baber/WOPTO huggingface dataset:
Patent IL-80256-A0 (IL)
Title: Automatic injector
IPC: A61M5/31
Filed: 1986-10-08
Abstract: An automatic injector for injecting one or more different injection liquids, comprising a combination of a substantially cylindrical means (21) containing a discharge mechanism (43) and a plurali­ty of cartridge elements. The cartridge elements comprise a pis­ton (24) in the substantially cylindrical means, a sealing stopper (41, a number of separating stoppers (40,72) equal to one less than the number of the liquids, and a needle holder (30) with injection needle (34). The needle holder comprises a stopper that is movable in the substan­tially cylindrical means and comprises a longitudinal bore. The injector comprises a by-pass means for injection liquid in front of the sealing stopper. In another embodiment the injector com­prises a combination of a discharge mechanism, a cartridge holder and a cartridge, the cartridge comprising a barrel including the plurality of cartridge elements, wherein the by-pass for injec­tion liquid comprises at least one duct recessed in the wall of the shaft of the needle holder, the needle holder being connected to the barrel, at least one aperture being recessed in the front of the shaft of the needle holder. In yet another embodiment, the injector is suitable for accommodating a solid and solvent therefor, and for that purpose comprises a solvent by-pass means and a passable stopper between the solid and the solvent, in which the solvent can pass the passable stopper by a telescoping movement of external components of the injector and can reach the solid, as a result of which the injector is made ready for use.
Patent IL-80365-A0 (IL)
Title: Tetrachlororaffinose derivatives and process for the preparation of sucralose utilizing the same
IPC: C12R1/645
Filed: 1986-10-20
Abstract: The novel chlorinated sugar O -a-D-6-chloro-6-deoxyg- alactopyranosyl-(1 → 6)-a-D-4-chloro-4-deoxygalactopyran- osyl-(1 - 2)-β-D-1, 6-dichloro-1, 6-dideoxyfructofuranoside (TCR) can be used to prepare sucralose by incubating the TCR in solution in the presence of an enzyme serving to remove the 6-chloro-6-deoxygalactosyl moiety from the 6-position, especially an enzyme derived from a strain of Mortierella vinacea, Circinella muscae or Aspergillus niger. TCR is prepared by treating raffinose with thionyl chloride in the presence of triphenylphosphine oxide.
Patent IL-90409-A0 (IL)
Title: Macrocyclic chelates
IPC: A61K51/08
Filed: 1989-05-25
Abstract: The invention is a chelate of formula I:   <IMAGE>ember selected from the group consisting of -NO2, -NH2, -NCS, -NHCOCH2-Z, with Z being a member selected from the group consisting of Br and I, -COOH; and -OCH2OOCH; and M is a metal ion selected from the group of elements consisting of Bi, Pb, Y, Cd, Hg, Al, Th, Sr, and Lanthanides. The invention also includes a chelate, wherein M is a copper ion and n is an integer from 2 to 5. The invention includes chelate conjugates of formula I and ligand conjugates of formula II:   <IMAGE>   The invention also includes methods to use these compounds for treatment of cellular disorders and for diagnostic tests.
Patent IL-91381-A0 (IL)
Title: Wedge-shaped port for flexible containers
IPC: A61J1/05
Filed: 1989-08-22
Abstract: A wedge-shaped access port (18) for a flexible container (10) which is formed of at least one or more sheets of material (12) which are sealed together about the edges (14) to form a cavity (16). The wedge-shaped port (18) is sealed to the container (10) so that a base (22) of the wedge is exterior to the cavity (16) and a thin edge of the wedge is located inside the cavity (16). An orifice (20) in the port (18) provides a passageway from the base (22) of the wedge to the cavity (16). The wedge shape of the port (18) allows sealing of the port (18) to container (10) with minimal stress or thinning of material at the seal between the port (18) and the container (10).
Patent IL-92250-A0 (IL)
Title: Diagnostic media and assay for detecting fungicide resistance
IPC: C12Q1/04
Filed: 1989-11-08
Abstract: A diagnostic media and assay, as further described herein, for detecting fungicide resistant strains of fungal plant pathogens.
Patent SE-8204332-A0 (SE)
Title: Cellodling, viruspropagering och interferonproduktion på serumfritt medium
Inventor: BJARE U
IPC: C12N5/00
Filed: 1982-07-14
Abstract: Uppfinningen avser ett fOrfarande for odling av cell-linjer pa serumfritt medium med konventionell sammansdttning betraffande oorganiska salter, aminosyror och vitaminer, vilket kannetecknas av att man anvander ett odlingsmedium som dessutom innehaller tillsats av transferrin samt kasein och/eller albumin.
