baber/WOPTO huggingface dataset:
Patent UA-19041-A (UA)
Title: Elongated tillage implement and its working tool
IPC: A01B21/04
Filed: 1987-06-26
Abstract: An elongated ground working tool adapted to be supported at each end to rotate about the longitudinal axis thereof, said tool including a multitude of tool elements arranged in a plurality of groups in the longitudinal direction of the tool, each group of tool elements inter-engaging with the next adjacent group to form flexible connections between the groups that will permit tensioning of the tool in the longitudinal direction when supported for rotation, said tool elements being adapted so that when the groups of tool elements are inter-engaged and the tool longitudinally tensioned, each group of tool elements presents a plurality of prongs spaced about and projecting outwardly with respect to the longitudinal axis of the tool and wherein each tool element includes a portion extending generally in said longitudinal direction, one prong from each of two tool elements of one group extending through an opening or respective openings in said longitudinal portion of a tool element of the next adjacent group, each prong in said one group of tool elements extending through a respective longitudinal portion of a tool element of the next adjacent group of tool elements to provide the flexible connection between the groups of tool elements.
Patent UA-18250-A (UA)
Title: Method for preparing composition intended for treating parasitic diseases of animals
IPC: A61K47/44
Filed: 1990-04-11
Abstract: A method for preparing the composition intended for treating the parasitic diseases of the animals has been proposed. 25-Cyclohexylvermectine B1 is used as an active ingredient, and the sesame oil based composition is used as a solvent. The invention relates to agriculture, namely to the veterinary pharmacology.
Patent UA-24057-A (UA)
Title: Vertical partition
Inventor: KHANYK YAROSLAV MYKOLAIOVYCH
Filed: 1990-05-15
Abstract: A vertical partition of compartments between conveyor and the body of drying chamber has plate with roller placed from the side of conveyor and with mechanism of vertical displacement. In the plate a window with gate is additionally provided, and mechanism of vertical displacement is arranged as spring-loaded screw pair.
Patent BG-103555-A (BG)
Title: System for lifting and lowering of fluid tank lining
Inventor: MCROBERT IAN
IPC: E04H4/14
Filed: 1999-07-06
