baber/WOPTO huggingface dataset:
Patent NZ-508950-A (NZ)
Title: Cancer treatment methods using antibodies to aminophospholipids
Inventor: THORPE PHILIP E
IPC: A61K47/48
Filed: 1999-07-12
Abstract: A composition comprising a biologically effective amount of an anti-aminophospholipid antibody, or antigen- binding region thereof, wherein the anti-aminophospholipid antibody is not an anti-phosphatidylserine antibody obtained from a patient with an anti-phospholipid autoimmune disease, for use in killing tumor vascular endothelial cells in an animal having a vascularized tumor. The anti-aminophospholipid antibody can be prepared by in vitro stimulation of a mixed population of human peripheral blood lymphocytes with an immunogenically effective amount of an aminophospholipid sample; immunizing a non-human animal with an immunogenically effective amount of an aminophospholipid sample, then immunizing a transgenic mouse that comprises a human antibody library with an immunogenically effective amount of an aminophospholipid sample and then obtaining and either expressing an anti- aminophospholipid antibody-encoding nuclei acid or selecting and expressing an anti-aminophospholipid antibody- encoding nucleic acid from a combinatorial immunoglobin phagemid library expressing RNA isolated form the spleen of an animal immunized with an effective amount of an aminophospholipid sample. Also described is a kit comprising the composition and a diagnostically effective amount of a detectably labeled antibody that binds to an aminophospholipid.
Patent NZ-509726-A (NZ)
Title: Compressed air assisted fuel injection system
Inventor: COBB WILLIAM T
IPC: F02B27/02
Filed: 1999-07-19
Abstract: An internal combustion engine having a compressed air assisted fuel injection system. The injection system has a compressed air accumulator with a first aperture into the cylinder of the engine and a second aperture into the crankcase of the engine. The two apertures are located at opposite ends of the accumulator and the accumulator has a tube shape. The accumulator blows off pressure every time one of the ports into the cylinder is closed. The tube shape of the accumulator forms a tuned reflection pipe for a compression wave from the cylinder to generate a reflected compression wave for assisting in delivering fuel and air into the cylinder. The two apertures are adapted to be opened and closed by the piston head of the engine
Patent NZ-510786-A (NZ)
Title: Method of formulating alkali metal salts
Inventor: PHINNEY ROBIN
IPC: C01D5/08
Filed: 1999-09-30
Abstract: A method of formulating potassium sulfate and food grade sodium bicarbonate is described.  The method involves; a) providing a source of liquid sodium sulfate; b) providing a source of ammonium bicarbonate to precipitate sodium bicarbonate; c) contacting the sodium sulfate and the ammonium bicarbonate; d) precipitating sodium bicarbonate and forming a liquor; e) filtering the sodium bicarbonate; f) saturating liquor form step e) with sodium sulfate; g) contacting the liquor with ammonium carbonate ammonia gas or carbon dioxide to precipitate further sodium bicarbonate; h) filtering precipitated sodium bicarbonate from step g); i) combining sodium bicarbonate precipitate from step e) and h) and washing to form food grade sodium bicarbonate; j) cooling the liquor from step i) to 0oC to at least form a Glauber's salt precipitate; k) treating the liquor from step j) with sulfuric acid to convert carbonate minerals and release carbon dioxide gas; l) heating the liquor from step k) to between 30oC and 40oC; and m) precipitating potassium sulfate by contacting the liquor from step l) with potassium chloride.
Patent NZ-516595-A (NZ)
Title: Conjugates of sodium channel blockers and methods of using the same
Inventor: BOUCHER RICHARD C
IPC: A61P11/12
Filed: 2000-07-19
Abstract: Compounds of the general formula P1-L-P2, wherein: "P1" is a pyrazinoylguanidine sodium channel blocker, "L" is a linking group, and "P2" is either (i) a pyrazinoylguanidine sodium channel blocker or (ii) a P2Y2 receptor agonist, are disclosed. Pharmaceutical formulations containing these compounds and methods of use thereof to hydrate mucosal surfaces such as airway mucosal surfaces are also disclosed
Patent NZ-517609-A (NZ)
Title: Embryonic or stem-like cell lines produced by cross species nuclear transplantation and methods for enhancing embryonic development by genetic alteration of donor cells or by tissue culture conditions
Inventor: ROBL JAMES
IPC: A61K35/12
Filed: 2000-09-14
Abstract: A method of nuclear transfer involving the transplantation of differentiated donor cell nuclei into enucleated oocytes of a species different from the donor cell is disclosed. The resultant nuclear transfer units are useful for the production of isogenic embryonic stem cells, in particular human isogenic embryonic or stem cells. These embryonic or stem-like cells are useful for producing desired differentiated cells and for introduction, removal or modification, of desired genes, e.g., at specific sites of the genome of such cells by homologous recombination. These cells, which may contain a heterologous gene, are especially useful in cell transplantation therapied and for in vitro study of cell differentiation. Methods for improving nuclear transfer efficiency by genetically altering donor cells to inhibit apoptosis, select for a specific cell cycle and/or enhance embryonic growth and development are also disclosed.
