baber/WOPTO huggingface dataset:
Patent MX-2022013344-A (MX)
Title: Systemic formulation of a pyridinone derivate for tg2-related diseases.
Inventor: MOHR WOLFGANG
IPC: A61K9/16
Filed: 2021-04-24
Abstract: The present invention relates to a formulation in particular an oral formulation for the prophylaxis and treatment of TG2-related disorders like fibrosis in particular diabetic nephropathy and/or diabetic associated non-alcoholic steatohepatitis (NASH) and/or non-alcoholic steatohepatitis, and its use in the prophylaxis and/or treatment of fibrosis in particular nephropathy, NASH, idiopathic pulmonary fibrosis, and cystic fibrosis. Further, the present application relates also to the use of (S,E)-methyl-7-(1-(2-(2- ethylbutylamino)-2-oxoethyl)-2-oxo-1,2-dihydro-pyridin-3-ylamin o)-6-(1-methyl-1H- imidazole-5-carboxamido)-7-oxohept-2-enoate as hepatoprotectant, i.e. as hepatoprotective agent. In addition the present invention relates to a pharmaceutical composition comprising (S,E)-methyl-7-(1-(2-(2-ethylbutylamino)-2-oxoethyl)-2-oxo-1,2- dihydro-pyridin-3-ylamino)-6-(1-methyl-1H-imidazole-5-carboxami do)-7-oxohept-2- enoate for use as hepatoprotective agent and for use in the protection of the liver against liver toxicity, the improvement of liver function, and/or in the prophylaxis or treatment of a liver disease or liver disorder.
Patent MX-2022013692-A (MX)
Title: 3-azabicyclo(3.1.0)hexane derivatives having kdm5 inhibitory activity and use thereof.
Inventor: TAKAHASHI HIDENORI
IPC: A61P35/00
Filed: 2021-05-06
Abstract: The present invention provides KDM5 inhibitor. The compound disclosed herein represented by the general formula (I) : wherein all symbols have the same meanings as the definitions described in the specification; or a salt thereof is useful as a prophylactic and/or therapeutic agent for cancer, Huntington's disease, Alzheimer's disease and the like.
Patent MX-2022016079-A (MX)
Title: Glass compositions, fiberizable glass compositions, and glass fibers made therefrom.
Inventor: LI HONG
IPC: C03C13/00
Filed: 2021-06-24
Abstract: Glass compositions suitable for fiber forming having rare earth oxides (RE<sub>2</sub>O<sub>3</sub>) and glass fibers having a high modulus are disclosed. The glass composition may include SiO<sub>2</sub> from about 44.5 to about 64 weight percent, Al<sub>2</sub>O<sub>3</sub> from about 12 to about 32 weight percent, CaO from about 0.1 to about 15.5 weight percent, MgO from about 5 to about 22 weight percent, Fe<sub>2</sub>O<sub>3</sub> less than 1 weight percent, TiO<sub>2</sub> less than 2 weight percent, Na<sub>2</sub>O less than 3 weight percent, Y<sub>2</sub>O<sub>3</sub> up to 12 weight percent, CeO<sub>2</sub> up to 6 weight percent, ZnO up to 4 weight percent, and B<sub>2</sub>O<sub>3 </sub>less than 4.5 weight percent. The glass compositions can be used to form glass fibers and incorporated into various composites.
Patent MX-PA01000974-A (MX)
Title: Compressed digital-data seamless video switching system.
Inventor: DEO FRANK P
IPC: H04N5/00
Filed: 1998-12-16
Abstract: An interactive cable television system is disclosed which utilizes a standard cable television distribution network for simultaneously providing a plurality of viewers with an interactive television program comprising a plurality of signals related in time and content. Video signals are transmitted in a digital format, more than one signal being multiplexed onto a data stream on a single channel. The video signals may be compressed for efficiency. A receiver, in conjunction with a signal selector, selects a particular NTSC channel for playback, then selects a particular video signal from the data stream, and decompresses the video signal for playback. Seamless switching between video signals on different channels is provided. An alternative embodiment is disclosed wherein the various signals which comprise the interactive program are switched at the head end rather than at the receiver. The multiple choice control unit selects a desired signal by relaying the multiple choice selections of the user through a relay box back to a remotely located switching station. The switching station routes the correct video signal down the appropriate cable channel for the particular user.
Patent MX-PA01008606-A (MX)
Title: Novel sulfonamide compounds and uses thereof.
