baber/WOPTO huggingface dataset:
Patent EA-016419-B1 (EA)
Title: Method for the preparation of 5-benzyloxy-2-(4-benzyloxphenyl)-3-methyl-1h-indole
Inventor: JIRMAN JOSEF
IPC: C07C217/80
Filed: 2008-02-11
Abstract: A method for the preparation of 5-benzyloxy-2-(4-benzyloxyphenyl)-3-methyl-1H-indole of formula (1) by reaction of 2-bromo-4'-benzyloxypropiophenone and 4-benzyloxyaniline hydrochloride, in which high purity of the product is achieved by isolation of the intermediate, N-(4-benzyloxyphenyl)-a-amino-4-benzyloxypropiophenone of formula (10), in the solid state. The method may be used for the preparation of bazedoxifen of formula (2).
Patent EA-018334-B1 (EA)
Title: Drilling fluid containing carbon nanotubes
Inventor: PASSADE-BOUPAT NICOLAS
IPC: C09K8/03
Filed: 2008-08-29
Abstract: The present invention relates to a viscoelastic drilling fluid for drilling in subterranean rock formations, which comprises: (a) an aqueous and/or organic liquid base; (b) at least one weighting agent, in particulate form, having a density at least equal to 2 g/cm, preferably at least equal to 4 g/cm, in suspension in said liquid base; and (c) carbon nanotubes having a mean diameter between 10 and 30 nm and a specific surface area greater than 200 m/g, preferably between 200 and 250 m/g. The invention also relates to a drilling method using such a fluid.
Patent EA-019977-B1 (EA)
Title: Process to make olefins from organics
Inventor: NESTERENKO NIKOLAI
IPC: B01J27/16
Filed: 2009-06-24
Abstract: The present invention relates to a process to make light olefins, in a combined XTO-OC process, from an oxygen-containing, halogenide-containing or sulphur-containing organic feedstock comprising: a0) providing a first portion and a second portion of said oxygen-containing, halogenide-containing or sulphur-containing organic feedstock; a) providing a catalyst comprising zeolitic molecular sieves containing at least 10 membered ring pore openings or larger in their microporous structure; b) providing an XTO reaction zone, an OC reaction zone and a catalyst regeneration zone, said catalyst circulating in the three zones, such that at least a portion of the regenerated catalyst is passed to the OC reaction zone, optionally at least a portion of the catalyst in the OC reaction zone is passed to the XTO reaction zone and at least a portion of the catalyst in the XTO reaction zone is passed to the regeneration zone; c) contacting the first portion of said oxygen-containing, halogenide-containing or sulphur-containing organic feedstock in the XTO reactor with the catalyst at conditions effective to convert at least a portion of the feedstock to form a XTO reactor effluent comprising light olefins and a heavy hydrocarbon fraction; d) separating said light olefins from said heavy hydrocarbon fraction; e) contacting said heavy hydrocarbon fraction and the second portion of said oxygen-containing, halogenide-containing or sulphur-containing organic feedstock in the OC reactor with the catalyst at conditions effective to convert at least a portion of said heavy hydrocarbon fraction and oxygen-containing, halogenide-containing or sulphur-containing organic feedstock to light olefins.
Patent EA-022175-B1 (EA)
Title: Thermally insulated tube
Inventor: LUENSTEDT FRANK
IPC: F16L59/147
Filed: 2009-10-13
Abstract: The invention relates to a tube system, comprising at least one media tube (1), at least one thermal insulation layer (2) containing polyolefins, and at least one outer sheathing (3), characterized in that the thermal insulation layer (2) has an external profile that follows the outer sheathing (3).
