baber/WOPTO huggingface dataset:
Patent IE-890265-L (IE)
Title: Quinoline, quinazoline and cinnoline derivatives
IPC: C07D215/42
Filed: 1989-01-27
Abstract: Compounds of the formula (1): <CHEM>  wherein:  R<1> to R<4> are independently H, halo, (C1-C4) alkyl, branched (C3-C4) alkyl, halo (C1-C4) alkyl, (C1-C4) alkoxy, NO2, or NH2, at least two of R<1> to R<4> being H, or one of R<2> to R<4> is -NR<7>-Y-Ar or O-Y-Ar and the rest of R<1> to R<4> are H;  W is N, or CR<5>;  R<5> is H, CH3, Cl, O-Y-Ar, or -NR<7>-Y-Ar;  R<6> is H, CH3, Cl or Br;  A is -O-Alk or -X-Y-Ar; Alk is a C2-C18 saturated or unsaturated hydrocarbon chain, straight chain or branched, optionally substituted with halo, halo (C1-C4) alkoxy, (C3-C8) cycloalkyl, hydroxy, or acetyl; X is O, NR<7>, or CR<8>R<9>, provided that if one of R<2> to R<5> is NR<7>-Y-Ar or O-Y-Ar, then X-Y-Ar is an identical group;  R<7> is H, (C1-C4) alkyl, or acetyl; R<8> and R<9> are independently H, (C1-C4) alkyl, (C1-C4) acyl, halo, or OH, or R<8> and R<9> combine to form a saturated or unsaturated carbocyclic ring comprising three to seven carbon atoms; Y is an alkylene chain 2 to 8 carbon atoms long, optionally including an O, S, SO, SO2, or NR<7> group or a saturated or unsaturated carbocyclic ring comprising three to seven carbon atoms, or substituted with (C1-C3) alkyl, (C2-C4) alkenyl, phenyl, (C3-C8) cycloalkyl, hydroxy, halo, or (C1-C4) acyl; and  Ar is  1,3-benzodioxolyl  fluorenyl,  pyridyl,  imidazolyl,  indolyl,  thienyl, optionally substituted with CH3 or Cl,  thiazolyl,  cyclopentyl,  1-methylcyclopentyl,  cyclohexenyl (hexahydrophenyl),  cyclohexyl (tetrahydrophenyl),  naphthyl,  dihydronaphthyl,  tetrahydronaphthyl,  decahydronaphthyl, or  a group of the formula (2): <CHEM>  where R<1><0> to R<1><4> are independently H, halo, I, (C1-C10) alkyl, branched (C3-C6) alkyl, halo (C1-C4) alkyl, (C1-C4) alkoxy, halo (C1-C4) alkoxy, phenoxy, substituted phenoxy, phenylthio, substituted phenylthio, phenyl, substituted phenyl, NO2, NH2, acetoxy, OH, CN, or SiR<1><5>R<1><6>R<1><7>, OSir<1><5>, R<1><6>, R<1><7>, where R<1><5>, R<1><6>, and R<1><7> are independently (C1-C4) alkyl or (C3-C4) branched alkyl, provided that unless each of R<1><0> to R<1><4> is F, CH3, or H, then at least two of R<1><0> to R<1><4> are H;  or an acid addition salt of a compound of formula (1)  or an N-oxide of a compound of formula (1) when W is CR<5> are fungicides, insecticides, and miticides.
Patent IE-41350-L (IE)
Title: Substituted phenoxypropanolamines
IPC: A01N33/02
Filed: 1975-02-13
Abstract: This invention relates to novel compounds of the general formula <IMAGE> Representative compounds within the scope of the invention are <IMAGE> <IMAGE> The compounds are disclosed as being useful for treating symptoms and signs of cardiac failure by stimulating the beta -receptors of the heart. Methods of treatment using these compounds are discussed.
