baber/WOPTO huggingface dataset:
Patent IL-75596-A0 (IL)
Title: 8-alkylthio-2-piperazino-pyrimido-(5,4-d)pyrimidines,their preparation and pharmaceutical compositions containing them
IPC: A61P35/00
Filed: 1985-06-21
Abstract: The invention relates to new compounds of general formula    <IMAGE> (I)  wherein R1 represents an alkyl group, R2 represents a hydrogen atom, an alkyl group optionally substituted (except at the  alpha carbon atom) by a hydroxy group, or represents a cycloalkyl group or an allyl, phenyl or benzyl group, R3 represents an allyl group, an alkyl group optionally substituted (except at the  alpha  carbon atom) by a hydroxy group, or represents a cycloalkyl group or R2 and R3 together with the nitrogen atom between them represent a straight-chained alkyleneimino group, the acid addition salts thereof, particularly the acid addition salts thereof with physiologically acceptable inorganic or organic acids which have valuable pharmacological properties, particularly a metastasis-inhibiting effect based on their selective tumour-PDE inhibiting effect, and pharmaceutical compositions containing these compounds or the physiologically acceptable acid addition salts thereof. The new compounds may be prepared according to methods known for analogous compounds.
Patent IL-99326-A0 (IL)
Title: Self-supporting woven vascular graft
IPC: D03D15/00
Filed: 1991-08-28
Abstract: A woven synthetic fabric tubular vascular graft including, a stiffening component in the filling yarn is self supporting without crimping the walls of the graft. The graft is woven from warp ends of multifilament polyester yarns and elastomeric yarns in the warp and a filling yarn which includes multifilament and monofilament polyester yarns which have been twisted together. Longitudinal and radial compliance provide for improved kink resistance making the tubular grafts suitable for use in medium and small diameter peripheral applications. A preferred graft has an outer velour surface and a smooth inner surface.
Patent AU-PM453994-A0 (AU)
Title: Non-heeling monohull yacht
IPC: B63H9/06
Filed: 1994-03-18
Abstract: PCT No. PCT/AU95/00143 Sec. 371 Date Dec. 16, 1996 Sec. 102(e) Date Dec. 16, 1996 PCT Filed Mar. 17, 1995 PCT Pub. No. WO95/25663 PCT Pub. Date Sep. 28, 1995A yacht (10) includes a mast (12) that is mechanically connected to a keel (14) via a bearing (16), located in the base of hull (18) of the yacht (10). A sail foil (30) is pivotally mounted to the top of the mast (12) via a rotating bearing (34). In use, as the wind forces the sail foil (30) and mast (12) to leeward, a corresponding movement to windward is induced in the keel (14) and thus the yacht's hull (18) can remain substantially horizontal with respect to surrounding flat water.
Patent IL-102524-A0 (IL)
Title: Apparatus for the handling of electrophoretic transfer membranes and for the chemiluminescent detection of blots contained thereon,and processes using the apparatus
IPC: G01N27/447
Filed: 1992-07-16
Abstract: Improved apparatus for the handling and detecting of an electrophorectic transfer membrane is disclosed herein, the improvement comprising guide apparatus designed to accomodate the transfert membrane, a pressure head positioned relative to the guide apparatus to releasably engage the membrane, and light shielding apparatus positioned relative to the guide apparatus to selectively enclose about the transfer membrane. The apparatus is operated so that the pressure head engages a flexible portion of the transfer membrane containing an electrophoretic blot while it is in a position appropriate for detection. There is also disclosed herein a process for utilizing the apparatus of the invention. In the process drying and optionally heating of the membrane where the blot has been contacted with enzyme-triggered 1,2-dioxetanes, to enhance the resulting chemiluminescent signal, is disclosed.
Patent IL-104473-A0 (IL)
Title: Natural coloring products
IPC: A23L5/40
Filed: 1993-01-21
Abstract: A coloring material comprises as the color-imparting agent chromoplast particles containing crystalline lycopene. A process for preparing the coloring material is described.
