baber/WOPTO huggingface dataset:
Patent PT-1201749-E (PT)
Title: Method for producing cartilage implants using chondrocytes grown in-vitro
Inventor: JESCHKE BRIGITTE DR
IPC: A61K35/12
Filed: 2001-08-02
Abstract: The invention describes a process for the production of a human cartilage implant from chondrocytes cultured in vitro, which come as close as possible to the original with respect to their biochemical composition and biomechanical properties. Up to 20% by vol. of human serum are used as medium addition in the process. The chondrocytes can be kept in monolayer culture until the 12th passage in order firstly to be re-differentiated, incubated under a reduced oxygen partial pressure, and subsequently stimulated to form a three-dimensional cartilage tissue due to aggregation under an oxygen partial pressure of 21%.
Patent PT-1377314-E (PT)
Title: Monoclonal antibodies to the clfa protein and method of use in treating or preventing infections
Inventor: PATTI JOSEPH M
IPC: A61P31/04
Filed: 2002-01-28
Abstract: Monoclonal antibodies which can bind to the ClfA protein and which are generated from binding subdomains or active fragments of the ClfA protein from Staphylococcus aureus, including the active fragments proteins from its fibrinogen binding domain such as Clf40 protein, the Clf33 protein, or ClfA N3, are provided which can be useful in the treatment and protection against infection from staphylococcal bacteria such as Staphylococcus aureus. In addition, medical instruments can be treated using the monoclonal antibodies of the invention in order to reduce or eliminate the possibility of their becoming infected or further spreading the infection. In particular, the antibodies of the present invention are advantageous because they can prevent adherence of the bacteria to host cells by impairing or inhibiting the ability of S. aureus ClfA to bind to fibrinogen or fibrin, and thus can be utilized in methods or treating or preventing staphylococcal inventions.
Patent PT-1385538-E (PT)
Title: Chimeric vaccines comprising the lumenal domain of lamp-1 or lamp-2
Inventor: AUGUST THOMAS
IPC: A61P31/04
Filed: 2002-04-05
Abstract: The invention provides chimeric proteins and nucleic acids encoding these which can be used to generate vaccines against selected antigens. In one aspect, a chimeric protein comprises an antigen sequence and a domain for trafficking the protein to an endosomal compartment, irrespective of whether the antigen is derived from a membrane or non-membrane protein. In one preferred aspect, the trafficking domain comprises a lumenal domain of a LAMP polypeptide. Alternatively, or additionally, the chimeric protein comprises a trafficking domain of an endocytic receptor (e.g., such as DEC-205 or gp200-MR6). The vaccines (DNA, RNA or protein) can be used to modulate or enhance an immune response against any kind of antigen. In one preferred aspect, the invention provides a method for treating a patient with cancer by providing a chimeric protein comprising a cancer-specific antigen or a nucleic acid encoding the protein to the patient.
Patent PT-1336807-E (PT)
Title: Sealed head for the transfer of a heat transfer medium
Inventor: SZAM PETER
IPC: F26B13/18
Filed: 2003-01-11
Abstract: An insulator (14) has a part that closely and radially surrounds a shaft (3) between seal rings (10,11) and an opening (16) to form a small gap (13) through which oil can flow. The seal rings are exposed to the flowing oil to prevent oil from getting to seals.
Patent PT-1408153-E (PT)
Title: System for feeding combustion air in a soda recovery boiler
Inventor: RUOHOLA TUOMO
IPC: D21C11/12
Filed: 2003-10-08
Abstract: Feeding of combustion air in a soda recovery boiler comprises feeding air into a boiler furnace (7) as primary air jets (5) and auxiliary air jets (6) that are shorter than the primary air jets. Primary air jet(s) is placed between two auxiliary air jets in the opposite direction. Independent claims are also included for: (a) a system for feeding combustion air in a soda recovery boiler, comprising a primary nozzle (3) to produce a primary air jet, and >=2 auxiliary nozzles (4) to produce auxiliary air jets smaller than the primary air jet; and (b) a soda recovery boiler comprising the system for feeding combustion air provided with an air feeding level or a sublevel.
