baber/WOPTO huggingface dataset:
Patent NZ-330743-A (NZ)
Title: A long qt syndrome gene which encodes kvlqt1 and its association with mink
Inventor: KEATING MARK T
IPC: G01N33/50
Filed: 1996-12-20
Abstract: One aspect of the invention relates to the identification of the molecular basis of long QT syndrome. More specifically, the invention has identified that mutated KVLQT1 causes long QT syndrome. The analysis of this gene will provide an early diagnosis of subjects with long QT syndrome. The diagnostic methods comprise analyzing the nucleic acid sequence of the KVLQT1 gene of an individual to be tested and comparing them with the nucleic acid sequence of the native, non-variant gene. Alternatively, the amino acid sequence of KVLQT1 may be analyzed for mutations which cause long QT syndrome. Presymptomatic diagnosis of long QT syndrome will enable practitioners to treat this disorder using existing medical therapy. A second aspect of the invention relates to the realization that KVLQT1 coassembles with minK to form a cardiac potassium channel.; This allows one to assay for drugs which interact with this channel to identify new drugs which are useful for treating or preventing long QT.
Patent NZ-331944-A (NZ)
Title: A polyol mixture of an aromatic amine-starter polyether, a sucrose-started polyether and a propylene glycol-started polyether is used for producing hydrocarbon-blown hard polyurethane foams
Inventor: DIETRICH KARL WERNER
IPC: C08G18/48
Filed: 1997-03-10
Abstract: The description relates to a process for producing hard urethane and possibly urea or isocyanate-group-containing foams in which a hard polyurethane foam is made by reacting a) an aromatic polyisocyanate with b) a polyol component with an average of at least three hydrogen atoms reactive to isocyanates, containing 1) 30 to 80 wt.% of an aromatic amine-started polyether with a molecular weight of 300 to 800 based on 70 to 100 wt.% 1,2-propylene oxide and 0 to 30 wt.% ethylene oxide, 2) 10 to 40 wt.% of an essentially sucrose-started polyether with a molecular weight of 400 to 1000 based on 70 to 100 wt.% 1,2-propylene oxide and 0 to 30 wt.% ethylene oxide, 3) 5 to 30 wt.% of a propylene glycol-started polyether with a molecular weight from 500 to 1500 based on 70 to 100 wt.% 1,2-propylene oxide and 0 to 30 wt.% ethylene oxide, 4) n and/or i-pentane as the blowing agent, 5) water, 6) possible auxiliaries and additives, where the percentage weights of components 1), 2) and 3) amount to 100.
Patent NZ-334286-A (NZ)
Title: A joint replacement prosthesis, top part providing a hemispherical or part hemispherical bearing surface
Inventor: ANDERSON IAIN ALEXANDER
IPC: A61F2/40
Filed: 1997-08-21
Abstract: A joint replacement prosthesis comprises a conical base part 6 and a hemispherical or part hemispherical top part 7 providing a hemispherical or part hemispherical replacement bearing surface having a radius of curvature which is at least half the diameter across the conical base part at the widest point of the conical base part.  The prosthesis is shaped and sized to be a wedge fit in a conical recess 8 formed in the head or neck of a human femur or humerus without removal of all of the neck of the femur or humerus.
Patent NZ-334588-A (NZ)
Title: Flat-type communication cable having several twisted-pair conductors in longitudinal passageways
Inventor: O'BRIEN DOUGLAS
IPC: H01B11/02
Filed: 1997-09-09
Abstract: The specification describes a crescent shaped flat-type cable for carrying frequencies in excess of 4 Mhz.  The cable has a plurality of longitudinally extending conductor passageways positioned side-by-side and preferably at least four passageways such that there are two end longitudinal passageways and a plurality of side-by-side intermediate passageways. Each passageway has a longitudinally extending opening which opens to an adjacent passageway. The twisted pair conductors are loosely located in each of the passageways with not more than one twisted pair conductor being in each passageway. Each twisted pair conductor has a cross-sectional envelope area less than a cross-sectional envelope area of the passageway in which the twisted pair is contained.
