baber/WOPTO huggingface dataset:
Patent NZ-724378-A (NZ)
Title: Muscarinic receptor agonists
Inventor: BROWN GILES ALBERT
IPC: C07D519/00
Filed: 2015-03-19
Abstract: This invention relates to compounds that are agonists of the muscarinic M1 receptor and which are useful in the treatment of muscarinic M1 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formula (1a) where m, p, q, W, Z, Y, X1, X2, R1, R2 R3 and R4 are as defined herein.
Patent NZ-727755-A (NZ)
Title: Mapc therapeutics without adjunctive immunosuppressive treatment
Inventor: MAYS ROBERT W
IPC: A61P9/10
Filed: 2007-01-23
Abstract: Disclosed is a use of multipotent cells in the manufacture of a medicament for treating an injury, dysfunction, disorder, and/or disease in a subject likely to suffer, suffering, or who has suffered an injury, dysfunction, disorder or disease, provided that the injury is not a brain injury wherein the cells are derived from bone marrow, isolated, expanded, non-embryonic, non-germ cells that express telomerase, can differentiate into at least two of the endodermal, ectodermal, and mesodermal embryonic lineages, have undergone at least 10-40 cell doublings in culture and are allogeneic or xenogeneic, wherein said medicament does not comprise an immunosuppressant and is to be administered without an immunosuppressive treatment.
Patent NZ-730571-A (NZ)
Title: Pharmaceutical compositions having improved storage stability
Inventor: MAGALI B HICKEY
IPC: A61K31/4704
Filed: 2013-09-19
Abstract: Disclosed are pharmaceutical compositions and method of their preparation that provides long-term stability of a hydrolytically labile antipsychotic agent (e.g., aripiprazole or olanzapine). The method of preparation comprises the addition of: a) a non-ionic water insoluble and/or immiscible ester cosurfactant (e.g., a sorbitan ester such as sorbitan laurate); and (b) a water miscible and/or soluble non-ionic surfactant (a polyoxyethylene derivative of a sorbitan ester such as polysorbate 20).
Patent NZ-733217-A (NZ)
Title: Outlet connection assembly and method of making the same
Inventor: HUBY RONALD JAMES
IPC: A61M16/16
Filed: 2014-06-24
Abstract: An outlet connector assembly 4106 for a device to deliver continuous positive airway pressure to a patient for treatment of sleep disordered breathing. The assembly 4106 comprises a body having a tube connection region 4104 and an outlet connection region 4114, a cap 4124 structured to attach to the body such that the cap 4124 and the body at least partially define an airflow path between the tube connection region 4104 and the outlet connection region 4114. There is an electrical contact assembly 4112 molded to the body and configured to form an electrical connection between the tube connection region 4104 and the outlet connection region 4114.
Patent NZ-751830-A (NZ)
Title: Combination therapy comprising a b-raf inhibitor and a second inhibitor
Inventor: CAPONIGRO GIORDANO
IPC: A61P35/00
Filed: 2014-03-19
Abstract: The application relates to a pharmaceutical combination consisting essentially of a B-Raf inhibitor of Formula (I) or a pharmaceutically acceptable salt thereof, and a second inhibitor which is a PI3 kinase inhibitor selected from 5-(2,6-di-morpholin-4-yl-pyrimidin-4-yl)-4-trifluoromethyl-pyridin-2-ylamine (Compound F), or a pharmaceutically acceptable salt thereof and (S)-pyrrolidine-1,2-dicarboxylic acid 2-amide 1-({ 4-methyl-5-[2-(2,2,2-trifluoro-1,1-dimethyl-ethyl)-pyridin-4-yl]-thiazol-2-yl} -amide) (Compound X), or a pharmaceutically acceptable salt thereof, wherein the combination is adapted for administration simultaneously or sequentially.
Patent NZ-752969-A (NZ)
Title: Tobacco blend
Inventor: SUTTON JOSEPH
IPC: A24F40/42
Filed: 2017-11-08
Abstract: Compositions for use in a device for generating an inhalable medium are described. Tobacco compositions used in e-cigarettes, which vaporise a liquid to provide an inhalable vapour, and tobacco heating devices, which release compounds by heating, but not burning, the material are not optimal for use in hybrid e-cigarette / tobacco heating devices. The composition of the present invention is optimised for use in hybrid electronic smoking devices for generating a desired delivery or flavour profile. The claimed compositions include a blend of both treat and untreated tobacco, that is - flue-cured and/or sun-cured tobacco that has not been subjected to any further treatment comprising a Maillard reaction, and flue-cured and/or sun-cured tobacco that has been subjected to a further treatment comprising a Maillard reaction.
