baber/WOPTO huggingface dataset:
Patent CA-3091905-A1 (CA)
Title: Determining conditions for purification of proteins
Inventor: SHAVER JEREMY MARTIN
IPC: B01D15/16
Filed: 2019-02-21
Abstract: Technologies are described related to determining conditions for the purification of proteins. In some implementations, models can be generated that predict yield and purity for various chromatographic techniques at a number of pH levels and salt concentrations. Training data used to produce the models can be obtained by running chromatography columns using stationary phase materials of different chromatographic techniques at various combinations of pH levels and salt concentrations. In additional implementations, the training data can be obtained by analyzing solutions included in a subset of wells of a multi-well plate, where the subset of wells are associated with particular salt concentrations and pH values for a particular stationary phase material. Further, the models can be used to determine optimized conditions for the purification of various proteins based on maximizing yield and purity, while minimizing cost.
Patent CA-3093179-A1 (CA)
Title: Procede de detection de magea4
Inventor: WILLIAMS AMANDA
IPC: C07K14/47
Filed: 2019-03-07
Abstract: La présente invention concerne un procédé de détection de MAGEA4 dans un échantillon. Le procédé peut comprendre l'ajout d'un anticorps anti-MAGEA4 dans l'échantillon à une concentration comprise dans la plage de 2 à 20 µg/ml, l'incubation de l'anticorps et de l'échantillon et la détection d'un anticorps qui est lié à l'échantillon. Les procédés de l'invention peuvent être utilisés pour diagnostiquer si un sujet présente un cancer et si le sujet est éligible pour Un traitement avec une thérapie anticancéreuse ciblée MAGEA4.
Patent CA-3093536-A1 (CA)
Inventor: SEILER ANDREAS
IPC: B01F29/83
Filed: 2019-03-14
Abstract: The invention relates to a mixing device comprising a mixing container (1) for receiving material to be mixed and a mixer cover (12), wherein a first seal (5) is provided between the mixing container (1) and mixer cover (12). In order to provide a mixing device which at least reduces the described disadvantages, according to the invention, a second seal (6) is provided and the first and the second seal (5, 6) are arranged in such a way that a first air space (11) is formed between the first and the second seal (5, 6).
Patent CA-3094087-A1 (CA)
Inventor: LAGOW ROBERT
IPC: A61M39/22
Filed: 2019-03-19
Abstract: A disposable valve assembly configured for use with an endoscope is disclosed. The disposable valve assembly may include a stem comprised of thermoplastic material, a spring stanchion configured to receive the stem and allow movement of the stem in an upward and downward position relative to the spring stanchion, a spring configured to contact that spring stanchion and the stem. In some embodiments, a lubricant is disposed on the stem, the spring stanchion and/or the spring. The disposable valve assembly may also include an antimicrobial agent disposed in the lubricant, or in the thermoplastic material and/or can be coated thereon. A method for manufacturing the disposable valve assemblies for use with an endoscope may include several steps.
Patent CA-3095619-A1 (CA)
Title: Brake assembly for a tracked vehicle
Inventor: VAN MILL MICHAEL D
IPC: B62D55/08
Filed: 2020-10-06
Abstract: A farm implement is provided having a frame and first and second track assemblies for assisting in moving the farm implement along a ground surface in a line of travel. The first track assembly and the second track assembly are positioned on opposite lateral sides of the frame.  The first track assembly has a first track frame, a first idler wheel, and a first brake assembly.  The first idler wheel has an inboard side facing toward a center of the first track frame and an outboard side facing away from the center the first track frame. The first brake assembly has a first disc coupled to the first idler wheel on the outboard side of the first idler wheel, a first caliper couplable to first and second sides of the first disc, and a first torque arm coupled to the first track frame and a spindle of the first idler wheel. The first caliper is mounted on the first torque arm, and the first caliper is configured to clamp down on the first and second sides of the first disc in order to slow and/or stop rotation of the first idler wheel.
Patent CA-3096794-A1 (CA)
Title: Casing angle adjustment mechanism and electronic device
Inventor: KOBAYASHI MASAKI
IPC: H04M1/22
Filed: 2020-06-23
Abstract: A casing angle adjustment mechanism capable of adjusting the angle of a casing with respect to a mounting surface by a simple operation of a leg unit is provided. When an angle adjustment mechanism (3) of a casing (2) rotates a leg unit (5) in one direction, moves a part of a stopper (6) along a connection hole (5d) of the leg unit (5), and slides a slide plate (4) through a first protrusion (4b), a side wall of the slide plate (4) blocks openings of engagement holes (5c) of the leg unit (5), and a side wall of the leg unit (5) blocks openings of engagement grooves (4a) of the slide plate (4), and when it rotates the leg unit (5) in another direction, moves the part of the stopper (6) along the connection hole (5d) of the leg unit (5), and slides the slide plate (4) through the second protrusion (4c), a plurality of engagement grooves (4a) of the slide plate (4) and a plurality of engagement holes (5c) of the leg unit (5) are placed to overlap.
