baber/WOPTO huggingface dataset:
Patent CA-3101284-A1 (CA)
Inventor: SANKRITHI MITHRA
IPC: F03B15/00
Filed: 2020-12-01
Abstract: ABSTRACT OF THE DISCLOSURE The invention provides a pumped storage system with waterfall control subsystem, architected to enable optimized achievement of two primary goals in the context of a geography with upper and lower water bodies such as lakes, which are connected by a river with a waterfall. The first primary goal comprises energy storage utilizing a pumped storage system between two water bodies of different elevation, which can store energy from excess power production periods and return that energy by producing power to fill needs during deficit power production periods. The second primary goal comprises touristic value & waterfall viewer satisfaction combined with environmental & ecological objectives. A multiobjective control subsystem is utilized for synthesis of time-domain control commands aimed towards optimized achievement of the aforesaid two primary goals, and for control of the pumped storage system with waterfall control subsystem responsive to these time-domain control commands. 1 Date Recue/Date Received 2020-12-01
Patent CA-3101852-A1 (CA)
Title: Retrofit cover plate and assembly to adapt alternative energy supplies to electric water heaters
Inventor: LESAGE CLAUDE
IPC: F24H1/20
Filed: 2020-12-07
Abstract: A multi-functional retrofit cover plate assembly and method for an electric water heater to provide interconnection with an alternative energy system to heat water in a water holding tank of the electric water heater. The cover plate is adapted for replacement connection over a bottom access opening formed in an outer casing of the electric water heater which permits access to a bottom resistive heating element and electrical connections The retrofit cover plate is shaped to define an internal dedicated compartment. A dual resistive heating element is provided for replacement of the bottom resistive heating element. An electronic switch unit is further provided and it has a power cut-off switch for connection to an alternative supply voltage. A  temperature sensor is provided for mounting against an outer surface of the tank of the water heater to feed actual temperature signals of water temperature within the tank, in a lower region thereof, to the electronic switch unit which operates the power cut-off switch upon a predetermined temperature having been attained in the tank of the water heater.  The retrofit cover plate and the assembly also make it possible to covert the water heater to a high temperature water heater or to adapt the electric water heater to a thermal fluid heat source.
Patent CA-3103367-A1 (CA)
Inventor: KHANNA RAJIV
IPC: C12N15/86
Filed: 2019-06-12
Abstract: L'invention concerne des procédés de préparation et de caractérisation de cultures et de préparations de cellules T tueuses.
Patent CA-3111160-A1 (CA)
Inventor: PATEL BIREN
IPC: A61K9/00
Filed: 2019-08-27
Abstract: Des procédés de gestion du poids corporel, d'augmentation de la sensibilité à l'insuline, de promotion de la santé cardiovasculaire et d'augmentation de la quantité de bactéries bénéfiques comprennent l'étape d'exposition d'un sujet à un article contenant du cuivre et leur utilisation pour améliorer la santé corporelle.
Patent CA-3113828-A1 (CA)
Title: Compositions and method for detecting human parvovirus nucleic acid and for detecting hepatitis a virus nucleic acids in single-plex or multiplex assays
Inventor: GAO KUI
IPC: C12Q1/6844
Filed: 2012-07-13
Abstract: Nucleic acid oligomers specific for human parvovirus genomic DNA are disclosed. An assay for amplifying and detecting human parvovirus genotypes 1, 2 and 3 nucleic acid in biological specimens is disclosed. Compositions for amplifying and detecting and detecting the presence of human parvovirus genotypes 1, 2 and 3 genomic DNA in human biological specimens are disclosed.
Patent CA-3118242-A1 (CA)
Title: Nanofiber production apparatus and nanofiber production method
Inventor: IKEGAYA MORIHIKO
IPC: D04H3/016
Filed: 2019-10-09
Abstract: [PROBLEM] To produce nanofiber sheets that are homogeneous over the entire surface of the sheets. Furthermore, to prevent a polymer solution that fails to become nanofibers in a fiber generation device from turning into droplets or small polymer masses that fly straight toward a nanofiber collection device, thereby avoiding directly hitting a nanofiber collecting surface of the nanofiber collection device. [SOLUTION] A nanofiber production apparatus provided with: a nanofiber generation device equipped with a liquid discharge nozzle for discharging a polymer solution in which a polymer has been dissolved in a solvent, and a hot air discharge nozzle for discharging a high-temperature, high-speed gas at high pressure; and a collection device for suctioning and collecting nanofibers generated by the nanofiber generation device. A flow path suppression means is provided between the nanofiber generation device and the nanofiber collection device, said flow path suppression means causing the nanofibers generated by the nanofiber generation device to float so that the flow of nanofibers generated by the nanofiber generation device do not directly fly straight into the nanofiber collection device.
