baber/WOPTO huggingface dataset:
Patent DK-2822968-T3 (DK)
Inventor: KWAKS THEODORUS HENDRIKUS JACOBUS
IPC: C07K16/10
Filed: 2013-03-07
Granted: 2018-04-16
Abstract: Described are binding molecules, such as human monoclonal antibodies, that bind to hemagglutinin of influenza B viruses, and have a broad neutralizing activity against such influenza viruses. These binding molecules do not bind to hemagglutinin of influenza A viruses. Further provided are nucleic acid molecules encoding the binding molecules, and compositions comprising the binding molecules. The binding molecules can be used in the diagnosis of, prophylaxis against, and/or treatment of influenza B virus infections.
Patent DK-3086797-T3 (DK)
Inventor: HENDRIKS MAIKEL
IPC: A61P31/12
Filed: 2013-12-23
Granted: 2018-08-20
Abstract: The invention provides a dermatological composition comprising materials of algae origin (e.g. Arthrospira platensis) and olive leaf origin, the composition at least comprising a polypeptide and hydroxytyrosol. The composition is for use in the treatment and/or prevention of a dermatological microbial infection, e.g. nail fungus, Athlete's foot, wound, chickenpox, acne. The invention also provides an applicator device comprising such composition. Further, the invention provides a method for preparing such dermatological composition. Especially, the composition at least comprises a polypetide and hydroxytyrosol.
Patent DK-2934598-T3 (DK)
Inventor: CHEN ZHIJIAN
IPC: A61P37/00
Filed: 2013-12-16
Granted: 2018-07-23
Abstract: Cyclic-GMP-AMP synthase (cGAS) and cyclic-GMP-AMP (cGAMP), including 2′3-cGAMP, 2′2-cGAMP, 3′2′-cGAMP and 3′3′-GAMP, are used in pharmaceutical formulations (including vaccine adjuvants), drug screens, therapies and diagnostics.
Patent DK-3109063-T3 (DK)
Inventor: ZANGHELLI PATRICK
IPC: B61F19/04
Filed: 2016-06-21
Granted: 2018-05-22
Abstract: The invention relates to a wheel axle for a vehicle, the wheel axle comprising a shaft extending along a main axis, a first protection device and at least one second protection device, each device comprising a body at least partially surrounding the shaft in a plane perpendicular to the main axis, the body having a first end portion and a second end portion, the end portions being opposite one another along their main axis. The first end portion of the first device at least partially surrounds the second end portion of the second device in a plane perpendicular to the main axis.
Patent DK-3139042-T3 (DK)
Inventor: ARGENTINO PIERLUIGI
IPC: F04D13/02
Filed: 2016-08-11
Granted: 2018-07-30
Abstract: A mechanical coupling group of two devices (2, 3), respectively provided with a drive shaft (4) and a driven shaft, is constituted by a coupling body (1) having a hollow cylindrical central portion able to contain coupled ends of the two shafts, and two end flanges (12, 13) of which a first flange (12) destined to couple with the body of the device provided with the driven shaft, and a second flange (13) destined to couple with the body of the device provided with the drive shaft (4), threaded fixing means (33, 122) being provided with a broadened head (331) for fixing each of the two flanges (12, 13) to the body of the respective device, in which the second flange (13) destined to couple with the body of the device provided with the drive shaft (4) comprises at least three first equidistant recesses (131) located on a circumference thereof, and having a larger diameter than a diameter of the broadened head (331) of the threaded fixing means (33) of the flange, a cylindrical tract branching from each first recess (131) having a diameter that is identical to a diameter of the circumference on which the threaded means (33) reduced by a half of the diameter thereof are located, which cylindrical portion terminates in a second recess (133) facing towards the first recess (131) and having a smaller diameter than the broadened head (331) of the threaded means (33).
Patent DK-0387712-T3 (DK)
Inventor: HATANAKA HIROSHI
IPC: A61K35/74
Filed: 1990-03-09
Granted: 1995-08-14
Abstract: A biologically pure culture of Streptomyces resistomycificus No. 7622 (FERM BP-2306), new compounds WS7622A, B, C and D obtainable by culturing Streptomyces resistomycificus No. 7622 in a nutrient medium and isolating them or their pharmaceutically acceptable salts, and derivatives of such new compounds, and pharmaceutical compositions comprising such new compounds or their pharmaceutically acceptable salts as an active ingredient.