Patent PT-1551868-E (PT)
Title: Factor involved in metastasis and uses thereof
Inventor: KLIPPEL-GIESE ANKE
IPC: C07K14/00
Filed: 2003-10-20
Abstract: The present invention is related to a nucleic acid coding for a factor involved in a biological process, whereby the process is a PI 3-kinase pathway regulated process, preferably a process selected from the group comprising glucose metabolism, amino acid and glucose deprivation processes, diabetes, wound healing, stress response, apoptosis, metastasis, tumorigenesis, cell migration, cell motility in extracellular matrix and cell growth in extracellular matrix, and the factor is a polypeptide comprising an amino acid sequence according to SEQ ID. NO. 1 or a polypeptide having a sequence according to databank entries gi 9506687 or NP_061931, preferably NP_061931.1.
Patent PT-1709279-E (PT)
Title: Shutter comprising a built-in air solar converter
Inventor: CANALETTI JEAN-LOUIS
IPC: F24S10/40
Filed: 2004-12-02
Abstract: The shutter (5) has a rigid frame mounting a double side solar collector, and a cool air inlet on each side of the collector. A heat exchange and air circulation passage communicates with a flexible pipe (26) for diverting the hot air inside a building. The flexible pipe is fixed to the shutter and to a fixed duct (28) integrated to the building and opening within the building.
Patent PT-1698581-E (PT)
Title: Machine, lifting system and machine room-less elevator
Inventor: RUIZ ANTONIO PEREZ
IPC: B66B11/00
Filed: 2005-03-01
Abstract: A machine, lifting system and elevator, wherein the gearless machine comprises a frame (31) and a cylindrical motor (300) having a stator (30) and a rotor (32), wherein:  the stator (30) is a longitudinal shaft;  the rotor (32):  forms the substantially cylindrical outer surface of the motor (300);  is configured to rotate about a rotating shaft parallel to the stator (30);  comprises a traction pulley (321) in a central position configured for hauling a chassis (18, 52, 63) of an elevator car (19) and a counterweight (17, 64) through hauling means (16, 66);  the length of the stator (30) is greater than the length of the rotor (32);  the frame comprises support means (311) spaced a distance coinciding with the first length, configured to carry the motor (300), the motor (300) being rigidly joined to the frame (31) by means of the stator (30).
Patent PT-2004323-E (PT)
Title: Flushing in a multiple loop reactor
Inventor: FOUARGE LOUIS
IPC: B01J8/00
Filed: 2007-03-27
Abstract: The present invention discloses multiple loop reactor wherein one of the settling legs transferring polymer product from one loop to a further loop can be taken out of service or re-opened without interfering with the operation of said multiple loop reactor.
Patent PT-2222289-E (PT)
Title: Treatment of oral pharyngeal dysphagia
Inventor: MILLER KEVIN BURKE
IPC: A23L23/00
Filed: 2008-10-07
Abstract: The invention provides a method of treating oral pharyngeal dysphagia in an individual and related products. One embodiment of the invention comprises administering to an individual an effective amount of a vanilloid receptor 1 (VR-1) agonist or high-affinity partial agonist to promote a swallow reflex.
Patent PT-684835-E (PT)
Inventor: WELLS JAMES A
IPC: A61K38/00
Filed: 1994-02-09
Abstract: We have discovered that growth hormones form ternary complexes with their receptors in which site 1 on the hormone first binds to one molecule of receptor and then hormone site 2 then binds to another molecule of receptor, thereby producing a 1:2 complex. We believe this phenomenon is shared by other ligands having similar conformational structure. Assays based on this phenomenon are useful for identifying ligand agonists and antagonists. Sites 1 and 2 are structurally identified to facilitate generation of amino acid sequence variants of ternary complex-forming ligands. Novel variants of growth hormone, prolactin placental lactogen and other related ligands are provided. As a result of our studies with the ternary complex we have determined that selected antibodies to the receptor for these ligands are capable of acting as ligand agonists or antagonists. Novel growth hormones and novel uses for anti-growth hormone receptor antibodies are described. Methods for inhibiting the growth of breast cancer cells are also described.
