baber/WOPTO huggingface dataset:
Patent CA-2995448-A1 (CA)
Inventor: SURJAATMADJA JIM BASUKI
IPC: E21B43/17
Filed: 2015-09-25
Abstract: A multi-oriented hydraulic fracturing (MOHF) model may incorporate the pseudo-plastic properties of the formation and tiny tectonic motions from fracturing to enhance MOHF operations. For example, a method may include modeling a simulated wellbore penetrating a simulated subterranean formation with a MOHF model having (1) static inputs and (2) dynamic inputs that comprise pseudo-plastic properties of rocks that comprise the subterranean formation; simulating a first fracture in the subterranean formation with first fracture operational parameters with the MOHF model; calculating formation stresses with the MOHF model after the first fracture; simulating a second fracture in the subterranean formation with of second fracture operational parameters with the MOHF model; and calculating a simulated fracture network characteristic for each of the plurality of first and second fracture operational parameters with the MOHF model, thereby producing several simulated fracture network characteristics that may be used for selecting the preferred operational parameters.
Patent CA-2995766-A1 (CA)
Title: Retrait d'une capsule presente sur un support de capsule
Inventor: BYUN DA MI
IPC: A47J31/36
Filed: 2016-09-16
Abstract: La présente invention concerne une machine de traitement de capsule (1) pour préparer une boisson à partir d'une capsule (5) possédant un corps (50) qui contient un ingrédient et une bride en saillie périphérique (51), ladite machine comprenant : un support de capsule (10) pourvu d'une ouverture orientée vers le haut (12) pour recevoir la capsule (5) par l'intermédiaire de l'ouverture (12) de sorte que la bride de capsule (51) s'étende généralement en parallèle par rapport à l'ouverture (12) ; et un dispositif de transfert de capsule (30) comportant un guide de capsule (31) pour guider la capsule (5) depuis le support de capsule (10) jusqu'à à une zone d'évacuation de capsules utilisées (40). Le guide de capsule (31) comprend une paire de glissières en regard (311, 312) comportant chacune une section de maintien (311a, 312a) conçue pour maintenir la capsule (5) entre les glissières (311, 312) sous la bride (51) et maintenir la capsule (5) au-dessus du support de capsule (10). Le dispositif de transfert de capsule (30) comprend un dispositif de déplacement de capsule (35) pour déplacer la capsule (5) depuis la section de maintien (311a, 312a) jusqu'à la zone d'évacuation de capsules utilisées (40).
Patent CA-2995796-A1 (CA)
Inventor: COSEGLIA JOHN
IPC: B61F5/06
Filed: 2018-02-21
Abstract: A friction shoe for a railway car truck is provided. The railway truck comprises two parallel side frames, a suspension spring assembly supported by the side frames, and a bolster transversely mounted between the side frames and supported by the suspension spring assembly. Each side frame has at least one vertical support face, and the bolster has at least one sloped support face. The friction shoe comprises a sloped wall engaging the sloped support face of the bolster, a vertical wall engaging the side frame vertical support face, and a bottom base engaging and supported by a suspension control spring group which comprises three concentrically nested coil springs which provide a normal force on the column wear plate of between 3000 and 5000 pounds in the static empty railway car truck condition and between 7,500 and 12,000 pounds force under the static loaded railway car truck condition.