Abstract: The system is used in the water treatment engineering, in particular for cleaning of reservoirs and water basins. It guarantees access to the reservoir without any need for emptying it. The system (10) for lifting and lowering of lining (12) of a swimming pool (14) includes a slab (22) used for a specifyingd a place for discharge (24) for making a fluid connection between the external surface (26) of the lining (12) and the internal surface (16) of the swimming pool (14). Lining (12) is separated from the surface (16) of the swimming pool in the area behind the plate (16) of the basin in the slab (22) and is fitted a second time along the upper edge (28) of the slab (22) by means of an ordinary fixing bar (20). Pipe (30) has a section (30') which continues along its rear side (back) (32) of slab (22), under the upper edge (28) Holes (34) cut in the slab ensure the connection to section (30) . Pipe (36) with section (36') gets along the rear side (32), close to its lower edge in order to ensure air to the place for discharge (24). Section (36') is supplied with a certain number of holes (40) for access of air to the place of discharge (24). In order to lift the lining (12) air is supplied across pipes (30, 30') to its external surface (26). The air gradually lifts the lining upwards at some distance from the surface (16), displacing the water held in the pool (14) so that it will run along the upper edge (28) at the place for the discharge (24) so that the water will find its place under the surface (26). In this way lining (12) is gradually lifted up to its final fitting above the water level. To return the lining (12) to its facing position air is supplied across pipes (30, 36) at the place of discharging (24) When the air penetrates in, it carries the water to the place of discharge (24) and above the upper edge (28) on the interior surface of lining (12) in order to submerge it back to its facing position. 13 claims, 9 figures
Patent BG-104280-A (BG)
Title: Device for the treatment and distributuion of water
Inventor: WISEBURGH PETER
IPC: C02F1/44
Filed: 2000-03-29
Abstract: The device contains a supporting housing and an energy source, inlet hole for untreated water and outlet hole for the distribution of the treated water, replaceable filter (50) with filter layers in depth and microporous diaphragm device fitted between the inlet and outlet hole, a device for moving the water across the filter at constant speed of the flow, device for registering the time