baber/WOPTO huggingface dataset:
Patent WO-2018118791-A3 (WO)
Title: Nouvelles quinazolinones inhibant la formation d'oligomères tau et leur procédé d'utilisation
Inventor: DAVIDOWITZ ELIOT
IPC: C07D239/90
Filed: 2017-12-18
Abstract: L'invention concerne de nouvelles quinazolinones utiles en tant qu'inhibiteurs de la formation d'oligomères tau, qui se révèlent utiles pour le traitement de maladies neurodégénératives et d'affections apparentées. L'invention concerne également les sels de qualité pharmaceutique desdits composés, des procédés de préparation desdits composés, des intermédiaires utilisés dans la préparation desdits composés et des compositions pharmaceutiques contenant lesdits composés. L'invention concerne en outre des procédés d'utilisation desdits composés, des sels desdits composés et desdites compositions dans le traitement de maladies neurodégénératives et d'affections apparentées.
Patent WO-2018129507-A3 (WO)
Title: Génération d'organoïdes épithéliaux des voies respiratoires à partir de cellules souches pluripotentes humaines
Inventor: KOTTON DARRELL N
IPC: C12N5/071
Filed: 2018-01-09
Abstract: La présente invention concerne une technologie portant sur des procédés et des kits permettant la différenciation dirigée de progéniteurs de poumon NKX2-1+ primordiaux le long de voies de différenciation proximale en cellules épithéliales des voies respiratoires fonctionnelles et organoïdes des voies respiratoires (« bronchosphères ») ou le long de voies de lignée distale à l'aide de la modulation de la signalisation Wnt. D'autres aspects concernent des lignées cellulaires, des procédés, des dosages et des kits comprenant des cellules épithéliales des voies respiratoires, et des dosages permettant de diagnostiquer une maladie qui affecte le gonflement des bronchosphères, et/ou permettant d'évaluer des lésions génétiques et/ou des médicaments pour traiter la maladie, la maladie étant une fibrose kystique. D'autres aspects concernent un médicament personnalisé et des procédés de traitement de la fibrose kystique à l'aide des cellules épithéliales des voies respiratoires.
Patent WO-2019164584-A3 (WO)
Title: Controlling a nuclear reaction
Inventor: LINIK LARRY
IPC: G21C7/22
Filed: 2018-12-28
Abstract: Implementations of a nuclear reactor system include a passive boron injection system operable to release an amount of boron into a containment vessel sufficient to shut down a nuclear fission reaction or maintain the nuclear fission reaction in a sub-critical state. Implementations of a nuclear reactor system include a reactor module that is free of any control rod assemblies. Implementations of a nuclear reactor system include a reactor module that includes a control rod assembly system that is operable to position control rod assemblies in only two discrete positions.
Patent WO-2020160279-A3 (WO)
Inventor: ROBINSON JEREMY
IPC: B68G7/00
Filed: 2020-01-30
Abstract: An upholstered sofa sits in a protective tray with an integrated dust cover. The protective tray attached to a wood frame of the sofa around a frame opening at a dust cover portion of the protective tray. The tray having a separable juncture between an edge portion of the dust cover portion and the portions of the protective tray surrounding the dust cover portion, whereby portions of the tray surrounding the dust cover portion may be removed at a retail sales location or a user's home. The protective tray with the integrated dust cover is semi-rigid and may be attached robotically at the manufacturer's facility.
Patent WO-2021091885-A3 (WO)
Inventor: LIANG SPENCER
IPC: C07K14/47
Filed: 2020-11-03
Abstract: The present disclosure is generally directed to Siglec-9 ECDs and Siglec-9 ECD fusion molecules, and methods of treatment using Siglec-9 ECDs and Siglec-9 ECD fusion molecules.
Patent WO-2021194562-A3 (WO)
Title: Superconductor heterostructures for semiconductor-superconductor hybrid structures
Inventor: GARDNER GEOFFREY C
IPC: H01L39/24
Filed: 2020-11-24
Abstract: A semiconductor-superconductor hybrid structure (10), preferably in form of a nanowire, includes a superconductor heterostructure (14) on a semiconductor layer (12), the superconductor heterostructure including at least a first superconductor layer (14A) on the semiconductor layer and a second superconductor layer (14B) on the first superconductor layer, wherein the first superconductor layer comprises a first superconducting material and the second superconductor layer comprises a second superconducting material that is different from the first superconducting material. By providing multiple layers of different superconducting materials, such as aluminum and lead, the superconducting and physical properties of the superconductor heterostructure can be improved compared to conventional superconducting homostructures, thereby increasing the performance of the semiconductor-superconductor hybrid structure.
