baber/WOPTO huggingface dataset:
Patent CA-2962905-A1 (CA)
Inventor: GRAMMENOS WASSILIOS
IPC: C07D231/22
Filed: 2015-10-05
Abstract: The present invention relates to a process for preparation of intermediates (Z,2E)-5-hydroxy-2-methoxyimino-N-methyl-pent-3-enamides from 4-substituted 5-meth-oxyimino-2H-pyran-6-ones and their processing for example to (Z)-5-cyclyloxy-2-[(E)-methoxyimino]-3-methyl-pent-3-enic acid methyl amides. The invention also relates to a process for preparation of 4-substituted 5-imino-2H-pyran-6-ones and to novel intermediates for the preparation of fungicidal (Z)-5-cyclyloxy-2-[(E)-methoxyimino]-3-methyl-pent-3-enic acid methyl amides.
Patent CA-2963171-A1 (CA)
Inventor: CAI DENGKE
IPC: F21V9/40
Filed: 2014-10-08
Abstract: Materials and optical components formed thereof that are suitable for use in a lighting apparatus to impart a color filtering effect to visible light. At least a portion of such an optical component is formed of a composite material comprising a polymeric matrix material and an inorganic particulate material that contributes a color filtering effect to visible light passing through the composite material, and the particulate material comprises a neodymium compound containing Nd3+ ions.
Patent CA-2964428-A1 (CA)
Inventor: HOMEDES-BEGUER JOSEP
IPC: A61P19/02
Filed: 2015-10-13
Abstract: The present invention refers to the use of the compounds E-6087 in a weekly dosage regime for the treatment of pain and inflammation associated to a degenerative joint disease such as osteoarthritis or a condition associated to any such disease such as lameness. The present invention is directed to the treatment of mammals, preferably of dogs.
Patent CA-2964561-A1 (CA)
Inventor: ACKROYD DENNIS D
IPC: D02G3/36
Filed: 2015-10-13
Abstract: A hybrid yarn and a fabric including the hybrid yarn are provided. The hybrid yarn is formed of a plurality of fibers of a plurality of different fiber compositions. The different fiber compositions are interspersed throughout the yarn. The yarn may be formed using fibers made of the same material or a plurality of different materials. The different fiber compositions may include fibers of three or more different cross sections, fibers made of different materials or a combination of the two. The materials may be synthetic and/or natural materials. The yarn may be constructed to impart selectable functional characteristics to a fabric without the need to include chemicals to impart those characteristics. Fabrics made with the hybrid yarn will have selectable functional features and also be of lighter weight than previously possible. Hybrid spinnerets may be used to produce hybrid yarns with three or more different fiber cross sections.
Patent CA-2968174-A1 (CA)
Inventor: VERHEY LEE ANDREW
IPC: B62D33/02
Filed: 2017-05-24
Abstract: According to some embodiments, a tank car comprises a tank; a top platform coupled to a top of the tank comprising a walking surface; a walkway platform extending longitudinally between an end of the tank and the top platform comprising a walking surface disposed above a line tangent to the top of the tank; and a closure plate coupled to an end of the walkway platform proximate to the top platform. The closure plate extends below the walkway platform to cover access to a space between the walking surface of the walkway platform and the top of the tank.  In particular embodiments, the top platform comprises a first and second handrail assembly and a space between the handrail assemblies for accessing the walkway platform. The closure plate covers access to the space between the handrail assemblies and below the walkway platform.
Patent CA-2970195-A1 (CA)
Title: Method and apparatus for randomizing computer instruction sets, memory registers and pointers
Inventor: MAJUMDAR ARUN
IPC: G06F21/71
Filed: 2015-12-16
Abstract: Described herein is a method and apparatus to randomize instruction sets, memory registers, and pointers to increase computer security by increasing resource commitment requirements for malicious software, malicious computer users, or reverse engineers to understand the meaning of the new instruction sets, memory registers, and pointers.
