baber/WOPTO huggingface dataset:
Patent CA-2449680-A1 (CA)
Inventor: NEUMANN THOMAS
IPC: C07K1/12
Filed: 2002-06-07
Abstract: Provided is a method for characterising a polypeptide, which method comprises the steps of: (a) optionnally reducing cysteine disulphide bridges in the polypeptide to form free thiols, and capping the free thiols; (b) cleaving the polypeptide with a sequence specific cleavage reagent to form peptide fragments; (c) optionally deactivating the cleavage reagent; (d) capping one or more .epsilon.-amino groups that are present with a lysine reactive agent;  (e) analysing peptide fragments by mass spectrometry to form a mass fingerprint for the polypeptide; and (f) determining the identity of the polypeptide from the mass fingerprint.
Patent CA-2451483-A1 (CA)
Inventor: KOPRESKI MICHAEL S
IPC: C12Q1/6886
Filed: 2002-06-24
Abstract: This invention provides methods for detecting or inferring the presence of malignant or premalignant cells in a human wherein the malignant or premalignant cells express COX-2. The methods of the invention detect extracellular COX-2 RNA in blood, plasma, serum, and other bodily fluids. Th e inventive methods are useful for aiding detection, diagnosis, monitoring, treatment, or evaluation of neoplastic disease, and for identifying individuals for whom COX-2 directed therapies would be beneficial.
Patent CA-2452051-A1 (CA)
Title: Computer-assisted reconciliation of multiple image reads
Inventor: SABOL JOHN M
IPC: G16H30/20
Filed: 2003-12-04
Abstract: A technique for reconciling two or more reads of an image data set (52). One or more computer implemented routines is employed to provide computer-assisted reconciliation (CAR) including resolution of discrepancies (86) between the two or more reads. The computer-assisted reconciliation may optimally display the discrepancies (86), the concurrences (84) and any associated information to a human reconciler, may resolve the discrepancies in a partially automated manner, or may resolve the discrepancies in a fully automated manner. The reconciled data (94) may then be provided to an end user.
Patent CA-2452743-A1 (CA)
Title: 5-arylsulfonyl indoles having 5-ht6 receptor affinity
Inventor: FU JIAN-MIN
IPC: A61P25/28
Filed: 2002-08-01
Abstract: The invention provides derivatives of 5-arylsulfonyl indole and 5-arylsulfonyl indoline compounds which may be in the form of pharmaceutical acceptable salts or compositions that are useful in treating central nervous system diseases such as anxiety and depression. The invention also includes intermediates and processes to make the compounds, isotopically-labeled forms of the compounds and the use of the isotopically labeled forms of the compounds to perform nuclear magnetic resonance imaging and positron emission tomography.
Patent CA-2454742-A1 (CA)
Inventor: LARKING STUART
IPC: G06F40/143
Filed: 2002-07-26
Abstract: The system includes a novel software application (82) operative to use the modeling language to create, read and modify interactive representation models of the proposed applications, a memory (86) to store requirement data and interactive representation model data, a software application (92) operative to read and update the interactive representation model data across a computer network, a software application (76) operative to maintain a record of the requirements and to administer operation of the system, a software application (78) operative to render interactive representations of the proposed applications in browser readable format, a software application (82) operative to allow multiple instances of other applications to access interact representation data and requirement data residing in the memory and a software application (84) operative to allow an individual user's interactions with the system to be broadcast across a networked system to other users.
Patent CA-2454995-A1 (CA)
Inventor: BURTON DAVID
IPC: B23P19/04
Filed: 2004-01-07
Abstract: A method and apparatus for assembling a fluid conduit assembly and testing the fluid conduit for leaks. Clipping devices support fasteners at a position remote from the conduit. According to the invention the fasteners can be loaded into clip nests provided by the clipping devices while leak testing of the conduit is performed. The performance of these steps simultaneously effectively eliminates the conventional requirement of pre-loading installation fasteners into the leak testing apparatus, and thus reduces the overall time required for the testing and assembly of fluid conduits by approximately one third. If the leak test is successful, all of the fasteners are then moved to the conduits and closed to integrate the conduit assembly.
