baber/WOPTO huggingface dataset:
Patent CA-3145331-A1 (CA)
Title: Polyoxometalate-based electrolyte conductor material and preparation method and application thereof
Inventor: ZHENG ZHAO
IPC: C08G65/48
Filed: 2019-10-18
Abstract: A polyacid-based electrolyte conductor material and a preparation method and application thereof, specifically including two preparation methods: a solid-state melting method and a solvent method. The prepared polyacid-based electrolyte conductor material forms a three-dimensional network by means of hydrogen-bond interaction between the polyacid and the polymer, thereby realizing effective proton transfer. When the mass ratio of the polyacid is 70%, the conductivity of the conductor material may reach 1.01 × 10 -2 S cm -1 (- 80°C). In terms of mechanical properties, the viscosity of a sample is 273 Pa. s, guaranteeing the safety thereof as an electrolyte. The shear thinning behavior enables the polyacid-based electrolyte conductor material to have good processability.
Patent CA-3146306-A1 (CA)
Title: Multikinase degraders
Inventor: STATSYUK ALEXANDER
IPC: C07D401/14
Filed: 2020-07-28
Abstract: Multikinase degraders described herein contain on one end a Von Hippel-Lindau (VHL) E3 ligase ligand or cereblon E3 ligase recruiter moiety, which bind to the VHL or cereblon E3 ubiquitin ligase (defined as a ubiquitin ligand binding moiety or ULM group), respectively, and on the other end a promiscuous kinase ligand that binds a target protein kinase (defined as a protein/polypeptide targeting moiety or PTM group), such that the target protein is in close proximity to the ubiquitin ligase. This leads to the ubiquitination and subsequent degradation (and inhibition) of the target protein. Specific present multikinase degraders as shown bind about 360 out of 400 tested kinases, showing that they are much more general kinase binders and degraders than any previously reported.
Patent CA-3149379-A1 (CA)
Inventor: REISNER YAIR
IPC: C12N15/86
Filed: 2020-08-06
Abstract: L'invention concerne des méthodes de génération d'une population isolée de la maladie du greffon contre l'hôte (GVHD) induisant des cellules comprenant un phénotype de lymphocyte T à mémoire centrale (Tcm), les cellules étant des cellules induisant une tolérance et/ou pourvues d'une activité anti-maladie, et pouvant se diriger vers les ganglions lymphatiques après transplantation. L'invention concerne également des cellules générées selon les méthodes, des compositions pharmaceutiques et des méthodes de traitement.
Patent CA-3151007-A1 (CA)
Title: Mast and substructure
Inventor: REDDY PADIRA
IPC: E04H12/34
Filed: 2017-06-06
Abstract: A drilling rig may include a right substructure, left substructure, and a drill floor.  The drill floor may be pivotably coupled to lower boxes of the left and right substructure by struts. The substructures may include hydraulic cylinders positioned to raise the drill floor and a mast coupled to the drill floor into a raised position.
Patent CA-3152137-A1 (CA)
Title: Engine assembly and method for controlling an engine
Inventor: CHAMPIGNY LUC
IPC: F02M35/10
Filed: 2020-08-31
Abstract: A method for controlling a two-stroke engine operatively connected to a turbocharger, the turbocharger being in fluid communication with the engine to provide a boost pressure thereto, the method including: comparing one of (i) an actual power output of the engine; and (ii) an exhaust temperature representative of an actual temperature of exhaust gas being discharged by the engine, with a corresponding threshold value thereof; in response to the one of the actual power output of the engine and the exhaust temperature being less than the corresponding threshold value: determining a corrective amount of boost pressure to add to the boost pressure of the turbocharger; and controlling the turbocharger to increase the boost pressure of the turbocharger by the corrective amount. Another method for controlling a two-stroke engine operatively connected to a turbocharger is also disclosed.
Patent CA-3152361-A1 (CA)
Inventor: CHRISTIE CAMERON DAVID
IPC: G01S13/87
Filed: 2020-03-19
Abstract: A system for an autonomous vehicle includes an array of sensors, a time sensitive network switch, and a data-power interface. The array of sensors is configured to capture one or more objects in an external environment of the autonomous vehicle and generate sensor data based on the captured one or more objects. The time sensitive network switch is configured to receive the sensor data. The data-power interface separately couples at least two of the sensors in the array to the time sensitive network switch. The data-power interface includes power conductors, a first data conductor, and a second data conductor. The power conductors provide the elevated voltage from time sensitive network switch to sensors in the array to power the sensors and the first data conductor and a second data conductor are configured to provide a high-speed vehicle communication link between time sensitive network switch and sensors.
