baber/WOPTO huggingface dataset:
Patent CA-3034758-A1 (CA)
Inventor: BURN JOHN
IPC: C12Q1/68
Filed: 2017-08-23
Abstract: The present invention relates to methods and kits for identifying microsatellite instability (MSI) in a sample. In particular it relates to identifying microsatellite instability in a tumor sample, which may be from a subject suspected of having colorectal cancer or Lynch syndrome. The methods and kits can be used to identify mismatch repair defects. More particularly the invention relates to a panel of markers for a sequencing based MSI test, that can differentiate between MSI-H and MSS CRCs. The invention also allows for determination of biological significance, differentiating between PCR and sequencing errors and MSI induced indels/mutations.
Patent CA-3035113-A1 (CA)
Inventor: SIMON MICHAEL J
IPC: H04L5/00
Filed: 2017-08-23
Abstract: Apparatuses and methods are provided for generating, transmitting, receiving, and decoding one or more band segmented bootstrap signals and one or more corresponding partitioned post bootstrap signals. For example, a transmitter is configured to generate a first set of symbols and a second set of symbols, where the first set of symbols includes information about the second set of symbols. The transmitter is further configured to generate a third set of symbols and a fourth set of symbols, where the third set of symbols includes information about the fourth set of symbols. The transmitter is also configured to generate a data frame including the first, second, third, and fourth set of symbols. A bandwidth of the data frame includes a first segment and a second segment.
Patent CA-3037634-A1 (CA)
Title: Static virtual camera positioning
Inventor: GLINER VADIM
IPC: G06T15/06
Filed: 2019-03-22
Abstract: Methods, apparatus and computer program products implement embodiments of the present invention that include receiving 3D image data with respect to a 3D region in a living body, the 3D region including a first body cavity having an opening to a second body cavity, and receiving coordinates of a seed location within the first cavity in proximity to the opening. The 3D image data is processed so as to identify, for each ray among a plurality of rays emanating from the seed location at different, respective angles, a respective distance from the seed location to a respective intersection point at which the ray intersects surface tissue in the second cavity. Among the rays, the ray for which the distance from the seed location to the respective intersection point is greatest is selected, and an image is rendered that includes the opening as seen from a location on the selected ray.
Patent CA-3037792-A1 (CA)
Title: Methode de remplissage automatise d'un bac avec des objets au moyen d'une main robotisee
Inventor: GROSBOIS JEROME
IPC: B65B5/12
Filed: 2017-09-18
Abstract: In order to carry out the automated filling of a bin with objects by means of a robot hand, at least one digital image of the empty bin is acquired, the compliance of the bin is automatically verified using the at least one digital image of the bin, and if the bin is compliant, the bin-filling method is performed by the robot hand, and if not, the bin is replaced with a new bin; and/or the following succession of steps is carried out in an automatic and repeated manner: (a) an object is positioned in the bin by means of the robot hand, in a position defined by a bin-filling plan; (b) at least one digital image of the bin containing at least one object is acquired; (c) it is automatically verified, in the at least one digital image obtained in the previous step, whether the object positioned in step (a) is correctly positioned; if it is, the subsequent step is carried out, and if not, the badly positioned object is removed by the robot hand and the method is repeated at step (a) with the same object.
Patent CA-3038275-A1 (CA)
Title: Procede de genotypage d'antigene leucocytaire humain et determination de la diversite d'haplotype de hla dans une population d'echantillons
Inventor: WANG CHUNLIN
IPC: C12Q1/68
Filed: 2017-09-26
Abstract: L'invention concerne un procédé de détermination de l'association des allèles de l'antigène leucocytaire humain (HLA) au niveau de loci adjacents dans l'ADN génomique à partir d'un échantillon biologique obtenu sur un sujet humain. La présente invention concerne également un procédé et un système de validation de l'exactitude d'une affectation d'un variant allélique à un locus génétique d'antigène leucocytaire humain (HLA).
Patent CA-3038661-A1 (CA)
Inventor: APTE ZACHARY
IPC: G06G7/58
Filed: 2017-09-27
Abstract: Embodiments of a method and system for improved microbiome sequencing can include: generating guide RNA complexes for a set of targets corresponding to a set of taxa associated with the microorganism-related condition; processing the biological sample with the gRNA complexes to generate microorganism nucleic acid fragments comprising a set of end regions associated with the set of targets; ligating the set of end regions with a set of adapters sharing an adapter sequence; and amplifying the set of targets based on the ligated set of end regions and a set of primers sharing a primer sequence associated with the adapter sequence.
