baber/WOPTO huggingface dataset:
Patent CA-2588038-A1 (CA)
Inventor: PLUM LORI A
IPC: C07C401/00
Filed: 2005-11-18
Abstract: Compounds of Formula (I) are provided where X1 and X2 are independently selected from H or hydroxy protecting groups. Such compounds may be used in preparing pharmaceutical compositions and are useful in treating a variety of biological conditions.
Patent CA-2589527-A1 (CA)
Title: Pyridazinone compounds
Inventor: ZHOU YUEFEN
IPC: C07D417/14
Filed: 2005-12-16
Abstract: The invention is directed to pyridazinone compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
Patent CA-2590402-A1 (CA)
Title: Fiber optic mems seismic sensor with mass supported by hinged beams
Inventor: ZHOU TIANSHENG
IPC: B81B7/02
Filed: 2007-05-18
Abstract: The present invention relates to an optic seismic MEMS sensor. More specifically, a proof mass is supported by a frame having supporting beams.  The proof mass is positioned within the frame and has a hinged attachment to the beams.  The proof mass has a sensor gap having a first reflector and a second reflector positioned at opposing ends of the sensor gap. An optical fiber injects light into the sensor gap and light is reflected to determine seismic movement of the proof mass with respect to the frame. Stops are provided for limiting the movement of the proof mass to minimize strain on the attachment of the beams and the proof mass.
Patent CA-2590593-A1 (CA)
Inventor: ROY DENIS-CLAUDE
IPC: C07K16/18
Filed: 2007-06-01
Abstract: A polypeptide, the amino acid sequence of which comprises a sequence as set forth in Figure 15A (SEQ ID NO: *), including at least one mutation within the degron domain of the polypeptide encompassed between positions 1 and 35 of the sequence, wherein said at least one mutation reduces the susceptibility of the polypeptide to ubiquitin-proteasome degradation.
Patent CA-2592368-A1 (CA)
Inventor: FRAZELL DALE M
IPC: A46B5/02
Filed: 2007-06-18
Abstract: A cleaning brush with a dispenser for cleaning product is described. The cleaning product is stored in a cavity, and is dispensed by pressing on a flexible membrane on one side of the cavity. When thus depressed, the cleaning product is extruded through holes in the head into the region of the bases of bristles on the front side of the brush. The toothbrush is ergonomically shaped in a concave spoon like shape to fit a user's hand more comfortably. The brush may include a cover which has a general appearance of a fountain pen to facilitate an in obtrusive carrying of the brush.
Patent CA-2593165-A1 (CA)
Title: Analgesic conjugates
Inventor: ROERIG SANDRA C
IPC: C07D489/02
Filed: 2005-01-05
Abstract: The present invention relates generally to analgesic compounds having a mu opioid receptor agonist linked to a delta opioid receptor antagonist, and to methods for producing analgesia using such compounds. As compared to opioids such as morphine, these compounds can cause less tolerance, physical dependence, and/or constitpation. These compounds are also more potent than morphine and are able to cross the blood brain barrier, thereby allowing for peripheral (e.g., IV) administration.
Patent CA-2594349-A1 (CA)
Title: Methods and compositions for treating, inhibiting and reversing disorders of the intervertebral disc
Inventor: GEMBA TAKEFUMI
IPC: A61K48/00
Filed: 2006-01-11
Abstract: Described herein are methods and compositions for inhibiting, treating and reversing intervertebral disc disorders using transcription factor inhibitors. In certain embodiments, the transcription factor inhibitor targets the transcription factor NF-kappaB. Also described are methods and compositions where intervertebral disc disorder is reversed using a decoy oligodeoxy-nucleotide that blocks NF-kappaB.
Patent CA-2594841-A1 (CA)
Title: Method and geodetic device for surveying at least one target
Inventor: ROHNER MARCEL
IPC: G01C15/00
Filed: 2006-01-12
Abstract: The invention relates to a method for surveying at least one target (17) using a geodetic device (13). According to said method, a camera of the device (13) captures a visual image and surveys an angle and/or a distance to the target with geodetic precision, the angle and/or distance surveillance being supported or controlled by the visual image. At the same time of capture of the visual image at least two distance points of a distance image are captured as the spatial distribution of discrete distance points in the area of detection (14b). When the visual image and the distance image are correlated with each other, the target is recognized or the measuring process is controlled.
