baber/WOPTO huggingface dataset:
Patent CA-2382322-A1 (CA)
Inventor: HOENKE CHRISTOPH
IPC: A61P17/00
Filed: 2000-08-17
Abstract: The invention relates to aminocarbonyl-substituted benzimidazole derivatives of general formula (I) see above formula wherein the groups R1, R2, R3 and R4 may have the meanings given in the claims and in the specification, the prodrugs thereof, processes for preparing them and the use of benzimidazole derivatives as pharmaceutical compositions, particularly as pharmaceutical compositions with a tryptase-inhibiting activity.
Patent CA-2383245-A1 (CA)
Title: Method and apparatus of electrical resistivity measurements in geological formations employing modeling data
Inventor: NICHOLS EDWARD
IPC: G01V3/28
Filed: 2000-06-28
Abstract: A method, and a system, using computer software to measure characteristics of a geologic formation (22) using vertical side scan resistivity measurements (Rm) to model characteristics such as hydrocarbon reservoirs. The method employs modeling data (23) to remove unwanted information from a signal carrying infromation from a signal carrying information concerning the geologic information (11) and models the resistivity of geologic formations.  The spatial distribution and orientation to the magnetic fields are the same, differing only by a constant related to the casing attenuation factor (24). The magnetic field outside of the cased borehole is reduced in amplitude by an attenuation factor associated with the liner. The magnetic field produced at a point outside of the liner is a function of the product of term for the attenuation factor of the liner, ke and a term for the response of the geologic formation, f. Both terms are independent of the other. by factoring (28) and removing information concerning the 20th attenuation factor, ke, accurate measurements of the geologic formation may be determined.
Patent CA-2383974-A1 (CA)
Title: Methods of treating and preventing congestive heart failure with hydralazine compounds and isosorbide dinitrate or isosorbide mononitrate
Inventor: COHN JAY N
IPC: A61K31/502
Filed: 2000-09-08
Abstract: The present invention provides methods of treating and preventing mortality associated with heart failure in an African American patient with hypertensi on and improving oxygen consumption, quality of life and exercise tolerance by administering a therapeutically effective amount of at least one hydralazine  compounds and at least one of isosorbide dinitrate and isosorbide mononitrat e, and, optionally, one or more compounds, such as, for example, a digitalis, a  diuretic compound, or a compound used to treat cardiovascular diseases. In t he present invention, the hydralazine compound is preferably hydralazine or a pharmaceutically acceptable salt thereof. Preferred methods of the invention  comprise administering hydralazine or a pharmaceutically acceptable salt thereof and isosorbide dinitrate.
Patent CA-2384582-A1 (CA)
Inventor: LASKARIS EVANGELOS TRIFON
IPC: H02K55/04
Filed: 2002-05-02
Abstract: A rotor is disclosed for a synchronous machine comprising: a rotor core; a super-conducting coil winding extending around at least a portion of the rotor, said coil winding having a side section adjacent a side of the rotor core; at least one tension rod extending through a conduit in said rotor core; and a housing attached to the tension rod and connected to the side section of the coil winding, wherein the housing comprises a pair of side panels.
Patent CA-2387541-A1 (CA)
Inventor: FRIDKIN MATITYAHU
IPC: G01N33/50
Filed: 2000-10-13
Abstract: Short segments of DAP-kinase are provided which protect cells from apoptosis - inducing signals by neutralizing the function of the endogenous DAP-kinase.< /SDOAB>
Patent CA-2389483-A1 (CA)
Inventor: WHITE MICHAEL WALTER
IPC: F16D1/076
Filed: 2002-06-06
Abstract: A dual shaft and rotating machine coupling has a rotor coupling sandwiched between aligned first and second shafts. The first shaft has a first shaft connecting flange radially extending therefrom. The first flange has opposing first axially inner and axially outer surface portions. The rotor coupling has a rotor spider and a rotor connecting flange radially extending from the rotor spider. The rotor flange has opposing first and second surface portions. Coupling studs extend from the first shaft connecting flange through the rotor flange. Each coupling stud has a coupling nut mounted thereon against the second surface portion of the rotor flange to couple the rotor flange to the first shaft connecting flange. The second rotatable shaft has a second shaft connecting flange radially extending therefrom. The second flange has a second axially outer surface portion and a pair of co-planar axially inner surface portions radially spaced from each other by a groove providing a recessed axially inner surface portion spaced from the co-planar surface portions by a predetermined distance. The pair of co-planar axially inner surface portions abut the second surface portion of the rotor flange with the coupling studs passing through the second shaft connecting flange and with the recessed axially inner surface portion being spaced to clear the coupling nuts. Additional coupling nuts are each fastened to the coupling studs and against the second axially outer surface portion of the second shaft connecting flange to couple the second shaft connecting flange to the rotor connecting flange.