Patent CA-3039668-A1 (CA)
Inventor: CENCER ROBERT J
IPC: B60P3/075
Filed: 2017-10-30
Abstract: Selon certains modes de réalisation, l'invention concerne un système de retenue de roue comprenant une piste à cale accouplée à un transport de véhicule, un mandrin d'ancrage, un mandrin à cliquet et une sangle. Le mandrin d'ancrage est accouplé à la piste à cale sur un premier côté d'un pneu de véhicule et comprend une paire de guides de sangle. La distance entre la paire de guides de sangle est plus large que la sangle. Le mandrin à cliquet est accouplé à la piste à cale sur un second côté du pneu. Le mandrin à cliquet comprend un cliquet permettant d'appliquer une force de rotation et une fente permettant de recevoir la sangle. La fente est plus large que la sangle. Une extrémité de la sangle est accouplée au mandrin d'ancrage et l'autre extrémité est insérée dans la fente de mandrin à cliquet. L'application d'une force de rotation au mandrin à cliquet produit une force de serrage qui serre la sangle autour d'une partie du pneu du véhicule.
Patent CA-3043463-A1 (CA)
Title: Measurement system and method of an industrial robot
Inventor: ASPLUND LARS
IPC: B25J9/00
Filed: 2017-11-17
Abstract: A measuring system of an industrial robot (2) comprises a plurality of moveable arms including a tool holder (10) and a 3D camera (1) carried by the industrial robot. The measuring system further comprises a mirror (3) for creating a mirror object (12i) of a real object (12). The 3D camera is fixed to one of the moveable arms (7) for measurement of the mirror object (12i).
Patent CA-3045168-A1 (CA)
Inventor: PFEFFER JOACHIM GEORG
IPC: A61M60/808
Filed: 2008-08-27
Abstract: The catheter device comprises a motor located at the proximal end of the catheter device, and a drive shaft which extends from the proximal end area of the catheter device to the distal end area and which drives a rotary element located at the distal end of the catheter device. The catheter device further comprises a tubular catheter shaft which encloses the drive shaft and which extends from the proximal end area to the distal end area of the catheter device. The drive shaft is connected to the motor at the proximal end of the catheter device by means of a coupling. The coupling is a magnetic coupling with a proximal magnet unit and a distal magnet unit. The proximal magnet unit is connected to the motor, and the distal magnet unit is connected to the drive shaft. The distal magnet unit is mounted in a coupling housing in a leaktight manner. The proximal end of the catheter shaft is connected to the coupling housing in a leaktight manner.
Patent CA-3047265-A1 (CA)
Title: Composition de traitement de la peau emballee et procede
Inventor: FONTANET OSVALDO
IPC: A45D34/00
Filed: 2017-12-05
Abstract: L'invention concerne une composition de traitement de la peau emballée comprenant : (a) un réceptacle avec un goulot et dans lequel est stockée une composition de traitement contenant des structures sphériques tridimensionnelles microscopiques comportant des parois extérieures membraneuses et des espaces intérieurs isolés, (b) un élément d'essuyage fixé à l'intérieur du goulot et comportant une partie cylindrique intérieure, (c) une fermeture pour le réceptacle, (d) un applicateur constitué d'une tige comportant une extrémité proximale fixée à la fermeture et une extrémité distale se terminant par une partie élargie. Lorsque la tige est extraite du réceptacle, la composition de traitement adhère à l'applicateur en une quantité suffisante pour permettre l'application de la composition de traitement contenant les structures sphériques microscopiques à la surface de traitement.
Patent CA-3047534-A1 (CA)
Inventor: DROZ PIERRE-YVES
IPC: G01S7/481
Filed: 2017-12-13
Abstract: Selon un exemple, cette invention concerne un dispositif LIDAR, comprenant une source de lumière qui émet de la lumière et une lentille de transmission qui dirige la lumière émise de sorte à éclairer une région d'un environnement avec un champ de vision défini par la lentille de transmission. Le dispositif LIDAR comprend en outre une lentille de réception qui focalise au moins une partie de la lumière entrante se propageant à partir de la région éclairée de l'environnement le long d'un trajet optique prédéfini. Le dispositif LIDAR comprend en outre un réseau de détecteurs de lumière positionnés le long du trajet optique prédéfini. Le dispositif LIDAR comprend en outre un détecteur de lumière décalée positionné à l'extérieur du trajet optique prédéfini. Le dispositif LIDAR comprend en outre un dispositif de commande qui détermine si des données de capteur collectées provenant du réseau de détecteurs de lumière comprennent des données associées à une autre source de lumière différente de la source de lumière du dispositif sur la base d'une sortie provenant du détecteur de lumière décalée.
