baber/WOPTO huggingface dataset:
Patent CR-20220190-A (CR)
Title: Pyrido[3,2-d]pyrimidine compounds as immunomodulators
Inventor: WU LIANGXING
IPC: A61P35/00
Filed: 2020-09-29
Abstract: The present disclosure is directed to compounds of Formula (I): which modulate PD-1/PD-L1 protein/protein interaction, compositions, and methods of treating various diseases, including infectious diseases and cancer.
Patent CR-20220612-A (CR)
Title: Processes of preparing a jak1 inhibitor
Inventor: ZHOU JIACHENG
IPC: C07D403/14
Filed: 2021-06-02
Abstract: The present application provides processes for preparing 4-[3- (cyanomethyl)-3-(3',5'-dimethyl-1H,1'H-4,4'-bipyrazol-1-yl)azetidin-1- y1] -2,5-difluoro-N-[(1S)-2,2,2-trifluoro-1-methylethyl]benzamide, and phosphoric acid salt thereof, which is useful as a selective (Janus kinase 1) JAK1 inhibitor, as well as salt forms and intermediates related thereto.
Patent EC-SP056216-A (EC)
Title: Tableta de liberación modificada del clorhidrato de bupropion
Inventor: OBEREGGER WERNER
IPC: A61K9/22
Filed: 2005-12-12
Abstract: Una tableta de liberación modificada de clorhidrato de bupropion, que comprende (i) un núcleo que comprende una cantidad efectiva de clorhidrato de bupropion, un aglutinante, un lubricante y (ii) un recubrimiento para controlar la liberación que rodea el núcleo y (iii) una barrera contra la humedad que rodea el recubrimiento para controlar la liberación, en done la tableta de liberación modificada es bioequivalente a las tabletas de Wellbutrin® o de Zyban®/Wellbutrin®SR.
Patent EC-SP067021-A (EC)
Title: Compuestos y composiciones como moduladores del receptor activado por proliferador de peroxisoma (ppar)
Inventor: EPPLE ROBERT
IPC: C07D417/04
Filed: 2006-11-22
Abstract: La invención proporciona compuestos, composiciones farmacéuticas que comprenden estos compuestos, y métodos para utilizar tales compuestos con el fin de tratar o prevenir enfermedades o trastornos asociados con la actividad de las familias del Receptor Activado por Proliferador de Peroxisoma (PPAR), en particular la actividad de PPAR.
Patent EC-SP951386-A (EC)
Title: Articulo absorbente que se conforma al cuerpo
Inventor: MAVINKURVE PRAMOD S
IPC: A61F13/15
Filed: 1995-02-17
Abstract: Se describe un artículo que se conforma al cuerpo, tal como una toalla sanitaria, el cual tiene zonas preferenciales de doblez y una zona estructural; las zonas de doblez causan que el artículo se doble de manera preferida en los lugares anterior y posterior a los labios mayores para de esa manera mantener una configuración relativamente plana en el área perianal; la zona estructural es resistente a aplastamiento por humedecimiento de manera que la porción central del artículo permanece en contacto con el usuario.
Patent EC-SP982694-A (EC)
Title: Elemento de seguridad para un articulo absorbente
Inventor: LARSSON BJORN
IPC: A61F13/15
Filed: 1998-10-14
Abstract: La presente invención se refiere a un artículo absorbente, tal como una toalla sanitaria, un protector de incontinencia, un pañal, un protector de asiento de cama, que consta de un cuerpo absorbente encerrado entre una capa cobertora impermeable al líquido, la misma que comprende una capa conductora que tiene una primera superficie y una segunda superficie; la primera superficie esta diseñada para funcionar como un elemento de seguridad para asegurar el articulo a una superficie textil o parecida al material textil, el elemento de seguridad se caracteriza principalmente por el hecho de que una serie de fibras individuales que están separadas entre si y que tienen dos extremos, están aseguradas en uno de sus extremos a la primera superficie de la capa conductora y además por el hecho de que la primera superficie, a fin de servir como una superficie de seguridad contra una superficie de material textil o parecido al material textil, es cubierta, por lo menos parcialmente, con un adhesivo. Adicionalmente, la invención también incluye un pañal con un elemento de seguridad de acuerdo con la invención para fijar el artículo ajustandose a la forma de la prenda interior.
Patent FI-20115366-A (FI)
Inventor: UKONJAERVI TAPIO
Filed: 2011-04-15
Abstract: A rotation unit, rock drilling unit and method for rock drilling. The rotation unit includes a main shaft that is rotated around its longitudinal axis by means of a rotating motor. The main shaft is supported on a body of the rotation device slidingly in the axial direction. This slide property is utilized when connection threads of drilling equipment and drilling components comprised by it are connected.
