baber/WOPTO huggingface dataset:
Patent AU-2021218895-A1 (AU)
Title: Biomarkers for oxytocin receptor antagonist therapy
Inventor: POHL OLIVER
IPC: C12Q1/6883
Filed: 2021-02-09
Abstract: The disclosure provides compositions and methods for determining the propensity of a subject (e.g., a female human subject) undergoing embryo transfer therapy to benefit from administration of an oxytocin receptor antagonist, as well as for treating such patients accordingly. Using the compositions and methods of the disclosure, a subject undergoing embryo transfer therapy may be selected for treatment with an oxytocin receptor antagonist on the basis of a pre-treatment gene signature. Additionally or alternatively, a subject that is undergoing embryo transfer therapy and that has been administered an oxytocin receptor antagonist may be monitored following treatment to determine whether the subject is responding to the oxytocin receptor antagonist or if subsequent dosing is desirable. Exemplary oxytocin receptor antagonists useful in conjunction with the compositions and methods of the disclosure include pyrrolidin-3-one oxime compounds, such as (3Z,5S)-5-(hydroxymethyl)-1-[(2'-methyl- 1,1'-biphenyl-4-yl)carbonyl]pyrrolidin-3-one O-methyloxime, among others.
Patent AU-2021229229-A1 (AU)
Title: Improved components of a fluid transfer apparatus
Inventor: KRIHELI MARINO
IPC: A61M39/10
Filed: 2021-09-10
Abstract: Described are improvements to components of fluid transfer apparatuses 
comprising a first component, e.g. a syringe, a connector component 
5 configured to connect between the first component and an adapter 
component that is configured to allow connection of the connector 
component to a second component of the drug transfer apparatus, e.g. to a 
drug vial. The improvements include inter alia: changes to the sealing 
elements that seal the proximal end of the syringe, redesign of a septum 
10 holder inside the connector component and corresponding redesign of the 
housing of the connector component; changes to the structure of the end of 
the connector component that connects to the first component to allow the 
first component to swivel relative to the connector component; and changes 
to the design of the adapter component to a second component of the drug 
15 transfer apparatus to allow it to mate with the redesigned housing of the 
connector component.
Patent AU-2021238505-A1 (AU)
Title: Personal protection equipment for protecting a user from airborne pathogens
Inventor: HERRING RODNEY
IPC: A41D13/11
Filed: 2021-03-15
Abstract: A disposable mask or optically transparent mask comprising a mask body is provided. The disposable mask includes a periphery, and straps attached to the mask body proximate the periphery for releasably retaining the mask on a user's face, the mask body including: an inner layer, which is a polymeric plastic material with a plurality of passageways therethrough, and which has an inner surface and an outer surface; and a porous glass filter which is functionalized with a visible light photocatalyst and abuts the outer surface of the inner layer. Apparel comprising fiberglass which is functionalized with a visible light photocatalyst is also provided.
Patent AU-2021241552-A1 (AU)
Title: Container and load basket for thermal management for processing in high pressure application
Inventor: PELFREY RICK D
IPC: B01J3/00
Filed: 2021-03-24
Abstract: A container or load basket (80, 90) constructed for addressing thermal stratification of a product in the container/load basket and addressing thermal stratification of the processing medium during high pressure processing with a pressurized processing medium. The container includes an upper section (86, 96) forming a volume for receiving the product to be processed and a truncated lower section forming the bottom of the container. The bottom of the container is defined by a floor or partition (84, 92) extending across the lower portion of the container.The floor or partition can be constructed from the same material from which the upper section of the container is formed or a material that is more adiabatically active than the material from which the upper section of the container is formed.
Patent AU-2021261839-A1 (AU)
Title: Process for the preparation of 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1h-1,2,4-triazol-3-yl)phenyl)amino)-n-(methyl-d3)pyridazine-3-carboxamide
Inventor: CHEN KE
IPC: A61K31/501
Filed: 2021-11-01
Abstract: The invention relates to an improved process for synthesizing 6
5 (cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)
N-(methyl-d3)pyridazine-3-carboxamide of the formula: 
N 1N 
MeO 
0 HN 
D3CN 0 
H N zN N ' 
H 
(I) 
10 
Compound I is currently in clinical trials for the treatment of auto-immune and 
auto-inflammatory diseases such as psoriasis.  