Patent PT-823014-E (PT)
Inventor: EUTEBACH PETER
IPC: E05D5/02
Filed: 1995-04-27
Abstract: The invention concerns a frameless glass door with two parallel panes at a spacing from each other and with a peripheral profiled spacer section (3) on the external region. The profiled spacer section (3) tightly surrounds the space between the panes and forms empty spaces (31, 32) for the installation of fittings and/or door locks.
Patent PT-828483-E (PT)
Inventor: ISLAM KHALID
IPC: A61K31/122
Filed: 1996-05-20
Abstract: The present invention concerns the use of puberulic or puberulonic acid as inhibitors of the enzyme iositol monophosphatase (EC 3.1.3.25) and thus useful in the treatment of manic or depressive symptoms.
Patent PT-822364-E (PT)
Inventor: DURIN MICHEL
IPC: H02G3/06
Filed: 1997-07-23
Abstract: A connecting splice for wire cable trough sections is disclosed. The splice comprises two arms (55, 56). The mounting means (57, 58) for the first arm (55) enable independent fastening of the splice on a first section (51, 52). The mounting means for mounting the second arm (56) on a second section (53, 54) comprise at least one resilient hooking means (60) engaging a transverse wire of the second section (54) during the connection of two sections. A cable trough section comprising pre-mounted splices is also disclosed.
Patent PT-914315-E (PT)
Inventor: FASSI ALDO
IPC: C07C229/22
Filed: 1997-05-26
Abstract: PCT No. PCT/EP97/02693 Sec. 371 Date Nov. 30, 1998 Sec. 102(e) Date Nov. 30, 1998 PCT Filed May 26, 1997 PCT Pub. No. WO97/46512 PCT Pub. Date Dec. 11, 1997Stable, non-hygroscopic salts of L(-)carnitine and alkanoyl L(-)carnitines with mucic acid of formula (I) are disclosed wherein the molar ratio between the carnitine moiety and mucic acid is 2:1. A process for producing the salts and solid orally administrable compositions containing same are also disclosed.
Patent PT-906281-E (PT)
Inventor: TOM WITZEL DR
IPC: C07D221/20
Filed: 1997-05-30
Abstract: PCT No. PCT/EP97/02822 Sec. 371 Date Nov. 12, 1998 Sec. 102(e) Date Nov. 12, 1998 PCT Filed May 30, 1997 PCT Pub. No. WO97/46529 PCT Pub. Date Dec. 11, 1997A process for purifying crude piperidines of the formula I where R1 to R4 are C1-C6-alkyl, or R1 and R2 and/or R3 and R4 together are a CH2-chain of 2 to 5 carbons, which comprises, in a first step, removing high-boiling substances and, if present, water from the crude piperidines by distillation; in a second step, adding from 0.01 to 5% by weight, based on the product of the first step, as a reducing agent; and, in a third step, isolating the piperidines by distillation.
Patent PT-980578-E (PT)
Inventor: MADER LEOPOLD
IPC: H01H50/24
Filed: 1998-04-14
Abstract: PCT No. PCT/EP98/02166 Sec. 371 Date Nov. 4, 1999 Sec. 102(e) Date Nov. 4, 1999 PCT Filed Apr. 14, 1998 PCT Pub. No. WO98/50932 PCT Pub. Date Nov. 12, 1998The relay has a T-shaped core and a U-shaped armature, the transverse web of the latter being mounted on the free end section of the core longitudinal limb, and the free ends of its longitudinal arms forming two parallel operating air gaps with respect to the transverse limbs of the core. In this way, particularly simple assembly and an operating air gap with large pole areas can be achieved using a small number of simple parts.
Patent PT-988876-E (PT)
Inventor: KYDO RICHARD ANDREW
IPC: A63F13/12
Filed: 1999-08-20
Abstract: A method of sampling, at a central location, data generated from a number of remote data sources. The method comprises: a) causing those data sources with generated data to implement a local response function; b) transmitting information from the central location to the remote data sources relating to the outcome of the local response function; c) causing those data sources with generated data to determine whether the outcome of the local response function satisfies a predetermined relationship with the information transmitted from the central location, and, if it does, to transmit the generated data to the central location.
