baber/WOPTO huggingface dataset:
Patent AU-600403-B2 (AU)
Title: Process for preparing 2 beta-substituted-methylpenicillin derivatives
Inventor: TORII SIGERU
IPC: C07D499/00
Filed: 1989-02-23
Granted: 1990-08-09
Abstract: A process for preparing a 2 beta -substituted-methylpenicillin compound of the formula <CHEM> wherein -N Y is an optionally substituted heterocyclic group containing 2 to 4 nitrogen atoms as the hetero atom in the ring structure, and R1 is a penicillin carboxyl protecting group, the process comprising reacting an azetidinonedisulfide compound of the formula <CHEM> wherein R1 is as defined above and R is a substituted or unsubstituted heterocyclic group with a nitrogen-containing heterocyclic compound of the formula <CHEM>  wherein <CHEM> is as defined above in the presence of a metal compound. n
Patent AU-753716-B2 (AU)
Title: Cyclin dependent kinase inhibitors
Inventor: GRIFFIN ROGER JOHN
IPC: A61P35/00
Filed: 1999-03-29
Granted: 2002-10-24
Abstract: A range is disclosed of pyrimidine derivatives (I) which can act as inhibitors of cyclin dependent kinases (CDK's) and which thereby can provide useful therapeutic compounds for use in treatment of tumours or other cell proliferation disorders. The compounds of this invention bind to CDK molecules in a manner that appears to differ from that of known CDK inhibitors such as olomoucine and roscovitine.
Patent AU-664590-B2 (AU)
Title: A shock absorber
Inventor: LINDQVIST HANS
IPC: B61D11/00
Filed: 1993-01-04
Granted: 1995-11-23
Abstract: The present invention relates to a shock absorber (1) which is provided with a fastener device (70) for attachment of the absorber to a supportive surface (100) to be protected against the shock of impact forces. The shock absorber (1) includes an external element (10) and a shock absorbing bar (20) which is accommodated in an aperture (15) in the external element. The external element (10) also includes an aperture for accommodating the fastener device (70). The shock absorbing bar (20) is made of an impact absorbing material and is provided with recesses (21-26). The invention also relates to the use of an inventive shock absorber and also to a method of making subsequent adjustments thereto.
Patent AU-673661-B2 (AU)
Title: Child resistant closure with protective flange and canted upper wall
Inventor: VANGE DONALD H LA
IPC: B65D47/30
Filed: 1992-12-29
Granted: 1996-11-21
Abstract: A child resistant dispensing closure having a cap and a spout mounted thereon for rotation about a substantially horizontal axis. The upper surface of the spout is provided with a plurality of ribs, each of which has a distinct energy plane. Only one rib, usually, the rearmost, allows sufficient purchase to produce the force vector necessary to initiate rotation of the spout when a manual force is applied thereto. The cap includes a cylindrical skirt with a frusto-conical section extending upwardly therefrom. A protective flange extends upwardly about the perimeter of the upper end of the frusto-conical section to deter unauthorized access to the spout. The upper wall of said cap is canted at an acute angle to a horizontal plane passing through the cylindrical skirt of the cap, so that the spout is further recessed within the protective flange.
