baber/WOPTO huggingface dataset:
Patent NZ-542554-A (NZ)
Title: Use of carbamazepine derivatives for the treatment of agitation in dementia patients
Inventor: SHUA-HAIM JOSHUA
IPC: A61K31/55
Filed: 2004-03-31
Abstract: Disclosed is the use of a compound of formula (I) wherein (a) R1 and R2 together form an oxy group or (b) R1 is hydrogen and R2 is hydroxy or acetoxy, or a pharmaceutically acceptable salt thereof, for the manufacture of a pharmaceutical composition for the treatment of agitation, in particular behavioral agitation, especially in dementia patients; a method for the treatment of agitation; pharmaceutical compositions comprising a compound of formula (I); a combination comprising (a) a compound of formula (I) and (b) at least one compound selected from the group consisting of nootropic plant extracts, calcium antagonists, cholinesterase inhibitors, dihydroergotoxin, nicergoline, piracetame, purine derivates, pyritinol, vincamine and vinpocetine; and a commercial package including such combination.
Patent NZ-542745-A (NZ)
Title: Carbon dioxide insect trap with anti-dispersal top shield
Inventor: LEIGHTON FRANK
IPC: A01M1/06
Filed: 2004-03-19
Abstract: An insect trapping device includes a source of carbon dioxide such as a fuel burner (detail B) and an exhaust 28 through which the carbon dioxide is vented in an upward direction. A suction device 36 draws air and entrained insects into the apparatus, the insects being drawn through the region near where the carbon dioxide is exhausted. The insects drawn into the apparatus are retained and a top shield 38 is provided concentric with and above the exhaust to reduce dissipation of the exhausted carbon dioxide into the surrounding air.
Patent NZ-546388-A (NZ)
Title: Lamellar bodies for therapeutic purposes
Inventor: DOBBIE JAMES
IPC: A61K31/575
Filed: 2004-08-31
Abstract: Disclosed is a use of a composition comprising a therapeutically effective amount of lamellar bodies in the manufacture of a medicament for the treatment of a disease or a condition characterized by a preponderance of mucous secretions wherein said condition is selected from the group consisting of Otitis Media, cystic fibrosis, bronchitis, sinusitis, nasal congestion, asthma, bronchiectasis, chronic obstructive pulmonary disease, hepato-biliary disorders, pancreatic and reproductive tract disorders and mucositis.
Patent NZ-548156-A (NZ)
Title: Crystalline polymorph of a bisulfate salt of a thrombin receptor antagonist
Inventor: THIRUVENGADAM TIRUVETTIPURAM K
IPC: A61P43/00
Filed: 2005-01-07
Abstract: Disclosed is a crystalline polymorph of compound 2, of the pictured formula, with a powder x-ray diffraction pattern as disclosed in the specification. Also disclosed is a process for preparing the above polymorph, and the use of the polymorph to treat thrombosis, atherosclerosis, restenosis, hypertension, angina pectoris, arrhythmia, heart failure, myocardial infarction, glomerulonephritis, thrombotic stroke, thromboembolic stroke, peripheral vascular diseases, inflammatory disorders, cerebral ischemia or cancer.
Patent NZ-550340-A (NZ)
Title: Prevention of retinopathy by inhibition of the visual cycle using a retinoid
Inventor: LARSEN LARS MICHAEL
IPC: A61K31/05
Filed: 2005-03-16
Abstract: Disclosed is the use of a compound of formula (V), wherein R11 is as defined in the specification, and wherein the double bonds may be cis or trans as defined in the specification, for the treatment of preproliferative diabetic retinopathy and of macular edema.
