baber/WOPTO huggingface dataset:
Patent CZ-280543-B6 (CZ)
Title: Process for preparing novel thienopyran derivatives
Inventor: BINDER DIETER DR
IPC: A61K31/45
Filed: 1990-06-26
Abstract: Thienopyran derivatives of the general formula   <IMAGE> I  in which the radial  <IMAGE>  denotes one of the formulae  <IMAGE>  R denotes hydrogen or a radical -CN, -CHO, -CH=NOH, -CONH2 or -COOR1, R1 denotes the radical (C1-C4)-alkyl and n denotes an integer 3, 4 or 5, and a process for their preparation, pharmaceutical preparation and their use for the treatment of diseases which can be cured by activation of membrane K+ channels, such as high blood pressure and asthma.
Patent CZ-278294-B6 (CZ)
Title: Compacting press for upsetting pieces of wire into globular and the like articles
Inventor: HECHT JURGEN
IPC: B30B1/10
Filed: 1989-07-14
Abstract: An upsetting press for swaging wire segments into balls or the like. The press includes a fixed matrix, a stamp holder provided for a stamp and mounted on a machine frame so as to be displaceable in the stamping direction, a cam drive mechanism for the stamp holder, and a gripper device provided for the wire segments. The cam drive mechanism is a double cam that is rotatably mounted in the machine frame. An angle lever is pivotably mounted in the machine frame. Follower rollers are carried by the angle lever and run on the double cam. A presser carriage is provided for the stamp holder and is guided in the machine frame in such a way that it can move back and forth. A knee lever is provided that has two arms, one of which is connected to the machine frame and the other of which is connected to the presser carriage. A connecting rod operatively interconnects the angle lever with the knee lever.
Patent CZ-279287-B6 (CZ)
Title: Girder system for three-joint structures
Inventor: FRANK PAVEL ING
IPC: E04C3/16
Filed: 1990-12-29
Abstract: The girder system for three-joint structures is formed by at least two booms (1), stands (2, 3) and diagonal braces (4). One of the booms (1) and the middle main stand (3) have modifications on their ends for joint connections, allowing the creation of three-joint structures. The diagonal braces (4), passing through the  joint connections of the braces (1) to the ends of the stands (2), are joined with the main stand (3) in the common joint connection, located under the lower boom (1). The diagonal braces (4) bear the stands (2) and laterally reinforce the girder system.<IMAGE>
Patent CZ-283525-B6 (CZ)
Title: Process for preparing 1,3-oxazolidine-5-carboxylic acid
Inventor: DENIS JEAN-NOEL
IPC: C07D263/04
Filed: 1993-11-18
Abstract: PCT No. PCT/FR93/01133 Sec. 371 Date May 19, 1995 Sec. 102(e) Date May 19, 1995 PCT Filed Nov. 18, 1993 PCT Pub. No. WO94/12482 PCT Pub. Date Jun. 9, 1994Method for the preparation of 1,3-oxazolidin 5-carboxylic acid having the general formula (I)   ormula (II)    <IMAGE>  (II)  In the general formulas (I) and (II), Ar is an aryl radical, R1 is a benzoyl radical or a radical R2-O-CO- wherein R2 is an alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, bicycloalkyl, phenyl or heterocyclyl radical, Ph is an optionally substituted phenyl radical, X is the residue of an optically active organic base or an alkoxy radical optionally substituted by a phenyl radical. The acids of formulas (I) and (II) are particularly useful in preparing taxol, Taxotere or analogs thereof which have remarkable antitumor and antileukemia properties.
Patent CZ-298209-B6 (CZ)
Title: Anthranilic acid derivatives as modulators of multidrug resistance, process of their preparation and use
Inventor: RYDER HAMISH
IPC: C07D409/14
Filed: 1997-10-17
Abstract: In the present invention, there are disclosed anthranilic acid derivatives of the general formula I wherein each of R to Re9 represents an organic substituent, n is 0 or 1, m is 0 or an integer of 1 to 6, q is 0 or 1, X is a direct bond, O, S, -S- (CHi2)ip- or -O- (CHi2)ip- wherein p is from 1 to 6 and Ar denotes an unsaturated carbocyclic or heterocyclic group, and the pharmaceutically acceptable salts thereof. These compounds exhibit activity as inhibitors of P-glycoprotein and may thus be used, inter alia, as modulators of multidrug resistance in the treatment of multidrug resistant cancers, for example to potentiate the cytotoxicity of a cancer drug.
