baber/WOPTO huggingface dataset:
Patent DO-P2015000042-A (DO)
Title: Formulación de una cápsula farmacéutica compuesta que comprende irbesartan e inhibidor de la hmg-coa reductasa
Inventor: PARK JAE HYUN
IPC: A61K31/41
Filed: 2015-02-26
Abstract: Se divulgan una formulación de una cápsula farmacéutica compuesta que comprende 1) una unidad de irbesartan independiente que comprende irbesartan o una de sus sales aceptables desde el punto de vista farmacéutico; y 2) una unidad independiente de inhibidor de la HMG-CoA reductasa que comprende un inhibidor de la HMG-CoA reductasa o una de sus sales aceptables desde el punto de vista farmacéutico, y un aditivo alcalino, en donde dichas unidades independientes se separan unas de otras dentro de una cápsula, y un método para preparar la misma. Diseñada para prevenir una interacción entre irbesartan y el inhibidor de la HMG-CoA reductasa, la formulación de una cápsula farmacéutica compuesta es mejorada en estabilidad y velocidad de disolución, y de este modo muestra gran biodisponibilidad. Además, se espera que la formulación garantice un alto cumplimiento del medicamento debido a su pequeño tamaño, y por lo tanto puede aplicarse al tratamiento de la hipertensión e hipercolesterolemia.
Patent DO-P2015000270-A (DO)
Title: Potenciador de inhibidores del homólogo de zeste
Inventor: SU DAI-SHI
IPC: C07D413/14
Filed: 2015-10-30
Abstract: ESTA INVENCIÓN SE REFIERE A COMPUESTOS NOVEDOSOS DE ACUERDO CON LA FÓRMULA (I) QUE SON INHIBIDORES DEL POTENCIADOR DE HOMÓLOGO ZESTE 2 (EZH2), A COMPOSICIONES FARMACÉUTICAS QUE LOS CONTIENEN, A PROCEDIMIENTOS PARA SU PREPARACIÓN Y A SU USO EN TERAPIA PARA EL TRATAMIENTO DE CÁNCERES. FORMULA I
Patent EE-200400052-A (EE)
Inventor: BROECKX RUDY LAURENT MARIA
IPC: B01D11/02
Filed: 2002-07-09
Abstract: The present invention relates to an improved process for the preparation of proton pump inhibitors of the benzimidazole-type such as rabeprazole, omeprazole, pantoprazole, lansoprazole and esome prazole, of general formula (1) by oxidation of the corresponding sulfide followed by extraction of the sulfone by-product with an aqueous alkaline solution at controlled pH.
Patent GB-189704338-A (GB)
Title: Improved Water Wheel or Wind Motor Apparatus.
Inventor: KERSTEN WILLIAM EARNEST
Filed: 1897-02-17
Granted: 1897-03-20
Abstract: 4338. Kersten, W. E. Feb. 17. Locomotives.-Relates to apparatus for utilizing the current of a stream for transporting loads in the opposite direction. The same principle may also be applied in the case of wind motors. The bucket-wheel W, dipping into the stream, is rotated in the direction of the curved arrow. Wheels R, mounted on the axle A of the bucket-wheel, travel on rails S arranged on both sides of the stream, so that as the bucket-wheel rotates it travels in the opposite direction to that of the stream and takes with it the load requiring transportation. In the case of steep inclines the wheels R may be toothed, as shown in Fig. 1, and the rails S may be in the form of racks.
Patent GB-189706584-A (GB)
Title: Improvements in Automatic Grease Boxes.
Inventor: WALCH GUSTAV
Filed: 1897-03-12
Granted: 1897-04-17
Abstract: 6584. Walch, G. March 12. Lubricators for pistons, axles, shafts, &c. Grease is expressed from the cup a by the piston b operated by the screw c driven by clockwork. The spring barrel g is connected by gear-wheels f, e, d with the screw c, and also by a train with a balancewheel p. This balance-wheel, which is shown in Fig. 4, is supported on adjustable bearing-pieces q perforated to preserve the pivots and to hold lubricating oil. The action of the clockwork may be stopped by moving the knob n so as to bring the rod o in contact with the balance-wheel. The piston may be moved by the handle h, the stem i of which can be lifted to disengage the pinion f from the spring barrel without disengaging the longer pinion e from the wheel d.
