baber/WOPTO huggingface dataset:
Patent CA-2670887-A1 (CA)
Inventor: BRUNELLE ALAN
IPC: A61K9/26
Filed: 2007-11-28
Abstract: The present invention is a solid dosage form for oral administration of ibuprofen comprising a modified release formulation of ibuprofen which provides an immediate burst effect and thereafter a sustained release of sufficient ibuprofen to maintain blood levels at least 6.4 µg/ml over an extended period of at least 8 hours following administering of a single dose.
Patent CA-2672999-A1 (CA)
Title: Multi-pattern material punch
Inventor: HENKEMEYER SHERRI L
IPC: B26F1/04
Filed: 2007-10-12
Abstract: A system for punching one or more patterns selected from a plurality of related patterns into a workpiece (typically paper or similar materials). The system comprises a punch element having a plurality of cutting surfaces arranged at discrete heights relative to each other, and a means for selecting a discrete distance that the punch element travels through the workpiece.
Patent CA-2674076-A1 (CA)
Inventor: DE JUAN EUGENE JR
IPC: A61B18/18
Filed: 2007-12-21
Abstract: An implant for use with an eye comprises an implantable structure and a therapeutic agent. The therapeutic agent is deliverable from the structure into the eye so as to therapeutically effect and/or stabilize a refractive property of the eye. In many embodiments, the refractive property of the eye may comprise at least one of myopia, hyperopia or astigmatism. The therapeutic agent can comprise a composition that therapeutically effects or stabilizes the refractive property of the eye. The therapeutic agent may comprise at least one of a mydriatic or a cycloplegic drug. For example, the therapeutic agent may include a cycloplegic that comprises at least one of atropine, cyclopentolate, succinylcholine, homatropine, scopolamine, or tropicamide. In many embodiments, a retention element can be attached to the structure to retain the structure along a natural tissue surface.
Patent CA-2675305-A1 (CA)
Title: Gene polymorphisms in vegf and vegf receptor 2 as markers for cancer therapy
Inventor: LENZ HEINZ-JOSEF
IPC: C12Q1/68
Filed: 2008-01-17
Abstract: The invention provides compositions and methods for determining the likelihood of successful treatment with anti-angiogenic antibodies or equivalent thereof, in combination with a pyrimidine based antimetabolite and a platinum-based alkylating agent based therapy. The methods comprise determining the genomic polymorphism present in a predetermined region of a gene of interest and correlating the polymorphism to the predictive response. Patients identified as responsive are then treated with the appropriate therapy.
Patent CA-2676658-A1 (CA)
Title: Modulators of mitotic kinases
Inventor: HONG KEVIN
IPC: A61P35/00
Filed: 2008-01-30
Abstract: The invention relates to compounds of Formula (I), a polymorph, an enantiomer a stereoisomer, a solvate, an N-oxide, or a pharmaceutically acceptable salt thereof; which have inhibitory effect on one or more protein kinases that are involved in cell mitosis.
Patent CA-2681040-A1 (CA)
Title: Super high torque dope-free threaded joint
Inventor: CARCAGNO GABRIEL EDUARDO
IPC: F16L15/06
Filed: 2008-03-27
Abstract: A high torque threaded joint comprising a box member having threads and a pin member having threads (10) configured and positioned to mate with the threads of the box member. There- is a flank- to-flank contact thread profile using trapezoidal threads with both a positive and very low load flank angle, (.beta.1 or a); and a positive and very low stabbin flank (14) angle, (.beta.2, or b), wherein the threads are coated with a solid, dopefree surface treatment.
Patent CA-2683974-A1 (CA)
Title: Protein-modified nano-droplets, compositions and methods of production
Inventor: CHANG CONNIE B
IPC: A61K9/51
Filed: 2008-04-18
Abstract: A protein-modified droplet includes a droplet having a liquid material, and a protein structure formed to at least partially enclose the droplet. The protein structure includes a plurality of protein molecules having an affinity to at least a region of the droplet during formation of the protein structure, and the droplet has a maximum dimension of at least about 1 nm and less than about 1000 nm. A composition includes a plurality of protein-modified droplets dispersed in an aqueous solution.
