baber/WOPTO huggingface dataset:
Patent CA-1312567-C (CA)
Title: Yeast strains with reduced intracellular atp levels
Inventor: ROGERS DAVID T
IPC: C07H21/04
Filed: 1986-11-07
Granted: 1993-01-12
Abstract: Abstract The present invention provides a process for increasing the rate of production of carbon dioxide, ethanol and other fermentation products such as citric acid, produced by yeast such as Saccaromyces cerevisiae during fermentation and decreasing biomass production by regulating the rate of glycolysis indirectly through changing the energy balance of the cell, i.e. by reducing intracellular ATP levels.          Modifications for so altering the glycolysis rate involve the use of either a regulated ATP hydrolysis within the cell or a regulated leakage of ATP from the cell. This invention encompasses several ways for altering the yeast ATP level including (a) engaging futile metabolic cycles to increased ATP consumption; (b) using an altered exocellular acid phosphatase so that it becomes intracellular to increase intracellular ATP hydrolysis; (c) using a drug which uncouples the plasma membrane ATPase thereby consuming an abnormally high level of ATP; and (d) using a drug which allows the release of ATP from the cell to lower the intracellular ATP level.          This invention further encompasses regulating the genetic modifications described in greater detail herein. By these means, such modifications may be turned off during growth of the yeast on a commercial scale, and then turned on before or during, and preferably before or at a very early stage of, the dough-rising phase.
Patent CA-1282701-C (CA)
Title: Rumen-stable pellets
Inventor: WU STEPHEN H
IPC: A23K1/00
Filed: 1986-11-18
Granted: 1991-04-09
Abstract: Rumen-Stable Pellets Abstract Disclosed are rumen-stable compositions for coating medicaments and nutrients for ruminant animals.  The coatings comprise a film-forming polymeric substance containing basic nitrogen groups, and an inorganic particulate material dispersed throughout the polymeric substance.
Patent CA-1304340-C (CA)
Title: Pulley for extension cord reel
Inventor: KOVACIK JAMES D
IPC: B65H75/14
Filed: 1986-11-28
Granted: 1992-06-30
Abstract: ABSTRACT A pulley for use in storing an electrical extension cord includes a pulley body having a generally tubular cord winding body with a radially outwardly extending flange formed at one end of its exterior surface.  A generally disk-shaped flange plate is releasably attached to the other end of the winding body by locking tabs formed on the winding body which cooperate with apertures formed in the flange plate.  Typically, the pulley body is formed of a nylon material and the flange plate is formed of steel. The winding body includes an internal wall and an aperture is formed in the wall and another aperture is formed in the flange plate for rotatably mounting the pulley on a supporting shaft.  A coil spring has one end attached to the shaft and the other end attached to the winding body for automatically rewinding the extension cord.
Patent CA-1293251-C (CA)
Title: Pyrazine derivative, a process for preparation thereof and pharmaceutical composition therefrom
Inventor: ITOH YASUO
IPC: C07D403/14
Filed: 1986-12-18
Granted: 1991-12-17
Abstract: ABSTRACT OF THE DISCLOSURE       The present invention relates to derivatives of pyrazine represented by general formula   wherein R represents hydrogen atom or     , wherein R1 and R2 which may be the same or different, represent hydrogen atom, straight or branched-chain lower alkyl  group or cycloalkyl group having 3 to 6 carbon atoms, phenyl group, which may be substituted with halogen, lower alkyl group or lower alkoxyl group, or 5 to 7 membered-ring together with the neighborous nitrogen atom, which may have oxygen atom, nitrogen atom or sulfur atom as ring-member and may be substituted with substituent, and pharamacuetically-acceptable salts thereof.          The compounds of the invention are useful for treatment of bronchial asthma, allergic gastroenteric trouble, hay fever urticaria, allergic rhinitis and allergic conjunctivitis.                                  .