Patent GB-189708725-A (GB)
Title: Art of and Apparatus for Generating and Distributing Music Electrically.
Inventor: SLOAN ROBERT ALEXANDER
Filed: 1897-04-06
Granted: 1897-08-21
Abstract: 8725. Sloan, R. A., [Cahill, T.]. April 6. Drawings to Specification. Telephones.-In apparatus for generating and distributing music electrically, electrical pulsations are produced by making and breaking circuits, and these pulsations are rendered as musical sounds by a special form of telephone or vibrationtranslating device. The device consists of a soundboard, a number of soft iron armatures attached to the board, a number of cores and magnetizing coils opposite to the armatures, and coils of fine wire wound round the ends of the cores which pull upon the armatures.
Patent GB-189710021-A (GB)
Title: Improvements relating to Pivotted Window Sashes.
Inventor: MAKINSON JOSEPH
Filed: 1897-04-22
Granted: 1898-02-26
Abstract: 10,021. Makinson, J. April 22. Windows.-The sash is mounted on central vertical pivots a, b, and can be held in any required position by a pivoted catch s arranged to enter a perforated sector r fixed to the sill. The upper pivot is fixed to the top rail c of the sash and enters a socket d in the frame. The lower pivot is fixed to the sash, and the socket consists of two parts f, g. One half f is fixed to the sash rail, and the other half g is hinged to turn back to allow the sash to be taken out of the frame and is secured by a screw. Draught-excluding strips n, o at the top and bottom rails of the sash enter grooves in the window head and sill, and the sash stiles are rabbeted to engage with ribs or beads of the frame.
Patent GB-189711228-A (GB)
Title: The Production of Sterile Iodoform.
Inventor: ZIMMERMANN AUGUST
Filed: 1897-05-05
Granted: 1898-04-02
Abstract: 11,228. Zimmermann, A., [Chemische Fabrik auf Actien vorm. E. Schering]. May 5. Antiseptics.-Iodoform, which is in a sterile condition and automatically re-sterilizes itself in face of infection, is produced by mixing iodoform with 0À05 to 0À25 per cent. of polymerized formaldehyde, such as paraformaldehyde, alpha-trioxymethylene, or the like. A polymeric compound suitable for the purpose is prepared by mixing 40 per cent. formaldehyde solution with concentrated sulphuric acid whilst cooling, and then allowing the mixture to stand for several days. The white powder which is precipitated is sucked off, washed with water, and dried at the usual temperature. The preparation of iodoform above described is characterised by anti-bacterial properties, due to a slow development of formaldehyde, the odour of which is apparent even after exposure of the substance to the air for several days.
Patent GB-189716561-A (GB)
Title: Prismatic Window Lights with one Surface of Each Prism Curved.
Inventor: EWEN JOHN MEIGGS
Filed: 1897-07-13
Granted: 1897-08-21
Abstract: 16,561. Ewen, J. M. July 13. Windows.-The lower surface of the prism shown in Fig. 3 is curved in such a manner that equal areas L<1>, L<2>, L<3>, L<4>, L<5> taken at right-angles to the rays of light, and at different distances along a horizontal line, are illuminated to the same extent. By varying the curvature, the light can be directed to illuminate horizontal areas equally. Fig. 2 shows a form of prism adapted to direct the rays of light horizontally.
Patent GB-189718235-A (GB)
Title: Improvements in connection with Arc Lamps.
