baber/WOPTO huggingface dataset:
Patent CA-2214410-A1 (CA)
Title: Peptide and a method of obtaining it
Inventor: DEIGIN VLADISLAV ISAKOVICH
IPC: C07K5/065
Filed: 1996-02-28
Abstract: The invention relates to medicine, specifically, to methods of obtaining biologically active substances with immuno-regulating properties, and can be used in medicine and veterinary science and in experimental biochemistry. The fundamental problem addressed by the invention is that of producing a novel synthetic biologically active peptide with immuno-regulating properties and of the formula: X-Glu-Trp-Y, in which X is H or Gly, Ala, Leu, Ile, Val, NVal, Pro, Tyr, Phe, Trp, D-Ala, D-Leu, D-Ile, D-Val, D-NVal, D-Pro, D-Tyr, D-Phe, D-Trp, .gamma.-aminobutyric acid, -aminocaproic acid; Y is Gly, Ala, Leu, Ile, Val, NVal, Pro, Tyr, Phe, Trp, D-Ala, D-Leu, D-Ile, D-Val, D-NVal, D-Pro, D-Tyr, D-Phe, D-Trp, .gamma.-aminobutyric acid, - aminocaproic acid, -OH, mono-or di-substituted amide (C1-C3). Peptide synthesis takes place in a solution by successive growth of a chain from the C termination of the molecules, using a strategy of maximum blocking of functional groups, starting from amino acid alkyl ether, using the method of activating the ethers and the method of mixed anhydrides using tributyloxicarbonyl amino acid.
Patent CA-2219643-A1 (CA)
Title: Bioreactor
Inventor: KERSTEN JEAN
IPC: C12M3/06
Filed: 1996-04-22
Abstract: The invention concerns a bioreactor for the cell-treatment of fluids. The bioreactor comprises a component defining a chamber in which are disposed fluid-treatment cells, a liquid-permeable membrane which separates the chamber from a first channel in which the fluid to be treated flows, and a gaspermeable membrane separating the chamber from a second channel in which an oxygenous gas flows. The chamber comprises two cell layers separated by a permeable layer.
Patent CA-2219821-A1 (CA)
Inventor: HAMMILL LINDA D
IPC: C07K14/78
Filed: 1996-06-06
Abstract: La présente invention concerne des gènes hybrides comprenant une séquence nucléotidique codant une séquence-signal de préprocollagène fonctionnellement liée à une séquence nucléotidique codant une protéine hétérologue. Ces gènes hybrides conviennent à la sécrétion de protéines hétérologues à partir de cellules hôtes. Dans une réalisation préférée, la séquence-signal de la protéine du préprocollagène .alpha.1(I) d'origine humaine se lie à la protéine hétérologue considérée pour permettre la sécrétion de la protéine issue de cellules de Hansenula polymorpha.
Patent CA-2220563-A1 (CA)
Title: Protein production in transgenic alfalfa plants
Inventor: KHOUDI HABIB
IPC: C12N15/13
Filed: 1997-11-10
Abstract: This invention is directed to characterizing a host system suitable for the production of functional transgenic proteins, such as anti-human IgG, for use in applications requiring Government regulatory approval. It is well known that regulatory agencies required stable, consistent master cell banks and master cell lines for the production of transgenic proteins in order to ensure sufficient material for appropriate characterization, clinical trials, and potential sales. Current plant production systems require the establishment of seed banks for this purpose. However, there are many draw backs related to such a system for the production of a continuous reliable transgenic protein source. An aspect of this invention is directed to characterizing a plant production system suitable for transgenic proteins that meet the stringent regulatory requirements. Another aspect of this invention exemplifies the production and characterization of an anti-human IgG for use as a blood grouping reagents, through the expression of corresponding genes in transgenic alfalfa plants. The cDNAs of the heavy and light chains of a human IgG-specific IgG2a(kappa) murine mAb (C5-1) were transferred into alfalfa through Agrobacterium infection. Transgenic plants expressing the light- and heavy-chain encoding mRNAs were obtained and plants from the F1 progeny (obtained by sexual crossing) were found to express fully assembled C 5-1. Furthermore, the transgenic protein was stable in vivo, as well as during extraction and purification procedures. Purification yielded a unique H2L2 form with a reactivity indistinguishable from hybridoma-derived C 5-1 in standardized serological tests. Results indicate that plant-derived transgenic proteins, such as mAbs can be used as diagnostic reagents as effectively as hybridoma- derived mAbs, and demonstrates the usefulness of the transformed alfalfa system to produce large amounts of proteins, including multimeric proteins such as mAbs.