Patent CA-3152973-A1 (CA)
Inventor: HWANG TAE-HO
IPC: A61K31/454
Filed: 2020-08-31
Abstract: La présente invention concerne une composition pharmaceutique pour la prévention ou le traitement du cancer, comprenant comme principes actifs un virus de la vaccine et un inhibiteur de granulopoïèse comme principes actifs. La composition pharmaceutique pour le traitement du cancer, comprenant un virus de la vaccine et un inhibiteur de granulopoïèse comme principes actifs, de la présente invention, présente un effet anticancéreux supérieur et une innocuité supérieure par rapport au cas d'administration uniquement du virus de la vaccine existant. Par conséquent, la composition pharmaceutique comprenant un virus de la vaccine et un inhibiteur de granulopoïèse comme principes actifs, de la présente invention, peut être utilisée efficacement dans le traitement du cancer.
Patent CA-3156763-A1 (CA)
Title: Water sport device, in particular a foilboard
Inventor: ROSEN HERMANN
IPC: B63B32/64
Filed: 2020-11-02
Abstract: The invention relates to a water sport device, in particular a foilboard, comprising a floating body (4), in particular in the form of a swimming board, and a foil device (6) which is secured to the floating body (4) by means of a retaining device (8), wherein the foil device (6) arranged on a link (110, 11) of the retaining device (8) has at least one, preferably at least two foils (16), and it can be transferred via the retaining device (8) from an idle and/or starting position into an operating position below the floating body (4), wherein, in the operating position and during a forward movement, due to an uplift force caused by the foil device (6), the floating body (4) can be transferred into a position in which is spaced apart from the surface of the water, wherein the retaining device (8) has a drive, which is preferably designed as an electromechanical or electro-pneumatic drive (12), via which the foil device can be transferred, in particular extended and retracted and/or folded, from an idle and/or starting position into the operating position and/or from the operating position into the idle and/or starting position.
Patent CA-3157342-A1 (CA)
Title: Packages configured for improved sealing
Inventor: FERRIS KEVIN
IPC: B65D75/52
Filed: 2020-10-27
Abstract: A package is provided that is formed from a packaging material, such as film, having increased adhesive in critical locations, such as adjacent folds in the end seal and other areas so that that the increased adhesive can at least partially fill voids adjacent such folds. The additional, localized sealant material is applied in a plurality of discrete locations in the end seal or other region adjacent where folds are formed and overlap with a sealant layer so as to provide additional sealant material for at least partially filling the voids without being present throughout the entirety, majority or large portions of the packaging material.
Patent CA-3157508-A1 (CA)
Title: Immunotherapie anticancereuse nano-activee
Inventor: MEI KUO-CHING
IPC: C07H1/00
Filed: 2020-10-14
Abstract: Dans certains modes de réalisation, l'invention concerne une technologie de type plateforme pour faciliter une immunothérapie anticancéreuse. Dans certains modes de réalisation, la présente invention concerne des nanovecteurs qui facilitent l'administration d'un inhibiteur IDO conjointement avec un inducteur de mort cellulaire (inducteur ICD). L'inhibiteur IDO peut être conjugué à un composant de bicouche lipidique de nanovésicule. Dans un autre mode de réalisation encore, des procédés et des compositions sont divulgués, où un agent induisant l'ICD (par exemple, doxirubicine, oxaliplatine, etc.) et un inhibiteur de la voie IDO (par exemple, promédicament inhibiteur IDO) sont intégrés dans un nanovecteur (par exemple, nanoparticule revêtue d'une bicouche lipidique [LB], qui permet une administration systémique au siège d'un cancer du pancréas orthotopique.
Patent CA-3160921-A1 (CA)
Inventor: HEIBEL MICHAEL D
IPC: G21C17/108
Filed: 2020-12-06
Abstract: Disclosed herein is a method (300) pertaining to a power distribution of a reactor core of a nuclear installation, the method being executed on a general purpose computer. The method (300) comprises: measuring current values from a plurality of vanadium neutron detector assemblies (10) which are disposed in the reactor core of the nuclear installation (302); determining a measured relative core power distribution based upon the measured current values (304); producing a measured core power distribution based upon the measured relative core power distribution (306); and verifying that the reactor is operating within the licensed core operating limits based at least in part upon the measured core power distribution (308). Also disclosed herein is a vanadium neutron detector (1-5) assembly (10).