Patent AU-663167-B2 (AU)
Title: Drug delivery system for the simultaneous delivery of drugs activatable by enzymes and light
Inventor: KOPECEK JINDRICH
IPC: A61K47/48
Filed: 1993-01-21
Granted: 1995-09-28
Abstract: Compositions for the treatment of cancerous tissues in warm-blooded animals containing both an anticancer drug and a photoactivatable drug attached to copolymeric carriers are made up of a member selected from the group consisting of (a) a copolymeric carrier having attached thereto both an anticancer drug and a photoactivatable drug, (b) a mixture of copolymeric carriers wherein one copolymeric carrier has attached an anticancer drug and the other copolymeric carrier has attached a photoactivatable drug and (c) a combination of (a) and (b). The anticancer drug is attached to the polymeric carrier by side-chains which are stable in the blood stream of the warm-blooded animal but susceptible to hydrolysis by lysosomal enzymes intracellularly. The photoactivatable drug is attached by either the same degradable side-chain or by a non-degradable attachment. The polymer carrier may optionally contain a targeting moiety. Upon administration polymeric macromolecules enter targeted cancer cells by pinocytosis which reduces the side effects normally elicited by the free drugs. A time lag is allowed following administration for optimal uptake of the copolymers in the cancerous tissue for the anticancer agent to begin to take effect. Then a light sources of the appropriate wavelength and energy is to activate the photoactivatable drug. The combined effect of the anticancer agent and photoactivatable drug provides greater cell destruction at reduced dosages and side effects.
Patent AU-622464-B2 (AU)
Title: Polymer sulphomyl derivatives
Inventor: HENDY BRIAN NORMAN
IPC: C08G65/48
Filed: 1989-07-28
Granted: 1992-04-09
Abstract: A process for making a polymer carrying a plurality of pendant groups SO2Z min  (where Z min  is halogen) comprises reacting with an inorganic acid halide a substantially water-insoluble derivative of the corresponding polymer sulphonic acid with cations of valency 2, 3 or 4. The process is especially useful when the polymer sulphonic acid is one which in free acid form or monovalent cation salt form is soluble in or heavily swollen by water at temperatures in the range 0-30 DEG C. Suitably the polymer sulphonic acid is derived from a polyarylether-sulphone or -ketone or -sulphone/-ketone copolymer containing dioxyphenylene groups.
Patent AU-689981-B2 (AU)
Title: A variable binding device or sheet holder of the type with rings for a file for documents with perforated sheets
Inventor: BOCCACCI ROBERTO
IPC: B42F13/16
Filed: 1995-11-13
Granted: 1998-04-09
Abstract: A binding device or sheet holder of the ring type for a file for documents with perforated sheets, comprising at least one base plate (1), a pair of uprights (2), each provided with a terminating end with a retention enlargement (2a); a pair of straight elastic tubular elements (3), with an external diameter which is smaller than that of the holes (4) of the sheets (5), having a hollow portion (3a) and a solid portion (3b), one following the other. The hollow portion (3a), capable of receiving slidingly the enlargement (2a), has at its free end an elastically deformable travel limit (6) facing towards the inside and intended to engage in abutment manner with the enlargement (2a). The solid portion (3b) has at its free end a releasable engagement means, interacting with a corresponding means of the other elastic tubular element (3); the releasable engagement means being such that they do not interrupt the continuity of dimension and shape of the elastic tubular elements (3).
Patent AU-783887-B2 (AU)
Title: Medical device with position sensor having accuracy at high temperatures
Inventor: GOVARI ASSAF
IPC: G01D5/20
Filed: 2002-05-15
Granted: 2005-12-22
Abstract: A medical device and position sensor combination for use in medical applications comprises a position sensor having a core made of a high permeable material . The core material is made of a Wiegand effect material comprising a mixture of cobalt, vanadium, and iron. The position sensor has an outer diameter of approximately 0.4mm and is used in a medical device having an outer diameter of approximately 0.67mm. <IMAGE>
Patent AU-741938-B2 (AU)
Title: Improvements in security documents and substrates therefor
Inventor: AMES CHRISTOPHER JOHN
IPC: B42D15/10
Filed: 1999-06-15
Granted: 2001-12-13
Abstract: A substrate for producing security documents such as banknotes, cheques and passports which are required to provide a high degree of security against imitation comprises a first layer (16) of biaxially oriented polymeric film laminated together with a second layer (15) of biaxially oriented polymeric film with a metallic layer (18) between, and a third layer (14) of biaxially oriented polymeric film laminated to the second layer with a partially metallised metallic layer (19) therebetween, the metal in each metallic layer being the same or visually similar. At least one metallic layer may provide an electrically conductive path along the width or length of the substrate. A magnetic material may be present between two metallic layers. A layer of polarising material or a dichroic coating may be present on the surfaces of the substrate.
