baber/WOPTO huggingface dataset:
Patent NZ-591185-A (NZ)
Title: Transgenic plants with enhanced growth characteristics comprising a glutamate phenylpyruvate transaminase (GPT) transgene and a glutamate synthetase (GS) transgene
Inventor: UNKEFER PAT J
IPC: A01H5/00
Filed: 2009-08-31
Abstract: Patent No. 591185 Disclosed is a transgenic plant comprising a glutamate pheynylpyruvate transaminase (GPT) transgene and a glutamate synthetase (GS) transgene, wherein GPT transgene and said GS transgene are operably linked to a plant promoter.
Patent NZ-596700-A (NZ)
Title: Compositions, suitable for oral administration, comprising a triazolo [4,5-d]pyrimidin derivate
Inventor: BANKS SIMON
IPC: A61K9/20
Filed: 2007-08-20
Abstract: ABSTRACT - 596700 Discloses a pharmaceutical composition comprising: { 1 S-[1 0, 20, 313 (1 S*,2R*),513]} -3-(7-{ [2-(3,4-difluorophenyl)cyclopropyl]amino} -5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin- 3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol; one or more fillers selected from mannitol, sorbitol, dibasic calcium phosphate dihydrate, dibasic calcium phosphate anhydrate and tribasic calcium phosphate or a mixture thereof; one or more binders selected from alginic acid, carboxymethylcellulose sodium, copovidone and methylcellulose or a mixture thereof; one or more disintegrants selected from croscarmellose sodium and crospovidone or a mixture thereof; and one or more lubricants. The pharmaceutical composition disclosed has a therapeutic application in the treatment of thrombosis associated conditions.
Patent NZ-602954-A (NZ)
Title: Inhibitors of protein tyrosine kinase activity
Inventor: RAEPPEL FRANCK
IPC: A61P27/02
Filed: 2011-04-08
Abstract: Disclosed herein are thieno[3,2-b]pyridine compounds of general formula (I) where the substituents are as defined herein, processes for their preparation, compositions comprising said compounds and uses thereof. Said compounds are protein tyrosine kinase inhibitors and are intended for use for the treatment of ophthalmic diseases such as chorodial angiogenesis, diabetic retinopathy, age-related macular degeneration or retinal edema. Specific examples of the compounds of formula I include 1-cyclopropyl-3-(3-fluoro-4-(2-(5-((4-(2-(2-(2-methoxyethoxy)ethoxy)acetyl)piperazin-1-yl)methyl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)urea and (S)-1-cyclopropyl-3-(4-(2-(5-((4-(2,3-dihydroxypropanoyl)piperazin-1-yl)methyl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorophenyl)urea.
Patent NZ-614359-A (NZ)
Title: Enantiomers of fluconazole analogues containing thieno-[2,3-d]pyrimidin-4(3h)-one moiety as antifungal agents
Inventor: NAWATHYE VIKAS VASANT
IPC: C07D495/04
Filed: 2011-05-31
Abstract: The disclosure relates to enantiomeric fluconazole antifungal compounds of Formula (1a) and Formula (1b) containing a thieno-[2,3-D]pyrimidin-4(3)-one moiety and pharmaceutically acceptable salts thereof The disclosure also relates to method of preparing and isolating these compounds, the use of these compounds in prevention and treatment of fungal infections, and pharmaceutical preparations containing these compounds.
Patent NZ-618593-A (NZ)
Title: A multivitamin/mineral formulation to combat the effects of environmental stress; improve immunity and improve energy while addressing vitamin and mineral deficiencies without the negative side effects of a mega dose nutritional supplement
Inventor: MOHS CHARLES
IPC: A23L33/155
Filed: 2010-01-21
Abstract: A nutritional supplement comprising (1) vitamin 81, vitamin 82, niacin, vitamin B6, biotin and pantothenic acid; and (2) wherein the weight ratio of biotin to vitamin B1 is between 1:20 to 1:25; wherein the weight ratio of biotin to vitamin 82 is between 1:25 to 1:30; wherein the weight ratio of biotin to niacin is between 1:310 to 1:330; wherein the weight ratio of biotin to vitamin 86 is between 1:30 to 1:35; and wherein the weight ratio of biotin to pantothenic acid is between 1:110 to 1:130 and methods of use thereof, are provided that are designed to be effective in optimizing health, improving energy and appearance, reducing the effects of environmental stress and improving, aiding, assisting a person’s immunity, including but not limited to decreasing the instances, duration and severity of cold infections.