Patent FI-20175623-A (FI)
Title: A method and devices for adaptive measuring of electrochemiluminescence
Inventor: PAVLOV ANDREI
IPC: G01N33/543
Filed: 2017-06-29
Abstract: The present invention relates to a device that can generate highly energetic or hot electrons into solutions. The device comprises an electrical pulse generator, a reaction cavity having a solution into which hot electrons can be injected as a result of electrical pulses via anode and cathode electrodes by the electrical pulse generator, at least one sensor in the reaction cavity, and an adaptive system making decisions based on previous data obtained before the decision, predictive model, an algorithm and instant data for adjusting and controlling the electrical pulse generator to attain amplitude, duration and frequency values of the pulses which are the most favorable for producing hot electron flow into the solution in the reaction cavity. The present invention also relates to a method to provide and control a flux of highly energetic or hot electrons into solutions, and a computer program product.
Patent FR-1603822-A (FR)
Title: Steady-evaporation insecticide based onddvp
IPC: C08K5/521
Filed: 1968-11-18
Granted: 1971-06-07
Abstract: An insecticide composition for diffusion by vaporization contains DDVP or a related phosphate, together with regulators of evaporation on an inert absorbent support in a perforated envelope of a thermoplastic material. This gives a slow steady evaporation of DDVP into the atmosphere over several months. The support is cellulose or a polymer; the regulator has molecular weight 250, reduces the vapour pressure, and may be a plasticizer. The mixture contains 80% of DDVP; silicones and epoxides may also be included, and there may be a further outer supporting or decorative container.
Patent GB-1051226-A (GB)
IPC: F16J15/3284
Abstract: 1,051,226. Shaft seals. A. MORA. Feb. 25, 1965, No. 8134/65. Heading F2B. A seal for vehicle axles or reciprocating shafts comprises an annular element of foamed resin such as polyurethane resin and a flexible diaphragm 16 of laminated plastic. The seal shown is made by punching a piece of foamed resin from a sheet, making a groove 14 in the outer periphery, inserting the diaphragm 16 into the groove and then compressing the seal into the convex shape in a mould which is heated to seal the surface of the cellular structure, seal the diaphragm into the groove at 28 and form a locating lug 30 and a sealing lip 24. In a modification, the groove is made in the inner periphery and the diaphragm inserted to constitute the sealing lip 24. If desired, more than one diaphragm and sealing lip 24 may be provided. More than one seal may be employed for sealing the shaft bearing.
Patent GB-1051639-A (GB)
IPC: F26B3/00
Abstract: 1,051,639. Drying fuel before delivery. SIEMENS-SCHUCKERTWERKE A.G. Oct. 29. 1963 [March 23, 1963], No. 42567/63. Addition to 920,794. Heading F4B. In a steam generating installation, damp fuel such as brown coal is fed to the furnace 3 in two streams, one of which is dried in a steam drier 11, and fed with undried coal to a mixer 2. The drier 11, which is fed with exhaust steam from a turbine 5, is controlled in accordance with the moisture content of the raw fuel, so that the moisture content of the dried fuel is greater when the moisture content of the raw fuel is low, than when the raw fuel has a high moisture content. The proportion of fuel in each stream may also be varied, and the steam generator may drive a turbine 4.
Patent GB-1054550-A (GB)
IPC: E21D11/22
Abstract: 1,054,550. Mine roof supports. BERGBAUSTAHL G.m.b.H., [trading as BERGBAUSTAHL G.m.b.H & CO.]. March 10, 1964 [March 11, 19631, No. 10035/64. Heading E1E. In a yielding mine roof support overlapping channels 10, 11 are frictionally clamped together by hook bolts 12 engaging two flanged stirrups 13, the stirrups having respective locating lugs 14, 15 shaped to abut the adjacent end of the respective channels 10, 11. The lug 15 abutting the end of channel 11 may be rectangular, as shown, or may be curved; the lug 14, Fig. 3 (not shown) abutting the end of channel 10 is curved to clear the flange of channel 11. The lugs 14, 15 may be integral with the stirrups, or welded on, or may be held on by the hook bolts.
