baber/WOPTO huggingface dataset:
Patent CA-2764029-A1 (CA)
Inventor: REUTELINGSPERGER CHRISTIAAN PETER MARIA
IPC: C07K14/435
Filed: 2010-06-03
Abstract: An Annexin A5 variant, comprising one or more RGD (Arg-Gly-Asp) sequences, is suitable for use in the treatment of a disease in mammals, including humans, wherein augmentation of phagocytosis is a desired effect of treatment. The Annexin A5 variant can e.g. be used in the treatment of chronic inflammatory diseases such as atherosclerotic plaque or in the treatment of COPD. At least one RGD sequence may substitute sequences of three amino acids within the range 1-19or other regions of the amino acid sequences of Annexin A5; alternatively one or more RGD sequences may be part of an extension at the N-terminal side.
Patent CA-2764507-A1 (CA)
Title: Voltage source converter
Inventor: CROOKES WILLIAM
IPC: H02M7/483
Filed: 2009-06-22
Abstract: A voltage source converter (37) for use in high voltage DC power transmission and reactive power compensation.  The voltage source converter (37) comprises at least one converter limb (34) including first and second DC terminals (36, 38) for connection in use to a DC network (22) and an AC terminal (44) for connection in use to an AC network (20). The or each converter limb (34) defines first and second limb portions (34a, 34b), each limb portion (34a, 34b) including at least one switching element (40) connected in series with a chain-link converter (42) between a respective one of the first and second DC terminals (36, 38) and the AC terminal (44). The switching elements (40) of the first and second limb portions (34q, 34b) is operable to switch the respective chain-link converters (42) in and out of circuit between the respective DC terminal (36, 38) and the AC terminal (44). The chain-link converters (42) are operable to generate a voltage waveform at the AC terminal (44).
Patent CA-2764675-A1 (CA)
Inventor: LIN JOSEPH
IPC: A63C5/00
Filed: 2012-01-17
Abstract: A snow sled is provided for use on snow. The sled has a seating portion having a lower portion that is configured to slide on snow, and an upper portion that has a membrane for supporting a person, the seating portion including a frame that defines the upper and lower portions. The sled also includes a steering portion formed separately from the seating portion and having a ski support, a single front ski, and an arm having opposing ends that are pivotably coupled to the ski support and the front ski. The sled further includes a steering mechanism pivotably coupling the seating portion and the ski support of the steering portion. The pivotable couplings between the arm and the ski support and the front ski, together with the pivotable couplings between the steering mechanism and the seating portion and the ski support, are configured to allow for the front ski to be folded and stored under the seating portion. A braking member can also be provided at each end of the opposing ends of the ski support.
Patent CA-2765795-A1 (CA)
Title: Multicomponent cartridge with venting apparatus
Inventor: JUTZI PAUL
IPC: B65D81/32
Filed: 2010-05-31
Abstract: The invention relates to a multi-component cartridge (1) comprising a first reservoir (6) for a first component (8), and a second reservoir (7) for a second component (9), wherein the first reservoir (6) is separate from the second reservoir (7). The first reservoir (6) is arranged adjacent to the second reservoir (7). In the first reservoir (6), a first piston (3) is movably accommodated, and in the second reservoir (7), a second piston (4) is movably accommodated. Each of the first or second reservoirs is provided with a filling end (12, 13) and a discharge end (14, 15). The first and second reservoirs (6, 7) are connected to each other at least at the discharge end (14, 15). The first and second reservoirs (6, 7) have a first and second longitudinal dimension (16, 17) extending between the respective filling end (12, 13) and the corresponding discharge end (14, 15). The first reservoir (6) has a first inside wall (24), and the second reservoir (7) has a second inside wall (25), wherein the discharge end (14, 15) opens into a discharge element (18, 19) in a mouth. Upstream from the mouth (20, 21), a ventilation element (22, 23) is arranged on at least one of the inside walls (24, 25) of at least one of the first or second reservoirs (6, 7), wherein the ventilation element (22, 23) extends over maximally one third of the longitudinal dimension (16, 17) of the reservoir (6, 7).