Patent IL-105475-A0 (IL)
Title: Pharmaceutical compositions containing 1alpha,24(r)-dihydroxy-22(e)-dehydro-vitamin d3 for treating osteoporosis
IPC: A61P43/00
Filed: 1993-04-21
Abstract: A method of treating osteoporosis comprising the administration of an effective amount of 1 alpha ,24(R)-dihydroxy-22(E)-dehydro-vitamin D3.
Patent IL-111521-A0 (IL)
Title: Polyol ester lubricants for refrigerating compressors and processes for using the same
IPC: C10M105/38
Filed: 1994-11-03
Abstract: A high quality lubricant for compressors operated during at least part of their compression cycle at temperatures above normal human comfort temperatures, such as most automotive air conditioners, especially those using chlorine free hydrofluorocarbon refrigerant working fluids, is provided by mixed esters of hindered polyols, most desirably pentaerythritol, with a mixture of carboxylic acids including at least some iso-pentanoic acid along with one or more of iso-nonanoic acid, iso-octanoic acid, and dibasic acids such as adipic. When the mixture includes about 7 % adipic and amounts of branched C8-9 and C5 monobasic acids in a ratio of at least 0.75:1.00, the esters formed have excellent solubility for paraffinic and naphthenic mineral oils and are therefore especially well suited for lubricating vehicle air conditioners formerly containing chlorine containing heat transfer fluids and mineral oil lubricants.
Patent IL-112674-A0 (IL)
Title: Liquid ophthalmic sustained release delivery system
IPC: A61K47/36
Filed: 1995-02-16
Abstract: Disclosed is a sustained release liquid aqueous ophthalmic delivery system and a method of providing a slow and sustained release of ophthalmic treating agents to the eye of a mammal which comprises administering to the eye of a said mammal an effective amount of a homogeneous liquid aqueous ophthalmic pharmaceutical composition, of pH between about 3.0 and about 6.2, which is adminstrable in drop form and which comprises an ophthalmically effective concentration of a said ophthalmic treating agent and about 0.05% to about 10% by weight of the polymer chitosan; said polymer consisting essentially of (A) monomeric  beta (1->4)-D-glucosamine linked units and of (B) monomeric  beta (1->4)-D-glucosamine linked units which are scattered randomly in the molecule of the polymer, the numerical proportions of A and B being from about 60 to about 99% of A and about 1 to about 40% of B, the viscosity rating being from about 3 to about 3000 cps; in which method, upon contact with the higher pH of the ocular fluid, said liquid formulation is converted to a stiff gel from which the ophthalmic treating agent is slowly released over a prolonged period of time.
Patent IL-125968-A0 (IL)
Title: Bioactive compounds
IPC: C07C217/08
Filed: 1997-02-27
Abstract: Novel bioactive compounds which when applied to plants in bioregulatory amounts, enhance plant development responses, resulting in enhanced plant properties such as increased total biomass, increased yield, and increased plant quality. Some of the compounds increase the content of taxol and related taxanes in yew plants. One compound, 2-[diethylaminoethyl]-2-methylpropylether causes plants treated with the compound to have resistance to chewing insects. The compound 2-[diethylaminoethyl]-2-methyl-2-phenylpropylether causes plants treated with the compound to have resistance to sucking insects.
Patent IL-127216-A0 (IL)
Title: Antibodies to the ed-b domain of fibronectin their construction and uses
IPC: C12N15/09
Filed: 1997-05-23
Abstract: According to the present invention there is provided a specific binding member which is specific for and binds directly to the ED-B oncofoetal domain of fibronectin (FN). The invention also provides materials and methods for the production of such binding members.
Patent IL-139381-A0 (IL)
Title: Handwritten and voice control of vehicle components
IPC: H04Q9/00
Filed: 1999-05-06
Abstract: A recognition system for use in a vehicle or the like includes a handwriting recognizer and a voice recognizer for receiving handwriting and voice signals and a control unit to communicate a command signal associated with one, the other or a combination of both of the voice and handwritten inputs to at least one appliance. Such appliances may include, but are not limited to, car alarms, electronic windows, personal computers, navigation systems, and audio and telecommunications equipment.