Patent NZ-518755-A (NZ)
Title: Suspension comprising oxcarbazepine
Inventor: SIGG JUERGEN
IPC: A61K31/55
Filed: 2000-12-19
Abstract: An oral suspension form of oxcarbazepine having improved physico-chemical properties (e.g. stability and porability), comprising oxcarbazepine and carboxymethylcellulose and microcrystalline cellulose.
Patent NZ-527652-A (NZ)
Title: Dispensing apparatus
Inventor: CROSSDALE GARY WILLIAM
IPC: B67D3/02
Filed: 2002-02-14
Abstract: The dispensing apparatus dispenses material into a container (34) having at least one predetermined shape component (40a) which cooperates with the dispensing apparatus to control a dispensing operation. There is a vertically movable support (8) for the container having a first, lower position at which the container is brought into a mounted position on the support and a second, higher position, and actuating means (24a,30) arranged for mechanical engagement with the container during lifting of the container on the support. The actuating means cooperates with the predetermined shape component or components of the container to determine, in dependence on the shape of the shape component the liquid or liquids to be dispensed into the container, and/or the quantity of a liquid to be dispensed into the container. The actuating means (24a,30) lifts cylinders (22,24) to dispense the liquid
Patent NZ-527720-A (NZ)
Title: Synthetic vaccine agents
Inventor: NIELSEN KLAUS GREGORIUS
IPC: A61K/
Filed: 2002-02-19
Abstract: An immunogen comprises at least one antigenic determinant constituted by an amino acid sequence that includes at least one B-cell epitope and/or at least one CTL epitope, and at least one second antigenic determinant constituted by an amino acid sequence that includes a T helper cell epitope (TH epitope). Each of the antigenic determinants are independently coupled through the nitrogen atoms at their respective NB-termini to a pharmaceutically acceptable activated polyhydroxypolymer carrier via a bond that is cleavable. The immunogen can be used in the manufacture of a medicament for immunizing an animal.
Patent NZ-528212-A (NZ)
Title: Device for securing the handle of a container which is placed on a mixing machine
Inventor: AVANZI ROBERTO
IPC: B44D3/08
Filed: 2002-03-28
Abstract: A device for securing the handle of a container placed on a mixing machine of the type comprising support means (10, 12) for the container comprises at least one resiliently flexible member (14) which is coupled to the support means and which is adapted for pressing, when in use, against the handle in order to keep it near the container when the container is placed in the operating mixing position.
Patent NZ-528851-A (NZ)
Title: N-aroyl cyclic amines
Inventor: BRANCH CLIVE LESLIE
IPC: A61K31/454
Filed: 2002-05-02
Abstract: Disclosed are compounds of formula (I), wherein: Y is a bond, oxygen or (CH2)n, wherein n is 1-3: R is H or alkyl, Ar1 is aryl, or a mono or bicyclic heteroaryl containing up to three heteroatoms selected from N, O and S, Ar2 is phenyl, or a 5 or 6-membered heterocyclyl group containing up to 3 heteroatoms selected from N, O and S, wherein the phenyl or heterocyclyl group is substituted by R1 and further optional substituents, or Ar2 is an optionally substituted bicyclic aromatic or bicyclic heteroaromatic group containing up to 3 heteroatoms selected from N, O and S. The compounds are used in the manufacture of medicaments for the treatment of obesity, including obesity in type 2 diabetes patients, and/or sleep disorders.
Patent NZ-529032-A (NZ)
Title: Substituted sulfonamide compounds, process for their use as medicament for the treatment of CNS disorders, obesity and type II diabetes
Inventor: BEIERLEIN KATARINA
IPC: A61K31/4965
Filed: 2002-06-11
Abstract: Disclosed is a substituted sulphonamide compound of the formula I wherein its substituents are as described in the specification, which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system.