-38-
Patent AU-2021269344-A1 (AU)
Title: Circuit and method for controlling emergency braking for train
Inventor: LI ENLONG
IPC: B60T17/22
Filed: 2021-11-17
Abstract: A circuit and a method for controlling emergency braking for a train are provided. The 
circuit for controlling emergency braking for a train includes an electromagnetic switch, an 
execution circuit and a control circuit. A coil component of the electromagnetic switch and an 
emergency braking trigger component are arranged in the control circuit. A contact of the 
electromagnetic switch and an emergency braking electromagnetic valve are arranged in the 
execution circuit. When the emergency braking trigger component is triggered, the coil 
component of the electromagnetic switch is deenergized, to switch off the contact of the 
electromagnetic switch, so that the execution circuit and the control circuit are cut off to 
deenergize the emergency braking electromagnetic valve so as to perform emergency braking.
1003753414 
32 Execution 
Contact of the circuit 
Power supply 1 electromagnetic 
positive pole switch 
40 Control 
supply Emergency circuit50 
po pe yolebraking trigger component Emergency 
Coil component of an braking 
40 electromagnetic electromagnetic 
switch valve 
Power supply Emergency 
Per pole braking trigger negative 
component 
Power supply, Contact of the 
negative pole electromagnetic 4 
switch 
Figure 1 
KI K2 
K3 K4 
Figure 2 
- 1/3-
Patent AU-2021277707-A1 (AU)
Title: Anti-cd137 antibodies
Inventor: FRYE CHRISTOPHER CARL
IPC: A61P35/00
Filed: 2021-12-02
Abstract: The present invention relates to antibodies that bind to human CD137 and display 
agonist activity, and may be useful for treating solid and hematological tumors alone and in 
combination with chemotherapy and ionizing radiation.
Patent AU-2021284148-A1 (AU)
Title: Chromanol, quinone or hydroquinone compounds for treatment of sepsis
Inventor: BOUMA HJALMAR ROLAND
IPC: A61K31/353
Filed: 2021-06-02
Abstract: The invention relates to certain chromanol, quinone or hydroquinone compounds and derivatives thereof for treatment of sepsis and sepsis-induced organ dysfunction. Specifically, the present invention relates to chromanol compounds chosen from S-(6-hydroxy-2,5,7,8- tetramethylchroman-2yl)(piperazin-1-yl)methanone and S-(6-hydroxy-2,5,7,8- tetramethylchroman-2-yl)(4-(2-hydroxyethyl)piperazin-1-yl)methanone, and pharmaceutically acceptable salts thereof.
Patent AU-2021284228-A1 (AU)
Title: Wire strand attachment clip
Inventor: STEMPER DANIEL
IPC: E04H17/10
Filed: 2021-05-27
Abstract: A wire strand attachment clip (200) including a wire catch (210) that defines a wire strand receiving and holding area configured to receive a wire strand, and a plurality of attachment arms (240a, 240b, 270a, 270b) connected to and extending from the wire catch that are dimensionally and biasingly configured to be positioned on a support post (20) to attach the wire strand to that support post such that the attachment arms engage multiple surfaces of the support post.
Patent AU-2021285130-A1 (AU)
Title: N-cyanopyrrolidines with activity as USP30 inhibitors
Inventor: LUCKHURST CHRISTOPHER ANDREW
IPC: A61P25/28
Filed: 2021-06-03
Abstract: The present invention relates to a class of N-cyanopyrrolidines with activity as inhibitors of the deubiquitylating enzyme USP30, having utility in a variety of therapeutic areas, including conditions involving mitochondrial dysfunction, cancer and fibrosis: (formulae (I)(i) and (I)(ii)).
Patent AU-2021312225-A1 (AU)
Title: Antibody-conjugated chemical inducers of degradation of BRM and methods thereof
Inventor: DRAGOVICH PETER SCOTT
IPC: A61P35/00
Filed: 2021-07-20
Abstract: The subject matter described herein is directed to antibody-CIDE conjugates (Ab-CIDEs) that target BRM for degradation, to pharmaceutical compositions containing them, and to their use in treating diseases and conditions where BRM degradation is beneficial.
Patent AU-2021324578-A1 (AU)
Title: Novel flow manifold for cryoablation catheter
Inventor: PHAM CUONG
IPC: A61B18/02
Filed: 2021-07-27
Abstract: An ablation apparatus for creating a lesion in target tissue has a handle, an elongate shaft extending from the handle and a distal ablation portion. The distal ablation portion includes a cryogen flow manifold defining a plurality of fluid pathways between an insert body and a sleeve. Cryogen is circulated through the plurality of fluid pathways to create the lesion in the target tissue.
