baber/WOPTO huggingface dataset:
Patent NZ-197008-A (NZ)
Title: Acylanilide derivatives and pharmaceutical compositions
Inventor: CROSSLEY N S
IPC: C07C237/42
Filed: 1981-05-05
Abstract: Novel 3,4-disubstituted-N-acylanilines of the formula:  <IMAGE> wherein R1, R2 and ring A are defined in claim 1; wherein R3 is hydrogen or alkyl of up to 4 carbon atoms, or is joined to R5 as stated below; wherein R4 is alkyl of 2 to 4 carbon atoms, or has the formula -CX1X2X3 wherein X1, X2 and X3, which may be the same or different, each is hydrogen, fluorine or chlorine; wherein R5 is hydrogen, hydroxy or alkoxy or acyloxy each of up to 15 carbon atoms, or is joined to R3 to form an oxycarbonyl group such that together with the  <IMAGE>  part of the molecule it forms an oxazolidinedione group; and wherein R6 is hydrogen or halogen. These compounds possess antiandrogenic activity and are useful for the treatment of androgen dependent or prostatic diseases. Representative of the compounds is 3,4-dichloro-N-(2-hydroxy-2-p-nitrophenylpropionyl)aniline. Also disclosed are processes for the manufacture of the compounds and pharmaceutical and veterinary compositions containing them.
Patent NZ-200922-A (NZ)
Title: Liquid impregnated cleaning cloth with barrier patterns spaced by at least 8mm
Inventor: DEACON M J
IPC: A47K10/16
Filed: 1982-06-11
Abstract: In an article suitable for wiping surfaces which comprises an elongate web substrate impregnated with a liquid composition, migration of the liquid along the length of the substrate is substantially prevented by dividing the substrate into a plurality of individual areas by means of a repeating pattern of liquid- repellent barrier material, for example, wax or certain resins, extending across the whole width of the substrate. This measure prevents fluid loss by capillary action and evaporation when the wet substrate is stored in a dispenser. The wet substrate is preferably used in conjunction with a dispenser having a relatively tight closure, especially one in which the closure is formed by two resilient diaphragms with out-of-register apertures. The wet substrate delivery system may be used, for example, for hand hygiene in hospitals, washrooms or kitchens.
Patent NZ-208521-A (NZ)
Title: Leucine derivatives and pharmaceutical compositions
Inventor: HADVARY P
IPC: C07D305/12
Filed: 1984-06-15
Abstract: Novel compounds of the formula    <IMAGE>  I  wherein A signifies the group   <IMAGE>  or -(CH2)5-, which inhibit pancreas lipase and can be used for the control or prevention of obesity and hyperlipaemia, are disclosed. The inventive compounds can be produced by the cultivation of microorganism Streptomyces toxytricini, identified as NRRL 15443.
Patent NZ-216545-A (NZ)
Title: Ergoline derivatives and pharmaceutical compositions
Inventor: BERNARDI L
IPC: C07D457/02
Filed: 1986-06-16
Abstract: Ergoline derivatives of the formula Iwherein R<sub>1</sub>=H, CH<sub>3</sub>; R<sub>2</sub>=H, halogen, CH<sub>3</sub>, CN, C<sub>1</sub>-C<sub>4</sub> alkylthio or phenylthio; R<sub>3</sub>=C<sub>1</sub>-C<sub>4</sub> hydrocarbon; R<sub>4</sub>=H, OCH<sub>3</sub>; R<sub>5</sub>=H and R<sub>6</sub>=-CH=CH-CONHR<sub>7</sub> or R<sub>5</sub> + R<sub>6=</sub> =CH-CONHR<sub>7</sub>; R<sub>7=</sub> 2-thiazolyl, 3-pyridazinyl, 1,3,4-thiadiazol-2-yl or 4-pyrimidinyl group optionally substituted, and pharmaceutically acceptable salts thereof, display activity on the Central Nervous System and are useful as antiprolactinic agents. Their preparation, pharmaceutical compositions containing them, and their use in the preparation of a medicament for the treatment of Parkinson's disease are also described.
Patent NZ-221294-A (NZ)
Title: Process for preparing isothiazolones via 3-mercaptopropionamide precursors
Inventor: CHANG SOU-JEN
IPC: C07C319/00
Filed: 1987-07-31
Abstract: In the manufacture of a compound of the formula: <CHEM>  (a) a mixture of a compound of the formula: <CHEM> and an alcohol or an equivalent thereof and (b) strong inorganic acid, are cofed optionally to an appropriate solvent; wherein X is hydrogen, alkyl, alkenyl or aryl and R is optionally substituted secondary alkyl, tertiary alkyl or aralkyl. The compound so made can be treated with a thiolating agent to form an N-substituted-3-mercaptopropionamide which in turn can be halogenated to an isothiazolone biocide.