Patent CA-3122962-A1 (CA)
Title: Hydrogen production systems and processes utilizing direct contact steam generation
Inventor: ALLEN JOHN L
IPC: F22G1/12
Filed: 2021-06-23
Abstract: Methods, systems and apparatus for generating high pressure steam and hydrogen - carbon monoxide gas mixtures are provided. Direct contact steam generators (DCSG) are used to produce high pressure superheated steam, partially oxidized hydrocarbons, and combustion gases for use in steam-methane reforming (SMR), partial oxidation (PDX), and combined SMR ¨ PDX auto thermal (ATR) hydrogen production processes.
Patent CA-3123910-A1 (CA)
Inventor: BILLAUD PHILIPPE
IPC: G01S13/78
Filed: 2021-07-07
Abstract: The secondary radar comprising an antenna having a radiation pattern forming a sum channel, designated SUM, a radiation pattern forming a difference channel, designated DIFF, and a pattern forming a control channel, designated CONT, said targets are located by implementing the following steps: -    detecting ADS-B squitters received via said CONT channel (102), via said SUM channel (103) and via said DIFF channel (104); -    measuring at least the power of said squitters and their azimuth with respect to said radar (110); the location of a target transmitting ADS-B squitters being computed by exploiting at least the detection of one ADS-B squitter, in light of the latitudinal and longitudinal position of said radar and of the azimuthal measurement with respect to said radar, the position cell, designated the CPR cell, coded in said squitter being selected via said azimuthal measurement.
Patent CA-3124938-A1 (CA)
Title: Novel compound and pharmaceutical composition comprising same for enhancing anticancer activity
Inventor: PARK KI CHEONG
IPC: A61K31/4985
Filed: 2019-12-27
Abstract: The present invention relates to a novel compound and a pharmaceutical composition comprising same for enhancing anticancer activity, and more specifically, by comprising a compound represented by chemical formula 1 or a pharmaceutically acceptable salt thereof, the anticancer activity of an anticancer agent or radiation can be enhanced, and by suppressing the proliferation of cancer cells and inducing apoptosis thereof, cancer can be treated effectively. [Chemical formula 1] In the chemical formula 1: n is an integer of 0 to 4; R1 is hydrogen, C1-C10 alkyl, or aryl(C1-C4)alkyl; R3 is C1-C6 alkyl, wherein the R3, if a plurality thereof is present, are identical or different from each other; L1 is a direct bond or C1-C6 alkylene; R2 is hydrogen, C1-C10 alkyl, or aryl(C1-C4)alkyl; and R4 is hydrogen, C1-C4 alkyl, C3-C8 cycloalkyl, or aryl(C1-C4)alkyl, or R2 and R4 are connected to each other, forming a 4- to 7-membered ring.
Patent CA-3125081-A1 (CA)
Title: Composition for forming hard coat layer, and eyeglass lens
Inventor: IGAMI Yuka
IPC: C08L83/04
Filed: 2019-12-12
Abstract: The present invention provides a composition for forming a hard coat layer, which is capable of forming a hard coat layer that exhibits excellent adhesion to an adjacent layer, while having excellent hardness. A composition for forming a hard coat layer according to the present invention contains: a (meth)acrylate which has at least one group that is selected from the group consisting of a phosphoric acid group and a sulfonic acid group; a silsesquioxane which has a radically polymerizable group; and metal oxide particles.
Patent CA-3126390-A1 (CA)
Inventor: MCNAMARA MICHAEL T
IPC: G06F11/30
Filed: 2020-01-13
Abstract: Systems include one or more critical datacenter connected to behmd-the-meter flexible datacenters. The critical datacenter is powered by grid power and not necessarily collocated with the flexible datacenters, which are powered "behind the meter". When a computational operation to be performed at the critical datacenter is identified and determined that it can be performed more efficiently or advantageously at a flexible datacenter, the computational operation is instead obtained by the flexible datacenters for performance. The critical datacenter and flexible datacenters preferably share a dedicated communication pathway to enable high-bandwidth, low-latency, secure data transmissions. In some situations, a computational operation is supported by multiple datacenters in a redundant arrangement, such as multiple flexible datacenters.
