baber/WOPTO huggingface dataset:
Patent IL-145303-A0 (IL)
Title: Pyridine and pyrimidine derivatives and their use as inhibitors of cytokine mediated disease
IPC: A61P11/06
Filed: 2000-03-17
Abstract: This invention concerns a bicyclic compound of Formula (I), wherein: G is N, CH or C(CN); ring X is a 5- or 6-membered fused heteroaryl ring which contains 1, 2, or 3 heteroatoms selected from oxygen, sulphur and nitrogen; m is 0-2; R<1 >is a group such as hydroxy, halo, trifluoromethyl, cyano, mercapto, nitro, amino, carboxy and carbamoyl; each of R<2 >and R<3 >is hydrogen, halo, C1-6alkyl, C2-6alkenyl or C2-6 alkynyl; R<4 >is a group such as hydrogen, hydroxy, C1-6alkyl, C1-6alkoxy, amino and N-C1-6alkylamino; R<5 >is a group such as hydrogen, halo, trifluoromethyl, cyano, nitro, amino and hydroxy, and q is 0-4; or a pharmaceutically acceptable salt or an in vivo cleavable ester thereof; processes for its preparation, a pharmaceutical composition containing it and its use in the treatment of diseases or medical conditions mediated by cytokines.
Patent IL-153733-A0 (IL)
Title: A new use for deferiprone
IPC: A61P9/00
Filed: 2001-06-28
Abstract: A method of treating iron induced cardiac disease in a patient with iron overload, such as in thalassemia or the like comprising administering to the patient a therapeutically effective amount of deferiprone or a physiologically acceptable salt thereof sufficient to treat induced cardiac disease normally associated with iron overload.
Patent IL-164256-A0 (IL)
Title: Combined dna/protein compositions
IPC: A61K39/39
Filed: 2003-03-28
Abstract: The present invention relates to a combined DNA/Protein antigen vaccine composition which includes nucleic acid molecules and a mineral-based, negatively charged adjuvant, so as to enhance the immunogenicity of the DNA vaccine efficiently, enhancing not only plasmid DNA vaccines but also providing a novel strategy for immunogenic, multivalent combined protein/DNA vaccine delivery. Preferred adjuvants are aluminum or calcium salts, in particular aluminum phosphate.
Patent IL-165327-A0 (IL)
Title: Low acceleration sensitivity mounting structures for crystal resonators
IPC: G01P15/09
Filed: 2004-11-22
Abstract: The invention is a method and apparatus for improving the aging, pressure sensitivity, and acceleration sensitivity of crystal resonators. In one embodiment the invention includes a coplanar two-dimensional compliant mounting structure, wherein the symmetry and compliance of the planar mounting structure reduces the effects of residual static stresses and dynamic vibratory stresses on the vibration sensitivity performance of a crystal resonator. The structural elements include compliance loops that provide relief from the effects associated with manufacturing, thermal and vibration stresses.
Patent IL-176035-A0 (IL)
Title: Machine for the continuous production of welded wire mesh
IPC: B21F1/00
Filed: 2006-05-31
Abstract: The invention relates to a machine for the production of a continuous strip of wire mesh (100) using a single flexible metal wire (20) which is fed to the machine continuously. According to the invention, the mesh (100) is formed by repeating the same pattern with the metal wire in one plane, each pattern being stacked on the preceding pattern with a constant pitch offset in the axial direction of production. The inventive machine comprises: a metal wire storage stage; a stage for continuously supplying metal wire to the machine; a forming stage for shaping the wire into a succession of identical patterns; a transfer stage for successively moving said metal wire patterns to the mesh-forming plane; a stage for maintaining each pattern in one plane and for offsetting same by a constant pitch with the arrival of the following pattern; and a stage for fixing the patterns to one another. The invention also relates to the strip of mesh (100) thus formed and to the production method thereof.
