baber/WOPTO huggingface dataset:
Patent CA-2353115-A1 (CA)
Inventor: IBA KOH
IPC: C12N9/90
Filed: 2001-07-27
Abstract: A novel gene induced by salt stress, barley HVD1 gene, was provided according to this invention and sequence of the gene was determined. Said gene of this invention revealed to encode RNA helicase. Furthermore, it is expected that resistance to salt stress would be rendered to a plant by incorporating said gene, through stabilizing conformation of RNA.
Patent CA-2355738-A1 (CA)
Inventor: LIN YANG-I
IPC: C07D499/04
Filed: 2000-01-26
Abstract: L'invention concerne des composés représentés par les formules (I) et (II), dans lesquelles n vaut 0 ou 1, et si n=1, R est un noyau hétérocyclique à 5 ou 6 chaînons, hydroxy, halogène, oxo, carbamoyle, alcoxy, ou amino disubstitué ; si n=0, R est ester, cyano ou un groupe amide; X est CH ou NH; R¿3? est cyano, méthoxy, ou acétamido; R¿1? est hydrogène, alkyle, une charge négative, un cation sélectionné dans le groupe constitué par du sodium, du potassium, un tétraalkylammonium et un acyloxyalkyle, ou un alcoxycarbonyloxyalkyle; and R¿2? est hydrogène, acyle, un carbamoyle de silyle trisubstitué ou un résidu d'acide aminé; ou des sels pharmaceutiquement acceptables de ces composés.
Patent CA-2355763-A1 (CA)
Inventor: GREINKE RONALD ALFRED
IPC: C01B31/04
Filed: 2001-08-17
Abstract: Intercalated graphite flake is prepared having enhanced exfoliation characteristics in terms of at least one of reduced exfoliation temperature and increased expanded volume (also referred to as "worm volume"). The method entails contacting graphite flake with an organic expansion aid either before immersing in an aqueous intercalant solution or by dissolving the expansion aid in the aqueous intercalant solution prior to subjecting graphite flake to an electrolytic oxidation treatment therein. The graphite flake is subjected to electrolytic oxidation to provide intercalated graphite flake. Then, the intercalated graphite flake is recovered from the bulk of the intercalant solution and is preferably washed and further treated with a suitable surfactant in order to reduce the exposed gallery acids on the subsequently dried flake.
Patent CA-2356053-A1 (CA)
Title: Use of substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives as matrix metalloprotease inhibitors for the treatment of respiratory diseases
Inventor: HENNING ROLF
IPC: A61K31/425
Filed: 1999-12-20
Abstract: Novel 4-Biarylbutyric and 5-Biarylpentanoic Acid Derivatives, use of substituted 4-Biarylbutyric and 5-Biarylpentanoic Acid Derivatives as Matrix  Metalloprotease Inhibitors for the Treatment of Respiratory Diseases, pharmaceutical compositions containing them, and a process for using them. T he compounds of the invention have the generalized formula (I) (T)xA-B-D-E-CO2H  wherein A is an aryl or heteroaryl rings; B is an aryl or heteroaryl ring or  a bond; each T is a substituent group, x is 0, 1, or 2; the group D represents  (a), (b), (c), or (d); the group E represents a two or three carbon chain bearing one to three substituent groups which are independent or are involve d in ring formation, possible structures being shown in the text and claims; a nd each of the substituents on E is an independent substituent; and include pharmaceutically acceptable salts thereof.