Patent CA-3097078-A1 (CA)
Title: Method for producing a metal bladed element for a turbomachine of an aircraft
Inventor: SOISSON MARC
IPC: B23P15/02
Filed: 2019-04-19
Abstract: The invention relates to a method for producing a metal bladed element for a turbomachine of an aircraft, said bladed element comprising at least one blade having a lower surface and an upper surface extending between a leading edge and a trailing edge of the blade, the trailing edge having to have a thickness X1, said method comprising the steps of: a) producing the bladed element by lost-wax casting, and b) finishing the bladed element, characterised in that step b) comprises the chemical milling at least of the trailing edge of the or each blade so as to obtain said thickness X1 which cannot be directly obtained by step a).
Patent CA-3099333-A1 (CA)
Title: Panel with stone veneer
Inventor: DOHRING DIETER
IPC: B44C5/04
Filed: 2018-06-08
Abstract: The present invention relates to a panel (20) and a method for manufacturing such a panel, in particular awall, ceiling or flooring panel, comprising a carrier board (10) with a front surface and a rear surface. The carrier board (10) is a mineral wool board or a fiber cement board with a thickness of 3 to 30 mm and comprises on its front surface a layer (26) made of a stone veneer.
Patent CA-3101608-A1 (CA)
Inventor: LAYMAN JOHN MONCRIEF
IPC: C08L23/06
Filed: 2019-06-18
Abstract: L'invention concerne un procédé de purification d'un polyéthylène recyclé. Selon un mode de réalisation, le procédé consiste à obtenir du polyéthylène recyclé, à mettre en contact le polyéthylène recyclé avec un premier solvant liquide pour produire un polyéthylène recyclé extrait ; puis à dissoudre le polyéthylène recyclé extrait dans un solvant pour produire une première solution comprenant du polyéthylène. La première solution est décantée puis filtrée. Un polyéthylène plus pur est ensuite séparé de la solution résultante.
Patent CA-3101922-A1 (CA)
Title: Composite transport container for beverages
Inventor: PEIRSMAN DANIEL
IPC: B65D81/02
Filed: 2019-06-05
Abstract: A container for transporting beverage said container comprising at least one part made of a sandwich structural laminate comprising a PU and/or PET foam core, a resin outer skin and a resin inner skin.
Patent CA-3103715-A1 (CA)
Inventor: DRNEVICH RAYMOND F
IPC: C01B3/56
Filed: 2019-06-27
Abstract: A method for operating a hydrogen generation system comprising: producing a synthesis gas stream in a steam reformer which has a combustion zone; introducing at least a portion of the synthesis gas stream to a water gas shift reactor; cooling the shifted synthesis gas stream to produce a cooled shifted synthesis gas stream; introducing the cooled shifted synthesis gas stream into a pressure swing adsorption unit, thereby producing a stream of predominantly hydrogen and a tail gas comprising predominantly byproducts; routing said tail gas to one or more surge tank(s) having a heat exchange device disposed therein and indirectly heating said tail gas by passing it over a surface of said heat exchange device inside which a hot fluid is cooled, thereby obtaining a heated tail gas; and routing said heated tail gas to the combustion zone of the reformer.
Patent CA-3105197-A1 (CA)
Inventor: MEDVEDEV ANATOLY VLADIMIROVICH
IPC: E21B33/138
Filed: 2019-06-28
Abstract: L'invention concerne la préparation de coulis de ciment qui comprennent de l'eau, un ciment hydraulique et des particules d'un matériau absorbant l'huile. Les particules sont présentes en une quantité suffisante pour modifier une propriété d'un fluide de forage non aqueux. Le coulis de ciment est placé dans un puits souterrain, après quoi le coulis entre en contact avec le fluide de forage résiduel sur les surfaces de l'enveloppe et de la formation. Le matériau absorbant l'huile dans le coulis de ciment peut réduire la mobilité du fluide de forage, ce qui permet d'améliorer l'isolation zonale.