Patent CA-2223838-A1 (CA)
Title: Volumetric infusion pump
Inventor: TURNER JOHN M
IPC: F04B53/16
Filed: 1997-03-21
Abstract: A medical infusion pump is disclosed which provides for greatly improved accuracy in the delivery of medica-ments to a patient. Among the various features included in the instant invention is a pumping body which serves to deform and reform a tube so as to maintain the initial cross section thereof and thereby preserve the output accuracy of the pump. Also disclosed with regard to the pumping body is a wholly mechanical synchronization of the pump-ing body and valves associated therewith and coactive with the aforementioned synchronization a mechanical lineariza-tion of output of the pumping body per each pumping cy-cle. Additionally, several features which serve to enhance the utility of the instant invention are also included therein among which is an associated assembly operative to auto-matically load or disload a tube or IV set into or out of the pumping body. Associated with the assembly operative to automatically load or disload a tube and disclosed herein is an assembly operative to selectively open or close a slide clamp associated with the tube in such a way as to ensure that the tube is occluded such that in combination with the valves associated with the pumping body, a condition of free-flow of medicament is never realized. Additionally disclosed are sensor housings adapted to measure various quantities associated with fluid flowing through the tube wherein the housings are with associated components adapted to achieve a substantially normal orientation with respect to the sidewall of the tube and in the achieving of such normal orientation, expressing an essentially zero elastic stress gradient across the tube.
Patent CA-2226051-A1 (CA)
Title: Row unit crop guide for harvesting multiple rows
Inventor: KERBER DATHAN R
IPC: A01D45/02
Filed: 1997-12-30
Abstract: A row crop header for a harvesting machine includes a frame, a row unit supported by the frame, a first surface supported by the frame forward the row unit on a first side of the row unit, a second surface supported by the frame forward the row unit on a second side of the row unit, a third surface supported by the frame between the first and second surfaces,  and a fourth surface  supported by the frame between the first and second surfaces.  The first and second surfaces face one another and converge toward the row unit.   The third surface faces the first surface to cooperate with the first surface so as to support and channel plants toward the row unit.   The fourth surface faces the second surface to cooperate with the second surface so as to support and channel plants toward the row unit.
Patent CA-2226334-A1 (CA)
Title: Unite de formation de faisceau de canaux multiplexes
Inventor: RENAUD DANIEL
IPC: H01Q3/26
Filed: 1998-02-02
Abstract: L'invention fournit une unité pour combiner N signaux de canal (R0, R1, R2), N étant un nombre entier, lesdits N signaux de canal (R0, R1, R2) étant produits par N sources (30, 31, 32) respectives séparées. L'unité est caractérisée en ce qu'elle comprend des moyens de réseau collecteur (50) desdits N signaux de canal combinés, lesdits moyens de réseau collecteur (50) recevant ladite pluralité de signaux de canal (R0, R1, R2) selon des directions respectives définies par des lobes de réseau associés auxdits moyens de réseau collecteur (50).
Patent CA-2229403-A1 (CA)
Inventor: SUHONEN JOUKO
IPC: A61C5/88
Filed: 1998-02-11
Abstract: The dental medicine device comprises an elongated inflatable balloon 10 for placement around a matrix band 23 in part surrounding relationship with a decayed tooth 24. Upon inflation, the balloon 10 evenly applies the matrix band 23 against the tooth.
Patent CA-2231372-A1 (CA)
Inventor: WELLS JEREMY MARK
IPC: C12N15/09
Filed: 1996-09-06
Abstract: Methods for obtaning surface expression of a desired protein or polypeptide in Gram-positive host organisms are provided. In addition, vectors useful in such methods as well as Gram-positive host organisms tranformed with such vectors are disclosed.
Patent CA-2232486-A1 (CA)
Inventor: FAORO FRANCISCO
IPC: B41J2/17
Filed: 1998-03-17
Abstract: The ink reservoir comprises a bottle (1) into which is installed a foil bag (2). The bag (2) is designed at both axial ends as standing bag. In one, in the bag (2) welded-in, thermoplastic stub (23) is installed an elastomer stopper (27) for insertion of a first hollow needle of the plotter. The stub (23) is snapped into a lid (4) of bottle (1) below a passage opening (44). The lid (4) is snapped onto the bottle (1). Below the lid (4), an absorbent body (3) is installed in the bottle (1) which surrounds the bag. By means of another opening (45) in lid (4) a second hollow needle of the plotter is inserted into the absorbent body (3). The absorbent body serves for acceptance of waste ink. With the described design, one attains simple handling during shipping and installation in the plotter.
