baber/WOPTO huggingface dataset:
Patent WO-2019173399-A1 (WO)
Title: Mobile electrocardiogram system
Inventor: SHAH RAKESH
IPC: A61B5/308
Filed: 2019-03-05
Abstract: An electrocardiogram ("ECG") system is provided. The system includes an ECG device capable of receiving ECG signals from a lead system attached to the user. The ECG device then renders the ECG signals into ECG data, and transmits the ECG data to at least one of a user device, such as a smart phone, or a cloud-based storage system. The user device is capable of rendering the ECG data into an ECG graph, and displaying the ECG graph to the user on an application ("app"). The system also provides for a cloud-based storage system capable storing the ECG data and providing access to the ECG data to the user and to medical personal.
Patent WO-2019195798-A1 (WO)
Title: Human pluripotent stem cell derived neurodegenerative disease models on a microfluidic chip
Inventor: SANCES SAMUEL
IPC: G01N27/403
Filed: 2019-04-05
Abstract: Described herein is a microphysiological system for models of disease. Specifically, induced pluripotent stem cells (iPSCs) and iPSC-derived cells, including those obtained from disease patients, are seeded onto microfluidic "chip" devices to study cellular development and disease pathogenesis. Herein, neurodegenerative disease modeling, including Parkinson's Disease (PD) is shown to reproduce key PD pathology in a vascularized human model that contains neurons relating to PD pathology. Such compositions and methods are used for research for PD biomarkers, patient screening for PD risk assessment, and therapeutic discovery and testing. A panel of biomarkers are generated through analysis of living PD-chips by neural activity, whole transcriptomic, proteomic, and metabolomic analysis, and functional enzyme tests of media and tissue. Introducing therapeutics through a vasculature channel, coupled with blood brain barrier penetration studies can be assessed for efficacy in the human neural cells present in the PD-Chip.
Patent WO-2019204807-A1 (WO)
Title: Radiation curable compositions for additive fabrication
Inventor: GOVINDARAJAN SUDHANVA
IPC: B33Y70/00
Filed: 2019-04-22
Abstract: Described herein are thermoset compositions and kits of compositions suitable for use in additive fabrication processes including high concentrations of urethane methacrylate oligomers having at least one polymerizable group, and a number average molecular weight from 750 to 4000 g/mol, an effective quantity of a monofunctional reactive diluent monomer, a defined concentration of a network building agent having a molecular weight that is lower than the urethane methacrylate oligomer, optionally a photoinitiator, and optionally, additives. Also disclosed are methods of creating three-dimensional parts via additive fabrication processes utilizing urethane methacrylate oligomer-centric compositions, wherein various exposure irradiances, cure temperatures, and oxygen content levels are prescribed, as well as the articles cured therefrom.
Patent WO-2020222760-A1 (WO)
Inventor: WANG RUIJIA
IPC: G01V1/46
Filed: 2019-04-29
Abstract: Techniques for calculating and visually presenting multiple acoustic modes that have different formation slowness are disclosed herein. The techniques include methods for receiving time-domain waveforms from adjacent formations in a borehole, processing each of the time-domain waveforms to generate frequency-domain spectrums, selecting frequency and slowness values, and predicting travel time of a mode associated with the slowness value. In some aspects, the method further includes steps for calculating a semblance difference of the frequency-domain spectrums based on the frequency value, the slowness value and the predicted travel time. Systems and computer-readable media are also provided.
Patent WO-2019213214-A1 (WO)
Title: Compounds for treating chronic pain
Inventor: ZADINA JAMES E
IPC: C07K7/64
Filed: 2019-05-01
Abstract: The present application provides a hexapeptide useful in treating pain and opioid use disorder.
Patent WO-2020040833-A1 (WO)
Title: Three-dimensional memory device containing drain-selct-level air gap and methods of making the same
Inventor: NISHIKAWA MASATOSHI
IPC: H01L27/11575
Filed: 2019-05-14
Abstract: A three-dimensional memory device includes an alternating stack of insulating layers and word lines located over a substrate, memory stack structures extending through the alternating stack and containing a respective vertical semiconductor channel and a respective memory film, drain select gate electrodes located over the alternating stack, extending along a first horizontal direction, and laterally spaced apart along a second horizontal direction, and a dielectric cap layer located between adjacent drain select gate electrodes. An air gap is located between adjacent drain select gate electrodes in the dielectric cap layer.
