baber/WOPTO huggingface dataset:
Patent EP-0830141-B1 (EP)
Inventor: SMITH GALE EUGENE
IPC: A61K39/245
Filed: 1996-04-26
Granted: 2003-06-25
Abstract: Improved mammalian virus vaccines are combinations that contain an immunogenic amount of inactivated virus, such as influenza virus, Herpes varicella virus, measles virus, Epstein Barr virus, respiratory syncytial virus, parainfluenza 3, Herpes simplex type 1 virus, and Herpes simplex type 2 virus, and an immunogenic amount of a purified recombinant envelope protein from the virus, or a fragment or precursor of the protein. Alternatively, they contain either inactivated virus and/or envelope protein antigens and an adjuvant such as granulocyte-microphage colony stimulating factor. One embodiment of an influenza vaccine is prepared by combining inactivated virus, preferably three strains of the virus, and hemagglutinin, preferably a combination of respective hemagglutinins for each of the three strains present. In another embodiment, an influenza vaccine is prepared by combining inactivated virus, again preferably three strains of the virus, and neuraminidase, preferably a combination of respective neuraminidase for each of the three strains present. In a third embodiment, the vaccine contains inactivated virus and both hemagglutinin and neuraminidase, preferably using three strains of each. Granulocyte-macrophage colony stimulating factor is, optionally, added to these embodiments.
Patent EP-0776535-B1 (EP)
Inventor: ADAMS ALFRED RODNEY
IPC: H01S5/34
Filed: 1996-05-28
Granted: 2001-10-24
Abstract: L'invention se rapporte à un laser ayant une couche active (M)QW (=à puits quantique(s) (multiples)) (2), où une partie (2A) du puits quantique (2A) et les couches d'arrêt (2B, 2C) ont une contrainte de compression tandis qu'une autre partie (2B, 2C) a quant à elle une contrainte de traction dirigée dans le sens opposé. On dose ces contraintes dans un laser classique de sorte qu'elles se compensent mutuellement et qu'il n'en résulte sensiblement aucune contrainte nette pour le laser, si bien que les contraintes constitutives peuvent être relativement élevées sans que le phénomène de contrainte n'entraîne de graves défectuosités dans le laser. Toutefois, le laser classique a un inconvénient; un phénomène de dégradation prématurée se produit lorsque la longueur d'ondes d'émission est faible (par exemple, inférieure à 0,7 νm) et que la puissance est élevée. Le laser décrit dans l'invention offre l'avantage d'une surcompensation desdites contraintes, si bien que la contrainte nette est une contrainte de traction. D'une part, les avantages de la compensation sont suffisamment bien exploités, et d'autre part, on bénéficie d'un avantage surprenant du fait que le rayonnement produit est absorbé dans une moindre mesure à proximité des faces d'extrémité (30) du laser. Il en résulte donc un phénomène considérablement réduit de dégradation dite de faces terminales ou de miroir. En conséquence, ce laser a une durée de vie allongée par rapport à un laser classique. Le principe reconnu dans l'invention est que la relaxation de contrainte se traduit par une augmentation de la bande interdite adjacente aux faces terminales (30): d'où une diminution de l'absorption du rayonnement. On décrit par ailleurs un procédé de fabrication du laser en question. De préférence, le laser considéré comporte une ou plusieurs couches de puits quantique(s) (2A) ayant une contrainte de compression, et un certain nombre de couches d'arrêt (2B, 2C) ayant une contrainte de traction excédentaire. On tire le meilleur parti de l'invention dans la fabrication du laser à courtes longueurs d'ondes, par exemple dans un système à matériau de type GaAs/InGaP/InAlGaP.
Patent EP-0839205-B1 (EP)
Inventor: SANDIG VOLKER
IPC: C12N15/86
Filed: 1996-07-08
Granted: 2000-02-02
Abstract: PCT No. PCT/DE96/01253 Sec. 371 Date Apr. 23, 1998 Sec. 102(e) Date Apr. 23, 1998 PCT Filed Jul. 8, 1996 PCT Pub. No. WO97/04117 PCT Pub. Date Feb. 6, 1997The invention concerns an adenovirus vector for liver specific gene therapy; fields of application in medicine are the treatment of gene defects and tumour diseases of the liver and molecular biology. The vector according to the invention is marked by the fact that a therapeutic gene is coupled with a liver-specific promoter consisting of enhancer elements of the hepatitis B virus and an enhancerless minimum promoter and is optionally surrounded by SAR elements wherein the promoter is inserted into the adenovirus genome.
