baber/WOPTO huggingface dataset:
Patent NZ-231815-A (NZ)
Title: Method for amplifying and assaying a target rna segment
Inventor: GINGERAS THOMAS RAYMOND
IPC: C12Q1/6865
Filed: 1989-12-15
Abstract: The present disclosure provides details of an invention comprising an amplification system for the detection of target nucleic acids, most particularly target nucleic acid sequences, in an isothermal setting wherein all of the reagents necessary to conduct the amplification are present and the reactions are self-sustaining and continuous. Featured is a selective enzymatic digestion of a RNA/DNA duplex, formed by hybridization of a DNA primer with target nucleic acid, thus freeing the DNA strand for further hybridization followed by primer extension to provide a DNA duplex that can serve as a template for production of a plurality of transcripts that can be recycled and/or detected as such for deduced presence of target nucleic acid sequence. <IMAGE>
Patent NZ-237535-A (NZ)
Title: Carrier for binding anti-phospholipid antibodies, its use in immunoassays and kits and blood protein which enhances binding ability of antiphospholipid antibody
Inventor: MATSUURA EIJI
IPC: G01N33/92
Filed: 1991-03-21
Abstract: A carrier for binding an antiphospholipid antibody used in the immunodiagonosis of antiphospholipid antibody syndromes with a high accuracy, contains a phospholipid bound thereto and is treated with a purified serum albumin and a surfacant. It is possible to carry out the immunodiagnosis of antiphospholipid antibody syndromes more accurately than before by using a fractionation prod. or protein which is obtd. from animal serum or plasma and can enhance the capability of binding between a phospholipid and an antibody specifically present in antiphospholipid antibody syndromes.
Patent NZ-238046-A (NZ)
Title: Low profile container closure having anti-drip dosing cap and cooperating spout
Inventor: SEGATI UMBERTO D I
IPC: B65D41/26
Filed: 1991-05-03
Abstract: A low profile closure which includes a coupling member (16) which is mounted on a container dispensing opening (14), and an open ended dosing cap (18) including a boundary wall ( 64 ) which is dimensioned for removable attachment to an interior surface of the coupling member. The coupling member includes an open ended body portion (26) formed by an upright boundary wall (28), and a top peripheral edge which defines an outwardly projecting spout (36). An exterior surface of the dosing cap is arranged in conforming frictional relation to the outwardly projecting spout to provide a low profile closure. Cooperating external and internal threads (70,40) respectively disposed on the cap boundary wall and coupling body portion are employed to removably fasten the cap in the coupling member. <IMAGE>
Patent NZ-248602-A (NZ)
Title: Isolation, characterisation and cloning of growth hormone releasing hormone receptor
Inventor: THORNER MICHAEL OLIVER
IPC: C12N/
Filed: 1993-09-07
Abstract: Growth hormone releasing hormone (GHRH) receptor binding has been characterized using a unique binding assay utilizing iodinated GHRH probes. Photoaffinity GHRH probes have been constructed which allow for photolabeling and characterization of the receptor. In addition, high affinity biotinylated GHRH analogs have been constructed. Solubilization of GHRH-R/GHRH complexes and extraction of specifically bound GHRH using a mild detergent solution, followed by affinity chromotography, leads to a substantially purified GHRH-R isolate. Electrophoretic treatment of the GHRH-R isolate produces GHRH-R of sufficient purity to conduct sequencing of the receptor. Cloning of a gene encoding for polypeptides (protein or fragments thereof) having GHRH-R activity is accomplished using a bacterial host, and the cloned gene is expressed in a mammalian cell line.
Patent NZ-257215-A (NZ)
Title: Diagnosis or prognosis of alzheimers using the presence of apolipoprotein e type 4 as an indicator and apolipoprotein e isoform specific antibodies
Inventor: ROSES ALLEN DAVID
IPC: C12Q1/68
Filed: 1993-09-30
Abstract: Methods of diagnosing or prognosing Alzheimer's disease in a subject are disclosed. The methods involve directly or indirectly detecting the presence or absence of an apolipoprotein E type 4 (ApoE4) isoform or DNA encoding ApoE4 in the subject. The presence of ApoE4 indicates the subject is afflicted with Alzheimer's disease or at risk of developing Alzheimer's disease. A novel immunochemical assay for detecting the presence or absence of the Apoliprotein E (ApoE) E4 allele in a subject is also disclosed.
