baber/WOPTO huggingface dataset:
Patent CA-2909706-A1 (CA)
Inventor: WADSWORTH SAMUEL
IPC: A61P27/02
Filed: 2014-04-17
Abstract: Compositions and methods for treating macular degeneration are disclosed. The methods utilize IL17 inhibitors, such as IL17 receptors, as well as fusion proteins including an IL17 receptor fused with a multimerization domain, and recombinant viral vectors encoding such fusions.
Patent CA-2909953-A1 (CA)
Title: Liquid-dispensing pad
Inventor: SOLLMANN HENNER
IPC: B05C1/06
Filed: 2015-10-22
Abstract: The invention relates to a liquid-dispensing pad, comprising a liquid-impervious rear wall (2) composed of plastic, a front wall composed of a perforated elastic film (3) that is connected to the rear wall (2) by a weld (4), and a liquid-retaining core (5) between the front wall and the rear wall (2).  According to the invention, the elastic film (3) is a coextruded film having an elastic layer (9) and an inelastic cover layer (8), the cover layer (8) forming a surface of the liquid-dispensing pad and being composed of polyolefin, the thickness of the cover layer (8) being less than 10 µm and the thickness ratio of the elastic layer (9) to the cover layer (8) at least 10:1. The invention further relates to a disinfecting device comprising the liquid-dispensing pad and a support. To be published with FIG. 3.
Patent CA-2911382-A1 (CA)
Title: Butadien2,3-diyl linked di-dopo derivatives as flame retardants
Inventor: ANGELL SCOTT EDWARD
IPC: C09K21/12
Filed: 2014-05-02
Abstract: Disclosed are novel, halogen-free flame-retardants derived from 9,10-Dihydro-9-Oxa-10-Phosphaphenantrene-10-oxide (DOPO) of the structure below: This invention also relates to the use of the halogen free DOPO derived compositions as flame-retardants in polymers, and a process of preparing the above compounds by reacting a formula A compound with a formula B compound:
Patent CA-2914063-A1 (CA)
Inventor: DELLINGER JOSEPH ANTHONY
IPC: G01V1/00
Filed: 2014-10-15
Abstract: There is taught herein a system and method for creating an improved seismic source signal by applying a feedback mechanism, active adaptive control, to perturb a resonator device configuration on the fly so as to ensure that the overall trajectory of the sweep is correctly produced, even though the precise details of each oscillation of the source are still not constrained. An embodiment teaches a method for adjusting the squeeze piston or tow depth of a resonant piston seismic source to bring the resonant frequency to a desired value. As a consequence, the resulting seismic signal is improved as compared with seismic signals acquired via resonators that do not utilize the instant teachings.
Patent CA-2916980-A1 (CA)
Inventor: LATHAM JOHN A
IPC: C07K16/18
Filed: 2014-07-03
Abstract: The present disclosure provides methods for the prevention or treatment of metabolic disorders. In exemplary embodiments, methods of administering an anti-CGRP antibody are provided, optionally in combination with a second agent, wherein peripheral and/or hepatic glucose utilization is increased, thereby preventing or treating diseases and disorders associated with insulin resistance. Compositions comprising an anti-CGRP antibody are also provided, optionally in combination with a second agent, which are suitable for administration to increase peripheral and/or hepatic glucose utilization and thereby prevent or treat diseases and disorders associated with insulin resistance.
Patent CA-2917885-A1 (CA)
Inventor: LAZAROF SARGON
IPC: A61C19/08
Filed: 2014-07-07
Abstract: Disclosed are applicators and methods injecting of a liquid anesthetic into a dental patient with no or minimal pain. In accordance with one embodiment the applicator is for intraligamentary injection and includes an elongated, thin member having an open distal free formed of a resilient and somewhat conformable material suitable for producing a substantially fluid-tight interface with the anatomic structures at the gingival sulcus to inject the anesthetic therein. In another embodiment the applicator includes a flexible skirt surrounding a sharpened cannula, with the cannula being movable with respect to the skirt. The skirt is arranged to receive the anesthetic to anesthetize the gum, whereupon the cannula can then pierce the gum to inject the anesthetic into the underlying anatomic structure.