Patent EP-0799493-B1 (EP)
Inventor: CLAASSEN WILHELMUS C M
IPC: H01J61/36
Filed: 1996-10-10
Granted: 2002-08-07
Abstract: Lampe électrique possédant une ampoule (1) dans laquelle loge un élément électrique (3) relié à des conducteurs (4) prenant leur source dans l'ampoule. Au moins un de ces conducteurs (4) présente une longueur partielle (5) qui est une fusion solidifiée et dans la zone de laquelle le conducteur (4) forme un coude. De ce fait, l'élément électrique (3) est aligné dans l'ampoule (1). On peut fabriquer la lampe en effectuant la fusion du conducteur (4) au moyen d'un laser, par exemple, dans la lampe finie.
Patent EP-0858653-B1 (EP)
Inventor: HAAVISTO PETRI
IPC: G10L19/00
Filed: 1996-10-30
Granted: 2002-02-13
Abstract: PCT No. PCT/FI96/00578 Sec. 371 Date Oct. 9, 1998 Sec. 102(e) Date Oct. 9, 1998 PCT Filed Oct. 30, 1996 PCT Pub. No. WO97/16819 PCT Pub. Date May 9, 1997A codec is introduced, according to a new speech encoding method, into a speech transmitting transceiver of a digital telecommunications system in order to use a "new" codec and an "old" codec in parallel in the system. A codec is selected by implementing a handshaking procedure between transceivers, handshaking, where a speech encoding method implemented in all transceivers and previously used in the telecommunications system concerned, is used at the beginning of each connection. At the beginning of a phone call and after handover, the method checks whether both parties can also use the new speech encoding. The handshaking messages have been selected so that their effect on the quality of speech is minimal, and yet so that the probability of identifying the messages is maximal.
Patent EP-0885321-B1 (EP)
Inventor: MAURER GUENTER
IPC: A24D3/10
Filed: 1996-12-18
Granted: 2000-05-10
Abstract: The disclosure relates to a melt-blown non-woven fabric based on cellulose esters, with fibers of mean diameter less than about 10 microns. The fabric contains 0-10 wt. % extractable softener, has a reflection factor determined according to DIN 53 145 Part I (1992) of more than 60% and the cellulose ester has a degree of substitution DS of about 1.5-3.0. The softener is preferably water-extractable. A melt-blown non-woven fabric is produced with the cellulose ester as follows: a cellulose ester, cellulose acetate, with a DS of about 1.5-3.0, in particular 1.7-2.7, is mixed with softener in a weight ratio of about 2:1 to 1:4 and simultaneously heated and melted. The mixture of softener and cellulose ester has a melting index MFI (210/2.16) according to DIN 53 735 of about 400 to 5 g/10 min., in particular 300 to 50 g/10 min. The melt is worked in a melt-blown spinning device into a melt-blown non-woven fabric and the softener is then extracted with a softener solvent to leave a proportion of 0-10 wt. %. The melt-blown non-woven fabric is especially suitable as a filter material.
Patent EP-0814331-B1 (EP)
Inventor: PRIKRYL IVAN
IPC: G01B9/02
Filed: 1996-03-19
Granted: 2001-05-16
Abstract: An interferometer includes a beamsplitter for splitting a source beam into a test beam and a reference beam, an imaging device for detecting an interference pattern, a mirror disposed in a path of the test beam for reflection of the test beam toward the imaging device, a micromirror disposed in a path of the reference beam for reflection of a portion of the reference beam toward the imaging device, and a focusing mechanism disposed for focusing the reference beam on the micromirror. The micromirror has a lateral dimension not exceeding the approximate lateral dimension of a central lobe of the reference beam focused thereon by the focusing mechanism. A spatial filter for reducing effects of aberration in a beam includes a reflector disposed upon a transparent base wherein the reflector has a lateral dimension not exceeding the approximate lateral dimension of a central lobe of the spatial intensity distribution of the beam focused upon the reflector. A method of filtering a beam in a wavefront measurement system is also provided. This method includes focusing the beam, reflecting a particular first portion of the focused beam, and transmitting a second portion of the beam. <IMAGE>
Patent EP-0854425-B1 (EP)
Inventor: KRUSCHINSKI MARCUS
IPC: G06F5/06
Filed: 1997-11-08
Granted: 2002-09-04
Abstract: The protection is obtained with a ring memory buffer Ä3Ü within a read /write memory Ä39Ü that has a number of cells. A cyclic pointer counter is formed with a microprocessor Ä30Ü based unit that determines where the data is stored in memory by controlling the pointer. The processor operates to a control program Ä38Ü.