Patent IL-179286-A0 (IL)
Title: High solids fabric crepe process for producing absorbent sheet with in-fabric drying
IPC: D21H27/00
Filed: 2006-11-14
Abstract: A method of making a fabric-creped absorbent cellulosic sheet is provided which includes dewatering a papermaking furnish and partially drying the web without wet-pressing before applying it to a translating transfer surface moving at a first speed. The process further includes fabric-creping the web from the transfer surface at a consistency of from about 30 to about 60 percent utilizing a creping fabric, the creping step occurring under pressure in a creping nip defined between the transfer surface and the creping fabric wherein the fabric is traveling at a second speed slower than the speed of said transfer surface, the fabric pattern, nip parameters, velocity delta and web consistency being selected such that the web is creped from the surface and redistributed on the creping fabric. After creping, the web is dried, preferably with a plurality of can dryers to a consistency of at least about 90 percent while it is held in the creping fabric.
Patent IL-180972-A0 (IL)
Title: 5-beta-sapogenin and psuedosapogenin derivatives and their use in the treatment of dementia
IPC: A61P43/00
Filed: 2007-01-25
Abstract: The invention discloses the use of sapogenin derivatives in the treatment of cognitive dysfunction and similar conditions. Methods of treatment and pharmaceutical compositions are also disclosed.
Patent IL-182613-A0 (IL)
Title: Dial-down mechanism for wind-up pen
Filed: 2007-04-17
Abstract: The present invention relates to a dial-down mechanism for an injection device comprising a torsion spring for assisting injection of a dose of medicament from the injection device, the dial-down mechanism comprising dial-up cam arranged to receive and engage with a dial-up key, wherein the dial-up cam and the dial-up key are adapted to, upon rotation of a dose setting member in a first direction, cooperate to strain the torsion spring of the injection device, and a dial-down cam arranged to receive and engage with a dial-down key, wherein the dial-down cam and the dial-down key are adapted to, upon rotation of the dose setting member in a second direction, cooperate to release the torsion spring of the injection device, the second rotation direction being opposite to the first rotation direction.
Patent RO-126606-A0 (RO)
Title: Analytical () method for identifying, dosing fluorfenicol and the chemically related impurities in the pharmaceutical products fluorfenidem 10%-oral solution, fluorfenidem 50 and fluorfenicol asactive pharmaceutical ingredient
Inventor: NEAGU MARIA
IPC: G01N30/02
Filed: 2010-08-31
Abstract: The invention relates to an analytical method for identifying and dosing florfenicol and the related chemical impurities in the pharmaceutical products containing this active ingredient. According to the invention, the method comprises a HPLC chromatography by using a octadecylsillyl silicagel for R chromatography, with the length of 150 mm, the inside diameter of 4.6 mm, particle size of 5 μ m, at a column temperature of 25°C, with isocratic eluation, the composition of the movable phase being Solvent A: Solvent B 60:40 v/v, where the Solvent A is HPLC water and Solvent B is acetonitrile R, with a flow rate of the movable phase of 1ml/minute, with UV detection at the length of 254 nm, column in which there are injected 10 μ m of reference solution a, containing 5000 ppm of florfenicol, this solution also representing the solution for testing the chromatographic system, on the condition of the existence of at least 500 theoretical plates for the peak of florfenicol.
Patent RO-134368-A0 (RO)
Title: Progressive gambling game
Inventor: SIMCELESCU NICOLAE DANIEL
IPC: A63F3/08
Filed: 2020-02-07
Abstract: The invention relates to a progressive poker game, which can be played either in casinos or poker clubs, or as a private group game. According to the invention, the game consists of an oval table (1), around which two to six players (P1 ... P6) may be seated, a croupier (C), a dealer button chip (D), which represents the point of starting the dealing of cards and a chip holder (S); on the table (1), in front of each player (P1 ... P6) there are marked 13 individual game boxes (CB1 ... CB5, CM1 ... CM5, CT1 ...CT3), arranged on three lines (LB, LM and LT) of base, middle and top boxes.
