baber/WOPTO huggingface dataset:
Patent DE-69535460-T2 (DE)
Inventor: CHEN XIAN
IPC: C07K14/435
Filed: 1995-04-12
Granted: 2008-01-03
Abstract: The present invention provides novel therapeutic compositions and multipeptide formulations of peptides and modified peptides of Group I and Group II Der p and Der f derived protein allergens. Such novel therapeutic compositions and multipeptide formulations are the result of a preformulation scheme to develop an optimized drug product for therapeutic treatment of humans suffering from allergy to house dust mite allergens. The Der p and Der f peptides and modified peptides in accordance with the invention possess certain unique characteristics which render them particularly suitable for drug product formulation. Therapeutic compositions and multipeptide formulations of the invention have been optimized to accommodate and maintain the unique characteristics of the peptides and modified peptides derived from house dust mite protein allergens and at the same time provide maximum therapeutic effect when used in therapeutic regimens for the treatment of house dust mite allergy in humans. The invention further provides novel modified peptides derived from Der p I and Der p II protein allergens.
Patent DE-69535466-T2 (DE)
Inventor: KNIPE DAVID
IPC: C07K14/03
Filed: 1995-01-09
Granted: 2008-01-03
Abstract: A herpesvirus vaccine comprising a mutated herpesvirus suspended in a pharmaceutically acceptable carrier. The mutated herpesvirus is capable of infecting cells of the mammal to be vaccinated, but incapable of completing a replicative cycle, and it is capable of eliciting a protective immune response in that mammal. The mutated herpesvirus is also capable of treating immunomodulatory or immunoregulatory diseases. The mutation occurs in at least one gene encoding a protein essential for replication of the virus, so that the mutation renders the virus replication defective.
Patent DE-69600900-T2 (DE)
Inventor: JOANICOT MATHIEU
IPC: C08G18/72
Filed: 1996-04-17
Granted: 1999-04-15
Abstract: Method is claimed for preparation of latex of particles of (co)polymers with size = 10-1000nm; the particles having accessible acid function content = 0.2-1.2 milliequivalent gram<-1> solid material, and accessible alcohol function content = 0.3-1.5 milliequivalent gram<-1> solid material. Method involves polymerisation in (micro)emulsion of (mixture of) non-ionic monomer(s) do not have alcohol functions and (mixture of) acidic monomer(s) with free acid function or one of its salts.
Patent DE-69611059-T2 (DE)
Inventor: INADA GENJI
IPC: B41J2/14
Filed: 1996-06-19
Granted: 2001-05-10
Abstract: A method for manufacturing an ink jet head comprises a first step of arranging on a substrate a passage molding material to form ink paths conductively connected to discharge ports for discharging ink, a second step of arranging on the substrate an edge portion molding material in the vicinity of the passage molding material, a third step of arranging on the substrate a wall formation material to cover the passage molding material and the edge portion molding material, and a fourth step of forming the paths with the wall formation material by removing the passage molding material from the substrate. With this method, it is possible to manufacture an ink jet head having an ink chamber and nozzles, which are configured substantially the same as the molding members, without creating cracks and other defects that are liable to occur on the extruded corners of the passage molding material with respect to the substrate when the conventional technique is applied. <IMAGE>
Patent DE-69612513-T2 (DE)
Inventor: RANDELL FRANCIS
IPC: F16F1/371
Filed: 1996-12-17
Granted: 2002-04-18
Abstract: An elastomeric spring (10) comprises a body (11) of elastomeric material which extends between a pair of opposed end regions (12, 13) whereby compression forces acting in a first direction (16) on said end regions are resisted by compression of the elastomeric body, the body (11) of elastomeric material being of a substantially symmetrical shape as considered in cross section about a major axis (16) of the spring extending in said first direction, and substantially hollow in the vicinity of at least one (13) of said end regions, said body (11) of elastomeric material being of progressively increasing external cross-sectional dimension over a first part (21) of the length of the body extending from a first (32) of said end regions and of progressively decreasing external cross-sectional dimension over a second part (22) of the length of the body extending to a second (13) of said end regions, a substantially inextensible reinforcement member (17) embedded in and bonded to said body (11) of elastomeric material at a position between said first and second parts (21, 22) of the length of the body, the body of elastomeric material being hollow over a distance which extends, in said first direction (16), from said at least one (13) of said end regions to beyond the position at which said reinforcement member (17) lies between the end regions (12, 13), and the body of elastomeric material being of progressively increasing external cross-sectional dimension over a part (24) of the length of the body extending from the reinforcement member (17) to said second part (22).
