baber/WOPTO huggingface dataset:
Patent CA-2457131-A1 (CA)
Inventor: YASHPAL KIRAN
IPC: A61K38/00
Filed: 2001-08-17
Abstract: La présente invention concerne des procédés permettant d'administrer des oligonucléotides, des analogues de nucléotides et des composés de blocage non nucléotidiques afin de moduler la voie biosynthétique du récepteur NK-1 chez les humains et d'autres mammifères. L'invention se rapporte également à des oligonucléotides, et en particulier à des oligonucléotides antisens complémentaires des acides nucléiques de la voie qui produit le récepteur NK-1, et complémentaires des acides nucléiques des voies qui régulent la production et la fonction du récepteur NK-1, qui sont utilisés, entre autres, pour soulager la douleur, l'inflammation et les effets indésirables de nombreux états et maladies dans lesquels interviennent les récepteurs NK-1. L'invention concerne des composés perturbateurs non nucléotidiques et des composés analogues des nucléotides qui agissent comme modulateurs de la voie biosynthétique du récepteur NK-1 et régulent la production et la fonction du récepteur NK-1, et qui sont utilisés aux mêmes fins que celles mentionnées ci-dessus. L'invention concerne enfin des préparations pharmaceutiques destinées aux humains et à d'autres mammifères, qui contiennent un ou plusieurs oligonucléotides, analogues de nucléotides ou composés perturbateurs non nucléotidiques.
Patent CA-2457624-A1 (CA)
Inventor: GERMANO CARL
IPC: A61K31/122
Filed: 2002-08-09
Abstract: L'invention concerne un additif nutritionnel permettant de traiter des maladies débilitantes chroniques, telles que le VIH/SIDA, de manière à maîtriser des états de stress oxydatif, de masse musculaire maigre réduite, de production d'énergie réduite (défaillance mitochondriale) et de soutenir la fonction immunitaire. Cet additif comprend une superoxyde dismutase (SOD) pouvant être administrée oralement, de préférence SOD/GLIADIN, en combinaison avec d'autres composants de soutien antioxydants/immunitaires (des bêta-glucanes, des nucléotides, des polyphénoles de fruit); du lactosérum à immunoglobine élevée; (lactosérum non dénaturé), de l'alpha cétoglutarate d'ornithine (OKG), des amino acides à chaînes ramifiées et de la glutamine permettant de réduire une perte de la masse musculaire maigre; ainsi que de la Coenzyme Q10, du D-Ribose et de la L-Carnitine permettant d'apporter un soutien d'énergie (réduction de défaillance mitochondriale).
Patent CA-2461325-A1 (CA)
Title: Intake apparatus for engine
Inventor: NAKAGOME HIROSHI
IPC: F02D9/02
Filed: 2004-03-16
Abstract: In an intake duct, a first intake passage arranged in a width direction of the front wheel and a second intake passage arranged on a side of the first intake passage are formed such that a flow area of the first intake passage is set larger than a flow area of the second intake passage. An intake control valve closes the first intake passage when the engine rotates at low speed and opens the first intake passage when the engine rotates at high speed.
Patent CA-2469534-A1 (CA)
Inventor: REINHEIMER ARNE
IPC: C09K21/04
Filed: 2004-06-01
Abstract: The method of at least one thermally expandable graphite intercalation compound, containing A) a least one metal halide of at least one of the elements Fe, Al, Sb, Zn, Y, Cr and Ni and B) at least one nitroalkane of the general formula CH3(CH2)n NO2, in which n is a whole number from 0 to 10, as well as its structural isomers or mixtures, as intumescing, fire-protection additive in polymer matrices for producing intumescing fire-protective seals for through holes, wall bushings and other openings in walls, floors and/or ceilings of buildings, as well as a method for preparing the thermally expandable graphite-intercalation compounds used.
Patent CA-2470302-A1 (CA)
Title: Edge and corner for a table top
Inventor: STRONG CURTIS L
IPC: B29C49/00
Filed: 2003-04-09
Abstract: A table (1) includes a table top (12) with an upper surface (14) and a lower surface (16). The table top (12) is preferably constructed from blow-molded plastic and it includes a generally hollow interior. The table top (12) includes downwardly extending lip (28), one or more strengthening members th at are integrally formed in the lip. The lip (28) is desirably integrally forme d in the table top as part of a unitary structure and the lip (28) includes a generally hollow interior that is integrally formed during the blow-molding process with the generally hollow interior of the table top. Advantageously, the table top (12) may include a plurality of depressions (30) that are integrally formed in the table top and the strengthening members may be generally aligned with at least some of the depressions (30). The strengthening members include one or more of inwardly extending portions (216), outwardly extending portions (218) and/or ribs (220) that increase a thickness of the lip. The strengthening members may also be formed in a corn er of the table top.