Patent WO-2019226431-A1 (WO)
Title: Production of oligosaccharides
Inventor: JOHNSON MICHAEL BENJAMIN
IPC: C07H1/06
Filed: 2019-05-15
Abstract: A method for producing and purifying human milk oligosaccharides (HMOs) is provided. The method includes fermentation of a genetically modified microbial organism, preferably a genetically modified yeast strain, and downstream processing of the fermentation product using one or more of an enzymatic treatment, filtration, and a simulated moving bed (SMB) chromatography step. Use of the resulting HMO in food or feed applications, preferably in infant food and/or formula is also provided.
Patent WO-2019226841-A1 (WO)
Title: Detection units and methods for detecting a target analyte
Inventor: CELEDON ALFREDO
IPC: C12P19/34
Filed: 2019-05-23
Abstract: The present application relates to detection units and methods for detecting one or more target analytes in a sample using a complex formed by a target and first and second probes, wherein the first probe is coupled to a detectable piece, the target is coupled to the first probe and the second probe, and the second probe is coupled to a solid support. Specific binding of the detectable piece to the target analyte can be distinguished from non-specific binding of the detectable piece by measuring the number of detectable pieces that leave their initial location after exposure to a disruptor that uncouples the detectable piece from the solid support.
Patent WO-2019236515-A1 (WO)
Title: Reconfigurable muffle housings for use in glass manufacturing operations
Inventor: DELIA ROBERT
IPC: C03B17/06
Filed: 2019-06-04
Abstract: Reconfigurable muffle housings and glass manufacturing apparatuses having reconfigurable muffle housings are disclosed herein. In one embodiment, a reconfigurable muffle housing for use in a glass manufacturing apparatus includes a first end portion, a second end portion, and a modular interior portion that is removably and replacably coupled to both the first end portion and the second end portion. The reconfigurable muffle housing has an interior volume for at least partially enclosing a forming device that is configured to produce a glass ribbon.
Patent WO-2020018192-A1 (WO)
Title: Establishment and use of time mapping-based on interpolation using low-mate fingerprinting, to help facilitate frame-accurate content revision
Inventor: DUNKER PETER
IPC: H04N21/8547
Filed: 2019-06-07
Abstract: A computing system identifies multiple matching points between (i) query fingerprints representing a media stream being received by a client and (ii) reference fingerprints, each identified matching point defining a respective match between a query fingerprint timestamped with client time defined according to a clock of the client and a reference fingerprint timestamped with true time defined according to a timeline within a known media stream. Further, the computing system performs linear regression based on the timestamps of the matching points, to establish a mapping between true time and client time. The computing system then uses the mapping to determine a client-time point at winch the client should perform a content revision or other action with respect to the media stream being received by the client. And the computing system causes the client to perform the content revision or other action at the determined client-time point.
Patent WO-2019237124-A1 (WO)
Title: Next generation designer liver organoids and their methods of preparation and use
Inventor: KIANI SAMIRA
IPC: C12N15/867
Filed: 2019-06-10
Abstract: The present disclosure relates to synthetic liver organoids and methods of using such synthetic liver organoids for various applications including drug discovery and modeling human liver development. In particular, provided herein are methods of producing and using synthetic mature liver organoids comprising mature, functional cells found in the human liver.
Patent WO-2020018489-A1 (WO)
Inventor: GETZ JALEM
IPC: G06Q30/06
Filed: 2019-07-16
Abstract: The present invention is a system and method that improves a recommendation system's ability to determine a client's preference in clothing. The system not only receives direct client information though surveys, questionnaires, and client feedback, it also receives input based on a client's visual preferences. Through use of the stream, the client is shown pictures of articles of clothing and rates the articles. Based on the ratings, the system determines a client's visual preference and makes a final recommendation based on the client's visual preferences, which tend to be more accurate and complete than preferences achieved through textual responses.