Patent CA-1295620-C (CA)
Inventor: DRESSLER HANS
IPC: C10M137/02
Filed: 1987-01-05
Granted: 1992-02-11
Abstract: ABSTRACT        Alkylresorcinol phosphites useful as antioxidants in lubricants and greases are provided of the formula:       wherein R is selected from H and alkyl, and R1 is an alkyl, said alkyls being the same or different having from 8 to 18 carbon atoms and consisting of at least 75% secondary alkyl.
Patent CA-1290964-C (CA)
Title: Pivoting optical accessory for use with spectacles
Inventor: GAZELEY ALBERT E
IPC: G02C9/04
Filed: 1987-03-20
Granted: 1991-10-22
Abstract: Title:  PIVOTING OPTICAL ACCESSORY FOR USE WITH SPECTACLES                ABSTRACT OF THE DISCLOSURE There is disclosed an improved optical accessory of the sun shade type for use with a pair of prescription spectacles.  The accessory includes releasable securing structure which releasably cooperates with a bridge assem-bly of the spectacles to inhibit movement of the accessory relative thereto and further includes structure which permits pivoting of the accessory's sun shades.
Patent CA-1309291-C (CA)
Title: Processing of exposed lithographic printing plates
Inventor: GARTH PETER
IPC: G03F7/38
Filed: 1987-04-02
Granted: 1992-10-27
Abstract: ABSTRACT           The invention relates to an automatic machine for the reversal processing of lithographic printing plates which are required to be exposed overall after heating.  The method and apparatus of the invention provide that the exposure be effected while the plates are being conveyed through water in a shallow bath.
Patent CA-1286923-C (CA)
Inventor: BALLANTYNE RONALD
IPC: B66D1/72
Filed: 1987-05-12
Granted: 1991-07-30
Abstract: C A N A D A     INVENTION: MECHANISM FOR TENSIONING A MOVING CHAIN               INVENTOR: RONALD BALLANTYNE                ABSTRACT OF THE DISCLOSURE In an anchoring system for a floating vessel which includes an anchor line comprising chain cable, a chain locker and a windlass having a chain wheel that conveys the chain cable during paying out from the chain locker, a mechanism is positioned between the chain locker and chain wheel to back-tension the chain during paying out. The mechanism has an axis along which the chain is passed with everysecond links oriented in a given plane. Paired brake shoes are positioned to either side of the plane and define braking surfaces of sufficient extent along the axis of chain movement that a given chain link and an immediately succeeding link of similar orientation can be simultaneously engaged during their movement to provide a continuous retarding effect. One pair of braking shoes is pivotally mounted on an appropriate support structure and urged with hydraulic cylinders towards the other pair thereby causing the brake shoes to engage the opposing faces chain link. The pressure of hydraulic fluid applied to the cylinders is adjusted to back-tension the chain sufficiently that sudden shocks to the windlass otherwise occasioned by tilting and jumping of chain links during conveyance over the chain wheel are avoided Non-standard links and irregularites in the chain link surfaces such as weld lines are accommodated by contraction of the hydraulic cylinders and deflection of the pivoting brake shoes.
Patent CA-1298303-C (CA)
Title: Process for the stereospecific synthesis of indole derivatives
Inventor: WAGNON JEAN
IPC: C07D413/06
Filed: 1987-06-30
Granted: 1992-03-31
Abstract: IN THE UNITED STATES PATENT & TRADEMARK OFFICE PATENT APPLICATION entitled:  Process for the stereospecific synthesis of indole derivatives in the names of:  Jean WAGNON                   Claude PLOUZANE Bernard TONNERRE Dino NISATO Assignee:  SANOFI              ABSTRACT OF DISCLOSURE      The present invention relates to a process for the stereo-specific synthesis of indole derivatives of formula :                            (I) which consists in using 3-tosyloxy-1,2 0-isopropylidenepropane-1,2 -diol in an optically pure form in order to introduce the asymetric carbon C* of the compound (I).
