baber/WOPTO huggingface dataset:
Patent DK-0919553-T3 (DK)
Inventor: TAKEMURA MAKOTO
IPC: A61K31/4709
Filed: 1997-07-11
Granted: 2005-06-06
Abstract: The present invention is to provide an antimicrobial agent having high safety as well as potent antimicrobial activity on broad range of microorganisms. A compound represented by the following formula, its salt and their hydrates: <CHEM> wherein R<1> and R<2> each independently represents a hydrogen atom or an alkyl group; n represents an integer of 1 to 3; R<3> represents an alkyl group, an alkenyl group, a halogenoalkyl group, a cycloalkyl group, an aryl group, a heteroaryl group, an alkoxyl group or an alkylamino group; R<4> represents a hydrogen atom or an alkylthio group; R<5> represents a hydrogen atom, an amino group, a hydroxyl group, a thiol group, a halogenomethyl group, an alkyl group, an alkenyl group, an alkynyl group or an alkoxyl group; X<1> represents a halogen atom or a hydrogen atom; and A represents a nitrogen atom or a partial structure represented by formula (II): <CHEM> wherein X<2> represents a hydrogen atom, an amino group, a halogen atom, a cyano group, a halogenomethyl group, a halogenomethoxyl group, an alkyl group, an alkenyl group, an alkynyl group or an alkoxyl group; and Y represents a hydrogen atom, a phenyl group, an acetoxymethyl group, a pivaloyloxymethyl group, an ethoxycarbonyl group, a choline group, a dimethylaminoethyl group, a 5-indanyl group, a phthalidinyl group, a 5-alkyl-2-oxo-1,3-dioxol-4-ylmethyl group, a 3-acetoxy-2-oxobutyl group, an alkyl, an alkoxymethyl group or a phenylalkyl group.
Patent DK-0946150-T3 (DK)
Inventor: CREMER KARSTEN
IPC: A61K9/20
Filed: 1997-08-29
Granted: 2002-06-24
Abstract: A tablet composed of co-adhesive layers comprises: (a) at least one matrix layer which (i) is swellable in an aqueous medium; (ii) contains at least one drug released in a retarded manner during the swelling, (iii) does not decompose during the swelling and (iv) contains crosslinked amylose; and (b) at least one adjuvant and/or substrate layer.
Patent DK-0923875-T3 (DK)
Inventor: LEADBEATER JOHN MICHAEL
IPC: A23L1/00
Filed: 1998-10-26
Granted: 2003-04-14
Abstract: The invention relates to a method of making food articles such as chocolate centres. The method comprises providing solidifiable liquid, providing a pair of parallel arranged rollers (2,3) having cavities (4) defined on their outer cylindrical surface, providing depositors (7,10) for depositing the liquid food onto said rollers. Liquid food is deposited into the cavities on the first roller to provide a first separate part of a food article (9), and into the cavities on the second roller to provide a second separate part of a food article (12). By counterrotating the rollers to move the roller surfaces towards one another and to join the separate parts into one food article (1). The invention also relates to an apparatus for this purpose. <IMAGE>
Patent DK-0908558-T3 (DK)
Inventor: LESKELAE MARKKU
IPC: D21H11/10
Filed: 1998-09-16
Granted: 2004-06-28
Abstract: The present invention concerns a method for producing a base paper for fine papers, the base paper being produced from a mixture of a mechanical pulp and a chemical pulp. The chemical pulp used comprises a chemical softwood pulp having a elastic modulus close to that of the mechanical pulp and a great bonding strength. It is preferred to use a chemical softwood pulp which produces a sheet having a elastic modulus of less than 6000 N/mm<2> when the bonding strength is 400 J/m<2>. A pulp of this kind has a good ScottBond strength at the same light scattering. The base paper produced by the method can therefore be used in double-coated fine papers which require a large bonding strength of the base paper.