Patent NZ-763926-A (NZ)
Title: Procedure for the production of a multiplier and modulator additive of the ruminal microbiota
Inventor: PATERNÓ MARCELO ALEJANDRO
IPC: A23K10/00
Filed: 2018-09-17
Abstract: The present invention discloses a multiplier and modulator additive of the ruminal microbiota created from exogenous multienzyme compounds, integrating processes and devices for cultivating and harvesting biomass of selected fungal species, assembling active components of fungal origin and by mixing supplies according to specifications, forming thus a multiplier and modulator additive of the ruminal microbiota suitable for its application (as part of food or via distribution devices as a nutritional supplement) in the ruminant animal feed industry.
Patent PT-101013-A (PT)
Inventor: HARDY FREDERICK EDWARD
IPC: C11D1/02
Filed: 1992-10-28
Abstract: A detergent composition comprises (a) one or more glyceryl ethers of a C12-C18 alkyl or alkenyl primary or secondary alcohol, at least 50 mole percent of the glyceryl ether being diglyceryl ether and not more than 25 mole percent of the glyceryl being monoglyceryl ether, and (b) an anionic detersive surfactant. The compositions, which may be in granular or liquid form, may also contain other conventional ingredients, e.g. other detersive surfactants, detergency building compounds, enzymes and bleaches.
Patent PT-102660-A (PT)
Title: Polydentate quelling agents of 3-hydroxy-4-pyridinone type involve two or more bidentated units of 3-hydroxy-4-pyridinone interconnected by simple molecular systems
Inventor: SEABRA MARIA AMELIA LOUREIRO S
IPC: C07D213/89
Filed: 2001-08-21
Abstract: Polydentate quelling agents of 3-hydroxy-4-pyridine type involve two or more bidentated units of 3-hydroxy-4-pyridinone interconnected by simple molecular systems (monomeric) or polymeric. From the adequate selection of molecular supports and of substitutive groups in the quelling units, and from spacer groups isolated between those units, an amalgam of new compounds is established.
Patent PT-103841-A (PT)
Title: Sistema de construtivo para fachadas ventiladas
Inventor: CUNHA MARCIO MANUEL FERREIRA DA
IPC: E04F13/08
Filed: 2007-09-26
Abstract: SISTEMA CONSTRUTIVO PARA FACHADAS VENTILADAS CARACTERIZADO PELA POSSIBILIDADE DE APOIAR VÁRIOS TIPOS DE MATERIAIS DE REVESTIMENTO, COM FIXAÇÃO CONTÍNUA OCULTA OU VISÍVEL, QUE PERMITE VENCER VÃOS ENTRE APOIOS ATÉ 2,LOM PARA ESPAÇAMENTOS ENTRE PERFIS DE 1,20M, ESTANDO ISENTO DE QUALQUER TIPO DE PERFURAÇÕES PARA APERTO DE PARAFUSOS OU REBITES, PERMITINDO UMA MAIOR PRECISÃO EM AFINAÇÕES. 	O	SISTEMA DE FIXAÇÃO É COMPOSTO POR UMA ESTRUTURA DE SUPORTE CONSTITUIDO POR PERFIS VERTICAIS EM ALUMÍNIO (1), FIXADOS À ESTRUTURA DE BETÃO ARMADO ATRAVÉS DE CANTONEIRAS EM ALUMÍNIO (5> E CHUMBADOUROS COM BUCHAS MECÂNICAS EM AÇO (7) 	OS PERFIS VERTÍCAIS (1) E AS ANCORAGENS DE ALUMÍNIO (5) ESTÃO CONECTADOS ATRAVÉS DE PARAFUSOS EM AÇO INOX M5 (9) COM GUIAS DE DILATAÇÃO (8) NOS APOIOS SIMPLES E PARAFUSOS M6 (6) DO MESMO MATERIAL NOS APOIOS DUPLOS. 	AS PLACAS DE REVESTIMENTO (4) ENCOSTAM NOS PERFIS DE ENCOSTO EM EPDM (2) ADICIONADOS NOS PERFIS VERTICAIS EM ALUMÍNIO (1), FICANDO APOIADAS NOS CLIPS DE SUPORTE (3) EM AÇO ÍNOX QUE SE AUTO-SUPORTAM NOS PERFIS VERTICAIS (1) POR PRESSÃO. A ORDEM DAS TRABALHOS É A SEGUINTE: -PREPARAÇÃO DOS PROJECTOS E ESTEREOTOMIA DA FACHADA; - MARCAÇÃO E FURAÇÃO DA TRAMA ESTRUTURAL; - APERTO DAS CANTONEIRAS (5) NAS BUCHAS MECÂNICAS (7); APLICAÇÃO DOS PERFIS VERTICAIS EM ALUMÍNIO (1) COM OS PERFIS DE ENCOSTO EM EPDM (2); - APLICAÇÃO DO ISOLAMENTO TÉRMICO; - APLICAÇÃO DA PRIMEIRA FIADA DE CLIPS DE SUPORTE (3) SEGUIDA DAS PLACAS DE REVESTIMENTO (4); - COLOCAÇÃO DOS CLÍPS DE SUPORTE (3) DE REMATE NO TOPO DA FACHADA.
