baber/WOPTO huggingface dataset:
Patent PT-1051420-E (PT)
Inventor: HIGA TATSUO
IPC: C07D498/22
Filed: 1999-01-27
Abstract: The present invention discloses new cytotoxic tris(oxazole)-containing macrolides having the formula:wherein X represents a lower alkyl; R1 and R2 represent hydrogen or lower alkyl; R3a represents hydrogen, and R3b representsor R3a and R3b together represent oxygen; R4 represents hydrogen, lower alkoxy or lower alkyl; R5 represents hydrogen, carbamoyl, or lower alkanoyl; R6a represents hydrogen, and R6b represents hydroxy, or R6a and R6b together represent oxygen; R7 represents hydrogen, lower alkyl, or hydroxymethyl; R8 represents lower alkoxy or lower alkyl; Y1 represents hydrogen or methyl, and y2 represents hydrogen, or Y1 and Y2 together represent a double bond. Also disclose are methods for treating mammals using the macrolides and pharmaceutical preparations including the macrolides.
Patent PT-1073432-E (PT)
Title: Use of d-serine or d-alanine for treating schizophrenia
Inventor: TSAI GUOCHUAN
IPC: A61K31/198
Filed: 1999-04-14
Abstract: A pharmaceutical composition comprising (i) at least one agonist of the glycine site of an NMDA receptor and (ii) a second therapeutic agent which is a antipsychotic, antidepressant, psychostimulants or Alzheimer's disease therapeutic. The agonist is D-alanine, a salt of D-alanine, an ester of D-alanine, alkylated D-alanine, a precursor of D-alanine, D-serine, a salt of D-serine, an ester of D-serine, alkylated D-serine, a precursor of D-serine, D-cycloserine, a salt of D-cycloserine, an ester of D-cycloserine, a precursor of D-cycloserine, or alkylated D-cycloserine. The pharmaceutical composition is substantially free of D-cycloserine when the agonist is D-alanine, a salt of D-alanine, an ester of D-alanine, an alkylated D-alanine, or a precursor of D-alanine. Where the agonist is D-cycloserine, a salt of D-cycloserine, an ester of D-cycloserine, a precursor of D-cycloserine, or alkylated D-cycloserine, the pharmaceutical composition comprises an amount of the agonist equivalent to 105-500 mg of D-cycloserine.
Patent SG-61190-G (SG)
Title: Compressed absorbent aggregate
IPC: A61F13/20
Filed: 1990-07-21
Abstract: The invention provides a compressed aggregate of superabsorbent and a filler. The aggregate is in the form of tablets or granules and absorbs liquid rapidly. The aggregate may be used in disposable absorbent products, such as diapers, tampons and sanitary napkins, and in containers such as colostomy bags, urinary bags, bedpans and the like.
Patent SG-67987-G (SG)
Title: Absorptive products
IPC: A61L15/00
Filed: 1987-08-19
Abstract: Absorptive products such as a wound dressings, sanitary napkins, incontinence pads or the like comprising an absorbent layer, a porous, water-retardant, embossed fibrous sheet overlying said absorbent layer, and optionally a moisture-permeable cover material at least partially enclosing said absorbent layer and embossed sheet. The product is applied with the embossed sheet opposite the source of fluid to be absorbed and the embossed sheet reduces fluid strike-through to the outer surface of the absorptive product while allowing the product to breathe.
Patent SG-91890-G (SG)
Title: Sole-and-heel structure having premolded bulges
IPC: A43B13/20
Filed: 1990-11-13
Abstract: In one embodiment, the sole-and-heel structure includes an outer member having a sole portion and a heel portion. A bulge is molded into the heel portion and a bulge is molded into the sole portion in the metatarsal region thereof. A thin sealing member is attached to the outer member with adhesive to hermetically seal the cavities defined by the two bulges. A passageway between the two cavities enables air to move back and forth during movement of a person wearing shoes incorporating such sole-and-heel structure.