Patent NZ-334734-A (NZ)
Title: Vaccine composition comprising alum, a saponin fraction (QS21), a sterol (cholesterol), SUV (liposome forming) and MPL (3-de-O-acylated monophosphoryl lipid A)
Inventor: GARCON NATHALIE
IPC: A61P31/04
Filed: 1997-09-30
Abstract: An adjuvant vaccine formulation containing alum, an antigen, an immunologically active fraction derived from the bark of Quillaja Saponaria Molina (such as QS21) and a sterol (cholesterol). The surprising result was found when alum was incorporated into a vaccine formulation containing MPL, QS21 and SUV that it enhances both humoral and cellular responses. The formulation is also non-toxic with good reactogenicity profile and enhanced adjuvant activity. In addition and more surprising, the combined adjuvant appears to favour TH1 immune responses.
Patent NZ-334895-A (NZ)
Title: Benzamidine derivatives and their use as medicaments with LTB4-antagonistic effect
Inventor: SCHROMM KURT
IPC: C07C257/18
Filed: 1997-09-09
Abstract: The benzamidine derivatives of formula I can be used in medicaments for the treatment of arthritis, asthma, chronic bronchitis, psoriasis, ulcerative colitis, gastropathy or enteropathy induced by nonsteroidal antiinflammatories, cystic fibrosis, Alzheimers disease, shock, reperfusion damage/ischaemia, atherosclerosis and multiple sclerosis. In formula I: A is O-C2-4alkylene-O- or C1-3alkylene-O-; R1 is branched or unbranched C1-6alkyl, branched or unbranched C3-6alkenyl, preferably allyl, or F, Cl, Br, I; R2 is H or the options for R1; R3 and R4 are independently H, branched or unbranched C1-6alkyl, branched or unbranched C3-6alkenyl, preferably allyl, C1-6alkoxy, (C1-4alkyl)OC(O)O, benzloxy, 2-hydroxyethoxy, 2-morpholinoethoxy, Cl, F, OH or CF3, or R3 and R4 together form a fused-on mono- or dinuclear ring system, which may be wholly or partially conjugated, optionally containing O, S or N as a heteroatom(s) and optionally substituted by OH, C1-4alkoxy or C1-4alkyl; R5 is H, or phenyl, O-phenyl, CR7R8-phenyl, C(O)phenyl, SO2phenyl or CH(OH)phenyl, optionally substituted with OH, C1-4alkoxy or C(O)NR9R10; R6 is H, C1-6alkoxycarbonyl or (C1-5alkyl)carbonyl or C(O)O(C1-6alkylene)NR11R12;  R7 and R8 are independently H, branched or unbranched C1-8alkyl  or CF3; and R9, R10, R11 and R12 are independently H or branched or unbranched C1-8alkyl.
Patent NZ-336267-A (NZ)
Title: dye stuff composition containing a dye cake and a sulphonated or sulphomethylated lignin dispersant
Inventor: DILLING PETER
IPC: C09K23/50
Filed: 1999-06-14
Abstract: The dyestuff composition comprises a dye cake and a lignin dispersant. The dye cake is either a disperse dye or a vat dye and the lignin dispersant is either sulphonated lignin or sulphomethylated lignin. The lignin dispersant has a heat stability of no greater than 50 bar oC, a polydispersity value of less than 5 and is essentially free of molecules below a molecular weight of 3,000. Addition to 336267
Patent NZ-337489-A (NZ)
Title: System and method of altering transaction terms based upon current inventory levels
Inventor: GOODWIN JOHN COKER
IPC: G06Q20/20
Filed: 1999-08-30
Abstract: Electronic price labels (EPLs) 22 are associated with rental items to display rental price and period information. Storage medium 36 contains threshold inventory ranges and associated prices and rental periods. PLU terminal 40 is used to determine whether to replace first prices with second prices if the first and second inventory ranges differ.
