baber/WOPTO huggingface dataset:
Patent CA-2427105-A1 (CA)
Inventor: KAN YUSUKE
IPC: H01M50/59
Filed: 2003-04-28
Abstract: An apparatus and method for preventing an interruption of electrical power to a portable electronic device, such as, for example, a call device, supplied by an internal battery when the portable electronic device is dropped or subjected to an external shock. A battery cover seals a battery compartment in which a negative battery terminal and a positive battery terminal, of a battery, are in contact with a respective compressible contact terminal and a fixed terminal. A battery fixing base plate, attached to an inner surface of the battery cover, includes a set flange that is inserted between a battery compartment wall to which one contact terminal is attached and an associated battery terminal in contact with the one contact terminal, thus providing a mechanism that prevents a longitudinal movement of the battery in the battery compartment.
Patent CA-2427257-A1 (CA)
Title: Expression vectors able to elicit improved immune response and methods of using same
Inventor: PAVLAKIS GEORGE N
IPC: A61P43/00
Filed: 2001-11-01
Abstract: The invention relates to nucleic acids (such as DNA immunization plasmids), encoding fusion proteins containing a destabilizing amino acid sequence attached to an amino acid sequence of interest, in which the immunogenicity of the amino acid sequence of interest is increased by the presence of the destabilizing amino acid sequence. The invention also relates to nucleic acids encoding secreted fusion proteins, such as those containing chemokines or cytokines, and an attached amino acid sequence of interest, in which the immunogenicity of the amino acid sequence of interest is increased as a result of being attached to the secretory sequence. The invention also relates methods of increasing the immunogenicity of the encoded proteins for use as vaccines or in gene therapy.
Patent CA-2428504-A1 (CA)
Inventor: DOCKRILL MARK
IPC: G01N21/00
Filed: 2003-05-13
Abstract: A device and method for sampling a fluid from a container. The device may be used in hospital/clinical diagnostic applications as a point-of-care single-use disposable medical device. The method includes sampling and analysing with the device a fluid sample, such as a biological fluid, from a container.
Patent CA-2429268-A1 (CA)
Title: 2-butyl-3-(4-[3(dibutylamino)propoxy]benzoyl)-5-nitro-benzofuranhydrochloride and its preparation
Inventor: BIARD MICHEL
IPC: C07C217/22
Filed: 2001-12-10
Abstract: The invention concerns 2-butyl-3-(4-[3(dibutylamino)propoxy]benzoyl)-5-nitro-benzofuran hydrochloride, its preparation and its use as synthesis intermediate in particular for preparing 2-butyl-3-(4-[3-(dibutylamino)propoxy]benzoyl)-5-nitro-benzofuran which is itself intermediate for dronedarone.
Patent CA-2430119-A1 (CA)
Title: External processor for a distributed network access system
Inventor: THOMAS HOWARD LEE
IPC: H04L12/56
Filed: 2001-11-28
Abstract: An external processor (42) for a network access system having a programmable access device (40a, 40b) includes a service controller (120a, 120b) that provides at least one service for network traffic, a message processor (122) that processes network messages for service processing by the service controller (120a, 120b), and a programmable access device controller (124) that programs the programmable access device (40a, 40b) in response to service controller processing. It is advantageous for the external processor (42) to include primary (120a) and secondary service controllers (120b) for a particular service so that, if the primary service controller (120a) fails, the secondary service controller (120b) can provide the particular service for message received from the programmable access device (40a, 40b). In preferred embodiments, the service controller further includes a reporting processor (126) that provides an interface through which reporting messages received from the programmable access device (40a, 40b) can be communicated to the service controller (120a, 120b) and a signaling controller (128a, 128b) that transmits signals to configure network hardware to establish requested network connections. The external processor (42) preferably further supports a service policy interface (56) through which the service controller (120a, 120b) can request policy decisions from a possibly remote policy server.
Patent CA-2431402-A1 (CA)
Title: Decontaminated fluids and biocidal liquids
Inventor: MACGREGOR SCOTT JOHN
IPC: C02F1/78
Filed: 2001-12-13
Abstract: There is disclosed a method for the purification or decontaminating of contaminated a gased and liquids and for the production of biocidal liquids that have a finite activity period. The method comprising the steps of aerating or sparging a liquid (17) with a gas such as to provide a suspensio n of bubbles (17A) within the body of the liquid, and then subjecting the aerated or sparged liquid to a pulsed electrical field having a magnitude sufficiently high to create ionisation activity in the gas bubbles (17A).</S DOAB>
Patent CA-2433583-A1 (CA)
Title: Composition of insulin for nasal administration
Inventor: OKI TOSHIKAZU
IPC: A61P3/10
Filed: 2002-07-03
Abstract: Granular compositions containing insulin for nasal administration which comprise as a carrier aggregated crystalline cellulose having a specific grain distribution. Nasal administration of such a granular composition makes it possible to efficiently elevate blood insulin concentration.