Patent IE-790133-L (IE)
Title: Metal can lid with push-in opening
IPC: B65D/
Filed: 1979-01-30
Abstract: A metal can lid with a push-in opening device for cans having pressurized contents in which the opening device is formed in the lid from the material of the lid and in which the opening device comprises a panel large enough to be pushed into a can to which the lid is applied by a person's finger pushing downwardly on the panel and in which the panel has a folded periphery which remains with the panel as a reinforcement for the panel against bending of the panel as it is pushed downwardly into the can. A portion of the folded periphery is separated by a line of fracture from the lid, and the lid and panel construction are made to avoid sharp exposed edges.
[US4124139A]
Patent IE-890268-L (IE)
Title: Process for purifying 2-(4-isobutylphenyl)-propionic acid
IPC: C07C51/44
Filed: 1989-01-27
Abstract: 2-(4-Isobutylphenyl)propionic acid is purified by subjecting it to a vacuum rectification in which the temperature is below the decomposition temperature of the acid.
[EP0326027A1]
Patent IE-39069-L (IE)
Title: Former for moulding garments
IPC: A41H5/01
Filed: 1974-03-08
Abstract: 1423393 Moulding garments IMPERIAL CHEMICAL INDUSTRIES Ltd 25 Feb 1974 [20 March 1973] 13301/73 Heading A3V A former for moulding a garment shape from a fabric comprises at least four interconnected tubular members 1-4. Side tubes 5, 6 are also provided. The axes of the tubes define a quadrilateral at the chest plane, a quadrilateral, pentagon or hexagon at the waist plane, and a hexagon at the hip plane. The tubes are slidably arranged on a base 12 around a central pillar 13. The tubes are contoured to the general outline of the human form, and are arranged to conform to an individuals measurements. Tubes 20 at the top of the pillar define the shoulders. To improve the bust shaping short tubes are mounted on spheres at the top of the front tubes 1, 2. Preforms used may be of natural or synthetic e.g. thermoplastic yarns. The former may be moulded by resinous materials or by breaking and reforming chemical bonds within the fibres. The latter may be moulded by heating.
[GB1423393A]
Patent IE-40842-L (IE)
Title: Selective herbicidal composition for beets
IPC: C07D253/06
Filed: 1975-03-19
Abstract: A synergistic mixture of (1) 3-methyl-4-amino-6-phenyl-1,2,4-triazin-5-one and (2) pyrazon or lenacil or benzthiazuron or azolamid plus lenacil or phenmedipham or 2-ethoxy-2,3-dihydro-3,3-dimethyl-5-benzofuranyl methanesulphonate has a particularly broad and selective herbicidal activity in beet crops. Preferably, 0.1-5 parts by weight of (2), in particular 0.1-3 parts by weight, are used per part by weight of (1).
[GB1450365A]
Patent IE-42573-L (IE)
Title: Prosthetic device
IPC: A61F2/00
Filed: 1976-04-21
Abstract: This application describes a shoulder prosthesis having a metal humeral cup component with an extending stem for insertion into the intramedullary canal of the humerus bone. The shoulder or intracancellous component has a ball embraced within the cup between a pair of ultra high molecular weight polyethylene lining inserts, which are locked within the cup under a strong resilient plastic lock ring, which snaps into a circular groove about the rim of the cup. The mouth of the cup and lock ring have mutually engaging bevelled surfaces. The ball and attached scapular component freely pivot or articulate within the cup and lining inserts.
[US3978528A]
Patent FI-831595-L (FI)
Inventor: LAMATTINA JOHN LAWRENCE
IPC: C07D417/14
Filed: 1983-05-09
Abstract: Heretofore unavailable 2-guanidino-4-(2-substituted-amino-4-imidazolyl)thiazoles; a novel process therefor, also advantageous for the preparation of known antiulcer 2-guanidino-4-(2-substituted-amino-4-imidazolyl)thiazoles; intermediate compounds therefor; and a method for treatment of ulcers in mammals therewith.