Inventor: JONES WALTER JOHN HUBERT
Filed: 1897-08-05
Granted: 1898-06-25
Abstract: 18,235. Jones, W. J. H., Chaplin, F. J., and Jevons, S. Aug. 5. Arc lamps.-Regulating-mechanism for a focussing-lamp is constructed as shown in Fig. 1. The carbon-holders are carried by the ends of two cords passed over pulleys e<2>, e<3>, e<5>, e<6> in stationary bearings ; the pulleys e<2>, supporting the parts of the cords attached to the upper holder, are carried by a spindle E on antifriction wheels J, J<1>. Horizontal series and shunt solenoids, one of which is shown at A, are placed at the sides of the pulleys, and act on cores attached to the ends of a horizontal lever B. This is connected by a link D to a lever having two arms d<2> with V-grooves, which engage and lift the spindle E from the antifriction wheels J, J', when the action of the series coil preponderates, to strike the arc. For feeding the carbons, the shunt coil causes the lever d<2> to lower the spindle E upon the antifriction wheels, so that it can rotate. Fig. 3 shows a modification, in which the upper carbon is carried by a rack S in engagement with a pinion on the spindle p<1>, which carries two flanged wheels P, and can rotate in bearings p<2>. A series or differentially wound coil A acts through a core k<1> and slotted levers K on rotatable discs M ; these carry a pin m<1>, operating a lever N and brake blocks n<3> to lift the flanged wheels P with the spindle p', rack S, and upper carbon, to strike the arc, when the action of the series coil is sufficient. For feeding the carbon, the brake n<3> allows the wheels and spindle to rotate in the bearings p<2>. The lower carbon may be fixed, or connected by cords and pulleys with the upper one.
Patent GB-189720571-A (GB)
Title: Process and Apparatus for the Production of Carburetted Air for Incandescent Gas Light.
Inventor: KAHNS OSCAR
Filed: 1897-09-07
Granted: 1897-10-09
Abstract: 20,571. Kahns, O. Sept. 7. Incandescent lamps consuming carburetted air. A current of air becomes charged with hydrocarbon vapour in traversing a box or chamber c containing a cheap product of petroleum refining and a number of wick-like partitions b of absorbent woollen or other fabric.
Patent GB-189723449-A (GB)
Title: Improvements in and relating to Railway and like Vehicles.
Inventor: PECKHAM EDGAR
Filed: 1897-10-12
Granted: 1898-02-05
Abstract: 23,449. Peckham, E. Oct. 12. Axle-trucks; springs, bearing.-The pedestals 8 are connected by the beams 11, 12, and carry bolts 19 for connecting the sill 7 to each lower beam 18. The sill is supported near the pedestals by springs 17, 14, and at its ends by springs 22 and by leaf or partial elliptic springs 15, each of which is carried by brackets 23, 24 on the extended beams 13. Truss beams 16 connect the beams 13 to the beams 18. The springs 22 are carried by brackets 21, which can slide vertically in the brackets 24. The cross-bars 28 are stiffened at their middle by plates 30 where they receive the noses of the motors, and the cross-bars are carried at their bifurcated ends by springs 27, which are separated by the ends of the brackets 26a on the cross-rods 26. Bra7ces.-The ends of the brake beams 31 are twisted so as to slide in inclined grooves in brackets 33 on the car. The brakes are, therefore, normally held off by gravity, such movement of the brake beams in their grooves being assisted by springs.
Patent GB-189724139-A (GB)
Title: An Improvement in the Manufacture of Bricks for Fixing Purposes.
Inventor: JARVIS WILLIAM GEORGE
Filed: 1897-10-19
Granted: 1898-01-01
Abstract: 24,139. Jarvis, W. G. Oct. 19. Bricks for facing purposes are made from a mixture of equal quantities of clay or brick earth and sawdust, to which cinder, ash, or coal dust may be added. Such bricks afford a good hold to mortar and plaster, and may be used as facing-bricks.
Patent GB-189800317-A (GB)
Title: Improvements in or relating to Water Valves and the like.
