baber/WOPTO huggingface dataset:
Patent IE-881523-L (IE)
Title: A method for detecting the antiaggregatory effect of¹vasoactive substances, specifically of inhibitors of¹phosphodiesterase and/or cyclooxygenase
IPC: C12Q1/34
Filed: 1988-05-20
Abstract: The anti-aggregatory activity of phosphodiesterase inhibitors (A) and/or of cyclooxygenase inhibitors (B) is detected outside the human or animal body by
 removing blood,
 adding (A) and/or (B) to the removed blood - if not already present therein in unchanged or in metabolised form as a consequence of a previous administration,
 where appropriate removing the erythrocytes and leucocytes, and
 initiating - preferably by adding an aggregation inducer - and measuring the platelet aggregation,
 where (A) - if only (B) has been administered or added up till then - is then added either before or, at the latest, on initiation of the platelet aggregation,
 or (B)- if only (A) has been administered or added up till then - is then added,
 and at least one prostaglandin (C) is added,
 so that the initiation and measurement of the platelet aggregation takes place in the presence of the triple combination of (A), (B), each in unchanged or in metabolised form, and (C). 
<??>Suitable as (A) are preferably compounds with a xanthine or pyrimidopyrimidine structure and as (B) is preferably O-acetylsalicylic acid. The method replaces elaborate and complicated tests on the human and animal body.
Patent IE-891591-L (IE)
Title: Antibiotic
IPC: C07K7/08
Filed: 1989-05-17
Abstract: A peptide antibiotic having the structure which can be used to combat bacteria and to treat bacterial infections.
Patent IE-802135-L (IE)
Title: Pyrazolobenzodiazepines
IPC: A61P25/20
Filed: 1980-10-15
Abstract: Compounds are described of the formula <IMAGE> or an acid addition salt thereof; in which R1, R2, R3 and R4 independently represent hydrogen, C1-4 alkyl, C2-4 alkenyl, C3-7 cycloalkyl, C3-7 cycloalkyl C1-4 alkyl, halogen, C1-4 haloalkyl, C1-4 alkanoyl, nitro, amino, C2-4 acylamino, cyano, hydroxyl, C1-4 alkoxy, C1-4 alkylthio, C1-4 haloalkoxy or a group of the formula -SO2N(R8)2, -SO2R8 or -SO3R8 where R8 is C1-4 alkyl, C1-4 haloalkyl or optionally substituted phenyl; in which R5 is a group of the formula <IMAGE> where R9 is hydrogen, C1-4 alkyl, C3-7 cycloalkyl, C3-7 cycloalkyl C1-4 alkyl, C1-4 haloalkyl, C2-4 alkenyl, C1-4 alkanoyl, benzyl, cyano or optionally substituted phenyl, where R10 is hydrogen, C1-4 alkyl or optionally substituted phenyl and where n is 0 or 1; in which R6 is hydrogen, C1-10 alkyl, C3-7 cycloalkyl, C3-7 cycloalkyl C1-4 alkyl, C1-4 haloalkyl, benzyl, C1-6 alkanoyl, C1-4 carbalkoxy or benzoyl; and in which R7 is one of the values of R6 or halogen, nitro, cyano, amino or C1-4 acylamino. The compounds are active as pharmaceuticals and particularly in the treatment of disorders of the central nervous system. Intermediate compounds in which R5 is thiol, hydroxy, or amino are also described.
[US4404137A]
Patent IE-872507-L (IE)
Title: Penicillium transformants
IPC: C12N15/31
Filed: 1987-09-16
Abstract: Novel and efficient methods for preparing Penicillium transformants are provided employing DNA constructs having a structural gene complementing an auxotrophic host and, preferably, the ans gene. Conditions are provided for frequency of transformation.
Patent IE-862762-L (IE)
Title: Chlorination of carbohydrates and other alcohols
IPC: C07B39/00
Filed: 1986-10-20
Abstract: Chlorination of carbohydrates and alcohols utilizing a chlorinating reagent selected from triphenylphosphine oxide/thionyl chloride, thiphenylphosphine oxide/phosgene, triphenylphosphine sulfide/thionyl chloride and triphenylphosphine sulfide/phosgene.