Patent FI-852235-L (FI)
Inventor: HARRISON PAUL JONATHAN
IPC: A61K9/54
Filed: 1985-06-04
Abstract: A pharmaceutical composition of a medicament, such as a 5-(pyridinyl)-2(IH) pyridone, in sustained release unit dosage form for oral administration. The composition is in the form of beads within a capsule of gelatin or the like. Each bead comprises an inert particulate core having adhered thereto a coating of particles of the medicament. This coating is in turn surrounded by a sustaining coating of three different polymers with different solubility profiles to allow a sustained release of the medicament both in the low pH environment of the stomach and at a higher pH values prevailing in the intestine.
Patent IE-45213-L (IE)
Title: Penicillin compositions
IPC: A61P31/04
Filed: 1977-06-10
Abstract: A class of substituted aminoalkyl esters of methicillin have good oral absorption properties.
[US4285960A]
Patent IE-891190-L (IE)
Title: Sanitary napkin having an attachment system comprising¹biased hinges
IPC: A61F13/56
Filed: 1989-04-13
Abstract: Sanitary napkins are disclosed which include side-protecting flaps (10) having specially designed hinge means (50) for disposing at least one of the flaps (10) in a prefolded, flexible position. The flap or flaps (10) of the preferred embodiments may be wrapped around a crotch portion of an undergarment without additional attachment adhesive.
[EP0337438A1]
Patent IE-41486-L (IE)
Title: Pyridine n-oxide derivatives
IPC: C07D213/89
Filed: 1975-07-04
Abstract: Insecticidally active, novel compounds of the formula I <IMAGE> in which the symbols R1 to R5 are as defined in Claim 1, which are suitable for the selective control of harmful insects, in particular aphids, are prepared by oxidation of the corresponding pyridines. The oxidation is expediently carried out using oxidants such as hydrogen peroxide or peracids.
[GB1454743A]
Patent IE-871578-L (IE)
Title: Integrated logic circuit with output circuit for generating¹an increasing output current limited in time¹increasing output current limited in time
IPC: H03K19/094
Filed: 1987-06-15
Abstract: In integrated logic circuits the problem presents itself that the rapid variation of the (dis-) charging of a data output causes a reverse voltage pulse VL to occur across the inductance formed by the connection wires. The reverse voltage is limited by causing the charge or discharge current Id (for the load capacitances present) to increase linearly to a maximally permissible value. This is done by driving the output field effect transistor TL with a control voltage VC which varies with time according to a square root characteristic.
[EP0250036A1]
Patent IE-901673-L (IE)
Title: Enzymatic removal of a protein amino-terminal sequence
IPC: C07K1/02
Filed: 1990-05-08
Abstract: This disclosure relates to new compounds and to a process for the controlled conversion of such compounds to produce a Protein that comprises an amino acid sequence which is useful as a precursor to human insulin or to a modified human insulin, the amino terminus portion of which sequence does not define a cathepsin C dipeptide removal stop point. The compounds have the formula Met-Y-Protein in which Y is Tyr or Arg.
Patent IE-40315-L (IE)
Title: Surface condenser
IPC: F28B1/02
Filed: 1974-08-12
Abstract: The tubes in the two or more bundles are supported in two or more plates surrounded by a condenser housing comprising a sleeve and plates. Each bundle, its supporting plates and a corresponding portion of the sleeve are self-supporting, and constitute a unit of strength, assembled from a set of blocks. The cavity enclosed by the tubes can accommodate a stiffener beam running in the lengthwise direction of the tubes between the support plates, and between the latter and the tube plates, and attached to the latter by pivot pins.
[FR2241218A7]
Patent IE-861728-L (IE)
Title: Method for producing small spherical polymer particles
IPC: C07K14/76
Filed: 1986-06-27
Abstract: The invention relates to a method of producing small spherical polymer particles from systems containing two liquid phases, the one phase of which contains one or more dissolved substances and is dispersed in the form of small droplets in the other phase to form an emulsion, whereafter the droplets are converted to a solid form. According to the invention the liquid phases used are two mutually immiscible aqueous phases.
