Patent SG-11201407653S-A (SG)
Title: Herbal composition for treatment of gastrointestinal inflammatory diseases and method to prepare and use thereof
Inventor: ZHAO AIPING
IPC: A23L33/00
Filed: 2013-05-20
Abstract: (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 28 November 2013 (28.11.2013) WIPOIPCT (10) International Publication Number WO 2013/177067 A3 (51) International Patent Classification: A23L 1/29 (2006.01) A61K36/00 (2006.01) A61K9/00 (2006.01) (21) International Application Number: PCT/US2013/041873 (22) International Filing Date: 20 May 2013 (20.05.2013) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 61/649,287 19 May 2012 (19.05.2012) US (72) Inventors; and (71) Applicants : ZHAO, Aiping [CN/US]; 10383 Tuscany Road, Ellicott City, MD 21042 (US). ZHU, Kejin [CN/US]; 8957 Heath Cove, Cordova, TN 38016 (US). XIAO, Wei [CN/CN]; 58 Haichang South Road, XinPU, LianYungang, Jiangsu 222001 (CN). WANG, Zhenzhong [CN/CN]; 58 Haichang South Road, XinPu, LianYungang, Jiangsu 222001 (CN). (74) Agents: DING, Cong et al.; Suite 800, 401 Commerce Street, Nashville, TN 37219 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, [Continued on next page] (54) Title: HERBAL COMPOSITION FOR TREATMENT OF GASTROINTESTINAL INFLAMMATORY DISEASES AND METHOD TO PREPARE AND USE THEREOF l> o l> l> I- 1 \"* I». f Jpf > J¥ pY y y v y FIG.1 & fl | • E 15.0 12.5 1M 7.5- 2.® 1 nl n n nil 1 It! (57) Abstract: The present invention relates to a herbal composition to treat gastrointestinal inflammatory dis­ eases in a subject suffering therefrom. The present in­ vention further provides method a to use a pharmaceut­ ical effective amount of the herbal composition to treat G1 inflammatory diseases. Particularly, this invention relates to using a pharmaceutically effective amount of the herbal composition extract having the ability to in- nibit the expression of pro-inflammatory cytokines, at­ tenuate disruption of epithelial barrier, and modulate gut function WO 2013/177067 A3 I lllll llllllll II llllll III lllll lllll III III III lllll lllll lllll lllll lllll llll lllllll llll llll llll TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). Published: — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) (88) Date of publication of the international search report: 16 January 2014 — with international search report (Art. 21(3))