Patent CA-1289296-C (CA)
Title: Low viscosity, semicrystalline chlorinated polyethylene resinsand articles formed therefrom
Inventor: STEPHENS KEITH E
IPC: B32B27/32
Filed: 1987-07-10
Granted: 1991-09-17
Abstract: Abstract of the Disclosure Chlorinated polyethylene resins which are semicrystalline yet of sufficiently low viscosity to be processible on conventional extrusion equipment are provided.  The resins may be used in a variety of applications such as membranes, either theromplastic or thermoset, wire and cable jackets and the like. Plasticizers and other viscosity-reducing aids need not be used in conjunction with these resins. 35,141-F
Patent CA-1318785-C (CA)
Title: Method and apparatus for drying wet particulate material to a predetermined uniform moisture content
Inventor: SPADAFORA PAUL F
IPC: F26B25/22
Filed: 1987-07-21
Granted: 1993-06-08
Abstract: Abstract of the Disclosure In a fluidized bed drying process, the average temperature of a group of particles being dried rises during a warm-up zone, remains constant during a constant-temperature drying zone and again increases during a final zone.  In order to maintain the moisture content of the product at the output of the oven at a substantially constant level despite variations in the moisture content at the inlet to the oven, the temperature and/or flow rate of the drying air to the oven is varied in accordance with measured differences in the temperature of the group of particles at two instants in time during the drying process.  At least one of the instants occurs during the warming-up zone or during the final temperature-increasing zone.
Patent CA-1284685-C (CA)
Title: Indoor telephone network interface device
Inventor: CRANE ROBERT A
IPC: H04Q1/02
Filed: 1987-08-20
Granted: 1991-06-04
Abstract: Abstract of the Invention A telephone network interface device adapted to be placed within a standard receptacle box including a face plate and a housing containing terminal posts dis-posed on the rear of the housing.  A cover is detach-ably arranged over an array of terminal posts that are adapted to be connected to the telephone company's por-tion of the telephone network and terminal posts are exposed for subscriber access to the portion of the posts that are connected to the subscriber's portion of the telephone system.
Patent CA-1304261-C (CA)
Title: Thermally insulated window sash construction for a casement window
Inventor: BIRO ALEXANDER J
IPC: E04C2/38
Filed: 1987-08-27
Granted: 1992-06-30
Abstract: Abstract A  window  sash  member  includes  first  and  second generally  parallel   sidewalls.   First   and   second   spaced, generally  parallel  transverse  walls,  extending  between  and oriented  generally  perpendicular  to  the  first  and  second sidewalls, connect the first and second sidewalls to define a first hollow chamber. A third transverse wall, located without the first hollow chamber adjacent to and generally parallel to the first transverse wall,  extends from the first transverse wall  and  terminates  short  of  the  second  sidewall.  A  first interior  wall,  oriented  generally  parallel  to  the  first sidewall, extends from the third transverse wall to the first transverse wall to define  a second hollow chamber.  A fourth transverse  wall,  located  without  the  first  hollow  chamber adjacent  to  and generally parallel  to  the  second  transverse wall, extends from the first sidewall and terminates short of the second sidewall. A second interior wall, oriented generally parallel  to  the  second  sidewall,  extends  from  the  fourth transverse wall to the second transverse wall to define a third hollow chamber. A window sash employs at least one of such sash members.
Patent CA-1278735-C (CA)
Title: Tread splicer
Inventor: REX WILLIAM A
IPC: B29C65/00
Filed: 1987-10-09
Granted: 1991-01-08
Abstract: ABSTRACT OF THE DISCLOSURE                        TREAD SPLICER          A tread splicer (10) including two rows (60,64) of splicing blade assemblies (68) mounted with the blades (76) of one row (60) tilted toward and overlapping the blades  (76)  of the other row (64).   Each of the blade assemblies (68) is operable independently to control the pressure applied to selected portions of the tread ends. Guide rollers (54,56,58) on the tread splicer (10) pro-vide stitching of the tread (14) as well as positioning of the blades  (76) relative to the tread (14) and tire building machine drum (18).