Patent IE-781776-L (IE)
Title: Stratified absorbent assembly
IPC: B32B23/02
Filed: 1978-09-04
Abstract: A stratified structure for use as a dressing or for protection against the effects of menstrual periods comprises at least one first layer 1 of cellulose fibres, and a further layer 2 having a base of cellulose fibres the outer surface of which is rendered water- repellent. Preferably both the first and further layers are layers of cellulose fibres, e.g. carding cotton fibres or cellulose fibres derived from dry separated paper pulp. Preferably the first layer is covered with a veil 3 of thermoplastic fibres. The outer surface of the further layer is preferably rendered water-repellent by hot bonding thereof to a polyethylene sheet 4. The invention also provides a method of forming such structures.  (From GB2004812 A) [FR2403186A1]
Patent IE-45875-L (IE)
Title: Heart pacers.
IPC: H03K3/78
Filed: 1977-09-29
Abstract: The stimulation pulse generator (12) of this pacemaker is triggered by a digital computer (10, 11) which determines the pulse interval and the pulse width for the pacemaker pulses transmitted to the heart electrodes via the output terminal (13) by repeatedly running a program. The digital computer comprises a read-only memory (11) with a stored program and a microprocessor (10) which is connected to the stimulation pulse generator (12). The pacemaker can be fully implanted into the body of a patient. <IMAGE>
[GB1587917A]
Patent IE-792083-L (IE)
Title: Piperazino-carbazole derivatives
IPC: C07D403/06
Filed: 1979-10-31
Abstract: This invention is directed to cis-dimethylpiperazines and carbazoles usable for the preparation of 9- [3- (3,5-cis-dimethylpiperazine)propyl]carbazole, salts thereof and solvates of the salts, which are useful in treating aggression and/or psychoses in man and in animals, such as dogs, swine, horses and cattle.
[EP0051321A1]
Patent IE-802544-L (IE)
Title: Cleaning castings.
IPC: B22D31/00
Filed: 1980-12-05
Abstract: For removing and dissolving sand mold residues from cast parts, particularly sand mold residues containing zirconium oxide and titanium oxide, there have previously been used mechanical and electrochemical processes in salt melts. However, these processes are very expensive, attack the surface of the cast pieces or fail to work with sand mold constituents which are difficult to dissolve. These disadvantages are avoided by inserting the cast parts having adhering sand mold residues into a melt of 55 to 97 weight % of alkali metal hydroxide and 3 to 45 weight % of one or more fluorides of an element of the first to third main group of the periodic system of elements and/or zinc at 400 DEG  to 900 DEG  C. Preferably the salt melt additionally contains a boron-oxygen and/or a boron-fluorine compound.
Patent IE-892709-L (IE)
Title: A process for the manufacture of composite cheese
IPC: A01J27/04
Filed: 1989-08-23
Abstract: Soft white cheeses or composite medium-hard cheeses based on previously drained milk curds or rennet are manufactured by means of coextrusion and cutting up into portions of various forms. <??>In the case of medium-hard cheeses, the portions are vacuum packed in a plastic film and then ripened. <??>The products obtained can serve as snacks. <IMAGE> 
[EP0358983A1]
Patent IE-812950-L (IE)
Title: Verification of recorded messages
IPC: G11B27/30
Filed: 1981-12-15
Abstract: PCT No. PCT/AU81/00190 Sec. 371 Date Aug. 10, 1982 Sec. 102(e) Date Aug. 10, 1982 PCT Filed Dec. 16, 1981 PCT Pub. No. WO82/02111 PCT Pub. Date Jun. 24, 1982.The invention provides for the recording of an audio message and subsequent playback thereof and includes a facility for establishing whether the playback message is an authentic reproduction of the original message. The facility is obtained by producing a first data signal indicative of the audio message and recording it together with the audio message and producing a second data signal indicative of the playback message, and comparing the first and the second data signals to establish that the playback is an authentic reproduction of the original message if parity exists between the data signals.