[US4783526A]
Patent IE-44051-L (IE)
Title: Marine riser system
IPC: E21B7/128
Filed: 1976-12-30
Abstract: A dual marine riser for use in drilling deepwater oil and gas wells from a floating vessel, the marine riser incorporating concentric inner and outer risers, the outer riser being provided with one or more remotely-actuatable valves adapted to bring the annular space between the risers into communication with surrounding sea water in order to equalize pressures over the wall of the outer riser when the inner riser has been installed.
[US4059148A]
Patent IE-873089-L (IE)
Title: Pyrrolo-benzimidazoles
IPC: A61P9/00
Filed: 1987-11-17
Abstract: Pyrrolobenzimidazoles of the formula <IMAGE> in which A and B together with the two intermediate carbon atoms represent an imidazo group of the formula <IMAGE> in which R1 represents a hydrogen atom or an alkyl group which is optionally substituted by a phenyl group and R2 represents a hydrogen atom, an alkyl group which is optionally substituted by a phenyl, pyridyl or thienyl group, a vinylene group which is substituted at the end by a phenyl or pyridyl group, a phenyl group which is optionally substituted by a halogen atom, or a hydroxyl, alkoxy, mercapto, alkylmercapto, alkylsulphinyl, alkylsulphonyl, cyano, amino, alkylamino, dialkylamino, alkanoylamino or nitro group, it being possible for a hydroxyphenyl group to be substituted additionally by one or two alkyl groups or an aminophenyl group to be substituted by one or two halogen atoms, a phenyl group disubstituted by halogen atoms, or hydroxyl, alkoxy, mercapto, alkylmercapto, alkylsulphinyl or alkylsulphonyl groups, it being possible for the substituents of the phenyl ring to be identical or different, a 5- or 6-membered heteroaromatic ring bonded via a carbon atom and which contains an oxygen, sulphur or nitrogen atom, two or three nitrogen atoms or a nitrogen atom and an oxygen or sulphur atom, to which one or two 1,4-butadienyl groups can be additionally bonded via two adjacent carbon atoms, where in this case the bonding can also take place via a fused-on phenyl ring and in the case of the pyridines these can additionally be substituted by an amino, alkylamino, dialkylamino, alkanoylamino or morpholino group or by two halogen atoms or by a halogen atom and an amino or morpholino group and in the case of the quinolines can be additionally mono- or disubstituted by a halogen atom, or an alkoxy or phenyl group, it being possible for the substituents to be identical or different, a 5- to 7-membered saturated imino-, N-alkylimino- or N-alkanoylimino-alkylene ring bonded via a carbon atom, or a 1,2,3,4-tetrahydroquinolyl or 5,6,7,8-tetrahydroquinolyl group, R3 represents an alkyl group which is optionally substituted by a phenyl group, an alkyl group or an alkyl group which is substituted from position 2 by a hydroxyl, alkoxy or pyridinium group, R4 and R5, which can be identical or different, represent hydrogen atoms, alkyl groups or cycloalkyl groups, and their acid addition salts, for pharmaceutical use in particular their physiologically tolerable acid addition salts with inorganic or organic acids, which have useful pharmacological properties, in particular a slight influence on the blood pressure, a positive inotropic effect and an antithrombotic effect. The novel compounds can be prepared by methods known per se.
[EP0268178A1]
Patent NO-821833-L (NO)
Inventor: FISCHER RICHARD
IPC: A47F1/04
Filed: 1982-06-02
Abstract: 1. Storage system consisting of disposable plastic containers which are sealed by means of a cover after filling and possess, at least on two opposing sides, a projection (11) which extends forward beyond the actual container cross-section, and of a shelving unit (20) which is provided, on its mutually facing inner sides, with horizontal support surfaces (23) arranged in pairs at a distance one above another, and having a dimension of the disposable container (10, 22) in the region of the projection (11) which is such that the disposable container (10, 22) can be pushed into the shelving unit (20) by means of the projection (11) in the manner of a drawer, resting on the bearing surfaces (23), and is suspended in place by its projection (11), characterized in that the projection (11) is designed as an outwardly bent part area of the side walls at the opening edge or edges of the disposable container (10, 22) and in that the horizontal support surfaces (23) arranged in pairs on the mutually facing inner walls are arranged at the same height in each case.