Patent AU-2021326397-A1 (AU)
Title: Controlling reactability of water-reactive aluminum
Inventor: SLOCUM ALEX
IPC: C01B3/08
Filed: 2021-06-17
Abstract: Materials, kits, and methods are directed to controlling reactability of activated aluminum to produce hydrogen when exposed to water. For example, a moisture-stabilized material may be treatable with one or more additives to form a water-reactive source of hydrogen. The moisture-stabilized material may include a bulk volume including aluminum, at least one activation metal disposed along the aluminum within the bulk volume, the at least one activation metal more noble than the aluminum, and a salt along at least an outer surface of the bulk volume, the salt dissolvable in water to form an ion-containing solution at a rate faster than a reaction rate of water with the aluminum of the bulk volume.
Patent AU-2021329343-A1 (AU)
Title: Compositions and methods for treatment of obesity
Inventor: VENN-WATSON STEPHANIE
IPC: A23L33/10
Filed: 2021-08-18
Abstract: Compositions including odd chain saturated fatty acids, and salts and derivatives thereof, and methods for treatment or prophylaxis of conditions related to healthy body weight maintenance are provided, including compositions and methods for supporting a healthy body weight, for satiety/reduced calorie consumption, and/or for efficient fat metabolism.
Patent AU-2021329374-A1 (AU)
Title: Antigen binding proteins with non-canonical disulfide in FAB region
Inventor: Garces Fernando
IPC: C07K16/46
Filed: 2021-08-19
Abstract: The ability to generate a single antibody-based construct that can recognize multiple targets simultaneously, is paramount to advance many therapeutics candidates to clinic. Often, this implies extensive protein design with vary degrees of success. In the case of multispecific antibodies, the driving of the HC/LC pairing in the Fab region represents one of the most difficult challenges yet in the field of multispecific engineering. Described here is the discovery of a new placement for a non-canonical disulfide bond and as such the generation of an asymmetric cysteine interface between two Fabs present in the same molecule which will further enable the production of multispecifics.
Patent AU-2021347690-A1 (AU)
Title: Cancer therapy using toll-like receptor agonists
Inventor: KATZ STEVEN
IPC: A61K9/00
Filed: 2021-09-21
Abstract: Embodiments of the present invention provide for methods of treating cancer and methods of delivering toll-like receptor (TLR) agonists to solid tumors in the pancreas using a locoregional therapy through the vasculature. In one aspect, the present invention relates to a method of treating pancreatic cancer comprising administering TLR agonists to the pancreas.
Patent AU-2021352111-A1 (AU)
Title: Amidated peptides and their deamidated counterparts displayed by non-hla-a*02 for use in immunotherapy against different types of cancers
Inventor: HUKELMANN JENS
IPC: C07K16/28
Filed: 2021-09-29
Abstract: The invention relates to a peptide comprising an amino acid sequence selected from the group consisting of (i) SEQ ID NO: 1 to SEQ ID NO: 113, and (ii) a variant sequence thereof which maintains capacity to bind to MHC molecule(s) and/or induce T cells cross-reacting with said variant peptide, or a pharmaceutically acceptable salt thereof.
Patent AU-2021359597-A1 (AU)
Title: Self levelling trailer and loading ramps
Inventor: COLEMAN IAN ROBERT
IPC: B60G17/017
Filed: 2021-10-13
Abstract: A heavy vehicle and machinery trailer comprising: (i) a trailer base having a plurality of wheels and suspension means; (ii) a trailer bed supported on the trailer base by the suspension means; (iii) loading ramps connected to the trailer bed wherein the suspension means, or other methods such as hydraulically operated landing legs, are adapted to allow an operator to alter the pitch and/or roll angle of the trailer bed relative to the ground surface and wherein the loading ramps are adapted to have varying lengths such that when they are extended to the ground on a sloped surface, the lengths can be adjusted so that the ramps are evenly pitched. Further, the trailer has a hydraulic system under the control of an electrical controller which is operated by a user either by control panel or remote control. The electrical controller has a preset matrix of safe loading and unloading parameters which it uses to determine whether the sensed state of the trailer is safe for loading or unloading.
