baber/WOPTO huggingface dataset:
Patent GB-1317961-A (GB)
Title: Pneumatic striking device
IPC: B25H1/00
Filed: 1970-05-29
Abstract: 1317961 Pneumatic striking device DIOSGYORI GEPGYAR 29 May 1970 25908/70 Heading B4C A pneumatic striking device, e.g., for driving a first element 30 into a second element 12, comprises a striker piston and cylinder assembly 1 and a yoke 2 for suspending the device and means 10 for connecting the device to the element 12 or the member being struck, the connecting means being angularly adjustable relative to the yoke 2 about an axis X along which the device acts. The yoke 2 may be suspended by rings 3, 4, and supports a compressed air cylinder 5 having a piston 9 and rod 11 for connection through a chain 10 and hook 13 to the element 12. The piston 9 is operable by means of a valve 17 controlling compressed air supply from a main 23 through conduits 21, 18, 14, to draw the suspended device towards the element 12 so that a hammer 29 engages the elements 30. For driving the element 30 a rotary valve 24 is actuated to deliver compressed air alternately into a first cylinder chamber 25 and, through a duct 26, to a counter chamber 27, thus reciprocating a striker piston 28 to deliver blows to the hammer 29 and thus cyclically to element 30. For angular adjustment, the cylinder 5 is attached to a disc 32a in rotatable co-operation through up to 350 degrees with a further disc 32 fixed to the assembly 1, a spring- loaded locking pin 33 allowing angular setting. Also, a lug 7 enables the cylinder 5 to be fixed to the yoke 2. For vertical operation, the device may be suspended through alternative rings 34, 35, e.g., for deslagging furnace bottoms. The device is mentioned also as useful for forcing bushes in or out.
Patent GB-1318517-A (GB)
Title: Unsaturated polyesters their production and use
IPC: C08G63/553
Filed: 1969-11-06
Abstract: 1318517 Laminates SCOTT BADER CO Ltd 2 Dec 1970 [6 Nov 1969] 54457/69 Heading B5N [Also in Divisions C3 and D1] A laminate comprises polyethylene or cellophane (TM) backing sheets on each side of a glass fibre mat or fabric which is impregnated with an unsaturated polyester resin. The backing sheets may be stripped off to obtain an impregnated glass fibre mat or fabric which can be moulded. The polyethylene backed laminate may be produced by passing the assembly between rollers, and the cellophane backed laminate by allowing the assembly to lie on a heated surface. The impregnant, which is placed between two sheets of glass fibre mat or fabric, is (a) a solid unsaturated polyester resin which comprises an unsaturated polyester containing the residues of a glycol component at least 55 mole per cent of which comprises 1, 4-cyclohexane dimethanol and of an acid component of which at least 50 mole per cent comprises fumaric acid and 0 to 50 mole per cent comprises a saturated dicarboxylic acid, and 10 to 60% by wt. of at least one a, #-ethylenically unsaturated monomer; (b) a resin composition which comprises 10 to 60% by wt. of an a, #- ethylenically unsaturated monomer and a mixture of at least 50% by wt. of the unsaturated polyester of (a) and at least one other unsaturated polyester which is such as to form a liquid resin when mixed alone with the monomer in whatever proportion; or (c) a resin composition which comprises at least 50% by wt. of the solid unsaturated polyester resin (a) and a liquid unsaturated polyester resin. Examples of glycols, acids and monomer are given.
Patent GB-1318930-A (GB)
Title: Microelectronic circuit arrangement and method of manufacture  thereof
IPC: H01L23/525
Filed: 1970-12-01
Abstract: 1318930 Component assemblies; semiconductor devices ARBEITSSTELLE FUR MOLEKULARELEKTRONIK 1 Dec 1970 57118/70 Headings H1K and H1R In a microelectronic circuit arrangement comprising a plurality of identical subsystems with a common output, driven by a common input signal, to avoid metallic contamination when input and output lines of defective subsystems are broken, each subsystem is isolated by reverse-biased diodes in the input and output lines, the diodes of non-defective subsystems being rendered conductive by high-voltage pulses, after testing. The Figure shows subsystems I and II, which may be NAND gates, I being initially decoupled from the inputs 7, 8 and output 9 by reversebiased diodes 10, 11 and diode pair 12, II being similarly decoupled by 13, 14, 15.