Patent CA-2971826-A1 (CA)
Inventor: YACOBY-ZEEVI ORON
IPC: C07D221/18
Filed: 2015-12-23
Abstract: La présente invention concerne des formes cristallines solides de la base libre d'apomorphine ou un hydrate, un solvate ou des co-cristaux associés. Les formes cristallines de l'apomorphine peuvent être avantageuses par rapport aux formes amorphes, par exemple les sels amorphes comme les sels d'addition acide de l'apomorphine, à cause de leur plus grande stabilité et/ou des propriétés pharmacologiques améliorées, par exemple, la réduction des réactions indésirables au site d'administration.<i /> <i /> L'invention concerne en outre des formulations liquides obtenues en dissolvant lesdites formes cristallines de l'apomorphine dans un solvant, ainsi qu'un procédé pour le traitement d'un trouble neurologique ou du mouvement, par exemple la maladie de Parkinson, ou une pathologie associée, en administrant lesdites formulations liquides.<i />
Patent CA-2972742-A1 (CA)
Title: Processing contaminated water containing volatile compounds via flash evaporation
Inventor: ELGAT ZVI
IPC: F22G5/20
Filed: 2016-01-11
Abstract: Processing contaminated water containing volatile or/and semi-volatile compounds via flash evaporation. Method and system include: superheating contaminated water (via a superheating unit), for forming superheated contaminated water having a temperature equal to or higher than a predetermined threshold temperature; flash evaporating the superheated contaminated water (via a flash evaporation unit), for forming superheated contaminated steam; and thermally oxidizing the superheated contaminated steam (via a thermal oxidation unit), so as to thermally oxidize the volatile compounds contained therein, and form thermal oxidation gas/vapor products. Optionally, further includes integrated configuration and operation of a process control / data-information processing unit, and a heat recycling unit. Results in obtaining high yields and high energy efficiencies for removal of volatile compounds from contaminated water. Particularly applicable for processing water contaminated with volatile organic compounds (VOCs) or/and semi-volatile organic compounds (SVOCs), and volatile or/and semi-volatile inorganic compounds.
Patent CA-2975623-A1 (CA)
Inventor: REICHERT PAUL
IPC: A61K39/00
Filed: 2016-02-22
Abstract: La présente invention concerne des cristaux de pembrolizumab et d'anticorps monoclonaux anti-PD-l structuralement similaires, ainsi que des procédés de production de tels cristaux, et des utilisations de compositions comprenant de tels cristaux d'anticorps, par exemple dans le traitement de cancers. La présente invention satisfait à ces besoins et d'autres par fourniture de cristaux de pembrolizumab et un procédé de production de cristaux de pembrolizumab. Un mode de réalisation du procédé de l'invention produit des cristaux adaptés pour une diffraction des rayons X, et les inventeurs ont utilisé de tels cristaux pour résoudre la structure tridimensionnelle du pembrolizumab à une résolution de 2,3 A.
Patent CA-2976119-A1 (CA)
Inventor: MASSOT MAX
IPC: B64D33/04
Filed: 2016-02-03
Abstract: The invention relates to a flame-holder device (100) for the reheat channel of a turbojet comprising a chute-shaped arm (120) defining a cavity (121) and a heat shield (130) secured in the cavity of the arm. The flame-holder device (100) further comprises an attachment plate (110) comprising a first mast (114) integrally formed with the attachment plate (110) and a second mast (115) removably mounted on said plate, the arm (120) being attached to the first and second masts (114, 115) by attachment members.
Patent CA-2977694-A1 (CA)
Title: Programmable locking cylinder
Inventor: SERAFINI RENATO
IPC: E05B27/00
Filed: 2016-03-09
Abstract: The locking cylinder has a stator and a rotor, which can rotate in the stator and has a key opening into which a key can be inserted. The locking cylinder has a multiplicity of tumbler - mating-tumbler pairs, wherein each of the tumblers has a first part and a second part that are connected to one another, for example, with a press fit. In the method for programming a locking cylinder, the locking cylinder has at least one two-part tumbler, having parts that are connected to one another with a press fit. In the method, when a key is introduced into the key opening a length, effective in terms of locking, of the tumbler is changed by the first part and the second part sliding one into the other or moving apart from one another, in particular is reduced by them sliding one into the other.
Patent CA-2979868-A1 (CA)
Inventor: PAULUS NICOLAS
IPC: F16K31/02
Filed: 2017-09-22
Abstract: A proportional electromagnetic actuator includes: a magnetic casing; an electromagnetic plunger movable relative to the casing and having a first axial half;  a first radial gap and a second radial gap which are each formed radially between the plunger and the casing, and which are positioned axially at the first axial half of the plunger. These gaps are formed by concentric annular chamfers. A three-way valve for turbojet oil may be actuated by an electromagnetic actuator with double chamfered gaps.
Patent CA-2980584-A1 (CA)
Inventor: GINGERA GREGORY R
IPC: A01H5/10
Filed: 2017-09-28
Abstract: The present invention relates to a new and distinctive canola, designated G6667223H. Also included are seeds of canola G6667223H, to the plants, or plant parts, of canola G6667223H and to methods for producing a canola plant produced by crossing the canola G6667223H with itself or another canola genotype, and the creation of variants by mutagenesis or transformation of canola G6667223H.