Patent GB-1072486-A (GB)
Abstract: 1,072,486. Electric meters. EVERETT, EDGCUMBE & CO. Ltd. July 14, 1964 [July 19, 1963], No. 28789/63. Heading G1Q. In a moving coil meter of the kind in which the coil 21 embraces a permanent magnet 20, the magnet is adjustable relative to the coil (a) by rotation in the plane of the coil's deflection, to vary the form of the scale law and (b) by movement perpendicular to this plane to vary the overall sensitivity. The magnet 20 is a cylinder magnetized along a diameter and secured to the casing 23 in which is fitted to annular magnetic yoke 22. Screws 27 hold the casing 23 to a disc 28 which has arcuate slots Fig. 1 (not shown) to allow relative rotation of disc and casing on slackening these screws. This provides for type (a) adjustment, in which the magnetic axis of the magnet 20 is displaced relative to the 'zero' orientation of the coil. Screw 26 provides for the type (b) adjustment.
Patent GB-1084096-A (GB)
IPC: C10K1/12
Abstract: 1,084,096. Working-up ammonia scrubbing liquors. CHEMIEBAU DR. A. ZIEREN G.m.b.H. Nov. 27, 1964 [Dec. 3, 1965], No. 48397/64. Heading C1A. A process for working-up scrubbing liquors from the ammonia scrubbing of gases containing sulphur dioxide and possibly also sulphur trioxide comprises the steps of (a) acidifying the scrubbing liquor with a mixture of alkali hydrogen sulphate and alkali sulphate (" alkali " means alkali metal or ammonium) such that sulphur dioxide is expelled therefrom, this expulsion being assisted.by heating if necessary; (b) concentrating the resulting solution by heating, cooling and separating the precipitated alkali sulphate; (c) heating the separated salt to 200-400‹ C. until substantially the whole of the ammonia is expelled; (d) partly converting the mixture of alkali -hydrogen sulphate and pyrosulphate thereby formed into sulphur oxides by heating or reduction so that such a quantity of sulphate is formed as is required in step (a) above and reintroducing the product containing this quantity into step (a) of a new cycle. In step (c) steam or inert gas may be passed through the heated melt. The alkali hydrogen sulphate and sulphate mixture added in step (a) preferably contains at least as much sulphate as the scrubbing liquor absorbed or as was formed therein. Reduction in step (d) may be effected with H 2 , S, carbon, soot or reducing sulphur- or carbon-containing compounds. A mixture of potassium sulphate and potassium hydrogen sulphate may be used in step (a).
Patent GB-1095374-A (GB)
IPC: A63C9/084
Abstract: 1,095,374. Apparatus for checking ski binding. G. C. LIPE. April 22, 1966, No. 17811/66. Heading A6D. Apparatus for checking the release point of a releasable ski binding includes a base portion engageable with a ski on which the binding is mounted, means for engaging a portion of a ski boot held in the binding, means including a movable actuator acting against a spring to apply a force to the boot-engaging means and an indicator coacting with the actuator whereby, when the actuator is moved against the spring until the opposing force built up in the spring reaches a magnitude equal to that needed to release the binding, the point of release is shown by the indicator. One embodiment comprises a base portion 30 having a force-applying means 31 and a portion 32 over which a ski is positioned during use. The force-applying means 31 includes a support 35 connected to base portion 30 by rivets 37. The support 35 is formed with a horizontal bore 38 in which a tubular actuator member 40 is sidably mounted. Movement of the actuator 40 is effected by a handle assembly comprising a pair of links 41 pivotally supported at 42 and connected at the upper ends by a cross piece 44. Rearwardly extending links 45 are pivotally connected to the links 41 and to the rear end of the actuator member by pin 47 and bushings 48. A cylindrical plunger 50 having a reduced diameter portion 51 is slidably mounted in the forward part of the actuator member 40. The forward end of the actuator tube has a lip 54 which provides a stop for the shoulder 52 of the plunger. The plunger 50 is urged into its outermost position relative to the actuator by a calibrated compression spring 57. The forward end of the plunger is provided with a boot engaging head 61, and in between this head and the lip 54 it is marked with force indicating graduations 62. An O- ring 64 is mounted on the portion 51 of the plunger, and the zero graduation mark is located on the plunger so that it is in line with the outside of the O-ring when the inside of the ring abuts the lip 54. In operation, when the binding is released, the ring 64 will have been pushed to one of the graduations 62 where it remains during the release action, indicating the release force. Other forms of the apparatus are described including a bench form of the apparatus, a form in which the actuator is operated by a screw knob, and a form suitable for use in checking heel bindings.