Patent CA-2595942-A1 (CA)
Title: Treatment of degenerative diseases with the x-linked inhibitor of apoptosis
Inventor: WARING JAMES
IPC: A61K35/407
Filed: 2006-01-30
Abstract: Methods and compositions comprising vectors expressing XIAP or XIAP protein preparations for the treatment of degenerative disorders including retinal degeneration, skeletal muscular atrophy, spmal muscular atrophy (SMA), spmobulbar muscular atrophy (SBMA), amyolateral sclerosis (ALS), muscular dystrophy, Parkinson's disease, cardiac injury, and liver disease, and for the reduction of cell apoptosis during transplantation of cells are provided.
Patent CA-2599149-A1 (CA)
Inventor: UEMIZO YOSHIAKI
IPC: G07D7/00
Filed: 2005-01-12
Abstract: A paper money discriminating device, comprising a carrying device (2) having a rotor (5) rotatably disposed in a case (1), a drive device (12) rotating the rotor (5), and a plurality of pressing rollers (11) disposed around the rotor (5) in the state of being brought into contact with the outer peripheral surface of the rotor (5). A paper money (10) inserted from an inlet (8) in the case (1) is held between the rotor (5) and the pressing rollers (11), wrapped around the outer periphery of the rotating rotor (5) over its full length, and securely carried while the paper money (10) is prevented from being slipped by the rotating motion of the carrying device (2). Also, since the paper money (10) is rotated one or more turns integrally with the rotor (5), the illicit extraction of the paper money (10) by an extractor can be prevented. When the physical properties of the paper money (10) are detected by a sensor (3) and a controller (4) determines that the paper money (10) is true, the paper money (10) is separated from the rotor (5) and discharged from an outlet (9).
Patent CA-2599465-A1 (CA)
Inventor: DINSMORE ANDREW JOHN
IPC: C07K16/46
Filed: 2006-02-17
Abstract: The present invention relates to novel rodent control agents comprising antibodies, or antigen-binding fragments thereof, that bind to proteins expressed in rodents and in particular antibodies or antigen-binding fragments that bind to proteins expressed in the gastrointestinal (GI) tract of rodents, as well as to methods of making such novel rodent control agents. The invention further extends to novel antibodies and antigen-binding fragments for use in rodent control as well as to methods of controlling rodents through the use of such antibodies, antigen binding fragments and novel rodent control agents.
Patent CA-2600673-A1 (CA)
Title: Adjustable trailer coupling system
Inventor: WEBER RICHARD
IPC: B60D1/36
Filed: 2004-03-11
Abstract: Towing adjustment and coupling techniques may include a retentive lateral trailer adjustment device of a trailer (1) configured to provide lateral adjustment of the trailer (1). In some embodiments, a trailer (1) may include a coupler element (3), and at least one retentive lateral adjusment device configured to provide adjustment in a lateral direction (8) of the coupler element (3). Embodiments may have configurations directed to couplers such as a gooseneck hitch, a fifthwheel hitch, and a pull-type or tongue hitch.  Embodiments may also provide a fore-aft position indicator (44) with or without a fore-aft position sensor (50) through which proper positioning of a source of tow power (54) relative to the trailer (1) may be facilitated in a fore-aft direction (7). Corresponding methods are included as embodiments of the invention.
Patent CA-2603199-A1 (CA)
Inventor: SANI MUSA
IPC: A61K39/40
Filed: 2007-10-12
Abstract: The present invention relates to compositions and methods for blocking entry of Shigella into a cell of an animal, to therefore providing protection against, or reduce the severity of Shigella infections. More particularly it relates to the use of the IpaD protein obtained from natural sources and/or through synthesis or recombinant technology, and conjugates thereof to induce neutralizing antibodies having protective activity against several serotypes of Shigella, in particular S.  flexneri. The composition of the invention is useful to prevent and/or treat shigellosis caused by a bacterium of the Shigella family.