Patent CA-2981574-A1 (CA)
Inventor: SUMITA OSAO
IPC: G21C7/28
Filed: 2016-01-25
Abstract: La présente invention concerne un système de faible encombrement de génération d'énergie nucléaire qui permet un réglage aisé du suivi de charge, est sans danger, et permet d'obtenir des réductions de coûts de production et de coûts d'entretien et de gestion. Le système de faible encombrement de génération d'énergie nucléaire est pourvu d'un petit réacteur qui adopte un réglage du suivi de charge et qui comprend : un coeur comprenant les assemblages combustibles (4) qui utilise un combustible métallique contenant soit de l'uranium (235, 238), soit du plutonium 239 ou les deux; une cuve de réacteur (1) qui renferme le coeur comprenant les assemblages combustibles (4); du sodium métallique chargé dans la cuve de réacteur (1) et chauffé par le coeur comprenant les assemblages combustibles; et un réflecteur de neutrons (2) qui maintient le facteur de multiplication effectif de neutrons émis par le coeur comprenant les assemblages combustibles (4) à approximativement un ou plus pour amener le coeur à un état critique, un élément métallique en forme de ressort ou de spirale est accouplé au réflecteur de neutrons, et la déformation thermique de l'élément métallique due à la température de sodium métallique caloporteur est utilisée pour commander le rendement de réflexion de neutrons rapides du réflecteur de neutrons afin de pouvoir maîtriser le facteur de multiplication effectif des neutrons.
Patent CA-2985625-A1 (CA)
Inventor: SEN ABHIK
IPC: G01N33/53
Filed: 2016-05-11
Abstract: The present disclosure provides for methods of treating a neurodegenerative condition, as well as methods for assessing the risk of developing a neurodegenerative condition, and assessing treatment efficacy in subjects who are carriers of the ApoE4 allele. Also disclosed is a method for diagnosing a neurodegenerative disorder.
Patent CA-2985943-A1 (CA)
Inventor: GEORGE KEVIN R
IPC: E21B33/08
Filed: 2017-11-17
Abstract: An efficient wiper plug seal integrity system and method for deviated/horizontal wellbore is disclosed. The system/method includes a wellbore casing installed into a wellbore along with restriction elements, a secondary engagement sub, a float collar and a shoe. A wiper plug is deployed into the wellbore casing after cement slurry is pumped into the wellbore casing. The secondary engagement sub provides a tapered entry guide directly above the float collar. The entry guide has a reduced inside diameter that serves to enhance the sealing integrity of the wiper plug and also aligns the wiper plug to properly latch into a locked position. In another system, a stepped diameter wiper plug with a reduced nose is disclosed. The reduced nose provides for an improved seal integrity that fits and latches into a smaller internal diameter secondary engagement sub.
Patent CA-2986784-A1 (CA)
Title: Yeast propagation simultaneous with saccharification
Inventor: GHISONI FLORA
IPC: C12P19/00
Filed: 2016-05-26
Abstract: The invention relates to a method for propagating yeast, for use in the production of a fermentation product from lignocellulosic biomass, including the steps that consist of: a. providing a reactor; b. placing in contact in said reactor: a population of yeasts capable of metabolising pentoses and hexoses, with 0.2 to 2.0 g of yeast solids per kg of prepared complete medium, raw marc from the pretreatment of the lignocellulosic biomass, with a solids content (MS) of 8 % to 15 %, nutrients, and cellulases, with 5 to 15 mg of proteins per gram of MS; and c. incubating the mixture at a temperature of 25 ºC to 38 °C, preferably 28 ºC to 33 °C, in microaerobiosis, in which the saccharification of the raw marc and the growth of the yeast are carried out simultaneously.
Patent CA-2987195-A1 (CA)
Inventor: LANDA BENZION
IPC: B41M3/00
Filed: 2016-05-27
Abstract: L'invention concerne une construction imprimée qui comprend : (a) un substrat d'impression qui possède une surface de réception d'image ; (b) une couche de réception, qui recouvre au moins partiellement ladite surface de réception d'image, et qui possède une surface de réception de particules disposée distalement par rapport à ladite surface de réception d'image, ladite couche de réception ayant facultativement une épaisseur d'au moins 1 000 nanomètres (nm) ; et (c) une pluralité de particules individuelles qui collent à ladite surface de réception de particules, et qui forment une monocouche sur cette dernière, dont les caractéristiques sont décrites ici.