Patent PT-105405-A (PT)
Inventor: FERNANDES VITOR MANUEL GERALDES
IPC: F25C1/12
Filed: 2010-11-26
Abstract: This invention is a controlled freezing process and an apparatus that aims to attenuate the effect of cryoconcentration of solutes that occurs during the freezing of aqueous solutions, by means of a freezing method that gives the user an adequate control of the speed and of the direction of the interface between the solid and the liquid phases in order to incorporate the solutes uniformly in the ice matrix. This invention has applications in the pharmaceutical industry, the food industry and also in the industry for development and commercialization of cryogenic technology.
Patent PT-106225-A (PT)
Title: Processo de expansão ex vivo de células estaminais em biorreactor
Inventor: CABRAL JOAQUIM MANUEL SAMPAIO
IPC: C12N5/074
Filed: 2012-03-23
Abstract: A PRESENTE INVENÇÃO REFERE-SE A UM PROCESSO DE EXPANSÃO EX VIVO DE CÉLULAS ESTAMINAIS, EM BIORREACTOR, DE UM MODO PARTICULAR, DE CÉLULAS ESTAMINAIS/PROGENITORAS HEMATOPOIÉTICAS EM CO-CULTURA COM CÉLULAS ESTAMINAIS DO MESÊNQUIMA IMOBILIZADAS EM MICROTRANSPORTADORES, PARA TRANSPLANTAÇÃO. O PROCESSO COMPREENDE OS PASSOS DE: A) FORMAÇÃO DE UMA SUSPENSÃO DE CÉLULAS ESTAMINAIS DO MESÊNQUIMA IMOBILIZADAS EM MICROTRANSPORTADORES; B) INOCULAÇÃO, NUM BIORREACTOR CONTENDO UM MEIO DE EXPANSÃO, DE CÉLULAS HEMATOPOIÉTICAS EM CO-CULTURA COM AS CÉLULAS ESTAMINAIS DO MESÊNQUIMA IMOBILIZADAS EM MICROTRANSPORTADORES; C) EXPANSÃO DAS CÉLULAS HEMATOPOIÉTICAS. O PROCESSO DA INVENÇÃO É PASSÍVEL DE SER IMPLEMENTADO EM KIT.
Patent PT-115730-A (PT)
Title: Processo para a bioremediação de poluentes derivados dos poços petrolíferos e/ou de gás
Inventor: ANTONIO BERTOLOTTO
IPC: B09C1/10
Filed: 2019-08-14
Abstract: A PRESENTE INVENÇÃO REFERE-SE A UM MÉTODO PARA A BIOREMEDIAÇÃO DE UMA ÁREA POLUÍDA PELA ATIVIDADE DE EXTRAÇÃO DE PETRÓLEO E/OU GÁS NA REFERIDA ÁREA E QUE PROVOCA A EMISSÃO DE GASES POLUENTES NO AR E A POLUIÇÃO DO SOLO E DO SUBSOLO IMPREGNADO DE ÓLEO, COMPREENDENDO UMA OU MAIS DAS SEGUINTES FASES: I) DEPURAÇÃO OU PURIFICAÇÃO DOS GASES PRODUZIDOS POR ESTA ATIVIDADE; II) TRATAMENTO DOS TERRENOS IMPREGNADOS DE ÓLEO PARA SEPARAR AS LAMAS DO ÓLEO; III) MELHORAMENTO DO SOLO.