Patent CA-3047947-A1 (CA)
Inventor: DE KOCK WERNER RUDOLPH
IPC: B01D29/66
Filed: 2019-06-25
Abstract: This invention relates to a particle extractor assembly 10, 100 which is used to extract and collect dust and/or other airborne pollutants from a workface. The assembly 100 is mobile as is mounted to a base 12 which includes a first platform 12.1 and a second pivotal platform 12.2 which is articulated to the first platform 12.1 and is configured to be pivotally displaced relative to the first platform between a lowered position and a discharge position in which it is inclined with respect to the first platform 12.1. The assembly also includes a vacuum pump 150 powered by an electrical motor 160, a particle filter 200 to filter out particles upstream of the vacuum pump and a drum arrangement which includes a collector drum 170 configured to rotate about an axis to mix its contents to form a slurry and it discharge the contents when in the discharge position.
Patent CA-3048500-A1 (CA)
Inventor: BRANDT BARON C
IPC: A41C3/00
Filed: 2018-02-23
Abstract: Aspects herein provide for a support garment (100) having a vibration damping structure (105) that is positioned between the breast contacting surfaces (110, 111) of the support garment. The vibration damping structure has a shape and/or material characteristics that enable it to substantially fill the space defined by a medial aspect of the wearer's breasts and the wearer's sternum. This positioning and placement facilitate the damping structure's ability to absorb and dissipate impact forces generated at least through the medial-to-lateral movement of the wearer's breasts during, for example, athletic activities.
Patent CA-3049447-A1 (CA)
Title: Pansement de fermeture abdominale multicouche a capacites d'instillation
Inventor: MERCER DAVID RICHARD
IPC: A61F13/00
Filed: 2018-01-23
Abstract: L'invention concerne un système de traitement permettant d'appliquer une thérapie par pression négative et un traitement d'instillation de fluide à un site tissulaire, en particulier un site de tissu abdominal. Dans certains modes de réalisation, le système de traitement peut comprendre un élément de pansement, une pluralité de voies d'élimination de fluide, une matrice d'instillation de fluide, un champ, une source de pression négative et une source d'instillation de fluide. Un fluide d'instillation peut être administré depuis la source d'instillation de fluide vers le site tissulaire par l'intermédiaire de la matrice d'instillation de fluide, et une pression négative peut être communiquée et un fluide retiré du site tissulaire par le biais de la pluralité de voies d'élimination de fluide.
Patent CA-3049947-A1 (CA)
Title: Control system for work vehicle, method, and work vehicle
Inventor: ISHIBASHI EIJI
IPC: E02F3/85
Filed: 2018-05-09
Abstract: This control system for a working vehicle is provided with a controller. The controller is programmed to perform the following process. The controller controls a working machine according to a prescribed target value. The controller determines a slip occurrence of a driving device during controlling of the working machine. The controller changes the target value in response to the slip determination result.
Patent CA-3051151-A1 (CA)
Title: Apparatus and method of connecting tubulars
Inventor: RUEHMANN RAINER
IPC: E21B19/16
Filed: 2018-02-01
Abstract: The present disclosure generally relates to a method for making up a tubular joint. The method includes rotating a first tubular relative to a second tubular to engage the first and second tubulars while measuring a torque between the first and second tubulars, calculating a set point of a relative rotational speed between the first and second tubulars using the measured torque, and using the calculated set point with a closed-loop controller to control the relative rotational speed between the first and second tubulars.
Patent CA-3051401-A1 (CA)
Title: Accessing spinal network to enable respiratory function
Inventor: LU DANIEL C
IPC: A61N1/372
Filed: 2018-01-24
Abstract: In various embodiments, methods are provided for improving, and/or regulating, and/or restoring respiration in a subject with a respiratory deficiency. In certain embodiments the methods involve neuromodulating the cervical spinal cord of a subject by administering transcutaneous stimulation to the cervical spinal cord or a region thereof at a frequency and intensity sufficient to regulate and/or to restore respiration; and/or neuromodulating the cervical spinal cord of a subject by administering epidural stimulation to the cervical spinal cord or a region thereof at a frequency and intensity sufficient to regulate and/or to restore respiration; and/or neuromodulating the cervical spinal cord of a subject with a magnetic stimulator at a frequency and intensity sufficient to regulate and/or to restore respiration.