Patent AU-684465-B2 (AU)
Title: Use of alpha,w dicarboxylic acids as fibrinogen reducers
Inventor: PILL JOHANNES
IPC: A61K31/20
Filed: 1993-07-17
Granted: 1997-12-18
Abstract: PCT No. PCT/EP93/01894 Sec. 371 Date Jan. 25, 1995 Sec. 102(e) Date Jan. 25, 1995 PCT Filed Jul. 17, 1993 PCT Pub. No. WO94/02128 PCT Pub. Date Feb. 3, 1994Compounds of  alpha , omega -dicarboxylic acids of the formula I    <IMAGE>  (I)  in which X and Y, which can be the same or different, signify hydrogen, halogen, C1-C6-alkyl, C1-C6-alkoxy, hydroxyl, cyano, carboxyl, C1-C6-alkoxycarbonyl or carbamoyl, R1 and R2, which can be the same or different, hydrogen or C1-C6-alkyl and Q a linear saturated or unsaturated alkylene chain with 2-14 C-atoms in which one or more C-atoms can be replaced by cyclohexyl rings, phenyl or heterocycles, as well as of their in vivo-hydrolysable carboxylic acid derivatives for the preparation of medicaments with fibrinogen-lowering action.
Patent AU-685751-B2 (AU)
Title: Needle protected syringe
Inventor: ADAMS ROBERT D
IPC: A61M5/32
Filed: 1993-06-15
Granted: 1998-01-29
Abstract: An improved syringe of the type having a hollow body which is closed at one end by an injection means and is open at the other end, the open end receives an elongated plunger means which moves through the hollow body and forces the contents of the body through the injection means. The improvement is comprised of a resilient compressive member which retracts the injection means into a protective covering.
Patent AU-641130-B2 (AU)
Title: Coded cuvette for use in testing apparatus
Inventor: FROEHLICH JOHN A
IPC: G01N21/03
Filed: 1989-11-16
Granted: 1993-09-16
Abstract: Optical encoding of a cuvette or other object is provided by means of multiple facets molded integrally into flanges or other portions of the object, which facets selectively refract light passing therethrough in accordance with a predetermined code. The detector for the coded light includes a separate detector for each code state of the facets, with the detector having a different output when no facets are between a light source and the detectors. The facets are preferably bevels, which are selectively angled in accordance with the code.
Patent AU-744719-B2 (AU)
Title: Nucleotide compounds including a rigid linker
Inventor: KAHN SHAHEER H
IPC: C12Q1/6869
Filed: 1999-06-02
Granted: 2002-02-28
Abstract: A nucleoside/tide compound having the structure: NUC-L-S-LB/LG, is described wherein NUC is a nucleoside/tide having a nucleobase portion B, L is a rigid linkage, S is a spacer; and LB/LG is a member of a linkage pair or a label. NUC is attached to L through B such that when B is a purine, L is attached to the 8-position of the purine, when B is 7-deazapurine, L is attached to the 7-position of the 7-deazapurine, and when B is pyrimidine, L is attached to the 5-position of the pyrimidine. In an important aspect of the invention, L has the structure (a) wherein each of n, o and p are integers ranging from 0 to 3, and the sum of n, o and p is at least 2, and each of W, X, Y and Z is selected from the group consisting of carbon and nitrogen. The invention further includes polynucleotide compounds comprising the nucleoside/tide, and primer extension methods utilizing the nucleoside/tide, particularly when used in combination with certain mutant polymerase enzymes.
