baber/WOPTO huggingface dataset:
Patent CA-2515012-A1 (CA)
Title: Method of employing elevation of marinobufagenin in determining the presence of preeclampsia and related apparatus
Inventor: PUSCHETT JULES B
IPC: A61B/
Filed: 2004-02-02
Abstract: A method of determining the presence of preeclampsia is provided wherein a determination is made as to whether there has been a substantial elevation in marinobufagenin which may be a blood-derived or urine-derived and if such elevation does exist concluding that preeclampsia does exist in a patient. The method may advantageously be practiced by employing urine, blood serum or blood plasma as the body specimen containing the protein in determining whether a patient has preeclampsia. The method may include subsequent therapeutic patient treatment. Related diagnostic apparatus is also provided.
Patent CA-2516406-A1 (CA)
Inventor: MANN MICHAEL M
IPC: G06Q10/00
Filed: 2003-10-08
Abstract: La présente invention concerne un système et un procédé qui se servent des paramètres d'une entreprise et/ou de structures émergentes. Les groupes de mesures de paramètres d'entreprise peuvent comprendre, entre autres: la clarté, la participation, le levier d'exploitation, la priorité, la priorité relative, l'intégration. L'analyse de structures émergentes permet d'apporter des améliorations à un outil assisté par ordinateur pour permettre une meilleure analyse des processus de l'entreprise et une meilleure gestion des changements. Le système et le procédé de l'invention comprennent la collecte de données relatives aux motifs d'interaction parmi les personnes d'une organisation, l'analyse de ces relations par rapport aux processus et enjeux organisationnels spécifiques, et la présentation des résultats dans un format graphique utile pour la prise de décisions organisationnelles concernant la gestion des activités commerciales.
Patent CA-2516453-A1 (CA)
Title: Composition and methods for inhibiting cell survival
Inventor: BAUER JOSEPH A
IPC: A61K47/48
Filed: 2004-02-19
Abstract: The present invention is directed to compositions and methods of making and using compositions that are useful for treating cells or conditions caused or exacerbated by cell survival mechanisms of the body, particularly conditions exacerbated by cell survival mechanisms involving NF-KB. The compositions and methods of the present invention comprise a sensitizing agent or a chemopotentiating agent. In this regard, cobalamin drug conjugates and NO  donors act as chemopotentiating agents. Nitrosylcobalamin is particularly useful as a sensitizing or chemopotentiating agent, and methods utilizing nitrosylcobalamin prior to, simultaneous with and subsequent to radiation or chemotherapy are described, as are compositions which first release a nitrosylcobalamin compound or biologically active analog thereof, and then release the chemotherapeutic agent. Nitrosylcobalamin itself is a chemotherapeutic, and when administered in conjunction with other anti-cancer agents or techniques, a synergistic effect is seen.
Patent CA-2518792-A1 (CA)
Title: Methods and means to suppress symptoms of an allergic disease by inhibiting the glucocorticoid-induced tumor necrosis factor receptor (gitr or tnfrsf18)
Inventor: VAN OOSTERHOUT ANTONIUS JOSEPH
IPC: C07K16/28
Filed: 2004-03-25
Abstract: The invention relates to the field of immunology, more in particular to the field of immune therapy, even more particularly to a method for regulating tolerance to an allergen in a subject and even more specifically, to methods which involve regulation of a glucocorticoid-induced tumor necrosis factor receptor (GITR). The invention provides methods of treating allergic disorder and compositions for use therein.
Patent CA-2520697-A1 (CA)
Title: Erosion shielding for a circulating fluidized bed boiler
Inventor: KUUKKANEN KARI
IPC: F27D1/00
Filed: 2005-09-22
Abstract: A method for shielding the inner surface above the shield refractory (4) of the furnace wall (3) of a circulating fluidized bed boiler from erosion caused by suspension flows, in which method a shield structure is formed on the inner surface of the boiler wall. At least a first zone (1) and a second zone (2) are formed in the shield structure, the erosion-resistance properties of which zones differ from each other. In addition the invention relates to a circulating fluidized bed boiler, which comprises a corresponding shield structure.
