baber/WOPTO huggingface dataset:
Patent EA-015672-B1 (EA)
Title: Tissue protective peptides and uses thereof
Inventor: CERAMI ANTHONY
IPC: A61K38/00
Filed: 2006-08-07
Abstract: The present invention is directed to novel tissue protective peptides. The tissue protective peptides of the invention may bind to a tissue protective receptor complex. In particular, the present invention is drawn to tissue protective peptides derived from or sharing consensus sequences with portions of cytokine receptor ligands, including Erythropoietin (EPO), that are not involved in the binding of the ligand to the receptor complex, e.g., to the EPO receptor homodimer. Accordingly, the tissue protective peptides of the invention are derived from the amino acid sequences of regions of cytokine receptor ligands that are generally located on or within the region of the ligand protein that is opposite of the receptor complex, i.e., are generally derived from amino acid sequences of regions of the ligand protein that face away from the receptor complex while the ligand is bound to the receptor. The invention is further directed to the consensus sequences for use in engineering a synthetic tissue protective peptide. These tissue protective peptides also include fragments, chimeras, as well as peptides designed to mimic the spatial localization of key amino acid residues within the tissue protective receptor ligands, e.g., EPO. The invention further encompasses methods for treating or preventing a disease or disorder using tissue protective peptides of the current invention. The invention also encompasses methods for enhancing excitable tissue function using tissue protective peptides of the current invention.
Patent EA-014885-B1 (EA)
Title: Window
Inventor: KAISER KONRAD
IPC: E05B1/00
Filed: 2007-03-16
Abstract: A window, in particular a turn-and-tilt window, comprises a window handle (2) which has a handle (4) for manual movement, in particular rotation, of a window casement (3) of the window (1), wherein switching elements (19, 23, 24) are provided on the window (1) and/or window handle (2). According to the invention, the switching elements (19, 23, 24) are coupled to a controlling means for actuating at least one peripheral device (5-17) arranged at a distance from the window (1). As a result, a central switching system for various peripheral devices (5-17) can be formed on the window (1).
Patent EA-015784-B1 (EA)
Title: Stretchable nonwoven fabric, absorbent article and method of producing absorbent article
Inventor: MUKAI HIROTOMO
IPC: D04H1/42
Filed: 2007-12-06
Abstract: It is intended to provide a disposable diaper, which is comfortable to wear without damaging the absorbing performance of an absorbent at wearing, and a method of producing the disposable diaper. In stretchable nonwoven fabric sheets (9a, 9b) which are provided in the side of a chassis (2) not being in contact with the skin and made of a stretchable thermoplastic fiber and a heat adhesive fiber having a melting point lower than the thermoplastic fiber, a low-stretchable part (25), wherein the stretchability of the stretchable nonwoven fabric sheets (9a, 9b) has been lowered, is formed at least in an area overlapping an absorbent (4) in the thickness direction. This low-stretchable part (25) is formed by heating and pressurizing the corresponding area in the state of stretching the master roll (19) of the stretchable nonwoven fabric.
Patent EA-017200-B1 (EA)
Title: Lubricating pinion, method for manufacture thereof and lubricating device
Inventor: PALUNCIC ZDRAVKO
IPC: F04C2/08
Filed: 2007-06-28
Abstract: The invention relates to a lubricating pinion (1) for the application onto at least one gear wheel comprising an external tooth system onto which at least one lubricant outlet (8) discharges, and at least two lubricating pinion parts (1a, 1b) that can be respectively connected to one another along a radial parting plane (E), perpendicular to the rotation axis of the lubricating pinion. At least one lubricant channel (6), which can be connected to the at least one lubricant outlet (8), extends in the parting plane. To provide lubrication if the lubricant supply is interrupted the surface of the lubricating pinion parts (1a, 1b) features a profiling, e.g., in the region of the external tooth system, small pockets or depressions are formed in which the lubricant can accumulate, the axially extending channels 7 and the transverse grooves or channels (9) connected on one side to the lubricant outlets (8) for lubricant and on the other side open for supplying lubricant to an element to be lubricated.
