baber/WOPTO huggingface dataset:
Patent CA-2583799-A1 (CA)
Title: Methods for increasing the diversity of monoclonal antibodies produced against an antigen
Inventor: CUMMING DALE ANTHONY
IPC: C07K16/28
Filed: 2005-10-12
Abstract: The present invention relates to methods for increasing the diversity of monoclonal antibodies produced against an antigen. The methods of the invention utilize immunization of a murine host defective in one or more enzymes involved in a post-translational modification of a polypeptide or a modification of a lipid, wherein said modification is exposed on a cell surface. The invention also relates to monoclonal antibodies produced by these methods and which are not produced when a normal mouse is immunized with the same antigen. The invention further relates to compositions comprising these monoclonal antibodies, as well as to such monoclonal antibodies bound or conjugated to a toxin, a detectable marker or to a solid support.
Patent CA-2584340-A1 (CA)
Inventor: BACON NED ALAN
IPC: F17C3/00
Filed: 2005-10-18
Abstract: A low-temperature/cryogenic liquid-storage structure has an inner tank liner made of conventional low-temperature/cryogenic tank-quality plates with structural members that provide flexibility. The plates are mounted on connectors that accommodate movement of the liner with respect to the bearing wall.
Patent CA-2585897-A1 (CA)
Inventor: KATES LAWRENCE
IPC: H04N5/44
Filed: 2005-10-04
Abstract: A multimedia control system presents program schedule information to a user in a visually and intellectually-intuitive manner. The multimedia control system can be used to display programming information, control multimedia devices, control home automation devices, etc. In one embodiment, a control screen used to display programming information is configured as a touch screen to allow the user to select programming, control multimedia devices, or perform other functions by touching the screen. In one embodiment, the system uses a consistent, user-selectable, intuitive user interface. In one embodiment, programming information is dynamically updated to provide the user with current programming information, such as, for example, sports scores, commercial breaks, news stories, documentary contents, etc.
Patent CA-2587937-A1 (CA)
Inventor: SIMMONS WALTER N
IPC: C01B32/50
Filed: 2005-11-23
Abstract: This invention relates to a process for converting silica to polysilicate gels or hydrogels by combining an aqueous silica source with a CO2 feed stream as the gel initiator, whereby the reaction stream is propelled at high velocity and turbulence maintaining the CO2 uptake rate in the reaction stream. The invention also relates to a process for converting silica to polysilicate by pre-carbonating water at pressures of equal to or greater than 100 psig before initiating the polysilicate reaction.
Patent CA-2588151-A1 (CA)
Inventor: CROWDER TROY STACEY
IPC: A63C1/00
Filed: 2007-05-10
Abstract: A hockey skate includes a system for adjusting the position of a blade holder on the sole of a hockey skate. The system allows for both toe in and toe out adjustment as well as movement relative to the centerline. The system allows a player to try various positions and determine which positions produce superior skating performance relative to his foot, ankle and leg alignment. The skate includes a lace extension arrangement at an upper edge of a boot of the skate to define a variable pivoting slot accommodating forward and rearward pivoting of the user's leg about the ankle will provide lateral support.
Patent CA-2590875-A1 (CA)
Inventor: BARRALL GEOFFREY S
IPC: G06F11/10
Filed: 2005-11-04
Abstract: A storage system condition indicator and method provides a visual display representing the operating condition of a set of storage devices. Various operating conditions may be defined based on available storage capacity and capacity to store data redundantly. One or more indicators may be used to represent the operating condition of the set of storage devices. The indicator(s) may be used to indicate whether additional storage capacity is recommended and, in a storage array, which slot in the array should be updated with additional storage capacity.
Patent CA-2591384-A1 (CA)
Inventor: BOURGAULT GERARD
IPC: A01C5/06
Filed: 2007-06-12
Abstract: A method for seeding flax seeds and canola seeds includes: with a plurality of side banding furrow openers, depositing seeds into a corresponding plurality of seed furrows;  with each side banding furrow opener, depositing phosphate fertilizer in a corresponding side band in proximity to the seeds in the seed furrows; with a plurality of mid-row banding furrow openers, depositing nitrogen fertilizer, and optionally sulfur fertilizer, in fertilizer furrows where each fertilizer furrow is located substantially midway between adjacent seed furrows. An apparatus for practicing the method is provided as well.