Patent NZ-337971-A (NZ)
Title: Combustion engine with cylinders and back to back piston pair axes arranged about shaft axis, with axial adjustment of pistons
Inventor: HENRIKSEN LEIF DAG
IPC: F02B75/26
Filed: 1998-04-22
Abstract: A combustion engine (10) comprises a number of engine cylinders (21), which are arranged in an annular series around a common middle drive shaft (11). Each cylinder includes a pair of pistons (44, 45) movable towards and away from each other and a common, intermediate working chamber (K') for each pair of pistons. Each piston (44, 45) is equipped with its piston rod (48, 49) with associated support roller (53) which forms a support against its respective "sine" - curve shaped cam guide device (12a, 12b), which controls movements of the piston relative to the associated cylinder. A least the one (44) of the two pistons (44, 45) in each cylinder (21) is regulatably adjustable axially in the cylinder especially for regulating the compression ratio in the common working chamber (K')
Patent NZ-503294-A (NZ)
Title: Halogen substituted tetracyclic tetrahydrofuran derivatives and pharmaceutical use
Inventor: ANDRES-GIL JOSE IGNACIO
IPC: C07D307/93
Filed: 1998-10-06
Abstract: Compounds of formula (I) may be used in medicaments for the treatment of anxiety, psychosis, schizophrenia, depression, migraine, sleep disorders and addictive properties of drugs of abuse. In formula (I); n is zero, 1, 2, 3, 4, 5 or 6; X is CH2 or O; R1 and R2 each independently are hydrogen, C1-6alkyl, C1-6alkylcarbonyl, halomethylcarbonyl or C1-6alkyl substituted with hydroxy, C1-6alkyloxy, carboxyl, C1-6alkylcarbonyloxy, C1-6alkyloxycarbonyl or aryl; or R1 and R2 taken together with the nitrogen atom to which they are attached may form a morpholinyl ring or radical depicted above, wherein R9, R10, R11 and R12 independently are hydrogen, halo, halomethyl or C1-6alkyl m is 0, 1, 2 or 3; R13, R14, R15 and R16 each independently are hydrogen, C1-6alkyl, aryl or arylcarbonyl; or R15 and R16 taken together may form a bivalent radical C4-5alkanediyl; R17 is hydrogen, C1-6 alkyl, C1-6alkylcarbonyl, halomethylcarbonyl, C1-6alkoxycarbonyl, aryl, di(aryl)methyl or C1-6alkyl substituted with hydroxy, C1-6 alkyloxy, carboxyl, C1-6alkylcarbonyloxy, C1-6alkyloxycarbonyl or aryl; R3 and R4 are both halogen; or R3 is halogen and R4 is hydrogen; or R3 is hydrogen and R4 is halogen; and aryl is phenyl or phenyl substituted with 1, 2 or 3 substituents selected from halo, hydroxy, C1-6alkyl and halomethyl.
Patent NZ-506167-A (NZ)
Title: Travel-related multi-function smartcard having limited write access partner file structure and an open write access common partner file structure
Inventor: HOHLE WILLIAM
IPC: G07B15/02
Filed: 1999-01-21
Abstract: Methods and apparatus for a smartcard system are provided, which securely and conveniently integrate important travel-related applications. In one embodiment, a smartcard system includes a cardholder identification application and various additional applications useful in particular travel contexts; for example, airline, hotel, rental car, and payment-related applications. Furthermore, memory space and security features within specific applications provide partnering organizations (e.g., airlines, hotel chains, and rental car agencies) the ability to construct custom and secure file structures.
Patent NZ-507982-A (NZ)
Title: Human protein C polypeptide
Inventor: HUANG LIHUA
IPC: C12N9/64
Filed: 1999-06-01
Abstract: An isolated human protein C polypeptide comprising SEQ ID NO: 2; use of an isolated activated protein C polypeptide comprising SEQ ID NO: 2 in the preparation of a medicament for treating a condition selected from the group consisting of protein C deficiencies, thrombotic disorders, vascular occlusive disorders and hypercoagulable states in a patient in need thereof, including sepsis, disseminated intravascular coagulation, purpura fulminans, major trauma, major surgery, burns, adult respiratory distress syndrome, transplantations, deep vein thrombosis, heparin-induced thrombocytopenia, sickle cell disease, thalassemia, viral hemorrhagic fever, thrombotic thrombocytopenic purpura, hemolytic uremic syndrome, myocardial infarction, and stroke.