Patent PT-1099203-E (PT)
Inventor: ANDERS ARMIN
IPC: G08G1/00
Filed: 1999-07-16
Abstract: From a body located at a distance above the surface of the earth, an image is recorded of a region that is located underneath the body on or above the surface of the earth and that has a diameter of at least one kilometer. The recorded image is fully geocoded and comprises a grid dimension small enough that vehicle densities located in the region can be recognized. The recorded image is evaluated with respect to these vehicle densities and the spatial allocation thereof to the associated roadways. The method is used for acquisition of the state of street traffic over a large area.
Patent PT-1132403-E (PT)
Inventor: JOSE EZQUERRO SAENZ IGNACIO
IPC: A61K48/00
Filed: 1999-11-23
Abstract: Antagonistic synthetic peptides, obtained from TGF beta 1 or from its receptors in the organism, that can be used in the manufacture, both on their own, as well as the gene sequences that encode them and the recombinant systems that express them, in the manufacture of compositions for use in the treatment of liver diseases and more concretely in cases of fibrosis. The said compositions can optionally include mimotopes of the said active peptides.
Patent IE-37061-L (IE)
Title: Polyacrylate salt composition
IPC: A23K1/18
Filed: 1973-01-05
Abstract: 1390565 Polyacrylate compositions NIPPON KAYAKU KK and GLICO CHIKUSAN KK 11 Jan 1973 [14 Jan 1972 20 June 1972] 1574/73 Heading A5B Gastric ulcers in swine are prevented by administration of a polyacrylate salt, e.g. in their feed. Sodium and potassium polyacrylates are specified.
[GB1390565A]
Patent IE-34050-L (IE)
Title: Azepine derivative
IPC: C07D223/28
Filed: 1970-03-09
Abstract: 1310120 Dibenzazepine derivative CIBAGEIGY AG 9 March 1970 [31 March 1969] 11111/70 Heading C2C The novel compound, 10-hydroxy-10,11- dihydro - 5H - dibenz[b,f]azepine - 5 - carboxamide, is prepared by reduction, e.g. with hydrogen in the presence of copper chromite, of 10 - oxo - 10,11 - dihydro - 5H - dibenz[b,f]azepine-5-carboxamide. Pharmaceutical compositions having central depressant and anticonvulsive action, for oral or rectal administration, comprise the above novel compound together with a pharmaceutical carrier.
[GB1310120A]
Patent IE-38914-L (IE)
Title: N-sulphenylated n-methylcarbamidoximes; pesticides
IPC: C07C67/00
Filed: 1974-02-22
Abstract: N-sulfenylated-N-methyl-carbamic acid esters of 2-oximino-alkanecarboxylic acid nitriles of the formula CH3 R1-C=NOC-N ANGLE (I) ¦ PARALLEL CNOSR2 in which R1 is alkyl, cycloalkyl, or alkyl-substituted cycloalkyl, and R2 is a C1-8 aliphatic radical substituted by halogen; aryl; aryl substituted by halogen, methyl, trifluoromethyl or nitro; or the radical of the formula R3 ¦ R4-SO2-N- wherein R3 is alkyl, and R4 is alkyl, haloalkyl, aryl, or aryl substituted by halogen, methyl or nitro, WHICH POSSESS INSECTICIDAL, ACARICIDAL, FUNGICIDAL AND BACTERICIDAL PROPERTIES.
[US3939192A]
Patent IE-900511-L (IE)
Title: Pasteurized, purified von Willebrand factor concentrate and¹a process for the preparation thereof
IPC: C07K1/18
Filed: 1990-02-13
Abstract: A method for the preparation of a concentrate of von Willebrand factor is described, in which a solution of a complex of this factor and factor VIII:C is, where appropriate, pasteurised and treated with an anion exchanger, the von Willebrand factor not being bound.
