor: SILZLE ANDREAS
IPC: H04R29/00
Filed: 2011-03-30
Abstract: An apparatus for measuring a plurality of loudspeakers arranged at different positions comprises: a test signal generator (10) for generating a test signal for a loudspeaker; a microphone device (12) being configured for receiving a plurality of different sound signals in response to one or more loudspeaker signals emitted by a loudspeaker of the plurality of loudspeakers in response to the test signal; a controller (14) for controlling emissions of the loudspeaker signals by the plurality of loudspeakers and for handling the plurality of different sound signals so that a set of sound signals recorded by the microphone device is associated with each loudspeaker of the plurality of loudspeakers in response to the test signal; and an evaluator (16) for evaluating the set of sound signals for each loudspeaker to determine at least one loudspeaker characteristic for each loudspeaker and for indicating a loudspeaker state using the at least one loudspeaker characteristic for the loudspeaker. This scheme allows an automatic, efficient and accurate measurement of loudspeakers arranged in a three-dimensional configuration.
Patent CA-2798927-A1 (CA)
Title: Image processing apparatus and method
Inventor: SATO KAZUSHI
IPC: H04N7/26
Filed: 2011-06-03
Abstract: The present technology relates to an image processing apparatus and a method capable of performing a quantization process or an inverse quantization process more suitable for contents of an image. A lossless decoding unit 202 decodes coded data read from an accumulation buffer 201 at a predetermined timing. A sub macroblock inverse quantization unit 221 obtains a quantization value for each sub macroblock by using a quantization parameter supplied from an inverse quantization unit 203 and returns the same to the inverse quantization unit 203. The inverse quantization unit 203 inversely quantizes a quantization coefficient obtained by decoding by the lossless decoding unit 202 by using the quantization value for each sub macroblock supplied from the sub macroblock inverse quantization unit 221.  The present technology may be applied to the image processing apparatus, for example.
Patent CA-2800271-A1 (CA)
Inventor: CHOI BYOUNG-JU
IPC: G06F11/30
Filed: 2010-09-07
Abstract: The present invention provides a system testing method. The method includes identifying a position of a process control block, approaching the position thereof, and monitoring performance factors thereof.
Patent CA-2805892-A1 (CA)
Title: A method for manufacturing a gas burner
Inventor: DORA MASSIMO
IPC: F23D14/46
Filed: 2012-05-17
Abstract: Method for manufacturing a gas burner of the type comprising a cup, provided with at least one tubular tapered part of a mixer with axial Venturi effect, and shaped to couple with a burner head provided with at least one flame-spreader, wherein said cup is made in a single piece by casting or die-casting in an apposite mould.  Such a method comprises, in sequence, the following steps: a) arranging a mould with at least two shells, for casting or die-casting the afore said cup; b) arranging at least one core which could be removably inserted into the respective mould, which has at least one jutting portion shaped with at least one tubular tapered part of the strickle of the afore said mixer with axial Venturi effect; c) inserting such a core into the mould and closing the afore said at least two mould shells so that the afore said at least one jutting portion of the core is retained, at least partially, at a distance from the opposite inner walls of the closed mould; the core and the mould being shaped so that at least one ending part of such a core replaces, at least partially, part of the perimetrical area of the cup defined by the mould; d) pouring or pressure-injecting molten metal material into the closed mould; e) opening the mould, drawing out the afore said core and then removing the die formed cup after the metal material is solidified; f) applying at least one closing plug to the side hole (or side holes) of the die formed cup which corresponds/ correspond to the ending part of the core which replaced part of the perimetrical area of the cup in the mould.
Patent CA-2807949-A1 (CA)
Inventor: KRAFT DANIEL L
IPC: G16H10/60
Filed: 2011-08-15
Abstract: Determining an optimal combination drug product for a particular patient includes a processor that receives patient information and determines an optimal combination drug product based on the received information. A system provides information regarding predicted events or pathologies based on received patient information and guidance on subsequent steps to ameliorate, treat or intervent. A drug production device includes a plurality of drug containers, coupled to a drug dispensing channel. A controller controls the dispensing of drug through each channel, a combination drug product is produced from dispensed drugs. A combination drug product includes a plurality of discrete units of a first drug, and a plurality of discrete units of a second drug. A transdermal patch includes a plurality of drug compartments, each containing a quantity of drug product, and a controller for controlling the release of drugs from each compartment. Feedback loop elements can enable iterations to optimized personalized doses.
Patent CA-2809012-A1 (CA)
Inventor: GRIFOLS LUCAS VICTOR
IPC: A61K35/16
Filed: 2013-03-07
Abstract: A device for treating cholesterol disorders and use of at least one treatment regime including two or more rounds of plasmapheresis to a patient having abnormal total cholesterol, abnormal LDL levels and/or abnormal HDL levels prior to treatment. Treatment according to the method results in decreased LDL levels in patients having abnormal LDL levels and increased HDL levels in patients having abnormal HDL levels. Each subsequent round of plasmapheresis is conducted weekly, but no more than twice per week.