Patent DK-0391442-T3 (DK)
Inventor: YOSHITAKE NORIAKI
IPC: C23C22/26
Filed: 1990-04-06
Granted: 1993-12-20
Abstract: Zinciferous surfaces, particularly those of galvanized steel, may be effectively protected against corrosion, either as treated or after painting, while remaining easy to weld, by contact with an aqueous solution containing chromium in both +6 and +3 valence states, phosphate, a tertiary alcohol or similar oxidation stable, water soluble organic compound as a wetting agent, and a silane coupling agent, followed by drying with a film from the solution still in place on the surface. A thin coating containing 10 - 200 mg/m<2> of chromium is formed on the surface to provide a protective layer that is also an excellent base for paint.
Patent DK-0411534-T3 (DK)
Inventor: KESTER JEFFREY ALAN
IPC: A61P25/28
Filed: 1990-07-30
Granted: 1995-07-24
Abstract: Novel prodrugs or depot derivatives of 1,2,3,4-tetrahydro-9-acridinamine of formula I <CHEM> are described, as well as methods for the preparation and pharmaceutical compositions of same, which are useful as analgesic agents for the treatment of pain, as sleep aids and as agents for treating the symptoms of senile dementia, Alzheimer's disease, Huntington's chorea, tardive dyskinesia, hyperkinesia, mania, or similar conditions of cerebral insufficiency characterized by decreased cerebral acetylcholine production or release.
Patent DK-0413343-T3 (DK)
Inventor: SASHO SETSUYA
IPC: A61K31/415
Filed: 1990-08-16
Granted: 1995-12-11
Abstract: A furan derivative and a pharmaceutically acceptable salt thereof having gastrointestinal enterokinetic activity which is expected to be used in a broad spectrum of diseases associated with gastrointestinal dyskinesia.
Patent DK-0399748-T3 (DK)
Inventor: KELLY SARAH ELIZABETH
IPC: C07D209/58
Filed: 1990-05-21
Granted: 1996-02-12
Abstract: Preparation of 2-oxindole-1-carboxamides by reaction of 2-oxindoles with trichloracetyl isocyanate to produce novel N-trichloroacetyl-2-oxindole-1-carboxamides which are then hydrolyzed to 2-oxindole-1-carboxamides useful as analgesic and antiinflammatory agents and/or intermediates for such agents.
Patent DK-0427604-T3 (DK)
Inventor: ARNAUD DIDIER
IPC: C08J9/14
Filed: 1990-11-05
Granted: 1993-05-17
Abstract: An azeotrope of minimum boiling point, capable of being employed as refrigerating fluid replacing chlorofluorocarbons or as an extinguishing agent replacing bromofluorocarbons and chlorobromofluorocarbons. The azeotrope according to the invention is a mixture of 1,1,1,2-tetrafluoroethane and perfluoropropane. At normal boiling point (approximately -41.1 DEG C at 1.013 bar) its perfluoropropane content is approximately 76 mass% and that of 1,1,1,2-tetrafluoroethane is 24 %. This azeotrope can also be employed as an aerosol propellant or as a blowing agent for plastic foams.
Patent DK-0455735-T3 (DK)
Inventor: THIEME THOMAS
IPC: G01N33/58
Filed: 1990-01-25
Granted: 1994-12-12
Abstract: A method for detection for screening and diagnostic purposes of antibodies in a body fluid by means of an antibody-binding protein covalently bound to a porous matrix trapped within a transparent column. A test fluid containing antibody is contacted with the protein-bound matrix whereby the protein reacts with to immobilize any antibody present in the test fluid. A biotinylated antigen of interest is contacted with the immobilized antibody whereby the biotinylated antigen binds to the immobilized antibody. Avidin covalently linked to an enzyme is contacted with the immobilized biotinylated antigen-immobilized antibody-protein bound matrix complex whereby the enzyme-labelled avidin binds to the immobilized complex. This immobilized complex is contacted with a substrate solution wherein the enzyme linked to avidin catalyzes a reaction of the substrate and produces a detectable reaction product which correlates to the presence of the antibody to be detected.
