baber/WOPTO huggingface dataset:
Patent WO-2021178481-A1 (WO)
Inventor: DZURICKY MICHAEL
IPC: A61K47/69
Filed: 2021-03-03
Abstract: Described herein are protein nanopartides comprising a fusion protein comprising at least one binding polypeptide and at least one unstructured polypeptide, in one aspect, the nanopartides comprise a di-block of repeats of a core polypeptide, repeats of a corona polypeptide, and one or more binding proteins. The nanopartides can be used as therapeutic agents, targeted-delivery agents, separation agents, or purification agents.
Patent WO-2021178556-A1 (WO)
Inventor: YOUNG TARA
IPC: C12N15/113
Filed: 2021-03-03
Abstract: Provided herein are methods and compositions related to the treatment or prevention of cancer ( e.g , by targeting a tumor in a subject with cancer) by administering to a subject an agent that inhibits autophagy. In certain aspects, provided herein are methods of compositions related to methods of sensitizing cancer cells to tumor necrosis factor-alpha (TNF-α) mediated killing by contacting the cells or administering the agent that inhibits autophagy.
Patent WO-2021183350-A1 (WO)
Title: Method and apparatus for applying a material onto articles using a transfer component
Inventor: DONNER CHRISTOPHER
IPC: B65C3/14
Filed: 2021-03-04
Abstract: Apparatuses and methods for applying a transfer material onto one or more surfaces of an article are disclosed, including apparatuses and methods of transfer printing on and/or decorating three-dimensional articles, as well as the articles printed and/or decorated thereby. The apparatuses and methods may include providing a deposition device, such as a printing device; providing a transfer component; depositing a material onto a portion of the transfer component with the deposition device; modifying the portion of the transfer component with the transfer material thereon to conform the transfer component to at least a portion of one or more surfaces of the three-dimensional article; and transferring the transfer material onto the one or more surfaces of the article.
Patent WO-2021206835-A1 (WO)
Title: Minimally invasive tools, systems and methods
Inventor: ALSPAUGH JULIA
IPC: A61B17/00
Filed: 2021-03-08
Abstract: A system includes a first tool having a base, a nut, and a tool guide. The base extends from a first end to a second end and includes at least one thread disposed along a length thereof. The first end includes a foot having a widthwise dimension that is greater than a diameter of the at least one thread. The nut is configured to be disposed along the length of the base and to engage at least one thread. The tool guide is configured to be slideably disposed along the length of the base and has a body including a flange portion. The flange portion defines an opening for receiving at least one of a pin and a cutting tool. Rotation of the first nut causes the nut to translate along the length of the base thereby causing the tool guide to move along the length of the base.
Patent WO-2021188366-A1 (WO)
Title: Sustainable dispensing package having a telescopic actuator
Inventor: THULIN NATHANIEL
IPC: A45D34/00
Filed: 2021-03-12
Abstract: Described herein, dispensing packages for a spreadable personal care product and its respective methods for dispensing a spreadable personal care product. The dispensing package comprises a reusable dispenser, a replaceable cartridge and optionally a top cap. The reusable dispenser comprises a tubular body and a telescopic actuator. The telescopic actuator comprises a hand wheel, a leading screw, a tubular screw and an elevator. The replaceable cartridge comprises a push plate. The telescopic actuator is able to engage with the push plate of the replaceable cartridge to deliver the personal care product such that a top surface of the elevator telescopes with a bottom surface of the push plate of the replaceable cartridge. When the hand wheel is turned in a predetermined direction, the leading screw rotates and the top surface of the elevator advances upwardly, which advances the push plate upwardly and pushes the personal care product out towards an open top of the tubular body.
Patent WO-2021188552-A1 (WO)
Title: Supporting allocation modification during transition instance in an integrated access and backhaul network
Inventor: LUO JIANGHONG
IPC: H04L5/00
Filed: 2021-03-16
Abstract: Aspects presented herein may enable an IAB node to modify a resource allocation or change one or more parameters related to the resource allocation when the IAB node detects that the resource allocation overlaps with guard symbols or another resource allocation. In one aspect, an IAB node determines that a first channel allocation will be punctured based on an overlap of the first channel allocation with at least one of a guard symbol or a second channel allocation. The IAB node uses, for the first channel allocation or the second channel allocation, one or more of a modified parameter or a modified grant in response to determining that the first channel allocation will be punctured.