Patent CA-2356344-A1 (CA)
Inventor: GSTACH HUBERT
IPC: G01N33/53
Filed: 1999-12-20
Abstract: La présente invention concerne de nouveaux colorants fluorescents de formule (I) qui peuvent être utilisés pour le criblage à haut rendement, aussi bien sur la phase solide que dans une solution homogène. Ces nouveaux colorants fluorescents regroupés sous le terme générique de chimie AIDA sont adaptés à divers procédés de chimie organique effectués sur la phase solide et la phase solution pour synthétiser des molécules devant être étudiées quant à leur utilisation thérapeutique dans divers états pathologiques. Les molécules présentant un intérêt thérapeutique peuvent être synthétisées sous forme de conjugués fluorescents au moyen de deux procédés : dans le premier procédé (a) un support solide est chargé avec un lieur clivable (lieur acide, base, oxydoréducteur ou sensible à la lumière) auquel est ensuite attaché le colorant fluorescent. Les colorants possèdent une deuxième fonctionnalité qui sert de point de fixation aux éléments séparateurs. Le séparateur porte un autre groupe fonctionnel qui sert de point de départ à la synthèse des molécules à étudier ; dans le deuxième procédé (b) le colorant fluorescent peut également être introduit en tant que chapeau terminal dans la dernière étape de synthèse d'une séquence de réaction. Les colorants décrits dans cette invention sont chimiquement stables sur une plage étendue de conditions de réaction habituellement appliquée en chimie organique en phase solide et en phase solution. Les conjugués émettent de la fluorescence dans la plage du spectre de la lumière visible et ultraviolette lorsqu'ils sont excités à des longueurs d'ondes correspondant à leur absorption. Ces propriétés de fluorescence permettent de les utiliser dans de nombreuses applications relatives à des procédés fondés sur la fluorescence destinés à identifier des inhibiteurs d'interactions moléculaires et à identifier des molécules qui se lient à des macromolécules cibles telles que des peptides, des protéines, des acides nucléiques, des glucides et autres. Les technologies de détection par fluorescence utilisées pour surveiller la liaison de conjugués-AIDA à des macromolécules comprennent des techniques macroscopiques classiques (moyennage de l'ensemble) qui détectent des variations de l'intensité de la fluorescence, de l'anisotropie (polarisation), du transfert d'énergie par résonance de fluorescence, de la durée de vie de la fluorescence, du temps de corrélation par rotation ainsi que des techniques spectroscopiques à molécule unique à une et deux dimensions. Les utilisations du colorant englobent la chimie organique de phase solide et de la phase solution, le marquage de composés de faible poids moléculaire, le marquage peptidique, le marquage protéique, la spectroscopie optique et la fluorescence. Des procédés de synthèse de colorants fonctionnalisés et de conjugués de colorants (sur support solide et en solution) sont décrits.
Patent CA-2356548-A1 (CA)
Inventor: YOUNG PAUL E
IPC: A61P25/28
Filed: 1999-12-20
Abstract: The present invention relates to novel Brainiac-5 polypeptides which are members of the Brainiac family. In particular, isolated nucleic acid molecul es are provided encoding the human Brainiac-5 polypeptides. Brainiac-5 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of Brainiac-5 activities. Also provided are diagnostic methods for detecting immune and nervous system - related disorders and therapeutic methods for treating, preventing, and/or diagnosing immune and nervous system-related disorders.
Patent CA-2359175-A1 (CA)
Inventor: SAVOY HAROLDE M
IPC: B42B5/12
Filed: 2001-10-17
Abstract: A covered notebook contained a set of pages linked to the cover of the notebook. The cover of the notebook is of the type having a front cover portion, a back cover portion, and a flexible spine linking the front and back cover portions together. The notebook has two spaced apart bindings extending around the spine on upper and lower portions thereof, for linking together the cover and the set of pages.  The two spaced apart bindings form a mid portion on the spine that is free from the bindings.
Patent CA-2359562-A1 (CA)
Title: Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents
Inventor: BULLOCK WILLIAM H
IPC: A61P25/28
Filed: 1999-12-14
Abstract: This invention relates to 2-arylimino heterocycles, including 2-arylimino-1,  3- thiazolidines, 2-arylimino-2, 3, 4, 5-tetrahydro-1, 3-thiazines, 2-arylimino - 1, 3-thiazolidin-4-ones, 2-arylimino-1, 3-thiazolidin-5-ones, and 2-arylimin o- 1, 3-oxazolidines, and their use in modulating progesterone receptor mediate d processes, and pharmaceutical compositions for use in such therapies.</SDOAB >
Patent CA-2360216-A1 (CA)
Inventor: JAKUBOVIC DAVID ANDREW
IPC: A61K8/00
Filed: 2000-02-10
Abstract: La présente invention concerne des compositions cosmétiques topiques essentiellement constituées de substances lipophiles pour la phase continue, et qui contiennent des composés de vitamine B¿3?. Ces compositions sont utilisées pour améliorer la stabilité et la pénétration dans la peau de compositions contenant des composés de vitamine B¿3?.