[US4244969A]
Patent IE-45408-L (IE)
Title: Protsaglandin analogues
IPC: A61K31/70
Filed: 1977-03-10
Abstract: The present invention relates to prostaglandin analogues of the general formula: <IMAGE> [wherein X represents cis or trans-vinylene or ethylene, Z represents <IMAGE> R1 represents a hydrogen atom or a straight- or branched-chain alkyl group containing from 1 to 12 carbon atoms, R2 represents a hydrogen atom or a methyl group, R3 represents a straight- or branched-chain alkylene group containing from 1 to 7 carbon atoms and R4 represents a cycloalkyl group containing from 5 to 7 carbon atoms, a grouping of the formula: <IMAGE> (wherein R5 and R6, which may be the same or different, each represent a hydrogen atom or halogen atom, a trifluoromethyl group or a straight- or branched-chain alkyl group containing from 1 to 4 carbon atoms), or a grouping of the formula: <IMAGE> (wherein R5 and R6 are as hereinbefore defined), or R3 and R4 together represent a straight- or branched-chain alkyl group containing from 1 to 10 carbon atoms, and (1) the double bond between C3-C4 is trans or cis, or trans and cis, when X is cis-vinylene or ethylene, and (2) the double bond between C3-C4 is trans, when X is trans-vinylene, and the double bond between C13-C14 is trans] and cyclodextrin clathrates of such acids and esters, and when R1 represents a hydrogen atom, non-toxic salts thereof, which exhibit characteristic prostaglandin-like activities.
[US4145555A]
Patent IE-32354-L (IE)
Title: Propanolamine derivatives
IPC: C07C67/00
Filed: 1968-05-13
Abstract: 1,227,383. Propanolamine derivatives. BOEHRINGER INGLEHEIM G.m.b.H. 20 May, 1968 [18 May, 1967; 1 June, 1967], No. 23978/68. Heading C2C. [Also in Division A5] Racemic and optically active compounds of the general formula (R = C 1-4 alkyl, R 1 = ethynyl and R2,3 = H or C 1-4 alkyl or alkoxy) and their salts are prepared by (a) reacting a compound of the formula (Z = oxiranyl or 2-halo-1.hydroxyethyl) with RNH 2 , (b) removing the protecting group G from a compound of the formula or (c) hydrolysing a compound of the formula or (R 4 , 5 = H, alkyl, aralkyl or aryl), optionally followed in each case by resolution and/or salt formation.
[GB1227383A]
Patent IE-900587-L (IE)
Title: Protein anti-cancer agent
IPC: C12N/
Filed: 1990-02-16
Abstract: We have modified PE40 toxin by removing at least two of its four cysteine amino acid residues and have formed hybrid molecules containing modified PE40 linked to a cell recognition protein that can be an antibody, a growth factor, a hormone, a lymphokine, or another polypeptide cell recognition protein for which a specific cellular receptor exists whereby the modified PE40 toxin is directed to cell types having receptors for the cell recognition protein linked to the modified PE40.
Patent IE-780759-L (IE)
Title: Ergot alkaloids.
IPC: C12P1/00
Filed: 1978-04-18
Abstract: Ergot alkaloids having interesting pharmacological activities, for instance in the therapy of migraine or hypertension. Such compounds are obtained in a fermentative process using mutant strains of Claviceps purpurea eventually hydrogenating the products thus obtained.
[US4230854A]
Patent IE-820815-L (IE)
Title: Anti-cancer drug.
IPC: A61K39/395
Filed: 1982-04-06
Abstract: The present invention relates to drugs useful in particular for the treatment of melanomas, characterized in that they contain an active substance which is a molecule in which the chain A of ricin is associated, by a covalent bond of disulfide type, with a human antimelanoma antibody.
[US4414148A]
Patent IE-840822-L (IE)
Title: Triaxially-braided fabric prosthesis.
IPC: A61F2/08
Filed: 1984-04-03
Abstract: A novel prosthesis for use in repairing or replacing soft tissue is disclosed, which comprises a triaxially-braided fabric element having interwoven first, second and third sets of fibers, with the fibers of the second and third sets being oriented at substantially the same acute braiding angle with respect to the fibers of the first set. An elongated ligament prosthesis exhibiting the desired properties of high strength and high elasticity may be prepared by selecting high elasticity fibers for the first set, orienting said first set of fibers in the longitudinal direction of the prosthesis and selecting fibers having high yield strength and high Young's modulus for the second and third sets. A tubular prosthesis in which high elasticity fibers are oriented in the longitudinal direction is highly suitable for use as a vascular prosthesis. A prosthesis of the invention may also be manufactured in the form of a prosthetic heart valve leaflet.
