baber/WOPTO huggingface dataset:
Patent MY-190705-A (MY)
Title: A system and method for integration of biometric recognition of variable computing cost and complexities
Inventor: ALWYN GOH
IPC: G06K9/00
Filed: 2016-06-30
Abstract: The present invention provides a framework for integration of biometric recognition methodologies of variable computation cost. The system of the present invention comprises a Detection Module (102) which captures images through a camera from a user and detects biometric data through a browser at the client platform; an Image Processing Module (104a and 104b) which enhances the quality of ROI images through relatively fast and relatively slow processing which will enhance the quality of biometric image; a Feature Extraction Module (106a and 106b) which extracts facial features by means of multiple methods which range from relatively computation-inexpensive to relatively computation- expensive from enhanced ROI images; a Feature Matching Module (108a and 108b) which calculated distances between the multiple feature vectors previously extracted and the multiple feature vector which has been stored in database; and an Authentication Module (110) which combines multiple distance scores obtained from Feature Matching process in order to undertakes decision of acceptance or rejection of user based on submission of applicable video-stream. In the present invention, biometric data is captured by means of an apparatus (i.e. camera) attached to the client platform. Upon capturing biometric data by utilizing camera, the processes of biometric detection, signal processing and feature extraction are executed. Concurrent execution of expensive and inexpensive computation would respectively result in relatively slow and relatively fast computation of the biometric feature vectors associated with the user of interest. The present invention allows integration of these relatively fast and slow assessments of biometric authenticity, and also for multiple progressive assessments based on the relative speed of these computations. (The most illustrative drawing is FIG. 1.0.)
Patent MY-174305-A (MY)
Title: Process and apparatus for manufacture of hydroxide slurry
Inventor: SCEATS MARK
Filed: 2014-10-15
Abstract: A method of manufacture of high solids hydroxide slurries from caustic calcined carbonate powder is described, whereby the properties of the slurry are its low resistance to shear thinning to facilitate transport, and a high stability for transport and storage, and ease of reconstitution after long periods of storage, and, as required, a high concentration of chemically reactive species at the particle surface. The method achieves these specifications by mixing caustic calcined carbonate or hydroxide powder with water in an insulated reactor vessel (100), and agitating the slurry sufficiently such that the hydration reaction causes the water to spontaneously boil, such that the remaining hydration proceeds spontaneously under the fixed conditions of boiling through the water loss. The mixing process is preferably carried out by a shear pump (105). A viscosity modifier, such as acetic acid, is used to thin the slurry to enable the mixing system to maintain uniform mixing. The reaction is terminated when the boiling has spontaneously ceased and the temperature has spontaneously dropped to a set point though the reactor heat losses, where the processing time is sufficiently long that the slurry meets the desired specifications.      Figure 1
Patent MY-182653-A (MY)
Title: Self-aligned gate edge and local interconnect and method to fabricate same
Inventor: WEBB MILTON CLAIR
Filed: 2013-12-19
Abstract: Self-aligned gate edge and local interconnect structures and methods of fabricating self-aligned gate edge and local interconnect structures are described. In an example, a semiconductor structure (800) includes a semiconductor fin (804, 805) disposed above a substrate (802) and having a length in a first direction. A gate structure (808) is disposed over the semiconductor fin (804, 805), the gate structure (808) having a first end opposite a second end in a second direction, orthogonal to the first direction. A pair of gate edge isolation structures (820) is centered with the semiconductor fin (804, 805). A first of the pair of gate edge isolation structures (820) is disposed directly adjacent to the first end of the gate structure (808), and a second of the pair of gate edge isolation structures (820) is disposed directly adjacent to the second end of the gate structure (808).
Patent MY-192764-A (MY)
Title: Laser processing method, apparatus for sapphire and storage medium
Inventor: WANG YANHUA
IPC: B23K26/38
Filed: 2016-04-29
Abstract: A laser processing method for a sapphire (18) includes: acquiring an image of the sapphire (18) during processing; performing an edge detection to the image to acquire a coordinate of a crack (5, 50); determining an offset parameter according to the coordinate of the crack (5, 50); adjusting a laser processing position according to the offset parameter; and further processing the sapphire (18) in accordance with the adjusted laser processing position.