Patent CA-2392138-A1 (CA)
Inventor: BERTHELET BENOIT JEAN HENRI
IPC: B24B39/00
Filed: 2001-09-20
Abstract: A method, and machine for implementing the method, for transverse ultrasound peening of blades on a rotor that drives in rotation a wheel bearing the blades about its geometrical axis arranged substantially vertically and causes the blades to pass through a mist of microbeads produced by a vibrating surface in an active chamber arranged laterally relative to the wheel. The active surface is located beneath the path of the blades. Preferably, the active chamber includes a second vibrating surface above the path of the blades.
Patent CA-2394403-A1 (CA)
Inventor: HO KAI KWONG
IPC: H05K1/14
Filed: 2002-07-22
Abstract: The invention provides a system and method for assembling an electrical module. The module comprises a circuit board, a substrate and an electrical component carried on the substrate. The substrate is formed by a stamping process an is mounted at a location on the circuit board. The substrate forms part of an electrical circuit with a circuit in the circuit board and dissipates heat from the circuit board. The substrate and the circuit board are both initially carried in respective frames. Alignment registered in the frames allow the frames to be aligned such that the substrate is positioned at the location on the circuit board.
Patent CA-2397598-A1 (CA)
Inventor: YU BAOFA
IPC: A61K31/4164
Filed: 2001-01-18
Abstract: L'invention concerne des méthodes permettant de traiter des néoplasmes, des tumeurs et des cancers, au moyen d'un ou de plusieurs haptènes et agents ou traitements coagulants, seuls ou combinés à d'autres agents ou traitements antinéoplasiques. L'invention concerne également des combinaisons et des trousses contenant les combinaisons permettant d'effectuer la thérapie.
Patent CA-2398893-A1 (CA)
Title: Improvements in and relating to controlling drug delivery apparatus
Inventor: DYCHE ANTHONY
IPC: A61J1/06
Filed: 2001-02-12
Abstract: A drug package comprising a plurality of drug vials containing drugs for delivery to a patient in a drug delivery device; and a data carrier including drug treatment information for use by the drug delivery apparatus.
Patent CA-2401760-A1 (CA)
Title: Auto activated self-defence alarm device
Inventor: CLARKE JOHN
IPC: A01M29/16
Filed: 2002-09-16
Abstract: The present invention relates to an auto activated self-defence personal alarm apparatus and system to deter or stop various types of aggressors, particularly bears or other dangerous animals. The apparatus is capable of being activated by the user/victim or, if the victim is unable to activate the apparatus in time, the alarm apparatus may be activated by the actions of an attacker upon initiating the attack, The apparatus is compact, inexpensive, simple to use, and has a loud and long lasting sound that can stun or deter even large animals, such as bears.  Optionally, it is capable of discharging smoke as an added means of frightening an attacker such as a bear. The primary and radically different feature of this device from those currently patented and/or on the market is that no action is demanded of the person carrying it in the event of an attack.
Patent CA-2402320-A1 (CA)
Title: Patient stratification for cancer therapy based on genomic dna microarray analysis
Inventor: SEELIG STEVEN A
IPC: C12Q1/68
Filed: 2001-03-29
Abstract: The method of the invention comprises the stratification of a cancer patient population into various cancer therapy groups based on analysis by genomic DNA  microarray of multiple gene amplifications or deletions present or absent in the diseased tissue of each patient. In particular, the invention involves patient stratification into one of at least four cancer therapy groups based on the microarray analysis of gene amplification or gene deletion at multiple chromosome locations. The invention has the significant clinical advantage of guiding selection of expensive cancer adjuvant drugs for use with patients most likely to respond positively to the individual drug. For example, a genomic DNA microarray simultaneously measuring 59 separate gene amplifications or gene deletions in diseased tissue can be used to stratify solid tumor cancer patients, such as breast cancer patients, into at least nine groups: those most likely to respond to (i) anti-HER-2/neu therapy (Herceptin®), (ii) anti-EGFR therapy (C225 antibody), (iii) anti-AKT1 therapy (cis-platin), (iv) anti-PIK3CA therapy, (v) anti-thymidylates synthase therapy (5-fluorouracil), (iv) anti-Topoisomerase II therapy (doxorubicin), (vii) anti-cmyc therapy, (viii) combination of anti-HER-2 therapy and anti-AKT1 therapy, and (ix) combination of anti-EGFR and anti-AKT1 therapy. The invention has the further advantage of identifying patients most likely to respond synergistically to a particular combination of adjuvant therapies.