Patent CA-2998705-A1 (CA)
Title: Derives de 1-phenylpyrrolidin-2-one comme inhibiteurs de perk
Inventor: AXTEN JEFFREY MICHAEL
IPC: C07D487/04
Filed: 2016-09-15
Abstract: L'invention concerne des dérivés de pyrrolidinone et d'imidazolidinone substitués. L'invention concerne spécifiquement des composés de formule I, dans laquelle R1, R2, R3, R4, R5, R6, R7, X et Y sont tels que définis dans la description. Les composés de l'invention sont des inhibiteurs de PERK et peuvent être utiles dans le traitement du cancer, des syndromes précancéreux et de maladies/lésions associées à des voies de réponse des protéines dépliées activées, telles que la maladie d'Alzheimer, la douleur neuropathique, les lésions de la moelle épinière, une lésion cérébrale traumatique, l'accident ischémique cérébral, l'accident vasculaire cérébral, la maladie de Parkinson, le diabète, le syndrome métabolique, les troubles métaboliques, la maladie de Huntington, la maladie de Creutzfeldt-Jakob, l'insomnie fatale familiale, le dyndrome de Gerstmann-Sträussler-Scheinker, et les maladies à prions apparentées, la sclérose latérale amyotrophique, la paralysie supranucléaire progressive, l'infarctus du myocarde, les maladies cardiovasculaires, les inflammations, la fibrose d'organes, les maladies chroniques et aiguës du foie, la stéatose hépatique, la fibrose du foie, les maladies chroniques et aiguës du poumon, la fibrose pulmonaire, les maladies chroniques et aiguës du rein, la fibrose rénale, l'encéphalopathie traumatique chronique (CTE), la neurodégénérescence, les démences, les démences fronto-temporales, les tauopathies, la maladie de Pick, la maladie de Pick-Neimann, l'amyloïdose, une déficience cognitive, l'athérosclérose, les maladies oculaires, les arythmies, dans une transplantation d'organe et dans le transport d'organes pour une transplantation. Par conséquent, l'invention concerne en outre des compositions pharmaceutiques comprenant un composé de l'invention. L'invention concerne par ailleurs des procédés d'inhibition de l'activité de PERK et le traitement de troubles associés à celle-ci au moyen d'un composé de l'invention ou d'une composition pharmaceutique comprenant un composé de l'invention.
Patent CA-3000143-A1 (CA)
Inventor: MASCULL ROGER THOMAS
IPC: A47C7/46
Filed: 2016-09-23
Abstract: A contouring system configured to be modified to provide a support surface, such as a backrest, seat base, or mattress, having contours to suit the needs of its user.
Patent CA-3001792-A1 (CA)
Inventor: PULE MARTIN
IPC: C07K14/55
Filed: 2016-10-21
Abstract: The present invention provides a chimeric receptor which comprises: a ligand-binding exodomain; and an endodomain which comprises: (i) a cytokine receptor endodomain; and (ii) an intracellular T cell signalling domain.
Patent CA-3002096-A1 (CA)
Title: Systemes et procedes de communications de surveillance a distance et hote
Inventor: MAHALINGAM AARTHI
IPC: A61B5/00
Filed: 2016-12-13
Abstract: L'invention concerne des systèmes et des procédés de communication de surveillance à distance et hôte. Dans certains modes de réalisation, les systèmes de surveillance peuvent comprendre un dispositif de surveillance hôte associé à un hôte couplé en termes de communication à un ou plusieurs dispositifs de surveillance à distance associés à des moniteurs distants. Le dispositif de surveillance hôte peut envoyer des communications basées au moins en partie sur des mesures d'analyte d'un détecteur hôte et/ou d'autres données contextuelles donnant ce contexte de mesure. Différents dispositifs de surveillance à distance peuvent recevoir différentes communications basées, au moins en partie, sur le rôle des moniteurs distants respectifs par rapport à l'hôte. Ces rôles peuvent être représentés dans des classifications de moniteurs distants
Patent CA-3002884-A1 (CA)
Inventor: YIN LEI
IPC: C07D401/14
Filed: 2016-11-28
Abstract: The present invention provides compounds as shown in formula I or a tautomer, a mesomer, a racemate, an enantiomer, a diastereomer, a deuterated compound, a prodrug or a mixture thereof, or a pharmaceutically acceptable salt or solvate of the compounds as shown in formula I or a tautomer, a mesomer, a racemate, an enantiomer, a diastereomer, a deuterated compound, a prodrug or a mixture thereof, wherein R1 to R7 are as defined in the description. The present invention also provides a preparation method and a medical use of the compounds. The compounds of the present invention have an activity superior or equivalent to the candidate drug LY2835219 currently under phase III clinical trial, and some of the compounds exhibit better selectivity. Moreover, the preferred compounds exhibit good absorption and good blood-brain distribution when administered orally. The compounds of the present invention thus show promise for development into novel drugs for the treatment of diseases associated with cell proliferation, particularly brain tumors, providing new options for clinicians and patients.
Patent CA-3004902-A1 (CA)
Inventor: FABBRI BRADON JAMES
IPC: A01N63/00
Filed: 2016-11-17
Abstract: Planting corn in one or more consecutive growing seasons in the same fields causes a yield reduction ("corn-on-corn yield penalty"). We developed methods and compositions comprising a lipo-chitooligosaccharide (LCO), to reduce corn-on-corn yield penalty. The disclosure covers the compositions and methods for reducing corn-on-corn yield penalty.