Patent WO-2021183786-A3 (WO)
Title: Methods, devices, and compositions for lesion repair and prevention
Inventor: HOH BRIAN
IPC: A61K38/16
Filed: 2021-03-11
Abstract: The present disclosure provides for methods, devices, and compositions for controlling factors involved in the healing of lesions. The methods, devices, and composition include a first therapeutic agent which includes an amount of MCP-1 and/or osteopontin effective to promote recruitment of macrophages to the lesion site. In additional embodiments, there is further provided a second therapeutic agent which includes an inhibitor of at least one of IL-17A, CXCL1, or IL-6 to promote polarization of an amount of the macrophages to M2 phenotype macrophages at the lesion site.
Patent WO-2021243231-A3 (WO)
Inventor: GANTZ JEREMY
IPC: G02B5/26
Filed: 2021-05-28
Abstract: Comme décrit ci-dessus, un ou plusieurs aspects de la présente invention concernent des articles ayant une couleur structurale, et des procédés de fabrication d'articles ayant une couleur structurale. L'article comprend l'élément optique sur sa surface et l'élément optique comprend une ou plusieurs couches (par exemple, une (des) couche(s) réfléchissante(s), une (des) couche(s) constitutive(s) et similaire). L'élément optique peut comprendre une pluralité de parties différentes, chacune des parties différentes ayant une épaisseur relative différente.
Patent WO-2022026642-A3 (WO)
Inventor: BLOBEL GERD
IPC: A61K31/34
Filed: 2021-07-29
Abstract: L'invention concerne des méthodes et des compositions pour produire de l'hémoglobine fœtale et traiter une hémoglobinopathie ou une thalassémie.
Patent WO-2023288019-A3 (WO)
Title: Lipidated peptide inhibitors of interleukin-23 receptor
Inventor: NEELAMKAVIL SANTHOSH
IPC: C07K7/00
Filed: 2022-07-14
Abstract: The present invention relates to novel lipidated peptide inhibitors of the interleukin- 23 receptor (IL-23R) or pharmaceutically acceptable salts, solvates and/or other forms thereof., corresponding pharmaceutical compositions, methods and/or uses of the IL-23R inhibitors for treatment of autoimmune inflammation diseases and/or related disorders. Included are various, highly-customizable peptide sequences to be tailored to treat a broad range of ailments.
Patent WO-2023086592-A3 (WO)
Title: Systems, methods and devices for augmented reality assisted surgery
Inventor: PISSARENKO ANDREI
IPC: A61B34/10
Filed: 2022-11-11
Abstract: Methods and systems are presented herein for augmented reality assisted surgery. Methods and systems include methods and systems for using physical registration objects with a known geometry for registration to determine a reference coordinate system for an augmented reality scene for a surgical setting. Methods and systems include methods and systems for providing an integrated virtual workbench for presenting and sharing patient data in a surgical setting. Methods and systems include methods and systems for providing augmented reality guidance for plate bending for craniomaxillofacial implant surgery.
Patent WO-2023028502-A3 (WO)
Inventor: CHEN RUIQI
IPC: G06F113/10
Filed: 2022-08-24
Abstract: Three-dimensional (3D) lattice objects with multiple zones of different lattice unit cells may be formed by additive manufacturing. Sets of primary unit cells are provided such that each primary unit cell is configured to smoothly transition to other primary unit cells through a series of intermediate unit cells. A universal unit cell may define the primary and intermediate unit cells.
Patent WO-2023147599-A3 (WO)
Title: Electric or hybrid vehicle
Inventor: RUE RICK
IPC: B60W30/02
Filed: 2023-01-31
Abstract: Aspects of the present disclosure relate to an electric or hybrid vehicle. Aspects of the vehicle may be used to provide a variety of functionality, including power exporting and aggregation, power take off functionality, thermal signature reduction, and improved vehicle longevity, vehicle turning, and vehicle control techniques.
Patent WO-2023193025-A3 (WO)
Title: Nouveaux peptides et vaccins permettant de provoquer une immunité protectrice contre le sars-cov-2
Inventor: VELJKOVIC VELJKO
IPC: A61K38/16
Filed: 2023-04-03
Abstract: L'invention concerne de manière générale le développement d'un vaccin permettant de fournir une large protection contre le virus du SARS-CoV-2 ainsi que la production d'anticorps pour traiter la maladie de la COVID-19. Plus particulièrement, l'invention concerne l'utilisation d'un procédé à spectre informationnel (ISM, « informational spectrum method ») pour identifier de nouveaux peptides partageant une homologie structurale et informationnelle avec la sous-unité de protéine spike 1 (SP1) à partir du SARS-CoV-2, ainsi que des vaccins comprenant l'antigène peptidique multi-épitope SP1 qui est capable de déclencher une immunité protectrice contre le SARS-CoV-2. Le vaccin contre le SARS-CoV-2 peut être utilisé seul ou en association avec d'autres vaccins contre la COVID-19.
