baber/WOPTO huggingface dataset:
Patent EA-026572-B1 (EA)
Title: Preparation of high-purity gadobutrol
Inventor: PLATZEK JOHANNES
IPC: C07F5/00
Filed: 2012-04-17
Abstract: Described is a process for producing high-purity gadobutrol in a purity (according to HPLC) of more than 99.7or 99.8 or 99.9% and the use for preparing a pharmaceutical formulation for parenteral administration. The process is carried out using specifically controlled crystallization conditions. The more recent developments in the field of the gadolinium-containing MR contrast agents (EP 0448191 B1, CA Patent 1341176, EP 0643705 B1, EP 0986548 B1, EP 0596586 B1) include the MRT contrast agent gadobutrol (Gadovist1.0) which has been approved for a relatively long time in Europe and more recently also in the USA under the name Gadavist.
Patent EA-024918-B1 (EA)
Title: Solid fuel hot-water boiler
Inventor: NIKULIN VLADIMIR IVANOVICH
IPC: F28G1/06
Filed: 2013-08-06
Abstract: The invention relates to heat-power engineering, in particular to water heating devices for heating using solid fuel, mainly anthracite or stone coal. A solid fuel hot-water boiler includes a burning (furnace) chamber which housing elements are made with double walls forming a furnace, an ash pusher, and an ash box, a fuel hopper, a heat exchanger with installed inside vertical smoke tubes, in which vortex generators being coiled wire are installed. The vortex generators (coiled wire) are suspended along two coordinate axes in same number to the adjacent frames, and flames via links are hinged to two pairs of rocking levers, that are installed in pairs on two axles and by one single-side ends are connected with one frame, and by another ends are connected with another frame with the possibility of synchronous translational movement downward of one frame and upward of second frame and vice versa, wherein both axles are put to alternating movement by hinge-lever gear secured on these axles via a crank-and-rod mechanism by motor drive.
Patent EA-023420-B1 (EA)
Title: Substituted imidazopyridazines
Inventor: KLAR ULRICH
IPC: C07D487/04
Filed: 2011-09-06
Abstract: The present invention relates to substituted imidazopyridazine compounds of general formula (I)in which R, R, and A are as defined in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease as a sole agent or in combination with other active ingredients.
Patent EA-027672-B1 (EA)
Title: Semiconductive polyolefin composition which contains epoxy-groups
Inventor: FAGRELL OLA
IPC: H01B9/02
Filed: 2011-06-30
Abstract: The invention relates to a semiconductive polyolefin composition comprising an olefin polymer (A) comprising epoxy-groups and other comonomer(s) different from monomer units comprising epoxy-groups and which is a comonomer unit comprising an acrylate or acetate group; carbon black; and at least one crosslinking agent (B) which accelerates the crosslinking reaction of epoxy-groups and which is selected from: (i) Lewis acids, (ii) Bronsted acids different from carboxylic acids; or (iii) any mixtures thereof; wherein the Lewis acids are compounds of the following formula (I): ML(I), wherein M is an element of groups 4, 11, 12, 13 and 14 of the IUPAC periodic table (1989) except C, Si, Ge, Tl, Pb, Tc, Hg and Cd; each L is the same or different, is a ligand linked to M and is a group comprising from 1 to 30 carbon atoms independently selected from hydrocarbyl with no hetero atoms, unsubstituted or substituted with =O; -O-hydrocarbyl group, unsubstituted or substituted with =O; -O-(C=O)-hydrocarbyl group; -O-(P=O)-hydrocarbyl group; or two or three L are -O-hydrocarbyl- linked to each other via an X atom, which is C or N atom, and form together with M a cyclic ring system; and m is 1 to 4, and n is 1 to 4, with the proviso that m-n is 0; wherein the Bronsted acid as the crosslinking agent (B) is an aromatic organic sulphonic acid comprising the structural element Ar(SOH)(II), wherein Ar is a phenyl group, a naphthalene group or an aromatic group comprising three fused rings, which may be substituted or unsubstituted, and if substituted, then preferably with at least one linear or branched, saturated, unsaturated or partially unsaturated C-Chydrocarbyl group, and x is at least 1, or a precursor of the sulphonic acid of formula (II) including an acid anhydride thereof or a sulphonic acid of formula (II) that has been provided with a hydrolysable protective group(s). Furthermore, proposed is the use of said composition for the production of a semiconductive layer of a cable, a cable and a process for producing the same. A polymer composition of the invention can be crosslinked without using peroxide at all, and it is characterized by reduced odor intensity at the same time possessing an improved crosslinking and strippability properties.
