baber/WOPTO huggingface dataset:
Patent CA-3098382-A1 (CA)
Inventor: WATSON ANDRE RONALD
IPC: A61K9/14
Filed: 2019-04-24
Abstract: Provided are methods and compositions for genome editing using a delivery vehicle with multiple payloads. In some embodiments the delivery vehicle includes a payload that includes (a) one or more sequence specific nucleases that cleave the cell's genome or one or more nucleic acids encoding same, (b) a first donor DNA, which includes a nucleotide sequence that is inserted into the cell's genome, where insertion of said nucleotide sequence produces, in the cell's genome at the site of insertion, a target sequence (e.g., an attP site) for a site-specific recombinase; (c) the site-specific recombinase (or a nucleic acid encoding same) (e.g., FC31, FC31 RDF, Cre, FLP), where the site-specific recombinase recognizes said target sequence; and (d) a second donor DNA, which includes a nucleotide sequence that is inserted into the cell's genome as a result of recognition of said target sequence by the site-specific recombinase.
Patent CA-3098862-A1 (CA)
Title: Modes de fonctionnement utilisant un systeme de freinage pour un vehicule tout terrain
Inventor: SCHEUERELL ALEX R
IPC: B62D6/00
Filed: 2019-05-02
Abstract: L'invention concerne un véhicule tout terrain pouvant comprendre un châssis et une pluralité d'éléments de mise en prise avec le sol soutenant le châssis. Chacun de la pluralité d'éléments de mise en prise avec le sol peut être conçu pour tourner autour d'un essieu. Le véhicule tout terrain peut en outre comprendre un ensemble groupe motopropulseur soutenu par le châssis et un système de freinage (par exemple un système de freinage antiblocage (ABS)) comprenant une unité de commande hydraulique et électrique (HECU) fonctionnellement couplée à la pluralité d'éléments de mise en prise avec le sol et conçue pour générer un lacet pour réduire un rayon de braquage du véhicule tout terrain. Le HECU peut être conçu pour commander la pression de freinage à la pluralité d'éléments de mise en prise avec le sol indépendamment d'une entrée du conducteur indiquant un événement de freinage.
Patent CA-3100240-A1 (CA)
Title: Systemes, dispositifs et procedes pour le deploiement et l'imagerie precis d'un implant dans l'uretre prostatique
Inventor: BLY AUSTIN MICHAEL
IPC: A61F2/95
Filed: 2019-05-16
Abstract: L'invention concerne des systèmes, des dispositifs et des procédés pour l'administration d'un implant dans l'urètre prostatique. Des modes de réalisation de systèmes d'administration peuvent comprendre un dispositif d'administration destiné à être inséré dans le patient et un dispositif de commande proximal destiné à être utilisé pour commander la libération de l'implant à partir du dispositif de distribution.
Patent CA-3107380-A1 (CA)
Inventor: PERFLER ENRICO
IPC: A61L27/38
Filed: 2019-08-05
Abstract: The present invention refers to a model for in-vitro simulation of the behaviour of dysfunctional human vessels, such as for example vessels affected by aneurysm, stenosis or sclerosis plaques, as an instrument for testing medical devices and drugs with the aim of verifying effectiveness and safety thereof prior to use thereof on humans. Specifically, the present invention refers to an in vitro model of a substantially tubular-shaped vascular structure having dysfunctional anatomical and physiological characteristics simulating the same vascular structure of a healthy subject whose vascular structure has been damaged or deformed or deteriorated due to a damage selected from among the group comprising or, alternatively, consisting of aneurysm, stenosis, sclerosis plaques, forms of tumours or cardiomyopathies having the characteristics as claimed in the attached claims. Furthermore, the present invention also refers to a reliable and reproducible industrialisation process for eliminating air bubbles for producing an engineered vascular tissue for the in vitro test of medicinal products for human use and veterinarian products for animal use.
Patent CA-3107821-A1 (CA)
Title: Gutter cleaners and methods associated therewith
Inventor: HOLMAN CHRISTOPHER A
IPC: B08B5/02
Filed: 2021-02-03
Abstract: A gutter cleaner comprising: a fan assembly; a guide configured to at least partially support the fan assembly on a gutter, wherein the guide comprises a skid configured to slide along the gutter; a handle coupled to the fan assembly at a location adjacent to a first axial end of the handle; and a battery port disposed at a location adjacent to a second axial end of the handle, the second axial end of the handle being opposite the first axial end of the handle, wherein the gutter cleaner is supportable via the handle by an operator located at an elevation below the gutter, and wherein the gutter cleaner has an approximately neutral operational buoyancy.