Patent CA-2918047-A1 (CA)
Title: Valise de voyage pliable roulante
Inventor: MCGUIRE BRIAN J
IPC: A45C5/14
Filed: 2016-01-19
Abstract: Un sac de voyage sur roulettes comprend un couvercle couplé à une base, cette dernière comprenant un premier côté opposé à un second côté et une face inférieure sétendant entre les deux, ainsi quune première et une deuxième roue couplées à la base, celles-ci étant configurées pour tourner autour dun axe de rotation et séparées par une première distance le long de laxe de rotation. Au moins une partie de chacune des première et deuxième roues fait saillie à partir du premier côté et de la face inférieure. Une troisième et une quatrième roue couplées à la face inférieure sont configurées pour pivoter indépendamment autour dun axe de pivotement respectif et séparées par une seconde distance sétendant entre les axes de pivotement. Lorsque le sac de voyage sur roulettes est en position verticale, les première, deuxième, troisième et quatrième roulettes sont toutes en contact avec une surface sur laquelle repose le sac de voyage.
Patent CA-2922102-A1 (CA)
Title: Actuation of coloured luminaires for the brightness channel
Inventor: SCHEVARDO DIRK-ACHIM
IPC: F21S10/02
Filed: 2016-02-29
Abstract: A lighting arrangement (2) having a control input (4) for a control variable (6) and having a luminaire (10) as a multicoloured luminaire having an input interface (14b) for a colour variable (16) and a brightness variable (20) contains a control unit (24) having an output interface (14a) for the colour variable (16) and the brightness variable (20), wherein the control unit (24) assigns a brightness value (22) and a colour value (18) to a received control value (8) on the basis of a mapping rule (26). A vehicle (52) contains such a lighting device (2). A method for converting a vehicle (52) having a light control infrastructure (56) for connecting luminaires (10) to a control output (58) for a single control variable (6) involves such a lighting device (2) being connected to the control output (58).
Patent CA-2926773-A1 (CA)
Inventor: DESHPANDE PRASAD KESHAV
IPC: A61P31/00
Filed: 2014-10-10
Abstract: Compound of Formula (I), its preparation and use in preventing or treating bacterial infection is disclosed. Formula (I)
Patent CA-2928248-A1 (CA)
Inventor: HASEGAWA YUICHI
IPC: G09G5/391
Filed: 2014-12-11
Abstract: Provided is an image display system which displays a wide viewing angle image while suppressing VR sickness. When the viewing angle FOVO of an original image provided from an image output device (200) is greater than the viewing angle FOVD of an image observed by a user wearing an image display device (300), the image output device (200) cuts out a viewing angle FOVD from the original image and sends this to the image display device (300). Further, when the viewing angle FOVD of the image observed by the user wearing the image display device (300) is greater than or equal to the viewing angle FOVO of the original image provided from the image output device (200), the image output device (200) sends the original image as-is to the image display device (300).
Patent CA-2932301-A1 (CA)
Title: Agent prophylactique et therapeutique contre le trouble de deficit d'attention avec hyperactivite
Inventor: TOGASHI HIROKO
IPC: A61K31/343
Filed: 2014-12-15
Abstract: L'invention est liée au fait que le 1-(benzofuran-2-yl)-2-propylaminopentane ou l'un des sels d'addition acide pharmacologiquement acceptables de celui-ci est déjà connu pour présenter une excellente activité et un excellent effet en tant qu'antidépresseur, psychotrope, antiparkinsonien et anti-Alzheimer. Cependant, le fait que le composé est efficace dans le traitement prophylactique ou thérapeutique du trouble de déficit d'attention avec hyperactivité (TDAH) est réellement inconnu. La présente invention concerne la nouvelle découverte selon laquelle le 1-(benzofuran-2-yl)-2-propylaminopentane ou l'un des sels d'addition acide pharmacologiquement acceptables de celui-ci est efficace dans le traitement prophylactique ou thérapeutique du trouble de déficit d'attention avec hyperactivité (TDAH). Le résultat est la réalisation de la présente invention.
