baber/WOPTO huggingface dataset:
Patent DE-69302220-T2 (DE)
Inventor: BUENDIA JEAN
IPC: A61K31/57
Filed: 1993-06-10
Granted: 1996-10-24
Abstract: The invention relates to a new process for preparing the compounds of formula (I): <IMAGE> in which the rings A and B represent a 3-keto- DELTA <4>-6-R3, optionally in a form protected in position 3, or 3-keto- DELTA <1,4>-6-R3, R is methyl or -CH2OR' where R' is hydrogen or an ether or ester residue, R1 and R2 form a  beta  epoxide, a second bond, or R1 is hydrogen, ketone, or hydroxy in  alpha  or  beta , optionally in etherified or esterified form, and R2 is hydrogen, or R1 is hydrogen and R2 is  alpha -hydroxy, or R1 is  beta -hydroxy optionally etherified or esterified and R2 is a fluorine or a bromine in  alpha , and R3 is hydrogen, fluorine or methyl in  alpha  or beta , according to which a  DELTA <16(17)> derivative is treated with a methylating agent, followed by intermediate hydrolysis and the enol thus obtained is oxidised by molecular oxygen in the presence of an appropriate reducing agent. The compounds (I) are known anti-inflammatory agents or possible precursors.
Patent DE-69308212-T2 (DE)
Inventor: KIRSTEIN DORTE
IPC: A61K31/47
Filed: 1993-08-05
Granted: 1997-09-18
Abstract: PCT No. PCT/DK93/00254 Sec. 371 Date Jan. 3, 1995 Sec. 102(e) Date Jan. 3, 1995 PCT Filed Aug. 5, 1993 PCT Pub. No. WO94/02338 PCT Pub. Date Feb. 17, 1994The present invention relates to hitherto unknown compounds of formula; Y stands for -CH=CH-; R1 is hydrogen or halogen, preferably fluorine, chlorine or bromine; R2 is halogen, preferably fluorine, chlorine or bromine, CH3, OCH3, NO2 or CF3, and n=0-3, preferably 0, 1 or 2; A stands for an acidic group, e.g. carboxy, 1-H-tetrazolyl or a hydroxamic acid group. The present compounds are of value in the human and veterinary practice as lipoxygenase inhibitors and/or leukotriene antagonists.
Patent DE-69309453-T2 (DE)
Inventor: BOFFITO CLAUDIO
IPC: H01M10/50
Filed: 1993-10-11
Granted: 1997-07-10
Abstract: A thermally insulating jacket under reversible vacuum, having an inner wall (2), an outer wall (3) and an inner space (4) between said walls in fluid communication with an outer housing (6; 6'; K) containing a reversible non-evaporable hydrogen getter (7; 7') loaded with hydrogen before use, wherein:   a) said reversible hydrogen getter (7; 7') has a hydrogen equilibrium pressure (Px1) lower than 100 mbar at 500 DEG C, when the hydrogen concentration in the getter is 0.1% b.w., and is kept at a variable or constant temperature (Ti) essentially different from the temperature (Tc) of the hotter wall of the jacket; b) said inner space (4) contains a non-evaporable promoter getter (9;9';9'') having a hydrogen equilibrium pressure (Px2) higher than 100 mbar at 500 DEG C, when the hydrogen concentrationin the getter is 0.1% b.w., which is essentially exposed to said temperature (Tc).   <IMAGE>
Patent DE-69310014-T2 (DE)
Inventor: DESAI NARENDRA RAGHUNATHJI
IPC: A61N5/06
Filed: 1993-02-05
Granted: 1997-11-06
Abstract: Liposomal pharmaceutical fomulations incorporating porphyrin photosensitizers useful for photodynamic therapy or diagnosis of malignant cells. The liposomal formulations comprise a porphyrin photosensitizer, particularly the hydro-mono benzoporphyrins (BPD) having light absorption maxima in the range off 670-780 nanometers, a disaccharide or polysaccharide and one or more phospholipids.