Patent CA-2767135-A1 (CA)
Title: Application of conformal sub boundary layer vortex generators to a foil of aero/hydrodynamic surface
Inventor: IRELAND PETER S
IPC: F15D1/12
Filed: 2010-07-09
Abstract: A method of improving aerodynamic performance of foils by the application of conformal, low drag vortex generators. A film of erosion protection material or other conformal material is placed on the foil to provide a medium for the incorporation of planform edge vortex generators. The form edge is shaped to achieve submerged vortex generating shapes of chevron or ogival planforms, extending primarily chordwise on the foil surface. The vortex generators promote improved boundary layer dynamics by mixing free stream flow into the boundary layer while minimising separation and fluid losses. At the trailing edge, the shape formed with the chevrons applied apex forward, acts as a vented gurney tab series and additionally as disruptors to the Von Karman Street wake, delaying sheet rollup into the tip vortice.
Patent CA-2767376-A1 (CA)
Inventor: TERRANOVA ERIC
IPC: C07F9/655
Filed: 2005-05-13
Abstract: Optionally 7-substituted or 7,7-disubstituted 2-(formyl or substituted methyl)-(5H,9H)-6,8-dioxabenzocycloheptenes (I) are new. Dioxabenzocycloheptene derivatives of formula (I) and their optical isomers are new. A : -CH 2Y 1> or -CHO; Y 1>halo (specifically Cl or Br), OH, OSO 3R 2> or P(O)(OR 3>) 2; R, R 1>H (but preferably not both H), alkyl, alkoxy or aryl (optionally substituted by 1-5 of halo, alkyl, alkoxy, CN and/or NO 2); or R + R 1>group completing a 5-6C ring (specifically a cyclopentane or cyclohexane ring); R 2>alkyl or aryl; R 3>alkyl. Independent claims are included for: (A) the preparation of (I); (B) the synthesis of non-steroidal vitamin D analogs, specifically (3,4-bis-hydroxymethyl-phenyl)-methyl-substituted biphenyl derivatives of formula (IV), using (I) in at least one of the stages; and (C) the use of biphenyl derivatives of formula (II) for the preparation of (IV). X : CH 2, NH, NR 8> or O; R 4>, R 5>, R 8>1-3C alkyl; R 6>, R 7>Me, Et, CF 3 or C 2F 5; Z 1>OH, NHR 8>, NH 2 or CHO. [Image] [Image] ACTIVITY : None given. MECHANISM OF ACTION : None given.
Patent CA-2768333-A1 (CA)
Title: 1h-quinazoline-2, 4 -diones for use in the treatment of neuronal ceroid lipofuscinosis
Inventor: KALKMAN HANS O
IPC: A61P25/28
Filed: 2010-07-23
Abstract: The invention concerns the use of competitive AMPA receptor antagonists for the treatment, prevention or delay of progression of neuronal ceroid lipofuscinosis.
Patent CA-2769746-A1 (CA)
Inventor: KILAMBI SRINIVAS
IPC: C13K1/02
Filed: 2011-01-19
Abstract: Methods are disclosed for the continuous treatment of biomass comprising a pretreatment step, wherein said biomass is contacted with a first supercritical, near-critical, or sub-critical fluid to form a solid matrix and a first liquid fraction; and a hydrolysis step, wherein said solid matrix formed in said pretreatment step is contacted with a second supercritical or near-supercritical fluid to produce a second liquid fraction and a insoluble lignin-containing fraction. Also disclosed are apparatuses for the continuous conversion of biomass comprising a pretreatment reactor and a hydrolysis reactor associated with said pretreatment reactor.
Patent CA-2769996-A1 (CA)
Title: Plasmodium falciparum sporozoite and liver stage antigens
Inventor: LIMBACH KEITH
IPC: A61K39/00
Filed: 2010-11-03
Abstract: The invention provides novel malaria polypeptides expressed at the preerythrocytic stage of the malaria life-cycle. The antigens can be utilized to induce an immune response against malaria in a mammal by administering the antigens in vaccine formulations or expressing the antigens in DNA or other nucleic acid expression systems delivered as a vaccine formulation.
Patent CA-2772011-A1 (CA)
Title: A freight carrier
Inventor: BENNETTO PETER G
IPC: B60P3/42
Filed: 2010-09-01
Abstract: A freight carrier (10) in the form of a flatbed road trailer of the side loading type, has a load deck (16) and includes two bulk container tanks (20.1) and (20.2) for carrying liquid freight. The carrier includes lifting arrangements at opposite ends of the tanks for lifting the tanks into the raised positions illustrated, so as to define stowage compartments under the tanks within which general dry freight can be supported on the load deck. The trailer transports liquid freight when the tanks are in their lowered positions adjacent the load deck. When the tanks are empty, they are raised for the transport of dry freight.