Patent RU-94002883-A (RU)
Inventor: ZELENEVSKIJ V V
IPC: H04L7/10
Filed: 1994-01-26
Abstract: FIELD: radio engineering. SUBSTANCE: unity and zero symbols are introduced on the transmitting side of modulators, and a unity channel, phase-manipulated signal pattern shaping units, computing circuits, majority element allowing to make a decision on the majority of received symbols are available on the receiving side of the multiplier and intermediate-frequency transformer. EFFECT: enhanced validity of reception of binary information. 1 cl, 2 dwg
Patent RU-94007770-A (RU)
Inventor: ARTEMOV S V
IPC: C08G75/23
Filed: 1994-03-04
Abstract: FIELD: chemical technology. SUBSTANCE: method involves the use of extractant for washing off the finely ground reaction mass of polymer at increased temperatures and using vibrating. After washing off the reaction mass is used for synthesis of poly- and copolyethersulfones which were used as structural and insulating materials and diaphragms in industry and medicine. EFFECT: improved method of isolation and refining. 7 cl
Patent RU-94021720-A (RU)
Inventor: VAREZHKIN JU M
IPC: C02F3/00
Filed: 1994-06-08
Abstract: FIELD: sewage treatment in industry. SUBSTANCE: proposed biochemical method of sewage treatment from organic impurities involves the use of an aqueous solution of 1,3-bis-[dimethyl(t-butylamino)-silyl]-2,2,4,4-tetramethylcyclodisilazane at amount providing the concentration 0.015-0.050 mg/l in cleaning units. Proposed method ensures to improve quality of treatable liquid by 1.7-2.1 times (at retained constant aeration time) or decrease aeration time by 1.44-1.71 times (at the previous cleaning degree). Method is used for sewage treatment from the different organic pollutions. EFFECT: enhanced effectiveness of treatment.
Patent RU-94024075-A (RU)
Inventor: MOISEEV V V
IPC: C08F136/08
Filed: 1994-07-06
Abstract: FIELD: production of synthetic rubber. SUBSTANCE: (co)polymers of dienes are prepared by polymerization of conjugated dienes or by copolymerization of said dienes with each other or with vinylaromatic compounds. The process is carried out in the medium of hydrocarbon solvent in the presence of catalyst, soluble modifying additive being used. Said catalyst contains organolithium compound and hydrocarbon. Mixture of alkyl phenolates of alkali metals and methyl-tert-butyl ether at their molar ratio 1:(0.5-200) is used as mentioned above additive. EFFECT: improves quality of desired copolymers, decreases expense of modifying additive.
Patent RU-94025108-A (RU)
Inventor: KHIZHNJAK N I
IPC: A61B5/00
Filed: 1994-07-15
Abstract: FIELD: medicine, statistics. SUBSTANCE: individual groups of patients having good and abnormal health indices available from clinical studies are selected, statistically significant differences in social and biological disease-producing factors are obtained, including anthropometric characteristics with subsequent constructing the graph of reference values by summing indices representing ratio of factors of risk for persons in question and their actual health state, total effect of biological and social disease-producing factors of person in question is compared with the reference ratio scale and potential of disease occurrence degree is estimated for particular person under study. Device for prognostic screening has the case having inside member rotatable around its central axis and scale with list of disease-producing risk factors and the appropriate numerical values. EFFECT: provides high confidence level. 4 cl, 4 dwg
Patent RU-94029169-A (RU)
Inventor: LIPNJAK L V
IPC: G01M3/00
Filed: 1994-08-03
Abstract: FIELD: testing equipment. SUBSTANCE: equipment includes vacuum chamber to place tested spacecraft, leak detector and three valves connected to unit measuring lack of pressure tightness manufactured in the form of measuring vessel which houses adjustable check leak and pressure transducer, two pipe-lines located inside vacuum chamber connected with one ends via straightway elements of vacuum chamber to proper valves. The other end of first pipe-line is joined to internal space of compartment. The other end of second pipe-line is freely anchored in communication zone of internal space of compartment. Lengths, flow sections and hydraulic resistances of valves with pipe-lines are equal. Pneumatic and hydraulic systems, aggregates and pipe-lines of spacecraft are arranged both inside and outside of compartment. EFFECT: increased authenticity of testing. 1 cl, 1 dwg
Patent RU-94036125-A (RU)
Inventor: BORODULIN JU V
IPC: H02G3/22
Filed: 1994-09-27
Abstract: FIELD: protection of points of connection between external electric cables and conducting lines of hermetically sealed lead-ins against heat and radiation fluxes, water vapors, water, and decontaminating solutions. SUBSTANCE: protective dome is split into hollow thin-walled cylinder and bottom attached to it through sealed joint and loosely mounted on rods built into flange which is installed on lead-in and provided with stuffing boxes combined with cable fastening assemblies. Device is provided with forward and reverse acting safety valves that function to release its mechanical structure from surrounding medium pressure. To prevent moisture condensation inside device, and also to protect it against water vapors, moisture absorbing vessel is mounted in forward-acting valve path on inner side of device. Easily removable heat-shielding casing is mounted on device to protect it against heat fluxes (fire). EFFECT: improved reliability facilitated manufacture and maintenance of safety device.
