baber/WOPTO huggingface dataset:
Patent CA-2443629-A1 (CA)
Title: Magnetic holding device
Inventor: BESON ROBERT
IPC: B25B11/00
Filed: 2002-04-04
Abstract: A magnetic holding (1) device and method of manufacturing same are disclosed . The device has a support structure (10) made of an iron alloy and has a substantially planer bearing surface with at least one magnetic (20) or magnetisable region located therein. Insulating means (30) made of non magnetic material are interposed between said magnetic regions and said support structure to resist magnetic induction of, or leakage to, said suppo rt structure.
Patent CA-2446929-A1 (CA)
Inventor: AZRIA MOISE
IPC: A61P19/10
Filed: 2002-05-31
Abstract: Cette invention concerne une méthode d'administration orale d'une hormone parathyroïde (PTH), consistant à co-administrer par voie orale à un patient ayant besoin de PTH une quantité efficace de PTH ainsi qu'une quantité efficace d'une calcitonine. Selon cette invention, cette méthode permet l'administration orale de PTH sans l'apparition des effets secondaires de l'hypercalcémie, l'hypercalciurie et de la lithiase rénale.
Patent CA-2455856-A1 (CA)
Title: Targeted polymeric delivery systems
Inventor: GRIFFITHS GARY L
IPC: A61K47/48
Filed: 2002-07-31
Abstract: The present invention relates to a method for targeting an agent towards a target site in a tissue comprising (a) administering to a tissue a multi-specific antibody (msAb) or multi-specific antibody fragment, comprising a targeting arm that binds to an antigen on the target site, and a capture arm that binds to a polymer conjugate; and (b) administering to the tissue a polymer conjugate that binds to the capture arm, with the polymer conjugate comprising a polymer conjugated to an agent selected from the group consisting of a therapeutic agent, a peptide, an enzyme and a labeled ligand. The present invention also relates to a kit, useful for targeting a target site in a tissue or tissue sample, comprising, (a) a multi-specific antibody or antibody fragment comprising a targeting arm that binds to an antigen on said target site, and a capture arm that binds to a polymer conjugate or hapten- polymer conjugate; and (b) a polymer conjugate that binds to the capture arm, with the polymer conjugate comprising a polymer conjugated to an agent selected from the group consisting of a therapeutic agent, a peptide, an enzyme and a labeled ligand.
Patent CA-2457854-A1 (CA)
Title: Processes for the production of alpha-difluoromethyl ornithine (dfmo)
Inventor: ZHAO SHANNON X
IPC: C07C227/42
Filed: 2002-08-23
Abstract: Provided are processes and synthetic intermediates useful for the preparation of .alpha.-difluoromethylornithine (DFMO) having the formula 1.
Patent CA-2458775-A1 (CA)
Title: Method for the extrusion of a hollow profile or similar body from a bar and corresponding device
Inventor: WOEMPNER DIETER
IPC: B21C33/00
Filed: 2002-08-23
Abstract: The invention relates to a method for extruding a hollow profile or similar body, from a bar (24), introduced into a receiver drilling (22) of a housing (18) and fed into a forming cross-section of a forming tool (24) by means of a press stamp, whereby the bar material, along with the surface of the bar (24) is expanded into a chamber (78), preceding the forming tool (32), expanding transversely to the pressing direction (x) with a central inlet and the surface is split apart. A device with a receiver or housing and a moulding tool is used in the above, between which at least one discoid adapter tool (80), with an approximately central inlet (E), is arranged before the tool inlet side of the moulding tool, in the direction of pressing, with a chamber (78), widening in the pressing direction (x), within the cross-section of which, arm inserts (88) or similar elements forming flow reducers, extend across the pressing direction (x).
Patent CA-2461509-A1 (CA)
Title: Device for wrapping a bale with a wrapping sheet, baler, and sensor(s)
Inventor: VIAUD JEAN
IPC: A01F15/07
Filed: 2004-03-19
Abstract: The invention suggests a device for wrapping a bale with a wrapping sheet, which comprises one or more sensors that detect whether the bale is wrapped properly with the wrapping sheet. A baling press is equipped with such a wrapping device as well as a control or regulating unit (ECU) that receives a signal from the one or more of the sensors and acts to interrupt the wrapping of a bale in the event the signal indicates an improper wrapping process is underway.