Patent EA-018773-B1 (EA)
Title: Waterproof and vapor-permeable shoe
Inventor: POLEGATO MORETTI MARIO
IPC: A43B7/08
Filed: 2010-03-12
Abstract: A waterproof and vapor-permeable shoe, which comprises a sole (11, 111), provided with a vapor permeation region (12, 112), an assembly insole (13), which is covered, toward the sole (11, 111), by at least one first gasket (14) made of waterproof material, which has at least one vapor-permeable or perforated portion (15) above the vapor permeation region (12, 112), which, once assembled, covers an upper shoe assembly (16), which comprises at least one vapor-permeable lining (17), a vapor-permeable upper (18), and a waterproof and vapor-permeable upper membrane (19) that is between them, the upper shoe assembly (16) being associated with the assembly insole (13) at least predominantly according to the construction known as "AGO lasting", at least one second gasket (20), made of waterproof material, which adheres so to form a waterproof seal to the first gasket (14); and is glued to the lower edge (18a) of the upper (18), which it surmounts, the second gasket (20) forming a waterproof sealing region of the upper shoe assembly (16) and the first gasket (14) to the sole (11, 111), leaving free for vapor permeation at least the vapor-permeable or perforated portion (15).
Patent EA-021240-B1 (EA)
Title: 5,6-dihydro-2h-[1,4]oxazin-3-ylamine derivatives useful as inhibitors of beta-secretase (bace)
Inventor: TRABANCO-SUAREZ ANDRES AVELINO
IPC: C07D413/04
Filed: 2011-06-08
Abstract: The present invention relates to novel 5,6-dihydro-2H-[1,4]oxazin-3-ylamine derivatives as inhibitors of beta-secretase, also known as beta-site amyloid cleaving enzyme, BACE, BACE1, Asp2, or memapsin 2. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which beta-secretase is involved, such as Alzheimer's disease (AD), mild cognitive impairment, senility, dementia, dementia with Lewy bodies, Down's syndrome, dementia associated with stroke, dementia associated with Parkinson's disease and dementia associated with beta-amyloid.
Patent EA-028379-B1 (EA)
Title: Pane comprising an electrical connection element
Inventor: DEGEN CHRISTOPH
IPC: H05B3/84
Filed: 2012-04-17
Abstract: The present invention relates to a pane provided with at least one electrical connection element, comprising a substrate (1), an electroconductive structure (2) on a region of the substrate (1), a layer of a soldering material (4) on a region of the electroconductive structure (2) and a connection element (3) on the soldering mass (4), wherein the connection element (3) contains a first and a second base regions (7, 7'), a first and a second transition regions (9, 11), and a bridge region (10) between the first and second transition regions (9, 11); a first and a second contact surfaces (8, 8') are arranged on the lower side of the first and second base regions (7, 7'); the first and second contact surfaces (8, 8') and the surfaces (9', 11') of the first and second transition regions (9, 11), facing the substrate (1), are connected to the electroconductive structure (2) by means of the soldering mass (4); and the angle between the surface of the substrate (1) and each of the tangential planes (12) of the surfaces (9', 11') of the transition regions (9, 11), facing the substrate (1), amounts to <90°.
Patent EA-034414-B1 (EA)
Title: Method for treating triple-negative breast cancer
Inventor: TREMBLAY GILLES BERNARD
IPC: A61P35/00
Filed: 2013-01-09
Abstract: Breast cancer cells lacking ER protein expression, PgR protein expression and/or showing absence of HER2 protein over-expression (i.e., triple-negative breast cancer cells, basal-like) can be efficiently targeted with an anti-KAAG1 antibody and killed upon delivery of a therapeutic moiety. Antibodies and antigen binding fragments that specifically bind to KAAG1 may thus be used for the detection and therapeutic treatment of breast cancer cells that are negative for at least one of these markers. The use of antibody conjugates in the treatment of triple-negative breast cancer and/or basal-like breast cancer is disclosed herein.