Patent RU-94045640-A (RU)
Inventor: SHMELEV A JA
IPC: A61K8/98
Filed: 1994-12-30
Abstract: FIELD: perfume and cosmetic industry. SUBSTANCE: creme contains the following ratio of ingredients, mass %: emulsion wax, 2.0-5.0; cosmetic stearin, 2.0-2.5; distilled glycerides, 1.0-3.0; water-free lanolin, 1.0-4.0; olive oil, 9.0-14.0; deodorized mink fat, 3.0-6.0; distilled glycerin, 2.0-5.0; triethanolamine, 0.1-1.0; glucosamineglucans from man's placenta, 0.05-0.5; propyl ether of paraoxybenzoic acid, 0.05-0.5; methyl ethyl of paraoxybenzoic acid, 0.1-0.5; ethyl alcohol, 1.0-4.0; flavor, 0.1-1.0; potable water, the balance. EFFECT: higher efficiency.
Patent RU-95100034-A (RU)
Inventor: STRELKOV V A
IPC: B07B1/28
Filed: 1995-01-20
Abstract: FIELD: manufacture of grain minimills. SUBSTANCE: device has load-carrying frame suspended by ropes for possible rocking. Mounted on frame are sections with sieves and pans with passage for inlet of primary product. Also provided are passages for outflow of ready and intermediate products, unbalanced rocker. Sections with sieves and pans are secured one above other in vertical direction. Passages for outflow of each ready product in all sections are interconnected by vertical passages with outlets in lower part of device. Inlet passages for primary product and outlet passages for intermediate products are made as pan sections protruding beyond the casing. Installed on opposite side of load-carrying frame symmetrically to sections is counterweight. Moments of inertial of all components fastened to the right and left of it are equal. Design of milling unit is simplified despite complex technology due to no additional internal transportation facilities installed. EFFECT: high efficiency.
Patent RU-95103924-A (RU)
Inventor: KHORST KNELLINGER
IPC: B22D41/14
Filed: 1995-03-14
Abstract: FIELD: foundry. SUBSTANCE: method of making shutter for casting ladle make of fire resistant refractory concrete comprises steps of inserting ring 9 of preliminarily made refractory concrete to casting mold 1 in such a way that said ring concentrically embraces pouring duct 6; filling casting mold by paste-like refractory concrete 4, compacting filled mass, drying it and impregnating under pressure. Then carrier carbon embedded into sealing surface of shutter for casting ladle is burnt out at heat treatment in reduction atmosphere with carbon separation. If it is necessary one of several cycles of vacuum heat treatment may be used. Due to insertion of preliminarily make ring 9 and realization of above mentioned steps sliding surface of shutter for casting ladle exhibits super high service properties. Said preliminarily made ring may simultaneously compensate increased loads in zone of pouring duct. EFFECT: enhanced consumer's properties, increased service life period of shutter.