Patent WO-2023215773-A3 (WO)
Inventor: MILLER CORY G
IPC: C08K5/05
Filed: 2023-05-03
Abstract: An aqueous coating composition that includes a monoalcohol and a diol or polyol, and a compound with urea functionality is disclosed. The aqueous coating composition has less than 250 grams per liter VOC, is capable of being quality application to a variety of substrates at temperatures below freezing (32ºF), being stored for more than 2 weeks below freezing without bulk freezing, and being applied by a variety of usual application techniques (brush, roller, sprayer) at temperatures below freezing. The additives may be added individual during manufacturing of the coating composition or added together to a coating composition as a low temperature additive package.
Patent WO-2013056278-A3 (WO)
Title: Fauteuil roulant
Inventor: WHELAN KEVIN
IPC: A61G5/08
Filed: 2012-10-12
Abstract: L'invention concerne un fauteuil roulant. De manière plus spécifique, cette invention concerne un fauteuil roulant qui peut être plié sensiblement de haut en bas ou dans la direction verticale pour prendre une forme compacte. Ce fauteuil roulant comprend un châssis maintenu sur des roues avant et arrière actionnables, un siège et un dossier. Le siège et le dossier du fauteuil roulant sont montés rotatifs sur le châssis autour d'un axe de rotation commun permettant au siège et au dossier de se plier verticalement l'un sur l'autre et/ou sur le châssis pour prendre une forme compacte. Le siège comprend également des éléments latéraux de siège articulés pour assurer un support latéral à l'utilisateur, ces éléments latéraux de siège articulés pouvant être pliés entre le siège et le dossier lorsque le fauteuil est plié.
Patent AT-501756-A4 (AT)
Title: Exhaust system for internal combustion engine has first and second exhaust pipes, in whose opening area, uniting first and second exhaust pipes span angle at reference points of inner wall of exhaust pipes
Inventor: GLANZ REINHARD DIPL ING
Filed: 2005-05-03
Abstract: An exhaust system (10) has first and second exhaust pipes (11-16) in whose opening area (21-23), the uniting first and second exhaust pipes span an angle less than 30[deg], preferably less than 20[deg]. This angle is spanned by the tangents at reference points of the inner wall (11a-16a) of the exhaust pipes. These reference points are defined by an amount, which is approximately half the diameter of the first and second exhaust pipe, upstream from a first points of intersection of both tangents. The second points of intersection of the two tangents with the inner wall of the second exhaust pipes (15, 16) or the manifold (17) around an amount downstream from the two tangents is provided, which is larger than the diameter (d3) of the second pipe or the manifold. A number of cylinders (1-4) are provided with a preferably one-piece exhaust pipe assembly with at least one first exhaust pipe per cylinder. Two first exhaust pipes of both cylinders, which do not immediately follow one another in the firing order, lead into a second exhaust pipe, and two second exhaust pipes lead into a common manifold. Independent claims are also included for the following: (A) a motor vehicle; (B) a cylinder head; (C) an inlet manifold; and (D) a tensioning device.
Patent BE-1002219-A4 (BE)
Title: Soutien-gorge a bonnets nouveaux.
IPC: A41C3/10
Filed: 1988-10-03
Granted: 1990-10-16
Abstract: Soutien-gorge (10) à deux bonnets (12) comprenant chacun un bonnet intérieur (14) et un bonnet extérieur (16) assemblés à leur périphérie pour former des bords supérieur (20), inférieur (22) et latéraux intérieur (24) et extérieur (26). Le bonnet extérieur (16) est élastique et le bonnet intérieur (14) comprend un segment (60) non élastique s'étendant à partir du bord inférieur (22) et un empiècement (70) élastique entre le haut (68) et les côtés (66) du segment (60) et les bords (20), (24) et (26).