Patent CA-2685182-A1 (CA)
Title: Osteopontin functional epitopes, monoclonal antibody against the epitopes and uses thereof
Inventor: PENG LING
IPC: A61P35/00
Filed: 2008-03-25
Abstract: Provided are functional epitopes of osteopontin (OPN), monoclonal antibodies that specifically bind to the epitopes, immunoconjugates comprising the monoclonal antibodies and use of the monoclonal antibodies or immunoconjugates for manufacturing a medicament for the treatment of tumor. Also provided are nucleotide sequences encoding the monoclonal antibodies and vectors and host cells comprising the sequences. The monoclonal antibodies or immunoconjugates can be used for detecting the OPN, blocking the promoting metastasis-signaling pathway mediated by OPN and preventing the development and metastasis of tumor, thereby inhibiting the tumor.
Patent CA-2685363-A1 (CA)
Inventor: CONNER CRAIG
IPC: A47L5/28
Filed: 2008-04-29
Abstract: A floor tool is provided, and includes a handle with first and second opposite ends through which a longitudinal axis of the handle extends, and a mop head coupled to the second end of the handle, hi some embodiments, a fluid container is coupled to and carried by the handle at a location between the first and second ends of the handle. The fluid container can have a center of mass offset from the longitudinal axis. In some embodiments, a portion of the handle is located between the fluid container and the first end of the handle, and is offset from the longitudinal axis more than center of mass of the fluid reservoir. The floor tool can also have a valve coupled to the handle and having a gap into which a length of conduit extending from the fluid container can be laterally inserted. A valve-actuating trigger can be coupled to the handle for rotation, such that the trigger pivot point is closer to the second end of the handle than the terminal end of the trigger squeezed by a user.
Patent CA-2686026-A1 (CA)
Title: Cle a serrage automatique
Inventor: WOJICK ROBERT JOHN TERENCE
IPC: B25B13/04
Filed: 2009-11-18
Abstract: Une clé composée d'un manche allongé ayant une extrémité proximale et un premier et deuxième pivots à l'extrémité distale, et un clapet à ressort relié de manière pivotante au deuxième pivot, le clapet pouvant être déplacé relativement au deuxième pivot d'une position déverrouillée à une position verrouillée. La clé comprend une première mâchoire ayant une première extrémité reliée de manière pivotante à la poignée au premier pivot et ayant une deuxième extrémité qui comprend un troisième pivot. Une deuxième mâchoire est reliée de manière pivotante à la première mâchoire grâce au troisième pivot pour constituer une mâchoire articulée avec la première mâchoire. La deuxième mâchoire a une extrémité libre pour déplacer le clapet à ressort de la position déverrouillée à la position verrouillée. Le clapet verrouille l'extrémité libre de la deuxième mâchoire lorsque l'extrémité libre de la deuxième mâchoire est poussée passé le clapet.
Patent CA-2686673-A1 (CA)
Title: Gas sample collection and analysis
Inventor: BRANDESKY JOSEPH A
IPC: G01N1/22
Filed: 2008-05-15
Abstract: A system and method for capturing a sample gas for analysis is disclosed. In one embodiment, the system includes an accumulator that has a variable volume. A volume of the sample gas is fed to the accumulator. The system also has an analyzer. An aliquot of the sample gas is withdrawn from the accumulator and fed to the analyzer. The analyzer analyzes a desired component of the sample gas.
Patent CA-2688747-A1 (CA)
Title: Stem guides and replaceable cartridges
Inventor: BENNIS GARY
IPC: A01K91/03
Filed: 2009-12-17
Abstract: A fishing tackle stem guide is configured to receive a replaceable fishing cartridge and a fishing line. The stem includes a cartridge receiving end and a fishing line engaging end. The cartridge receiving end has a cartridge attachment means configured for receiving and retaining the fishing cartridge to the stem guide in a manner that permits the fishing cartridge to be removed from the stem guide without causing an amount of damage to the stem guide which prevents the stem guide from being used again.  The fishing line engaging end is at an end of the stem guide that is opposite the cartridge receiving end and is configured for receiving a fishing line through an opening in the receiving end, the opening being configured to limit the ability of the line to become separated from the stem guide while allowing the fishing line to pass through the stem guide. The stem guide may be provided in a kit form with a variety of replaceable floats, scent sticks, viz sticks, and light sticks.
Patent CA-2691416-A1 (CA)
Inventor: VAN OPYNEN ADAM
IPC: B21D41/02
Filed: 2008-06-20
Abstract: An assembly for actuating a pipe expander, the assembly comprising a first actuator, arranged to engage a pipe expander head and actuate the same a second actuator, spaced apart from the first actuator and operatively engaged therewith such that operation of the second actuator effects operation of the first actuator to actuate the pipe expander head.