Patent CA-2434456-A1 (CA)
Inventor: AHLQUIST PAUL G
IPC: A61K35/12
Filed: 2001-12-27
Abstract: Cette invention concerne un agent antiviral renfermant un gèneMAB1, MAB2, MAB3 ou OLE1 altéré, des homologues de ces gènes ou des gènes apparentés. Selon un autre mode de réalisation, l'invention concerne une méthode consistant à créer un organisme résistant au virus, qui comprend un agent antiviral pris dans les gènes MAB1, MAB2, MAB3 ou OLE1 altérés, des homologues de ces gènes et des combinaisons desdits gènes et homologues.
Patent CA-2438849-A1 (CA)
Title: Compounds and compositions for delivering active agents
Inventor: WANG NAI FANG
IPC: A61K/
Filed: 2002-03-01
Abstract: Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well.
Patent CA-2439310-A1 (CA)
Title: Process for preparing fluconazole and its crystal modifications
Inventor: NAGYNE BAGDY JUDIT
IPC: C07D249/08
Filed: 2001-03-23
Abstract: The invention relates to a process for preparing of fluoconazole of formula (I) and its crystal modifications. The process is as follows; a) hydrolyzing a silyl ether derivative of formula (II) wherein the meaning of R2 is hydrogen, or a C1-C10 alkyl or phenyl group, R3 and R4 independently of each other are a C1-C10alkyl or phenyl group -at a pH preferably either below 3 or above 8 in an aqueous solution, cooling the obtained reaction mixture and isolating the precipitated fluconazole monohydrate, dissolving the fluconazole monohydrate in a C1-C4 straight or branched chain alcohol at boiling temperature and cooling the solution slowly, preferably with a speed of 5-15 ~C/h to obtain the crystal modification II of fluconazole, or fast, preferably with a speed of 35-65 ~C/h to obtain the crystal modification I of fluconazole and in both cases isolating the precipitated crystals and rying, or b) dissolving fluconazole monohydrate in C1-C4 straigth or branched chain alcohol at boiling temperature and cooling the solution slowly, preferably with a speed of 5-15 ~C/h to obtain the crystal modification II of fluconazole, or fast, preferably with a speed of 35-65 ~C/h to obtain the crystal modification I of fluconazole and in both cases isolating the precipitated crystals and drying, or c) drying slowly fluconazole monohydrate after seeding preferably with seeding crystals of crystal modification II at 30-70 ~C, preferably in vacuum to obtain the crystal modification II of fluconazole, or d) drying fast fluconazole monohydrate after seeding preferably with seeding crystals of crystal modification I at 80 ~C, to obtain the crystal modification I of fluconazole.
Patent CA-2442289-A1 (CA)
Inventor: PARK CHEOL-WON
IPC: C07D333/38
Filed: 2002-03-15
Abstract: La présente invention concerne un nouveau procédé de préparation par réaction en une seule étape d'un composé représenté par la formule (7), qui est un intermédiaire important d'un inhibiteur de la thrombine oral. L'invention permet de produire l'intermédiaire d'inhibiteur de la thrombine précité avec un rendement élevé.
Patent CA-2442325-A1 (CA)
Inventor: GREENWOOD DAVID ROGER
IPC: A23L1/305
Filed: 2002-03-27
Abstract: This invention provides a protein which exhibits metal ion binding activity.  The protein can be readily extracted from the pacific oyster, Crassostrea gigas and can be formulated into bioremediation compositions, foodstuffs, nutraceuticals, and the like. It has a molecular weight of about 20 kDa and and amino acid sequence which includes one or more of the following:(a) TARNEANVNIYLHLSDDEDSNYENS (N-terminus) (SEQ ID NO:1)(b) EPNAFMPGNLHHRV (SEQ ID  NO:2)(c) EHGXDTIGEL (SEQ ID NO:3)
Patent CA-2446098-A1 (CA)
Title: Tole metallique enduite antimicrobienne
Inventor: PRICE LEROY R
IPC: C09D5/14
Filed: 2002-04-30
Abstract: L'invention concerne des tôles métalliques possédant des propriétés antimicrobiennes améliorées et leur procédé de fabrication. L'invention porte, notamment, sur l'application continue sur des tôles métalliques d'une composition résineuse contenant des additifs antimicrobiens. On confère des propriétés antimicrobiennes à la surface de l'article métallique en appliquant sur la surface de la tôle métallique une dispersion ou une solution liquide de particules fines constituées d'un ingrédient antimicrobien, dispersées en couche homogène et cuites ou séchées, de sorte qu'elles se fixent à la surface métallique. Les particules antimicrobiennes inorganiques sont des oxydes portant des composants métalliques et des poudres de zéolite. Les particules centrales antibactériennes inorganiques présentent au moins un premier revêtement de surface constitué d'au moins un métal ou d'un composé métallique possédant des propriétés antibactériennes. On utilise des applicateurs à rouleau pour appliquer le revêtement. L'article métallique comprend généralement des articles en feuille faits de métaux, par exemple, des tôles métalliques en acier inoxydable, des tôles d'acier classiques ainsi que des plaques ou des tôles en aluminium.
