baber/WOPTO huggingface dataset:
Patent SG-95491-G (SG)
Title: 4-nitrogen substituted isoquinolinol compounds having cardiotonic,phosphodiesterase fraction iii inhibiting properties and/or renal vasodilating properties
IPC: C07D491/056
Filed: 1991-11-08
Abstract: Substituted 3-isoquinolinol compounds of the general formula <CHEM> that exhibit cardiotonic and/or phosphodiesterase fraction III inhibiting properties and/or renal vasodilating are pharmacologically active in the treatment of cardiac conditions. Methods for synthesizing and using those compounds are described.
Patent IE-850307-L (IE)
Title: Diffusion-coated multiple-units dosage form
IPC: A61K9/22
Filed: 1985-02-08
Abstract: In an oral pharmaceutical controlled releasable multiple-units formulation, individual units containing an active substance are coated with a substantially water-insoluble, but water-diffusible controlled release coating which includes 1) an inner film layer which causes adhesion between the units at elevated temperatures, comprising a water-dispersible film-forming agent, and 2) an outer film layer comprising a water-based film-forming agent which prevents adhesion between the units at elevated temperatures and imparts flowability to the units. <??>The inner film layer may additionally comprise a substance which is capable of forming a continuous phase. <??>By subjecting the thus coated units to heating to accelerate the formation of a continuous phase of the film-forming agent of the inner layer and optionally also of the additional substance, a coating is formed which substantially does not change its diffusion characteristics in the course of time. 
[EP0153105A2]
Patent IE-32806-L (IE)
Title: Sustained release drug composition
IPC: A61K9/24
Filed: 1969-05-07
Abstract: 1,263,392. Sustained-release medicaments. AMERICAN HOME PRODUCTS CORP. 13 May, 1969 [21 May, 1968; 13 Feb., 1969], No. 24256/69. Heading A5B. A delayed or sustained-release medicament is made by mixing together a drug a carboxy vinyl polymer and polyethylene glycol (P.E.G.) and tableting this mixture together with conventional tablet ingredients. Suitable carboxy vinyl polymers are acrylic acid polymers crosslinked with 0.75 to 2% of a polyallyl ether of sucrose having an average of about 5.8 allyl groups per molecule of sucrose. Suitable P.E.G.'s are those of molecular weight 1000 to 20,000 especially 4000 to 6000. Reference is made to compositions containing numerous known drugs.
[GB1263392A]
Patent IE-39104-L (IE)
Title: Fire screening glazing panel
IPC: E06B7/28
Filed: 1974-03-27
Abstract: 1451931 Laminates GLAVERBEL-MECANIVER 27 March 1974 [30 March 1973 17 Sept 1973 (2)] 15466/73 43536/73 and 43538/73 Heading B5N A fire screening glasing panel comprises a first structural ply which is a vitreous sheet and at least one other structural ply and sandwiched between the plies, at least one plastics membrane, there being on opposite sides of the membrane(s) layers at least one of which is composed of or incorporates intumescent material, e.g. hydrated metal salt. When sufficiently heated the intumescent material becomes converted to form a thermally insulating barrier or barriers which is or are opaque or of greatly reduced infra-red radiation transmitting power as compared with the or each such layer before such conversion. The hydrated metal salt may be an aluminate, plumbate, alum, stannate, borate, phosphate or alkali metal silicate. The hydrated metal salt is preferably an alkali metal or aluminium salt. The panel may be transparent, translucent or opaque. A protective stratum may be provided between the vitreous sheet and adjacent intumescent layer, and may be a coating or sheet of plastics material, e.g. polyvinyl butyral, polyurethane or acrylic acid/methyl acrylate copolymer, or coating of anhydrous metal compound, e.g. anhydrous aluminium phosphate or zirconium, indium, tin or titanium oxide. The plastics membrane may be of polyvinyl butyral, polyvinyl chloride or polyurethane. The other ply may also be a vitreous sheet and at least one vitreous ply may have been chemically tempered, e.g. in bath of potassium nitrate. Alternatively the other ply may be a sheet of plastics material. A panel in which both outer plies are of vitreous material may be bonded to a polyurethane sheet via a layer of polyvinyl butyral. The layers may be bonded together with the application of heat and pressure or by means of a frame.