Patent AU-2021365666-A1 (AU)
Title: Apparatus, sensor, sensing method, sensor system, and power generation method
Inventor: NAKAGAWA SATOSHI
IPC: H01M14/00
Filed: 2021-08-11
Abstract: The purpose of the present invention is to detect a trace substance and generate energy by adsorption of the trace substance.　The present invention provides an apparatus comprising a first electrode and a second electrode, wherein: the first electrode and the second electrode are not electrically connected to each other; the shortest distance between the first electrode and the second electrode is 0.001-100 μm inclusive; the absolute value of a difference between a standard electrode potential of the first electrode and a standard electrode potential of the second electrode is 0.1 V or greater; and the surfaces of the first electrode and the second electrode are exposed partially or entirely. This apparatus further comprises a base material, and the first electrode and the second electrode are physically connected to each other through intermediation of the base material. Further, in this apparatus, the shortest distance between the first electrode and the second electrode is 10 μm or less.
Patent AU-2021381325-A1 (AU)
Title: Compounds, compositions, and methods for treating inflammatory or immune-mediated conditions of surface tissues
Inventor: BASSAGANYA-RIERA JOSEP
IPC: A61P17/00
Filed: 2021-11-17
Abstract: Compounds, compositions, and methods for treating inflammatory or immune-mediated conditions of surface tissues. The methods preferably involve topically administering to a surface tissue an amount of a compound of formula (I) effective to treat an inflammatory or immune-mediated condition. The compounds include lanthionine synthetase C-like 2 (LANCL2) agonists, such as piperazine-l,4-diylbis((6-(IH-benzo[d]imidazo-2-yl)pyiidine-2- yl)methanone) and salts and analogs thereof. The surface tissues include the skin and the mucosa, such as the oral mucosa. The inflammatory or immune-mediated conditions include psoriasis and dermatitis (such as atopic dermatitis), among others.
Patent AU-2021385036-A1 (AU)
Title: Treatment and prevention of neuropathology associated with neurodegenerative diseases
Inventor: RUBIN KEITH
IPC: A61P25/28
Filed: 2021-11-16
Abstract: Administering a live, attenuated
Patent AU-2021391411-A1 (AU)
Title: 5'-o-phenylacetyluridine and therapeutic use
Inventor: GARCIA GARCIA ROLANDO ALEJANDRO
IPC: A61P1/16
Filed: 2021-11-30
Abstract: 5' -O-Phenylacetyluridine effectively delivers both phenylacetate and uridine to a subject. It can be used to treat hepatic encephalopathy and genetic disorders of the hepatic nitrogen cycle.
Patent AU-2022200661-A1 (AU)
Title: Control device
Inventor: HUANG WEIWEI
IPC: H05K7/20
Filed: 2022-02-02
Abstract: oi 
101 
9 0 4 8 
7 
10 
6 601 
FIG. 1 
502 
50 1 302 
10 
7 
FIG. 2
ABSTRACT 
The present disclosure discloses a control device, which comprises: a circuit board; a heat 
dissipation cover, comprising a heat dissipation cover plate and a plurality of heat dissipation fins 
arranged on the heat dissipation cover plate, wherein the heat dissipation cover plate covers the 
circuit board, and a groove is formed between the plurality of heat dissipation fins; a thermally 
conductive strip, a first surface of which abutting against the circuit board, and a second surface of 
which abutting against the heat dissipation cover plate; and a fan arranged in the groove. The heat 
dissipation cover disclosed herein covers the circuit board as a holistic upper cover, the heat of the 
circuit board is conducted to the heat dissipation cover through the thermally conductive strip, and 
the fan in the through groove generate an airflow to dissipate heat, thereby realizing sealing, 
dustproof and heat dissipation of the circuit board simultaneously.  
FIG. 1
Patent AU-2022202029-A1 (AU)
Title: An Improved Artificial Valve
Inventor: FORSELL PETER
IPC: A61F2/24
Filed: 2022-03-23
Abstract: An artificial valve (5; 10; 20; 30; 50) for implantation in a mammal body, in or adjacent to a 
blood vessel, comprising a, casing (12; 37; 61) and a closing mechanism. Part of the 
closing mechanism is a moving part (11; 21, 22; 31, 32, 33; 51) adapted to make 
movements to assume an open and closed position for opening and closing of the blood 
vessel and positions between said open and closed positions, the closing mechanism (11; 
21, 22; 31, 32, 33; 51) is adapted to let the moving part initiate and carry out its movements 
when a predefined threshold value is reached by a physical parameter of the mammal or a 
functional parameter of a device (8) used by the mammal. The closing mechanism is 
arranged to power at least one of said movements of the moving part (51) and to let a 
movement of the moving
Patent AU-2022203009-A1 (AU)
Title: Patient test data processing system and method
Inventor: OLIPHANT IAIN
IPC: G16H10/20
Filed: 2022-05-05
Abstract: A method at a server system for processing patient test data to provide a more 
automated method of inputting point of care test data into an electronic health record 
avoiding user intervention. Point of care test data can be automatically completed and 
uploaded into an electronic health record. If a point of care test order is required in an 
electronic health record, it can automatically be created or identified for the uploading 
of point of care test data to the electronic health record for association with the 
automatically created or identified order.