Patent MY-187292-A (MY)
Title: Frame structure and method of constructing frame structure
Inventor: KAZUHITO SUGAYA
Filed: 2015-12-04
Abstract: Provided is a frame structure which allow PC members to be assembled in an efficient manner. First blind holes 26 are formed in a first PC beam 11 so as to open out at longitudinal end surfaces thereof, and first through holes 31 are formed in a pair of PC columns 10 so as to open out opposite to the respective first blind holes 26. The first PC beam 11 is rigidly connected to each PC column 10 via a first rebar 32 positioned in each first through hole 31 and inserted in the corresponding first blind hole 26 to be connected to the corresponding first main beam rebar 24 via a first overlap joint 33, and grout filled around the first rebar 32 in the first through hole 31. (Figure 8)
Patent MY-188242-A (MY)
Title: Intranasal administration
Inventor: DJUPESLAND PER GISLE
IPC: A61M15/00
Filed: 2015-11-19
Abstract: A nosepiece (117) for delivering substance to a nasal cavity of a subject, the nosepiece comprising a body part (202) which comprises a base portion (208) which defines a flow passage (209) therethrough, and a projection (212) at a distal end of the base portion which at least in part provides a tip of the nosepiece and confers a rigidity in the sagittal direction, which enables the tip to open fleshy tissue at an upper region of the nasal valve and thereby expand an open area of the nasal valve, and a flexibility in a lateral direction, orthogonal to the sagittal plane, which facilitates insertion of the tip into the nasal valve.
Patent MY-192620-A (MY)
Title: Method for gradual sealing of a gas
Inventor: HOFEL TORBEN
IPC: F04D29/58
Filed: 2017-02-20
Abstract: A method is proposed for compressing a gas in stages in a compressor arrangement (100, 200, 300, 400) having a plurality of compression stages (I-VI) which are connected together sequentially by a main line (1) and in which the gas, guided through the main line (1), is respectively compressed from a suction-side pressure level to a pressure-side pressure level and is heated by this compression from a suction-side temperature level to a pressure-side temperature level, wherein a feedback amount of the gas, guided through the main line (1), is at least temporarily removed from the main line (1) downstream of one of the compression stages (V), is fed to an expansion process, and is fed back into the main line (1) upstream of the same compression stage (V). It is provided that the pressure-side pressure level of the compression stage (V) downstream of which the feedback amount is removed from the main line (1) is a supercritical pressure level, that the feedback amount is expanded to a subcritical pressure level, that the feedback amount is fed to the expansion process at the pressure-side temperature level of the compression stage (V) downstream of which it is removed from the main line (1), and that the feedback amount is cooled only after being expanded and before and/or after being fed back into the main line (1). The invention also relates to a compressor arrangement (100, 200, 300, 400).  [Fig. 3]
Patent MY-183778-A (MY)
Title: Method for manufacturing wet rubber masterbatch, method for manufacturing rubber composition, and method for manufacturing tire
Inventor: NISHIMURA CHIYA
Filed: 2016-05-10
Abstract: A problem which is addressed is the provision of a method for manufacturing a wet rubber masterbatch that will serve as raw material for vulcanized rubber which excels in fatigue resistance, ability to achieve reduced heat generation, and tensile characteristics. A wet rubber masterbatch may be manufactured by means of a method comprising an operation in which a latex that has magnesium present therein in an amount which is not greater than 150 ppm is prepared; and an operation in which a liquid mixture that comprises a rubber component and carbon black is made. The latex may comprise rubber particles for which the 90 vol% particle diameter is not greater than 2 ?m. The operation in which the liquid mixture is made may comprise a step (a) in which the latex and a dispersion solvent are mixed; and a step (b) in which a latex solution obtained at the foregoing step (a) and a slurry containing the carbon black are mixed. The method for manufacturing a wet rubber masterbatch may satisfy Formula 1, below.  0.1< b/a < 1.0 (Formula I)  (At Formula 1, a indicates amount (ppm) of magnesium present in latex; b indicates amount (parts by mass) of carbon black in the liquid mixture for every 100 parts by mass of rubber component in the liquid mixture.)