Patent CA-2773135-A1 (CA)
Title: Parking meter communications for remote payment with updated display
Inventor: KING DAVID WILLIAM
IPC: G06Q20/00
Filed: 2010-09-03
Abstract: A parking meter receives data indicative of a remote payment being completed and displays an amount of time purchased by the remote payment for a parking session. The parking meter determines an amount of time remaining in the parking session and powers down at least a portion of a meter communication subsystem subsequent to receiving the data indicative of the remote payment being completed. The parking meter wakes up the powered down portion of the communication subsystem upon determining that the amount of time remaining is below a threshold time, and can receive an indication of additional time being paid for remotely, and can update the displayed time remaining to reflect the additional time.
Patent CA-2773286-A1 (CA)
Title: Disulfide stabilised multivalent antibodies
Inventor: ADAMS RALPH
IPC: C07K16/28
Filed: 2010-09-24
Abstract: A multivalent antibody fusion protein which comprises an immunoglobulin moiety, for example a Fab or Fab' fragment, with a first specificity for an antigen of interest, and further comprises two single domain antibodies (dAb) with specificity for a second antigen of interest which are a VH/VL pair, wherein the two single domain antibodies are linked by a disulfide bond.  Also provided are particular dual specificity antibody fusion proteins and other antibody fragments which are stabilised by a disulfide bond.
Patent CA-2773671-A1 (CA)
Title: Variable angle compression plate
Inventor: KOAY KENNY
IPC: A61B17/80
Filed: 2010-09-14
Abstract: A bone plate, (100) comprises a first surface (102) and a second surface (104) in combination with a first hole (106) extending through the bone plate from the first surface to the second surface, the hole including a compression portion (112) and a variable angle portion (114) open to one another by a connecting space (134), the compression portion including a sloping surface adapted to engage a head of a bone fixation element inserted thereinto so that the bone fixation element imparts a force to the bone plate to move the bone plate laterally relative to a portion of bone into which the bone fixation element is inserted, the variable angle portion including a plurality of columns (120) positioned about a circumference of a wall of the variable angle portion, the columns being separated from one another by a plurality of gaps (122) positioned between adjacent pairs of columns and including a plurality of protrusions (132) extending radially inward therefrom.
Patent CA-2774398-A1 (CA)
Inventor: LANE RICHARD
IPC: G06Q40/04
Filed: 2010-10-19
Abstract: Certains modes de réalisation de l'invention réduisent les risques habituellement liés à la programmation des algorithmes, tels que les erreurs de syntaxe, le manque de clarté de la logique ou la nécessité de faire appel à un programmeur qui ne soit pas opérateur en bourse et qui suive les indications d'un opérateur en bourse pour développer l'algorithme exigé, car ces modes de réalisation limitent ou suppriment l'écriture d'un code de programmation par un utilisateur. Certains modes de réalisation mettent à disposition des boutons pour les blocs de structure ainsi qu'une zone d'algorithme prévue pour définir un algorithme. Certains modes de réalisation permettent une évaluation directe d'une expression au cours de la définition de l'algorithme. Certains modes de réalisation proposent une zone réservée à une trame d'élaboration ainsi que des blocs permettant d'élaborer un algorithme. Certains modes de réalisation assurent une rétroaction directe pour les blocs au fur et à mesure que l'algorithme est élaboré. Certains modes de réalisation permettent de passer un ordre devant être géré par un algorithme de bourse précis défini par l'utilisateur sur la base d'un axe de valeurs, et d'afficher les ordres en cours actuellement gérés par différents algorithmes de bourse définis par l'utilisateur sur ledit axe de valeurs. Certains modes de réalisation incluent un classement hiérarchique.
Patent CA-2775327-A1 (CA)
Title: Method, device and fluid for treatment of a heart after harvesting
Inventor: STEEN STIG
IPC: A61J1/00
Filed: 2010-09-22
Abstract: Method and device for treatment of a heart after harvesting and before transplantation. The device comprises a container (32) intended to comprise the heart (31); a first line (54) for connection to an aorta (30) of the heart; a fluid circuit comprising an oxygenator (37) for oxygenating said fluid and a heater/cooler (38) for regulating the temperature of said fluid; and a pump (36) for perfusion of said fluid through the coronary blood vessels of the heart. The fluid comprises an oncotic agent exerting an oncotic pressure larger than about 30 mmHg; and is cardioplegic by comprising a potassium concentration, which is between 15mM and 30 mM. A control device is arranged for controlling the pump to perform said perfusion intermittently, whereby the perfusion time is less than half of the cycle time. The perfusion is performed at a pressure, which is at least 15 mmHg and at least 15 mmHg lower than said oncotic pressure. The container (32) may be purged with fluid bypassing the heart between the perfusion steps. The perfusion cycle time may be 75 minutes and the perfusion time may be 15 minutes.