Patent CA-2461700-A1 (CA)
Inventor: HOFFMANN DETLEF UWE
IPC: B62K27/12
Filed: 2004-03-22
Abstract: Apparatus for releasably coupling a vehicle accessory to a vehicle is disclosed. The apparatus comprises a housing, an accessory coupler for coupling a vehicle accessory to the housing, and a hitch pin. The housing comprises an upper wall, a lower wall, and opposed side walls extending between the upper and lower walls, which walls together define a sleeve having an open rearward end. The sleeve has a height between its upper and lower walls and a width between its side walls, the width being substantially greater than the height. The upper and lower walls each have an associated hole centrally positioned widthwise of the sleeve, the holes being aligned on a common axis. The housing is adapted far attachment in an operative position to an upper rearward part of the vehicle with the open end of the sleeve depending rearwardly. In cases where the vehicle is a two-wheeled motorcycle or scooter, the housing preferably is attached to the vehicle in a location above the rear wheel of the vehicle.
Patent CA-2462000-A1 (CA)
Inventor: CARVER THEODORE E JR
IPC: C07D233/54
Filed: 2002-10-07
Abstract: The present invention is directed to a compound of Formula (I); wherein A, R 1, and R2 are defined herein. The present invention is also directed to compositions comprising compounds of Formula (I), methods of using compounds of Formula (I), and methods of making compounds of Formula (I).
Patent CA-2463167-A1 (CA)
Title: Production, detection et utilisation de cellules issues d'une transformation
Inventor: MCARTHUR HAMISH ALASTAIR IRVIN
IPC: C12P17/02
Filed: 2002-10-17
Abstract: On effectue la biosynthèse d'un composé ou d'une famille de composés bioactifs par une cellule utilisant une pluralité d'activités enzymatiques. L'invention concerne des cellules hôtes manquant pratiquement de cette bioactivité mais possédant au moins une première de ces activités enzymatiques (ou un acide nucléique codant un enzyme correspondant). Ces cellules sont transformées par un acide nucléique dont l'expression permet d'obtenir au moins une deuxième activité enzymatique permettant à ces cellules de produire un composé bioactif. Une famille de cellules peut être transformée par une multiplicité de différents acides nucléiques, ce qui permet d'obtenir une banque de cellules contenant des cellules produisant différents produits bioactifs et des cellules ne produisant aucun produit bioactif. On peut cribler les cellules transformées afin de rechercher leur bioactivité. On peut isoler et cultiver des cellules actives et isoler des composés bioactifs.
Patent CA-2464527-A1 (CA)
Inventor: WALLS MICHAEL A
IPC: C07K19/00
Filed: 2002-10-28
Abstract: La présente invention concerne des compositions et des procédés de fabrication et d'utilisation de formulations thérapeutiques de polypeptides hybrides multivalents comprenant des peptides immunogéniques de protéines M en provenance de plusieurs sérotypes différents de streptocoques du groupe A, et des anticorps dirigés contre ces derniers. L'invention se rapporte également à des acides nucléiques codant ces polypeptides hybrides. Les polypeptides de l'invention peuvent être utilisés, par exemple, selon des procédés qui permettent de traiter ou prévenir une infection microbienne et de susciter une réponse immunitaire de protection par des anticorps opsoniques largement protecteurs en l'absence d'anticorps tissulaires de réaction croisée.
Patent CA-2466186-A1 (CA)
Title: Use of sulfide-containing gases and liquors for removing mercury from flue gases
Inventor: DOWNS WILLIAM
IPC: F23J15/00
Filed: 2000-03-28
Abstract: A method and apparatus for reducing and removing mercury in industrial gases, such as a flue gas, produced by the combustion of fossil fuels, such as coal, adds hydrogen sulfide and/or sulfide ions to the flue gas as it passes through a scrubber. The scrubber may be either a wet or dry scrubber for flue gas desulfurization systems.
Patent CA-2466264-A1 (CA)
Inventor: MATSUMURA HIROYOSHI
IPC: C12N9/90
Filed: 2002-09-27
Abstract: It is intended to provide a method of designing an antiallergic agent, a sleep controlling agent, an antiobestic and a remedy for brain injury acting via the inhibition of the biosynthesis of prostaglandin D2. Crystals of a complex of human-origin hematopoietic prostaglandin D synthase, glutathione and a substrate analog or an inhibitor, etc. are prepared and the three-dimensional structural coordinate of each atom in the complex is determined by X-ray crystal analysis.
Patent CA-2467589-A1 (CA)
Inventor: BEVAN CHRISTOPHER GRAHAM
IPC: D04H18/04
Filed: 2002-11-29
Abstract: Sheet material is made from a mixture of base fibres, such as leather fibres , and bi-component synthetic fibres which have outer layers which melt at a lower temperature than their inner cores. The fibres are mixed, formed into a web and then heated so that the synthetic fibres fuse together to form a network within the web. The base fibres are then tangled, whilst constrained by the network, preferably using hydroentanglement. A high quality reconstituted leather sheet material can be produced.