Patent CA-2362048-A1 (CA)
Title: Trailer impact suppression apparatus
Inventor: PETERS WELDON J
IPC: B60D1/14
Filed: 2001-11-08
Abstract: A hitch mounting assembly for connecting a vehicle to an object. The hitch includes a first member mountable to the vehicle and a second member for receiving the object that is displaced from the fixed member by a plurality of elongate relevant members.
Patent CA-2363217-A1 (CA)
Inventor: CAMPBELL IAN C
IPC: F24F11/00
Filed: 2001-11-22
Abstract: An environmental monitoring and control system for regulating the environmental conditions of an indoor environment. The system comprises a local area network of Universal Detector-Controllers (UDCs), each UDC device comprising a plurality of environmental monitoring sensors for measuring indoor air composition and characteristics, and a microprocessor for acquiring the sensor measurement data, for recording the measurement data on a datalogger, and for controlling actuators (such as a gas shut-off valve) if required. Over a telecommunications network, a remote computer systems both monitors sensor measurement data and provides to each of the UDCs in the series, a set of customized operating in thereby optimizing the energy usage through a building.
Patent CA-2364473-A1 (CA)
Title: System method and program product for sharing information
Inventor: BURICH JOSEPH A
IPC: G06Q10/10
Filed: 2001-12-04
Abstract: A member accessible information system for managing member information, and selectively providing member information to individual members. The members, typically belong to a common industry, such as the food industry and connect through remotely connected networked computers, such as over the Internet. Members may be food industry members include suppliers, manufacturers and customers, each accessing information supplied by members and maintained by the system. Members may search through previously authorized member provided information. The system includes a central storage which may be located on a database server and which stores product information, e.g., food product information and specifications. Members access the system through a web server. A security policy server verifies what product information and which specifications are to be available to each member. Specifications may be stored centrally or, distributed to member locations. An app server stores and selectively executes applications used by members. User security profiles are stored on and managed by a policy server. Each member's security profile indicate the level of authorization of the corresponding member. A personalization server may be included to record user member characteristics, i.e., content viewed by the member, and personalizes content to subsequently automatically make similar content available to the member. An ad server may be included to schedule, serve and track advertising content provided to members. Orders may be generated and placed automatically. Member use may be tracked to generate member bills automatically and bill individual members.
Patent CA-2367410-A1 (CA)
Title: Novel process for the preparation of 1-phenyl-2-(2-piridyl)ethanamine
Inventor: GILES MELVYN
IPC: A61P43/00
Filed: 2000-04-14
Abstract: A process for the preparation of a compound of formula (I) or a pharmaceutically acceptable salt thereof:     (see formula I) which comprises reaction of a compound of formula (II):    (see formula II) with a compound of formula (III):    (see formula III) in the presence of a metal hexamethyldisilazide and optionally thereafter resolving the enantiomers of compound (I) and forming a pharmaceutically acceptable salt.
Patent CA-2371093-A1 (CA)
Inventor: ZEPPETELLO RENEE A
IPC: G16B45/00
Filed: 2000-04-26
Abstract: A computer system comprising a first database containing records correspondi ng to a plurality of chemical compounds and records corresponding to biological  information related to effects of the plurality of chemical compounds on biological systems and a second database containing records corresponding to  a plurality of molecular targets. The computer system further comprises a thir d database containing records corresponding to tests of ineraction between compounds in the first database and molecular targets in the second database , the tests including information on the effect that a compound from the plurality of compounds has on the interaction of a compound known to interac t with a molecular target from the plurality of molecular targets and said molecular target. Means for setting an interaction test threshold corresponding to said effect and means for selecting the compound when its u se results in a test meeting the interaction test threshold are also included i n the computer system. A user interface is provided to allow a user to view th e selected compound and to selectively view information from the first databas e, the second database, the third database as it relates to a compound record i n the first database or as it relates to a molecular target in the second database.