Patent NZ-267567-A (NZ)
Title: Treatment of inflammatory conditions using various indole, benzoquinone and benzofuran derivatives; method of plant material extraction; celery seed extract
Inventor: DAUNTER BRIAN
IPC: A61K31/16
Filed: 1994-06-24
Abstract: A method for the treatment of an inflammatory complaint including the step of administration of a compound of general formulae (I to XII) described herein in figure or mixtures thereof to a subject suffering from said inflammatory complaint. There is also included a therapeutic agent for relief of inflammatory complaints which includes a compound of general formulae (I to XII) as described in figure or mixtures thereof in combination with an appropriate filler which is preferably dicalcium phosphate. The invention also includes within its scope plant extracts which may contain one or more of the above-mentioned compounds and in particular plant extracts of the genus Umbelliferae, celery (Apium graveolens), parsley (Petroselimun hortense) and dill (Anethum graveolens). It is believed that compounds of the above-mentioned formulae and in particular butylphthalide, sedanenolide and sedanolide (in both cis and trans forms otherwise known as essential oils which are mainly derived from plants) mimic the physiological response of essential fatty acids and also their prostaglandin analogues.
Patent NZ-269640-A (NZ)
Title: Transformed plants containing modified ethylene response nucleic acid and coding sequences therefor
Inventor: MEYEROWITZ ELLIOTT M
IPC: C12N15/82
Filed: 1994-06-30
Abstract: The invention includes transformed plants having at least one cell transformed with a modified ETR nucleic acid. Such plants have a phenotype characterized by a decrease in the response of at least one transformed plant cell to ethylene as compared to a plant not containing the transformed plant cell. Tissue and/or temporal specificity for expression of the modified ETR nucleic acid is controlled by selecting appropriate expression regulation sequences to target the location and/or time of expression of the transformed nucleic acid. The plants are made by transforming at least one plant cell with an appropriate modified ETR nucleic acid, regenerating plants from one or more of the transformed plant cells and selecting at least one plant having the desired phenotype.
Patent NZ-294191-A (NZ)
Title: Process for preparing 4a,5,9,10,11,12-hexahydro-6h-benzofuro[3a,3,2-ef][2]benzazepine derivatives and intermediates thereof
Inventor: CZOLLNER LASZLO
IPC: C07C217/58
Filed: 1995-10-23
Abstract: The invention relates to processes for the preparation of 4a,5,9,10,11,12-hexahydro-6H-benzofuro(3a,3,2-ef)(2)benzazepine, or derivatives thereof. Furthermore, the invention also relates to the compounds formed during the preparation of 4a,5,9,10,11,12-hexahydro-6H-benzofuro(3a,3,2-ef)(2)benzazepine.
Patent NZ-310385-A (NZ)
Title: Novel derivatives of swainsonine, processes for their preparation and their use as therapeutic agents
Inventor: CARVER JEREMY
IPC: C07D471/04
Filed: 1996-06-07
Abstract: The invention relates to novel mannosidase inhibitors of formula (I'), wherein one of R1, R2, R3, R4, R5, and R6 represents amino, halo, thiol, alkoxy, alkyl, aryl, thioalkyl, or thioaryl, and the others of R1, R2, R3, R4, R5, and R6 represent hydrogen, hydroxyl, amino, halo, thiol, alkoxy, alkyl, aryl, thioalkyl, or thioaryl, with the proviso that R3 and R6 are not both hydrogen and R1 and R4 are not both hydrogen when one of R2 and R5 is hydroxyl and the other of R2 and R5 is alkyl; R2 and R5 are not both hydrogen and R1 and R4 are not both hydrogen when one of R3 and R6 is alkyl or aryl and the other of R3 and R6 is hydrogen or hydroxyl; and R2 and R5 are not both hydrogen and R3 and R6 are not both hydrogen when one of R1 and R4 is hydroxyl and the other of R1 and R4 is alkyl.