Patent DE-69612797-T2 (DE)
Inventor: BIAGINI PAOLO
IPC: C07C271/02
Filed: 1996-07-04
Granted: 2001-09-13
Abstract: Process for the preparation of N-alkyl substituted metal carbamate solutions characterized in that a water solution of the salt of the metal of which the corresponding carbamate is to be obtained, is reacted with an organic solution, basically consisting of an aprotic solvent and a secondary amine, saturated with carbon dioxide. The above solutions can be used as catalysts in polymerization reactions of unsaturated monomers or for supporting metals on inorganic oxides.
Patent DE-69613365-T2 (DE)
Inventor: GIERSKCKY ERIK
IPC: A61K41/00
Filed: 1996-03-08
Granted: 2002-05-02
Abstract: PCT No. PCT/GB96/00553 Sec. 371 Date Dec. 5, 1997 Sec. 102(e) Date Dec. 5, 1997 PCT Filed Mar. 8, 1996 PCT Pub. No. WO96/28412 PCT Pub. Date Sep. 19, 1996The invention provides a pharmaceutical compositions comprising a compound of formula I:R22N-CH2COCH2-CH2CO-OR1(I)wherein, R1 and R2 have any of the values defined in the specification; or a salt thereof; and a pharmaceutically acceptable carrier or excipient. The invention also provides a method for the diagnosis or photochemotherapeutic treatment of disorders or abnormalities of external or internal surfaces of the body using such compounds or salts.
Patent DE-69620363-T2 (DE)
Inventor: SUGAWA TADASHI
IPC: C12P13/00
Filed: 1996-06-19
Granted: 2002-11-21
Abstract: A process for producing optically active 1-halo-3-amino-4-phenyl-2-butanol derivatives from optically active 1-halo-3-amino-4-phenyl-2-butanone derivatives stereoselectively in a high yield by bringing the butanone derivatives into contact with microorganisms.
Patent DE-69623952-T2 (DE)
Inventor: LU PRISCILLA MARILYN
IPC: H04W36/14
Filed: 1996-05-03
Granted: 2003-08-07
Abstract: a method for facilitating cellular communication for and among a plurality of native cellular handsets in a hybrid cellular communication network that has a cellular exchange subsystem and a private mobile-services switching center. In this embodiment, the cellular exchange subsystem is coupled to a public cellular network, and the native cellular handsets represent handsets that subscribe to the hybrid cellular communication network. The hybrid cellular communication network further facilitates cellular communication between a non-native cellular handset and the public cellular network, with the non-native cellular handset and the public cellular network, with the non-native cellular handset being a cellular handset that does not subscribe to the hybrid cellular communication network. In this embodiment, the method includes the steps of receiving access request data, using a cellular exchange subsystem, and ascertaining whether the access request data originates from one of the plurality of native cellular handsets or from the non-native cellular handset. If the access request data originates from the one of the plurality of native cellular handsets, the method then passes data relating to the access request to the private mobile-services switching center for completing a first call path from the one of the plurality of native cellular handsets. On the other hand, if the access request data originates from the non-native cellular handset, the method passes data relating to the access request data to the public cellular network for completing a second call path between the non-native cellular handset and the public cellular network.
Patent DE-69624507-T2 (DE)
Inventor: MAEKIPEURA PETRI
IPC: C07C51/567
Filed: 1996-12-12
Granted: 2003-06-12
Abstract: In the preparation of alkenyl succinic anhydride (ASA) from an olefinically unsaturated hydrocarbon and a maleic anhydride, additives are used in the preparation reaction in order to improve the yield of the product and to reduce side reactions. According to the present invention, quinone and hydroquinone derivatives as well as dialkyl sulfoxides and transition-metal acetylacetonate have such properties. The amounts to be added are approx. 0.01-2 mol % of the amount of maleic anhydride. The olefin is preferably a straight-chain  alpha -olefin or a straight-chain or branched internal olefin having a chain length of 6-20 carbon atoms. The olefin may also be a polyolefin, in which case the preferred molecular weight is 900-1500. The preparation process may be of the batch type or the semi-batch type, and the maleic anhydride and the additive may be added in several batches or as a continuous feed which may be even or variable. The ASA obtained by the process may be used in particular as an additive in foods, for hydroxy sizing of paper, or as a dispersing agent in lubricants.