Patent DE-69323821-T2 (DE)
Inventor: BELLY ROBERT T
IPC: G01N33/543
Filed: 1993-08-26
Granted: 1999-08-19
Abstract: The present invention provides a novel dry analytical element for determination of an analyte in a fluid sample in thin film immunoassay, particularly chemiluminescence, fluorescence and colorimetry immunoassay. There is provided an analytical element comprising a support member, a reagent matrix comprised of at least one layer of a porous material carried on the support member, the matrix including a read area, an absorbent material in contact with the matrix, and light absorbing or reflecting means integral to the absorbent material and/or positioned between the absorbent material and the read area for absorbing or blocking background signal generated by washed, removed label and other interferents from outside the read area prior to it moving back into the read area. The analytical element can comprise a cover depending on the type of immunoassay to be conducted. <IMAGE>
Patent DE-69324777-T2 (DE)
Inventor: HSU CHEN-JUNG
IPC: G01N33/68
Filed: 1993-12-01
Granted: 1999-12-02
Abstract: A method (I) of selectively separating high density lipoprotein (HDL) from a blood sample contg. HDL, low DL and very low DL and chylomicrons comprises contacting the sample with finely divided particulate, porous silica or silicate having a particle size of LU-1000 microns in the longest dimension and surface pores of 80-1000 Angstroms in size as absorbent particles to form a complex between the silica or silicate and the HDL and separating the complex from the blood sample by solid/liquid separatory techniques, to provide a blood sample substantially free of HDL. In (I) the absorbent particles are pref. 2-500 microns in their longest dimension and the pores are 300-500 Angstrom in size. The absorbent material is pref. silica, silica gel or controlled pore glass. The second reagent system comprises a polyanion, e.g. heparin or dextran sulphate and a cation is Mn2+ or Mg2+.
Patent DE-69327337-T2 (DE)
Inventor: FAHS RICHARD W II
IPC: A01K63/00
Filed: 1993-09-20
Granted: 2000-07-27
Abstract: The present invention is directed to apparatus and a method for maintaining and growing a primary cultured species and secondary organisms essential to the growth of the primary species in an aquaculture system in which the parameters which affect the maintenance and growth of the primary cultured species are carefully monitored and adjusted on a substantially continuous basis. The apparatus comprises a tank for holding an aqueous medium and the primary species, nutrient supply equipment, equipment for selectively removing the aqueous medium from the tank, apparatus for removing particulate matter from the aqueous medium removed from the tank, a sterilizer for sterilizing the aqueous medium removed from the tank, equipment for removing toxins from the aqueous medium removed from the tank without biological filtration, and a station with associated equipment for bringing the aqueous medium to a steady state suitable for the growth and survival of the primary species. Conduits, pumps and associated valving are provided for transferring the aqueous medium among the various treatment stations and for returning the aqueous medium to the tank after it has been treated by any or all of the foregoing treatment equipment.
Patent DE-69330215-T2 (DE)
Inventor: CHITTOFRATI ALBA
IPC: C08G65/00
Filed: 1993-02-16
Granted: 2002-04-18
Abstract: Polishes for metal surfaces, based on dispersions of waxes, fluorinated polymers and perfluoropolyoxyalkylene oils acquire high gloss characteristics combined with improved water-repellency and resistance to soiling of 0.1-5% by weight of at least a cationic emulsifier comprised in the general formula    (I)   R [ L-Q<+> X<-> ]t    where:   R =   a chain of perfluoropolyoxyalkylene units; L =   a divalent organic group; Q =   a polar group; X =   a halogen, or a group of formula    CH3-Phenylene-SO3-  R''SO3-     R'' =   F-(CF2)m-; t =   1 or 2; m =   1-4. The polishes containing the emulsifiers of formula (I) as well as the compounds comprised in said formula are claimed as new products.