Patent CA-3051419-A1 (CA)
Title: Activators of the retinoic acid inducible gene "rig-i" pathway and methods of use thereof
Inventor: BEDARD KRISTIN
IPC: A61P35/00
Filed: 2019-08-08
Abstract: The present invention is directed to compounds of Formula (I), which are activators of the RIG-I pathway. (see formula I)
Patent CA-3055043-A1 (CA)
Inventor: BERGHAMMER JOHN
IPC: B29C70/24
Filed: 2019-09-11
Abstract: A fiber material assembly has a base fiber material disposed at least partly behind a oxidized polyacrylonitrile (PAN) fiber material that is secured to at least one side of the base fiber base material. The fiber material assembly provides a high thermal resistance via a low area weight usage of oxidized PAN fibers which overlie a base fiber material.  The fiber material assembly can be provided such that the oxidized PAN fiber material provides either full or localized coverage, on one side or both sides, of the underlying base fiber material. The fiber material assembly provides the functionality of an acoustic heat shield or structural part with high thermal capacity.
Patent CA-3059172-A1 (CA)
Inventor: ALIZOTI NERITAN
IPC: A61M16/20
Filed: 2014-03-14
Abstract: Il est décrit un boîtier dadaptateur qui comprend un orifice dentrée définissant une voie de passage et un orifice de sortie en communication fluidique avec ledit orifice d'entrée sous forme dun passage. Une fin de débit dadministration de médicament est fournie dans le passage. Le boîtier dadaptateur comprend également une soupape pouvant passer en une position qui ferme lorifice dadministration de médicament et une position dans laquelle lorifice dadministration de médicament est ouvert. Un actionneur positionné en amont de la soupape, ainsi que couplé à cette dernière, comprend une partie dextrémité définissant une partie dextrémité définissant un canal central adapté pour être reçu dans une embouchure dun aérosol-doseur pressurisé. Il est également décrit un procédé dutilisation dun aérosol-doseur pressurisé ayant un tel boîtier dadaptateur.
Patent CA-3059235-A1 (CA)
Title: Integrated circuit interface and method of making the same
Inventor: HATHAWAY AARON ASHLEY
IPC: G01R1/04
Filed: 2018-05-04
Abstract: One example includes a device (100) that is comprised of a plurality of printed circuit boards (200), a plurality of vias (110), and a plurality of castellations (130). The plurality of printed circuit boards (200) are laminated together, at least some of the plurality of printed circuit boards (200) including a dielectric panel (210) and a plurality of conductor pads (220). The plurality of vias (110), through the plurality of conductor pads (220), include a conductive material to respectively electrically couple the plurality of conductor pads (220) with each other. The plurality of castellations (130), on at least one side of the plurality of printed circuit boards (200), to electrically couple each of a plurality of contact pins of an integrated circuit socket with respective contact pads of the plurality of conductor pads (220).
Patent CA-3060409-A1 (CA)
Title: Trem2 antigen binding proteins and uses thereof
Inventor: FOLTZ IAN
IPC: C07K16/28
Filed: 2018-04-20
Abstract: The present invention relates to antigen binding proteins, such as monoclonal antibodies, that specifically bind to and activate human triggering receptor expressed on myeloid cells-2 (TREM2) and pharmaceutical compositions comprising such antigen binding proteins. The agonist antigen binding proteins (e.g. antibodies) of the invention are capable of activating TREM2/DAP12 signaling in myeloid cells in the absence of Fc-mediated cross-linking of the antigen binding proteins. Methods of treating or preventing conditions associated with TREM2 loss of function, such as Alzheimer's disease and multiple sclerosis, using the antigen binding proteins are also described.
Patent CA-3061278-A1 (CA)
Inventor: GODEAUX OLIVIER
IPC: A61K39/12
Filed: 2018-05-15
Abstract: Compositions, vaccines and methods using adenovirus vectors for inducing protective immunity against a respiratory syncytial virus (RSV) infection are described.
