baber/WOPTO huggingface dataset:
Patent BR-112022003546-A2 (BR)
Title: Método de isolar nucleossomos circulantes
Inventor: JACOB VINCENT MICALLEF
IPC: G01N33/68
Filed: 2020-08-27
Abstract: método de isolar nucleossomos circulantes. a presente invenção refere-se a métodos para separar nucleossomos livres de células circulantes compreendendo dna ligante a partir de uma amostra de fluido biológico, em particular, nucleossomos de origem de doença. tais métodos permitem uma melhor análise de marcadores genéticos epigenéticos associados a nucleossomos de origem de doença.
Patent BR-112022003882-A2 (BR)
Title: Composição farmacêutica para tratamento ou prevenção de câncer
Inventor: JOONG MYUNG CHO
IPC: A61P35/00
Filed: 2020-07-30
Abstract: composição farmacêutica para tratamento ou prevenção de câncer. a presente invenção se refere a um método para matar células cancerosas usando uma combinação de um inibidor de hdac e um anticorpo anti-pd-1 ou um anticorpo anti-pd-l1. a presente invenção pode ter uma influência efetiva em: prolongar a sobrevida de animais com câncer, tumores, distúrbios relacionados a tumores e doenças neoplásicas; inibir o crescimento de células proliferativas associadas a neoplasias; ou degeneração neoplásica.
Patent BR-112022006877-A2 (BR)
Title: Método para prevenir danos causados por radiação nas glândulas humanas
Inventor: JÖRG MÜLLER
IPC: A61K38/48
Filed: 2020-10-12
Abstract: MÉTODO PARA PREVENIR DANOS CAUSADOS POR RADIAÇÃO NAS GLÂNDULAS HUMANAS. A invenção se refere ao campo da oncologia por radiação. De acordo com a invenção, o método compreende o uso de toxina botulínica e um anticolinérgico para prevenir danos por radiação nas glândulas e efeitos colaterais causados por radioligantes. De acordo com a invenção, o método compreende ainda o uso de toxina botulínica para prevenir danos por radiação nas glândulas, em que os danos por radiação são causados por radioligantes. Ao usar o método de acordo com a invenção, a presente invenção pode proporcionar proteção eficaz das glândulas, a fim de evitar danos por radiação.
Patent BR-112022010822-A2 (BR)
Title: Métodos para cultivar células, preparação de hidrolisado a partir de células e aplicações dos mesmos
Inventor: PO SAN MARIO CHIN
IPC: A61P17/02
Filed: 2020-11-14
Abstract: MÉTODOS PARA CULTIVAR CÉLULAS, PREPARAÇÃO DE HIDROLISADO A PARTIR DE CÉLULAS E APLICAÇÕES DOS MESMOS. Trata-se de um método para gerar hidrolisado de células por cultura de células in vitro que inclui as etapas de lisar uma célula usando-se sonicação para liberar proteínas na célula; digerir as proteínas usando-se protease para produzir peptídeos curtos com um tamanho molecular menor que 500 dáltons (Da); terminar a etapa de digestão aquecendo-se a protease a uma temperatura predeterminada por um período de tempo predeterminado ou diluindo-se a protease a uma concentração predeterminada e filtrar de forma estéril a mistura da etapa de terminação de digestão através de um filtro de membrana. O hidrolisado de células gerado pode ser usado em vários produtos incluindo, porém sem limitação, cuidados com a pele, cuidados com ferimentos, cosméticos, produtos alimentícios, suplementos, fármacos e outras aplicações medicinais.
Patent BR-112022013130-A2 (BR)
Title: Sistemas e métodos para projeto e configuração de sinalização de referência em redes de comunicação sem fio
Inventor: ZHEN HE
IPC: H04L5/00
Filed: 2020-01-21
Abstract: SISTEMAS E MÉTODOS PARA PROJETO E CONFIGURAÇÃO DE SINALIZAÇÃO DE REFERÊNCIA EM REDES DE COMUNICAÇÃO SEM FIO. Sistemas e métodos para projeto e configuração de sinalização de referência em redes de comunicação sem fio são discutidos neste documento. Em uma modalidade, os sistemas e métodos são configurados para determinar, por um dispositivo de comunicação sem fio, um estado de feixe ativado aplicável a um sinal de enlace descendente recebido de um nó de comunicação sem fio. Os sistemas e métodos podem ser configurados adicionalmente para determinar, pelo dispositivo de comunicação sem fio com base pelo menos no estado de feixe ativado, uma primeira informação de um sinal de enlace ascendente para o nó de comunicação sem fio, o sinal de enlace ascendente associado a um recurso de enlace ascendente.
