baber/WOPTO huggingface dataset:
Patent CA-2575804-A1 (CA)
Title: Pteridinones used as plk (polo like kinase) inhibitors
Inventor: STEEGMAIER MARTIN
IPC: C07D475/00
Filed: 2005-08-19
Abstract: The invention relates to compounds of general formula (1), wherein L, Q1, Q2, X, Y, Ra, Rb, Rc, R1, R2, R3, and R4 are defined as indicated in claim 1. Said compounds are suitable for the treatment of diseases characterized by excessive or anomalous cell proliferation. Also disclosed is the use of said compounds for producing a medicament having said properties.
Patent CA-2582129-A1 (CA)
Inventor: TANG YAN
IPC: F04C18/00
Filed: 2004-10-06
Abstract: A compressor includes a male rotor (26) having a screw-type boy portion (30) extending from a first end (31) to a second end (32) and held within a housing assembly for rotation about a first rotor axis (500). A female rotor (27, 28) has a screw-type female body portion (33, 34) meshed with the male body portion and extending from a first end (35, 36) to a second end (37, 38) and held within the housing assembly for rotation about a second rotor axis (501, 502). An end seal (120) has a first surface (126) engaging the female body portion first end and being asymmetric around the second axis.
Patent CA-2582771-A1 (CA)
Inventor: KAYAN HELMUT L
IPC: A61B17/03
Filed: 1999-06-29
Abstract: A fastening apparatus is disclosed for use in endoscopic surgery. The apparatus comprises a handle portion; a triggering mechanism; and a fastener applicator having a plurality of biased springs.
Patent CA-2583777-A1 (CA)
Title: Polycondensation product based on aromatic or heteroaromatic compounds, its production process and use
Inventor: GRASSL HARALD
IPC: C08G8/28
Filed: 2005-10-14
Abstract: Disclosed is a polycondensation product comprising A) an aromatic or heteroaromatic compound containing 5 to 10 C atoms or heteroatoms, said compound being provided with an average of 1 to 300 oxyethylene groups and/or oxypropylene groups per molecule which are linked to the aromatic or heteroaromatic compound via an O atom or N atom, and optionally B) an aromatic compound selected among the group comprising phenols, phenol ether, naphthols, naphthol ether, anilines, furfuryl alcohols, and/or an aminoplast former selected among the group comprising melamine (derivatives), urea (derivatives), and carboxylic acid amides, and C) an aldehyde selected among the group comprising formaldehyde, glyoxylic acid, and benzaldehyde or mixtures thereof, the benzaldehyde optionally containing acid groups in the form of COOMa, SO3Ma, and PO3Ma, wherein M = H, akali metal or alkaline earth metal, ammonium, or organic amine radicals and a = 1/2, 1, or 2. Surprisingly, the inventive polycondensation product causes very good liquefaction of hydraulic binding agents, e.g. cement, resulting in substantially improved liquefaction of the construction material at a lower dose while pourability can be maintained over a longer period of time as opposed to naphthalene sulfonates or melamine sulfonates.
Patent CA-2584727-A1 (CA)
Inventor: MOHSIUL ALAM
IPC: F01D25/16
Filed: 2005-10-19
Abstract: The present invention provides a centering feature (26) to the bearing assembly (48) of a turbomachine (10) to provide optimum operating characteristics of the squeeze film damper (24). Unlike conventional bearing centering methods and apparatus, a compact compliant centering support (26) for the squeeze film damper (24) interfaces between a bearing outer race (20), and an outer support structure (14). The compact compliant centering support damper may be comprised of a ring with bumpers (32, 34) spaced around the circumference at the inside and outside diameters to form spring elements between the bumpers. The centering support (26) may lift the rotor inside the squeeze film cavity and may eliminate rotor weight effect on the damper performance. The centering support (26) may be offset in the vertical direction to center the rotor under 1 g deflection to eliminate rub at the 6 o'clock location of a compressor or turbine shroud. Tangential grooves (36) may be provided on the centering support outer bumpers (32) to allow oil to squeeze out when the centering support is deflected to provide additional viscous damping. The outer bumper height (38) may be con~trolled to limit maneuver deflection of the rotor.