Patent DK-0441467-T3 (DK)
Inventor: SCHWARZ KATICA
IPC: A61P35/00
Filed: 1991-02-06
Granted: 1994-10-03
Abstract: The description relates to novel side-chain-homologous vitamin D derivatives of formula (I), in which R<1>, R<2>, R<3>, R<4>, R<5> and R<6> have the significance given in the description, B and D are either a hydrogen atom or together a second bond (E-configuration double bond) and either A is a direct bond between the carbon atoms 20 and 22 and X is an alkyloxy radical -(CH2)nO- with n = 1 to 3 or A is a methylene bridge (-CH2-) between the carbon atoms 20 and 22 and X is an alkylene radical -(CH2)n- or an alkylenoxy radical -(CH2)nO- with n = 1 to 3, or if A is a direct bond and B and D together are a second bond, (a) is one of the radicals (b) , -(CH2)2-= or -(CH2)2-=, and a process for their production, pharmaceutical preparations containing this compound and its use in making medicaments. The new compounds have proliferation-inhibiting and cell-differentiating effects.
Patent DK-0442788-T3 (DK)
Inventor: CORDONNIER ALAIN
IPC: B07B7/00
Filed: 1991-02-08
Granted: 1995-02-20
Abstract: A pneumatic centrifugal separator comprises guide vanes disposed along the generatrices of a fictitious cylinder having a vertical axis, the guide vanes being adapted to impart to a gas stream entering the fictitious cylinder a rotary motion about the vertical cylinder axis, and a rotor coaxially positioned in the interior of the fictitious cylinder, the rotor being equipped with a first set of vertical blades distributed uniformly along the periphery of the fictitious cylinder and a second set of blades disposed between the blades of the first set and the cylinder axis. A gas stream and particulate material to be sorted is introduced between the guide vanes and the rotor, and the gas stream charged with particles of dimensions smaller than predetermined dimensions and sorted out of the particulate material is drawn out of a central outlet. The second set of blades is arranged to guide the streams of gas coming through channels between adjacent vertical blades of the first set to the central outlet.
Patent DK-0463947-T3 (DK)
Inventor: CERF MARTINE
IPC: C07C317/18
Filed: 1991-06-21
Granted: 1995-12-04
Abstract: Process for the preparation of a (meth)acrylate (VI) where G = -CH2SR' (R' = alkyl which may carry an OH functional group, in which case Q = alkyl, or else H); or G = H or CH3, in which case Q = -(CH2)n-SxOyZ (1 </= n </= 12; 1 </= x </= 3; 0 </= y </= 2; and Z = alkyl, cycloalkyl, alkenyl, aryl, alkylaryl, aralkyl or heterocyclic ring which may carry an ester functional group), by reaction of a (meth)acrylate (VII), where R = H, CH3 or -CH2X (X = Hal and Q = alkali metal or alkyl) with a sulphur compound R'SH or ZS(CH2)nX, the said reaction being carried out in an at least partially aqueous medium at 50-100 DEG C or in an organic solvent whose b.p. < 100 DEG C, in the presence of at least one polymerisation inhibitor and of at least one phase transfer agent and resulting, when R = H or CH3, in a (meth)acrylate (VI-a) where G = H or CH3 and y = 0, in which case this first reaction may be followed by an oxidation reaction at approximately 10-60 DEG C, to obtain a (meth)acrylate (VI) where y > 0. <IMAGE>
Patent DK-0531315-T3 (DK)
Inventor: WOELDIKE HELLE FABRICIUS
IPC: C12N1/19
Filed: 1991-05-08
Granted: 1997-09-22
Abstract: A cellulose- or hemicellulose-degrading enzyme which is derivable from a fungus other than Trichoderma or Phanerochaete, and which comprises a carbohydrate binding domain homologous to a terminal A region of Trichoderma reesei cellulases, which carbohydrate binding domain amino acid sequence ( alpha ) or a subsequence thereof capable of effecting binding of the enzyme to an insoluble cellulosic or hemicellulosic substrate.
Patent DK-0546102-T3 (DK)
Inventor: ITOH NORIIE
IPC: C07D213/74
Filed: 1991-08-27
Granted: 1998-06-02
Abstract: The present invention provides novel tropolone derivatives of the formula I   <IMAGE>   wherein R10 is a substituted or unsubstituted piperazinyl or benzothiazolidinyl group, and pharamaceutical compositions thereof. These compounds are useful for the prevention and treatment of ischemic diseases, including cerebrovascular diseases and cardiovascular diseases.