Patent CA-3161918-A1 (CA)
Inventor: CHRISTINZIO ALEXANDER
IPC: E21B21/08
Filed: 2020-12-28
Abstract: A method of hydraulic fracturing includes providing a fracturing fluid to a pump (50). The pump (50) includes a pressure sensor (64) for measuring pressure at a fluid end (56). The method further include injecting the fracturing fluid from the pump (50) into a wellhead via the fluid end (56), obtaining a first pressure measurement at a discharge side of the fluid end (56) via the pressure sensor (64), obtaining a second pressure measurement at the discharge side of the fluid end (56) via the pressure sensor (64), determining a pressure differential between the first pressure measurement and the second pressure measurement, and determining an operational condition of the fluid end (56) based at least in part on the pressure differential and a known or estimated correlation between the pressure differential and the operational condition.
Patent CA-3162672-A1 (CA)
Title: Procedes de regulation de formaldehyde
Inventor: FREEL BARRY A
IPC: C10K1/04
Filed: 2020-12-22
Abstract: Le formaldéhyde, un agent cancérigène connu, est un sous-produit indésirable de la pyrolyse classique de la biomasse. Il est décrit des méthodes utilisées pour réduire la teneur en formaldéhyde des produits liquides issus de la conversion thermique de la biomasse. En particulier, des méthodes sont fournies pour utiliser des liquides de trempe exempts d'eau afin d'obtenir des produits liquides pyrolytiques ayant une teneur réduite en formaldéhyde. Les produits découlant de ces méthodes comprennent des liquides dont la teneur en hydroxyacétaldéhyde est améliorée.
Patent CA-3167669-A1 (CA)
Title: Hydrophobic interaction chromatography for viral clearance
Inventor: RUPPINO JOHN
IPC: C07K16/24
Filed: 2021-01-15
Abstract: The present application provides a method for characterizing and/or determining viral clearance capacity of hydrophobic interaction chromatography (HIC) including experimental design for multivariate analysis of viral clearance of HIC. The method provides understanding of the mechanism of the viral clearance using HIC by running a D-Optimal design of experiment including evaluations of multiple factors, such as pH, buffer concentration, column loading concentration, flow rate of column, or hydrophobic strength of the HIC column.
Patent CA-3172334-A1 (CA)
Title: Strap channel having imbricate flaps
Inventor: SCHULZ FRIEDHELM
IPC: B65B13/06
Filed: 2021-02-25
Abstract: A strapping device for strapping packages, having a packing table via which the package is moved along a movement path through the device, having a strapping frame which is oriented transversely with respect to the movement path and through which the package passes during its movement through the device, having a strap channel which is open in the direction of the frame interior, is formed by the strapping frame and has at least two vertical channel legs which are arranged on both sides of the movement path of the package, and having a multiplicity of strap channel flaps which are secured on the strapping means channel so as to be moveable by way of an articulated leg and are provided with a covering leg which overlies approximately half of the channel opening in the direction of a strap channel longitudinal axis.
Patent CA-3173730-A1 (CA)
Inventor: VILINSKY GARY
IPC: A01K13/00
Filed: 2022-09-09
Abstract: A manual toothbrush that includes a handle, a first brush head, and a second brush head. The handle has a first end, a second end opposite to the first end, a grip disposed between the first and second ends of the handle, and a longitudinal axis extending through the grip, wherein each of the first and second ends is offset to the longitudinal axis. The first brush head is provided at the first end of the handle, the first brush head has a first set of bristles, the first brush head is disposed at a first angle measured relative to the longitudinal axis of the handle. The second brush head is provided at the second end of the handle, the second brush head has a second set of bristles, the second brush head is disposed at a second angle measured relative to the longitudinal axis of the handle.
Patent CA-3174945-A1 (CA)
Title: Dual chamber syringe assembly
Inventor: RYAN KEVIN M
IPC: A61M5/31
Filed: 2021-04-14
Abstract: A syringe having two variable volumes are described herein. The syringe includes a first stopper and a second stopper, the first stopper being connected to a plunger. A first variable volume is disposed between the first stopper and the second stopper and a second variable volume is between the second stopper and a distal end of a barrel of the syringe. A flow path structure is disposed at the distal end of the barrel, the flow path structure extending from the distal end of the barrel along the inner sidewall of the barrel.