Patent FI-20011651-A0 (FI)
Inventor: POEYHOENEN PETTERI
IPC: H04L29/06
Filed: 2001-08-15
Abstract: The present invention concerns a method of network layer load balancing for a server farm (group of servers located on the same link) that provide identical, transaction and UDP based services, e.g. DNS service. Load balancing functionality is based on the use of the IPv6 anycast addressing for the service queries and specific Neighbour Advertisement messaging.
Patent FI-20070630-A0 (FI)
Inventor: RANTALAINEN ERKKI
IPC: F21V/
Filed: 2007-08-21
Abstract: An arrangement for distributing radiation, the arrangement comprising a radiation source (1) and a plate-like distributor element (3), positioned in the passage of a radiation beam (2) produced by the radiation source, for distributing the radiation. According to the invention, the radiation beam (2) is oriented at a slight angle to the plane (4) of the distributor element, and the distributor element comprises a plate-like body portion (5) made from a transparent material and reflective surfaces (7) arranged stepwise one after the other and side by side on the body portion (5) in the direction of the radiation beam (2) and at an angle to the plane (4) of the distributor element for dividing the radiation beam into substantially mutually parallel sub-beams (8) in a direction that differs from the direction of the radiation beam.
Patent IL-104083-A0 (IL)
Title: Ecologically harmless raw materials produced from liquid and solid useful as valuable material for building and construction proucts
IPC: C04B26/16
Filed: 1992-12-14
Abstract: The invention relates to an ecologically sound disposable product, for example usable as a building material, obtained from wastes, and to a process for the production thereof. By means of specific additives, the process can be controlled in such a way that the end product has varying building material properties and that pollutants, which have been present in the starting material, are present in the end product either as harmless substances, which have been reacted further, or in a bound or immobilised form.
Patent IL-110523-A0 (IL)
Title: Molded structure comprising a thermoplastic process for its production and its use
IPC: B01J20/26
Filed: 1994-08-01
Abstract: A structure 1 produced by extrusion, such as a plastics foam sheet, a board, a profiled element or the like, contains at least 10 % by volume of open cells 2, 4, which have a polyhedral shape and adjoin one another. By using an increased temperature in extrusion, in comparison with the extrusion of closed-cell thermoplastic structures, the deformation-free opening of the cells is brought about. In that case, webs 3 of cell walls 5, 6 remain unaffected in their shape, whether they have openings 7 or no passages, so that mechanial strength of the cell framework or of the three-dimensional matrix is preserved. <IMAGE>
Patent IL-110879-A0 (IL)
Title: Magnetic rotating apparatus
IPC: H02K53/00
Filed: 1994-09-05
Abstract: On a rotor (6;8) which is fixed to a rotatable rotating shaft (4), a plurality of permanent magnets (22A-22H) are disposed along the direction of rotation such that the same magnetic pole type thereof face outward. In the same way, balancers (20A-20H) are disposed on the rotor for balancing the rotation of this rotor. Each of the permanent magnets is obliquely arranged with respect to the radial direction line of the rotor. At the outer periphery of the rotor, an electromagnet (12;14) is disposed facing this rotor, with this electromagnet intermittently energized based on the rotation of the rotor. According to the magnetic rotating apparatus of the present invention, rotational energy can be efficiently obtained from permanent magnets. This is made possible by minimizing as much as possible current supplied to the electromagnets, so that only a required amount of electrical energy is supplied to the electromagnets. <IMAGE>
Patent IL-128623-A0 (IL)
Title: Gift token
IPC: G07F1/06
Filed: 1997-08-15
Abstract: A gift token has a card-like handy body member with an appropriate imprint and representing a certain exchange-value which is exchangeable for a chosen good. The body member includes an integrated circuit with an electronically readable and programmable memory, intended for the storage (at least temporarily) of the above-mentioned exchange value, in a way which is compatible with an existing electronic payment system.
Patent IL-129136-A0 (IL)
Title: Compositions and method for removing paint from a substrate
IPC: C09D9/00
Filed: 1997-10-22
Abstract: A paint stripper for use by immersion of a painted substrate in a bath of the composition or application in place has two phases, one aqueous and the other of partially water soluble organic solvent. The aqueous phase is saturated with organic solvent. The organic solvent is preferably benzyl alcohol, dibasic ester or ethyl-e-ethoxypropionate, The total amount of organic solvent in the bath is suitably in the range 2 to 20%. The stripper may be acid or alkali activated. The application stripper is thickened to avoid separation during storage.