Patent CA-3105965-A1 (CA)
Title: Charbon actif modifie et ses procedes d'utilisation
Inventor: REDDING ADAM M
IPC: C02F1/28
Filed: 2019-08-14
Abstract: L'invention concerne du charbon actif modifié destiné à être utilisé dans le traitement de l'eau. Dans au moins certains modes de réalisation, le charbon actif peut être traité avec un tensioactif chargé positivement, c'est-à-dire un tensioactif à base d'ammonium quaternaire, pour favoriser l'élimination de substances poly- et perfluorolkyle à partir de l'eau.
Patent CA-3106108-A1 (CA)
Inventor: RUTITZKY LAURA
IPC: C07K16/12
Filed: 2019-07-11
Abstract: Fc-antigen binding constructs having a PD-L1 binding domain and two or more Fc domains are described as are methods for using such constructs. Also described are polypeptides making up such constructs. Fc domain monomers that are included in the constructs can include amino acid substitutions that promote homodimerization or heterodimerization.
Patent CA-3109921-A1 (CA)
Inventor: JACKSON DAN
IPC: G06N3/02
Filed: 2021-02-24
Abstract: A vehicle recommender system includes a storage system storing a trained neural network trained to generate a vehicle recommendation, a vehicle database comprising vehicle attribute data, and a driver database comprising driver profile data. A  processing system communicates with the storage system and is configured to generate enriched driver profile data by comparing user-generated driver profile data to the location characteristic data and social characteristic data. The processing system calculates a driver attribute target value for each vehicle attribute category in a list of vehicle attribute categories based on the driver profile data, and then generates, using the trained neural network, at least one vehicle recommendation based on at least the vehicle attribute data and the driver attribute target values.
Patent CA-3112211-A1 (CA)
Title: Compositions and methods for multiplexed quantitative analysis of cell lineages
Inventor: WINSLOW MONTE M
IPC: C12Q1/6823
Filed: 2019-10-01
Abstract: Compositions and methods are provided for measuring population size for a plurality of clonal cell populations in the same individual, e.g., for measuring tumor size for a plurality of clonally independent tumors within the same individual. A subject method can include: (a) contacting an individual with a plurality of cell markers that are heritable and distinguishable from one another, to generate a plurality of distinguishable lineages of heritably marked cells; (b) after sufficient time has passed for the heritably marked cells to undergo at least one round of division, detecting and measuring quantities of at least two of the plurality of cell markers present in the contacted tissue, thereby generating a set of measured values; and (c) using the set of measured values to calculate the number of heritably marked cells that are present (e.g., for at least two of the distinguishable lineages of heritably marked cells).
Patent CA-3114123-A1 (CA)
Title: Composition destinee a etre utilisee en tant que stabilisateur de peroxyde
Inventor: LI ZHIJIAO
IPC: D21C9/16
Filed: 2018-11-07
Abstract: L'invention concerne une composition destinée à être utilisée en tant que stabilisateur de peroxyde dans le blanchiment de pâte, qui comprend un acide iminodisuccinique (IDS) ou ses sel(s), et un sel de sodium d'un acide polyaspartique (PASP).
Patent CA-3115025-A1 (CA)
Inventor: PELLEGRINI PABLO
IPC: A61Q19/08
Filed: 2019-10-10
Abstract: La présente invention concerne l'utilisation d'un peptide comprenant la séquence d'ID No. 1 et une composition cosmétique associée dans le traitement et la prévention du vieillissement et du photovieillissement de la peau.
Patent CA-3115384-A1 (CA)
Title: Polymer dispersion by controlled radical polymerization
Inventor: CHENG ZHENXING
IPC: C09K23/52
Filed: 2018-10-11
Abstract: Disclosed is a polymer dispersion prepared by controlled radical polymerization and a use of the polymer dispersion as a friction reducer in oil field processes.
Patent CA-3119792-A1 (CA)
Title: Composes, compositions et methodes pour traiter la septicemie
Inventor: KJOLBYE ANNE LOUISE SOBERG
IPC: A61P9/04
Filed: 2019-11-14
Abstract: L'invention concerne des compositions comprenant de la sélépressine à utiliser dans le traitement de la septicémie chez un patient. La composition comprenant de la sélépressine peut être administrée dans les six heures à partir du moment où le patient nécessite une thérapie par vasopresseur. Les patients peuvent avoir une concentration de lactate sérique inférieure à environ 2 mmol/L avant le traitement et/ou un rapport entre l'oxygène artériel sous pression partielle et une fraction d'oxygène inspiré (PaO2/FiO2) supérieur à environ 200 avant le traitement. L'invention concerne également des méthodes associées.