Patent EA-030250-B1 (EA)
Title: Use of 2-[4-(3- or 2-fluorobenzyloxy)benzylamino]propanamides with high purity degree and pharmaceutical compositions thereof
Inventor: BARBANTI ELENA
IPC: C07C251/24
Filed: 2008-12-01
Abstract: Described is the use of therapeutically active 2-[4-(3- and 2-(flurobenzyloxy)benzylamino]propanamides and their salts with pharmaceutically acceptable acids with high purity degree, in particular, with a content of dibenzyl derivatives impurities lower than 0.03%, preferably lower than 0.01% by weight, for treating different disorders, under conditions that are not interfering with the cytochromes of the CYP450 system, in particular CYP3A4, CYP2D6, CYP2C19, CYP2C9 and do not exhibit HERG channel blocking properties. These highly pure therapeutically active propanamides are obtained by a process of submitting the Schiff bases intermediates 2-[4-(3- and 2-fluorobenzyloxy)benzylideneamino]propanamides to a reduction reaction with a reducing agent selected from sodium borohydride and potassium borohydride in an appropriate amount of an organic solvent selected from lower (C-C)-alkanols, allowing the formation and presence during a substantial position of the reduction reaction course of a suspension of the Schiff base into the saturated solution of the Schiff base into the same organic solvent. Also described are pharmaceutical compositions comprising said highly pure therapeutically active compounds provided for treating the mentioned above disorders.
Patent EA-031819-B1 (EA)
Title: Method for manufacturing a risperidone or paliperidone implant formulation
Inventor: GUTIERRO ADURIZ IBON
IPC: A61K47/34
Filed: 2013-05-31
Abstract: The invention relates to method for the manufacturing of an injectable intramuscular depot composition suitable for forming an in situ solid implant in a body and comprising a drug which is risperidone and/or paliperidone or any pharmaceutically acceptable salt thereof in any combination, a biocompatible copolymer based on lactic and glycolic acid having a monomer ratio of lactic to glycolic acid of from 45:55 to 55:45 and a dimethyl sulphoxide (DMSO) solvent. The method comprises the step of providing a biocompatible copolymer having an initial molecular weight of 56 kDa and then adjusting its molecular weight to 30-46 kDa and its inherent viscosity to a range of 0.25-0.31 dl/g by irradiating it with gamma or beta radiation in the dose range of 25 KGy measured at a temperature between -40 and +15°C. The obtained composition releases the drug with an immediate onset of action and continuously for at least 4 weeks and the composition has a pharmacokinetic profile in vivo that makes it suitable to be administered each 4 weeks or even longer periods.
Patent EA-027282-B1 (EA)
Title: Hydrochloride salts of an antibiotic compound
Inventor: ZHANG WEIJIANG
IPC: C07K9/00
Filed: 2014-03-06
Abstract: The invention relates to a compound of formula I wherein x is in the range of from about 1 to about 2. The invention also relates to pharmaceutical compositions containing such compounds; processes for preparing such compounds; and methods of using such compounds to, for example, treat a bacterial infection.