Patent CA-2469585-A1 (CA)
Inventor: SRINIVASAN SARANGAPANI
IPC: A61N1/30
Filed: 2002-12-11
Abstract: La présente invention concerne un dispositif permettant d'appliquer de l'oxygène de façon à favoriser la guérison des plaies et la réparation des tissus. Le dispositif comporte un dispositif portable générant de l'oxygène (18), incluant une cathode (10), une anode (16) et une membrane conduisant les ions (18) traitée à l'acide phosphorique.
Patent CA-2470065-A1 (CA)
Inventor: DESOS PATRICE
IPC: A61K31/542
Filed: 2004-06-11
Abstract: Composés de formule (I): (see formula I) dans laquelle: R1 représente un hétérocycle, R2 représente un hydrogène, halogène ou un hydroxy, A représente CR4R5 ou NR4, R3 représente un hydrogène, alkyle ou cycloalkyle, R4 représente un hydrogène ou un alkyle, ou bien A représente un azote et forme avec -CHR3- adjacent le cycle (see formula II ) dans lequel m représente 1, 2 ou 3, R5 représente un hydrogène ou halogène, leurs isomères ainsi que leurs sels d'addition. Médicaments.
Patent CA-2470108-A1 (CA)
Title: Method for determining the activity of ornithine decarboxylase and for identifying effectors of ornithine decarboxylase activity
Inventor: MANGOLD URSULA
IPC: C12Q1/527
Filed: 2002-12-10
Abstract: The present invention relates to a method for determining the activity of ornithine decarboxylase and for identifying effectors of ornithine decarboxylase activity, to the effectors of ornithine decarboxylase activity, and to the use thereof as pharmaceuticals for the treatment of disorders of the polyamine level.
Patent CA-2470533-A1 (CA)
Title: Drug nanoparticles from template emulsions
Inventor: TUCKER CHRISTOPHER J
IPC: A61K9/16
Filed: 2003-01-10
Abstract: A method for producing micron-sized or submicron-sized drugs is disclosed, which comprises preparing a template emulsion comprising water and a templating agent; preparing a drug-containing mixture comprising a drug substance; and combining the template emulsion with the drug-containing mixture to form a template emulsion loaded with drug particles. Drug particles prepared from this process are also disclosed. The resulting drug particles demonstrate faster dissolution rates and enhanced bioavailability as compared to unprocessed drug particles and particles prepared using other processes.
Patent CA-2472555-A1 (CA)
Title: Rain and waterproof suit having flotation capabilities
Inventor: ROY ROBERT
IPC: A41D13/012
Filed: 2004-06-18
Abstract: A waterproof body suit with an integrated hood, a nose and mouth shield, a torso portion defined at its bottom by a belt, legs portion terminating as integrated socks and being covered with booties having soles, a pair of standard sleeves and a second pair of sleeves terminating with integrated mittens.
Patent CA-2472610-A1 (CA)
Inventor: JOHNSTON CHRISTINE C
IPC: B29C43/00
Filed: 2003-01-13
Abstract: The present invention provides an improved method and materials for forming biodegradable containers that can hold food products in dry, damp or wet conditions and provides the biodegradable containers prepared according to the disclosed process. The containers are produced through the use of a pre-gelled starch suspendion that is unique in its ability to form hydrated gels and to maintain this gel structure in the presence of many other types of materials and at low temperatures.
Patent CA-2473854-A1 (CA)
Title: Device for characterizing the flow of a multiphase fluid in a tubing
Inventor: MOENNER JEAN-PIERRE
IPC: G01N27/22
Filed: 2002-12-20
Abstract: The invention relates to a device for integrating electrodes characterizing the flow of a multiphase fluid in a tubing. The device includes a tube section made out of an electrically insulating material and bearing the electrodes on its external surface. A  metal compensation sheath encircles the section, being separated from the latter by an insulating and incompressible fluid. An annular chamber outside the sheath communicates with the inside of the tubing. The sheath is fixed on seal rings inserted at the ends of the section, by reinforcement for example.
Patent CA-2474663-A1 (CA)
Title: Method of creating a transaction related record
Inventor: SCHWARZ MIKEL A
IPC: G06Q20/00
Filed: 2003-01-30
Abstract: The invention regards a method of creating a transaction related record and includes communicating (26) selection data to a remote user terminal (24) wherein the selection data provides a user with an option to select payment for the transaction from one of a credit card (30), a telephone, and a bank account (32). The method monitors which particular account type the user selects and receives account data associated with the particular account. Thereafter, account data and an account type identifiers that identifies the account type selected by the user is included in a transaction record (28). The transaction record is then communicating to transaction processing equipment. The invention extends to transaction processing system and to merchant network equipment (2) and transaction processing equipment.
