baber/WOPTO huggingface dataset:
Patent EP-3550024-A1 (EP)
Inventor: QI WEI
IPC: C12N15/867
Filed: 2017-11-13
Abstract: The invention discloses a PDL1 block CAR-T transgenic vector for suppressing immune escape, including: AmpR sequence containing ampicillin resistance gene (SEQ ID NO.1); prokaryotic replicon pUC Ori sequence (SEQ ID NO.2); virus replicon SV40 Ori sequence (SEQ ID NO.3); eWPRE enhanced posttranscriptional regulatory element of hepatitis B virus (SEQ ID NO.11); human EF1a promoter (SEQ ID NO.12); lentiviral packaging cis-elements for lentiviral packaging; humanized single-chain antibody fragment PDL1scFv1 (SEQ ID NO.21), PDL1scFv2 (SEQ ID NO.22), or PDL1scFv3 (SEQ ID NO.23) of human PDL1; IRES ribosome binding sequence (SEQ ID NO.25); IL6 signal peptide (SEQ ID NO.26); human antibody Fc segment (SEQ ID NO.27); and the chimeric antigen receptors of the second or third generation CAR for integrating recognition, transmission and initiation. Also, the invention discloses the preparation method of the vector and its application in the preparation of anti-immune escape drugs.
Patent EP-3552295-A1 (EP)
Inventor: JOHNSTON CESAR
IPC: H02J50/40
Filed: 2017-12-12
Abstract: The method includes detecting, via a wireless communication component of a near- field charging pad, that a receiver is within a threshold distance of the pad. In response to detecting that the receiver is within the threshold distance of the pad, the method includes: determining whether the wireless power receiver has been placed on the pad. In accordance with determining that the receiver has been placed on the pad, the method includes: selectively transmitting, by respective antenna elements included in the plurality of antenna zones, respective test power transmission signals with a first set of transmission characteristics until a determination is made that a particular power-delivery parameter associated with transmission of a respective test power transmission signal by at least one particular antenna zone of the plurality of antenna zones satisfies power-delivery criteria. Upon determining that the particular power-delivery parameter satisfies the power-delivery criteria, the method also includes: transmitting a plurality of additional power transmission signals to the receiver using the at least one particular antenna zone, wherein each additional power transmission signal of the plurality is transmitted with a second set of transmission characteristics, distinct from the first set.
Patent EP-3558306-A1 (EP)
Title: 6,5-fused heteroaryl piperidine ether allosteric modulators of the m4 muscarinic acetylcholine receptor
Inventor: GAO XIAOLEI
IPC: A61K31/435
Filed: 2017-12-18
Abstract: The present invention is directed to 6,5-fused heteroarylpiperidine ether compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.
Patent EP-3565939-A1 (EP)
Inventor: BRAND MARCEL
IPC: E21B4/02
Filed: 2017-12-21
Abstract: An apparatus for use in a wellbore is disclosed that in one non-limiting embodiment includes a rotatable member, a thrust bearing coupled to the rotatable member, wherein the thrust bearing includes a bearing stack that further includes a unitary inner race member that includes a number of axially spaced inner races around an outer surface of the unitary inner race member. A set of bearing elements is placed in each inner race, and a separate outer race secures each set of bearing elements in each inner race.
Patent EP-3469379-A1 (EP)
Inventor: DREWS BRADLEY KENT
IPC: G01N35/10
Filed: 2017-12-21
Abstract: L'invention concerne un instrument d'analyse pouvant effectuer des opérations analytiques sur un analyte qui est combiné à de multiples réactifs avant d'être introduit dans une cellule d'écoulement. L'instrument peut comprendre un bouchon de buse qui aspire des réactifs à partir d'un récepteur, conjointement avec un analyte. Les réactifs peuvent être dirigés vers un volume et peuvent être déplacés de manière répétée dans le volume et hors de celui-ci par cyclage d'une pompe. Les réactifs peuvent être éjectés dans un récepteur de destination, le goutteur à buse favorisant la vorticité chez le récepteur pour améliorer le mélange. L'aspiration et l'éjection répétées à travers le goutteur à buse mélangent efficacement les réactifs et la matrice d'une manière automatisée ou semi-automatisée.
