baber/WOPTO huggingface dataset:
Patent CA-2880196-A1 (CA)
Inventor: YANG SHENGYONG
IPC: C07D487/04
Filed: 2013-03-05
Abstract: The invention belongs to the technical field of organic synthetic drugs, and particularly relates to a pyrazolopyrimidine derivative and a preparation method and medical uses thereof. The invention provides a new pyrazolopyrimidine derivative mainly having position 4 substituted, i.e., position substituted by Y in formula I.  The pyrazolopyrimidine derivative of the invention has a structural formula I  as follows: (see formula I) The invention provides a new pyrazolopyrimidine derivative and a simple, efficient and low-cost preparation method thereof. The pyrazolopyrimidine derivative of the invention has good inhibitory activity for multiple kinases, has inhibitory action on multiple solid tumors, leukemia and autoimmune diseases, provides a new effective choice for preparation of kinase inhibitors, medicines for autoimmune diseases, angiogenesis inhibitors and antitumor drugs, and has good application prospect.
Patent CA-2880498-A1 (CA)
Inventor: HARVEY ANDREW
IPC: A61K31/44
Filed: 2013-08-01
Abstract: The present invention relates to chemical compounds of formula (I), with the substituents as described in the specification, useful in the positive modulation of the alpha 7 nicotinic acetylcholine receptor (a7 nAChR). The invention also relates to the use of these compounds in the treatment or prevention of a broad range of diseases in which the positive modulation of a7 nAChR is advantageous, including neurodegenerative and neuropsychiatric diseases and also neuropathic pain and inflammatory diseases.
Patent CA-2881037-A1 (CA)
Inventor: PAVOL JANIK
IPC: G06T7/00
Filed: 2013-05-13
Abstract: The method of description of the points (12) of the object (11) from the object space (1), characterized by that for each point (12) of the object (11) of the object space (1) displayed on the graticule (35) of the shooting device (3), information about the point distance (I) from tire shooting device (3) is registered and this information is then stored to each point (36) of the graticule (35) of image as additional data. Connection for implementation of the method of description of the points (12) of the object (11) from the object space (1) according to previous claims, covering the shooting device (3) substance of Which is that the shooting system (2) consists of at least two shooting devices (3) connected to the inputs of CPU (4) central control unit, which includes a block of software applications (5) and a block of computing module (6) with evaluation software, whereas communication of the block of software applications (5) and the block of calculation module (6) with the evaluation software with CPU (4) occurs via data buses, whereas the CPU (4) outputs are connected both on the block of internal memory (7) and/or removable memory and the block of online outputs (8).
Patent CA-2881152-A1 (CA)
Title: Initiating production of clathrates by use of thermosyphons
Inventor: BALCZEWSKI JOHN THOMAS
IPC: E21B43/24
Filed: 2013-08-13
Abstract: A method and system for initiating hydrocarbon production from a reservoir (100) are provided. This method and system utilize thermosyphons. The system and method utilize one or more sealed, elongated, hollow tubular containers supported in earth in a geothermal heat zone below the reservoir and extending upwardly therefrom into the reservoir. The containers comprise (a) a bottom portion (400) in the geothermal heat zone below the reservoir; (b) a top portion (300) within the reservoir; and (c) being partially filled with a liquid (200) that evaporates in the bottom portion forming a vapor and transferring heat via convective flow of the vapor to the top portion, the heat being dissipated at the top portion into the surrounding reservoir as the vapor condenses back into liquid and flows downward to the bottom portion. The reservoir can be a clathrate reservoir.
Patent CA-2883591-A1 (CA)
Inventor: KIKKERT MARJOLEIN
IPC: C12N7/00
Filed: 2013-09-25
Abstract: The present invention relates to replication-competent Arteriviruses having a decreased DUB/deISGylating activity due to a mutation in the PLP2 domain of the non-structural protein nsp2, to their use as a medicament, their use as a vaccine and in prophylaxis, to vaccines comprising such Arteriviruses and to Arteriviral PLP2-ubiquitin complexes.