Patent BR-112022016385-A2 (BR)
Title: Processo hidrometalúrgico para extração simultânea de metais e gesso de pó de forno de arco elétrico em siderúrgicas
Inventor: JULIO DOMINGO BONELLI ARENAS
IPC: C22B19/30
Filed: 2021-02-09
Abstract: PROCESSO HIDROMETALÚRGICO PARA EXTRAÇÃO SIMULTÂNEA DE METAIS E GESSO DE PÓ DE FORNO DE ARCO ELÉTRICO EM SIDERÚRGICAS. Trata-se de um novo processo hidrometalúrgico para extração simultânea de zinco, chumbo, prata, ferro e cálcio de pó de forno de arco elétrico (resíduos perigosos) produzidos pela indústria siderúrgica (aciaria), na forma de produtos industriais: zinco como sulfato de zinco ou cátodos de zinco; chumbo e prata como concentrado de chumbo e prata; ferro como ferro elementar reduzido para retorno ao forno de arco elétrico; e, por último, o cálcio como gesso, sem geração de resíduos sólidos ou efluentes líquidos. Durante o processo ocorre a mudança na natureza química dos pós do forno de arco elétrico (óxidos complexos) em um complexo de sulfeto e elimina-se os riscos associados à geração de sais de metais pesados fugitivos. Além disso, o problema hidrometalúrgico de baixa recuperação de zinco e ferro é resolvido. Consequentemente, a hidrometalurgia se torna mais fácil e ecologicamente correta, pois a água condensada é utilizada como lixiviante, e é continuamente regenerada pelos sistemas de evaporação a vácuo sem gerar efluentes.
Patent BR-112023000685-A2 (BR)
Title: Transição de estado em sistemas de retransmissão da camada 2 de sidelink
Inventor: PENG CHENG
IPC: H04W76/27
Filed: 2020-07-25
Abstract: TRANSIÇÃO DE ESTADO EM SISTEMAS DE RETRANSMISSÃO DA CAMADA 2 DE SIDELINK. A presente invenção refere-se, em alguns aspectos, a técnicas para paginação em cenários de retransmissão da L2 de sidelink. Um método exemplificativo geralmente inclui receber, de um dentre uma entidade de rede e um UE de retransmissão ao qual o UE remoto está conectado, uma indicação de transição de um estado conectado para um estado ocioso ou inativo; e fazer a transição para um estado ocioso ou inativo em resposta ao recebimento da indicação.
Patent BR-112023019182-A2 (BR)
Title: Uso de um inibidor de citidina desaminase na preparação de um medicamento, sistema, kit ou artigo de manufatura e composição
Inventor: BABAL K JHA
IPC: A61K31/14
Filed: 2022-03-22
Abstract: uso de um inibidor de citidina desaminase na preparação de um medicamento, sistema, kit ou artigo de manufatura e composição. a presente invenção fornece composições, sistemas, kits e métodos para tratar um indivíduo com uma infecção por vírus de rna (por exemplo, sars-cov-2) administrando ou fornecendo uma composição que compreende um inibidor de citidina desaminase (por exemplo, tetra-hidrouridina ou cedazuridina).