Patent CA-2988263-A1 (CA)
Inventor: STRAMSKI DARIUSZ
IPC: B82Y20/00
Filed: 2015-06-03
Abstract: The subject matter disclosed herein provides methods for detecting and analyzing individual nanoparticles of the same, similar, or different sizes co-existing in a fluid sample using multi-spectral analysis. A plurality of light sources may be configured to produce a plurality of light beams at different spectral wavebands. An optical assembly may be configured to combine the plurality of light beams into one or more incident light sheets. Each incident light sheet may illuminate one or more nanoparticles in a liquid sample. One or more image detectors may be configured to detect, using a plurality of wavelengths, light scattered or emitted by one or more nanoparticles. The plurality of wavelengths may correspond to the different spectral wavebands of the plurality of light beams. Related apparatus, systems, techniques, and articles are also described.
Patent CA-2988798-A1 (CA)
Inventor: COVAS DIMAS TADEU
IPC: C07K14/745
Filed: 2016-04-27
Abstract: The present invention relates to a method for producing blood coagulation factor VII in 3 human cell lines (HepG2, Sk-Hep, HKB-11) and selecting the best recombinant protein producer. The murine BHK-21 cell line was used as the control. On the basis of the available data, it can be stated that the system used for modifying cell lines was effective, in that all cells were satisfactorily modified and produced the protein of interest in a stable form. Moreover, when the murine BHK-21 cell line is compared with human cells (HepG2, Sk-Hep-1 and HKB-11), the latter were capable of producing rFVII more effectively, and therefore the conclusion may be drawn that human cell lines are excellent alternatives for producing recombinant blood coagulation factors.
Patent CA-2988831-A1 (CA)
Inventor: ROTHE CHRISTINE
IPC: C12P21/02
Filed: 2016-07-15
Abstract: La présente invention concerne des mutéines de lipocaline lacrymale humaine qui se lient spécifiquement à LAG-3 et qui peuvent être utilisées dans des applications pharmaceutiques, par exemple en tant qu'agents anticancéreux et/ou modulateurs immunitaires pour le traitement ou la prévention de maladies humaines telles que le cancer, les maladies infectieuses et les maladies auto-immunes. La présente invention montre également que des mutéines de lipocaline humaine peuvent inhiber la liaison de LAG-3 au CMH de classe II sur des cellules surexprimant le CMH de classe II. La présente invention concerne également des procédés de production desdites mutéines de lipocaline se liant à LAG-3, ainsi que des compositions comprenant lesdites mutéines de lipocaline. L'invention concerne également des molécules d'acide nucléique codant pour lesdites mutéines de lipocaline et des procédés de production desdites mutéines de lipocaline et desdites molécules d'acide nucléique. De plus, l'invention concerne des utilisations thérapeutiques et/ou diagnostiques de ces mutéines de lipocaline, ainsi que des compositions comprenant une ou plusieurs de ces mutéines de lipocaline.
Patent CA-2989132-A1 (CA)
Inventor: SKAAKSRUD OLE-PETTER
IPC: H04W40/00
Filed: 2016-05-31
Abstract: Systems, apparatus, and methods are described for enhanced monitoring for an event candidate within a wireless node network. Such a system, for example, may include a server at a top level within the wireless node network, an ID node disposed at a low level within the wireless node network, and a master node disposed at a middle level within the wireless node network. The master node, which separately communicates with the server and the ID node and executes event detection code stored on its memory storage, is operative to detect a first and a second advertising signal broadcast by the ID node over a communication path with the ID node, compare an observed parameter of each of the first and second advertising signal (such as signal strength), identify the event candidate based upon the comparison, and use a second communication path to report the identified event candidate to the server.
Patent CA-2993893-A1 (CA)
Inventor: AISSAOUI HAMED
IPC: A61P37/00
Filed: 2016-09-14
Abstract: The invention relates to a crystalline form of (S)-2-(8-((5-chloropyrimidin-2-yl)(methyl)amino)- 2-fluoro-6,7,8,9-tetrahydro-5H-pyrido[3,2-b]indol-5-yl)acetic acid, processes for the preparation thereof, pharmaceutical compositions comprising said crystalline forms, pharmaceutical compositions prepared from such crystalline forms, and their use as a medicament, especially as CRTH2 receptor modulators.
Patent CA-2995121-A1 (CA)
Title: Detecteurs de flamme et procedes d'essai
Inventor: HUSEYNOV JAVID
IPC: G08B29/04
Filed: 2016-08-30
Abstract: La présente invention concerne, dans des modes de réalisation donnés à titre d'exemple, un détecteur de flamme et un procédé de fonctionnement. L'énergie optique est reçue au niveau d'un ou de plusieurs capteurs optiques et le détecteur traite l'énergie afin de déterminer si l'énergie reçue provient d'une source d'essai à distance connue. Si tel est le cas, le détecteur de flamme est actionné dans un mode d'essai. Si le traitement indique que l'énergie optique reçue n'est pas un signal d'essai, le détecteur de flamme est actionné dans un mode de fonctionnement de détection de flamme. Dans un mode de réalisation donné à titre d'exemple, le traitement du détecteur utilise un réseau neuronal artificiel dans le mode de fonctionnement de détection de flamme.
