baber/WOPTO huggingface dataset:
Patent CO-5560589-A2 (CO)
Title: 6,7-dihidro-5h-pirazol[1,2-a]pirazol-1-onas que controlan citosinas inflamatorias
Inventor: LAUFERSWEILE MATTHEW JOHN
IPC: A61K31/5377
Filed: 2004-03-09
Abstract: 1.- Un compuesto que incluye todas las formas enantioméricas y diasterioméricas y las sales farmacéuticamente aceptables de las mismas, el compuesto corresponde a la fórmula: caracterizada además porque R es: a) -O[CH2]kR3; o b) -NR4aR4b;R3 es alquilo C1-C4 sustituido o no sustituido, hidrocarbilo sustituido o no sustituido, heterociclilo sustituido o no sustituido, arilo o alquilenarilo sustituido o no sustituido, heteroarilo o alquilenheteroarilo sustituido o no sustituido; el subíndice k es de 0 a 5;R4a y R4b son independientemente: a) hidrógeno; o b) -[C(R5aR5b)]mR6;cada R5a y R5b son independientemente hidrógeno, -OR7, -N(R7)2, -CO2R7, -CON(R7)2; alquilo C1-C4 lineal, ramificado o cíclico, y mezclas de los mismos; R6 es hidrógeno, -OR7, -N(R7)2, -CO2R7, -CON(R7)2; alquilo C1-C4 sustituido o no substituido, aril heterociclo sustituido o no sustituido, arilo sustituido o no sustituido o heteroarilo sustituido o no sustituido; R7 es hidrógeno, un catión hidrosoluble, alquilo C1-C4 arilo sustituido o no sustituido; el subíndice m es de 0 a 5;R1 es: a) arilo sustituido o no sustituido; o b) heteroarilo sustituido o no sustituido;cada unidad R2 de manera independiente se selecciona del grupo que consiste de: a) hidrógeno, b) -(CH2)jO(CH2)nR8; c) -(CH2)jNR9aR9b; d) -(CH2)jCO2R10; e) -(CH2)jOCO2R10 f) -(CH2)jCON(R10)2; g) -(CH2)jOCON(R10)2; h) dos unidades R2 se pueden unir entre sí para formar una unidad carbonilo; i) y mezclas de los mismos;R8, R9a, R9b y R10 son independientemente hidrógeno, alquilo C1-C4 y mezclas de los mismos; R9a y R9b se pueden unir entre sí y formar un anillo carbocíclico o heterocíclico que tiene de 3 a 7 átomos; dos unidades R10 se pueden unir entre sí y formar a anillo carbocíclico o heterocíclico que tiene de 3 a 7 átomos; el subíndice j tiene un valor de 0 a 5, el subíndice n tiene un valor de 0 a 5;Z es O, S, NR11 o NOR11; R11 es hidrógeno o alquilo C1-C4.
Patent CO-6180436-A2 (CO)
Title: Compuesto agonista y antagonistas del receptor esfingosina- 1- fosfato
Inventor: WALLACE GRIER
IPC: A01N43/50
Filed: 2009-06-02
Abstract: 1.- Un compuesto de la Fórmula Ien donde D es H, N(R5)2 u OR6;X es CH, C(CH3) o N; Y es CH2, O, S o NR3; en donde R3 es hidrógeno, o alquil (C1-C10) recto o ramificado; A es H, hidroxi, -CH2OH, -CH(OH)CH3, -C(O)-OCH3, -C(OH)(CH3)2, -O(CH2)t-COOH, -C(O)-NR6, -(CH2)-P(=O)(OR7)(OR7) opcionalmente substituido, -(CH2)n-O-P(=O)(OR7)(OR7) opcionalmente substituido, -(CH2)n- P(=O)(OR7)(R7) opcionalmente substituido, -CH=CH-P(=O)(OR7)(OR7), C(O)-NHCH3, CN, COOR6 o -R4-COOH, en donde R4 es alquileno (C1-C20) recto o ramificado, alquenileno (C1-C20) recto o ramificado, alquinileno (C1- C20) recto o ramificado, cicloalquil (C3-C20), o azetidinil opcionalmente substituido;R1 y R2 son seleccionados, de forma independiente, a partir del grupo que consiste de hidrógeno, CF3, halógeno, alquil (C1-C20), alcoxi (C1-C20), alquil substituido con cicloalquil (C3-C20), alcoxi substituido con cicloalquil (C3-C20), alquenil (C2-C20), alquenil (C2-C20) substituido con aril, alquinil (C2- C20), alquinil (C2-C20) substituido con aril, aril, alquil (C1-C20) substituido con aril, alquil (C2-C20) substituido con heteroanil, alcoxi substituido con aril, alcoxi substituido con heteroaril, aril substituido con alquil, arilalquil, arilalquil substituido con aril, arilalquil substituido con arilalquil, CN y -O-indolizinil; en donde tales grupos R1 y R2 pueden ser opcionalmente substituidos con uno o más substituyentes seleccionados, de forma independiente, a partir de alquil (C1-C20), CF3, halógeno, hidroxi, alcoxi (C1-C20), OCF3, y CN; en donde uno o más de los átomos de carbono en los grupos R1 o R2 pueden ser independientemente reemplazados con oxígeno que no es de peróxido, azufre o NR8;en donde R8 es hidrógeno o el grupo alquil (C1-C20); en donde uno de R1 y R2 es diferente de hidrógeno; y en donde los grupos alquil, alquenil, y alquinil en R1 y R2 son opcionalmente substituidos con oxo o halógeno; cada R5 es independientemente H, alquil (C1-C3) opcionalmente substituido, o fenil opcionalmente substituido con -C(O)-O-alquil(C1-C3); cada R6 es independientemente H o alquil (C1-C2) opcionalmente substituido; ...
Patent CO-6280590-A2 (CO)
Title: Procedimiento de cierre del extremo de envolturas tubulares plisadas para el embutido de productos carnicos
Inventor: OLLETA REMON AGUSTIN
IPC: A22C13/00
Filed: 2010-09-08
Abstract: 1.- Un dispositivo para luchar contra insectos que consiste de una estructura interna hecha de material biodegradable basado en celulosa, impregnado con una sustancia volátil o una mezcla de sustancias volátiles, y un recubrimiento exterior hecho de un material biodegradable basado en almidones y polímeros termoplásticos, dicho dispositivo siendo extruido en la forma de un hilo continuo.2.- El dispositivo de acuerdo con la reivindicación 1, en donde dicha sustancia volátil es una feromona o una mezcla de feromonas.3.- El dispositivo de acuerdo con la reivindicación 2, en donde dicha feromona o una mezcla de feromonas es específica para cada uno de los siguientes insectos: Cydia molesta, Anarsia lineatella, Cydia funebrana, Cydia pomonella, Heliothis armigera, Lobesia botrana, Mamestra brassicae, Spodoptera exigua, Spodoptera littoralis, Spodoptera frugiperda, Heliothis armigera. 4.- El dispositivo de acuerdo con la reivindicación 1, en donde dicha sustancia volátil es tert-butilo (±) -4 (o 5) - cloro-2-metilo ciclohexano carboxilato específico para Ceratitis_capitata.
Patent CO-6321224-A2 (CO)
Title: Preparacion solida de desintegracion oral que contiene granulos finos que muestran una liberacion controlada de un principio activo para uso farmaceutico
Inventor: KURASAWA TAKASHI
IPC: A61K9/20
Filed: 2010-10-11
Abstract: La presente invención provee una preparación sólida de desintegración oral tales como un comprimido producido formando comprimidos de gránulos finos que muestran una liberación controlada de un principio activo para uso farmacéutico y un aditivo, y similares, y la preparación sólida de desintegración oral que contiene gránulos finos recubiertos con una capa de recubrimiento que contiene un polímero que produce una película de recubrimiento que tiene una elongación en la ruptura de alrededor de 100 - alrededor de 700%. Con la preparación, la ruptura de los gránulos finos durante la formación del comprimido puede suprimirse en la producción de una preparación sólida de desintegración oral que contiene los gránulos finos que muestran una liberación controlada de un principio activo para uso farmacéutico.