Patent CA-2775929-A1 (CA)
Inventor: TOUITOU ELKA
IPC: A01N25/00
Filed: 2010-10-01
Abstract: Provided are novel compositions exhibiting highly effective antiviral, antimicrobial and/or antifungal activity. The compositions of the invention can be used for sanitizing and/or disinfecting surfaces, e.g., inanimate and/or animate surfaces. Preferred compositions include a synergistic combination of an alcohol, docusate, geraniol and, optionally, menthol. The invention provides compositions that have high antimicrobial activity, yet are mild, non-irritating, quick drying, non- sticky and not drying to the skin. Processes for manufacturing and using the compositions and products containing such compositions are also disclosed.
Patent CA-2776321-A1 (CA)
Title: Spectrometer
Inventor: VILLENEUVE ALAIN
IPC: G01J3/10
Filed: 2010-09-30
Abstract: A spectrometer (110) including a triggering element (124) for generating a series of trigger signals, a first laser (10) for emitting toward a sample (112) a first laser light pulse (118) having a first wavelength in response to receiving each of the trigger signals, the first laser (10) being wavelength tunable so that the first wavelength is selectively variable; a second laser (114) for emitting toward the sample a second laser light pulse (120) having a second wavelength in response to receiving each of the trigger signals from the series of trigger signals; a dithering element (128) for selectively retarding transmission of the trigger signals to at least one of the first and second lasers such that the first and second laser light pulses (118, 120) are received at the sample substantially non-simultaneously; a delaying element (126) for retarding transmission of the trigger signals to at least one of the first and second lasers in a manner such that the first and second laser light pulses (118, 120) are received at the sample substantially simultaneously when the dithering element (128) is inactive state.
Patent CA-2778015-A1 (CA)
Inventor: EBETINO FRANK HALLOCK
IPC: A61K31/66
Filed: 2010-10-26
Abstract: Novel bisphosphonate cyclic acetal compounds are disclosed, as well as methods of preparing the compounds, pharmaceutical compositions including the compounds, and administration of the compounds in methods of treating bone metabolism disorders, such as abnormal calcium and phosphate metabolism.
Patent CA-2779187-A1 (CA)
Inventor: WOLF WAYNE A
IPC: F16S1/02
Filed: 2012-06-04
Abstract: A seal, system and method for sealing a connection between adjacent barrier members each having a channel along one edge and flange along an opposed edge sized to be received within a corresponding channel of an adjacent barrier member. The seal comprises an elongate core having an opening extending longitudinally therealong and a plurality of fins extending therefrom. The system includes the seal and a wiper sized to surround the flange. The method comprises locating the wiper about the flange and the seal within the channel, engaging the flange within the channel and moving the second barrier member in a downward direction with the wiper below the channel of the second barrier member so as to remove and prevent debris from entering the connection between the channel and the flange.
Patent CA-2779317-A1 (CA)
Title: Light diode with cooling body
Inventor: GRAUVOGEL ULRICH
IPC: H05K1/02
Filed: 2010-05-19
Abstract: The invention relates to a light diode with a lighting body and connecting wires for operating a light diode. According to the invention, the lighting body is connected with a separate cooling body associated to the light diode, wherein the light diode is maintained on the circuit board by means of a clamping mechanism.
Patent CA-2779712-A1 (CA)
Inventor: PERLMAN ANDREW
IPC: C01B3/34
Filed: 2010-12-16
Abstract: The present invention relates to an enhanced oil recovery process that is integrated with a synthesis gas generation process, such as gasification or reforming, and an air separation process for generating (i) an oxygen stream for use, for example, in the syngas process or a combustion process, and (ii) a nitrogen stream for EOR use.
Patent CA-2780496-A1 (CA)
Inventor: THOMAS CHRISTOPHER L
IPC: H04N5/232
Filed: 2010-10-27
Abstract: Methods and systems are provided to switch television channels during a commercial break and automatically notify the viewer when the commercial on the original channel is over so that the user may switch back to watch the original channel. This permits a viewer to avoid commercials during live television while maximizing the viewing of desired content on the original channel. A television channel selection device includes two independent tuners. In normal operation, a first tuner provides channel-selected signals to a television. When a viewer sees a commercial, the system begins a process employing a second independent tuner to internally monitor the first tuner signal until the termination of the commercial is detected. In the meantime, the first tuner provides channel-selected signals so that the viewer may view other channels. The viewer is notified of the end of the commercials by one of a variety of notification techniques.