Patent CA-3108468-A1 (CA)
Inventor: KANG JUNG WON
IPC: H04N19/513
Filed: 2019-08-06
Abstract: An image decoding method is disclosed in the present specification. An image decoding method of the present invention comprises: a step of generating a candidate list including motion information derived from a temporal neighboring block and a spatial neighboring block adjacent to a current block; a step of deriving motion information of the current block by using the candidate list; a step of generating a prediction block of the current block by using the derived motion information; and a step of updating the derived motion information in a motion information list, wherein the step of generating the candidate list comprises generating the candidate list including at least one piece of motion information included in the motion information list updated in a block encoded before the current block.
Patent CA-3109933-A1 (CA)
Title: Murphy bed chest
Inventor: VALONE MARK
IPC: A47C17/38
Filed: 2019-08-28
Abstract: A folding bed chest system includes a cabinet having a front panel assembly movable from a closed position to an opened position, wherein when in the open position the front panel assembly is supportive of a mattress located thereon. A drawer assembly is freely movable into an out of a drawer opening located below the front panel assembly. The drawer assembly is configured such that the front panel assembly is movable from the closed position to the opened position when the drawer assembly is located fully in the drawer opening.
Patent CA-3110997-A1 (CA)
Title: Oral film compositions and dosage forms having precise active dissolution profiles
Inventor: SCHOBEL ALEXANDER MARK
IPC: A61K31/551
Filed: 2019-09-05
Abstract: An oral film in an individual unit dose for delivery of one or more actives is disclosed herein, the film having a precisely calculated and controlled active dissolution profile. A wide variety of actives may be used, including, for example, clobazam, diazepam, or riluzole. Also disclosed are methods of treating a variety of diseases and conditions, for example., epilepsy and seizures, by administering the oral film disclosed herein.
Patent CA-3111007-A1 (CA)
Inventor: KERAMATI NOORI NARIMAN
IPC: A61M15/00
Filed: 2019-06-26
Abstract: A disposable capsule, containing herbal product such as cannabis, can be used with a vaporizer for vaporizing the volatile constituents. The limited battery capacity of portable vaporizers necessitates efficient energy use in order to generate vapor from the herbal product. This is achieved through various features of the invention. Aided by airtightness of the vaporizer capsule connection, the airflow through the capsule can be guided in a controlled fashion. In fact, the capsule (1) is for use in a vapor producing device, the capsule (1) being filled with a herbal product (30) and comprising a shell (202), an upstream part (40) and a downstream part (41), wherein an inlet orifice (401) is in the upstream part (40) and/or in the shell (202) and an outlet orifice (411) is in the downstream part (41), the inlet orifice (401) and the outlet orifice (411) comprising a multitude of perforations (10), and wherein a flow-through-area A2, being a combined surface area of the perforations (10) of the outlet orifice (411), is larger than a flow-through-area Al, being a combined surface area of the perforations (10) of the inlet orifice (401).
Patent CA-3114072-A1 (CA)
Inventor: HELLEWELL KENDELL B
IPC: C12N5/04
Filed: 2021-04-01
Abstract: _ The invention provides seed and plants of corn line SHY-6RSNL196. The invention thus relates to the plants, seeds, and tissue cultures of corn line SHY-6RSNL196 and to methods for producing a corn plant produced by crossing such plants with themselves or with another corn plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants.
Patent CA-3114837-A1 (CA)
Inventor: BOUCHARD GUY
IPC: F02C7/36
Filed: 2021-04-13
Abstract: A gas turbine engine, has: a shaft rotatable about a central axis and engaged at an end thereof to a rotatable load via a spline; a reference tube circumferentially extending around the shaft, the reference tube secured at a first end to the shaft for rotation therewith and a second end free relative to the shaft for measuring a deformation of the shaft, the reference tube defining at least one tube aperture therethrough; an oil nozzle fluidly connected to a source of lubricant, the oil nozzle defining an exit flow axis intersecting the at least one tube aperture for injecting oil through the reference tube, the shaft defining at least one shaft aperture extending therethrough, the oil nozzle aligned with the spline via the at least one tube aperture and the at least one shaft aperture.