Patent EP-1217299-A4 (EP)
Title: Device and method for feeding fuel
Inventor: HOSHINO TOSHIHUMI
IPC: F23C9/00
Filed: 2000-08-15
Abstract: The present invention provides a fuel feeding apparatus and method for improving the controllability of mixing process and mixing ratio of fuel and combustion air, and a combustion system and method for effecting new combustion properties. The fuel feeding apparatus of the combustion system has fuel feeding means, combustion gas extraction means, steam supply means, mixing means and fuel gas introduction means. The combustion gas extraction means extracts combustion gas of a combustion area therefrom. The mixing means mixes the fuel of fuel feeding means with at least one of combustion gas extracted from the furnace and steam of a steam generator. The fuel gas introduction means introduces a mixed fluid of combustion gas, steam and fuel to the combustion area as a fuel gas, and allows the fuel gas to be mixed with the combustion air. A step of mixing the fuel with the combustion gas after extracted from the furnace and a step of mixing the fuel gas with the combustion air are stepwisely carried out, so that the controllability of mixing process and ratio of the air and fuel is improved. Such a control of fuel gas flow enables control of characteristics of flame and production of flame with new properties in the combustion area. <IMAGE>
Patent EP-1210948-A4 (EP)
Title: Remedies for nervous diseases
Inventor: NISHIKAWA TAKASHIGE
IPC: A61K38/08
Filed: 2000-09-08
Abstract: An agent for treating nerval diseases or an inhibitor of glutamate toxicity (an antidementia agent is not inclusive), which contains as an active component a peptide of the formula of: pGlu-Asn-Ser-Pro-Arg-Gly-NH2 or its pharmacologically acceptable salt.
Patent EP-1266345-A4 (EP)
Title: System for automated screening of security cameras
Inventor: GAROUTTE MAURICE
IPC: G06K9/32
Filed: 2001-02-05
Abstract: The present invention involves a system for automatically screening closed circuit television (CCTV) cameras for large and small scale security systems, as used for example in parking garages. The system includes six primary software elements, each of which performs a unique function within the operation of the security system to provide intelligent camera selection for operators, resulting in a marked decrease of operator fatigue in a CCTV system. Real-time image analysis of video data is performed wherein a single pass of a video frame produces a terrain map which contains parameters indicating the content of the video. Based on the parameters of the terrain map, the system is able to make decisions about which camera an operator should view based on the presence and activity of vehicles and pedestrians, furthermore, discriminating vehicle traffic from pedestrian traffic. The system is compatible with existing CCTV (closed circuit television) systems and is comprised of modular elements to facilitate integration and upgrades.
Patent EP-1195396-A4 (EP)
Title: Aqueous polyurethane gel, process for producing the same, and use thereof
Inventor: ISOZAKI OSAMU
IPC: C08G18/10
Filed: 2001-04-23
Abstract: An aqueous polyurethane gel characterized by being obtained by crosslinking and curing an isocyanate-terminated polyurethane resin (C) which is a product of the reaction of a polyisocyanate (A) with a liquid polyol (B) comprising at least 70 wt.% random copolymer obtained by copolymerizing ethylene oxide (a) with propylene oxide (b) in a weight ratio of from 50/50 to 90/10, in the presence of water in an amount exceeding 9 times by weight the amount of the resin (C).
Patent EP-1281254-A4 (EP)
Inventor: MATCHETT NOEL D
IPC: H04L9/06
Filed: 2001-04-20
Abstract: L'invention concerne un système cryptographique amélioré hautement sécurisé permettant d'effectuer un chiffrement attribuable à un bloc (110) de bits de données à l'aide d'une clé cryptographique (118), ou de générer d'un chiffrement non attribuable à un bloc de bits de données, ledit système cryptographique étant basé sur la norme de cryptage de données traditionnelle, mais utilisant une permutation variable ou une transformation linéaire après la fonction de boîte de substitution. La permutation variable (130) peut s'effectuer dans un réseau de portes programmables par l'utilisateur (FPGA) mettant en oeuvre ladite permutation variable via un réseau de commutation, tel qu'un réseau Oméga ou de Bennes-Waksman, à l'aide d'éléments de commande de réseau de commutation au moyen de la clé cryptographique et d'un mode éligible compatible avec la norme unique de cryptage de données traditionnelle, le triple algorithme de cryptage de données (TDEA), et leurs différents modes, notamment un mode confidentiel dans un ensemble de détenteurs de clé cryptographique commune via un masque de sélection de sous-clé.