Patent DK-0988378-T3 (DK)
Inventor: SOEDERLIND ULF HANS ESKIL
IPC: C07K16/44
Filed: 1998-01-26
Granted: 2004-01-26
Abstract: The present invention relates to a method for in vitro creation of molecular libraries evolution of protein function. Particularly, it relates to variability and modification of protein function by shuffling polynucleotide sequence segments. A protein of desired characteristics can be obtained by incorporating variant peptide regions (variant motifs) into defined peptide regions (scaffold sequence). The variant motifs can be obtained from parent DNA which has been subjected to mutagenesis to create a plurality of differently mutated derivatives thereof or they can be obtained from in vivo sequences. These variant motifs can then be incorporated into a scaffold sequence and the resulting coded protein screened for desired characteristics. This method is ideally used for obtaining antibodies with desired characteristics by isolating individual CDR DNA sequences and incorporating them into a scaffold which may, for example, be from a totally different antibody. <IMAGE>
Patent DK-0927305-T3 (DK)
Inventor: FRENKEN EGBERT
IPC: F04B1/34
Filed: 1998-04-25
Granted: 2003-05-05
Abstract: The invention relates to a piston pump (1) for delivering a fluid at low pressure and at a higher pressure, a higher delivery volume being provided in one pumping cycle at low pressure than at a higher pressure, having a low-pressure delivery piston (4), which is moved inside a pump cylinder (2) and acts upon a pressure chamber (7) under prestress into its delivery end position, a high-pressure delivery piston (11), an inlet valve (9) and an outlet valve (9, 10), a fluid delivery path (5) furthermore being provided between the inlet valve (9) and the outlet valve (10), and the low-pressure delivery piston (4) being able to be moved back counter to its prestress into a delivery starting position, and proposes, to achieve effective delivery at low pressure and at a higher pressure with the simplest possible construction, that the fluid delivery path (5) passes through the low-pressure delivery piston (4), that a valve (6) is provided in the low-pressure delivery piston (4), which valve shuts in the case of movement into the delivery starting position, that the high-pressure delivery piston (11) and the low-pressure delivery piston (4) operate in a common pressure chamber (7), and that the high-pressure delivery piston (11) moves the low-pressure delivery piston (4) counter to its prestress.
Patent DK-1016466-T3 (DK)
Inventor: THOMAS PHILLIPE ANDRE FERNAND
IPC: C09D7/12
Filed: 1999-07-19
Granted: 2002-06-24
Abstract: The invention provides for a substrate coated with a non-stick coating which resists abrasion force, the coating comprising a fluoropolymer resin containing ceramic particles to deflect the abrasion force away from the coating wherein the ratio of the thickness of the coating to the longest diameter of said ceramic particles is in the range of 0.8-2.0. <??>Further the invention provides for a substrate coated with a non-stick coating which resists abrasion force, the coating comprising an undercoat and an overcoat, each containing fluoropolymer resin, the undercoat also containing ceramic particles extending from the undercoat, the overcoat telegraphing the particles extending from the undercoat through the thickness of the overcoat to deflect the abrasion force away from the coating. Preferably, the ratio of the combined thickness of the undercoat and the overcoat to the longest diameter of the ceramic particles is in the range of 0.8-2.0. <??>The invention further comprises a composition capable of forming an adherent coating to a smooth substrate and exhibiting abrasion resistance, comprising fluoropolymer, polymer binder and inorganic filler film hardener, wherein at least 30 wt% of the film hardener is comprised of large ceramic particles having an average particle size of at least 14 micrometers. Preferably the amount of ceramic particles is sufficient to provide at least 3 such particles per 1 cm length of transverse cross section of coating formed from said composition. <IMAGE>
Patent DK-1062364-T3 (DK)
Inventor: SCHWEIGHOFFER FABIEN
IPC: C12Q1/68
Filed: 1999-03-11
Granted: 2005-09-05
