baber/WOPTO huggingface dataset:
Patent HU-E035727-T2 (HU)
Title: Pharmaceutical dosage form for oral administration of a bcl-2 family inhibitor
Inventor: PACKHAEUSER CLAUDIA
IPC: A61P35/00
Filed: 2010-06-08
Abstract: The invention relates to a pharmaceutical dosage form which comprises a solid dispersion product comprising N-(4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohex-1-en-1-yl)methyl)piperazin-1-yl)benzoyl)-4-(((1R)-3-(morpholin-4-yl)-1-((phenylsulfanyl)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)benzenesulfonamide or a salt, hydrate or solvate thereof, at least one pharmaceutically acceptable polymer, and at least one pharmaceutically acceptable solubilizer. The invention is further directed to processes for preparing the pharmaceutical dosage form and to use of the dosage form for treating proliferative disorders.
Patent TR-200001447-T2 (TR)
Inventor: BEAUJARD OLIVIER
IPC: G06Q20/00
Filed: 1998-11-16
Abstract: A method for effecting transactions through a telecommunication network by smart cards and telecommunication terminals provided with at least two smart card reading interfaces, one for receiving a subscriber identification smart card dedicated to telephony, the other for receiving a smart card dedicated to one or more applications other than telephony. Communication facilities are added to the subscriber identification card to enable it to control any application card through the telecommunication terminal.
Patent TR-200002620-T2 (TR)
Title: Mineral içeren termoplastik granüller
Inventor: CALHOUN ALLISON ANNE
IPC: C08K9/04
Filed: 1998-12-18
Abstract: Bir termoplastik ürün üretmek üzere termoplastik malzemeye dahil etmek için mineral içeren termoplastik granül; agirlikca en az % 50 inorganik tanecikli malzeme, agirlikca en az % 0,1 bir köpürtücü ajandan olusan bir katki ve bakiye olarak termoplastik bir baglayici ihtiva eder.
Patent TR-200100239-T2 (TR)
Title: Matris metaloproteinazların önlenmesinde kullanılan trisiklik sülfonamitler ve türevleri.
Inventor: O'BRIEN PATRICK MICHAEL
IPC: C07D307/91
Filed: 1999-06-02
Abstract: Söz konusu bulus trisiklik sülfonamit terkipler bunlarin türevleri, hazirlanma yöntemleri ve bilhassa jelatinaz A, kolagenaz-3 ve stromelisin-1 gibi matris metaloproteinazlari önlemek için kullanilan bulusa ait terkiplerin ihtiva edildigi farmasötik bilesimler ile ilgili olup söz konusu farmasötik bilesimler aort anevrizmasi, kalp ve böbrek yetmezligi, artrit, Alzheimer, AIDS, felç gibi muhtelif enflamatuvar hastaliklarin, akut ve kronik nörodejeneratif hastaliklarin tedavisi ve önlenmesinde etkilidir.
Patent TR-200100597-T2 (TR)
Title: Kuvvetli ve yumuşak delikli dokunmamış ağ-yapı
Inventor: FLOHR ANDREAS
IPC: D04H1/54
Filed: 1999-09-01
Abstract: Bir alt bezi gibi bir kullanilip atilabilir emici esya üzerinde bir üst-tabaka olarak kullanilabilecek bir dokunmamis ag-yapi.. Dokunmamis ag-yapi her biri bir baglanmis alana sahip olan iki dis bölge ve bir merkezi bölgeye sahiptir. Dis bölgelerin baglanmis alani, bir yumusak merkezi bölge ve kuvvetli dis bölgelerin temin edilmesi için merkezi bölgenin baglanmis alanindan daha büyüktür.
Patent TR-200102510-T2 (TR)
Inventor: KLEIN JOHANN
IPC: C08F222/20
Filed: 2000-04-07
Abstract: Copolymers (I) obtained by radical copolymerisation of (A) ester(s) of at least difunctional carboxylic acids containing olefinic double bond(s) with alkylene oxide adducts and (B) other radically polymerisable comonomer(s). Independent claims are also included for (a) a process for the production of (I) by copolymerisation of at least two components (A) and (B) as above; (b) preparations containing at least 0.1 wt% (I).