Patent GB-1225254-A (GB)
IPC: C02F1/00
Filed: 1968-03-15
Abstract: 1,225,254. Evaporators; desalination of water. Y. HENDERYCKX. 15 March, 1968 [16 March, 1967], No. 12776/68. Heading B1B Distilled water is obtained from salt water by passing it through heater 7 into a chamber 2 where it flows along one side of a diaphragm 4, which is permeable only to water-vapour, whereby water-vapour diffuses through the diaphragm and the air-gap 6, and then condenses on one side of wall 5 which is cooled on the other side by the flow of salt water introduced into chamber 3 through inlet I. Before passing from chamber 3 to chamber 2, the salt water flows through heater 7. Distilled water is removed from the system through outlet V; and brine is pumped out through outlet IV. The solution preferably flows through the apparatus in the form of a thin layer. The air-gap may be maintained at any chosen pressure. Diaphragm 4 may be made of cellulose acetate. Wall 5 may be a thin sheet of polypropylene. A plurality of distillation cells may be connected as shown in Fig. 2. The apparatus has six diaphragms 35, 36, 39, 40, 43, 44. The solution to be treated flows in parallel through compartments 21, 25, 29, 33, then passes through heater 47, and then flows in parallel through evaporation compartments 23, 27, 31. Distilled water is withdrawn by pump 48.
Patent GB-1228767-A (GB)
IPC: A47G27/04
Filed: 1967-08-14
Abstract: 1,228,767. Securing carpets to floors. CIMCO Ltd. 25 July, 1968 [14 Aug., 1967], No. 37308/67. Heading A4S. A device for securing adjacent carpet edges 18 to a floor, comprises an elongate member 10, having lips 19 overlying the edges of the carpets, and an elongate member 11, having a base 16 secured by nails 23 and/or adhesive to the floor, the members being secured together by engagement of a plug 12 in a channel 13 so that the height of the lips above the floor is variable to accommodate different thicknesses of carpet. Preferably at least one of the mating surfaces of the plug and channel has a series of ribs and grooves 14, 15. The base 16 has a sloping face 25 forming a key with the adhesive. Teeth 21 and an edge 22 bite into upper and lower surfaces of the carpet and, in a modification, the edge 22 overlaps the inner row of teeth. In further modifications the member 10 is of clear plastics with an embedded metal foil layer, or, when required to secure only one carpet, the base extends to one side only of the channel and the lip at the other side forms an edging slope.
Patent GB-1229590-A (GB)
IPC: H02M7/5383
Filed: 1968-04-24
Abstract: 1,229,590. Inverting. WESTERN ELECTRIC CO. Inc. 24 April, 1968 [25 April, 1967], No. 19283/68. Heading H2F. [Also in Division H3] In an inverter having two transistors 13, 14 and two capacitors 16, 17 forming a bridge circuit, the transistors are arranged to alternately conduct by having a primary winding 24-1 of transformer 24 coupled to the emitter collector paths of the transistors so as to feed regenerative feedback via two other windings 24-2, 24-3 to the transistors and a further winding 24-4 is connected between the junction of the transistors through a saturable core inductor 25 to the junction between the capacitors so as to feed a further feedback signal to the transistors to make the output waveform symmetrical by correcting for any voltage imbalance between the junction of the transistors and the junction of the capacitors. If any difference occurs in the average voltage for each half wave of voltages at 30, and 31, due to unsymmetrical conduction of the transistors 13, 14, the saturable inductor 25 produces a pulse (A, Fig. 2, not shown) in the additional winding 24-4. This modifies the sinusoidal drive current provided by tuned circuit 22, 23-1 to correct for the unsymmetrical output which may be due to differences in turn on and turn off times, storage times or saturation voltages of the transistors so as to provide a square wave output. Where say the phasing imbalance between the output wave form and the sinusoidal drive signal is such that the inductor 25 saturates to produce a correction pulse (A) of small duration say 20 degrees during the conduction cycle of the sinusoidal drive signal at say 120 degrees the modified drive signal would turn off the transistor which had been conducting at 120 degrees. However due to the short duration of the correction signal, 20 degrees, the modified drive signal would end at 140 degrees and the transistor would tend to conduct again. To avoid this a resistor 26 and capacitor 27 differentiate the correction pulse produced by the saturable inductor 25 and this further extends the length of the correction signal to maintain this transistor off and so produce a symmetrical square wave output. The frequency may be varied by variable inductor 23 and may be synchronized via the transformer 23. Alternatively an output from the transformer 23 may be used to synchronize other inverters. The output from the inverter may be taken from a winding (20-2, Fig. 1, not shown), on the transformer 20 to feed a load 11 or may drive a power inverter 32, 33, 16, 17 which feeds a load 11 via a separate output transformer 34. In this arrangement the transistor pairs 13, 32 and 14, 23 conduct alternately. Any imbalance in the output of the power inverter affects the average voltage at 31 so that the inductor 25 and differentiating circuit 26, 27 compensate for this to make the output symmetrical. Specification 1,225,421 is referred to.