Patent CA-2522358-A1 (CA)
Title: Precisely positioned nanowhiskers and nanowhisker arrays and method for preparing them
Inventor: SAMUELSON LARS IVAR
IPC: C30B11/12
Filed: 2004-01-07
Abstract: A nanoengineered structure comprising an array of more than about 1000 nanowhiskers on a substrate in a predetermined spatial configuration, for use for example as a photonic band gap array, wherein each nanowhisker is sited within a distance from a predetermined site not greater than about 20% of its distance from its nearest neighbour. To produce the array, an array of masses of a catalytic material are positioned on the surface, heat is applied and materials in gaseous form are introduced such as to create a catalytic seed particle from each mass, and to grow, from the catalytic seed particle, epitaxially, a nanowhisker of a predetermined material, and wherein each mass upon melting, retains approximately the same interface with the substrate surface such that forces causing the mass to migrate across said surface are less than a holding force across a wetted interface on the substrate surface.  A nanoengineered structure comprising an array of more than about 1000 nanowhiskers on a substrate in a predetermined spatial configuration, for use for example as a photonic band gap array, wherein each nanowhisker is sited within a distance from a predetermined site not greater than about 20% of its distance from its nearest neighbour. To produce the array, an array of masses of a catalytic material are positioned on the surface, heat is applied and materials in gaseous form are introduced such as to create a catalytic seed particle from each mass, and to grow, from the catalytic seed particle, epitaxially, a nanowhisker of a predetermined material, and wherein each mass upon melting, retains approximately the same interface with the substrate surface such that forces causing the mass to migrate across said surface are less than a holding force across a wetted interface on the substrate surface.
Patent CA-2524127-A1 (CA)
Title: Orthopedic fastener applicator
Inventor: SANDER THOMAS W
IPC: A61B17/88
Filed: 1994-06-02
Abstract: A kit for endoscopically applying an orthopedic fastener activated by a proximally moving setting pin. The kit including (a) means for drilling into bone; (b) an orthopedic fastener including a rivet portion and a setting pin movably disposed through the rivet portion, the setting pin having a proximal portion with an outer surface; (c) applicator means for applying the orthopedic fastener, the applicator including means for grasping the outer surface of the proximal portion of the setting pin; and (d) cannula means for receiving said drilling means and said applicator means.
Patent CA-2525811-A1 (CA)
Inventor: FRESE PETER
IPC: B05D7/00
Filed: 2004-05-14
Abstract: A multi-layer coating for coating a substrate surface, comprising at least one color-imparting layer, which contains three-dimensional photonic crystals as effect-imparting interference pigments.
Patent CA-2526912-A1 (CA)
Title: Method for producing formic acid formiates
Inventor: LENZ ROBERT
IPC: C07C53/02
Filed: 2004-05-14
Abstract: The invention relates to a method for producing formic acid formiates consisting in supplying a formic acid-containing fluid flow (I) and a metal formiate-containing fluid flow (II) and in mixing the fluid flow (I) and the fluid flow (II) in order to obtain corresponding formic acid formiate. Said invention is characterised in that a fluid flow (III) containing metallic formiate components, metal methanolate, methanol and formic acid methylester (MeFo) at a ratio > 0.1 mass % is inserted into the fluid flow (I) or the precursor thereof, into the fluid flow (II) or the precursor thereof or into a mixture which is formed by the fluid flows (I) and (II). Said fluid flow (III) is obtained by a method for producing MeFo by carbonylating methanol in a reactor at a pressure up to 50 MPa absolutes in the presence of metal methanolate which used as homogenous catalyst.
Patent CA-2530234-A1 (CA)
Inventor: TU HOSHENG
IPC: A61F2/82
Filed: 2004-08-03
Abstract: L'invention concerne des prothèses intraoculaires (229) et des applicateurs destinés au traitement de glaucomes. Lesdites prothèses (229) sont conçues pour s'étendre entre la chambre antérieure de l'oeil et le canal de Schlemm (22) afin d'améliorer l'écoulement d'humeur aqueuse à partir de la chambre antérieure (20) de manière à réduire la pression intraoculaire. Lesdites prothèses (229) peuvent présenter des éléments permettant l'ancrage de la prothèse dans le canal de Schlemm (22) et permettant d'empêcher que les parois du canal de Schlemm (22) ne ferment la sortie des prothèses (229). Lesdits applicateurs peuvent être orientables de manière à rendre l'implantation plus facile. En outre, les applicateurs peuvent être conçus pour retenir une pluralité de prothèses de sorte que de multiples prothèses peuvent être implantées à travers une incision sans enlever l'applicateur de l'incision entre des implantations en série.
Patent CA-2531006-A1 (CA)
Inventor: CLAYDON PAUL CHARLES
IPC: B65D79/00
Filed: 2004-06-22
Abstract: A closure for a food can including a foil end panel (1) bonded to an intermediate ring (5) which is fixed to the can body. The foil panel (1) comprises a diaphragm having a centre panel which included at least one concentric bead. The profile of this beaded panel is selected so that its downward position is no greater than the lowest point of the intermediate ring. The provision of the bead(s) reduces pressure differences experienced by the diaphragm, particularly during processing of the can contents, due to the volume increase available from the beads.
