baber/WOPTO huggingface dataset:
Patent EA-006443-B1 (EA)
Title: Tripeptidyl peptidase inhibitors
Inventor: BRESLIN HENRY JOSEPH
IPC: A61K31/4184
Filed: 2001-10-24
Abstract: Describes compounds of formula (I) which are inhibitors of a membrane tripeptidyl peptidase responsible for the inactivation of endogenous neuropeptides such as cholecystokinis (CCKs). In said formula (I) n is an integer (0) or (1); X represents -(CR<4>R<5>)m- wherein m is and integer (1) or (2); R<4> and R<5> are each independently from each other hydrogen or C1-4alkyl; R<1> is C1-6alkylcarbonyl optionally substituted with hydroxy; C1-6alkloxycarbonyl; aminoC1-6alkylcarbonyl wherein the C1-6alkyl group is optionally substituted with C3-6cycloalkyl ; mono- and di(C1-4alkyl)aminoC1-6alkylcarbonyl; aminocarbonyl substituted with aryl; C1-6alkylcarbonyloxyC1-6alkylcarbonyl; C1-6alkyloxycarbonylaminoC1-6alkylcarbonyl wherein the amino group is optionally substituted with C1-4alkyl; an amino acid; C1-6alkyl substituted with amino; or arylcarbonyl; R<2> is an optionally substituted (5)-membered heterocycle, etc. The invention further relates to methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use as a medicine of such compounds.
Patent EA-006741-B1 (EA)
Title: Peptide composition comprising camptothecin derivative (variants), method for manufacturing thereof and use
Inventor: AHMAD IMRAN
IPC: A61K47/48
Filed: 2001-11-09
Abstract: The present invention is for novel compositions and methods for treating diseases caused by cellular proliferation, particularly, for treating cancer in mammals and more particularly in humans. The therapeutic compositions of the present invention include SN-38 lipid complexes in which the complexes can contain any of a variety of neutral or charged lipids and, desirably, cardiolipin. The compositions are capable of efficiently incorporating SN-38 into complexes and are capable of solubilizing relatively high concentrations of SN-38.
Patent EA-007380-B1 (EA)
Title: Surface coated capsules
Inventor: TAKUBO TAKASHISA
IPC: A61K47/36
Filed: 2002-10-23
Abstract: A capsule is proposed including a physiologically acceptable nonionic surfactant coating, wherein the coating weight of the nonionic surfactant is 10 to 200 ppm based on the weight of an empty capsule. The coating provides excellent glide, anti-static properties and printing quality without preventing its degradation.
Patent EA-005979-B1 (EA)
Title: Method and apparatus for making cigarette filters with a centrally located flavored element
Inventor: LANIER ROBERT C JR
IPC: A24D3/02
Filed: 2003-03-31
Abstract: A filter making apparatus includes a positioning device having a passageway therethrough, with the passageway guiding a continuous flavor element (70) such as a continuous strand of textile material from an inlet of the passageway to an outlet of the passageway. A liquid flavorant (70) is introduced into the passageway at a desired flow rate and the strand of material carries the supplied liquid flavorant out of the positioning device at a rate substantially equal to the desired flow rate.
Patent EA-007333-B1 (EA)
Title: Dithianon-based fungicidal mixtures
Inventor: AMMERMANN EBERHARD
IPC: A01N43/54
Filed: 2003-06-30
Abstract: The invention relates to fungicidal mixtures that contain A) the compound of formula (I),andB) a pyrimidine derivative of formula (II),wherein R represents methyl, cyclopropyl or 1-propinyl, in a synergistically effective amount. The invention also relates to a method for controlling parasitic fungi using mixtures of the compounds (I) and (II) and the use of compounds (I) and (II) in the production of such mixtures.
Patent EA-008671-B1 (EA)
Title: Fiber assisted emulsion system
Inventor: WILLBERG DEAN
IPC: C09K8/02
Filed: 2003-09-15
Abstract: Emulsions, either water-in-oil or oil-in-water, may be formed by combining an aqueous component, a non-aqueous component and a surfactant in combination with fibers. The fibers decrease the time and energy required to form the emulsion and, in some cases, allow emulsion formation that would not be possible with the use of such fibers.