Patent CA-3128680-A1 (CA)
Title: Methods of improving myocardial performance in fontan patients using udenafil compositions
Inventor: YEAGER JAMES L
IPC: A61P9/00
Filed: 2015-06-30
Abstract: The invention addresses the following needs in the art: (i) improved therapies relating to complications or side effects of the Fontan procedure with the goal of increasing the life span of Fontan patients, and avoiding or delaying the need for cardiac transplantation, and (ii) improved therapies to delay the onset of cardiac failure and/or to improve the quality of life for patients who have had the Fontan procedure. The invention relates to methods of treating, preventing, or minimizing conditions, symptoms, or side effects associated with a subject who has previously had a Fontan procedure. In particular, the methods of the invention are directed to the use of udenafil or a pharmaceutically acceptable salt thereof in single ventricle patients that have undergone the Fontan procedure for the amelioration of associated acute symptoms and chronic symptom development.
Patent CA-3133151-A1 (CA)
Title: Vaccins a arnm
Inventor: DE KOKER STEFAAN
IPC: A61K31/7105
Filed: 2020-03-13
Abstract: La présente invention concerne en général une combinaison de molécules d'ARNm codant pour des protéines immunostimulatrices fonctionnelles et un inhibiteur de la voie de signalisation par CTLA4. En particulier, elle concerne une combinaison d'une ou de plusieurs molécules d'ARNm codant pour au moins une protéine immunostimulatrice fonctionnelle choisie dans la liste comprenant CD40L, CD70 et caTLR4 ; et un inhibiteur de la voie de signalisation par CTLA4, facultativement aussi sous la forme d'une molécule d'ARNm. La présente invention concerne en outre des vaccins comprenant une telle combinaison, ainsi que des utilisations des combinaisons et du vaccin de la présente invention en médecine humaine ou vétérinaire, en particulier dans la prévention et/ou le traitement de troubles prolifératifs cellulaires.
Patent CA-3133607-A1 (CA)
Inventor: SADA YOSHINAO
IPC: A01N43/54
Filed: 2020-01-16
Abstract: Provided is a herbicidal composition comprising a PPO inhibitor and glufosinate or its salt, wherein the weight ratio of the PPO inhibitor to glufosinate or its salt is 1/2,000 or less. The herbicidal composition can effectively control weeds with reduced crop injury.
Patent CA-3138417-A1 (CA)
Title: Systems and methods for autonomous vehicle operation
Inventor: ADAMS ANDRA
IPC: G08G9/02
Filed: 2021-11-09
Abstract: Disclosed herein are systems and methods for autonomous vehicle operation. A  computing system can include a communication device configured to receive a plurality of event signals from at least a first autonomous vehicle that is traversing a path, and a processor in electrical communication with the communication device and configured to determine whether the event signals are indicative of an obstacle in a portion of the path. The communication device can be configured to receive, from at least a second autonomous vehicle, at least one characteristic of the obstacle captured by at least one sensor of the second autonomous vehicle, and transmit, to at least a third autonomous vehicle, at least one task to clear the obstacle from the portion of the path. The processor can be configured to determine, based on the characteristic of the obstacle, the at least one task to be transmitted by the communication device.
Patent CA-3138962-A1 (CA)
Title: A process for the manufacture of (2s,3s,4s,5r,6s)-3,4,5-trihydroxy-6-(((4ar,10ar)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2h-pyran-2-carboxylic acid
Inventor: JUHL MARTIN
IPC: C07D455/06
Filed: 2020-05-19
Abstract: The present invention relates to a process for manufacturing (2S,3S,4S,5R,6S)-3,4,5- trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a- octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid with the formula (Id) below and salts thereof. The compound of formula (Id) is a prodrug of a catecholamine for use in treatment of neurodegenerative diseases and disorders such as Parkinson's Disease. The invention also relates to new intermediates of said process.
Patent CA-3139995-A1 (CA)
Inventor: MICHAILOVSKI ALEXEJ
IPC: B03D1/016
Filed: 2020-06-01
Abstract: The present invention relates to the flotation of non-sulfidic minerals and ores. Particularly the present invention relates to a collector for the beneficiation of non-sulfidic minerals and ores.
Patent CA-3142521-A1 (CA)
Inventor: D'SOUZA SANJAY
IPC: A61P7/06
Filed: 2020-06-17
Abstract: L'invention concerne des procédés de correction d'une mutation dans le gène de la bêta-globine humaine (HBB) dans une cellule ou une population de cellules. L'invention concerne également des procédés d'augmentation de la réparation d'une cassure double brin d'ADN (DSB) dans un gène HBB par la voie de réparation dirigée par homologie (HDR). L'invention concerne également des compositions destinées à être utilisées dans les procédés.