Patent CO-6341628-A2 (CO)
Title: \\\\\\\"nuevos compuestos adecuados como precursores de compuestos que son utiles para obtener imegenes de depositos amiloides\\\\\\\"
Inventor: BJORK SETH
IPC: C07D405/04
Filed: 2011-02-21
Abstract: La presente invención se refiere a nuevos derivados que son adecuados corno precursores de compuestos útiles para obtener imágenes de depósitos amiloides en pacientes vivos, a sus composiciones, a métodos de uso y a procesos para preparar dichos compuestos. Los compuestos que derivan de estos precursores son útiles en métodos de imaginología in vivo de depósitos amiloides en el cerebro para permitir el diagnóstico ante mortem de la enfermedad de Alzheimer mediante tomografía por emisión de positrones (PET) así como la medición de la eficacia clínica de agentes terapéuticos para la enfermedad de Alzheimer. Además, la presente invención también divulga los compuestos precursores en forma cristalina.Sector: Productos farmacéuticos para el diagnostico y tratamiento de enfermedades del sistema nervioso, en particular compuestos heterocíclicos de dos anillos fusionados que contienen oxígeno, los cuates pueden emplearse corno precursores de compuestos que permiten obtener imágenes de depósitos amiloides, por ejemplo para el diagnostico de enfermedades corno el Alzheimer.
Patent CO-6400208-A2 (CO)
Title: Producto fibroso con un releieve entramado y método para producir el mismo
Inventor: SAUTER JURGEN
IPC: B31F1/07
Filed: 2011-07-06
Abstract: Un producto fibroso (10, 20, 20b, 30), especialmente el producto de papel tisú, producto no tejido o un híbrido de los mismos, y preferiblemente producto de higiene y limpieza, con por lo menos una primera capa (42; 62; 84; 104) con por lo menos un patrón de estampado en relieve que comprende depresiones en relieve iniciado desde un plano de base de la capa; el patrón de estampado en relieve siendo caracterizado por los siguientes aspectos: el patrón de estampado en relieve tiene un área superficial de motivo mínima de por lo menos 3 cm x 3 cm; el patrón de estampado en relieve comprende un alto número de depresiones en relieve que se dimensionan y/o posicionan de manera que forman un elemento de motivo que cubre el área superficial de motivo; en donde por lo menos algunas de las depresiones en relieve se dimensionan y/o colocan de manera que varían las distancias mínimas entre los pares de la depresión en relieve dispuesta consecutivamente. La invención también se refiere a un método para producir dicho producto fibroso.
Patent CO-6470820-A2 (CO)
Title: Espiro-epóxidos como productos intermedios
Inventor: SCUTT JAMES NICHOLAS
IPC: C07D309/32
Filed: 2011-11-24
Abstract: La presente invención proporciona compuestos de fórmula Ien donde los sustituyentes son como se definen en la reivindicación 1. Los compuestos son productos intermedios apropiados para la preparación de 4-fenil-35-pirandiones, 4-fenil-3,5- tiopirandiones y 6-fenilciclohexano-1, 3, 5-triones activos como herbicidas.
Patent CO-6541574-A2 (CO)
Title: Método para agrietar hidráulicamente una formación
Inventor: MACK LANCE WILLIAM
IPC: E21B43/26
Filed: 2012-05-14
Abstract: Un método para agrietar hidráulicamente una formación que comprende controlar un caudal de bombeo durante el agrietamiento hidráulico de la primera sección del agujero de pozo horizontal durante un primer periodo para romper la formación mientras se reduce la recolección de arena posicionada en el agujero del pozo; durante un segundo periodo posterior a la recolección de la arena posicionada en el agujero de pozo generalmente a un caudal en la que la formación aceptará la arena; y, durante un tercer periodo posterior para agrietar la formación.