Patent CA-3063898-A1 (CA)
Title: Ultra-thin, flexible thin-film filters with spatially or temporally varying optical properties and methods of making the same
Inventor: BANAEI ESMAEIL
IPC: G02B5/20
Filed: 2018-05-16
Abstract: A method of making an optical filter film with varying optical properties includes the step of drawing a multilayer polymeric preform into an optical filter and varying at least one environmental condition being a member of the group including of heat, pressure, tension, and a drawing speed, the at least one environmental condition being varied over time or over a distance, or both, and causing a variation in layer thickness within the optical filter. The preform may be drawn through a furnace subjecting the preform to a heating power that varies across a width of the furnace or over time or both across the width and over time. The preform may also be drawn through the furnace while the drawing speed varies across a width of the furnace or over time or both across the width and over time.
Patent CA-3066608-A1 (CA)
Title: Gas-insulated switchgear with vertically stacked interrupters
Inventor: YANNIELLO ROBERT
IPC: H02B13/035
Filed: 2018-05-03
Abstract: An apparatus includes a housing, at least one first gas-insulated circuit interrupter in the housing and at least one second gas-insulated circuit interrupter disposed in the housing above the at least one first gas-insulated circuit interrupter. The at least one first gas-insulated circuit interrupter and the at least one second gas-insulated circuit interrupter may be housed in respective ones of a first gas containment compartment and a second gas containment compartment vertically arranged in the housing. At least one first bus may be coupled to the at least one first gas-insulated circuit interrupter and at least one second bus may be coupled to the at least one second gas-insulated circuit interrupter. The buses may be disposed between the first and second gas-insulated circuit interrupters.
Patent CA-3069519-A1 (CA)
Inventor: BHOUMIK ANINDITA
IPC: C12N5/071
Filed: 2018-07-11
Abstract: Disclosed herein are universal donor stem cells and cells derived therefrom and related methods of their use and production. The universal donor stem cells disclosed herein are useful for overcoming allogeneic immune rejection in cell-based transplantation therapies. In certain embodiments, the universal donor cells disclosed herein are pancreatic endoderm cells that do not express one or more MHC-Class I cell-surface proteins and whose expression of at least one NK activating ligand is disrupted or inhibited.
Patent CA-3069930-A1 (CA)
Inventor: KLEY NIKOLAI
IPC: C07K14/555
Filed: 2018-08-08
Abstract: The present invention relates, in part, to agents that bind CD8 and their use as therapeutic and diagnostic agents. The present invention further relates to pharmaceutical compositions comprising the CD8 binding agents and their use in the treatment of various diseases, including, for example, cancers.
Patent CA-3070299-A1 (CA)
Title: Oncolytic viral vectors and uses thereof
Inventor: FINER MITCHELL H
IPC: C12N9/22
Filed: 2018-07-26
Abstract: The present disclosure relates to recombinant viral vectors for the treatment and prevention of cancer. Oncolytic viral vectors incorporate one or more of the following features: viral replication restriction by insertion of microRNA (miRNA) target sequences into the viral genome; disruption of oncogenic miRNA function; cancer microenvironment remodeling; and cancer cell target-ing by incorporation of protease-activated antibodies into the viral particle.
Patent CA-3071014-A1 (CA)
Inventor: GIESING DENNIS
IPC: A61M31/00
Filed: 2018-07-25
Abstract: The present invention provides methods for treating or suppressing tumor metastasis at a site distinct from the bladder in an individual having a urothelial carcinoma of lower tract, comprising locally delivering to the bladder an effective amount of a chemotherapeutic agent (such as gemcitabine), wherein the chemotherapeutic agent is delivered continuously to the bladder for a sustained period of time (such as at least 24 hours).
Patent CA-3071234-A1 (CA)
Title: Anti-cd147 antibody
Inventor: FUKUCHI KEISUKE
IPC: A61K39/395
Filed: 2018-07-26
Abstract: The present invention addresses the problem of providing a novel anti-CD147 antibody having exceptional anti-tumor activity and exceptional safety. The present invention also addresses the problem of providing a medicine containing such an antibody. The present invention also addresses the problem of providing, inter alia, a method for treating tumors in which the antibody or medicine is used. The present invention provides a CD147-specific antibody that activates CD147 and demonstrates a strong anti-tumor effect. The present invention provides an anti-CD147 antibody that demonstrates a strong anti-tumor effect independent of effector function. The present invention provides a pharmaceutical composition that contains such an anti-CD147 antibody. The present invention provides a method for treating tumors in which such an anti-CD147 antibody and/or pharmaceutical composition is used.