Patent CA-2405698-A1 (CA)
Title: Method for the distribution of items
Inventor: ROSENBAUM WALTER
IPC: G06Q10/00
Filed: 2001-04-09
Abstract: The present invention comprises a method for handling return requested items. The items are returned from a customer to a provider or seller. The items may be returned due to customer dissatisfaction and/or customer failure to properly compensate provider. To effect return, the provider contacts a postal system which arranges for pick up of the item, evaluates the condition and value of the item, advises the provider of the condition and value, and based on instruction from the provider, either provides item information to an auction house for auctioning (along with subsequent shipment to the auction house highest bidder) or return of item to manufacturer.
Patent CA-2406222-A1 (CA)
Title: System and method for projecting market penetration
Inventor: VON GONTEN MICHAEL
IPC: G06Q30/02
Filed: 2001-04-17
Abstract: A system for facilitating simulations and modeling of market sales volume is provided including a server including a database having a number of client files, wherein each client file is an organized client data file including a number of linked web pages which are downloadable and displayable to a client program at a remote client having a graphical user interface. The system further includes an input device coupled to the remote client and on-line to the server. The system includes at least one web page including a data field for entering a parameter for an analysis of a client file and software means operable on the server and the client program at the remote client for projecting penetration of merchandise at a predetermined number of weeks, W, since a Launch of a product, based on weekly data of initial purchases from a launch of a product. The software means is operable on the server and the client program at the remote client for generating a curve from weekly sales data wherein the curve plots a set of weekly sales data versus number of weeks from the launch of the product. The software means is operable on the server and the client program at the remote client for retrieving a component of the curve (B) representing a degree of belly of the curve, retrieving a component from the curve representing a slope; term (S) and performing a calculation to produce a predicted or continued value for components of market sales volume using the B component and the slope component (S) in a formula, wherein the formula is:     Predicted = Exp (S)x W B
Patent CA-2407147-A1 (CA)
Title: Boite composable de haute stabilite
Inventor: RUSSO GERLANDO
IPC: B65D1/22
Filed: 2000-07-21
Abstract: La présente invention concerne une boîte composable faite d'un élément formé en plastique. Cet élément comprend un panneau central (12) rectangulaire s'articulant sur les bords, via des lignes de pliage (17, 18), avec quatre côtés de panneaux latéraux (13, 14, 15, 16) se repliant sur le panneau central (12) en forme de boîte. Des éléments de coins assurent un formage et un blocage (25) entre le panneau central et les panneaux latéraux. Les panneaux latéraux sont équipés de bords rabattants (20, 21) qui dépassent sur l'extérieur des panneaux latéraux (13, 14, 15, 16) et qui peuvent se placer les uns le long des autres dans une position en forme de boîte fermée par insertion deux par deux dans une fente (37) de chaque élément de coin, à des fins de formage et de blocage (25). En l'occurrence, les bords rabattants (20, 21) constituent des éléments longitudinaux et transversaux d'engagement et de liaison (23, 27; 29, 30; 31, 32) conçus pour créer un positionnement mutuel stable entre les bords rabattants (20, 21).
Patent CA-2408938-A1 (CA)
Inventor: WINTERTON LYNN COOK
IPC: G02B/
Filed: 2001-05-28
Abstract: The invention relates to novel composite materials comprising (a) an inorganic or organic bulk material having attached to its surface at least one polyionic material that comprises covalently bound initiator moieties for radical polymerization; and (b) a hydrophilic surface coating obtainable by applying one or more different ethylenically unsaturated hydrophilic monomers or macromonomers to the bulk material surface provided with the initiator radicals and polymerizing said monomers or macromonomers. The composite materials of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus useful for the manufacture of biomedical articles such as ophthalmic devices.