[GB1451931A]
Patent IE-820770-L (IE)
Title: Process.
IPC: C07C51/00
Filed: 1982-03-31
Abstract: A new process for the preparation of the d-2-(6-methoxy-2-naphthyl)-propionic acid of formula <IMAGE> I which comprises resolving a racemic mixture of the d- and 1-2-(5-halo-6-methoxy-2-naphthyl)-propionic acids of formula <IMAGE> II wherein halo stands for a halogen atom, recovering the d-isomer and subjecting this isomer to catalytic dehalogenation. Compound I is obtained in very high yields and with a high purity degree.
[US4423244A]
Patent IE-34305-L (IE)
Title: Semiconductor chip bonding
IPC: H01L21/60
Filed: 1970-06-15
Abstract: An apparatus for attaching semiconductor chips to gold pads is described as comprising a stainless steel hot stage mounted on top of a heater block having a temperature of approximately 300.degree. C. with a platinum ribbon heater or an RF heater element protruding through a hole in the hot stage and flush with the top surface thereof so as to provide a local hot spot smaller than the gold pads to which the semiconductor chips are to be attached. A current passed through the platinum causes heating to a temperature sufficient to eutectically bond the chip to the gold pad. An inert atmosphere is provided during the bonding operation to enhance the accuracy and reproducibility of the bond.[US3617682A]
Patent IE-32868-L (IE)
Title: Halogenated steroids
IPC: C07C/
Filed: 1969-06-09
Abstract: 1,244,560. 4,7 - Dichlorosteroids. F. HOFFMANN-LA ROCHE & CO. A.G. 9 June, 1969 [8 Jan., 1969], No. 29012/69. Heading C2U. The invention comprises steroids of formula wherein R 1 is F, Cl, Br or C 1-8 alkyl; Q is oxo, OH, C 2-8 alkanoyloxy or C 2-4 1<SP>1</SP>,2<SP>1</SP>-alkylenedioxy; and M is a structure of formula wherein R 2 is H or F; R 3 is H, OH, C 1-8 alkoxy, C 2-8 alkanoyloxy, COCHF 2 , COCHCl 2 or C 1-8 alkyl; and R 4 is H, C 1-8 alkyl or C 1-8 alkylidene; or R 3 and R 4 together represent a 16α,17α- [1<SP>1</SP> - (C 1-8 alkyl) - C 1-8 alkylidenedioxy] group; X is a #<SP>1</SP> - unsaturation or a 2 - chloro or 1α,2α- methylene substituent; and n is 0 or 1; or M is a structure of formula wherein R 5 is H or C 2-8 alkanoyl; R 6 is H, C 1-8 alkyl, C 2-8 alkenyl, C 2-8 alkynyl, C 2-8 haloalkenyl or C 2-8 haloalkynyl; R 7 is H or Me; X<SP>1</SP> is a #<SP>1</SP>-unsaturation or a 2-chloro substituent; n is 0 or 1; and Y is CH 2 , CH(#OH), CH(α-OH) or CO; with the proviso that when X<SP>1</SP> is a #<SP>1</SP> - unsaturation and n is 1, then R 7 is Me; or M is a structure of formula wherein R8 is H, F, Cl or Br; R 9 is H, OH, OPO(OH) 2 , an alkali metal salt of OPO(OH) 2 or C 2-8 alkanoyloxy; R 10 is H, α-OH, C 1-8 alkylidene, α-F, α-Cl, α-CH 2 Cl, α-CH 2 F or α- or #-C 1-8 alkyl; R 11 is OH or C 2-8 alkanoyloxy; or R 10 and R 11 together represent a 16α,17α- [1<SP>1</SP> - (C 1-8 alkyl) - C 1-8 alkylidenedioxy] group; or R 9 and R 11 together represent a 17α,21- [1<SP>1</SP> - (C 1-8 alkoxy) - C 1-8 alkylidenedioxy] group; X<SP>1</SP> is a #<SP>1</SP>-unsaturation or a 2-chloro substituent; n is 0 or 1; Z is CO, CH(α-OH), CH(#-OH), CH(α-OSO 2 R 12 ) where R 12 is C 1-8 alkyl or ptolyl, or when R 8 is H and R 9 is other than H, Z may be CH 2 , or when R 8 is Cl Z may be CH(#-CI), or Z and R 8 together represent a -CH = or -CH(α-epoxy) grouping. Preparation of the above compounds is by reaction of chlorine with compounds of formula (wherein M<SP>1</SP> is as defined above for M except that no #<SP>1</SP>-unsaturation may be present) followed when required by conventional conversions of the 3-oxo group into other values of Q defined above and/or by 1,2-dehydrogenation. The inventive compounds are stated to possess progestational, cortieoid, antiinflammatory and thymolytio activities, and may be made up with carriers into pharmaceutical compositions for oral, parenteral and rectal administration.