Patent EA-010443-B1 (EA)
Title: Gaming machine
Inventor: OKADA KAZYO
IPC: G07F17/34
Filed: 2005-11-25
Abstract: A gaming machine is proposed including: an information reading means that reads object information from a reading object provided with a storage medium in which the object information is stored, the reading object being mountable on the gaming machine; a game processing means that performs game processing to provide to a player a game in a plurality of game states including a normal game state and a bonus game state in which a grater advantage is provided to the player than in the normal game state; and a display means that displays an effect related to the game, wherein the game processing means controls a frequency of occurrence of the effect to be displayed on the display means during the game based on the object information read from the reading object by the information reading means.
Patent EA-011931-B1 (EA)
Title: Chewable, suckable and swallowable tablet containing a calcium-containing compound as an active substance
Inventor: OLSEN PEDER MOHR
IPC: A61J3/06
Filed: 2005-05-24
Abstract: The present invention relates to a nutriceutical and/or pharmaceutical composition for oral use containing a calcium-containing compound. The composition is in the form of tablets that are designed so that they have an acceptable taste and mouthfeel, whereby the tablets are chewable or suckable, and at the same time the tablets fulfil the requirements with respect to technical properties in order to ensure that the tablets can be dispensed by means of a dose-dispensing machine.
Patent EA-010586-B1 (EA)
Title: Immunogenic compositions of cyclic peptides derived from the beta-amyloid peptide
Inventor: ZURBRIGGEN RINALDO
IPC: C07K7/64
Filed: 2005-12-21
Abstract: The present invention relates to methods and compositions for the elicitation of an immune response against amyloid betapeptides, in particular by the combinatory use of virosomes as adjuvants and a synthetic amyloid beta-peptide antigen.
Patent EA-012050-B1 (EA)
Title: Glass composition for production of glazing absorbing ultraviolet and infrared radiation
Inventor: TWEYSSEDRE LAURENT
IPC: C03C3/087
Filed: 2006-02-06
Abstract: The invention relates to a glass composition for production of glazing absorbing ultraviolet and infrared radiation, comprising the following oxides with a content by weight varying within the given limits SiO65 - 80 %, AlO0 - 5 %, BO0 - 5 %, CaO 5 - 15 %, MgO 0 - 2 %, NaO 9 - 18 %, KO 0 - 10 %, BaO 0 - 5 %, characterised in further comprising the following absorbing agents with a content by weight varying within the given limits: FeO(total iron) 0.7 - 1.6 %, CeO0.1 - 1.2 % TiO0 - 1.5 % the glass having a redox factor less than or equal to 0.23 and having no tungsten oxide WO.
Patent EA-011735-B1 (EA)
Title: Coated paper for offset printing
Inventor: HAENEN JEAN-PIERRE
IPC: D21H19/84
Filed: 2006-07-12
Abstract: The invention relates to a single or multiple coated printing sheet in particular but not exclusively for offset printing sheet with an image receptive coating layer on a paper substrate. Unexpectedly short converting times and times until reprinting can be achieved by choosing a coating, in which the image receptive coating layer comprises a top layer and/or at least one second layer below said top layer, said top and/or second layer comprising a pigment part, wherein this pigment part is composed of 1 to 95 preferably of 80 to 95 parts in dry weight of a fine particulate carbonate and/or of a fine particulate kaolin or clay and 1 to 100, preferably 6 to 25 parts in dry weight of a fine particulate silica, and a binder part, wherein this binder part is composed of 5 to 20 parts in dry weight of binder and less than 4 parts in dry weight of additives. Furthermore, methods for making such a printing sheet and uses of such a printing sheet are disclosed.
Patent EA-014459-B1 (EA)
Title: Multifunctional protection system for a sports ground
Inventor: HANSEZ-GONNE BERNARD
IPC: A63C19/12
Filed: 2007-08-28
Abstract: The present invention relates to a protection system for a sports ground, comprising a frame-chest containing a protection cover, said frame-chest being capable of displacement along the entire length of the ground while unfolding or folding said protection cover using an unfolding and folding mechanism, wherein said frame-chest is connected to a cable network previously arranged on the sports ground, said cables being driven by powered pulleys for ensuring the displacement of said frame-chest on said sports ground.
