baber/WOPTO huggingface dataset:
Patent CA-3156484-A1 (CA)
Title: Pharmaceutical drug containing heterocyclidene acetamide derivative
Inventor: TARUI TAKESHI
IPC: A61P43/00
Filed: 2020-10-02
Abstract: This disclosure provides a means for treating dry eye. This disclosure can provide: a composition for treating dry eye; and a use thereof. The composition includes (E) -2-(7-trifluoromethyl-chroman-4-yllidene)-N-(7-hydroxy-5,6,7,8-tetrahydronaphthalene-1-yl)acetamide, a pharmaceutically acceptable salt thereof, or a solvate thereof. This disclosure can provide: a composition for treating dry eye; and a use thereof. The composition includes a Vi/Vc zone inhibitor.
Patent CA-3157160-A1 (CA)
Title: Patient-specific instrumentation and methods for ankle arthroplasty
Inventor: KHATIBI BAHAREH
IPC: A61F2/46
Filed: 2020-10-16
Abstract: Patient-specific guide systems and methods for performing bone resections for ankle arthroplasties comprises a bone guide body and a bone resection block. The bone guide body comprises a patient-specific surface for engaging a surface of a talus or a tibia, and a first pin hole and a first socket in the bone guide body. The bone resection block is removably insertable into the first socket, receives a first pin that can be inserted in the first pin hole, and includes a resection guide surface. The system further comprises a floating bone trial that attaches to the bone resection block via a floating bone guide. The floating bone trail receives a chamfer spacer and guide for further resecting the bone. The system further comprises a stylus for engagement with the resection guide surface to confirm resection depth. The bone guide body includes alignment pin and resection block snap lock features.
Patent CA-3158523-A1 (CA)
Inventor: CAO SHANGWEN
IPC: G06F30/10
Filed: 2020-09-08
Abstract: This invention presents a method and a system that use rendering facets to conduct hybrid geometric modeling for three dimensional product design, wherein a geometry operation comprises the steps: mapping rendering facets to operating facets, creating intersection lines, splitting each triangle through which an intersection line passes, sectioning geometries, regrouping facets to form new geometric objects, and mapping each new geometric object to rendering facets. To record modeling process, the method has the steps: allocating a Constructive Hybrid Geometry object, making up each Operating Geometry including a geometry object and operational parameters, adding an Operating Geometry to the object, conducting operations with the facets, and updating operational results. The system is flexible and able to create fine and variant geometric models with primary geometric objects, extended geometric objects and surface patches.
Patent CA-3159979-A1 (CA)
Inventor: KIM YEONCHUL
IPC: C07K14/475
Filed: 2020-12-10
Abstract: Disclosed are: a fusion polypeptide comprising growth differentiation factor 15 (GDF15) and a polypeptide region capable of O-glycosylation; a pharmaceutical composition comprising the fusion polypeptide; and a method for increasing the in vivo duration of GDF15, comprising the step of fusing a polypeptide region capable of O-glycosylation.
Patent CA-3160535-A1 (CA)
Inventor: MULLER RALF
IPC: G01N21/64
Filed: 2020-12-04
Abstract: The invention relates to an arrangement for operating a biosensor (01) emitting radiation. The arrangement comprises an excitation light source (03), which generates at least one excitation radiation for the biosensor; a coupling fiber (04), at the entry surface of which the excitation radiation is coupled in; an optical Y-coupler (12), including an excitation arm (11), which is connected to the exit surface of the coupling fiber (04), a detector arm (13), which is connected to an optical detector (21), and a sensor foot (14), which can be connected to the biosensor (01). The excitation arm (11) has a conical shape. The radiation axis of the excitation arm (11) includes an angle in the range of 5° to 70° with the main radiation axis of the detector arm (13). The diameter of the excitation arm (11) at the connecting point (16) to the detector arm is less than two thirds the diameter of the detector arm (13). The invention furthermore relates to an arrangement for determining the glucose content, in particular of blood.