Patent WO-2020246999-A1 (WO)
Title: Method of producing a glueless dustless composite flooring material system
Inventor: TROENDLE JOHN
IPC: B29C48/16
Filed: 2019-07-23
Abstract: A method of producing a glueless dustless composite flooring material system providing PVC- based flooring having waterproof layers providing different qualities of hardness, wear- resistance, sound deadening, and decorative patterns, avoiding the use of moisture-susceptible compressed cellulose-based filler, with layers fused together, avoiding the manufacturing complexity and del ami nation risks of using glue or adhesive, with a quickly-cured, UV-cured top coating providing long-lasting high performance and shortening and simplifying the manufacturing, which can be done in a sheet-form, essentially continuous-run manner, with an ability to quickly and simply change the optional design printing and texturing produced, and having an optional underlayment layer.
Patent WO-2020028708-A1 (WO)
Title: Electrical stimulation of cells to induce enhanced secretome for therapeutic applications
Inventor: SCHMIDT CHRISTINE E
IPC: C12N5/0775
Filed: 2019-08-01
Abstract: Disclosed herein is a method of treating a subject for a disease, disorder, or condition that involves administering to the subject a composition comprising a secretome derived from electrically stimulated cells. Also disclosed herein is an enhanced secretome produced by a process comprising collecting cells from a subject, culturing the cells in a serum free medium for at least 1 day while stimulating the cells with electric pulses, and collecting the secretome produced by the electrically-stimulated cells. Also disclosed herein is a pharmaceutical composition comprising an enhanced secretome derived from electrically stimulated cells contained within a biocompatible hydrogel in an amount effective to treat a disease or disorder.
Patent WO-2020033349-A1 (WO)
Title: Link status-aware medical devices and gateways
Inventor: VARANASI NANDINI
IPC: G16H40/67
Filed: 2019-08-06
Abstract: Aspects of the subject matter described in this disclosure can be implemented in electronic medical devices, wireless gateway devices, and remote database systems in a network environment where wireless connections are made between at least an electronic device and a wireless gateway device, and between the wireless gateway device or an access point and a remote database system. The electronic medical device, the wireless gateway device, or the remote database system may be configured to identify a data communication loss based on at least a mismatch of a confirmation acknowledgement attribute between two or more nodes in the network environment. Upon identifying the data communication loss, a notification can be provided to an entity such as a user so that data communication can be restored.
Patent WO-2020033429-A1 (WO)
Title: Mobile system for dispensing medication
Inventor: GARG HONEY
IPC: G16H20/13
Filed: 2019-08-06
Abstract: The subject technology provides at least a method of medication management. The subject technology receives, at a mobile device via a network interface, information regarding a medication order from a server. The subject technology sends, with the mobile device via a short range wireless interface, an indication of the medication order to a medication dispensing device, the indication causing the medication dispensing device to provide access to a medication corresponding to the medication order. Further, the subject technology sends, with the mobile device via the network interface, dispense information to the server, the dispense information corresponding to the medication provided by the medication dispensing device.
Patent WO-2020033823-A1 (WO)
Title: Small-molecule pi5p4k alpha/beta inhibitors and methods of treatment using same
Inventor: HA YA
IPC: C07D475/00
Filed: 2019-08-09
Abstract: The present invention relates to the discovery of novel 2-amino-dihydropteridinone compounds and analogues thereof capable of inhibiting phosphatidylinositol phosphate kinases. In certain embodiments, the compounds of the invention can be used to treat p53-null cancer in a subject. In other embodiments, the compounds of the invention can be used to treat metabolic disorders in a subject, including but not limited to type 2 diabetes and/or obesity.
Patent WO-2020242512-A1 (WO)
Title: Concentrated cleaning capsule and dispenser for dispensing cleaning solution therefrom
Inventor: YOUDOVIN DAVID N
IPC: B05B15/30
Filed: 2019-08-29
Abstract: In an example embodiment, a dispenser for dispensing cleaning solution from a capsule is provided. The dispenser comprises a handle, a base, and a dispensing pipette extending from the nozzle into the base. The handle comprises a nozzle, a trigger, a lever, the dispensing pipette, and a capsule chamber. The base comprises a reservoir portion configured for receiving cleaning solution from the capsule. The handle is configured to be secured to the base. When the capsule is positioned within the capsule chamber and the lever is moved from an open position to a closed position, the cleaning solution is provided to the reservoir portion. When the capsule is positioned within the capsule chamber, the handle is secured to the base, and the trigger is activated, the cleaning solution is dispensed from the reservoir portion through the dispensing pipette and out of the nozzle.