Inventor: MUNOZ BENITO
IPC: A61P25/00
Filed: 2000-02-22
Abstract: In accordance with the present invention, there is provided a novel class of sulfonamide compounds. Compounds of the invention contain a core sulfonamide group. Variable moieties connected to the sulfur atom and nitrogen atom of the sulfonamide group include substituted or unsubstituted hydrocarbyl moieties, substituted or unsubstituted heterocycle moieties, polycyclic moieties, halogen, alkoxy, ether, ester, amide, sulfonyl, sulfonamidyl, sulfide, carbamate, and the like. Invention compounds are capable of a wide variety of uses. For example sulfonamide compounds can act to modulate production of amyloid beta protein and are useful in the prevention or treatment of a variety of diseases. Pharmaceutical compositions containing invention compounds are also provided. Such compositions have wide utility for the prevention or treatment of a variety of diseases.
Patent MX-PA01008997-A (MX)
Title: Method for recovering communication service.
Inventor: SEEKINS DAVID S
IPC: H04W36/00
Filed: 2000-03-02
Abstract: A communication device (102) has a serving and neighbor list (202) and a bandmap (204, 206). Upon losing communication service (402) the device begins alternately scanning the serving and neighbor list (SNL) and subsections (302, 304, 306, 308) of the bandmap. If an appropriate carrier is found while scanning the SNL, the device reconnects to the serving system. While scanning the subsections of the bandmap, the device creates and maintains a list (312) of suitable carriers. If no carriers are found corresponding to the SNL, a serving cell is selected from the list (312).
Patent MX-PA01009185-A (MX)
Title: Pivotable guidebeam switch.
Inventor: LIN CHEN-TSE
IPC: E01B25/12
Filed: 2000-03-10
Abstract: A pivotable switch arrangement (10), as shown in Figure 1, for switching a guided vehicle guidebeam including a vehicle guideway (12), a main guidebeam (14) secured to the vehicle guideway, and a plurality of turnout guidebeams (16) secured to the vehicle guideway and spaced from the main guidebeam. Each of the turnout guidebams includes an extendable locking pin (17) at an end facing the main guidebeam. A pivotable guidebeam section (24) is pivotally connected to the guideway adjacent an end of the main guidebeam. The guidebeam section defines a cavity (34). A drive mechanism (39) is connected to the guidebeam section and is configured to pivot the guidebeam section between the turnout guidebeams, and align an end of the guidebeam section with one of the turnout guidebeams. The locking pin engages the cavity when the guidebeam section is aligned with the one of the turnout guidebeams.
Patent MX-PA01009825-A (MX)
Title: Sprayable powder of non-fibrillatable fluoropolymer.
Inventor: HUESMANN PETER L
IPC: C09D5/03
Filed: 2000-03-30
Abstract: The invention provides for sprayable powder comprising friable granules of agglomerated primary particles of non-fibrillatable fluoropolymer and, optionally, at least one other component, the powder having a bulk density of at least 20g/100cc and average particle size of 5 to 100 micrometers. The sprayable powder is preferably free of water immiscible liquid, and more preferably free of halocarbon liquid. Included among the other components are inorganic fillers, pigments, high temperature resistant polymer binders. In an other embodiment, the invention provides for a sprayable powder comprising friable granules of agglomerated primary particles of a first non-fibrillatable fluoropolymer and at least one other non-fibrillatable component. The invention further provides for a process for preparing the sprayable powder by spray drying a liquid dispersion. In a preferred embodiment, the process includes densifying the granules of agglomerated primary particles that result from spray drying. Densifying may be carried out by mechanical compaction or by contacting the granules with a heated gas to form a fluidized bed. Optional steps of communication and heat treatment may be employed to achieve a desired bulk density and particle size for specific applications.
Patent MX-PA01009882-A (MX)
Title: Heeling apparatus and method.
Inventor: ADAMS ROGER R
IPC: A63C17/08
Filed: 2000-03-31
Abstract: A heeling apparatus includes a shoe with a unique feature in the heel that allows one to walk, run, or roll seamlessly. The appearance is that of normal footwear because of the covert wheel assembly. The stealth wheel (16) in the heel gives one the ability to roll or slide in areas you could only walk. Heeling is a new activity that employs a unique method of rolling and requires a newly learned skill set of balance, positioning, and coordination.
Patent MX-PA01010194-A (MX)
Title: Circulating fluidized bed reactor with selective catalytic reduction.