Patent CA-2233416-A1 (CA)
Title: Pipe coupling
Inventor: WEINHOLD KARL
IPC: F16L19/02
Filed: 1998-03-27
Abstract: The invention relates to a pipe coupling comprising a socket component and an insert component which is partially insertable to securely fit into the socket component. A ring groove between the socket component and the insert component is sealed by a ring seal. The socket component is releasably connected to the insert component by means of a union nut which contacts a shoulder of the insert component rearwardly for joined movement into the closed position. The union nut is screwed onto the socket component along a cylindrical and/or conical exterior thread. The ring gap between the union nut and the insert component is sealed. The ring gap between the union nut and the socket component is also sealed. The thread connection between the socket component and the union nut is positioned between the two sealing positions.
Patent CA-2234378-A1 (CA)
Title: Container
Inventor: GRAF OTTO PETER
IPC: B65D45/16
Filed: 1998-04-06
Abstract: The container consists of two shells which face each other and are mounted to each other at their port edges by means of wedge type fastener structures. To this end each shell includes a plurality of semi-wedges arranged distributed along the circumference. Two opposite semi-wedges of the two shells complete themselves to a complete wedge. A separately provided wedge clams is slid over every complete wedge, which wedge clamp grips around the complete wedge and presses the two semi-wedges of each complete wedge and accordingly the two port edges together.
Patent CA-2234807-A1 (CA)
Title: Metalation and functionalization of polymers and copolymers
Inventor: FRECHET JEAN M J
IPC: C08F8/00
Filed: 1996-06-06
Abstract: There is provided a method of introducing functionality into a copolymer of an isoolefin and an alkylstyrene at the alkylbenzyl carbon atom comprising the steps of: forming a solution of said copolymer in a hydrocarbon solvent; adding to said polymer solution an alkali metal Na, K, Rb, Cs alkoxide and an alkyl lithium compound to form a superbase with the polymer solution; and adding an electrophile to the metalated polymer solution; also provided are the metalated copolymers and the functionalized derivatives therefrom.
Patent CA-2236577-A1 (CA)
Title: Light-sensitive resist which can be developed in an aqueous-alkali manner and operates negatively
Inventor: SAUER ERIKA
IPC: H01L21/312
Filed: 1997-06-05
Abstract: The invention relates to a light sensitive, aqueous alkali developing, negatively acting resist, comprising a phenolic resin as a binder, and a diazostilbene disulfonic acid ester light sensitive component, a solvent or mixture of solvents, and film forming and/or film stabilizing additives, and to a process for preparing the light sensitive component.
Patent CA-2237937-A1 (CA)
Title: Novel purinergic receptor
Inventor: JANTZEN HANS-MICHAEL
IPC: G01N33/566
Filed: 1996-11-08
Abstract: Novel purinergic receptors are provided, having research, diagnostic and therapeutic applications. Also provided are nucleic acids encoding these receptors, as well as expression systems for their production.
Patent CA-2238129-A1 (CA)
Title: Therapeutic exercise program
Inventor: DARDIK IRVING I
IPC: G16H20/30
Filed: 1998-05-15
Abstract: A therapeutic exercise program for treating a patient whose abnormal condition, regardless of its nature and origin, is indicated by a resting heart pulse rate that deviates from the normal resting rate and a maximum heart pulse rate obtainable by physical exertion that deviates from the normal maximum rate, i.e., compromised range and flexibility. At the outset of the program, the patient is tested to determine his initial heart pulse range extending between his resting and maximum heart pulse rates to provide a base line for the program. In the course of the program, the patient whose heart beat is continuously monitored while exercising, undergoes a series of exercise-relaxation cycles. During each cycle, the exercising patient expends a surge of energy giving rise to a high pulse peak rate, the patient then relaxing to complete the cycle. This energy surge induces in the patient's heart a pendulum effect, causing the pulse rate to swing down from the peak rate to a resting rate below that in the initial range. The temporal conditions under which the program is conducted and its duration are such as to bring about a progressive rise in the maximum pulse rate attainable by the patient and to expand his range and increase the flexibility whereby at the conclusion of the program, the patient's maximum heart pulse rate and resting pulse rate approach those of an individual free of the abnormal condition.