Patent GB-1321617-A (GB)
Title: Desks
IPC: A47B13/00
Filed: 1969-12-15
Abstract: 1321617 Desks; separate feet A ARENSON Ltd 27 Aug 1970 [15 Dec 1969] 60955/69 Heading A4H and A4U In the desk of Specification 1244170 the side legs (7', 15 and 7, 15) at one or both sides of each frame are omitted when a pedestal (24) is provided under that side of the top member 1, and the or each pedestal has one or more depending legs (120), Fig. 1 (not shown). Moulded resin shoes 100 are fixed to the upper front side parts 44 of the pedestal by screws 103. The outer shoe 100, Fig.2 is secured to the end of front rail 8 by a screw 109 passed through a counter sink 108 in a cap 107 of rail 8 and a counter sunk bore 105 in the shoe. The inner shoe Fig.3 (not shown) is secured to rail 8 by a plate (51) and a bolt (55). Each pedestal leg (120) is carried by a plate (121) screwed to the pedestal. The rear undersurface 119, Fig.5 of the pedestal has plates 113 screwed thereto, each plate 113 having a rearwardly open counter sunk slot 114 in which a countersunk screw 116 in the lower edge 118 of a rear board 20 is tightened. The lower rear crossrail (16) of the construction described in Specification 1244170 is omitted, and the upper edge of board 20 locates in a channel (112), Fig.4, (not shown) of rail (14), and screw (22) does not penetrate spigot (34).
Patent GB-1340066-A (GB)
Title: Wall fittings for electric light switches
IPC: H02G3/14
Filed: 1970-10-21
Abstract: 1340066 Switch covers J D BEARDMORE & CO Ltd 13 Dec 1971 [21 Oct 1970] 35314/70 Heading H1N A plate 9, slotted as at 10 to receive the or each manually actuable element 6 of an electric light switch, seats in a rebate 7, of right-angled cross-section, in a separately formed rim 1 which is thereby clamped when the plate 9 is fixed to a supporting surface.
Patent GB-1347027-A (GB)
Title: Piston type flow meter
IPC: G01F3/18
Filed: 1971-04-29
Abstract: 1347027 Fluid-flow meters H TATSUNO 29 April 1971 12215/71 Heading F1A In a meter comprising pistons 32 to 35 reciprocable in cylinders 8, 9, 10, 11 to drive a crank shaft 14 connected to an indicating device, the drive between the pistons and the shaft includes a lost motion device, which comprises rings 40 engaging with the crank-pin 14b whereby a projection 51 screwed into the cover 7 of at least one cylinder is adjustable to vary the capacity of the meter. The projection 51 is provided with a handle 52 having a row of holes 54 around the edge thereof and through one which a pin 53 is inserted into one of two holes 57 in the cover 7. A rotary distributor valve 12 driven by the shaft controls the supply to and exhaust from the cylinders.
Patent GB-1349111-A (GB)
Title: Package including and a packaging device for containers
IPC: B65D71/46
Filed: 1973-01-26
Abstract: 1349111 Packages JOHN WADDINGTON Ltd 26 Jan 1973 [16 Feb 1972] 7102/72 Heading B8C A packaging device comprises a blank having a base panel 10 with holes in which containers 24 can be inserted with their flanges 26 resting on the panel and fold over panels 12, 14, 16 which can be folded over the container tops and secured by glue so that the device takes the form of a shallow rectangular sectioned sleeve. The device may have a tear strip.
Patent GB-1351108-A (GB)
Title: Steering device more particularly for missiles
IPC: F41G7/22
Filed: 1962-08-22
Abstract: 1351108 Automatic control of position FLUGGERATEWERK BODENSEE GmbH 22 Aug 1962 10472/65 [Divided out of 32351/62] Heading G3R [Also in Division G1] A missile target seeking head 300 freely suspended and rotating in space comprises a saturable premagnetized cylindrical magnet 304, an oscillator 306 being inductively coupled to the input of an amplifier 308 by windings 310, 312 on the magnet. The premagnetization of the magnet 304 may be obtained by using a permanent magnet or by the constant energization of an auxiliary coil. If the head 300 is rotating with the magnet 304 in a plane inclined in relation to an external magnetic field produced e.g. by a ship or an aircraft, the magnetization of that magnet is periodically varied and there is set up in the winding 312 a signal modulated with the frequency of revolution of the head. After demodulation by means within the amplifier 308 this signal is applied to the coil 316 of an electromagnet 314 at right angles to the magnet 304, the external magnetic field reacting with the electromagnet 314 to exert a torque causing the axis of revolution of the head 300 to be aligned parallel with the external field by a precessional movement. The magnet 304 then rotates in a plane perpendicular to the external field and no signal is generated in the winding 312.