Patent DE-69333575-T2 (DE)
Inventor: NAGLEY PHILLIP
IPC: A61K31/525
Filed: 1993-05-28
Granted: 2005-08-25
Abstract: PCT No. PCT/AU93/00251 Sec. 371 Date Mar. 20, 1995 Sec. 102(e) Date Mar. 20, 1995 PCT Filed May 28, 1993 PCT Pub. No. WO93/24650 PCT Pub. Date Dec. 9, 1993The present invention relates generally to therapeutic compositions comprising one or more redox compounds. The therapeutic compositions of the present invention are useful in enhancing cellular ATP production thereby ameliorating the effects of reduced bioenergy capacity such as occurring during aging, systemic or vascular disease or in conjunction with chemical therapy. The present invention therefore contemplates a method for enhancing cellular ATP production in an animal, said method comprising administering to said animal, an effective amount of a redox compound for a time and under conditions sufficient to increase or otherwise elevate the activity and/or operation of a cellular oxidoreductase system in cells of said animal.
Patent DE-69401024-T2 (DE)
Inventor: EMMER GERARD
IPC: B29C49/08
Filed: 1994-04-13
Granted: 1997-05-15
Abstract: The invention relates to the heat treatment of the body (2) of a preform (1) or of an intermediate container made of thermoplastic material during a process for manufacturing a container, such as a flask or a bottle, especially by blowing or drawing-blowing; the entire body (2) of the preform is heated to a temperature above the softening temperature of the material and at least one longitudinal portion (13) of the body (2) of the preform, rotating about itself, is at an even higher temperature than that of the rest (14) of the body, this enabling a final container with a body of complex shape to be obtained. <IMAGE>
Patent DE-69404031-T2 (DE)
Inventor: PICARD ANTOINE
IPC: B62D53/00
Filed: 1994-04-19
Granted: 1998-01-15
Abstract: PCT No. PCT/FR94/00440 Sec. 371 Date Nov. 29, 1995 Sec. 102(e) Date Nov. 29, 1995 PCT Filed Apr. 19, 1994 PCT Pub. No. WO94/23985 PCT Pub. Date Oct. 27, 1994The articulated vehicle is formed from a plurality of modules interconnected in an articulated fashion, including one leading module (1) with a front steering set of wheels (12), a rear module (3) with a controlled orientable rear set of wheels (13) and, optionally, one or more intermediate modules (2), a vehicle wherein two successive modules are connected by a movable articulation support (6, 7) carried by an axle and duplicated by a rigid oblique articulated connection (8,9), the orientation of each movable articulation support (6, 7) and that of the rear orientable wheel set (13) being controlled in such a way that its transverse median axis corresponds at all times to the bisector of the angle formed by two successive modules.
Patent DE-69413199-T2 (DE)
Inventor: COOPER DAVID
IPC: B01J29/08
Filed: 1994-07-20
Granted: 1999-02-04
Abstract: Ammonium zeolites of extremely low alkali metal content are prepared by a process of potassium ion exchange followed by ammonium ion exchange. Zeolite X or zeolite Y that contain a significant amount of sodium are contacted with a potassium salt solution under conditions that provide a substantial exchange of potassium for sodium. The potassium enriched zeolite is then contacted with an ammonium salt solution so that the ammonium ion replaces the sodium and potassium ions. The resulting ammonium zeolite X or Y contains considerably less than 1% alkali metal calculated as Na2O.
Patent DE-69413971-T2 (DE)
Inventor: VIRVING NILS
IPC: D21D1/38
Filed: 1994-05-02
Granted: 1999-03-11
Abstract: Refiner segments for use in disk refiners for the disintegration of lignocellulose-containing material are disclosed, in which the refiner segment is formed with a pattern of bars and grooves and includes dams placed in the grooves. The dams are arranged so that their angle in relation to the radius of the refiner segment is less than about 30 DEG , preferably less than about 15 DEG .