Patent CZ-294947-B6 (CZ)
Title: Continuous, compact, concrete, hinged beam with longitudinally variable cross-section shape
Inventor: SETKA KAREL ING
IPC: E04C3/26
Filed: 2003-01-08
Abstract: The present invention relates to a continuous, compact, concrete, hinged beam with longitudinally variable cross-section shape consisting of a row of simple beams (1, 3) having one overhanging end or beams (5) with two overhanging ends and a row of simple beams (2) put on these overhanging ends, optionally on an edge support and on the overhanging end. Said row of simple beams has T or inverted L cross section and at their ends, the cross section continuously enlarges to the full width (14, 16) all over the height thereof. The row of simple beams having one or two overhanging ends has the T or inverted L cross section and at the overhanging ends it has either T or inverted L or rectangular cross section with constant or variable height (17) and at the ends and in supported regions thereof the cross section continuously enlarges to full width (14, 16, 17) all over the height thereof. The beams can be provided with claws (24), side brackets (26) and side brackets (26) with recesses.
Patent CZ-286461-B6 (CZ)
Title: Machine for treating track ballastway
Inventor: THEURER JOSEF ING
IPC: E01B27/11
Filed: 1996-08-26
Abstract: The invented machine (1) for treating track (3) ballast bed (2) is provided with a machine frame (5) being mounted on bogies (9), a sucking unit (14) being adjustable for height and sides and having a suction adapter (19) with a suction opening (20) for sucking-off ballast and a conveyor belt (23) assigned to the suction unit (14) for transporting away the sucked-in ballast a ballast throw-aside mechanism (30) that is arranged in working direction behind the suction adapter (19) and having a hopper (31), as well as a track (3) lifting unit (39). In the machine (1) longitudinal direction there is arranged a transport equipment (33) having a loading end (34) being assigned to the suction unit (14) and a throw-aside end (35) being assigned to the ballast throw-aside mechanism (30) hopper (31), whereby the track (3) lifting unit (39) is arranged between the suction opening (20) and the ballast throw-aside mechanism (30).
Patent CZ-289679-B6 (CZ)
Title: Double-acting ball piston pump
Inventor: HRANAC KAREL
IPC: F04B35/00
Filed: 1998-09-25
Abstract: The invented double-acting ball piston pump provided with an external oscillatory drive /1/ of a ball-type swinging piston /3/ comprises a left half /4/ of a pump casing that is provided with suction holes /5/ and delivery holes  /6/ connected with distribution passages /7, 8/ performed in a right half /9/ of the pump casing, which is fixedly coupled with a pump driving section /10/ by means of through bolts /11/ and binding screws  /12/, whereby in the left half /4/ of the pump casing there is centrally mounted on a sliding ball seat /84/ the ball-type swinging piston /3/. The piston /3/ is coupled by means of a pin /13/ and stud bolts /17/ with a plane bearing /20/ via a central connecting pin /18/ and assembly centering part /19/. Said pin /13/ has a lubricating hole /14/ that is connected to both a lubricating distribution circuit /15/ of the sliding ball seat /84/ and a lubrication hole /28/ of a binding screw /16/ with a lubricator /23/. The plane bearing /20/ has a labyrinth packing /21/ and an axial bearing /22/ of the external oscillatory drive /1/ of the pump driving section /10/ being provided with a rotor /24/ having a bearing mounting /25/ inclined under an angle ({alpha}1) and a sunk counterbalance /26/. The rotor /24/ shaft /27/ is carried in a radial bearing /29/ and a thrust bearing /30/ and sealed by packings /31, 32/. The double-acting ball piston pump is provided with an internal oscillatory drive /2/ of the ball-type swinging piston /3/ in the left half /4/ of the pump casing and in the right half /9/ of the pump casing that halves are coupled with each other my mans of binding bolts /62/. It is formed by a through shaft /33/ carried in bearings /34, 35/ being provided in its grooved section /36/ with a driving cam /38/ of the internal oscillatory drive /2/, whereby the cam /38/ is inclined by an angle ({alpha}2) and locked in axial direction by an adjusting screw /37/. The cam /38/ is further carried on both sides in thrust bearings /39, 40/ in the left half /41/ and the right half /42/ of the ball-type swinging piston /3/, whereby the through shaft /33/ with a driving key-slot /43/ is provided with packings /44, 45/ and secured centrally with respect to the pump vertical axis /46/ by a distance ring /47/. In axial direction the shaft /33/ is secured by a binding screw /48/ having a lubricator /23/ and being provided with a lubrication hole /49/ connected to a lubricating distribution circuit /50/ of the through shaft /33/ and the grooved section /36/  thereof, and a cover /51/ fastened via a radial bearing /34/.