Patent CA-2532346-A1 (CA)
Inventor: JAWAID ABRAR
IPC: B27N3/00
Filed: 2004-07-16
Abstract: A method of recovering a constituent of a board material comprised of a matrix of adhesively bonded lignocellulosic elements, the method comprising subjecting the material to a combination of (i) electromagnetic radiation and (ii) soaking or immersion in a liquid medium, and recovering the constituent.
Patent CA-2532667-A1 (CA)
Title: Semi-solid formulations for the oral administration of taxoids
Inventor: PERACCHIA MARIA-TERESA
IPC: A61K31/337
Filed: 2004-07-15
Abstract: Semi-solid formulations for the oral administration of taxoids. The present invention relates to novel formulations of taxoids for oral administration.
Patent CA-2533734-A1 (CA)
Title: Window shade
Inventor: STRAND TORALF H
IPC: A47H5/02
Filed: 2006-01-24
Abstract: A window curtain assembly is disclosed. The window curtain assembly includes a headrail, take up member, a pair of panels affixed to the headrail, and a gair of lift cords attached to the take up member and each panel. Rotation of the take up member winds the lift cords around the take up member moving the panels upwardly and away from each other to open the curtain.
Patent CA-2536319-A1 (CA)
Title: Amorphous, spray-dried powders having a reduced moisture content and a high-long term stability
Inventor: SCHUELE STEFANIE
IPC: A61K47/00
Filed: 2004-08-20
Abstract: The invention relates to spray-dried amorphous powders, which contain a pharmaceutical active ingredient and a matrix-forming agent, preferably a polymer, a sugar or a sugar alcohol of = 20-60 % (w/w). The inventive powders have a moisture content that is less than 1.2 % (w/w), preferably less than 1 % (w/w). The invention also relates to specific methods for producing said powders and to methods for administering the powders by inhalation.
Patent CA-2536535-A1 (CA)
Title: Compounds and compositions as protein kinase inhibitors
Inventor: GRAY NATHANAEL SCHIANDER
IPC: C07D487/02
Filed: 2004-08-27
Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, BCR-Abl, Bmx, CSK, TrkB, FGFR3, Fes, Lck, B-RAF, C-RAF, MKK6, SAPK2.alpha. and SAPK2.beta. kinases.
Patent CA-2538251-A1 (CA)
Inventor: DOLSON JENNIFER SHIRRIFF
IPC: A47B81/00
Filed: 2004-09-10
Abstract: A portable storage unit to carry, store and organize, various sports sticks, garden tools and other household items that require upright storage either on a permanent or temporary basis consisting of a pair of rigid side members that in the open position are spaced apart and a support section provided between the two side members, the support section adapted to permit the side members to move from an open spaced apart position to a closed adjacent position to permit the portable storage unit to be carried in one hand.
Patent CA-2538524-A1 (CA)
Title: Appareil electromagnetique et methode de commande du debit de fluides
Inventor: HERBERT KAY
IPC: H01F7/08
Filed: 2006-03-06
Abstract: Un actionneur comprend une base d'actionneur, une bobine et une pièce de perche formant une pochette pour une armature ferromagnétique située à l'intérieur de l'actionneur. L'actionneur comprend un aimant radial et une bobine de solénoïde. La bobine de solénoïde est construite et arrangée pour entraîner un déplacement linéaire de l'armature à l'application d'un courant dû à la bobine provenant d'un circuit de commande. L'actionneur peut comprendre une membrane souple qui comprend partiellement l'armature pour former une chambre d'armature remplie d'un fluide incompressible. Dans un modèle de vanne, un écoulement de fluide est arrêté en amenant l'armature en position déployée de sorte que la membrane s'appuie contre le siège de vanne. L'écoulement de fluide est ouvert en éloignant l'armature et la membrane du siège de vanne en position rétractée.
Patent CA-2540542-A1 (CA)
Title: Molecular sieve catalyst composition, its making and use in conversion processes
Inventor: HU WEIGUO
IPC: B01J29/06
Filed: 2004-08-16
Abstract: This invention provides methods of making molecular sieve catalyst particles, molecular sieve slurries that can be used in such methods, molecular sieve catalyst compositions and their use in catalytic hydrocarbon conversion processes. In one of its aspects, the invention provides a method of making molecular sieve catalyst particles, the method comprising the steps of: a) providing a solution or suspension of an aluminum-containing inorganic oxide precursor in a liquid medium; b) combining the solution or suspension of aluminum-containing inorganic oxide precursor with a molecular sieve, and optionally other formulating agents, to form a catalyst formulation slurry; c) aging the catalyst formulation slurry to generate in said slurry a percentage, or increase in said slurry the existing percentage, of aluminum atoms of the aluminum-containing precursor in the form of oligomers having a sharp 27 Al NMR peak at 62-63 ppm; and d) forming molecular sieve catalyst particles from the catalyst formulation slurry. The catalyst compositions obtained by the methods of the present invention have improved attrition resistance, and are particularly useful in hydrocarbon conversion processes.