Patent IL-141395-A0 (IL)
Title: Catheter, method and apparatus for generating an electrical map of a chamber of the heart
IPC: A61M25/00
Filed: 2001-02-12
Abstract: A novel apparatus and method for rapidly generating an electrical map of a chamber of a heart utilizes a catheter including a body having a proximal end and a distal end. The distal end has a distal tip and an array of non-contact electrodes having a proximal end and a distal end and at least one location sensor. Preferably, two location sensors are utilized. The first location sensor is preferably proximate to the catheter distal tip and the second location sensor is preferably proximate to the proximal end of the non-contact electrode array. The catheter distal end further preferably includes a contact electrode at its distal tip. Preferably, at least one and preferably both of the location sensors provide six degrees of location information. The location sensor is preferably an electromagnetic location sensor. The catheter is used for rapidly generating an electrical map of the heart within at least one cardiac cycle and preferably includes cardiac ablation and post-ablation validation. <IMAGE>
Patent IL-147499-A0 (IL)
Title: Pharmaceutical composition containing fenofibrate and preparation method
IPC: A61K47/20
Filed: 2000-07-07
Abstract: Pharmaceutical composition comprises micronized fenofibrate, a surfactant and a cellulose derivative that acts as both a binder and a solubilizing agent. Independent claims are also included for the following: (1) production of the composition by spraying neutral microgranules with an aqueous suspension containing the surfactant, the cellulose derivative and micronized fenofibrate and (2) production of the composition by granulating a mixture of the surfactant, the cellulose derivative and micronized fenofibrate with an aqueous wetting solution and drying and screening the granules.
Patent IL-157840-A0 (IL)
Title: Organic compounds having a core-shell structure
IPC: C08G75/20
Filed: 2003-09-10
Abstract: Compounds (I) have a core-shell structure with a core formed of multifunctional units and a shell of linear conjugated oligomeric chains that are saturated at the terminal bonding point through a flexible non-conjugated chain.  Independent claims are included for:  (1) a process for the production of compounds (I) by production of oligomers or polymers by organometallic reactions;  (2) electronic components containing compounds (I) as semi-conductors.
Patent IL-185868-A0 (IL)
Title: Human autism susceptibility gene encoding a transmembrane protein and uses thereof
Filed: 2007-09-10
Abstract: The present invention discloses the identification of a human autism susceptibility gene, which can be used for the diagnosis, prevention and treatment of autism and related disorders, as well as for the screening of therapeutically active drugs. The invention more specifically discloses that the ATP2B2 gene on chromosome 3 and certain alleles thereof are related to susceptibility to autism and represent novel targets for therapeutic intervention. The present invention relates to particular mutations in the ATP2B2 gene and expression products, as well as to diagnostic tools and kits based on these mutations. The invention can be used in the diagnosis of predisposition to, detection, prevention and/or treatment of Asperger syndrome, pervasive developmental disorder, childhood disintegrative disorder, mental retardation, anxiety, depression, attention deficit hyperactivity disorders, speech delay or language impairment, epilepsy, metabolic disorder, immune disorder, bipolar disease and other psychiatric and neurological diseases including schizophrenia.
Patent IL-199670-A0 (IL)
Title: Cap for an atomiser
Filed: 2009-07-02
Abstract: The invention relates to a cap comprising a base with means for fixing it to a container, a top fixed to the base by a hinge, closure means consisting of a first closure means and a second closure means, one on the base and the other on the top, the closure means working together to keep the top in a first position in which it is closed against the base, release means for moving apart from each other the first closure means and the second closure means and means for lifting the top. In accordance with the invention, the means for lifting the top consist of at least one leaf spring, one of whose ends is fixed to the base and the other of whose ends is able to slide on the bowl of the top, the leaf spring being under tension when the top is closed, and being relaxed or partially relaxed when the top is in the fully open position. This cap is particularly intended for use as a spray head for a spray device.