Patent CA-2883852-A1 (CA)
Inventor: AHMED WILLIAM
IPC: G16H20/30
Filed: 2013-09-04
Abstract: Embodiments provide physiological measurement systems, devices and methods for continuous health and fitness monitoring. A lightweight wearable system is provided to collect various physiological data continuously from a wearer without the need for a chest strap. The system also enables monitoring of one or more physiological parameters in addition to heart rate including, but not limited to, body temperature, heart rate variability, motion, sleep, stress, fitness level, recovery level, effect of a workout routine on health, caloric expenditure. Embodiments also include computer-executable instructions that, when executed, enable automatic interpretation of one or more physiological parameters to assess the cardiovascular intensity experienced by a user (embodied in an intensity score or indicator) and the user's recovery after physical exertion (embodied in a recovery score). These indicators or scores may be displayed to assist a user in managing the user' s health and exercise regimen.
Patent CA-2883877-A1 (CA)
Inventor: GOODWIN GEORGE B
IPC: E06B3/673
Filed: 2013-07-12
Abstract: An insulating unit includes a first spacer frame between first and second sheets, e.g. glass sheets, and a second spacer frame between the second sheet and a third sheet. A first surface of the first spacer frame is adhered to inner surface of the first sheet, and an opposite second surface of the first spacer frame is adhered to a first surface of the second sheet, by a moisture impervious adhesive layer. A first outer surface of the second spacer frame is adhered to a second surface of the second sheet, and an opposite second outer surface of the second spacer frame is adhered to an inner surface of the third sheet, by the adhesive layer. The first spacer frame and the second spacer frame have an offset of greater than zero.
Patent CA-2886439-A1 (CA)
Inventor: CLEARY MICHAEL
IPC: C09D5/18
Filed: 2013-09-27
Abstract: La présente invention concerne un système de marque conçu pour une application à des surfaces et fonctionnant à de hautes températures. Le système de marque comporte une marque et un support élastique en température susceptible de fixer le système de marque sur une surface à haute température. Le support contient une matrice inorganique permettant de fixer la marque à une surface. La marque comporte une empreinte destinée à rendre la marque unique. Le système de marque contient en outre un matériau indicateur conçu pour indiquer la présence de la marque. La présente invention concerne également une composition contenant le système de marque, ainsi que des moteurs, des systèmes d'échappement et/ou des convertisseurs catalytiques ou d'autres surfaces fonctionnant à de hautes températures et présentant une surface imprégnée du système de marque.
Patent CA-2886793-A1 (CA)
Title: Determining a confidence value for a fracture plane
Inventor: LIN AVI
IPC: G01V1/40
Filed: 2013-08-22
Abstract: Systems, methods, and software can be used to determine a confidence value for a fracture plane. In some aspects, a subset of microseismic events associated with a fracture treatment of a subterranean zone are selected. Confidence in associating the selected subset of microseismic events with a common fracture plane is determined. The confidence can be determined, for example, based on the number of microseismic events in the subset, a location uncertainty for each microseismic event in the subset, a moment magnitude for each microseismic event in the subset, a distance between each microseismic event and a fracture plane fitted to the microseismic events, an orientation of the fracture plane fitted to the microseismic events, or a combination of these and other factors.
Patent CA-2888143-A1 (CA)
Inventor: HUNTER CLIFFORD
IPC: A01H4/00
Filed: 2013-11-04
Abstract: The present disclosure provides for novel methods to facilitate germplasm improvement activities through the use of embryo sampling. A method comprising obtaining at least one isolated embryo, excising a piece of scutellum or cotyledon tissue from the at least one isolated embryo such that the germination potential of the embryo is not significantly reduced, and analyzing the scutellum or cotyledon tissue sample(s) for the presence or absence of one or more characteristics indicative of at least one genetic trait is provided.
Patent CA-2889012-A1 (CA)
Title: High-rate reactor system
Inventor: COPPOLA EDWARD N
IPC: B01J19/24
Filed: 2013-10-22
Abstract: A process and system for upgrading an organic feedstock including providing an organic feedstock and water mixture, feeding the mixture into a high-rate reactor, wherein the mixture is subjected to heat and pressure, maintaining the heat and pressure to the mixture for a residence time of less than three minutes to cause the organic components of the mixture to undergo a reforming reaction resulting in the formation of high octane hydrocarbon products, cooling the hydrocarbon products at a rate sufficient to inhibit additional reaction and to enable recovering of process heat, and depressurizing the hydrocarbon products, and separating the hydrocarbon products for further processing. The process and system can include a device to convert olefinic byproduct gas to additional high-octane naphtha and/or heavier hydrocarbons by one of alkylation or oligomerization.