Patent CA-3004979-A1 (CA)
Title: Utilisation de 1,3-diglyceride dans une composition topique pour contrer l'affaiblissement de la barriere cutanee
Inventor: REDOULES DANIEL
IPC: A61K8/37
Filed: 2016-12-08
Abstract: L'invention concerne une composition topique, cosmétique ou dermatologique, comprenant du 1,3-diglycéride de formule générale (I), les radicaux R1 et R2 représentant, indépendamment l'un de l'autre, un radical alkyle linéaire et saturé en C13 à C40, et au moins un excipient cosmétique ou dermatologique pour une application topique sur la peau. L'invention concerne également une telle composition, ou un 1,3-triglycéride de formule (I), destiné à protéger la peau, à contrer l'affaiblissement de la barrière cutanée et à prévenir ou à réduire la pénétration de molécules exogènes dans la peau suite à un affaiblissement de la barrière cutanée.
Patent CA-3011057-A1 (CA)
Inventor: ELLEFSON DEAN C
IPC: B21D51/44
Filed: 2017-01-09
Abstract: A system and method of orienting the rolling direction of metallic objects is provided. More specifically, the present invention relates to systems and methods used to align the rolling direction of metallic objects in a predetermined orientation in a high speed manufacturing system. The rolling direction is determined by sensing grinding marks on the metallic objects. The metallic objects may subsequently be formed by tools that have been adapted to work with, or transverse to, the rolling direction. Optionally, the tools may form the metallic objects into container end closures adapted to seal a container of a predetermined size and type.
Patent CA-3011660-A1 (CA)
Title: Synchronous generator
Inventor: PISKORZ WALDEMAR
IPC: H02K5/04
Filed: 2017-01-18
Abstract: The invention solves the issue of cooling of the power generator by change of its body. According to the invention the generator has a body in the form of open frame structure (1) with polygonal base, made preferably of hollow profiles, connected removably with a clamp (24), where first stator segments (18) are mounted on threaded pins (9), connected removably to the arms (2) of the base and arms (2) of the clamp (24), set on a circle larger than the diameter of a first rotor plate (15) and further rotor plates (22).
Patent CA-3012418-A1 (CA)
Inventor: GATTO FRANCESCO
IPC: G01N33/50
Filed: 2017-03-07
Abstract: La présente invention concerne un procédé de pronostic du cancer à cellules rénales chez un sujet, ledit procédé consistant à déterminer le taux et/ou la composition chimique de l'un ou des deux glycosaminoglycanes (GAG) suivants, à savoir le chondroïtine sulfate (CS) et l'héparane sulfate (HS), dans un échantillon de liquide organique, ledit échantillon ayant été prélevé chez ledit sujet.
Patent CA-3014972-A1 (CA)
Inventor: CHOUINARD REMI
IPC: H01R31/06
Filed: 2018-08-20
Abstract: A cell phone charging station is provided. It is a particular advantage of the cell phone charging station to be positioned at or near eye-level of a user. The cell phone charging station includes a support frame forming part of a body that is attached to a wall at a reasonable height so as to be easily visible and accessible without bending down or reaching up. The support frame has a cell phone compatible socket which connects to a charger. The charger is connected to house current. Preferably, that house current comes from a light switch located next the charging station. The support frame is configured so as to securely hold a cell phone therein.
Patent CA-3017044-A1 (CA)
Title: Biomarker for the diagnosis of pulmonary hypertension (ph)
Inventor: BORDAG NATALIE
IPC: G01N33/68
Filed: 2017-03-08
Abstract: The present invention relates to a method of diagnosing pulmonary hypertension (PH) in a patient, a method of monitoring the course of pulmonary hypertension in a patient, a method of determining the severity of pulmonary hypertension in a patient, and a method of differentiating between pulmonary hypertension and at least one condition selected from a group consisting of a disease associated with a risk of developing pulmonary hypertension and metabolic syndrome. In addition, the present invention relates to a kit comprising means for carrying out the above methods.
Patent CA-3018253-A1 (CA)
Inventor: CHAUDHARY PREET M
IPC: A61K35/17
Filed: 2017-03-31
Abstract: Provided herein are methods for detecting an antigen or for detecting expression of a chimeric antigen receptor (CAR). The methods include obtaining a sample from a subject, contacting the sample with a fusion protein comprising a reporter fused to a single chain antibody specific to the antigen or fused to an extracellular domain of an antigen targeted by the CAR or fused to Protein L and assaying the activity of the reporter, wherein presence of reporter activity or increase in reporter activity relative to a reference value is indicative of presence of the antigen or presence of the expression of the chimeric antigen receptor in the sample.