Patent CA-3164826-A1 (CA)
Title: Multifunctional aminoquinoline therapeutic agents
Inventor: TABAKOFF BORIS
IPC: A61K33/243
Filed: 2015-06-18
Abstract: Aminoquinoline compounds useful for treating chronic pain, addiction, and other conditions are provided. The aminoquinoline compound is represented by Formula (I): (see formula I)
Patent CA-3165651-A1 (CA)
Title: Multi-layer backup ring
Inventor: DENG GUIJUN
IPC: E21B23/01
Filed: 2021-01-19
Abstract: A backup ring assembly has a plurality of radially offset ring members including an outermost ring member formed from plurality of axially extending segments. Each of the plurality of axially extending segments includes an outer surface. A first interlock member support is coupled to the outer surface of one of the plurality of axially extending segments of the outer most ring member. A second interlock member support is coupled to the outer surface of an another one of the plurality of axially extending segments of the outermost ring member. An interlock member includes a first end supported at the first interlock member support and a second end supported at the second interlock member support. The interlock member restrains radially outward expansion of the ring and circumferential expansion of a gap extending between the one of the axially extending segments and the another one of the axially extending segments.
Patent CA-3167677-A1 (CA)
Inventor: FOX MICHAEL
IPC: G21C19/02
Filed: 2022-07-14
Abstract: This invention provides an improved method to modify the input drives of a PHWR fueling machine to ensure their operability so to minimize the potential of a fueling machine becoming stuck on a nuclear reactor fuel channel. During the life cycle of a PHWR fueling machine it is possible for the fueling machine input drives bearings to become damaged or seized due to particulate, magnetite, and CRUD (chalk river unidentified deposit) build up on the bearings. These deposits can cause the fueling machine to become stuck on a reactor fuel channel necessitating a reactor shut down to remove the fueling machine. A modification to the input drive assemblies to allow for the installation of bearing holders, sleeve bearings, mechanical fuse and a modified labyrinth seal holder to allow for the ability to recover the fueling machine from the nuclear reactor fuel channel in the event of seized bearings.
Patent CA-3167752-A1 (CA)
Title: Conductance electronique dans des dispositifs et des systemes bioelectroniques
Inventor: LINDSAY STUART
IPC: G01N27/30
Filed: 2021-02-11
Abstract: La présente divulgation concerne des dispositifs, des systèmes et des procédés associés à la bioélectronique protéique. Plus particulièrement, la présente divulgation concerne des dispositifs, des systèmes, et des procédés bioélectroniques qui utilisent un potentiel électrique défini pour optimiser la conductance électrique d'une protéine d'intérêt, pouvant servir de base pour la fabrication de dispositifs bioélectroniques améliorés destinés à une mesure directe de l'activité des protéines.
Patent CA-3168468-A1 (CA)
Title: Methane separation system and method
Inventor: MANN CHRISTOPHER MARK
IPC: F17C1/00
Filed: 2021-01-29
Abstract: Systems and methods for separating a biogas or other gaseous material into its constituent parts, including solid methane and carbon dioxide, using liquid nitrogen in a processing chamber. The individual parts may be extracted from the processing chamber. Separation and extraction can be performed on a mobile processing plant.
Patent CA-3170328-A1 (CA)
Title: Polymer dispersion having improved adhesion and wettability and methods for the same
Inventor: STEVENS BART
IPC: C09D5/14
Filed: 2022-08-12
Abstract: An antimicrobial coating composition is disclosed. The antimicrobial coating composition also includes a polymer having a plurality of alkene units and a plurality of macroCTA polymer units. The composition also includes one or more reactive silanes, one or more wetting agents, and one or more solvents. A method for applying an antimicrobial coating composition is disclosed.  The method for applying an antimicrobial coating composition may include contacting a polymer, one or more wetting agents, one or more solvents, and one or more reactive silanes with one another to prepare an antimicrobial coating composition, homogenizing the antimicrobial coating composition, applying the antimicrobial coating composition to a substrate, and allowing the antimicrobial coating composition to dry at ambient conditions.
Patent CA-3170682-A1 (CA)
Inventor: MASSIMINI DANIEL
IPC: A61B18/24
Filed: 2021-03-04
Abstract: A catheter system (100) includes a power source (124), a controller (123), and a light guide (122). The power source (124) generates a plurality of energy pulses (242B, 342B). The controller (123) controls the power source (124) so that the plurality of energy pulses (242B, 342A-B) cooperate to produce a composite energy pulse (348A-B, 448A-C, 548A-F) having a composite pulse shape. The light guide (122) receives the composite energy pulse (348A-B, 448A-C, 548A-F). The light guide (122) emits light energy in a direction away from the light guide (122) to generate a plasma pulse (246A-B, 346A-B) away from the light guide (122). The power source (124) can be a laser and the light guide (122) can be an optical fiber. Each of the energy pulses (242B, 342A-B) has a pulse width, and the energy pulses (242B, 342A-B) are added to one another so that the composite energy pulse (348A-B, 448A-C, 548A-F) has a pulse width that is longer than the pulse width of any one of the energy pulses (242B, 342A-B). At least two of the energy pulses (242B, 342A-B) can have the same wavelength as or a different wavelength from one another.