Patent CA-2996681-A1 (CA)
Inventor: PALMER BRIAN DESMOND
IPC: A61P25/00
Filed: 2016-08-25
Abstract: L'invention concerne des compositions pharmaceutiques comprenant des composés 3-amino-isoxazolopyridines de formule I ayant une activité inhibitrice d'IDO1 et/ou de TDO, dans laquelle W représente CR1, N ou N-oxyde; X représente CR2, N ou N-oxyde; Y représente CR3, N ou N-oxyde; Z représente CR4, N ou N-oxyde; et W, X, Y et/ou Z représentent N ou N-oxyde; et R9 et R10 sont tels que définis. L'invention concerne également des méthodes d'utilisation de tels composés dans le traitement de diverses affections, telles que le cancer.
Patent CA-2997329-A1 (CA)
Title: Mounting element for mounting an architectural covering between opposing mounting surfaces
Inventor: BOHLEN J
IPC: E06B9/42
Filed: 2018-03-05
Abstract: A mounting element, for mounting an architectural covering between two opposing mounting surfaces, comprising: -    an elongate mounting member, -    an extension mechanism (104) operable between: i) a retracted state, and ii) an extended state in which the mounting element can be fastened to the architectural recess, -    an actuator (110) rotatable about a rotation axis (Y110) which is not parallel to the longitudinal direction, and a conversion mechanism (112) to convert a rotation of the actuator (110) into a translatory movement of the rotation axis (Y110) along the longitudinal direction (X102) and vice versa. The extension mechanism (104) is arranged to abut one of the opposing mounting surfaces (302) in the extended state when the mounting element is mounted between the opposing mounting surfaces (302).
Patent CA-2998338-A1 (CA)
Inventor: WARREN WESLEY JOHN
IPC: E21B43/22
Filed: 2015-12-22
Abstract: La présente invention concerne, selon des modes de réalisation, des systèmes et des procédés permettant de déterminer la quantité de matériau en vrac alimentée par étranglement dans une entrée d'un mélangeur à partir d'un ou de plusieurs contenants de matériau en vrac placés sur une structure de support. Le système comprend des capteurs placés sur la structure de support au-dessous du ou des contenants afin de déterminer la quantité de matériau en vrac se trouvant dans le contenant à n'importe quel moment. En surveillant le changement de masse du matériau dans les contenants au fil du temps, il est possible de déterminer la quantité de matériau alimentée dans le mélangeur. Le matériau est dosé dans un mixeur situé dans le mélangeur, grâce à un mécanisme de dosage tel qu'une vis à sable qui fournit une capacité fixe de matériau en vrac dans le mélangeur. La capacité à mesurer précisément la quantité de matériau en vrac alimentée par étranglement dans le mélangeur permet à des opérateurs d'étalonner la vis à sable de façon continue.
Patent CA-2999435-A1 (CA)
Inventor: DANTER WAYNE
IPC: A61K31/513
Filed: 2011-04-01
Abstract: The invention relates to a compound of Formulae I and/or II: Formula I Formula II  and/or a pharmaceutically-acceptable salt, hydrate, solvate, tautomer, optical isomer, E-isomer, Z-isomer, or combination thereof; X is selected from Se, N-OH, NH, NO2, CN, N-CN, N=O, O or S, and the remaining substituents are described herein; and a composition thereof. The invention also relates to a method of administration thereof; and use thereof to treat HIV.
Patent CA-3002855-A1 (CA)
Inventor: EBERSPACH GUNTER
IPC: B60H1/02
Filed: 2018-04-24
Abstract: The vehicle temperature control system, especially adapted for use in a hybrid vehicle, makes possible an improved use of the thermal energy provided in a vehicle.  The present vehicle temperature control system includes first (12) and second (14) heat transfer medium circuits. The first heat transfer medium circuit (12) includes a heater (18) having a heater heat exchange unit (22) and a first heat transfer medium circuit valve array (28) for releasing/blocking the internal combustion engine (16) for/against the flow of the first heat transfer medium. The first heat transfer medium can flow through at least one of the heat transfer medium circuit heat exchanger unit (58) and the heater heat exchanger unit (22) of the heater (18) regardless of a switching position of the first heat transfer medium circuit valve array (28).