Patent DK-0512087-T3 (DK)
Inventor: AMBROSIUS DOROTHEA
IPC: C07K1/02
Filed: 1991-11-21
Granted: 1997-08-25
Abstract: PCT No. PCT/EP91/02190 Sec. 371 Date Jul. 2, 1992 Sec. 102(e) Date Jul. 2, 1992 PCT Filed Nov. 21, 1991 PCT Pub. No. WO92/09622 PCT Pub. Date Jun. 11, 1992The invention concerns a process for the reactivation of denatured protein, in which the protein is incubated with a solution of Tris base or/and a salt of Tris at a concentration of at least 400 mmol/l and at a pH at which the protein to be treated can take up its native conformation.
Patent DK-0521388-T3 (DK)
Inventor: TRITTHART WOLFRAM DR
IPC: A61K9/46
Filed: 1992-06-25
Granted: 1995-09-11
Abstract: An aqueous solution or dispersion for oral intake of at least two different pharmaceutical agents is prepared by dissolving or suspending at least two different effervescent, soluble and/or disintegrating mixtures in the form of tablets or granules, each of which contains a different agent or a different combination of agents, in one and the same amount of water. At least one of the tablets may be employed only as a fragment, and at least one of the mixtures may weigh less than 2000, preferably less than 1500, in particular less than 1000, mg. In particular, at least one of the mixtures contains a diuretic, especially hydrochlorothiazide and/or furosemide, and at least one of the other mixtures contains a beta blocker and/or a vasodilator, in particular naftidrofuryl, calcium antagonist, ACE inhibitor, alpha-1 blocker. Effervescent, soluble and/or disintegrating mixtures of this type in the form of tablets or granules are preferably used for the treatment of hypertension. Other combinations of agents are suitable for the treatment of asthma, osteoporosis or for ulcer therapy.
Patent DK-0552326-T3 (DK)
Inventor: VICTOR CARL-GUSTAV
IPC: B60C/
Filed: 1992-06-11
Granted: 1995-11-06
Abstract: An arrangement for retaining a tire on a vehicle wheel. The arrangement has a device for locking a tire against the wheel rim and pressing the tire beads against the rim flanges and rim seats. The device for locking the tire includes a plurality of clamping jaws disposed in spaced-apart relation to one another about the rim. Each jaw is rotatable about a clamping bolt. The rim of the wheel is provided, on its bottom, with fixing lugs. The jaws, when in an operative position, are applied against the fixing lugs to prevent the jaws from rotating about their clamping bolt.
Patent DK-0617602-T3 (DK)
Inventor: OSBORN THOMAS WARD
IPC: A61F13/49
Filed: 1992-11-06
Granted: 1997-04-21
Abstract: An absorbent article, such as a diaper, sanitary napkin, adult incontinent device, and the like having fused layers is provided. The absorbent article preferably comprises a liquid pervious thermoplastic apertured film topsheet, a liquid impervious backsheet, an absorbent core, and a fibrous acquisition web of spunlaced nonwoven fibers. The absorbent core is positioned between the topsheet and backsheet which are joined at least about a portion of the periphery of the absorbent article and the topsheet is fused to the acquisition web at discrete points of attachment. The acquisition web is positioned between the topsheet and the absorbent core.
Patent DK-0558897-T3 (DK)
Inventor: BUECHSENSCHUSS META
IPC: A43B17/02
Filed: 1993-01-18
Granted: 1996-02-26
Abstract: The subject of the invention is an insole which on its upper side has profilings for exerting a massage effect on the foot tissue. According to the invention, the profilings are designed as knobs (2a) and arranged in special regions (2) of the sole surface, these special regions being selected according to points of view of reflex-zone therapy for activating certain organs. <IMAGE>
Patent DK-0564770-T3 (DK)
Inventor: DUBOFF SHIRLEY ANN
IPC: A23L27/20
Filed: 1993-02-03
Granted: 1997-03-17
Abstract: A process for the preparation of diacetyl which comprises fermenting an aqueous pectin slurry with a lactic acid producing bacteria at a temperature from 16 DEG C to 38 DEG C, a pH of 4.0 to 7.0 for a period of from 8 to 24 hours under aerobic conditions.