[GB1244560A]
Patent IE-800887-L (IE)
Title: Haymaking machine
IPC: A01D78/00
Filed: 1980-05-01
Abstract: A hay-gathering machine for pulling windrows of hay, turning the hay over, and scattering it, having a rake-wheel comprising a plurality of tine-carriers radially directed outwards from an almost vertically-pointed swivel pin, wherein the tine-carriers at their outer ends are provided with rake-tines. At the end of each tine-carrier, which is directed toward the swivel pin of the rake-wheel, there is attached at least one control lever, which, for the pulling of windrows, is connected with a first open control channel in a tensional or a form-locking, or in a purely form-locking manner. The tensional or form-locking connection of the control lever with the first open control channel is made by means of a spring or the like, while the purely form-locking engagement of the control lever into the first control channel is made by means of cooperation of the roller on the control lever with a guide way which is parallel to the first control channel. By means of a second control channel, which is displaceable in longitudinal direction to or around the swivel pin of the rake-wheel, the tines on the tine-carriers are changed into a fixed position almost vertical to the ground.
[US4345422A]
Patent IE-780901-L (IE)
Title: Tetrazolyl-piperidinyl amides
IPC: A61P25/04
Filed: 1978-05-04
Abstract: N-Phenyl-N-(4-piperidinyl)amides have the following formula <IMAGE> in which the substituents are defined in Claim 1; the compounds can also be present as acid addition salts. The compounds of the formula I, in which Z is oxygen, are prepared by reacting a corresponding 4,5-dihydro-1H-tetrazol-5-one with a corresponding N-phenyl-N-(4-piperidinyl)amide. Compounds of the formula I, in which Z = O, are likewise obtained by N-acylating a corresponding 4-piperidinamine. Compounds in which Z = S are prepared from compounds of the formula I, in which Z = O, by reaction with a sulphurating agent. Pharmaceutical compositions having an analgesic effect contain, as the active compound component, at least one novel compound of the formula I or a pharmaceutically acceptable acid addition salt thereof.
[GB1598872A]
Patent IE-45414-L (IE)
Title: Manufacture of phenol resin foam sheets
IPC: B29L9/00
Filed: 1977-05-05
Abstract: A method for the continuous fabrication of blankets or sheets of expanded phenolic resin displaying a hard skin on each of their sides, according to which a mixture, comprising in particular a resole resin, a blowing agent and a hardening catalyst is placed on an essentially flat surface of a moving conveyor, is completely expanded, and is conformed eventually between two parallel surfaces entrained in the same direction, the second surface being located above and substantially parallel to and able to move at the same speed as the moving surface, characterized in that, in a first stage, after having been distributed at the surrounding temperature and in the liquid state along the whole width of the surface of the transport component, in such a way so as to comprise a blanket of expandable liquid mixture essentially uniform in thickness, the expandable mixture is conveyed in the open air towards the conformation surfaces while being submitted to a heating so that it expands, the degree of heating and the length of the path in the open air being chosen in a way that the upper skin loses its stickiness before the complete expansion of the mixture and that after the complete expansion, the obtained expanded mass reaches an immediate hardening state, the upper skin remaining supple and unsticky; and then the expanded mass is formed by the exertion of pressure on its free side at the time of entry between the conformation surfaces, thus reducing the thickness of the mass to its definitive value; and finally the hardening of the resin is completed by maintaining the pressure and the heat during the passage between the conformation surfaces.