Patent GB-1351126-A (GB)
Title: Colouration process
IPC: D06P1/90
Filed: 1970-04-29
Abstract: 1351126 Dyeing in organic media YORKSHIRE CHEMICALS Ltd 29 April 1971 [29 April 1970] 20562/70 Heading D1B Hydrophobic fibres are dyed in organic liquids with azo disperse dyes of formulae I and II in which R<SP>1</SP> R<SP>2</SP> R<SP>3</SP> and R<SP>4</SP> each represents hydrogen, chlorine or bromine or an alkoxy, hydroxyl, carbonyl, carboalkoxyl, cyano, nitro, sulphonamido, mono- or dialkylsulphonamido or alkylsulphonyl group, R<SP>5</SP> is hydrogen or a methyl group, R<SP>6</SP> is an alkylene group, R<SP>7</SP> is an alkyl group having one or more hydroxyl groups and/or one cyano group, R<SP>8</SP> is a heterocyclic group optionally substituted by at least one substituent selected from chlorine, bromine, cyano, nitro, phenyl, sulphonamido, alkoxyl, mono- and dialkyl sulphonamido, alkylsulphonyl and thiocyano groups, fibres dyed include cellulose di- and tri-acetate, polyamides, polyesters and polyacrylonitrile fibres, the organic liquid may be methylene chloride, trichloroethylene, carbon tetrachloride, dimethylformamide and tetrachloroethylene. Dispersing agents may be used, roller and screen printing methods also being specified.
Patent ID-30041-A (ID)
Inventor: MORITA TOSHIHIRO
IPC: G10L19/00
Filed: 2000-11-10
Abstract: In an information processor for checking in or out a content to an external device connected thereto, a number of possible checkouts for the content by a predetermined kind of symbol, a name corresponding to the content is displayed and a number of possible checkouts for the content is displayed. Thus, a desired content can be checked out or in simply and quickly. <IMAGE>
Patent IL-100359-A (IL)
Title: Process for rendering contact lenses hydrophilic by treating them with a bisaryl-derivative
IPC: C08J7/12
Filed: 1991-12-12
Abstract: The process is characterised in that a contact lens is treated with a compound of the formula I Ar-Z-Ar' (I> in which Ar and Ar' are, independently of one another, an aromatic radical which can be substituted by lower alkoxy and/or by lower alkyl, and in which one of the radicals Ar or Ar' or both radicals Ar and Ar' carry one or more substituents X which are selected, independently of one another, from among a polar functional group Y, lower alkyl which is substituted by a polar functional group Y, and lower alkoxy which is substituted by a polar functional group Y, and in which Z is a divalent group which separates Ar and Ar' from one another by 1 to 6 atoms. The invention likewise relates to contact lenses treated according to the invention and to the use of compounds of the formula I in the process according to the invention.
Patent IL-113896-A (IL)
Title: Prioritized image transmission system
IPC: G01S3/786
Filed: 1995-05-29
Abstract: An image transmission system and method automatically reduce the size of digital data signals transmitted from visual sensors. The system and method are completely automated and (a) use a plurality of sensors to detect targets in an area of interest, (b) direct a camera to place a target in the camera's field of view, (c) provide a digitized visual image in which the target is identified in a target box, and (d) automatically compress (or otherwise reduce the size of) a digital signal for nontarget portions of the visual image.
[US5521634A]
Patent IL-117697-A (IL)
Title: Polysiloxane-comprising perfluoroalkyl ethers, and the preparation and use thereof
IPC: B05D7/24
Filed: 1996-03-28
Abstract: PCT No. PCT/EP96/01255 Sec. 371 Date Dec. 22, 1997 Sec. 102(e) Date Dec. 22, 1997 PCT Filed Mar. 22, 1996 PCT Pub. No. WO96/31791 PCT Pub. Date Oct. 10, 1996The present invention describes a free radical polymerizable segmented macromonomer based on perfluoroelkyl ether, polysiloxane and divalent organic segments. This macromoner can be polymerized and used to form moldings, contact lenses, corneal implants and other biomedical articles.