Patent CA-2470638-A1 (CA)
Inventor: YOAKIM ALFRED
IPC: A47J31/06
Filed: 2003-01-13
Abstract: L'invention concerne une capsule fermée conçue pour être vidée sous pression dans un dispositif d'extraction. Cette capsule fermée contient une substance (43) pour la préparation d'une boisson. Par ailleurs, cette capsule fermée comprend un système fermé (44, 45) contenant ladite substance et un moyen (46, 48), situé à l'intérieur dudit système, qui permet d'ouvrir ladite capsule lors de son utilisation et laisse couler (49) ladite boisson, sans qu'elle entre en contact avec son système d'extraction.
Patent CA-2471037-A1 (CA)
Title: Aberrometer illumination apparatus and method
Inventor: MARTINO RONALD J
IPC: A61B3/10
Filed: 2002-12-13
Abstract: A wavefront-sensing device for measuring ocular aberrations includes, among other things, a retinal illumination component and a wavefront imaging component (e.g., a microlens array for a Shack-Hartmann wavefront sensor). The retinal illumination component includes a laser source and a fixed collimating lens. In one embodiment, an improved device has a beam path between the retinal illumination component and the patient's eye containing no refracting, diffracting, or phase altering components for focusing the illumination beam on the retina. In another embodiment, the retinal illumination component provides a beam having a diameter on the retina that is smaller than the diffraction limit of the wavefront imaging component over a refractive focus range of the patient's eye of between about -12D to +6D.
Patent CA-2471735-A1 (CA)
Inventor: YAMADA AKIRA
IPC: A61P35/00
Filed: 2002-08-28
Abstract: Allergic reaction suppressors comprising a peptide which originates in the same antigenic substance as the antigenic substance inducing the allergic reaction, contains an epitope different from the epitope participating in th e induction of the allergic reaction and yet does not induce the allergic reaction; preventives and/or remedies or medicinal compositions for type I allergic diseases containing the above suppressors; a method of suppressing allergic reactions, a desensitizing method, and a method of preventing/treating type I allergic diseases with the use of the same; a cancer vaccine containing a tumor rejection antigen-origin peptide which has a cytotoxic T lymphocyte inducing activity but inducing an allergy reaction an d another peptide which originates in the same antigen as the above peptide, h as an epitope different from the epitope of the above peptide and exhibits an effect of suppressing the allergic reaction; remedies for cancer containing the above vaccine; and a method of treating cancer with the use of the vacci ne.
Patent CA-2473965-A1 (CA)
Title: Tire pressure monitoring method
Inventor: STACER DARYL J
IPC: B60C23/00
Filed: 2002-11-26
Abstract: A method of monitoring the fluid pressure of, with a sensor of a tire pressu re management system disposed without, a tire that prevents overinflation of same. The method of monitoring a fluid pressure of a tire with a sensor, disposed in conduit assemblies for conducting fluid to or from the tire, of a tire pressure management system includes providing a pulse of compressed flu id to the conduit assemblies, unless a counter exceeds a count, the fluid in th e conduit assemblies thereafter having a conduit pressure. The pulse has a duration that corresponds to a ratio defined by a first predetermined amount divided by a second predetermined amount.
Patent CA-2475401-A1 (CA)
Title: Method for the preparation of citalopram
Inventor: SVANE HENRIK
IPC: C07D307/87
Filed: 1999-11-22
Abstract: The S-enantiomer of a compound of Formula IV      wherein R is halogen, or CF3-(CF2)n-SO2-O, n being 0 to 8, as the base or a pharmaceutically acceptable salt thereof.
Patent CA-2475477-A1 (CA)
Title: Method for making tissue product containing carboxylated cellulosic fibers
Inventor: WINSLOW ALAN R
IPC: D21F11/14
Filed: 2004-07-22
Abstract: A tissue product having two or more layers, with at least one layer including carboxylated cellulosic fibers. Methods for making the tissue product.
Patent CA-2479288-A1 (CA)
Title: Process for producing cytotoxic lymphocyte
Inventor: SAGAWA HIROAKI
IPC: A61K35/26
Filed: 2003-03-25
Abstract: The present invention relates to a method for preparing a cytotoxic lymphocyte characterized in that the method comprises the step of carrying out at least one of induction, maintenance and expansion of a cytotoxic lymphocyte in the presence of fibronectin, a fragment thereof or a mixture thereof.