Patent CA-2541189-A1 (CA)
Title: Methods to identify evolutionarily significant changes in polynucleotide and polypeptide sequences in prokaryotes
Inventor: MESSIER WALTER
IPC: G16B20/50
Filed: 2004-10-01
Abstract: Methods for identifying polynucleotide and polypeptide sequences which may be associated with commercially relevant or useful traits in prokaryotes are provided. The methods employ comparison of homologous genes from two closely related prokaryote species to identify evolutionarily significant changes.  Sequences thus identified may be useful in developing therapeutics, diagnostics, or vaccines.
Patent CA-2544186-A1 (CA)
Title: Inhibition of fgfr3 and treatment of multiple myeloma with benzimidazole quinolinones
Inventor: SHANG XIAO
IPC: A61K31/4709
Filed: 2004-11-05
Abstract: Methods of inhibiting fibroblast growth factor receptor 3 and treating various conditions mediated by fibroblast growth factor receptor 3 are provided that include administering to a subject a compound of Structure I, a pharmaceutically acceptable salt thereof, a tautomer thereof, or a pharmaceutically acceptable salt of the tautomer. Compounds having the Structure I have the following structure where and have the variables described herein. Such compounds may be used to prepare medicaments for use in inhibiting fibroblast growth factor receptor 3 and for use in treating conditions mediated by fibroblast growth factor receptor 3 such as multiple myeloma.
Patent CA-2544664-A1 (CA)
Title: Safety device for an elevator
Inventor: HIGASHINAKA TSUNEHIRO
IPC: B66B5/18
Filed: 2004-05-25
Abstract: An emergency stop device of an elevator, wherein a pair of rotating levers are rotatably fitted to a car. A plurality of wedges allowed to come into contact with and separate from a car guide rail by the rotation of rotating members are fitted to the rotating members. The rotating levers are connected to each other through connection members. An electromagnetic actuator reciprocatingly displacing the connection members so as to rotate the rotating levers in a direction for bringing the wedges into contact with and separating them from the car guide rail is mounted on the car. The electromagnetic actuator is operated by operating signals inputted therein from an output part mounted on a control panel.
Patent CA-2545942-A1 (CA)
Title: Aryl imidazoles and their use as anti-cancer agents
Inventor: YOUNG AIPING H
IPC: A61K31/4164
Filed: 2004-11-15
Abstract: Therapeutically effective 2,4,5-trisubstituted imidazole compounds are provided.  Also provided are methods -of preparing the compounds and pharmaceutical compo-sitions comprising the compounds alone or in combination with other agents. The present invention further provides for the use of the compounds as anti-cancer agents;  wherein: R1 is aryl, substituted aryl, heterocycle, substituted heterocycle, heteroaryl, substituted heteroaryl or amino; R2 and R3 are independently aryl, substituted aryl, heterocycle, heteroaryl, substituted heterocycle, or substituted heteroaryl or R2 and R3 when taken together along with the carbon atoms they are attached to, form aryl or substituted aryl, and R4 is hydrogen, halogen, hydroxyl, thiol, lower alkyl, substituted lower alkyl, lower alkenyl, substituted lower alkenyl, lower alkynyl, substituted lower alkynyl, alkylalkenyl, alkyl alkynyl, alkoxy, alkyithio, aryl, aryloxy, amino, amido, carboxyl, aryl, substituted aryl, heterocycle, heteroaryl, substituted heterocycle, heteroalkyl, cycloalkyl, substituted cycloalkyl, alkylcycloalkyl, alkylcyclobeteroalkyl, nitro, cyano or -S(O)o.2R wherein R is alkyl, substituted alkyl, aryl, substituted aryl, heterocycle, beteroaryl, substituted heterocycle, or substituted heteroaryl.
Patent CA-2547070-A1 (CA)
Inventor: BILLARANT FABRICE
IPC: B29C39/10
Filed: 2006-05-15
Abstract: Surmoulé, comportant une base ayant une partie centrale, d'une première face de laquelle sont issus des crochets formant partie mâle d'un auto agrippant ; deux parties formant lisières, latéralement de part et d'autre de la partie centrale ; et des moyens magnétiques pouvant coopérer avec un aimant pour attirer le surmoulé, est caractérisé en ce que les lisières comportent chacune au moins deux nervures, de préférence au moins trois ou quatre nervures, qui font saillie des lisières du même côté de la base que l es crochets.