Patent EP-3566293-A1 (EP)
Inventor: WAGONER ROBERT GREGORY
IPC: H02M1/00
Filed: 2017-12-22
Abstract: Systems and methods for grounding power generation systems with silicon carbide MOSFET power converters are provided. A power generation system can include a power generator comprising a multiphase rotor configured to generate multiphase alternating current power at a first voltage and a power converter comprising one or more silicon carbide MOSFETs and an isolation transformer. The power converter can be configured to convert the multiphase alternating current power from the power generator at the first voltage to multiphase alternating current power at a second voltage. The power generation system can be electrically grounded to shunt a leakage current associated with the isolation transformer of the power converter to a ground.
Patent EP-3565404-A1 (EP)
Inventor: SEGUIN KATHERINE
IPC: A01N63/00
Filed: 2017-12-06
Abstract: Novel insecticidal proteins that are toxic to lepidopteran pests are disclosed. The polynucleotides encoding the insecticidal proteins can be used to transform prokaryotic and eukaryotic organisms to express the insecticidal proteins. The recombinant organisms or compositions containing the recombinant organisms or the insecticidal proteins alone or in combination with other pest control agents and an appropriate agricultural carrier can be used to control lepidopteran pests in various environments.
Patent EP-3565036-A1 (EP)
Inventor: SHIMADA KOHEI
IPC: H01M10/12
Filed: 2017-06-13
Abstract: A liquid-type lead storage battery includes a positive electrode plate and a negative electrode plate alternately layered through a separator, wherein the liquid-type lead storage battery further includes a porous film arranged between the positive electrode plate and the negative electrode plate, the positive electrode plate has a positive electrode active material containing PbO<sub>2</sub>, and a ratio (α-PbO<sub>2</sub>/β-PbO<sub>2</sub>) between peak intensities of α-PbO<sub>2</sub>and β-PbO<sub>2</sub>in an X-ray diffraction pattern in the positive electrode active material is 0.60 or less.
Patent EP-3644041-A1 (EP)
Inventor: WANG GUANZHEN
IPC: C12Q1/00
Filed: 2017-06-20
Abstract: The present invention falls within the field of medical apparatuses. Disclosed are a method and a device for identifying platelet aggregation, and a flow cytometer, which are used for accurately giving an alarm about a platelet aggregation during blood cell analysis. The method comprises: detecting a pre-treated blood sample by using a flow cytometry technique so as to acquire scattered light signals and fluorescent light signals of the blood sample, wherein the scattered light signals are forward scattered light signals or side scattered light signals; differentiating between ghost particles and white blood cells by using a fluorescence-scattered light diagram generated by the scattered light signals and the fluorescent light signals of the blood sample; and counting a number of particles in a ghost characteristic region in the fluorescence-scattered light diagram of the blood sample and determining whether the number of particles exceeds a threshold value, and outputting a warning of platelet aggregation if the number of particles exceeds the threshold value.
Patent EP-3667868-A1 (EP)
Inventor: HU YUSHENG
IPC: H02K1/27
Filed: 2017-12-28
Abstract: A tangential motor, a tangential motor rotor and a rotor core thereof are provided. The rotor core includes a rotor body (1) and magnetic steel grooves (2) provided on the rotor body (1). 2N magnetic isolation holes (11) are provided in a rotor magnetic pole between every two adjacent magnetic steel grooves (2). The 2N magnetic isolation holes (11) are symmetrically provided at two sides of a magnetic pole center line of the rotor magnetic pole. A width of each of the magnetic isolation holes (11) increases from a circle center of the rotor body (1) to an outer side of the rotor body. Outer side hole surfaces, close to the outer side of the rotor body (1), of the magnetic isolation holes (11) are arc-shaped surfaces which are concentrically arranged with the rotor body (1). The rotor core is able to reduce the vibration noise of the motor and increase the efficiency of the motor.