Patent IL-121836-A (IL)
Title: cGmp pde inhibitors for use as medicaments for the oral treatment of erectile dysfunction in man
IPC: A61K/
Filed: 1994-06-02
Abstract: The use of a compound of formula (I) wherein R1 is H; C1-C3 alkyl; C1-C3 perfluomalkyl; or C3-C5 cycloalkyl; R2 is H; optionally substituted C1-C6 alkyl; C1-C3 pefluoroalkyl; or C3-C6 cycloalkyl; R3 is optionally substituted C1-C6 alkyl; C1-C6 perfluoroalkyl; C3-C5 cycloalkyl; C3-C6 alkenyl; or C3-C6 alkynyl; R4 is optionally substituted C1-C4 alkyl, C2-C4 alkenyl, C2-C4 alkanoyl, (hydroxy)C2-C4 alkyl or (C2-C3 alkoxy)C1-C2 alkyl; CONR5R6; CO2R7; halo; NR5R6; NHSO2NR5R6; NHSO2R8; SO2NR9R10; or phenyl, pyridyl, pyrimidinyl, imidazolyl, oxazolyl, thiazolyl, thienyl or triazolyl any of which is optionally substituted with methyl; R5 and R6 are each independently H or C1-C4 alkyl, or together with the nitrogen atom to which they are attached form an optionally substituted pyrrolidinyl, piperidino, morpholino, 4-N(R11)-piperazinyl or imidazolyl group; R7 is H or C1-C4 alkyl; R8 is optionally substituted C1-C3 alkyl; R9 and R10 together with the nitrogen atom to which they are attached form an optionally su
Patent IL-135126-A (IL)
Title: Perforated microparticles and methods of use and preparation thereof
IPC: A61K9/22
Filed: 2000-03-16
Abstract: Stabilized dispersions are provided for the delivery of a bioactive agent to the respiratory tract of a patient. The dispersions preferably comprise a plurality of perforated microstructures dispersed in a suspension medium that typically comprises a hydrofluoroalkane propellant. As density variations between the suspended particles and suspension medium are minimized and attractive forces between microstructures are attenuated, the disclosed dispersions are particularly resistant to degradation, such as, by settling or flocculation. In particularly preferred embodiments, the stabilized dispersions may be administered to the lung of a patient using a metered dose inhaler.
Patent IL-135724-A (IL)
Title: Respiratory mask and method of making it
IPC: A62B18/10
Filed: 1998-10-22
Abstract: A facepiece insert (26), comprising: a central portion (28); a pair of cheek portions (30) disposed on opposite sides of 3166 י' בטבת התשס" ד - January 4, 2004 the central portion by living hinges; and a chin portion (32) connected to the central portion by a living hinge.
Patent IL-136539-A (IL)
Title: Savoury cereal
IPC: A23L7/17
Filed: 2000-06-02
Abstract: Cooked-extruded-expanded savoury cereal having a porous texture and a specific weight of from 100 to 500 g/l, especially of from 150 to 350 g/l, which may be added alone or as part of a fix to eggs for preparing an egg based product, especially an omelet or scrambled eggs.
Patent IL-142293-A (IL)
Title: Layered savoury snack product
IPC: A23P30/40
Filed: 2001-03-28
Abstract: The present invention concerns a savoury snack product with two layers of a whipped and baked savoury sponge and a filling in between, wherein said sponge has an aw value comprised between 0.60 and 0.85, a pH value comprised between 3.5 and 5.5 and an overrun comprised between 30 and 170 % and the filling is a water-in-oil emulsion and has an aw value comprised between 0.60 and 0.85, a pH comprised between 3.5 and 5.5 and an overrun below 150 %.
Patent IL-142474-A (IL)
Title: Pharmaceutical formulation comprising omeprazole
Inventor: BERGSTRAND PONTUS
IPC: A61K47/38
Filed: 2001-04-05
Abstract: An enteric coated oral pharmaceutical formulation comprising as active ingredient a compound selected from the group of omeprazole, an alkaline salt of omeprazole, one of the single enantiomers of omeprazole and an alkaline salt of one of the single enantiomers of omeprazole, wherein the formulation comprises a core material that comprises the active ingredient and optionally an alkaline reacting compound, the active ingredient is in admixture with a pharmaceutically acceptable excipient, such as for instance a binding agent, and on said core material a separating layer and an enteric coating layer. A hydroxypropyl cellulose (HPC) with a specific cloud point is used in the manufacture of the claimed pharmaceutical formulations. Furthermore, the application describes the processes for their preparation and the use of the claimed formulations in medicine.