Patent NZ-533700-A (NZ)
Title: Eplerenone crystalline form
Inventor: BARTON KATHLEEN P
Filed: 2000-12-04
Abstract: Disclosed is a composition comprising and a process for preparing a solvated crystalline form of eplerenone, wherein: the solvated crystalline form can be desolvated to yield Form L crystalline eplerenone characterised by an X-ray powder diffraction pattern at a wavelength of 1.54056 angstroms, and the solvated crystalline form is selected from methyl ethyl ketone, 1-propanol, 2-pentanone, acetic acid, acetone, butyl acetate, chloroform, isobutanol, ethanol, isobutyl acetate, methyl acetate, ethyl propionate, n-butanol, n-octanol, isopropanol, propyl acetate, propylene glycol, t-butanol, tetrahydrofuran, toluene, methanol, and t-butyl acetate solvates. The disclosed process is useful in the preparation of a pharmaceutical composition for the treatment or prevention of an aldosterone-mediated condition.
Patent NZ-534710-A (NZ)
Title: Disubstituted pyrazolyl carboxanilides
Inventor: DUNKEL RALF
IPC: C07D231/14
Filed: 2003-02-06
Abstract: A Pyrazolylcarboxanilide compound of Formula (I) is disclosed. This compound can be used for controlling unwanted microorganisms in crop protection and the protection of materials.
Patent NZ-535122-A (NZ)
Title: Gene and proteins, and their use
Inventor: HUGHES MARTIN JOHN GLENTON
IPC: A61K48/00
Filed: 1999-12-22
Abstract: A peptide comprises the sequence identified as SEQ ID NO:13 (pjo2-15) obtainable from Group B Streptococcus. The peptide or polynucleotide encoding it can be used in a pharmaceutical composition for treating bacterial infection.
Patent NZ-536079-A (NZ)
Title: Blanket
Inventor: SANDERS HANS-CHRISTIAN
IPC: A47G9/02
Filed: 2002-12-04
Abstract: Disclosed is a blanket (1) of the conventional type, particularly for beds, comprising at least one flexible layer (2) which is made of a light insulating material. The blanket is configured such that the flexible layer thereof keeps the occupant warm in bed. The aim is to improve humidity regulation and evacuate excess heat and the moisture given off by the body. This is achieved by providing the flexible layer with ventilating openings.
Patent NZ-537935-A (NZ)
Title: Antitumoral analogs of lamellarins as topoisomerase I inhibitors
Inventor: BAILLY CHRISTIAN
IPC: A61K31/4745
Filed: 2003-08-13
Abstract: Lamellarins representing a new series of topoisomerase I inhibitors is disclosed directed to compounds of the general formula III wherein its substituents are described in the specification. These compounds are used in the manufacture of a medicament to stimulate topoisomerase I-mediated DNA cleavage and their cytotoxic potential makes them useful as antitumor agents.
Patent NZ-538897-A (NZ)
Title: Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
Inventor: BIFTU TESFAYE
IPC: A61K31/55
Filed: 2003-10-14
Abstract: Beta-amino heterocyclic dipeptidyl peptidase inhibitors of formula (I) are disclosed, wherein the variables are as defined in the specification. These compounds of formula (I) are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes.
Patent NZ-540341-A (NZ)
Title: Papermaking roll cover and method for its production
Inventor: DAVENPORT FRANCIS L
IPC: D21F3/08
Filed: 2003-11-13
Abstract: The present invention is a method for making a roll cover and a roll cover, wherein at least one material is applied to the surface of the roll or a base substrate. In a first embodiment, a single material is applied as a flowable phase. A uniform coating of the material is applied to the roll, and upon setting of the material, such as by cooling, curing, or other means, a smooth and permanent roll cover is formed upon the surface of the roll. In another embodiment, at least two materials are applied in flowable phases to the surface of the roll. The first material may be a sacrificial, removable first material, applied to the surface of the roll cover in a preselected pattern. After the sacrificial material has been applied, a second material, such as a functional resin, is applied to the surface of the roll cover with the sacrificial material removed after the second material has set. In another embodiment, the use of sacrificial material is avoided and the material is applied in a predetermined pattern. In a fourth embodiment, two or more different materials are applied.