Patent EA-017356-B1 (EA)
Title: The geolattice focused in one direction and a building element on its basis
Inventor: KOSHURNIKOV DENIS PETROVICH
IPC: B29D28/00
Filed: 2010-01-27
Abstract: The invention relates to area of construction and concerns basically the devices strengthening road clothes, especially on the weak grounds. It can be applied also as a special reinforcing or protecting element in other various building designs. The task of the invention consists in increase of durability of the geolattice focused in one direction and reliability of a building element on its basis. The building element contains a basic element, for example, a layer of rubble on which the geolattice is laid. The geolattice (fig. 2) contains parallel lines of strips (2) of replacement and orientation in one direction of a material on the basis of polyolefine, for example polyethylene or a mixture of polyolefines. The strips form parallel lines of oval windows (3) and parallel lines of edges (4) which are perpendicular to the lines of strips. The edges contain in places of the crossing with strips thickenings (5) between which additional thickenings (6) that are greater in section are located. Variant of performance of a ratio of thickness in a design of such lattice can be performance of thickenings (5) with greater thickness of strips (2) no more than in 2.2 times, and additional thickenings (6) - no more than in 2.5 times. For increase of coupling qualities of the lattice it is recommended to put a superficial grid (7) at least on one of its sides. For increase of elasticity and durability of the lattice it is reasonable to carry out the strips with thickness on the edges (8) more than in their average part (9), for example, in 1.5 times. For maintenance of the best opportunity of deduction of a loose or lumpy material on each line of strips, it is desirable in places of transition (10) of the strips to make biases in thickenings (5).
Patent EA-017929-B1 (EA)
Title: Method for the production of sulphonylpyrroles as hdac inhibitors
Inventor: MUELLER MATTHIAS
IPC: A61K31/40
Filed: 2009-03-11
Abstract: Process for the preparation of a compound of formula (I) wherein R1, R2, R3, R4, R5 and R6 have the meanings as defined in the specification, comprising the step of reacting an acrylic acid chloride compound of formula (II'), wherein R1, R2, R3, R4, R5 and R6 have the meanings as defined in the specification, with aqueous hydroxylamine and optionally converting the resulting compound into an acid addition salt thereof.
Patent EA-022168-B1 (EA)
Title: Method for production of compacted intermediate dimaleate bibw 2992 and solid tablets prepared from such intermediate
Inventor: MESSERSCHMID ROMAN
IPC: A61P35/00
Filed: 2009-06-05
Abstract: The invention relates to compacted intermediates comprising dimaleate BIBW 2992 (BIBW 2992 MA) in the form of a powder prepared using a combined roller compaction and sieving step from BIBW 2992 MA. The invention also discloses solid oral formulations providing an immediate release profile of the active substance, made from said compacted intermediate ready for use/ingestion, such as uncoated or film-coated tablets.
Patent EA-018022-B1 (EA)
Title: Method for manufacturing fischer-tropsch synthetic crude oil
Inventor: TASAKA KAZUHIKO
IPC: B01J38/00
Filed: 2009-03-12
Abstract: Disclosed is a method for removing magnetic particles from Fischer-Tropsch synthetic crude oil, comprising: a solid-liquid separation process in which solid components are separated from synthetic crude oil formed by a Fischer-Tropsch synthesis reaction; and a magnetic separation process in which magnetic particles present in the synthetic crude oil that has undergone the solid-liquid separation process are trapped, and the magnetic particles are separated from the synthetic crude oil. The magnetic separation process is conducted using a high gradient magnetic separator having a cleaning solution introduction line that introduces a cleaning solution to intermittently wash the trapped magnetic particles, and a cleaning solution discharging line that discharges the cleaning solution after the solution is used to wash the magnetic particles.
Patent EA-022842-B1 (EA)
Title: Method for isolation of nucleic acids and a kit thereof
Inventor: PULLELA PHANI KUMAR
IPC: C12N15/10
Filed: 2011-01-06
Abstract: The present disclosure provides a method to isolate natural and artificial nucleic acids like deoxyribonucleic acid (DNA), ribonucleic acid (RNA) and peptide nucleic acid (PNA) from a solid or liquid sample using cotton. The cotton packed is such that a solution containing nucleic acids passes through it and the nucleic acids in solution are bound to the cotton in a medium optimal for binding. The nucleic acids are bound to cotton in such a way that, the bound nucleic acids can withstand multiple washes with liquid comprising water and gets eluted in an aqueous buffer, with which eluted nucleic acids can be directly used for amplification using PCR or for any other biochemical or molecular biology needs.
Patent EA-027113-B1 (EA)
Title: Complement pathway modulators and uses thereof
Inventor: ADAMS CHRISTOPHER MICHAEL
IPC: C07D417/06
Filed: 2013-05-03
Abstract: The present invention provides a compound of formula (I), a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides combinations of pharmacologically active agents and pharmaceutical compositions.