Patent ES-442775-A1 (ES)
Title: Control devices for reversible flow variable capacity hydraulic machines
IPC: F04B1/26
Filed: 1975-11-18
Abstract: A signal is transmitted from a oscillatable piston to a valve by a mechanism comprising a first link pivotal about a second axis and a second link pivotal about a third axis which is perpendicular to the second axis. The second link abuts the first link on both sides of the second axis to transmit motion from the first link to the valve.
Patent MA-20479-A1 (MA)
IPC: B01D33/04
Filed: 1985-07-02
Abstract: Belt filter device comprising a frame (7), an endless conveyor belt (1) guided along drums (2, 3) and at least one casing (4) arranged below the upper run of the belt, in which subatmospheric pressure can be created for sucking fluid from material lying on the conveyor belt during operation through holes provided for this purpose in the conveyor belt (1), said casing (4) being pivotable with respect to the frame between a first position suitable for operation in which a cover of the casing having at least one passage for the fluid is in contact with the bottom side of the upper run of the conveyor belt and a cleaning position in which the casing is turned downwards in a direction away from the upper run of the conveyor belt, said casing being pivotable with respect to the cover.
Patent MA-23064-A1 (MA)
Inventor: KAREN KACZMAREK LEEKER
IPC: A61F13/551
Filed: 1993-12-21
Abstract: An improved fold and wrap package providing containment of a catamenial pad prior to its use and for conveniently disposing of a soiled catamenial pad. The fold and wrap package comprises a wrapper comprising a single strip of material having a flap panel, a central panel, and an end panel; and preferably a tape tab for securing the wrapper in a disposal configuration to provide convenient disposal of a soiled catamenial pad wrapped in the wrapper. The fold and wrap package is initially configured to have a pouch and a flap. The pouch is formed by folding the end panel back upon the central panel and frangibly bonding the end panel to the central panel at the longitudinal edges so that the end panel may be easily peeled away from the central panel to provide convenient disposal of a soiled catamenial pad. The pouch is designed so that an unused catamenial pad may be disposed within the pouch with the flap being positioned over the mouth of the pouch and frangibly bonded to the pouch to securely close the pouch prior to use. The fold and wrap package is used by peeling the tape tab from the pouch, peeling the flap away from the pouch by breaking the frangible bonds between the flap and the pouch, removing the unused catamenial pad from the pouch, peeling the end panel from the central panel to open the pouch such that the fold and wrap package is a flat wrapper (these previous two steps may also be done in reverse order), securing a soiled catamenial pad to the wrapper, disposing the wrapper and the soiled catamenial pad into a disposal configuration, and securing the wrapper and the soiled catamenial pad in its disposal configuration by securing the tape tab to another portion of the wrapper. <IMAGE>
Patent MA-23466-A1 (MA)
Inventor: LUCIEN Y BRONICKI
IPC: F02C1/04
Filed: 1995-02-28
Abstract: An externally fired gas turbine system has a compressor for compressing ambient air and producing compressed air, an indirect-contact air heat exchanger for heating the compressed air to produce heated compressed air, an air turbine for expanding the heated and compressed air to produce expanded air, and a generator connected to the turbine for generating electricity that is supplied to a load. The system also includes a source of energy including solar energy, oil shale, solid waste fuel, land fill gas, biomass, or combinations thereof, and/or solid, liquid, or gaseous hydrocarbon fuels, for adding heat to the compressed air in the air heat exchanger and producing heat depleted gases that exit the air heat exchanger. Also provided is a closed Rankine cycle power plant having a water heat exchanger for vaporizing water and producing steam using heat contained in the heat depleted gases, a steam turbine for expanding the steam and producing power for the load, and expanded steam, a steam condenser for condensing the expanded steam and producing condensate, and means for returning said condensate to the water heat exchanger.
Patent MA-27888-A1 (MA)
Inventor: FRYSZMAN OLGA M
IPC: C07D413/12
Filed: 2005-12-21
Abstract: Provided are 5-membered heterocycle-based p38 kinase inhibitors. Further provided are pyrazole and imidazole-based p38 kinase, including p38± and p38² kinase, inhibitors. Pharmaceutical composititons coataining the compounds are also provided. Methods of use of the compounds and compositions are also provided, including methods of treatment, prevention, or amelioration of one or more symptoms of p38 Kinase mediated diseases and disorders, including, but not limited to, inflammatory diseases and disorders.