Patent NZ-621790-A (NZ)
Title: Cardiovascular therapeutics
Inventor: PEMBERTON CHRISTOPHER JOSEPH
IPC: A61P9/00
Filed: 2012-08-17
Abstract: Disclosed is the use of a pharmaceutical composition comprising a therapeutically effective amount of a Type-B natriuretic signal peptide (BNP-SP) fragment agent and a pharmaceutically acceptable carrier in the manufacture of a medicament for preventing and/or treating a cardiovascular disorder, wherein the Type-B natriuretic signal peptide fragment is an amino acid sequence as defined by a sequence or formula as disclosed in the specification.
Patent NZ-709253-A (NZ)
Title: Chimeric antigen receptors
Inventor: ABBOT STEWART
IPC: C07K14/705
Filed: 2013-12-19
Abstract: Provided herein are therapeutic polypeptides, e.g., chimeric antigen receptors, able to direct an immune cell, e.g., a T lymphocyte to a target antigen, and able to cause the T cell to proliferate or to kill cells displaying the antigen when the antigen binds to the polypeptide, wherein the polypeptides comprise a transmembrane domain from a T cell co-inhibitory protein such as CTLA4 or PD-1. Also provided herein are T lymphocytes expressing the polypeptides, and use of such T lymphocytes to treat diseases such as cancer.
Patent NZ-709716-A (NZ)
Title: A patient interface
Inventor: BENJAMIN WINROW
IPC: A61M16/06
Filed: 2015-07-03
Abstract: A patient interface for delivering breathable gas to a patient, the interface comprising: a mask configured to receive breathable gas; a prong assembly adapted to receive breathable gas, the assembly having at least one prong capable of being fitted inside a patient’s nose and being configured to deliver breathable gas to the patient; and a central link, the central link being adapted to releasably engage with the mask and the prong assembly; the apparatus adapted such that the central link releasably engages with the prong assembly by way of a male-female connection and the apparatus is formed such that when in use the prong assembly is able to releasably engage with the central link which is able to releasably engage with the mask, with the result that the mask
Patent NZ-719724-A (NZ)
Title: Methods of treating antibody-mediated rejection in organ transplant patients with c1-esterase inhibitor
Inventor: BROOM COLIN
IPC: A61P37/00
Filed: 2014-11-21
Abstract: A method for treating or preventing antibody-mediated rejection (AMR) of a transplanted organ comprising administration of a C1 esterase inhibitor (C1-INH) is provided. In particular, the treatment comprises administration according to a dosage regimen consisting of intravenous administration of the C1-INH at a dose of 20,000 units given in divided doses over 10 to 20 days.
Patent NZ-724026-A (NZ)
Title: Tool and tool attachment
Inventor: Graeme Laurence Young
IPC: B25C5/13
Filed: 2015-09-21
Abstract: One problem of some previously proposed tools used for fastening insulators to supports is that it can be difficult to align the tools to an insulator and fire staple legs in the correct holes in the insulator. Disclosed herein is apparatus that comprises an insulator and a tool for fastening the insulator to a support. The insulator comprises an insulator body having a front and a back; a formation for supporting a barrier; and at least one mounting formation having a front and a back by which the insulator is attached to a support, the back of the mounting formation in use being proximal to the support. At least one of the at least one mounting formation comprises one or more passages extending transversely through the mounting formation from the front to the back of the mounting formation. The tool comprises a driver blade for driving a staple; and at least one insulator alignment member. In use, the at least one insulator alignment member aligns one of the one or more passages of the insulator with one leg of a staple, wherein the insulator alignment member allows the insulator to rotate with respect to the tool.
Patent NZ-725866-A (NZ)
Title: A non-caloric sweetener
Inventor: MAO GUOHONG
IPC: C07J17/00
Filed: 2015-05-05
Abstract: Disclosed is a steviol glycoside referred to as rebaudioside D2. Rebaudioside D2 has five β-D-glucosyl units connected to the aglycone steviol. Also disclosed are methods for producing rebaudioside D2, a UDP-glycosyltransferase fusion enzyme, and methods for producing rebaudioside D and rebaudioside E, utilizing a UDP-glycosyltransferase or UDP glycosyltransferase domain comprising an amino acid sequence at least 90% identical to SEQ ID NO: 1.