Patent GB-1229621-A (GB)
IPC: F04C2/18
Filed: 1968-04-11
Abstract: 1,229,621. Rotary positive-displacement pumps and motors. H. MOLLY. April 11, 1968 [April 18, 1967; Jan. 18, 1968], No.17502/68. Heading F1F. An internally-meshing gear-pump, or motor, has a non-circular cylindrical chamber 22 housing an outer gear-wheel 24 that meshes with an inner gear-wheel 26 and is supported by pressure-loaded bearing-members 60 lodged in apertures 56, 58, which are connected to working-fluid inlet and outlet ducts 52, 54, respectively. The profile of the chamber 22 has two diametrally-opposed identical semicircular portions whose radii are equal to the radius of the wheel 24 and centres of curvature are spaced apart in a vertical direction (according to Fig. 4) by a distance exceeding the manufacturing tolerance for the distance between the axes of the wheels 24, 26, whereby there is limited freedom for the wheel 24 to move vertically and be pressed by the working fluid towards the wheel 26. A member 38 fills a crescent-shaped space between the wheels. Apertures 44, 46 through which the working fluid-flows between the ducts 52, 54 and working chambers formed by the wheels and the member 38 are provided in an axially-movable cheek-plate 42 and surrounded by gaskets 48, 50 to establish pressure-loading chambers. In a modification, Fig. 10 (not shown), the members 60 are dispensed with and the peripheral wall of the chamber 22 carries a sheet-metal ring lined with bearing metal or P. T. F. E.
Patent GB-1230791-A (GB)
IPC: H01H87/00
Filed: 1968-03-15
Abstract: 1,230,791. Current limiters. GENERAL ELECTRIC CO. 15 March, 1968 [19 April, 1967], No. 12599/68. Heading H1N. A mercury or like liquid metal interrupter comprises a channel 13, Fig. 1, for the liquid metal in a stacked array of alternately insulating and conducting discs 2, 3 compressed between metallic end members 4, 5 as by bolts 6. Provision for expansion as the metal passes to the vapour state is provided by pistons 28, 29 resiliently supported by compressible members 30, 31. Counterbores 20-23 in the end member are filled with the liquid metal by initially evacuating the chambers and provide regions of unvaporized liquid metal between which an arc may strike on interruption. Each conducting disc 2 comprises a central tungsten carbide disc 41, Fig. 4, having a slot of X section for forming the channel 13 and surrounded by a steel ring 40 grooved at 45. The insulating disc assembly 3 comprises a central disc 42, Fig. 3, of high dielectric strength alumina and having a similar slot for forming the channel 13. It is surrounded by an insulating ring 43 of soapstone, rings 44, 48 of enoprene and a thicker ring 47 of fibreglass for locating engagement in grooves 45 of the adjacent steel ring 40. The assembly is compressed by bolt 6 whereby the neoprene is reduced in thickness and the lava is stated to flow radially inwards to support the alumina disc 42. The assembly is also stated to dissipate the energy of the arc by absorbing thermal radiation, and to contain a pressure of 5-10 atmospheres in the vapour state. The use of liquid metals or low melting point metals other than mercury is referred to, e.g. gallium, indium, alkali metals or an alloy or mixture of a small quantity of alkali metal such as sodium and mercury.
Patent GB-1232158-A (GB)
IPC: H01H23/06
Filed: 1969-08-14
Abstract: 1,232,158. Switch covers. CUTLERHAMMER Inc. 14 Aug., 1969 [14 Aug., 1968], No. 40674/69. Heading H1N. A toggle switch having a hollow insulating base 2 open at the top, a metal frame including a cover 4 and a bushing 6 extending from cover 4, a toggle lever 10 pivoted on pin 12 in bushing 6 includes means for sealing both toggle lever 10 to bushing 6 and cover 4 to base 2 comprising a resilient lever seal 16a surrounding toggle lever 10 and pivot pin 12 and hugging the inner wall of bushing 6, a resilient cover seal 16c forming a closed ridge compressed between cover 4 and base 2 and resilient means 16d connecting lever seal 16a and cover seal 16c. On the lower end of toggle lever 10 is an insulating contact actuator block 14, shown in dotted lines. Resilient lever seal 16a, cover seal 16c and resilient means 16d forms a one-piece member 16 composed of resilient insulating material such as silicon rubber and is moulded in place after pivot pin 12 has been inserted, a bonding agent being first applied to bond the silicon rubber to the metal frame. Member 16 covers the whole of the inside of cover 4. Cover 4 is secured to base 2 by rivets.