Patent CA-2932759-A1 (CA)
Inventor: GUINEY CHRISTOPHER A
IPC: G06Q20/40
Filed: 2014-12-05
Abstract: La présente invention concerne des procédés et des systèmes de réception d'une demande d'autorisation associée à une transaction, la demande d'autorisation comprenant un code de compte ; de réception d'un code d'utilisateur à associer au code de compte ; d'association du code de compte et du code d'utilisateur l'un à l'autre de sorte à former un code de compte de paiement ; de détermination d'un identifiant de compte correspondant au code de compte de paiement ; de détermination de l'opportunité de mettre en correspondance le code de compte de paiement avec un numéro de compte primaire (PAN) ; de mise en correspondance, en réponse à la détermination selon laquelle le code de compte de paiement doit être mis en correspondance avec le PAN, du code de compte de paiement au PAN de sorte à déterminer un PAN correspondant au code de compte de paiement ; et d'envoi de la demande d'autorisation comprenant le PAN devant être autorisé.
Patent CA-2933042-A1 (CA)
Inventor: GUPTA MANJU
IPC: C12N15/82
Filed: 2015-01-23
Abstract: Provided are constructs and methods for expressing a transgene in plant cells and/or plant tissues using Zea mays chlorophyll a/b binding gene regulatory elements.
Patent CA-2934248-A1 (CA)
Title: Paliers de butee pour pompes centrifuges
Inventor: GULATI MANMOHAN SINGH
IPC: F04D1/06
Filed: 2014-12-08
Abstract: Ensemble palier pour pompe centrifuge configuré pour s'adapter à une poussée axiale vers l'avant et inverse, et pour être lubrifié par un fluide de traitement. Une pompe renfermant un ensemble à deux paliers qui est lubrifié par un fluide de traitement et qui se situe entre les deux derniers étages d'impulseur de la pompe. Un système de dessalement comprend une pompe dotée d'une entrée pour l'eau de mer à une première extrémité, d'une sortie pour rejeter l'eau de mer à pression élevée à une seconde extrémité, d'un ou de plusieurs impulseurs accouplés à un arbre rotatif entre la première extrémité et la seconde extrémité pour augmenter une pression de l'eau de mer, et d'un ensemble palier lubrifié par l'eau de mer pour absorber la poussée axiale dans les deux directions le long de l'arbre.
Patent CA-2937660-A1 (CA)
Inventor: ADDEPALLI MURALI KRISHNA
IPC: A61K38/20
Filed: 2015-02-20
Abstract: L'invention concerne (entre autres choses) un procédé d'administration à un patient souffrant d'un cancer, le procédé comprenant les étapes d'administration de : (a) une quantité activant IL-2Rß d'un agoniste sélectif de IL-2Rß à action longue ; et (b) une quantité inhibant la voie de CTLA-4 d'un anticorps anti-CTLA-4 ou une quantité inhibant la voie de PD-1 d'un anticorps anti-PD-1.
Patent CA-2941547-A1 (CA)
Title: Flash tank design
Inventor: JURETZEK UWE
IPC: F22B37/50
Filed: 2015-02-12
Abstract: The invention relates to a water-steam circuit (1) of a power plant (2), comprising at least one low-pressure steam system (3) and a reservoir (4) for waste water from the water-steam circuit (1), wherein the reservoir (4) has, in addition to at least one waste water feed line (31), a further heat supply (5) from the water-steam circuit (1) and a steam outlet (6) which is connected via a waste steam pipe (7) to the low-pressure steam system (3) of the water-steam circuit (1). The invention also relates to a method for cleaning waste water from a power plant (2) having a water-steam circuit (1), wherein the waste water is conducted into a reservoir (4) and, in addition to a steam fraction generated by automatic evaporation of waste water in the reservoir (4), a water fraction that is also produced is evaporated using energy from the water-steam circuit (1), and the entire steam mass flow is introduced into a low-pressure steam system (3) of the power plant (2).