Patent CA-3142838-A1 (CA)
Title: Anti-lrrc25 compositions and methods for modulating myeloid cell inflammatory phenotypes and uses thereof
Inventor: NOVOBRANTSEVA TATIANA I
IPC: C07K16/28
Filed: 2020-06-17
Abstract: The present invention is based, in part, on the discovery of anti-LRRC25 composition ( e.g., monoclonal antibodies and antigen-binding fragments thereof), that regulate inflammatory phenotypes of myeloid cells, such as suppressive myeloid cells, monocytes, macrophages, neutrophils, and/or dendritic cells, including polarization, activation, and/or function, and methods of using such anti-LRRC25 compositions for therapeutic, diagnostic, prognostic, and screening purposes.
Patent CA-3146759-A1 (CA)
Inventor: HU LIANGBING
IPC: H01M4/00
Filed: 2020-08-21
Abstract: An ion-conducting structure comprises a metal-fibril complex formed by one or more elementary nanofibrils. Each elementary nanofibril can be composed of a plurality of cellulose molecular chains with functional groups. Each elementary nanofibril can also have a plurality of metal ions. Each metal ion can act as a coordination center between the functional groups of adjacent cellulose molecular chains so as to form a respective ion transport channel between the cellulose molecular chains. The metal-fibril complex can comprise a plurality of second ions. Each second ion can be disposed within one of the ion transport channels so as to be intercalated between the corresponding cellulose molecular chains. In some embodiments, the metal-fibril complex is formed as a solid-state structure.
Patent CA-3148670-A1 (CA)
Title: Electrical discharge process and apparatus for machining elongated workpieces
Inventor: ARCIONI MASSIMO
IPC: B23H11/00
Filed: 2020-08-31
Abstract: An apparatus for electrical discharge machining process is disclosed. The apparatus comprises adjustable supports (4), up-on which an elongated workpiece (5) to be machined can be placed and rotated. The adjustable support (4) allows to adjust the position of the workpiece (5) with respect to a base plate (31). The apparatus further comprises a rotating member (6), adapted to grip one end of the elongated workpiece (5) to be machined and rotate it around its longitudinal axis (R). Also disclosed are a method for machining rotor and a monolithic shaft-impeller rotor.
Patent CA-3149369-A1 (CA)
Inventor: COMBE JONATHAN D
IPC: A61B17/00
Filed: 2020-09-23
Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems, and methods that include tissue anchors such as for chordae tendineae repair.
Patent CA-3149621-A1 (CA)
Title: Pd-l1 binding molecules comprising shiga toxin a subunit scaffolds
Inventor: POMA ERIC
IPC: A61P35/00
Filed: 2020-09-18
Abstract: Provided herein are PD-L1 binding molecules comprising or conjugated to a toxin, e.g. a Shiga toxin A Subunit derived polypeptide. In some embodiments, the PD-L1 binding molecules are cytotoxic. In some embodiments, the PD-L1 binding molecules are capable of delivering a CD8+ T-cell epitope to an MHC class molecule inside a PD-L1 positive cell. The PD-L1 binding molecules described herein have uses for selectively killing specific cells (e.g., PD-L1 positive tumor cells and/or immune cells); for selectively delivering cargos to specific cells (e.g., PD-L1 positive tumor cells or immune cells), and as therapeutic and/or diagnostic molecules for treating and diagnosing a variety of conditions, including cancers and tumors involving PD-L1 expressing cells (e.g., PD-L1 positive tumor cells or immune cells).
Patent CA-3150602-A1 (CA)
Title: Hockey goalkeeper leg pad
Inventor: OUELLET FRANCIS
IPC: A41D13/05
Filed: 2020-08-14
Abstract: A hockey goalkeeper leg pad includes a core, a skin covering the core, a lateral leg flap and a medial leg flap defining a leg channel, and a lacing member. The lacing member includes lower tabs and upper tabs. The lower tabs and the upper tabs each defining apertures with a front inner surface of the skin covering the core, and the lower tabs and the upper tabs being attached to the front inner surface at lateral outer ends thereof. The upper tabs are laterally offset outward of the lower tabs relative to a longitudinal centerline of the lacing member. A lace extends through the lower apertures and the upper apertures, as well as through the core to secure the core to the lacing member.