Patent CA-2455451-A1 (CA)
Title: Diagnostic imaging tabletop
Inventor: LONGTON WALLACE A
IPC: A61B19/00
Filed: 2002-07-09
Abstract: A tabletop (30) useful for accurate positioning of a patient for imaging and diagnosis, so that patient positioning in subsequent medical treatments, suc h as radiation therapy, accurately and precisely correlates with the imaging data. The tabletop (30) of the present invention is a solid flat tabletop (3 1) adapted to fit over or as an insert in a conventional CT imaging or imaging scan table and provides a flexible support section (32) in which the flexibl e support material (33) is tensioned to provide a vertical deflection corresponding to the vertical deflection of a flexible patient support of a treatment simulator or linear accelerator. In a preferred embodiment, the flexible support section (33) may be removed and inserted into the treatment table (30) to provide an exact correlation in vertical deflection during treatment.
Patent CA-2458806-A1 (CA)
Title: Antisense oligonucleotide against human ache and uses thereof
Inventor: SOREQ HERMONA
IPC: A61K31/7088
Filed: 2002-05-23
Abstract: The invention relates to an antisense oligonucleotide targeted to the coding region of the human acetylcholinesterase (AChE), which selectively suppresses the AChE-R isoform of the enzyme. The antisense oligonucleotide is intended for use in the treatment and/or prevention of neuromuscular disorders, preferably myasthenia gravis. In addition, it can penetrate the blood-brain barrier (BBB) and destroy AChE-R within central nervous system neurons, while also serving as a carrier to transport molecules across the BBB.
Patent CA-2461010-A1 (CA)
Title: Procede de synthese de polynucleotide par traduction inverse a partir d'une proteine, et oligonucleotide utilise dans ce procede
Inventor: NASHIMOTO MASAYUKI
IPC: C12N15/11
Filed: 2002-03-20
Abstract: L'invention concerne un matériau moléculaire destiné à la synthèse d'un polynucléotide par traduction inverse, à partir d'une protéine codée par le nucléotide, ce matériau, un oligonucléotide assurant la médiation de traduction inverse, étant caractérisé par le fait (a) qu'il contient une séquence nucléotidique nnn codant pour des résidus acides aminés Xaa, (b) que cette séquence nnn n'est pas séparable, c) qu'il contient une séquence nucléotidique qui se lie aux résidus acides aminés Xaa, et (d) qu'il ne contient aucune autre séquence nucléotidique qui se lierait à des résidus acides aminés autres que Xaa. L'invention concerne aussi un procédé de synthèse d'un polynucléotide qui code pour la séquence d'acides aminés d'une protéine matrice par une réaction de traduction inverse au moyen de l'oligonucléotide décrit.
Patent CA-2461502-A1 (CA)
Inventor: MICEK LAWRENCE L
IPC: E01H5/09
Filed: 2004-03-19
Abstract: A snow removal machine including a housing with a forward opening through which snow enters the snow removal machine. At least one rotatable member is positioned and rotatably secured within the housing for engaging and eliminating the snow from within said housing. The snow removal machine also includes a surface treatment application system with a treatment material dispensing system connected to the housing for dispensing a liquid or solid deicer and/or anti-icing treatment material over an area from which snow has been removed.
Patent CA-2462186-A1 (CA)
Inventor: WIEDEMANN RALF
IPC: B65B9/04
Filed: 2002-09-23
Abstract: Process for producing a sealed water-soluble package of improved aesthetic appearance by treating at least part of the outer surfaces of the sealed package with a plasticizer composition and applying heat thereto, a package obtainable thereby and a specified use of such package.
Patent CA-2465016-A1 (CA)
Title: Packaging for grouped similar items, including elongated items such as drill bits and the like
Inventor: YERKES ROBERT
IPC: B25H3/00
Filed: 2004-04-19
Abstract: A package for like articles, especially elongated articles, such as drill bits and the like, is provided with a plurality of compartments or sectioned off regions, for the containment of an individual article for substantially unfettered visual inspection; for the containment of a further plurality of articles identical to the exposed visual article, and for indicia as required by the manufacturer and/or required by law. The package is configured to be presented in a hanging manner from retail display shelving.