Patent CA-2945302-A1 (CA)
Title: Defined composition gene modified t-cell products
Inventor: JENSEN MICHAEL C
IPC: A61K39/395
Filed: 2015-04-08
Abstract: Aspects of the invention described herein, concern approaches to make genetically modified T-cells comprising a chimeric antigen receptor for human therapy. In some alternatives, the methods utilize a selection and/or isolation of CD4+ and/or CD8+ T-cells from a mixed T-cell population, such as, peripheral blood or apheresis derived mononuclear cells. Once selected/isolated, the CD4+ and/or CD8+ T-cells are then activated, genetically modified, and propagated, preferably, in separate or isolated cultures in the presence of one or more cytokines, which support survival, engraftment and/or proliferation of the cells, as well as, preferably promoting or inducing the retention of cell surface receptors, such as CD62L, CD28, and/or CD27. Included herein are also methods of treatment, inhibition, amelioration, or elimination of a cancer by administering to a subject in need thereof, one or more types of the genetically engineered T-cells or compositions that comprise the genetically engineered T-cell prepared as described herein.
Patent CA-2945322-A1 (CA)
Inventor: ALI MAHFUZA B
IPC: C09D7/46
Filed: 2015-04-10
Abstract: An adhesion promoter coating composition includes an oligomeric alkylalkoxysiloxane and a compound comprising an electrophile moiety and an alkoxysilyl moiety. The electrophile moiety may contain a sulfide functional group, for example. A dust suppression coating composition includes an acrylic polymer comprising a quaternary ammonium moiety; and an oligomeric alkylalkoxysiloxane. The coating composition may further include a zirconium salt. The coating composition may be applied to roofing granules, and/or asphaltic compositions, among other things.
Patent CA-2947658-A1 (CA)
Title: Polymethine compounds and their use as fluorescent labels
Inventor: ROMANOV NIKOLAI NIKOLAEVICH
IPC: C09B23/02
Filed: 2015-05-07
Abstract: The present disclosure relates to compounds of formula (I) and their use as fluorescent labels. The compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.
Patent CA-2950542-A1 (CA)
Inventor: FARRELL ALICE
IPC: F16M11/18
Filed: 2016-12-05
Abstract: The invention relates to a monitor stand. Preferred embodiments are suited to providing height adjustment of a video screen above a work surface. The stand has an outer rod 2 and an inner rod 3. A handle 4 can be moved up and down within the outer rod 2 to move the inner rod 3 in corresponding fashion. The inner rod 3 can be locked at a selection of heights by turning a clasp 8 of the handle into one or other of a series of slots 6 in the outer pole. A connector 5 adapted to receive a video screen is secured to the inner pole so as to be height adjustable with the inner pole 3.
Patent CA-2950599-A1 (CA)
Title: Methods and apparatus for elastic deactivation in a laminate
Inventor: FERGUSON RYAN
IPC: B26D1/00
Filed: 2015-06-11
Abstract: A variable interference anvil and knife combination is provided to selectively sever elastics in a laminate and preferably not sever the nonwoven portions of the laminate. The distance between the anvil and the knife can be programmatically altered to provide for smaller or larger gaps as processing speeds are changed.
Patent CA-2951822-A1 (CA)
Inventor: WIELAND MANFRED
IPC: A61B17/86
Filed: 2015-07-03
Abstract: An end cap is provided comprising a head with a tool engagement portion and a shaft with a tip, wherein the shaft comprises a threaded conical portion starting from the tip and extending in a direction to the head. The thread may be provided with a constant pitch, i.e. with a constant distance between the turns of the thread.