Patent NZ-551457-A (NZ)
Title: Treatment or prevention of respiratory viral infections with immunomodulator compounds
Inventor: TUTHILL CYNTHIA W
IPC: A01N43/06
Filed: 2005-05-12
Abstract: Disclosed is a use of an immunomodulator compound of Formula (A), wherein, n is 1 or 2, R is hydrogen, acyl, alkyl or a peptide fragment, and X is an aromatic or heterocyclic amino acid or a derivative thereof in the manufacture of a medicament for treating a respiratory viral infection (such as an influenza virus infection) in a subject infected with a respiratory virus or for preventing a respiratory viral infection in a subject at risk of infection by coronavirus, orthomyxovirus-coronavirus hybrid or SARS virus, or in the manufacture of a medicament consisting essentially of the immunomodulator of Formula (A) for preventing respiratory viral infection in a subject at risk of infection by a respiratory virus.
Patent NZ-552390-A (NZ)
Title: Novel fenofibrate formulations and related methods of treatment
Inventor: GUZMAN HECTOR
IPC: A61K31/192
Filed: 2005-08-04
Abstract: Provided is a liquid formulation comprising fenofibrate dissolved in a vehicle comprising an omega-3 fatty acid ethyl ester and an alcohol, wherein: the formulation comprises (i) about 5 % to about 20 % by weight of fenofibrate; (ii) about 55 % to about 85 % by weight of an omega-3 fatty acid ethyl ester; (iii) about 5 % to about 20 % by weight of an alcohol; and (iv) about 5 % to about 25 % by weight of a surfactant. Also provided are methods of increasing the solubility of fenofibrate and use of the composition in the manufacture of medicaments for treating hyperlipidemia.
Patent NZ-553936-A (NZ)
Title: Ear tag element and methods for producing an ear element
Inventor: CAISLEY ROY
IPC: A01K11/00
Filed: 2005-08-18
Abstract: An ear tag element for tagging animals is disclosed. The element comprises a body (1) and a transponder (4) which is embedded in the body (1). The transponder (4) has a chip and an antenna which are connected to one another. The body of the element comprises a rigid part (2), a flexible part (3) and a boundary surface (6) between these two parts. At least the antenna of the transponder (4) lies in the boundary surface (6), in such a manner that on at least one side the antenna bears against the rigid part (2) and on at least one other side bears against the flexible part (3) of the body (1).
Patent NZ-556589-A (NZ)
Title: Thickened spreadable warming lubricant
Inventor: CHUAH BENG SIM
Filed: 2005-03-24
Abstract: Disclosed is a substantially anhydrous, thickened, spreadable, warming lubricant composition comprising a mixture of glycerin, polyhydric alcohol, a non-ionic surfactant, and a Carbomer thickener, the surfactant improving wetting and spreadability of the composition on skin and latex, and the thickener providing a creamy rich feel to the composition, such that the composition can be applied to skin or a condom and provide an optimal warming effect upon contact with ambient moisture during use and such that the composition can be added to a condom package and, over the course of a week, spread and coat nearly the entire internal and external surfaces of the condom.
Patent NZ-571708-A (NZ)
Title: Two-element system to provide an ease of accomodation with variable-spherical aberration
Inventor: HONG XIN
IPC: A61F2/16
Filed: 2008-10-02
Abstract: An ophthalmic lens, comprising: an optic having two optical elements disposed in tandem along an optical axis, at least one of the elements being capable of lateral movement relative to the other along a direction substantially transverse to the optical axis, and at least two haptics (20, 22) each coupled to the optical elements by flexible hinges (26). The haptics have a cross-section in a plane formed by the optical axis and a lateral axis, the cross-section being a diagonal parallelogram having a major diagonal axis between two comers and a minor diagonal axis between two other comers, the minor diagonal axis being shorter than the major diagonal axis. The flexible hinges are at the ends of the major diagonal axis. The elements are configured such that the lateral movement causes a variation in an optical power provided by the optic as well as a variation in a spherical aberration exhibited by the optic.