Patent CA-3120044-A1 (CA)
Inventor: PETERS CHRISTOPHER
IPC: G01B11/14
Filed: 2019-11-08
Abstract: The position detector (1) of an object comprises a body (2) defining an input (3) receiving an optical fibre (4) delivering a light signal, and an output delivering a signal representative of the position of the object. A mirror (5) is mounted to move between first and second positions in the body (2) with respect to the input. The first position or the second position ensures transmission of the light signal from the input (3) to the output. The other of the first position and the second position prevents transmission of the light signal to the output. A spring (6) is mounted in the body (2) in order to place the mirror (5) in the first position. A tip (7) is movable relative to the body (2) between a first position and a second position along a direction of movement and is intended to cooperate with the object to be monitored.
Patent CA-3125035-A1 (CA)
Inventor: DEVI RAVINDRA
IPC: F01D25/00
Filed: 2019-12-26
Abstract: L'invention concerne un composant aérodynamique de stator (130, 250) qui est destiné à être placé à l'intérieur d'un trajet d'écoulement (500) d'un fluide de travail d'une turbomachine (1000) ; le composant (130, 250) a une ou plusieurs buses (135, 255) servant à éjecter un liquide dans le trajet d'écoulement (500) ; le liquide destiné à être éjecté provient d'un conduit (134, 254) interne au composant (130, 250) et en communication fluidique avec un tuyau (120, 220) qui est externe au composant (130, 250). L'invention concerne également un procédé de nettoyage d'une turbomachine par éjection d'un liquide de lavage en provenance d'un ou de plusieurs composants aérodynamiques de stator.
Patent CA-3126162-A1 (CA)
Inventor: XIANG JIA-NING
IPC: C07D221/00
Filed: 2019-07-08
Abstract: Ketamine derivatives and pharmaceutical compositons thereof are disclosed. When administered orally the ketamine derivatives provide increased bioavailability of ketamine in the systemic circulation. The ketamine derivatives can be used to treat neurological diseases, psychological diseases and pain.
Patent CA-3126839-A1 (CA)
Inventor: JUNGLES STEVEN
IPC: A01K67/02
Filed: 2020-01-20
Abstract: La présente invention concerne, entre autres, des vecteurs pour l'expression d'ENPP1 ou ENPP3 in vivo et des méthodes de traitement de maladies de calcification et d'ossification chez un sujet.
Patent CA-3129459-A1 (CA)
Title: Assemblies for alignment and levelling of an electrolytic tank upon expansion or retraction thereof
Inventor: DUFRESNE ROBERT
IPC: C25C1/00
Filed: 2020-02-11
Abstract: There is provided an electrolytic tank assembly facilitating alignment and levelling of an electrolytic tank with respect to adjacent electrolytic tank. A levelling assembly can include a plurality of adjustable levelling mechanisms being independently actuable to cause upward or downward movement of the electrolytic tank. A sole assembly can include friction and sliding soles for controlling transversal movement of an electrolytic tank with respect to support beams onto which the tank is supported. A strap assembly comprising a vertically extending strap and a connector provided at an end of the vertically extending strap can be connected to each adjustable levelling mechanism of the levelling assembly. Various type of connectors can be provided at the other end of the strap to provide anchorage to accessory for operation, lifting, maintenance, etc.
Patent CA-3129634-A1 (CA)
Inventor: GASPAR NUNO MIGUEL PIRES
IPC: G06F16/2455
Filed: 2020-02-13
Abstract: De multiples requêtes de base de données formant une requête de base de données complexe sont traitées. Une première requête et une deuxième requête sont soumises à une réponse par une première réponse et une seconde réponse d'après une mémoire cache stockant des données mises en mémoire cache. Une troisième requête qui est associée à la deuxième requête reçoit une réponse d'après une base de données stockant des données actuelles correspondant aux données mises en mémoire cache. Un sous-ensemble sélectionné des données mises en mémoire cache renvoyées avec la seconde réponse est validé par les données actuelles correspondantes stockées dans la base de données.
Patent CA-3129742-A1 (CA)
Title: Systems and methods for managing, validating, and transmitting health data across geographic regions
Inventor: YOUSFI RAZIK
IPC: G06Q50/00
Filed: 2020-02-21
Abstract: Systems and methods are disclosed for preserving patient privacy while allowing health data to be analyzed, managed, and stored in different geographical areas. One method for managing cross-border health data while preserving patient privacy includes: receiving a DICOM object from a hospital computing device for analysis; generating a unique case identifier for the DICOM object; validating the received DICOM object; if, based on the validation, the received DICOM object is valid, anonymizing the received DICOM object; updating the anonymous DICOM object to include the unique case identifier; compressing the updated DICOM object; and sending the compressed DICOM object to at least one data analysis web service(s).