Patent CA-2467185-A1 (CA)
Inventor: DONG JANE
IPC: B65D51/18
Filed: 2004-05-13
Abstract: In an illustrative embodiment, a container to store a plurality of articles comprises a body and a cover. the cover is adapted to close the body and comprises at least one opening and at least one lid to close the opening. The lid has a first end and a second end. The first end of the lid may be pivotally connected to the cover. The lid may be slidably connected to the cover. The lid is capable of being in an opened position and in a closed position. The container may comprise a second cover adapted to fit into a cavity in the cover with the opening and the lid located in the cavity. The second cover may completely cover the cavity. The second cover may completely cove the opening and the lid. An outer rim and a tear strip at the bottom of the outer rim for the opening the cover may be provided. The opening is adapted to receive a human hand when the lid is in the opened position to retrieve articles. The lid may be a rectangle, triangle, or a semicircle, for example. The lid may comprise a snapper on the second end of the lid to close the lid. The cover may be removable from the body. The lid and the opening may be fully within the cover. The pivotal connection may comprise a hinge, for example.  The articles may comprise at least on form the following list of fasteners: nuts, screws, and bolts, for example.
Patent CA-2470708-A1 (CA)
Title: Foldable barbecue grill
Inventor: CHUNG KIOSKY
IPC: A47J37/07
Filed: 2004-06-11
Abstract: A barbecue grill includes a frame, two support racks pivotally mounted on two ends of the frame, and a stretcher detachably mounted on the frame and urged between the two support racks to support the two support racks at an upright state by restriction of the stretcher. Thus, the two support racks of the barbecue grill are folded when not in use so as to save the space of storage. In addition, the barbecue grill is expanded and partially folded easily and conveniently, thereby facilitating a user operating the barbecue grill.
Patent CA-2471465-A1 (CA)
Title: Novel g-protein coupled receptors
Inventor: POWERS SCOTT
IPC: C12N15/12
Filed: 2002-12-18
Abstract: The invention provides isolated nucleic acid and amino acid sequences of fou r novel G-protein coupled receptors that are amplified in breast cancer cells, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of G-protein coupled receptors.
Patent CA-2473093-A1 (CA)
Title: Transfer and insulation device for electrolysis
Inventor: KIVISTO TUOMO
IPC: C25C7/06
Filed: 2003-03-20
Abstract: The invention relates to a transfer and insulation device (1) for electrically insulating electrodes, particularly anodes (2) and cathodes (3), used in the electrolytic cleaning of metals, from each other in an electrolytic tank (4), for distributing the electrodes as they are hanging in the electrolytic tank and for enabling the electrodes to be transferred, said transfer and insulation device (1) being made of one single piece.
Patent CA-2473490-A1 (CA)
Inventor: MANDEL ARKADY
IPC: A61K47/48
Filed: 2003-01-21
Abstract: A composition of matter capable of producing an anti-inflammatory response in vivo in a mammal comprises bodies having a three-dimensional core structure of conformation and size from about 20nm to about 500 m and expressing or expressible on the surface thereof RGDS ligands which will react, optionally in the presence of adapter molecules, with at least one specific receptor wherein the binding of said ligand with said receptors produces an anti-inflammatory response in vivo in said mammal.
Patent CA-2473494-A1 (CA)
Inventor: ICHINOSE TADAHARU
IPC: G01F1/42
Filed: 2003-02-06
Abstract: A flow regulating valve (11), which has a valve disk (11b) operably disposed in a flow channel and is capable of regulating the flow of fluid according to the valve opening degree of the valve disk (11b), is characterized by comprising a stress detecting means (13) for detecting the flow-channel- direction force component of a load applied to the valve disk by the fluid, and a valve opening degree detecting means (12) for detecting the degree of opening of the valve disk. The flow rate calculating means (14) finds the flow rate (Qm) from the stress (fm) obtained from the stress detecting means and from the valve opening degree (.theta.m) obtained from the valve opening degree detecting means. A control means (15) controls a valve disk driving means (18) on the basis of the flow rate to drive the valve disk for opening and closing. This makes it possible to find the flow rate with higher sensitivity and accuracy than in the prior art, the construction being compact and simple, providing stabilized data.
Patent CA-2475216-A1 (CA)
Title: Method and system for providing third party authentification of authorization
Inventor: GEETHA MANGALORE
IPC: G06F21/31
Filed: 2003-01-02
Abstract: A method and system (100) for providing third party authentication when requesting content and/or services from an application server (106). The method is applicable to key management protocols that utilize the concept of tickets. The method and system include a client (102) being coupled with a third party application server (107), wherein the client submits a request f or content from the third party application server and the third party application server returns requested information and corresponding authentication. The client further couples with a first application server (106), wherein the client submits a key request (KEY_REQ) including the thir d party server information and corresponding authentication to the first application server. The first application server authenticates the third par ty server information and verifies client authorization based on third party information. The first application server returns a key reply (KEY_REP) if t he third party server information is authenticated and client authorization is verified.