Patent IE-39751-L (IE)
Title: Process for the production of mannitol and sorbitol
IPC: C07C29/76
Filed: 1974-04-24
Abstract: A method for separating mannitol and sorbitol from a solution containing mannitol and sorbitol, including the step of chromatographic fractionation to provide an aqueous solution containing a high level mannitol and an aqueous solution containing a high level of sorbitol. When desired, aqueous solutions of pure mannitol (free from sorbitol and unhydrogenated sugar) and pure sorbitol (free from mannitol and unhydrogenated sugar) may be obtained.
[US3864406A]
Patent IE-34421-L (IE)
Title: Seam connection
IPC: B21D51/20
Filed: 1970-07-24
Abstract: 1325706 Seaming KONINKLIJKE EMBALLAGE INDUSTRIE VAN LEER NV 23 July 1970 [1 Aug 1969 30 June 1970] 35769/70 Heading B3J A sheet metal closure 1 is seamed to a sheet metal container 2 by providing the container with a flange 19, Fig. 8, which, in axial crosssection of the container, curves outwardly over substantially its full width, forming a U- shaped channel 13 in the closure flange 14 and rolling the flanges together with a roller having a groove matching the seam to be rolled. Sealing material (15) may be applied to the closure 1 before or after, Figs. 6 or 7 (not shown) a preliminary channel 13 is formed by a roller (16). The material may be polyurethane or a rubber-based compound applied by spraying, or a loose or bonded ring of rubber, &c. may be used, the material being brought into a final condition if necessary by drying or vulcanizing.
[GB1325706A]
Patent FI-851529-L (FI)
Inventor: ENGELS JOACHIM
IPC: C12P19/34
Filed: 1985-04-17
Abstract: Partial sequences of human- gamma -interferon, comprising aminoacid sequences 5 to 127, 1 to 127 and 5 to 146, having biological activity. These partial sequences can be obtained by a genetic engineering process, for which purpose the appropriate DNA sequences are chemically synthesized. The DNA sequences are incorporated in hybrid plasmids, and the latter are introduced into host organisms and their expression is induced there. The biologically active polypeptides are suitable, as is human- gamma -interferon, for medicaments.
Patent IE-881116-L (IE)
Title: Disinfecting compositions and methods therefor
IPC: A61K8/20
Filed: 1988-04-13
Abstract: The present invention relates to compositions that are effective oral disinfectants which do not have the strong unpleasant taste of chlorine and are useful in reducing plaque. The invention also concerns processes for making these compositions.
Patent IE-821315-L (IE)
Title: PREPARATION OF 5,6,7,7a-TETRAHYDRO-4H-THIENO-£3,2-c|¹PYRIDIN-2-ONES
IPC: C07D495/04
Filed: 1982-06-01
Abstract: The present invention provides a process for the preparation of 5,6,7,7a-tetrahydro-4H-thieno[3,2-c]-pyridin-2-ones of the general formula: <IMAGE> (I) in which R is a hydrogen atom or a phenyl radical optionally substituted by at least one halogen atom, lower alkyl radical, lower alkoxy radical, nitro group, carboxyl group or alkoxycarbonyl radical, R' is a hydrogen atom or lower alkyl radical and n is 0 or a number of from 1 to 4, wherein a compound of the general formula: <IMAGE> (V) in which R, R' and n have the same meanings as above, is reacted with formaldehyde to give a compound of the general formula: <IMAGE> (VI) in which R, R' and n have the same meanings as above, whereafter this compound is treated with dry hydrogen chloride to give the desired compound of general formula (I). The compounds are useful as anti-thrombotic agents.
[US4458074A]
Patent IE-811668-L (IE)
Title: Multiple-array induction logging tool
IPC: G01V3/10
Filed: 1981-07-23
Abstract: A sonde for induction logging of boreholes comprising a transmitter-receiver coil array having et least two groups of coils that are time or frequency multiplexed. The response functions of the groups overlap vertically in such a manner that a lower portion of one group overlaps an upper portion of another group. The response of the sonde is obtained by combining the responses detected in several receiver groups at differents depths.