from the installment of the filter and the control device with a desired accuracy of the amount of water which has gone across the filter. In addition it contains a device controlling the permanency of the flow, and a device for warning the consumer when the recorded data of the print- out and/or the controlling device have reached a certain threshold value or the highest one of the multiplicity of the respective threshold values. 38 claims, 16 figures
Patent BG-107603-A (BG)
Title: Tartarate salts of thiazolidinedione derivative
Inventor: CHOUDARY BERNADETTE M
IPC: A61P3/10
Filed: 2003-02-28
Abstract: A novel pharmaceutical compound 5-[4-2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4 -dione L(+) Tartarate or a solvate thereof, a process for preparing such a compound, a pharmaceutical composition comprising such a compound and the use of such a compound in medicine. 11 claims, 4 figures
Patent BG-112724-A (BG)
Title: Ballista-crossbow for projectile launch
Inventor: DIMITROV DIMITAR
IPC: F41B5/14
Filed: 2018-04-24
Abstract: The invention has the elements specific for the crossbow and other additional ones. It is designed for crossbow shooting sports enthusiasts, as well as it offers cheaper and reusable ammunition. Solves the problem with the high cost of arrows and their rapid depreciation by replacing them with special projectiles. The design allows for automatic positioning of the projectile, which reduces the time between the shots.
Patent CN-1265990-A (CN)
Title: 多功能安全警示器
Inventor: WANG QINGYONG
IPC: B60Q1/52
Filed: 2000-04-14
Abstract: 一种多功能安全警示器,在警示器中央设有一光棒区,该光棒区两端设有左、右指示灯,并通过一控制回路与车辆线路连接。若车辆故障警示灯闪动时,拨动车辆方向灯开关,使安全警示灯左侧或右侧灯随之闪动,以提醒后方本车辆的动向。若启动安全警示器警示灯,车辆方向指示灯亦能使后方明白车辆的动向,能有效发挥警示作用并兼具告知本车动向的功能,以提高行车安全。
Patent CN-1287290-A (CN)
Inventor: MORI WATANABE
IPC: H02K7/14
Filed: 2000-09-06
Abstract: 一用于构成电子表变换器的线圈组件保护结构是这样实现的,即它包括一个用于覆盖线圈组件之上表面的膜件及一用于夹持该膜件的夹持装置。
Patent CN-1413359-A (CN)
Title: 检测光刻胶剥离过程终点的方法和装置
Inventor: TUQIANG NI
IPC: H01L21/3065
Filed: 2000-12-19
Abstract: 一种用来检测光刻胶剥离过程的终点的方法和装置。要剥离光刻胶的晶片被设置在剥离室内。在基本上所有的光刻胶都从晶片上剥离后，O和NO反应形成NO 2 的速度增加，这就增加了发射光的强度。一个光检测装置检测到光强度的增加，这标志着光刻胶剥离过程的终点。
Patent CN-1410870-A (CN)
Title: 软木鼠标垫及其制作方法
Inventor: XU SHIHAO
IPC: B29C43/00
Filed: 2001-09-24
Abstract: 本发明公开了一种软木鼠标垫及其制作方法，其工艺过程是：先将软木树皮剥下来，清除杂质，切碎成所需的颗粒，与树脂胶混合，搅拌均匀倒入型模，在高温高压下挤压成型，然后切割成所需厚度的板片，再裁切成所需的形状，经高温高压小水雾下的软化烫平去毛处理，即成软木鼠标垫。该产品具有足够强度和硬度，表面有大量孔隙显粗造，能刮存鼠标内的滚轮上的灰尘，鼠标不会沉陷于垫内，反而可获得高灵敏度的顺畅滑动，并可延长鼠标的使用寿命。
Patent CN-1458305-A (CN)