Patent CO-6602133-A2 (CO)
Title: Derivados de i,idazo(1,2-a)pirazina y su uso para la prevencion o tratamiento de trastornos y enfermedades neurologicas, siquiatricas y metabolicas
Inventor: BARTOLOME NEBREDA JOSE MANUEL
IPC: C07D487/04
Filed: 2012-08-31
Abstract: La presente invención se refiere a nuevos derivados de imidazo[1,2-a]pirazina que son inhibidores de la enzima fosfodiesterasa 10 (PDE1O) y que resultan útiles para el tratamiento o la prevención de trastornos neurológicos, psiquiátricos y metabólicos en los cuales participa la enzima PDE1O. La invención también se dirige a composiciones farmacéuticas que comprenden dichos compuestos, a procesos para preparar dichos compuestos y composiciones, y al uso de dichos compuestos o composiciones farmacéuticas para la prevención o el tratamiento de trastornos y enfermedades neurológicas, psiquiátricas y metabólicas.
Patent EP-1063083-A2 (EP)
Inventor: GRAAE NIELS
IPC: B32B11/10
Filed: 2000-05-18
Abstract: The underside (1) is a thermoplastic fleece, the next layer is bitumen (2), especially elastomeric bitumen. The supporting inlay (3) is a tensile layer of fleece or fabric. A further layer of elastomeric bitumen (4) is covered by an upper separation layer (5) with an edge strip, allowing welding with the underside of the overlapping edge strip of a similar sealing band. At the edge, a bitumen strip (6) on the upper or lower layer (1 or 5) is self-adhesive in the cold state, and is covered by a backing strip (6a, 7a).
Patent EP-1103728-A2 (EP)
Inventor: BUETER JOSEF
IPC: F15B15/26
Filed: 2000-06-02
Abstract: Fitted in a motion locking part (4) and/or a bottom locking part, an electrically insulated contact pin (17) opposite to a working cylinder is designed as a closer in contact with a locking piston (7) in a modular unit (6) for locking end of travel.
Patent EP-1069283-A2 (EP)
Inventor: IIDA TATSUO
IPC: F01L9/20
Filed: 2000-07-11
Abstract: In an internal combustion engine having a plurality of
electromagnetically driven valves (16a, 16b) for each
cylinder, when a required EGR amount Er is relatively
small during an exhaust gas recirculation performed
independently of the exhaust stroke, a first exhaust gas
recirculation mode (S310 to S350) is entered by driving
only a first exhaust valve of each cylinder. An open valve
duration Td1 for achieving the required EGR amount Er in a
one-valve drive manner is longer than a corresponding open
valve duration in a two-valve drive manner. Therefore,
even if the required EGR amount Er is small, a "one-valve
drive in pattern 1" mode can be achieved provided that Td1
> a. That is, the incidence of performing the control in
pattern 2, which allows only a narrow range of control, can
be reduced. Hence, degradation of controllability can be
prevented even if the required EGR amount Er is small.
Patent EP-1076299-A2 (EP)
Inventor: FLAKE GARY WILLIAM
IPC: G06F17/30
Filed: 2000-08-11
Abstract: A method for partitioning a database containing
a plurality of documents into desired and undesired type
documents is provided. The plurality of documents contain
text and/or links to and from other documents in the
database. The method includes the steps of: providing a
source document of the desired type; providing a sink
document for providing access to the database;
identifying a cut-set of links which is the smallest set
of links such that removing them from the database
completely disconnects the source document and its linked
documents from the sink document and its linked documents
into first and second subsets of documents, respectively;
and defining the first subset of documents as desired
type documents and the remaining documents as undesired
type documents. Preferably, the database is the World
Wide Web, the documents are web pages, and the links are
hyperlinks between web pages. The identifying step
preferably comprises: mapping at least a portion of the
database into a graph structure; and
applying a maximum flow algorithm to the graph structure,
the subset of the graph structure which remains after
application of the maximum flow algorithm being the first
subset of documents. Also provided are a computer
program product and program storage device for carrying
out the method of the present invention and for storing a
set of instructions to carry out the method of the
present invention, respectively.