[EP0045243A2]
Patent IE-38386-L (IE)
Title: Shampoo composition
IPC: C11D1/88
Filed: 1973-10-17
Abstract: Shampoo compsn contg sulphated or sulphated ethoxylated amine/amide/alkanolamide of fatty acid, and cationic conditioning agent
[CH603158A5]
Patent IE-832058-L (IE)
Title: 1,4-dihydropyridine derivatives
IPC: C07D407/12
Filed: 1983-09-01
Abstract: 1,4-Dihydropyridine derivatives of the formula:-and their pharmaceutically acceptable acid addition salts; whereR is aryl or heteroaryl;R<sup>1</sup> and R<sup>2</sup> are each independently C<sub>1</sub>-C<sub>4</sub> alkyl or 2-methoxyethyl;Y is -(CH<sub>2</sub>)<sub>2</sub>-, -(CH<sub>2</sub>)<sub>3</sub>-, -CH<sub>2</sub>CH(CH<sub>3</sub>)- or -CH<sub>2</sub>C(CH<sub>3</sub>)<sub>2</sub>-;R<sup>3</sup> is hydrogen or a group selected from:-where R<sup>4</sup> is H, C<sub>1</sub>-C<sub>4</sub> alkyl, C<sub>3</sub>-C<sub>6</sub> cycloalkyl, -COO(C<sub>1</sub>-C<sub>4</sub> alkyl), -CH<sub>2</sub>COO(C<sub>1</sub>-C<sub>4</sub> alkyl), aryl, -S0<sub>2</sub>.aryl, or heteroaryl, and X is 0 or S;where R<sup>5</sup> is 1-pyrrolidinyl, -NH<sub>2</sub>, -NH(C<sub>1</sub>-C<sub>4</sub> alkyl), -N/C<sub>1</sub>-C<sub>4</sub> alkyl)<sub>2</sub>, or -NH(CH<sub>2</sub>)<sub>2</sub>N(C<sub>1</sub>-C<sub>4</sub> alkyl)<sub>2</sub>;where R<sup>6</sup> is C<sub>1</sub>-C<sub>4</sub> alkyl or aryl;where R<sup>7</sup> is -CONH(C<sub>1</sub>-C<sub>4</sub> alkyl) or -COO(C<sub>1</sub>-C<sub>4</sub> alkyl);where R<sup>8</sup> is -CN, -SO<sub>2</sub>(C<sub>1</sub>-C<sub>4</sub> alkyl) or -SO<sub>2</sub> aryl;(h) -CH<sub>2</sub>CO.R<sup>9</sup> where R<sup>9</sup> is -NH<sub>2</sub>, -NH(C<sub>1</sub>-C<sub>4</sub> alkyl), -NH.aryl or C<sub>1</sub>-C<sub>4</sub> alkoxy;(i) -SO<sub>2</sub>.R<sup>10</sup> where R<sup>10</sup> is -NH<sub>2</sub>, -N(C<sub>1</sub>-C<sub>4</sub> alkyl)<sub>2</sub> or C<sub>1</sub>-C<sub>4</sub> alkyl; and(j) -CO.R" where R" is H, halomethyl, -COO(C<sub>1</sub>-C<sub>4</sub> alkyl), -CH<sub>2</sub>O(C<sub>1</sub>-C<sub>4</sub> alkyl), -CH<sub>2</sub>CO(C<sub>1</sub>-C<sub>4</sub> alkyl), C<sub>1</sub>-C<sub>4</sub> alkyl, C<sub>1</sub>-C<sub>4</sub> alkoxy, aryl, heteroaryl, morpholino or 5-oxo-pyrrolidin-2-yl.The compounds have utility as anti-ischaemic and antihypertensive agents.
Patent IE-872128-L (IE)
Title: Preventing the copying of a video program
IPC: H04N5/76
Filed: 1987-08-10
Abstract: A video signal is modified so that a television receiver will still provide a normal color picture but which a video tape recorder will detect and prohibit its being recorded. A plurality of ordered pairs of pseudo-sync and positive pulses are added to the video signal vertical blanking interval following the normal sync pulse. A disabling circuit (22) in a video tape recorder (10) detects the modified signal. This detection may be by comparing the voltage differential between the pseudo-sync pulse tip and the positive pulse relative to the normal voltage differential between the sync pulse tip and the back porch of the blanking interval. Alternatively, the modified signal can be detected by identifying the pulse frequency of the signal in the blanking interval. A high frequency is indicative of the presence of the modified signal. A control signal (26) is produced by the disabling circuit (22) when the modified signal is present, and this disables a recording device (20). If no modified signal is detected, the recording device is enabled.
