baber/WOPTO huggingface dataset:
Patent CA-2144773-A1 (CA)
Title: Brain enhanced delivery of neuroactive peptides by sequential metabolism
Inventor: BODOR NICHOLAS S
IPC: C07K5/103
Filed: 1993-09-17
Abstract: The invention provides novel peptide derivatives which are designed to deliver pharmacologically active peptides into the central nervous svstem by sequential metabolism. The peptide is placed in a molecular environment which disguises its peptide nature and provides biolabile, lipophilic functions to penetrate the blood-brain barrier by passive transport. The design incorpo-rates a dihydropyridine-type redox targetor moiety, an amino acid or di- or tripeptide spacer inserted between the targetor and N-terminal amino acid unit of the peptide and a bulky, lipophilic substitutent protecting the C-terminal amino acid unit of the pep-tide. The dihydropyridine-type targetor undergoes an enzymatically mediated oxidation to a hydrophilic, membrane-imperme-able pyridinium salt. That polar targetor-peptide conjugate is trapped behind the lipoidal blood-brain barrier. Over time, cleavage of the lipophilic ester from the peptide by esterase and/or lipase enzymes and enzymatic cleavage of the targetor-spacer from the peptide results in release of the desired peptide in the brain.
Patent CA-2148026-A1 (CA)
Title: Winch Bar
Inventor: CHAN MEE PHENG
IPC: B60P7/08
Filed: 1995-04-27
Abstract: There is a winch bar for winding a winch having a winding drum with an annular wall and a circular opening. A plurality of winch bar receiving apertures extend diametrically through the drum on opposite sides of the wall. The winch bar has an outer portion dimensioned to extend through the apertures. The winch bar also has an inner portion larger than the apertures and a first shoulder between the inner portion and the outer portion. The outer portion includes an outer tip which tapers outwardly. There is a first segment of reduced section adjacent the tip and dimensioned to receive the wall of the drum on the first side thereof. A second shoulder is located between the tip and the first segment. There is a second segment of reduced section adjacent the first shoulder and which is dimensioned to receive the wall of the drum on a second side thereof. The bar has a third segment having a larger section than the first and second segments and which is located therebetween. The third segment is dimensioned to fit within the central opening of the drum between the first and second sides of the annular wall.
Patent CA-2153224-A1 (CA)
Title: Device for cutting cheese, vegetables, sausage and like products into slices
Inventor: VEDDER RONALD FERDINAND
IPC: B26D3/24
Filed: 1995-07-04
Abstract: A device for cutting cheese, vegetables, sausage and like products, into slices, comprising a supporting surface for the product to be cut and a knife, wherein adjacent an end edge of the supporting surface a stop plate for the product to be cut is arranged, extending transversely to the supporting surface, which stop plate is coupled with an upwardly and downwardly movable knife holder comprising an elongate knife, which knife holder is situated near the upper edge of the stop plate, while the distance between the stop plate and the knife in a direction transverse to the stop plate defines the thickness of the slices to be cut, and an electric motor is provided for effecting the up and down movement of the knife holder.
Patent CA-2153966-A1 (CA)
Title: Multimedia player component object system
Inventor: MILNE STEVEN H
IPC: G06F17/30
Filed: 1994-01-06
Abstract: A technique for providing routing of various multimedia events throughout the course of a multimedia presentation using a computer with a storage and a display. A processor with an attached display, storage and multimedia device builds a component object in the storage of the processor for managing the multimedia device including at least one port for exchanging multimedia information. The processor includes a connection object for connecting the at least one port to the multimedia device to facilitate the exchange of multimedia information and the processor routes information between the multimedia device and the component object port.
Patent CA-2154051-A1 (CA)
Inventor: BETREMIEUX ISABELLE
IPC: B32B27/08
Filed: 1995-07-17
Abstract: L'invention concerne un matériau comprenant: - un polymère A comprenant: 1) au moins un produit choisi parmi les polyamides, les alliages de polyamide, les copolymères ayant des blocs polyamides et des blocs polyéther, 2) au moins un produit choisi parmi le polyéthylène, les copolymères de l'éthylène, le polypropylène, les copolymères du propylène, ces produits étan t greffés par un diacide carboxylique insaturé ou son anhydride, - le polymère A adhérant essentiellement sans adhésif sur un caoutchouc EPDM ou EPM vulcanisé.