Patent MC-2096-A1 (MC)
Inventor: PETER DAVID DAVIS
IPC: C07D487/04
Filed: 1990-02-16
Abstract: The pyrrole derivatives of the formula <IMAGE> in which R<1> to R<8>, R, X, Y and m have the meaning given in the description, are therapeutically active substances, in particular for use as substances having antiinflammatory, immunological, oncological, bronchopulmonary and cardiovascular activity or as active substances in the treatment of asthma or AIDS. They are prepared from corresponding furandione derivatives in which X and Y stand for =N-R or O.
Patent LU-69986-A1 (LU)
IPC: C07C241/00
Filed: 1974-05-03
Abstract: 1458595 Isocyanate preparation ATLANTIC RICHFIELD CO 3 May 1974 [4 May 1973 8 March 1973] 19578/74 Heading C2C Isocyanates are prepared by thermally decomposing an ester of a carbamic acid having the formula R(NHCOOR<SP>1</SP>) x  or (RNHCOO) x R<SP>1</SP> wherein each R is an optionally substituted mono-, di- or tri-valent organic radical selected from saturated and monoolefinic unsaturated straight and branched chain aliphatic and cyclealiphatic radicals of not more than 32 carbon atoms, alkoxyalkyl radicals of not more than 32 carbon atoms, and aryl, aralkyl and alkaryl radicals having 1 to 5 rings; each R<SP>1</SP> is an optionally substituted mono-, di- or tri-valent organic radical selected from saturated and monoolefinic unsaturated straight and branched chain aliphatic and cycloaliphatic radicals of not more than 32 carbon atoms, alkoxy-alkyl radicals of not more than 32 carbon atoms, and aryl, aralkyl and alkaryl radicals containing 1 to 3 rings; and x is 1, 2 or 3; at from 175‹ to 350‹ C. while said ester is dissolved in an inert solvent to produce an isocyanate and an alcohol, the solvent being a compound or mixture of compounds which is (a) a solvent for said ester, (b) liquid and stable at the decomposition temperature and (c) nonreactive with isocyanate product, and selected from optionally halo- and mono-nitro-substituted C 4  to C 32  aliphatic hydrocarbons, cycloaliphatic hydrocarbons, aromatic hydrocarbons having 1 to 3 rings, (C 1  to C 15  alkyl)benzenes, halo- and mono-nitro-derivatives of the aromatic hydrocarbons and alkylbenzenes, and C 4  to C 32  ethers, ketones and carboxylic esters and their sulphur analogues.
Patent LU-72542-A1 (LU)
IPC: C07C41/05
Filed: 1975-05-20
Abstract: 1506312 Tertiary alkyl ethers SNAMPROGETTI SpA 13 May 1975 [21 May 1974] 20209/75 Heading C2C A tertiary alkyl ester is produced by reacting an alcohol with an olefin having a carboncarbon double bond on a tertiary carbon atom in the presence of an ion-exchange resin in atleast two stages, whereinin one stage the alcohol is present in excess and in another stage the olefin is in excess. The reaction may be carried out using two reactors; all of one reactant is fed to one reactor while all or part of the other reactant is fed to the other reactor, and reaction products are at least in part circulated from one reactor to the other. The invention is exemplified by the reaction of isobutene in a mixed olefin stream with methanol to form methyl tertiary butyl ether. A suitable apparatus is described. Reference has been directed by the Comptroller to Specification 1,176,620.
Patent MA-25142-A1 (MA)
Title: Procedes de separation de solides mineraux
Inventor: DONALD ALLEN LUKE
IPC: B01D21/01
Filed: 2000-03-09
Abstract: LA FORMATION DE SOLIDES DE SURFACE PENDANT LA SÉDIMENTATION D'UNE SUSPENSION MINÉRALE FLOCULÉE EST MINIMISÉE EN FLOCULANT LA SUSPENSION AVEC UN AGENT DE FLOCULATION EN PRÉSENCE DE TENSIO-ACTIF, À CONDITION QUE L'AGENT DE FLOCULATION ET LETENSIO-ACTIF NE SOIENT PAS CONTRE-IONIQUES.