Patent DK-0600544-T3 (DK)
Inventor: LEVY JOSEPH
IPC: A61P35/00
Filed: 1993-11-25
Granted: 2002-11-18
Abstract: A method of reducing the activity of a cell comprises administering to the cell of a subject in need thereof, directly or systemically, a cell activity-reducing effective amount of lycopene. Pharmaceutical composition are derscribed, for inhibiting the growth of cancer cells, comprising as an active ingredient a cancer cell growth-inhibiting effective amount of lycopene. <IMAGE>
Patent DK-0644332-T3 (DK)
Inventor: JUENEMANN ALFONS
IPC: F04C29/06
Filed: 1994-09-19
Granted: 1997-07-21
Abstract: Liquid ring (fluid ring) gas pump with a flow path for the gas-liquid mixture leaving the pumping chamber and a noise suppression (silencing) device which is formed by a buffer chamber (4) which, with its opening, adjoins the flow path and is otherwise essentially closed, and which partially fills with gas and acts as a pressure pulse attenuator and silencer with respect to the gas-liquid mixture flowing past. To this end it expediently extends vertically, with a length which is large compared with its width and its opening cross-section. <IMAGE>
Patent DK-0657395-T3 (DK)
Inventor: MOIREAU PATRICK
IPC: C03C25/26
Filed: 1994-12-02
Granted: 1999-11-15
Abstract: Process for the production of sized glass filaments consisting in coating the glass filaments with a size capable of polymerizing thermally, consisting of a solution whose solvent content is lower than 5 % by weight and viscosity lower than 400 cP, the said solution including a thermally polymerisable and/or crosslinkable base structure, the said structure including at least 60 % by weight of one or more components of molecular mass lower than 750, containing at least one acrylic and/or methacrylic and/or vinyl ether and/or N-vinylamide and/or N-vinyllactam functional group, the proportion of polyfunctional component(s) within the said components being at least 45 % by weight of the said components, so as to obtain glass filaments coated with an unpolymerised size capable of polymerising thermally. The invention also relates to the sized glass filaments obtained and the composites produced from the said filaments.
Patent DK-0679156-T3 (DK)
Inventor: HOLTON ROBERT A
IPC: C07C271/22
Filed: 1994-01-14
Granted: 2000-09-04
Abstract: A process for abstracting a C10 hydroxy, acyloxy or sulfonyloxy substituent from a taxane in which the C10 hydroxy, acyloxy or sulfonyloxy substituted taxane is reacted with samarium diiodide.
Patent DK-0679777-T3 (DK)
Inventor: WOEHRN VOLKER
IPC: E05C1/04
Filed: 1995-03-28
Granted: 2000-01-31
Abstract: The roof window has a main frame on which is fitted a pane (2) by means of a bearing. The pane is openable so far around a pivot axis that the outside (4) of the pane is accessible for its cleaning from the room side (6) and in this cleaning position the pane is fixable against the main frame by means of a bolt (7) movable by hand on the upper cross rail (8) of the pane. The bolt works in conjunction with a closure housing (10) on the longitudinal arm (11) of the main frame near its lower cross arm. The closure tongue (25) of the bolt is provided with a nose function (26) for engaging behind a rib (30) limiting the closure aperture (29) of the closure housing. <IMAGE>
Patent DK-0738152-T3 (DK)
Inventor: JOHNSON LORIN K
IPC: A61K31/655
Filed: 1995-01-06
Granted: 2006-01-30
Abstract: The present invention provides a method of colon cancer chemoprevention or chemotherapy comprising administering to an individual suffering from colon cancer or at risk to develop colon cancer a pharmaceutical composition comprising an effective amount of a 2-hydroxy-5-phenylazobenzoic acid derivative or an ester of an active metabolite thereof, or a pharmacologically acceptable salt of the 2-hydroxy-5-phenylazobenzoic acid derivative or an ester or an active metabolite thereof.