Patent CA-3131431-A1 (CA)
Title: Solid forms of a toll-like receptor modulator
Inventor: ASSELIN SYLVIE M
IPC: C07D471/04
Filed: 2020-04-15
Abstract: The present disclosure provides crystalline forms, solvates and hydrates of (R)- 2- ((2-amino-7-fluoropyrido[3,2-d]pyrimidin-4-yl)amino)-2-methylhexan-l-ol, and methods of making.
Patent CA-3133545-A1 (CA)
Inventor: GALETTO ROMAN
IPC: A61K35/17
Filed: 2013-05-13
Abstract: A method of expanding TCRalpha deficient T-cells by expressing pTalpha or functional variants thereof into said cells, thereby restoring a functional CD3 complex. This method is particularly useful to enhance the efficiency of immunotherapy using primary T-cells from donors. This method involves the use of pTalpha or functional variants thereof and polynucleotides encoding such polypeptides to expand TCRalpha deficient T- cells. Such engineered cells can be obtained by using specific rare-cutting endonuclease, preferably TALE-nucleases. The use of Chimeric Antigen Receptor (CAR), especially multi- chain CAR, in such engineered cells to target malignant or infected cells. The invention opens the way to standard and affordable adoptive immunotherapy strategies for treating cancer and viral infections.
Patent CA-3136200-A1 (CA)
Inventor: PAK JANICE
IPC: A61M39/28
Filed: 2020-04-07
Abstract: Roller clamps are described herein. A roller clamp includes a housing, a roller wheel, and a locking device. The housing includes a first wall and a second wall, wherein the first wall and the second wall are spaced apart to define a longitudinal channel therebetween, the housing including an upper opening and a lower opening configured to allow a tubing to pass through the longitudinal channel. The roller wheel is disposed at least partially within the longitudinal channel and configured to engage the tubing, the roller wheel including a plurality of teeth extending from an outer surface of the roller wheel, wherein a longitudinal position of the roller wheel relative to the channel adjusts a flow rate through the tubing. The locking device is releasably engaged to the housing and the roller wheel, wherein the locking device prevents movement of the roller wheel from the longitudinal position.
Patent CA-3137586-A1 (CA)
Title: Preconnected analyte sensors
Inventor: BARRY JOHN CHARLES
IPC: A61B5/05
Filed: 2020-04-21
Abstract: Various analyte sensing apparatuses and associated housings are provided. Some apparatuses comprise one or more caps. Some apparatuses comprise a two-part adhesive patch. Some apparatuses comprise one or more sensor bends configured to locate and/or hold a sensor in place during mounting. Some apparatuses utilize one or more dams and/or wells to retain epoxy for securing a sensor. Some apparatuses utilize a pocket and one or more adjacent areas and various transitions for preventing epoxy from wicking to undesired areas of the apparatus. Some apparatuses include heat-sealable thermoplastic elastomers for welding a cap to the apparatus. Related methods of fabricating such apparatuses and/or housings are also provided.
Patent CA-3142010-A1 (CA)
Inventor: NEVES LEANDRO GOMIDE
IPC: E04C2/24
Filed: 2020-05-29
Abstract: L'invention concerne des matériaux et des procédés de capture d'une région génomique cible, consistant à hybrider une sonde d'extension et une sonde de ligature en vue de cibler des séquences qui encadrent la région génomique cible; à allonger l'extrémité 3' de la sonde d'extension jusqu'à ce que l'extrémité 3'de la sonde d'extension allongée soit adjacente à l'extrémité 5' de la sonde de ligature; et à ligaturer l'extrémité 3' de la sonde d'extension allongée avec l'extrémité 5' de la sonde de ligature pour produire une sonde ligaturée. La sonde ligaturée peut être amplifiée par PCR pour produire des copies de la région génomique cible qui peuvent être détectées ou séquencées. Certains modes de réalisation de l'invention concernent également des procédés de production de sondes à double brin appropriées pour capturer et analyser les deux brins d'une région génomique cible dans un ADN génomique à double brin. L'invention concerne également des kits permettant de mettre en uvre les procédés de l'invention.
Patent CA-3150413-A1 (CA)
Inventor: FURLING DENIS
IPC: C12N15/63
Filed: 2020-09-11
Abstract: La présente invention concerne le domaine de la thérapie génique. En particulier, l'invention concerne une molécule d'acide nucléique comprenant une séquence d'acide nucléique pouvant réguler l'expression d'un transgène d'intérêt, un vecteur ou une cellule comprenant ladite molécule d'acide nucléique, et ses utilisations.