Patent CA-3174793-A1 (CA)
Inventor: PAULI NATHAN S
Filed: 2022-09-16
Abstract: Cavitation that occurs within a pump (102) of a machine (100), such as truck or other work machine, can potentially damage the pump (102) and/or other components of the machine (100). The machine (100) can have a cavitation monitor (104) configured to detect cavitation and/or cavitation damage associated with the pump (102) based on vibration data (106), speed data (108) associated with mechanical movements of the pump, and operation data (110) associated with the machine (100) overall. If the cavitation monitor (104) detects cavitation and/or cavitation damage, the cavitation monitor (104) can cause corresponding alerts to be displayed to a machine operator or other user.
Patent CA-3175131-A1 (CA)
Inventor: OKUMA CHIHIRO
IPC: C07D403/14
Filed: 2021-03-18
Abstract: One purpose of the present invention is to treat or prevent chronic heart failure. Provided are: a pharmaceutical composition for treating or preventing chronic heart failure, said composition comprising a compound that inhibits SGLT1 or a pharmaceutically acceptable salt thereof; and a treatment or prevention method for chronic heart failure, said method being characterized by comprising administering a compound that inhibits SGLT1 or a pharmaceutically acceptable salt thereof.
Patent CA-3180280-A1 (CA)
Inventor: BAILLIE RHETT A
IPC: C08F4/659
Filed: 2021-05-28
Abstract: Des modes de réalisation de la présente demande concernent des procatalyseurs, et des systèmes de catalyseurs comprenant des procatalyseurs, comprenant un complexe métal-ligand ayant la structure de formule (I) : [Formule I]
Patent CA-3181343-A1 (CA)
Title: An assembly and a system suitable for dispensing a liquid from a compressible bag
Inventor: HESSAM AHMED ABDULLAH
IPC: A61M5/44
Filed: 2021-04-29
Abstract: An assembly and a system suitable for dispensing liquid from a compressible bag, such as for IV treatment of a patient. The assembly includes an apparatus and a flexible mat. The apparatus includes a housing with a dispensing end and an opposite rear end, a floor comprising a flat floor surface, a pair of parallel guiding tracks and a roller arrangement including a roller body. The roller arrangement has a first roller arrangement end and a second roller arrangement end respectively engaged with the respective guiding tracks. The mat has a first mat end, which is mounted to or adapted to be mounted to the roller body and the mat is located at least partly on the flat floor between said guiding tracks.
Patent CA-3183482-A1 (CA)
Title: Antibodies that bind tgf-alpha and epiregulin for use in the treatment of pain
Inventor: CHEDID MARCIO
IPC: C07K16/22
Filed: 2021-06-22
Abstract: The present invention provides for therapeutic use of antibodies that bind human TGF- alpha and human Epiregulin in the treatment of chronic pain, and in particular chronic osteoarthritis pain, chronic diabetic neuropathy pain, or chronic low back pain.
Patent CA-3184746-A1 (CA)
Title: Anti-pd-1 antibodies and fusion proteins
Inventor: LU DAN
IPC: C07K16/28
Filed: 2021-06-23
Abstract: Provided herein are recombinant antibodies, antigen-binding fragments, and fusion proteins thereof useful for binding to and inhibiting programmed death 1 (PD-1), nucleic acid molecules encoding the same and therapeutic compositions thereof, as well as methods of using such antibodies, including the methods for enhancing T cell and NK cell function to increase cell and cytokine mediated immunity and methods of treatment of various immune dysfunction related disorders including cancer and infectious diseases.
Patent CA-3187451-A1 (CA)
Title: Device and method for active noise reduction
Inventor: EWING JAMES C
IPC: G10K11/175
Filed: 2023-01-24
Abstract: The invention provides an active noise reduction system (1) which may be self-contained within a headset (2) of the system (1), wherein circuitry (14) within the system (1) applies an active noise reduction profile (24) to a signal to the speakers in the headset (1), to provide active noise reduction to the user of the headset (2), the system (1) being arranged to both receive power from a power supply external to the system and from a battery (6) of the system and to automatically modify the active noise reduction applied, in dependence on whether or not the system (1) is connected to an external power supply.
