baber/WOPTO huggingface dataset:
Patent MX-2022014576-A (MX)
Title: 3-((1h-pyrazol-4-yl)methyl)-6'-(phenyl)-2h-(1,2'-bipyridin)-2-one derivatives and related compounds as gpr139 antagonists for use in a method of treatment of e.g. depression.
Inventor: MIKAMI SATOSHI
IPC: A61P25/36
Filed: 2021-05-20
Abstract: The present invention refers to compounds of formula (I). The present invention also relates to compounds of formula (I) for use as G Protein coupled Receptor 139 (GPR139) antagonists in methods of medical treatment of e.g. depression, Alzheimer's disease, schizophrenia, drug addiction, sleep disorders, pain, and attention deficit hyperactivity disorder. Exemplary compounds are e.g. 3-((1H-pyrazol-4-yl)methyl)-6'-( phenyl) -2H-(1,2'-bipyridin)-2-one derivatives and related compounds. The present description discloses the synthesis and characterisation of exemplary compounds, pharmacological data thereof, as well as exemplary tablet formulations comprising the compounds of the invention (e.g. page 83 to page 110; examples 1 to 33; reference example 1; test examples 1 and 2; tables 1 to 4).
Patent MX-JL02000034-A (MX)
Title: Liquids ispensing container for human consumption.
Inventor: FERNANDO TOPETE DAVILA
IPC: B67C9/00
Filed: 2002-10-03
Abstract: The present discloses a dispensing container of liquids for human consumption, such as syrups, jellies, marmalades, sweets, pulps, or any other comestible product; comprising a receptacle for containing said product and a removable lid for covering the product dispensing section in order to protect it from contaminants and thus avoiding leaks. The receptacle has an opening for the product to ooze out and a dosing system in said opening which consists in a sphere inserted in such a way that it can rotate and with it favor the controlled oozing out of the comestible product from the receptacle. The dispensing container also has a double fastening system of the lid in two different positions and a gripping section to facilitate its handling by the consumer.
Patent MX-PA00002681-A (MX)
Title: Fastener having primary and secondary threads.
Inventor: JOHN J HSING
IPC: F16B33/02
Filed: 2000-03-16
Abstract: In a fastener having a head and a shank having a generally cylindrical portion with a proximal end adjoining the head and with a distal end, the shank has a primary thread formation and a secondary thread formation. The primary thread formation has a generally uniform radial dimension along the generally cylindrical portion. In one embodiment, the secondary thread formation has a radial dimension tapering outwardly so as to increase continuously from a region where the secondary thread formation originates near the distal end to a region where the secondary thread formation has a maximum radial dimension, which is equal approximately to the generally uniform radial dimension, the latter region being closer to the distal end than to the proximal end. If the secondary thread formation is interrupted, tapping torque is lower, as compared to tapping torque if the secondary thread formation is continuous. In another embodiment, the secondary thread formation has a radial dimension tapering outwardly so as to increase continuously from a region where the secondary thread formation originates near the distal end to a region where the secondary thread formation has a maximum radial dimension, which is less than the generally uniform radial dimension, the latter region being at the proximal end.
Patent MX-PA00003499-A (MX)
Title: Luminaire starting aid device.
Inventor: JEFF WALTERS
IPC: H05B37/03
Filed: 2000-04-10
Abstract: A starting aid for a luminaire includes a trigger circuit for supplying a trigger voltage pulse to a lamp in response to the presence of a line voltage signal supplied by a photodetector, a feedback circuit for detecting the lamp voltage and means, responsive to the line voltage signal and the feedback circuit, for comparing the voltage on the lamp to a nominal voltage level for disabling the trigger circuit and terminating the trigger voltage pulse in the presence of a lamp cycling or lamp out condition.
Patent MX-PA00009939-A (MX)
Title: Process for manufacturing a captive screw.
Inventor: ELLIS THOMAS J
IPC: F16B5/02
Filed: 1999-04-08
Abstract: A method of making a knob (30) and ferrule (50) for a captive screw (10) is disclosed, the knob (30) integrally attached to the screw (10), the ferrule (50) attachable to a panel (60). The method of making the knob (30) includes providing an aluminum alloy base metal for the knob (30), pressing by cold-forming the base material into a generally cylindrical cup-shaped article (32) using at least one pressing operation, the cup having a generally cylindrical side wall (33), removing any base material situated outside of the perimeter of the cup-shaped article (32) and providing a hole in the bottom of the cup (32), coaxial with the hollow cylindrical walls (33) of the cup (32), thereby forming the knob (30).
Patent MX-PA00012968-A (MX)
Title: Bottle security device.