Patent CA-2780708-A1 (CA)
Inventor: PICCI PIERO
IPC: C07K16/28
Filed: 2010-11-12
Abstract: The present invention relates to a single-chain variable fragment (scFv) able to recognize an epitope of the extracellular domain of CD99 human protein. The single-chain variable fragment is able to recognize and specifically and selectively bind said epitope expressed on Ewing sarcoma cells. The fragment can thus be used for the diagnosis and treatment of Ewing sarcoma.
Patent CA-2781371-A1 (CA)
Inventor: KONRATH JOHN G
IPC: G01N33/50
Filed: 2010-11-17
Abstract: The present disclosure relates to assays for detecting and/or quantifying the amount of human NT-pro B-type natriuretic peptide, human pro B-type natriuretic peptide and human B-type natriuretic peptide in a test sample.
Patent CA-2783456-A1 (CA)
Title: Safety net assembly for opening in a cargo trailer
Inventor: KNOX HOWARD T
IPC: B62D63/08
Filed: 2012-07-20
Abstract: A safety net assembly for selectively blocking and exposing an opening in a cargo container having a wall assembly bounding a storage space. A flexible net is selectively placed in: i) a first state wherein the net spans a substantial height and width of an access opening; and ii) a second state wherein the opening is further exposed. With the net in the first state, the net has a first length between spaced first and second locations that spans a width portion of the opening along a horizontal line at a first height.  The net is extensible to allow the first location on the net to be lowered while maintaining the second location on the net at the first height so that the line between the first and second locations is angled from horizontal and has a second length between the first and second locations that is greater than the first length.
Patent CA-2783791-A1 (CA)
Title: Athletic performance monitoring system utilizing heart rate information
Inventor: NIMS JASON
IPC: A63B24/00
Filed: 2010-12-09
Abstract: Athletic activity may be monitored using heart rate in addition to or instead of other types of metrics. Accordingly, multiple different activity types may be compared based on heart rate information. Additionally, the heart rate information may be visualized by displaying the heart rate data over time or relative to pace or distance. Additionally, the system may allow a user to analyze his or her heart rate performance by identifying one or more portions of the athletic activity in which a user exhibited a specified range of heart rates. Athletic activity sessions may further be tagged with various indicators including weather, terrain, difficulty and intensity. According to one or more aspects, data for different types of activity metrics may be polled and/or transmitted to a system at different rates or based on different schedules. Moreover, users may specify whether sensed data may be uploaded, recorded and/or visualized prior to or during an activity session.
Patent CA-2784434-A1 (CA)
Title: Assay for diagnosis of cardiac myocyte damage
Inventor: ADAMCZYK MACIEJ
IPC: G01N33/50
Filed: 2010-11-17
Abstract: Assays are disclosed for diagnosing a clinical condition, assessing risk or predicting an outcome as a result of cardiac myocyte damage. Immunoassay methods and kits provide for the assessment of cardiac myocyte damage by determining the presence of multiple cardiac myocyte antigens in a test sample, and combining the multiple determinations in a single assay result.
Patent CA-2785337-A1 (CA)
Inventor: FREDERICK WILLIAM
IPC: A01K97/10
Filed: 2012-08-15
Abstract: The ice fishing assembly includes a rod, a reel and a jigging arm which causes the line wound around the reel to jig. The inner end of the rod is accommodated in a socket which is biased upward by a contact of an electrical switch. When the weight of a fish at the end of the line exceeds the upward bias of the contact, the socket pivots downward and the switch closes with resulting activation of a buzzer or a signal light A built-in handle is provided for lifting the entire assembly so that it can be picket up with one hand and operated at a height most convenient for reeling in a fish with the other hand.
Patent CA-2785845-A1 (CA)
Inventor: HIPSKIND JOHN DANIEL
IPC: C12N15/82
Filed: 2010-12-13
Abstract: Control of transgene expression in planta is dependent upon genetic elements that affect both transcription and translation of mRNA transcripts. The disclosed invention describes the combination of DNA elements from four different plant viruses that function as an activator of transcription and enhancer of translation of mRNA transcripts in transgenic plants.