Patent IL-142056-A0 (IL)
Title: Process for obtaining hmg-coa reductase inhibitors of high purity
IPC: A61K31/40
Filed: 1999-09-17
Abstract: Lovastatin, pravastatin, simvastatin, mevastatin, atorvastatin, and derivatives and analogs thereof are known as HMG-CoA reductase inhibitors and are used as and antihypercholesterolemic agents. The majority of them are produced by fermentation using microorganisms of different species identified as species belonging to Aspergilus, Monascus, Nocardia, Amycolatopsis, Mucor or Penicilium genus, some are obtained by treating the fermentation products using the method of chemical synthesis or they are the products of total chemical synthesis. The purity of the active ingredient is an important factor for manufacturing the safe and effective pharmaceutical, especially if the pharmaceutical product must be taken on a longer term basis in the treatment or prevention of high plasma cholesterol. The accumulation of the impurities from the pharmaceuticals of lower purity may cause many side effects during the medical treatment. The present invention relates to a new industrial process for the isolation of HMG-CoA reductase inhibitors using so-called displacement chromatography. Use of the invention enables to obtain HMG-CoA reductase inhibitors of high purity, with high yields, lower production costs and suitable ecological balance.
Patent IL-145111-A0 (IL)
Title: Radiation applicator
IPC: H01Q9/30
Filed: 2000-02-25
Abstract: Radiation applicators comprise an elongate device having an antenna (240) at their tip for coupling radiation into biological tissue and a dielectric body (250) surrounding the antenna so as to enhance transmission of radiation in the forward direction. The body (250) may be cylindrical with the antenna (240) along its axis. The antenna may is lambda /2 in length and lambda /2 in radius. The tip (270) of the antenna (240) is rounded hemispherical with radius lambda /2 to enhance forward transmission of radiation.
Patent IL-145871-A0 (IL)
Title: An oral formulation for ileum administering comprising an inhibitor compound of the ileal bile acid transport
IPC: A61K31/554
Filed: 2000-04-19
Abstract: An oral pharmaceutical formulation comprising an inhibitor compound of the ileal bile acid transport (IBAT inhibitor compound) and a therapeutically acceptable carrier characterised in that the formulation is designed to deliver the IBAT inhibitor compound in the ileum. The IBAT inhibitor compound can also be administered in combination with a bile acid binder to alleviate possible side effects of therapy with IBAT inhibitor compound, such as for instance diarrhoea. The bile acid binder may be formulated for colon release.
Patent IL-150920-A0 (IL)
Title: 2,4,di(hetero-)arylamino(-oxy)-5-substituted pyrimidines as antineoplastic agents
IPC: A61K31/506
Filed: 2001-02-26
Abstract: Pyrimidine derivatives of formula (I) wherein Q<SUB>1</SUB>, Q<SUB>2</SUB>, G and R<SUP>1 </SUP>are as defined within; and pharmaceutically acceptable salts and in vivo hydrolysable esters thereof are described. Processes for their manufacture, pharmaceutical compositions and their use as cyclin-dependent serine/threonine kinase (CDK) and focal adhesion kinase (FAK) inhibitors are also described.
Patent IL-154755-A0 (IL)
Title: Antitumor theraphy comprising distamycin derivatives
IPC: A61K31/40
Filed: 2001-09-21
Abstract: The present invention relates to an administration schedule comprising the intravenous administration of a alpha-halogen-acryloyl distamycin derivative, or a pharmaceutically acceptable salt thereof. The above administration allows the treatment of a variety of tumors in mammals.
Patent IL-160277-A0 (IL)
Title: Rotary piston machine
Inventor: SCHAPIRO BORIS
IPC: F01C1/10
Filed: 2002-08-08
Abstract: A rotary piston machine having a housing defining a prismatic chamber the cross section of which forms an oval of odd order. A rotary piston is guided in the chamber and, in each position, subdivides the chamber into two working chambers. Piston-fixed instantaneous axes of rotation of the rotary piston are defined in a center plane. The rotary piston, in each interval of movement, is rotating with one of opposite nappe sections in an inner wall section about an associated instantaneous axis of rotation and is sliding with the opposite nappe section along the opposite second inner wall section of the chamber and is reaching a stop position there.