Patent CA-2240499-A1 (CA)
Title: Technologie d'identification de marqueurs en fonction de la taille
Inventor: BUYSSE JERRY M
IPC: C12N15/10
Filed: 1996-12-20
Abstract: L'invention concerne un procédé pour identifier une cellule ou une souche de cellules contenant une mutation dans un gène jouant un rôle dans la croissance. Ce procédé comprend les étapes consistant à former un ensemble marqué de souches contenant plusieurs membres, chaque membre de l'ensemble contenant un fragment d'ADN exogène d'une longueur définie, intégrée avec stabilité dans le chromosome du membre. La longueur définie de chaque membre diffère de la longueur définie des autres membres. Ce procédé consiste également à soumettre l'ensemble marqué de souches à une mutagénèse de manière à obtenir des mutants à partir de chaque membre de l'ensemble de souches, et à introduire les souches mutantes dans un environnement de croissance pendant un laps de temps suffisant pour la croissance d'une souche n'ayant pas subi de mutation. Il consiste ensuite à déterminer les souches qui présentent une croissance réduite par rapport à une souche n'ayant pas subi de mutation, en déterminant la présence et la taille des fragments d'ADN exogènes les uns par rapport aux autres, à l'aide de la polymérase en chaîne et de l'électrophorèse sur gel de polyacrylamide/agarose.
Patent CA-2241239-A1 (CA)
Inventor: DERY PIERRE D P
IPC: B43L1/00
Filed: 1998-07-27
Abstract: La présente invention consiste en un casse-tête conçu de telle sorte que l'utilisateur puisse créer lui-même, en partie ou en totalité, l'image ou le dessin représenté. II est d'usage courent de produire des casse-tête sur lesquels apparaît une image. La présente invention consiste en un casse-tête spécialement conçu pour que l'utilisateur puisse y créer lui-même un dessin ou une image. L'utilisateur peut ensuite détacher les pièces du casse-tête. Par la suite, celui qui a créé le dessin, ou une outre personne, pourra recréer le dessin en assemblent les pièces du casse-tête. Grâce à la présente invention, l'utilisateur peut conserver son dessin sur le casse-tête ou l'effacer afin de créer un nouveau dessin. Avec le présente invention, le casse-tête peut être encastré dans un cadre (ou support), de telle sorte que le tout tient en place lorsque l'utilisateur y dessine ses oeuvres. Avec la présente invention, le niveau de difficulté peut varier de façon quasi illimitée selon le format, la forme et le nombre de pièces du casse-tête. Un casse-tête relativement facile constitue un jouet éducatif permettant à des enfants d'âges variés de créer eux-même leur casse-tête. Un casse-tête d'un niveau relativement difficile devient un jeu sur lequel les utilisateurs (soit des enfants plus vieux, soit des adolescent-e-s, soit pour des adultes de tous les âges) doivent eux-mêmes créer le dessin.
Patent CA-2241634-A1 (CA)
Inventor: BROWN JEFF
IPC: H04L29/06
Filed: 1998-06-22
Abstract: A system for disseminating information over a wide area network includes a central caching unit for storing data to be made available over the wide area ne twork. Local access give users access to the wide area network. Distributed caching uni ts associated with the local access nodes for store cacheable material. A satellite communications system establishes satellite communications between the central c aching unit and the local caching units for the transfer of cacheable material from the central caching unit to the local units. A router at the local access nodes routes packe ts from users to a destination address. The router includes local routing tables containing th e addresses of material cached at the associated local node and responds to routing requests for locally cached material by directing the requests to the local cache.
Patent CA-2242737-A1 (CA)
Title: Method of universal gravity heat exchanger, evaporator and condenser systems
Inventor: IGWE GODWILL M
IPC: F28F1/32
Filed: 1998-08-12
Abstract: Fluid in heat exchanger with flamed tubes in forced through the tubes to circulate around the horizontal tubes and forced out at the end of the tube.  Without external propelling power, some of the fluid will settle in the horizontal tubes. This is especially the case in phase transformation of fluid. This posses problems when there is no external propelling power. The present invention solves this problem when there is no external propelling power.     With reference to figure 1, the fluid enters at A and flows down by its own weight due to gravity and exit at B. There is no external power needed.