[US4477848A]
Patent IE-883033-L (IE)
Title: Multiple-compression tablet comprising a piperidinoalkanol
IPC: A61K31/445
Filed: 1988-10-06
Abstract: The present invention relates to a pharmaceutical composition in the form of a multiple-compression tablet comprising (a) a discrete zone made with Formulation (A) which comprises a carrier base material combined with a therapeutically effective decongestant amount of a sympathomimetic drug, or a pharmaceutically acceptable salt thereof, the carrier base material being a mixture of (i) one or more pharmaceutically acceptable water-soluble nonionic cellulose ethers in an amount from about 18% to about 50% by weight of Formulation (A), (ii) one or more pharmaceutically acceptable anionic surfactants in an amount from about 2% to about 20% by weight of Formulation (A), and (iii) one or more other pharmaceutically acceptable excipients, and (b) a discrete zone made with Formulation (B) which comprises a second carrier base material combined with a therapeutically effective antihistaminic amount of a piperidinoalkanol, or a pharmaceutically acceptable salt thereof, the second carrier base being a mixture of (i) calcium carbonate in an amount from about 0.5% to about 25% by weight of Formulation (B), (ii) one or more pharmaceutically acceptable nonionic surfactants in an amount from about 1% to about 10% by weight of Formulation (B), and (iii) one or more other pharmaceutically acceptable excipients, wherein Formulation (B) optionally also contains a therapeutically effective decongestant amount of a sympathomimetic drug, or a pharmaceutically acceptable salt thereof; with the proviso that when said pharmaceutical composition is in the form of a compression-coated tablet, the inner core zone is made with Formulation (A) and the outer coat zone is made with Formulation (B).
[EP0311067A1]
Patent NO-813053-L (NO)
Inventor: FISCHER KARL
IPC: H05B3/72
Filed: 1981-09-08
Abstract: An electric hotplate (11) has a metal plate-like or inverted dish-shaped circular hotplate member (12) against whose bottom are pressed by spring elements (25) thin flexible tubular heaters (31), while interposing a multilayer insulation (28). A support disk (26) is placed between insulation (28) and spring elements (25). According to a variant a reinforcement is provided, which may also be placed between the insulation and the tubular heaters. The electric hotplate has a low heat storing capacity and a very flat upper cooking surface (32), even under operating conditions.
Patent NO-820651-L (NO)
Title: Veieanordning.
Inventor: PAERSSON PER-OLOF G
IPC: G01G21/22
Filed: 1982-03-02
Abstract: Veieanordning spesielt beregnet på veiing av last som bæres på en lastpall (35) innbefattende minst en U-formet rammekonstruksjon med to vesentlig horison-tale benpartier (22, 24) som ved den ene ende er forbundet med hverandre ved hjelp av en stegdel (26) og ved den motsatte ende danner en åpning (33) gjennom hvilken en håndteringsanordning for lasten kan innfø-res for å plassere lasten på benpartienes overside. Benpartiene består av et øvre lastbærende element (28) samt et undre element (30) innrettet til å hvile på en underliggende støtteflate, idet belastningsav-- følende organ er anordnet mellom det øvre og undre element for indikering av den last som hviler på det. lastbærende element.
Patent NO-823071-L (NO)
Title: Overvaakningskrets.
Inventor: MALINOWSKI THEODORE SCOTT
IPC: G05B9/02
Filed: 1982-09-10
Abstract: En overvåkningskrets for kontrollsystemet (10) for et kraftverk (14,16) som måler varigheten mellom suksessive kontrollpulser fra en utmatingsport (12a) i en datamaskin (10). I tilfelle noen av kontrollpulsene skulle over-skride det forutbestemte tidsintervallet, sen-der pulskontrollmottakeren.(14,16) et ubrukbart signal gjennom en sperreanordning (13) til buf-fer lagrene i banen for kontrollsignalene. Bufferlagrene overføres da umiddelbart til en blokkert ' tilstand hvor eventuelle etterfølgende kontrollpulser blir hindret i å nå frem til kraftverkets kontrollsystem. En tilbakeføringsknapp (36) vippes over for å nullstille en igangsetteranordning (22) som starter opp igjen programmet i datamaskinen. Et oppstartings-forsinkelsesorgan. (28) sørger for at ingen uønskede kontrollpulser får nå frem til kraftverkets kontrollsystem under en oppvarmingsperiode når de digitale logikkretsene bringes i stand.