Patent CA-2449964-A1 (CA)
Title: Crosslinkable macromers
Inventor: CLAPPER DAVID L
IPC: A61L27/00
Filed: 2001-06-07
Abstract: A crosslinkable macromer system and related methods of preparing the system and using the system in the form of a crosslinked matrix between a tissue site and an implant article such as a tissue implant or on the porous surface of a prosthetic device. The macromer system includes two or more polymer-pendent polymerizable groups and one or more initiator groups (e.g., polymer-pendent initiator groups). The polymerizable groups and the initiator group(s), when polymer-pendent, can be pendent on the same or different polymeric backbones.  The macromer system provides advantages over the use of polymerizable macromers and separate, low molecular weight initiators, including advantages with respect to such properties as nontoxicity, efficiency, and solubility. A  macromer system of the invention can be used as an interface between the tissue site and implant article in a manner sufficient to permit tissue growth through the corsslinked matrix and between the tissue site and implant. In a preferred embodiment, polymers with pendent polymerizable groups, for use in the macromer system, are prepared by reacting a polysaccharide polymer with a reactive moiety in an organic, polar solvent such as formamide.
Patent CA-2450320-A1 (CA)
Inventor: WATAHIKI MASANORI
IPC: C12Q1/68
Filed: 2002-06-07
Abstract: L'invention concerne un procédé de séquençage transcriptionnel selon lequel on peut obtenir un rapport signal/bruit élevé dans l'analyse de séquences au moyen d'un capillaire et, par ailleurs, des données de séquences nucléotidiques plus longues et plus précises dans une réaction simple. L'invention concerne en particulier un procédé pour déterminer une séquence nucléotidique d'ADN, consistant à obtenir un produit de transcription d'acide nucléique au moyen d'une ARN polymérase, une matrice d'ADN comportant une séquence promotrice pour l'ARN polymérase et des substrats de l'ARN polymérase. Les substrats de l'ARN polymérase comprennent un dérivé de 3'-désoxynucléotide. L'ARN polymérase est une ARN polymérase mutante dérivée d'une ARN polymérase de type sauvage par substitution d'au moins un acide aminé ou délétion d'au moins un acide aminé. La substitution et/ou la délétion des acides aminés sont effectuées de sorte que l'ARN polymérase mutante présente une capacité améliorée à incorporer le dérivé de 3'-désoxynucléotide comme substrat par rapport à l'ARN polymérase de type sauvage correspondante.
Patent CA-2452813-A1 (CA)
Title: Unimolecular polymeric micelles with an ionizable inner core
Inventor: RANGER MAXIME
IPC: B01J13/02
Filed: 2002-06-07
Abstract: The present invention describes the preparation of unimolecular polymeric micelles (UPM) that bear a hydrophilic shell and a potentially ionizable and relatively hydrophobic core at a determined pH value. The core becomes electrostatically charged as the pH is changed. Such micelles can be made from either biodegradable or non-biodegradable polymers. Loaded drugs can be physically retained in the micelles when the pH of the surrounding medium favors interactions with the core. Upon a change in pH, modification in the ionization state of the core will decrease the interactions between the drug and the inner core and facilitate the release of the micellar contents.