Title: 一种ZnO纳米晶须材料及其制备方法
Inventor: WU RUN
IPC: C01G9/03
Filed: 2002-05-13
Abstract: 本发明涉及一种用汽相法从冶金含锌废弃物中生产ZnO纳米晶须的方法。其方法是以冶金含锌废弃物为原料，富集后再放入真空蒸发室加热，当Zn蒸气焰喷出时，用高速细流的惰性气体将此气焰导入反应室，进行纳米氧化锌的合成。本发明能方便地对ZnO纳米粒子的形态进行控制，团聚成块少，易收集，易实现工业化，成本低，对环境无污染。其制品既可在光催化中能有效地降解有毒物质，又能增强材料表面对激光光能的吸收。
Patent CN-1464737-A (CN)
Inventor: ZENG RENSHOU
IPC: H04N1/028
Filed: 2002-06-27
Abstract: 一种具有多种像素尺寸的图像传感器，应用在一图像撷取设备如扫描器中，图像传感器至少包括一红色传感阵列、一绿色传感阵列、及一蓝色传感阵列，分别由n个红、绿、蓝色传感格点线性排列而成。其中，红色传感阵列的总长等于绿色传感阵列的总长等于蓝色传感阵列的总长。为了补偿边缘感光不足的缺点，使每一传感阵列中的传感格点面积自中心向两侧渐渐增加。为了平衡红、蓝、绿三色之间敏锐度的差异，则使敏锐度较好的绿色传感格点面积略减，或是使敏锐度较差的蓝色传感格点面积略增。
Patent CN-1402979-A (CN)
Title: 取代苯基五元氮杂环类除草剂
Inventor: ZHOU YUHAN
IPC: C07D231/12
Filed: 2002-09-28
Abstract: 本发明提供了一类取代苯基五元氮杂环吡唑或异噁唑结构的除草剂，即在苯环上，1－位连接的氮杂环是吡唑或异噁唑衍生物，2，4－位碳原子上的氢原子分别被氟原子、氯原子取代，5－位上连接不同的取代基。对合成的化合物分别测定了它们的熔点，并对其结构通过MS和′H－NMR确认。除草剂对禾本科杂草稗草、狗尾草和阔叶杂草苘麻、苋菜进行了除草活性测试，获得很好的效果。
Patent CN-1504442-A (CN)
Inventor: LIU XUEBIN
IPC: C01B32/40
Filed: 2002-11-29
Abstract: 一种烃类气相氧化裂解制低碳烯烃并联产一氧化碳的方法。它将原料烃类汽化后与氧气或空气混合，在600～950℃温度下，进行烃类氧化裂解反应，其中原料气中C/O摩尔比为1.5～6.0。本发明借助于氧的作用，改变了烃类裂解反应的热力学体系，使得烃类脱氢形成烷基自由基过程的活化能大大降低，改变了反应过程，提高了烃类的转化率和反应速度，在较低温度下，不仅使链烷烃裂解生成低碳烯烃，而且使环烷烃开环裂解生成低碳烯烃，提高了烯烃产率；另外，通过控制产物分布，使得氧化反应选择性地生成CO而少产CO 2 ；同常规烃类热裂解工艺相比，本发明具有能耗低、排放少、积炭微、生产能力高、生产成本低和投资省的优点。
Patent CN-1413803-A (CN)
Title: 矩形平板的倒角加工方法及装置
Inventor: TAKASHI KAWATE
IPC: B24B9/00
Filed: 2002-10-21
Abstract: 目的在于提供一种可降低加工成本、并且可提高加工精度的矩形平板的倒角加工方法。将封装盖用的玻璃板层叠而成的层叠体8和研磨材料封入管子10内，通过使层叠体8在管子10的内壁上进行滑动运动，来进行层叠体8的倒角加工。管子10的半径设成满足(1)式的半径R或接近该值的半径。式中，L为玻璃板的长边的长度(mm)，r为玻璃板的长边上的倒角部分的长度与短边上的倒角部分的长度之比率。
Patent CN-1508512-A (CN)
Inventor: ZHANG GUANGJUN
IPC: G01B11/24
Filed: 2002-12-17
Abstract: 本发明属于测量技术领域，涉及对结构光三维视觉检测中传感器标定方法的改进。本发明的步骤是：系统构建－采集标定点－选定坐标系－安放靶－采集靶标图像－计算特征点的三维物坐标－提取特征点的二维像坐标－重复提取特征点坐标－标定传感器－存储标定结果。本发明有利于提高整个视觉检测系统的精度，减少由于坐标系转换所带来的精度损失。
Patent CN-1735421-A (CN)
Inventor: YAOHUA CHEN XIAOZHANG GOU YULI
IPC: A61K36/06
Filed: 2002-12-04
Abstract: 本发明公开了一种新的治疗妇女更年期综合症的药物，它由包含人参、当归、黄芪、麦冬、女贞子、白术、白芍、茯苓、黄柏、川芎、甘草、柴胡、熟地、淫羊藿、薄荷、仙茅、知母和墨旱莲的原料，经炮制，蒸煮，干燥，磨粉，并且在药粉中加入一定量的水和蜂蜜制成水蜜丸而成。
Patent CN-1536079-A (CN)
Inventor: ZHANG WENBO
IPC: A61K38/46
Filed: 2003-04-09
Abstract: 本发明涉及一种没有连接基团的修饰的精氨酸脱亚氨酶，即式(I)结构的化合物：ADI－(PEG)n (I)；其中PEG表示平均分子量为1000－20000Da的聚乙二醇，而ADI表示精氨酸脱亚氨酶，而“－”表示PEG和ADI之间的共价键，n为2－30的整数。本发明还提供了具有该修饰的精氨酸脱亚氨酶的制法和相应的药物组合物。本发明的化合物具有更为优异的综合特性，即出色的抗肿瘤效果，化学性质更稳定、免疫原性更低。
Patent CN-1526981-A (CN)
Inventor: YANG JIAN AN
IPC: F16L9/147
Filed: 2003-09-23