Patent CA-2889851-A1 (CA)
Inventor: MILLER THEODORE
IPC: H02H3/16
Filed: 2013-11-01
Abstract: A circuit interrupter (100) includes a first electrical conductor (105), a second electrical conductor (106), separable contacts (107), an operating mechanism (108) configured to open and close the separable contacts, and a trip circuit including a trip actuator (109) configured to cooperate with the operating mechanism to trip open the separable contacts. The circuit interrupter also includes a ground fault detection circuit (112,113) configured to sense a difference between currents through the first and second electrical conductors and to output an output signal based on the sensed difference, a power supply (115) configured to convert alternating current power from the first and second electrical conductors to a direct current power, and a processor (114) configured to receive the direct current power and the output signal. The processor is also configured to determine whether a characteristic of the power supply is present in the output signal and to control the trip circuit based on the determination.
Patent CA-2890390-A1 (CA)
Title: Article of footwear incorporating braided tensile strands
Inventor: FOLLET LYSANDRE
IPC: A43B1/04
Filed: 2014-01-14
Abstract: A branched braid member has a central braid portion and one or more tensile strands or small braids at either end of the central braid portion The branched braid member may be incorporated into a shoe upper.
Patent CA-2891842-A1 (CA)
Title: Dispositif et necessaire de prelevement d'echantillons
Inventor: CHING VICTORIA JESSICA
IPC: A61B17/42
Filed: 2013-11-27
Abstract: L'invention concerne des dispositifs et des procédés d'utilisation associés qui permettent de prélever un échantillon biologique lors d'une insertion dans un orifice humain. Le dispositif peut comprendre un élément corps, un élément d'insertion s'étendant à partir d'une extrémité de l'élément corps et une poignée reliée à l'autre extrémité de l'élément corps. Lors de la rotation de la poignée, une tige logée dans l'élément corps, ayant une extrémité de prélèvement située à une partie distale de celui-ci, s'étend d'une position rentrée vers une position étendue, de sorte que l'extrémité de prélèvement sorte d'une ouverture dans l'élément d'insertion. L'angle de l'élément corps par rapport à l'élément d'insertion peut être configuré pour un prélèvement d'échantillon vaginal à effectuer soi-même en position assise. L'extrémité de prélèvement peut être un tampon présentant une pluralité d'ailettes à moulinet dont le bord d'attaque est orienté de manière à recueillir l'échantillon biologique lorsque la tige est tournée dans une direction donnée.
Patent CA-2895739-A1 (CA)
Title: Mecanisme d'installation de roue
Inventor: OBEROI HARINDER
IPC: B60B29/00
Filed: 2015-06-25
Abstract: Un procédé et un appareil permettant dinstaller un ensemble bras de roue pour un véhicule autonome. Lensemble bras de roue peut être inséré dans une base du véhicule autonome depuis lextérieur de la base. Un certain nombre de fixations peuvent être installées à lextérieur de la base pour fixer lensemble bras de roue à la base du véhicule autonome.
Patent CA-2901724-A1 (CA)
Title: Amelioration apportee a l'uniformite de pneumatiques a l'aide d'estimations basees sur une convolution/deconvolution
Inventor: MAWBY WILLIAM DAVID
IPC: G01M17/02
Filed: 2013-03-29
Abstract: La présente invention concerne des systèmes et des procédés permettant d'améliorer l'uniformité d'un pneumatique à l'aide d'estimations de paramètres d'uniformité basées sur une convolution/déconvolution d'un pneumatique. Par exemple, la convolution peut être utilisée pour estimer une variation de force radiale à partir d'une ou de plusieurs mesures de paramètres d'uniformité, y compris des mesures de paramètres de faux-rond. La déconvolution peut être utilisée pour estimer un faux-rond à partir d'une ou de plusieurs mesures de paramètres d'uniformité, y compris des mesures de paramètres de variation de force radiale. Le paramètre d'uniformité estimé peut être estimé à partir des mesures de paramètres d'uniformité à l'aide d'un ou de plusieurs modèles. Le ou les modèles peuvent représenter un paramètre d'uniformité radiale estimé au niveau d'un point de mesure discret en tant que somme pondérée du paramètre d'uniformité radiale mesuré au niveau du point de mesure discret et d'un ou de plusieurs points de mesure sélectionnés à proximité du point de mesure discret. Les points mesure peuvent être sélectionnés sur la base de la longueur de la surface de contact du pneumatique avec le sol.