Patent CA-3115291-A1 (CA)
Title: Procedes d'expansion de cellules stromales mesenchymateuses
Inventor: SHPALL ELIZABETH
IPC: A61K38/19
Filed: 2019-10-04
Abstract: La présente invention concerne des procédés d'expansion de populations de cellules stromales mésenchymateuses (MSC) comprenant le traitement d'une population de MSC dérivée de tissu de cordon avec un cocktail de cytokines de pré-activation. L'invention concerne en outre des procédés de traitement de troubles immunitaires avec les MSC
Patent CA-3115849-A1 (CA)
Inventor: HU OLIVER YOA-PU
IPC: G01N27/26
Filed: 2018-10-19
Abstract: A galactose rapid detection system has a galactose composition including a galactose, a buffer solution and an 0~99%antioxidant, which enters a human body after metabolism and produces a biological sample; a test strip or a filter paper, comprising an enzyme, the enzyme would react with the biological sample producing a electrochemical information; a meter including a power supply unit for providing a signal; a connector for receiving the signal provided by the power supply unit, transmitting the signal to the test strip or the filter paper, wherein the signal reacting with the electrochemical information produce a corresponding response signal, and the connector transmit the corresponding response signal to the meter; a calculation unit for calculating the corresponding response signal; an A/D convertor for receiving the corresponding response signal from the calculation unit, transforming the corresponding response signal into a digital reaction signal calculated by the calculation unit; and a processor for processing the digital reaction signal a display for displaying the digital reaction signal; and a digital terminal for receiving the digital reaction signal.
Patent CA-3117251-A1 (CA)
Inventor: TANG WANFU
IPC: F24F8/80
Filed: 2019-10-21
Abstract: L'invention concerne également un système et un procédé d'élimination de poussière de l'air (101), comprenant une entrée de système d'élimination de poussière, une sortie de système d'élimination de poussière, et un dispositif de champ électrique. Le dispositif de champ électrique comprend une entrée de dispositif de champ électrique (1011), une sortie de dispositif de champ électrique (1012), une cathode de champ électrique d'élimination de poussière (10142), et une anode de champ électrique d'élimination de poussière (10141). La cathode de champ électrique d'élimination de poussière (10142) et l'anode de champ électrique d'élimination de poussière (10141) sont utilisées pour générer un champ électrique d'élimination de poussière ionisant. Le présent système d'élimination de poussière d'air (101) et le procédé peuvent éliminer efficacement la matière particulaire de l'air.
Patent CA-3122672-A1 (CA)
Title: Asymmetric lateral avalanche photodetector
Inventor: KNIGHTS ANDREW
IPC: H01L31/0232
Filed: 2021-06-17
Abstract: ABSTRACT Avalanche photodetector devices are disclosed in which spatial asymmetry is employed to preferentially enhance avalanche multiplication of electrons. In some example embodiments, an avalanche photodetector device includes p-doped and n-doped regions and a central waveguide region, where the p-doped region is laterally offset from the central waveguide by a first lateral offset region, and where the n-doped region is laterally offset from the central waveguide by a second lateral offset region. The first and second lateral offset regions are asymmetrically defined such that impact ionization and avalanche multiplication of electrons in the second laterally offset region is enhanced relative to that of holes in the first laterally offset region. In some example implementations, the asymmetry may be provided by a difference in relative heights and/or lateral spatial extends (widths) of the lateral offset regions, such that the electric field, or a spatial extent associated therewith, is enhanced for electrons.   Date Recue/Date Received 2021-06-17
Patent CA-3125142-A1 (CA)
Title: Domperidone antineurodegenerative combinations and use
Inventor: CHASE THOMAS N
IPC: A61K31/4747
Filed: 2019-12-03
Abstract: A pharmaceutical combination comprising domperidone, a 6-propylamino-4,5,6,7-tetrahydro-1,3-benzothiazole-2-amine and at least one of fluoxetine, zonisamide or a statin, for the treatment of protein misfolding neurodegenerative diseases.
Patent CA-3126158-A1 (CA)
Title: Procedes et compositions pour reguler la production d'eau en exces
Inventor: SAINI RAJESH KUMAR
IPC: E21B43/25
Filed: 2020-01-13
Abstract: Des modes de réalisation concernent des procédés et des compositions pour réguler la production d'eau en excès pour la récupération d'hydrocarbures. Selon un mode de réalisation, le procédé comprend une composition de fluide de traitement. La composition de fluide de traitement comprend un monomère et un acide latent. La composition de fluide de traitement est introduite en fond de trou où elle est positionnée dans une région contenant de l'eau d'une formation contenant des hydrocarbures. Un catalyseur acide est formé par hydrolyse ou décomposition de l'acide latent dans la région contenant de l'eau. Le catalyseur acide est utilisé pour polymériser le monomère pour former une résine. La résine empêche l'eau de s'infiltrer de la région de contenant de l'eau dans le puits de forage.