Patent CA-2547098-A1 (CA)
Title: Cannulated fastener system
Inventor: MURRAY STEVEN F
IPC: A61B17/56
Filed: 2004-11-24
Abstract: A cannulated fastener system is provided for orthopedic applications that include attaching bone plates to bone. The bone fastener has a cannulation with an inner shape. One or more screwdrivers is provided with a shaft having a shape that matches the cannulation of the fastener to rotationally fix the fastener to the screwdriver. In addition, the screwdrivers have a cutting blade that begins the drilling of a hole for the bone fastener. The screwdrivers may either be for use with a single fastener or have multiple fasteners loaded within a retaining sleeve for automatic or controlled dispensing.
Patent CA-2548549-A1 (CA)
Title: High tenacity nanocomposite and method for producing the same
Inventor: KUO WEN-FAA
IPC: C01B33/44
Filed: 2006-05-26
Abstract: The present invention relates to a nanocomposite material, which comprises bedded clay modified by alkyl amino salt with long chain and a silicone compound with functional group, then mix with a polymer compound. The present invention has a high rigidity and tenacity by inserting the polymer compound into the layers of the modified clay.
Patent CA-2549086-A1 (CA)
Inventor: DESPRES PHILIPPE
IPC: A61K38/17
Filed: 2006-06-20
Abstract: La présente invention concerne la construction d'un polypeptide chimérique utile dans la prévention ou dans le traitement d'une infection à Flaviviridae. La présente invention porte également sur l'utilisation du polypeptide chimérique dans l'élaboration de vecteurs viraux recombinants, tel un vecteu r viral vivant rougeole.
Patent CA-2553791-A1 (CA)
Title: Handheld breath tester housing and mouthpiece
Inventor: FORRESTER RANKINE M
IPC: A61B5/097
Filed: 2004-07-27
Abstract: A breath tester housing assembly (10) is provided. The assembly comprises a housing having a base (28) to be gripped by an operator, a display (72) oriented to be in line with an operator's direct line of view while gripping the base, and a mouthpiece interface (16) for interfacing with a removable mouthpiece (12) so that when a subject blows into the mouthpiece, the displa y is not in the direct line of view of the subject. The assembly further comprises a mouthpiece for engaging to the mouthpiece interface. The mouthpiece comprises a body having a substantially planar surface.
Patent CA-2554932-A1 (CA)
Title: Solvent extraction of lipids such as essential fatty acids
Inventor: LAU ANDRE KA-CHUN
IPC: A61K35/618
Filed: 2005-01-28
Abstract: Lipids (including fatty acids) are extracted from animal solids such as powdered, freeze dried or fresh meat of green lipped mussel (Perna canaliculus) by mixing said solids with a solvent such as acetone capable of dissolving lipids therefrom to form a solvent extract, removing solvent from said extract by nanofiltration to produce a concentrated lipid extract and recovered solvent, and removing further solvent from the concentrated extract by rotary evaporation to leave extracted lipids particularly rich in eicosatetraenoic acids (ETA~s).
Patent CA-2557234-A1 (CA)
Inventor: CUNHA FRANK
IPC: F01D5/20
Filed: 2006-08-25
Abstract: A method for manufacturing a cooling microcircuit in a blade-outer-air-seal is provided. The method broadly comprises the steps of forming a first section of the blade-outer-air-seal having a first exposed internal wall, forming a second section of the blade-outer-air-seal having a second exposed internal wall, and forming at least one cooling microcircuit on at least one of the first and second exposed internal walls.
Patent CA-2560731-A1 (CA)
Inventor: TUNG WAE-HAI
IPC: D02J13/00
Filed: 2005-04-04
Abstract: An apparatus and method for texture heat-setting bulk continuous filament (BCF) yarns in hot air heat-setting machines that includes a preheating device/step that in the processing of BCF yarns. The apparatus and method use a mixture of steam and atmospheric air to preheat a twisted BCF yarn bundle to develop crimp memory and provide cohesion to the twisted BCF yarn bundle. Yarn bundle cohesion during texture heat-setting helps to avoid frequent breaks at the winder of the hot air heat-setting machine. The addition of the preheating device/step significantly improves the ability of hot air heat-setting machines to maintain continuous operation during texture setting of BCF yarns and makes the hot air heat-setting method commercially viable for this application.