Patent CA-2910841-A1 (CA)
Inventor: VISHNIAC EPHRAIM MERIWETHER
IPC: G06F17/30
Filed: 2007-10-29
Abstract: A method for managing data includes receiving individually accessible data units, each identified by a key value and storing first and second sets of blocks of data, the first set generated by compressing data units and the second set generated by compressing data units received after storing the first set of blocks. The first and second sets of blocks are decompressed to recover data units from which their blocks were generated. The recovered data units are sorted according to an order for key values corresponding to the data units to generate a set of sorted data units. A third set of blocks is generated, some by compressing sorted data units. A screening data structure is provided that is associated with the stored blocks for determining a possibility that a data unit that includes a given attribute value was included in the data units from which the blocks were generated.
Patent CA-2913571-A1 (CA)
Inventor: MAILHOT FREDERIC
IPC: G06F21/45
Filed: 2015-12-01
Abstract: A method and apparatus to generate secure passwords without storing them anywhere
Patent CA-2913651-A1 (CA)
Title: Tool for wire tying and untying
Inventor: ROMERO ARAGUETE FRANCISCO
IPC: B21F15/04
Filed: 2014-06-03
Abstract: The invention concerns a tool for forming and releasing metal lashing, consisting of a resistant elongate body which defines between its end sections two tubular passages (1), which open out on the exterior through one of said end sections (2), at least and extends from the opposite end section in a coaxial shaft (6).
Patent CA-2915140-A1 (CA)
Inventor: SCHILLING PAUL CHRISTOPHER
IPC: F16L3/237
Filed: 2015-12-15
Abstract: Upper and lower P-clamps secured to a structure by a fastener, upper and lower legs attached to upper and lower annular clamp bodes of the P-clamps, the upper leg on top of the lower leg, and a support plate secured to the structure between the upper P-clamp and the structure. The fastener may be disposed through holes in the upper and lower legs.  Circular or rounded annular clamp bodies may secure articles therein and be attached to the upper and lower legs. A loop portion of the clamp body may be encased by an elastomeric sheath. Each of the upper and lower legs may include upper and lower flanges outside of the elastomeric sheath and extending away from upper and lower portions respectively of the loop portion. The upper and lower legs may be parallel or angled with respect to each other.
Patent CA-2916347-A1 (CA)
Inventor: KENDALL JOHN W
IPC: A01G27/02
Filed: 2015-12-28
Abstract: A plant growth assembly, comprising; a base portion, a plug portion, a liquid dispersal portion and a support portion, the base portion inserts into growth medium, earth and/or soil at least partially, plants are grown about the base portion periphery. The plug portion joins with the base portion to close an aperture at the top center. The liquid dispersal portion joins with the base portion to disperse liquid and nutrient to plants. The support portion joins with the base portion to support plants, the support portion inserts at least partially into growth medium, earth and/or soil, the support portion one piece comprising a top section and a bottom section. The top section a planar disk, curved dish or open bowl shape, the bottom section tubular, the top section above the bottom section, the top section to create a heat sink to the benefit of at least one plant.
Patent CA-2916533-A1 (CA)
Inventor: RAO SUDHA
IPC: A61K31/166
Filed: 2014-06-17
Abstract: La présente invention concerne des compositions et des procédés qui utilisent des inhibiteurs de la lysine déméthylase pour l'inhibition de la croissance des cellules souches cancéreuses ou des cellules initiatrices de tumeurs, pour améliorer les effets biologiques des médicaments chimiothérapeutiques ou de l'irradiation des cellules cancéreuses et/ou pour la prévention de la récidive du cancer.
Patent CA-2917448-A1 (CA)
Title: Merchandising display device and method
Inventor: COLLIER PAUL
IPC: A47F5/00
Filed: 2014-06-03
Abstract: The device (10) is in the form of a planar sheet (12) of material divided by means of vertical crease lines (16) into panel portions (22). The sheet is foldable about the crease lines to configure the panels to form a self supporting display stand (Figure 3). At least some of the panel portions have package supporting formations (28) for mounting packages (14) to the panel portions for display. For display purposes, the device can be hung in its planar configuration or folded to form a display stand. The device (10) can also be folded inside out into a transport configuration in which product containing packages mounted to the sheet are located internally (Figure 4).