Patent NZ-540917-A (NZ)
Title: Sanitary outflow fitting
Inventor: GANZLE FRITZ
Filed: 2003-12-24
Abstract: The invention relates to a sanitary outflow fitting, especially a single-lever mixer (1), comprising, a housing (2) provided with at least one admission (5, 6) for water, and one outlet (49). A control cartridge (26) is located inside (10) the fitting housing (2), the manually operable control lever (34) of said cartridge controlling the flow of water through the outflow fitting (1). The aim of the invention is to be able to use a conventional control cartridge (26) with the admission and outflow openings thereof located on the lower side, even when the outflow (49) is in the upper or uppermost region of the outflow fitting (1). To this end, the control cartridge (26) is arranged inside a receiving insert (14). Water arriving towards the control cartridge (26) and leaving the same flows through said receiving insert (14). The water leaving the control cartridge reaches a water distribution chamber (12) which is provided between the receiving insert (14) and the bottom of the inner chamber (10) of the fitting housing (2), and guides the water into the radially outer region of the inner chamber of the fitting housing (2), whereupon it can flow towards the outflow (49), via a through-flow chamber (24) located between the envelope surface of the receiving insert (14) and the envelope surface of the inner chamber (10) of the fitting housing (2).
Patent NZ-541022-A (NZ)
Title: A milk conveyer device, with milking, sampling and analysis
Inventor: SANDBERG OLA
IPC: A01J7/02
Filed: 2003-12-19
Abstract: Disclosed is a milk conveyer device (100) for an animal. The milk conveyer device is to be implemented in a milking arrangement which comprises a milk storage reservoir (101) coupled to a milking attachment for attaching to an animal to be milked through a main milk conduit (103, 105). A sample element (109, 111) extracts milk, which is collected in a sample reservoir (115, 117) is connected to an analysis element (129) through an analysis conduit (123, 125). During the flow of the milk from the sample reservoir to the analysis element (129), the milk itself provides a cleaning effect. The flow is initially at a high flow rate and later at a reduced flow rate. A plurality of analysis conduits (123, 125) are connected to the analysis element (129), which comprises a selector unit (127), which couples milk from one of the analysis conduits (123, 125) to the analysis element (129). The device provides a self-cleaning effect and a low carry-over of milk between the two successive milking operations, i.e. between the milk of two different animals.
Patent NZ-546836-A (NZ)
Title: Liquid cleaning composition containing an anionic polyacrylamide copolymer
Inventor: MONDIN MYRIAM
IPC: C11D1/83
Filed: 2004-11-05
Abstract: Disclosed is a cleaning composition comprising approximately by weight: (a) 0.1 wt. % to 8 wt. % of an anionic surfactant selected from the group consisting of sulfonates surfactants and sulfated surfactants;(b) 0.025% to 2% of a sodium salt of an olefin maleic acid copolymer; and (c) 0.001 % to 0.5% of an anionic polyacrylamide copolymer; and (d) water. Another embodiment discloses a cleaning composition comprising approximately by weight: (a) 0.5% to 8% of an ethoxylated nonionic surfactant; (b) 0.025% to 2% of a sodium salt of an olefin maleic acid copolymer; (c) 0. 001 % to 0.5% of an anionic polyacrylamide copolymer; and (d) water. These cleaning compositions may further include fatty acids and perfumes.
Patent NZ-547415-A (NZ)
Title: Arrangement and method for feeding animals
Inventor: MAZERIS FERNANDO
IPC: A01K5/02
Filed: 2005-01-13
Abstract: A feeding device for feeding animals on a farm that includes an analyser, a feeder and a control device. The control device is configured to control the analyser to measure, at least once a day at least one constituent of the solid feed fed to the animals. The control device also controls the feeder such that the amount of feed the animals get depends on the earlier measured amounts.
Patent NZ-548921-A (NZ)
Title: Target for B-cell disorders
Inventor: DUNN ROSANNE DOROTHY
IPC: A61K39/395
Filed: 2005-02-28
Abstract: Provided is the use of an anti-LMA antibody in the manufacture of a medicament for the treatment or prophylaxis of a B-cell disorder in a subject, wherein an effective amount of the anti-LMA antibody is to be administered to the subject to inhibit the growth of, or kill, lymphoid cells in the subject. Further provided are such antibodies conjugated to toxins, chemotherapeutic agents or radioactive agents. Also provided is a similar use for autologous haematopoietic cell transplantation in a subject with B-cell disorder.