Patent WO-2020086188-A1 (WO)
Inventor: BLITZ NEAL
IPC: A61B17/58
Filed: 2019-09-13
Abstract: The present disclosure describes a bone screw for use in orthopedic procedures. The bone screw includes a shank portion having a helical thread and a head portion also having a helical thread. The head portion has a reverse frustoconical shape, with the conical taper decreasing in the proximal direction.
Patent WO-2020081247-A1 (WO)
Title: Potentiated antibiotic compositions and methods of use for treating bacterial infections and biofilms
Inventor: RICE CHARLES V
IPC: A61P31/04
Filed: 2019-10-03
Abstract: Compositions of β-lactam antibiotics and branched poly(ethylenimine) (BPEI), and β- lactam antibiotics and potentiating compounds of polyethylene glycol (PEG)-branched poly(ethylenimine) (BPEI) conjugates, and methods of their use. The BPEI and PEG-BPEI conjugates potentiate the activity of the β-lactam antibiotics so the compositions have synergistic effects against various Gram-positive bacteria. For example, the compositions can be used to treat Gram-positive bacteria, such as Methicillin-resistant Staphylococcus aureus (MRS A), that have developed resistance against most β -lactam antibiotics. The BPEI and PEG-BPEI conjugates result in the resensitization of such resistant bacterial strains to traditional antibiotic therapies such as β -lactam antibiotics. The compositions may also be used in treatments of surfaces and devices and wounds to remove bacterial biofilms.
Patent WO-2020076746-A1 (WO)
Inventor: Siengchum Tritti
IPC: G01N31/00
Filed: 2019-10-08
Abstract: Methods and systems of analyzing and quantifying a surface acidity on a low surface area sample are disclosed. The methods include analyzing a quantity of an effluent molecular probe desorption from a temperature programmed desorption (TPD) process and system, by employing a mass spectroscopy (MS) system. The molecular probe is chemically adsorbed on a clean surface of the sample before the TPD process. The sample has a surface area to mass ratio of less than 5 m 2 /g. In some embodiments, the total surface area analyzed in the method can be as low as 3 m 2 .
Patent WO-2020076907-A1 (WO)
Inventor: TURNER ROBERT
IPC: D04H1/587
Filed: 2019-10-09
Abstract: An absorbent article comprising a first nonwoven material joined to a second nonwoven material by at least one bond area, wherein a polymeric filler composition is disposed within the bond area and the composition comprises at least one polymer selected from the group consisting of polypropylene homopolymers, propylene-ethylene copolymers, and mixtures thereof, wherein the composition is substantially free of tackifiers. It was found that such polymer filler compositions having a Toughness of at least 25 MPa, as measured according to the Extensional Test Method described herein, provide bonds with good resistance to peel creep force.
Patent WO-2020081446-A1 (WO)
Title: Compositions and methods for activating nrf2-dependent gene expression
Inventor: MOELLERING RAYMOND
IPC: C07D333/48
Filed: 2019-10-14
Abstract: Embodiments are directed to a series of novel small molecule activators of NRF2 dependent gene expression that are evaluated in an effort to develop therapeutic methods against diseases with deregulated KEAP1-NRF2 signaling.
Patent WO-2021076100-A1 (WO)
Title: Flexible coating composition
Inventor: TYE ANTHONY
IPC: C08G18/42
Filed: 2019-10-15
Abstract: The present disclosure describes polymers and improved resin systems having flexibility, low water uptake, good adhesion, chemical resistance, and/or weatherability at extreme negative temperatures, such as temperatures down to about -40°C or below and even temperatures down to about -60°C. The systems herein, in approaches, include a polymer or resin system for an epoxy component of an epoxy/amine system including an epoxy and/or acetoacetoxy functionalized flexible block copolymer that has a base hydrophobic polyol block or core, optional flexible monomeric blocks, and epoxy, acetoacetoxy, or both functional endcaps.