Patent SK-285048-B6 (SK)
Title: Heterocyclic azahexane derivatives, process of their preparation, pharmaceutical composition containing thereof and their use
Inventor: FASSLER ALEXANDER
IPC: C07C233/21
Filed: 1997-04-14
Abstract: There are described compounds of formula (I) wherein R1 is C1-C7alkoxycarbonyl, R2 is secondary or tertiary C1-C7alkyl or C1-C7alkylthio-C1-C7alkyl, R3 is phenyl that is unsubstituted or substituted by one or more C1-C7alkoxy radicals, or C4-C8cycloalkyl, R4 is phenyl or cyclohexyl each substituted in the 4-position by unsaturated heterocyclyl that is bonded by way of a ring carbon atom, has from 5 to 8 ring atoms, contains from 1 to 4 hetero atoms selected from nitrogen, oxygen, sulfur, sulfinyl, sulfonyl and is unsubstituted or substituted by C1-C7alkyl or by phenyl-C1-C7alkyl, R5, independently of R2, has one of the meanings mentioned for R2, and R6, independently of R1, is C1-C7alkoxycarbonyl, or salts thereof, provided that at least one salt-forming group is present. There are described process of their preparation, a pharmaceutical composition containing thereof and use them as inhibitors of retroviral aspartate protease.
Patent SK-282500-B6 (SK)
Title: Vaccine composition containing polyribosylribitol phosphate and its preparation method
Inventor: ARMINJON FRANCOIS
IPC: A61P37/04
Filed: 1996-05-24
Abstract: Vaccine composition containing at least one antigen created by high molecular weight capsular polysaccharide of the influenza Haemophilus influenza of the type b or polyribosylribitol phosphate condensed to the tetanus toxoid as well as adjuvant on the base of aluminium consists of that the adjuvant on the base of aluminium has in its natural state or after adding the anion pH the point of zero charge lower than approximately 7.2. Disclosed is also preparation method of such vaccine composition.
Patent SK-280291-B6 (SK)
Title: Crystalline acid addition salts of both diastereomers of the 1-(2,2-dimethylpropionyloxy)-ethylester of 3-cephem-4-carboxylic acid, process for their preparation, their use, pharmaceutical preparations them containing
Inventor: DEFOSSA ELISABETH
IPC: C07D501/34
Filed: 1992-05-22
Abstract: The invention relates to crystalline acid addition salts of the two diastereomers of the 1-(2,2-dimethylpropionyloxy)ethyl ester of 3-cephem-4-carboxylic acid of the general formula (II) in which X represents the anion of a physiologically acceptable, mono- or polybasic, inorganic or organic acid selected from the group containing HCl, HBr, H2SO4, methanesulfonic acid, ethanesulfonic acid, benzenesulfonic acid, p-toluenesulfonic acid, 4-ethylbenzenesulfonic acid and 4-biphenylsulfonic acid as well as the group =N-OH is in the syn position.
Patent SK-278931-B6 (SK)
Title: Brake disc and method for producing same
Inventor: HEINRICH PETER
IPC: C23C4/129
Filed: 1992-07-08
Abstract: The break wheel (1), described in this patent, is created based on the system which has the internal, stationary metal supporting grid (2) or any other similar component, the bars of which (3, 4) are equipped with the abradability resistant layer (5), while the remaining intermediate spaces (6) closed to the supporting grid (2), are filed by light metal and this filling is provided based on the teeming, as for instance. The abradability resistant layer (5) on the supporting grid (2) consits of the layer sprayed based on the thermic spraying which is a suitable procedrue for these approvals.
Patent CZ-298680-B6 (CZ)
Title: Combined pharmaceutical composition for reducing hyperglycemia and stabilizing the level of serum glucose
Inventor: MCCARTY MARK F
IPC: A61K33/24
Filed: 1998-07-31
Abstract: The present invention relates to the use of synthetic chromic tripicolinate in an amount providing between about 50 and 1,000 micrograms per day of chromium in combination with between about 25 micrograms and 200 micrograms per day of biotin for reducing hyperglycemia and stabilizing the level of serum glucose in an individual.
Patent CZ-296860-B6 (CZ)
Title: Process for preparing ramipril
Inventor: STEPANKOVA HANA
IPC: C07D209/52
Filed: 2004-06-08
Abstract: In the present invention, there is disclosed a process for preparing ramipril of the general formula I, in which benzyl ester hydrochloride of the general formula III is converted to a benzyl ester of the general formula II, which then provides through a reaction with carboxy anhydride of the general formula V a ramipril benzyl ester of the general formula IV that is further converted to the ramipril of the general formula I.