Patent TR-200102775-T2 (TR)
Title: Bir substrat (alt-tabaka)ağartma bileşimi ve yöntemi
Inventor: CARINA RICCARDO FILIPPO
IPC: D06L3/02
Filed: 2000-03-22
Abstract: Bu bulus  substratlarin,atmosfer oksijeni ile, daha hususiyetle belirtmek gerekirse belli bir ligand veya kompleks sinifini katalizör olarak kullanarak katalitik yoldan agartilmalarina iliskin bilesimlere ve yöntemlere iliskindir ve ayrica bu tür bilesimler ve yöntemler için faydali ligandlara ve komplekslere iliskindir. Bu bulus, dokumalarin, örnegin çamasirda yikanacak kumaslarin belli ligand veya kompleks sinifini katalizör olarak kullanmak suretiyle isleme tabi tutulmalarina iliskin bir yönteme, daha belirgin olmak gerekirse atmosfer oksijeni ile agartmanin isleme tabi tutma sonrasinda katalizlendigi bir yönteme de iliskindir.
Patent TR-200102948-T2 (TR)
Title: Bitkinin biyotik ve/veya abiyotik strese karşı güçlendirilmesi için lipoid silisik asit esterlerin kullanımı.
Inventor: KOPP-HOLTWIESCHE BETTINA
IPC: C05G3/70
Filed: 2000-04-22
Abstract: Bulus, zararli mikro-organizmalara ve abiyotik stres faktörlerine karsi bitkinin saglikli büyümesinin güçlendirilmesi için, monomer ve/veya oligomerler ile birlikte, silisik asidin hiç olmazsa kismen lipofil hidrokarbon kisimlar içeren alkollerle olan, lipoid içinde çözünen esterlerinin (lipoid silisik asit esterlerinin) kullanilmasina iliskindir. Lipoit silisik asit esterleri bitkinin kök bölgesine verilerek ve/veya bitkinin toprak üstündeki kismina sürülerek uygulanir.
Patent DE-602004011248-T2 (DE)
Inventor: MONPOUET PASCAL
IPC: A63F9/24
Filed: 2004-10-19
Granted: 2009-01-02
Abstract: The assembly has communicating units e.g. cards (6), each having a radiofrequency identification tag. A game board (1) has detection units to detect the presence, nature and position of the communicating units on the board. Each detection unit has an individual microcontroller connected to a corresponding antenna coil. The set of microcontrollers is connected to a centralized processing electronic circuit.
Patent DE-602004011900-T2 (DE)
Inventor: BAUMEISTER WOLFGANG
IPC: G01N1/28
Filed: 2004-04-28
Granted: 2009-02-26
Abstract: The present invention relates to a method for the detection and/or analysis of the structure of macromolecular complexes and/or macromolecules comprising the steps of (a) purifying or separating said macromolecular complexes and/or macromolecules from a sample containing said macromolecular complexes and/or macromolecules by applying in a porous matrix a separation force in a first dimension (X-axis); (b) transferring in a second dimension (Z-axis) by adsorption forces the macromolecular complexes and/or macromolecules purified or separated in step (a) from the porous matrix onto a carrier wherein said carrier contacts the surface of the porous matrix and is positioned parallel to the surface of said matrix and parallel to the direction of the separation force applied in step (a); (c) immobilizing the macromolecular complexes and/or macromolecules on said carrier after transfer of step (b); and (d) assessing the structure of the macromolecular complexes and/or macromolecules on said carrier after immobilization of step (c).Furthermore, the present invention relates to the use of said method for analyzing whether a subject is afflicted by a disease or prone to developing a disease, wherein said disease is correlated with the presence or absence of protein complexes, and/or virus complexes, and/or bacterial complexes and/or fungal complexes, and/or prion-related complexes.The present invention also relates to a device for carrying out the method of the invention.