Patent CA-2591990-A1 (CA)
Inventor: AMAITIS LEE M
IPC: G07F17/34
Filed: 2005-12-21
Abstract: A method for wagering, comprises receiving a bet regarding a spin of the reels of a slot machine. The method continues by determining a first symbol for a first reel of the slot machine based at least in part upon a first value and a second value. The first value is associated with a value of a digit of a first financial market indicator at a first point in time, and the second value is associated with the value of a digit of a second financial market indicator at the first point in time. The method continues by determining a second symbol for a second reel of the slot machine, and by determining a third symbol for a third reel of the slot machine. The method concludes by determining an outcome of the bet based at least in part upon the first symbol, the second symbol, and the third symbol.
Patent CA-2592748-A1 (CA)
Title: Hemostasis assay
Inventor: VAN HEERDE WAANDER LAURENS
IPC: C12Q1/56
Filed: 2006-01-09
Abstract: The invention relates to a hemostasis assay comprising the provision of a reaction mixture comprising a blood product to be tested, a trigger molecule for inducing thrombin generation, a thrombin-specific substrate that upon cleavage by thrombin produces a measurable thrombin-specific signal, a trigger molecule for inducing plasmin generation, a plasmin-specific substrate that upon cleavage by plasmin produces a measurable plasmin-specific signal, a phospholipid-containing surface and calcium ions, and determination of the amount of thrombin and the amount of plasmin generated in the reaction mixture in time starting at t=0 by measuring the thrombin-specific and plasmin-specific signals.
Patent CA-2593518-A1 (CA)
Title: Multi-bit driver with rotatable sleeve
Inventor: PETERS MICHAEL P
IPC: B25B21/00
Filed: 2007-07-12
Abstract: A rotary tool includes a tool holder, a reversible bit, and an outer rotatable sleeve. The tool holder includes a socket and a shank. The socket includes an opening extending rearwardly from an end thereof. The shank is integral with and extends rearwardly from the socket and includes a non-circular cross-section.  The reversible bit includes an inner sleeve, a first reversible bit driver, and a second reversible bit driver. The inner sleeve is disposed within the socket and rotates with the tool holder. One of the first and second bit drivers extends axially out of the socket opening. The outer rotatable sleeve is disposed over at least a portion of the socket and the bit driver extending axially out of the socket opening. The outer rotatable sleeve further includes a magnet in an end proximate the bit driver extending axially out of the socket opening.
Patent CA-2595300-A1 (CA)
Inventor: PRAMANIK PRANABES K
IPC: B32B15/00
Filed: 2006-02-15
Abstract: The invention concerns multilayered constructions useful for forming resistors and capacitors, for the manufacture of printed circuit boards or other microelectronic devices. The multilayered constructions comprise sequentially attached layers comprising: a first electrically conductive layer, a first thermosetting polymer layer, a heat resistant film layer, a second thermosetting polymer layer, and a nickel-phosphorus electrical resistance material layer electroplated onto a second electrically conductive layer.
Patent CA-2597151-A1 (CA)
Inventor: LI YUN
IPC: A61K48/00
Filed: 2007-08-31
Abstract: The invention provides a polynucleotide encoding an envelope protein comprising gp120 of human immunodeficiency virus-1 (HIV-1) having a mutation at amino acid residues 197-199 whereby a single N-linked glycan is removed. In a typical embodiment, the mutation replaces the asparagine (N) at residue 197 with another amino acid, such as glutamine (Q), creating an N197Q mutation. Because the N197 glycan is highly conserved among subtypes, this approach is applicable across HIV-1 isolates. The invention provides polypeptides, polynucleotides encoding the polypeptides, vectors, and recombinant viruses containing the polynucleotides, antigen-presenting cells (APCs) presenting the polypeptides, immune cells directed against HIV, and pharmaceutical compositions. The invention additionally provides methods, including methods for preventing and treating infection, for killing infected cells, for inhibiting viral replication, for enhancing secretion of antiviral and/or immunomodulatory lymphokines, and for enhancing production of neutralizing antibody.