Patent NZ-509943-A (NZ)
Title: Immediate release tablet for low molecular weight peptide based thrombin inhibitors
Inventor: KARLSSON CHRISTER
IPC: A61K31/397
Filed: 1999-08-27
Abstract: An oral immediate release formulation in solid form is disclosed, comprising (a) a low molecular weight peptide thrombin inhibitor having pH dependent solubility and having a particle size of less than 300 microns, and (b) a combination of microcrystalline cellulose and sodium starch glycollate in an amount higher than 35% w/w of the formulation.
Patent NZ-510369-A (NZ)
Title: Use of heteroaryl substituted N-(indole-2-carbonyl-) amides for treatment of infection
Inventor: SUTCLIFFE JOYCE ANNE
IPC: A61P31/00
Filed: 2001-03-06
Abstract: Use of glycogen phosphorylase inhibitors of formula (I) or (Ia) for treating or preventing infections such as bacterial, fungal, parasitic, or viral.
Patent NZ-512477-A (NZ)
Title: Triazineone compounds for treating diseases due to sarcosystis, neospora and toxoplasma
Inventor: KENNEDY THOMAS J
IPC: C07D251/38
Filed: 1999-12-18
Abstract: A method of therapeutically treating a diseased non-human animal suffering from an parasitic neurologic or abortigenic disease which is susceptible to being treated with ponazuril (a triazineone compound). The parasitic disease may come from the family of Sarcocystis, Neospora and Sarcocystidae
Patent NZ-514799-A (NZ)
Title: Video surveillance event recording system based on video motion detection using a video camera with a VCR or DVD recorder
Inventor: NOUROZI FRASHAD
IPC: H04N17/06
Filed: 2001-10-16
Abstract: Surveillance means for an area comprises a video signal source means (2) and control means (1), the video signal source means (2) is capable of producing a video signal (3) and the control means (1) is capable of monitoring the video signal and detecting a movement condition (9) in the video signal, the control means is capable of sending a wireless record signal in response to the movement condition (9) being detected by the control means (1), the record signal is capable of causing a video recording means (5) to make a video recording of the area when the surveillance means is in use.
Patent NZ-517485-A (NZ)
Title: Use of bis-sulfonamides for producing medicaments used for preventing or treating hyperlipidaemia
Inventor: KRASS NORBERT
IPC: A61K31/40
Filed: 2000-08-17
Abstract: Disclosed is the use of bis-sulfonamides, and of their physiologically compatible salts and physiologically functional derivatives for producing medicaments used for preventing or treating hyperlipidaemia. The use of compounds of formula (I), wherein the radicals have the cited meanings, and the use of their physiologically compatible salts and physiologically functional derivatives for producing a medicament used for preventing or treating hyperlipidaemia or arteriosclerosis.
Patent NZ-518228-A (NZ)
Title: Floor waste assembly with drain channel formed between tile and supporting recessed structure
Inventor: REED SELWYN
IPC: E03F5/042
Filed: 2002-04-05
Abstract: A support member 2 is located in a floor structure upon which tile 3 is located. In use, waste water passes between the tile 3 and member 2 to outlet pipe 8.
Patent NZ-522236-A (NZ)
Title: A compact diversity (multiple directional) antenna to mitigate the effects of multi-path propagation
Inventor: MCCONNELL DOUGLAS ANDREW
IPC: H04B7/02
Filed: 2002-10-25
Abstract: An antenna (20) for telecommunication equipment includes one or more electromagnetically shielded sections (24a, 24b, 24c), each section includes a driven element (W) and one or more reflectors (22a, 22b, 22c), wherein the maximum dimension of the reflector perpendicular to the element is 0.2 ë, where ë is the antenna operating wavelength, wherein the antenna elements and sections are arranged for use as a diversity antenna and the shielded sections are formed from one or more reflector plates (22a, 22b, 22c),.