Patent MA-27328-A1 (MA)
Title: Composition de pramipexole ne consistant pas en une composition de pramipexole a liberation prolongee
Inventor: AMIDON GREGORY E
IPC: A61P25/16
Filed: 2005-01-25
Abstract: DEPOSANT Société dite : PHARMACIA CORPORATION REVENDICATIONS DE PRIORITES US 25 juillet 2002 60/398,427 US 25 juillet 2002 60/398,447 US 18 juin 2003 60/479,513 Composition de pramipexole ne consistant pas en une composition de pramipexole à libération prolongée Une composition pharmaceutique à libération prolongée, sous forme d'un comprimé pouvant être administré par voie orale, comprend un sel hydrosoluble de pramipexole, dispersé dans une matrice comprenant un polymère hydrophile et un amidon ayant une résistance à la traction d'au moins environ 0,15 kN cm-2, à une fraction en matière solide représentative d'un comprimé.
Patent MA-20150065-A1 (MA)
Title: Nouveaux dérivés d'acide indanyloxydihydrobenzofurannylacétique et leur utilisation comme agonistes du récepteur gpr40
Inventor: HAMPRECHT DIETER
IPC: C07D417/12
Filed: 2013-03-25
Abstract: La présente invention concerne des composés de formule générale i, dans laquelle les groupes r1, r2 et m sont définis comme dans la revendication 1, qui présentent des propriétés pharmacologiques précieuses, en particulier la liaison au récepteur gpr40 et la modulation de son activité. Ces composés conviennent pour le traitement et la prévention de maladies qui peuvent être influencées par ce récepteur, telles que des maladies métaboliques, en particulier le diabète de type 2.
Patent MA-43602-A1 (MA)
Title: Procédé et dispositif de levage automatique des véhicules
Inventor: SAOUD ADNANE
IPC: B60S9/10
Filed: 2018-10-31
Abstract: L’invention concerne un procédé de levage automatique des véhicules caractérisé en ce que l’utilisateur appuie sur un bouton dans le tableau de bord pour actionner le levage et l’éclairage du bas de châssis de véhicule. Cette invention permet d’assurer une meilleure sécurité pour l’opérateur ainsi d’avoir un temps d’exécution de l’entretien plus rapide. L'invention concerne en outre un dispositif pour la mise en œuvre dudit procédé.
Patent MA-44025-A1 (MA)
Title: Inhibiteurs de pde9 pour le traitement de maladies périphériques
Inventor: SVENSTRUP NIELS
IPC: A61P13/08
Filed: 2017-06-30
Abstract: La présente invention concerne des inhibiteurs de pde9, leur synthèse et leur utilisation pour le traitement de l'hyperplasie bénigne de la prostate, de la thalassémie bêta et de la drépanocytose.
Patent MA-58655-A1 (MA)
Title: Acide nucléique optimisé par codons qui code la protéine smn1
Inventor: MADERA DMITRIY ALEKSANDROVICH
IPC: A61K35/761
Filed: 2021-06-02
Abstract: La présente invention se rapporte au domaine de la génétique, de la thérapie génique et de la biologie moléculaire. L'invention concerne plus précisément un acide nucléique optimisé par codons séparé qui code la protéine smn1 (protéine de survivance des neurones moteurs), une cassette d'expression et un vecteur à base de celle-ci, ainsi qu'un virus recombinant à base de aav9 (virus adéno-associé de sérotype 9) afin d'augmenter l'expression du gène smn1 dans des cellules cibles, ainsi que l'utilisation de celui-ci.