Patent IL-145298-A (IL)
Title: Process for the preparation of 1,4,7,10- tetraazacyclododecane
IPC: C07D487/16
Filed: 2001-09-06
Abstract: 1,4,7,10-Tetraazacyclodecane, a precursor for the synthesis of macrocylic chelating agents for metal ions such as gadolinium, is prepared efficiently as a highly pure product on an industrial scale.
Patent IL-154653-A (IL)
Title: Preparation of sterile articles from polymers containing a stabiliser based on a poly(oxyalkylene)
IPC: C08J7/00
Filed: 2003-02-27
Abstract: A method of preparing a sterile article is disclosed. A polymer having a halogen-containing repeating unit is prepared that contains about 0.005 to about 65 phr of a stabiliser having the general formula TGOT', where each T is independently selected from R-, R-CO-, -P(R) 2 , -P(OR) 2 , -Si( R ) 3 , or -Si(OR) 3 , T' is T or A[GOT] n , each A is independently selected from LS-Sn(R) 3-q (OLJ) q , (CH 2 ) p S-Sn(R) 3-q (S(CH 2 ) p -J) q , LCO 2 Sn(R) 3-q (OLCO-J) q , or LSn(Y) 3-q (LJ) q  when n is O, from CO, E, CO-E-CO, Si(R) 2 , Si(OR) 2 , (Si(R) 2 G) r , (CO-E-CO-G) r , (CO-G) r , or (E-G) r  when n is 1, and from P, PO and trimellitate when n is 2, Y is -SLJ, -SLJ, -SLOR, -OLJ, -OLR, -S(CH 2 ) p , each R is independently selected from R', aralkyl from C 6  to C 12 , and aryl from C 6  to C 12 , E is alkylene from C 1  to C 12 , m is 1 to 20, n is 0 to 2, p is 0 to 10, q is 0 to 3 and r is 1 to 20. An article is made from the polymer and the article is sterilised with ionising radiation.
Patent IL-162630-A (IL)
Title: Composition containing a viral vector containing a heterologous gene to be transduced into a neuron
IPC: C12N5/0793
Filed: 2004-06-20
Abstract: Methods are disclosed for delivering a heterologous gene to a cell body of a neuron by contacting a muscle tissue innervated by the neuron with a viral vector comprising a heterologous gene, wherein the viral vector enters said neuron and is retrogradely moved to the cell body. Additionally, methods for expressing secreted proteins from a nerve cell body as well as methods for treating neurodegenerative disorders such as amyotrophic lateral sclerosis are described.
Patent IL-167416-A (IL)
Title: Thiazolyl biphenyl amides , process for preparing them , compositions comprising them and a method of controlling unwanted microorganisms
IPC: C07D277/56
Filed: 2005-03-14
Abstract: N-biphenyl thiazole-5-carboxamide derivatives (I) are new.  N-biphenyl thiazole-5-carboxamide derivatives of formula (I) are new.  R1-R5 = hydrogen, halo, cyano, nitro, 1-6C alkyl, 2-6C alkenyl, 1-4C haloalkyl, (halo)alkoxy, (halo)alkylthio or (halo)alkylsulfonyl (with 1-5 halo), or 3-6C cycloalkyl, or R1 and R2, or R2 and R3, are together alkenylene, optionally substituted by halo or 1-6C alkyl;  R6 = 1-8C alkyl, 1-6C alkylsulfinyl or alkylsulfonyl, 1-4C alkoxy(1-4C)alkyl, 3-8C cycloalkyl, 1-6C haloalkyl, haloalkylS(O)n, halo1-4C alkoxy(1-4C)alkyl or halo(3-8C)cycloalkyl (each with 1-9 fluoro, chloro and/or bromo), COR7, CONR8R9 or CH2NR10R11; n = 0-2;  R7 = hydrogen, 1-8C alkyl or alkoxy, 1-4C alkoxy(1-4C)alkyl, 3-8C cycloalkyl, 1-6C haloalkyl or haloalkoxy, halo1-4C alkoxy(1-4C)alkyl, halo(3-8C)cycloalkyl (each with 1-9 fluoro, chloro and/or bromo), or 4-(difluoromethyl)-2-methyl-1,3-thiazol-2-yl;  R8 and R9 = hydrogen, 1-8C (halo)alkyl, (halo)1-4C alkoxy(1-4C)alkyl or 3-8C (halo)cycloalkyl (each with 1-9 fluoro, chloro and/or bromo), or together with the nitrogen they complete a 5-8 membered heterocycle, optionally substituted one or more times by halo and/or 1-4C alkyl and optionally containing 1 or 2 additional non-adjacent heteroatoms (oxygen, sulfur or NR12);  R10 and R11 = hydrogen, 1-8C (halo)alkyl or 3-8C (halo)cycloalkyl (each with 1-9 fluoro, chloro and/or bromo), or together complete a heterocycle as defined for R8 and R9;  R12 = hydrogen or 1-6C alkyl. An Independent claim is also included for the preparation of (I).