Patent EP-0791686-B1 (EP)
Inventor: KOSKINEN JUKKA
IPC: D21H23/50
Filed: 1997-02-18
Granted: 2002-04-10
Abstract: The invention relates to an assembly for preventing plugging of a narrow, slot-orifice-type jet nozzle 6 used in a paper and board coater in which jet nozzle extends over the entire cross-machine width of the web being coated, said coater comprising an application chamber (11), a coating mix infeed channel (10) connected thereto and a slot orifice (6) as well as at least one infeed port for feeding the coating mix into said application chamber (11). According to the invention, an easily cleanable strainer element (12) is placed close to the applicator apparatus, said strainer serving to separate aggregates of the coating mix that otherwise could plug the slot orifice (6). <IMAGE>
Patent EP-0794336-B1 (EP)
Inventor: SCHIEFER ERWIN
IPC: E21D20/02
Filed: 1997-01-15
Granted: 1999-04-21
Abstract: The tie-rod (1) has a bracing part (4) fitting into a hole, and a threaded profile (5) cooperating with an organic and or inorganic compound filler in the hole. The threaded profile is in the form of a coarse thread with thread-pitch (s) diminishing constantly or in steps from the front end (6) of the tie-rod to the back part (2). The thread pitch of the coarse thread is nil in the part (43)next to the back part. The coarse thread has a radial thread depth (t) diminishing constantly or in steps from the front end to the back. The front end is joined to the top part (7) which has a wedge-shaped point (8).
Patent EP-0874744-B1 (EP)
Inventor: BAUER HERMANN
IPC: B60R21/26
Filed: 1997-01-10
Granted: 2000-10-18
Abstract: L'invention concerne un générateur de gaz servant à produire un mélange de gaz à partir d'un gaz de réserve et d'un gaz propulseur. Ledit générateur comporte une chambre de réserve, de préférence de forme cylindrique et allongée, dans laquelle se trouve le gaz de réserve, qui est à peu près à la température ambiante, et dont l'orifice d'écoulement est fermé, lorsque le générateur est à l'état non activé, par un dispositif à éclatement. Dans une chambre de combustion entourée par la chambre de réserve et servant à la production, de préférence pyrotechnique, du gaz propulseur chaud, lequel peut s'écouler dans la chambre de réserve en passant par des orifices de sortie. Lesdits orifices de sortie sont placés à distance de l'orifice d'écoulement, en particulier sur un côté opposé à l'orifice d'écoulement, à l'intérieur du générateur de gaz, tout en n'étant pas étanche au gaz de réserve sous pression se trouvant dans la chambre de réserve. Ce générateur de gaz est constitué d'un nombre de composants aussi petit que possible. La disposition de la chambre de réserve et de la chambre de combustion garantit un mélange aussi régulier que possible du gaz de réserve et du gaz propulseur et une augmentation aussi régulière que possible de la pression intérieure de la chambre de réserve.
Patent EP-0886737-B1 (EP)
Inventor: DARBY C PETER
IPC: B01D35/31
Filed: 1997-03-12
Granted: 2003-04-23
Abstract: Pressure vessels having end closures for sealing at least one open end are constructed so as to provide full-bore access to a generally tubular shell portion wherein one or more filter cartridges will be disposed. A sealing ring (45) of rectangular cross section is seated in a groove provided in the tubular shell (15) at a location axially inward of a cylindrical surface region wherein a central annular groove is provided. A closure head (39) fits within this annular surface and includes a shoulder (73) which prevents insertion past the sealing ring (45). The head may be a 2-piece construction wherein a flanged and dished element having an inward facing convex surface of oblate spheroidal shape protrudes through the interior of the sealing ring and mates with a securing plate (41) having an annular notch in the periphery of its outer face that aligns with the groove in the tubular shell to create a pocket designed to receive a helical locking ring (79) in the form of a spring-like band of at least two revolutions that cannot be inadvertently removed when the vessel is pressurized. A bell-end configuration for the tubular shell is efficiently created from filament-reinforced polymeric resin through the use of a sacrificial insert that not only creates the seat for the sealing ring but also provides space to accommodate side flow fluid connections.