Patent WO-2021076125-A1 (WO)
Inventor: LIN QIAN
IPC: G06N20/20
Filed: 2019-10-16
Abstract: Examples of methods for training using rendered images are described herein. In some examples, a method may include, for a set of iterations, randomly positioning a three-dimensional (3D) object model in a virtual space with random textures. In some examples, the method may include, for the set of iterations, rendering a two-dimensional (2D) image of the 3D object model in the virtual space and a corresponding annotation image. In some examples, the method may include training a machine learning model using the rendered 2D images and corresponding annotation images.
Patent WO-2020092949-A1 (WO)
Inventor: KUCERA DAVID
IPC: F23N5/24
Filed: 2019-11-01
Abstract: Un système d'analyse de flamme qui peut incorporer un brûleur, un ou plusieurs capteurs au niveau du brûleur, une base de données d'historique connectée audit au moins un capteur, un module d'apprentissage de modèle connecté à la base de données d'historique, et un module d'algorithme d'exécution connecté audit au moins un capteur et au module d'apprentissage de modèle. L'algorithme d'exécution peut comparer des données en temps réel provenant dudit au moins un capteur et des données d'historique provenant du module d'apprentissage de modèle conformément à un algorithme d'apprentissage automatique. Le système peut en outre incorporer un module de détection de défaillance connecté au module d'algorithme d'exécution, un module de diagnostic de défaillance connecté au module de détection de défaillance, et un dispositif d'énonciation connecté au module de détection de défaillance . Le ou les capteurs peuvent également comprendre une sensibilité vidéo ou acoustique de la combustion dans le brûleur.
Patent WO-2020102366-A1 (WO)
Title: Methods of determining the risk of bovine respiratory disease in pre-weaned dairy calves
Inventor: ALY SHARIF
IPC: C12Q1/70
Filed: 2019-11-13
Abstract: Provided are methods of determining the risk of bovine respiratory disease (BRD) in pre-weaned dairy calves on a dairy farm. In certain aspects, the methods include extracting dairy farm management practice information from a dairy farm, wherein the dairy farm management practice information comprises one or more items of information for two or more dairy farm management practice categories selected from the group consisting of: basic herd risk profile, maternity pen management, colostrum management, milk feeding, vaccinations, and calf housing. In certain aspects, the methods further include assigning weighted risk scores to the items of dairy farm management practice information extracted, and determining a total risk score for each of the two or more dairy farm management practice categories based on the assigned weighted risk scores. Also provided are non-transitory computer-readable media and computer devices that find use, e.g., in practicing the methods of the present disclosure.
Patent WO-2020102811-A1 (WO)
Title: Training apparatus for use in water
Inventor: TAMPOYA CHRISTOPHER ALAN
IPC: A63B59/58
Filed: 2019-11-18
Abstract: An underwater training apparatus is disclosed. The underwater training apparatus may include a barrel. The barrel may contain a plurality of holes disposed across the barrel. Each of the holes of the barrel may pass through a wall of the barrel. The underwater training apparatus may also include a base funnel. The base funnel may contain a plurality of holes disposed across the base funnel. Each of the holes of the base funnel may pass through a wall of the base funnel. The underwater training apparatus may also include a handle. The handle may mechanically couple the barrel and the base funnel.
Patent WO-2020113085-A1 (WO)
Inventor: MCKENDALL THEODORE
IPC: H04L29/06
Filed: 2019-11-27
Abstract: A protector server located in the Web traffic between an end-user computer and a Web site intercepts requests for Web pages from the Web site. The server inserts protection code into a Web page returned to the user computer which executes within the user browser. The code disables malware executing within the user browser by establishing itself as an event handler, finding likely malware in the stack, and disabling it. The code thwarts host-based malware by establishing itself as an event handler, and encrypting data fields of forms before the form is submitting to the operating system of the user computer. The code detects a Web inject attack by calculating a fingerprint for a form on the Web page and sending that fingerprint to the server. The server compares that fingerprint with one previously calculated for the form and generates an alert if different. The code detects a phishing attack by sending a notification to the server indicating within which domain it is executing. The server generates an alert if the received domain is different from an expected domain. The server provides a Web application firewall.