Patent CA-2479356-A1 (CA)
Title: Building additives based on purified hydroxyalkyl guar
Inventor: RINALDI CRISTINA
IPC: C08B37/00
Filed: 2003-03-12
Abstract: The present invention relates to highly hydroxyalkylated, glyoxal crosslinke d, purified hydroxyalkyl guar useful as additive in the building industry, and to a method for its preparation.
Patent CA-2482499-A1 (CA)
Title: Aerosol contenant une substance active particulaire
Inventor: WALKER STEPHEN ERNEST
IPC: A61P3/10
Filed: 2003-04-15
Abstract: La présente invention concerne des substances actives se présentant sous forme particulaire, ainsi que des préparations contenant ces substances actives en suspension dans des véhicules liquides non solvants. Les préparations selon cette invention présentent un meilleur pouvoir de floculation et sont notamment utilisées en tant que préparations aérosols mises en oeuvre, par exemple, dans des aérosols doseurs.
Patent CA-2486686-A1 (CA)
Title: Tuyau ou boyau a air comprime hivernal
Inventor: OUELLET PAULO
IPC: F16L53/38
Filed: 2004-12-20
Abstract: L'invention d'un tuyau à air comprimé hivernal concerne l'utilisation d e tuyau a air comprime (1) à des températures sous le point de congélation (0 degré celcius et moins) donc en période hivernale. Cette invention empêchera la condensation de l'humidité à l'intérieur des tuyaux rendant l'utilisation de ceux-ci inopérantes ou inefficaces. De plus cette invention permettra au tuyau de rester flexible à basse température. De plus les poignés de l'outil utilisé et les raccords resteront eux-aussi à une température acceptable. Grâce à l'installation d'un fils chauffant (2) selon une nouvelle technique, l'air comprimé à l'intérieur du câble se maintiendra à une température au-dessus du point de congélation et rendra possible l'utilisation de ces câbles malgré les températures extrêmes de nos hivers.
Patent CA-2486802-A1 (CA)
Inventor: APEL BRUCE P
IPC: H01R13/533
Filed: 2003-05-23
Abstract: A connector includes a first housing section having a plurality of electrically conductive contacts therein. The connector also includes a second housing section including a plurality of electrically conductive contacts that can form an electrical connection with the contacts of the first housing section. The first housing section and the second housing section are removably connectable and are capable of forming an explosion proof or flame proof housing when connected. The contacts of at least one of the second housing section and the first housing section are movable relative to their respective housing section to align the contacts of the second housing and the contacts of the first housing section during connection of the second housing section to the first housing section. Electrically conductive connection between the contacts of the first housing section and the contacts of the second housing section occurs during connection such that when connection between the contacts of the first housing section and the contacts of the second housing section occurs, the first housing section and the second housing section are in sufficient connection to form an explosion proof housing.
Patent CA-2486894-A1 (CA)
Inventor: BRAND PETER JOHN
IPC: A61M15/00
Filed: 1998-06-08
Abstract: An aerosol container assembly includes an aerosol container containing a medicament and having an outlet member for dispensing metered doses of the medicament from the container, the outlet member dispensing a metered dose upon each actuation of the outlet member, and a dose indicating device having a dose indicator adapted to indicate the number of metered doses of medicament dispensed from or remaining in the container after each actuation of the outlet member. The dose indicating device tightly connects to the container in the vicinity of the outlet member. The ability to be able to identify the number of doses dispensed or the number remaining is a significant advantage.
Patent CA-2490260-A1 (CA)
Title: A system and method for determining physical location of a node in a wireless network during an authentication check of the node
Inventor: WHITE ERIC D
IPC: G06F21/62
Filed: 2003-07-28
Abstract: A system and method for providing security to a wireless network by using a mobile node's location as a parameter for deciding if access is to be given to the node. The system and method employ access points, wireless routers and mobile nodes, each including at least one transceiver adapted to transmit and receive communication signals to and from other wireless routers, mobile nodes and other mobile access points. Each access point is connected to a network management system which allows enhanced network monitoring and control. Each network node includes technology which may determine an absolute node location containing latitude, longitude and altitude of a node, or a relative node location containing the distance and angle between nodes, or a combination of both absolute and relative location data.