Patent DE-69427343-T2 (DE)
Inventor: TORII SHIGERU
IPC: B01J31/12
Filed: 1994-11-04
Granted: 2002-04-25
Abstract: A process for producing a 3-substituted cephem compound from an allenyl- beta -lactam compound which can readily be prepared from an inexpensive penicillin compound in a short reaction path. The process comprises reacting an allenyl- beta -lactam compound with an organohalogen compound in the presence of an at least equimolar amount of a metal having a standard oxidation-reduction potential of -0.3 V/SCE or less and 0.0001 - 0.5 mol, per mole of the lactam, of a metallic compound having a standard oxidation-reduction potential higher than that of the above metal.
Patent DE-69427763-T2 (DE)
Inventor: NUSSER DENNIS W
IPC: G06F3/02
Filed: 1994-08-31
Granted: 2002-05-23
Abstract: Input apparatus scaled for non-adult humans and adult humans having small hands. The input apparatus are especially well suited for use as computer keyboards for use by schoolchildren. Also disclosed is a computing system including the input apparatus.
Patent DE-69428523-T2 (DE)
Inventor: DANTE LEE G
IPC: A61K31/495
Filed: 1994-02-28
Granted: 2002-06-06
Abstract: A new composition and method of treating depression includes administering to a depressed patient a pharmacologically effective dose of naloxone or naltrexone or their pharmacologically effective salts and esters in combination with at least one nontricyclic serotonin reuptake inhibitor antidepressant or their pharmacologically effective salts and esters. The patient may while undergoing antidepressant therapy be undergoing treatment with a benzodiazepine for anxiety.
Patent DE-69500996-T2 (DE)
Inventor: ROBINSON GRENVILLE
IPC: B01L3/00
Filed: 1995-03-09
Granted: 1998-03-05
Abstract: PCT No. PCT/GB95/00507 Sec. 371 Date Nov. 22, 1996 Sec. 102(e) Date Nov. 22, 1996 PCT Filed Mar. 9, 1995 PCT Pub. No. WO95/24632 PCT Pub. Date Sep. 14, 1995The use as a cuvette in spectrophotometric assays of a sample-collecting device is disclosed, the said device possessing a cavity or cavities each having a dimension small enough to enable sample liquid to be drawn into the cavity by capillary action, wherein a surface of the cavity is a surface of a transparent solid plate having a substantially rectangular cross section and forming a wall of the cavity, the opposite surface of the cavity being an additional structure having a substantially rectangular cross section and forming a wall of the cavity, and wherein a portion of said plate carries a reflective coating and a portion of said additional structure is reflective.
Patent DE-69515709-T2 (DE)
Inventor: IRINO SHIGEAKI
IPC: A23L27/30
Filed: 1995-01-16
Granted: 2001-02-01
Abstract: The invention relates to a process for the preparation of N-benzyloxycarbonyl- alpha -L-aspartyl-L-phenylalanine methyl ester by enzymatic coupling of N-benzyloxycarbonyl-L-aspartic acid and L-phenylalanine methyl ester in an aqueous medium with formation of a precipitate, the coupling reaction being effected with (virtually) equimolar quantities of N-benzyloxycarbonyl-L-aspartic acid and L-phenylalanine methyl ester under the influence of a neutral protease at an initial pH of from 4.5 to 6.0 and in the presence of from 3 to 25%, calculated as per cent by weight based on the total reaction mixture, of an alkali metal salt, alkaline earth metal salt or ammonium salt.
Patent DE-69523161-T2 (DE)
Inventor: ASGHARIAN BAHRAM
IPC: C11D3/02
Filed: 1995-07-17
Granted: 2002-06-13
Abstract: Saline solutions useful in treating contact lenses are described. Unlike prior saline solutions used for similar purposes, the present solutions do not contain conventional antimicrobial agents which are potentially toxic to ocular tissues. Rather, the solutions contain a combination of a borate-polyol complex, one or more anionic or nonionic surfactants, and a low molecular weight amino acid (e.g., glycine). It has been found that this combination effectively preserves the saline solutions from antimicrobial contamination, is relatively nontoxic to ocular tissues, and is compatible with oxidizing agents used in certain contact lens disinfecting systems. The combination also facilitates the cleaning of contact lenses.