Patent CA-2603235-A1 (CA)
Title: Diindolylmethane-based compositions and methods of use thereof for promoting oral mucosal and bone health
Inventor: ZELIGS MICHAEL A
IPC: A61K8/18
Filed: 2006-03-28
Abstract: The present invention includes compositions and methods for the treatment and prevention of oral mucosal disorders and for promotion of bone health. In particular, the present invention describes new therapeutic and preventative uses for 3,3'-diindolylmethane (DIM), or a DIM-related indole, alone or in combination with anti-inflammatory agents and/or antibacterial agents, to treat oral mucosal disorders and promote bone health. The compositions of the invention are used to prevent and reverse oral mucosal disorders and bone loss (osteopenia and osteoporosis) associated with aging and chronic inflammation.  Oral mucosal disorders include Periodontitis, gingivitis and related oral mucosal inflammation. Formulations of the compositions of the invention include capsules, tablets, toothpastes, oral gels, mouthwashes, mouth rinses, lozenges, chewing gum, dental floss, and dental topical formulations, and fortified foods.
Patent CA-2604562-A1 (CA)
Inventor: MAUGERI CATERINA
IPC: A61P29/00
Filed: 2006-05-03
Abstract: Use of a benzoyl derivative of 3-aminocarbazole to produce a drug for the preventive or therapeutic treatment of a disorder selected form the group comprising inflammatory processes, pain, fever, tumours, Alzheimer's disease and atherosclerosis. Method for the preventive or therapeutic treatment of a disorder selected from the group comprising inflammatory processes, pain, fever, tumours, Alzheimer's disease and atherosclerosis in which a therapeutically effective quantity of a benzoyl derivative of 3-aminocarbazole according to the invention is administered to an individual.
Patent CA-2608986-A1 (CA)
Inventor: OLIVER ROBERT ANDREW
IPC: B60K25/00
Filed: 2006-04-21
Abstract: A drive arrangement is disclosed for a motor vehicle power take off (PTO). The arrangement comprises a PTO shaft 104,158,207 of a known type intended for coupling to a power driven implement. An input shaft is arranged to be coupled to a rotary driver such as an engine. A continuously variable transmission such as 10 is coupled between the input and PTO shafts to transfer drive between them at a continuously variable ratio. In accordance with the invention, the continuously variable transmission is constructed and arranged such as to regulate torque and to automatically accommodate changes in speed at the PTO Shaft by virtue of changes in its drive ratio.
Patent CA-2609367-A1 (CA)
Inventor: KNAUF VIC C
IPC: A23L33/00
Filed: 2006-05-22
Abstract: La présente invention concerne des compositions et des procédés de préparation d'acide gamma-linolénique (AGL) dans des plants de safran, notamment dans des graines de safran. Des séquences d'acide nucléique et des constructions codant une ou plusieurs séquences de désaturase d'acide gras sont utilisées pour générer des plants de safran transgénique qui contiennent et expriment une ou plusieurs de ces séquences et produisent des taux élevés de AGL dans les graines de safran. Cette invention concerne des plants et des graines de safran transgénique qui produisent des taux élevés de AGL, des huiles produites à partir des graines selon l'invention, des méthodes de traitement de diverses maladies telles que les troubles du système nerveux, les états inflammatoires, le cancer et les troubles cardio-vasculaires au moyen des huiles selon l'invention.
Patent CA-2610166-A1 (CA)
Inventor: YOSHIZAKI HIDEO
IPC: A61P9/04
Filed: 2006-04-24
Abstract: Disclosed is a compound which has a highly selective inhibitory effect on Rho-kinase and is useful as a therapeutic agent for diseases including hypertension, pulmonary hypertension, cerebral vasospasm, angina pectoris, heart failure, arteriosclerosis, glaucoma, dysuria, asthma and erectile dysfunction. A homopiperazine derivative represented by the general formula (1), an acid-addition salt thereof or a solvate of the derivative or the salt:  wherein R1 represents an amino acid residue; R2 represents a hydrogen atom or an alkyl group; R3 represents a hydrogen atom, an alkyl group, an alkenyl group, an alkynyl group, an alkoxy group, a halogen atom, a nitrile group or a hydroxyl group; and R4 represents a hydrogen atom, a halogen atom or a hydroxyl group.
Patent CA-2611169-A1 (CA)
Title: Projectile or warhead
Inventor: KELLNER GERD
IPC: F42B12/20
Filed: 2005-06-21
Abstract: The aim of the invention is to obtain great final ballistic effectiveness of fragmentation bullets and warheads regardless of the impact speed while using as little explosive material as possible. Said aim is achieved by combining an explosive shell (3) with a damming inner member (4) in connection with an accelerated outer jacket (2). This arrangement results in the best possible conversion of the explosive energy while offering great creative flexibility regarding the design. A wide range of additional possible effects is created by blast-compacting the inner damming member (4). Furthermore, the shape of the inner damming member allows the fragments to obtain a directionally controlled effect. Depending on the caliber and technical design, the amount of explosive material used can be reduced by 50 to 80 percent compared to conventional explosive bullets at comparable fragment speeds or sub-bullet speeds. The explosive material economized is available as additional effective mass. The accelerated jacket (2) can also be entirely or partly composed of preformed fragments or sub-bullets.