Patent CA-3175319-A1 (CA)
Title: Method for the continuous synthesis of paracetamol
Inventor: LECOMTE-NORRANT EDITH
IPC: C07C233/25
Filed: 2021-04-27
Abstract: The present invention relates to a method for preparing paracetamol continuously, comprising a nitration step or a nitrosation step so as to obtain p-nitrophenol or p-nitrosophenol, respectively. The p-nitrophenol or p-nitrosophenol can then be converted to paracetamol by hydrogenation, followed by acylation. The method according to the present invention makes it possible to obtain paracetamol with very good regioselectivity and excellent yields.
Patent CA-3176091-A1 (CA)
Inventor: HEIN JASON ELLIS
IPC: C07D209/12
Filed: 2021-12-17
Abstract: A method of synthesizing indole compounds. The method may include allyllating an indole compound, oxidizing the resulting a-indolepropene, and reductively aminating the resulting indoleacetaldehyde, providing a tryptamine. The indole compound may be substituted with a functional group on the indole ring or may be unsubstituted indole. The method may include substitution, oxidation or other derivatization of the indole ring of the indole compound, of tryptophan, of the tryptamine, or of intermediates. The method may include oxidizing tryptophan or a ring-substituted tryptophan analogue and reductively aminating the resulting indoleacetaldehyde, providing a tryptamine. The method may be applied in a telescoped approach without isolation of intermediates. The method may be applied to production of indoles, a-indolepropenes, indole propyl diols, indoleacetaldehydes and tryptamines. Compounds from each of these classes of compounds are also provided herein.
Patent CA-3176375-A1 (CA)
Inventor: BROWN MILTON L
IPC: A61K38/54
Filed: 2021-04-21
Abstract: Une méthode de traitement d'une infection virale peut comprendre l'administration d'une composition pharmaceutique comprenant un modulateur du système rénine-angiotensine (RAS) à un sujet en ayant besoin pour atténuer les conséquences cellulaires et organiques de l'infection virale. L'atténuation peut comprendre l'inhibition d'espèces réactives de l'oxygène, l'inhibition de la libération de cytokines, la régulation à la hausse de l'enzyme de conversion de l'angiotensine 2 (ACE2) et/ou la régulation à la baisse du récepteur de type 1 de l'angiotensine II (ATI). Le modulateur du système rénine-angiotensine peut comprendre diverses combinaisons d'un inhibiteur des récepteurs de l'angiotensine (ARB), d'une angiotensine (1-7), d'un inhibiteur de la HMG-CoA réductase, d'un inhibiteur de l'enzyme de conversion de l'angiotensine (ACE), de 3,3'-diindolylméthane (DIM), d'indole-3-carbinol (I3C) et/ou de pirfénidone (PFD). De plus, au moins un composé parmi l'inhibiteur des récepteurs de l'angiotensine, l'angiotensine (1-7), l'inhibiteur de la HMG-CoA réductase, l'inhibiteur de l'enzyme de conversion de l'angiotensine, le 3,3'-diindolylméthane, l'indole-3-carbinol ou la pirfénidone peut être lié à un antioxydant.
Patent CA-3176937-A1 (CA)
Title: Methode et medicament pour favoriser la degradation d'une proteine mal repliee et d'un agregat de celle-ci
Inventor: LI JINAN
IPC: A61K38/43
Filed: 2021-03-24
Abstract: La présente invention porte sur une méthode pour favoriser la dégradation d'une protéine mal repliée et d'un aggrégat de celle-ci. La méthode comprend l'administration d'une quantité thérapeutiquement efficace de composants de la voie d'activation du plasminogène à un sujet. La présente invention concerne en outre un médicament contenant les composants de la voie d'activation du plasminogène, une composition pharmaceutique, un produit et un kit, qui sont utilisés pour prévenir et traiter des maladies provoquées par la protéine mal repliée et/ou son agrégat.
Patent CA-3177723-A1 (CA)
Title: Apparatus and method for forming a cigarette
Inventor: DEIHIMI SAMAN
IPC: A24C5/40
Filed: 2022-05-13
Abstract: There is provided an apparatus for forming a cigarette, in particular, consumer, home appliance machinery to automate a manual, laboured production of cannabis rod, commonly referred to as joints. The apparatus as herein described may provide an all-in-one solution for cannabis or smokable herbs storage, crushing, packing and rolling of custom sized joints, on command while minimizing maintenance and refill of consumables. In addition, the apparatus has the versatility to use a refillable cartridge as well as a single-use, nitrogen flushed and/or vacuum sealed cartridge, which may extend both shelf-life and the freshness of cannabis flower.