Patent CA-2585530-A1 (CA)
Inventor: SAVALL CALVO JOAN
IPC: A61B17/34
Filed: 2005-10-07
Abstract: Support or micromanipulator (100) for a surgical tool (20) comprising a complaint mechanism (1) providing direct support to the surgical tool (200), a positioning mechanism giving support to said complaint mechanism, and an attachment mechanism giving support to said positioning mechanism. The complaint mechanism (1) is made of a complaint material and allows three or four degrees of freedom to the movement of the tool (200). The positioning mechanism is located between the attachment mechanism and the complaint mechanism (1) and allows positioning of the same with six degrees of freedom.  The attachment mechanism fastens the assembly to a surface of the surgical intervention region. The micromanipulator (100) is especially useful for practicing surgical interventions in the cochlea (performing cochlear implants, obtaining samples, etc), or other interventions for which high precision with the tool (200) is required.
Patent CA-2587757-A1 (CA)
Title: A system and method for managing electronic records
Inventor: HUNTER GREGORY S
IPC: G06F17/30
Filed: 2007-05-04
Abstract: A method for managing electronic records is provided. Each electronic record includes a data file, a plurality of data files, a portion of a data file, or portions of a plurality of data files.  The electronic records include a plurality of record types and data file types. The method includes forming a data file set comprising one or more logically related data files; identifying attributes of each record type in a record type template; identifying specifications of each data file type in a data file type template; and extracting digital components from the data file set.  The extracted digital components relate to the attributes in each record type template and the specifications in each data file type template and compose an individual record. The templates reference are mapped and related across a hierarchical and networked taxonomy.  Analyzing semantic coherence within a given template taxonomy allows records to be defined, delineated and managed. An electronic record archive includes record type and data file type templates and a digital component extractor.
Patent CA-2587974-A1 (CA)
Inventor: DUNHAM STEVE
IPC: A63H17/26
Filed: 2007-05-04
Abstract: A toy vehicle. The toy vehicle includes a body with at least one rollable wheel operatively connected to the body, and a pneumatic system operatively connected to the body and configured to store a pressurized gas and release stored gas upon a triggering event. A lifter is operatively connected to the at least one wheel and is configured to use energy from the pressurized gas to cause the toy to jump responsive to the triggering event, at least in part, by extending the at least one wheel.
Patent CA-2589471-A1 (CA)
Title: Antibodies and peptide antigens for producing antibodies having a selective binding specificity to bioactive intact parathyroid hormone (pth) 1-84
Inventor: LAVIGNE JEFFREY R
IPC: C12P21/04
Filed: 2005-11-29
Abstract: Peptide antigens corresponding to amino acid residues 2-12, 1-12, 2-15 and 1-15 of parathyroid hormone (PTH), antibodies having an affinity to such peptide antigens and methods of producing the same. Such antigens, antibodies and methods producing the same according to the present invention are useful in determining bioactive intact PTH levels in serum, plasma, and/or cell culture media. Such antibodies further possess a high degree of species cross-reactivity, but substantially mitigated cross-reactivity to non-whole PTH  peptide fragments and little to no recognition of the first amino acid residue of PTH.
Patent CA-2589644-A1 (CA)
Title: Mda-7 protein variants having antiproliferative activity
Inventor: GUPTA PANKAJ
IPC: G01N1/10
Filed: 2005-12-02
Abstract: The invention relates to the mda-7 gene, its encoded protein and fragments of the proteins. Several of these fragments of the MDA-7 protein exhibit antiproliferative activity and/or inhibited the activity of intact MDA-7.  Accordingly, the invention provides, among other things, for methods and compositions that may be used in the treatment of disorders of cell proliferation, including cancer.
Patent CA-2593448-A1 (CA)
Title: Aligned and axially loaded pig injector valve and method of attaching
Inventor: WIECEK BOGUSLAW
IPC: F16L15/00
Filed: 2005-02-03
Abstract: A method of attaching a tubular member, having an attachment flange defining a plurality of bolt holes, to a valve fitting comprising a valve body having a loading surface and a valve flange. The valve flange includes a flange, defining a plurality of bolt holes, for engaging the attachment flange and a plurality of axial loading members movable between a first retracted position and a second extended position protruding to bear on the loading surface. The method includes threading a threaded end of the valve flange onto a threaded end of the valve body, rotating the valve flange until the bolt holes of the valve flange are geometrically aligned with the bolt holes of the tubular member and moving at least one of the axial loading members into its second extended position to bear on the loading surface to impart an axial tensile force between the valve body and valve flange.