Inventor: DONALD L WIETZKE
IPC: B01J8/38
Filed: 2001-02-06
Abstract: A CFB reactor or combustor having a selective catalytic reduction (SCR) system (150) employed downstream of the CFB reactor or combustor furnace (10) together with a dry scrubber system (220) to achieve enhanced NOx reduction.
Patent MX-PA01012039-A (MX)
Title: Single motor drive system for stretch wrapping machine.
Inventor: GALE W HUSON
IPC: B65B11/02
Filed: 2001-11-23
Abstract: In a stretch film wrapping system, a single motor drive system (32) is provided for controlling both the rotation of a rotational boom member (30) with respect to a static boom member (28) and the elevation of a stretch film roll carriage assembly (38) movably mounted upon a wrapping mast (36) fixedly connected to the rotational boom member. A cable drum assembly (55) is mounted upon a driven shaft (50) and biased by a spring mechanism (72) to a first position such that when the boom member is rotated, a cable (68) is wound upon the cable drum assembly (55) elevating the stretch film roll carriage assembly (38). A solenoid mechanism (76) biases the cable drum assembly (55) to a second position such that the stretch film carriage assembly (38) is maintained at a predetermined elevational level whereby stretch film is wrapped in a reinforcing mode. A second solenoid mechanism (78) biases the cable drum assembly (55) to a third position such that the stretch film carriage assembly (38) i s moved to its lowermost position for a new wrapping operation cycle.
Patent MX-PA02000465-A (MX)
Title: CYCLIC PEPTIDE DERIVATIVES AS INHIBITORS OF INTEGRIN alphaV.
Inventor: GOODMAN SIMON
IPC: A61P17/02
Filed: 2000-07-03
Abstract: The invention relates to novel peptide derivatives of formula (I): Cyclo-(Arg-X1-Asp-X2-X3-X4-X5-X6-R1); which are biologically active as ligands of integrin alphavbeta6, X1 representing Ser, Gly or Thr; X2 representing Leu, Ile, Nle, Val or Phe; X3 representing Asp, Glu, Lys or Phe; X4 representing Gly, Ala or Ser; X5 representing Leu, Ile, Nle, Val or Phe; X6 representing Arg, Har or Lys; and R1 being left out or representing one or more omega-aminocarboxylic acid radicals, said omega-aminocarboxylic acid radical(s) being 500 to 2500 pm in length. Said amino acids can also be derivatised and the D and L forms of the optically active amino acid radicals are enclosed. The invention also relates to the physiologically suitable salts and solvates of the inventive derivatives.
Patent MX-PA02001816-A (MX)
Title: Variable firing rate fuel burner.
Inventor: RAYMOND I HALLIT
IPC: F23D14/36
Filed: 2002-02-20
Abstract: A variable firing rate fuel burner has a tubular body configuration defined by a central pilot tube coaxially circumscribed by intermediate and outer firing tubes. A pilot fuel-air mixture is flowed through the pilot tube and ignited to maintain a pilot flame at the open outlet end of the burner body. During firing of the burner, separate fuel-air mixtures are flowed through an intermediate annulus between the intermediate firing tube and the pilot tube, and an outer annulus between the intermediate firing tube and the outer firing tube. As these fuel-air mixtures exit the burner body they are ignited by the pilot flame, with the fuel-air mixture exiting the outer annulus serving as a flame shaping mechanism to provide the overall burner flame with a controlled, elongated shape. By using two separate fuel-air mixture flows surrounding the pilot fuel-air mixture flow, the firing rate of the burner may be easily modulated, and the burner may be simultaneously operated with two different types of fuel.
Patent MX-PA02001861-A (MX)
Title: NOVEL INTEGRIN agr;V.
Inventor: OLIVER SCHADT
IPC: A61P7/02
Filed: 2000-08-04
Abstract: The invention relates to novel compounds of formula (I) which are biologically active when present as ligands of the integrin agr;vbgr;3: X Y Z R1 CH2 R2(R4) CH2 CO R5 wherein the meaning of X, Y, Z, R1, R2, R4 and R5 is given in Claim 1. The invention also relates to the physiologically acceptable salts and solvates of said compounds.
Patent MX-PA02002408-A (MX)
Title: Modular display integrated by panels.