Inventor: BELDEN DENNIS D JR
IPC: B65D50/06
Filed: 1999-06-23
Abstract: A bottle security device (10) includes an inner member (14) and an outer member (12) that cooperate to lock the device on the neck (16) of a bottle (18). The inner member (14) has a plurality of fingers (26) that are adapted to fit under a bead on the neck. The inner member further has outwardly extending teeth (36). The outer member (12) slides over the inner member (14) and forces the fingers (26) against the bottle. The outer member (12) further includes a plurality of upwardly extending arms (60) that have inwardly projecting teeth (68) to engage with the teeth (26) of the inner member. A key (20) is used to separate the inner and outer member to release the device from the bottle by moving the upwardly extending arms outwardly to disengage the cooperating teeth.
Patent MX-PA01000582-A (MX)
Title: Removable tube heat exchanger and header plate.
Inventor: JANEZICH ROBERT
IPC: F28F9/14
Filed: 1999-07-14
Abstract: A header plate (10, 14) for a heat exchanger (2) comprising, in combination: a plate (10, 14) having a tube side and a tank side; a plurality of apertures (16, 18) extending through the plate (10, 14); each aperture (16, 18) having a wall of non uniform diameter at at least three locations (30, 32, 36) including a seal (50) fixedly engaged within the aperture (16, 18).
Patent MX-PA01004309-A (MX)
Title: Multi-loci genomic analysis by a method of improved cycle sequencing.
Inventor: VINAYAGAMOORTHY THURAIAYAH
IPC: C12Q1/6869
Filed: 1999-10-01
Abstract: The invention provides a method of sequencing a nucleic acid in a reaction mixture comprising first and second nucleic acid target sequences. The target sequences may be present on the same or different nucleic acid molecules. First and second labelled sequencing primers are provided that are hybridizable, respectively, to the first and second nucleic acid target sequences. The second sequencing primer being at least as long as the total length of the first sequencing primer plus the length of the first target sequence. Each of the sequencing primer extension products beginning with the second sequencing primer will be longer than the primer extension products in the pool beginning with the first sequencing primer. Once the sequencing reactions have been completed, the lengths of the primer extension products in the pool may be detected by known means, such as by gel electrophoresis.
Patent MX-PA01009904-A (MX)
Title: Process for the preparation of hydroxy methylthiobutyric acid esters.
Inventor: GARRAIT MICHEL
IPC: C07C319/20
Filed: 2000-03-30
Abstract: A process for the preparation of 2-hydroxy-4-methylthiobutyric acid ester which comprises (a) a first step of reacting 2-hydroxy-4-methylthiobutyronitrile with sulphuric acid to produce 2-hydroxy-4-methylthiobutyramide, and (b) a second step of reacting the 2-hydroxy-4-methylthiobutyramide with an alcohol to produce a 2-hydroxy-4-methylthiobutyric acid ester, the two steps being carried out in the same reaction medium.
Patent MX-PA01011355-A (MX)
Title: Process for separating functionalized alpha olefins from functionalized internal olefins.
Inventor: FONG HOWARD LAM-HO
IPC: C07C45/85
Filed: 2000-05-09
Abstract: A process for treating a feedstock comprised of functionalized alpha olefins and functionalized internal olefins, comprising: a) contacting the feedstock with a linear polyaromatic compound under conditions effective to form a reaction mixture comprising a linear polyaromatic compound-functionalized alpha olefin adduct; b) separating the linear polyaromatic compound-functionalized alpha olefin adduct, and optionally the unreacted linear polyaromatic compound as well, from the reaction mixture, to form a functionalized adducted alpha olefin stream and a functionalized internal olefin stream; c) dissociating the linear polyaromatic compound-functionalized alpha olefin adduct in said functionalized adducted alpha olefin stream to form a linear polyaromatic compound and a functionalized alpha olefin composition, and optionally d) separating the linear polyaromatic compound formed in step c) from a functionalized alpha olefin composition; whereby the concentration of functionalized alpha olefin in said alpha olefin composition is enriched over the concentration of functionalized alpha olefin in the feedstock.
Patent MX-PA02000348-A (MX)
Title: Needleless syringe comprising an injector with nested elements.