Patent CA-2597178-A1 (CA)
Title: Safety shield for use with different diameter racking rods and an adaptor for use therewith
Inventor: HOAGLAND ELIHU IV
IPC: H02H3/00
Filed: 2006-02-07
Abstract: A protective shield that may be secured to an electrical racking rod of the type used for performing electrical work on various types of energized electrical equipment. The protective shield includes a transparent plate formed of an impact resistant, fire retardant material; a clamping mechanism secured to the plate and at least one adaptor for securing the racking rod to the plate. The adaptor is engaged by the clamping mechanism to secure the racking rod to the plate. The protective shield provides physical protection to workers when removing or resetting electrical circuit breakers by acting as a barrier between the worker and the equipment while providing complete visibility to the task being performed. A plurality of adaptors may be provided to enable the plate to be utilized with any one of a plurality of different diameter racking rods.
Patent CA-2600982-A1 (CA)
Title: Elliptical exercise device
Inventor: CHUANG LUNG FEI
IPC: A63B22/06
Filed: 2007-09-07
Abstract: An exercise device includes two cranks rotatably coupled to an upright support of a base, two handles pivotally coupled to the upright support, and two foot supports each having a front portion pivotally coupled to the pivot rod or an extended arm of the cranks with a link and each having a rear portion pivotally coupled to the rear portion of the base, and the lower portions of the handles are pivotally coupled to the foot supports to allow the moving stroke of the foot supports to be controlled by the handles. The handles may be pivotally coupled to the cranks with levers. A foot pedal may be pivotally supported on each of the foot supports and pivotally coupled to the handles.
Patent CA-2601938-A1 (CA)
Title: Transport of nano- and macromolecular structures into cytoplasm and nucleus of cells
Inventor: ROSENECKER JOSEPH
IPC: A61K47/48
Filed: 2006-02-15
Abstract: The present invention refers to novel conjugate molecules and their use or the transport of nano- and macromolecular structures into cells and/or the nucleus. More particularly, the present invention refers to conjugate molecules containing a carrier, preferably thiopyridyl moieties, and a cargo moiety. Thereby, the thiopyridyl moiety is bound to the cargo moiety to act as a carrier, particularly for efficient intracellular and/or intranuclear delivery of drugs, nano-or macromolecular structures, etc.. The novel conjugate molecules are provided for the manufacture of a medicament for gene therapy, apoptosis, or for the treatment of diseases such as cancer, autoimmune diseases or infectious diseases.
Patent CA-2606175-A1 (CA)
Inventor: ROSALES RODOLFO
IPC: B60G9/00
Filed: 2006-04-28
Abstract: A four-point wishbone-shaped linkage is disclosed for use in a suspension system. The wishbone-shaped linkage includes a base and two limbs that extend away from the base creating a large mouth open area between the limbs and base. The base includes a bar and bushing assembly extending laterally therethrough. Also disclosed are suspension systems incorporating the four-point wishbone-shaped linkage. The suspension system connects an axle to a vehicle chassis that has a first frame member extending longitudinally on one side of the chassis and a second frame member extending longitudinally on the opposite side of the chassis. The first and second frame hangers are mounted to the first and second frame member, respectively. A cross member connects the first and second frame hangers. In addition to the wishbone-shaped linkage, the suspension system includes first and second air springs connected to first and second frame members respectively and to the axle. A shock absorber is likewise connected to each frame member and axle. Torque rods are also included. One torque rod is pivotally connected to the axle and first frame hanger and a second torque rod is pivotally connected to the axle and second frame hanger. The wishbone-shaped linkage is pivotally connected to the axle and cross member.
Patent CA-2606441-A1 (CA)
Inventor: HALFORD KENNETH J
IPC: C09J7/29
Filed: 2006-04-26
Abstract: A multilayer protective film comprising a first layer, a second layer and a PSA layer. The first layer at least comprises a polyester-based polyurethane, a polycarbonate-based polyurethane or a combination or blend of both. The second layer at least comprises a polycaprolactone-based thermoplastic polyurethane. The PSA layer comprises a pressure sensitive adhesive. One major surface of the first layer is bonded to one major surface of the second layer, and the PSA layer is bonded to an opposite major surface of the second layer such that the second layer is sandwiched between the first layer and the PSA  layer.