Patent CA-2594285-A1 (CA)
Inventor: FARRELLY BRIAN ANTHONY
IPC: G01V3/12
Filed: 2006-01-09
Abstract: A method for determining electrical properties of a submarine petroleum fluid-bearing formation (1) under overburden geological layers (2) of thickness (s) under a seafloor (3) of a sea (4), said method comprising the following steps:  * arranging one or more transmitter antennas (9) in said sea (4), and arranging one or more electromagnetic receivers (8) in said sea (4), * said sea having a shallow sea depth (d) of 50 - 350 meters; * using said transmitter antenna (9) transmitting electromagnetic signals (10) of one or more pulses (11) having frequency of very low frequency between 0.01 Hz and 0.10 Hz; * using said receiver antennas (8) having an offset from said transmitter (9), for receiving propagated electromagnetic signals (12) due to said emitted electromagnetic signals (10); * analysing one or more components of said received signals (12) from receivers (8) having offsets between about 1 km and 12 km, whether said signals (12) differ significantly from a corresponding signal that would occur from a water-bearing formation (1 ), indicating a petroleum fluid-bearing formation (1).
Patent CA-2595724-A1 (CA)
Title: Articulated foldable sandals
Inventor: MARTINEZ BENJAMIN
IPC: A43B3/12
Filed: 2005-10-04
Abstract: An articulated foldable sandal (10) may include a sole (12) having a forefoot portion (16) that is adapted to be disposed under a front portion of a wearer's foot and a rear-foot portion (18) that is adapted to be disposed under a rear portion of the wearer's foot. The sole (12) may also have an articulating member (24) that may be operatively coupled to both the forefoot portion (16) and the rear-foot portion (18). The articulating member (24) may include at least two distinct axes of rotation (40,42) and may be adapted to enable the sandal (10) to be selectively moved between an open configuration suitable for wearing and a folded configuration. The sandal (10) may also include a retaining member (14) fastened to the sole (12) and adapted to hold the sandal (10) on a wearer's foot.
Patent CA-2596575-A1 (CA)
Title: Ultrasonic welding device
Inventor: WILD HANS-PETER
IPC: B23K37/04
Filed: 2007-08-09
Abstract: Described is an ultrasonic welding device (1), comprising a sonotrode (8) and an anvil (7) for welding foil layers together by introducing a force. The foil layers are thereby located in a receiving gap (6) provided between an effective plane (11) of the sonotrode (8) and an effective plane (12) of the anvil (7). In order to embocy the ultrasonic welding device to improve the quality of the welding seams a component (~) of the force introduction, which is directed opposite to the direction of the gravity (G), is generated.
Patent CA-2598518-A1 (CA)
Title: 5-phenyl-pentanoic acid derivatives as matrix metalloproteinase inhibitors for the treatment of asthma and other diseases
Inventor: SATTIGERI VISWAJANANI JITENDRA
IPC: C07D237/32
Filed: 2006-02-21
Abstract: The present invention relates to C ompounds having the structure of Formula I:  wherein n is an integer from 1 to 5; R1 is optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heterocyclyl, heteroaryl, aralkyl, alkoxy, aryloxy, alkenyloxy or alkynyloxy; R2 is alkenyl, allcynyl, aryl, heterocyclyl, heteroaryl, cycloalkyl, NR4R5, -NHC(=Y)R4, - NHC(=Y)NR5R.chi., -NHC(=O)OR4, -NHSO2R4, C(=Y)NR4R5, C(=O)OR6 [wherein Y is oxygen or sulphur], OR5, -O(C=O)NR4R5, O-acyl, S(O)mR4, -SO2N(R4)2, cyano, amidino or guanidino [wherein R4 is alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heterocyclyl, heteroaryl, aralkyl, heteroarylalkyl, heterocyclylalkyl or cycloalkylalkyl and m is an integer 0-2; R5 is hydrogen or R4; Rx is R4 or -SO2N(R4)2 and R6 is hydrogen, alkyl, cycloalkyl, aralkyl, heteroarylalkyl, heterocyclylalkyl or cycloalkylalkyl]; R3 is hydrogen, fluorine, alkyl, cycloalkylalkyl or aralkyl;  A is OH, OR4, -OC(=O)NR4R5, O-acyl, NH2, NR4R5, -NHC(=Y)R4, -NHC(=Y)NR5Rx, -NHC(=O)OR4, -NHSO2R4, and to processes for the synthesis of the same. This invention also relates to pharmacological compositions containing the compounds of the present invention, and methods of treating asthma, rheumatoid arthritis, COPD, rhinitis, osteoarthritis, psoriatic arthritis, psoriasis, pulmonary fibrosis pulmonary inflammation, acute respiratory distress syndrome, perodontitis, multiple sclerosis, gingivitis, atherosclerosis, neointimal proliferation, which leads to restenosis and ischemic heart failure, stroke, renal diseases, tumor metastasis, and other inflammatory disorders characterized by over-expression and over-activation of an matrix metalloproteinase, using the compounds.