Patent DE-69630874-T2 (DE)
Inventor: HILLIAHO ERKKI
IPC: E06B3/46
Filed: 1996-01-29
Granted: 2004-09-02
Abstract: The invention relates to a mounting assembly for a sheet-like piece, particularly a balcony glazing, for covering partially or entirely openings in the exterior of the building or the like. The mounting assembly comprises a guide arrangement (1, 2) or the like to be fixed to the horizontal edge of the opening to be covered and to support one or several sheet-like pieces, such as a balcony glass. The guide arrangement (1, 2) of the mounting assembly is at least partly pre-installed in a stationary manner in the exterior of the building or the like, wherein the mounting assembly can be used, when necessary, for mounting said at least one plate-like piece in said opening.
Patent DE-69702454-T2 (DE)
Inventor: KING REGINALD ALFRED
IPC: G06K19/07
Filed: 1997-08-20
Granted: 2001-03-08
Abstract: A security device and a security system incorporating such a device comprises a portable secure object which includes a unit for storing information, a unit for storing a voice biometric signal or a signal indicative thereof, and an integral microphone. The microphone generates the voice biometric signal during a registration procedure, and subsequently derives a further voice biometric signal for comparison with the generated voice biometric signal for subsequent interrogation purposes.
Patent DE-69703004-T2 (DE)
Inventor: GIAMELLO BRUNO
IPC: A23G1/20
Filed: 1997-06-16
Granted: 2001-06-07
Abstract: The cutting apparatus includes an ultrasound cutting element (2) associated with a drive mechanism (4) which enables the rate of advance of the cutting element (2) through the product (A) being cut to be varied selectively and locally. The preferred application is for cutting layered food products (A). <IMAGE>
Patent DE-69705870-T2 (DE)
Inventor: LIIMATAINEN JARI ILMARI
IPC: C22C38/38
Filed: 1997-01-13
Granted: 2002-04-11
Abstract: The invention relates to the field of powder metallurgy. A steel is disclosed, which is compacted from a powder mixture by means of pressure and heat, its microstructure arising mainly from two components, the first of which being austenitic (e.g., Hadfield manganese steel) and the second being an essentially martensitic component rich in hard precipitates. The austenitic microstructure is more ductile than the martensitic, and it effectively prevents the propagation of microscopic cracking. Thus, the material is suitable for use in wear parts subjected to strong forces, as in, e.g., stone crushers. <IMAGE>
Patent DE-69707919-T2 (DE)
Inventor: ALBERT LUC
IPC: H01M4/68
Filed: 1997-02-13
Granted: 2002-04-25
Abstract: A lead alloy for battery grids is disclosed. The lead alloy contains calcium with a relative concentration by weight of between 0.05% and 0.12%; tin with a relative concentration by weight of less than 3%; aluminum with a relative concentration by weight of between 0.002% and 0.04%; and barium comprising a relative concentration by weight of less than 0.02%.
Patent DE-69708305-T2 (DE)
Inventor: KAYEROD HELLE
IPC: A61M25/08
Filed: 1997-09-18
Granted: 2002-05-02
Abstract: A urinary catheter assembly comprises a urinary catheter (1) having on at least a part of its surface a hydrophilic surface layer (6) intended to produce a low-friction surface character of the catheter by treatment with a liquid swelling medium prior to use of the catheter and a catheter package (7) having a cavity (11) for accommodation of the catheter (1).  The package (7) includes a compartment (12) having walls of a gas impermeable material and accommodating said liquid swelling medium or a catheter pretreated therewith for long time preservation of said low-friction surface character and provision of a ready-to-use catheter assembly.