Patent IE-872409-L (IE)
Title: Pyrrolidine derivatives
IPC: C07D521/00
Filed: 1987-09-09
Abstract: The invention relates to a group of new phenyl, pyrrolidin-2-yl substituted 5-ring heterocyclic compounds of the formula <CHEM> wherein A is an unsaturated heterocylic 5-ring having at least one nitrogen or oxygen atom in the ring, with the proviso that the phenyl substituent is in a meta-position with respect to the 2-pyrrolidinyl substituent. The compounds have interesting pharmacological, notably antipsychotic properties.
Patent IE-782420-L (IE)
Title: A-40104 antibiotics.
IPC: A61P31/04
Filed: 1978-12-07
Abstract: {PG,1 A-40104 antibiotic complex, comprising active factors A, B, C, and D, produced by submerged aerobic fermentation of {i Clitopilus pseudo-pinsitus. {l Individual factors, A, B, and C have been isolated. A-40104 factor C is the known antibiotic pleuromutilin. A-40104 factors A and B are novel antibiotics related to pleuromutilin. A-40104 factor A, the major new factor, is the D-xylose acetal derivative of pleuromutilin. A-40104 factors A and B, their 19,20-dihydro derivatives and the per(C{HD 2{L {14 C{HD 6{L )alkanoyl derivatives of factors A and B and of their 19,20-dihydro derivatives are active against gram-positive and gram-negative bacteria, anaerobic bacteria, and Mycoplasma.
[US4129721A]
Patent NO-793151-L (NO)
Inventor: BELLASIO ELVIO
IPC: A61K31/535
Filed: 1979-10-01
Abstract: New N-pyrrolyl-3-pyridazine-amines having a further aminic substituent in the 6 position of the formula (I), <CHEM> wherein R, R1, R2 and R3 are hydrogen or lower alkyl, R4 is e.g. hydrogen or lower alkyl, R5 and R6 are e.g. lower alkyl or taken together with the adjacent nitrogen atom represent a saturated 5 - 6 membered heterocyclic ring which may contain a further heteroatom, R7 and R8 represent hydrogen or, taken together, a 1,3-butadienylene radical forming a benzo system fused with the pyridazine ring, for example N-2,5-dimethyl-1H-pyrrol-1-yl)- 6-morpholino-3-pyridazineamine or N-(2,5-dimethyl-1H-pyrrol- 1-yl)-4-(4-hydroxypiperidino)-1-phthalazineamine, and their pharmaceutically acceptable salts are made e.g. by contacting a hydrazino derivate of the formula (II), wherein the substituents have the same meaning as above or an acid addition salt thereof with a dicarbonyl compound of the formula (III), wherein the substituents have the same meaning as above, or a functional derivative thereof in the presence of an acid catalyst at a temperature between 15 DEG C and 120 DEG C. The new compounds can be used as antihypertensive agents.
Patent NO-810847-L (NO)
Title: Laasbart, vribart skistativ.
Inventor: KOCH ERLING
IPC: B60R/
Filed: 1981-03-12
Abstract: Låsbart skistativ for bil der klemmeanordningene er festet med glide- eller rullelager til bærebøylen, og der dekseldelen på stativet, som inneholder låsen og som dekker festemekanismen, kan hektes fast til en av flere alternative festebraketter, slik at klemmeanordningene, som er utformet mest mulig strømlinjet, kan festes i forskjellige vinkler til biltaket, ettersom formålet er å holde på ski, skape nøddrift, eller bare å yte minst mulig luftmotstand. ;\
Patent NO-814195-L (NO)
Inventor: BENNWIK PERCY
IPC: A61J1/00
Filed: 1981-12-09
Abstract: The invention relates to a package protecting its contents from the influence of light, microbial contamination and gas transport in either direction but which makes possible a visual control of the contents before the package is used. 
<??>According to the invention, the package is made of a light-proof outer bag (1) and a light permeable inner bag (3) arranged inside the outer bag. The outer bag (1) and the inner bag (3) are each sealed at one of their ends (2, 4) and are bonded around their periphery (6) close to their other end, and the two bags extend over this bond and are then commonly joined and sealed. By opening one of the end seals in the outer bag (1), the inner bag (3) can be turned out of the outer bag, and the contents (5) of the package can be observed visually through the inner bag. 