Patent NZ-233647-A (NZ)
Title: P-(fluoro)methyl aminopropylphosphinic acid derivatives and pharmaceutical compositions
Inventor: HALL ROGER GRAHAM
IPC: A61P25/04
Filed: 1990-05-11
Abstract: P-substituted aminoalkylphosphinic acids of the formula <CHEM> wherein R denotes an optionally fluorinated methyl group, R1 denotes hydrogen, lower alkyl, lower alkoxy, hydroxy, halogen or a fluorinated methyl group and R2 and R3 denote hydrogen or R2 denotes hydroxy, lower alkoxy or halogen and R3 is hydrogen or R2 and R3 together represent an oxo group, and their pharmaceutically acceptable salts are active as GABAB agonists and can be used in the treatment of spinal spasticity, multiple sclerosis and cerebral palsy, trigeminus neuralgia, drug withdrawal syndromes and/or conditions of pain. They can be manufactured by methods known per se and suitable such methods are described.
Patent NZ-235776-A (NZ)
Title: Substituted 5-((tetrazolyl)alkenyl) imidazoles and pharmaceutical compositions
Inventor: KEENAN RICHARD MCCULLOCH
IPC: C07D405/14
Filed: 1990-10-23
Abstract: Angiotensin II receptor antagonists having the formula: <CHEM> which are useful in regulating hypertension and in the treatment of congestive heart failure, renal failure, and glaucoma, pharmaceutical compositions including these antagonists, and methods of using these compounds to produce angiotensin II receptor antagonism in mammals.
Patent NZ-237740-A (NZ)
Title: Recombinant polypeptide immunoreactive with sera from hepatitis c patients, kit for diagnosis assay, expression system, and polynucleotides
Inventor: REYES GREGORY
IPC: G01N33/576
Filed: 1991-04-08
Abstract: Peptide antigens which are immunoreactive with sera from individuals infected with hepatitis C virus (HCV) are disclosed. Several of the antigens are immunologically reactive with antibodies present in individuals identified as having chronic and acute HCV infection. The antigens are useful in diagnostic methods for detecting HCV infection in humans. Also disclosed are corresponding genomic-fragment clones containing polynucleotides encoding the open reading frame sequences for the antigenic peptides.
Patent NZ-243437-A (NZ)
Title: Conjugate for use in anti-tumour therapy comprising a toxin moiety and a target cell binding moiety
Inventor: WRIGHT ANDREW FIRMAN
IPC: A61K47/48
Filed: 1992-07-03
Abstract: Conjugates useful for treating gastrointestinal tumours such as colorectal tumours comprises an antibody such as C242 antibody and a toxin such as ricin A. The antibody and toxin may be coupled by a linker. Pharmaceutical compositions containing the conjugates and processes for their preparation are also inculded as well as methods of treating gastrointestinal tumours.
Patent NZ-255538-A (NZ)
Title: Refrigerator cabinet; central portion of panel spaced outwards from periphery to give increased insulation thickness
Inventor: GRANT ALEXANDER
IPC: F25D23/06
Filed: 1993-09-09
Abstract: PCT No. PCT/GB93/01904 Sec. 371 Date May 3, 1995 Sec. 102(e) Date May 3, 1995 PCT Filed Sep. 9, 1993 PCT Pub. No. WO94/07097 PCT Pub. Date Mar. 31, 1994A temperature-controlled cabinets, particularly, refrigerators, freezers, fridge-freezers and drinks coolers (chillers) which, in order to overcome the problem of inferior insulative properties of alternative polyurethane foams used to reduce the emission of CFC's during injection and setting of foamed polyurethane, provides a cabinet within which a controllable stable temperature may be maintained. This cabinet includes an inner container (25a), an outer shell (10a), and a thermally insulating material (45a) sandwiched therebetween, wherein at least a portion of a front side (50a) of the outer shell (10a) has a panel (85a) which is displaced outwardly from the rest of the front side (50a) of the outer shell (10a). In a preferred embodiment, the cabinet forms a chest freezer (5a).