Patent CA-2372025-A1 (CA)
Title: Method for producing a water-insoluble amorphous or partially amorphous controlled release matrix
Inventor: REIN HUBERT
IPC: A61K9/26
Filed: 2000-04-20
Abstract: The invention relates to a method for producing pharmaceutical forms or preliminary stages thereof by means of extrusion. The pharmaceutical form has a matrix in which the active agent is contained essentially, and whose essential characteristics are determined by the extrusion process and which comprises a polysaccharide and/or a derivative thereof and/or a complex thereof and/or any mixture of the aforementioned substances with other substances and/or saccharides and/or derivatives thereof as an essential constituent, and at least one pharmaceutically active substance. The invention also relates to a pharmaceutical form which has a matrix in which the active agent is contained essentially, and whose essential characteristics are determined by the extrusion process, and which comprises a polysaccharide and/or a derivative thereof and/or a complex thereof and/or any mixture of the aforementioned substances with other substances and/or saccharides and/or derivatives thereof as an essential constituent, and at least one pharmaceutically active substance. Finally, the invention also relates to the use of said pharmaceutical form for producing granulates for tabletting and filling capsules, for further processing using injection moulding techniques and as an auxiliary material for direct tabletting and/or for producing monobloc pharmaceutical forms.
Patent CA-2372256-A1 (CA)
Title: Improved brush-seal designs for turbines and similar rotary apparatus
Inventor: DALTON PATRICK S
IPC: F16J15/32
Filed: 2001-04-05
Abstract: An axial flow turbine is provided with retractable packing and brush seals between stages. The retractable packing is provided with separate packing segments which form a ring when closed during normal operation and expand to a larger clearance during start-up and shut-down. A brush seal segment is provided on each packing segment, such that when segments are closed during normal operation, the brush seal likewise forms a ring. The ends of the packing segments are cut along radii extending from the central shaft, and the ends of the brush seal segments are canted so as not to be parallel with the ends of the packing segments in which they lie.
Patent CA-2372721-A1 (CA)
Inventor: HJERTMAN BIRGER
IPC: A61M5/24
Filed: 2000-05-11
Abstract: L'invention concerne un dispositif d'injection et son mode de fonctionnement destinés à des conteneurs dotés d'une ouverture destinée à une aiguille d'injection, par exemple, une seringue. L'injecteur comprend un boîtier, un siège ou un support conçu pour maintenir l'aiguille ou le conteneur et pour permettre son déplacement axial par rapport au boîtier entre une position arrière, couvrant l'aiguille, et une position avant, découvrant l'aiguille. Il comprend également un système de pénétration permettant d'amener l'aiguille de la position arrière à la position avant, un système de retour permettant au moins d'amener l'aiguille vers l'arrière et un système d'injection permettant au moins d'expulser le contenu du conteneur par l'aiguille. Il comprend également un bouton de commande qui est situé sur le boîtier et qui permet, par un système de transmission et de commutation de déclencher graduellement le système de pénétration et d'injection. Le bouton est conçu de façon à avoir au moins un composant mobile perpendiculairement à l'axe de l'aiguille.
Patent CA-2372737-A1 (CA)
Inventor: NOMOTO HIROKI
IPC: G01F13/00
Filed: 1999-04-30
Abstract: A powder and granular material feeding device (1) for feeding powder and granular material supplied from a power and granular material feeding part ( 2) through a feeding part (3), wherein powder and granular material is fed into  a transport means (8) from an inlet port (6) provided in a pressure resistant case (5) of the feeding part (3), transported by the transport means (8), an d discharged from an outlet port (7) so as to supply it to a part to be fed with, whereby the powder and granular material feeding part (2) and the pressure resistant case (5) of the feeding part (3) can be provided fixedly,  the powder and granular material feeding device (1) can be formed as a close d system without providing any special joint such as an expansion joint in a connection part between the pressure resistant case (5) and the powder and granular material feeding part (2) and a connection part between the pressur e resistant case (5) and the part (2) to be fed with and, because only the transport means (8) is installed in the pressure resistant case (5), the structure of the powder and granular material feeding device (1) is simplifi ed and downsized remarkably, the overall height of the device is kept unchanged , and the installation space and equipment cost are reduced.