Patent CA-3179385-A1 (CA)
Title: Procede et composition pour ameliorer la qualite et les benefices du sommeil
Inventor: NELSON DEANNA J
IPC: A61K33/06
Filed: 2021-04-05
Abstract: L'invention concerne des composés, des compositions et des procédés de fabrication et d'utilisation pour améliorer la qualité et les bénéfices du sommeil et/ou de l'état de veille chez un sujet en ayant besoin.
Patent CA-3179526-A1 (CA)
Title: Macrocyclic diamine derivatives as ent inhibitors for the treatment of cancers, and combination thereof with adenosine receptor antagonists
Inventor: DELIGNY MICHAEL
IPC: C07D491/08
Filed: 2021-04-07
Abstract: The present invention relates to macrocyclic diamine derivatives of formula II, including pharmaceutically acceptable salts and solvates thereof. Compounds of the invention are inhibitors of ENT family transporter, especially of ENT1, and are useful as therapeutic compounds for the treatment of cancers. The invention also relates to the combined use of the macrocyclic diamine derivatives with an adenosine receptor antagonist, for the treatment of cancers.
Patent CA-3179730-A1 (CA)
Inventor: LAVIOLETTE STEVEN ROBERT
IPC: C07C39/23
Filed: 2021-04-09
Abstract: La formulation comprend un CBD et un agoniste PPAR. L'agoniste PPAR peut être un agoniste PPAR à base d'oméga-3 et plus particulièrement peut comprendre des parties DHA et EPA sensiblement égales.
Patent CA-3180070-A1 (CA)
Inventor: OUNI TUOMAS
IPC: C10G1/10
Filed: 2021-05-25
Abstract: The present invention relates to a process for purifying a pyrolyzed plastic waste, the process comprising the steps of providing the pyrolyzed plastic waste, wherein the pyrolyzed plastic waste is a liquid or a wax at 20 °C and 1 atm, contacting the pyrolyzed plastic waste with activated carbon yielding a pretreated 5 plastic waste and hydrogenating the pretreated plastic waste using hydrogen and a metal-based catalyst yielding a hydrogenated plastic waste suitable for steam cracking.
Patent CA-3182332-A1 (CA)
Title: Curable adhesive composition for multi-purpose bonding applications
Inventor: LUETZEN HENDRIK
IPC: C09J171/02
Filed: 2021-04-19
Abstract: The present invention relates to a curable adhesive composition based on acetoacetate compound, and to its use in multi-purpose bonding applications. In particular, the present invention relates to a curable adhesive composition based on a multifunctional acetoacetate compound and polyoxyalkylene polyamines.
Patent CA-3182556-A1 (CA)
Title: Mechanical property measuring apparatus, mechanical property measuring method, substance manufacturing equipment, substance management method, and substance manufacturing method
Inventor: OZEKI TAKAFUMI
IPC: G01N27/80
Filed: 2021-06-14
Abstract: Provided are a mechanical property measuring apparatus and method that can accurately measure a mechanical property through physical quantities, etc.  A mechanical property measuring apparatus (100) comprises: a physical quantity measuring unit (5) configured to measure a plurality of physical quantities of a measured object that includes a substance and a film on a surface of the substance; a calculation model generating unit (81) configured to select a plurality of pieces of learning data and generate a calculation model for calculating a mechanical property of the substance; and a mechanical property calculating unit (82) configured to calculate the mechanical property of the substance using the calculation model generated and at least two of the plurality of physical quantities, wherein the selection physical quantities include at least one physical quantity measured using a first measurement signal and at least one physical quantity measured using a second measurement signal.
Patent CA-3182583-A1 (CA)
Inventor: YUEN CORY A
IPC: A01C7/08
Filed: 2022-11-22
Abstract: An agricultural implement includes a frame including a center section and a first wing section and a second wing section flanking the center section. The first wing section and the second wing section are configured to move relative to the center section during transitions between a folded position and an unfolded position. The agricultural implement includes a first rigid tube assembly disposed on the center section having a first set of rigid tubes and a second set of rigid tubes, a second rigid tube assembly disposed on the first wing section, and a third rigid tube assembly disposed on the second wing section. The agricultural implement includes a structural support configured to enable movement of the first set of rigid tubes and the second set of rigid tubes relative to the center section and each other during the transitions between the folded position and the unfolded position.