Patent NO-841992-L (NO)
Inventor: SHAH DHIREN
IPC: A61K9/22
Filed: 1984-05-18
Abstract: Compression gradient tablets are described which provide for controlled release of active ingredient.
Patent NO-853681-L (NO)
Title: Isolasjonspanel for termisk og akustisk isolering.
Inventor: JAHR KNUTH
IPC: F01D25/30
Filed: 1985-09-20
Abstract: Termisk og akustisk Isolasjonspanel for Innvendig og utvendig Isolering av røkgasskanaler og gassturbin eksoskanaler, bygget opp med, ekspanderende kjeramlske fIberblokker med stiende fibre (2), beskyttet med Inconel-forsterket, vevet kjeramlsk duk (3) og med finmasket (70 mesh) vevet duk 1 materialet AISI 316 (4) og med perforert plate (40S lysJpnlng) 1 materiale AISI 409.(5)
Patent NO-874231-L (NO)
Title: Rensing av rekombinant tumornekrosefaktor.
Inventor: NELLES LYNN PATRICK
IPC: C12P21/00
Filed: 1987-10-09
Abstract: Fremgangsmåte til rensing av rekombinant tumornekrosefaktor fra kulturer av mikroorganismer transformert med vektorer som koder for produksjonen av tumornekrosefaktor. En sekvens av berøringstrinn inn-går i fremgangsmåten, slik at utløps-strømmen fra det første berøringstrinn kan bringes i kontakt direkte med det berøringsmateriale som benyttes i det andre trinn, og på samme måte, utløps-strømmen fra det andre beraringstrinn kan bringes i kontakt direkte med det berøringsmateriale som benyttes i det tredje berøringstrinn. I en foretrukket utførelsesform kan tumornekrosefaktor-holdig fermenteringsvæske i betydelig grad renses ved en enkelt passasje gjennom et flerkomponent-kromatografisystem, dvs. at de farste, andre og tredje berøringsmaterialer er hver pakket i en kolonnekonfigurasjon, idet TNF-holdig væske føres direkte gjennom kolonne-sekvensen. Behovet for mellomliggende isolering, konsentrering, rekondi-sjonering og lignende av de tumornekrosefaktor-holdige fraksjoner unngås derfor ved utførelse av oppfinnelsen.
Patent NO-882905-L (NO)
Inventor: REYNOLDS BRUCE A
IPC: B41F13/60
Filed: 1988-06-29
Abstract: The invention provides a cutoff control system having a capture range equal to the length of the image (signature) which is highly tolerant of spurious transitions, such as lateral shifting and instantaneous interruptions of the web. A highly pipelined hardware correlation unit, cooperating with several high speed RAM devices having independent address generators, is used to cross-correlate new patterns with a reference pattern. An illustrated system for relating a cyclical machine operation to the position of images on a web includes position adjustment means (24,30,84) responsive to control signals for varying the effective position of the machine operation along the moving web, means (34,40,50) for generating image signatures indicative of the image at respective sampling intervals during the matching operation cycle for respective machine cycles, means (56,58,68,72) for selectively generating reference pattern indicia from a first image signature and for selectively generating comparative indicia from a successive image signature, means (71) for generating correlation cooeficients in accordance with the differences between the reference pattern and shifted versions of the comparative indicia, means (68,69,70) for processing the correlation coefficients to determine which of the comparative indicia produced the largest correlation coeficient and generating an indicating signal in response thereto, and means (80) for generating the control signals to the position adjustment means in accordance with the indicating signal.