Patent DE-69714023-T2 (DE)
Inventor: BURK M
IPC: A61K31/557
Filed: 1997-02-20
Granted: 2003-03-13
Abstract: The present invention provides cyclopentane heptanoic acid, 2 heteroaryl alkyl or alkenyl derivatives which may be substituted in the 1-position with hydroxyl, alkyloxy, amino and amido groups, e.g. 1-OH cyclopentane heptanoic acid, 2 heteroarylalkenyl derivatives. In particular, these derivatives are 7-[5-hydroxy-2-(heteroatom-substituted hydroxyhydrocarbyl)-3-hydroxycyclopentyl] heptanoic or heptenoic acids and amine, amide, ether, ester and alchohol derivatives of said acids wherein one or more of said hydroxy groups are replaced with an ether group. These compounds are potent ocular hypotensive and are particularly suited for the management of glaucoma. Moreover, the compounds of this invention are smooth muscle relaxants with broad application in systemic hypertensive and pulmonary diseases; with additional application in gastrointestinal disease, reproduction, fertility, incontinence, shock, inflammation, immune regulation, disorder of bone metabolism, renal dysfunction, cancer and other hypoproliferative diseases.
Patent DE-69714841-T2 (DE)
Inventor: KAWAMOTO ISAO
IPC: A61K31/403
Filed: 1997-04-25
Granted: 2003-05-28
Abstract: A 1-methylcarbapenem compound represented by the following formula: <CHEM> Äwherein R<1> represents a hydrogen atom or a lower alkyl group, R<2> represents a hydrogen atom or a lower alkyl group, R<3> represents a hydrogen atom, a lower alkyl group, a lower alkyl group which has a substituent, a cycloalkyl group or a group of formula -C(=NH)R<4> (in which R<4> represents a hydrogen atom, a lower alkyl group or an amino group)Ü; or a pharmacologically acceptable salt or derivative thereof. ÄAdvantagesÜ The 1-methylcarbapenem compounds of the present invention exhibit excellent antibacterial activity and are therefore effective as a preventive or remedy of infections.
Patent DE-69717814-T2 (DE)
Inventor: LARSSON ROLF
IPC: B23K20/12
Filed: 1997-06-18
Granted: 2003-09-11
Abstract: A plant for friction stir welding, comprising a welding probe, a drive unit driving the welding probe, a work table supporting the workpiece or workpieces to be welded, and at least one clamping means for clamping the workpieces to one another or to the work table, or the workpieces to the work table, respectively, during the welding operation. The plant likewise comprises a milling tool.
Patent DE-69719508-T2 (DE)
Inventor: NUGTEREN WILLEM
IPC: B23K11/31
Filed: 1997-05-05
Granted: 2004-02-19
Abstract: The invention relates to a pneumatic operating cylinder for operating a tool in linear movement, wherein the operating cylinder comprises: a working cylinder which is divided by at least one piston arranged therein into a least a first and a second cylinder space, wherein the piston is connected to a piston rod onto which the tool is fixed; and control means for controlling the movement of the piston, wherein the control means are connected to a compressed air feed channel and to an air discharge channel, wherein the control means are adapted to connect the compressed air feed channel in a first position to the first cylinder space and to connect the second cylinder space to the air discharge channel via a choke valve, wherein the control means comprise an auxiliary valve which connects the second cylinder space to the discharge channel when the pressure in the second cylinder chamber is less than a predetermined factor times the pressure in the first cylinder chamber; and wherein the control means are adapted to connect the first cylinder space in a second position to the air discharge channel and to connect the second cylinder space to the compressed air feed channel.
Patent DE-69727068-T2 (DE)
Inventor: HAUGAN OLAV
IPC: B65D19/00
Filed: 1997-10-23
Granted: 2005-02-17
Abstract: A pallet leg (1) and a pallet respectively comprises and is provided with respectively as legs a punched and grooved and/or perforated blank, made of corrugated paper-board having a transversal wave direction. The blank is folded up in a supporting and bracing way. According to the invention brace legs (9) extend from the against each other abutting areas of the top surfaces (7) of a leg (1), obliquely downwards and into the corner area between a base surface (2) and a wall (5), in a hypotenuse-like, a pressure arch-forming way, to which brace legs in a flat position against the inner side of the flanks (5) with an inherent elasticity, due to the structural design, abutting support legs are connected. In order to maintain the folded-up application condition of the leg and the fixing of said pressure arch the top surfaces (7) are designed to be fastened to the bottom surface of an upper pallet tray (26), which jointly with an arbitrary number of legs constitutes a complete pallet (25).