Patent EA-015583-B1 (EA)
Title: Stator for an electric machine
Inventor: ANTONYUK OLEG VIKTOROVICH
IPC: H02K1/20
Filed: 2008-06-02
Abstract: The invention relates to a stator for a turbogenerator provided with the affective gas cooling of the coil and teeth thereof. A core (2) with a winding (3) is arranged in the stator body (1). The core consists of the packages of steel plates (5) and ventilating channels (7). Said ventilating channels are formed by ventilating spreaders (8) and are closed on the side of the bore of the stator core. A high-pressure chamber (9) located in the space between the body and the core is provided with air ducts (10) which are disposed on the external surface of the core along the total length thereof in each second intertooth interval. Said air ducts are connected to the ventilating channels on one side and to a low-pressure chamber, which is situated in the space of the face parts of the stator winding, on the other side. The ventilating spreaders are placed in the tooth area in such a way that the cooling gas flow is shifted in an axial direction towards the adjacent ventilating channel via through holes (6). Said ventilating spreaders are arranged in a heelpiece area in such a way that the cooling gas flow in the even ventilating channels passes from the high-pressure chamber to the tooth area and in the uneven ventilating channels said flow passes from the tooth area to the air ducts.
Patent EA-017494-B1 (EA)
Title: Method for depositing a thin layer and product thus obtained
Inventor: NADAUD NICOLAS
IPC: C03C17/09
Filed: 2008-01-04
Abstract: The invention relates to a method for processing at least one continuous thin layer deposited on the first surface of a substrate, characterized in that said at least one thin layer is heated at a temperature of at least 300°C while maintaining a temperature lower than or equal to 150°C at the surface of said substrate opposite said first surface in order to increase the crystallization rate of said thin layer while maintaining it continuous and without any fusion step of said thin layer. The invention also relates to a material that can be obtained using said method.
Patent EA-018304-B1 (EA)
Title: Casement for a glass window or leaf for a glass door, and window system
Inventor: KOELZER STEFAN
IPC: E06B3/263
Filed: 2008-08-06
Abstract: The present invention relates to a casement (1) for a glass window or a leaf for a glass door, a window or door frame and a window system containing a casement and a window frame. The casement or leaf comprises an insulating material layer arrangement located between two hollow profiles (3, 4). The insulating material layer arrangement has at least one first insulating layer (5) which is configured for high strength, and at least one second insulating layer (6) which is configured for high thermal insulation. Between the two wood profiles (3, 4), a lateral insulating layer (8) which is configured for high thermal insulation is arranged substantially perpendicularly to the direction of extent of the insulating material layer arrangement.
Patent EA-019615-B1 (EA)
Title: Harvested crop haulage system for forage harvester with discharge accelerator and air blower for providing air flow
Inventor: BAEURICH MATTHIAS
IPC: A01D43/077
Filed: 2010-03-17
Abstract: Harvested crop haulage system for a forage harvester (10) comprises a discharge accelerator (24) with a receiving conveyor (48) for feeding crop and a housing (42) with the conveyor therein, the housing comprises a crop inlet (44) for chopped harvested crop and at least one air blower (56) which impacts the harvested crop with a directional air flow that flows in a direction of conveyance of the harvested crop and performed within the housing (42) of the discharge accelerator (24), the air blower (56) is arranged inside or outside the housing (42) and comprises air paddles (58) mounted on the conveyor (48) shaft (50), between the conveyor (48) and the air blower (56) a partition (60) is provided, wherein the air conveyor paddles (58) of the air blower (56) are enclosed in the circumferential direction by a wall (66), having an opening (70) through which the crop directed by the airflow can be acted upon.
Patent EA-023109-B1 (EA)
Title: Lubrication composition with an adaptable coefficient of friction, for a threaded element of a threaded tubular connection component
Inventor: PINEL ELIETTE
IPC: C10N30/12
Filed: 2009-10-05
Abstract: A film-forming lubrication composition for make-up of threaded connections, intended to cover at least one threading (FE, FI) and a make-up abutment (BVM, BVF) of a threaded element (EM, EF) of a component (T2, T1) of a threaded tubular connection (JF) with a solid state film which adheres to the threading (FE, FI) and to said make-up abutment (BVM, BVF), said make-up abutment (BVM, BVF) being intended to bear against another abutment (BVF, BVM) of another component (T1, T2) of said threaded tubular connection (JF) during the terminal make-up phase, and said lubrication composition comprising a matrix. The matrix further comprises at least one rheoresistant material selected so as to endow said composition, as a complement to lubrication, with a shouldering torque which is at least equal to a threshold value.