Patent EP-3644639-A1 (EP)
Inventor: YANG NING
IPC: H04W36/08
Filed: 2017-08-23
Abstract: A method and a terminal device for cell reselection are provided. The method is applied to a terminal device. A connection between the terminal device and a network device is in a disconnected state, and the network device retains context information of the terminal device, the context information being used to establish a connection between the terminal device and the network device. The method comprises: when the terminal device triggers a cell reselection operation, determining a serving cell of the terminal device according to a configuration of an initial paging area of the terminal device. The method of the embodiments of the present invention can enable the terminal device to remain in an initial paging area to the greatest extent possible, thereby reducing the probability of the terminal device initiating a location update procedure and achieving the purpose of reducing air interface signaling load.
Patent EP-3524983-A1 (EP)
Title: Verfahren zur quantifizierung von gesamtgluten aus getreide in lebensmittelproben
Inventor: WEISS THOMAS
IPC: G01N33/68
Filed: 2018-02-08
Abstract: Die Erfindung betrifft ein Verfahren zur Quantifizierung von Gesamtgluten aus Getreide in Lebensmittelproben. Anwendungsgebiete sind vor allem die Lebensmittelindustrie, Servicelabore und staatliche Kontrolllabore oder die Biotechnologie.Die Erfindung hat das Ziel, den Gesamt-Glutengehalt in Lebensmitteln mit nur einer Messung schnell und preiswert zu bestimmen. Daraus leitet sich die Aufgabe der vorliegenden Erfindung ab, ein Verfahren zu entwickeln, mit dem, basierend auf der Detektion von Prolaminen und Glutelinen, alle potentiell Zöliakie-relevanten Gluten-Proteinfraktionen in Lebensmittelproben entsprechend ihren Massen als Summe quantifiziert werden.Das vorliegende Verfahren basiert auf der gemeinsamen Verwendung spezifischer Prolamin- und Glutelinantikörper als erfindungsgemäßes Kombinationskonjugat zur Detektion von Gesamtgluten. Dabei erfolgt eine Verdünnung der einzelnen Antikörperkonjugate derart, dass der Beitrag der einzelnen Antikörper zur Gesamtsignalstärke dem Anteil der Gluten-Fraktion entspricht, die sie jeweils detektieren.
Patent EP-3525498-A1 (EP)
Title: Electronic devices, systems and methods for vehicular communication
Inventor: CRONIE HARM
IPC: H04W4/46
Filed: 2018-02-08
Abstract: An electronic device that is configured as a host of a distributed ledger, the permission to access the distributed ledger being location based. Applications are in vehicle to vehicle communication, vehicle to infrastructure communication, unmanned aerial vehicle control and retail.
Patent EP-3348575-A1 (EP)
Inventor: PARKOS CHARLES A
IPC: A61K39/395
Filed: 2012-08-10
Abstract: Disclosed are specific binding agents such as antibodies and chimera that bind to JAM-like protein. Also disclosed are heavy chain fragments, light chain fragments, and CDRs of the antibodies, as well as methods related thereto.
Patent EP-3366998-A1 (EP)
Inventor: QUACH SAN
IPC: F23R3/50
Filed: 2018-02-22
Abstract: A combustor (56) for a gas turbine engine (20) includes a support shell (68,70); a first liner panel (72) mounted to the support shell (68,70) via a multiple of studs (100), the first liner panel (72) including a first rail (124a) that extends from a cold side (110) of the first liner panel (72) such that the rail (124a) is non-perpendicular to the cold side (110) and includes a concave surface to at least partially form a curved interface passage (150); and a second liner panel (74) mounted to the support shell (68,70) via a multiple of studs (100), the second liner panel (72) including a second rail (122b) that extends from a cold side (110) of the second liner panel (74) and includes a convex surface to at least partially form the curved interface passage (150).