Abstract: Method for identifying and/or cloning regions of nucleic acids that are differently spliced in two different physiological situations comprises hybridizing RNA originating from a test situation with cDNA originating from a reference situation and identifying and/or cloning nucleic acids corresponding to differential splicing. Independent claims are also included for the following: (1) a method for identifying and/or cloning regions of nucleic acids that are differently spliced in two different physiological situations A and B, comprising: (a) forming heteroduplexes in a liquid phase between mRNA originating from situation A and cDNA originating from situation B; (b) forming heteroduplexes in a liquid phase between mRNA originating from situation B and cDNA originating from situation A; and (c) identifying and/or cloning RNA regions that are not paired off in steps (a) and (b); (2) a method for identifying and/or cloning regions of nucleic acids that are differently spliced in two different physiological situations A and B, comprising: (a) forming heteroduplexes between mRNA originating from situation A and cDNA originating from situation B, where the mRNA or cDNA is immobilized on a support; (b) forming heteroduplexes between mRNA originating from situation B and cDNA originating from situation A, where the mRNA or cDNA is immobilized on a support; and (c) identifying and/or cloning RNA regions that are not paired off in steps (a) and (b); (3) a composition comprising nucleic acids identified and/or cloned by the above methods; (4) a nucleic acid composition comprising nucleic acids corresponding to alternative splicing that distinguishes two physiological situations of a cell or tissue; (5) libraries of nucleic acids or oligonucleotides specific for alternative splicing that distinguishes two physiological situations of a cell or tissue, or of microorganisms transformed with such nucleic acids; (6) a composition comprising a compound capable of interfering with the alternatively spliced products identified by the above methods. ACTIVITY : None given. MECHANISM OF ACTION : None given.
Patent DK-1104765-T3 (DK)
Inventor: LABRIOLA RAFAEL
IPC: A61K31/435
Filed: 1999-08-04
Granted: 2003-06-30
Abstract: It comprises reducing the hydroxy ester of formula (X) by reacting it in DMF and then with an iminium salt of formula (XIII) formed in situ with thionyl chloride and dimethylformamide, and subsequent reduction with an appropriate reducing agent to form the ester of formula (XII), which is then reacted with dimethylamine in a polyhydroxylated solvent medium at an appropriate temperature.
Patent DK-1149142-T3 (DK)
Inventor: GUPTA RAMESH
IPC: C10G65/04
Filed: 1999-10-20
Granted: 2005-01-31
Abstract: A hydroprocessing process for removing impurities from a feed comprising a hydrocarbonaceous liquid comprises at least two cocurrent, upflow hydroprocessing reaction stages and a non-catalytic, vapor-liquid contacting stage. The reaction and contacting stages may all be in the same reactor vessel. The feed and a hydrogen treat gas are passed up into a catalyst bed which comprises the first reaction stage, which produces a partially hydroprocessed liquid and vapor effluent. This first stage vapor is passed up into the contacting stage in which it contacts a hydrocarbonaceous liquid which reduces the vapor impurity content. The impurity-enriched contacting liquid passes down and mixes with the first stage liquid effluent. The combined effluents and hydrogen are passed up into the second reaction stage to form a processed product liquid and hydrogen-containing vapor effluent. This second reaction stage vapor effluent is passed up into the first stage to provide at least a portion of the hydrogen for the first stage reaction. Additional product liquid may be recovered by cooling the contacting and condensing the purified contacting stage vapor effluent.
Patent ES-2253145-T3 (ES)
Title: Instalacion de turbinas de vapor.
Inventor: HINZ HOLGER DIPL-ING
IPC: F01K23/10
Filed: 2000-01-12
Granted: 2006-06-01
Abstract: Instalación de turbinas de vapor (2B) con un generador de vapor (30), una turbina de vapor (22) y un circuito de agua y vapor (26), en la que el generador de vapor presenta una superficie calefactora de calentamiento previo (82) así como una superficie calefactora de recalentamiento (52), conectada en el circuito de agua y vapor (26), con una entrada de vapor (51), caracterizada porque la superficie calefactora de calentamiento previo (82) está configurada en forma de una superficie calefactora de calentamiento previo (82) separada del circuito de agua y vapor (26), que está conectada, en el lado de entrada, con una instalación (8), dispuesta fuera del circuito de agua y vapor (26), para la generación de vapor externo (F) que debe alimentarse al circuito de agua y vapor (26) y está conectada, en el lado de salida, con la entrada de vapor (51) de la superficie calefactora de recalentamiento (52).