Patent EP-0898571-B1 (EP)
Inventor: VERNER ERIK JOEL
IPC: C07D495/04
Filed: 1997-04-09
Granted: 2003-11-19
Abstract: Methods, compositions, and compounds for modulating the activity of an endothelin peptide are provided. The methods use compositions that contain compounds that include those of the formula:   <IMAGE> include O, S, and NH; Y is selected from O+ and N, and R1 and R2 are each selected independently from among alkyl, lower alkenyl, lower alkynyl, lower haloalkyl, halide, pseudohalide or H, except that R2 is not halide. R3, R4 and R5 are selected from among groups that include hydrogen, halide, alkoxy, alkyl, haloalkyl; and R7 is selected from groups that include (CH2)rR18, in which r is 0 to 6 and R18 is selected from groups that include aryl, particularly pyrmidinyl and phenyl. The methods are effected by contacting endothelin receptors with one or more of the compounds or with compositions containing one or more of the compounds prior to, simultaneously with, or subsequent to contacting the receptors with an endothelin peptide.
Patent EP-0898767-B1 (EP)
Inventor: JAIN RAJIV
IPC: G06T19/20
Filed: 1997-06-18
Granted: 1999-12-15
Abstract: A computer method draws overlapped two-dimensional shapes and two-dimensional projections of three-dimensional shapes onto a projection plane in a system of world coordinates X,Y,Z. The method instantiates a plurality of two-dimensional geometry class objects, each of which includes an order attribute specifying an overlapped position for depicting a corresponding two-dimensional shape on a projection plane positioned orthogonally to the Z coordinate of the world coordinate system. The method instantiates a three-dimensional geometry class object including a Z-value for a position along the Z world coordinate of the three-dimensional shape. The method sorts the plurality of two-dimensional geometry class objects by their respective order attributes in a sorting table in the memory. The method sorts the three-dimensional geometry class object by its Z-value in the sorting table and orders it in a composite order with the two-dimensional class objects in the sorting table. The method then draws the two-dimensional shapes and two-dimensional projections of the three-dimensional shapes onto the projection plane in the composite order of the sorting table, to depict an overlapped appearance of the shapes.
Patent EP-0914171-B1 (EP)
Inventor: ANTAKI JAMES F
IPC: A61M60/812
Filed: 1997-06-26
Granted: 2001-10-17
Abstract: A rotary pump for pumping fluid through a patient comprises:     (a) a housing (324) (b) a stator member (320) attached to said housing (324) and having a first portion, a second portion, and a plurality of stationary blades (334) attached to said stator member (320) at said first portion thereof, wherein said stator member is generally axially symmetric having a substantially conical-shaped tail and a substantially conical-shaped nose; (c) an impeller (322) positioned within said housing and having an exterior wall, an interior wall forming a void, a plurality of outboard blades (360) extending outwardly from said exterior wall, and a plurality of inboard blades (372) extending inwardly from said interior wall, wherein said stator member second portion extends within said interior wall of said impeller, and wherein said inboard impeller blades (372) are concave or convex (longitudinal curve) such that the curvature thereof corresponds with the curvature of said stator member (320); (d) means for levitating said impeller (322) which centres said impeller within said housing (324); and (e) means for rotating said impeller (322) which exerts and force on said plurality of impeller blades (372) to rotate said impeller.   The impeller preferably has an ellipsoidal configuration. <IMAGE>
Patent EP-0915899-B1 (EP)
Inventor: LIU JIH-HUA
IPC: A61P31/04
Filed: 1997-07-28
Granted: 2004-08-04
Abstract: Preparation of 6-O-methylerythromycin A crystal form II comprising: (a) converting erythromycin A to 6-O-methylerythromycin A; (b) treating 6-O-methylerythromycin A with a solvent selected from (i) an 1-5C alkanol (except ethanol or isopropanol), (ii) a 5-12C hydrocarbon, (iii) a 3-12C ketone, (iv) a 3-12C carboxylic ester (except isopropyl acetate), (v) a 4-10C ether, (vi) benzene (optionally substituted by one or more substituents selected from 1-4C alkyl, 1-4C alkoxy, nitro or halo), (vii) a polar aprotic solvent, (viii) a compound of formula HNR1R2 where R1, R2 = H or 1-4C alkyl (provided that R1 and R2 are not both H), (ix) water and a water miscible solvent selected from a water miscible organic solvent and a water miscible alkanol, (x) methanol and a second solvent selected from a 5-12C hydrocarbon, a 2-5C alkanol, a 3-12C ketone, a 3-12C carboxylic ester, a 4-10C ether, benzene (optionally substituted by one or more substituents selected from 1-4C alkyl, 1-4C alkoxy, nitro or halo), (xi) a 5-12C hydrocarbon, a 3-12C carboxylic ester, a 4-10C ether of from 4 to 10 carbon atoms, benzene (optionally substituted by one or more substituents selected from 1-4C alkyl, 1-4C alkoxy, nitro or halo), and a polar aprotic solvent; and (c) isolating the 6-O-methylerythromycin A form II crystals.