Patent CA-2953354-A1 (CA)
Inventor: KEESE FRANK M
IPC: C08L27/12
Filed: 2009-12-18
Abstract: A coated fabric includes a reinforcement, a first coating disposed on the reinforcement, and a second coating disposed on the first coating. The first coating includes perfluoropolymer. The second coating includes perfluoropolymer and a silicone polymer in an amount in a range of 2wt% to 30wt%.
Patent CA-2957952-A1 (CA)
Inventor: THRELKELD KEVIN CHRIS
IPC: A01H5/10
Filed: 2017-02-15
Abstract: The present invention is in the field of soybean variety CL1463369 breeding and development. The present invention particularly relates to the soybean variety CL1463369 and its seed, cells, germplasm, plant parts, and progeny, and methods of using CL1463369 in a breeding program. The invention also relates to uses of soybean variety CL1463369.
Patent CA-2960763-A1 (CA)
Inventor: OKAMOTO HARUKA
IPC: A61P3/10
Filed: 2015-09-15
Abstract: The present invention provides antibodies that bind to glucagon and methods of using the same. According to certain embodiments, the antibodies of the invention bind human GCG with high affinity. The antibodies of the invention may be fully human antibodies. The antibodies of the invention are useful for the treatment of various diseases or disorders characterized by elevated blood glucose levels, as well as other GCG-related disorders.
Patent CA-2963427-A1 (CA)
Title: Gho/sec24b2 and sec24b1 nucleic acid molecules to control coleopteran and hemipteran pests
Inventor: NARVA KENNETH E
IPC: C12N15/113
Filed: 2015-10-08
Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of insect pests through RNA interference mediated inhibition of target coding and transcribed non coding sequences in insect pests, including coleopteran and/or hemipteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of insect pests, and the plant cells and plants obtained thereby.
Patent CA-2966679-A1 (CA)
Inventor: MATHEISL MICHAEL
IPC: G07C5/08
Filed: 2015-11-03
Abstract: The invention relates to a transport-monitoring module (2) which is arranged on a transport unit (3, 3', 3") in order to monitor a transport of the transport unit (3, 3', 3") of a person-transporting device (4). The transport-monitoring module (2) has a sensor (5) and localization apparatus (6, 7). A connection to a data memory (17) of the device (4) is established during the transport by means of an interface unit (9). The interface unit (9) is designed in such a way that transport monitoring data to be stored, which are based on sensor data of the sensor (5) and on localization data of the localization apparatuses (6, 7), can be permanently stored in the data memory (17) of the device (4). The design of the transport-monitoring module (2) is thereby simplified such that the transport-monitoring module is no longer a worthwhile item to be stolen. In addition, reliable access to the stored transport monitoring data is ensured beyond the end of the transport.
Patent CA-2969974-A1 (CA)
Title: Small molecule inhibitors of egfr and pi3k
Inventor: WHITEHEAD CHRISTOPHER EMIL
IPC: A61K31/517
Filed: 2015-12-15
Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazoline structure or a quinoline structure which function as dual inhibitors of EGFR proteins and PI3K proteins, and their use as therapeutics for the treatment of cancer and other diseases.
Patent CA-2970857-A1 (CA)
Title: Molecules d'anticorps anti-cxcl12 et leurs utilisations
Inventor: BALKWILL FRANCES ROSEMARY
IPC: C07K16/24
Filed: 2015-12-11
Abstract: L'invention concerne des molécules d'anticorps anti-CXCL12 et leurs utilisations, et en particulier des molécules d'anticorps anti-CXCL12 qui sont capables d'inhiber une activité biologique de CXCL12 in vitro et in vivo et leur utilisation pour le traitement de maladie médiée par CXCL12.