Patent DE-602005000654-T2 (DE)
Inventor: BESSON JACK
IPC: B60S1/54
Filed: 2005-04-26
Granted: 2007-11-29
Abstract: The device has an aerodynamic spoiler (5) with a hollow body (7) in two portions (8, 9). The portion (9) is movably mounted in a plane relative to the portion (8) to arrange a transversal slit (11) in between them. External air flowing to the spoiler is sucked via the slit for being displaced to a glass pane. The portion (9) supports a nozzle (19) connected to the portion (8) by a washing water supply duct. The washing water supply duct controls and combines relative displacement of the portions generated by the pressure of the water admitted in the duct.
Patent DE-602005002711-T2 (DE)
Inventor: KEETON WILLIAM B
IPC: B27B17/14
Filed: 2005-09-26
Granted: 2008-07-17
Abstract: A retaining assembly (34) is provided for a tensioning arrangement for adjusting the tension of the cutting chain in the chainsaw. The retaining assembly includes a knob body (35), a lock, and a lever (36). The lock and lever rotate about a common axis, which is perpendicular to an axis of rotation of the retaining assembly. The lock includes a tooth adapted to engage with teeth on a clutch cover of a chainsaw to lock the retaining assembly in place.
Patent DE-602005004811-T2 (DE)
Inventor: HURLEY MEGAN K
IPC: A61Q5/12
Filed: 2005-10-24
Granted: 2009-04-09
Abstract: A personal care composition is provided with a silicone compound and being aesthetically modified for improved skinfeel with a quaternary ammonium salt, the salt having a structure AB, wherein A is a cationic charged component, B is an anionic charged component, and A has one quaternized nitrogen atom, at least two hydroxyl groups and a molecular weight no higher than about 250.
Patent DE-602005005284-T2 (DE)
Inventor: EBERLE WALTER
IPC: G01N33/68
Filed: 2005-11-14
Granted: 2009-04-16
Abstract: The invention is directed to a method for performing a high-throughput test to determine the presence of PrPsc in a tissue sample taken post mortem from brain, the test comprising the workflow of (A) sample preparation, (B) sample treatment, (C) sample analysis, (D) controls, and (E) classifying the results of the analysis as positive or negative. The invention is further directed to preparing a treated biological sample suspected of containing PrPsc such that it is suitable for specific detection of PrPsc, if present, the method comprising the steps of (a) homogenizing the sample; followed by (b) digesting the sample proteolytically by adding to the homogenate Proteinase K and incubating the sample; followed by (c) adding a peptidic protease inhibitor to the incubated mixture of step (b), thereby obtaining a treated biological sample suitable for specific detection of PrPsc, if present. The invention further provides a conditioned microwell plate. In addition, the invention provides a soluble fusion protein comprising one or more epitopes of prion protein as well as a carrier polypeptide.
Patent DE-602005006243-T2 (DE)
Inventor: LAIMER CHRISTOPH
IPC: G06F3/048
Filed: 2005-05-02
Granted: 2009-06-25
Abstract: In a visualization system a three-dimensional scene (43) is projected onto a camera's view projection plane (42) from a camera's defined viewpoint (41) and mapped onto a two-dimensional display. For positioning a pointer (45) in the three-dimensional scene (43), the view of the three-dimensional scene is animated automatically to provide to a user the view of the three-dimensional scene with a kinetic depth effect. The view of the three-dimensional scene is animated by applying a spatial transformation to the three-dimensional scene (43) or the camera. The transformation is applied to the three-dimensional (43) scene or the camera such that the projected view of the pointer (45) remains essentially static. The pointer (45) is positioned based on signals received from the user, while the view is animated. Providing to the user an animated view of the three-dimensional scene with a kinetic depth effect makes it possible for the user to place the pointer (45) in all three dimensions without the need for stereoscopic vision.
Patent DE-60316115-T3 (DE)
Inventor: HISSINK CATHARINA
IPC: A61F2/06
Filed: 2003-02-05
Granted: 2014-01-16
Abstract: The present invention relates to specific DL-lactide- epsilon -caprolactone copolymers and the application of these polymers in the production of biodegradable medical applications. According to the present invention a polymeric material comprising poly(DL-lactide-co- epsilon -caprolactone) is provided, which is obtained by the copolymerization of DL-lactide and  epsilon -caprolactone, having a lactide content of 51-75 mol%, most preferably of 62-69 mol%. The materials of the present invention have excellent mechanical properties and may be used to provide articles for medical application, in particular nerve guides.