Patent NZ-313104-A (NZ)
Title: Separator
Inventor: PHILLIPS DONALD IAN
IPC: E02B5/08
Filed: 1996-07-26
Abstract: A separator for separating material (16) from a fluid is claimed.  The separator comprises an inlet, a separating chamber (20) in fluid communication with the inlet (6), a holding chamber, deflecting means (50) for deflecting material (16) entrained in or moving with fluid entering the separating chamber (20) from the inlet (6) towards the holding chamber and an outlet (8) for permitting flow of fluid from which the material has been removed from the separating chamber.  Deflecting means (50) is mounted for movement in separating chamber (20).
Patent NZ-334252-A (NZ)
Title: Heterocyclic metalloprotease inhibitors
Inventor: DE BISWANATH
IPC: A61K31/54
Filed: 1997-08-22
Abstract: These compounds, which are characterized by metalloprotease activity, are of the formula (I) or an optical isomer, diastereomer or enantiomer thereof, or a pharmaceutically-acceptable salt, or biohydrolyzable amide, ester, or imide thereof where: R1 is H; R2 is H, alkyl or acyl; A is COR or SO2R; X is CH2, O, S, SO, SO2, or NR; W is H or alkyl, or an alkylene, arylene, or heteoarylene bridge between two carbons forming a fused ring; Y is H, OH, SR, SOR, SO2R, alkoxy or amino; Z is nil, a spiro moiety or an oxo group substituted on the heterocyclic ring; and n is 1-3.
Patent NZ-500923-A (NZ)
Title: Process for knitting tubular articles in a single-cylinder circular knitting machine, typically for stockings, with stretching of threads by movement of sinker and needle
Inventor: GORGAINI MAURO
IPC: D04B9/00
Filed: 1999-11-09
Abstract: Backward and forward displacements of sinker 2 occur corresponding to the top stroke-end position of needle 1 such that a new stitch is formed on the upper edge of sinker tip 2a. The old stitch disengages as a consequence of the movement of needle 1 and sinker 2.
Patent NZ-506780-A (NZ)
Title: Branched polymer composition and method of manufacture
Inventor: CHISHOLM MICHAEL STEPHEN
IPC: C09D4/02
Filed: 1999-03-12
Abstract: A method of preparing a branched polymer comprising the steps of mixing together a monofunctional vinylic monomer with from 0.3-100 % w/w of a polyfunctional vinylic monomer and from 0.0001-50% w/w of a chain transfer agent and thereafter reacting said mixture to form a polymer. The resulting soluble branched polymers are useful as components of surface coatings and inks or as moulding resins.
Patent NZ-509474-A (NZ)
Title: Amino acid thrombin inhibitors
Inventor: GUSTAFSSON DAVID
IPC: A61K31/443
Filed: 1996-07-02
Abstract: Disclosed are compounds of the formula (I); wherein, p and q independently represent 0; R1 represents H; R2 represents H; R3 represents phenyl (which group is substituted by one or more of C1-4 alkyl, C1-4 alkoxy, Halo, hydroxy, cyano, nitro, methylenedioxy, trifluoromethyl, N(H)R27 or C(O)OR28; R27 represents H, C1-4 alkyl or C(O)R29; R28 and R29 independently represent H or C1-4 alkyl; R4 represents H or C1-4 alkyl; Y represents C1-3 alkylene optionally substituted by C1-4 alkyl, hydroxy, methylene or oxo; n represents 1; and B represents a structural fragment of formula IVa R5 represents H, halo or C1-4 alkyl; or a pharmaceutically acceptable salt thereof. Further disclosed is the use of compounds of the formula (I) in the preparation of a medicament for the treatment of a condition where the inhibition of thrombin is required; such as, use as an anticoagulant or, the treatment of thrombosis. (62) Divided out of 504312
Patent NZ-514811-A (NZ)
Title: Anticonvulsant derivatives useful in reducing blood glucose levels
Inventor: COTTRELL SANDRA C
IPC: A61K31/357
Filed: 2000-03-20
Abstract: A compound of formula (I) is used in the manufacture of a medicament useful for reducing blood glucose levels in a mammal; In formula (I): X is CH2 or oxygen; R1 is hydrogen or alkyl; and R2, R3, R4 and R5 are independently hydrogen or alkyl and, when X is CH2, R4 and R5 may be alkene groups joined to form a benzene ring and, when X is oxygen, R2 and R3 and/or R4 and R5 together may be a methylenedioxy group -O-C(R6)(R7)-O-; R6 and R7 are independently hydrogen or alkyl or can be joined to form a cyclopentyl or cyclohexyl ring.