Patent MA-40657-A1 (MA)
Title: Composition pharmaceutique stable comprenant du pemetrexed ou un sel pharmaceutiquement acceptable de celui-ci
Inventor: SOHN MI-WON
IPC: A61K47/18
Filed: 2015-11-06
Abstract: La présente invention concerne une composition d'une solution injectable prête à l'emploi comprenant du pemetrexed ou des sels pharmaceutiquement acceptables de ceux-ci, comprenant : du pemetrexed ; du sulfite de sodium anhydre ; et de la n-acétyl-l-cystéine. Relativement à une utilisation en tant que préparation injectable, la composition d'une solution injectable prête à l'emploi comprenant le pemetrexed de la présente invention est appropriée pour une administration efficace de pemetrexed étant donné q
Patent MA-41525-A1 (MA)
Title: Appareil de mesure de niveau de remplissage, procédé pour faire fonctionner un appareil de mesure de niveau de remplissage et module comprenant un appareil de mesure de niveau de remplissage et au moins un élément d'écartement
Inventor: MERKER JOHANNES
IPC: G01F23/296
Filed: 2016-08-19
Abstract: L'invention concerne un appareil de mesure de niveau de remplissage (10) pour mesurer le niveau de remplissage dans un réservoir (2) à travers sa paroi (9) par ultrasons, l'appareil comprenant une tête de mesure ultrasonore (12), une commande (20) et un dispositif de fixation (24) au moyen duquel l'appareil de mesure de niveau de remplissage (10) peut être fixé au réservoir (2) de sorte que la tête de mesure ultrasonore (12) appuie contre la paroi (9) du réservoir (2). L'invention concerne par ailleurs un procédé pour faire fonctionner un tel appareil de mesure de niveau de remplissage (10), une vitesse d'échantillonnage qui dépend de la situation, étant employée. L'invention concerne finalement un module comprenant un tel appareil de mesure de niveau de remplissage et au moins un élément d'écartement (50) qui peut être mis en place sur le bord inférieur d'un réservoir (2) devant être équipé de l'appareil de mesure de niveau de remplissage (10).
Patent MA-49803-A1 (MA)
Title: Désinfecteur de chaussures par pulverisation automatique
Inventor: TOUMI JILALI
IPC: A61L2/24
Filed: 2020-05-15
Abstract: Désinfecteur de chaussures objet de l’invention est un dispositif permettant la décontamination des chaussures par pulvérisation du décontaminant en posant le(s) pied(s) sur un support sous lequel sont montées des buses de pulvérisation alimentées par pompe haute pression,désinfecteur de chaussures simple ou double prêt à être installé dans les gares, les aéroports, à l'entrée d'habitations, de bureaux, de magasins et autres, pour faire face aux défis de la pandémie due au covid-19
Patent MA-53772-A1 (MA)
Title: Lieurs sans trace et conjugués protéiques associés
Inventor: HAN AMY
IPC: C07J41/00
Filed: 2020-01-08
Abstract: L'invention concerne des composés, des composés comprenant des lieurs sans trace, des conjugués protéiques associés, et des compositions associées. L'invention concerne également des méthodes de traitement de maladies, de troubles et d'états, et/ou la gestion de leurs symptômes, associés à des maladies inflammatoires et des troubles auto-immuns associés en outre au récepteur des glucocorticoïdes, à la liaison aux glucocorticoïdes et/ou à la signalisation des récepteurs des glucocorticoïdes, comprenant l'administration des composés ou de charges utiles par l'intermédiaire de charges utiles de lieurs sans trace, et des conjugués protéiques associés.