Patent CA-2409037-A1 (CA)
Inventor: SMITH NEALE BREMNER
IPC: G06F9/44
Filed: 2001-05-18
Abstract: The present invention relates to a system (10) and method of throttling parallelism in a parallel processing system, where the throttle performs the decision with a hardware decision making means (12) and the suspension of thread execution is performed in software (11) and the data related to suspended threads are stored (13) until they are reactivated.
Patent CA-2411351-A1 (CA)
Inventor: STERK GEERT
IPC: A61K31/50
Filed: 2001-06-01
Abstract: Les composés de la formule I, dans laquelle Ar¿1?, A, R6, R7, R8 et Ar¿2? ont le sens donné dans le descriptif, sont des agents thérapeutiques bronchiques¿ ?efficaces.
Patent CA-2413279-A1 (CA)
Title: Apparatus and method for mounting a detector
Inventor: OSMANI LULZIM
IPC: G01D11/30
Filed: 2002-12-02
Abstract: A stand alone detector has two housings which are joined by a multi-conductor. aesthetically acceptable electrical cable. One housing can be plugged, via prongs into an available AC receptacle. The other housing can be located at an appropriate location for sensing the respective condition such as heat, gas, smoke, intrusion or position. The housings are releasably coupled to the cable.
Patent CA-2413796-A1 (CA)
Inventor: JONES STUART A
IPC: B29B17/04
Filed: 2001-06-22
Abstract: L'invention concerne un procédé continu de fabrication de tapis (10) ou d'un autre revêtement de sol permettant d'utiliser une variété de matériaux, notamment du PVC recyclé provenant de tapis usés et de déchets de fabrication de tapis. Le procédé continu permet de former un endos (12) et de fournir cet endos à un étage de stratification afin de le relier à un tissu d'endroit (14). Ce procédé continu permet de réduire la durée de fabrication et les coûts associés du fait que couche d'endos, lors de sa fabrication, est immédiatement stratifiée avec le tissu d'endroit. De plus, la formation de la couche d'endos à l'aide d'un procédé séparé du procédé de stratification permet de protéger le tissu d'endroit contre une chaleur et une pression excessives, et d'améliorer les nombreux types de matériau, notamment les matériaux de recyclage ou de déchet provenant en particulier de tapis usés et de sous-produits de tapis usés. L'utilisation de ces matériaux bon marché réduit à la fois les coûts de fabrication d'un revêtement de sol, la quantité de déchets de décharge et les préoccupations environnementales associées.
Patent CA-2417395-A1 (CA)
Inventor: GEORGESCU BOGDAN ALEXANDRU
IPC: H03H7/09
Filed: 2003-01-27
Abstract: A monolithic transformer compensated circuit with enhanced quality factor without significantly increasing noise levels is presented in this disclosure. The technique uses a monolithic transformer and a current source driving current into the transformer secondary winding to achieve loss compensation in the transformer primary. An ac current which is proportional to, and in phase with the voltage applied to the primary winding can be used to achieve theoretically perfect loss compensation at a given Frequency in the RF (GHz) frequency range. Examples of circuit applications that are particularly suited to the technique include Voltage Controlled Oscillators (VCO's), Low Noise Amplifiers (LNA's) and Filters. The technique has the added advantage of reducing power consumption in some applications.
Patent CA-2418012-A1 (CA)
Title: Method and composition for cleaning and maintaining water delivery systems
Inventor: AGER SCOTT P
IPC: C02F5/10
Filed: 2001-08-03
Abstract: A sodium chlorite solution (26) is admixed with a second solution containing an acid (28) to make a reacted mixture (30). The reacted mixture is introduced into a water system, viz. a conduit (12) in which water flows or a tank containing water. The reacted mixture is added to the water system to inhibit and/or eliminate bacterial fouling in the system, and/or inhibiting and/or removing mineral deposits from the system, and/or for reducing or eliminating microorganisms from the system. The second component is acidic enough to convert the sodium chlorite into chlorine dioxide while remaining unaffected in the reacted mixture and at the same time being a mineral antiscalant.  Optimum conversion of the sodium chlorite component into active chlorine dioxide requires at least several minutes reaction time and, preferably, the use of a suitable catalyst, such as sodium molybdate.