Patent NZ-518919-A (NZ)
Title: Production of peptides by fedbatch cultivation of a microorganism
Inventor: CASTAN ANDREAS
IPC: C12P21/02
Filed: 2000-11-29
Abstract: A method for the production of recombinant peptides by fed-batch cultivation of a microorganism in a bioreactor containing a medium comprising organic carbon source, nitrogen source and mineral salts. The cultivation is carried out by the addition of the organic carbon source in oscillation feed and/or by oscillation variation of stirring speed, without exhaustion of the organic carbon source during the oscillation period, wherein the oscillation has a wave period of from about 1 to about 30 minutes. The microorganism is a biological host selected from the group consisting of bacteria, yeast and animal cell. The cultivation conditions remain aerobic.
Patent NZ-524003-A (NZ)
Title: A gas injection lance
Inventor: DUNNE MARTIN JOSEPH
IPC: C21C5/48
Filed: 2002-07-08
Abstract: A lance for injecting a pre-heated oxygen-containing gas into a vessel containing a bath of molten material is disclosed. The lance (26) includes an elongate gas flow duct (31) from which to discharge gas from the duct. The duct includes (i) inner and outer concentric carbon steel tubes (37, 39) which provide major structural support for the duct, (ii) cooling water supply and return passage means (43, 44) extending through the duct wall from the rear end to the forward end of the duct for supply and return of cooling water to the forward end of the duct, and (iii) a mechanical means in the form of lands (136) on the exterior surface of the duct adapted to hold a layer of frozen slag on the duct. The lance also includes a gas inlet (32) for introducing hot gas into the rear end of the duct. The lance also includes a tip means (36) joined to the concentric tubes at the forward end of the duct. The lance also includes a protective lining formed from a refractory or other material that is capable of protecting the duct from exposure to gas flow at 800-1400 °C through the duct. The lining is a non-metallic material with heat insulating properties when compared to the steel tubes. The lance also includes a swirl means (34) located in the duct for imparting swirl to gas flow through the forward end of the duct.
Patent NZ-527556-A (NZ)
Title: Gaming machine illuminating arrangement
Inventor: WILLIAMS JOHN
IPC: G07F17/32
Filed: 2003-08-13
Abstract: A gaming machine (10) includes a chamber-defining portion that defines a chamber (62). A panel (58) carrying gaming machine artwork (28) is arranged on one side of the chamber (62). A light diffusing element (60) is arranged on an opposed side of the chamber (62) in spaced relationship relative to the panel (62). A gaming machine illuminating arrangement (50) is arranged in the chamber between the panel (58) and the light diffusing element (60).
Patent NZ-528150-A (NZ)
Title: Combinations of aldose reductase inhibitors and cyclooxygenase-2 inhibitors
Inventor: MYLARI BANAVARA LAKSHMAN
IPC: A61K45/00
Filed: 2002-02-25
Abstract: Pharmaceutical compositions and kits comprising pyridazinone compounds and cyclooxygenase-2 inhibitors are disclosed. Therapeutic methods of treatment or prevention of certain complications arising from diabetes mellitus in mammals and therapeutic methods of treatment or prevention of cardiac tissue ischemia in mammals are also described.