Patent CA-2475925-A1 (CA)
Inventor: KREUZER BERND
IPC: B62D65/00
Filed: 2002-02-20
Abstract: L'invention concerne un dispositif (10) servant ~ traiter des pi­ces ~ usiner, notamment des caisses de v~hicules (22), et ayant une structure modulaire. Le dispositif selon l'invention comporte un premier module qui comprend une ligne de traitement (12), une ou plusieurs zones de traitement (14) pour le traitement de surface des pi­ces ~ usiner (22), ainsi qu'un dispositif de guidage (44) le long de la ligne de traitement. Le dispositif selon l'invention comporte ~galement un deuxi­me module qui comprend un ou plusieurs ch~ssis (20b) auxquels les pi­ces ~ usiner (22) peuvent Útre fix~es et qui peuvent se d~placer le long du dispositif de guidage (44). Il est possible de combiner diff~rents types de deuxi­mes modules au premier module afin d'obtenir des configurations diff~rentes du dispositif entier en ce qui concerne le d~bit et la souplesse.
Patent CA-2478401-A1 (CA)
Title: Treatment of surfaces populated by bacteria
Inventor: PRITCHARD DAVID IDRIS
IPC: A01N63/14
Filed: 2003-03-06
Abstract: A surface populated by a bacteria capable of producing a biofilm is treated beneficially by contacting it with a substance having N-acyl homoserine lactone degradant activity obtained from the secretions and/or excretions of the larval form of the green bottle fly, Lucilia sericata. Furthermore, a synergistic effect is achieved when the larval secretions/excretions are use d in combination with an antibiotic, e.g. tetracycline. Such a substance havin g N-acyl homoserine lactone degradant activity obtained from Lucilia sericata larval secretions and/or excretions also forms part of the invention.</SDOAB >
Patent CA-2478729-A1 (CA)
Title: Improved duct bleed leak detection system
Inventor: FERNANDES LESLIE
IPC: G01M3/28
Filed: 2004-08-24
Abstract: A leak detector for an insulated duct carrying pressurized hot air comprises a cuff secured over a circumferential cut in the insulation of the duct, thereby creating a reservoir of hot air which has leaked from the duct, a manifold defining a conduit therein in communication with the hot air reservoir and a cap for securing heat sensitive wires to manifold at the end of the conduit such that the hot air from the hot air reservoir impinges directly on the heat sensitive wires
Patent CA-2478944-A1 (CA)
Title: Full scale video with overlaid graphical user interface and scaled image
Inventor: SLOO DAVID HENDLER
IPC: H04N7/16
Filed: 2004-08-24
Abstract: The present disclosure relates to displaying full scale images with overlaid similar scaled images and a graphical user device in a display of a client device.   The client device receives video streams of the full scale images and scaled images. The video streams are broadcast independent of one another, and a user of the client device may manipulate the format of the images of either or both streams, and/or place the scaled image on any portion of the full scaled image. The graphical user interface is placed so it does not obscure the scaled image. Alternatively a single video stream may be received by the client device. When a single video stream is received, the client device creates two video streams, one stream comprising full scale images and the other stream comprising scaled images. The full scale image is overlaid with the scaled image and the graphical user interface.
Patent CA-2479532-A1 (CA)
Inventor: AUBIN RANDY R
IPC: A01K5/01
Filed: 2004-09-22
Abstract: The livestock feeding device comprises two feed gates appropriately attached to a main frame such that the base of the feed gates does not contact the ground. The feed gates, in combination with the end frames contain the forage within the feeder. The feed gates are appropriately designed such that the animal can pass its mouth and or head through the feed gate but not its shoulders. Suspension rods connect the feed gate to the articulation brackets. The articulation brackets are angled such that when attached the feed gates swing against, and remain in contact with, the surface of the baled forage during feeding, and the bottom corners of the feed gates touch when empty. The feed gate shape will match the shape of the baled forage. The feed gates swing upwards for loading. The device essentially eliminates freeze-down and provides a labour-free low wastage feeder primarily for short- necked livestock.