Inventor: ALEXANDRE PATRICK
IPC: A61M5/30
Filed: 2000-06-30
Abstract: . The invention concerns the field of needleless syringes for injecting an active principle for therapeutic purposes. More particularly, it concerns a needleless syringe for injecting an active principle (7) initially set between an injector (1, 10) comprising at least an injection nozzle, said injector being contacted with the skin, and a wall (8) mobile under the effect of a propelling system (9) pressurising and expelling the active principle through the injector located at the syringe downstream end (2). In order to produce nozzles in a considerable injector thickness and to control the jet coherence distance, said injector (1, 10) comprises at least two elements (3, 4) whereof the contact surfaces (30, 40, 40') are oriented towards the skin, at least a groove (31, 41, 41') forming an injection nozzle in the assembly of said elements.
Patent MX-PA02007898-A (MX)
Title: Gussetted plastic bag.
Inventor: SIMHAEE EBRAHIM
IPC: B31B50/64
Filed: 2001-02-15
Abstract: A plastic T shirt bag comprises an extruded plastic tubular form having side gussets and a seal line (14) at the bottom of the bag. The junctions (24) of the inner folds of the gussets and the seal line (14) are the weakest areas of the bottom of the bag. A reinforcement tape (30) extends across both weakened areas and takes up the forces applied to them when the bag is loaded.
Patent MX-PA02009335-A (MX)
Title: Cestrum yellow leaf curling virus promoters.
Inventor: LIGON HOPE THOMPSON
IPC: A01H5/00
Filed: 2001-03-26
Abstract: This invention describes novel DNA sequences that function as promoters of transcription of associated nucleotide sequences. More specifically, this invention describes DNA sequences conferring constitutive expression to an associated nucleotide sequence. The invention also describes recombinant sequences containing such promoter sequences. The said recombinant DNA sequences may be used to create transgenic plants, but especially plants expressing a nucleotide sequence of interest at all times and in most tissues and organs.
Patent MX-PA02009527-A (MX)
Title: Information storage medium containing multi-language markup document information, apparatus for and method of reproducing the same.
Inventor: CHUNG HYUN-KWON
IPC: G11B20/00
Filed: 2002-09-27
Abstract: An information storage medium containing multi-language markup document information, and an apparatus for and a method of reproducing the information storage medium which includes audio/video (AV) data, multiple markup documents which contain text information to be displayed in a selected language with a video picture decoded and reproduced from the AV data, and multi-language markup document information for designating one of the multiple markup documents as a markup document in the selected language. Accordingly, the information storage medium allows the reproducing apparatus to display the text information included in the markup document in the interactive mode in respective multiple languages.
Patent MX-PA02010642-A (MX)
Title: Dna transfection system for the generation of infectious influenza virus.
Inventor: HOFFMANN ERICH
IPC: C12N1/15
Filed: 2001-04-27
Abstract: The present invention is based on the development of a dual promoter system (preferably a RNA pol I pol II system) for the efficient intracellular synthesis of viral RNA. The resultant minimal plasmid based system may be used to synthesize any RNA virus, preferably viruses with a negative single stranded RNA genome. The viral product of the system is produced when the plasmids of the system are introduced into a suitable host cell. One application of the system is production of attenuated, reassortant influenza viruses for use as antigens in vaccines. The reassortant viruses generated by cotransfection of plasmids may comprise genes encoding the surface glycoproteins hemagglutinin and neuraminidase from an influenza virus currently infecting the population and the internal genes from an attenuated influenza virus. An advantageous property of the present invention is its versatility; the system may be quickly and easily adapted to synthesize an attenuated version of any RNA virus. Attenuated or inactivated RNA viruses produced by the present invention may be administered to a patient in need of vaccination by any of several routes including intranasally or intramuscularly.
Patent MX-PA02012124-A (MX)
Title: Transmission barrier layer for polymers and containers.
Inventor: HU ING-FENG
IPC: C08J7/048
Filed: 2001-06-04
Abstract: A barrier to diffusion of gas through polymers by means of plasma generated coating on polymeric substrates. The coating is suitable for application on planar polymeric substrates such a sheet or film. The coating is suitable for application on three-dimensional polymeric substrates, such as polymeric containers, or bottles.
Patent MX-PA02012610-A (MX)
Title: Two sided piloted weld nut.
Inventor: CLARKE LEE
IPC: F16B37/06
Filed: 2000-08-15
Abstract: A two sided piloted weld nut enables the nut to be welded either way. It can be used with a nut feeder, or to increase production on manual welding process. These nuts will eliminate the root cause of common nuts being welded upside down.
Patent MX-PA02012831-A (MX)
Title: Composition for gypsum plaster base board, method for preparing same and for making gypsum plaster base boards.