Patent NZ-522818-A (NZ)
Title: Method used for transforming the carbonyl function in position 4" of a cladinose unit of an aza macrolide into an amine derivative
Inventor: DHAINAUT JILDAZ
IPC: C07H17/08
Filed: 2001-05-09
Abstract: Disclosed is a process for preparing a compound of formula (I), in which: R is a hydrogen atom or an optionally substituted C1-C10 alkyl, C2-C10 alkenyl or C6-C12 arylsulfonyl group; and R1 and R2 which may be identical or different, represent a hydrogen atom, or a C1-C10 alkyl group substituted with one or more optionally substituted aryl groups, or an optionally substituted C6-C12 aryl group; said process comprising a reductive amination compound of formula (II): in which: R is as defined in the formula (I); and P represents a hydrogen atom or a protecting group; wherein said reductive amination comprises: contacting the compound of formula (II) with at least one nitrogenous reagent and an aprotic Lewis acid to form a reaction medium; and reducing the reaction medium using a reducing agent.
Patent NZ-524248-A (NZ)
Title: Spray device
Inventor: LANGFORD ALAN
IPC: B65D83/14
Filed: 2001-08-15
Abstract: The present invention relates to a spray device (e.g., an inhaler) comprising an aerosol formulation administered to the respiratory or nasal tract in which the level of formulation remaining in the device can be readily inspected. The device comprises a glass vial (1) coated with a coating of polymeric material having at least one clear or translucent portion (4).
Patent NZ-524974-A (NZ)
Title: Aliphatic nitrogen-containing 5-membered ring compound
Inventor: YASUDA KOSUKE
IPC: A61P43/00
Filed: 2001-10-05
Abstract: Disclosed are aliphatic nitrogen-containing 5-memebered ring compounds of formula (I), wherein: A is -CH2- or -S-, R1 is H, lower alkyl, hydroxy lower alkyl, or lower alkoxy lower alkyl, X is -N(R3)-, -O- or -CO-, and the remaining substituents are defined herein. The compounds are used in the manufacture of medicaments for the treatment of diseases mediated by inhibiting dipeptidylpeptidase IV activity.
Patent NZ-525546-A (NZ)
Title: Tube coupling with open-ended cap engaging with hollow body with combined rotational/axial movement to lock tube(s) to coupling
Inventor: GUEST JOHN DEREK
IPC: F16L37/092
Filed: 2003-04-29
Abstract: A tube (not shown) is held within the coupling assembly by a cap 35 being moved so that ramp 24 moves over ramp 30. The cap 35 is then rotated so that combined axial and rotational movement seals and locks the tube. Typically, seal 50, ring member 60 and collet 23 is provided and typically two tubes are connected via the coupling with parts 35, 50, 60 and 23 provided at each end of the coupling.
Patent NZ-526724-A (NZ)
Title: Dispensing apparatus
Inventor: GUERRERA ANGELO
IPC: B05C17/005
Filed: 2001-12-21
Abstract: Disclosed is a dispensing apparatus (1) that includes the combination of a tube (2), cap (4) and plunger (3). The tube is arranged for carrying a collapsible sausage (6) and includes longitudinally extending ribs (8) projecting inwardly of the tube and defining longitudinal grooves (7) therebetween, the grooves having an annular dimension (A) greater than the distance (B) between adjacent ribs. The cap includes: a coupling portion (20) for mounting the cap to the tube; an outlet (21) through which contents of the collapsible sausage carried within the tube are dispensed; and a chamber (22) into which the sausage is adapted to be collapsed under action of the plunger within the tube. The plunger itself has a main body (11) with radial fins (10) projecting therefrom for receipt in the grooves of the tube, between adjacent ribs, the fins being dimensioned to engage lateral edges of the ribs, in a point contact manner.