Patent CA-2156176-A1 (CA)
Title: DNA Polymerases with Enhanced Thermostability and Enhanced Length and Efficiency of Primer Extension
Inventor: BARNES WAYNE M
IPC: C12P19/34
Filed: 1994-02-22
Abstract: A DNA polymerase having an amino acid sequence comprising substantially the same amino acid sequence as that of Thermus aquaticus or Thermus flavus DNA polymerase, excluding the N-terminal 280 amino acid residues of Thermus aquaticus DNA polymerase or the N-terminal 279 amino acid residues of Thermus flavus DNA polymerase, recombinant DNA sequences encoding said DNA polymerases, vectors comprising said DNA sequences, and host cells containing such vectors. A formulation of thermostable or other DNA polymerases comprising a majority component comprised of at least one thermostable or other DNA polymerase of the type described above, wherein the DNA polymerase lacks 3'-exonuclease activity, and a minority component comprised of at least one thermostable DNA polymerase exhibiting 3'-exonuclease activity, and an improved method for enzymatic extension of DNA strands, especially while, but not limited to, amplifying nucleic acid sequence by polymerase chain reaction wherein the above formulation is made and used to catalyse primer extension, are also provided.
Patent CA-2159498-A1 (CA)
Inventor: CHA YOUNSIK
IPC: A61M11/00
Filed: 1994-03-31
Abstract: sclosed is a method of delivering a preset amount of a drug used to treat a skin disorder.\!
Patent CA-2160038-A1 (CA)
Inventor: DENNIS MICHAEL
IPC: C07K14/705
Filed: 1995-10-06
Abstract: This invention relates to the use of reagents in a novel manner to screen compounds in vitro for their ability to interact with and modulate the functional properties of receptors coupled to guanyl nucleotide-binding regulatory proteins (G-proteins).Methods are described herein for determining the ability of compounds to act as antagonists by observing their ability to downregulate recombinant G-protein coupled receptors in membrane preparations.  The methods described permit the downregulation effect to be observed within a time frame that is dramatically accelerated compared to other known methods of testing the same effect, thereby providing novel and improved efficient means of screening compounds for their probable pharmaceutical efficacy.  This invention also relates to the use of such reagents and methods in kits.
Patent CA-2160041-A1 (CA)
Title: Wound Dressing Support Device
Inventor: REICH MARSHALL P
IPC: A61F15/00
Filed: 1995-10-06
Abstract: A wound dressing support device for holding a variety of standard gauze pads in place on top of an open wound and for providing for painless access to the wound. The wound dressing support device consists of an elongated elastic unidirectional wrap which includes a window opening therethrough. The unidirectional wrap is adaptable for conforming to various parts of the anatomy of a patient and includes releasable loop and hook fasteners for securing the wrap around the trunk, head, limb, hand and other parts of the anatomy. The window opening may be of different widths, lengths and geometric shapes for application to different sizes and types of wounds. The window opening is accessed above and on top of one or more gauze pads placed on the wound bed. The wound dressing support device includes loops and hooks around the perimeter of the window opening for releasable engagement of a portion of the sides of the gauze pad. When the dressing is released, the used gauze pad can quickly be removed from the wound bed and replaced with a fresh gauze pad. The window in the wrap allows for visual inspection of the gauze pad relative to the nature of wound drainage, the amount of drainage, and when the dressing needs to be changed. The window further allows for improved evaporation of gases and liquids secreted from the wound and through the gauze pad.
Patent CA-2164917-A1 (CA)
Title: Electrically heated mudflap
Inventor: PATRAKIS STRATI
IPC: B62D25/18
Filed: 1995-12-11
Abstract: An electrically heated mudflap is disclosed for use in the fender well  structure of a vehicle which includes electrical heating elements located within the mudflap.  The electrical heating elements are operatively connected to the vehicle's electrical system.  By energizing the heating elements, accumulated snow and ice will be melted away from the fender area of the vehicle, thereby increasing vehicle handling and stability.  The heated mudflap may be fastened to the vehicle's fender well through the utilization of any known fastener devices.  The heated mudflap may be connected to the vehicle's electrical system through the utilization of any known electrical connector devices.  The heated mudflap may be retrofitted to existing vehicles or employed in new vehicle design.