Patent EA-028483-B1 (EA)
Title: Diazacarbazole derivatives as pet-ligands of tau protein
Inventor: GOBBI LUCA
IPC: A61K31/44
Filed: 2014-10-06
Abstract: The invention relates to a compound of general formulawherein R is hydrogen or tritium; F is fluoro orfluoro; or to a pharmaceutically acceptable acid addition salt. Compounds of formula I include 2-(6-fluoro-pyridin-3-yl)-9H-dipyrido[2,3-b;3',4'-d]pyrrole,H-2-(6-fluoro-pyridin-3-yl)-9H-dipyrido[2,3-b;3',4'-d]pyrrole and [F]-2-(6-fluoro-pyridin-3-yl)-9H-dipyrido[2,3-b;3',4'-d]pyrrole. The compounds may be used for binding and imaging tau aggregates and related beta-sheet aggregates including besides others beta-amyloid aggregates or alpha-synuclein aggregates.
Patent EA-036658-B1 (EA)
Title: Anti-il-25 antibodies and uses thereof
Inventor: ORENGO JAMIE M
IPC: A61K39/395
Filed: 2015-09-22
Abstract: The present invention provides antibodies that bind to human interleukin-25 (IL-25) and methods of using the same. According to certain embodiments, the antibodies of the invention bind human IL-25 with high affinity. In certain embodiments, the invention includes antibodies that bind human IL-25 and block IL-25-mediated cell signaling. The antibodies of the invention may be fully human, non-naturally occurring antibodies. The antibodies of the invention are useful for the treatment of various disorders associated with IL-25 activity or expression, including asthma, allergy, chronic obstructive pulmonary disease (COPD), inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, atopic dermatitis (AD), and Eosinophilic Granulomatosis with Polyangiitis (EGPA), also known as Churg-Strauss Syndrome.
Patent EA-033264-B1 (EA)
Title: C-3 novel triterpenone with c-17 reverse amide derivatives as hiv inhibitors
Inventor: PARTHASARADHI REDDY BANDI
IPC: A61P31/18
Filed: 2016-02-09
Abstract: The invention relates to C-3 novel triterpenone with C-17 reverse amide derivatives and related compounds, and pharmaceutical compositions useful for the therapeutic treatment of viral diseases, particularly HIV mediated diseases.
Patent EA-034070-B1 (EA)
Title: Method of supplementation of the nutrition of an adult
Inventor: KESLER URIEL
IPC: A23L33/00
Filed: 2014-02-12
Abstract: The present invention relates to a method of supplementation of the nutrition of an adult comprising adding to the nutrition a composition comprising an almond component pre-treated to lower the levels of phytic acid and a non-dairy component comprising all essential amino acids, represented by at least one type of grain pre-hydrolized or pre-gelatinized.
Patent EA-036074-B1 (EA)
Title: Retractable syringe
Inventor: WALSH ALLAN
IPC: A61M5/50
Filed: 2016-11-18
Abstract: An auto-retractable syringe having a barrel and a plunger wherein engagement of said plunger with an otherwise immobilised needle hub allows a biasing member to push the needle hub into a cavity in the plunger.
Patent EA-037170-B1 (EA)
Title: Rail vehicle having crane rails for a gantry crane
Inventor: HOETZENDORFER PATRICK
IPC: E01B29/02
Filed: 2017-10-06
Abstract: The invention relates to a rail vehicle (1), having a machine frame (2), which is supported on rail bogies (4) and on which crane rails (8) for a movable gantry crane (11) are arranged on both sides in the rail vehicle longitudinal direction (3). A crane rail section (12) of each crane rail (8) is arranged for height adjustment by means of a drive (18) in order to lower or raise the gantry crane (11). Thus, in comparison with the prior art, a higher gantry crane (11) can be used without violating a specified clearance profile during transfer trips.
Patent EA-036249-B1 (EA)
Title: Suspension arrangement for anode beams in electrolytic cells of hall-heroult type for the production of aluminum and method for stabilizing the operation of such cells
Inventor: WEDERSHOVEN ELMAR
IPC: C25C3/10
Filed: 2017-12-04
Abstract: A suspension arrangement for anode beams in electrolytic cells of Hall-Heroult type for the production of aluminum including an anode superstructure and an elongated generally horizontally disposed anode beam (AB) supporting prebaked anodes, where the suspension arrangement is provided for supporting said anode beam from said anode superstructure for movement relative thereto. The anode beam is divided into two anode bar sections (A) and (B), aligned one after the other in the longitudinal direction of the cell, where each anode bar section is provided with two jacks (J1, J2) and (J3, J4) and has torsional devices (L1, L2) and (L3, L4) arranged at or near the ends of each of said anode bar sections. The invention also relates to a method for stabilizing the operation of an electrolytic cell of Hall-Heroult type for the aluminium production, by operation of the suspension arrangement.