Patent CA-3127291-A1 (CA)
Inventor: SIGURDSSON STEINTHOR
IPC: A61K9/00
Filed: 2020-02-11
Abstract: La présente invention concerne un cnidimoside A destiné à être utilisé dans le traitement d'affections urinaires telles qu'une vessie hyperactive et des syndromes apparentés. L'invention concerne également des procédés de traitement d'une vessie hyperactive à l'aide de cnidimoside A. Le composé peut être administré sous forme purifiée ou en tant qu'extrait de plante.
Patent CA-3131586-A1 (CA)
Title: Method and apparatus for creating a scored hinge in a hip or ridge cap shingle
Inventor: LEITCH OLAN T
IPC: E04D1/30
Filed: 2021-09-17
Abstract: A cap shingle configured to be installed over a hip or ridge of a roof structure, and a method for creating scored hinge lines in hip and ridge cap shingles during manufacturing while minimizing the likelihood of breakage along the scored hinge lines due to lane tension are disclosed. The method includes forming score lines with a scoring cylinder across lanes of shingle material just before the lanes are cut into individual cap shingles with a pattern cutter. The scoring cylinder and pattern cutter are controlled so that the score lines are consistently applied along the centerlines of the cap shingles.
Patent CA-3136760-A1 (CA)
Inventor: CHOI BYEONGDOO
IPC: H04N13/00
Filed: 2020-11-09
Abstract: A method of generating an encoded video bitstream using at least one processor, including making a first determination regarding whether a current layer of a current picture is an independent layer; making a second determination regarding whether reference picture resampling is enabled for the current layer; based on the first determination and the second determination, disabling wrap-around compensation for the current layer; and encoding the current layer without the wrap-around compensation.
Patent CA-3137412-A1 (CA)
Title: Electrosurgical system
Inventor: HANCOCK CHRISTOPHER
IPC: A61B18/18
Filed: 2020-04-28
Abstract: Various embodiments provide an electrosurgical system for treating biological tissue. The system comprises: an electrosurgical generator configured to supply pulsed microwave energy; and an electrosurgical instrument. The electrosurgical instrument comprises a flexible coaxial cable arranged to convey the pulsed microwave energy; and a radiating tip portion connected at a distal end of the coaxial cable and configured to receive the pulsed microwave energy. The radiating tip portion has a maximum outer diameter that is 1.0 mm or less, and wherein the maximum outer diameter of the radiating tip portion is smaller than an outer diameter of the coaxial cable. Also, the radiating tip portion comprises: a proximal coaxial transmission line for conveying the pulsed microwave energy; and a distal needle tip mounted at a distal end of the proximal coaxial transmission line, the distal needle tip being arranged to deliver the pulsed microwave energy into biological tissue.
Patent CA-3139284-A1 (CA)
Title: Synthesis of crac channel inhibitors
Inventor: STAUDERMAN KENNETH A
IPC: A61K31/485
Filed: 2020-05-05
Abstract: A convergent synthetic method for the production of CRAC channel inhibitors is described herein. The synthetic method provides a method for producing highly pure CRAC channel inhibitors for clinical testing.
Patent CA-3140278-A1 (CA)
Inventor: BEE MARKUS
IPC: B26D7/18
Filed: 2020-05-26
Abstract: La présente invention concerne un ensemble d'outils (30) pour fabriquer des timbres adhésifs (84), par traitement de bande stratifiée (80). L'ensemble d'outils (30) comprend un outil de coupe (51) ayant une face de coupe (52) se trouvant dans un plan de coupe, et un outil de gaufrage ayant une face de pression (37) se trouvant dans un plan de pression, le plan de coupe et le plan de pression étant parallèles. L'outil de gaufrage (31) est conçu pour presser une forme de zone de bord (104) du timbre adhésif (84) à fabriquer, et l'outil de coupe (51) est conçu pour découper le timbre adhésif (84) à fabriquer en découpant dans la zone de bord (104) ou à l'extérieur de la zone de bord (104). De plus, la présente invention concerne un procédé de fabrication de timbres adhésifs. Le procédé comprend essentiellement une étape d'alimentation, une étape de pression et une étape de découpe. Enfin, une couche adhésive (100) comprend une couche de doublage (83) et une couche de matrice adhésive. La couche de doublage (83) présente une taille supérieure à la couche de matrice adhésive.