Patent CA-2599130-A1 (CA)
Title: Method for modeling and testing a security system
Inventor: JOHNSON DENNIS J
IPC: G06F17/50
Filed: 2006-02-23
Abstract: A method of designing, modeling, and testing a security system for protecting a defined security area. The method includes modeling the security area, modeling the security system for the security area, and testing the security system using a computer to run one or more breach scenarios to determine whether there are any weaknesses in the security system. The testing may be in the form of a computer game with one or more players implementing the models and one or more breach scenarios and/or in real-time.
Patent CA-2600073-A1 (CA)
Inventor: LI QIAN-YI
IPC: A47L13/17
Filed: 2006-02-16
Abstract: The invention relates to a product for the targeted release of active substances, especially detergents and/or cosmetic active substances. The inventive product comprises at least three layers, a first layer being impermeable to the active substance and a second layer being permeable to the active substance. An interposed layer has the effect of defining two spatially separate compartments. The first compartment contains the active substance and the second compartment contains a gas-releasing component. The product is preferably suitable for single use and can be used as a cosmetic agent and/or as a cleaning agent.
Patent CA-2601472-A1 (CA)
Title: Hydrolases, nucleic acids encoding them and methods for improving paper strength
Inventor: WEINER DAVID
IPC: A23L35/00
Filed: 2006-03-08
Abstract: The invention provides hydrolases, polynucleotides encoding them, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention is directed to polypeptides, e.g., enzymes, having a hydrolase activity, e.g., an esterase, acylase, lipase, phospholipase (e.g., phospholipase A, B, C and D activity, patatin activity, lipid acyl hydrolase (LAH) activity) or protease activity, including thermostable and thermotolerant hydrolase activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The hydrolase activities of the polypeptides and peptides of the invention include esterase activity, lipase activity (hydrolysis of lipids), acidolysis reactions (to replace an esterified fatty acid with a free fatty acid), transesterification reactions (exchange of fatty acids between triglycerides), ester synthesis, ester interchange reactions, phospholipase activity and protease activity (hydrolysis of peptide bonds). In another aspect, the invention provides methods for hydrolyzing steryl esters and triglycerides (e.g., in a paper pulp), into sterols, glycerol and free fatty acids, using enzyme(s) of the invention. The invention provides enzymes and methods for decreasing the amount of lipophilic extracts ("pitch") in a pulp- comprising composition. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural and industrial contexts, including the manufacture of cosmetics and nutraceuticals.
Patent CA-2602754-A1 (CA)
Title: Measurement system for improved paper roll runnability
Inventor: HELLSTROM AKE
IPC: D21G9/00
Filed: 2006-05-12
Abstract: A system for measuring both caliper and tension of a web such as paper wound into a roll (10) . The system may include a standard caliper sensor whose ai r supply is selectively modified to allow for both the measurement of caliper and tension of the web. In another embodiment two similar or identical measurement devices are installed in tandem where one device measures tensio n without pinching the sheet and the other device measures caliper. The sensor may include two sheet guides (70, 72) for providing support for tension measurement or one or both sheet guides can be eliminated by support from machinery rolls.
Patent CA-2606301-A1 (CA)
Inventor: PETRY STEFAN
IPC: A61K31/423
Filed: 2006-04-13
Abstract: The invention relates to azole derivatives of formula (I) whose meanings are given in a description and to salts thereof which can be pharmaceutically used in the form of drags.
Patent CA-2607937-A1 (CA)
Inventor: KARIM KARIM S
IPC: G01N21/63
Filed: 2007-10-29
Abstract: A multi-channel bio-separation detection method and apparatus in which an array of detectors are coupled to a plurality of radiation sources. Each radiation source directs radiation at one detection zone of a single separation channel, and each detector is applied to detect light emissions from the detection zone of that channel. The light sources direct radiation at the detection zones in a predetermined sequence, with the detector output synchronized to the light sources by a controller. Bio-separation is conducted simultaneously in all the channels in parallel, with detection time-staggered and/or time multiplexed with respect to the light sources. In one embodiment, low power light emitting laser diodes may be used as light sources.