Patent CZ-3597-A3 (CZ)
Title: Process for preparing trihydrate of (2r,3s)-4-acetoxy-2alpha-benzoyl-oxy-5beta,20-epoxy-1,7beta,10beta-trihyd roxy-9-oxo-tax-11-ene-13alpha-yl-3-tert-butoxycarbonylamino-2-hydroxy-3- -phenylpropionate
Inventor: AUTHELIN JEAN-RENE
IPC: C07D305/14
Filed: 1995-07-07
Abstract: PCT No. PCT/FR95/00910 Sec. 371 Date Apr. 25, 1997 Sec. 102(e) Date Apr. 25, 1997 PCT Filed Jul. 7, 1995 PCT Pub. No. WO96/01815 PCT Pub. Date Jan. 25, 1996Process for the preparation of 4-acetoxy-2 alpha -benzoyloxy-5 beta ,20-epoxy-1,7 beta , 10 beta -trihydroxy-9-oxo-tax-11-en-13 alpha -yl (2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionate trihydrate, characterized in that the 4-acetoxy-2 alpha -benzoyloxy-5 beta ,20-epoxy-1,7 beta ,10 beta -trihydroxy-9-oxo-tax-11-en-13 alpha -yl (2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionate is crystallized from a mixture of water and an aliphatic alcohol containing 1 to 3 carbon atoms, and then the product obtained is dried under defined conditions of temperature, pressure and humidity.
Patent CZ-33292-A3 (CZ)
Title: In ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalene and 3-aminochromate, process of their preparation and a pharmaceutical preparation comprising thereof
Inventor: HOECHSTETTER CRAIG STEVEN
IPC: A61P25/26
Filed: 1992-02-05
Abstract: Isoxazole derivs. of formula (I) and their acid-addn. salts and solvates are new: In (I) R = 1-4C alkyl, allyl or cyclopropylmethyl; R1 = H, 1-4C alkyl, allyl, cyclopropylmethyl or aryl(1-4C)alkyl; X = CH2 or O; y = 4-R2-5-R3-3-isoxazolyl or 3-R2-4-R3-5-isoxazolyl; R2 and R3 = H, 1-4C alkyl, 1-4C alkoxy, 1-4C alkylthio, OH, NH2, CN or Ph. Pref. x = CH2; R and R1 = 1-4C alkyl, esp. n-Pr; R2 and R3 = H.
Patent CZ-59199-A3 (CZ)
Title: INHIBITION METHOD OF FaS EXPRESSION
Inventor: FEUERSTEIN GIORA ZEEV
IPC: C07D209/88
Filed: 1997-08-22
Abstract: The present invention provides a method for inhibiting the expression of Fas which comprises administering to a mammal in need thereof an effective amount of a compound which is a dual non-selective  beta -adrenoceptor and  alpha 1-adrenoceptor antagonist.
Patent SK-20696-A3 (SK)
Title: Manufacturing process of dilthiazem
Inventor: HYTOENEN MARTTI
IPC: C07C281/10
Filed: 1996-02-15
Abstract: The invention relates to a new process for preparing diltiazem according to Formula (II) <CHEM>  by reacting a compound of Formula (III) <CHEM>  with an n-alkylating agent of Formula (IV) <CHEM> in a mixture of toluene and N-methyl-pyrrolidin-2-one in the presence of finely-divided sodium carbonate, obtaining the desired N-alkylated intermediate product (I), from which diltiazem (II) is prepared directly by allowing (I) to react with an acylating agent.
Patent SK-35994-A3 (SK)
Title: Aqueous varnishes and process for manufacturing car coating varnishes
Inventor: SCHWARTE STEPHAN
IPC: B05D7/16
Filed: 1992-09-12
Abstract: Aq. paint comprises a water-thinnable polyacrylate resin (I) and a capped polyisocyanate (mixt.) (II). Prepn. of (I) comprises mixing components (A) and (B), directly or in stages, in an organic solvent (mixt.), in the presence of at least one polymerisation initiator. The resulting polyacrylate resin is then partly neutralised and dispersed in water. (A) comprises the following components (in wt.%): (a) 40-90 essentially carboxyl gp.-free (meth)acrylic acid ester (mixture), copolymerisable with (b), (c), (d) and (e); (b) 12-50 essentially carboxyl gp.-free ethylenic unsatd. monomer (mixt.) with at least one hydroxyl gp. per molecule, copolymerisable with (a), (c), (d) and (e); and (c) 0-25 essentially carboxyl gp.-free ethylenic unsatd. monomer (mixt.), copolymerisable with (a), (b), (d) and (e). (d) 2.5-15 ethylenic unsatd. monomer (mixt.) which has at least one carboxyl gp. per molecule, copolymerisable (a), (b), (c) and (e); and (e) 0-60 carboxyl gp.-free ethylenic unsatd. monomer (mixt.), copolymerisable with (a), (b), (c) and (d), whereby (a), (b) and (c) are all different. The total pts. per wt.of (a)-(e) is always 100 wt.% and the type and amt. of (a)-(e) is always such that (I) has a hydroxyl value of 60-180, and acid value of 20-100 and a glass transition temp.(Tg) of (-)40 - (+) 60 deg. C..