Patent CA-2456383-A1 (CA)
Inventor: AISENBREY THOMAS
IPC: H01Q5/10
Filed: 2004-01-28
Abstract: A multi-segmented planar antenna with a built in ground plane and method of forming the antenna are described. The antenna elements are formed on a layer of first dielectric having conducting material on both the first and second sides of the layer of first dielectric, such as a printed circuit board. Antenna elements are formed on both sides of the layer of first dielectric using selective etching of the conducting material. Two antenna elements are generally rectangular separated by a narrow gap and electrically connected by two shorting strips across the gap.  Two antenna elements are long and narrow wherein the length of each is an integral multiple of a quarter wavelength of the operating frequencies of the antenna.  A layer of second dielectric is placed between the layer of first dielectric having the antenna elements a nd a ground plane. The antenna can be fully encapsulated in a plastic encapsulation material.
Patent CA-2456759-A1 (CA)
Title: Identification numerique de caracteristiques de jeu uniques
Inventor: ROWE RICHARD E
IPC: G07F17/32
Filed: 2002-08-05
Abstract: L'invention concerne des procédés et un appareil destinés à générer une signature d'application de jeu (402) qui représente uniquement une application de jeu possédant plusieurs objets y étant associés. Un sous-ensemble de ces objets d'application de jeu est extrait (404). Une signature d'objet est générée (406) pour chaque objet d'application de jeu extrait. Les signatures d'objet sont combinées (408) afin de générer la signature d'application de jeu.
Patent CA-2457720-A1 (CA)
Title: Medicine containing pyrimidine derivative
Inventor: ODA TOMIICHIRO
IPC: C07D487/14
Filed: 2002-07-11
Abstract: A drug for central diseases which contains a compound represented by general formula (I), or a pharmacologically acceptable salt thereof, as active component   [R1 represents a hydrogen atom or C1-C6 alkyl group, R2 represents a C1-C6 alkyl group or the like, A represents a carbon atom or the like, D represents a C1-C6 alkylene group or the like, E represents a carbon atom or the like and Arom represents an aryl group or the like].
Patent CA-2459226-A1 (CA)
Title: Procede et dispositif destines au fonctionnement economique d'un tube fluorescent
Inventor: SCHNEIDER JURGEN
IPC: F21V19/00
Filed: 2002-09-03
Abstract: L'invention concerne un procédé et un dispositif destinés au fonctionnement économique d'un tube fluorescent, notamment d'un tube fluorescent T5. Dans un premier mode de fonctionnement, un premier filament boudiné situé sur une extrémité du tube fluorescent reçoit un premier courant de chauffage, et un deuxième filament boudiné situé sur une extrémité opposée du tube fluorescent reçoit un deuxième courant de chauffage. Le deuxième filament boudiné est relié à un circuit d'économie d'énergie. Dans un deuxième mode de fonctionnement, l'alimentation de courant de chauffage aux deux filaments boudinés est interrompue. Le dispositif selon l'invention comporte des éléments de contrôle compris dans un circuit électronique, destinés à contrôler un paramètre de fonctionnement du deuxième filament boudiné dans le premier et le deuxième mode de fonctionnement. Ledit circuit électronique permet de commander un intervalle d'alimentation du deuxième courant de chauffage au deuxième filament boudiné dépendant d'un intervalle d'alimentation du premier courant de chauffage au premier filament boudiné, en fonction du paramètre de fonctionnement contrôlé.
Patent CA-2461127-A1 (CA)
Title: Papier ignifuge et isolant
Inventor: STANG LISA B
IPC: D21H21/34
Filed: 2002-09-20
Abstract: L'invention concerne un papier ignifuge et thermorésistant possédant la capacité d'empêcher une combustion totale, comme il est de règle dans l'aéronautique. On prépare ce papier à partir de fibres de silice et d'oxyde d'aluminium modifié, apportées en complément à d'autres constituants, afin de lui conférer une résistance à la traction et une souplesse exceptionnelles par rapport aux papiers inorganiques classiques.
Patent CA-2462237-A1 (CA)
Inventor: KANE ANNE MARGARET LAMONT
IPC: C07C335/32
Filed: 2002-10-03
Abstract: A process for preparing a compound of formula (II) of use as an intermediate in the preparation of fulvestrant:   (see formula II) where n is an integer of from 3 to 14; R1 is haloC1-10alkyl and R2 is a halo group;  the process comprising halogenation of a compound of formula (III) (see formula III) .   Novel compounds are also described and claimed. Compounds of formula (II) are useful as intermediates in an improved process for preparing fulvestrant which involves fewer steps than prior art processes.