Patent DE-69525305-T2 (DE)
Inventor: TSURIA YOSSI
IPC: H04N7/173
Filed: 1995-11-09
Granted: 2002-08-14
Abstract: A television receiver assembly including a multi-channel television signal decoder (12) coupled to a source of incoming television signals (15), a multi-channel television display (14) coupled to the decoder for displaying received decoded television signals, a channel changing device operative to change the channel decoded by the decoder and displayed by the display, the channel changing device being inoperative to display received decoded television signals during a channel changing interval, and an interval message provider (28) operative to display at least one predetermined information message during the channel changing interval. <IMAGE>
Patent DE-69528961-T2 (DE)
Inventor: CONTIERO CLAUDIO
IPC: H01L21/8234
Filed: 1995-03-09
Granted: 2003-09-04
Abstract: A process for the manufacturing of an integrated circuit comprising lateral DMOS-technology power devices and non-volatile memory cells provides for: forming respective laterally displaced isolated semiconductor regions (R1,R2,R6), electrically insulated from each other and from a common semiconductor substrate (1), inside which the devices will be formed; forming conductive insulated gate regions (33,34,37) for the lateral DMOS-technology power devices and for the memory cells over the respective isolated semiconductor regions (R1,R2,R6); inside the isolated semiconductor regions (R1,R2) for the lateral DMOS-technology power devices, forming deep body regions (25,26) aligned with edges of the insulated gate regions (33,34), and channel regions (29,30) extending under the insulated gate regions (33,34). The deep body regions (25,26) are formed by means of a first implantation of a first dopant in a direction substantially orthogonal to a top surface of the integrated circuit, performed with an energy and with a dopant dose such that the concentration of the first dopant has a peak located at a prescribed distance from the surface of the isolated semiconductor regions (R1,R2). The channel regions (29,30) are formed by means of a second implantation of a second dopant along directions tilted of a prescribed angle with respect to a direction orthogonal to a top surface of the integrated circuit, in a dose and with an energy such that said channel regions (29,30) are formed directly after the implantation of the second dopant without performing a thermal diffusion at a high temperature of the second dopant. <IMAGE>   <IMAGE>   <IMAGE>   <IMAGE>
Patent DE-69532760-T2 (DE)
Inventor: SANTIAGO NOEMI B
IPC: C07K5/06
Filed: 1995-10-16
Granted: 2004-08-05
Abstract: The present invention relates to compositions and methods for orally delivering antigens. The antigen and an adjuvant are combined with an acylated amino acid or polyamino acid and, a sulfonated amino acids or polyamino acid, or a salt of the foregoing.
Patent DE-69600253-T2 (DE)
Inventor: CORDI ALEX
IPC: A61P25/28
Filed: 1996-12-09
Granted: 1998-11-12
Abstract: 3-Hydroxy-4-imidazolidinone of formula (I) and its salts are new.   (I) is prepared by reacting glycine hydroxamic acid of formula (II) H2N-CH2-CO-NH-OH with an aqueous formaldehyde solution.
Patent DE-69620298-T2 (DE)
Inventor: BEST DAVID
IPC: C07D251/60
Filed: 1996-05-23
Granted: 2002-11-28
Abstract: A high-pressure, non-catalytic, process for producing melamine from urea wherein the melamine is recovered directly as a dry powder without washing or recrystallization is described. In the process, liquid melamine is fed to a cooling unit where it is quenched with liquid medium, preferably liquid ammonia. Increasing the pressure within the cooling unit to a pressure in excess of 41.4 bar (600 psi) and preferably to 82.7 to 96.5 bar (1200 to 1400 psi) provides melamine having a purity in excess of 99%.