Patent UY-25300-A1 (UY)
Title: Composiciones conteniendo un antagonista alfa adrenérgico y un compuesto que eleva los niveles de cgmp para el tratamiento de la impotencia
Inventor: WYLLIE MICHAEL GRANT
IPC: A61K31/535
Filed: 1998-12-14
Abstract: Esta invención se refiere al tratamiento de la disfunción eréctil con una combinación de un compuesto seleccionado entre antagonistas de los receptores a-adrenergicos, y un compuesto seleccionado entre los agentes que elevan los niveles de cgmp. se prefiere como elevador de cgmp pde al sildenafilo o una sal farmacéuticamente aceptable del mismo. También se incluyen composiciones y estuches que comprenden tales compuestos para el tratamiento de la impotencia.
Patent UY-25969-A1 (UY)
Title: Proceso mejorado para la preparación de conjugados de polimixina b/dextrano
Inventor: KAPA PRASAD
Filed: 2000-01-17
Abstract: El proceso mejorado para producir conjugados de polimixina B (PMB) y dextrano, solubles en agua, que consiste en hacer reaccionar polimixina B o una sal de la misma farmacéuticamente aceptable, con dextrano, en un medio acuoso, a un pH de aproximadamente 9,5 a 10, y a una temperatura de aproximadamente 32sC. Una variante preferida del proceso involucra hacer reaccionar sulfato de polimixina B con dextrano oxidado para unir covalentemente la mólecula de PMB al dextrano, a través de un enlace amina. Los conjugados tienen una actividad antiendotoxinas mayor que la PMB no conjugada. Dichos compuestos presentan actividad antibacteriana y también son útiles para combatir infecciones fúngicas.
Patent UY-28225-A1 (UY)
Title: Derivados azabiciclicos de piridiloximetilo y bencisoxazol
Inventor: BRIGHT GENE MICHAEL
IPC: C07D487/04
Filed: 2004-03-11
Abstract: Un compuesto azabicílico sustituido de aminometilpiridiloximetilo/bencisoxazol, una composición farmacéutica que comprende el mismo y un método para tratar uno o mástrastornos del CNS u otros, que incluye el tratamiento concurrente de trastornos como esquizofrenia y depresión.
Patent UY-29472-A1 (UY)
Title: Metodos para el tratamiento del dolor por osteoartritis mediante la administracion de un antagonista del factor de crecimiento de los nervios y composiciones que lo contienen
Inventor: SHELTON DAVID L
Filed: 2006-04-11
Abstract: La invención se refiere a anticuerpos anti-NGF (tal como anticuerpos antagonistas anti-NGF), y polinucleótidos que codifican los mismos. La invención adicionalmente se refiere al uso de tales anticuerpos y/o polinucleótidos en el tratamiento y/o prevención de dolor, incluyendo dolor post-quirúrugico, dolor por artritis reumatoide, y el dolor por osteoartritis.
Patent UY-30524-A1 (UY)
Title: Anticuerpos dirigidos a avb(beta)6 y sus usos
Inventor: BARRY SIMON THOMAS
IPC: C12N5/10
Filed: 2007-08-03
Abstract: Se describen agentes de union dirigidos, anticuerpos de este tipo dirigidos al antígeno a(alfa) VB(Beta)6 y usos de dichos agentes. En particular, se describen anticuerpos monoclonales completamente humanos dirigidos al antígeno a(alfa)VB(Beta)6. Se describen secuencias de nucleotidos que codifican, y secuencias de aminoácios que comprenden, moléculas de inmunoglobulina de cadena pesada y liviana, en particular secuencias que se corresponden con secuencias contiguas de cadena pesada y liviana que abarcan las regiones estructurales (FR) y/o las regiones determinantes de la complementariedad (CDR), específicamente desde la FR1 hasta la FR4 inclusive, o desde la CDR1 hasta la CDR3 inclusive. Se describen asimismo hibridomas u otras íneas celulares que expresan dichas moléculas de inmunoglobulina y dichos anticuerpos monoclonales.
Patent CH-718288-A1 (CH)
Title: Dispositif de prise de son pour instrument à cordes.