Patent EA-018824-B1 (EA)
Title: P70 S6 KINASE INHIBITOR AND mTOR INHIBITOR COMBINATION THERAPY
Inventor: GEEGANAGE SANDARUWAN
IPC: A61K31/436
Filed: 2009-11-04
Abstract: The present invention provides a product comprising the compound 4-[4-[4-(4-fluoro-3-trifluoromethylphenyl)-1-methyl-1H-imidazol-2-yl]piperidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine, or a pharmaceutically acceptable salt thereof, and an mTOR inhibitor which is rapamycin as a combined preparation for simultaneous, separate or sequential use in therapy, in particular for use in the treatment of glioblastoma multiform, adenocarcinomas of the colon, non-small-cell lung cancer, small-cell lung cancer, cisplatin-resistant small-cell lung cancer, ovarian cancer, leukemia, pancreatic cancer, prostate cancer, mammary carcinoma, renal cell carcinoma, multiple myeloma, Kaposis Sarcoma, Hodgkins lymphoma, lymphangioleiomyomatosis, Non-Hodgkins lymphoma or sarcoma; use of said product for the treatment of the above diseases; and a method of treating a cancer selected from the above comprising administering to a patient in need thereof the compound 4-[4-[4-(4-fluoro-3-trifluoromethylphenyl)-1-methyl-lH-imidazol-2-yl]piperidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine, or a pharmaceutically acceptable salt thereof, and an mTOR inhibitor as rapamycin in amounts that in combination are effective.
Patent EA-023072-B1 (EA)
Title: Polyalkyl(meth)acrylate compositions free of sulphur-containing, metallic and halogenated compounds and with a low degree of residual monomers, process for the preparation thereof and uses thereof
Inventor: DOLMAZON NELLY
IPC: C10M145/14
Filed: 2010-03-25
Abstract: The subject matter of the invention is polyalkyl(meth)acrylate compositions comprising a linear or branched C8, or more, fatty chain, said polymers comprise at least one ethylenic unsaturation and have a weight-average molecular mass Mw of less than 20000 g/mol, wherein the polymer composition is free of sulphur-containing, metallic and halogenated compounds and has the degree of residual monomers measured by GPC less than or equal to 10% by mass, preferably less than or equal to 7% by mass. The subject matters of the invention are also the preparation and the use of said polymers.
Patent EA-028926-B1 (EA)
Title: Medical mouthpiece for powder medicament
Inventor: CHEN QINGTANG
IPC: B01D46/00
Filed: 2011-12-15
Abstract: Provided is a powder medicament mouthpiece comprising at least one section of through suction tube (1) and a filter (2). One end of the suction tube is a medicament inlet, and the other end (16a) is a suction outlet. The filter (2) is arranged within the suction tube (1). The powder medicament mouthpiece can be connected to multiple models of dry powder inhalers to separate powder medicament from dry powder, and allows for significantly improved efficacy.
Patent EA-024813-B1 (EA)
Title: Outlet seal for the cathode rods of an aluminium electrolytic cell
Inventor: CARROLL Toni
IPC: C25C3/08
Filed: 2011-12-26
Abstract: The invention relates to structural components of cathode devices in electrolytic cells for the production of aluminium. The seal comprises a device connected to a lined cathode shell having apertures for the passage of cathode rods, which device, located on the face of the electrolytic cell, is intended to house a sealing means and is made from an elastic, gas-proof and heat-proof material in the form of a sleeve that is hermetically connected by one end to the cathode shell. A plate with an opening is disposed on the inner side of the aperture for the passage of cathode rods, around the periphery thereof, and the sealing means, which is disposed in the gap formed by the cathode rod and the wall of the cathode shell, allows the cathode rod to slide relative to the cathode shell while ensuring that the seal remains tight. The technical result is that of providing that the seal remains tight during any movement of the cathode rods when the aluminium electrolytic cell is in operation.
Patent EA-025689-B1 (EA)
Title: Method for highly expressing recombinant protein of engineering bacteria and use thereof
Inventor: QIU XIAOQING
IPC: C12R1/19
Filed: 2012-11-23
Abstract: Provided are a method for highly expressing a recombinant protein of engineering bacteria and the use thereof. The method comprises the following steps: (1) engineering bacteria of Escherichia coli with pET system are transfected with recombinant mutated plasmid to obtain positive monoclonal colonies; (2) the positive monoclonal colonies are enriched to obtain a seed bacteria solution, and the seed bacteria solution is induced to enrichment and growth in a large amount; and (3) the bacteria supernatant containing the recombinant protein as the expression target is separated, and then the recombinant protein in the bacteria supernatant is extracted and purified. The method is characterized in that the engineering bacteria of Escherichia coli with pET system are E. coli B834 (DE3). The components of the mass enrichment medium and the protein purification steps are also optimized such that a significant improvement in the yield and purity of the protein is achieved and the method is suitable for applying to the large-scale production of recombinant protein expressed by the engineering bacteria of Escherichia coli.