[US4252515A]
Patent FI-820189-L (FI)
Inventor: NIKOLICH MILOVAN
IPC: B25C1/08
Filed: 1982-01-21
Abstract: A self-starting portable tool comprises a cylinder (104) in a housing (102), a piston (130) being mounted in said cylinder (104), means (164) for igniting and exploding a mixture of fuel and air in a combustion chamber (120) to drive said piston (130) to operate a working member (132), return means for causing said piston (130) to move upwardly from a lowermost position to an uppermost position of rest including outlet means (156) in said cylinder (104) between its ends. Thereby, a portion of combustion gases is forced to exhaust from said combustion chamber (120) to ambient atmosphere and a reduction in temperature of the combustion gases remaining in the combustion chamber (120) is caused. Said return means further include bumper means for initially moving said piston (130) upwardly from said lowermost position, said combustion chamber (120) above said upper face (130A) of said piston (130) being out of communication with ambient atmosphere during the further return of said piston (130) which return is substantially caused by producing an upwardly acting pressure differential on the upper and lower faces (130A, 130B) of said piston (130) induced by the reduction in temperature of the combustion gases above the upper piston face (130A).
Patent FI-831139-L (FI)
Inventor: ANDRE JACQUES
IPC: F24H9/18
Filed: 1983-04-05
Abstract: 1. Device for tightly mounting heater tubes (4) in a flange (2) surrounding a passage (3) in a wall of a container (1) for liquids, comprising a plug (9) of elastomeric material having a body (10) fitted in the flange (2), an outer surface (13) and an opposite inner surface, in which are made holes (12) for the passage of the heater tubes (4) therethrough, and further having an outer collar (14) bearing on to the outer surface of the flange (2) and a counterflange (16) of a rigid material in which are made holes (18) for the passage of outer parts (5, 6) of the heater tubes (4) therethrough bearing on to the outer surface of the body (10) of the plug (9), characterized in that the counterflange (16) has a diameter sufficient to cover and press at least an annular portion of the outer collar (14) on to the outer surface of the flange (2), while the inner surface of the body (10) of the plug (9) is free of any compression.
Patent FI-831273-L (FI)
Inventor: AIGNER KARL
IPC: A61M25/00
Filed: 1983-04-15
Abstract: A perfusion catheter, designed as a double catheter which includes a splint catheter (1) and a mounted second catheter tube (3), which is shorter than the splint catheter (1) and which branches off from splint catheter (1). The splint catheter includes an attached shunt tube (2) and at least one lateral opening (4). A solid rod (7) is inserted into the splint catheter (1) from its back end so as to temporarily close the lateral opening(s) (4) and the shunt (2). The catheter is particularly useful for the isolated perfusion of the liver.
Patent IE-37696-L (IE)
Title: Barley treatment for the preparation of worts
IPC: C12C7/00
Filed: 1972-07-26
Abstract: 1403391 Wort manufacture GRANDES MALTERIES MODERNES, GROUPEMENT D'INTERET ECONOMIQUE TEPRAL AND POLLOCK INTERNATIONAL Ltd 25 July 1972 [26 July 1971] 34824/72 Heading C6E Wort is made by subjecting barley to at least one treatment of thoroughly wetting with water followed by exposure to air (the temperature and time of the treatment being chosen to cause chitting of the barley), then rolling and grinding the chit malt and extracting with a mixture of hot water and malt, the amount of malt being 10-40% w/w on a solids basis of the dry weight of chit malt and malt, and separating the wort so produced. Wetting may be achieved by steeping for 1-12 hours at #45 C and air exposure for 5-24 hours at 10-40C. After exposure the barley may be resteeped for 0.5-6 hours followed by air exposure at 10-40C for 1-20 hours. The extraction of the chit malt may be performed in the presence of an amylase, a protease and/or a #-glucanase. The barley is preferably at least partially dehusked. Giberellic acid may be added during or after the first steeping. The chit malt may be stored at low temperature, dried with air so that the grain temperature does not exceed 45C, or freeze-dried, after rolling but before grinding.