Patent DE-69737210-T2 (DE)
Inventor: ROBERTS NEIL
IPC: F25B1/00
Filed: 1997-11-28
Granted: 2007-11-08
Abstract: A non-azeoptropic refrigerant composition having a vapour pressure at -20° C. of from 70 to 190 kPa (0.7 to 1.9 bar), at +20° C. of from 510 to 630 kPa (5.1 to 6.3 bar) and at +60° C. of from 1620 to 1740 kPa (16.2 to 17.4 bar), which composition comprises:(a) 1,1,2,2-tetrafluoroethane (R134), 1,1,1,2-tetrafluoroethane (R134a), difluoromethoxytrifluoromethane (E125) or a mixture of two or more thereof, in an amount of from 60 to 990 by weight, based on the weight of the composition;(b) from 1 to 10% by weight, based on the weight of the composition, of an unsubstituted hydrocarbon of the formula CnHm in which n is at least 4 and m is at least 2n-2; and,(c) up to 39% by weight, based on the weight of the composition, of a vapour pressure depressant.
Patent DE-69805903-T2 (DE)
Inventor: PREVOT GERARD
IPC: E05B63/06
Filed: 1998-03-31
Granted: 2003-01-30
Abstract: The locking mechanism has an adjustable bolt (7) for a sliding door, window or similar with a bolt carrier (4). The carrier has at least one slot (5) to receive the shank (6) of the bolt, which has at least one hook (8a, 8b). The bolt carrier is designed to slide transversely relative to the slot to enable the hook(s) to engage with or disengage from a catch plate on the fixed surround of the door or window. The bolt is made so that it can be moved lengthwise in the slot to adjust its position relative to the catch plate, and it is fixed in position by means of an aperture (21) extending in the same direction as the slot and a locking screw (16) which engages with the edges of the aperture. The bolt can have either one aperture in line with its lengthwise axis or two apertures lying symmetrically relative to the axis.
Patent DE-69807485-T2 (DE)
Inventor: SMELLIE S
IPC: G06F17/50
Filed: 1998-06-23
Granted: 2003-04-10
Abstract: According to an embodiment of the present invention, a method for determining a conformation for a molecular structure is provided. The method includes a variety of steps such as computationally decomposing the molecular structure into fragments. A step of normalizing each of the fragments in order to form normalized fragments is also included. The step of determining at least one or possibly many conformers for each normalized fragment is included in the method. Finally, the step of combining at least a first conformer and a second conformer in order to derive the molecular structure is performed. Other conformers may also be included in the combination. Some embodiments will also include a step of searching for one or more conformers fragments in a library. If the fragment is found in the library, then its corresponding conformers are read from the library. Otherwise, the method includes an additional step of storing the fragment and conformer information it produces in the determining step into the library for subsequent analyses. Select embodiments according to the invention can produce low energy conformers by resolving strain and torsion within chemical bonds between atoms in the fragments.
Patent DE-69808514-T2 (DE)
Inventor: O'DONNELL SYLVIE
IPC: B43K1/08
Filed: 1998-12-22
Granted: 2003-01-30
Abstract: There is disclosed a cemented carbide containing tungsten carbide, titanium carbide, nickel, molybdenum and chromium. The composition of the materials provides a good resistance to corrosion as well as high hardness and wear resistance. These properties are particularly interesting for the manufacture of pen balls. Ball-point pen balls made with these materials will have steady writing characteristics over a long period of time. This material is particularly suitable when water-based inks are used, because these inks are far more common than oil-based inks.
Patent DE-69812699-T2 (DE)
Inventor: CHRISTENSEN RUST
IPC: C03B3/02
Filed: 1998-12-02
Granted: 2004-03-11
Abstract: Man-made vitreous fibres having a content of aluminium of at least 14 % are produced by providing a charge of raw mineral material which contains ferro-chromium slag, preferably at least 5 % by weight ferro-chromium slag, in a furnace, melting the charge in the furnace to form a melt and fiberising the melt to form fibres.
Patent DE-69824976-T2 (DE)
Inventor: BIEHL BOELE
IPC: A23G1/02
Filed: 1998-10-15
Granted: 2004-12-16
Abstract: The invention relates to a novel low-flavor cocoa, a method for its production and a use thereof. The novel low-flavor cocoa is obtainable from unfermented cocoa beans by a two step process. In the first step the unfermented beans are treated to destroy the cellular and subcellular structures and then in a second step they are subjected to an oxidation treatment. This method suppresses the formation of flavor and hence low-flavor cocoa is obtained which is e.g. useful as substitute for cocoa butter in the manufacture of chocolate and for the compensation of variations in the flavor intensity of untreated cocoa.