Patent IL-172982-A0 (IL)
Title: Antibodies and ca6 antigen specific cytotoxic conjugates and pharmaceutical compositions containing the same
IPC: C07K16/30
Filed: 2006-01-05
Abstract: Cytotoxic conjugates comprising a cell binding agent and a cytotoxic agent, therapeutic compositions comprising the conjugate, methods for using the conjugates in the inhibition of cell growth and the treatment of disease, and a kit comprising the cytotoxic conjugate are disclosed are all embodiments of the invention. In particular, the cell binding agent is a monoclonal antibody, and epitope-binding fragments thereof, that recognizes and binds the CA6 glycotope. The present invention is also directed to humanized or resurfaced versions of DS6, an anti-CA6 murine monoclonal antibody, and epitope-binding fragments thereof.
Patent IL-176268-A0 (IL)
Title: Use of alginate matrices to control cell growth
IPC: A61F2/02
Filed: 2006-06-12
Abstract: Methods of inhibiting proliferation of a plurality of proliferating cells are disclosed. Methods of inhibiting cell overgrowth on compositions that are in an animal's body are disclosed. Methods of inhibiting cell overgrowth on a device that is in an animal's body are disclosed. Devices that have on their exterior surface an alginate matrix that comprises Strontium are disclosed. Compositions comprising an alginate body and alginate sheets that each comprise a single layer of cells coating the exterior surface of the alginate body are disclosed. Methods of preparing an artificial tissue are disclosed. Devices comprising cells encapsulated within an alginate matrix and/or maintained as a monolayer on an alginate body, and methods of making and using the same are disclosed. Methods of coating compositions and devices are disclosed.
Patent IL-178062-A0 (IL)
Title: Process for preparing cyclohexanediacetic acid monoamide
IPC: C07D221/20
Filed: 2006-09-13
Abstract: A new process is described for synthesising cyclohexanediacetic acid monoamide, a key compound in the synthesis of grabapentin precursors. The process of the invention is characterised by reacting cyclohexanone with cynoacetamide and immediately after, with a suitable malonic acid ester. A new intermediate (5-cyano-2,4-dioxo-3-azaspiro[5,5]undecane-1-carboxylic acid ester) is obtained which is convertible, under mild reaction conditions, into cyclohexanediacetic acid monoamide.
Patent IL-182320-A0 (IL)
Title: Collagen producing plants and methods of generating and using same
Filed: 2007-03-29
Abstract: The present invention relates to a method of producing collagen in a plant or an isolated plant cell comprising expressing in the plant or the isolated plant cell at least one type of a collagen alpha chain and exogenous P4H in a manner enabling accumulation of said at least one type of said collagen alpha chain and said exogenous P4H in a subcellular compartment devoid of endogenous P4H activity, thereby producing the collagen in the plant.
Patent IL-183454-A0 (IL)
Title: Method and device for computing computer-generated video holograms
Filed: 2007-05-28
Abstract: A method of computing a hologram by determining the wavefronts at the approximate observer eye (OE) position that would be generated by a real version of an object to be reconstructed. In normal computer generated holograms, one determines the wavefronts needed to reconstruct an object; this is not done directly in the present invention. Instead, one determines the wavefronts at an observer window (OW) that would be generated by a real object located at the same position of the reconstructed object (3D-S). One can then back-transform these wavefronts to the hologram to determine how the hologram needs to be encoded to generate these wavefronts. A suitably encoded hologram (HA) can then generate a reconstruction of the three-dimensional scene (3D-S) that can be observed by placing one's eyes at the plane (OP) of the observer window (OW) and looking through the observer window (OW).
Patent IL-186680-A0 (IL)
Title: Method for producing methylglycine-n,n-diethanoic acid trialkalimetal salts with a low by-product content
Filed: 2007-10-16
Abstract: The invention relates to a process for preparing low-by-product, light-color methylglycine-N,N-diacetic acid tri(alkali metal) salt by alkaline hydrolysis of methylglycinediacetonitrile (MGDN), comprising the steps in the sequence (a) to (f): (a) mixing of MGDN with aqueous alkali at a temperature of ≰30° C.; (b) allowing the aqueous alkaline MGDN suspension to react at a temperature in the range from 10 to 30° C. over a period of from 0.1 to 10 h to form a solution; (c) allowing the solution from step (b) to react at a temperature in the range from 30 to 40° C. over a period of from 0.1 to 10 h; (d) optionally allowing the solution from step (c) to react at a temperature in the range from 50 to 80° C. over a period of from 0.5 to 2 h; (e) optionally allowing the solution from step (c) or (d) to react at a temperature in the range from 110 to 200° C. over a period of from 5 to 60 min; (f) hydrolysis and removal of ammonia of the solution obtained in step (c), (d) or (e) by stripping at a temperature of from 90 to 105° C.