Patent NZ-572797-A (NZ)
Title: Antimicrobial therapy for bacterial infections
Inventor: NIZET VICTOR
IPC: A01N57/10
Filed: 2007-05-11
Abstract: Use of a compound of formula (I) or (II) in the preparation of a medicament for the prevention or treatment of a microbial infection is disclosed, wherein the microbe expresses a carotenoid and wherein the compound inhibits the production of the carotenoid rendering the microbe more susceptible to oxidative damage, and wherein the substituents shown in formulae (I) and (II) are as defined in the specification. The disclosure also demonstrates that carotenoids serve as virulence/resistance factors in microbes. Examples demonstrate that (1) S. aureus carotenoid is a virulence factor that impairs neutrophil killing and promotes disease pathogenesis by virtue of its antioxidant properties, (2) evidence that pharmacological inhibition of the carotenoid pigment production renders the organism more susceptible to oxidants and blood killing; and (3) evidence that squalene synthesis inhibitors can block Staphylococcus aureus pigment production, and that squalene synthesis inhibition can reduce Staphylococcus aureus pathogenicity in vivo.
Patent NZ-576893-A (NZ)
Title: Tetralin analogs having sphingosine 1-phosphate agonist activity
Inventor: LYNCH KEVIN R
IPC: A61K31/381
Filed: 2007-11-21
Abstract: Discloses a 6-octyl-2-tetralone compound or pharmaceutically acceptable salts or ester with the general structure of formula (I). Further discloses the use of the compound for the manufacture of a medicament for treating pathological conditions where the activity of sphingosine 1-phosphate receptors is implicated and agonism of activity is desired. Further discloses the use of the compound for the manufacture of a medicament for treating pathological conditions where the sphingosine 1-phosphate lyase enzyme is implicated and inhibition of the lyase is desired. The disclosed 6-octyl-2-tetralone compound is a sphingosine analog.
Patent NZ-578283-A (NZ)
Title: Proteomic profiling method useful for condition diagnosis and monitoring, composition screening, and therapeutic monitoring
Inventor: CHAIRES JONATHAN B
IPC: A61B5/00
Filed: 2008-01-11
Abstract: Provided is a method of diagnosing or monitoring a condition of interest in a subject, comprising: generating a signature thermogram containing a protein composition pattern for a body fluid sample obtained from the subject; and comparing the signature thermogram to one or more standard thermograms selected from: a negative standard thermogram containing a protein composition pattern associated with an absence of the condition of interest; and a positive standard thermogram containing a protein composition pattern associated with a presence of the condition of interest; and identifying the subject as having the condition of interest or lacking the condition of interest, wherein comparing the signature thermogram to the one or more standard thermograms comprises: characterizing the signature thermogram as being: (a) within defined boundaries determined from a statistical and/or probability distribution function of the one or more standard thermograms; or (b) outside the defined boundaries determined from the statistical and/or probability distribution function of the one or more standard thermograms; and further comprising: identifying the subject as having the condition of interest when the signature thermogram is within the defined boundaries of the positive standard thermogram or identifying the subject as lacking the condition of interest when the signature thermogram is outside the defined boundaries of the positive standard thermogram. The sample can be blood plasma sample and the disease can be cancer.
Patent NZ-580487-A (NZ)
Title: Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells
Inventor: BRAHMBHATT HIMANSHU
IPC: C12N15/11
Filed: 2008-03-26
Abstract: Disclosed is a composition comprising (a) a plurality of intact, bacterially-derived minicells, wherein each minicell of said plurality encompasses regulatory RNA that is packaged in said minicell, and (b) a pharmaceutically acceptable carrier therefor, wherein there is an absence from said minicells of a construct for in situ expression of said regulatory RNA, wherein said regulatory RNA is selected from the group consisting of siRNA, miRNA and shRNA, and wherein said plurality contains a therapeutically effective amount of said regulatory RNA. Also disclosed is the use of the said composition in the preparation of a medicament for the treatment of cancer.