Inventor: LECLERCQ CLAUDE
IPC: C04B14/06
Filed: 2001-07-03
Abstract: The invention concerns a gypsum plaster base board composition comprising: 55 to 92 % of calcium sulphate capable of being hydrated; 0.1 to 5 % of mineral and/or refractory fibres: 3 to 25 % of a mineral additive; 1 to 5 % of non-exfoliated vermiculite; 3 to 15 % of hydrated alumina. The invention also concerns a method for preparing said composition and a method for making gypsum plaster base boards. Said gypsum plaster base boards have improved fire resistance.
Patent MX-PA03001747-A (MX)
Title: Laundry bar comprising polymeric colorants.
Inventor: ONG TIONGKHOON
IPC: C11D3/37
Filed: 2001-08-27
Abstract: Colored detergent bars are provided comprising water soluble polymeric colorants that exhibit excellent non-staining performance on fabrics and other contacted surfaces, including manufacturing and/or washing equipment, are easy to process into the desired detergent bar compositions, and do not exhibit any appreciable harmful effects to the environment. The particular polymeric colorants utilized in this respect are of very high molecular weight (in order to assure staining will not occur on target cleaning surfaces), are extremely water soluble, provide excellent vivid and aesthetically pleasing color shades within the target bar compositions, and are present as liquid or waxy pastes at room and at processing temperatures. The ultimate laundry bar product thus exhibits highly pleasing colors for product distinction as well as for aesthetic purposes.
Patent MX-PA03002774-A (MX)
Title: Method and system for identification of firearms.
Inventor: VASQUEZ HOMERO A
IPC: F41A9/60
Filed: 2001-10-01
Abstract: A system and method for identifying, test firing, marking, and imaging firearm cartridge cases and firearms for use by firearm manufactures. The system and method includes five subsystems, which work in the following sequence: a firearm serial number recognition sub-system; a cartridge case recovery sub-system; a cartridge case sorting sub-system; a cartridge case marking sub-system; and an image acquisition sub-system (108). The firearm serial number recognition sub-system (130) reads the serial number of a firearm and stores it in a database. The cartridge case recovery sub-system recovers fired cartridge cases and transports them to the sorting sub-system. The cartridge case sorting sub-system identifies the orientation of the cartridge cases and reorients them, if necessary, for marking. The cartridge case marking sub-system stamps the firearm serial numbers on the cartridge cases. The serial number is encrypted in a 2D matrix (barcode) form on the casings. The image acquisition sub-system acquires the firing pin and breech face images of a cartridge case after reading the stamped serial number on its side.
Patent MX-PA03004646-A (MX)
Title: Method for making heat-shrinkable skirt caps and resulting caps.
Inventor: GRANGER JACQUES
IPC: B29C48/90
Filed: 2001-11-23
Abstract: The invention concerns a method which consists in: a) forming by extrusion an extruded thermoplastic tube (20) having, when coming out of the extruder, a diameter D1; b) then subjecting said extruded tube of diameter D1 to a radiation treatment, so as to produced a cross-linked tube (21); c) after bringing said cross-linked tube (21) to a temperature not less than a temperature substantially equal to the melting point of its crystalline phase, subjecting it, in displacement, to a radial monoaxial expansion for form an expanded tube (22) of diameter D2, then cooling it down to a temperature, typically room temperature, at which it can be cut into tube portions (23) with length substantially equal to the height of said caps (1); and e) assembling or forming a head (10, 100, 101, 102, 103) on said tube portion (23), so as to obtain a cap or top (1), with heat-shrinkable skirt, economical and having a homogeneous skirt (11, 12) free of axial connection line.
Patent MX-PA03004996-A (MX)
Title: Safety shield for medical needles.
Inventor: THORNE GALE JR
IPC: A61J1/20
Filed: 2001-12-06
Abstract: A safety shield apparatus (10, 10 , 10, 310, 744, 810) is disclosed which includes a needle (20, 746, 820) having a distal protion (60, 747, 860) defining a longitudinal axis which is angularly displaced relative to a longitudinal axis defined bz a proximal portion (80, 746B, 880) of the needle (20, 746, 820). A shield (40, 40 , 340, 750, 840) is mounted wiht the needle (20, 746, 820) and extensible, via a tubular needle guide (150, 440, 638 , 850) movable along the needle (20, 746, 820) and extensible, via tubular needle guide (150, 440, 638 , 850) movable along the needle (20, 746, 820), between a retracted position and an extended position. The apparatus (10, 10 , 10, 310, 744, 810) may include a needle hub (30, 320, 758, 830) configured to support the proximal protion (80, 746B, 880) of the needle (20, 746, 820). The needle hub (30, 320, 758, 830) can include an appendage which may have at least one opening (748A) to facilitate manipulation thereof. A distal end of the shield (40, 40 , 340, 750, 840) can be attached to a planar contact surface (130, 130, 450, 752, 848). The shield (40, 40 , 340, 750, 840) may also include a latch (180, 200, 434, 437, 754, 846, 946) engageable with the needle (20, 746, 820).