Abstract: 本发明涉及一种水力输送煤灰渣、矿砂、泥沙等固体颗粒的耐磨、耐腐、抗结垢的金属丝网增强超高分子量聚乙烯玻璃钢复合管道，它由外壳和内衬组成，其特点是：内衬是由金属丝网通过热压至高分子材料中所形成，外壳为玻璃钢，由金属丝网增强的内衬通过暴露在其外表面具有一定厚度的金属丝网用环氧树脂粘结剂与玻璃钢外壳的内表面实行粘结连接，解决了作内衬的高分子材料与玻璃钢外壳的难以粘结的问题。使本发明既有玻璃钢管道固有的轻质、高强、耐腐的优点，而且又有内衬高分子材料耐磨、耐腐、抗结垢的优良特性，可以用作耐腐、耐磨、抗结垢的水力输送固体颗粒的特种管道。
Patent CN-1571464-A (CN)
Title: 一种ip电话与电话网的无缝通讯方法
Inventor: CHEN CHANGZHENG
IPC: H04L12/66
Filed: 2003-07-17
Abstract: 本发明涉及计算机网络通讯技术领域中的IP电话与电话网的无缝通讯方法。主要步骤为：与远端的用户进行通话，向远端的网关发送通话请求；网关解析目标终端类型，如果通话双方是IP终端，则主要是负责协商通话参数，然后由双方完成后续的通话过程，如果目标终端是固定电话，则由网关进行相应的模拟和数字信号的转换，并协助完成后续的通话过程；网关接收到IP终端或者电话网中的挂断信号，释放通话资源，并结束通话。主要优点：充分利用网络资源，能够在同一条线路上传输比采用模拟技术时更多的呼叫，大大提高了效率。方便易用，通话条件不受限制。
Patent CN-1653680-A (CN)
Inventor: NAOKI SUGANO
IPC: H02P29/00
Filed: 2003-04-23
Abstract: 在一种建筑机械中包括用于驱动转动系统的电动马达(6)、指挥电动马达(6)操作的操作部件、和按照从操作部件来的操作指令控制电动马达(6)的控制器(9)，控制器(9)有实时仿真液压转动驱动装置动态特征的仿真模型(9a)，和控制目标值是按照从操作部件来的操作指令由仿真模型(9a)计算得出用于控制电动马达(6)。因此，电动马达可以缓和地响应杆在中间区的操作，和迅速响应杆的快速操作。
Patent CN-1659883-A (CN)
Inventor: HONDA SHING
IPC: H04N7/173
Filed: 2003-04-01
Abstract: 本发明提供用来远程播放DVD的方法与系统的技术。在一实施例中，一远程播放系统的某些组件是属于在至少一客户端装置上执行的一DVD播放器软件，而其它组件是位于至少一服务器装置上。DVD控制与浏览命令以及演播资料是在客户端与服务器端之间传递。因此使用者可利用位于任意位置的客户端装置上的DVD光驱来控制、浏览以及播放来自一服务器装置的DVD演播资料，只要客户端是经由网络连接至服务器。
Patent CN-1701076-A (CN)
Inventor: DAHUI STACK GARY PAUL ZHOU
IPC: C07D491/04
Filed: 2003-09-11
Abstract: 通式化合物，该化合物用于治疗抑郁症(非限定性地包括重性抑郁疾病、儿童抑郁症和情绪不良)、焦虑、恐慌症、创伤后精神紧张性障碍、月经前烦躁症(也称为月经前综合症)、注意涣散障碍(伴有和不伴有多动症)、强迫性神经官能症、社交恐惧症、泛化性焦虑症、肥胖、饮食疾病如神经性厌食症和神经性贪食症、血管舒缩潮红、可卡因和酒瘾、性机能障碍以及相关疾病。
Patent CN-1695099-A (CN)
Inventor: DANA RIBARICH THOMAS WILHELM
IPC: G05F1/00
Filed: 2003-09-19
Abstract: 一种电子镇流器提供了用于过电流保护和半桥硬切换的故障检测和安全特性。根据可操作的反馈参数，压控振荡器提供可变化的切换频率。为了自适应地调整压控振荡器的频率，反馈电路读出负载电流并输出电压，以判断故障条件和提供控制信息。通过适当地控制压控振荡器输出，电子镇流器保持具有最小电流切换的零电压切换，以获得高效的且稳固的电子镇流器控制。整个控制集成在单片集成电路上。
Patent CN-1717749-A (CN)
Inventor: SUNG-WEI MOON NATHAN I EGUCHI
IPC: H04L1/22
Filed: 2003-09-30
Abstract: 使用预分配冗余(PAR)体系结构自修复非易失性存储器的方法及装置。在代表性实施方案中，非易失性存储器包括块、存储子块、具有与存储子块的容量相等容量的冗余子块、连接到块的比较器(265)、连接到块的故障锁存电路(270)，以及连接到块的熔丝(260)。比较器(265)被配置以通过比较期望数据与读出数据识别特定存储子块中的故障。故障锁存电路(270)被配置以确定特定存储子块的地址。熔丝并配置以使特定存储子块用冗余子块替换从而修复非易失性存储器。
Patent CN-85101580-A (CN)
IPC: C07C47/26
Filed: 1985-04-01
Abstract: 本发明提供一种制备式I(4-苯基-1，3-二氧六环-顺-5-一价基)链烯酸新方法。本方法涉及式II的醛与内盐反应得到式III的赤二醇，然后将赤二醇环化成式I所要求的二氧六环衍生物。本发明还提供了一种由式IIa相应的邻位羟基内醚制备式II的醛之新方法，式IIa的邻位羟基内醚是由式V的反式苯基仲康酸通过两步选择还原反应得到的，它们本身具有反式立体化学结构。式I的化合物用作为有效的治疗剂。
Patent CN-1052591-A (CN)
Inventor: DYKSTRA SIEBERN
IPC: A01N25/10
Filed: 1990-11-29
Abstract: 本发明公开了一种水凝胶体昆虫毒饵。这种胶
体昆虫毒饵包括水，杀中心活性成分和可引起水和杀
虫活性成分形成凝胶体的有效量的鹿角菜。鹿角菜
成分可以引诱昆虫到昆虫毒饵上取食毒饵。