Patent CA-2477860-A1 (CA)
Inventor: VINER VICTOR
IPC: G06Q40/00
Filed: 2003-02-27
Abstract: An investment portfolio management system enables computation of hedging strategies (each including one or more hedging transactions) and presentation of the strategies to the investor. Each hedging strategy takes into consideration tax impact information that is sparticularized to the individual investor. Investor portfolio data identifying assets owned by an investor and tax status information associated with the investor can be stored at a server that is accessible by a web browser. Software at the server enables computing of the hedging strategies based on an analysis of an investor's investment portfolio. The portfolio analysis includes an analysis of at least a first one of the assets identified by the investor portfolio data and a tax impact analysis to determine gain and loss and tax impact data associated with hedging transactions. The determined gain, loss and tax impact data can be determined based on the investor's particular tax status information.
Patent CA-2478843-A1 (CA)
Title: Moteur alternatif et systeme d'injection associe
Inventor: VAN DE LOO PAUL
IPC: F01L11/00
Filed: 2003-03-28
Abstract: L'invention concerne un moteur alternatif et un système d'injection de fluide de travail associé. Le moteur comprend au moins un cylindre (30) dans lequel se trouve un piston à mouvement alternatif (32), et une chambre à volume variable conçue pour recevoir un fluide de travail par l'intermédiaire d'une soupape d'admission (40). Le système d'injection comprend une soupape pilote (34) présentant un état ouvert et un état fermé. A l'état ouvert, le fluide secondaire traverse la soupape pilote de manière à agir sur la soupape d'admission (40). Le système comprend également un moyen d'actionnement (18) conçu pour commander l'état de la soupape pilote (34). La soupape d'admission (40) est conçue pour s'ouvrir en réaction à l'actionne du fluide secondaire. Le moteur peut également comprendre un moyen d'échappement, éventuellement par portage du piston (32) et de la paroi du cylindre. Le fluide de travail peut être utilisé en tant que fluide secondaire.
Patent CA-2480632-A1 (CA)
Title: Drug delivery particle
Inventor: LANPHERE JANEL
IPC: A61K45/00
Filed: 2003-03-28
Abstract: A drug delivery particle including a reservoir region having primarily large pores and a metering region. The particle can be highly spherical.
Patent CA-2480925-A1 (CA)
Title: Compositions comprising retinoids and nondenatured botanical extracts having trypsin-inhibiting activity for treating skin conditions
Inventor: SEIBERG MIRI
IPC: A61K8/00
Filed: 2004-09-09
Abstract: This invention relates to methods and compositions for treating and ameliorating skin conditions including acne, rosacea and wrinkling caused by photodamage or intrinsic aging. More particularly, this invention relates to compositions containing certain natural extracts and natural or synthetic retinoids.
Patent CA-2482124-A1 (CA)
Title: Methods of treatment using an epithelial sodium channel blocker and an inhibitor of the mineralocorticoid receptor
Inventor: BUBIEN JAMES
IPC: A61K31/58
Filed: 2002-04-19
Abstract: Co-administration of a channel blocking epithelial sodium channel (ENaC) blocker in conjunction with a mineralocorticoid receptor inhibitor makes it possible to achieve desired lowering of blood pressure with use in the range of 20% to 75% or less of the presently used dosage of the mineralocorticoid receptor inhibitor (MRI), thus avoiding many of the deleterious side effects usually associated with administration of an MRI. As little as 10% of the usual dosage of MRI may, in some cases, be efficacious. The most commonly used EnaC blocker now in use is amiloride. The most commonly used inhibitors of the mineralocorticoid receptor are precursors of canrenone.
Patent CA-2482334-A1 (CA)
Inventor: ALDERETE JOHN P
IPC: G01N33/543
Filed: 2003-03-27
Abstract: A method and kit for detecting Trichomonas vaginalis infection in a human subject are disclosed. In the method, a body-fluid sample such as a vaginal-swab sample or urine is obtained from the subject and contacted with an antibody specific against a Trichomonas adhesin peptide, forming an anti body-adhesin peptide complex if the subject is infected with Trichomonas.  The presence or absence of the complex establishes, with a reliability of at least 80%, in the case of a vaginal swab sample, and with a reliability of at least 40% in the case of a urine sample, the presence or absence, respectively, of Trichomonas infection in the subject. A preferred test kit employs a dry-strip, sandwich assay, format.