Patent CZ-301795-B6 (CZ)
Title: Discharge device for withdrawing molten glass from a chamber for further processing
Inventor: AZK JAROSLAV
IPC: C03B7/00
Filed: 2006-11-20
Abstract: The present invention relates to discharge device (8) for withdrawing molten glass from a chamber (2) for further processing. particularly for ensuring high-quality color accomplishment of a resulting glass strip wherein said device discharge bowl (1) is disposed at least partially in the chamber (2). Said discharge bowl (1) includes magnetic and/or electrically conducting material, while the chamber (2) is provided from exterior with an inductor (3), formed by a tube and arranged for cooling the chamber (2) with a cooling liquid. At the same time, the chamber (2) is further provided with at least one temperature sensor for controlling temperature thereof by induction heating and/or cooling.
Patent CZ-301889-B6 (CZ)
Title: Process for preparing tizanidine hydrochloride
Inventor: HRADIL PAVEL
IPC: A61K31/4164
Filed: 2008-12-18
Abstract: The present invention relates to a process for preparing 5-chloro-4-(2-imidazolin-2-yl-amino)-2,1,3-benzothiadiazole hydrochloride (tizanidine) of the general formula I, wherein the preparation process is characterized in that first tizanidine salt of the general formula I and a carboxylic acid, especially acetate, formate, propionate, hexanoate, monochloroacetate, dichloroacetate, glycolate and ethoxyacetate is prepared as an intermediate and then after acidifying thereof with hydrogen chloride tizanidine hydrochloride is obtained in a high yield and purity.
Patent CZ-309615-B6 (CZ)
Title: A cryogenic geothermal engine
Inventor: Málek Jiří
IPC: F04C29/12
Filed: 2022-05-03
Abstract: A device for converting geothermal energy into mechanical energy contains a ground borehole (1), which contains a filling of the working medium, which circulates in the borehole and changes its gaseous/liquid state. In preferred embodiment, the borehole is supplemented by a deep deepening (1.1) of the borehole. The deepening (1.1) of the borehole is used to increase the power of the engine by transferring heat from greater depths, and contains water as a working medium, which circulates in the deepening and changes the state of water/steam. The geothermal engine also contains a turbine (10), preferably located in the mouth of the borehole, underground near the surface, or, possibly, on the surface. The borehole (1) is equipped with a casing (2) with a channel (3) for the descent of the liquefied working gas into the boiling vessel (6) located at the bottom of the borehole (1). Up into the turbine (10), the working gas flows through a cavity (4) between the inner surface of the casing (2) and the channel (3).
Patent CZ-302475-B6 (CZ)
Title: Substituted fused heterocyclic compounds
Inventor: FUJITA TAKASHI
IPC: C07D521/00
Filed: 1998-10-08
Abstract: In the present invention, there are disclosed novel substituted fused heterocyclic compounds of the general formula wherein Re1 represents a group of the general formula II or III and the general symbols in the formulae I, II, III have specific meanings. These compounds exhibit excellent activity for improving insulin resistance, lipid-peroxide-production inhibitory action, 5-lipoxygenase inhibitory action and the like. They can be therefore used for the preparation of pharmaceutical composition pharmaceutical compositions suitable for prevention and treatment of a number of diseases such as cardiovascular diseases, hyperlipidemia, diabetes, arteriosclerosis, inflammatory diseases, cancer and the like.
Patent CZ-290793-B6 (CZ)
Title: Device for controlling warp ends on a weaving machine for producing gauze fabrics
Inventor: DVORAK JOSEF DOC ING CSC
IPC: D03C7/06
Filed: 2000-06-15
Abstract: In the present invention there is disclosed a device for controlling warp ends on a weaving machine for producing gauze fabrics, which device comprises a weaving reed (8) containing lamellas with gaps therebetween, each gap being intended for guiding one pair of warp ends, from which one warp end form a part of the system (16) of stationary warp ends and the other warp end is a part of the system (5) of rotating warp ends. A system (14) of needles (15) with loops (15) for guiding the system (16) of the stationary warp ends is mounted reversibly adjustable in front of the weaving reed (8) in the direction of the warp ends movement during weaving. Said system (14) of needles (15) with loops (15) is coupled with a device for generating reversible motion thereof. Control means (4) of said system (5) of rotating warp ends are situated in front of said system (14) of needles (15) with loops (15) for guiding the system (16) of the stationary warp ends in the direction of the warp ends movement during weaving. Said device for generating reversible motion of the system (14) of needles (15) with loops (15) for guiding the system (16) of the stationary warp ends consists of at least one linear motor (19).