Patent EP-0890223-B1 (EP)
Inventor: JAERVELAE MIKKO
IPC: H04B7/10
Filed: 1997-12-19
Granted: 2004-03-03
Abstract: The present invention relates to a method for allocating RAKE branches and a RAKE receiver. The solution is used in a radio system where a transmitter transmits a signal to a receiver comprising RAKE branches which receive the signal at different polarization levels. The RAKE branches are allocated to receive the signal on the basis of an impulse response, and in which method the impulse responses of the signals received at different polarization levels are weighted by values describing signal quality for optimizing allocation.
Patent EP-0934746-B1 (EP)
Inventor: VOROZHTSOV GEORGY NIKOLAEVICH
IPC: A61K9/08
Filed: 1997-12-03
Granted: 2003-10-22
Abstract: The present invention relates to a substance in the form of an aqueous extract of vegetal raw material which is used for treating oncological diseases, as well as a method for producing said substance. The substance comprises the aqueous extracts of plants from the genus Geranium and Plantago as well as from the species Calendula officinialis, wherein said extracts are obtained from the following amounts in grams of said plants and water : from 10 to 60 of dried Geranium or from 300 to 360 of fresh Geranium ; from 10 to 60 of dried Plantago ; from 10 to 60 of dried Calendula officinialis : and 300 grams of water. This substance may also contain an extract of a plant from the species Pentaphilloides fruticosa obtained from an amount of 10 to 60 grams of dried plant as well as an extract of a plant from the genus Angelica obtained from an amount of 10 to 60 grams of dried plant. The method for producing said aqueous extracts comprises macerating the plants in water before press-filtering the mixture and submitting it to a centrifugal treatment. This substance may be used in oncological practice as part of a cancer therapeutic program.
Patent EP-0947047-B1 (EP)
Inventor: WILLIAMS NORMAN
IPC: H01L21/302
Filed: 1997-12-19
Granted: 2002-04-03
Abstract: An arrangement and method for matching a load and a power source, such as an r.f. power source for a vacuum plasma processing chamber, includes a match network coupled between the power source and the load. The match network has at least two controllably variable electrical characteristics. A sensor is provided that senses at least two parameters of the load. A drive controller responds to the sensed parameters of the load to independently control varying a first one of the electrical characteristics of the match network as a function of only one of the parameters of the load, and a second one of the electrical characteristics of the match network as a function of another one of the parameters of the load. This is done until the power source and the load are in a matched condition. The separation of the match variables to establish a nearly one-to-one correspondence with the load parameters allows independent adjustment of the match variables to provide fast and unambiguous reaching of the matched condition.
Patent EP-0877252-B1 (EP)
Inventor: LELAND JOHN K
IPC: C12Q1/68
Filed: 1992-02-05
Granted: 2007-01-10
Abstract: The invention relates to an apparatus for performing a binding assay for an analyte of interest in a sample based upon measurement of electro-chemiluminescence at an electrode surface comprising an electrochemical cell having a sample-holding volume, inlet and outlet means; a working electrode system to provide electrochemical energy to trigger electrochemiluminescence; a voltage control device to supply voltage signals to the working electrode system; a magnet placed in proper orientation and in close proximity to the working electrode so that magnetically responsive particles will concentrate on the surface of the working electrode; a light detection/measurement device for measuring electrochemiluminescence triggered at the electrode surface; and a pump to provide for fluid transport to, through and from the electrochemical cell. The apparatus may be used in an electrochemiluminescence assay for an analyte of interest in which magnetically responsive particles are magnetically collected on the electrode surface and emitted electrochemiluminescence is measured using the light detector. <IMAGE>
Patent EP-0861596-B1 (EP)
Inventor: BRADBURY ALLAN GEORGE WILLIAM
IPC: A23F5/24
Filed: 1998-01-12
Granted: 2004-03-31
Abstract: The present invention is directed to a liquid coffee in which the development of acidity has been inhibited and which results in a longer shelf-stable product. The method used in making the liquid coffee product of the present invention comprises treating the coffee extract with an alkali, said alkali being present in an amount effective to convert acid precursors present in the coffee extract to their respective acid salts, and thereafter neutralizing the treated coffee extract with an acid, said acid being present in an amount effective to neutralize any excess alkali from the first step and to adjust the final pH of the liquid coffee product to the desired value.