Patent CA-2373897-A1 (CA)
Inventor: HAGIWARA ATSUSHI
IPC: H01M8/02
Filed: 2002-02-28
Abstract: A fuel cell separator composition containing an electrically conductive carbonaceous powder and a binder that is a mixture of a thermoset resin with a polyoxazine compound having a plurality of oxazine rings can be used to efficiently mass-produce high-modulus fuel cell separators of excellent dimensional stability and gas impermeability.      By employing such fuel cell separators as some or all of the separators in a solid polymer fuel cell, there can be obtained solid polymer fuel cells which are not subject to cracking or breakage during assembly, have good gas sealing properties, and ate endowed with excellent vibration and impact resistance.
Patent CA-2375642-A1 (CA)
Inventor: GERDEMAN ROGER J
IPC: B42F7/00
Filed: 2000-06-05
Abstract: A storage device (10, 200) for retaining one or more sheet items (12) for access by a user. The storage device (10) has a storage device cover (16) including front and rear panels (18, 20), and contains one or more first binding members (32) which receive apertures (14) formed in the sheet items (12) to register the sheet items relative to the cover (16). One or more second binding members (38) are hingedly connected to the storage device cover (16) and preferably operate independently of the front and rear panels (18, 20) of the cover (16) to engage the first binding members (32).  Retained sheet items (12) are able to be moved from a first position generally parallel with the rear panel (20) to a second position generally parallel with the front panel (18). Alternatively, the storage device (100, 300) includes a single panel (20) that carriers the first and second binding members (32, 38).
Patent CA-2375956-A1 (CA)
Title: Abrasive tools for grinding electronic components
Inventor: MATSUMOTO DEAN SABURO
IPC: H01L21/304
Filed: 2000-04-28
Abstract: Abrasive tools containing high concentrations of hollow filer materials in a resin bond are suitable for polishing and backgrinding of hard materials, such as ceramic wafers and components requiring a controlled amount of surface defects. These highly porous abrasive tools comprise fine grit abrasive grain, such as diamond abrasive, along with the hollow filler material and resin bond, comprising a backing and an abrasive rim containing a maximum of about 2 to 15 volume percent abrasive grain, the abrasive grain having a maximum grit size of 60 microns, wherein the abrasive rim comprises resin bond and at least 40 volume percent hollow filler materials, and the abrasive grain and resin bond are present in the abrasive rim in a ratio of 1.5:1.0 to 0.3:1.0 grain to bond.
Patent CA-2376506-A1 (CA)
Inventor: MORGAN BARRY A
IPC: A61P25/28
Filed: 2000-06-05
Abstract: A novel class of analogs which exhibit both high affinity and selectivity for Neuromedin B and Somatostatin receptors are claimed. One example is Nal-Tyr-cyclo(D-Cys-D-Trp-Lys-D-Cys)-Abu-Nal-NH2.
Patent CA-2376839-A1 (CA)
Title: Flapper valve with dual action arm
Inventor: ANDERSEN TERRENCE J
IPC: E03D1/34
Filed: 2002-03-15
Abstract: A flapper valve assembly for regulating the passage of water from a toilet tank is provided with a structure to reduce overflow risk. There is a yoke pivotally disposed in the tank and supporting a flapper seal that can be seated on and unseated from the flush opening. A flapper arm has a first segment coupled to the yoke along a pivot axis and a second segment extending away from the pivot axis toward the flapper seal. The flapper arm is configured such that it delays seating of the flapper seal when the water in the tank is above a predetermined level and assists seating of the flapper seal when the water is below a designated level.
Patent CA-2379113-A1 (CA)
Inventor: BARRAULT MICHEL
IPC: H02J7/00
Filed: 2000-06-21
Abstract: In a method of charging several electrochemical cells 5, 6, 7 connected in series, by a charger 1 which allows adjusting the voltage and the charging current, the voltage of each cell is detected permanently, and when a first cell reaches a predetermined threshold voltage, an increment of the charging current is applied to several cells 5, 6, 7 and simultaneously a shunt resistor of a current equivalent to the increment in the charging current of the several said cells 5, 6, 7 is connected in parallel to said first cell, and when each of the subsequent cells reaches the threshold voltage, a shunt resistor of a current equal to the increment in charging current of said several cells 5, 6, 7 is also connected in parallel to this cell. The invention is applicable to the use of accumulator systems for powering electric vehicles and thermal vehicles with self-contained electric mode.