Patent WO-2021195445-A1 (WO)
Title: Compositions de fibroïne de soie hydrophobes et leurs procédés de fabrication
Inventor: KAPLAN DAVID
IPC: C08L89/00
Filed: 2021-03-25
Abstract: La présente divulgation concerne des compositions, des procédés de fabrication et des procédés d'utilisation d'une composition à base de soie modifiée ayant une hydrophobicité sélectivement réglable. Les compositions selon l'invention comprennent de la fibroïne de soie ayant un substituant haloalkyle. Le substituant haloalkyle est couplé à un acide aminé de la fibroïne de soie par l'intermédiaire d'un agent de liaison.
Patent WO-2021207137-A1 (WO)
Title: Crystalline 5-methoxy-n,n-diallyltryptamine compounds
Inventor: CHADEAYNE ANDREW R
IPC: A61K9/28
Filed: 2021-04-06
Abstract: The disclosure relates to 5-methoxy- N,N -diallyltryptamine ("5-MeO-DALT"), bis-(5-meth-oxy- N,N - di-allyl-tryptammonium) fumarate ("5-MeO-DALT fumarate"), and crystalline bis-(5-meth-oxy- N,N - di-allyl-tryptammonium) fumarate ("5-MeO-DALT fumarate"), compositions containing them, and the methods of treatment using them.
Patent WO-2021207364-A1 (WO)
Title: Expandable implant with worm gear
Inventor: BARRUS MICHAEL
IPC: A61F2/44
Filed: 2021-04-07
Abstract: An expandable device comprising, a body defining a bore, a shaft received in the bore of the body, an end plate coupled to the shaft, wherein rotation of the shaft translates the end plate with respect to the body, and a locking mechanism engaged with the shaft so as to permit the shaft to rotate in a first direction and apply a resistance force to resist the shaft when attempting to rotate in a second direction.
Patent WO-2021211588-A1 (WO)
Title: High-expansion foam generator having a manifold with linear headers arranged in an orthogonal configuration
Inventor: FEENSTRA SHAWN
IPC: A62C5/02
Filed: 2021-04-13
Abstract: An apparatus and method directed to aspirated-type high-expansion foam generation having a manifold with linear headers arranged in an orthogonal configuration. The generator has a nozzle manifold configured to receive a foam solution and at least one nozzle assembly. The generator can include a foam generator assembly disposed adjacent the nozzle manifold. The foam generator has a body portion having a first foam generating portion having a tapered configuration and a second foam generating portion having a tapered configuration with a base that is connected to an apex of the first foam generating portion. The foam generating assembly is configured such that the second foam generating portion protrudes into an interior of the first foam generating portion. The generator is configured such that a ratio of a largest inlet dimension of the foam generator assembly to a length of the foam generator assembly is 0.50 or less, and the generator includes at least one main header that is disposed orthogonal to at least one sub-header.
Patent WO-2021216651-A1 (WO)
Inventor: HU LIANGBING
IPC: C02F1/72
Filed: 2021-04-21
Abstract: An evaporative device has a piece of at least partially-delignified plant material. The at least partially-delignified plant material has a modified microstructure including a plurality of vessels, a plurality of fibers, and a plurality of engineered micropores. Each vessel can define a first lumen having a maximum cross-sectional dimension of at least 100 µm. Each fiber can define a second lumen having a maximum cross-sectional dimension less than or equal to 20 µm. The engineered micropores can extend through walls of the vessels or fibers so as to fluidically interconnect the first and second lumina. In some embodiments, the plant material is reed or bamboo.
Patent WO-2021222893-A1 (WO)
Inventor: PIORKOWSKI DANIEL THOMAS
IPC: C11D3/04
Filed: 2021-05-03
Abstract: A unit dose detergent pack is disclosed. The unit dose detergent pack includes a pouch formed from a water-soluble film and an opacified liquid detergent composition releasably disposed within the pouch. The opacified liquid detergent composition includes a plurality of neutralizing agents including more than 50 mole percent of sodium hydroxide and a remainder alkanolamine based on a total of 100 mole percent of the sodium hydroxide and the alkanolamine together. The composition further includes a fatty acid and water. A weight ratio of the sodium hydroxide and the fatty acid is from about 0.3:1 to about 0.8 to 1. The opacified liquid detergent composition is free of a microplastic opacifier and has a turbidity of at least 250 NTUs measured utilizing a turbidity meter at about 24°C. Also disclosed is an opacified liquid detergent composition and a method of making the same.