Patent ES-2201955-T3 (ES)
Inventor: DE LONGHI GIUSEPPE
IPC: F24D19/06
Filed: 2000-01-17
Granted: 2004-04-01
Abstract: The independently operating mobile radiator comprising a body having a plurality of radiating members each defined by at least a first metal plate and a second metal plate mutually associated and by at least one central portion wherein fluid heated by heating means, circulates at a preset temperature, said radiating members being mutually connected through passage hubs for said heated fluid for its circulation inside said body which, in at least one region of the surface of the radiating members, external to said central portion wherein said heated fluid circulates, further has additional heating means at least for heating the surrounding air. <IMAGE>
Patent ES-2257236-T3 (ES)
Title: Dispositivo para calcular el flujo de la sangre en el acceso a un vaso.
Inventor: KLEINEKOFORT WOLFGANG
IPC: A61M1/14
Filed: 2000-04-13
Granted: 2006-08-01
Abstract: Dispositivo para el cálculo del flujo de la sangre en un acceso a un vaso para un dispositivo para el tratamiento extracorporal de la sangre, en el que la sangre llega a través de un ramal arterial de un circuito extracorporal, que se encuentra en unión fluida con el acceso al vaso en una conexión arterial, llega a la unidad de tratamiento de la sangre del dispositivo de tratamiento de la sangre y a través de un ramal venoso del circuito extracorporal de la sangre, que se encuentra en unión fluida con el acceso al vaso en una conexión venosa, se lleva de retorno, estando conectada en el circuito extracorporal una bomba de sangre, con una unidad de control (18) para variar el caudal de flujo de la bomba de sangre, un equipo de medición arterial y/o venosa (20, 22) para medir la presión part, pven en el ramal arterial y venoso (19, 21) respectivamente del circuito extracorporal (2) con el acceso al vaso abierto, mientras fluye sangre a través del mismo entre la conexión arterial y la venosa (12, 13) y para medir la presión part comp, pven comp en el ramal arterial y venoso (19, 21) respectivamente con el acceso al vaso interrumpido, mientras no fluye sangre a través del mismo entre la conexión arterial y la venosa, variando el flujo de la sangre QB en el circuito extracorporal entre las mediciones, una unidad de memoria (25) para memorizar los valores de la presión arterial y/o venosa medida, y una unidad de cálculo (27), que está configurada de tal manera que, a partir de al menos dos valores medidos de la presión arterial y/o venosa part, pven, puede determinarse, con el acceso al vaso abierto y al menos dos valores medidos de la presión arterial y/o venosa part comp, pven comp, con el acceso al vaso interrumpido, el flujo de la sangre QF en el acceso al vaso abierto entre la conexión arterial y venosa.
Patent ES-2261119-T3 (ES)
Inventor: KISSELBACH ANDREAS DIPL-ING
IPC: B23C3/12
Filed: 2000-05-16
Granted: 2006-11-16
Abstract: The wood cutting tool blade has a cutter blade with cutters placed around its periphery, each with a swarf gap (2). The gap extends over the axial width of the tool and opens at both front faces (3,4). Each cutter has an angled cutting section (6a). The swarf gap base (7) has a partially angled face.
Patent ES-2299414-T3 (ES)
Inventor: BLOCH KLAUS
IPC: A63B51/02
Filed: 2000-07-04
Granted: 2008-06-01
Abstract: Production of a monofilament (1) comprises: (i) extrusion with a linear bead (11a, 11b) along it; (ii) stretching to 1-10 times its length; (iii) heating to a temperature below melting point and twisting about its own axis, forming the spiral; and (iv) cooling.