Patent AU-2022206763-A1 (AU)
Title: Anti-backlash retention socket
Inventor: GUPTE ANUP A
IPC: B25B23/10
Filed: 2022-07-21
Abstract: A socket having a working end with a work piece aperture that is adapted to receive a 
work piece and an opposing drive end adapted to engage a torque application tool. The socket 
includes a biasing member adapted to apply a biased frictional force to the work piece 
received in the work piece aperture and including first and second opposing ends, where the 
first end is restricted from moving in the radial direction, and the second end includes a bent 
portion and is restricted from moving in the axial direction, and a groove formed in an 
internal surface of the work piece aperture. The bent portion engages the groove.  
18892236_1 (GHMatters) P119509.AU
1/3 
104 100 
102 
130 
116 120 
110 18 
112 
FIG. 1 
3 -,100 
110 
FIG. 2
Patent AU-2022215262-A1 (AU)
Title: Expansion joint element and system
Inventor: BENOY ADRIAN THOMAS
IPC: E04B1/68
Filed: 2022-08-11
Abstract: A method of manufacturing one or more expansion joint elements comprising: 
extruding a length of metal section having an upper surface and a lower surface, 
5 wherein one side length of the section is an anchoring side; cutting an intermeshing 
profile along an opposite side of the section or along a middle portion; and forming 
fixing means in the anchoring side.  
18957736_1 (GHMatters) P100939.AU.2 11/08/22
Patent AU-2022229928-A1 (AU)
Title: Metal detectors, components of metal detectors and methods of detecting metal
Inventor: JOY PATRICK
IPC: G01V3/15
Filed: 2022-02-17
Abstract: A ground search metal detector, comprising a shaft, a probe, and a dual pivot axis-defining junction piece. The probe comprises an electromagnetic coil configured to generate a magnetic field. The shaft and the probe are each attached to the junction piece. The detector is configured to be adjusted between at least a first arrangement (in which the shaft is capable of pivoting relative to the junction piece about a first axis, and the probe is capable of pivoting relative to the junction piece about a second pivot axis that is non-parallel with the first pivot axis) and a second arrangement (in which the shaft is prevented from pivoting relative to the junction piece about a first pivot axis, or the probe is prevented from pivoting relative to the junction piece about a second pivot axis). Also, a probe assembly comprising a probe and a junction piece, and methods.
Patent AU-2022242740-A1 (AU)
Title: Compositions and methods for rapid covid-19 detection
Inventor: SONG XIN
IPC: C12N15/10
Filed: 2022-03-21
Abstract: The present disclosure provides compositions and methods related to the detection of pathogenic organisms. In particular, the present disclosure provides compositions and methods related to the detection and/or quantification of viral RNA in a sample from a subject that has, or is suspected of having, a SARS-CoV-2 infection. Using rapid reverse-transcription loop-mediated isothermal amplification (RT-LAMP), the compositions and methods of the present disclosure provide a portable, inexpensive, rapid, and accurate assay platform for detecting and/or quantifying the presence of a pathogenic organism (e.g., SARS-CoV-2) in a patient sample.
Patent AU-2022271569-A1 (AU)
Title: Choke device and an assembly to supply a granular or powder product provided with the choke device, in particular for an automatic beverage vending machine
Inventor: BRUZZESE FABIO
IPC: G07F13/00
Filed: 2022-05-10
Abstract: In an automatic beverage vending machine (1), a feed assembly (18) for feeding a granular or powder product has a feed duct (22) for feeding the granular or powder product and a choke device (33) configured to receive and choke at least partially an elastically deformable discharge section (25) of the feed duct (22); the choke device (33) comprising a fixed attachment frame (34), a choke member (36) and a motorized movement assembly (44) for moving the choke member (36) between a support position, in which it maintains the discharge section (25) in a product feed condition, and an overturned position, in which it elastically deforms and chokes at least partially the discharge section (25).