Patent MY-196315-A (MY)
Title: Screen Plate and Method for Manufacturing Same
Inventor: KURAHASHI SHINJI
IPC: B41F15/36
Filed: 2017-12-06
Abstract: To provide a screen plate that can allow printing accuracy to be improved. A screen plate (1) comprising a plate frame (2) and a screen gauze (3) formed of warp and weft fibers (3a, 3b) each made of a synthetic fiber, wherein the screen gauze (3) is stretched on the plate frame (2) under application of a predetermined tensile force, and the thickness of the screen gauze (3) stretched on the plate frame (2) is 88% or less based on the thickness of the screen gauze (3) under application of no tensile force.  FIG. 1
Patent MY-195618-A (MY)
Title: Use of a Long Acting Glp-1/Glucagon Receptor Dual Agonist for the Treatment of Non-Alcoholic Fatty Liver Disease
Inventor: HWANG SANG YOUN
IPC: C07K16/00
Filed: 2015-09-16
Abstract: The present invention relates to a pharmaceutical composition for the prevention or treatment of non-alcoholic fatty liver disease including a long-acting GLP-1/glucagon receptor dual agonist, and a method for preventing or treatment of non-alcoholic fatty liver disease including administering the composition. The composition of the present invention either has no side effect of weight gain or reduces the side effect of weight gain, which is a side-effect of conventional therapeutic agents for non-alcoholic fatty liver disease, and reduces the amount of administrations of a long-acting GLP- 1/glucagon receptor dual agonist, thus greatly improving patient's convenience. In addition, the long-acting GLP-1/glucagon receptor dual agonist of the present invention improves in vivo sustainability and stability.
Patent MY-194720-A (MY)
Title: Surface treated copper foil and copper clad laminate
Inventor: ORI YUKI
IPC: H05K1/03
Filed: 2019-03-12
Abstract: A surface treated copper foil includes a surface treatment layer made of the silane compound on a surface of a copper foil. In the surface treated copper foil, a measurement of the surface treatment layer made of the silane compound by TOF-SIMS shows a peak detected at a position of at least one mass number (m/z) selected from the group consisting of from 240.9 to 241.1, from 241.9 to 242.1, from 242.9 to 243.1, from 243.9 to 244.1, from 244.9 to 245.1, from 260.9 to 261.1, from 261.9 to 262.1, and from 262.9 to 263.1.
Patent MY-173190-A (MY)
Title: Interactive electronic continued professional development (ie-cpd) system
Inventor: DR RAFIZA BINTI ABDUL RAZAK
IPC: G09B19/00
Filed: 2014-09-09
Abstract: The present invention disclosed an interactive electronic continued professional development (ie-CPD) system (10) which is an online training system for teachers to enhance their competency, professionalisms, skills and knowledge that comprising an authentication unit (11), a teacher system unit (12), a notification system (13), a Ministry of Education system unit (14), a database unit (15), an administration unit (16), a retrieve unit (17). The teacher system unit (12) is further configured with a training unit (18), an activity unit (19), and a communication unit (20). The training unit (18) is configured to interacting with: an analysis unit (21) that configured to provide an analysis on courses and tests taken and evaluate credit hour of the courses taken and the test results of the courses taken; and a reward unit (22) configured to provide a certificate for completed courses and tests which further comprises of institutional reward (48) and personal reward (49).