Inventor: JONES JOHN
Filed: 1898-01-05
Granted: 1898-11-19
Abstract: 317. Jones, J. Jan. 5. Diaphragm valves for cisterns and the like. To ensure that the central portion of the diaphragm G shall follow the plunger H and not adhere to the end of the supply pipe E when the plunger H recedes therefrom, the central portion of the diaphragm may be secured to the plunger by a screw, as shown at I, Fig. 3, or the plunger H may, as shown in Fig. 1, pass through the centre of the diaphragm, a flange or collar H<3> being provided to secure the diaphragm and also the facing H<2>, when the latter is used. The actuating-lever J engages with a slot L in the end of the plunger H.
Patent GB-189800524-A (GB)
Title: Improvements in and relating to Reflecting Devices for Lamps.
Inventor: SAUVALLE MAURICE
Filed: 1898-01-07
Granted: 1898-12-10
Abstract: 524. Sauvalle, M. Jan. 7. Reflectors.-Multiple reflecting-surfaces and non- reflecting, translucent, or transparent surfaces or free spaces are grouped around a luminous source, the form and position of these surfaces being so arranged as to receive the rays near the source and reflect them in definite directions. Fig. 1 shows an incandescent electric lamp globe having annular reflecting-surfaces B ... B<3> and transparent surfaces C ... C<3>. In other forms, translucent reflecting-surfaces are used. Annular reflecting-surfaces are in some cases fused externally to the globe or bulb or to a non-adherent envelope which may be partly reflected and partially covers the globe; in one form, this envelope consists of concave and convex reflecting- rings. Fig. 12 shows the device applied to the globe of an incandescent gas &c. burner. A series of reflecting-surfaces B ... B' are fused to a transparent envelope H, H<1>, H', or the reflecting- surfaces may be fused to a transparent chimney or truncated cone. Fig. 17 shows a modification having a reflecting-dome b, transparent portions H ... H<4> and reflecting-portions B ... B<4>. In street and like lamps the reflecting-surfaces may be secured to the inside of the transparent walls.
Patent GB-189802480-A (GB)
Title: Improvements in the Manufacture or Production Simultaneously of Pure Ortho-nitro-chloro-benzene and Pure Para-nitro-chlorobenzene.
Inventor: JOHNSON GEORGE WILLIAM
Filed: 1898-01-31
Granted: 1898-03-26
Abstract: 2480. Johnson, G. W., [Chemische Fabrik Griesheim]. Jan. 31. O-and p-nitrochlorobenzene, which are found to differ in boiling point by 6‹-7‹ C., are produced separately in a pure state from the mixture thereof remaining from the manufacture of p-nitrochlorobenzene. The mixture is first fractionally distilled under atmospheric or reduced pressure. The pure para compound is then precipitated from the first fractions, and the pure ortho compound from the last fractions, by fractional crystallization. By repeatedly subjecting the mother liquors to fractional distillation and fractional crystallization, the two substances are ultimately completely separated in the pure state.
Patent GB-189803879-A (GB)
Title: Improvements in Brakes for Cycles.
Inventor: WILLIAMS ALBERT
Filed: 1898-02-16
Granted: 1898-04-16
Abstract: 3879. Williams, A. Feb. 16. Brakes operated by foot-levers. Fig. 1 shows the invention as applied to a safety bicycle, but it may be applied to ladies' bicycles or other cycles. A brake shoe is carried by a link D pivoted to a clamp B fixed to the diagonal tube C. A foot-lever A, a<1> pivoted to the clamp at a takes beneath the link D, so that when the foot-lever is depressed the brake is applied. A spring arranged between pins f, a<2> on the clamp B and foot-lever respectively keeps the foot-lever in its normal position.
Patent GB-189804628-A (GB)
Title: Process for the Manufacture of a New Refractory Material.