Patent NZ-537472-A (NZ)
Title: Wire-strike system
Inventor: SMITH DEAN CHARLES
Filed: 2004-12-23
Abstract: A system for severing cables when struck by an aircraft is disclosed. The system 1 includes elongated strips 3 that consist of a pair of electrodes mounted on an aircraft 2. The electrodes are electrically insulated from each other and are connected to a power source 11 capable of generating a high current discharge when a short circuit condition occurs by contact with an external cable. This results in the severing of the cable, preventing the aircraft from crashing.
Patent NZ-537882-A (NZ)
Title: Biaryl diazabicycloalkane amides as nicotinic acetylcholine agonists
Inventor: ERNST GLEN
IPC: A61K31/551
Filed: 2003-08-13
Abstract: Disclosed is a compound of formula I wherein: A is a moiety of formula II: D is oxygen or sulfur; E is a single bond, oxygen, sulfur or NR3; Ar1 is a 5-or 6-membered aromatic heterocyclic ring having 1, 2 or 3 heteroatoms selected from nitrogen, oxygen or sulfur where not more than one of said heteroatoms is oxygen or sulfur, or Ar1 is phenyl; Ar2 is a 5-or 6-membered aromatic heterocyclic ring having 1, 2 or 3 heteroatoms selected from nitrogen, oxygen or sulfur where not more than one of said heteroatoms is oxygen or sulfur, or Ar2 is a phenyl, or Ar2 is an 8- or 9-, or 10-membered fused aromatic carbocyclic ring or fused aromatic heterocyclic ring having 1, 2 or 3 heteroatoms selected from nitrogen, oxygen or sulfur where not more than one of said heteroatoms is oxygen or sulfur, or an 8- or 9-, or 10-membered aromatic carbocyclic ring; The rings Ar1 and Ar2 are substituted with 0, 1, 2, or 3 substituents selected from: halogen, C1-4alkyl, C2-4alkenyl, C2-4alkynyl, CN, NO2, CF3NR1R2, CH2NR1R2, CH2OR2 or CO2R3; And the rest of the substituents are described in the specification. Also disclosed is the use of the above compound in the manufacture of a medicament for the treatment of a number of diseases or conditions associated with nicotinic acetylcholine receptors (nAChRs).
Patent NZ-540788-A (NZ)
Title: Method for controlling a selected deposition of a polymer on an industrial fabric and industrial fabric
Inventor: DAVENPORT FRANCIS L
IPC: D04H3/12
Filed: 2003-11-06
Abstract: Disclosed is a method for manufacturing a papermaker's or industrial fabric requires the application of a polymeric resin material onto preselected locations on a bare substrate using a piezojet array which deposits the polymeric resin material in droplets having an average diameter of 10 (10 microns) or more. The preselected locations, for example, may be knuckles formed by the interweaving of the yarns making up the fabric or interstices between the yarns. The purpose of such precise application of the resin is to control functional properties of the fabric, such as permeability and abrasion resistance. The polymeric resin material is set by means appropriate to its composition, and, optionally, may be abraded to provide the polymeric resin material above the surface plane of the base substrate with a uniform thickness.
Patent NZ-542059-A (NZ)
Title: Therapeutic compositions comprising an aryl sulphonate such as suramin, for the treatment of a pathological condition or event of the systemic vasculature resulting form the producation of reactive oxygen species.
Inventor: DUSTING GREGORY JAMES
IPC: A61P35/00
Filed: 2004-02-27
Abstract: Discloses the use of an aryl sulphonate compound such as suramin, for the manufacture of a medicament for the treatment or prophylaxis of a pathological condition or event of the systemic vasculature resulting from the production of reactive oxygen species in a subject, wherein the aryl sulphonate inhibits an extracellularly exposed form of a Nox4 component of an NADPH oxidise.