Patent SG-93223-A1 (SG)
Title: Corneal vacuum centering guide and dissector
Inventor: BRYAN LOOMAS
IPC: A61B17/30
Filed: 1993-04-07
Abstract: A single bladed dissector blade assembly suitable for forming a generally circumcorneal interlamellar channel in an eye, comprising:   a blade having a dissecting end, a support end, and a cross-section, said blade being in the form of a major arc in a plane perpendicular to a rotational axis thereof; and a blade support arm having a first end and a second end, said first end of said support being attached at one end to the support end of the blade.   <IMAGE>
Patent UY-25444-A1 (UY)
Title: Retrete simple con cisterna con cubeta
Inventor: HENNESSY ARNOLD
IPC: E03D1/20
Filed: 1999-03-24
Abstract: Aparato de descarga con cubeta para ser utilizado en un retrete de forma y apariencia convencionales, y de construcción y operación sencillas. El aparato incluye de descarga se encuentra ubicada dentro de un tanque de forma convencional y que generalmente se coloca a una altura relativamente baja. El aparato incluye una cubeta (50) colocada en un tanque convencional (44) de longitud lateral larga (A) y de profundidad corta desde el frente hasta la parte trasera (B), en el que el tanque está colocado en la parte trasera (40) de la pieza de taza del retrete (20). La cubeta tiene una longitud lateral (Q) de al menos el 150% de la profundidad (E) de la cubeta, y rota en torno a un eje lateral (52) dentro del tanque. Al menos uno de los extremos de la cubeta está fijado a un muñón que se extiende a través de un cojinete en un orificio en el tanque y que está fijado a una palanca (64) ubicada en el exterior de una de las paredes en los extremos del tanque, resultando la rotación de la palanca en la rotación de la cubeta. Hay un deflector en el fondo del tanque a un lado del orificio de salida del agua para reducir las salpicaduras y para concentrar el agua cerca del orificio de salida. Al menos uno de los extremos de la cubeta es redondeado en forma de un semicírculo como lo muestra una vista horizontal, para proporcionar espacio para un caño de entrada de agua.
Patent UY-29542-A1 (UY)
Title: Nuevos herbicidas
Inventor: ELLIOTT ALISON CLARE
IPC: C07D231/14
Filed: 2006-05-18
Abstract: Se presentan nuevos compuestos de tiazol de fórmula (I) adecuado para el empleo como herbicidas. También se reivindican compuestos intermediarios de fórmula (II), así como tres procesos para la preparación de compuestos de fórmula (Ih), y un proceso para la preparación de compuestos de fórmula (IVa), en todos los cuales compuestos referidos los sustituyentes son tales como se definieron en la Memoria Descriptiva y en la Reivindicación 1.
Patent ES-175675-A1 (ES)
Title: PERFECCIONAMIENTOS EN TRACTORES AGRiCOLAS
IPC: B62D59/00
Filed: 1946-11-13
Abstract: Perfeccionamientos en los tractores que incluyen un tractor de la clase descrita que tiene un motor y ruedas motoras y un mecanismo de cambio de marchas y embrague asociado interpuesto entre ellos un conjunto de transmisión de la fuerza dotado de uno o más medios de suministro de la fuerza dispuestos al exterior y una conexión de impulsión directa entre dicho motor y dicho conjunto independiente de dicho mecanismo de cambio de marchas y embrague asociado.
Patent ES-185086-A1 (ES)
Title: PERFECCIONAMIENTOS EN LA FABRICACIoN DE CONDUCTORES DE ALTA TENSIoN, PARTICULARMENTE DESTINADOS AL ENCENDIDO DE MOTORES DE COMBUSTIoN INTERNA
Filed: 1948-08-30
Abstract: Perfeccionamientos en la fabricación de conductores de alta tensión particularmente destinados al encendido de motores de combustión interna caracterizados porque para suprimir la producción de radio-interferencias engendradas en el sistema de encendido por chispa de un motor de combustión interna se distribuye uniformemente a lo largo de un conductor resistencia ohmica suficiente para suprimir las oscilaciones indeseadas.