Patent SG-10201809818X-A (SG)
Title: Ciht power system
Inventor: MILLS RANDELL L
Filed: 2013-05-21
Abstract: CIHT POWER SYSTEM An electrochemical power system is provided that generates an electromotive force (EMF) from the catalytic reaction of hydrogen to lower energy (hydrino) states providing direct conversion of the energy released from the hydrino reaction into electricity, the system comprising at least two components chosen from: H2O catalyst or a source of H2O catalyst; atomic hydrogen or a source of atomic hydrogen; reactants to form the H2O catalyst or source of H2O catalyst and atomic hydrogen or source of atomic hydrogen; and one or more reactants to initiate the catalysis of atomic hydrogen. The electrochemical power system for forming hydrinos and electricity can further comprise a cathode compartment comprising a cathode, an anode compartment comprising an anode, optionally a salt bridge, reactants that constitute hydrino reactants during cell operation with separate electron flow and ion mass transport, a source of oxygen, and a source of hydrogen. Due to oxidation-reduction cell half reactions, the hydrino-producing reaction mixture is constituted with the migration of electrons through an external circuit and ion mass transport through a separate path such as the electrolyte to complete an electrical circuit. A power source and hydride reactor is further provided that powers a power system comprising (i) a reaction cell for the catalysis of atomic hydrogen to form hydrinos, (ii) a chemical fuel mixture comprising at least two components chosen from: a source of H2O catalyst or H2O catalyst; a source of atomic hydrogen or atomic hydrogen; reactants to form the source of H2O catalyst or H2O catalyst and a source of atomic hydrogen or atomic hydrogen; one or more reactants to initiate the catalysis of atomic hydrogen; and a support to enable the catalysis, (iii) thermal systems for reversing an exchange reaction to thermally regenerate the fuel from the reaction products, (iv) a heat sink that accepts the heat from the power-producing reactions, and (v) a power conversion system. [Fig. 1]
Patent SG-11201807950T-A (SG)
Title: Multi-unit plate for immunoblot analysis
Inventor: ZHANG JIANDI
IPC: G01N33/543
Filed: 2016-01-20
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization MD 1111101110101011111 OH 1101011101111111111111011100101 1111110111011# International Bureau 0.. .... .. (10) International Publication Number ..... ...,/ (43) International Publication Date WO 2016/188132 Al 1 December 2016 (01.12.2016) WI P0 I P CT (51) International Patent Classification: AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, G01N 33/543 (2006.01) BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (21) International Application Number: HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, PCT/CN2016/071433 KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, (22) International Filing Date: MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, 20 January 2016 (20.01.2016) PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, (25) Filing Language: English TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (26) Publication Language: English (84) Designated States (unless otherwise indicated, for every (30) Priority Data: kind of regional protection available): ARIPO (BW, GH, 14/721,205 26 May 2015 (26.05.2015) US GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, (71) Applicant: YANTAI ZESTERN BIOTECHNIQUE TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, CO., LTD [CN/CN]; Bioasis, #39, Keji Ave., Yantai Hi- DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, tech District, Yantai, Shandong 264670 (CN). LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, (72) Inventor: ZHANG, Mandl; Bioasis, #39, Keji Ave., Yantai Hi-tech District, Yantai, Shandong 264670 (CN). GW, KM, ML, MR, NE, SN, TD, TG). (74) Agent: KEYCOM PARTNERS, P.C.; 1404/1405, Block Published: A, No. 7, Zhichun Road, Haidian District, Beijing 100191 — with international search report (Art. 21(3)) (CN). — with amended claims and statement (Art. 190)) (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, = = (54) Title: MULTI-UNIT PLATE FOR IMMUNOBLOT ANALYSIS 1c. IIIRRIRMIK ,. ,--------i 02 1O3 M 11 GC ot ,—, Fig.1 Il (57) : A multi-unit plate with at least one unit that comprise a membrane, preferably nitrocellulose or PVDF membrane, is N provided. The membrane of the unit is associated with a supporting structure to allow for electroblotting. This multi-unit plate is suited for high throughput immunoblot analysis including Zestern analysis.