Patent CA-2608554-A1 (CA)
Title: Sanitary product
Inventor: HOOI ALEX YU SING
IPC: A61F13/472
Filed: 2006-05-17
Abstract: This invention relates to a sanitary product (1) for use by women for the absorption of menstrual fluid and such like. The product (1) comprises a plug (2) and a pad (3) joined by a sheath (4). The plug (2) is substantially cylindrical so that is fits comfortably in a vaginal cavity. The pad (3) remains outside the vaginal cavity, but has an absorbent layer on an inward side (10) proximal to the plug (2) and a liquid impermeable layer on an outward side (11). In use, a wearer can insert a finger into the sheath (4) from the outward side (11) of the pad (3) assist with insertion of the plug (2) into the vaginal cavity. A string (12) is provided that extends inside the sheath (4) from the outward end of the plug (2) to aid removal of the product (1). A line of weakness (7) extends along the major axis of the pad (3), about which the pad (3) is disposed to fold in use. This encourages the pad (3) to fold around the plug (2) to accommodate the plug (2) during removal of the product (1) , thus improving hygiene.
Patent CA-2609234-A1 (CA)
Title: Anti-il2 antibodies
Inventor: PFLANZ STEFAN
IPC: C12N15/13
Filed: 2006-05-31
Abstract: The invention relates to a humanized monoclonal antibody or fragment thereof which specifically binds to human interleukin-2 (IL2), wherein said humanized monoclonal antibody neutralizes the activity of human IL2 by binding to said human IL2 prior to, during, and/or subsequent to the binding of said human IL2 to the human IL2-receptor, and wherein the light chain variable region of said humanized monoclonal antibody comprises in its second framework region the contiguous amino acid sequence KAPKA at amino acid positions 42-46.
Patent CA-2612209-A1 (CA)
Title: Network id activated transmitter
Inventor: FITZGIBBON JAMES J
IPC: G08C17/02
Filed: 2007-11-23
Abstract: A security code transmitter is provided to transmit a control signal to a barrier movement operator to controlling movement of a movable barrier. The barrier movement operator is proximate to a wireless communication network having a network ID. A receiver of the security code transmitter receives a transmitted network signal comprising the network ID from the wireless communication network. A memory of the security code transmitter stores a predetermined ID. A processor of the security code transmitter determines whether the wireless network ID of the transmitted network signal matches the predetermined wireless network ID. When a match is determined, the security code transmitter is controlled to transmit the control signal to the barrier movement operator.
Patent CA-2615596-A1 (CA)
Title: Ethanolamine salt of n- (3-methoxy-5-methylpyrazin-2yl) -2- (4- [1 , 3 , 4-oxadiazole-2-yl] phenyl) pyridine-3- sulphonamide
Inventor: GOOD CATHERINE
IPC: A61K31/497
Filed: 2006-07-17
Abstract: N-(3-Methoxy-5-methylpyrazin-2-yl)-2-(4-[1,3,4-oxadiazol-2-yl]phenyl)pyridine-3-sulphonamide ethanolamine salt and its uses are described.
Patent CA-2620363-A1 (CA)
Title: Naphthalene-disulfonamides useful for the treatment of inflammation
Inventor: PELCMAN BENJAMIN
IPC: C07D213/61
Filed: 2006-10-13
Abstract: There is provided compounds of formula (I), wherein R1, R2, X2, X4 and X5to X8 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation.
Patent CA-2620523-A1 (CA)
Inventor: LABRECQUE ROBERT
IPC: A01K29/00
Filed: 2008-01-31
Abstract: The number of piglets dying at birth is reduced by providing a temperature sensor in a farrowing crate at the piglet area thereof on a movable cover so that, when the sow is expected to give birth, the sensor is located in the crate at a location to detect the presence of one or more piglets after birth.  On detection by a control unit using the sensor signal of the one or more piglets, the sensor communicates a signal to a pager carried by an operator indicating to the operator that birth of piglets is in progress and activates a heating lamp for the piglets in the pen to attract them away from the area of the sow to reduce crushing. The control unit and the sensor also control the heat output. The cover can slide along the piglet area and can lift to expose the piglet area.
Patent CA-2621866-A1 (CA)
Title: Stable solid formulation of sertindole
Inventor: CHRISTENSEN ANNE RAVNHOLDT
IPC: A61K31/454
Filed: 2006-09-06
Abstract: The present invention relates to a pharmaceutical composition comprising sertindole and a protective agent absorbing radiation with a wavelength below 400 nm. The present invention also relates to the use of sertindole for the preparation of a pharmaceutical composition comprising sertindole and a coating layer comprising said protective agent, such as ironoxide, for the treatment of schizophrenia.