Patent NZ-555302-A (NZ)
Title: Post treatment of microfiltration membranes with hyfrogen peroxide and a transition metal catalyst
Inventor: MULLETTE DANIEL
IPC: B01D71/34
Filed: 2005-12-02
Abstract: Disclosed is a method of forming a functionalised polymeric hydrophilic microfiltration or ultrafiltration membrane with an increased permeability, which includes the steps of: (i) preparing a dope comprising a polymeric material and a cross-linkable component (such as poly(vinyl pyrrolidone), poly(vinyl acetate) or copolymers of vinyl pyrrolidone and vinyl acetate); (ii) preparing a polymeric microfiltration or ultrafiltration membrane from the dope; and (iii) treating said polymeric microfiltration or ultrafiltration membrane with a hydroxyl radical generated by an aqueous solution of a transition metal catalyst (such as iron, molybdenum, chromium or cobalt) in conjunction with hydrogen peroxide to cross-link said crosslinkable component.
Patent NZ-560789-A (NZ)
Title: Dipeptidyl peptidase-IV (DPP-IV) inhibiting compounds, methods of preparing the same, and pharmaceutical compositions containing the same as an active agent
Inventor: LEE CHANG-SEOK
IPC: C07D471/04
Filed: 2006-03-30
Abstract: Disclosed are Dipeptidyl Peptidase-iv inhibiting compounds of formula 1 wherein "A" is selected from formulas 2-7 and "B" is selected from formulas 8-11 as described in the specification and pharmaceutical compositions containing the same as an active agent.
Patent NZ-560792-A (NZ)
Title: Methods of administering anti-TNF alpha antibodies
Inventor: KEMPENI JOACHIM
IPC: A61P3/10
Filed: 2002-06-05
Abstract: Disclosed is the use of an anti-TNFalpha antibody, or an antigen binding portion thereof, in the manufacture of a medicament for inhibiting human TNFalpha activity in a human subject suffering from a disorder in which TNFalpha activity is implicated, wherein the medicament is adapted for biweekly administration as a total body dose, and wherein the disorder is an intestinal disorder.
Patent NZ-561596-A (NZ)
Title: Improvements in/or relating to a waste outlet
Inventor: KNIGHT RODNEY PAUL
Filed: 2007-09-17
Abstract: A waste, typically a shower waste, comprises an outer housing with an outlet at a lower part thereof, fixing means to secure the outer housing in an opening, and an inner conduit having a lower end positioned or positionable in the housing and an upper end having an upper edge or flange, the upper edge or flange having one or more slots or grooves therein, the slots or grooves being able in use to take water to be drained therethrough, the water then passing down through said inner conduit to the outlet of the housing.
Patent NZ-563551-A (NZ)
Title: Lift installation, a guide rail of a lift installation, brake equipment of a lift installation and a method for guiding, holding and braking a lift installation
Inventor: KOCHER HANS
Filed: 2007-11-20
Abstract: Brake equipment that can hold a lift cage at standstill with low actuating force, while also being in a position to provide emergency braking of the lift cage, is disclosed. A brake lining (12) co-operates with a brake surface (11), where the brake surface has at least one longitudinal wedge groove or wedge elevation which is oriented in the braking direction.
Patent NZ-567477-A (NZ)
Title: A scraped surface heat exchanger and a method for producing whey protein concentrate
Inventor: THORSEN KNUD
IPC: A01J25/06
Filed: 2006-10-04
Abstract: A scraped surface heat exchanger 100 comprises a heat exchanging wall 20 with a cylindrical inner surface 21 with a radius (R + 0), a rotatable shaft 10 mounted inside of and concentric with the inner surface 21 of the heat exchanging wall 20, and a scraping member 40 supported by the shaft 10 and extending to the inner surface 21 of the heat exchanger wall 20. The shaft 10 has a gap portion with an outer surface 11 and a radius R, which extends over at least 60% of its circumference. The scraping member 40 is adapted to exert a shear rate (D = 1/30*pi*n*R/sigma) less than 600/s.
Patent NZ-569481-A (NZ)
Title: Adjustable bone plate
Inventor: RALPH JAMES D
IPC: A61B17/58
Filed: 2006-12-20
Abstract: A bone plate has at least one set of first and second members 501 and 502. The first members 501 have integral flanges 8 extending from an end and the second members 502 have recesses 59 extending from the top surface of the member to a bottom surface of the recess and shaped complimentarily to the shape of the flange so as to permit the flange to slide snugly in the recess and to be fitted into the recess either from the open end of the recess or the open top of the recess in order to attach the first member to the second member. The length of the assembled plate can be altered by loosening the locking screw 94, allowing the flange to slide within the recess, then tightening the locking screw when the correct length is established.