Patent CA-2166928-A1 (CA)
Title: Radio communication device having a moveable housing element and a keypad disposed therein
Inventor: JAMBHEKAR SHIRIANG NILKANTH
IPC: H04W88/02
Filed: 1996-01-10
Abstract: A radio communication device (103) operable in a radio communication system (100) providing a plurality of radio communication services including radiotelephone, facsimile and electronic mail services. The radio communication device (103) has a body housing element ( 107) and moveable housing element ( 109). When the moveable housing element (109) is in the closed position, the moveable housing element ( 109) covers a portion of a touch screen display (119). A keypad (125) is integrated into the moveable housing element ( 109) and operable when the moveable housing element ( 109) is in the closed position. When a user depresses a key of the keypad ( 125) a portion of the key provides pressure against the touch screen display (119). The provided pressure activates a portion of the touch screen display (119).
Patent CA-2167667-A1 (CA)
Title: A binder mixture and its use in two-component coating compositions
Inventor: HOVESTADT WIELAND
IPC: C08G18/62
Filed: 1996-01-19
Abstract: The present invention relates to a solvent-free binder composition for preparing hard coatings which contains a) a polyisocyanate component having an NCO content of 10 to 35 wt.% and containing one or more organic polyisocyanates and b) a hydroxy-functional polyacrylate component having a hydroxyl group content of 10.1 to 20 wt.% and a viscosity at 23C of 200 to 20,000 mPa.s, wherein components a) and b) are present in an amount sufficient to provide an NCO/OH equivalent ratio of 0.5:1 to 2.0:1. The present invention also relates to the use of this binder mixture as the binder in solvent-free two-component polyurethane coating and sealing compositions.
Patent CA-2168347-A1 (CA)
Title: Segmented preformed intrastromal corneal insert
Inventor: SILVESTRINI THOMAS A
IPC: A61F9/00
Filed: 1994-07-28
Abstract: This invention is a preformed intra-stromal corneal insert (812, 814). It is made of a physiologically compatible polymer and may be used to adjust corneal curvature and thereby correct vision abnormalities. The insert of segment (812,814-) may also be used to deliver therapeutic or diagnostic agents to the interior of the cornea, or of the eye. The insert (812, 814) subtends only a portion of aring or "arc", encircling the anterior cornea outside of the cornea's field of view. The invention also includes a procedure for inserting the device into the cornea.
Patent CA-2169401-A1 (CA)
Inventor: MORINI GIAMPIERO
IPC: C08F210/18
Filed: 1996-02-13
Abstract: Solid catalyst components and catalysts therefrom, the catalysts comprising the reaction product of: i. a solid catalyst component containing an internal donor; ii. an Al-alkyl compound, and optionally iii. an external donor; the internal donor and/or the external donor being cyclopolyenic 1,3-diethers wherein the carbon atom in position 2 belongs to a particular cyclic or polycyclic structure containing two or three unsaturations.
Patent CA-2172176-A1 (CA)
Inventor: DONAIS MICHEL
IPC: F16L35/00
Filed: 1996-03-20
Abstract: A quick  connect/disconnect  coupling  comprised  of  a male coupling adapted to mate with a female coupling, the female coupling forming a passageway to receive the male coupling, and locking means for retaining the male coupling in said female coupling.  The locking means being comprised of a locking lever pivotably mounted to the female coupling and  having  a  cooperating  projection  adapted  to  extend through  the  coupling  into  the  passageway  to  engage  an annular cavity of the male coupling to maintain the male coupling into a mating relationship with the female coupling when the locking lever is in a closed position.  The male and female couplings are provided with a reinforced annular rim,  the reinforced annular rim of the male coupling extends radially of the coupling at a mid-portion thereof.  The reinforced annular rim of the female coupling extends  radially  of  said  coupling  at  the  distal  end thereof, such that when said male coupling is inserted and locked into said female coupling,  the reinforced annular rims of the male and female  couplings  lie adjacent one another.
Patent CA-2172890-A1 (CA)
Title: Switch driver circuit
Inventor: SCHNETZKA HAROLD R
IPC: H03K17/56
Filed: 1996-03-28
Abstract: A driver circuit for a semiconductor power switch. The driver circuit supplies a high voltage pulse to the gate of an IGBT. The driver circuit also monitors the voltage on the collector of the IGBT with respect to the emitter. If the voltage at the collector of the IGBT does not drop when the IGBT is turned on, the IGBT driver circuit detects a short circuit and triggers a linear integrator within the driver circuit. The linear integrator gently ramps down the voltage on the gate of the IGBT.