[GB1403391A]
Patent IE-861159-L (IE)
Title: Expanding memory capacity
IPC: G06F12/06
Filed: 1986-05-01
Abstract: The invention includes one or more circuit cards, each of which can be plugged into a data processing system and each of which can have multiple banks of memory thereon. In a preferred embodiment, a system can have up to two cards and each card can have one, two, or four banks of memory located thereon. In addition each circuit card includes signal generating circuitry which generates a plurality of electrical signals, which signals, when considered together, represent a code that indicates the amount of memory located on the circuit card. Further, in addition, each circuit card has combining circuitry thereon which is connected to receive the last mentioned coded signals as well as coded signals from a second circuit card if the same be plugged into the data processing system. The combining circuitry combines the two sets of coded signals to provide a resultant set of coded signals which are indicative of the total amount of memory on the two cards and the addressable location of such memory. The data processing system with which the circuit cards are used provides the circuit path to connect the circuit cards.
Patent IE-34591-L (IE)
Title: Indolizine derivatives.
IPC: C07D213/55
Filed: 1970-09-09
Abstract: 1,268,424. Indolizine derivatives. BEECHAM GROUP Ltd. 18 Sept., 1970 [4 Oct., 1969], No. 48856/69. Heading C2C. The invention comprises compounds of formulae the pharmaceutically acceptable salts and esters of I, and the esters and salts of II, wherein R and R<SP>2</SP> are each C 1-6 alkyl, and R<SP>3</SP> is aryl or C 1-6 alkyl. These compounds are prepared by reacting 2-formylpyridine with Ph 3 P : CRCO 2 Et to give 2-(2-carbethoxyalk-1-enyl)pyridine, hydrogenating this (H 2 /Pd-C) to 2-(2-carbethoxyalkyl)pyridine, reacting with (e.g.) BrCH 2 Ac to give 1-acetonyl-2-(2-carbethoxyalkyl)pyridinium bromide which is treated with a base to give II, esterifying the latter and reacting the ester with a reactive derivative of R<SP>3</SP>CO 2 H, and optionally hydrolysing the ester of I thus obtained. Therapeutic compositions for oral or parenteral administration comprise compounds I (above), and their pharmaceutically acceptable salts and esters, which have analgesic and anti inflammatory activity.
[GB1268424A]
Patent IE-33079-L (IE)
Title: Epoxy carboxylic acids
IPC: C07D303/32
Filed: 1968-12-16
Abstract: 1,259,947. Epoxycarboxylic acids and derivatives thereof. F. HOFFMANN-LA ROCHE & CO. A.G. 12 Dec., 196 [18 Dec., 1967], No. 59073/68. Heading C2C. Epoxycarboxylic acid derivatives of the formula wherein R and R 1 are C 1-6 alkyl groups, A is -CO.OR 2 or -CO.NR 3 R 4 and R 2 is hydrogen, C 1-6 alkyl, phenyl or a di(C 1-6 alkyl)amino- C 1-6 alkyl group and R 3 and R 4 are C 1-6 alkyl groups or together complete a 5- or 6-membered heteromonocyclic ring which may contain a further N or an O or S atom, are prepared by epoxidizing an ester of the formula heating the resultant epoxide of the formula to at least 120‹ C. to obtain a ketone of the formula and reacting the latter either with a phosphonium salt of the formula in the presence of a strong base, or with a phosphate of the formula (R 1 O) 2 PO.CH 2 A<SP>1</SP> in the presence of a strong base and an inert organic solvent and, if required, saponifying a product containing an alkoxycarbonyl group to obtain the free acid, A<SP>1</SP> representing -CO.OR<SP>1</SP> 2 or -CONR<SP>3</SP>R<SP>4</SP> where R<SP>1</SP> 2 is C 1-6 alkyl, phenyl or a di(C 1-6 alkyl)amino-C 1-6 -alkyl group, R<SP>1</SP>, R<SP>11</SP> and R<SP>111</SP> representing C 6-20 aryl, C 7-20 aralkyl or C 1-20 alkyl groups and X- being the anion of a mineral acid. The epoxidation step may be effected using a carboxylic peracid or H 2 O 2 at 0-60‹ C. The decarboxylation of the ester to the ketone may be carried out in the presence of an aluminium tri-C 1-7 -alkoxide as catalyst. Suitable strong bases for use in the last reaction step are alkali metal hydrides, amides, alkoxides and alkyls. Examples describe the preparation of the methyl and ethyl esters of 3,7,11-trimethyl - 10,11 - epoxy - 2,6 - dodecadienoic acid and the methyl ester of 3,11-dimethyl-7- ethyl - 16,11 - epoxy - 2,6 - tridecadienoic acid. Reference has been directed by the Comptroller to Specifications 1,209,903, 1,209,905 and 1,209,190.