Patent NZ-735547-A (NZ)
Title: Heart-rate monitoring wearable device for animal
Inventor: TUPIN JOE
IPC: A61B5/11
Filed: 2014-12-29
Abstract: A wearable device for monitoring the health of an animal is described. The wearable device may include one or more sensors whose resultant signal levels may be analysed in the wearable device in order to provide a pet owner, veterinarian, or other party with content useful in monitoring the pet’s overall condition. One or more embodiments include variations of an ultra-wideband (UWB) system to accommodate differences in animals. One or more embodiments include adjusting a sensitivity of a receiver based on a sensor profile corresponding to a breed of the animal. One or more embodiments also relate to the sensor signals being used to determine a heart rate of the animal and adjusting a dynamic window for monitoring the heart rate of the animal based on processing the received signals. The wearable device provides a pet owner and/or a veterinarian with comprehensive information regarding a pet or other animal’s current status such that the pet owner and/or veterinarian may better understand the wellness of a pet through non-invasive remote monitoring in a stable home environment to pick up subtle vital signs indicators that could be precursors to developing health conditions.
Patent NZ-744323-A (NZ)
Title: Compositions comprising 15-hepe and methods of using the same
Inventor: COUGHLAN DAVID
IPC: A61P35/00
Filed: 2016-12-19
Abstract: The present invention generally relates to the use of 15-hydroxyeicosapentaenoic acid (15-HEPE) or a pharmaceutically acceptable derivative thereof for the treatment of an inflammatory disease. In some embodiments, the use of 15-HEPE to treat an inflammatory disease includes administering 15-HEPE to the subject in the fed state to increase absorption of 15-HEPE relative to administering 15-HEPE to a subject in the fasted state.
Patent NZ-775959-A (NZ)
Title: Anti-ctla4 antibodies, antibody fragments, their immunoconjugates and uses thereof
Inventor: SHORT JAY
IPC: A61K47/68
Filed: 2019-10-25
Abstract: A polypeptide having a heavy chain variable region and light chain variable region that specifically binds to CTLA4 protein The disclosed antibodies have higher binding in pH 6.0-6.2, which is typical of the tumour microenvironment, than in pH 7.4, which is typical of a non-tumour microenvironment (pH 7.4). Pharmaceutical compositions and kits comprising the polypeptide or antibodies and antibody fragments containing the polypeptide are also provided.
Patent NZ-779554-A (NZ)
Title: A packaging material and an oral pouched nicotine product
Inventor: BODIN CRISTIAN
IPC: D04H1/58
Filed: 2020-03-16
Abstract: The present invention relates to a packaging material for use in an oral pouched nicotine product in order to enclose a filling material. The filling material comprises a particulate non-tobacco material and a nicotine source. The packaging material is a saliva-permeable nonwoven material comprising carded fibres. 50%-100% of the carded fibres are cellulose-based staple fibres, and 0%-50% of the carded fibres are thermoplastic fibres, with % numbers being based on the total weight of carded fibres at 21°C and 50% RH. The packaging material further comprises a binder, constituting 20%-60% of a total weight of said packaging material. The cellulose-based staple fibres have a linear density less than 1.7 decitex, and the packaging material have a basis weight above 30 g/m2. The present invention also relates to an oral pouched nicotine product comprising such a packaging material.
Patent PT-100029-A (PT)
Title: Process for the preparation of a granular or liquid detergent composition with high activity cellulase and unguent clay
Inventor: CONVENTS ANDRE CHRISTIAN
IPC: C11D3/12
Filed: 1992-01-16
Abstract: A process for the preparation of a granular or liquid detergent composition for washing clothes comprising a surfactant, an adjuvant system and a high activity cellulase in combination with an unguent clay is described. In the detergent composition according to the invention the cellulase comprises a high activity cellulase defined by the C14 CMC method. Preferably the detergent composition comprises from 0.5, 1% or 8% to 50%, 20% or 15% of an unguent clay together with a clay flocculating agent and, in the case of a liquid composition, an antideposition agent for the clay.