Patent EA-029562-B1 (EA)
Title: Non-invasive method for laser nano-diagnostics of cancer diseases
Inventor: MELEDIN VLADIMIR GENRIEVICH
IPC: G01N21/49
Filed: 2014-03-05
Abstract: The invention relates to the field of nanotechnology in examination of nanostructures in biological fluids using optical tools, and may be applied in medicine to dignostics of cancer or other diseases, particularly at early stages, and as well for assessment of treatment efficiency or mass prevention screening of population. The non-invasive method for laser nano-diagnostics of cancer diseases comprises measurements of time-and-frequency fluctuations of light-diffusion intensity in supernatants of patients' centrifuged urine samples using laser correlation spectroscopy technique in 1-10Hz range, determining diagnostic index values by calculation of mean-square deviations of measured time-and-frequency fluctuations of light-diffusion intensity of patients' urine samples, and diagnostics of diseases based on analysis of diagnostic index value positions relative to allowable interval.
Patent EA-030149-B1 (EA)
Title: Balanced mixing, grinding and activating device
Inventor: AFANASIEV ALEXEY GAVRIILOVICH
IPC: B22C5/04
Filed: 2015-10-05
Abstract: The invention is related to mixing and grinding devices. A device for mixing, grinding and activating materials comprises a body, a rotatable cylindrical working container mounted on the body bearings, blades mounted by means of brackets on a rotatable rotor, wherein a loading device for material loading is mounted on one side of the working container, and the material discharge device is mounted on the other side of the working container, the blades with the brackets are mounted uniformly on the rotor, and the blades are mounted uniformly on the rotatable rotor to form at least one group consisting of four blades, wherein the second and the third blades are turned in respect of the first blade by 180°, and the fourth blade is mounted similarly to the first one; the groups of four blades are mounted in the same way as the first group of blades or they are turned at any angle relative to the first group; the working container rests additionally on at least one additional bearing assembly arranged between the four-blade groups; the additional bearing assembly between the four-blade groups is mounted on the rotatable rotor; the body of the additional bearing assembly of the working container is designed as a disk with holes.
Patent EA-028754-B1 (EA)
Title: Hinge device for doors
Inventor: BACCHETTI LUCIANO
IPC: E05F3/12
Filed: 2013-10-04
Abstract: A hinge device for rotatably moving and/or controlling during closing and/or opening a closing element (D), such as a door or a shutter, anchored to a stationary support structure (S), such as a wall or a frame, the device including a fixed element (10) anchored to the stationary support structure (S); a movable element (11) anchored to the closing element (D), said movable element (11) and said fixed element (10) being mutually coupled for rotating said movable element (11) about a first longitudinal axis (X) between an open position and a closed position of said element (D); at least one slider (30, 60) movable along said axis (X) between a first end-stroke position of said slider (30, 60), corresponding to one of said open or closed positions of said element (D), and a second end-stroke position of said slider (30, 60), corresponding to the other of said open or closed positions of said element (D).
Patent EA-032518-B1 (EA)
Title: Arrangement for cooling channels in an electrode system
Inventor: OLLILA JANNE
IPC: F27D11/08
Filed: 2014-08-20
Abstract: The provided invention relates to an arrangement for cooling channels in an electrode column assembly of an electric arc furnace, wherein the lower part of the electrode column assembly is provided with a contact shoe ring formed of a plurality of contact shoe elements (31), a pressure ring formed of a plurality of pressure blocks, and a heat shield located above the pressure ring and formed of a plurality of heat shield segments. The contact shoe elements (31) and/or the pressure blocks are provided with channels (35, 36) for a cooling liquid to flow therein. The channels (35, 36) made in the material of the contact shoe elements (31) and/or the pressure blocks extend obliquely downwards from the upper ends (33) of said contact shoe elements (31) and/or the pressure blocks near to the lower ends (34) of the same. At least two of said oblique channels (35, 36) in a same contact shoe element (31) and/or pressure block join together at their lower ends near the lower ends (34) of the contact shoe elements (31) and/or the pressure blocks to form a continuous channel (35, 36) in each contact shoe element (31) and pressure block.