Patent CA-2691729-A1 (CA)
Inventor: HARTWELL EDWARD
IPC: A61M1/00
Filed: 2008-06-27
Abstract: Apparatus (130) for use in wound therapy of mammals is described, the apparatus (130) comprising: a dressing covering the wound, the dressing being substantially sealed to prevent ingress of ambient atmospheric air to the wound; aspiration means (132) operably connected to a space between the dressing and the wound by an aspiration conduit (142) sealed to the point of entry between wound and dressing against ingress of ambient atmosphere, said conduit (142) being for aspiration of said wound and for removal of fluid from said space between said wound and said dressing;  a waste container (148) for receiving aspirated fluid to be discarded operably connected to said aspiration conduit; and heating means (144) for heating said fluid in order to increase the vapour pressure thereof and to cause evaporation to reduce the volume of the fluid in the waste container (148). In a preferred embodiment of the present invention the waste fluid is also provided with a sparge gas.
Patent CA-2692381-A1 (CA)
Inventor: THRANBERG NISSEN RASMUS
IPC: B02C15/00
Filed: 2008-04-28
Abstract: Described is a rolling bearing (1) for a rocker arm, said rolling bearing comprising an at least partly circular outer part (2), an at least partly circular inner part (3) and a number of rolling elements (5) which are fitted between the outer part (2) and the inner part (3). The rolling bearing is peculiar in that at least one of the rolling elements (5) comprises two opposite, curved side faces (6, 7), which viewed in at least one cross-sectional constitutes arc lengths of the same imaginary circle (10), and which constitutes contact faces for the outer and the inner circular part (2, 3) respectively, and at least one side surface (8, 9), which lies within the mentioned imaginary circle (10). It is hereby obtained that the number of rolling elements in the bearing can be increased, thereby reducing the load on each single rolling element subject to the same total load rate, thereby increasing the total load bearing capacity of the bearing. This is due to the fact that at least a part of the roller face of the traditional circular rollers which do not get into contact with the outer or inner part of the bearing through small reciprocating angular rotations is omitted thereby significantly reducing the space taken up by each of the rolling elements in the circumferential direction of the bearing.
Patent CA-2696233-A1 (CA)
Title: Single fuel cell with thickness control layer
Inventor: SHIZUKU FUMISHIGE
IPC: H01M4/86
Filed: 2008-11-28
Abstract: An object of the present invention is to provide a single fuel cell which can suppress mechanical load applied to the electrolyte membrane of the same and apply a sufficient load per unit area of the central region of the same. The object was achieved by a single fuel cell which comprises a membrane electrode assembly and a pair of separators, in which assembly an anode electrode that comprises an anode catalyst layer and a gas diffusion layer is provided on a first surface of a solid polymer electrolyte membrane, and a cathode electrode that comprises a cathode catalyst layer and a gas diffusion layer is provided on a second surface of the solid polymer electrolyte membrane, wherein, on at least one of the anode and cathode sides of the solid polymer electrolyte membrane, the anode or cathode catalyst layer has a size and shape that are slightly smaller than those of the solid polymer electrolyte membrane and those of the gas diffusion layer, and an outer peripheral edge portion of the solid polymer electrolyte membrane and that of the gas diffusion layer stick out of an outer periphery of the anode or cathode catalyst layer and face each other;  wherein a frame-shaped protective layer is provided on at least one of the anode and cathode sides of the solid polymer electrolyte membrane, which has a first part that is present between the outer peripheral edge portion of the electrolyte membrane and that of the gas diffusion layer which face each other, and a second part that overlaps the outer periphery of the anode or cathode catalyst layer; and wherein the single fuel cell comprises a single fuel cell thickness control layer which is thinner in a region of the single fuel cell where the second part of the protective layer is present than in a central region of the single fuel cell where the protective layer is not present, or is not present in the region where the second part of the protective layer is present so that the thickness of the single fuel cell in the region where the second part of the protective layer is present is equal to or smaller than the thickness of the same in the central region where the protective layer is not present.