Patent CA-3190902-A1 (CA)
Inventor: NEVERMANN JAN
IPC: A01P1/00
Filed: 2021-06-16
Abstract: The present invention relates to a composition containing lemon juice and to the use thereof for cleaning skin and/or hands. The composition comprises 5-30 wt.% lemon juice or lemon juice concentrate, 0.5-10 wt.% phenoxyethanol, 2-60 wt.% anionic surfactant, and the remainder to 100 wt.% being water. The composition is particularly suitable for effectively removing, in a manner that is kind to the skin, dirt containing chlorophyll and/or other plant pigments, plant sap/extracts and/or other plant parts, such as flower and/or plant pollen, and/or phytopathogens, fertiliser residues, herbicides, bactericides, fungicides, virucides and germination inhibiting agents.
Patent CA-3195094-A1 (CA)
Inventor: FORSELL PETER
IPC: A61B90/40
Filed: 2014-01-14
Abstract: A medical device adapted to be position in relation to an incision made in the skin of the patient is provided. The medical device comprises a vacuum sealing device comprising an internal vacuum sealing member adapted to be position inside the body of the patient, for creating a vacuum seal between the medical device and human tissue inside of the skin of the patient. By providing vacuum sealing inside the body of the patient the surface of the skin can be kept unaffected, which means that no hematomas or discoloring of the skin will occur, also the internal vacuum sealing member makes it possible to seal further inside the body of the patient and thereby isolate certain areas in the body of the patient. The vacuum sealing device could for example be adapted to provide sealing against muscle tissue, muscle fascia, fat tissue, the inside of the patient's skin, subcutaneous tissue, the surface of a section made in the body of the patient, a bodily organ, or fibrotic tissue.
Patent CA-3197816-A1 (CA)
Inventor: MATHIESEN VIDAR
IPC: E21B34/08
Filed: 2021-10-25
Abstract: It is provided a fluid flow control device (100) for establishing a controllable fluid communication between an external fluid reservoir and a base pipe (102) constituting part of a production string, as well as a production string and a method using such a fluid flow control device. The fluid flow control device includes a top housing (19) covering the primary flow path inlet (1) of the main housing (8). The fluid flow from the external fluid reservoir flows into top housing in which a fluid flow swirl is induced.
Patent CA-3198928-A1 (CA)
Inventor: GAVATHIOTIS EVRIPIDIS
IPC: A61K31/415
Filed: 2021-09-17
Abstract: A pharmaceutical combination comprising a B-cell lymphoma 2 associated X protein (BAX) activating compound an anti-apoptotic protein inhibiting compound is provided. The disclosure also provides a method of treating cancer in a subject by administering a B-cell lymphoma 2 associated X protein (BAX) activating compound in combination with an anti-apoptotic protein inhibiting compound, such as a BCL-XL, BCL-2, BFL-1. BCL-w, or MCL-1 inhibiting compound.
Patent CA-3199316-A1 (CA)
Title: Acier pour rails et procede de fabrication d'un rail associe
Inventor: CARRASCAL DIEGO
IPC: C22C38/18
Filed: 2020-11-17
Abstract: Acier pour rail comprenant les éléments suivants : 0.25% ? C ? 0.8% ; 1.0% ? Mn ?2.0% ; 1.40% ? Si ? 2% ; 0.01% ? Al ? 1% ; 0.8% ? Cr ? 2% ; 0 ? P ? 0.09% ; 0 ? S ? 0.09% ; 0% ? N ? 0.09% ; 0% ? Ni ? 1% ; 0% ? Mo ? 0.5% ; 0% ? V? 0.2% ; 0% ? Nb ? 0.1% ; 0% ? Ti ? 0.1% ; 0% ? Cu? 0.5% ; 0% ? B ? 0.008% ; 0% ? Sn? 0.1% ; 0% ? Ce ? 0.1% ; 0% ? Mg ? 0.10% ; 0% ? Zr ? 0.10% ; la composition restante étant composée de fer et d'impuretés inévitables provoquées par le traitement, la microstructure dudit acier comprenant, en pourcentage de surface, 2% à 10% de ferrite proeutectoïde, le solde étant constitué de perlite, laquelle présente un espacement interlamellaire de 100nm à 250nm.