Patent SK-36794-A3 (SK)
Title: Device for blowing preheated air into shaft furnace
Inventor: BENCK JEAN
IPC: F27D7/04
Filed: 1994-03-28
Abstract: Device for injecting preheated air into a shaft furnace consisting of a number of separate tubular components (10, 12) including an external armouring (18) made of steel and an internal lining made of cast refractory concrete (2), connected in pairs by a spherical joint and a compensator (16). The spherical joint (14) includes a convex ball (24) integrally attached to a first tubular component and capable of pivoting in a concave socket (26) integrally attached to a second tubular component. At least the convex ball (24) of the spherical joint includes a profiled refractory brick (28) anchored in the interior refractory lining (20) made of cast refractory concrete.
Patent SK-52004-A3 (SK)
Title: Non-steroidal anti-inflammatory formulation comprising a granular composition and an extra-granular composition
Inventor: RHOADES TRACEY JANE
IPC: A61P29/00
Filed: 2002-05-30
Abstract: A formulation comprising a granular composition and an extra-granular composition. The granular composition comprises a plurality of solidified melt granules comprising a continuous phase of a non-steroidal anti-inflammatory drug (NSAID). The extra-granular composition comprises a wicking agent which is insoluble in water and comprises at least one of an inorganic material, stearic acid or an insoluble salt thereof, a starch material, a cellulose material or a mixture thereof. The formulation does not contain silicon dioxide.
Patent SK-53896-A3 (SK)
Title: Process for the production of a detergent composition and detergent composition
Inventor: CICCIARI CRAIG
IPC: B01J2/16
Filed: 1994-10-27
Abstract: A process for the production of a detergent composition having a predetermined relative humidity comprising forming a crude detergent composition having a relative humidity in excess of the predetermined level, for example in excess of 30 % and contacting the said crude composition with a preconditioned gas having a relative humidity below the predetermined relative humidity wherein the temperature of the crude composition is maintained below the temperature at which the crude composition agglomerates thereby to form a low relative humidity detergent composition.
Patent SK-66595-A3 (SK)
Title: Pressing tool
Inventor: DISCHLER HELMUT
IPC: B21D39/04
Filed: 1993-11-25
Abstract: PCT No. PCT/EP93/03302 Sec. 371 Date Jun. 2, 1995 Sec. 102(e) Date Jun. 2, 1995 PCT Filed Nov. 25, 1993 PCT Pub. No. WO94/12297 PCT Pub. Date Jun. 9, 1994Disclosed is a press tool for pressing tubular inner and outer nested workpieces (e.g. a pipe end upon which is slid a press fitting). The press tool includes a plurality of clamping components which contain clamping jaws having a continuous circumferential pressing groove (63) shaped in their inner sides, the jaws having a pressing land (65) that extends along only one side of the pressing groove. The press tool also includes a template (44) which fits over the inner nested workpiece but not over the outer slid-on workpiece, the template (44) being positioned on the side of the groove (63) opposite the pressing land (65).