Patent NZ-580869-A (NZ)
Title: Methods for treating cancer
Inventor: LAUGHLIN MARK
IPC: A61K31/517
Filed: 2008-04-10
Abstract: Disclosed is the use of a compound in the manufacture of a medicament for treating cancer in a mammal at a particular dosage and in combination with an antiangiogenic agent, comprising the compound (4-Methoxy-phenyl)-methyl-(2-methyl-quinazolin-4-yl)amine hydrochloride, or a pharmaceutically acceptable salt or solvate thereof, wherein said particular dosage is not more than about 4.5 mg/m2. Also disclosed is the use of bevacizumab as the antioangiogenic agent.
Patent NZ-588488-A (NZ)
Title: Method for producing an intermediate product of dabigatran etexilate
Inventor: KOCH GUNTER
IPC: C07D401/12
Filed: 2009-06-12
Abstract: Disclosed is a process for synthesising the amidine benzimidazole derivative of formula 1, comprising reacting a diamine with an oxadiazolone, then without isolating the product, converting it to the amidine of formula 1, where the diamine and oxadiazolone have the structures given in the specification.
Patent NZ-590709-A (NZ)
Title: Process for the preparation of fertilizer and surfactant natural compositions for washing, reclamation and cultivation of contaminated soils and related compositions
Inventor: TERENZIO DOMENICO
IPC: C09K23/56
Filed: 2009-07-27
Abstract: Disclosed is a process for the preparation of a fertilizer composition comprising or consisting of the following steps: a) preparing a muddy mixture of fossil material in water; b) adding under agitation to the muddy mixture from step a) a solution of alginic acid and one or more alkaline agents together in solution or subsequently to each other and in proportion between said components and muddy mixture such that (i) the amount of alginic acid is from 0.50 per cent to 15 per cent, and (ii) the amount of alkaline agent is from 2 per cent to 17 per cent, said per cent being weight per cent with respect to total weight of the final mixture obtained from step b), and c) maintaining the mixture under stirring up to complete homogenization of whole kneading. Also disclosed is the use of the prepared fertilizer composition and the use of alginic acid for the preparation of fertilizer or surfactant compositions comprising humic extract and/or humic derivatives, from humified fossil materials.
Patent NZ-593622-A (NZ)
Title: Galenic formulations of organic compounds
Inventor: HIRSCH STEFAN
IPC: A61K9/00
Filed: 2010-01-27
Abstract: 593622 Disclosed is a solid unit dosage form for oral administration, wherein the unit dosage is in the form of a minitablet having a size of between 1 mm and 4 mm and having a core and an outer coating, wherein: the core comprises between about 2 mg and about 4 mg of aliskiren, or a pharmaceutically acceptable salt thereof; and the outer coating is in the form of a film-coat which comprises a taste masking material selected from polyacrylates, and/or a modified release coating component selected from cellulose derivatives and acrylic copolymers, and mixtures thereof, for use in the treatment of hypertension, congestive heart failure, angina, myocardial infarction, atherosclerosis, diabetic nephropathy, diabetic cardiac myopathy, renal insufficiency, peripheral vascular disease, left ventricular hypertrophy, cognitive dysfunction, stroke, headache and chronic heart failure.
Patent NZ-601080-A (NZ)
Title: Method for producing 3,4-disubstituted pyrrolidine derivative and production intermediate thereof
Inventor: ARAYA ICHIROU
IPC: C07D207/10
Filed: 2011-01-07
Abstract: 601080 The disclosure relates to a method for preparing (3R,4S)-3-(N-substituted aminomethyl)-4-fluoropyrrolidine or an enantiomer thereof which can be an intermediate for producing pharmaceuticals. It relates to a method for preparing (3R,4S)-3-(N-substituted cyciopropylaminomethyl)-4-fluoropyrrolidine derivative or ait’s enantiomer, or their salts, comprising a step of fluorinating a 4-hydroxy-3-(N-substituted aminomethyl)pyrrolidine derivative represented by the general formula (I) or an enantiomer thereof using a sulphur tetrafluoride derivative.