Patent CA-2491306-A1 (CA)
Title: Detergent cosmetic composition comprising anionic and amphoteric surfactants, a strongly charged cationic polymer and a water-soluble salt
Inventor: SIMONET FREDERIC
IPC: A61K8/40
Filed: 2004-12-20
Abstract: Detergent cosmetic composition comprises an anionic surfactant (I), an amphoteric surfactant (II), a cationic polymer with a cationic charge density of more than 5 meq/g and at least 1 wt.% of a water-soluble salt, where the (I)/(II) weight ratio is no more than 1 and the total surfactant content is no more than 18 wt.%. Detergent cosmetic composition comprises an anionic surfactant (I), an amphoteric surfactant (II), a cationic polymer with a cationic charge density of more than 5 meq/g and at least 1 wt.% of a water-soluble salt, where the (I)/(II) weight ratio is no more than 1 and the total surfactant content is no more than 18 wt.%. (II) is a (C8-C24)alkylamido(C3-C8)alkyl betaine, a sulfobetaine, a (C8-C24)alkylamido(C3-C8)alkyl sulfobetaine, a (C8-C24)alkylamphodiacetate, a (C8-C24)alkylamphomonopropionate, a (C8-C24)alkylamphodipropionate of a phosphobetaine. An independent claim is also included for cosmetic treatment of keratinic materials by applying a composition as above and rinsing it off.
Patent CA-2495434-A1 (CA)
Title: Test tube with lid opening mechanism
Inventor: GARVIN ROY
IPC: B01L3/14
Filed: 2003-08-19
Abstract: A novel microtube is provided comprising: a container having an open end defining an opening for receiving materials to be contained, and a closed en d; a lid adapted to make closing contact with the opening of the container; wherein the lid is provided with a flange extending outwardly therefrom, and arranged to move towards the closed end of the container upon application of a mechanical force to a surface of the flange so as to remove the closing contact, whereby the container is opened.
Patent CA-2496325-A1 (CA)
Title: Phenacyl xanthine derivatives as dpp-iv inhibitor
Inventor: MAIER ROLAND
IPC: C07D473/06
Filed: 2003-08-16
Abstract: The invention concerns substituted xanthines of general formula (I), wherein:  R1 to R4 are such as defined in Claim 1, and tautomers, stereoisomers, mixtures, prodrugs and salts thereof. Said compounds have advantageous pharmacological properties, in particular an inhibiting effect on the activity of the dipeptidyl peptidase IV (DPP-IV) enzyme.
Patent CA-2497602-A1 (CA)
Title: Stent with rough surface and its manufacture
Inventor: VON OEPEN RANDOLF
IPC: A61F2/91
Filed: 2003-09-22
Abstract: A stent is provided wherein at least an outer surface portion is roughened to a predetermined extent and wherein a drug or a therapeutic agent can be applied to said surface. This results in an improved stent, which can be manufactured at low costs and which can further avoid thrombus formation and a stenosis.
Patent CA-2499224-A1 (CA)
Title: Optical packet routing network system based on optical label switching technique
Inventor: MATSUOKA MORITO
IPC: H04L45/60
Filed: 2000-08-24
Abstract: An optical communication equipment comprises shared optical sources to be shared by communication nodes, the wavelengths of optical signals are converted into desired wavelengths according to the addressed information of the corresponding optical label signals by using the shared optical sources, and routed to the addressed communication nodes without being converted into electrical signals by using the wavelength routing function of the cyclic-wavelength arrayed-waveguide grating (AWG). The load of each communication node can be reduced by incorporating the multi-wavelength optical sources, which can be shared among individual communication nodes, into the router.      Further, each communication node is provided with an optical gate or the like for returning the optical signal to the communication node from which the optical signal ha been transmitted through the router in order to adjust the transmission time lag between the optical signal and the corresponding optical label signal by the controllers. In this way, the setting of the transmission time lag by each communication node can be made easier, thereby largely reducing the work load.
Patent CA-2500108-A1 (CA)
Inventor: NAGAO MAMORU
IPC: C22C38/54
Filed: 2003-09-24
Abstract: L'invention concerne une tige de fil métallique laminé à chaud d'au moins 5,0 mm de diamètre, comprenant : entre 0,6 et 1,0 % de C (en termes de % en poids, applicable ici) ; entre 0,1 et 1,5 % de Si, et entre 0,3 et 1,0 % de Mn, P étant limité à 0,02 % ou moins et S étant limité à 0,02 % ou moins et où au moins 90 % de la surface sont à base de structure de perlite. Ladite tige de fil métallique laminée à chaud manifeste, à une longueur de 4 m, des propriétés mécaniques satisfaisant à : (1) TS*-30 = moyenne de résistance à la traction (TSav :MPa) = TS*+30, où TS* = 400x{[C]+([Mn}+[Si])/5}+670 où [] désigne le titrant (%) de chaque élément ; (2) écart normalisé de la résistance à la traction (TS sigma )= 30 MPa ; (3) moyenne de réduction de la zone de rupture (RAav) > 35 %, et (4) écart normalisé de réduction de la zone de rupture (RA sigma )= 4 %. Cette tige de fil métallique laminée à chaud présente d'excellentes qualités de tréfilage, uniquement par laminage à chaud, même lorsque le traitement thermique tel que le patentage est évité et permet, comparativement à des tiges conventionnelles, de réduire la fréquence de rupture de fils métalliques.