Patent CN-1055609-A (CN)
Inventor: CHEN GWENDYLINE Y Y T
IPC: G03F3/10
Filed: 1991-04-10
Abstract: 公开了一种适于制备着色影像的光敏元件。该
光敏元件包含：一个光致可溶层，它基本上由一种酸
不稳定聚合物和一种光致加溶剂组成；一个弹性体
层；和一个支撑体。它可以用含水溶剂，最好是普通
自来水加工。
Patent CN-1071926-A (CN)
Title: 新的嘧啶并[1′，6′：1，2]吡啶并[3，4-b]吲哚衍生物，含有它们的药物组合物及其制备方法
Inventor: DOMANY GYORGY
IPC: C07D471/04
Filed: 1992-10-23
Abstract: 本发明涉及新的式I的嘧啶并[1′，6′：1，2]吡啶
并[3，4-b]吲哚衍生物的制备方法。
   
     式中R代表C 1-4 烷基或任选的取代的芳基-(C 1-4 
烷基)或任选的取代的芳基；A和B代表α-位氢，或
A和B共同构成一个化学键。
Patent CN-1093870-A (CN)
Title: 制作多层饼干的方法及设备
Inventor: BEER RICHARD
IPC: A21B1/48
Filed: 1993-12-14
Abstract: 本发明涉及一种多层饼干的生产方法。首先将
未经烘烤的单层生面带铺展在烘烤底板上或者将其
铺展已被烘烤透的生面层之上。然后对其进行下一
道烘烤。为了提高生产率和稳定产品质量，将未经烘
烤的生面带(9.1-9.4)连续地送入相间设置并能进行
控温(A-D，O，U)的顺序排列的烘烤段(1.1-1.4)。
依此，将生面带烤透，制成多层糕点(10)。
Patent CN-1125059-A (CN)
Inventor: BAOLI WANG
IPC: A23K10/22
Filed: 1995-07-21
Abstract: 红壤地区高产蛋鸭饲料，公开了两个饲料配方以及能量添加剂，复合矿物饲料的配方：其一为稻谷占36.0％组，其二为玉米占36.0％组，其余组分为菜粕、豆粕、鱼粉、三等面粉、食盐、能量添加剂、复合矿物等按给出百分比配料加工而成。本发明能使蛋鸭产蛋率达到85％以上，并能有效预防高产蛋鸭的拐腿、产后瘫痪、闭蛋突然死亡和产薄壳蛋、软壳蛋等病症。是红壤地区高产蛋鸭的专用饲料。
Patent CN-1143945-A (CN)
Inventor: MAHLER B A
IPC: C07C19/08
Filed: 1995-03-13
Abstract: 本发明公开了利用包含醇类的萃取剂萃取蒸馏，使1，1，2，2-四氟乙烷(HFC-134)和1，1，1，2-四氟乙烷(HFC-134a)彼此分离和/或与氟碳化合物杂质分离的方法。合适的萃取剂实例包括至少一种选自如下的化合物：甲醇，丁醇，乙醇，丙醇，它们的异构体及环状化合物等等。
Patent CN-1222819-A (CN)
Title: 手提式通信设备
Inventor: DEGUCHI MANABU
IPC: H04B1/3822
Filed: 1998-11-17
Abstract: 手提式通信设备包括,箭头键,用于移动高亮把已选择在显示器上显示的多条信息之一和输入键用于执行所选择的信息条目。箭头键和输入键在机壳上的一个区域中彼此靠近地形成。
Patent CN-1284848-A (CN)
Title: 污斑掩蔽底片在吸湿用品中的应用
Inventor: CARLUCCI GIOVANNI
IPC: A61F13/514
Filed: 1998-12-09
Abstract: 本发明涉及吸湿用品如卫生巾和短裤衬里,以及其中含有三维成形薄膜的底片构造在吸湿用品中的应用,以便当通过吸湿用品的朝向衣物的表面观察时,含有三维成形薄膜的底片构造对吸湿用品中所储存的物质提供掩蔽作用。
Patent CN-1266533-A (CN)
Title: 生产导电合成物的工艺以及由此生产的导电合成物
Inventor: TAKETSUGU SASAKI
IPC: C09D5/24
Filed: 1999-07-14
Abstract: 本发明提供了一种用于生产适合于形成电子元件的电极的诸如导电膜料之类的导电合成物的工艺,其中导电粉末分解为一次粒子或近一次粒子,并满意地分散在合成物中。将导电粉末分解为一次粒子或近一次粒子,并通过如下方法中的至少一种,满意地分散:使含有导电粉末的浆料压缩,并在分流通道17和18内通过,并且在碰撞室19中使分流合并;使一个浆料流撞击碰撞壁;或使浆料迅速地通过窄的通道,从而使导电粉末受到切变应力。
Patent CR-20150529-A (CR)
Title: Catéter de balón con actuador hidráulico
Inventor: HAARMANN-THIEMANN ANNA MARIE
IPC: A61F2/966
Filed: 2015-10-09
Abstract: Catéter que incluye un miembro tubular interior, un miembro tubular exterior móvil con respecto al miembro tubular interior, y un miembro expansible acoplado a la porción del extremo distal del miembro tubular interior. El miembro expansible que tiene una cámara interior y transiciona entre una configuración desinflada y una configuración inflada.