Patent WO-2021225983-A1 (WO)
Title: System and method to use suction to enhance permeabilization and transfection of cells
Inventor: LIN HAO
IPC: A61P31/14
Filed: 2021-05-03
Abstract: A method and apparatus for promoting the delivery of a molecule across a cell membrane comprises delivering a molecule to a delivery site of a region of tissue surrounding the cell membrane. A suction component applies a suction through a suction tip that surrounds the surface of the delivery site creating a seal to promote delivery of the molecule across the cell membrane. The application of the suction is controlled to create a predetermined negative pressure for a predetermined period of time before releasing the negative pressure. Suction is used to enhance permeabilization and transfection of cells. The technique can be used to enhance the uptake and subsequent transfection and expression of plasmid DNA vaccines, mRNA vaccines and other nucleic acid molecules, that are introduced subcutaneously. It can be used in combination with coated microneedles.
Patent WO-2021226546-A1 (WO)
Title: Protease inhibitors for treatment or prevention of coronavirus disease
Inventor: LIN MICHAEL Z
IPC: A61K39/215
Filed: 2021-05-07
Abstract: Provided are protease inhibitor compounds that find use in treating or preventing coronavirus disease. In some embodiments, the coronavirus disease is COVID-19. Also provided are compositions and kits comprising the compounds, as well methods of using the compounds to treat or prevent coronavirus disease. Methods of assessing inhibition of coronavirus protease activity by an agent are also provided.
Patent WO-2021243171-A1 (WO)
Inventor: KIERNAN BERNARD MATTHEW
IPC: A61K31/5513
Filed: 2021-05-28
Abstract: La présente invention concerne des moyens synthétiques pour la production de composés de dibenzodiazépinone de farnésyle, comprenant AMO -01.
Patent WO-2021247613-A1 (WO)
Inventor: GATYS LEON
IPC: A61B5/1455
Filed: 2021-06-01
Abstract: A wearable device can be used for hypertension monitoring. The wearable device can include a motion sensor and an optical sensor. The data from the sensors can be processed in the wearable device and/or by another device in communication with the wearable device to provide an early screening for undiagnosed hypertension. If the screening estimates undiagnosed hypertension for a user, the user can then be notified to seek a proper hypertension diagnosis. The hypertension monitoring can include a first stage to estimate one or more short-term hypertension scores or parameters. The hypertension monitoring can also include a second stage to estimate a long-term hypertension score using accumulated short-term scores/parameters to estimate hypertension.
Patent WO-2022132226-A1 (WO)
Title: Synthèse de pose de main 3d basée sur des réseaux génératifs guidés multimodales
Inventor: LIN SHIH-YAO
IPC: G06N3/04
Filed: 2021-06-25
Abstract: L'invention concerne des systèmes et des procédés permettant d'obtenir des images de main. Un procédé, mis en œuvre par au moins un processeur qui met en œuvre au moins un réseau, consiste à obtenir une image source unique, une pose de main tridimensionnelle (3D) d'une première main dans l'image source unique, et une pose de main cible 3D ; et à générer une image d'une seconde main, qui a un aspect de la première main et une pose de la pose de main cible 3D, sur la base de l'image source unique, de la pose de main 3D et de la pose de main cible 3D.
Patent WO-2022006435-A1 (WO)
Title: Adaptive apparatus for transporting and sewing material along arbitrary seam shapes
Inventor: BAKER MICHAEL
IPC: D05B39/00
Filed: 2021-07-01
Abstract: Various examples are provided related to transporting and sewing material in, e.g., automation of sewing robots. Multiple pieces of layered materials can be transported on a flat planar surface while maintaining the material layer's position and orientation relative to one another during a sewing procedure of these materials along any arbitrary seam shape. In one example, among others, a system includes a sewing machine including a sewing needle, a material holding assembly and a translation system. The material holding assembly can include mechanical fingers that can contact material on a sewing plane adjacent to the sewing needle and a structural grounding system supporting the mechanical fingers. The translation system can reposition the material on the sewing plane via the mechanical fingers. Clearance around the sewing needle can be provided by repositioning individual mechanical fingers around the sewing needle.