Patent CA-2918678-A1 (CA)
Title: Grinding apparatus with load control
Inventor: SJOLANDER BO THOMAS
IPC: B24B19/00
Filed: 2014-08-12
Abstract: The present disclosure relates to grinding apparatus for grinding the hard metal inserts of rock drill bits, said grinding apparatus having said grinding machine equipped with a grinding cup driven by a motor to rotate about its longitudinal axis wherein the support system comprises an arm or lever system to control vertical movement of the grinding machine and means to provide grinding pressure, wherein the means to provide grinding pressure may be a linear actuator and load cell assembly pivotally connected to the arm or lever system.
Patent CA-2918979-A1 (CA)
Inventor: BABICH PAUL
IPC: B25H7/00
Filed: 2016-01-25
Abstract: A device is provided for use with a reference tool during the construction of metal structures. The device comprises a body having a groove formed therein for receiving a portion of a straight side of the reference tool. The body further comprises a base surface for co-operating with the surface of a metal workpiece. The base surface is configured whereby, when a portion of the straight side is received within the groove, the base surface is parallel to the straight side of the reference tool. A retention assembly is mounted on the body for retaining the portion of the straight side of the reference tool, when provided, within the groove. At least one magnet is mounted on the base surface for temporarily holding the device to the metal workpiece, thereby holding the reference tool in position.
Patent CA-2919092-A1 (CA)
Inventor: MILDE PAUL G
IPC: A47C7/00
Filed: 2016-01-27
Abstract: The present invention relates to an Adirondack style chair with an improved design that increases stability on uneven ground and increases structural strength by means of a triangular seat support assembly.  Specifically, the Adirondack style chairs of the present invention comprise first and second seat members angled toward each other to form a "V" shape where the point of the "V" extends beyond the rear of the chair so as to come together at the point of contact with the ground, a seat section attached to the top of the seat support members, a back support section attached to the seat support members to form an angle generally comfortable for sitting and two vertical first and second front legs attached to each side of the seat support member at the front or side of the chair. The present invention also relates to an Adirondack style loveseat formed by positioning two 3-point Adirondack Chairs next to each other where each chair has been fabricated to remove the abutting armrests, and the abutting front leg member does not extend above the height of the seat section.
Patent CA-2919357-A1 (CA)
Title: Light emitting diode (led) display screen
Inventor: LU CHANGJUN
IPC: H01L33/00
Filed: 2014-07-14
Abstract: An LED display screen comprises an LED display screen substrate (200), an LED chip (210), and a first jointing part (222) and a second jointing part (224). The LED display screen substrate (200) is provided with a drive circuit, and an output end of the drive circuit comprises a first positive electrode (202) and a first negative electrode (204), the first positive electrode (202) and the first negative electrode (204) being located on a first surface of the LED display screen substrate (200); the LED chip (210) is located on the first surface, and an input end of the LED chip (210) comprises a second positive electrode (212) and a second negative electrode (214), the second positive electrode (212) and the second negative electrode (214) being located on a second surface of the LED chip (210), and the second surface is opposite to the first surface; the first positive electrode (202) is jointed to and electrically connected to the second positive electrode (212) by the first jointing part (222), and the first negative electrode (204) is jointed to and electrically connected to the second negative electrode (214) by the second jointing part (224). The LED display screen solves the technical problem in the prior art that the minimum dot pitch of the LED display screen is excessively large due to limited support size during conventional lamp bead encapsulation.
Patent CA-2922557-A1 (CA)
Title: Engineered primate cystine/cysteine degrading enzymes as antineogenic agents
Inventor: GEORGIOU GEORGE
IPC: C12N9/88
Filed: 2014-08-29
Abstract: Methods and compositions related to the engineering of a protein with L-cyst(e)ine degrading enzyme activity are described. For example, in certain aspects there may be disclosed a modified cystathionine-y-lyase comprising one or more amino acid substitutions and capable of degrading L-cyst(e)ine. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer with L-cyst(e)ine using the disclosed proteins or nucleic acids.