Patent AU-603541-B2 (AU)
Title: Preparation of strains of bacillus thuringensis having an improved activity against certain lepidopterous pests and novel strain produced thereby
Inventor: BURGES DENIS HORACE
IPC: A01N63/23
Filed: 1985-10-07
Granted: 1990-11-22
Abstract: The invention relates to a strain of Bacillus thuringiensis , GC 91, a sample of which has been deposited under the accession number NCTC 11821, or a derivative or mutant thereof having entomocidal activity against lepidopterous pests. The invention also relates to a process for producing a strain of Bacillus thuringiensis having improved entomocidal properties by combining into a single strain by plasmid transfer the different entomocidal properties of two respective starting strains. The new strains thus produced are useful in entomicidal compositions.
Patent AU-623477-B2 (AU)
Title: Hydrothermal process for preparing potassium silicate solutions with a high sio2:k2o molar ratio
Inventor: NOVOTNY RUDOLF
IPC: C01B33/32
Filed: 1990-01-22
Granted: 1992-05-14
Abstract: The direct hydrothermal production of high purity potassium silicate solutions having a high SiO2: K2O molar ratio by reaction of a silicon dioxide source with aqueous potassium hydroxide solutions is made possible by using a silicon dioxide source that contains a sufficient fraction of cristobalite phase, or by conditioning other crystalline forms of silicon dioxide by heating at or above 1100 DEG C., but below the melting point of silica, before the hydrothermal treatment. Preferably the potassium hydroxide solution has a concentration range of 10 to 40% by weight, and the reaction is carried out in a closed pressure reactor at temperatures of 150 DEG to 300 DEG  C. and under saturated steam pressures corresponding to those temperatures.
Patent AU-569018-B2 (AU)
Title: Rotatable and height adjustable stand
Inventor: KORTH BERND
IPC: A47F7/19
Filed: 1985-11-08
Granted: 1988-01-14
Abstract: The extension column (3) which is telescopically adjustable inside a vertical tube (2) and is optionally rotatable relative to the vertical tube (2) is supported on the latter by a radial and axial pivot bearing arrangement (11, 14) and a height-fixing device comprising a housing (16) and a coupling element (15) preferably in the form of a slide (15) which is supported on a bearing ring (14) which in turn sits on the bearing surface (13) of a support flange (11) supported by the vertical tube (2). The height-fixing slide (15) is mounted in a slide housing (16), which surrounds the bearing ring (14) and the support flange (11), and is against the restoring force of a return spring (27) transferable from a coupled position on the extension column (3) into a release position in which the extension column (3) is freely movable vertically.
Patent AU-716731-B2 (AU)
Title: Monoclonal antibody reacting specifically with Fas ligand and process for producing the same
Inventor: KAYAGAKI NOBUHIKO
IPC: C12P21/08
Filed: 1996-03-21
Granted: 2000-03-02
Abstract: A monoclonal antibody reacting specifically with Fas ligands or the active fragment thereof; a process for producing a monoclonal antibody reacting specifically with Fas ligands; hybridomas producing a monoclonal antibody which reacts specifically with Fas ligands existing on the cell surface or soluble ligands; a method for detecting Fas ligands in a solution; and a kit for detecting Fas ligands which comprises a combination of monoclonal antibodies for Fas ligands.
Patent AU-670458-B2 (AU)
Title: Iodinated aromatic compounds
Inventor: ILLIG CARL R
IPC: C07C233/88
Filed: 1993-11-05
Granted: 1996-07-18
Abstract: Compounds having the structure <CHEM> wherein (Z &rparstr& COO is the residue of an iodinated aromatic acid;     n is an integer from 0 to 6; R<1> and R<2> are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy or aryloxy; R<3> and R<4> are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy, aryloxy, halogen, hydroxy, acylamino, acetamidoalkyl, COO-alkyl and cyano; Q represents the atoms necessary to complete a carbocyclic or heterocyclic unsaturated mono- or bicyclic aromatic ring; and R<5> is H, alkyl, cycloalkyl, aryl, aralkyl, alkoxy, aryloxy, halogen, hydroxy, amino, acylamino, alkoxyalkyl, fluoroalkyl, acetamidoalkyl, COO-alkyl, cyano, carboxamido, sulfonate, sulfonamido, ureido, or carbamyl are useful as contrast agents in x-ray imaging compositions and methods for x-ray diagnostic imaging.