Patent CA-2243035-A1 (CA)
Inventor: TOMPKINS TED L
IPC: B62D53/08
Filed: 1998-07-13
Abstract: An apparatus for acting as a shock absorber for a truck towing a vehicle mated with a fifth-wheel, or a gooseneck, hitch.          A fifth-wheel, or gooseneck, trailer has members extending away from the trailer bed and converging.   A cylindrical housing, having a longitudinal axis aligned substantially perpendicular to the bed of the trailer, is attached to the members at the end where they converge.  A kingpin, having a fifth-wheel, or gooseneck, connector, is coaxially mounted in the housing.  A lever, having a fee end, extends from the kingpin over the rear of the truck.  A resilient means, extending between the free end and the rear of the truck, bias the rear of the truck toward the free end.  With this structure as the distance between the free end and the rear of the truck increases, additional bias is place on the rear of the truck tending to raise the rear of the truck.          The resilient means thus acts as a shock absorber.
Patent CA-2243414-A1 (CA)
Inventor: UENO SHOZO
IPC: G05D23/13
Filed: 1998-07-20
Abstract: An object of the present invention is to provide a bottom bypass structure of a thermostat device enabling it possible to stably operate a valve element, to prevent the overshooting and hunting and to reduce in sizing of the thermostat device. The structure to form a bypass channel to bypass a circulating fluid in the lower reaches of the valve element opening and closing the circulation channel.
Patent CA-2243965-A1 (CA)
Title: Laundry additive compositions including dispersible polyolefin and method for using same
Inventor: MASSCHELEIN AXEL
IPC: C11D3/37
Filed: 1997-01-29
Abstract: Laundry additive compositions and methods for their use are provided. The compositions include a dispersible polyolefin, preferably polyethylene, and at least one compound selected from the group consisting of dye fixative agents, chelating agents, dye transfer inhibiting agents, chlorine scavenging agents, free radical scavenging agents, cellulase enzymes and mixtures thereof.  Preferably, the composition is a liquid composition added to the rinse cycle of a consumer laundry process or to a pre-treatment cycle before a wash cycle of a consumer laundry process.
Patent CA-2244674-A1 (CA)
Inventor: ENGH LAWRENCE D
IPC: G10L19/00
Filed: 1998-08-11
Abstract: This invention discloses an integrated circuit for processing an audio signal of a message. The integrated circuit comprises a record circuit, an analog storage circuit, and a playback circuit. The record circuit is coupled to receive the audio signal and generates a filtered signal. The analog storage circuit is AC-coupled to the record circuit for storing the filtered signal. The playback circuit is coupled to the analog storage circuit for retrieving a stored signal in the storage circuit.
Patent CA-2244934-A1 (CA)
Title: Modular fiber-reinforced composite structural member
Inventor: SEIBLE FREIDER
IPC: E04C3/44
Filed: 1997-02-05
Abstract: A concrete-filled fiber-reinforced structural member (100) is provided comprising a concrete core (105) encased in a lightweight fiber-reinforced composite shell (103) formed by winding polymer impregnated high-strength filaments (107, 109). The fibers are arranged for optimal strength and may be tailored for a specific requirement. The shell structure (103) is durable, chemically inert, and adaptable to a variety of civil engineering applications. A plurality of composite structural members (100) can be connected via various connectors (301, 402, 409, 411) to form complex space frame structures (601, 701) such as industrial support structures, bridges, buildings and the like.
Patent CA-2245783-A1 (CA)
Title: Proteines et acides nucleiques fhit et procedes afferents
Inventor: CROCE CARLO M
IPC: C12Q1/68
Filed: 1997-02-07
Abstract: La présente invention concerne des séquences de nucléotides de gènes FHIT, des séquences d'acides aminés de leurs protéines codées, ainsi que leurs dérivés et analogues, et des anticorps dirigés contre eux. La séquence de gènes FHIT est mutée lors de maladies où l'on assiste à une surprolifération cellulaire, notamment dans le cas d'affections malignes des voies digestives. Cette invention concerne également l'utilisation des gènes FHIT et de leurs protéines codées, en qualité de réactifs diagnostiques et thérapeutiques dans la détection et le traitement d'états pathologiques associés à une surprolifération cellulaire.
Patent CA-2248447-A1 (CA)
Inventor: MCCALL JAMES M
IPC: B22F1/10
Filed: 1998-09-22
Abstract: Boric acid-containing lubricants are disclosed which consist essentially of boric acid and at least one other powder  metallurgy  lubricant  and provide  a  synergistic free-flowing composition.   There are also provided novel compositions  of  matter  for  forming  sintered    metal components comprising a mixture of sinterable,  powdered metal and the said lubricants.
Patent CA-2248496-A1 (CA)
Inventor: CRUDELE JOANNE
IPC: A61K8/34
Filed: 1998-09-30
Abstract: A method and a hair care composition with stylability are provided for improving conditioning and stylability. The composition combines phytantriol, L-arginine, and silk amino acids.