Patent SG-11201902938T-A (SG)
Title: Compounds, devices, and uses thereof
Inventor: VEISEH OMID
IPC: C07D409/06
Filed: 2017-10-03
Abstract: International Patent Classification: C07D 401/14 (2006.01) C07D 409/14 (2006.01) C07D 405/14 (2006.01) C07D 413/04 (2006.01) C07D 401/04 (2006.01) C07D 401/10 (2006.01) C07D 401/12 (2006.01) C07D 403/04 (2006.01) C07D 405/04 (2006.01) C07D 405/06 (2006.01) CO7D 405/12 (2006.01) CO7D 409/06 (2006.01) CO7D 417/06 (2006.01) CO7D 417/14 (2006.01) CO7D 249/04 (2006.01) CO7D 249/06 (2006.01) CO7D 471/04 (2006.01) CO7D 487/04 (2006.01) A61K 31/4192 (2006.01) A61P 37/00 (2006.01) (21) International Application Number: PCT/US2017/055001 (22) International Filing Date: (25) Filing Language: (26) Publication Language: (30) Priority Data: 62/403,554 62/403,548 62/403,532 62/403,559 62/403,543 62/403,556 62/403,538 62/436,832 03 October 2017 (03.10.2017) English English 03 October 2016 (03.10.2016) US 03 October 2016 (03.10.2016) US 03 October 2016 (03.10.2016) US 03 October 2016 (03.10.2016) US 03 October 2016 (03.10.2016) US 03 October 2016 (03.10.2016) US 03 October 2016 (03.10.2016) US 20 December 2016 (20.12.2016) US (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 12 April 2018 (12.04.2018) Hu omits I iolo ol !MEM H 111110#1111 (10) International Publication Number WO 2018/067615 Al WIPO I PCT OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: as to applicant's entitlement to apply for and be granted a patent (Rule 4.17(ii)) as to the applicant's entitlement to claim the priority of the earlier application (Rule 4.17(iii)) Published: with international search report (Art. 21(3)) W O 20 18/067 6 15 Al (71) Applicant: SIGILON THERAPEUTICS, INC. [US/US]; 161 First Street, Suite 2c, Cambridge, MA 02142 (US). (72) Inventors: VEISEH, Omid; 4903 Palmetto St., Bellaire, TX 77401 (US). HEIDEBRECHT, Richard; 222 Wil- low Ave #2, Somerville, MA 02144 (US). WOTTON, Paul, Kevin; 221 Columbus Ave #602, Boston, MA 02116 (US). OBERLI, Matthias; 4 Rollins Court, Cambridge, MA 02139 (US). MILLER, Robert, James; 120 North- ridge Drive, East Bridgewater, MA 02333 (US). (74) Agent: LARKIN, Angelyn; Lando & Anastasi, LLP, Riverfront Office Park, One Main Street, Suite 1100, Cam- bridge, MA 02142 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, (54) Title: COMPOUNDS, DEVICES, AND USES THEREOF (57) : The present invention provides compounds, e.g., compounds of Formula (I) and pharmaceutically acceptable salts, solvates, hydrates, tautomers, stereoisomers, isotopically labeled derivatives, and compositions thereof. Also provided are implantable elements (e.g., devices and materials) comprising the same, as well as methods of use thereof, e.g., for treating or preventing a disease, disorder, or condition.