<??>The package of the invention is especially suitable for storage of preparations for parenteral administration and especially infusion solutions intended to be given intravenously.
Patent NO-831602-L (NO)
Inventor: GONZALEZ BUENAVENTURA SABATER
IPC: A47C7/46
Filed: 1983-05-05
Abstract: An arrangement for the distribution of pressurised fluid to areas of a seat unit having a backrest comprising a first fluid-containing chamber (3) adaptable to the seat area (4) of the seat unit (2) so as to be adapted to receive, at least in part, the user's weight; one or more inflatable chambers (6,7) adaptable to the seat unit backrest; and lines (8, 9) communicating between the first chamber (3) and each said backrest (5) chamber (6, 7). Each line (8, 9) has inserted therein a normally closed valve means (50) provided with an opening means with opening controls (81,95) positioned in the seat unit such as to be accessible to the user. The invention also relates to an embodiment of said valve.
Patent NO-833071-L (NO)
Inventor: STIEFEL FRANK J
IPC: C07D295/12
Filed: 1983-08-26
Abstract: A novel, efficient, economical procedure for the synthesis of ethers of n-propanoldiamine having the formula:   <IMAGE>   wherein R is a straight or branched chain lower alkyl group or an aralkyl group, Ar is an aromatic group, Ar1 is an aromatic or heterocyclic group, A is a tertiary aliphatic, cycloaliphatic or heterocyclic amino group and addition salts thereof with pharmacologically acceptable acids.
Patent NO-841375-L (NO)
Inventor: DENOJEAN JACQUES
IPC: D06N3/00
Filed: 1984-04-06
Abstract: 1. Decorated coated textile structure comprising a flexible textile support, a coloured decorative pattern and a transparent film covering the support and the decorative pattern consists of a coloured flocking adhesive and a textile flock which overlaps the textile support on the face that is not covered by the transparent film.
Patent NO-860520-L (NO)
Inventor: HENRIKSEN NOROLF
IPC: B01D19/00
Filed: 1986-02-13
Abstract: Method and means for treating of and mass transfer in liquid/gas mixtures, especially removal of oxygen from seawater to be injected into deep structures to increase the production of underground hydrocarbon resources. The oxygen removal is performed by means of an inert stripping gas which is purified and regenerated before it is recirculated. 
<??>Liquid and gas is pumped in turbulent concurrent flow with the inert gas through one or more tubelike zones (2) to one or more separation zones (6) where gas and liquid are separated. The liquid is led to the next treatment stage, while the stripping gas is returned to the prior treatment stage. The liquid flow and the gas flow are pumped and controlled independently of each other, to allow optimal treatment conditions and correct amount of transported liquid to be obtained.
Patent NO-870011-L (NO)
Title: Fjernstyrt maskin for rensing, inspeksjon og vedlikehold av undervannskonstruksjoner.
Inventor: FIELDER NICHOLAS ALBERT WILLIA
IPC: B63B/
Filed: 1987-01-02
Abstract: Apparat for undervanns vedlikehold, omfattende en delvis ringformet hoveddel (20) med flere svingearraer (21) som strekker seg utover på. hver side av hoveddelen og er dreibart montert på denne for å kunne bevege seg radialt innover. Apparatet omfatter videre støtteelementer (22) som er festet til svingearmene og innrettet for anlegg mot et hovedsakelig sylindrisk konstruksjonselement (18) som det skal utføres arbeide på og som delvis omsluttes av hoveddelen (20). Et rensehode (27) er festet til hoveddelen (20) og innrettet for radial innoverrettet forskyving, og apparatet omfatter endelig drivorganer for å bevirke aksial bevegelse av hoveddelen (20) på konstruksjons-elementet (18) .
Patent NO-891895-L (NO)
Inventor: JAKUBICKI GARY J
IPC: C11D3/37
Filed: 1989-05-09
Abstract: A non-scratching household cleaning composition containing as a major ingredient poly[alpha-methyl-styrene-styrene-acrylonitrile] commercially available as "BLENDEX 586". This ingredient is blended with a conventional surfactant and builder. The system can also contain a solvent or bleach system. The BLENDEX 586 component is present as finely divided particles having a size range of about 44-to-420 microns.