Patent RU-95110578-A (RU)
Inventor: RJUF KHARTMUT
IPC: D04H3/14
Filed: 1994-07-08
Abstract: FIELD: textile industry. SUBSTANCE: invention relates to a method in which cellulose dissolved in tertiary amine oxide is pressed out through die spinneret holes and pressed out elementary threads are fed through air slot with drawing into spinning bath. Method is distinguished with that math expression 51.4 + 0.033 x D+1937 x M-7.18 x L - 2.50 x F + 0.045 x F, where D is hole diameter (mm), M pressed out spinning mass (g/min), T titer of individual thread (dtex), L air slot width (mm), and F air humidity in air slot (g water per 1 kg air) should give maximal number 10 on condition that air slot width is greater than 30 mm. EFFECT: cellulose fibers with insignificant trend to fibrillation manufactured. 6 cl
Patent RU-95112466-A (RU)
Inventor: FOL KER KHAAGER
IPC: D06N3/04
Filed: 1993-11-09
Abstract: FIELD: textile industry. SUBSTANCE: laminated cloth includes synthetic polymer layer disposed between two rubber layers. Point of invention consists in above-mentioned synthetic polymer's being polyvinylidenedifluoride. EFFECT: widened choice of suitable materials.
Patent TW-200300377-A (TW)
Title: Tough and weak crystal mixing for low power grinding
Inventor: EINSET ERIK O
IPC: B24D3/34
Filed: 2002-11-06
Abstract: A resin bond grinding element is composed of a resin bond matrix containing superabrasive particles. The superabrasive particles are an at least 1:1 volume mixture of tough and weak particles, wherein there is at least about 10% difference in toughness between the tough particles and the weak particles. The corresponding method involves grinding a workpiece with a resin bond grinding element composed of a resin bond matrix containing an at least 1:1 volume mixture of tough and weak superabrasive particles, wherein there is at least about 10% difference in toughness between the tough particles and the weak particles. The mixture of tough and weak superabrasive particles also can be used in metal bond and vitreous bond grinding elements.
Patent TW-200305275-A (TW)
Title: Semiconductor memory device
Inventor: NII KOJI
IPC: G11C8/16
Filed: 2002-11-08
Abstract: In a multiport SRAM memory cell of the present invention, an access transistor of a first port is disposed in a p-type well, and an access transistor of a second port is disposed in a p-type well. The gates of all of transistors disposed in a memory cell extend in the same direction. With the configuration, a semiconductor memory device having a low-power consumption type SRAM memory cell with an increased margin of variations in manufacturing, by which a bit line can be shortened in a multiport SRAM memory cell or an associative memory, can be obtained.
Patent TW-200305662-A (TW)
Title: Method for activating surface of base material and apparatus thereof
Inventor: YOSHIDA HIDEO
IPC: C25D5/34
Filed: 2002-11-12
Abstract: A method for activating the surface of a base material and an apparatus thereof, which is suited to be utilized for pretreatment in electrochemical treatment such as, for example, electroplating or the like, in which the surface of a base material such as metal can be subjected to degreasing treatment and oxide film removing treatment simultaneously, efficiently and rationally, in which productivity can be enhanced and the equipment cost can be reduced, and in which a waste solution can be rationalized so that the solution can be reutilized and the environmental pollution can be prevented. A method for activating the surface of a base material in which the surface of a member to be treated is subjected to degreasing treatment or oxide film removing treatment. Pressurized carbon dioxide is dissolved in a predetermined quantity of water, thereby preparing an oxide film removing solution having a predetermined acidic concentration.
Patent TW-200303289-A (TW)
Title: Mesoporous materials and methods
Inventor: WATKINS JAMES J
IPC: C01B33/00
Filed: 2002-11-21
Abstract: Mesoporous articles and methods for making mesoporous articles are disclosed. A method of forming a mesoporous material, the method comprising providing a template comprising a template material; permeating the template with a precursor; reacting the precursor within the template to form a deposit; and removing template material from the template to form the mesoporous material.
Patent TW-200301923-A (TW)
Title: Chemical amplification type photoresist composition, method for producing a semiconductor device using the composition, and semiconductor substrate
Inventor: NAGAHARA SEIJI
IPC: G03F7/004
Filed: 2002-12-03
Abstract: To provide a chemical amplification type positive photoresist composition suited to resist patterning of a substrate presenting surface step differences, a method for manufacturing the semiconductor device employing this composition, and a semiconductor substrate. In a method for manufacturing a semiconductor device, a resist film is formed using a chemical amplification type positive photoresist composition, comprised of a base resin and a basic compound added to the base resin at a rate of 1 to 100 mmol to 100 g of the base resin, on a substrate halving surface step differences and into which the organic removing solution is deposited or oozed, and a predetermined area of the resist film is exposed to light to form a resist pattern.