Patent NZ-262284-A (NZ)
Title: Bactericidal/permeability-increasing protein analogues and their production, coding sequences and compositions thereof
Inventor: THEOFAN GEORGIA
IPC: C12N5/02
Filed: 1994-02-02
Abstract: Disclosed are novel bactericidal/permeability-increasing (BPI) protein products wherein cysteine residue number 132 or 135 is replaced by another amino acid residue, preferably an alanine or serine residue and/or wherein the leucine residue at position 193 is the carboxy terminal residue. Also disclosed are DNA sequences encoding methods for the production of the same in appropriate host cells, and stable homogeneous pharmaceutical compositions containing the analogs suitable for use in treatment of gram negative bacterial infection and its sequelae.
Patent NZ-286688-A (NZ)
Title: Snips: moulded pivot integral with one member engages with metal blade on other member
Inventor: LINDEN ERKKI OLAVI
IPC: B29C45/14
Filed: 1996-05-29
Abstract: A pair of snips including first and second, opposed, elongated members (12,14), each member comprising a jaw (24,36) at a front end portion thereof, a handle (32,34) at a rear end portion thereof, and a midportion (28) where the members (12,14) cross over each other. A pivot (16) unites the midportions for scissor-like movement of the handles (32,34) and jaws (24,36) about the pivot (16). The snips also includes a gripper (52) biasely connected to the handle (32) of one of the members to retain a portion of a workpiece (W) severed by the snips. The first member (12) includes a metal plate (18) having a forwardly extending blade (24) which comprises one of the jaws and a rearwardly extending tang (26). According to the invention, at least the handle (32) of the first member (12) and gripper (52) are made of a moldable material molded onto the metal plate (18), such that the handle (32) of the first member (12) is molded onto the tang (26) of the metal plate (18) and the gripper (52) is integral with the first member (12) and molded onto an outer surface of the plate (18). The moldable material is most preferably a plastic, but other moldable substances could be employed.
Patent NZ-297401-A (NZ)
Title: Caprolactam preparation by decomposition of oligomers or polymers in the fluid phase in the presence of a catalyst and a solvent
Inventor: FUCHS EBERHARD
IPC: C07D201/12
Filed: 1995-11-22
Abstract: Caprolactam is prepared by cleaving oligomers or polymers containing essentially the repeating unit -[-N(H)-(CH2)5-C(O)-]- in the presence of a catalyst at elevated temperatures by a process in which the cleavage is carried out in the liquid phase in the presence of a heterogeneous catalyst and of an organic solvent.
Patent NZ-312916-A (NZ)
Title: Package with 3 dimension design, film with design inserted into transparent container that has a complementary design on its surface
Inventor: HAUGK PETER
IPC: B65D23/14
Filed: 1996-07-10
Abstract: A container has a label or decoration in the container and unattached to any interior surface. The label or decoration is in the form of a monolayer film or a laminate film with the decoration and other materials under a coating or within the laminate layers. A preferred mode is for the container to be a pump container having a constricted opening. The film will be of an elliptical to a rectangular shape. If rectangular the film will have rounded lower edges or a parabolic lower portion for ease of insertion into container openings. The container preferably will have grooves, projections or other techniques for stabilizing the film in the container. Monolayer films will have the decoration printed onto the surface and will have a protective coating over this surface. Laminate films can be of the same or dissimilar films with the printed surface between the laminate films. The useful adhesives for the films are those that are not affected by the product in the container. These include pressure sensitive adhesives, heat cured adhesives, catalytically cured adhesives, ultraviolet light cured adhesives and electron beam cured adhesives.
Patent NZ-335051-A (NZ)
Title: Heart volume limiting device
Inventor: ALFERNESS CLIFTON A
IPC: A61M60/857
Filed: 1997-10-01
Abstract: The present disclosure is directed to a cardiac reinforcement device (CRD) for the treatment of cardiomyopathy. The CRD provides for reinforcement of the walls of the heart by constraining cardiac expansion, beyond a predetermined limit, during diastolic expansion of the heart. The CRD is conically shaped and is applied to an epicardial surface of the heart to locally constrain expansion of the cardiac wall during diastole without assisting systolic function.
Patent NZ-337059-A (NZ)
Title: Glaucoma drain implanting device comprising a nozzle and plunger
Inventor: FEINGOLD VLADIMIR
IPC: A61F2/04
Filed: 1998-02-27
Abstract: A glaucoma drain implanting device having a body portion including a proximal end and a distal end, a separate nozzle portion connected to the distal end of the body and including a drain delivery passageway, a plunger having a plunger tip movably disposed relative to the drain delivery passageway, and a drain receiver. A method of using the drain implant device includes the steps of advancing a glaucoma drain into the drain delivery passageway of the device, thereby placing the glaucoma drain in a staged configuration, and, placing an exit of the drain delivery passageway proximately to the eye and further advancing the glaucoma drain to cause the glaucoma drain to pass through the exit of the drain delivery passageway and into the tissue of the eye.