Patent CA-2612529-A1 (CA)
Title: System and method for managing content on a digital video recorder
Inventor: KUNKEL GERARD K
IPC: H04N5/445
Filed: 2007-11-28
Abstract: A system for managing a digital video recorder includes a transceiver for receiving program signals from a media source and for transmitting the program signals to a display device. The transceiver is further operative to transmit information regarding the digital video recorder to the display device to generate a user-interface management screen on the display device for use in managing operation of the digital video recorder. The information includes data that is indicative of available recording space on the digital video recorder based on current and scheduled recordings.
Patent CA-2613951-A1 (CA)
Title: Device for dispensing a controlled dose of a flowable material
Inventor: REEVES GEORGE
IPC: B65D83/00
Filed: 2006-07-06
Abstract: A device (10) for applying controlled unitized doses of a flowable material to a surface is disclosed. The device includes a tubular body (20) and a plunger (60). The body has a wall (21) defining a cavity (24), and the body has a first open end (25) and an opposite second end (26) having a dispensing orifice (28). A flowable material is contained in the cavity of the body. The plunger has an outer sleeve (62) dimensioned for surrounding at least a section the body and an inner pushing structure (80) dimensioned for axial movement in the cavity of the body. The device has means for indexed positioning of the second end of the body and an inner end of the inner pushing structure of the plunger relative to each other to provide controlled unitized doses of the flowable material to a surface when the plunger is moved toward the body by a user's hand.
Patent CA-2615617-A1 (CA)
Inventor: FIALHO ARSENIO
IPC: C12P21/04
Filed: 2006-07-19
Abstract: The present invention discloses methods and materials for delivering a cargo compound into a brain cancer cell and/or across the blood-brain barrier.  Delivery of the cargo compound is accomplished by the use of protein transport peptides derived from Neisseria outer membrane proteins, such as Laz. The invention also provides synthetic transit peptides comprised of the pentapeptide AAEAP. The invention further discloses methods for treating cancer, and specifically brain cancer, as well as other brain-related conditions. Further, the invention provides methods of imaging and diagnosing cancer, particular brain cancer.
Patent CA-2617413-A1 (CA)
Title: 2-aminoaryl pyridines as protein kinases inhibitors
Inventor: AUGERI DAVID
IPC: C07D401/14
Filed: 2006-07-31
Abstract: Aryl pyridines of formula (I), compositions comprising them, and their use for the protein kinases related disorders are described.
Patent CA-2618936-A1 (CA)
Title: Hockey helmet with an outer shell made of two different materials
Inventor: COTE DENIS
IPC: A42B3/06
Filed: 2008-01-24
Abstract: The present invention covers a hockey helmet for receiving a head of a player. The helmet comprises an outer shell made of first and second materials having respective first and second flexibilities. The outer shell comprises a front portion for at least partially facing the crown region of the head, a top portion for at least partially facing the top region of the head, a back portion for at least partially facing the back region of the head, an occipital portion for at least partially facing the occipital region of the head, and left and right portions for at least partially facing the left and right side regions of the head, the left and right portions comprising respective left and right projections that extend downwardly in front of the respective left and right ears and left and right sections located above and behind the respective left and right ears wherein one of the occipital portion, left and right projections and left and right sections is made of the second material and wherein the second flexibility is greater from the first flexibility.
Patent CA-2619206-A1 (CA)
Title: Container having an integral internal divider
Inventor: TIBBELS BRIAN J
IPC: B65D5/481
Filed: 2008-01-30
Abstract: A sustainable container includes panels attached to one another to form sidewalls surrounding a central space, and flaps extending from the sidewalls to form a bottom. A divider panel attached to at least one of the panels has upper and lower portions separated by an opening. The container is assembleable from a knockdown state, in which the upper and lower portions of the divider panel are disposed substantially in a single plane of the divider panel, to an assembled state, in which the upper and lower portions of the divider panel are folded in opposite respective directions out of the plane. The upper portion of the divider panel separates first and second cells of the container, and the lower portion of the divider panel separates second and third cells of the container, when the container is in the assembled state.