Patent DK-1116642-T3 (DK)
Inventor: HOEHNE WOLFRAM
IPC: B61D3/08
Filed: 2000-12-15
Granted: 2004-01-05
Abstract: The bottom end (5) of the stanchion (2) facing the holding pocket (4) has lengthways guide slots (6) engaged transversely by securement bolts (7). A ball-fitted (8) securement hook (9) projecting beyond the stanchion end (5) is allocated a slotted link (10) to take the hook in association with a guide rail equipped with receiver notches for the hook (9). The slots (6) are closed off at the ends and each slit open (13) at the side for the respective bolt (7) and the hook ball (8) is adapted to passed through the link (10) opening (14). The shaft (15) of the hook (9) bears slidably on the link. An endstop spaced from the bottom end (15) of the stanchion (2) limits the depth to which the shaft (15) rides into the slotted link (10).
Patent DK-1152839-T3 (DK)
Inventor: DRESS PETER
IPC: B05C11/08
Filed: 2000-01-19
Granted: 2003-03-10
Abstract: To achieve a uniform coating of a substrate, with an apparatus and a method for coating substrates, according to which the substrate is supported on a substrate holder in such a way that a substrate surface that is to be coated is exposed, and the substrate is rotated together with the substrate holder, a cover can be secured to the substrate holder and together with the substrate holder forms a sealed chamber for the substrate.
Patent DK-1183218-T3 (DK)
Inventor: BASURA DANKO
IPC: C04B28/02
Filed: 2000-04-14
Granted: 2003-07-21
Abstract: Flowable hardenable cast composition comprises a binder, especially cement, and a light aggregate of broken foamed glass.
Patent DK-1086137-T3 (DK)
Inventor: FIGDOR CARL GUSTAV
IPC: A61K39/00
Filed: 2000-04-19
Granted: 2008-10-27
Abstract: Use of a compound (I) that binds to a C-type lectin (II) on the surface of a dendritic cell (DC) for producing a composition for modulating (especially reducing) the immune response in an animal (particularly human or other mammal), provided that (II) is not the DEC-205 receptor. Independent claims are also included for the following: (1) an antibody (Ab), preferably monoclonal, directed against a C-type lectin (IIa) having a fully defined sequence of about 400 amino acids (given in the specification) or its natural variants, equivalents, parts, fragments or epitopes; (2) a pharmaceutical composition containing Ab and at least one carrier, excipient, adjuvant or auxiliary; (3) a combination of (I) attached to an antigen (Ag) or its fragment; (4) a method for producing, isolating and/or purifying DC from a biological sample or culture medium; and (5) DC prepared by method in (4). ACTIVITY : Immunosuppressant; immunostimulant; anti-allergic; antiviral; antitumor; antibacterial; antiprotozoal. MECHANISM OF ACTION : (I) mediates adhesion between DC and other cells by inhibiting interaction between (II) and (i) an ICAM (intracellular adhesion molecule) on T cells or (ii) gp 120 on HIV (human immune deficiency virus)-infected cells. A new (II), DC-SIGN, is not only involved in DC-T cell clumping but is also a major HIV receptor. Cells of the leukemia line K562 were transfected to express ICAM-3 and tested for binding to DC. Clumping between the cells was inhibited by antibodies directed against DC-SIGN, and DC-mediated T cell proliferation was then only about 1/3 of that in an antibody-free medium. The effect was greatly increased when anti-LFA3 antibodies were additionally present (practically no proliferation).
Patent DK-1188052-T3 (DK)
Inventor: CEDERGREN ANDERS
IPC: G01N33/18
Filed: 2000-05-18
Granted: 2008-06-09
Abstract: Karl Fischer reagent comprising iodide, sulphur dioxide with an initial concentration above 0.5 M, and imidazole/imidazole derivative dissolved in alcoholic solvent, whereby the molar ratio between the initial imidazole/imidazole derivative concentration and the initial sulphur dioxide concentration is above 10. The reagent contains a modifying substance that is an aliphatic hydrocarbon, or a primary or secondary alcohol, or a combination thereof. A method for the determination of water content by means of Karl Fischer coulometric titration in a diaphragm-free cell, whereby the Karl Fischer reagent is used, and the coulometric titration is carried out in a diaphragm-free cell. Use of the Karl Fischer reagent in a method for the determination of water content by means of coulometric titration.