Patent CA-2971122-A1 (CA)
Inventor: YU HUA
IPC: C09B67/46
Filed: 2015-12-17
Abstract: A dispersant is provided comprising a blend of mono- and di-phosphate esters, each phosphate group being substituted with either one or two alkyl or alkenyl alkoxylate groups wherein the alkyl or alkenyl portion is a branched alkyl or alkenyl radical comprising 1-30 carbon atoms, the alkoxylate portion comprises ethoxylate monomers and/or propoxylate monomers, and the dispersant further comprises a basic component selected from an amidopropyldimethylamine, a heterocyclic amine, an ammonium ion, and an alkali metal ion. The dispersant is suitable for dispersing a variety of pigments and other particulate matter in either aqueous or organic media.
Patent CA-2971966-A1 (CA)
Inventor: HILL MARK
IPC: B65D65/02
Filed: 2015-11-18
Abstract: Package comprising a container (10, 110) and a wrapper (20, 120) of flexible multi-layer laminate sheet material surrounding the container. The wrapper comprises a first layer and a second layer outside the first layer. A first cut line in the first layer defines a first region of the first layer which overlies a lid (12, 112) of the container (10, 110). A second cut line in the second layer is offset from the first cut line. The second cut line defines a second region of the second layer. The second region overlies the lid and includes a peripheral portion (21, 121) where the second layer extends beyond the lid (12, 112). The peripheral portion (21, 121) of the second layer is separable from the first layer, can be used to lift the lid (12, 112) into the open position, and can be resealed against the first layer.
Patent CA-2973143-A1 (CA)
Title: Aerosol-generating article with integral heating element
Inventor: RUSCIO DANI
IPC: A24F40/40
Filed: 2016-01-22
Abstract: There is provided an aerosol-generating article (10) comprising a tobacco plug (12), a mouthpiece (18) positioned downstream of the tobacco plug (12), and a resistive heating element (22) positioned within the tobacco plug (12). The resistive heating element (22) comprises an upstream portion protruding from an upstream end of the tobacco plug (12), wherein the upstream portion of the resistive heating element (22) comprises at least two heater electrical contacts (30) for receiving a supply of electrical energy from at least two device electrical contacts when the aerosol-generating article (10) comprising the resistive heating element (22) is inserted into an aerosol-generating device (50).
Patent CA-2973301-A1 (CA)
Inventor: GUPTA MANISH KUMAR
IPC: A61P31/06
Filed: 2016-01-26
Abstract: La présente invention concerne des compositions dispersibles comprenant du fumarate de bédaquiline comme principe actif. Ces compositions s'avèrent utiles dans le traitement de la tuberculose et leurs propriétés inhérentes de dispersibilité les rend utiles notamment auprès de la population pédiatrique ou gériatrique.
Patent CA-2974329-A1 (CA)
Title: Metal-glycoprotein complexes and their use as chemotherapeutic compounds
Inventor: MANDEL ARKADY
IPC: A61K31/498
Filed: 2016-01-19
Abstract: Compositions of the invention include glycoproteins, such as transferrin, and metal-based coordination complexes, which are preferably chemotherapeutic compounds and more preferably tunable photodynamic compounds. The compositions are useful as in vivo diagnostic agents, and as therapeutic agents for treating or preventing diseases including those that involve hyperproliferating cells in their etiology, such as cancer. Compositions of the invention are further capable of destroying microbial cells, such as bacteria, fungi, and protozoa, and destroying viruses.
Patent CA-2974886-A1 (CA)
Inventor: LELEU MARTINE
IPC: A23L29/262
Filed: 2016-03-23
Abstract: The present invention relates to particles which comprise at least one gelled network of at least one gelling polysaccharide in which are embedded at least: - one caviar-based foodstuff; - one strengthening agent for the gelled network of gelling polysaccharide and which is resistant to alcohol; - and water, preferably purified water. The present invention also relates to an alcoholic beverage (for example a vodka) containing said particles, as well as a container filled with said alcoholic beverage.