Patent EA-029415-B1 (EA)
Title: 2-OXO-3,4-DIHYDRO-2H-BENZO[e][1,3]OXAZIN DERIVATIVES
Inventor: KALLA RAO
IPC: C07D417/06
Filed: 2014-12-17
Abstract: The present disclosure relates to compounds that are sodium channel inhibitors and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes. In particular embodiments, the structure of the compounds is given by Formula (I)wherein n, R, R, R, R, R, R, Rand Rare as described herein, to methods for the preparation and use of the compounds and to pharmaceutical compositions containing the same.
Patent EA-031688-B1 (EA)
Title: Method and device for producing thermoplastic spacers
Inventor: MADER LEOPOLD
IPC: E06B3/673
Filed: 2015-01-26
Abstract: When producing insulating glass comprising at least two panes of glass (1) and at least one spacer of thermoplastic material arranged between said panes of glass, to seal the beginning (4) and the end (5) of the strand (2) of thermoplastic material the thermoplastic material is compressed with the aid of jaws (20, 21) placed against the side faces of the strand (2). In the region of the joint thus formed between the beginning (4) and the end (5) of the strand (2) forming the spacer, the width of the strand (2) is reduced with the aid of a compression die (22) with a convexly curved active face such that a depression is created. This depression has the effect that, after the assembly of an insulating glass blank, placing a second pane of glass onto the free edges of the strand (2) produces an opening that allows a pressure equalization during the subsequent compression of the insulating glass blank.
Patent EA-038395-B1 (EA)
Title: Helicopter with electric motor using atmospheric electricity "ruselectro17"
Inventor: BLESKIN BORIS IVANOVICH
IPC: B64D35/00
Filed: 2018-08-28
Abstract: The invention relates to electrical engineering, in particular to devices for atmospheric electricity use. A helicopter distinguished by having an electric motor, a voltage converter, an aerial device for atmospheric electricity use located in the helicopter that contains a receiving unit shaped as a helicopter fuselage with a fixed needle connected with the upper disk of the condenser; the device base features a needle connected by its tip with the lower disk of the condenser; a network having a spark detector on its upper branch is connected to the needles, the second electrode of this detector is connected with an induction coil which is connected with the lower needle, and the second self-induction coil is connected with a rectifier which is connected with a condenser of a bigger capacity attached to the battery; a dielectric chamber, in which a capacitor with upper and lower discs is placed, equipped with a spark arrester, with the upper and lower needles coated with dielectric, a remote control unit connected to a double switch on the upper and lower needle and an indicator of battery charge, connected to the battery, a metal protective casing covered with dielectric, its receiving unit being the surface of the helicopter fuselage, and the lower needle, insulated with dielectric from the fuselage, exiting through the lower surface of the helicopter fuselage into the atmosphere. The device can be used as an additional electric motor in helicopters.
Patent ES-2166699-B1 (ES)
Title: Maquina expendedora programable para su utilizacion como maquina otorgadora de objetos de regalo.
Inventor: SABAT ALEJANDRE MONTSERRAT
IPC: G07F11/54
Filed: 2000-02-28
Granted: 2003-10-16
Abstract: Máquina expendedora programable para su utilización como máquina otorgadora de objetos de regalo, que presenta la novedad de que los mecanismos de dos tipos de juego seleccionables y como mínimo un recipiente de bolas de goma están dispuestos en el interior de una sola hornacina, y consisten dichos juegos uno en una pluralidad de columnas verticales espaciales giratorias, accionadas por un motor, conteniendo bolas con artículos en su interior, y el otro es un conjunto de cabezales giratorios ensartados por un brazo de sustentación y fijados a una de las esquinas de dicha hornacina transparente, de cuales cabezales penden artículos de regalo. El funcionamiento del conjunto se realiza a través de una sola programable. La consola de la misma están dispuestos los botones de mando que permiten el movimiento automatizado y discrecional de giro y paro de uno u otro tipo diferente de juego.
Patent ES-2199046-B1 (ES)
Title: Calzon absorbente desechable con elasticidad lateral.