Inventor: IMSCHENETZKY ALEXANDER
Filed: 1898-02-24
Granted: 1899-04-24
Abstract: 4628. Imschenetzky, A. Feb. 24. Stone, artificial ; refractory substances.-Relates to improvements in the process for the manufacture of artificial stone, described in Specification No. 5254, A.D. 1895. Asbestos fibres are separated and kneaded with water into a paste which is mixed with carbonates or oxides of calcium, magnesium, iron, &c. to cheapen the product or to vary its specific gravity or colour. The paste is made into sheets or into objects of any desired form which are dried, cemented with a solution of silica as in the earlier process, pressed, and again dried. They are then impregnated first with a strong solution of sodium silicate and afterwards with a saturated solution of sodium bicarbonate. Silica is formed in the pores of the material and the bicarbonate is converted into carbonate of soda. The process may be repeated, and ammonium or potassium salts may be substituted for the sodium salts described. The silicate and bicarbonate may be mixed, and the material saturated with the solution before the silica has gelatinized. A solution of carbon dioxide under pressure may be used in place of the bicarbonate. Objects made of the material may be coated with mineral pigments mixed with silicate, and treated after drying with calcium or magnesium chloride.
Patent GB-189809039-A (GB)
Title: Improved Method of Strengthening Copper Pipes.
Inventor: MESSENGER THOMAS
Filed: 1898-04-19
Granted: 1899-02-04
Abstract: 9039. Messenger, T. April 19. Metal pipes and tubes.-Relates to a method of strengthening copper tubes, especially brazed copper steam pipes for boilers, by wrapping them with wrought-iron or other metal bands. The copper pipe is encircled at intervals by metal bands B, C, the ends of which are formed with tongues b, c or forks b<1>, c<1>, and which are secured by cottar pins d or other means. Where bends occur in the copper tube, the bands C are of round cross-section.
Patent GB-189812589-A (GB)
Title: Improvements in Guards for Coin Controlled Apparatus.
Inventor: MAYER CHARLES PETTER
Filed: 1898-06-04
Granted: 1898-07-09
Abstract: 12,589. Mayer, C. P. June 4. Coin action.-Within a drum casing A a slit post 11 separates a shaft 3 bearing a toothed wheel 10 and a handle 1 bearing a disc 6 upon which is mounted a pair of contiguous plates 14, forming with the post a radial pocket c. A coin thrust into the pocket makes a latch 18 therein engage the wheel 10 so that it turns with the handle, till the coin drops through the post. Coin - slit closing - devices.-The coin is put into the pocket at an aperture 25 in the front 2 of the casing. A door 27 on a hinge 28 normally closes the aperture. Fraud, preventing.-When the door is opened to insert a coin, a cam 30 forming a continuation of its handle 29 engages a slot in the rotary disc so that this is locked and also slightly turned. When the door is closed after the insertion of a coin, a torsional stress is put on the engaged latch till the disc is free, whereupon a jump occurs which displaces the slot'in the disc from the cam of the door so that the latter cannot be again opened till the actuation has occurred.
Patent GB-189814191-A (GB)
Title: Improvements in Incandescence Baskets.
Inventor: IMRAY JOHN
Filed: 1898-06-27
Granted: 1899-05-27
Abstract: 14,191. Imray, J., [Moeller, J.]. June 27. Incandescent gas &c. lamps.-Relates to means for producing porous mantles or baskets of the Clamond type, which are made by weaving or netting together threads of refractory material produced by squeezing a paste of magnesia or the like through a die. Cotton, pith, or other substance possessing cellular structure is impregnated with a solution of a salt of the refractory earth, incinerated, and reduced to a fine powder by rubbing through a fine sieve with a brush. The paste formed by mixing this powder with an agglutinating-substance, such as starch, or a mixture of starch and gluten or gelatine or wheat flour with a solution of the refractory earth, is squeezed through a die to form the flexible threads from which the mantles are woven or netted. After the mantles have been heated in a closed chamber or a reducing-medium to carbonize the organic ingredients, they are baked at a high temperature in an oxidizing medium or flame before use.
Patent GB-189819103-A (GB)
Title: Manufacture of a New Chloral Combinations.