Patent SK-82016-A3 (SK)
Inventor: VIRGALA IVAN
IPC: H02K41/00
Filed: 2016-02-01
Abstract: Vynález je určený na pohyb v potrubí pomocou diferencie trenia medzi štetinami (5) a vnútornou stenou potrubia (13). Zariadenie pozostáva z elektromagnetického lineárneho aktuátora (1), na ktorého kostre je prichytený zadný blok štetín (3) a na jeho výsuvnej tyči (9) je umiestnený predný blok štetín (2). Bloky štetín (2), (3) obsahujú tri unášače (4) a upínače (6) štetín (5). Štetiny (5) sú kontaktnými prvkami medzi zariadením a vnútornou stenou potrubia (13). Dĺžku voľného konca štetín (5), montážny uhol štetín (5) a vzdialenosť štetín (5) od osi zariadenia je možné nastaviť pomocou unášačov (4), upínačov (6) a dištančnými podložkami (8) so skrutkami (7). Štetiny (5) sú montované na zariadenie tak, aby rozpätie ich voľných koncov bolo väčšie než vnútorný priemer potrubia (13), čím vznikne žiadaná normálová a trecia sila medzi stenou potrubia (13) a koncami štetín (5). Štetiny sú montované pod montážnym uhlom vzhľadom k osi stroja, a tak vznikne diferencia trenia medzi stenou potrubia a štetinami pri ich pohybe dopredu a dozadu, čím vzniká výsledný pohyb zariadenia dopredu.
Patent SK-90498-A3 (SK)
Title: Method and device for producing composite board and composite board
Inventor: LOUBINOUX DOMINIQUE
IPC: B32B17/04
Filed: 1998-06-30
Abstract: Method introducing continuously at least one yarn layer (1, 9), which comprising at least two materials having different melting points, in a zone where it is heated at a temperature ranging between said melting points and less than the degradation temperature of the material having the lower melting point, passing over the layer at least a turning bar (4, 12) heated at a temperature ranging between said melting points and less than the degradation temperature of the material with the lower melting point, compressing the layer as it comes out of the bar or bars and cooling it so as to form a composite strip and strip (B) collecting in the form of one or several composite sheets. Apparatus comprising one or plurality of feeding devices (A1, A2) at least one yarn layer (1, 9), at least one device (3, 11) for heating one yarn layer, at least one heated rotating bar (4, 12) on the travel path yarn layer and at least one device (5) for compressing and possibly for cooling yarn layer. Composite sheet contains at least one set bracing unending filaments, embedded approximately parallel, whereby filaments are nested in organic mass and amplitude waving each unending filament with respect to its direction being less than 0.5 mm.
Patent CH-680631G-A3 (CH)
IPC: G04B19/26
Filed: 1991-04-15
Abstract: It includes a tide indicator formed by a tide disc 16 visible through a hatch in the dial 5 and making one revolution in twenty-four hours and driven in rotation by the hand gear. A lunation hand 15 is also driven by the hand gear, at a rate of one revolution in 29.5 days and cooperates with both the tides disc 16 and with signs 20 to 23 representing the phases of the moon, arranged on the dial 5 around the tide disc 16. <IMAGE>
Patent CH-632381G-A3 (CH)
Title: Miniature electronic device
IPC: G04C10/00
Filed: 1980-05-22
Abstract: The device has a battery whose housing consists of two countersunk metal shells (1, 2) which are connected to one another hermetically. The battery housing forms one pole of the battery whilst a second pole is formed by a connection pin (7) which is hermetically connected in one opening of the one housing shell (2) by means of an isolating material (8). One housing shell (2) has a countersunk part (3) in the region of which it is directly connected to the other housing shell (1) and in which other components (9) of the device are arranged. The design of the battery and its connection to the other components of the device permits a design of extremely low volume accompanied by a high degree of rigidity and absolute tightness of the battery over a long period. <IMAGE>
Patent CZ-212591-A3 (CZ)
Title: calorimetric transducer for measuring consumption of heat of heating elements
Inventor: SIMOR STANISLAV
IPC: G01K17/04
Filed: 1991-07-10
Abstract: A calorimetric sensing device is suitable for measurement of thermal energy consumption and consist from the metal calorimetric body (1) with defined cross-section, equipped with heat-conducting ring (11) on inlet, with the first and the second inner temperature sensing elements (2, 3), which are placed on the calorimetric body (1) in defined distance and with the cooler (12) with defined cooling surface on the outlet. The calorimetric body (1) up to the cooler (12) is embraced by thermo-insulating layer (5), with cover (6) on which is placed external sensing element (4). The first and the second inner temperature sensing element (2, 3) and the external sensing element (4) are connected by measuring traces (7) with the evaluating unit (8). The calorimetric sensing device enables to take in consideration at the final calculation of the thermal energy consumption the instantaneous changes of convection conditions as well as changes of the heat transfer coefficient, changes of moisture and the changes in mass of heated air. Thehigh accuracy of measurement is achieved.
