Patent SG-11201808804T-A (SG)
Title: A method to enhance wound healing using silk-derived protein
Inventor: ABDEL-NABY WALEED
IPC: C07K14/78
Filed: 2017-04-07
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 1#11101111011101010111110101111 1 001010111011011011011101111011110111111 Organization International Bureau (10) International Publication Number (43) International Publication Date .....0\"\" WO 2017/200659 A2 23 November 2017 (23.11.2017) WIPO I PCT (51) (21) (22) (25) Filing Language: (26) (30) (71) (72) International Patent Classification: Not classified International Application Number: PCT/US2017/026656 International Filing Date: 07 April 2017 (07.04.2017) English Publication Language: English Priority Data: 62/320,177 08 April 2016 (08.04.2016) US Applicants: CORNELL UNIVERSITY [US/US]; Cen- ter for Technology Licensing (CTL), 395 Pine Tree Road, Suite 310, Ithaca, New York 14850 (US). SILK TECH- NOLOGIES, LTD. [US/US]; 3700 Annapolis Lane North, Suite 105, Plymouth, Minnesota 55447 (US). Inventors: ABDEL-NABY, Waleed; 208 Bay 22nd Street, Apt. C2, Brooklyn, New York 11214 (US). ROSEN- BLATT, Mark; c/o Cornell University, CTL, 395 Pine Tree Road, Suite 310, Ithaca, New York 14850 (US). LAWRENCE, Brian; 3700 Annapolis Lane North, Suite 105, Plymouth, Minnesota 55447 (US). INFANGER, David; 3700 Annapolis Lane North, Suite 105, Plymouth, Minnesota 55411 (US). (74) Agent: EWING, James F. et al.; Foley & Lardner LLP, 3000 K. Street N.W., Suite 600, Washington, District of Co- lumbia 20007 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, _ = = = (54) Title: A : burns, and skin ulcers, weight 0 incisions, METHOD TO ENHANCE WOUND HEALING USING SILK-DERIVED PROTEIN Also described are compositions SDP S ution Prtaductiof , Pro e s = = = = = = tract fitroil Pan COMMIS Dtasolve Main in IRS-solution Antockeve Min/RA/Br solution Av Fibroin Solution Ditlyth Li& Seft NMI solution Ftff-4183i mg/Iota:1 anis coma m Ilatats SOP aft ic product = = — = Pri Silk Production. !Aiwa Liar NW 'nom solution Process Mr-out ;9regAto aa 3taTrinilte8 = = — = Martin rare cocoons Dissolve Malin wail Ilk solution Prior at Wk Rama * Vlitliert . product = Fig. 1 enhancing wound healing using silk -derived proteins (SDP), including low molecular for the treatment fragments, including low molecular wight SDP fragments. ei c:r irl ,tD 0 0 ei .---- (57) IN ei SDP fragments. Described herein are methods of comprising SDP of wounds, including corneal wounds, skin wounds, surgical o [Continued on next page] WO 2017/200659 A2 MIDEDIM01101 DIVIIMMEM00101011101111111111111011111011110111111 TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — without international search report and to upon receipt of that report (Rule 48.2(g)) be republished