Patent CA-3019887-A1 (CA)
Title: Procede et appareil d'estimation de variables de traitement de fond de trou de systeme d'ascension au gaz
Inventor: BOIKO IGOR
IPC: E21B43/00
Filed: 2017-03-21
Abstract: L'invention concerne un procédé et un appareil pour estimer une pression d'espace annulaire de fond de trou et/ou une pression de tube de production de fond de trou et/ou un débit de gaz d'ascension de fond de trou par l'intermédiaire d'une soupape d'injection de gaz (6) de système d'ascension au gaz (16), qui comprend au moins une duse d'ascension au gaz (4) et au moins une soupape d'injection de gaz (6) et au moins une duse de production (7). Un estimateur d'état est proposé pour obtenir les valeurs de ces variables de traitement de fond de trou. L'estimateur contient un certain nombre d'estimateurs locaux et un module d'interpolation.
Patent CA-3021040-A1 (CA)
Inventor: VAN VOORHEES SETH
IPC: B32B17/10
Filed: 2017-04-28
Abstract: A light valve comprising: a film having two opposed outer surfaces; a first layer of a polymeric interlayer material upon at least a portion of each opposed outer surface; a first pair of substrates, one adhered to the interlayer material upon the first outer surface of the light valve film and second adhered to the interlayer material upon the second outer surface of the light valve film, these substrates formed from plastic; a second layer of polymeric interlayer material applied to at least a portion of an outer surface of each one of the first pair of substrates; and a second pair of substrates, one adhered to the interlayer upon the outer surface of one of the first pair of substrates and a second adhered to the interlayer material on the outer surface of a second of the first pair of substrates, the second pair of substrates formed from glass.
Patent CA-3021577-A1 (CA)
Title: Method and apparatus for managing thermal runaway gases in a battery system
Inventor: LINDSTROM JEREMY
IPC: H01M10/6566
Filed: 2017-04-20
Abstract: A system comprising one or more battery modules mounted in a rack assembly has a structure which defines a cooling air pathway for flowing cooling air across the side and/or bottom of each battery module thereby cooling the battery module, or alternatively, across the energy calls in the battery module. Further, the system has a structure which defines a thermal runaway gas pathway for flowing thermal runaway gases from a battery module out of the system. The system structure is configured to ensure that the cooling air pathway and thermal runaway gas pathway are physically separated, thereby minimizing the risk of the thermal runaway gas substantially mixing with cooling air thereby potentially resulting in a spontaneous ignition and an explosion.
Patent CA-3022944-A1 (CA)
Title: System and method for displaying search results for a trademark query in an interactive graphical representation
Inventor: ANDERSON STEPHEN C
IPC: G06F16/34
Filed: 2017-05-04
Abstract: In response to a query including a proposed trademark and or more search parameters, a system receives search results, each including at least one ascertainable text-based property and a numeric score indicative of a measure of similarity between the search result and the proposed trademark. To generate an interactive graphical representation of the search results, the system (i) generates a reference indicator for the proposed trademark at a reference location in the interactive graphical representation, (ii) determines, for each of the search results, a first offset along a first axis and a second offset along a second axis relative to the reference location using the numeric score and the at least one ascertainable text-based property of a respective search result, and (iii) generates, for each of the search results, a search result indicator in the interactive graphical representation, in accordance with the determined first and second offsets.
Patent CA-3023189-A1 (CA)
Title: Method of providing insulation to a structure
Inventor: HJELMGAARD THOMAS
IPC: E04B1/74
Filed: 2017-05-11
Abstract: The present invention relates to a method of providing thermal and/or acoustic insulation to a structure, comprising the steps of: - providing a substrate which comprises fibres; - applying the substrate to the structure; - blending the substrate with a binder composition before, during or after application of the substrate to the structure; - allowing curing of the binder composition after the substrate and the binder composition have been applied to the structure; wherein the binder composition comprises at least one hydrocolloid. The present invention also relates to an insulated structure obtainable by said method.
Patent CA-3026274-A1 (CA)
Inventor: SHARMA AVINASH CHANDER
IPC: A61K9/00
Filed: 2017-06-02
Abstract: A nasally administered cannabinoid semi-solid or viscous liquid composition; nasal methods for administering the nasal pharmaceutical compositions; methods for manufacturing the nasal pharmaceutical compositions; and nasal methods of treating diseases treatable by the nasal pharmaceutical compositions formulated with a cannabinoid or mixtures thereof.