Patent PT-101746-A (PT)
Title: Absorbent article of curved shape
Inventor: OSBORN THOMAS WARD III
IPC: A61F13/15
Filed: 1995-07-27
Abstract: An absorbent article, such as a sanitary dressing (Fig. 1). The sanitary dressing of the present invention has a curved configuration which is adapted to the body. The sanitary dressing has a longitudinal profile in which the ends of the profile curve upwards (Fig. 2). The sanitary dressing also has a projection 72 formed by a tuft of fibres with capillary channels on the respective side facing the body. The sanitary dressing also has a curved transverse profile (Fig. 3). <IMAGE>
Patent PT-104382-A (PT)
Title: Dispositivo de extracção para uma máquina de produção de infusões e respectivo mecanismo de contra-pressão
Inventor: PEREIRA JORGE HUMBERTO GOMES
IPC: A47J31/38
Filed: 2009-02-12
Abstract: A INVENÇÃO REFERE-SE A UM DISPOSITIVO DE EXTRACÇÃO PARA UMA MÁQUINA DE PRODUÇÃO DE INFUSÕES A PARTIR DE DOSES DE UM MATERIAL EM PÓ, DESIGNADAMENTE COM APLICAÇÃO EM MÁQUINAS DE CAFÉ EXPRESSO, COMPREENDENDO O DISPOSITIVO UMA PLACA DE EXTRACÇÃO (1) POR EXEMPLO PARA CÁPSULAS, PASTILHAS OU PORÇÕES AVULSAS DE CAFÉ, CUJAS DOSES SÃO SUSCEPTÍVEIS DE SEREM ATRAVESSADAS POR ÁGUA QUENTE SOB PRESSÃO, PARA ASSIM PRODUZIREM BEBIDAS DE INFUSÃO, COMPREENDENDO AINDA UM CALCADOR (2), UM ÊMBOLO (3), UMA TAMPA (4) DO CALCADOR (2), UMA MOLA DE COMPRESSÃO (5), UM SUPORTE (6) DA PLACA DE EXTRACÇÃO, UMA TAMPA DE DISTRIBUIÇÃO (7), VÁLVULAS DE RETENÇÃO (8,10), UM CASQUILHO (12) DA VÁLVULA DE ÁGUA, E EM QUE APÓS INTRODUÇÃO DA CÁPSULA DE CAFÉ (15) NO CENTRO DO MECANISMO DE CONTRA-PRESSÃO, O CALCADOR PRESSIONA A MOLA DE COMPRESSÃO (5) E ESTA, POR SUA VEZ, FAZ CONTRA-PRESSÃO DESCENDENTE SOBRE O CALCADOR (2) PERMITINDO A FIXAÇÃO DA CÁPSULA (15) SOBRE A PLACA DE EXTRACÇÃO (1).
Patent PT-106423-A (PT)
Title: Processo para obtenção de péptidos com efeito anti-hipertensivo a partir de medusas
Inventor: MORAIS ZILDA BRAGA
IPC: A23L33/17
Filed: 2012-07-02
Abstract: PROBLEMAS A RESOLVER 1. OS PROCEDIMENTOS DE OBTENÇÃO DE PÉPTIDOS A PARTIR DE MEDUSAS UTILIZAM O ANIMAL INTEIRO, O QUE LEVA À INCORPORAÇÃO DAS TOXINAS DOS NEMATOCISTOS E PODE CAUSAR EFEITOS TÓXICOS EM HUMANOS, COMOO EFEITO HEMOLÍTICO, SE NÃO SE PROCEDER À SUA SEPARAÇÃO RIGOROSA. 2. A INTENSIDADE DO EFEITO ANTI-HIPERTENSIVO DOS PÉPTIDOS PREVIAMENTE OBTIDOS A PARTIR DE MEDUSAS NÃO ESTÁ DEVIDAMENTE COMPARADA COM A DE FÁRMACOS LARGAMENTE UTILIZADOS COMO, POR EXEMPLO O CAPTOPRIL. SOLUÇÃO 1. APRESENTA-SE UM PROCESSO DE OBTENÇÃO DE PÉPTIDOS A PARTIR DE MEDUSAS QUE É ISENTO DE TOXINAS, POIS A HIDRÓLISE REALIZA-SE APÓS O PRÉ-TRATAMENTO COM REMOÇÃO DAS PARTES QUE CONTÊM NEMATOCISTOS. 2. APRESENTA-SE UM PROCESSO DE OBTENÇÃO DE PÉPTIDOS CUJO EFEITO ANTI-HIPERTENSIVO FOI COMPARADO COM O DO FÁRMACO CAPTOPRIL, TENDO-SE VERIFICADO QUE O FÁRMACO É APROXIMADAMENTE 10 VEZES MAIS POTENTE QUE OS PÉPTIDOS DA MEDUSA. CONTUDO, O FÁRMACO APRESENTA OS EFEITOS SECUNDÁRIOS DO GRUPO SULFIDRILO, QUE OS PÉPTIDOS DA MEDUSA NÃO POSSUEM.