Inventor: MARIA JOSEFA LARROSA MARTINEZ
IPC: A47F3/00
Filed: 2002-03-05
Abstract: Described is a modular display integrated by panels, which is assembled upon interconnecting said panels therebetween so as to form one or several adjacent walls, said walls including a base element and presenting a cap disposed on the last panel of each wall in order to protect the inner portion of the panel, as well as allowing decorative or advertising elements to be easily and simply placed on the display. A plurality of displaying racks are attached every two side walls by means of a pair of box arrangements, which support different type of products to be displayed. The invention comprises an easy, resistant and lightweight structure ranging in the storing capacity and dimensions thereof according to the number of interconnected panels, the number of walls and the arrangement of the racks for displaying the products.
Patent MX-PA02005160-A (MX)
Title: Method for production of polyether alcohols.
Inventor: GEORG HEINRICH GROSCH
IPC: C08G18/48
Filed: 2000-12-06
Abstract: The invention relates to a method for the production of polyether alcohols by catalytic addition of at least two alkylene oxides to H functional starting materials. Said method is characterised in that at least one multi metal cyanide compound is used as catalyst and in the course of the addition to the starting material at least one oxyalykylene unit is incorporated, during which a common dosing of at least two alkylene oxides occurs, whereby during said common dosing the ratio of the amounts of alkylene oxides to each other is varied.
Patent MX-PA02006093-A (MX)
Title: Embryonic or stemlike cells produced by cross species nuclear transplantation.
Inventor: LANZA ROBERT
IPC: C12N5/10
Filed: 2000-05-10
Abstract: Method of nuclear transfer involving the transplantation of differentiated donor cell nuclei into enucleated oocytes of a species different from the donor cell, in conjunction with compatible cytoplasm andor mitochondria (of same species as donor), are provided. The resultant nuclear transfer units are useful for the production of isogenic embryonic stem cells, in particular human isogenic embryonic or stem cells. These embryonic or stemlike cells are useful for producing desired differentiated cells and for introduction, removal or modification, of desired genes, e.g., at specific sites of the genome of such cells by homologous recombination. These cells, which may contain a heterologous gene, are especially useful in cell transplantation therapies and for in vitro study of cell differentiation. Nuclear transfer efficiency is enhanced by introduction of compatible cytoplasm or mitochondrial DNA (same species or similar to donor cell or nucleus). Also, nuclear transfer efficiency can further optionally be enhanced by genetically altering donor cells to inhibit apoptosis, by selecting for a specific cell cycle andor by culturing under conditions that enhance embryonic growth and development.
Patent MX-PA02009692-A (MX)
Title: Device for rotational stabilization of bone segments.
Inventor: HALL HARRY THOMAS IV
IPC: A61B17/58
Filed: 2001-03-15
Abstract: A device for rotational stabilization of bone segments comprising a bone plate, a bone lag screw (18), and a locking collar (24). The bone lag screw (18) has a bone engagement end, a distal end, and a keyed cross sectional profile, the bone engagement end configured for engaging a first bone segment. The bone plate has a flat portion for engaging a second bone segment and a barrel portion having an internal bore for slidably receiving the lag screw (18). The locking collar (24) has a keyed internal profile that mates with the keyed cross sectional profile of the lag screw (18) to rotationally couple the locking collar (24) and the lag screw (18) when the lag screw (18) is inserted through the locking collar (24), and an outer surface configured and dimensioned for (1) free rotation, in a first position, within the internal bore of the bone plate barrel portion and (2) frictionally engaging, in a second position, the internal bore of the bone plate barrel portion to resist or prevent rotation of the collar relative to the bone plate, and thereby resist or prevent rotation of the lag screw (18) relative to the bone plate.
Patent MX-PA02009704-A (MX)
Title: Pre crimped tie components.
Inventor: DESPAULT MARC P
IPC: B65D63/02
Filed: 2001-03-28
Abstract: A tie component (20) comprising first and second pre crimped portions. Each pre crimped portion has a plurality of alternating indentations (22) and projections (24). The pre crimped portions are joined by alignment and relative movement with respect to one another such that at least one of the first portion projections engages at least one of the second portion indentations and at least one of the second portion projections engages at least one of the first portion indentations.
Patent MX-PA02010865-A (MX)
Title: Treatment of congestive heart failure.
Inventor: PRESSLER MILTON LETHAN
IPC: A61P9/04
Filed: 2001-03-22
Abstract: Combinations of diuretics and vasopressin antagonists are useful to slow and reverse the symptoms and process of congestive heart failure, to increase the excretion of water in the urine, and to decrease the excretion of sodium and potassium ions in urine. Preferred vasopressin antagonists have the formula (I) wherein R and R5 are hydrogen or lower alkyl; R1, R2, and R3 are hydrogen, halo, alkyl, alkoxy, and amino; and R4 is hydrogen or phenyl, and a pharmaceutically acceptable salt thereof.