Patent EA-033620-B1 (EA)
Title: Medical formulation for prevention and treatment of psoriasis
Inventor: VELIEVA MAKHBUBA NABI KYZY
IPC: A61K36/185
Filed: 2014-04-25
Abstract: The invention relates to the medice, namely to dermatology and may be used to treat psoriasis. The goal of the invention is to increase the effectiveness of psoriasis treatment via optimizing the balm compound, and using oil extracts of various medicinal herbs that improve metabolic and regenerating processes in skin. The suggested medical formulation to prevent and treat psoriasis consists of the components taken in grams: thick licorice extract - 5.0-10.0; licorice meal - 10.0-20.0; milk thistle oil - 5.0-10.0; milk thistle meal - 10.0-20.0; sea buckthorn oil - 5.0-10; tea tree essential oil - 5.0-10.0; salt of the dead sea - 0.5-1.0; birch tar - 3.0-5.0; salicylic acid - 2.0-3.0; tincture of 5% iodine - 5 drops; naphthalane - the rest, the formulation being produced as ointment. The essence of the invention is that the task to create a compound to prevent and treat skin diseases is solved via quantitative and qualitative selection of components that would ensure a comprehensive effect on the tissue affected by the medical agent, entailing specific activity of high quality and a wide range, combined with simultaneous reduction and exclusion of side-effects, while the quantitative and qualitative composition of the suggested compound succeeds completely in creating a highly effective agent to treat skin diseases.
Patent EA-026296-B1 (EA)
Title: Process for the recovery of bitumen from an oil sand
Inventor: ANDREI MARIA
IPC: C10G1/04
Filed: 2012-10-24
Abstract: The present invention relates to a process for the recovery of bitumen from an oil sand comprising the following phases in succession: (a) mixing an oil sand with a diluent capable of reducing the viscosity and density of the bitumen contained in said oil sand, obtaining a first mixture (slurry) comprising diluted bitumen; (b) mixing said slurry with a basic aqueous solution (BAS) possibly containing salts to increase its ionic strength, capable of removing said diluted bitumen from said oil sand containing it, obtaining a second mixture (BAS-slurry) which can be separated into (I) a liquid phase comprising said diluted bitumen, a fraction of oil sand free of the bitumen removed and water; (II) a sediment comprising the remaining fraction of said oil sand free of the bitumen removed, water and residual hydrocarbons which can be eliminated by subsequent washings; (c) separating a liquid phase comprising said diluted bitumen removed, from said BAS- slurry mixture; (d) recovering, from said liquid phase separated in phase (c), the removed diluted bitumen contained therein.
Patent EA-031634-B1 (EA)
Title: Substance for collecting petroleum or petroleum products from surface of water and utilization method thereof
Inventor: ELAGIN ANDREY ALEKSANDROVICH
IPC: E02B15/04
Filed: 2015-06-09
Abstract: The group of inventions relates to the field of organic chemistry and can be used for collecting films of petroleum, oils, mazut, fuels, hydrocarbons and other petroleum products with the aim of cleaning the surface of water, and also for cleaning water flows which have been contaminated by petroleum or petroleum products. A substance for collecting petroleum or petroleum products from the surface of water includes a natural polymer and additionally includes a biodegradable surfactant in the form of an aqueous solution with a concentration of no less than 0.1 g/L, and, as the natural polymer, contains polysaccharide microgels having a mass of between 20,000 and 200,000 Da and a particle size of between 50 and 600 nm in the form of an aqueous solution with a concentration of no less than 0.2 g/L, wherein the ratio of polysaccharide microgels to biodegradable surfactant is between 12:1 and 2:1. Methods for collecting petroleum or petroleum products from the surface of water include processing the surface of a film of petroleum or petroleum products using a reagent, and then collecting the product of the reaction thereof. The reagent consists in polysaccharide microgels having a mass of between 20,000 and 200,000 Da and a particle size of between 50 and 600 nm. According to a first variant, before or after spraying the reagent, a biodegradable surfactant is used for processing a film of petroleum or petroleum products, or a portion of said film; or, according to a second variant, the reagent is first mixed with the biodegradable surfactant until achieving a ratio of polysaccharide microgels to biodegradable surfactant of between 12:1 and 2:1. The technical result consists in decreasing the specific consumption of reagents used in the process of collecting petroleum or petroleum products from the surface of water, in enhancing the surfactant qualities of reagents, and also in reducing the residual amounts of said reagents in water.