Patent EP-3379803-A1 (EP)
Title: Verfahren zur übertragung von daten zwischen einer maschinensteuerung und einem externen computer
Inventor: KÖNIG MIRCO
IPC: H04L29/08
Filed: 2018-03-01
Abstract: Zur Übertragung von Daten in Echtzeit zwischen einer Maschinensteuerung (2) und einem externen Computer (3) wird eine Datenverbindung (22) zwischen der Maschinensteuerung (2) und einem mobilen Datenübertragungsgerät (21), etwa einem Smartphone, hergestellt. Weiterhin wird eine Datenverbindung (28) zwischen dem mobilen Datenübertragungsgerät (21) und dem externen Computer (3) hergestellt. Anschließend werden die Daten zwischen der Maschinensteuerung (2) und dem externen Computer (3) über das mobile Datenübertragungsgerät (21) übertragen. Es resultiert ein Übertragungsverfahren, bei dem eine, insbesondere für einen Anwender der Maschinensteuerung, unkomplizierte Datenübertragung mit dem externen Computer erfolgt.
Patent EP-3373324-A1 (EP)
Inventor: LI LINFAN
IPC: H01J49/42
Filed: 2018-03-06
Abstract: A method of quantitative mass analysis of precursor species of different mass-to-charge (m/z) ratios from a single or the same ion injection event is disclosed. A plurality of precursor ion species having different respective m/z ratios are introduced into a mass spectrometer at the same time. The precursor ion species are isolated. A first subset of the isolated precursor ions having a first m/z ratio is fragmented and analyzed. A second subset of the isolated precursor ions having a second m/z ratio is fragmented and analyzed. A first mass spectrum is generated for the fragment ions of the first subset of precursor ions, and a second mass spectrum is generated for the fragment ions of the second subset of precursor ions.
Patent EP-3382268-A1 (EP)
Title: Fahrzeugscheinwerfer und kühlsystem
Inventor: MAYER MATTHIAS
IPC: F21S45/33
Filed: 2018-03-12
Abstract: Fahrzeugscheinwerfer (100), umfassend ein Scheinwerfergehäuse (101), zumindest eine Lichtquelle (102), zumindest eine Projektionsoptik (104), zumindest einen Kühlkanal (107) und ein Kühlmedium. Die zumindest eine Lichtquelle (102) ist eingerichtet, Licht in Form eines Lichtstrahls (105) in Richtung der zumindest einen Projektionsoptik (104) zu emittieren und vor dem Fahrzeug ein Lichtbild auf der Straße auszubilden. Die zumindest eine Lichtquelle (102) und die zumindest eine Projektionsoptik (104) sind innerhalb des Scheinwerfergehäuses (101) gelegen. Der zumindest eine Kühlkanal (107) ist mit zumindest einer Wärmequelle thermisch leitend verbunden und der zumindest eine Kühlkanal (107) ist eingerichtet, bei Durchströmung des Kühlmediums die Wärmequelle zu kühlen. Der zumindest eine Kühlkanal (107) umfasst zumindest eine lösbare Verbindungskupplung (108, 109), die in den Kühlkanal (107) eingefügt ist.