Patent EA-036501-B1 (EA)
Title: Cement compound and method for the production thereof
Inventor: BUCHWALD ANJA
IPC: C04B7/24
Filed: 2015-06-05
Abstract: The present invention relates to a cement compound. The invention also relates to a method for producing such a cement compound. More in particular, the present invention relates to a cement compound comprising at least a reactive glass compound, an alkaline activator and a filler, and optionally additives, said reactive glass compound comprising at least 35 wt.% CaO, at least 25 wt.% SiO2 and at least 10 wt.% Al2O3, and optionally other oxides.
Patent EA-036093-B1 (EA)
Title: Method for connecting subscribers in the event of mutual calling and device for implementing same
Inventor: MIHAILOV KONSTANTIN IGOREVICH
IPC: H04M7/06
Filed: 2017-04-26
Abstract: The invention relates to the field of telephone communication and pertains to improving same so as to satisfy the needs of subscribers in the event of mutual calling. A method for connecting subscribers during mutual calling and a device for implementing same are carried out by processing signals for making a decision regarding connecting the subscribers in an additional service-management node 6 connected to a service management node 3 and to switches 2 and 5, and the subscribers 1 and 4 being connected, during mutual calling, in a network node 7 which is connected to switches 2 and 5, outside of switches 2 and 5.
Patent EA-032785-B1 (EA)
Title: Piezoelectrically actuated optical lens
Inventor: CRAEN PIERRE
IPC: G02B3/14
Filed: 2015-07-17
Abstract: There is presented a transparent optical device element (700) comprising an optical lens (744), comprising one or more piezoelectric actuators (206, 208, 210), wherein said optical lens (744) comprises an optical aperture (632), and wherein the optical device element furthermore comprises a passivation layer (312, 314, 742, 628) placed on said optical lens, said passivation layer comprising a barrier layer (312)forming a humidity barrier, and being located on at least a portion of said cover member, where said portion of said cover member is intersected by the optical axis, and on said piezoelectric actuators, and wherein the passivation layer furthermore comprises one or more further layers (628) located on at least said portion of said cover member being intersected by the optical axis, wherein said passivation layer forms an anti-reflection coating for said optical lens (744) at least along the optical axis (634).
Patent EA-033570-B1 (EA)
Title: Indirect heat exchanger
Inventor: BEAVER ANDREW
IPC: F28F1/02
Filed: 2017-10-09
Abstract: An improved indirect heat exchanger is provided which is comprised of a plurality of coil circuits, with each coil circuit comprised of indirect heat exchange section tube runs or plates. Each tube run or plate has at least one change in its geometric shape. Alternatively, each tube run or plate may have a progressive change in its geometric shape proceeding from the inlet to the outlet of the circuit. The change in geometric shape along the circuit length allows simultaneously balancing of the external airflow, internal heat transfer coefficients, internal fluid side pressure drop, cross sectional area and heat transfer surface area to optimize heat transfer.
Patent EA-036635-B1 (EA)
Title: Distributed optical fiber perimeter security system, sound restoration system and method
Inventor: WEI YUFENG
IPC: G08B13/00
Filed: 2016-08-17
Abstract: A distributed optical fiber perimeter security system, and sound restoration system and method are disclosed. The sound restoration system is applied to the distributed optical fiber perimeter security system monitoring several protection areas. The sound restoration system comprises a laser generation mechanism (11) for providing a laser signal; a beam splitting mechanism (12) for splitting the laser signal into multiple input optical signals; a plurality of optical fiber Michelson interferometer mechanisms (13) corresponding to each of the protection areas, wherein each of the optical fiber Michelson interferometer mechanisms (13) receives an input optical signal and outputs, in response to a surrounding sound pressure, an interference signal; and an audio output mechanism (14) for receiving the interference signal and when an alarm signal of any of the protection areas is received, outputting an audio signal restored according to the interference signal of the protection area. The system can help a user make a further confirmation and determination on an occurrence of abnormal events such as intrusions.
Patent EA-038402-B1 (EA)
Title: Adenovirus polynucleotides and polypeptides
Inventor: AMMENDOLA VIRGINIA
IPC: C12N15/861
Filed: 2016-06-10
Abstract: There is provided inter alia an isolated polynucleotide which encodes a polypeptide selected from the group consisting of: (a) a polypeptide having the amino acid sequence according to SEQ ID NO: 1, (b) a functional derivative of a polypeptide having the amino acid sequence according to SEQ ID NO: 1, wherein the functional derivative has an amino acid sequence which is at least 80% identical over its entire length to the amino acid sequence of SEQ ID NO: 1, and (c) a polypeptide having the amino acid sequence according to SEQ ID NO: 3.