Patent NZ-602205-A (NZ)
Title: Drive assembly for a drug delivery device and drug delivery device
Inventor: LANGLEY CHRISTOPHER
IPC: A61M5/24
Filed: 2011-01-24
Abstract: 602205 Disclosed is a drive assembly for a drug delivery device. A drive assembly for a drug delivery device comprises a guide nut (4); a locking means (9); a body; a piston rod; a cartridge holder (2); a fastener (14) and a screw thread (8). The guide nut (4), which is a toothed wheel with interspaces, is rotatable around an axis of assembly and engages with the locking means (9). The locking means (9) is a mounted pawl or cantilever to inhibit rotation of the guide nut (4). The guide nut (4) and locking means (9) are arranged in the body. The locking means (9) is fastened to the body. The cartridge holder (2) is removable from the body. The fastener (14) is part of or fastened to the cartridge holder (2). The fastener (14) moves the locking means (9) radially with respect to the axis engaging the locking means (9) with the guide nut (4) when the cartridge holder (2) is attached to the body. The locking means (9) is held in a position so that the locking means (9) is engaged with the guide nut (4) for drug delivery. The screw thread (8) is couples the guide nut (4) and piston rod and enables a helical movement comprising a rotation and a simultaneous shift along the axis. The fastener (14) is a protruding part of the cartridge holder (2) and slides over the locking means (9) to engage the locking means (9) with the guide nut (4) by rotation of the cartridge holder (2).
Patent NZ-608582-A (NZ)
Title: Green wall planting support apparatus
Inventor: SUNG HSU-YANG
IPC: A01G9/02
Filed: 2013-03-25
Abstract: 608582 A green wall planting support apparatus includes at least one plant support structure and a plurality of baskets. The plant support structure includes a vertical main plate that has a plurality of basket hanging portions. A water supply unit includes at least one main pipe connected to a water source and a branch unit that is coupled to the main pipe and that has a plurality of watering conduits. Each of baskets has a basket body with a receiving space. The basket body has a basket hanger portion that is detachably connected to one of the basket hanging portions. The watering conduits convey water into the receiving spaces of the baskets I respectively.
Patent NZ-610977-A (NZ)
Title: Use of encapsulated oil in dough preparation
Inventor: ARFSTEN JUDITH
IPC: A23L9/20
Filed: 2011-12-23
Abstract: Disclosed is a process for the preparation of an oil cream comprising at least 60 % oil by weight, a maximum content of water of 40 %, and cross-linked protein, wherein the oil is encapsulated oil comprising an inner core of oil encapsulated in an outer shell of cross-linked protein, the process comprising the steps: a) preparing an emulsion by homogenization of oil in an aqueous protein solution; b) heating the emulsion at 70 to 90 °C for 5 to 15 minutes; c) concentrating the emulsion by microfiltration or centrifugation to reduce the water content of the oil cream to less than 35 % by weight.
Patent NZ-613762-A (NZ)
Title: Composite adsorbent material containing a porous carbon matrix
Inventor: DE LEIJ FRANCISCUS ANTONIUS ANNA MARIA
IPC: B01J20/28
Filed: 2012-02-02
Abstract: The disclosure relates to composite adsorbent material comprising a porous non-activated carbon carrier matrix and an adsorbent species comprising a reactive chemical, wherein the adsorbent species is disposed within pores of the carrier matrix and/or in the spaces between particles. The adsorbent species may be a metal or similar inorganic species. The disclosure also relates to the use of such composite adsorbent materials for water purification, metal recovery and removal of pollutants.