Patent EA-032305-B1 (EA)
Title: Assembled product
Inventor: BRAENNSTROEM HANS
IPC: A47B61/00
Filed: 2014-09-15
Abstract: An assembled product includes at least three elements arranged in three different planes. A first element (1) is connected perpendicular to a second element (2), and a third element (4) is connected perpendicular to the second element. The assembled product includes one or more locking devices, each comprising a flexible tongue (30) arranged in an insertion groove (20) one of the at least three elements. The flexible tongue cooperates with a tongue groove (10), at an adjacent one of the at least three elements, for locking the one element and the adjacent element together. A second edge of the second element (2) is connected to a second edge of the third element (4) by a first of the locking devices.
Patent EA-034201-B1 (EA)
Title: Compounds as ror gamma modulators
Inventor: DAS SANJIB
IPC: C07D403/04
Filed: 2016-08-02
Abstract: The present invention relates to compounds of formula and pharmaceutically acceptable salts thereof, which are active as modulators of retinoid-related orphan receptor gamma t (RORγt). These compounds prevent, inhibit or suppress the action of RORγt and are therefore useful in the treatment of RORγt mediated diseases, disorders, syndromes or conditions such as, e.g., pain, inflammation, COPD, asthma, rheumatoid arthritis, colitis, multiple sclerosis, psoriasis, neurodegenerative diseases and cancer.
Patent EA-033946-B1 (EA)
Title: Method and apparatus for preheating and smelting manganese ore sinter
Inventor: KROGERUS HELGE
IPC: C22B47/00
Filed: 2016-11-23
Abstract: Described are a method and an apparatus for preheating and smelting manganese ore sinter. The method comprises feeding feed mixture (1) containing manganese ore sinter (2), reducing agent (3) and fluxing agent (4) into an submerged electric arc furnace (5), smelting feed mixture (1) to form a layer containing liquid manganese alloy and a layer containing slag, withdrawing liquid manganese and, discharging carbon monoxide containing carbonaceous gas (6), combusting carbon monoxide containing carbonaceous gas (6) in presence of oxygen such as air in a burner (7) to form carbon dioxide containing carbonaceous gas (9), and heating said feed mixture (1) in a pre-treatment silo (8) prior feeding said feed mixture (1) into the submerged electric arc furnace (5) with said carbon dioxide containing carbonaceous gas (9).
Patent EA-036139-B1 (EA)
Title: Method for producing 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)propan-2-ol
Inventor: GEBHARDT JOACHIM
IPC: C07D249/08
Filed: 2016-12-15
Abstract: The present invention relates to a method for producing 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)propan-2-ol in high purity. Especially it relates to a method in which this compound is effectively separated from its 1,2,4-triazol-4-yl isomer.
Patent EA-037913-B1 (EA)
Title: Process for treating organic waste or biomass
Inventor: VEZZANI MASSIMO
IPC: C02F11/13
Filed: 2017-11-08
Abstract: Provided is a process for treating organic waste or biomass comprising steps of: a) thermal pre-treatment of such organic waste or biomass, thus obtaining a pretreated organic material; b) anaerobic digestion of the pretreated organic material, with production of biogas and of a sludgy residue; c) separation of the sludgy residue into a liquid fraction and a solid fraction; d) stabilization of the solid fraction, where in step d) can be performed by steps of: i) providing a turbo-dryer (T'), with a heated inner wall (102), inside which there is rotatably supported a coaxial bladed rotor (107), ii) feeding a continuous flow of the solid fraction into the turbo-dryer; iii) centrifuging the continuous flow against the inner wall (102) of the turbo-dryer (T'), heated to a temperature of at least 180°C, towards the discharge opening (106); iv) discharging from the discharge opening a continuous flow of sanitized solid fraction and a continuous flow of water vapor.