Patent CS-225591-A3 (CS)
Title: Wagon
Inventor: AHLBORN GUNTER ING
IPC: B61F/
Filed: 1991-07-19
Abstract: A railway goods wagon essentially has a loading platform (1) and two single-axle (15) or two double-axle running carriages (6-9) with fixedly clamped sets of wheels (8). The loading platform (1) is mounted on the single-axle (15) or double-axle running carriages (6-9) by means of carrying leaf springs (4). The single-axle (15) or double-axle running carriages (6-9) are guided under the loading platform (1) only by vertical guiding elements (10) or axle holder bars (18) arranged on the loading platform (1) and by the axle boxes (16) of the single axles (15) or the frame (7) of the double-axle running carriage. The single-axle (15) or double-axle running carriage (6-9) can thus be vertically moved, can pivot horizontally over a limited angle and can be transversally moved in relation to the loading platform (1). The aim of the invention consists in designing a railway goods wagon that can be driven under goods to be loaded, in particular interchangeable containers, the loading platform (1) of which can be lifted and lowered again into the running position once the goods to be loaded have been deposited onto the loading platform (1), and that can be loaded and unloaded without the need for loading machines extraneous to the wagon. For that purpose, lifting elements are arranged between the axle box cases (16) of the single-axle (15) or the frame (7) of the double-axle running carriage (6-9) on the one hand and the carrying leaf springs (4) on the other hand. The loading platform (1) with the carrying leaf springs (4) can be lifted in relation to the single-axle (15) or double-axle running carriage (6-9) by means of these lifting elements (13).
Patent CZ-237392-A3 (CZ)
Title: Driving mechanism of bells in towers
Inventor: SOLOVSKY JAN
IPC: G10K1/34
Filed: 1992-07-29
Abstract: A mechanism described in this patent consists of the hinge (1) closed to the bell (2) with the driving electric motor (6) connected to the contactless switch (7), while the mentioned hinge is equipped with the shutter (9) used to assure a contact with a motion scanner (10) and of the control unit (8). The control unit (8) is created based on the triggering flip-flop circuit (802) which is connected, through the serial engaged first summation diode (805), catching diode (807) and the switching on transistor (801), to the contactless switch (7) of the driving electric motor (6) and of the operational flip-flop circuit (803). This circuit is connected to the scanner (10) used for scanning of the motion of the bell (2) and it is connected through the first serial engaged summation gate (808, 809) to the blocking flip-flop circuit (812). The blocking gates (814, 815) are serial connected to it, together with the summation diode (807). However, the blocking circuit (812) is connected to the entry of the first summation diode (805), through the balancing gate (813), and the flip-flop circuits (802, 803) have the timing components (804).
Patent CZ-624884-A3 (CZ)
Title: Cathode-ray tube comprising a rectangular panel of the front plate
Inventor: D AMATO RALPH JAMES
IPC: H01J29/86
Filed: 1984-08-17
Abstract: Improvement is provided in the appearance of a color picture type cathode-ray tube including rectangular faceplate with an exterior surface having curvature along both the minor (Y-Y) and major (X-X) axes. At least in the center portion of the faceplate, the curvature along the minor axis is at least 10 percent greater than the curvature along the major axis. Points on the exterior surface near the ends of the major axis, at the edges of the screen, lie in a first plane (P1) perpendicular to the central axis (Z-Z) of the tube; points on the exterior surface near the ends of the minor axis, at the edges of the screen, lie in a second plane (P2) which is spaced from and parallel to the first plane; and points on the exterior surface near the ends of the diagonals of the rectangular faceplate, at the edges of the screen, lie in a third plane (P3) which is spaced from and parallel to the first plane. The three planes are spaced from the center portion of the faceplate in the order of second plane, first plane and third plane. Further relative dimensions are detailed. <IMAGE>