Patent EP-1104712-A2 (EP)
Inventor: BURROWS ANDREW JULIAN
IPC: B60K6/48
Filed: 2000-11-04
Abstract: A gear selection arrangement in which in a hybrid vehicle with an electric
motor that motor is used as an independent drive means in order to provide a
balancing torque upon an input shaft to a speed change transmission 13 in order to
compensate for gearbox torque loss as a result of friction and lubrication etc. By
such means, when the transmission 13 is in a neutral state the electric motor 1
can ensure that the input shaft 6 to the transmission 13 is always at a rotational
speed below that of the main shaft from the transmission 13 such that irrespective
of the actual gear ratio change effected by the transmission 13 the synchronisation
process is that substantially of a downshift gear ratio. In such circumstances, the
input shaft 6 must always accelerate to the main shaft desired rotational speed
rather than vice versa.
Patent EP-1100060-A2 (EP)
Inventor: JUNG CHAE-SUNG
IPC: G08B6/00
Filed: 2000-11-09
Abstract: Disclosed is a skin-contact type terminal system which includes a thermoelectric
module cooling down or heating in accordance with a polarity of current provided
from the skin-contact type terminal with its cooling or heating temperature adjusted
according to a level of a voltage provided thereto, and being controlled to maintain
its cooling or heating operation for a predetermined time, and a control unit for
sensing generation of an alert request signal, supplying the voltage to the
thermoelectric module in accordance with the sensed alert request signal so that the
thermoelectric module cools or heats in accordance with the predetermined cooling
or heating temperature, and controlling the thermoelectric module to maintain its
cooling or heating operation for the predetermined time.
Patent EP-1103295-A2 (EP)
Inventor: YAMAUCHI HAJIME
IPC: B01D43/00
Filed: 2000-11-28
Abstract: An oil component separating apparatus for an oil
containing substance can solve a problem of inflammability and
can separate oil component and solid substance simply at low
cost. The oil component separating apparatus for a oil
containing substance includes a processing vessel having an
injection space, into which a supersonic flow of an overheated
vapor is injected toward an oil containing substance supplied
externally, separating means for separating a evaporated
component and solid component obtained by injection in the
injection space, and condensing means for collecting the oil
component by condensing the evaporated substance.
Patent EP-1111640-A2 (EP)
Inventor: YAMANAKA HIROSHI
IPC: H01H51/22
Filed: 2000-12-18
Abstract: A high frequency relay comprises a contact base block (1) having pairs of
fixed contacts (70), contact members (21) with movable contacts (22), and an electromagnet (3)
for moving the contact members (21) to open and close the fixed contacts (70) by the
movable contacts (22). The contact base block (1) comprises an injection-molded
base having projections on its front surface, first metal films formed as the
fixed contacts on top surfaces of the projections, second metal films formed as
connection terminals for outside devices on a rear surface of the base, each of
which corresponds to one of the first metal films, through holes (16) each having a
conductive material on its inner surface to make an electrical connection
between one of the first metal films and the corresponding second metal film
in the shortest distance, and a third metal film formed on the base to provide
electrical isolation from the first and second metal films, which works as
electromagnetic shield means as well as ground means.
Patent EP-1159961-A2 (EP)
Inventor: DAVIES PETER A J
IPC: C07D333/40
Filed: 1994-03-10
Abstract: The invention provides the use of a compound which has
retinoid like activity and is an agonist of RXR retinoid
receptors, for the manufacture of a medicament for inducing
apoptotic death of tumor cells in a host mammal thereby to
treat the tumor.
Patent EP-1098073-A2 (EP)
Inventor: PFUSTERSCHMID JOHANN
IPC: F01P3/18
Filed: 2000-10-24
Abstract: In a motor vehicle, an oil cooler (12) is disposed
in front of a water-cooler or radiator (3) as seen in the
direction of flow of the cooling medium. To enable an
unimpaired access to the surface of the oil cooler (12)
to be cleaned with a minimum of time and constructional
expenses, the oil cooler (12) is pivotably mounted to one
of the side surfaces (11) of the radiator (3) by means of
a hinge (14, 15) and is pivotable away from said
radiator. The hinge axes (20) is inclined relative to a
vertical line under an angle (21) which is an acute angle
directed forwardly and downwardly relative to the
vertical line.