[GB1259947A]
Patent IE-811524-L (IE)
Title: Foamed plastic laminates
IPC: B32B19/02
Filed: 1981-07-07
Abstract: Laminated foamed plastics articles, especially polyurethane and polyisocyanurate rigid foam panels, are faced with a composite layer of vermiculite lamellae and metal foil, especially aluminum foil. The vermiculite lamellae are preferably size-graded to below 50 microns and form a coating on the metal foil which has a thickness preferably below 50 microns. The laminated articles have good fire resistance properties.
[US4366203A]
Patent IE-36828-L (IE)
Title: Oil pressure tank
IPC: F15B1/08
Filed: 1972-11-09
Abstract: 1358088 Hydraulic accumulators PIRELLI GENERAL CABLE WORKS Ltd 25 Oct 1972 [18 Nov 1971] 53592/71 Heading F1D A hydraulic accumulator comprises a vessel 10, Fig. 1, for receiving oil under pressure, containing a stack of gas-filled cells 12 with spacing means 14 between the cells to facilitate the escape of gas from between the cells during degassing. The spacers may comprise rings, Fig.2, with radial holes 18, flat discs with slots, Fig.3, (not shown), or plain or corrugated strips. Alternatively the faces of the cells may be profiled with spiral corrugations, raised rims or bosses.
[GB1358088A]
Patent IE-781624-L (IE)
Title: Absorbant materials
IPC: A61L15/24
Filed: 1978-08-09
Abstract: A method of manufacturing absorbent structures e.g. menstrual towels, nappies, surgical dressings and wiping towels, wherein a liquid- absorbing material e.g. in the form of a powder, is secured to a support e.g. a film or fibrous pad by depositing a binding agent for example poly(vinyl alcohol), particularly in the form of an aqueous solution or dispersion. In one procedure after the liquid-absorbing material and the binding agent have been applied to one pad, a second pad is applied to form an integral structure with the binding agent and in another procedure the liquid-absorbing material is incorporated between two pads, and a liquid binding agent is applied to the external surface of one pad and percolates through to form an integral structure.
[GB2004201A]
Patent IE-881889-L (IE)
Title: Method for preserving transplantable sheets of epithelium¹cultured in vitro
IPC: C12N5/071
Filed: 1988-06-22
Abstract: A process for preserving cultured epithelial sheets by incubating the sheets at room temperature in media with a glycerol or dimethylsulfoxide as cryopreservant for a predetermined period of time and then freezing the cultured sheets. The cooling gradient is characterized as having a lower initial rate of cooling followed by a higher rate of cooling.
[EP0296475A1]
Patent IE-40034-L (IE)
Title: Preparing beads of urea-formaldehyde resin
IPC: C08J3/16
Filed: 1974-09-24
Abstract: A process of preparing beads of urea-formaldehyde resin in which disperse particles of an aqueous urea-formaldehyde syrup are converted to hard polymer and azeotropically dehydrated. The aqueous syrup must have a solids content of at least 65% by weight and the mol ratio of formaldehyde to urea must be within the range of 1.9 - 2.3 to 1.
[US3895826A]