Patent AU-671863-B2 (AU)
Title: Electrochemical energy storage and/or power delivery cell with pH control
Inventor: ZITO RALPH
IPC: H01M8/04
Filed: 1993-10-13
Granted: 1996-09-12
Abstract: An electrochemical process for energy storage and/or power generation and apparatus comprises cell array of unit cells (10), each cell comprising a +ve electrode (12) and a -ve electrode (14) with a membrane in each cell dividing it into +ve and -ve chambers (22C and 24C) for catholyte and anolyte solutions (22, 24) which are recirculated through separate pumps (26, 28) and storage tanks (32, 34) and back to the chambers. Mid electrodes, between adjacent cells in the array, provide both a +ve side and a -ve side. A bromine-sulfur couple may be employed. Means are provided to compensate for pH changes and/or changes in hydroxyl ion concentration in the +ve and/or the -ve sides of the array of cells. Means are provided to affect some limited occurrence of trans-membrane migration or other losses of bromine, sulfur and/or water and to limit the effects of bromine acidification, while affording high energy storage and high power with stable operation over long periods and to maintain output power and voltage at high levels throughout substantially all the discharge cycle.
Patent AU-685067-B2 (AU)
Title: Therapeutic and diagnostic methods and compositions based on notch proteins and nucleic acids
Inventor: ARTAVANIS-TSAKONAS SPYRIDON
IPC: C12N15/09
Filed: 1993-09-30
Granted: 1998-01-15
Abstract: The present invention relates to pharmaceutical compositions comprising a fragment of Serrate protein or a derivative or analog of said fragment, or comprising a derivative or analog of a Serrate protein, or comprising a protein comprising such a fragment, derivative or analog, the fragments, derivatives, analogs and proteins being characterized by the ability  in vitro,  when expressed on the surface of a first cell, to bind to a Notch protein expressed on the surface of a second cell. The invention also relates to chimeric proteins comprising said Serrate fragments joined via a peptide bond to a protein sequence of a protein different from the Serrate protein, and to nucleic acids encoding said fragments of a Serrate protein, and encoding said chimeric proteins. According to the invention, said fragments, derivatives, analogs, and proteins, said chimeric proteins and said nucleic acids may be used as a medicament, for example, in treating or preventing malignancy in a subject.
Patent AU-767090-B2 (AU)
Title: Methods for stabilizing liquid nutritional products and products so stabilized
Inventor: FUCHS EILEEN C
IPC: A23L29/238
Filed: 2000-04-13
Granted: 2003-10-30
Abstract: Nutritional solutions and methods of making same are disclosed. The solutions include protein, lipid, and a carbohydrate source including high amylose starch and guar gum.
Patent AU-635935-B2 (AU)
Title: Production of vascular endothelial cell growth factor and dna encoding same
IPC: C07K14/52
Filed: 1990-05-09
Granted: 1993-04-08
Abstract: DNA isolates coding for a vascular endothelial cell growth factor may be used to produce the protein via recombinant expression systems. Such protein is useful therapeutically to treat conditions in which a selective action on the vascular endothelial cells, in the absence of excessive connective tissue proliferation, is desirable.
Patent AU-780815-B2 (AU)
Title: Methods and products for manipulating uncoupling protein expression
Inventor: NEWELL MARTHA K
IPC: C12N5/0787
Filed: 2000-06-22
Granted: 2005-04-21
Abstract: The invention is based in part on the discovery that uncoupling proteins (UCPs) are expressed in the plasma membrane of rapidly dividing cells but not of growth arrested, chemotherapy resistant cells. It has also been found according to the invention that UCP is expressed in the lysosomal membrane under certain metabolic conditions. Thus the invention is methods, products, screening assays and kits relating to the manipulation of UCP expression within cellular and intracellular membranes.