Patent CA-2697777-A1 (CA)
Inventor: MENDES FLAVIA DUTRA
IPC: C22B3/42
Filed: 2008-08-22
Abstract: A hydrometallurgical resin-in-leach (RIL) process for directly recovering nickel and/or cobalt. Simultaneous pulp leaching by adding an acid or base, dissolves the metals of interest with adsorption of the metals rendered soluble in on ionic exchange resin. Following elution of the changed resin, purification of nickel and cobalt present in the eluate can be recovered by conventional methods, such as precipitation, extraction by solvents and membranes. The regenerated resin is recirculated for further use.
Patent CA-2698487-A1 (CA)
Inventor: SCHAFFER JONATHAN MICHAEL
IPC: A63B5/11
Filed: 2007-09-10
Abstract: Embodiments of hollow generally T-shaped couplers suitable for coupling respective ends of two tubular members to an upright member for a trampoline support are disclosed. Neither manufacture of the coupler nor the manner of its coupling between the tubular members and the upright member requires welds. The coupler has a hollow cross piece for coupling with the respective ends of the two tubular members. It also has a hollow upright piece extending from an underside of and intersecting the cross piece that receives in female fashion a male end of the upright member.  Both the underside of the cross piece and sides of the upright piece are of split form along their respective lengths. The upright piece is provided with location regions that cooperate with corresponding location regions on the male end of the upright member to locate the upright member longitudinally of the upright piece. The coupler is provided with fixings to draw the splits together, thereby tightening the upright piece about the located upright member.
Patent CA-2699367-A1 (CA)
Inventor: KUMAR MAHESH
IPC: A61K39/00
Filed: 2008-09-12
Abstract: The present invention provides live, attenuated Mycoplasma bacteria that exhibit reduced expression of one or more proteins selected from the group consisting of pyruvate dehydrogenase, phosphopyruvate hydratase, 2-deoxyribose-5-phosphate aldolase, and ribosomal protein L35, relative to a wild-type Mycoplasma bacterium of the same species. Also provided are vaccines and vaccination methods involving the use of the live, attenuatedMycoplasma bacteria, and methods for making live attenuated Mycoplasma bacteria.
Patent CA-2700087-A1 (CA)
Title: Structure d'entree d'air apte a etre montee en amount d'une structure mediane de nacelle pour moteur d'aeronef, et nacelle equipee d'une telle structure d'entree d'air
Inventor: VAUCHEL GUY BERNARD
IPC: B64D33/02
Filed: 2008-08-28
Abstract: Cette structure d'entrée d'air, apte à être montée en amont d'une structure médiane de nacelle pour moteur d'aéronef, comprend notamment : une paroi externe (7) intégrant une lèvre (9), apte à être montée mobile par rapport à ladite structure médiane entre une position arrière et une position avant; une cloison (11) définissant un compartiment de dégivrage (13) dans ladite lèvre (9); au moins un collecteur de dégivrage (15) s'étendant dans ledit compartiment (13); et au moins un conduit d'alimentation en air chaud (17) dudit collecteur (15), apte à être relié de manière fixe à ladite structure médiane. Ladite cloison (11) est fixée de manière étanche à l'intérieur de ladite lèvre (9), et ledit conduit d'alimentation (17) est relié audit collecteur (15) par des moyens étanches déconnectables (27, 29, 31, 35).
Patent CA-2700704-A1 (CA)
Inventor: MCALPINE JAMES KENNETH
IPC: E03D9/02
Filed: 2008-09-25
Abstract: An apparatus for a waterless urinal is described. The apparatus comprises a housing defining a chamber for receiving a consumable de-odoriser, the housing including an access device to permit access to the chamber for allowing replacement of the consumable de-odoriser.
Patent CA-2701516-A1 (CA)
Inventor: WEILER SVEN
IPC: C07F9/6506
Filed: 2008-11-26
Abstract: C2-C5-Alkyl-substituted [(imidazol-1 -yl)-1-hy-droxy-l-phosphono-ethyl]-phosphonic acids, as well as methods or processes for their manufacture, their use in the manufacture of pharmaceutical formulations, their use in the treatment of diseases, methods of using them in the treatment of diseases, pharmaceutical formulations encompassing them and/or the compounds for use in the treatment of diseases, are described. The compounds are able to inhibit excessive or inappropriate bone resorption and for the treatment of other diseases which are caused by excessive prenylation of target proteins, such as Hutchinson-Gilford progeria syndrome. The compounds are of the formula (I), wherein one of Rl and R2 is hydrogen and the other is C2-C5-alkyl that is branched or unbranched, and can be in free form, in the form of an ester, and/or of a salt.