Patent CA-2606542-A1 (CA)
Inventor: TAURIAN ANDREA
IPC: F24H3/00
Filed: 2006-05-05
Abstract: Space-heating apparatus, comprising a radiator with a fluid to transfer the heat and an electric heating element, general means for adjusting and controlling grouped together in two separate assemblies, in which a first assembly comprises: control elements that can be operated from the outside and selectively set by the user, a transmission means for modulating/coding signals that represent the settings in said control elements, and for transmitting said signals to a second assembly that comprises: adjusting elements and respective control means, relating at the electric current supplied to said heating element, and means for receiving and for demodulating the signals coming from said transmission means; said first assembly is arranged on the upper part of the apparatus, and said transmission means and receiving means transmit by radio-frequency or infrared signals.
Patent CA-2606592-A1 (CA)
Title: Methods for analysis of pressure response in underground formations
Inventor: GOODE PETER
IPC: E21B47/06
Filed: 2005-05-10
Abstract: A method of analysing a reservoir pressure in an underground formation surrounding a well, comprising: determining the permeability of mud cake on the wall of the well in the region in which the pressure measurement is made;  determining the thickness of mud cake on the well of the well in the region in which the pressure measurement is made; determining the hydrostatic pressure in the well in the region in which the pressure measurement is made; measuring the formation pressure at the wall of the well; calculating a pressure decay index from the mud cake permeability and thickness, the hydrostatic pressure and the measured pressure; and using the pressure decay index to analyse the measured pressure to derive the reservoir pressure.
Patent CA-2607100-A1 (CA)
Inventor: HAUT RICHARD CARL
IPC: E21B43/10
Filed: 2000-03-07
Abstract: An apparatus is provided which includes first and second tubular members, wherein the inner diameter of the first tubular member is substantially equal to the inner diameter of the second tubular member, and the first and second tubular members are coupled by the process of deforming a portion of the second tubular member into contact with a portion of the first tubular member. Also provided is a method for forming a wellbore by the process of drilling the wellbore, wherein a tubular liner is positioned within the wellbore and formed by the process of extruding the tubular liner off of a mandrel while drilling the wellbore.
Patent CA-2609137-A1 (CA)
Inventor: TERZIAKIN MEHMET
IPC: B21D43/05
Filed: 2005-05-16
Abstract: A device including at least one transformer (1) with primer (N1) / seconder (N2) coil ratio more than one and including a control unit (9) used to control timing and magnetute of the primer current is employed to heat a metal workpiece (4) to be subjected a subsequent forming operation. An homopolar DC  generator can also be used as current source for current heating preparing workpiece for forming operation. Subsequent heating, forming and cooling processes of the metal workpiece are carried out in a controlled manner by a central synchronization unit. This process can be applicated in hot metal bulk forging, sheet forming and hot tube blowforming.
Patent CA-2613511-A1 (CA)
Title: Stationary virtual cycle system and method for operating the same
Inventor: TOMES CHRISTOPHER
IPC: A63B22/06
Filed: 2006-06-23
Abstract: The invention is directed generally to a method and apparatus for providing a stationary cycle, and more particularly to methods and devices for providing a user, such as a child, with a stationary cycle to navigate through a virtual world displayed to the user. More specifically, the invention allows a user to navigate within a virtual world by controlling a stationary cycle, thereby combining the interaction of a video game environment with the exercise afforded on a cycle. The user pedaling the cycle and controlling the handle bars. Based on these actions, the user can control navigation within the virtual world.
Patent CA-2616419-A1 (CA)
Title: Method and system of integrated mine planning
Inventor: STEFFENS GEOFFREY JOHN
IPC: G06Q50/00
Filed: 2006-08-07
Abstract: A system and method for facilitating integrated mine planning in a mining operation. The system has a data module to store data objects. The system also has a management module in communication with the data module and the management module is configured with at least one workflow having a series of interdependent processing steps representative of planning steps for a mine plan. The management module controls the accessibility of one or more users to each of the steps within the at least one workflow. The at least one user is able to obtain one or more data objects from the data store, under the control of the management module, to process the one or more data objects to perform at least one processing step in the at least one workflow using a proprietary expert software solution.
Patent CA-2616539-A1 (CA)
Title: Direct aminolysis
Inventor: LI ZHENGONG BRYAN
IPC: C07D205/04
Filed: 2006-08-21
Abstract: In some aspects, the present invention provides a method of preparing a compound of the formula (I) comprising reacting a mesylate compound of the formula (II) by direct aminolysis with a reagent comprising ammonia. The reaction is preferably carried out in a solvent, such as an alcohol, and is preferably carried out in a sealed vessel such as a Parr reactor or the like.