Patent NO-892807-L (NO)
Inventor: MEYER JEAN-LUC
IPC: B22D11/14
Filed: 1989-07-06
Abstract: A method is disclosed for making thixotropic metal products by continuous casting by pouring liquid metal into a mold with a movable end and having upstream and downstream portions. The upstream portion has a wall made of a heat insulating material at least at its inner surface to form a hot zone, and the downstream portion has a wall made at least partially of a heat conducting material to form a cold zone. A movement is imparted to the solidifying liquid to cause circulation between the cold zone and the hot zone in order to bring about surface remelting of crystals formed in the cold zone and degeneration of dendrites.
Patent NO-902534-L (NO)
Title: Forankringsring.
Inventor: SEATON RUSSEL
IPC: E21B33/04
Filed: 1990-06-07
Abstract: En landering (60, 96) for bruk ved stabling av hengere (14, 40, 80) i et brønnhodehus (10). Hver landering kan være forbun- det ned en nedadvendt landingsskulder på et lag på en slik måte at relativ sidebevegelse muliggjøres mellom ringen og laget. Den nedre flate på hver ring kan være konisk for anlegg mot en motsvarende formet flate på den øvre flate til en annen henger som den skal anbringes på. Arrangementet virker til å innrette et lag sideveis i huset uavhengig av innrettingen til et lag som det er anbragt på.
Patent NO-902586-L (NO)
Inventor: BEWLEY DAVID ROBERT
IPC: A23B4/08
Filed: 1990-06-11
Abstract: A method of processing meat characterized in that the meat is introduced into a mobile cooking vessel, the vessel is sealed and adjusted to super-atmospheric pressure, a stock liquor is passed through a heat exchanger to raise its temperature to at least 60 DEG C and circulated through the vessel and heat exchanger for a period of time sufficient to heat up and cook the meat, substantially immediately after which the circulating stock liquor is cooled by the same heat exchanger to a temperature suitable for cooling the meat to 15 DEG C or below within a maximum time of 45 minutes.
Patent NO-905221-L (NO)
Title: Steriliseringsblandinger og anvendelse derav.
Inventor: LAWSON TREVOR JOHN
IPC: A01N25/18
Filed: 1990-12-03
Abstract: Preparat som gir forlenget fri-givelse av et luftbåret desinfeksjons-middel, spesielt svovéldioksid, i nær-vær av fuktighet. Preparatet inneholder et middel som vil frigi svoveldioksid ved kontakt med vann, en moderator for å bremse frigivelsen av svoveldioksid, et fortykningsmiddel og vann. Det er hensiktsmessig å pakke preparatet i en lukket beholder som, når den er åpnet, kan plasseres i en avhendingsbeholder for sanitærbandasjer eller kirurgiske bandasjer for å sterilisere disse i avhendingsbeholderen.
Patent NO-911317-L (NO)
Inventor: BASTIOLI CATIA
IPC: C08L101/16
Filed: 1991-04-04
Abstract: PCT No. PCT/EP90/01253 Sec. 371 Date Mar. 27, 1991 Sec. 102(e) Date Mar. 27, 1991 PCT Filed Aug. 1, 1990 PCT Pub. No. WO91/02024 PCT Pub. Date Feb. 21, 1991.Polymer compositions useful for the production of articles of biodegradable plastics material with improved biodegradability include destructed starch and a polymer selected from the group consisting of ethylene-vinyl alcohol, polyvinyl alcohol and mixtures thereof wherein at least a portion of the said polymer is modified by the substitution of from 0.1 to 5 molar % of the functional alcohol groups in the polymer chain by X groups in which X is an oxo or an alkyl carbonyl group in which the alkyl group contains from 1 to 4 carbon atoms.