Patent CA-2176797-A1 (CA)
Inventor: WEISFLOG CLARENCE R
IPC: B65G69/00
Filed: 1996-05-16
Abstract: A loading dock bumper assembly includes at least one bracket for mounting the assembly on a surface of a loading dock.  At least one resilient bumper component is attached to the bracket, the bumper component formed of a block of resilient recycled plastic material is positioned to receive the impact of a motor vehicle backed into abutment with the dock.   The block is preferably formed of extruded high density polyethylene.   A side of the block adapted to receive contact with a motor vehicle may be provided with a slot along its length. The slot is adapted to have secured therein a wear bar substantially of equal length with the bumper component.  The preferred wear bar is a steel bar of rectangular cross section fitted into the slot with a surface thereof substantially flush with the surface of the resilient component.  At least one corner of the block preferably is provided with a chamfer cut at approximately 45° whereby lodging of a truck bumper on the assembly is obviated.
Patent CA-2177396-A1 (CA)
Inventor: BERNARD ANDRE
IPC: B23D63/04
Filed: 1996-05-27
Abstract: Un appareil portatif à écraser et à redresser les dents de lames de scie, qui comprend un assemblage à écraser et à redresser composé d'un boîtier monocoque ayant plusieurs étaux de serrage hydropneumatiques, fixes ou interchangeables, une enclume profilée ajustable par deux (2) vis de réglage, et un interrupteur à circuit jumelé. Les étaux de serrage sont formés de pistons placés d'un côté du boîtier et de butoirs placés de l'autre côté, et dont l'un de ces pistons et butoirs est situé près de la dent à écraser pour la maintenir sans vis de serrage et les autres le long du boîtier, de façon à exercer le serrage nécessaire à un écrasement et à un redressement optimum des dents sans faire de marques sur la lame. L'enclume profilée donne la possibilité de travailler les dents de la lame de scie, de la gauche ou de la droite vers le centre, de façon à modifier l'inclinaison des dents de la lame pour ainsi redresser leur affaissement. L'interrupteur à circuit jumelé, par une action à être exercée simultanément sur les boutons à pression intégrés aux manettes de maintien de l'appareil enclenche le processus d'opération du cycle de travail hydropneumatique du système de serrage et du système d'écrasement et de redressement, ce qui contribue éliminer les risques d'accidents causés par accrochage ou inattention.
Patent CA-2178088-A1 (CA)
Inventor: LOESEL WALTER
IPC: C07D495/04
Filed: 1994-12-14
Abstract: L'invention concerne un composé de la formule générale (I) où A représente un reste benzo, indolo ou thiéno; R?1¿ représente thiényle ou le groupe (a) où R?7¿, R?8¿ et R?9¿ peuvent indépendamment l'un de l'autre représenter méthyle, éthyle, propyle, phényle ou benzyle, et deux des substituants au plus pouvant être simultanément phényle ou benzyle; R?2¿, m, R?3¿ et R?4¿ sont définis dans la description. L'invention concerne par ailleurs des préparations pharmaceutiques contenant ces composés ainsi que leurs nouvelles applications pharmacologiques.
Patent CA-2181551-A1 (CA)
Title: Malarial aspartic protease inhibitors
Inventor: RUSSELL MARK A
IPC: C07K5/065
Filed: 1995-01-12
Abstract: 2,5-Diolpentylamine protease inhibitor compounds are effective as malarial aspartic protease inhibitors. Such compounds and compositions containing such compounds are effective for treatment or prophylaxis of malarial infections.
Patent CA-2182661-A1 (CA)
Inventor: DE MARE CARL
IPC: B21B1/22
Filed: 1995-03-29
Abstract: Method of producing metal sheets or strips by rolling a metal sheet or strip through cold rolling mills, characterized in that at least two work rolls (2) are textured according to a surface pattern consisting in a regular deterministic bidimensional pattern in the form of unit cells of spots, said spot being obtained through an electron beam irradiation (12) and in that the wavelengths in the longitudinal direction ¢.lambda.L! of the rolls and in the transverse direction ¢.lambda.L! of the rolls are less than 1.5 mm.
Patent CA-2184537-A1 (CA)
Title: Conductive, powdered fluorine-doped titanium dioxide and method of preparation
Inventor: KAUFFMAN JAMES W
IPC: C01G23/053
Filed: 1996-08-30
Abstract: A process for producing a conductive, fluorine-doped titanium dioxide product which is doped throughout, said process comprising the steps of: (a) reacting the precursors in a system to form fluorine-doped TiO2, said precursors consisting essentially of a titanium alkoxide and a fluorine source; (b) reducing the fluorine-doped titanium dioxide product at a temperature sufficient to form said conductive, fluorine-doped titanium dioxide product; and (c) recovering the reduced product.