Patent ES-2169675-B1 (ES)
Title: Producto con propiedades antiinflamatorias para el colon humano.
Inventor: MALAGELADA BENAPRES RAMON
IPC: A61K35/747
Filed: 2000-07-19
Granted: 2003-04-16
Abstract: Producto con propiedades antiinflamatorias para el colon humano. El producto se caracteriza por comprender la bacteria Lactobacillus casei DN114001 contenida en un vehículo que permite su liberación en el colon humano, constituyendo el vehículo mediante leche fermentada o vehículo entérico.
Patent ES-2170695-B1 (ES)
Title: Tapa reforzada para electrodomesticos y trodomesticos y procedimiento para su fabricacion.
Inventor: VIVES CLAVEL JUAN
IPC: D06F39/12
Filed: 2000-08-24
Granted: 2003-11-01
Abstract: Perfeccionamientos introducidos en la patente de invención nº.200001692 por tapa reforzada para electrodomésticos y procedimiento para su fabricación. Los perfeccionamientos sobre la estructura de la tapa reforzada consiste en que se modifica la configuración de la unión panel (5)-marco (7) de forma que éste, en lugar de abrazar por sus bordes al panel (5), se sobrepone al mismo por su zona perimetral superior, quedando unidas ambas piezas por un cordón de adhesivo (8) que contornea la cara inferior o interna del panel (5), entre el borde del mismo y la cara interna de las paredes del marco (7), quedando recubierto el panel (5) con papel melaminizado (6) adherido con cola termoactiva a la cara superior del plano de la tapa.
Patent ES-2185460-B1 (ES)
Title: Microparticula de liberacion prolongada y metodo para su preparacion.
Inventor: PARK JIN KYU
IPC: A61K9/50
Filed: 2000-10-17
Granted: 2004-06-16
Abstract: Micropartícula de liberación prolongada y método para su preparación. Se describe un método para preparar micropartículas de liberación prolongada que liberan una sustancia fisiológicamente activa durante periodos de tiempo prolongados. Se prepara las micropartículas de liberación prolongada mediante un proceso multiemulsión. Se disuelve o se dispersa una droga de interés en cada uno de por lo menos dos aceites para dar al menos dos fases o emulsiones de aceites primarias. Cada fase o emulsión de aceite contiene un polímero biodegradable. Las dos fases o emulsiones de aceite primarias por lo menos se dispersan en una fase acuosa, de manera síncrona o en sucesión. De la solución dispersada de la droga se retira los disolventes orgánicos para producir micropartículas. Por consiguiente, las drogas tales como hormonas liberadoras de hormona luteinizante pueden liberarse continuamente in vivo durante periodos de tiempo prolongados, consiguiéndose una mejora en el efecto terapéutico.
Patent ES-2205996-B1 (ES)
Title: Set of rods of ice comprises frozen water in an e.g. metal mold of specific configuration
Inventor: PEREZ LINDE ANGEL JOAQUIN
IPC: F25C1/24
Filed: 2001-12-07
Granted: 2005-07-16
Abstract: The set of rods of ice consists of water in a mold (1) with cavities (2) producing the rods (3) on freezing. The rod cross-section (4) does not exceed the dimensions e.g. of bottles and demijohns.
Patent ES-2255789-B1 (ES)
Title: Cuna flexi de tres puntos de anclaje y tres grados de movimiento para chasis de coches de slot.