Patent RU-94020367-A (RU)
Inventor: VOLOBUEV A N
IPC: A61N2/00
Filed: 1994-05-25
Abstract: FIELD: medicine. SUBSTANCE: device for magnetic therapy of irritable tissues is provided with an electric stimulator. The electric stimulator brings such tissues in the condition of periodic irritation. The tissues acquire inductive properties, and they become capable of retaining a magnetic field and react on it. EFFECT: higher efficacy of magnetic therapy.
Patent RU-94027137-A (RU)
Inventor: ANISIMOV I G
IPC: A61K9/06
Filed: 1994-07-19
Abstract: FIELD: medicine, pharmacy, lubricants. SUBSTANCE: proposed medicinal Vaseline has 82-86 wt.-% perfume oil and/or medicinal Vaseline and 14-18 wt. -% purified petroleum wax at melting point 59-62 C, kinematic viscosity 7.0-9.0 mm/s at 100 C, color - 4 U, not above, benz(α)pyrene content is 5 mcg/kg, not above. Proposed Vaseline shows increased solubility in chloroform and ether according pharmacopeia classification. Proposed Vaseline can be used in medicinal preparations, creams, ointments, pastes, etc. EFFECT: high quality of product.
Patent RU-94027940-A (RU)
Inventor: ORESHIN M M
IPC: F01N3/10
Filed: 1994-07-25
Abstract: FIELD: engine engineering. SUBSTANCE: porous metal is used as a carrier of the catalyzer. . EFFECT: enhanced efficiency of cleaning. cl, dwg
Patent RU-94032281-A (RU)
Inventor: TIKHONOV E N
IPC: B01D71/36
Filed: 1994-08-25
Abstract: FIELD: ion-exchange membranes. SUBSTANCE: invention focuses on preparing fluorine- containing copolymer with predetermined quality (equivalent weight less than 1000 g/mol) suitable to manufacture ion-exchange membranes with conductivity high enough for electrolysis processes (electrodialysis) Copolymer is prepared through copolymerization of tetrafluoroethylene with 3,6-dioxaperfluoro-(4-methyl-7- octene-sulfonyl fluoride "in bulk" at 0-20 C in presence of free- radical initiator and with periodically replenishing reaction mixture with tetrafluoroethylene. EFFECT: achieved required equivalent weight of copolymer.
Patent RU-94036353-A (RU)
Inventor: CHERNIGOV A V
IPC: E02D17/20
Filed: 1994-09-29
Abstract: FIELD: motor road building in regions with negative mean-year temperature. SUBSTANCE: method for erecting earth bed includes cleaning road path from forest, thick brushes, and moss cover, building lateral water removing ditches, natural thawing out and draining base grounds, ground dumping to the base and reinforcing the ground followed by compacting. Brushes are used to reinforce earth bed. The brushes are laid uniformly on ground surface along all bed length. Then it is impregnated with spent lubricating oil. Then levelling layer is created of sand- gravel mixture, preferentially, of 5 - 7 cm thickness followed by compacting. EFFECT: high reliability.
Patent RU-94036432-A (RU)
Inventor: KOVTUN S N
IPC: A61K6/90
Filed: 1994-09-29
Abstract: FIELD: prosthetic dentistry; particularly, compositions for preparing imprints of teeth, and may be used for preparing imprints in the manufacture of unit-cast fixed, removable lamellar and clasp dentures. SUBSTANCE: composition comprises malleinized polybutadiene, ethoxylated diaminopropane of coconut oil with degree of ethoxylation equal to 15-20, polyethylsiloxane liquid, titanium dioxide, dye and filler. New in the composition is the additional content of synthetic ceresin and copolymer of polybutadiene in the following relation of components, mass parts: malleinized polybutadiene, 100; ethoxylated diaminopropane of coconut oil with degree of ethoxylation equal to 15-20, 39.67-52.89; polyethylsiloxane liquid, 15.72-17.-01; titanium dioxide, 2.80-3.78; dye, 0.08-0.09; filler, 109.10-300.82; synthetic ceresin, 2.36-2.65; copolymer of polybutadiene with styrene, 24.80-66.12. EFFECT: higher practical efficiency.