Patent CA-2483202-A1 (CA)
Title: Method of producing hydrocarbon gas
Inventor: VERBEEK PAULUS HENRICUS JOANNE
IPC: E21B43/00
Filed: 2003-04-24
Abstract: A method of producing gas from an underground formation, which is penetrated by a production well to surface, the method comprising allowing formation fluid comprising gas and liquid to flow into the production well at a production interval; allowing the formation fluid to separate into a gaseous component and a liquid component; producing the gaseous component through th e production well to the surface; accumulating the liquid component in the production well so as to form a liquid column having, at a drainage interval of the production well, a pressure exceeding the pressure in the surrounding formation; and allowing liquid from the liquid column at the drainage interv al to drain away into the surrounding formation, comprising treating the wall o f the production well at the drainage interval and/or treating the formation surrounding the drainage interval so as to increase the flow rate of liquid into the surrounding formation.
Patent CA-2484829-A1 (CA)
Title: Methods and compositions for treating tinea versicolor using combinations of retinoids and certain antifungals
Inventor: BIRNBAUM JAY E
IPC: A61K31/203
Filed: 2003-05-08
Abstract: Tinea versicolor is a fungal infection of the skin an often results in a discoloration or dyspigmentation of the infected skin. The present invention provides as a combination therapy an antifungal for treating the fungal infection and a retinoid for correcting the skin pigmentation. Preferred antifungal agents are those which are also CYP-26 inhibitors, which delay th e natural enzymatic breakdown of retinoids in the skin. Alternatively, a non-C YP- 26 inhibiting antifungal can be used in combination with a retinoid, with a CYP-26 inhibitor (antifungal or not) optionally added.
Patent CA-2488954-A1 (CA)
Title: Prosthesis graft with z pleating
Inventor: HOWAT WILLIAM L
IPC: A61F2/06
Filed: 2004-11-29
Abstract: A prosthesis configured for establishing a fluid flow path through an artery or the like includes a generally cylindrical body portion formed from graft materia l. In accordance with a preferred aspect of the invention, at least a portion of t he graft material is profiled where the profile defines a geometric pattern, e.g. a series of Z pleats.
Patent CA-2490436-A1 (CA)
Title: Hand-held analytical device
Inventor: HUEBNER UTE
IPC: G01N33/487
Filed: 2004-12-16
Abstract: The invention relates to a portable hand-held analytical device for analysis of a medically significant component of a sample, with a housing (2) having a loading opening (4) for receiving a replaceable drum cartridge (5) containing analytical consumables (8), whereby the housing (2) comprises on an outer side a dispensing opening (7) through which the consumables (8) can be pushed by means of the removal facility (45). The invention provides for the loading opening (14) to be closeable by means of a lid (13), which upon closing effects a linear motion of a pushing part (27) which moves the drum cartridge (5) to a working position, in which it can be rotated about its geometric longitudinal axis.
Patent CA-2495312-A1 (CA)
Inventor: SHINKADO HIROAKI
IPC: D04H3/04
Filed: 2003-08-01
Abstract: L'invention concerne la production d'une feuille de fibres renforcées par l'ouverture de fibres pleines. Cette feuille est utile en tant que matière de renforcement pour une matière composite renforcée par des fibres. L'invention concerne un appareil d'ouverture de fibres, qui permet d'obtenir en douceur une feuille de fibres ouvertes, à partir de fibres pleines de fibres renforcées. Selon l'invention, une partie d'ouverture de fibres (25) est dotée d'éléments de support (254) agencés dans une configuration en forme de plan ou en forme d'arc, à des intervalles déterminés, le long d'une direction de déplacement d'une fibre unique ou de fibres pleines, et des fibres sont ouvertes par du fluide, du côté situé à proximité des éléments de support (254) et du côté éloigné des éléments de support (254). Ainsi, l'efficacité d'ouverture de fibre est améliorée. Les domaines d'application de l'invention sont l'aérospatial, le transport terrestre, la navigation, l'architecture, le génie civil, les pièces industrielles, les articles de sport etc.
Patent CA-2502818-A1 (CA)
Title: Garment for motorcyclists with improved comfort
Inventor: MAZZAROLO GABRIELE
IPC: A41D13/02
Filed: 2003-10-29
Abstract: Elastic inserts (15, 25) are incorporated in selected zones such as the legs and arms of an article of garment for motorcyclists, for example a leather suit, said inserts having a shape and manner of application such that the configuration of the garment in the rest condition corresponds to the position of the person wearing the garment when riding a motorcycle, but also allows said person to move freely when not sat in the saddle of the motorcycle.