Patent EP-3376067-A1 (EP)
Title: Bodenbearbeitungsmaschine mit schaltgetriebe zwischen antriebsmotor und rotierbarer arbeitsvorrichtung
Inventor: BERNING CHRISTIAN
IPC: F16H3/091
Filed: 2018-03-13
Abstract: Eine Bodenbearbeitungsmaschine (10), umfassend einen Antriebsmotor (42) und eine von dem Antriebsmotor (42) zu einer rotierenden Bewegung antreibbaren Arbeitsvorrichtung (22), wobei der Antriebsmotor (42) mit der Arbeitsvorrichtung (22) unter Zwischenanordnung eines wenigstens zwei Schaltstufen unterschiedlichen Drehmoment-Übertragungsverhältnisses aufweisenden Schaltgetriebes (50) zur Übertragung eines Drehmoments verbunden ist, ist dadurch gekennzeichnet, dass mittels einer ersten Schaltstufe des Schaltgetriebes (50) eine eingangsseitig mit dem Antriebsmotor (42) gekoppelte Eingangswelle (48) des Schaltgetriebes (50) unmittelbar mit einer ausgangsseitig mit der Arbeitsvorrichtung (22) gekoppelten Ausgangswelle (52) des Schaltgetriebes (50) zur gemeinsamen drehzahlgleichen Drehbewegung Drehmoment übertragend verbindbar ist, und dass mittels einer zweiten Schaltstufe des Schaltgetriebes (50) die Eingangswelle (48) unter Zwischenanordnung einer Getriebeanordnung (64) mit der Ausgangswelle (52) zur gemeinsamen drehzahlverschiedenen Drehbewegung Drehmoment übertragend verbindbar ist.
Patent EP-3381679-A1 (EP)
Inventor: HOOGENDOORN WOUTER
IPC: B32B17/10
Filed: 2018-03-28
Abstract: A staircase 1 of which the handrails 3 constitute embodiments of the structural element according to the invention. These handrails 3 are each made from a laminated glass panel 5 of at least two glass plates 7 attached to each other through adhesive interlayers 9 being present between main surfaces of the glass plates facing each other.  To flat parts of the crosscut undersides 11 of the laminated glass panels 5 flat parts of metal connecting elements 13 are attached for connecting the laminated glass panels to a base structural element 15 that forms the steps of the staircase or floor slab. The metal connection elements 13 are exclusively attached to the crosscut underside 11 of the laminated glass panels 5 by an adhesive interlayer 17. This interlayer 17 is of the same kind as the interlayers 9 between the glass plates of the laminated glass panel.
Patent EP-3363307-A1 (EP)
Inventor: GREIM OLIVIER
IPC: A24F40/20
Filed: 2015-05-21
Abstract: An electrically heated aerosol-generating system (10) comprising a tubular portion for receiving an aerosol-forming article (30) and a heater element (16) positioned proximate an end of the tubular portion, the heater element (16) comprising an end face and a thermally conductive substrate comprising a non-stick coating applied over at least a portion of an outer surface of the thermally conductive substrate and at least over the end face of the heater element (16).
Patent EP-3364732-A1 (EP)
Inventor: HARDIN KEITH BRYAN
IPC: H05K3/00
Filed: 2012-10-22
Abstract: A method for manufacturing a Z-directed component for insertion into a mounting hole in a printed circuit board according to one example embodiment includes simultaneously extruding a plurality of materials according to the structure of the Z-directed component to form an extruded object and forming the Z-directed component from the extruded object. In one embodiment, the extruded object is divided into individual Z-directed components. In one embodiment, the timing of extrusion between predetermined sections of one of the materials is varied in order to stagger the sections in the extruded object.
Patent EP-3557199-A1 (EP)
Inventor: BUCHMANN ALICE
IPC: G01G21/28
Filed: 2018-04-17
Abstract: A laboratory balance (1) has a base body (2), a weighing chamber (10) with a weighing chamber floor (3), a weighing chamber rear wall (4), and a draft shield (5,5',5") composed of a top wall (6), a first side wall (7), a second side wall (8) arranged parallel to the first side wall (7), and a front wall (9). The weighing chamber floor (3), the draft shield (5,5',5") and the weighing chamber rear wall (4) together enclose the weighing chamber (10). According to the invention, the weighing chamber rear wall (4) is of modular construction, having at least a base module (15) and a top module (16,16',16"), wherein the base module (15) is connected to the base body (2), and the top module (16,16',16") is connected to the top wall (6) of the draft shield (5,5',5").