Patent CA-2480800-A1 (CA)
Title: Inhibitors of akt activity
Inventor: HARTNETT JOHN C
IPC: C07D333/56
Filed: 2003-04-04
Abstract: The present invention is directed to compounds comprising a 2,3-diphenylquinoxaline moiety which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention.
Patent CA-2481758-A1 (CA)
Title: Electrical evaporator with adjustable evaporation intensity
Inventor: MARCHETTI FABIO
IPC: A01M1/20
Filed: 2003-04-07
Abstract: An evaporator includes a housing, a bottle containing a substance to be evaporated, a wick having a lower portion disposed within the bottle and an upper portion protruding from the bottle, a heating device disposed within the housing at a position proximate to the upper portion of the wick, and an adjustment mechanism within the housing for displacing at least the upper portion of the wick toward or away from the heating device in a direction substantially perpendicular to the longitudinal axis of the wick. In a preferred embodiment, the adjustment mechanism includes a hollow cylindrical portion that engages the upper portion of the wick, and a dial portion for rotating the hollow cylindrical portion about an axis of rotation.
Patent CA-2485253-A1 (CA)
Inventor: BUDZYNSKI WLADYSLAW
IPC: A61P35/00
Filed: 2003-05-09
Abstract: La structure de base du pentaérythritol est utilisée pour remplacer l'un des sucres ou les deux sucres du lipide A, ce qui donne lieu à la génération d'une série d'analogues du lipide A. Lesdits analogues du lipide A peuvent se distinguer du lipide A également en ce qui concerne, par exemple, le nombre, la nature et l'emplacement de groupes à charge négative, et le nombre, la nature et l'emplacement des chaînes lipidiques. Les analogues du lipide A peuvent être des agonistes du lipide A, utiles en tant qu'immunostimulateurs, ou des antagonistes du lipide A, utiles pour le traitement d'un choc infectieux. De la même manière, un résidu de pentaérythritylamine peut être utilisé pour remplacer un résidu de sucre aminé dans un ligand glucidique présentant une activité biologique d'intérêt, ce qui a pour effet de générer une série d'analogues dudit ligand. Ces derniers peuvent servir, par exemple, d'haptènes, d'inhibiteurs de l'adhésion de cellules hôtes bactériennes, etc.
Patent CA-2485623-A1 (CA)
Title: Network, server apparatus, ip corresponding terminal device, and speech-quality control method used in the same
Inventor: TAKAI MINAKO
IPC: H04L12/66
Filed: 2004-10-20
Abstract: A network includes Internet protocol (IP) terminals for establishing communication using an initiation protocol used in connection-oriented communication in which connection to a destination is confirmed over an IP network for the communication; and a server apparatus constituting the network along with the IP terminals. The server apparatus includes a detecting unit for detecting a speech quality between the IP terminals; a calculating unit for calculating an optimal speech quality based on the detected speech quality information; and a notifying unit for notifying the IP terminals establishing communication of the calculated optimal speech quality. The IP terminals establish communication with the speech quality being set to the optimal speech quality, which the server apparatus notifies to the IP terminals.
Patent CA-2488335-A1 (CA)
Title: Sunscreen compositions
Inventor: SANOGUEIRA JAMES P
IPC: A61K8/81
Filed: 2003-06-04
Abstract: The present invention is directed to a cosmetic composition that has an amount of at least two rheology-modifying agents such that the viscosity of the composition remains stable over a broad temperature range. The compositions of the present invention may also include at least one of the following additional components: sunscreen agent, SPF booster, secondary emulsifier, emollient, moisturizer, humectant, film former/waterproofing agent, bio-active (functional) ingredient, pH adjuster/chelating agent, preservative, fragrance, effect pigment, color additive, or any combinations thereof.
Patent CA-2490579-A1 (CA)
Title: Methods for specifically inhibiting histone deacetylase-7 and 8
Inventor: LI ZUOMEI
IPC: C07D239/42
Filed: 2003-06-12
Abstract: This invention relates to the inhibition of histone deacetylase (HDAC) expression and enzymatic activity. The invention provides methods and reagen ts for inhibiting HDAC-7 and HDAC-8 by inhibiting expression at the nucleic aci d level or inhibiting enzymatic activity at the protein level.