Patent CA-2701604-A1 (CA)
Inventor: TSAI MINGLIANG LAWRENCE
IPC: A61F5/44
Filed: 2008-10-20
Abstract: A body interface device for a urine aspiration system comprises a skin contact pad with gel adhesive for adhering to the skin, and a flexible cover attached to the pad. The pad includes at least one aperture for admitting urine through the pad into the body interface device. The flexible cover has a bulged form projecting away from the gasket. The flexible cover defines a urine receiving chamber facing towards the gasket, and recess facing away from the chamber for receiving at least a portion of a non-contact liquid sensor. The recess and chamber have a wall portion in common that separates the recess and the chamber. A liquid acquisition material in the chamber receives and transports urine for rapid sensing by the non-contact sensor. An aspiration unit is responsive to the non-contact liquid sensor to apply aspiration suction to the body interface device, upon detection of urine.
Patent CA-2702122-A1 (CA)
Inventor: JOHANSSON NILS
IPC: F42B30/00
Filed: 2008-10-16
Abstract: The present invention relates to a method and a shell (1) for achieving variable firing range and effect when firing from a launcher, which shell (1) contains a firing charge (10), a rocket motor charge (6) with gas outlet (8), a rocket motor nozzle (9) and an active part (5). According to the invention, this is achieved by virtue of the fact that the shell (1) also contains a release mechanism (15) for releasing the rocket motor nozzle (9) from the rocket motor charge (6) after a time delay determined with regard to firing range and effect, and that the rocket motor charge (6) comprises a propellant which is detonable.
Patent CA-2703641-A1 (CA)
Inventor: GLENN BRIAN
IPC: F03D1/06
Filed: 2009-01-14
Abstract: The invention relates to a modular rotor blade for a power generating turbine that allows simple replacement of individual rotor blade sections in case of damage to or malfunction of a section. The modular rotor blade comprises at least two rotor blade sections (10, 11), wherein each rotor blade section (10, 11) comprises at least one connecting part (14, 16) having at least one conical opening (41, 42), the connecting parts (14, 16) of adjacent rotor blade sections (10, 11) rest against each other such that the conical openings (41, 42) of the connecting parts (14, 16) are aligned with each other and form a continuous conical connecting opening, receiving means (18) for receiving tensioning means (28) are arranged at the smaller diameter end of the conical connecting opening, a conical bolt (30) corresponding to the continuous conical connecting opening is arranged therein, and at least one tensioning means (28) passing through the conical bolt (30) and tensioning the conical bolt (30) against the receiving means (18).
Patent CA-2704178-A1 (CA)
Inventor: CHANG YUNG-FU
IPC: A61K39/04
Filed: 2008-10-09
Abstract: Provided are compositions and methods for stimulating an immune response against Mycobacterium avium subspecies paratuberculosis (MAP). The compositions include a recombinant polypeptide that contains from its N-terminus to C-terminus a C-terminal fragment of MAP protein Map3527, a Map1519 protein amino acid sequence, followed by an N-terminal portion of Map3527. The method comprises administering the composition to an animal in an amount effective to stimulate an immunological response against MAP bacteria. The method is of benefit to any animal susceptible to MAP infection, but is particularly beneficial for ruminants.
Patent CA-2706620-A1 (CA)
Title: Conjugated beta-1,3-linked glucans
Inventor: BERTI FRANCESCO
IPC: A61K47/36
Filed: 2008-11-26
Abstract: Glucans having exclusively or mainly .BETA.-1,3 linkages are used as immunogens. These comprise .beta.-1,3-linked glucose residues. Optionally, they may include .beta.-1,6-linked glucose residues, provided that the ratio of .beta.-1,3-linked residues to .beta.-1,6-linked residues is at least 8: 1 and/or there are one or more sequences of at least five adjacent non-terminal residues linked to other residues only by 0-1,3 linkages. The glucans will usually be used in conjugated form. A  preferred glucan source is curdlan, which may be hydrolysed to a suitable form prior to conjugation.
Patent CA-2707621-A1 (CA)
Inventor: WILDER GREGORY WINSTON
IPC: G10G1/00
Filed: 2007-12-31
Abstract: The present invention comprises a system and method, modeled on research observations in human perception and cognition, capable of accurately segmenting primarily (although not exclusively) melodic input in performance data and encoded digital audio data, and mining the results for defining motives within the input data.