Patent ES-2255947-T3 (ES)
Inventor: HEDEMANN RALF DIPL-ING
IPC: H04M17/00
Filed: 2000-07-27
Granted: 2006-07-16
Abstract: The method involves detecting the talk time (9) of outgoing calls made by the mobile terminal using a call time meter (10), and comparing it with a threshold value (12). The mobile terminal can be released for use with any subscriber identification module if the threshold value is exceeded. The comparison may be made when the terminal is switched on. At manufacture, the terminal may be restricted to the use of certain SIMs.  An Independent claim is included for a mobile radio terminal.
Patent ES-2292423-T3 (ES)
Inventor: DAVIS PETER DAVID
IPC: A61K31/4184
Filed: 2000-01-14
Granted: 2008-03-16
Abstract: Vascular damaging agents composed of substituted 5(6)-substituted benzimidazole-2-carbamates are provided. These agents are useful in the preparation of medicaments for the treatment of diseases involving neovascularisation, particularly for the treatment of solid tumors, macular degeneration, diabetic retinopathy, rheumatoid arthritis, psoriasis, and atherosclerosis. Embodiments include a 5(6)-substituted benzimidazole-2-carbamate of formula I wherein A represents a multi-substituted alkyl group or aromatic ring.
Patent ES-2208288-T3 (ES)
Title: Cuerpos moldeados de dioxido de titanio, procedimiento para su fabricacion y su uso.
Inventor: PROFT BERND
IPC: C04B35/46
Filed: 2000-01-31
Granted: 2004-06-16
Abstract: Procedimiento para la fabricación de cuerpos moldeados de dióxido de titanio con un tamaño medio de grano d50 de 0,01 a 50 mm, que se componen, en cada caso, de cristalitas primarias de óxido de titanio de la modificación de anatasa con un tamaño de cristalita según Scherrer de hasta 40 nm y que presentan una superficie específica, determinada según el método BET, de 20 a 150 m2/g, un volumen de poros de 0,1 a 0,45 cm3/g y un diámetro de poro de 100 a 300ºC, caracterizado porque el polvo de dióxido de titanio se trata previamente a una temperatura de 120 a 250ºC y a una presión de 2 a 40 bares por un período de 0, 1 a 30 horas en presencia de agua y se seca a continuación, así como porque los cuerpos moldeados, producidos a partir de una mezcla pastosa del polvo de dióxido de titanio tratado previamente y sol de dióxido de titanio y/o de ácido nítrico al 1 hasta 20% se secan y se recuecen a una temperatura de 400 a 1000ºC por un período de 0,5 a 3,5 horas, preferentemente, 1,5 a 2,5 horas.
Patent ES-2190955-T3 (ES)
Inventor: HARSCH ERICH
IPC: B21D43/10
Filed: 2000-03-02
Granted: 2003-09-01
Abstract: A press etc. has a processing station with independent transporter for a component. The transporter has a drive system for a pivot resp. transporter arm (13). The system has one or more stationary drive motors (8,9), each acting on a movement transmitter part (10,11). Regulation of direction and RPM resp. standstill of the motors generate a coordinated movement of the transmitter parts, and a movement superposition is used to adjust a programmable movement curve of the pivot/transporter arm. The arm is born on a slide (23) with linear guide (24), and has a drive lever. The transmitter parts consist of a toothed rack drive (8-12).
Patent ES-2232447-T3 (ES)
Title: Sistema para comprobar la presion de hinchado de los neumaticos de un vehiculo a motor.