Patent NO-855099-L (NO)
Inventor: JEGO GERARD
IPC: H02B11/00
Filed: 1985-12-17
Abstract: A distribution system and column for electric switching apparatus is provided comprising a distribution column with bus bars and a protective case disposed about the bars, a plurality of supports which extend laterally to the case and which have at least one bearing wall applicable to a respective fixing face of the case. Each support is adapted to carry at least one switching apparatus and a current tapping and disconnecting member having clips clippable on the distribution bars through traps provided in a side of the case, said member comprises means for connection to the switching apparatus and a manually actuatable mobile disconnection part.
Patent NO-863286-L (NO)
Inventor: FRANK SYLVAN GERALD
IPC: B01J13/02
Filed: 1986-08-14
Abstract: Process for the formation and the simultaneous encapsulation of small particles of a compound from solution which comprises: (a) dissolving said compound in a first solvent; (b) preparing a solution of encapsulating material and an electrolyte in a second solvent which is miscible with the first solvent and in which the compound to be encapsulated is more or less insoluble, in an amount which is effective, but present in an amount just insufficient to cause coacervation of the encapsulating material without interacting with it; (c) mixing the solutions from step (a) and (b) while stirring to cause the concurrent precipitation of the compound as small particles and formation of a coacervate of the encapsulating material; and (d) gelling the encapsulating material.
Patent NO-900071-L (NO)
Inventor: KENNIS LUDO EDMOND JOSEPHINE
IPC: A61K31/53
Filed: 1990-01-08
Abstract: Novel 2-aminopyrimidinone derivatives of formula <CHEM>  wherein R<1> is <CHEM>  R<3> is hydrogen or C1-6alkyl;  R<4> is hydrogen, C1-6alkyl or substituted C1-6alkyl; R<5> is hydrogen, C1-6alkyl, C1-6alkylaminocarbonyl, Ar-aminocarbonyl, C1-6alkylcarbonyl or Ar-carbonyl; R<6> is hydrogen, C1-6alkyl or Ar-C1-6alkyl; or R<5> and R<6> taken together is -CH2-CH2-, -CH2-CH2-CH2-, -CH=CH-, -CH=N-, -N=CH- or -N=CH-CH2-; the pharmaceutically acceptable acid addition salts and possible stereochemically isomeric forms thereof; pharmaceutical compositions containing such compounds as an active ingredient and methods of preparing said compounds and pharmaceutical compositions.
Patent NO-913628-L (NO)
Inventor: RICHTER JOHAN C F C
IPC: D21C3/02
Filed: 1991-09-13
Abstract: A method of continuously digesting comminuted cellulosic fibrous material (e.g. wood chips) is provided which simultaneously improves uniformity of the end product and has substantial energy economy. The chips are slurried, e.g. with black liquor, and fed to the top of a vertical digester. In the digester the chips are soaked in and heated with black liquor withdrawn from near the bottom of the cooking zone, which black liquor is at cooking temperature. White liquor (kraft cooking liquor) introduced into the cooking zone is preheated by passing it in heat exchange relationship with a portion of the black liquor withdrawn from the digester, so that only a small amount of heat in the form of steam need be added to the white liquor to bring it to cooking temperature. At the top of the digester, a portion of the liquid in the slurry can be withdrawn through a screen, pressurized, and then introduced under pressure with a downward velocity component facilitating a zone of concurrent movement of the chips and liquor.