Inventor: CORONA CARLOS ALBERTO
IPC: A61F13/45
Filed: 2001-12-20
Granted: 2005-04-01
Abstract: Calzón absorbente desechable con elasticidad lateral. La presente invención se refiere a un artículo absorbente desechable, tal como un calzón absorbente desechable que tiene elásticos de ajuste por sus partes laterales, de modo que se logra un mejor ajuste del calzón al usuario sin deformar el artículo. Los elásticos de ajuste están colocados de forma paralela a los elásticos de cintura abarcando las cuatro zonas laterales del calzón considerando una configuración plana del mismo, es decir, antes de que se unan sus orillas laterales para formar las aberturas de piernas y cintura, y por fuera de la matriz o inserción absorbente del calzón.
Patent ES-2190379-B1 (ES)
Inventor: VILA PAHI FRANCISCO J
IPC: C07H5/06
Filed: 2001-12-21
Granted: 2004-11-16
Abstract: This invention relates to a process for the preparation of glucosamine sulfate, glucosamine hydroiodide, glucosamine pyruvate, glucosamine phosphate or their mixtures with glucosamine hydrochloride, by electrodialysis. Starting from glucosamine hydrochloride, the exchange of the Cl<SUP>-</SUP> for an anion selected from the group consisting of SO<SUB>4 </SUB><SUP>-2</SUP>, I<SUP>-</SUP>, CH<SUB>3</SUB>COCOO<SUP>-</SUP> and PO<SUB>4</SUB><SUP>-3 </SUP>takes place during the process. The electrodialyser comprises a cathode, anode, and means of separation composed of anion exchange membranes, cation exchange membranes, bipolar membranes or by other suitable means of separation. This invention also relates to a glycosamine sulphate containing chlorides obtainable by the process, and its therapeutic use.
Patent ES-2212737-B1 (ES)
Title: Ciclobenzaprina para tratar trastornos de ansiedad generalizada y composiciones de la misma.
Inventor: LEDERMAN SETH
IPC: A61K31/13
Filed: 2000-08-11
Granted: 2005-10-01
Abstract: Ciclobenzaprina para tratar trastornos de
ansiedad generalizada y composiciones de la misma. 
     La presente invención se refiere a métodos y
composiciones que comprenden una dosis muy baja de  ciclobenzaprina
o metabolito de la misma para prevenir y tratar el trastorno de
ansiedad generalizada. La presente invención se refiere, además, a
métodos y composiciones para tratar y prevenir síntomas asociados
con el trastorno de ansiedad generalizada, usando una dosis muy baja
de ciclobenzaprina.
Patent ES-2297950-B1 (ES)
Title: Procedimiento para la obtencion de una lamina para crear cuadros en tres dimensiones y lamina obtenida con dicho procedimiento.
Inventor: MARTINEZ CASTILLO EMILIO
IPC: B05D5/04
Filed: 2003-02-06
Granted: 2009-10-30
Abstract: Procedimiento para la obtención de una lámina
para crear cuadros en tres dimensiones  y lámina obtenida con dicho
procedimiento, a partir de una lámina delgada de material 
polimérico, como por ejemplo cloruro de polivinilo, polipropileno o 
polietilentereftalato, la cual es tratada mediante el depósito de
una capa de tinta  con determinados aditivos basados en compuestos
químicos, para posteriormente  realizar la impresión de un perfil
guía con un determinado motivo al cual el usuario  aplicará color, y
finalmente ser moldeada mediante un proceso de aportación de calor 
para la obtención del volumen y las dimensiones deseadas, con el
objetivo de que la  lámina sirva de soporte tridimensional para la
coloración mediante la aplicación de  distintos tipos de pinturas
por parte del usuario, las cuales se adherirán a la  lámina como
consecuencia del tratamiento efectuado sobre la misma.
Patent ES-2246121-B1 (ES)
Title: Dispositivo refrigerante y procedimiento para su fabricacion.