Patent NO-913080-L (NO)
Inventor: RAITH ALEX KRISTER
IPC: H04W84/16
Filed: 1991-08-08
Abstract: The invention relates to a communication method and a combination of a switched telecommunication network and connected to the network, a first automatic branch exchange or residential equipment for a subscriber, a second automatic branch exchange or residential equipment for a subscriber, possibly also a telepoint, and a portable radio terminal constituting part of a residential equipment or an extension to an automatic branch exchange, the portable radio terminal when served by a radio transceiver other than its residential or exchange radio transceiver uses the branch exchange or telepoint and the network for calling its residential base radio station or branch exchange and reporting serving branch exchange or telepoint or a temporary number to a location store, calls to the portable radio terminal thereafter being transferred by the residential equipment or branch exchange through the network to the branch exchande or telepoint in accordance with information in the location store, whereby the portable radio terminal may call and be called through the network and proximate branch exchange or telepoint.
Patent NO-921626-L (NO)
Title: Fortrinnsvis forsterket, fingring-indikerende plastlukke
Inventor: TRUMP HUBERT DALE
IPC: B65D/
Filed: 1992-04-27
Abstract: Et fingring-indikerende plastlukke (10) omfatter et forseglingsbånd (24) som er i det minste delvis losbart forbundet med et skjørtparti (16) på lukket (10) ved hjelp av en skjor forbindelse. Den skjøre forbindelse omfatter et antall omkretsmessig fordelte, skjøre broer (34) som brister ved fjerning av lukket. (10) fra en tilhørende beholder (C) for å gi visuelt tydelig bevis på åpning. For å lette hurtig-påføring av lukket (10) på en beholder (C), er ett eller flere områder av den skjøre forbindelse fortrinnsvis for- sterket ved anordning av forholdsvis forsterkete, skjøre broer (34A, 34B). Minst en av de forsterkete broer er beliggende generelt diametralt motsatt inn- ledningspartiet til lukkets (10) innvendige gjenge- formasjon (18).
Patent NO-930500-L (NO)
Inventor: FERRE JOSE MANUEL RODRIGUEZ
IPC: A63H33/10
Filed: 1993-02-12
Abstract: The articulated structure for dolls or puppet bodies of the invention consists of a structure or skeleton-like framework in which the various elements and members which comprise it are connected with one another at their ends by means of link connections (8,9) which in combination with the structure of the referenced ends constitute ball and socket articulations. The link connections are formed by two spheres 8a connected by a radial appendix 8b, over which is injected the integrating material making up the semispherical catches 9, constructed in the ends of the elements or members of the skeleton-like framework. The improvements are applicable in the manfuacture of articulated structures for dolls which permit stable and voluntary positioning of their members or connecting parts. <IMAGE>
Patent NO-943825-L (NO)
Inventor: BERGLUND RICHARD ALAN
IPC: C07F9/06
Filed: 1994-10-10
Abstract: Prepn. of S-(+)-N,N-dimethyl-3-(1-naphthyloxy)-3-(2- thienyl)-propanamine (I) comprises reacting (S)-(-)-N,N- dimethyl-3-(2-thienyl)-3-hydroxy-propanamine (II) with sodium hydride, potassium benzoate or acetate and 1-fluoro-naphthalene (III) in an organic solvent. (II) and NaH are dissolved in the solvent, the potassium cpd. is added with stirring, then (III) is added with stirring. (I) is isolated as the phosphoric acid salt. Typically the solvent is DMSO, the use amt. of NaH is 1 equiv/equiv. (II), the use amt. of potassium cpd. is 0.05-1 equiv./equiv. (II) and stirring is at 10-35 [deg] C for 5-60 min. Use amt. of (III) is 1-25% excess and stirring is at 40-75 [deg] C for 1.5-4 hrs.
Patent NO-944642-L (NO)
Title: Fremgangsmåte for fremskynding av oppvarming av faststoffkatalysatorer ved tilförsel av hjelpe-energi
Inventor: ENGLER BERND
IPC: B01D53/94
Filed: 1994-12-02
Abstract: Det blir beskrevet en fremgangsmåte for påskyndlng av oppvarming av en faststoffkatalysator til starttempera- turen for den katalytiske reaksjonen ved tilførsel av hjelpe-energi fra eksterne energikilder l løpet av en begrenset aktlverlngstld, hvorved faststoffkatalysa- toren kan foreligge som monolitt eller l gittergodsform og har en definert tllstrømnlngsoverflate for reak- sjonsmedlene. HJelpe-energien blir tilført på en eller flere isolerte deloverflater av tilstrømningsoverflåten til katalysatoren. Derigjennom kan energibehovet for starting av katalysatoren bil holdt lavt.