Patent DK-1234154-T3 (DK)
Inventor: NISKE JOERGEN
IPC: F28F9/013
Filed: 2000-10-25
Granted: 2005-08-15
Abstract: A heat exchanger comprising a large number of flexible individual elements, has supply and discharge devices for the heat exchanger media and also has, for these elements, tension devices which expand during heating. The tensioning of the individual elements, which are adhesively bonded at each of their two ends into slots of end plates, takes place by the application of the required forces to the end plates. A heat exchanger of this type is illustrated in FIG. 1.
Patent DK-1227897-T3 (DK)
Inventor: GILLET FRANCOIS
IPC: B07C3/02
Filed: 2000-10-25
Granted: 2003-11-10
Abstract: The machine for merging batches of objects, in particular batches (L1, L2) of mail items (A) previously ordered according to their order of distribution in the mailman's round, so as to constitute a single batch of mail items which is ordered according to the mailman's round comprises: a) destacking units (D1, D2), b) linked to the exit of each destacking unit, one or more dynamic-storage magazines (M11-M22) in each of which the items are moved in series around a storage loop, and interposed between each destacking unit and a dynamic-storage magazine, a device (DL1, DL2) for reading a classifying cue on each destacked object; c) a conveyor (CS) in which the mail items are moved in series and to which the dynamic-storage magazines are linked in parallel, d) a control/command unit (U) for the destacking units and for the dynamic-storage magazines which, on the basis of the classifying cues read by the reading devices, controls the transferring of the mail items from the destacking units to the dynamic-storage magazines and then from the dynamic-storage magazines to the conveyor.
Patent DK-1261442-T3 (DK)
Inventor: RITTER OLAF
IPC: B21D1/06
Filed: 2000-12-15
Granted: 2005-12-12
Abstract: An arrangement for removing dents from sheet metal contains a lever, which at a support point can be supported on the metal sheet. A handle is fitted to the lever end. To the lever can be connected a tension element, which can be connected to an adapter connected to the metal sheet.
Patent DK-1239774-T3 (DK)
Inventor: YAMAMOTO RONALD K
IPC: A61B8/10
Filed: 2000-12-11
Granted: 2006-01-16
Abstract: The invention relates to a novel apparatus for the treatment of ocular disease, particularly glaucoma. The apparatus consists of a locating device to locate Schlemm's Canal within the anterior portion of the eye and a surgical tool to access the canal for treatment. The apparatus allows for guided, minimally invasive surgical access to Schlemm's Canal to enable surgical procedures to be performed on the canal and trabecular meshwork to reduce intraocular pressure. The apparatus may also deliver devices or substances to Schlemm's Canal in the treatment of glaucoma.