Inventor: VALLES PELLISA ROSENDO
IPC: F25D3/00
Filed: 2004-02-04
Granted: 2007-03-16
Abstract: Dispositivo refrigerante y procedimiento para su
fabricación. 
     Dispositivo refrigerante destinado
particularmente al enfriamiento de bebidas, que  comprende un envase
constituido por al menos dos partes huecas, cada una de las  cuales
está provista de al menos una brida de unión por la que se une con
otra u  otras para formar un envase, herméticamente cerrado, en el
que está contenido un  fluido refrigerante. El procedimiento para la
fabricación del dispositivo comprende  las etapas de llenar con
fluido refrigerante un envase temporal; introducir el envase 
temporal que contiene el fluido refrigerante en una de la partes
huecas que comprende  el dispositivo refrigerante; acoplar a la
citada parte hueca las partes huecas  restantes para formar un
envase herméticamente cerrado; y provocar la apertura o  ruptura el
envase temporal de forma que el fluido refrigerante contenido en él
se escape y ocupe parcialmente el espacio interior del envase
formado por las partes huecas.
Patent ES-2255443-B1 (ES)
Inventor: MARTINEZ DE LA OSSA FERNANDEZ
IPC: C02F1/72
Filed: 2004-12-03
Granted: 2007-07-01
Abstract: The invention relates to a system and method for the hydrothermal oxidation of water-insoluble organic residues. The plant comprises two independent liquid phase feed lines, namely an aqueous phase (1) and a non-water-soluble phase (9). The supercritical conditions in the entrance to the first reactor (10) enable a homogeneous phase to be obtained, in which there are no solubilization problems, thereby enabling the treatment of industrial residues that cannot be treated with standard systems. The inventive system comprises two reactor sections (14 and 18) such that it is possible to inject streams of hydrogen peroxide (11 and 15) in the connections between sections (13 and 17), in order to potentiate the oxidation reaction. The plant is equipped with a heat exchange system (5) in order to make use of the energy generated during the oxidation process, such that the plant operates in autothermal conditions.
Patent ES-2255851-B1 (ES)
Inventor: SANS ROVIRA RAMON
IPC: F16P3/08
Filed: 2004-12-17
Granted: 2007-03-16
Abstract: The invention relates to a locking device for the door of an apparatus comprising a rotary drum, and to a latch for one such device. The inventive device comprises a latch (1) articulated to a moving leaf (2) of the door, and a control box (4) attached to a fixed frame (5) of the door and configured to receive and immobilize the tip (1a) of the latch (1) into a passage (6) provided therein. The aforementioned tip (1a) acts primarily as a control tip. The latch (1) comprises at least one second tip (1b) acting as a coupling tip which is spaced apart from the control tip (1a) and which is configured such that it can be coupled in a retaining stop (13) that is attached to the fixed frame (5) of the door in a position spaced apart from the passage (6) in the control box (4)
Patent ES-2273566-B1 (ES)
Inventor: RECONDO GARAYALDE PEDRO MARIA
IPC: E05B27/00
Filed: 2005-03-30
Granted: 2008-03-01
Abstract: A security device for lock cylinders, which consist of a plug-rotor (1) which is rotatable in a cavity of a lock cylinder housing (2), which locks use true keys (4) in which the combination for opening is by means of peaks and valleys of different sizes, with the valleys operating in conjunction with respective pairs of pins (5, 6), which each comprise a plug-rotor pin (5) and a lock cylinder housing pin (6) which is loaded by a spring (7), and the plug-rotor (1) incorporating a keyway (8) for insertion of the true key (4), in which there is provided a usual virtual line (9) corresponding to longitudinal alignment of the tips of the plug-rotor pins (5) when no key is inserted; characterised in that at least one of the plug-rotor pins (5) is formed as a security pin (10) which includes some end means which prevents the security pin (10) from reaching the usual virtual line (9) in the state in which the true key (4) is not inserted or the lock is empty, and its advance reaches only a virtual security line (9B) which is shorter than that of the usual virtual line (9).