Patent EP-1046363-A2 (EP)
Inventor: HOWARD ANDREW
IPC: A47B63/00
Filed: 2000-03-20
Abstract: A holder for sheet-form articles designed as a display
stand for leaflets, brochures and the like comprises a rear
support member (12) with two side support members (14, 16)
slidingly movable jointly relative to the rear support member
between extended and retracted positions, thereby to vary the
width of the receiving space for the articles. Preferably,
each rear plate (18) of the side support members (14, 16) is
provided with a generally diagonal slot (32) therethrough,
and studs (34) projecting from the rear support plate (12) are
located within the slots to provide for guided sliding
movement of the parts. As the side support members (14, 16)
move outwards and inwards, so the relative height of the rear
support member (12) increases and decreases respectively.
Patent EP-1039664-A2 (EP)
Inventor: OGATA HIROKI
IPC: A45C13/30
Filed: 2000-03-20
Abstract: It is an object of the present invention to enhance communications functions of a
portable electronic equipment (1) that has optical communications functions so that the
light beams emitted from other equipment with which it communicates can be adequately
received even when the equipment (1) is being carried by a user. According to the present
invention, a light-reflecting member (20) is attached to a strap body (10) used to carry the
portable electronic equipment (1) in a hanging down position. The light-reflecting
member (20) is positioned near a light receiver (4) provided on the top part (1a) of the
portable electronic equipment(1) and reflects light beams used for optical communication
from the surroundings and guides them to the light receiver (4).
Patent EP-1053736-A2 (EP)
Inventor: JONES C THOMAS
IPC: E05F15/10
Filed: 2000-04-10
Abstract: The present invention provides an infant warming apparatus that functions both as an
infant incubator as well as an infant warmer. The apparatus has a heater (12) that moves
vertically with respect to an infant support (14) during the change in function between a
lower position in which it acts as an infant incubator and an upper position (shown in Figure
1) in which it acts as an infant warmer. A powered motive system, such as an electric
motor, powers the movement of the heater (12) between its upper and its lower positions.
The heater (12) also has a door or doors that are open when the heater is at or nearing the
upper position so that the heater can direct energy toward the infant to warm the infant
when acting as an infant warmer. The doors close at or shortly after the heater
commences movement to the lower position. When closed, the doors isolate the heater to
prevent the inadvertent touching of the heater by the infant or attending personnel and
prevents the further radiating of infrared energy towards the infant. The mechanism
operates automatically without any reminder to the user or action by the user. A vent is also
provided in the heater housing that ventilates the housing when the heater (12) is in its
upper position and closes to confine the housing when the heater is in its lower position. A
mechanism automatically closes the vent when the heater moves from its upper position to
its lower position and opens the vent when the heater moves from its lower position to its
upper position. In the preferred embodiment, the vent is biased towards its open position
and the doors are biased towards their open positions.
Patent EP-1047225-A2 (EP)
Inventor: SABAT JOHN JR
IPC: H04L12/28
Filed: 2000-04-20
Abstract: A simple and low cost architecture for coupling
wireless local area network signals between
geographically distributed access points and centrally
located internetworking devices. A cable access point
(CAP) is associated with each respective microcell.
Each CAP includes a remote bridge to convert such
signals to a convenient transport format depending upon
the available cabling. For example, if the available
cabling is a cable television (CATV) plant, the
transport signals are first converted to a T1 format and
up-converted to a carrier frequency suitable for the
CATV plant. Alternatively, the transport signals may be
converted to IEEE 802.3 cable modem signals. If the
available cabling is twisted pair telephone type wiring,
the remote bridge converts the transport signals to a
suitable Digital Subscriber Line (xDSL) format. The
transport signals are collected at a central
distribution or head end access point (HAP). At this
location, a remote bridge then converts the signals from
the up-converted T1 format or the xDSL format, back to
the Ethernet local area network format. These Ethernet
signals are then suitable for coupling to a local area
network hub or other internetworking equipment such as
repeaters, bridges, routers, and gateways.