Inventor: CARETTA RENATO
IPC: B60C23/04
Filed: 2000-05-24
Granted: 2005-06-01
Abstract: Sistema para comprobar por lo menos un parámetro de estado de un neumático para un vehículo a motor, que comprende: - por lo menos una rueda de neumático (1) que comprende un neumático (2) montado sobre una llanta de montaje (3); - un tubo interno (4) insertado en la cavidad definida entre el neumático y la llanta; - un dispositivo de medición para medir dicho por lo menos un parámetro de estado asociado con dicha rueda; - un dispositivo de transmisión diseñado para transmitir una señal que indica el valor medido por dicho dispositivo de medición, incluyendo dicho dispositivo de transmisión una batería de suministro de energía; - un dispositivo de recepción diseñado para recibir dicha señal que indica el valor medido por dicho dispositivo de medición; - un sensor para detectar el movimiento de dicha rueda, diseñado para permitir la activación de dicho dispositivo de transmisión cuando dicha rueda se mueve; caracterizado por el hecho de que dicho dispositivo de transmisión, dicho dispositivode medición y dicho sensor de movimiento están alojados en el mismo contenedor que está insertado en una pared de dicho tubo interno en una posición radialmente interna respecto a dicha rueda.
Patent ES-2203483-T3 (ES)
Inventor: SANTA CSABA
IPC: C07C51/285
Filed: 2000-05-26
Granted: 2004-04-16
Abstract: The invention relates to a new process for the synthesis of 17beta-hydroxy-17alpha-methyl-1,3-seco-2-nor-5alpha-androstane-3-acid derivatives of formula (I)wherein the meaning of Z is carboxyl or formyl group andto the new secoindoxylidene carboxylic acid derivatives of formula (II)wherein R1 and R2 independently are C1-C4 alkyl or alkoxy group, hydrogen or halogen atom-which are intermediates for preparing the compounds of formula (I).The 17beta-hydroxy-17alpha-methyl-1,3-seco-2-nor-5alpha-androstane-3-acid derivatives of formula (I) are intermediates in the synthesis of oxandrolon (17beta-hydroxy-17alpha-methyl-2-oxa-5alpha-androstane-3-one), which is used as anabolic in therapy.
Patent ES-2281351-T3 (ES)
Title: Tren de laminacion.
Inventor: SCHARLEMANN HORST
IPC: G01N27/72
Filed: 2000-06-14
Granted: 2007-10-01
Abstract: Tren de laminación, que se compone de por lo menos dos bastidores (2, 4) del laminador, los cuales son sucesivos entre si, y en el tren está dispuesto un dispositivo (1) para efectuar durante el proceso del laminado - una comprobación no destructiva, sobre todo de los materiales laminados en forma de unas barras, calientes por encima del punto Curie; dispositivo éste que se compone de un sistema con por lo menos dos bobinas de ensayo (20), el cual es giratorio alrededor del material de laminación, que está pasando, y el mismo puede ser impulsado por un medio refrigerante, que es aportado por un sistema de refrigeración (6) de los cilindros; este tren de laminación está caracterizado por la disposición del dispositivo (1) -que se compone de una parte rotatoria (14) así como de una parte estacionaria (13)- directamente por detrás de la salida del material de laminación desde uno de los bastidores (2) del laminador y por el sistema de refrigeración (6) de los cilindros, el cual está previsto para este bastidor; como asimismo está este tren de laminación caracterizado porque la aportación del medio refrigerante para el sistema de las bobinas de ensayo es efectuada aproximadamente dentro del plano (7) de la fijación del dispositivo (1) en el bastidor (2) del laminador y hacia el interior de la parte rotatoria (14), dentro de la cual está previsto un canal (18) para el medio refrigerante, el cual se extiende en la forma de una rosca hasta su cara frontal (23) entre el material de laminación y un cojinete de rotación (17) de la parte rotatoria (14); canal éste desde el cual conducen unas tuberías individuales (25) en el sentido radial hacia las respectivas bobinas de ensayo (20) que, al estar cumplidos unos determinados parámetros (como, por ejemplo, la fuerza centrífuga o la presión), pueden ser giradas para así ocupar su definida posición de medición.