Patent NZ-543484-A (NZ)
Title: Automatic clothes dryer controlled by adjustment of airflow to attain a desired airflow rate
Inventor: CAROW JAMES P
Filed: 2005-11-08
Abstract: Automatic clothes dryer operation is controlled by estimating the air flow and comparing it with a desired flow, then adjusting the motor speed in response to the comparison such that the air flow approaches the desired flow.
Patent NZ-544890-A (NZ)
Title: Palatable ductile chewable veterinary composition
Inventor: ISELE UTE
IPC: A23K20/195
Filed: 2004-07-29
Abstract: Disclosed is a highly palatable ductile chewable veterinary composition comprising (A) an effective amount of one or more ingredients that are active against animal pests, pathogens or animal diseases; (B) meat flavouring; (C) partially gelatinized starch; (D) a softener; and (E) up to 9% water.
Patent NZ-545008-A (NZ)
Title: Reciprocating slat conveyor with v-slats
Inventor: FOSTER RAYMOND KEITH
Filed: 2006-01-30
Abstract: A reciprocating slat conveyor, comprising: framework providing a support for fixed and movable conveyor slats, said framework defining a window sized to receive three transverse drive members and allow said drive members to reciprocate in the window longitudinally of the conveyor; three transverse drive members in said window; laterally spaced apart fixed slats, extending longitudinally of the conveyor and supported on the framework both forwardly and rearwardly of the window; said fixed slats extending longitudinally over the window; said fixed slats supporting elongated bearings that extend length wise of the slats substantially throughout the full length of the slats; laterally spaced apart movable conveyor slats extending longitudinally of the conveyor between the fixed slats, said movable conveyor slats being divided into sets, one set for each transverse drive member; wherein each set of movable conveyor slats is connected to a related one of the transverse drive members, so that each set of slats will move with its transverse drive member; said movable slats having portions that rest on the bearings so that during longitudinal movement of the movable slats said slats will move on the bearings; wherein the fixed slats are longitudinal beams having laterally spaced apart side parts and a top wall connected to the side walls; wherein the fixed conveyor slats are box beams having spaced apart side walls, a top and a bottom spaced below the top and extending between the side walls; and wherein the movable conveyor slats comprise longitudinal box beams that are disposed between the fixed conveyor slats, said box beams having spaced apart sidewalls, a top and a bottom spaced below the top and extending between the sidewalls.
Patent NZ-546340-A (NZ)
Title: Compositions for controlling parasites comprising a combination of abamectin and ivermectin
Inventor: DA COSTA ALVIMAR JOSE
IPC: A01N43/90
Filed: 2004-10-15
Abstract: Disclosed is a composition for controlling parasites in and on animals, which comprises in a controlled release vehicle a combination of ivermectin and abamectin, wherein the total percentage w/v of ivermectin and abamectin equals or exceeds 3% w/v and the concentration of ivermectin is higher than the concentration of abamectin. Also disclosed is the use of the above composition for the treatment of ecto- and endo-parasitic infections.
Patent NZ-546432-A (NZ)
Title: Medical device for analyte monitoring and drug delivery
Inventor: HOLMES ELIZABETH A
IPC: A61M5/145
Filed: 2004-09-10
Abstract: A medical device capable of detecting an analyte in a bodily fluid is disclosed. The device comprises of: at least one microneedle capable of obtaining a sample of a bodily fluid; a buffer reservoir; a microchannel; a microarray scanning device; and an interface device. The microchannel has at least a first inlet, a second inlet, and a microarray attached onto the microchannel, where the microarray comprising at least one bioactive agent. The first inlet is in fluid communication with the microneedle and channels a flow of bodily fluid into the microchannel. The second inlet channels a flow of buffer from the buffer reservoir into the microchannel, such that the analyte in the bodily fluid diffuses into the flow of buffer to effect an interaction between the bioactive agent and the analyte. The microarray scanning device detects the interaction between the bioactive agent and the analyte in a bodily fluid.The interface device capable of facilitating communications between the microarray scanning device and a biometric recognition device.