Patent AU-532120-B2 (AU)
Title: Chromophoric cephalosporins
Inventor: SCHINDLER PETER
IPC: C12Q1/34
Filed: 1980-04-23
Granted: 1983-09-15
Abstract: A chromophoric cephalosporin composition having the formula   <IMAGE> is utilized for the detection of  beta -lactamases. Detection of beta -lactomases can be carried out by diluting the compound in solution or by a test strip carrier.
Patent AU-747060-B2 (AU)
Title: Anti-reflux esophageal prosthesis
Inventor: DUA KULWINDER S
IPC: A61F2/04
Filed: 1999-08-31
Granted: 2002-05-09
Abstract: An esophageal prosthesis (10) for preventing reflux of gastric fluids through the esophagus. The esophageal prosthesis process includes a tubular frame (11) with a sleeve (13) disposed around and longitudinally along the tubular frame as well as extending from the distal end (14) of the frame. The lower portion (28) of the sleeve has a readily collapsible lumen (15) that forms a one-way valve for preventing the reflux of gastric fluids in an antegrade manner through the esophagus. Fluids however readily flow through the sleeve in a antegrade direction. In response to a pressure build up in the stomach of a patient wanting to belch or vomit, the lower portion of the sleeve inverts through the passage (12) of the tubular frame, thereby relieving the pressure build up or voiding the patient's stomach. The tubular frame includes a plurality (19) of self-expanding zig-zag wire stents (20, 21, and 23) that maintain the patency of the esophagus and, in particular, the lower esophageal sphincter and any tumor that is causing stricture of the esophagus.
Patent AU-533413-B2 (AU)
Title: Aqueous dispersion of plastics
Inventor: STREITBERGER HANS-JPACHIM
IPC: C25D13/06
Filed: 1980-05-23
Granted: 1983-11-24
Abstract: An aqueous dispersion based on an acid-protonized reaction product from (a) Mannich bases free from epoxide groups, from (a1) condensed phenols free from ether groups with at least two aromatic rings and with at least two phenolic hydroxyl groups and/or (a2) condensed phenols, containing ether groups, with at least two aromatic rings and at least one phenolic hydroxyl group (a3) secondary amines with at least one hydroxyalkyl group, possible in a mixture with (a4) secondary dialkylamines or dialkoxyalkylamines without free hydroxyl groups, (a5) formaldehyde or compounds splitting off formaldehyde, with (b) epoxide resins, aliphatic hydroxyl groups from (a) and/or (b) being converted at least in part into urethane groups possibly by reaction with partly blocked isocyanates, containing furthermore fine-particulates non-ionic plastics in dispersed form. The dispersion and/or the fine-particulate plastics furthermore may contain pigments and/or fillers. The dispersion is suitable as an electro-dip means for coating on electrically conducting substrates acting as the cathodes in an electro-dip enameling process.
Patent AU-641672-B2 (AU)
Title: Detergent additive granulate and detergent
Inventor: FALHOLT PER
IPC: C11D17/00
Filed: 1990-06-14
Granted: 1993-09-30
Abstract: The detergent additive granulate is a cogranulate containing at least one enzyme and at least one photobleaching agent. If a detergent, a component of which is such detergent additive granulate, is used for laundering, the photobleaching agent will not tend to adhere selectively to the laundry during the initial washing process.
Patent AU-581140-B2 (AU)
Title: Shampoo compositions
Inventor: OH YOUNG SIK
IPC: C11D1/65
Filed: 1986-07-10
Granted: 1989-02-09
Abstract: Shampoos are disclosed which comprise a synthetic anionic surfactant, a dispersed, insoluble, non-volatile silicone, a tri long chain alkyl quaternary ammonium salt or a tri long chain amine, a suspending agent and water.