Patent CA-3152975-A1 (CA)
Title: Lubricating oil compositions
Inventor: CHOMMELOUX CLAIRE
IPC: C10M135/02
Filed: 2020-09-03
Abstract: The present disclosure generally relates to a lubricating oil composition comprising: a major amount of an oil of lubricating viscosity, one or more detergents comprising at least one alkylhydroxybenzoate compound, and an ashless sulfur compound. Also provided is a method of lubricating an engine with said lubricating oil composition.
Patent CA-3158427-A1 (CA)
Title: Door lock assembly
Inventor: LEITES RICK
IPC: E05B63/04
Filed: 2022-05-04
Abstract: A door lock system includes a toolless handing assembly that selectively sets a handle in a left or right home position. The handing assembly may cooperate with a disc and a spring that biases the disc to a default position. The disc may be rotated in a first direction to set the disc in a first home position. A catch may engage the disc to retain the disc in the first home position. The catch may be released to return the disc to the default position and the disc may be rotated in a second direction to set the disc in a second home position, opposite the first home position.
Patent CA-3159083-A1 (CA)
Title: Variants d'alpha-amylase
Inventor: ANDERSEN CARSTEN
IPC: C12N9/28
Filed: 2020-12-18
Abstract: La présente invention concerne des variants d'alpha-amylase d'une alpha-amylase parente présentant des performances de lavage améliorées par rapport à l'alpha-amylase parente. La présente invention concerne également des polynucléotides codant les variants, des constructions d'acide nucléique, des vecteurs et des cellules hôtes comprenant les polynucléotides, et un procédé de production des variants de la présente invention.
Patent CA-3160758-A1 (CA)
Inventor: EKSTRAND PER
IPC: G10L19/02
Filed: 2010-02-17
Abstract: Signal processing devices and methods filter and process an audio signal. A  signal processing device includes a high frequency reconstructor or a parametric stereo processor that generates modified complex-valued subband sample; and a synthesis filter bank that receives the modified complex-valued subband samples and generates time domain output audio samples. The analysis filter bank comprises analysis filters (h k(n)) and the synthesis filter bank comprises synthesis filters (f k(n)) that are complex exponential modulated versions of a prototype filter (p0(n)) that has a length N. The analysis filter bank and synthesis filter bank have a system delay of D samples, wherein D is smaller than N. This structure can provide a reduced overall delay.
Patent CA-3160865-A1 (CA)
Title: Blood treatment systems
Inventor: FINI MASSIMO EARL
IPC: A61M1/34
Filed: 2020-11-04
Abstract: Dialyzer systems can consolidate multiple technologies and functionalities of blood treatment systems in a significantly integrated fashion. For example, this disclosure describes dialyzer systems that include a magnetically driven and magnetically levitating pump rotor integrated into the dialyzer. Such a dialyzer can be used with treatment modules that include a magnetic field-generating pump drive unit. In some embodiments, the dialyzers include pressure sensor chambers with flexible membranes with which corresponding pressure transducers of the treatment modules can interface to detect arterial and/or venous pressures.
Patent CA-3161844-A1 (CA)
Inventor: ONUOHA SHIMOBI
IPC: C07K16/30
Filed: 2020-12-18
Abstract: The present disclosure relates to antigen-binding domains which bind the antigen prostate-specific membrane antigen (PSMA) and to chimeric antigen receptors (CARs) which comprise such antigen binding domains.
Patent CA-3162239-A1 (CA)
Title: Systemes et dispositifs de preparation d'echantillons et de detection d'analytes
Inventor: BHARGAVA KRISNA C
IPC: C12Q1/6844
Filed: 2020-11-20
Abstract: L'invention concerne des systèmes et des procédés de préparation d'échantillons et de détection d'analytes.
Patent CA-3163848-A1 (CA)
Title: Composition for preventing or treating macular degeneration, containing cell permeable nucleic acid complex as active ingredient
Inventor: LEE DONG IN
IPC: A61K47/64
Filed: 2021-01-06
Abstract: The present invention relates to a composition for preventing or treating macular degeneration, containing a cell permeable nucleic acid complex as an active ingredient and, more specifically, to a pharmaceutical composition for preventing, ameliorating, or treating macular degeneration comprising, a cell-permeable nucleic acid complex containing a bioactive nucleic acid targeting an NLRP3 gene; and a carrier peptide nucleic acid which are complementarily bound to said bioactive nucleic acid, as an active ingredient. The cell permeable nucleic acid complex, in which the bioactive nucleic acid targeting the NLRP3 gene and the carrier peptide nucleic acid are complementarily bound to each other, according to the present invention, has high cell permeability and thus inhibits the expression of NLRP3 without direct injection, and thereby is useful for preventing, ameliorating, or treating macular degeneration.