Patent CA-2191644-A1 (CA)
Title: Template for forming a joint on a pipe
Inventor: MAROIS SARTO
IPC: F16L33/20
Filed: 1996-11-29
Abstract: The present invention relates to a template for forming a joint in a pipe. It comprises a template body having an elongated configuration, and a recess extending from one end of the body. The recess is of a substantially cylindrical configuration and adapted to accommodate the pipe of corresponding diameter. An entrance portion of the recess is, in cross-section, of enlarged diameter and has a configuration provided for forming the joint on the pipe of desirable shape. An extreme end portion of the recess has a rounded configuration provided to facilitate the forming of a tip portion of the pipe of the corresponding rounded configuration. An opposite end of the elongated body has a threaded portion formed on the opposite end, wherein the threaded portion is provided to facilitate forming of the joint. The threaded portion is formed around an outer wall of the body, and within a bore extending into the opposite end of the body. The extreme end of the recess has a semi-spherical configuration.
Patent CA-2196844-A1 (CA)
Title: Frequency Sweep Circuit
Inventor: ANZAI MAKOTO
IPC: H03L7/12
Filed: 1997-02-05
Abstract: A frequency sweep circuit including: a pull-in verification wave generator for generating a verification signal for pull-in verification; a sweep wave generator for generating a frequency sweep signal; a first adder for adding an output from the pull-in verification wave generator and an output from the sweep wave generator; a correlation determining unit for receiving a phase difference signal representing a phase difference between a received carrier wave and a recovered carrier wave, and an output from the first adder, determining presence/absence of a correlation between the phase difference signal and the output, and outputting a control signal for controlling the sweep wave generator; a second adder for adding the output from the first adder to the phase difference signal; a digital-to-analog converter for receiving an output from the second adder; a loop filter for receiving an output from the digital-to-analog converter; and a voltage-controlled oscillator for receiving an output from the loop filter and generating the recovered carrier wave.
Patent CA-2197567-A1 (CA)
Title: Silylium cationic polymerization activators for metallocene complexes
Inventor: DEVORE DAVID D
IPC: C25B3/23
Filed: 1995-07-06
Abstract: Catalyst systems useful in addition polymerisation reactions comprising a Group 4 metal complex and a silylium salt activating cocatalyst are prepared by contacting the metal complex with a silylium salt of a compatible, non-coordinating anion, optionally the silylium salt is prepared by electrochemical oxidation and splitting of the corresponding disilane compound.
Patent CA-2197607-A1 (CA)
Inventor: HILL BRUCE L
IPC: F23Q7/24
Filed: 1997-02-14
Abstract: An ignition circuit and method for a hot surface ignitor. The ignition process and apparatus enforces a short warm-up period for the hot surface ignitor where approximately half power is supplied at start-up to the ignitor until the ignitor warms to a point where its impedance is increased. By warming the ignitor gradually, the system power supply is not pulled down to a level which may cause malfunction of other electronics connected to the same supply. Further, the voltage level to the ignitor is controlled so that service life of the ignitor is extended.
Patent CA-2198737-A1 (CA)
Title: Remote self-powered structure monitor
Inventor: SCHOESS JEFFREY N
IPC: G01N29/42
Filed: 1995-08-30
Abstract: An acoustic rotor monitor that is an autonomous self-powered measurement instrument which can detect embedded and hidden fatigue cracks in remotely inaccessible devices such as helicopter rotor system components.  A predictive maintenance-related problem for rotor craft is the detection of fatigue cracks as a continuous real-time monitoring process under dynamic rotor system loading conditions. The rotor monitor focuses on the embedding an acoustic emission-based smart sensor directly into the rotor system to measure the high frequency stress waves indicating that a structure crack has propagated as a "self-powered" measurement without reducing structural integrity.
Patent CA-2198903-A1 (CA)
Title: Scanning image and thermotransfer foil for the production thereof
Inventor: SUSS JOACHIM
IPC: B42D25/373
Filed: 1995-08-30
Abstract: A dot-matrix image produced by a thermal transfer process has at least two types of dots, at least two types of dots having different optically active structures. The dots may also have different sizes. Also disclosed is a thermal transfer film for producing such a dot-matrix image.