Patent DK-1219550-T3 (DK)
Inventor: GULDENFELS DIETER
IPC: B65G17/08
Filed: 2001-12-18
Granted: 2005-09-05
Abstract: A conveying apparatus comprises a modular belt (70) having a plurality of modules (73, 80) connected to adjacent modules (73, 80) and articulated by pivot rods (76) that extend through openings in the link ends (72) of the modules (73, 80). The openings extend transverse to the direction of belt travel. The apparatus also includes a drive sprocket having a plurality of teeth (58, 61) disposed around its perimeter. Each tooth (58, 61) has a center driving surface (64) and a link end driving surface (67). The teeth (58, 61) are disposed such that each belt module (73, 80) may be driven in either direction from the center by one of the teeth (58, 61) and simultaneously driven at a link end (72) by one of the other teeth (58, 61) such that there is positive engagement with each belt module (73, 80) by two teeth (58, 61). <IMAGE>
Patent DK-1252163-T3 (DK)
Inventor: TOLLMANN KAROLA
IPC: C07D471/04
Filed: 2001-01-31
Granted: 2004-01-19
Abstract: 4-Pyridyl- or 4-pyrimidinyl-substituted fused bicyclic pyrrole derivatives (I) are new. Fused pyrrole derivatives of formula (I) and their optical isomers, salts and readily physiologically hydrolyzable esters are new: [Image] one of R 1-R 34-pyridyl, 2,4-pyrimidyl (sic) or 3-amino-2,4-pyrimidyl (sic) (optionally substituted by 1 or 2 1-4C alkyl or halo); and a second of R 1-R 3phenyl or thienyl (both optionally substituted by 1 or 2 1-4C alkyl or halo); and the third of R 1-R 3H, COOH, (1-6C) alkoxycarbonyl, CH 2OH or 1-6C alkyl; R 4, R 5H or 1-6C alkyl; X : CH 2, S or O; and n : 1 or 2. (N.B. Formulae given in the disclosure suggest that '2,4-pyrimidyl' should be 4-pyrimidyl and that '3-amino-2,4-pyrimidyl' should be 2-amino-4-pyrimidyl). - ACTIVITY : Immunomodulator; immunosuppressive; cytostatic; neuroprotective; antiarthritic; antiinflammatory; antibacterial; respiratory. - MECHANISM OF ACTION : Cytokine release inhibitor; 5-lipoxygenase inhibitor; cyclooxygenase-1 inhibitor; cyclooxygenase-2 inhibitor. In particular (I) inhibit the release of inflammatory mediators such as tumor necrosis factor-alpha (TNFalpha ), interleukin-1beta (IL-1beta ), leukotriene B4 (LTB4) and prostaglandin E2 (PGE2). (3-(4-Fluorophenyl)-2-(4-pyridyl)-6,7-dihydro-5H-pyrrolizin-1-yl)-met hanol (Ia) had IC 50 values of 4.0 MicroM and 5.0 MicroM respectively for inhibition of Escherichia coli 026:B6 lipopolysaccharide-induced release of TNFalpha and IL-1beta in human peripheral blood mononuclear cells.
Patent DK-1268479-T3 (DK)
Inventor: LI XIAOBING
IPC: C07D403/12
Filed: 2001-03-29
Granted: 2004-04-19
Abstract: The invention features pharmaceutically-active indolizines and tetrahydroindolizines that are each substituted with phenyl, methods of making them, and methods of using them.
Patent DK-1303258-T3 (DK)
Inventor: ROGUEDA PHILIPPE
IPC: A61K31/427
Filed: 2001-07-10
Granted: 2007-01-22
Abstract: The present invention relates to a stable pharmaceutical aerosol formulation intended for inhalation. The formulation contains an active substance, an aerosol propellant, a polar flurorinated molecule and an excipient. The preferred propellant is HFA 134a or HFA 227 or a mixture thereof.
Patent DK-1337779-T3 (DK)
Inventor: SUNDHOLM GOERAN
IPC: F16L19/08
Filed: 2001-10-23
Granted: 2006-08-28
Abstract: A pipe joint for joining a tubular component (1) to a receiving piece (2), the pipe joint comprising a fitting body (3) having a recess (8), a tightening nut (6a) having a first thread (7a), the fitting body having a corresponding thread (4), and a cutting ring (9) being arranged to be pressed between a wedge-like wall portion (10) of the recess, and the tubular component when the tightening nut is tightened. In order that the pipe joint could be tightened to form a leak-proof and strong joint using low torque, which enables the use of small tools applicable in confined spaces, the pipe joint comprises a supplementary nut (6b) having a thread (7c) whose handedness corresponds to that of the first thread (7a) but is smaller, the tightening nut comprising a second thread (7b) corresponding to that of the supplementary nut.
Patent DK-1392248-T3 (DK)
Inventor: SCHUETZ GREGOR
IPC: A61K9/14
Filed: 2002-05-23
Granted: 2007-11-12
Abstract: The invention relates to a method for the solvent-free preparation of a homogenizate, especially for implants or microparticles, wherein one or more polymers and one or more active constituents, as raw materials, are homogenized together below the glass transition temperature of the polymer(s) and, when homogenization is complete, brought to room temperature.