Patent CR-20170208-A (CR)
Title: Agonistas parciales del receptor de insulina
Inventor: YAN LIN
IPC: C07K14/62
Filed: 2015-11-19
Abstract: Se divulgan dímeros de insulina y dímeros de análogo de insulina que actúan como agonistas parciales en el receptor de insulina.
Patent CR-20210598-A (CR)
Title: Hair cutter blade gap adjustment system
Inventor: COLPITTS DENNIS J
IPC: B26B19/20
Filed: 2020-04-21
Abstract: A hair cutting system includes a handle defining a longitudinal axis, a strut mounted to the handle and a hair cutting blade assembly coupled to the strut. The cutting blade assembly includes a stationary blade defining cutting teeth having blade edges and a movable blade defining cutting teeth having blade edges and capable of reciprocal movement relative to the stationary blade in a horizontal direction. The movable blade and the stationary blade are movable relative to each other in a longitudinal direction to adjust a longitudinal position of the movable blade relative to the stationary blade to selectively vary a distance between the blade edges of the stationary blade and the blade edges of the movable blade. A releasable lock is configured to selectively lock and release the stationary blade and the movable blade with respect to each other in the longitudinal direction.
Patent CR-20220128-A (CR)
Title: Dispersiones sólidas amorfas de fármaco-polímero usando polímeros de poli(ácido acrílico) lineales
Inventor: DRAGANOIU ELENA S
IPC: A61P31/10
Filed: 2020-08-28
Abstract: Una dispersión sólida amorfa incluye un poli(ácido acrílico) lineal y un ingrediente farmacéutico activo. El poli(ácido acrílico) lineal usado para formar la dispersión sólida amorfa tiene una viscosidad Brookfield de al menos 0.1 Pa·s (100 cP) a 25 °C. Un método para formar tal dispersión sólida amorfa de un ingrediente farmacéutico activo incluye formar una dispersión líquida de un poli(ácido acrílico) lineal, un ingrediente farmacéutico activo y un sistema disolvente, el poli(ácido acrílico) lineal con una viscosidad Brookfield a 25 °C de al menos 0.1 Pa·s (100 cP) y evaporar el sistema disolvente de la dispersión líquida para formar una dispersión sólida amorfa.
Patent EC-SP003497-A (EC)
Title: Sal mutua de amlodipino y atorvastatina
Inventor: HAMANAKA ERNEST SEIICHI
IPC: C07D401/12
Filed: 2000-05-25
Abstract: Esta invención se refiere a una sal mutua de amlodipino y atrovastatina, a composiciones farmacéuticas de dicha sal ya procediminetos de tratamiento de la angina de pecho, la eterosclerosis y la hipertensión e hiperlipidemia conjuntas, en los mamíferos, con tal sal mutua y con tales composiciones. Esta invención también se refiere a procedimientos de tratamiento del riesgo cardiaco en un mamifero que presenta sintomas de riesgo cardiaco, incluyendo los seres humanos, mediante la administración del tal sal mutua y de tales composiciones.