Patent SG-11201909059X-A (SG)
Title: Solid form of (s)-[2-chloro-4-fluoro-5-(7-morpholin-4-ylquinazolin-4-yl)phenyl]-(6-methoxy-pyridazin-3-yl)methanol
Inventor: LANGE MICHAEL
IPC: C07D403/10
Filed: 2018-03-28
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 04 October 2018 (04.10.2018) W I PO I PCT o °nolo VIII n mum oimiE (10) International Publication Number WO 2018/178133 Al (51) International Patent Classification: C07D 403/10 (2006.01) A61P 35/00 (2006.01) (21) International Application Number: PCT/EP2018/057875 (22) International Filing Date: 28 March 2018 (28.03.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 17163826.5 30 March 2017 (30.03.2017) EP (71) Applicant: MERCK PATENT GMBH [DE/DE]; Frank- furter Strasse 250, 64293 DARMSTADT (DE). (72) Inventors: LANGE, Michael; Am Blauen Stein 4, 64295 DARMSTADT (DE). KUEHN, Clemens; Im Appensee 19, 64291 DARMSTADT (DE). FUCHSS, Thomas; Jahn- strasse 12, 64625 BENSHEIM-AUERBACH (DE). MAIL- LARD, David; Martinstrasse 81, 64285 DARMSTADT (DE). BREUNING, Marcel; Uhlandstrasse 11, 60314 FRANKFURT AM MAIN (DE). POMA, Marco; Via E. Q. Visconti 60, 00193 ROME (IT). BURINI, Edoardo; Via Puglie 5, 00012 GUIDONIA MONTECELIO (IT). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). It Published: with international search report (Art. 21(3)) 00 N 1-1 (54) Title: SOLID FORM OF (S)-[2-CHLORO-4-FLUORO-5-(7-MORPHOLIN-4-YLQUINAZOLIN-4-YL)PHENYL]-(6- 00 METHOXY-PYRIDAZIN-3-YL)METHANOL 1-1 0 (57) : The present invention relates to anhydrous disordered crystalline (S)42-chloro-4-fluoro-5-(7-morpholin-4-ylquina- \" zolin-4-yl)pheny1]-(6-methoxy-pyridazin-3-yl)methanol, as well as a method of making same, and pharmaceutical compositions and 0 medical uses thereof.
Patent SG-11201909895U-A (SG)
Title: Combination of a 5-ht6 receptor antagonist and an acetylcholinesterase inhibitor for use in the treatment of alzheimer's disease in a patient subpopulation carrying apoe4 alleles
Inventor: WINDFELD KRISTIAN
IPC: A61K45/06
Filed: 2018-05-22
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 29 November 2018 (29.11.2018) WIPO I PCT ~ill IIIIIIIIII1101OlDIIIIIIIHo DVIIIIIIIIIIIIIIIIMDIIIIII ° iflo oimIE (10) International Publication Number WO 2018/215478 Al (51) International Patent Classification: A61K 31/4045 (2006.01) A61K 31/27 (2006.01) A61K 31/445 (2006.01) A61K 31/55 (2006.01) A61K 31/496 (2006.01) A61K 45/06 (2006.01) A61K 31/505 (2006.01) A61P 25/28 (2006.01) (21) International Application Number: PCT/EP2018/063402 (22) International Filing Date: 22 May 2018 (22.05.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: PA201700313 24 May 2017 (24.05.2017) DK PA201700538 29 September 2017 (29.09.2017) DK (71) Applicant: H. LUNDBECK A/S [DK/DK]; Ottiliavej 9, 2500 Valby (DK). (72) Inventor: WINDFELD, Kristian; c/o H. Lundbeck A/S Ottiliavej 9, 2500 Valby (DK). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. = (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) 00 N 11 ! (54) Title: COMBINATION OF A 5-HT6 RECEPTOR ANTAGONIST AND AN ACETYLCHOLINESTERASE INHIBITOR FOR 00 USE IN THE TREATMENT OF ALZHEIMER'S DISEASE IN A PATIENT SUBPOPULATION CARRYING APOE4 ALLELES O 1-1 (57) : The present invention relates to 5-HT6 receptor antagonists for use in the treatment of Alzheimer's disease, wherein the Alzheimer's disease patient carries one or two ApoE4 alleles, comprising administering an effective dose of a 5-HT 6 receptor antagonist C to improve or augment the effect of an acetylcholinesterase inhibitor.