Inventor: BOULT ALFRED JULIUS
Filed: 1898-09-07
Granted: 1899-07-15
Abstract: 19,103. Boult, A. J., [Wagnitz, R.]. Sept. 7. Disinfectants.-Chloral compounds which have extraordinary disinfecting properties are produced by the following processes : (1) Boracic acid, milk sugar, or salicylic acid is dissolved in dry glycerine, the mixture is heated until all water present has been expelled, and, after cooling the mixture to about 40‹ C., chloral is vigorously stirred in. Heat is developed during these mixing operations, and the product is a clear, thick, non-volatile liquid soluble in water. (2) An alcohol of the terpene series, such as menthol or terpineol, is acted upon by bromide or iodine, and the resulting compound is treated with chloral, in which operation much heat is evolved. The product is very volatile and is soluble in alcohol. The Provisional Specification relates also to a chloral-phenol-menthol compound. (3) The chloral compounds above described are converted into powders by mixing them with magnesium hydrate, or magnesium hydrocarbonate, with which they form stable chemical combinations.
Patent GB-189819497-A (GB)
Title: A New and Improved Method of Uniting Articles made of Glass.
Inventor: DUKES THOMAS
Filed: 1898-09-14
Granted: 1899-09-09
Abstract: 19,497. Dukes, T. Sept. 14. Flower vases and like receptacles. - Flower vases or other fancy articles made of glass in two or more parts are provided with screw fittings A, B, formed on the glass itself so so as to render the use of brass or other metal fittings unnecessary.
Patent GB-189820227-A (GB)
Title: Improvements in Electric Lamp Holders
Inventor: WATSON ALFRED
Filed: 1898-09-24
Granted: 1899-07-29
Abstract: 20,227. Watson, A. Sept. 24. Incandescent lamps, holders for. Connection is made between the supply wires and the contactplates of capped lamps by short flexible conductors d, the free ends d<2> of which are held against the contact-plates by spring plungers f, e, or equivalent means. The invention is a modification of that described in Specification No. 27,482, A.D. 1896. In the form shown in section, the springs f and flexible conductors d bear against plates b, which are held in separate recesses in an insulator a by blocks c<1>, provided with lateral binding - screws below the insulator to hold the supply wires. The flexible conductors d may, if desired, be held in direct contact with the supply wires.
Patent GB-189901178-A (GB)
Title: An Improved Method of Attaching Door and other Knobs to Spindles and the like.
Inventor: ASHWORTH ABRAHAM
Filed: 1899-01-18
Granted: 1899-11-11
Abstract: 1178. Ashworth, A. Jan. 18. Drawings to Specification. Knobs, attaching.-A door or other knob is attached to its spindle or the like by a screw passing axially through the knob into the spindle. A screw socket passing over the spindle may be used instead, and may be locked by a screw passing into the spindle.
Patent GB-189905993-A (GB)
Title: Improvements in Tyres.
Inventor: POIZOT EMILE
Filed: 1899-03-20
Granted: 1900-02-17
Abstract: 5993. Poizot, E. March 20. Tyres, elastic other than pneumatic.-The rubber tyre A is enclosed in an outercoverBof helicallywound cord formed from leather, catgut, or, preferably, textile fibre, woven or strongly twisted. The cord is impregnated with a mixture consisting of rubber solution and gum, glue, or the like. The helical winding may be replaced by rings jointed together.
Patent GB-189906149-A (GB)
Title: Improvements in the Manufacture of Filaments for Incandescing Electric Lamps, and in Means applicable for Use in such Manufacture.
Inventor: VOELKER WILLIAM LAWRENCE
Filed: 1899-03-21
Granted: 1900-02-10
Abstract: 6149. Voelker, W. L. March 21. Mills.-Pure carbides of titanium, uranium, and thorium, for use in electric lamp filaments, are ground to impalpable powder under benzene or naphtha in a mill provided with grinding- surfaces a, b, made of the carbide. The mill is enclosed in a casing having a plug h for the introduction of the liquid, which is removed with the carbide powder through a valve g. The shaft c is passed through a stuffing-box d, and rotated by worm gearing f.