Patent EP-1317633-A4 (EP)
Title: Installation tool for installing swage type threaded fasteners
Inventor: FULBRIGHT DAVID J
IPC: F16B19/08
Filed: 2001-08-28
Abstract: A fastener system for multi-piece swage type fasteners, including a pin and a collar, and providing a stump type fastener constructed to be set as a pull type fastener with the fastener pin having a threaded gripping portion and including a compact installation tool having a swage anvil and a rotary threaded member adapted to be threaded onto the threaded pull portion of the pin whereby a relative axial force is applied between the pin and the collar via the rotary threaded member and swage anvil to cause the anvil to radially overengage the collar to swage it into locking grooves on the pin and the pull portion remaining on the pin after installation and with the swage anvil being connected to a piston rod of a piston for axially reciprocating movement for swaging the collar with the rotary threaded member being axially fixed and with the swage anvil and rotary threaded member being offset from the remainder of the tool whereby the tool can be used to install such fasteners in applications of limited clearance.
Patent EP-1378505-A4 (EP)
Inventor: OGAWA TAKANORI
IPC: C07C221/00
Filed: 2002-02-21
Abstract: L'invention concerne un procédé de synthèse totale, pratiquement utilisable, de camptothécine, produit de départ de l'hydrochlorure d'irinotécan et de nombreux dérivés de camptothécine, consistant à produire de la 2'-amino-5'-hydroxypropiophénone, correspondant à l'entité cyclique AB du squelette de la camptothécine, et une cétone tricyclique, correspondant à l'entité cyclique CDE, ce qui permet de produire de la camptothécine et ses dérivés de façon régulière.
Patent EP-1351828-A4 (EP)
Inventor: SMYTHE STEPHEN FRANCIS
IPC: B65D27/34
Filed: 2002-01-04
Abstract: Cette invention concerne une méthode de mise en place d'un contenu dans une enveloppe (5), une technique de traitement du courrier et une ébauche pour enveloppe, qui font intervenir une enveloppe à double utilisation (5). L'enveloppe (5) comporte une bande déchirable (8) sur le rabat de fermeture (7) ce qui permet d'ouvrir l'enveloppe et de la recacheter en prévision d'une seconde utilisation, La mise en place du contenu dans l'enveloppe (5) se fait par une ouverture au bas de cette dernière par rapport à l'information d'adresse (2) lorsque ladite enveloppe est correctement présentée en vue d'une lecture optique ou par machine.
Patent EP-1382032-A4 (EP)
Title: Web-based speech recognition with scripting and semantic objects
Inventor: KROEKER JOHN
IPC: G10L15/00
Filed: 2002-03-14
Abstract: The present invention is a system and method for creating and implementing transactional speech applications (SAs) using Web technologies, without reliance on server-side standard or custom services. A transactional speech application may be any application that requires interpretation of speech in conjunction with a speech recognition (SR) system, such as, for example, consumer survey systems. A speech application in accordance with the present invention is represented within a Web page, as an application script that interprets semantic objects according to a context. Any commonly known scripting language can be used to write the application script, such as Jscript, PerlScript, and VBscript. The present invention is "Web-based" to the extent that it implements Web technologies, but it need not include or access the World Wide Web.
Patent EP-1408823-A4 (EP)
Title: Mobile patient monitor
Inventor: SAPER LAWRENCE
IPC: A61B5/0402
Filed: 2002-07-23
Abstract: A one-way communication mobile patient monitoring system (10) comprising patient transmitters (14), receivers (R1-R4), and a central monitoring station (12). The transmitters (14) analyse a patient's ECG signal and transmit heart rate and rhythm data to the central station (12) via the receivers (R1-R4). The central station (12) alerts hospital staff when vital signs fall outside a preset range.
Patent EP-1436022-A4 (EP)
Inventor: COOPER JOEL D
IPC: A61F2/04
Filed: 2002-09-04
Abstract: La présente invention concerne des dispositifs et des procédés correspondants permettant la modification de l'écoulement gazeux au sein d'un poumon en vue d'améliorer le cycle d'expiration, par exemple, d'un sujet souffrant d'un maladie respiratoire obstructive. Plus particulièrement, des conduits maintiennent des orifices ou des canaux collatéraux à travers la paroi de la voie respiratoire de sorte que l'air puisse passer directement hors du tissu pulmonaire pour à la fois faciliter l'échange d'oxygène et ultérieurement dans le sang et/ou pour la décompression de poumons hyper-gonflés. Les conduits comprennent un tronçon central avec un passage s'étendant à travers le tronçon central. Les conduits comportent en outre une structure de cage distale qui présente un passage et au moins une ouverture en communication fluidique avec le passage du tronçon central. L'invention concerne également des trousses médicales destinées au maintien d'ouvertures collatérales à travers les parois de la voie respiratoire.