Patent NZ-613917-A (NZ)
Title: 9-[4-(3-chlor-2-fluor-phenylamino)-7-methoxy-quinazolin-6-yloxy]-1,4-diazaspiro[5.5]undecan-5-one dimaleate, use thereof as a drug, and production thereof
Inventor: OSTERMEIER MARKUS
IPC: C07D403/12
Filed: 2012-01-27
Abstract: Disclosed is crystalline 9-[4-(3-chloro-2-fluorophenylamino)-7-methoxy-quinazolin-6-yloxy]-1,4-diazaspiro[5.5]undecan-5-one dimaleate of formula (I) optionally in the form of the tautomers thereof, wherein reflections in the X-ray powder diagram occur at dhkl values of 7.11, 5.77, 4.69, 4.36, 4.15, 3.85 and 3.61 Å, and has corresponding values 2theta of 12.43, 15.33, 18.92, 20.37, 21.38, 23.06 and 24.67. Also disclosed is a process for the stereoselective preparation of the crystalline compound of formula (I) starting from 1,4-cyclohexanedione-mono-ethyleneketal. Also disclosed is a process for the chlorination of tert-butyl (trans)-9-(4-hydroxy-7-methoxy-quinazolin-6-yloxy)-5-oxo-1-(2,2,2-trifluoro-acetyl)-1,4-diaza-spiro[5.5]undecane-4-carboxylate or tert-butyl (trans)-9-(4-oxo-7-methoxy-quinazolin-6-yloxy)-5-oxo-1-(2,2,2-trifluoro-acetyl)-1,4-diaza-spiro[5.5]undecane-4-carboxylate with a reactant selected from among N-chlorosuccinimide/triphenylphosphane oxalyl chloride, thionyl chloride, phosphorus oxychloride, phosphorus pentachloride, carbon tetrachloride/triphenylphosphane, dichlorotriphenylphosphorane and P,P-dichlorophenylphosphine oxide, to form tert-butyl (trans)-9-(4-chloro-7-methoxy-quinazolin-6-yloxy)-5-oxo-1-(2,2,2-trifluoro-acetyl)-1,4-diaza-spiro[5.5]undecane-4-carboxylate. Further disclosed are intermediates such as tert-butyl (trans)-9-(3-benzyl-7-methoxy-4-oxo-3,4-dihydro-quinazolin-6-yloxy)-5-oxo-1-(2,2,2-trifluoro-acetyl)-1,4-diaza-spiro[5.5]undecane-4-carboxylate and (trans)-9-[4-(3-chloro-2-fluoro-phenylamino)-7-methoxy-quinazolin-6-yloxy]-1-(2,2,2-trifluoro-acetyl)-1,4-diaza-spiro[5.5]undecan-5-one hydrochloride.
Patent NZ-704179-A (NZ)
Title: Solid animal supplements and methods for making them
Inventor: FULLAGAR MARTIN
IPC: A23K50/15
Filed: 2013-06-07
Abstract: The present invention relates to solid animal supplement blocks that have high nutritional values and processes for their manufacture. The solid feed blocks comprise Condensed Molasses Solubles (CMS), a source of phosphorous and a liquid source. The solid feed blocks are suitable for use with rangeland animals.
Patent NZ-705601-A (NZ)
Title: Bioceramic compositions
Inventor: VISSMAN SHANNON
IPC: C08K3/00
Filed: 2013-09-19
Abstract: This invention relates to compositions and applications for a bioceramic composition that includes from about 45 to about 55 % by weight of kaolinite (Al2Si2O5(OH)4); from about 5 to about 15% by weight of tourmaline; from about 3 to about 13% by weight of aluminum oxide (Al2O3); from about 11 to about 19% by weight of silicon dioxide (S1O2); and from about 3 wt % to about 13 wt % zirconium oxide (ZrO2).
Patent NZ-708917-A (NZ)
Title: Information-bearing medium
Inventor: YAMAMURO HIROMI
IPC: C01B32/50
Filed: 2011-12-27
Abstract: A label or other information bearing medium equipped with a function for absorbing carbon dioxide is disclosed. When these are burned as waste at the end of their life they release CO2. An absorber helps to capture this CO2 and prevent it from entering the atmosphere. Provided are a label (101) to which a carbon dioxide absorbent (106) is added as part of the label or an adhesive layer (105). Also disclosed is a printing paper top layer formation material, an information-bearing medium, a solid fuel and a wristband clip. Further provided is a carbon dioxide reduction method for absorbing carbon dioxide by burning the same.