Patent CA-2463502-A1 (CA)
Inventor: WELCH DAVID F
IPC: H04B10/29
Filed: 2002-10-08
Abstract: L'invention concerne les réseaux optiques numériques (DON), une nouvelle approche des modules d'émission et de réception optiques plus compacts et de faible coût utilisés dans les réseaux de transport optiques (OTNs). Ces réseaux optiques numériques se caractérisent par l'incorporation dans ces modules de microcircuits intégrés photoniques d'émission (TxPIC) et de microcircuits intégrés photoniques de réception (TxPIC) au lieu de sources modulées discrètes et de sources de détection comprenant des multiplexeurs ou des démultiplexeurs discrets.
Patent CA-2464244-A1 (CA)
Inventor: HEYDER ROGER V
IPC: E05B65/08
Filed: 2004-04-19
Abstract: A compact, portable device for effectively locking a crank window in a user selected position. The body of the device can be selectively secured to or released from a window crank. When secured to the window crank, the device limits rotation of the crank by mechanical interference.
Patent CA-2464756-A1 (CA)
Title: Procede pour former des cristaux de profenes
Inventor: MULLER BERND W
IPC: C07C57/30
Filed: 2002-10-25
Abstract: La présente invention concerne un procédé pour former des cristaux de profènes, caractérisé en ce que la solidification est provoquée par un procédé de précipitation par déplacement, de cristallisation par refroidissement, de cristallisation par évaporation, ou par une combinaison de ces procédés, en présence d'un ou de plusieurs additifs. L'invention concerne par ailleurs l'utilisation des profènes ainsi produits dans des formulations pharmaceutiques.
Patent CA-2464912-A1 (CA)
Inventor: SPITZ GERHARD
IPC: B21C37/08
Filed: 2004-04-08
Abstract: A method and a roll-forming system for producing a metal profile are provided, wherein the wall thickness of the metal profile varies along its longitudinal axis. For this purpose, a sheet-metal strip with a thickness that varies along its length is used. Before welding together the profile or tube, which is manufactured through shaping into a closed profile or tube, this piece is sized to a desired outer diameter and in this way any existing ripples in the strip edges are made level, so that a simple, conventional straight welding of the profile or tube is possible.
Patent CA-2468125-A1 (CA)
Inventor: PILLUTLA RENUKA C
IPC: G01N33/68
Filed: 2002-10-24
Abstract: The present invention relates to a modified phage display method for detecting and identifying target and target binders. The modified methods involve transforming host cells with two separate phages, one comprising a target or target library and the other comprising a target-binder library, and selecting to eliminate the non-paired targets and binders. Also related are complexes comprising target and target binders, as well as antibodies that bind to these complexes. Additionally, the present invention also relates to nucleic acids encoding target and target binders peptides. The invention also relates to the use of the sequence information inherent in the targets and target binders for target validation using in silico approaches. In addition, the invention also relates to diagnostics and therapeutics employing the disclosed target and target binder pepetides or polynucleotides and their use in small molecule drug discovery. In particular, the present invention relates to diagnostic and therapeutic applications directed to cancers and similar disorders and the isolation of small molecule drugs by using the target and target binders to generate site directed assays for high throughput drug screening.
Patent CA-2471713-A1 (CA)
Title: Benzothiazole- and benzoxazole-4,7-dione derivatives and their use as cdc25 phosphatase inhibitors
Inventor: PREVOST GREGOIRE
IPC: A61P33/00
Filed: 2002-12-24
Abstract: The invention concerns the use as cdc25 phosphatase inhibitors, in particular cdc25-C phosphatase, and CD45 phosphatase, of compounds of general formula (I), wherein: W represents O or S. In accordance with the invention, the compounds of general formula (I) can in particular be used for preparing a medicine for cancer treatment.
Patent CA-2472317-A1 (CA)
Inventor: NAUDET JACKY
IPC: F01D5/14
Filed: 2004-06-23
Abstract: L'aube de compresseur de moteur à turbine à gaz de l'invention comprend un pied à attache marteau pour être inséré dans une gorge circonférentielle du rotor du compresseur, une plate-forme (12) solidaire du pied et supportant une pale (13), la plate-forme comprenant deux bords perpendiculaires à l'axe du rotor (20, 21) et deux flancs (22, 23) incurvés, la courbe des flancs étant construite à partir d'au moins une courbe définie pa r une équation, le centre de courbure du point de la courbe dont le rayon de courbure est le plus faible se situant à l'intérieur d'une bande (B) centrale à la plate-forme (12) et représentant 60% de la largeur (D) de la plate-forme (12) mesurée entre ses bords rectilignes parallèles (20, 21), l'équation définissant la courbe étant, au sens des fonctions mathématiques, continue et à dérivée première continue. Figure pour l'abrégé : figure 5.