Patent CA-3199370-A1 (CA)
Title: Systems and methods for video object segmentation
Inventor: HOMAYOUNFAR NAMDAR
IPC: G01S7/486
Filed: 2021-11-17
Abstract: Systems and methods for generating object segmentations across videos are provided. An example system can enable an annotator to identify objects within a first image frame of a video sequence by clicking anywhere within the object. The system processes the first image frame and a second, subsequent, image frame to assign each pixel of the second image frame to one of the objects identified in the first image frame or the background. The system refines the resulting object masks for the second image frame using a recurrent attention module based on contextual features extracted from the second image frame. The system receives additional user input for the second image frame and uses the input, in combination with the object masks for the second image frame, to determine object masks for a third, subsequent, image frame in the video sequence. The process is repeated for each image in the video sequence.
Patent CA-3199540-A1 (CA)
Title: Container
Inventor: NAKAGAWA HIDEKI
IPC: B05C17/005
Filed: 2021-11-17
Abstract: A container according to the present invention comprises: an inner container provided with a nozzle part that discharges an adhesive filled therein; a cylindrical outer container made of a hard resin, the outer container enclosing the inner container and having an opening formed in an outer circumferential wall; a pressing part made of an elastomer, the pressing part being provided on the outer circumferential wall of the outer container and covering the opening; and a cap covering the nozzle part projected from the outer container and being attachable to and removable from the outer container.
Patent CA-3199605-A1 (CA)
Inventor: BUGDAHN NIKOLAS
IPC: A61K8/49
Filed: 2021-12-09
Abstract: La présente invention concerne le domaine des antioxydants et concerne des compositions cosmétiques ou pharmaceutiques, de préférence dermatologiques, ou un produit d'entretien comprenant ou consistant en une combinaison synergique d'un antioxydant spécifique et d'une quantité efficace de 1,2-heptanediol et/ou de 2,3-heptanediol ou d'un alcanediol spécifique ou d'un mélange d'au moins deux alcanediols spécifiques différents et l'utilisation desdites compositions en tant que produit cosmétique, pour soins personnels, produit pharmaceutique ou d'entretien, en particulier pour piéger des espèces réactives de l'oxygène (ROS), pour inhiber l'expression des métalloprotéinases matricielles et/ou pour inhiber la sécrétion de l'interleukine 8 (IL-8). De plus, la présente invention concerne l'utilisation de 1,2-heptanediol et/ou de 2,3-heptanediol ou d'un alcanediol spécifique ou d'un mélange d'au moins deux alcanediols spécifiques différents pour améliorer l'effet antioxydant d'un antioxydant dans une composition cosmétique ou pharmaceutique, de préférence dermatologique, ou un produit d'entretien, et/ou d'amélioration de l'effet antioxydant d'une composition cosmétique ou pharmaceutique, de préférence dermatologique, lors de l'application.
Patent CA-3200170-A1 (CA)
Inventor: ABD RAHMAN SABRI HARRIS BIN
IPC: G01M99/00
Filed: 2021-11-24
Abstract: Systems and methods for analyzing status of equipment are described. In an embodiment, a method of analyzing equipment, comprises: receiving equipment data comprising indications of measured attribute values of the equipment; looking up an equipment analysis template corresponding to the equipment in a database, the equipment analysis template comprising indications of equipment analysis calculations to be carried out using the measured attribute values of the equipment; analyzing the equipment data according to the equipment template to determine a status of the equipment; and generating an output indication indicating the status of the equipment.
Patent CA-3203124-A1 (CA)
Inventor: BACHALI PRATHYUSHA
IPC: G16H50/30
Filed: 2021-12-28
Abstract: La présente divulgation concerne des systèmes et des procédés de classification par apprentissage automatique de nodules pulmonaires sur la base de données d'expression génique et de données de caractéristiques cliniques. Le procédé peut consister à : a) obtenir un jeu de données contenant des mesures d'expression génique d'un échantillon biologique, provenant d'un patient, d'au moins deux gènes associés à une affection pulmonaire, et des données de caractéristiques cliniques d'une ou de plusieurs caractéristiques cliniques du patient ; b) fournir le jeu de données sous la forme d'une entrée dans un modèle d'apprentissage automatique entraîné pour générer une inférence indiquant si le jeu de données est révélateur d'un nodule pulmonaire malin ou d'un nodule pulmonaire bénin ; c) recevoir, en tant que sortie du modèle d'apprentissage automatique, l'inférence indiquant si le jeu de données est révélateur du nodule pulmonaire malin ou du nodule pulmonaire bénin ; et d) émettre de manière électronique un rapport classifiant le nodule pulmonaire du patient en tant que nodule pulmonaire malin ou nodule pulmonaire bénin.