Inventor: CONDE RODRIGUEZ ARTURO
IPC: A63H17/26
Filed: 2003-10-13
Granted: 2007-07-01
Abstract: La Cuna Flexi de tres puntos de anclaje y tres grados de movimiento para chasis de coches de Slot, que se acopla a éste a través de tres anclajes, uno delantero que es cilíndrico (15) y los dos traseros con dos orificios roscados (13) que se unen al chasis mediante dos tornillos (26). Además esta cuna lleva un sistema de dos muelles que se apoyan en sendos brazos (16) con la finalidad obtener un efecto de suspensión. Con este tipo de cuna obtenemos tres grados de movimientos que mejoran la estabilidad del coche en la pista, o sea, tendrá un movimiento oscilatorio a un lado y a otro del eje de simetría longitudinal, tendrá otro de cizalla horizontal y otro oscilatorio vertical. Los tres son para mejorar la absorción de las inercias indeseables además de aproximar o alejar el chasis a la pista.
Patent ES-2255377-B1 (ES)
Title: Sistema de aparcamiento de vehiculos en dos alturas con autonomia en ambas plazas.
Inventor: MARTINEZ BASTOS FERNANDO
IPC: E04H6/06
Filed: 2004-02-24
Granted: 2007-07-16
Abstract: Sistema de aparcamiento de vehículos en dos alturas con autonomía en ambas plazas. Tiene especial aplicación en aparcamientos de superficie en la vía pública y en línea, aumentando así el número de aparcamientos. Incluye una estructura modular (1) independiente para cada puesto de aparcamiento doble, provista de una plataforma inferior (2) desplazable en su plano, y otra plataforma superior (3) de desplazamiento vertical. La plataforma inferior (2) y el bastidor de la estructura desplazable (1) se mueven sobre guías (4) fijadas transversalmente a la calzada. Cuando avanza el bastidor, la plataforma inferior (2) permanece inmóvil y así puede descender hasta el suelo la plataforma superior (3) para recoger o descargar un vehículo. Para cargar o descargar un vehículo de la plataforma inferior (2), la superestructura completa sale y después retrocede.
Patent ES-2245263-B1 (ES)
Title: Persiana enrollable.
Inventor: AURIA PEREZ AGUSTIN
IPC: E06B9/78
Filed: 2005-04-04
Granted: 2007-07-01
Abstract: Persiana enrollable, que comprende un grupo (A), consistente en la caja (1) del eje (4) de la persiana, rodamientos (5) y lamas (6), que incorpora un acoplamiento (7) que encaja con un acoplamiento (15) de un grupo superior (B), que comprende una caja (9), del eje del carrete superior (10) rodamientos (11, 12) y el carrete superior (13) con la cinta (14) siendo independiente del grupo (A); y un grupo inferior (C) que comprende una caja (25) del carrete inferior (26) su eje, el freno (27) de la cinta (14), que junto con el grupo superior (B), son un elemento unificado.
Patent ES-2316210-B1 (ES)
Title: Dispositivo de impresion por transferencia de calor.
Inventor: PENZO MIRKO
IPC: B41J2/325
Filed: 2005-12-30
Granted: 2010-01-11
Abstract: Dispositivo de impresión por transferencia de
calor. 
     Dispone de al menos un rodillo guía de entrada
(1) que dirige una cinta  de impresión (2) hacia un tambor (3)
ubicado a continuación de un cabezal  térmico de impresión (10) y
con anterioridad a unos rodillos guía de salida  (4). Incorpora un
rodillo basculante (5) que gira en torno al tambor (3)  con la cinta
de impresión (2) situada entre ambos, conformando un bucle  de cinta
de impresión (2) sobre el tambor (3) que determina una tensión  de
la cinta (2) durante la impresión.
Patent ES-2292357-B1 (ES)
Title: Exprimidor de citricos.