Patent DE-69627507-T2 (DE)
Inventor: PERRY B
IPC: F02M61/16
Filed: 1996-08-02
Granted: 2003-11-06
Abstract: An abrasive liquid slurry for polishing and radiusing microholes comprises:     a liquid medium; finely divided abrasive particles, wherein the slurry is characterized in that the abrasive particles remain uniformly distributed when the slurry is not subjected to shear, and the slurry decreases in viscosity when subjected to shear flowing through a microhole at a pressure of 0.69 to 13.79 Mpa; and a rheological additive to maintain distribution of said particles.
Patent DE-69630727-T2 (DE)
Inventor: PARK KYOUNG-BAE
IPC: C08B37/08
Filed: 1996-03-08
Granted: 2004-09-30
Abstract: The present invention relates to the radioactive chitosan complex formed by labelling a chitosan, a biocompatible and biodegradable natural polymer, with radionuclide, a radioactive chitosan macroaggregate formed by making chitosan complex into particles, and a kit for preparing radioactive chitosan complex, process for preparation thereof and the use thereof for an internal radiation therapeutic agent. The radioactive chitosan complex and its macroaggregate can be used as an internal radiation therapy for rheumatoid arthritis or cystic cancer such as liver cancer, brain cancer, breast cancer, ovary cancer and the like by administering them directly to the lesion.
Patent DE-69707626-T2 (DE)
Inventor: VAN DEN BERG KAREL
IPC: A01J5/04
Filed: 1997-07-01
Granted: 2002-07-11
Abstract: The milking machine consists of a milk box (1) with a robot arm (3). The robot arm can move longitudinally on rails (5&6). Control cylinder (20) permits the robot arm to move sideways around pivot point (16). The milking robot that has automatically connecting teat cups (25) and a detector (26) which can determine the position of the animal's teats.
Patent DE-69709928-T2 (DE)
Inventor: TAGLIAFERRI MARCO
IPC: F23N5/12
Filed: 1997-10-17
Granted: 2002-08-29
Abstract: The combined gas-air control system for gas fired boilers (B) including a microcontroller ( mu C) with memory means, set point temperature selector means (Rh,Rs), measuring means (18,19,20,21), a thermostat (27), a variable-speed fan (6), a gas modulating valve (MV) in which the microcontroller ( mu C) comprises: first controlling means (22) for correcting the error signal E(T)=Trh-Th or E(T)=Trs-Ts and for controlling the air pressure in the combustion chamber (1), second controlling means (23) for correcting the error signal E(P)=Pac-Pa and for controlling the speed of the fan, processing means (24,25) for processing the ionisation voltage and the modulating valve current signals, third controlling means (26) for correcting the error signal E(V)=Vion(th)-Vion and the modulating valve current. <IMAGE>
Patent DE-69713772-T2 (DE)
Inventor: COFFINDAFFER WOODROW
IPC: A61Q5/12
Filed: 1997-03-18
Granted: 2003-02-27
Abstract: Disclosed are aqueous conditioning shampoo compositions comprising an anionic detersive surfactant component; an organic, cationic, hair conditioning polymer, and from about 0.01% to about 1.0% by weight of a water insoluble, synthetic ester having a viscosity of from about 1 to about 300 centipoise, and which conforms to either of the following formuls wherein R1 is an alkyl, alkenyl, hydroxyalkyl or hydroxyalkenyl group, having from 7 to 9 carbon atoms; n is a positive integer having a value of from 2 to 4; R2 is an alkyl, alkenyl, hydroxyalkyl or hydroxyalkenyl group, having from 8 to 10 carbon atoms; and Y is an alkyl, alkenyl, hydroxy or carboxy substituted alkyl or alkenyl, having from about 2 to about 20 carbon atoms; and an organic, water insoluble, conditioning oil having a viscosity of from about 1 to about 300 centipoise, selected from the group consisting of hydrocarbon oils, fatty esters other than the above synthetic esters, and combinations thereof. The organic conditioning oil is preferably a polyolefin. The shampoo compositions provide improved hair conditioning performance, and eliminates or minimizes the slimy, excessively conditioned, wet hair feel often associated with the use of a cationic hair conditioning polymers.