Patent IE-900516-L (IE)
Title: Magnetic key operated lock
IPC: E05B47/00
Filed: 1990-02-13
Abstract: In a magnetic key operated lock, a slide member carries a plurality of wheels in which are mounted magnetic pins. The position of the pins forms part of a code of the lock. The wheels are caused to rotate by insertion of a code changing key, which has a code for unlocking the lock, and moving the slide member. As the slide member moves, one of the pins which is repelled by the particular code changing key abuts a stop, which thus causes the respective wheel, and so the other wheels, to rotate. By having wheels of two different diameters, the smaller wheels can be made to rotate more than once before a code is repeated. The stops are formed by pressing a tang from a stationary wall in the lock.
Patent IE-37611-L (IE)
Title: Organo-tin mercaptides; vinyl resin stabilisers
IPC: C08L33/00
Filed: 1973-04-12
Abstract: Unsaturated organo-tin mercaptides, useful as stabilisers for halogenated vinyl resins, are obtained by reacting x mols of a mercaptocarboxylic acid HSXCOOH with y1 mols of an alcohol HOYOH or mixture thereof with y2 mols of alcohol HOY'OH and/or y3 mols of alcohol ROH, where X is C1-4 alkylene or phenylene, Y is C1-10 alkylene or cycloaliphatic of five or six ring carbons, each with ethylenic and/or acetylenic bonds but not more than two of each type of bonds, Y' is C1-10 alkylene or cycloalkylene with five or six ring carbons, R is C1-8 alkyl or alkenyl, cycloalkyl or cycloalkenyl with five or six ring carbons, or phenyl (C1-4) alkyl, with x, y1, y2 and y3 having specified inter-relationships, to form an intermediate, and reacting the intermediate with a tin component, which is z1 mols of diorgano tin derivative R1 R2 SnO or R1 R2 SnCl2, or mixture thereof with z2 mols of mono-organo tin derivative which is a stannoic acid monomer or polymer (R1SnO1.5), R1SnCl3, R1Sn(OH)Cl2 or R1SN(OH)2Cl where R1 and R2 are C1-10 alkyl and x, z1 and z2 have specified interrelationships.
[US3818062A]
Patent IE-33075-L (IE)
Title: Benzodiazepines
IPC: C07D243/26
Filed: 1969-05-05
Abstract: (A) Cpds. of the general formula (I) R = H or (2-7C) lower alkanoyl (B) Salts of I. Sedatives. 4.69N NaOEt/MeOH (0.9 ml) was added to III (1 g.) in DMF (15 ml), stirred 0.5 h., and ethylene oxide (0.45 g.) in DMF (5 ml) added. The mixture was stirred 2 h. at 25 deg., 1 h. at 60 deg., evapd. in vac., and succinic anhydride (1.5 g.) in PhMe (50 ml) added. After refluxing 3 h., the mixture was cooled in ice, basified (NH4OH) and sepd. The H2O phase was treated with 3N-NaOH (5 ml), stirred 30 mins., acidified (cHCl), and basified (NH4OH), extd. with CH2Cl2, washed with brine (50 ml), dried and evapd. The residue in PhH (15 ml) was filtered through SiO2 (50 g), eluted with PhH (200 ml) and EtOAc (250 ml), the EtOAc evapd., dissolved in EtOH (5 ml), and HCl-EtOH added, giving I-HCl (R=H), m.p.195-7 deg.
[FR2007969A1]
Patent FI-812604-L (FI)
Inventor: RUSHFORD CALVIN
IPC: B22D11/14
Filed: 1981-08-24
Abstract: An oscillating cooled mold assembly for the continuous, high-speed casting of metallic strands or rods, especially upcasting strands or rods of copper alloys such as brass, has a hollow die in fluid communication with a melttypically held in a casting furnace. A coolerbody surrounds the die in a tight-fitting relationship to form a solidification front in the melt as it advances through the casting zone of the die. The strand or rod formed from the solidified melt is pulled through the die whilethe mold oscillates in a direction substantially parallel to the direction oftravel of the rod.