Patent MX-PA03007675-A (MX)
Title: New compound [2r -(2r*, 3s*, 4r*, 5r*, 8r*, 10r*, 11r*, 12s*, 13s*, 14r*)]-13 -[(2, 6- dideoxy 3-c-methyi -3 -o-methyl -a-l-ribo -hexopyranosyl) oxy]-2-ethyl-3, 4, 10- trihydroxy -3, 5, 6, 8, 10, 12, 14-heptamethyl -11-[[3, 4, 6-trideoxy-3-(dimethyla
Inventor: JOSE MANUEL FRANCISCO LARA OCH
IPC: A61K31/00
Filed: 2003-08-27
Abstract: Provided herein is a new compound [2R -(2R*, 3S*, 4R*, 5R*, 8R*, 10R*, 11R*, 12S*, 13S*, 14R*)]-13 -[(2, 6-Dideoxy -3-C-methyI -3 -O-methyl a-L-ribo -hexopyranosyl)oxy] -2-ethyl-3, 4, 10- trihydroxy -3, 5, 6, 8, 10, 12, 14-heptamethyl -11-[[3, 4, 6-trideoxy -3-(dimethylamino) -'-D-xyl -hexopiranosil] oxy]-1-oxa-6 -azacyclopentadecan -15-one or with name of IUPAC 9- deoxo-9a -aza-9a -methyl-9a- homoerythromycin A and which is elucidated, for diverse physicochemical methods, which correspond with the and anhydrous and crystaline form with a tetragonal crystaline system, with spatial group P42212, cell constants a= 14.452 A0, b = 14.452 A0, c = 41.645 A0 and volume 8698 A03. Also herein is depicted the process for obtaining it starting from the amorphous forms, monohydrate, dehydrate, from its salts, from another by-product, from another polymorphous or pseudopolymorphous forms.
Patent MX-PA03011557-A (MX)
Title: A coated nicotine-containing chewing gum, manufacture and use thereof.
Inventor: KATARINA LINDELL
IPC: A61P25/28
Filed: 2002-06-14
Abstract: A coated chewing gum product for the delivering of nicotine in any form to a subject by a rapid transmucosal uptake in the oral cavity comprising at least one gum core, nicotine in any form and/or a nicotine mimicking agent, at lest one coating layer and optionally at least one or more other additive, wherein said at last one coating layer is buffered. Also contemplated is a method for the delivering of nicotine in any form, a method for the reduction of the urge to smoke or use tobacco as well as a method for producing said coated chewing gum and the use of the same form obtaining a quick transmucosal uptake of the nicotine in the oral cavity of a subject.
Patent MX-PA03011941-A (MX)
Title: 5-ht receptor ligands and uses thereof.
Inventor: YUAN-CHING PHOEBE CHIANG
IPC: A61P13/02
Filed: 2002-06-17
Abstract: Compounds of Formula (IA) that act as 5-HT receptor ligands andtheir uses in the treatment of diseases linked to the activation of 5-HT2 receptors in animals are described herein.
Patent MX-PA04000034-A (MX)
Title: T cell regulatory genes and methods of use thereof.
Inventor: VIJAY KUCHROO
IPC: A01K67/027
Filed: 2002-07-01
Abstract: A genetic locus and corresponding family of proteins associated with regulation of immune function and cell survival are provided. These genes encode cell surface molecules with conserved IgV and mucin domains. The locus comprising the TIM family is genetically associated with immune dysfunction, including asthma. Furthermore, the TIM gene family is located within a region of human chromosome 5 that is commonly deleted in malignancies and myelodysplastic syndrome. Polymorphisms in the gene sequences are associated with the development of airway hyperreactivity and allergic inflammation, and T cell production of IL-4 and IL-13. The proteins include the human hepatitis A cellular receptor, hHAVcr-1.
Patent MX-PA04000638-A (MX)
Title: Methods of drilling and completing well bores.
Inventor: BRADLEY L TODD
IPC: C09K8/86
Filed: 2004-01-21
Abstract: Methods of drilling and completing open hole well bores and methods of removing filter cake comprised of a gelling agent and calcium carbonate are provided. A method of the invention for removing filter cake comprised of a gelling agent and calcium carbonate from the walls of an open hole well bore is basically comprised of the steps of contacting the filter cake with a delayed clean-up solution comprised of water and a formate ester and removing the clean-up solution from the well bore.