Patent MX-PA02011344-A (MX)
Title: Hydroxylamine esters as polymerization initiators.
Inventor: PETER NESVADBA
IPC: C07D487/10
Filed: 2001-05-14
Abstract: The invention relates to novel cyclic and open chain hydroxylamine esters and polymerizable compositions comprising these hydroxylamine esters and an ethylenically unsaturated monomer or oligomer. The invention also relates to use as polymerization initiators and to the use of known hydroxylamine esters selected from the group consisting of HALS compounds and the novel hydroxylamine esters for the controlled degradation of polypropylene and for achieving a controlled increase in the molecular weight of polyethylene.
Patent MX-PA02012175-A (MX)
Title: Cap for a lancing device.
Inventor: MOERMAN PIET
IPC: A61B5/15
Filed: 2001-06-08
Abstract: A cap for a lancing device for lancing dermal tissue is provided. The cap includes a cap body having a proximal end for connecting to the distal end of the housing of the lancing device and a contact ring attached to the distal end of the cap body. The contact ring includes an opening for a portion of the lancet of the lancing device to pass therethrough. The contact ring has a multi-contoured surface oriented generally about an axis distinct from the axis of motion of the lancet. The multi-contoured surface is designed to pressure the dermal tissue to facilitate expression of a fluid sample after lancing the dermal tissue. The fluid sample can include blood, interstitial fluid, or both.
Patent MX-PA03003304-A (MX)
Title: Coiled hose.
Inventor: MEJIA EDSON A
IPC: F16L11/12
Filed: 2003-04-14
Abstract: A water hose includes a heclically shaped coiled tube having interior and exterior elliptical cross-sections with a flexural modulus greater than the flexural modulus of a coiled tube having interior and exterior circular cross-sections and the same neutral center line length as the elliptical cross-sections, but otherwise having the same properties as the elliptical cross-sections. The tube is made of extruded plastic resin having a durometer hardness measurement approximately in the range of 70-80 Shore A and has on its periphery ridges extending longitudinally at right angles to the elliptical cross-sections. In first and second embodiments, the elliptical cross-sections have major and minor axes respectively extending in the direction of the coil longitudinal axis and in planes extending at right angles to the longitudinal axis, and vice versa.
Patent MX-PA03004301-A (MX)
Title: Process for molding laminated candy and resultant products thereof.
Inventor: ZERBY CHRISTINE
IPC: A23G3/34
Filed: 2001-11-07
Abstract: The invention relates to methods of molding edible laminated structures that have at least one first fluid material of a sticky or flowable mass interleaved between thin layers of a second fluid material, wherein neither of the first fluid material nor the second fluid material is a hard candy mass.
Patent MX-PA03005221-A (MX)
Title: Pharmaceutical dronedarone composition for parenteral administration.
Inventor: THIERRY BREUL
IPC: A61K47/24
Filed: 2001-12-10
Abstract: The invention concerns a pharmaceutical composition for parenteral administration, characterised in that it comprises: dronedarone or one of its pharmaceutically acceptable salts as active principle; a physiologically acceptable buffer solution capable of maintaining the pH of the composition between 3 and 5; a physiologically acceptable water-soluble bgr;-cyclodextrin derivative.
Patent MX-PA03009938-A (MX)
Title: Fused pyrimidines as antagonists of the corticotropin releasing factor (crf).
Inventor: BENEDETTA PERINI
IPC: A61P17/02
Filed: 2002-04-30
Abstract: The present invention provides compounds of formula (I) including stereoisomers, prodrugs and pharmaceutically acceptable salts or solvates thereof wherein the variables are as defined in the description, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of conditions mediated by corticotropin-releasing factor (CRF).
Patent MX-PA03010651-A (MX)
Title: Process control system with a charging function.
Inventor: OLIVER KAISER
IPC: G06Q50/00
Filed: 2002-07-26
Abstract: The invention relates to a process control system (5) comprising a calculating unit (10) enabling a charge value (W) to be determined from operations (7) occurring in the process control system (5). Preferably, said process control system (5) comprises a process control computer (15) with a web server (30) and a client computer (25) which is used to access the process control computer (15) via Internet (20). The charging value (W) is especially a service fee which is to be paid to an application service provider by a user of the process control system (5).