Patent IL-188716-A0 (IL)
Title: Method for preparing 4??-amino-4'-dimethyl-4-
Filed: 2008-01-10
Abstract: The invention relates to a method for synthesizing 4β-amino-4′-demethyl-4-desoxypodophyllotoxin of formula (1), characterized by comprising the following successive steps: a) reacting, in a pure weak acid or in a mixture consisting of acid, water and of organic solvent, without another solvent, at a temperature higher than the ambient temperature, thiourea with 4β-halogenoacetamido-4′-demethyl-4-desoxypodophyllotoxin, and; b) recovering the 4β-amino-4′-demethyl-4-desoxypodophyllotoxin.
Patent IL-189615-A0 (IL)
Title: Melanoma vaccine and methods of making and using same
IPC: A61K38/20
Filed: 2008-02-19
Abstract: An immunotherapeutic vaccine providing antigen presenting cells that have be en pulsed with a disrupted cell preparation which includes enucleated cytosol a nd cell membranes of cancer cells infected with a recombinant vaccinia virus encoding at least one immunostimulating molecule. In a preferred embodiment,  the vaccine includes autologous dendritic/monocytic cells (DC/M) that presen t a mixture of antigens (present in the enucleated cytosol and cell membranes)  from melanoma cell lines that have been infected with a recombinant vaccinia  virus encoding IL-2. In another of the preferred embodiments, the enucleated  cytosol and cell membranes are from melanoma cells harvested from the patien t to be treated. A method of making the vaccine and methods of using the vacci ne to stimulate an anti-cancer immune response and to treat a patient with a cancer are also described.
Patent RO-129787-A0 (RO)
Title: System for wall lining with stoneware and glass
Inventor: IACOBAN GHEORGHIŢĂ
IPC: E04F21/00
Filed: 2014-04-23
Abstract: The invention relates to a system for lining walls and floors with stoneware or glass slabs attached with adhesive or silicone. According to the invention, the system consists of a support or spacer for the lateral side of the stoneware slabs (), the height of which is variable depending on the thickness of the slabs (), the support being placed between the slab () supporting the slabs () from the back and the slab () supporting the slabs () from the front, where the slab () has a handle () attached to its top part in order to enable the fine adjustment of flatness.
Patent RO-135871-A0 (RO)
Title: Method for inducing subcutaneous vascularization by using vegf-producing primary human liver cells
Inventor: DIMA SIMONA OLIMPIA
IPC: A61P5/50
Filed: 2022-03-28
Abstract: The invention relates to a method of increasing survival and the functionality of implants by stimulating local vascularization in poorly vascularized (subcutaneous) situses with applicability in regenerative medicine for patients with diabetes. According to the invention, the method consists of: producing adult liver cells, infecting them with pancreatic transcription factors in order to induce transdifferentiation of the infected cells, co-implanting the cells in vivo at the subcutaneous level, in an immunodeficient murine medium, with VEGFA co-producing and secreting cells. The VEGFA-producing cells are generated in vitro 2 days prior to in-vivo implantation. Local production and secretion of VEGFA induces vascularization at the implantation site.
Patent MW-4486-A1 (MW)
Title: Technical hydrogen
IPC: C01B3/58
Filed: 1986-06-04
Abstract: A PSA based process for the production of technical hydrogen wherein the feed to the PSA contains nitrogen and carbon monoxide with a hydrogen/(carbon monoxide + nitrogen) volume ratio in the range 1.2 to 4 and a nitrogen/carbon monoxide volume ratio of at least 10. The adsorption step in the PSA stage is stopped when the integrated nitrogen content of the unadsorbed product is 1 to 10% by volume. The raw gas fed to the PSA is preferably made by a primary reforming a hydrocarbon feedstock with steam followed by secondary reforming followed by shift and water removal: the heat required for primary reforming is preferably supplied by the secondary reformer outlet gas. The PSA waste gas is preferably combusted in a gas turbine driving the secondary reformer air compressor.
Patent IE-910911-A1 (IE)
Title: Heterovesicular liposomes
Inventor: KIM SINIL
IPC: B01J13/02
Filed: 1991-03-19
Abstract: Disclosed are heterovesicular liposomes containing different biological compositions (14, 14a) each encapsulated in separate chambers of the liposomes, having defined size distribution, adjustable internal chamber size and number, methods of making them and treatment of patients with them. The preparation process includes the addition of composition to first lipid component in the vial to obtain an emulsion, the addition of composition to second lipid component in the vial to obtain a second emulsion and mixing these emulsions to form a chimeric emulsion.