Patent CA-2420343-A1 (CA)
Inventor: CORMIER MICHEL J N
IPC: A61B10/00
Filed: 2001-08-20
Abstract: A minimally invasive transdermal nucleic acid sampling method comprises piercing through the outermost layer of the skin (20) and into the underlying epidermis with a plurality of microprojections (4). Living skin cells in the underlying epidermis are disrupted, causing them to release their contents including their nucleic acids (i.e., DNA, RNA, fragments thereof or other polynucleic acid material found in teh cleic and/or mitochondria of cells).  The nucleic acid is collected on the surfaces of the microprojections and/or in a separate nucleic acid collection reservoir. The collected nucleic acid is then analyzed using standard polymerase chain reaction (PCR) techniques.  Optionally a suction device (10) applies a partial vacuum through openings (8) in the microprojetion member (6) to the microcuts in the skin (20) for enhance defflux of intraelular and extracellular (i.e., body) fluids containing the nucleic acid.
Patent CA-2421229-A1 (CA)
Inventor: COLACO CAMILO ANTHONY LEO SELW
IPC: A61P37/04
Filed: 2001-09-04
Abstract: The present invention provides a vaccine comprising a microbial pathogen, wherein the microbial pathogen is subjected to a stress inducing stimuli. The stress inducing stimuli can be heat or osmotic stress, through preferably the microbial pathogen is genetically modified such that at least one repressor gene for a heat shock protein gene is inactived, this allowing the constitutive expression of heat shock proteins. In particular the use of heat shock protein repressor mutant bacteria is shown to be effective for inducing immunity when comprised within vaccines of the present invention. The present invention further provides a method for producing a vaccine comprising stressed induced microbial pathogens and further the use of the heat shock protein repressor deletion mutant microbes as vaccine vectors which can be additionally allow the expression of heterologous antigen fragments.
Patent CA-2421261-A1 (CA)
Title: Pellet press for dry ice
Inventor: JOHANSEN STEEN
IPC: C01B32/55
Filed: 2001-08-14
Abstract: In an apparatus for making dry ice pellets having plural pressing chambers, each pressing chamber is provided with a movable piston for compressing carbon dioxide into solid state and for pressing the solid carbon dioxide through a perforated plate disposed at the end of the pressing chamber. Through connecting rods, the pistons in the pressing chambers are connected with a common crankshaft driven by a motor. The pressing chambers are provided with an inlet for supplying the carbon dioxide in fluid state and with outlet for carbon dioxide in gaseous state. In this way a very compact construction is achieved which is suited for mobile units, particularly dry ice blasting units.
Patent CA-2422928-A1 (CA)
Inventor: GRIFFIN MICHAEL
IPC: A61L11/00
Filed: 2001-09-21
Abstract: There is provided an apparatus (2) for the reduction of organic waste (4) in which the apparatus (2) comprises a conveyor (32, 40, 128) to move the waste (4) within the apparatus (2). There is also provided a first chamber (10) comprising weighing means to determine a weight of the waste and purging means to purge the apparatus of oxygen. A second chamber (12) comprises reduction means to treat, sterilize and reduce the waste for a first period of time and a third chamber comprises cooling means to cool the reduced and sterilized waste for a second period of time. There is also provided sealing means (18, 34, 36) to seal each of the first (10), second (12) and third (14) chambers from the other chambers and from exterior of the apparatus when in use.
Patent CA-2424118-A1 (CA)
Title: Systeme respiratoire
Inventor: MEAKIN GEORGE HAROLD
IPC: A61M16/08
Filed: 2001-09-21
Abstract: L'invention concerne un système respiratoire comportant un sac réservoir interne flexible pourvu d'un orifice d'entrée de gaz exhalé et un orifice de sortie de gaz, et un second sac externe flexible dans lequel le sac interne est disposé, l'orifice de sortie de gaz du sac interne débouchant dans le sac externe, et le sac externe étant pourvu d'un orifice de sortie de gaz exhalé qui, lors de l'utilisation, est relié à un tube de réception de gaz. Un premier conduit relié à l'orifice d'entrée du sac réservoir interne communique avec un masque facial appliqué sur le nez et la bouche d'un patient. Un deuxième conduit relié à l'orifice de sortie du sac externe non rigide communique avec un orifice d'évacuation de gaz. Un troisième conduit relié à une alimentation en gaz frais communique avec le masque facial. Le premier conduit peut être inclus dans une première partie du deuxième conduit, et le troisième conduit peut être inclus dans une deuxième partie du deuxième conduit, formant ainsi deux tubes coaxiaux. Le premier et le troisième conduit peuvent se rejoindre sur une pièce en T à laquelle le masque facial est relié.