Patent WO-2022026455-A1 (WO)
Inventor: NORDMAN RICHARD
IPC: G01N21/05
Filed: 2021-07-27
Abstract: A flow cell and flow cell system which allows for calibration of an attached sensor to be performed in place. Specifically, the ability to utilize standard addition techniques of calibration without the need to take a test sample from the process stream or remove the sensor from operating on the flow cell.
Patent WO-2022031718-A1 (WO)
Title: Wireless device paging
Inventor: KIM TAEHUN
IPC: H04W72/04
Filed: 2021-08-03
Abstract: A wireless device receives, from a base station, a paging message indicating a configured uplink grant. The wireless device determines, based on the paging message indicating the configured uplink grant, timing information for transmission of an uplink packet. The wireless device transmits the uplink packet, to the base station, based on the timing information.
Patent WO-2022046418-A1 (WO)
Title: Memory array comprising strings of memory cells and method used in forming a memory array comprising strings of memory cells
Inventor: HOPKINS JOHN
IPC: H01L27/11568
Filed: 2021-08-11
Abstract: A method used in forming a memory array comprising strings of memory cells comprises forming a stack comprising vertically-alternating first tiers and second tiers. The stack comprises laterally-spaced memory-block regions that have horizontally-elongated trenches there-between. Channel openings extend through the first tiers and the second tiers in the memory-block regions. Channel material of channel-material strings is formed in the channel openings and the channel material is formed in the horizontally-elongated trenches. The channel material is removed from the horizontally-elongated trenches and the channel material of the channel-material strings is left in the channel openings. After removing the channel material from the horizontally-elongated trenches, intervening material is formed in the horizontally-elongated trenches laterally-between and longitudinally- along immediately-laterally-adjacent of the memory-block regions. Other embodiments, including structure independent of method, are disclosed.
Patent WO-2022047209-A1 (WO)
Inventor: LI ROGER
IPC: A61K39/00
Filed: 2021-08-27
Abstract: La présente invention concerne des méthodes de sélection d'un traitement et facultativement de traitement de sujets atteints d'un cancer de la vessie infiltrant le muscle basées sur les niveaux d'expression tumorale de chimiokines, de gènes cytotoxiques, et/ou de gènes de cellules dendritiques.
Patent WO-2022072415-A1 (WO)
Title: Privacy preserving machine learning using secure multi-party computation
Inventor: WANG GANG
IPC: G06F21/62
Filed: 2021-09-29
Abstract: This disclosure relates to a privacy preserving machine learning platform. In one aspect, a method includes receiving, by a first computing system of multiple multi-party computation (MPC) systems, an inference request that includes a first share of a given user profile. A number k of nearest neighbor user profiles that are considered most similar to the given user profile are identified. The first computing system identifies a first set of nearest neighbor profiles based on the first share of the given user profile and a k-nearest neighbor model. The first computing system receives, from each of one or more second computing systems of the multiple MPC systems, data indicating a respective second set of nearest neighbor profiles identified by the second computing system based on a respective second share of the given user profile and a respective second k-nearest neighbor model trained by the second computing system.
Patent WO-2022076237-A1 (WO)
Inventor: O'DONOVAN BRIAN D
IPC: G01N33/574
Filed: 2021-09-30
Abstract: Les systèmes, les milieux, les compositions, les méthodes et les kits selon la présente divulgation se rapportent à un panel de biomarqueurs d'auto-anticorps pour la détection précoce de troubles prolifératifs de cellules du côlon, notamment du cancer colorectal. La présence ou les taux des auto-anticorps dans un échantillon biologique des panels d'auto-anticorps décrits dans l'invention peuvent être utilisés à des fins de génération de classificateurs, et en tant qu'entrées dans des modèles d'apprentissage automatique utiles pour classifier des sujets d'une population pour la détection de troubles prolifératifs de cellules du côlon.
Patent WO-2022072754-A1 (WO)
Title: Systems and methods for dynamic image processing
Inventor: HSIAO YUNG-CHIN
IPC: A63F13/67
Filed: 2021-09-30
Abstract: The present disclosure relates to system for dynamic image processing to improve a viewer's interaction with the real world by applying a virtual image display technology. The system for dynamic image processing comprises a target detection module configured to determine a target object for a viewer; an image capture module configured to take a target image of the target object; a process module to receive the target image, process the target image based on a predetermined process mode, and provide information of a virtual image related to the target image to a display module; and the display module configured to display the virtual image by respectively projecting multiple right light signals to a viewer's first eye and corresponding multiple left light signals to a viewer's second eye.