Patent CA-2619816-A1 (CA)
Inventor: TSUKAMOTO KENICHI
IPC: E04C5/16
Filed: 2006-09-11
Abstract: The invention relates to a reinforcing body (1) for buildings, in particular for buildings made of concrete, comprising several reinforcing rods (2a, 2b) which are connected together by connecting agents (5) on connecting points (4) and are made of fibre-reinforced plastic. The connecting agents (5) comprises connection fibres (6) which are embedded in a plastic matrix (7) and are enrolled several times about the reinforcing rods (2a, 2b) on the connection points (4).
Patent CA-2620067-A1 (CA)
Title: Method and apparatus for selection of virtual antennas
Inventor: KADOUS TAMER
IPC: H04B7/06
Filed: 2006-08-22
Abstract: Techniques for transmitting data from virtual antennas instead of physical antennas are described. Each virtual antenna may be mapped to some or all physical antennas by a different mapping. The performance of different sets of at least one virtual antenna is evaluated based on one or more metrics such as signal quality, throughput, overall rate, and so on. The virtual antenna set with the best performance is selected for use. If the virtual antenna selection is performed by the receiver, then channel state information for the selected virtual antenna set may be sent to the transmitter. The channel state information may convey the selected virtual antenna(s), the signal quality or rate(s) for the selected virtual antenna(s), one or more precoding matrices used to form the selected virtual antenna(s), and so on. The transmitter and/or receiver use the selected virtual antenna(s) for data transmission.
Patent CA-2620403-A1 (CA)
Title: Complex formation method and separation method
Inventor: WADA HENRY GARRETT
IPC: G16B20/30
Filed: 2006-08-24
Abstract: An object of the present invention is to provide a method for forming a complex between an analyte or an analogue thereof, and a substance formable the complex with said analyte or said analogue thereof (the complex forming substance), in a short time and in high reaction efficiency, and a method for separating a complex formed, and a complex forming substance not involved in formation of said complex or an analogue not involved in formation of said complex rapidly, simply and in high accuracy, along with a method for measuring an analyte in a sample in high sensitivity.
Patent CA-2624725-A1 (CA)
Title: Fried food products having reduced fat content
Inventor: KEELER LAURIE J
IPC: A23L5/10
Filed: 2006-10-04
Abstract: Methods of making reduced-fat or fat-free fried food products, and products made according to the methods, in which food pieces are coated with an aqueous adhesion mixture including a protein, and an oil absorption minimizing agent including an edible lipophilic material, where the coating is adhered to the food pieces, in order to provide for food products having the texture, flavor, and other characteristics of conventional full-fat fried food products.  According to a preferred embodiment, the aqueous adhesion mixture includes from about 65 to about 95% by weight water, from about 4 to about 25% by weight protein, from 0 to about 2% by weight hydrocolloid, and from 0 to about 10% by weight protein stabilizing agent.
Patent CA-2626566-A1 (CA)
Title: Method and device for shrinking a heat shrink film placed around a stack of items
Inventor: REINER HANNEN
IPC: B65B53/06
Filed: 2006-10-23
Abstract: A method using heat for shrinking a heat shrink film wrapping placed around a stack of items. The heat shrink film wrapping protrudes on the upper side of the stack of items at least beyond the upper edge of the stack of items to a top sheet film, which is welded to the heat shrink film wrapping. In the method hot gases rising up along the sides of the stack of items are diverted inward, in a direction parallel to the upper side of the stack of items, by a heat diverting and pressing apparatus, which is arranged above the stack of items. The heat diverting and pressing apparatus is for preheating and inwardly folding over the overhang of the heat shrink film wrapping and for preheating the top sheet film in the region of the upper side. The layers of the overhang are joined, by pressing the layers of the heat shrink film onto one another by the heat diverting and pressing apparatus. The invention also relates to an apparatus for carrying out the method.
Patent CA-2628664-A1 (CA)
Title: System for distributing packages and channels to a device
Inventor: COLLINS BRUCE
IPC: H04N21/266
Filed: 2006-11-08
Abstract: A system for distributing packages and channels to a device includes associating weights with the packages and channels. The default ordering of packages on a device display and the default ordering of channels on a program guide is determined according to the weights. In addition, the weights may be used to differentiate functions and conditions that apply to packages and channels.