Patent NO-962652-L (NO)
Title: Langtidsvirkende insektmidler samt anvendelse derav
Inventor: TUCCI RAYMOND J
IPC: D06M15/643
Filed: 1996-06-21
Abstract: Saktefrigjørende insektsfrastøtende formuleringer omfattende det insektsfrastøtende middel N,N'-di- etyl-m-toluamid er beskrevet. Det er også beskrevet tøysubstrater som er behandlet med formuleringene ifølge oppfinnelsen. Fremgangsmåter for å fremstille formuleringene for å behandle tøysubstratene og for å frastøte insekter ved å bruke disse er beskrevet.
Patent NO-973652-L (NO)
Inventor: BERNSTEIN PETER ROBERT
IPC: A61K31/47
Filed: 1997-08-08
Abstract: Compounds of formula (I), wherein Q<1>, Q<2>, Q<3> and Q<4> have any of the meanings given in the specification, their N-oxided, and their pharmaceutically acceptable salts are nonpeptide antagonists of SP and NKA, useful for the treatment of asthma, etc. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of formula (I) and intermediates.
Patent NO-980699-L (NO)
Inventor: EMRICH THOMAS
IPC: C12N15/09
Filed: 1998-02-19
Abstract: The invention concerns a method for the detection of telomerase activity wherein(a) a sample to be tested is provided,(b) a first primer suitable as a telomerase substrate and nucleoside triphosphates are added and the reaction mixture is incubated under conditions under which a primer extension by the telomerase can take place,(c) an amplification of the extension product produced by the telomerase is carried out,(d) the amplification product produced in step (c) is immobilized on a solid phase and(e) the immobilized amplification product is detected qualitatively or/and quantitatively. Furthermore the invention concerns a suitable reagent kit for carrying out the method.
Patent NO-981304-L (NO)
Inventor: HEETHAAR ROBERT MARTIN
IPC: A61B5/05
Filed: 1998-03-23
Abstract: The invention relates to an apparatus for the in vivo non-invasive measurement of a biological parameter concerning a bodily fluid of a person or animal in accordance with a calculation model, wherein the apparatus is provided with connections for at least two pairs of electrodes (2-5, 8-11) to be placed on the skin of a part of the body, a pair of input electrodes (2, 3, 8, 9) for feeding a measuring alternating current to the part of the body and a measuring pair of electrodes (4, 5, 10, 11) for measuring the voltage at the measuring pair of electrodes, comprising a current source (7, 12) providing the measuring alternating current, a transformer (31) for the transformation of the measuring voltage into a bio-impedance signal, being a measure of the bio-impedance of the part of the body, and means for the generation of signals which form a measure for further parameters to be determined with the aid of the calculating model, said signals encompassing a signal forming a measure for the time derivative of the bio-impedance signal. The current source (7, 12) has a minimal radiation configuration and is suitable for generating a measuring current having a constant amplitude on at least two frequencies, a low frequency and a high frequency, in a frequency range of up to about 2000 kHz.
Patent SE-0000647-L (SE)
Inventor: SUNDSTROEM BENGT
IPC: G06F17/30
Filed: 2000-02-29
Abstract: A method is universally applicable, enabling storing all types of data and structures of data. The method is based on structure elements being self-contained information carriers, represented by pairs of concept and concept value and associated context information. Using the method, data can be organised in hierarchies of structure elements with arbitrary depth and complexity. In spite of its simplicity, the method can reflect connection, context and meaning, however complex, irrespective of types of data and how complex the relations between data may be. Hence, the method represents a fundamental framework for standardised physical data storage of all types of data.