Inventor: FRÉDÉRIC NICOLET
IPC: G10H3/18
Filed: 2021-01-29
Abstract: La présente invention concerne un dispositif de prise de son pour un instrument à cordes (1) comportant une pièce (2), aussi appelée pontet, munie d'un transducteur (6) disposé au sein de la pièce (2), ladite pièce (2) étant formée d'une première face opposée à une seconde face , lesdites première et seconde faces étant reliées par une paroi, ladite paroi présentant sur une portion une découpe destinée à former une zone d'appui pour la corde (5), ladite seconde face comportant un ergot (3) destiné à se loger dans un châssis de l'instrument à cordes (1) pour assurer son maintien en position. La présente invention concerne également un instrument à cordes comportant un dispositif de prise de son à la base de chaque corde,
Patent ES-171053-A1 (ES)
Title: UN PROCEDIMIENTO PARA LA FABRICACIoN DE ABONOS DE ACCIoN LENTA A BASE DE FOSFATO CáLCICO
Filed: 1945-09-22
Abstract: Procedimiento para la fabricación de abonos de acción lenta a base de fosfato cálcico caracterizándose porque el P2O5 resulta lentamente disponible y porque primero aplicado al suelo tiene una solubilidad relativamente reducida en agua y ácido cítrico comprendiendo dicho procedimiento el calentamiento a auna temperatura superior a 250ºC. el modo de mezclar un material fosfático y una proporción de ácido sulfúrico que asciende desde 0 6 moléculas por cada molécula de P2O5 contenida junto con una cantidad adicional y suficiente para reaccionar con las impurezas presentes y porque se supone para los efectos del cálculo que el P2O5 está presente en el material fosfático en forma de Ca3(PO4)2.
Patent ES-181948-A1 (ES)
Title: UN PROCEDIMIENTO DE FABRICAR UNA PORCIoN DE UN COSTADO DE VEHiCULO
IPC: B61D17/08
Filed: 1948-01-30
Abstract: Un procedimiento de fabricar una porción de un costado de vehículo que comprende; colocar una chapa plana en una superficie de trabajo plana con la chapa cabalgando en una abertura entre dos porciones de la superficie de trabajo, colocar electrodos de soldadura encima y debajo de la chapa en la abertura entre las dos, porciones espaciadas de la superficie de trabajo, con el electrodo inferior espaciado ligeramente debajo del plano de la superficie de trabajo, colocar un reforzador en la cara superior de la chapa, de manera que el reforzador se extienda al través de la abertura de la superficie de trabajo, bajar el electrodo superior contra el reforzador y aplicar una fuerza para arquear la chapa y el reforzador hacia abajo dentro de sus límites elásticos hasta hacer contacto con el electrodo inferior, soldar el reforzador a la chapa mientras están en esta posición arqueada, y dejar luego que el panel y los reforzadores vuelvan aun estando virtualmente plano.
Patent ES-182203-A1 (ES)
Title: DSISTEMAS DE GENERACIoN DE IMPULSOS
Filed: 1948-02-09
Abstract: Sistema de generación de impulsos caracterizado por un método para producir un impulso de determinada duración comprendiendo la elevación de un potencial de impulsos, e iniciando la elevación de un potencial de control, y utilizando dicho potencial de control, y utilizando dicho potencial de control para llevar el shunt de la fuente de potencial del impulso a un intervalo escogido después de la iniciación de manera a producir una caída de potencial que determine un borde de cola para el impulso.
Patent ES-182587-A1 (ES)
Title: UN SISTEMA FOTOELÉCTRICO DE LECTURA DIRECTA PARA LA MEDICIoN DE EVALUACIONES CROMáTICAS DE MATERIAS
Filed: 1948-02-23
Abstract: Un sistema fotoeléctrico de lectura directa para la medición de evaluaciones cromáticas de materias, caracterizado por el hecho de operar en condiciones de luz siempre de igual intensidad, mediante una cédula fotoeléctrica, disponiendo el líquido o medio a examinar, sea turbio,opalescente o colorado, entre un manantial luminoso y el foto-elemento, de tal manera que dicho líquido, o medio se halla alojado en un cilindro de vidrio amovible,deslizante en alojamiento adecuado.