Patent CA-2618796-A1 (CA)
Title: Peptides for treatment and diagnosis of autoimmune disease
Inventor: MATOSSIAN-ROGERS ARPI
IPC: A61K39/00
Filed: 2006-08-09
Abstract: There are provided peptides derived from antibodies with reactivity against a GPI linkage epitope and functionally-equivalent ligands. These peptides can be used in the therapy and diagnosis of a variety of diseases, all of which are considered to be caused by the inappropriate presence in the body of autoantibodies which are reactive with GPI linkage epitopes. There is also described a mechanism of action of these autoantibodies which compromises the organism, so causing disease, and a method of prevention of disease and detection of the autoantibody.
Patent CA-2619868-A1 (CA)
Inventor: MORGAN JOHN DOUGLAS
IPC: B41J2/165
Filed: 2006-07-10
Abstract: A printhead maintenance assembly for maintaining a printhead in an operable condition is provided. The maintenance assembly comprises: (a) a maintenance roller having an elastically deformable contact surface for sealing engagement with an ink ejection face of the printhead; (b) an engagement mechanism for moving the roller between a first position in which the contact surface is sealingly engaged with the face, and a second position in which the contact surface is disengaged from the face; and (c) a cleaning mechanism for cleaning the contact surface. The cleaning mechanism comprises a motor for rotating the maintenance roller, and an ink removal system for removing ink from the contact surface when the maintenance roller is rotated.
Patent CA-2620091-A1 (CA)
Title: Balsalazide formulations and manufacture and use thereof
Inventor: LOCKHART JOSEPH
IPC: B01F23/70
Filed: 2006-08-24
Abstract: The invention relates to formulations and dosage schedules of balsalazide. The invention further relates to methods of producing pharmaceutical formulations of balsalazide.
Patent CA-2620275-A1 (CA)
Title: Non-steroidal antiandrogens
Inventor: KADNIKOV DMITRY V
IPC: A61K31/40
Filed: 2006-08-28
Abstract: The invention provides non-steroidal ligands for the androgen receptor, methods for making non-steroidal ligands of the androgen receptor, compositions of non-steroidal ligands of the androgen receptor and methods of using non-steroidal ligands and compositions of non-steroidal ligands of the androgen receptor for treating or preventing diseases (e.g., prostate cancer) associated with androgen binding to the androgen receptor.
Patent CA-2624903-A1 (CA)
Inventor: GUZMAN CARLOS A
IPC: A61K31/70
Filed: 2006-11-08
Abstract: The present invention relates to new adjuvants and the uses in pharmaceutical compositions, like in vaccines. In particular, the present invention provides new compounds useful as adjuvants and/or immunomodulators for prophylactic and/or therapeutic vaccination in the treatment of infectious diseases, inflammatory diseases, autoimmune diseases, tumours, allergies as well as for the control of fertility in human or animal populations. The compounds are particularly useful not only as systemic, but preferably as mucosal adjuvants.  In addition, the invention relates to its uses as active ingredients in pharmaceutical compositions.
Patent CA-2626083-A1 (CA)
Title: Prevention de perte de paquets pendant le transfert par le biais d'une architecture de noeuds tampons geres
Inventor: YAQUB RAZIQ
IPC: H04J3/22
Filed: 2006-10-11
Abstract: Dans des modes de réalisation préférés, un sous-système de réseau sans fil met en place la mise au tampon de données de paquets de données transmises vers les noeuds mobiles. Le système est transparent vis-à-vis du noeud mobile, et de cette manière le noeud mobile n'est pas nécessaire pour demander un service au réseau et ne négocie pas les paramètres de service avec le réseau. Un démarrage EAPON et des messages de mise à jour obligatoire lancent et terminent la mise au tampon et commencent aussi la pré-authentification de manière à lisser le rapport de transfert, respectivement.
Patent CA-2627380-A1 (CA)
Inventor: PATT RAYMOND FELIX
IPC: F02C7/36
Filed: 2008-03-20
Abstract: A power take-off system (100,400,500) for a gas turbine engine assembly (10) is provided. The gas turbine engine includes a first spool (40) and a second spool (42), the power take-off system including a starter (102) coupled to the second spool, and a clutch assembly (200) coupled between the starter and the first spool, the clutch assembly configured to couple the first spool to the starter when starting the gas turbine engine assembly.