Patent CZ-290911-B6 (CZ)
Title: Stable compositions comprising levosimendan and alginic acid
Inventor: LARMA ILKKA
IPC: A61K9/16
Filed: 1999-04-23
Abstract: In the present invention there are disclosed pharmaceutical preparations comprising levosimendan and alginic acid intended for enhancing stability of  levosimendan in the preparation. Levosimendan is useful for treating congestive heart failure.
Patent CZ-294590-B6 (CZ)
Title: Water-soluble binding agent
Inventor: LOOS FRANCIS JEAN ROGER
IPC: B27K5/00
Filed: 2001-06-08
Abstract: In the present invention, there is disclosed a water-soluble binding agent containing: a) an aqueous dispersion of an acrylic copolymer comprising carboxylic acid and ethylene-urea functionality, having average molecular weight below 200,000 and a Tg less than -15 degC, as calculated from the monomer composition using the Fox equation; and b) a water-soluble complex of a transition metal, preferably zinc. The invention further pertains to a coating composition comprising the above-described binding agent and to a wood substrate coated with such a coating composition.
Patent CZ-300624-B6 (CZ)
Title: Elevator
Inventor: AULANKO ESKO
IPC: B66B11/08
Filed: 2002-06-07
Abstract: In the present invention, there is disclosed an elevator, preferably an elevator without machine room, in which elevator a hoisting machine (6) engages a set of hoisting ropes (3) via a traction sheave (7), said set of hoisting ropes (3) having a load-bearing part twisted from steel wires of circular and/or non-circular cross-section, and in which elevator the hoisting ropes (3) support a counterweight (2) and an elevator car (1) moving on their tracks, characterized in that the weight of the hoisting machine (6) of the elevator is at most about 1/5 of the weight of the nominal load of the elevator, the outer diameter of the traction sheave (7) driven by the hoisting machine (6) of the elevator is at most about 250 mm and the elevator car (1) and the counterweight (2) are suspended on the hoisting ropes of the elevator by means of diverting pulleys.
Patent CZ-302412-B6 (CZ)
Title: Medicament for preventing or treating psychotic disorders
Inventor: PLATA-SALAMAN CARLOS R
IPC: A61K31/325
Filed: 2002-02-21
Abstract: In the present invention, there is disclosed the use of carbamate compound being selected from the group consisting of a compound of the general formulae Ib a Ib in a therapeutically effective amount for the preparation of a medicament intended for the prevention or treatment of psychotic disorders such as schizophrenia, schizophreniform disorders, schizoaffective disorders, delusional disorders, brief psychotic disorders, shared psychotic disorders, psychotic disorders due to a general medical condition, substance-induced psychotic disorders or psychotic disorder not otherwise specified wherein the therapeutically effective amount is from about 0.01 mg/Kg/dose to about 100 mg/Kg/dose.
Patent CZ-305152-B6 (CZ)
Title: Heat-exchange apparatus formed by hollow polymer fibers
Inventor: HORSK MARTIN
IPC: F28F21/06
Filed: 2014-02-13
Abstract: In the present invention, there is disclosed a heat-exchange apparatus arranged between flowing media and formed by hollow polymer fibers, said heat-exchange apparatus heat transfer surface in the heat exchange zone is formed by at least one bundle (3) of hollow polymer fibers, which assume lengthwise, randomly and continuously different and also even opposite direction and are randomly arranged within a space, whereby at each end of the bundle, the fibers are fixed with each other.
Patent SK-285565-B6 (SK)
Title: Granulated product with high content of L-carnitine, tablets and capsules containing the same
Inventor: HASSEN KEN
IPC: A61K9/00
Filed: 2000-03-22
Abstract: Granulated product contains from 92 to 96 % by weight of L-carnitine inner salt, (C2-C6)-alkanoyl L-carnitine inner salt or one of their pharmacologically acceptable salts; and from 4 to 8 % by weight of a granulating/bonding material selected from the group consisting of polyvinylpyrrolidone, hydroxyethylcellulose, hydroxypropylcellulose, hydroxypropylmethylcellulose, hydroxybutylcellulose, polyethyleneglycol, microcrystalline cellulose, cellulose acetate phthalate, methylcellulose, ethylcellulose, polyvinylalcohol, and styrene maleic anhydride, or mixtures of these. The invention also relates to capsules containing the granulated product and to tablets obtained by direct compression of the granulated product.