Patent NZ-527531-A (NZ)
Title: Low formaldehyde emission panel
Inventor: BELMARES HECTOR
IPC: D04H1/64
Filed: 2003-08-12
Abstract: Describes panel comprising: a substrate having a facing side and a backing side; and a scrim attached to the facing side by a polymeric adhesive, the adhesive including about 15% to about 70% by weight of a copolymerized non-hydrolysable, hydrophobic monomer and about 1% to about 20% by weight of a formaldehyde scavenger.
Patent NZ-528291-A (NZ)
Title: Drugs containing chymase inhibitor and ace inhibitor as the active ingredients
Inventor: URATA HIDENORI
IPC: A61K45/06
Filed: 2002-08-26
Abstract: Disclosed is the use of a chymase inhibitor as an effective ingredient in the manufacture of a medicament for the prophylaxis or treatment of cardiac disease, arteriosclerosis, nephritis or renal failure wherein said chymase inhibitor is a compound represented by formula (I) wherein the substituents are as described in the specification.
Patent NZ-529455-A (NZ)
Title: A centrifugal compressor wheel associating a composite material structure and a metal structure, and a method of manufacture
Inventor: GODICHON ALAIN FRANCOIS EMILE
IPC: F04D29/28
Filed: 2002-10-03
Abstract: A centrifugal compressor wheel made of composite material and metal which possesses improved ability to withstand angular deformation is described. The wheel consists of a metallic hub 2 designed to be linked to a drive shaft, two circular plates 4,5 between which are fixed a series of blades 7. The wheel includes an annular metallic insert 8 which is integrated in the central part of the wheel at the periphery of the hub 2, and which includes metallic elements 7A forming the initial part of the wheel blades. The circular plates and the remaining and peripheral part 7B of the vanes are made of a composite material to form the composite part of the wheel.
Patent NZ-530290-A (NZ)
Title: Specific cyclolignans for treating insulin-like growth factor-1 receptor dependent diseases
Inventor: LARSSON OLLE
IPC: C07D317/54
Filed: 2002-06-19
Abstract: Use of specific cyclolignans for treating insulin-like growth factor-1 receptor (IGF-1R) dependent diseases by inhibiting the insulin-like growth factor-1 receptor is disclosed, wherein the carbon atoms in positions 9 and 9' of these cyclolignans have cis configuration. Specific cyclolignans such as picropodophyllin can be used for the treatment of IGF-1R dependent diseases, such as cancer, psoriasis, artherosclerosis and acromegaly.
Patent NZ-533269-A (NZ)
Title: Inhibitors of cytosolic phospholipase A2
Inventor: MCKEW JOHN CAEDMON
IPC: A61P29/00
Filed: 2002-12-02
Abstract: Disclosed are compounds of formula (I), wherein: R is -(CH2)n-A, -(CH2)n-S-A, or -(CH2)n-O-A, and the remaining substituents are defined herein. Also disclosed are intermediate compounds of formula (A). The compounds of formula (I) are used in the manufacture of medicaments for the treatment of inflammation, pain, asthma or arthritic and/or rheumatic disorders in a mammal.
Patent NZ-534522-A (NZ)
Title: Anti-amyloid beta antibodies and their use
Inventor: BARDROFF MICHAEL
IPC: A61K39/00
Filed: 2003-02-20
Abstract: Disclosed are antibody molecules capable of specifically recognizing two regions of the R-A4 peptide, wherein the first region comprises the amino acid sequence AEFRHDSGY as shown in SEQ ID NO: 1 or a functional fragment thereof and wherein the second region comprises the amino acid sequence VHHQKLVFFAEDVG as shown in SEQ ID NO: 2 or a functional fragment thereof and wherein said antibody molecule comprises a variable V1-region comprising the complementary determining regions L-CDR1, L-CDR2 and L-CDR3 and/or a variable VH-region comprising the complementary determining regions H-CDR1, H-CDR2 and H-CDR3 as defined herein. Nucleic acid molecules encoding the antibody molecules and vectors and hosts comprising said nucleic acid molecules are also disclosed, as well as compositions comprising the antibody molecules, nucleic acid molecules and vectors or hosts.