Patent EP-3575544-A1 (EP)
Inventor: KRÆMER JON
IPC: E21B33/127
Filed: 2018-05-30
Abstract: The present invention relates to a downhole completion system for providing a well tubular metal structure in a borehole of a well having a top, comprising a well tubular metal structure configured to be arranged in the borehole. The well tubular metal structure having a first end nearest the top and a second end, and at least one annular barrier having a tubular metal part mounted as part of the well tubular metal structure, an expandable metal sleeve surrounding the tubular metal part, each end of the expandable metal sleeve being connected with the tubular metal part defining an annular barrier space, and an expansion opening in the tubular metal part for letting fluid into the annular barrier space to expand the sleeve, and wherein the downhole completion system further comprises a closing unit configured to be in a first position to allow flow through the second end and configured to be in a second position to close the second end, the closing unit comprises a tubular unit part having a first unit end being open and a second unit end being closed, a sliding sleeve arranged on an outer face of the tubular unit part defining a chamber, at least one first opening in the tubular unit part, at least one second opening in the tubular unit part opposite the chamber, the at least one second opening is arranged closer to the first unit end than the at least one first opening, and a ball seat arranged in the tubular unit part between the at least one first opening and the at least one second opening. The invention also relates to a closing unit configured to be in a first position to allow flow through a second end of a well tubular metal structure downhole and configured to be in a second position to close the second end.
Patent EP-3582032-A1 (EP)
Title: Feldgerät mit reduzierter stillstandszeit bei firmware-update
Inventor: ISENMANN ANDREAS
IPC: G05B19/042
Filed: 2018-06-12
Abstract: Feldgerät (1, 1a, 1b), umfassend• Sensor (11) und/oder Aktor (12) zur Messung bzw. Steuerung einer Prozessgröße (51),• primäre Kommunikationsschnittstelle (13a), die zur Übermittlung von Messwerten (11a) des Sensors (11), bzw. zum Empfang von Anweisungen (12a) für die Beeinflussung des Aktors (12), ausgebildet ist,• Mikrocontroller (14a) oder Embedded-System (14b) zur Steuerung der Messwertaufnahme mit dem Sensor (11), bzw. zur Steuerung der Beeinflussung des Aktors (12), auf der Basis einer in einem Programmspeicher (15) hinterlegten Firmware (16),• weiteren Speicher (17) für eine aktualisierte Version (16a) der Firmware (16), und/oder eine Aufnahme (17a) für einen solchen weiteren Speicher (17), sowie• Aktualisierungslogik (18), die dazu ausgebildet ist, nach Aufnahme der aktualisierten Version (16a) der Firmware (16) in weiteren Speicher (17) und nach späterem Eintreten mindestens einer vom Verwender des Feldgeräts (1, 1a, 1b) festgelegten Aktivierungsbedingung (19) den Mikrocontroller (14a), bzw. das Embedded-System (14b), zur Verwendung der aktualisierten Version (16a) der Firmware (16) zu veranlassen.
Patent EP-3451520-A1 (EP)
Inventor: HONG SHOUYU
IPC: H01L25/11
Filed: 2018-06-18
Abstract: A component structure comprises: a first bus bar (410, 610, 710, 1310), having one end extending to a first plane A to form a first connecting terminal (415, 615, 715, 1315); a second bus bar (420, 620, 720, 1320), comprising a front portion of the second bus bar (421, 621, 721, 1321) and a rear portion of the second bus bar (422, 622, 722, 1322), wherein the front portion of the second bus bar is laminated in parallel with the first bus bar, and the rear portion of the second bus bar is extended to a second plane B to form a second connecting terminal (425, 625, 725, 1325); and an external circuit comprising a third bus bar (430, 630, 730, 1330), wherein the third bus bar is settled in parallel with the rear portion of the second bus bar.