Patent DK-0666871-T3 (DK)
Inventor: KUNZ HERBERT
IPC: C08B30/04
Filed: 1994-06-28
Granted: 1999-06-07
Abstract: PCT No. PCT/DE94/00755 Sec. 371 Date May 31, 1995 Sec. 102(e) Date May 31, 1995 PCT Filed Jun. 28, 1994 PCT Pub. No. WO95/06667 PCT Pub. Date Mar. 9, 1995In the process, a starch-containing suspension 1 is divided at admixture of washing liquid 5 in a centrifuge "A" into starch-containing concentrate 2, a first liquid phase 3 with primarily dissolved substances and a second liquid phase 4 with primarily undissolved substances. The first liquid phase 3 is especially suitable as washing liquid in counterflow washing processes as it contains no obstructive undissolved substances. Also, the disposal of this liquid phase is simpler. The second liquid phase 4 with the undissolved substances is generated in higher concentration compared to conventional processes so that the processing of this phase is less cumbersome.
Patent DK-0748315-T3 (DK)
Inventor: FORTIN MICHEL
IPC: C07D233/84
Filed: 1995-02-27
Granted: 2004-03-15
Abstract: Use of tetra-substd. imidazole derivs. of formula (I), their enantiomers and diastereomers and their acid and base addn. salts, to treat disorders arising from abnormal stimulation of angiotensin II receptors AT1 and AT2, is new. R1 = 1-6C alkyl, alkylthio, alkoxy, aryl, arylthio, aryloxy or aryl(1-6C)alkyl; R2 = -S-R, -O-R, -C(OH)(R)-COOH; halo; or -C(=O)Z; R = 1-8C alkyl, 2-8C alkenyl, 3-6C cycloalkyl or aryl (all opt. substd.); Z = OH, alkoxy or carboxy; R3 = carboxy, acyl halo, 1-8C alkyl, 2-8C alkenyl or alkylthio, aryl, aryl(1-6C)alkyl or aryl(2-6C)alkenyl; R4 = -(CH2)ml-COOR14, -(CH2)ml-CONHR14, -(CH2)ml-CN, -SO2-NH-SO2-R14, -NH-SO2-R14, -PO3R14, SO2NHSO2NR14R15, -SO2NHSO2N(-CH2-CH2-)2D, -SO2-W-R14, etc.; m1 = 0-4; D = O or S; W = -NR15-, -NH-CO-, -NH-CO-O-, -N=CH-N-R15-, or -NH-CO-NR15-; R14, R15 = H, 1-8C alkyl, 2-8C alkenyl, 3-6C cycloalkyl or aryl; or NR14R15 = pyrrolyl, pyrrolinyl, pyrrolidinyl, piperazinyl, alkylpiperazinyl, phenylpiperazinyl, morpholinyl or indolinyl; alkyl radicals are opt. interrupted by one or more heteroatoms (O, N or S); S atoms are opt. oxidised to sulphone or sulphoxide.
Patent DK-0768882-T3 (DK)
Inventor: LANDGRAF KARL-FRIEDRICH
IPC: A61K9/58
Filed: 1995-06-22
Granted: 1999-05-25
Abstract: PCT No. PCT/DE95/00805 Sec. 371 Date Apr. 24, 1997 Sec. 102(e) Date Apr. 24, 1997 PCT Filed Jun. 22, 1995 PCT Pub. No. WO96/01112 PCT Pub. Date Jan. 18, 1996An oral administration carbamazepine medicament with a retarded active substance release is disclosed. An aqueous plasticised polymer dispersion is applied on carbamazepine crystals without causing formation of carbamazepine dihydrate. The carbamazepine crystals with their aqueous coating may be mixed with appropriate auxiliarly substances, shaped into divisible tablets or filled into capsules.
Patent DK-0804536-T3 (DK)
Inventor: MASTERS RONALD ANTHONY
IPC: C11D10/02
Filed: 1995-07-21
Granted: 2000-05-08
Abstract: Detergent compositions having good filming/streaking characteristics contain effective amounts of specific substantive materials to increase the hydrophilicity of the glass. Preferred formulas contain a amphoteric, including zwitterionic, and optionally, but preferably, anionic detergent surfactant at levels (e.g., from about 0.02 to about 15%); hydrophobic solvent; alkaline material, especially volatile alkaline materials comprising monoethanolamine or certain beta-amino-alkanol compounds; and salt of polycarboxylate, preferably polyacrylate, polymer at effective levels (e.g., from about 0.01% to about 10%, by weight of the composition).