Patent CA-3027897-A1 (CA)
Title: Presentation container apparatus
Inventor: FILLION JULIE MARIE FRANCE
IPC: B65D85/36
Filed: 2018-12-18
Abstract: A presentation container comprising a sheet of material comprising a base panel, a wall panel foldably connected to each edge of the base panel, and a lid tab foldably connected to an outer edge of each wall panel, and one or more ribbons attached to the sheet of material. Each wall panel is foldable perpendicular to the base panel such that a side edge of each wall panel is next to each adjacent wall panel, and each lid tab is foldable perpendicular to the associated wall panel to place the container in a constructed form for housing an object in an interior thereof. At least two ends of the ribbons are securable to each other to hold the container in the constructed form, and the container is moveable into a presentation form by unsecuring the at least two ends of the ribbons to display the object.
Patent CA-3028217-A1 (CA)
Inventor: HUI TONY
IPC: H04W4/02
Filed: 2018-12-20
Abstract: A wearable device may monitor one or more parameters of a wearer and enter an emergency state based on the values of the monitored parameters. When in the emergency state, the wearable device may connect to a low-power wide area network and transmit an alert to a remote monitoring location.
Patent CA-3028232-A1 (CA)
Title: Procede permettant d'ameliorer la capacite volumetrique dans des systemes de stockage et de liberation de gaz
Inventor: HOLBROOK BILLY-PAUL M
IPC: F17C11/00
Filed: 2017-06-30
Abstract: La présente invention concerne un monolithe poreux adsorbant le gaz, qui a une capacité de travail gravimétrique et une capacité volumétrique supérieures, un système de stockage de gaz comprenant un monolithe poreux adsorbant le gaz ci-décrit, des procédés de fabrication de ce système et un procédé permettant de stocker un gaz. Le monolithe poreux adsorbant le gaz comporte un matériau adsorbant le gaz et un liant non aqueux.
Patent CA-3028499-A1 (CA)
Title: Method for sending control information, method for receiving control information, network device, and terminal device
Inventor: CHENG YAN
IPC: H04W72/04
Filed: 2017-06-22
Abstract: The present invention provides a method for sending control information. The method includes: determining, by a network device, a resource element group corresponding to a control channel, where the resource element group includes a first resource element for carrying downlink control information and a second resource element for carrying a reference signal, and the reference signal is used to demodulate the downlink control information carried by the resource element group; and sending, by the network device, the downlink control information by using the control channel. In the foregoing solution, a control channel for transmitting a resource element group is provided in a wireless communications system, and the network device may send downlink control information to a terminal device based on the resource elernent group by using the control channel. The resource element group carries the downlink control information and the reference signal for demodulating the downlink control information. This provides a possibility of supporting forward compatibility.
Patent CA-3029472-A1 (CA)
Inventor: CHARRA CYPRIEN
IPC: C07C67/48
Filed: 2017-07-04
Abstract: The invention relates to a method for the depolymerisation of a polyester load comprising opaque PET, said method including at least conditioning, depolymerisation and diol-separation steps, a step of separating the liquid-monomer-rich effluent, and a subsequent discolouration step.
Patent CA-3032395-A1 (CA)
Inventor: O'CONNOR JOHN P
IPC: A61B34/20
Filed: 2017-10-23
Abstract: The present disclosure relates generally to cryosurgery apparatuses and systems for and methods of treatment of distal lung tissue or lesions, and more particularly to guided cryogenic delivery to a distal treatment area within lung tissue via a low-profile, high pressure, closed-tipped catheter or probe configured to pass through a working channel of a bronchoscope and extend to a distal region of the lung.
Patent CA-3035378-A1 (CA)
Title: Carrier-pd-l1 binding agent compositions for treating cancers
Inventor: MARKOVIC SVETOMIR N
IPC: A61K31/00
Filed: 2017-08-31
Abstract: Described herein are compositions of binding agents and carrier proteins, and optionally at least one therapeutic agent, and methods of making and using the same, in particular, as a cancer therapeutic. Also described are lyophilized compositions of binding agents and carrier proteins, and optionally at least one therapeutic agent, and methods of making and using the same, in particular, as a cancer therapeutic. Still also described are methods for treating and/or increasing the therapeutic effectiveness of an immunotherapy of a patient suffering from a cancer which expresses PD-L1 or PD-L2 by administering to the patient a nanoparticle composition and a PD-1 immunotherapy.