Patent EC-SP066902-A (EC)
Title: Soluciones sólidas supersaturadas estabilizadas de drogas esteroides
Inventor: LIPP RALPH
IPC: A61K47/44
Filed: 2006-10-02
Abstract: La presente invención se refiere a una composición farmacéu-tica con disolución de drogas lipofílicas mejoradas en un medio acuoso. Se comprobó que composiciones farmacéuticas que comprenden un polvo de compuestos lipofílicos tales como hormonas, y esteroides (por ejemplo, drospirenona y valerato de estradiol) en forma dispersa a nivel molecular junto a un vehículo que posee un área superficial específica de al me-nos 250 m2/g, tal como dióxido de silicio, por ejemplo, di-óxido de silicio comercializado bajo la denominación Aero-perl®, posee mejores propiedades de disolución de la droga lipofílica.
Patent EC-SP088377-A (EC)
Title: Derivados de carbamoilbenzotriazol como inhibidores de lipasas y fosfolipasas
Inventor: PETRY STEFAN
IPC: C07D249/18
Filed: 2008-04-17
Abstract: La invención se refiere a derivados de benzotriazol de la fórmula general (I) con los significados indicados en la descripción, a sus sales de uso farmacéutico y a su uso como medicamentos. (I)
Patent EC-SP982529-A (EC)
Title: Derivados de la 9-oxima eritromicina
Inventor: WU YONG JIN
IPC: C07D309/14
Filed: 1998-06-11
Abstract: La invención se refiere a los compuestos de fórmula I (gráfico), y a las sales farmacéuticamente aceptables de los mismos, en la que R1, R2, R6 y X son lo definido en la presente. La invención también se refiere a composiciones farmacéuticas que contienen los compuestos de fórmula I, a procedimientos para la utilización de dichos compuestos de fórmula I en el tratamiento de las infecciones bacterianas y protozoarias y a procedimientos para la preparación de dichos compuestos de fórmula I.
Patent FI-20030933-A (FI)
Inventor: LIOTTA DENNIS C
IPC: C07H19/10
Filed: 2003-06-24
Abstract: The present invention relates to a method of preparing BCH-189 and various analogues of BCH-189 from inexpensive precursors with the option of introducing functionality as needed. This synthetic route allows the stereoselective preparation of the biologically active isomer of these compounds, ²-BCH-189 and related compounds. Furthermore, the stereochemistry at the nucleoside 4'-position can be controlled to produce enantiomerically-enriched ²-BCH-189 and its analogues.
Patent GB-1050740-A (GB)
IPC: C07D209/12
Abstract: 1,050,740. Indole derivatives. MERCK & CO. Inc. Jan. 29, 1964 [Feb. 1, 1963], No. 2071/66. Divided out of 1,050.728. Heading C2C. Compounds of the Formula I, wherein R 1  is an aryl, heteroaryl or substituted aryl or heteroaryl group, R 2  is a hydrogen atom or a C 1-5  alkyl, C 2-5  alkenyl, aryl, aralkyl, alkaryl or substituted alkyl or aryl radical, R 3  is hydrogen or a C 1-5  alkyl or C 2-5  alkenyl radical and R 5  is a hydrogen or halogen atom or a C 1-5  alkyl, C 1-5  alkoxy, haloalkyl, nitro, amino, substituted amino, cyano, aminomethyl, alkyl-substituted aminomethyl, mercapto, dialkylsulphamoyl or benzylmercapto radical and R x  is an alkyl, aralkyl, alkonyl or cycloalkyl radical, are prepared by heating a compound of the Formula II with a compound of the formula R x OH in the presence of an acid catalyst and N-acylating the product with an acylating agent derived from an acid of the formula R 1 COOH. Alternatively the starting material II may be refluxed with acid in a non-alcoholic medium to give the free acid of I, which is then esterified with an alcohol R x OH and acid and N-acylated with an acylating agent derived from R 1 COOH. The exemplified product is methyl α-(1-pchlorobenzoyl - 2 - methyl - 5 - methoxy - 3 - indolyl)-acetate. Indolenins of Formula II are made by adding a dilute acid solution of a p-R 5 -benzenediazonium salt to an alcoholic caustic soda solution of a compound of the formula wherein R z  is an alkyl radical, refluxing the resulting hydrazone with alcoholic ZnCl 2  to form the di-ester of a 2-carboxy-indolenin-3-acetic acid, hydrolysing to give the free acid and heating on a steam bath to remove the 2-carboxy group.