Patent CA-2500186-A1 (CA)
Inventor: GLADNEY RICHARD F
IPC: A47C20/04
Filed: 2003-09-29
Abstract: L'invention concerne un matelas possédant un point de fixation à un cadre de lit réglable qui fournit un point de pivot autour duquel le matelas peut pivoter lorsqu'on le soulève dans une position inclinée. Dans un mode de réalisation, le matelas comprend un point pivotant s'étendant transversalement au matelas et fournit un point de pivot autour duquel une partie du matelas peut pivoter par rapport à une autre partie dudit matelas. Le placement d'un élément environ à mi-chemin sur le matelas, permet le pivotement d'une moitié du matelas par rapport à l'autre moitié, le point central dudit matelas étant maintenu en place. Du fait de la fixation de l'élément au cadre, le centre du matelas est maintenu par rapport audit cadre même lorsque une partie du matelas est inclinée par rapport à l'autre, ce qui permet d'empêcher le soulèvement du matelas par rapport au cadre ou d'améliorer sa tendance à se soulever lorsque ledit cadre pivote dans une position inclinée.
Patent CA-2500510-A1 (CA)
Title: Methods of conducting promotional contests and beverage containers for use therein
Inventor: ROSENFELD ARON M
IPC: G06Q30/02
Filed: 2003-09-29
Abstract: A method of conducting a promotional contest by providing a portal that establishes a field for detecting the presence of a field-disturbing element, providing packages respectively having and lacking a concealed field-disturbing element, and distributing the packages randomly to different individuals who carry the packages past the portal so that a package with a field-disturbing element causes the portal to produce a signal indicating a winner of the contest. A can for beverages or the like having a field-disturbing element concealed thereon, for use in such a promotional contest.  The element may be mounted in a peelable foil closure member covering an aperture in the can lid.
Patent CA-2502220-A1 (CA)
Title: Transdermal patch for external use comprising fentanyl
Inventor: TATEISHI TETSURO
IPC: A61K31/4468
Filed: 2003-10-17
Abstract: A transdermal patch for external use having a substrate and a pressure- sensitive adhesive layer formed on one face of the substrate, which contains polyisobutylene, a mineral oil and fentanyl employed as the active ingredien t in the pressure-sensitive adhesive layer and in which the contents of polyisobutylene and fentanyl in the pressure-sensitive adhesive layer respectively range from 75.2 to 94.2% by mass and 1 to 6% by mass while the content of the mineral oil is from 0.25 to 0.05 parts by mass based on polyisobutylene. This patch can be easily produced, has a long-lasting effec t and is excellent in stickiness to the skin and follow-up properties.
Patent CA-2506230-A1 (CA)
Inventor: ZHOU ZHAO
IPC: C07K16/24
Filed: 2003-11-10
Abstract: A method of using IL-6 antagonists to treat pathological processes associate d with proliferative diseases, such as cancer, by specifically preventing or inhibiting the ability of new tissue to develop a blood supply. The inventio n more specifically relates to methods of treating such diseases by the use of IL-6 antagonists such as antibodies directed toward IL-6, including specifie d portions or variants, specific for at least one Interleukin-6 (IL-6 also kno wn as interferon .beta.2) protein or fragment thereof, in an amount effective t o inhibit angiogenesis.
Patent CA-2507100-A1 (CA)
Title: 2,4,6-trisubstituted pyrimidines as phosphotidylinositol (pi) 3-kinase inhibitors and their use in the treatment of cancer
Inventor: RENHOWE PAUL A
IPC: A61K31/506
Filed: 2003-11-21
Abstract: Compounds having formula I are provided where the variables have the values described herein.   (see formula I) Pharmaceutical formulations include the compounds or pharmaceutically acceptable salts thereof and a pharmaceutically acceptable carrier and combinations with other agents. A  method of treating a patient comprises administering a pharmaceutical formulation according to the invention to a patient in need thereof.