Patent RU-94037988-A (RU)
Inventor: ROMANOVA JU R
IPC: C12N7/00
Filed: 1994-09-30
Abstract: FIELD: virology, medicine. SUBSTANCE: vaccine strain A/47/Peking/92/3 - reassortant obtained by crossing epidemic virus A/Peking/32/92 (H3N2) with cold-adopted temperature-sensitive virus A/Leningrad/134/47/57 (H2N2) - attenuation donor that is harmless for adult and children and can be used for preparing reassortant vaccine strains from the newly appearing epidemic viruses. Strain A/47/Peking/92/3 is actively propagated in chicken embryos at optimal temperature 32-34 C, shows temperature-sensitivity and cold-adaptation. Reassortant inherited two genes encoding surface proteins (hemagglutinin and neuraminidase) from epidemic virus and six genes encoding nonglycosylated proteins from attenuation donor. Strain A/47/Peking/92/3 (H3N2) is areactogenic for children of age 3-15 years at intranasal administration. EFFECT: preparing vaccine strain corresponding to actual virus A/Peking/32/92 (H2N2).
Patent RU-94043533-A (RU)
Inventor: TERENT EV E G
IPC: G03C1/035
Filed: 1994-12-13
Abstract: FIELD: production of photographic materials. SUBSTANCE: in order to prepare AgBrI monocrystals in a single continuous process from nucleation phase to complete formation of crystal shells, which stimulates more uniform crystal structure, synthesis of silver halide emulsion is conducted in a combined reactor-crystallizer. In this case, first, silver bromoiodide nuclei with maximum silver iodide concentration are formed and then, shells are grown onto the nuclei in which surface silver iodide concentration is gradually lowered to minimum value or to zero. This effect is achieved by smoothly lowering potassium iodide concentration in KI-KBr solution fed into reactor for two-jet crystallization. EFFECT: improved monocrystal structure. 3 cl, 1 dwg
Patent RU-94046003-A (RU)
Inventor: ROBERT EHDVARD BARRELL
IPC: A01N59/16
Filed: 1993-05-19
Abstract: FIELD: medical equipment. SUBSTANCE: coatings are obtained by application of biocompatible metal by the method of precipitation from the vapor phase with the aim of creation of atomic disorder in the coating so that continuous emission of metal ions becomes possible, sufficient to cause an ANTIMICROBIAL action. Preferable conditions of precipitation for creation of atomic disorder are a lower than usual temperature of the backing, and either higher than usual pressure of working medium, or smaller than usual angle of substance flow. ANTIMICROBIAL powders are obtained by mechanical treatment. The invention can be used for other metal and metal powder coatings obtained in a similar way so as to enhance their solubility. EFFECT: facilitated procedure.
Patent RU-95100106-A (RU)
Inventor: DODIN E I
IPC: G01N21/03
Filed: 1995-01-05
Abstract: FIELD: photochemistry, can be used for production of substances with the aid of photosensitized reactions. SUBSTANCE: photochemical reactor has a body of optically transparent material with a layer of sensitizer applied onto its inner surface. EFFECT: improved design.
Patent RU-95101057-A (RU)
Inventor: BEREZOVSKIJ F M
IPC: B05B7/22
Filed: 1995-01-24
Abstract: FIELD: spray coating in metallurgy, mechanical engineering, ship repairing and other branches of industry. SUBSTANCE: electric arc wire metallizer has casing, wire feeding mechanism, electrodes, precombustion chamber and supersonic nozzle rigidly connected with precombustion chamber and adapted to intensify gas flow carrying molten metal particles. Apparatus provides for effective usage of metallizing material (up to 70-80%), production of high-quality coat by increased flow rate of molten metal particles (500-600 m/sec). Coat obtained by means of apparatus has reduced porosity (2-3%). EFFECT: increased efficiency, reduced loss of molten metal particles, improved quality of coat.