Patent NZ-501275-A (NZ)
Title: 2-substituted 4,5-diaryl imidazoles
Inventor: REVESZ LASZLO
IPC: A61K31/4545
Filed: 1998-06-26
Abstract: Provided are 2-substituted 4,5-diaryl imidazoles, in particular compounds of Formula I wherein R1, R2, R3 and R4 are as defined, in free or pharmaceutically-acceptable acid addition salt or physiologically-cleavable ester form, which have p38 MAP kinase (Mitogen Activated Protein Kinase) inhibiting activity.  The compounds are used as pharmaceuticals for treating TNFa and IL-1 mediated diseases such as rheumatoid arthritis and diseases of bone metabolism, such as osteoporosis; R1 is 4-pyridyl, which is optionally substituted with one or two substituents each of which is independently selected from C1-4alkyl, halogen, C1-4alkoxy, C1-4alkylthio, NR5R6, wherein R5 and R6 is each independently C1-4alkyl; R2 is phenyl, naphth-1-yl or naphth-2-yl, which is optionally substituted by up to 5 substituents; R3 is hydrogen, R4 is optionally substituted pyridyl; in free or pharmaceutically acceptable addition salts or physiologically-cleavable ester form provided that R2 is not phenyl substituted with a radical selected from alkylsulfonyl or aminosulfonyl.
Patent NZ-505416-A (NZ)
Title: Bacteriocide compositions containing iminoctadine tris (albesilate) and fenhexamid for agricultural and horticultural use
Inventor: URIHARA ICHIROU
IPC: A01N47/44
Filed: 1999-11-01
Abstract: Agricultural and horticultural fungicidal compositions containing as active ingredients combinations of I) 1,1'-iminiodi(octamethylene)diguanidine represented by formula (I) or an acid addition salt thereof and II) 1,1'-iminiodi(octamethylene)diguanidine represented by the formula (II) are described.
Patent NZ-505939-A (NZ)
Title: Aerator with pump and venturi, with air inlet pipe being adjustably fixed to float(s)
Inventor: EDWARDS NORMAN ALUN LINDSAY
IPC: B01F13/00
Filed: 1999-01-27
Abstract: Disclosed is an aerator (10) that includes a venturi chamber (not shown), a pump for drawing liquid into the venturi chamber from a liquid inlet, an air inlet connected to the venturi chamber for aerating the liquid drawn through the venturi chamber, and an outlet for discharging the aerated liquid. A float chamber (26) is provided for supporting the aerator in a liquid medium, e.g. a fishing lake. Preferably, the liquid inlet and the outlet are on substantially parallel axes, wherein the liquid inlet is turnable between two positions: one position where the liquid inlet takes in liquid in an opposite direction to the outlet flow and the other position where the liquid is drawn in and discharged in the same direction. A control means responsive to sensors for determining biological oxygen demand and chemical oxygen demand is also provided for controlling the speed of the pump
Patent NZ-513161-A (NZ)
Title: Methods and compositions for healing and repair of articular cartilage
Inventor: ZHANG RENWEN
IPC: A61L27/38
Filed: 2000-01-31
Abstract: An osteochondral graft comprising an effective  amount of  bone morphogenetic protein (BMP) to stimulate osteogenic activity    of    infiltrating    progenitor    cells    for administration  to  an area in need of  articular  cartilage regeneration.
Patent NZ-516438-A (NZ)
Title: Method of producing a diffractive structure in security documents
Inventor: ZIENTEK PAUL
IPC: B44F1/12
Filed: 2000-06-27
Abstract: A method of producing a security document or device comprising a substrate and an optically diffractive device, the method comprising the step of: irradiating an area of the substrate (2) on one surface with patterned laser radiation to ablate selected portions of the surface and thereby form an optically diffractive structure in the one surface. A method of producing a security document or device comprising a substrate and an optically variable device, such as a means for creating polarisation patterns, the method comprising the step of: exposing an area of the substrate on one surface to a light source which causes photo-polymerisation of the substrate which in turn produces a polarisation state or pattern.