Patent CA-3141373-A1 (CA)
Title: Portable dehydriding apparatus and method of using same
Inventor: HANLON SEAN
IPC: C01G25/00
Filed: 2020-05-22
Abstract: A method of removing hydrogen interstitially dissolved within an object can include: positioning a sorption pad having a contact surface and comprising a sorptive material; urging the contact surface into metallurgical contact with the first target surface while at a treatment temperature that is greater than about 200 degrees Celsius; c) maintaining the metallurgical contact for a treatment period during which the hydrogen migrates from the target object to the sorptive material; and at the conclusion of the treatment period, separating the contact surface from the first target surface and moving the sorption pad and any hydrogen sequestered therein away from the object.
Patent CA-3141966-A1 (CA)
Title: Outdoor mobile office pod
Inventor: DUBE-SEXTON SIMON
IPC: B65D88/10
Filed: 2021-12-10
Abstract: There is provided an outdoor mobile office pod, which is affordable and mobile to combine working with travelling, off-grid living and other adventurous work setups.  The pod allows remote workers to increase their vitamin D intake and to breath fresh air while working in a comfortable environment sheltered from inconsistent weather in order to have a positive impact on mental health. In one aspect there is provided a mobile office pod with one or more walls made from impact resistant acrylic. At least four wheels are configured to be attached to an external side of the base underneath the pod and at least one levelling jack is configured to be attached to an external side of the base underneath the pod.
Patent CA-3142129-A1 (CA)
Title: Sod harvesting systems and related methods
Inventor: BROUWER GERARDUS J
IPC: A01G20/15
Filed: 2020-06-16
Abstract: A harvesting system for harvesting sod includes: (a) a harvester frame; (b) a cutting assembly mounted to the harvester frame for cutting the sod into slabs, each slab having a cut-off length; (c) a conveyor assembly supported by the harvester frame for transporting the slabs away from the cutting assembly 5 toward a measuring location; and (d) a control system operable to: (i) determine a length difference between a measured length for at least one slab at the measuring location and a target length, and (ii) adjust the cut-off length for subsequent slabs to compensate for the length difference.
Patent CA-3142309-A1 (CA)
Inventor: PETERS FRANK
IPC: B62D11/18
Filed: 2019-11-08
Abstract: Un véhicule d'entretien de pelouse assis comprend un châssis sur lequel au moins deux roues motrices peuvent être attachées, un moteur en raccord fonctionnel avec le châssis et les roues et alimentant les roues, un mécanisme de direction possédant deux leviers de direction et un assemblage de travail. Les leviers sont chacun en raccord fonctionnel à l'une des roues motrices pour faciliter le virage du véhicule en fonction du contrôle de la vitesse d'entraînement de chaque roue selon le positionnement de chaque levier. L'assemblage de travail est en raccord fonctionnel au moteur et exécute une fonction de travail en réponse à l'alimentation du moteur. Chaque levier comprend une partie de préhension. Au moins un des leviers est en raccord fonctionnel avec un module de commande (installé de façon externe sur le levier) à proximité, mais séparément de la partie de préhension. Le module de commande comprend un opérateur de commande configuré pour contrôler l'opération du moteur ou de l'assemblage de travail.
Patent CA-3142453-A1 (CA)
Title: Vented utility meter enclosure
Inventor: NELSON KIRBY KIMBLE III
IPC: G01D11/24
Filed: 2020-07-31
Abstract: An enclosure for a utility metering device is configured to reduce internal air temperatures. In an example, the utility metering device has a solar shield and/or filtered ventilation air passage(s). In the example, an enclosure is attached to a base. Opening(s) may be defined in the enclosure, to allow air to remove heat from the metering device by convection. The openings may be covered with filters, to prevent the entry of water, dust, insects, etc. A solar shield may cover at least an upper surface of the enclosure. An air pocket may be defined between the solar shield and at least the upper surface of the enclosure. Air from within the enclosure may be ventilated into the air pocket, and air from within the air pocket may be ventilated into the atmosphere. The ventilation removes heat from within the enclosure, while the solar shield rejects addition of heat energy.
Patent CA-3143188-A1 (CA)
Title: Hdac3 catalytic inhibitor development and uses thereof
Inventor: LI DEYAO
IPC: A61K31/497
Filed: 2020-06-12
Abstract: Provided herein are compounds of Formula I depicted below, pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat diseases or disorders associated with HDAC3 activity.