Inventor: HUBER LUKAS WERNER
IPC: A47J19/02
Filed: 2006-08-31
Granted: 2009-02-01
Abstract: Exprimidor de cítricos. Comprende una cavidad apta para recibir una porción de cítrico cortado formada por un lienzo flexible que define una pared lateral anular flexible (1) que rodea y envuelve dicha porción de cítrico, y un elemento receptor y encauzador de líquido (2) que constituye un fondo para dicha cavidad. El elemento receptor y encauzador de líquido (2) tiene un perímetro conectado a un borde (1a) de dicha pared lateral anular flexible (1) y una abertura (3) para salida del zumo exprimido, la cual está dimensionada para retener las pepitas. El lienzo flexible es capaz de ser empujado contra la porción de cítrico cortado dispuesto en la cavidad para exprimirlo. Opcionalmente incluye medios para cerrar la abertura de salida cuando no está en uso. Preferiblemente el exprimidor es de una sola pieza moldeada de un polímero flexible, por ejemplo, silicona catalizada con platino.
Patent ES-2343993-B1 (ES)
Title: Encofrado redimensionable para la construccion "in situ" de nichos y columbarios.
Inventor: MASSO SABRIA JOSE
IPC: B28B7/16
Filed: 2008-02-07
Granted: 2011-06-06
Abstract: Encofrado redimensionable para la construcción
" in situ " de nichos y columbarios provisto de medios
para su desencofrado mecánico y reutilización progresiva que es un
encofrado recuperable dividido longitudinalmente en dos partes
simétricas, comprendiendo una pieza suplemento que se intercalada
entre ambas, dando opción a la redimensión de dicho encofrado para
obtener un ancho mayor al del encofrado básico y comprendiendo
asimismo un suplemento disponible en los bordes de la base de las
partes simétricas para obtener una mayor altura que la del encofrado
básico, uniéndose entre sí mediante una disposición de nervios y
pestañas y fijándose por medio de tornillos, pernos o similares.
Patent ES-2325294-B1 (ES)
Title: Metodo mejorado para la instalacion en obra de materiales de aplacado tales como baldosas ceramicas, piedras naturales, maderas, mosaicos.
Inventor: GIL VALLS JUAN
IPC: B44C1/28
Filed: 2008-02-28
Granted: 2010-06-11
Abstract: Método mejorado para la instalación en obra de
materiales de aplacado tales  como baldosas cerámicas, piedras
naturales, maderas, mosaicos. La presente  invención se refiere a un
método para la realización de placas de acabado  y conjunción de
piezas de mosaico de cualquier naturaleza, tanto materiales 
naturales como prefabricados, mediante una lámina polimérica
autoadhesiva  a una o dos caras en forma de placa instalada por su
parte posterior, con  el fin de obtener un producto terminado con
mayores ventajas en su instalación  definitiva en obra. La invención
es aplicable a todo tipo de materiales  usados como elementos de
acabado en el sector de la construcción, tanto  materiales naturales
como artificiales, en placas rígidas o bien en mosaicos, 
recogiéndose en esta invención en concreto la aplicación del método
tanto  a la producción industrial tanto de mosaicos como de baldosas
de acabado.
Patent ES-2384836-B1 (ES)
Title: Sistema de antena tipo reflectarray.
Inventor: GEORGIADIS APOSTOLOS
IPC: H01Q3/42
Filed: 2009-09-01
Granted: 2013-05-20
Abstract: Sistema de antena tipo reflectarray.#El reflectarray comprende una pluralidad de celdas integradas en una PCB (1) e iluminadas externamente mediante una señal de entrada (3) a partir de una fuente de alimentación (2) a una frecuencia f{sub,i}, y se refleja una señal de salida (4). Cada celda del reflectarray es una AIA formada por un elemento radiante pasivo conectado a un circuito activo, que puede ser o bien un oscilador, o bien un oscilador en contrafase paralelo o un SOM. El circuito radiante pasivo se coloca sobre una superficie reflectora que forma un lado (1A) del reflectarray y el circuito activo se coloca sobre el lado opuesto (1B). El circuito activo produce una señal de salida con una frecuencia relacionada con la frecuencia de entrada f{sub,i} y la frecuencia de oscilación f{OSC} de dicho circuito activo. Esta relación de fase se determina por una variación de fase de salida, que se controla mediante medios electrónicos integrados en el sistema de reflectarray, que permite un intervalo de variación de fase de salida incluso superior a 180º.