Patent WO-2022125211-A1 (WO)
Inventor: JAIN ANJALI SINGHAI
IPC: H04L41/00
Filed: 2021-10-28
Abstract: Examples described herein relate to one or more processors, when operational, to execute instructions stored in memory device, to cause performance of: execute a driver that is to: negotiate capabilities of hardware with a control plane for a virtualized execution environment and limit capabilities of the hardware available to the virtualized execution environment based on a service level agreement (SLA) associated with the virtualized execution environment. In some examples, the driver is to advertise hardware capabilities requested by the virtualized execution environment. In some examples, the control plane is to set capabilities of a hardware available to the virtualized execution environment based on the SLA.
Patent WO-2022098891-A1 (WO)
Inventor: AL-SARKHI ABDELSALAM MOHAMMAD
IPC: B01F23/451
Filed: 2021-11-04
Abstract: L'invention concerne des systèmes pour la génération d'émulsions stables pouvant utiliser un ou plusieurs éjecteur(s) de liquide-liquide pour mélanger l'huile avec de l'eau par des flux moteurs et d'aspiration pour produire l'émulsion sous forme de flux de décharge. Un ou plusieurs réservoir(s) d'énergie motrice peut/peuvent être en communication fluidique avec ledit un ou lesdits éjecteurs de liquide-liquide; ledit ou lesdits réservoir(s) d'énergie motrice peut/peuvent alimenter ledit ou lesdits éjecteurs de liquide-liquide avec un fluide moteur. Un ou plusieurs réservoir(s) d'aspiration peut/peuvent être en communication fluidique avec ledit ou lesdits éjecteurs de liquide-liquide; ledit un ou lesdits réservoir(s) d'aspiration peut/peuvent alimenter ledit ou lesdits éjecteur(s) de liquide-liquide avec un fluide d'aspiration. Un ou plusieurs réservoir(s) de décharge peut/peuvent être en communication fluidique avec ledit ou lesdits éjecteur(s) de liquide-liquide; ledit ou lesdits réservoir(s) de décharge peut/peuvent collecter une émulsion à partir dudit ou desdits éjecteur(s) de liquide-liquide. En outre, une conduite d'écoulement couplée au dit ou aux dits réservoir(s) de décharge peut alimenter les émulsions dans une formation de décharge.
Patent WO-2022104235-A1 (WO)
Inventor: LEDDY ALISON
IPC: A41F15/00
Filed: 2021-11-16
Abstract: La présente invention concerne un vêtement de maintien (10) comprenant un panneau avant (12) et un panneau arrière (14). Le panneau avant (12) comprend une couche interne (18) et une couche externe (20). La couche interne (18) comprend un premier bonnet (34), un second bonnet (34), et une première paire de sangles (62). La couche externe (20) comprend une seconde paire de sangles (64). La couche externe (20) est configurée pour fournir une compression lorsqu'elle est portée. La première paire de sangles (62) et la seconde paire de sangles (64) s'étendent chacune entre le panneau avant (12) et le panneau arrière (14). Le vêtement de maintien (10) comprend également une bande (16) définissant une ouverture de torse (22). La bande (16) s'étend sous le panneau avant (12) et le panneau arrière (14). Le vêtement de maintien (10) est configuré pour appliquer une tension latérale au premier bonnet (34) et au second bonnet (34).
Patent WO-2022104244-A1 (WO)
Inventor: BALINT ENDRE
IPC: F16L23/16
Filed: 2021-11-16
Abstract: L'invention concerne un ensemble d'étanchéité destiné à des brides. L'ensemble d'étanchéité comprend un coin, un premier élément d'étanchéité, un second élément d'étanchéité et un élément de fixation. Le coin comprend une première surface, une deuxième surface et une troisième surface. La première surface définit un vide sous pression conjointement avec une première bride et une seconde bride. Le premier élément d'étanchéité entre en prise avec la deuxième surface du coin et la première bride. Le second élément d'étanchéité entre en prise avec la troisième surface du coin et la seconde bride. L'élément de fixation accouple ensemble le premier élément d'étanchéité, la première bride, la seconde bride et le second élément d'étanchéité. Le coin coulisse vers les éléments d'étanchéité en réponse à une augmentation de la pression dans le vide sous pression. Les éléments d'étanchéité forcent les brides l'une vers l'autre en réponse au coulissement du coin vers le premier élément d'étanchéité et le second élément d'étanchéité.