Patent CA-2809828-A1 (CA)
Title: Regulatory element for heterologous protein production in the fruiting body of filamentous fungi
Inventor: SHI ZHIXIN
IPC: C12N1/15
Filed: 2011-08-30
Abstract: The present invention provides compositions and methods for regulating expression of nucleotide sequences in fungi. Compositions are novel nucleotide sequences for a tissue preferred promoter isolated from the Agaricus bisporus lectin gene. The sequences drive expression preferentially to fruit body tissue. A method for expressing a nucleotide sequence in fungi using the regulatory sequences disclosed herein is provided. The method comprises transforming a fungal cell to comprise a nucleotide sequence operably linked to one or more of the regulatory sequences of the present invention and regenerating a stably transformed fungus from the transformed cell.
Patent CA-2809912-A1 (CA)
Title: Method for the production of 5-fluoro-1h-pyrazolo[3,4-b]pyridine-3-carbonitrile
Inventor: FOLLMANN MARKUS
IPC: C07D471/04
Filed: 2011-08-31
Abstract: The invention relates to a method for producing 5-fluoro-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile of formula (I) which is used as an intermediate synthesis compound for producing medicaments, in particular medicaments for the treatment and/or prevention of cardiovascular diseases.
Patent CA-2810690-A1 (CA)
Inventor: LITZ KYLE E
IPC: C10G67/00
Filed: 2011-09-01
Abstract: A reaction system and method for removing heteroatoms from oxidized-heteroatom-containing hydrocarbon streams and products derived therefrom are disclosed. An oxidized-heteroatom-containing hydrocarbon feed is reacted in a reaction system thereby forming non-ionic hydrocarbon products. The products derived therefrom are useful as transportation fuels, lubricants, refinery intermediates, or refinery feeds.
Patent CA-2811269-A1 (CA)
Title: Dispositif d'etancheite a fourreau pour la traversee de cloison par une biellette d'un systeme de commande de l'orientation des pales de soufflante d'un turbopropulseur
Inventor: GALLET FRANCOIS
IPC: F02C7/28
Filed: 2011-09-12
Abstract: L'invention concerne un dispositif d'étanchéité pour la traversée de cloison par une biellette d'un système de commande de l'orientation des pales de soufflante d'un turbopropulseur. Le dispositif comprend un tube (60) destiné à être fixé sur la cloison (58) à étancher, et un fourreau (62) de forme tronconique destiné à être traversé par la biellette (50a), le fourreau pouvant coulisser axialement à l'intérieur du tube et ayant, au niveau de son extrémité la plus large, des moyens d'étanchéité avec le tube et, au niveau de son extrémité la plus étroite, des moyens de fixation étanche à une extrémité correspondante de la biellette.
Patent CA-2811441-A1 (CA)
Title: Optically sensing the depression of a touch-screen
Inventor: PEMBERTON-PIGOTT NIGEL PATRICK
IPC: G06F15/02
Filed: 2011-09-15
Abstract: An electronic device includes a touch-sensitive display and a sensor configured to detect a force that results in depression of the touch-sensitive display. The sensor includes an optical device that receives a reflection of an optical signal, wherein the force affects the reflection. The reflection may be a reflection of a pattern on a surface of the touch-sensitive display, wherein the force affects the reflection.
Patent CA-2811970-A1 (CA)
Inventor: MANCOSH DOUGLAS
IPC: C04B26/16
Filed: 2011-08-05
Abstract: A composite building material includes carpet waste having carpet fibers and adhesive, and an inorganic filler that includes fly ash. The composite building material may be produced by providing the carpet waste, mixing the carpet waste with the inorganic filler to produce a homogeneous blend, and forming the homogeneous blend into the composite building material. The composite building material may optionally include a base polymer, slack wax, and/or calcium carbonate.
Patent CA-2812093-A1 (CA)
Title: Oncolytic adenoviral vectors coding for monoclonal anti - ctla - 4 antibodies
Inventor: DIAS JOAO
IPC: A61K35/761
Filed: 2011-09-23
Abstract: The present invention relates to the fields of life sciences and medicine. Specifically, the invention relates to cancer therapies. More specifically, the present invention relates to oncolytic adenoviral vectors and cells and pharmaceutical compositions comprising said vectors. The present invention also relates to said vectors for treating cancer in a subject and a method of treating cancer in a subject. Furthermore, the present invention relates to methods of producing monoclonal anti-CTLA4 antibodies in a cell and increasing tumor specific immune response and apoptosis in a subject, as well as uses of the oncolytic adenoviral vectors for producing monoclonal anti-CTLA4 antibodies in a cell and increasing tumor specific immune response and apoptosis in a subject.