Patent ES-2265274-B1 (ES)
Title: Dispositivo conformador para maquinas conformadoras de cajas de carton.
Inventor: TELLO VALERO JOSE MARIA
IPC: B31B50/52
Filed: 2005-05-11
Granted: 2007-11-01
Abstract: Del tipo de los destinados a la conformación de cajas (2) provenientes de una plancha troquelada y plana, a la que convierte en una bandeja con refuerzos (7-12) en sus esquinas, incorpora en correspondencia con cada una de las guías verticales y fijas (1) para deformación de la plancha de cartón, un plegador basculante lateral (10) que actúa horizontalmente pasando por encima de los testeros (5'') incide sobre el sector terminal (12) de los refuerzos y lo abate sobre el sector inicial (7) de los mismos, mientras que un cabezal basculante (13) montado junto a cada uno de los testeros (5) y por fuera de ellos, bascula hacia el interior de la caja una vez que ésta ha sido conformada y mediante una pareja de cilindros contrapuestos (14) de que es portador, actúa con los correspondientes pisones (15) sobre los refuerzos (12-7) estabilizándolos entre sí al lateral interno de la gualdera (5'') correspondiente. Se acelera de esta manera y de forma muy considerable el proceso constructivo de la caja.
Patent ES-2247954-B1 (ES)
Title: Pasta ceramica gresificable.
Inventor: NEBOT APARICI ANTONIO
IPC: C04B35/00
Filed: 2005-08-19
Granted: 2007-05-01
Abstract: Pasta cerámica gresificada que tiene como componente principal un vidrio reciclado. El vidrio utilizado es el proveniente de la última clasificación de las plantas de tratamiento y que es destinado a vertederos controlados de residuos.
Patent ES-2321776-B1 (ES)
Title: Dispositivo y metodo para la medida de las aberraciones oculares basado en un sensor de curvatura.
Inventor: PUJOL RAMO JAUME
IPC: A61B3/10
Filed: 2006-03-17
Granted: 2010-04-07
Abstract: Dispositivo y método para la medida de las
aberraciones oculares basado  en un sensor de curvatura. 
     Sensor de curvatura aplicado al ojo para
determinar las aberraciones oculares.  El instrumento utiliza como
núcleo un sistema oftalmoscópico de doble paso  que permite
registrar sobre una cámara CCD de forma consecutiva o simultánea 
dos imágenes en planos ligeramente desplazados con respecto al plano
pupilar.  A partir de estas dos imágenes, se obtiene una imagen que
corresponde al  contraste entre ambas como la diferencia de
intensidades dividido por la  suma de intensidades punto a punto. De
esta imagen de contraste se calcula  la función aberración de
onda.
Patent ES-2311386-B1 (ES)
Title: Sistema de apertura y extraccion simultanea para cunas.
Inventor: MONGE MARTIN JULIAN
IPC: A47D7/00
Filed: 2006-11-27
Granted: 2009-12-03
Abstract: Sistema de apertura y extracción simultánea para
cunas consistente en un dispositivo para cunas que facilita su
apertura permitiendo a padres o cuidadores de un bebé acceder al
mismo sin levantarse de la cama, caracterizado porque el  movimiento
de la puerta (1) se transmite hasta el somier (3) mediante una cinta
o varilla (5) guiada por un conducto (13)  existiendo un elemento de
unión (2) de la puerta (1) con la cinta o varilla (5) tipo eje,
bisagra o similar que permite girar a  la puerta (1) 90 grados, para
que quede abatida sobre la estructura de la cuna. La puerta (1) se
desliza por guías (4)   descansando el somier sobre varias ruedas
(8) situadas dentro del cabecero (14) y del piecero (15) siendo el
somier (3)  solidario al respaldo (9) que se desplaza por guías (11)
apoyado en deslizaderas (12), estando garantizada la estabilidad  de
la estructura mediante largueros (10) que unen cabecero (14) y
piecero (15).