Patent FI-814140-L (FI)
Inventor: LUNDBERG LARS U SON
IPC: B30B9/30
Filed: 1981-12-22
Abstract: A device for dry storage of garbage under refrigerator temperature conditions in a cabinet (1, 8, 9, 10, 11) which includes a compacting device (12-19) for compacting the garbage, a storage-space (7) for receiving a garbage container (5) and a throwing-in door (3) for the introduction of the garbage in the garbage container. The characteristic feature of the invention is a refrigerating appliance (22, 29) for cooling the air in the storage-space (7) down to the refrigerator temperature.
Patent FI-821582-L (FI)
Inventor: KURANDT HANS-FRIEDRICH
IPC: C04B11/26
Filed: 1982-05-05
Abstract: A process for preparing shaped articles from waste gypsum from wet-process phosphoric acid production comprises: (1) mixing wet calcium sulfate hemihydrate with 0.5-20% by wt. of calcium hydroxide or calcium oxide, (2) adjusting the total water content of said mixture to 20-40% by wt., if necessary, and (3) molding shaped articles from said mixture by compression molding. The shaped objects so prepared have a low density and relatively high compressive strength.
Patent FI-821636-L (FI)
Inventor: SLINNER EDWARD ALBERT
IPC: B65B7/18
Filed: 1982-05-10
Abstract: A gable-topped carton blank is cut from paperboard coated on both faces with thermoplastics. In the top closure, a loop of sub-panels provides a sealing fin. Each of two opposite sub-panels is folded inwardly upon itself and one is opened-out in forming a pouring spout. To reduce the tendency for the internal surface middle zone of this sub-panel to adhere to the internal surfaces of two other upper sub-panels during heat-sealing, these latter surfaces are formed in the blank with embossed recesses corresponding somewhat in position with recesses in sealing jaws.
Patent FI-830404-L (FI)
Inventor: ZIERENBERG BERND
IPC: A61K9/70
Filed: 1983-02-07
Abstract: A novel process for the preparation of a pharmaceutical preparation in the form of an polyacrylate film for long-term transdermal administration of systemic pharmaceuticals comprising forming a homogeneous solution of an effective amount of a systemically acting pharmaceutical and a freeze-dried latex of a polyacrylate copolymer of methyl and/or ethyl esters of acrylic acid and methacrylic acid formed by emulsion polymerization and having an average molecular weight of about 800,000 in at least one organic solvent, forming a thin layer of the said solution and drying the layer to form a polyacrylate film and the film product produced by the said process.
Patent IE-841071-L (IE)
Title: Self-protected thyristor
IPC: H01L21/332
Filed: 1984-05-01
Abstract: The present invention is directed to a thyristor self-protected against overvoltage by the avalanche mechanism, the protection resulting from a well cut in the top surface of the thyristor and extending through one base region of the thyristor and forming two regions of opposite conductivity type at the bottom of said well, and to the process for making the thyristor.
[US4516315A]
Patent IE-781083-L (IE)
Title: Facsimile installations
IPC: H04N1/387
Filed: 1978-05-30
Abstract: The present invention relates to a facsimile transmission installation adapted to allow rapid transmission of the contents of forms. In accordance with the invention, various types of blank forms are memorized and the transmission equipment includes a comparator connected to a memory and to an analysis circuit and allows the transmission of a facsimile signal which represents only the data added on the analyzed filled-in form and the reception equipment includes a text regenerator which operates from a transmitted facsimile signal and from a signal which comes from its memory.
[US4187520A]
Patent IE-41612-L (IE)
Title: Triazolo-isoquinolines
IPC: C07D221/00
Filed: 1974-05-24
Abstract: Antifertility methods employing a triazolo-isoquinoline derivative selected from 2-phenyl-5,6-dihydro-s-triazolo[5,1-a]isoquinoline of formula 2-PHENYL-S-TRIAZOLO[5,1-A]ISOQUINOLINE OF FORMULA AND A PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALT THEREOF, TOGETHER WITH ANY SUITABLE PHARMACEUTICAL CARRIER.
[US3895113A]
Patent IE-791111-L (IE)
Title: New antibiotics.
IPC: A23K20/195
Filed: 1979-08-08
Abstract: The antibiotics S 54832/A-I, S 54832/A-II, S 54832/A-III and S 54832/A-IV are obtained from a new Micromonospora globosa strain.
[US4478831A]