Patent NZ-528600-A (NZ)
Title: Metal-based anodes for aluminium production cells
Inventor: DE NORA VITTORIO
IPC: C25C3/12
Filed: 2002-04-10
Abstract: An anode for use in a cell for the electrowinning of aluminium from alumina comprises a substrate with a core having an outer portion made of nickel covered with a barrier layer for inhibiting diffusion of fluoride species oxygen species to the core and preventing diffusion of constituents from the core during use. The barrier layer comprises of 80 to 99 weight% silver and the balance being an electrochemically active noble metal(s) miscible with nickel and silver, e.g. gold or palladium. The anode is coated with an electrochemically active surface layer which can be made of one or more cerium compounds.
Patent NZ-529231-A (NZ)
Title: Once-a-day oxycodone formulations
Inventor: OSHLACK BENJAMIN
IPC: A61K9/52
Filed: 2002-05-02
Abstract: Disclosed is a sustained release osmotic oral dosage form comprising: (a) a bilayer core comprising: (i) a drug layer comprising from about 1 mg to about 640 mg oxycodone or a pharmaceutically acceptable salt thereof; and (ii) a displacement layer comprising an osmopolymer; and (b) a semipermeable wall surrounding the bilayer core having a passageway disposed therein for the release of said oxycodone or pharmaceutically acceptable salt thereof; said dosage form providing an analgesic effect for at least about 24 hours and a mean C24/Cmax oxycodone ratio of 0.6 to 1.0 after once-a-day oral administration at steady state to human patients.
Patent NZ-532076-A (NZ)
Title: Dissolution and processing of cellulose using ionic liquids
Inventor: SWATLOSKI RICHARD PATRICK
IPC: C12N11/12
Filed: 2002-10-03
Abstract: A method for dissolving cellulose is disclosed that comprises: (a) admixing cellulose with a molten ionic liquid in the substantial absence of water or a nitrogen-containing base to form an admixture, wherein the ionic liquid is comprised of cations and anions, wherein said ionic liquid is molten at a temperature of less than about 150 °C; (b) irradiating the admixture with microwave radiation to assist in dissolution; and (c) agitating the admixture until dissolution is complete. Through this method cellulose is dissolved in an ionic liquid without derivatisation, and is regenerated in a range of structural forms without requiring the use of harmful or volatile organic solvents. Cellulose solubility and the solution properties can be controlled by the selection of the ionic liquid constituents, with small cations and halide or pseudo-halide anions favoring solution.
Patent NZ-532841-A (NZ)
Title: Formation of three dimensional burls in a filled acrylic solid surface material
Inventor: BEITELSHEES CARL P
IPC: B05D7/24
Filed: 2002-10-15
Abstract: A method wherein a series of three-dimensional burls are formed in a filled acrylic solid surface material by curing two partially mixed casting compositions with defined parameters of viscosity, density and surface tension is disclosed.
Patent NZ-533941-A (NZ)
Title: Preparation of stable carbon nanotube dispersions in liquids
Inventor: LOCKWOOD FRANCES E
IPC: D01F9/127
Filed: 2002-12-06
Abstract: Disclosed is a method of preparing a stable dispersion of carbon nano particles in a liquid, comprising the steps of: (a) dissolving a dispersant comprising a surfactant having a low hydrophile-lipophile balance (HLB) value of 8 or less in an amount of from 0.001 to 30 percent, into a major amount of a liquid medium selected from mineral oil, hydrogenated oil, vegetable oil, synthetic oil and combinations thereof, forming a dispersant liquid medium, (b) adding carbon nano material having an aspect ratio of from 500 to 5000, in an amount of from 0.01 to 10.0 percent by weight, into the dispersant liquid medium with mechanical agitation, and (c) forming a uniform suspension of colloidal size solid particles.
Patent NZ-536769-A (NZ)
Title: Lift system
Inventor: ACH ERNST
IPC: B66B7/06
Filed: 2004-11-24
Abstract: Disclosed is a lift system comprising a lift cage, a roller arrangement, a support and/or drive and/or guide element in the form of a belt (30). The roller arrangement comprises two rollers (10, 20) with axes (12 or 22) of rotation which are approximately parallel. The rollers have structured circumferential surfaces (13, 23) with parallel roller ribs and roller grooves and rotate in opposite sense when the lift cage is moved. The belt forms an under-looping for support of the lift cage. It runs directly from the first roller (10) to the second roller (20). The belt has a structured belt main surface (33) which is complementary to the structures of the rollers. In a region disposed between the two rollers the belt is twisted about the longitudinal axis (32) thereof so that the belt main surface comes into engagement with the circumferential surfaces of the two rollers when the belt runs over the rollers rotating in opposite sense.