Patent IL-169874-A (IL)
Title: Radial engine
IPC: B64C27/14
Filed: 2005-07-25
Abstract: A four-stroke radial engine comprises cylinders arranged radially with respect to a driving shaft of said radial engine and pistons associated with said cylinders, said pistons being connected to said driving shaft by means of respective connecting rods which are rotatably supported on a same crank pivot of said driving shaft.
Patent IL-175521-A (IL)
Title: Process for the cultivation of microorganisms of the genus thraustochytriales
IPC: C12P7/64
Filed: 2006-05-09
Abstract: The invention relates to an optimized method for the production of PUFAs by cultivating microorganisms belonging to the group of Stramenopiles in a fermentation medium that is pH-stabilized using calcium carbonate and comprises 3-15 g/L CaCO3, whereupon the PUFAs are isolated from the microorganisms and/or the medium. The invention particularly relates to novel optimized media having a different CaCO3 content. By using adequate quantities of CaCO3, the process can be significantly simplified during fermentation while greater quantities of DHA can be obtained at an increased oil content in the biomass. They allow microorganisms belonging to the Stramenopiles to be fermented without controlling the pH, thereby substantially improving and significantly simplifying PUFA production.
Patent IL-176740-A (IL)
Title: Non-nucleotide reverse transcriptase inhibitors, pharmaceutical compositions comprising them and use thereof in the preparation of medicaments for the prophylaxis or treatment of hiv-1 infections
IPC: C07D409/12
Filed: 2006-07-06
Abstract: Compounds of the formula Z: where; A is CH or N; R1 is a substituent to a carbon atom in the ring containing A selected from —S(═O)pRa, where Ra is —C1-C4 alkyl, —ORx, —NRxRx, —NHNRxRx, —NHNHC(═O)ORx, —NRxOH; —C(═O)—Rb, where Rb is —CT-C4-alkyl, ORx, —NRxRx, —NHNRxRx, —NHC1-C3-alkyl-C(═O)Orx —NRxRc, where Rc is H, C1-C4 alkyl, —NRxRx; —C(=0)Rd, —CN, S(═O)pRx, where Rd is Rd is C1-C4-alkyl, —ORx, —NRxRx C1-C3-alkyl-O—C1-C3-alkylC(═O)ORx, —C1-C3-alkyl-COORx; —C1-C3alkyl-OH or C1-C4 alkyl ethers or esters thereof (O—C1-C3alkyl)q-O—Rx a 5 or 6 membered aromatic ring having 1-3 hetero atoms p is 1 or 2; Rx is independently selected from H, C1-C4 alkyl or acetyl; or a pair of Rx can together with the adjacent N atom form a ring; L is -0-, —S(═O)—, or —CH2—, where r is 0, 1 or 2; R3-R7 are substituents as defined in the specification; X is —(CR8R8′)n-D-(CR8R8′)m-; D is a bond, —NR9—, -0-, —S—, —S(=0)- or —S(=0)2-; and pharmaceutically acceptable salts and prodrugs thereof, have utility as HIV antivirals.
Patent IL-184678-A (IL)
Title: Proteasome inhibitors
Filed: 2007-07-17
Abstract: The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly or indirectly with proteasome activity.