Patent CA-1279455-C (CA)
Title: Injection molding press
Inventor: SONODA TAKEFUMI
IPC: B29C45/46
Filed: 1987-10-29
Granted: 1991-01-29
Abstract: ABSTRACT      In an injection molding press of the present invention, a plunger is inserted into a barrel and a material inlet is provided on the rear side of the barrel.   A valve seat is provided in the inner periphery of the barrel and a valve body which can be brought into contact with the valve seat is provided on the end of the plunger.   In addition, a lengthwise moving unit is aligned with the plunger and, when the plunger is moved lengthwisely, a portion having increasing diameters is brought into contact with a portion having decreasing diameters so that a material passage is opened and closed.   A sleeve is engaged in the end of the barrel in such a manner that it can slide in the axial direction of the barrel and has an injection hole at one end. A lengthwise barrel-moving unit is provided on the barrel or the plunger.   After a material has been stored in the barrel, the barrel is moved forward so that the material is injected from the injection hole into a mold.
Patent CA-1285102-C (CA)
Title: Tibial prosthesis
Inventor: WEVERS HENK W
IPC: A61F2/38
Filed: 1987-11-06
Granted: 1991-06-25
Abstract: ABSTRACT          An improved tibial plateau prosthesis is described in which a baseplate  is anatomically peripherally shaped and provided with a knife edge perimeter which cuts into the soft tissue outer edge of the epiphyseal shell of the tibia and effectively caps the tibia.  Hoop stresses are reduced, and the use of wrought metal for the baseplate, inclusion of a deep intercondylar cut out as well as a series of performations at locations corresponding to positions of hardness of the cancellous bone facilitates flexibility more in tune with the properties of the original subchondral bone plate and cartilage which in turn reduces "lift-off" from an unloaded condyle during loading of the other condyle.  Bone ingrowth is encouraged by accurate flat cutting and the provision of the perforations.          Initial stability is promoted by the knife edge and its asymmetrical circumferential shape.
Patent CA-1331770-C (CA)
Title: Molded case circuit breaker contact arrangement
Inventor: MORRIS ROBERT A
IPC: H01H1/58
Filed: 1987-12-17
Granted: 1994-08-30
Abstract: MOLDED CASE CIRCUIT BREAKER CONTACT ARRANGEMENT                 ABSTRACT OF THE DISCLOSURE      A molded case circuit breaker movable contact arm or carrier electrically connects with the circuit break-er trip unit or load terminal without requiring a flex-ible electrical conducting braid.  The contact carrier is pivotally arranged within a contact carrier support to which the trip unit or load terminal lug is attached. The contact carrier pivot pin is supported on a pair of parallel posts extending from the contact carrier and a spring clip is positioned around the parallel posts and the pivoting end of the contact carrier to promote good electric transport without interfering with the rota-tional movement of the contact carrier.
Patent CA-1309561-C (CA)
Title: Retanning process
Inventor: KAUSSEN MANFRED
IPC: C14C3/22
Filed: 1988-01-21
Granted: 1992-11-03
Abstract: Abstract The present invention relates to a process to improve the organoleptic behaviour and the physical characteristics of leather by the use of aqueous solutions of copolymers of 90 to 20%-wt acrylic acid or methyacrylic acid, as well as 10 to 80%- wt of a monomer of the formula   wherein R1 is hydrogen or methyl; R2 and R3, which are equal or different, are methyl or ethyl; x stands for an optionally branched alkylene radical with 1 to 5 carbon atoms; the amine nitrogen is optionally neutralized or quaternized;  and the molecular weight of the copolymer, measured at a pH of 8.0, is less than 100,000.  The concentration of the copolymer in the aqueous solution is 0.02 to 10%-wt. relative to the shaved weight of the leather.
Patent CA-1278787-C (CA)
Title: Rotary valve
Inventor: AHRENS ROBERT H
IPC: F16K7/18
Filed: 1988-02-05
Granted: 1991-01-08
Abstract: ROTARY VALVE              Abstract of the Disclosure A valve in which a rotary valve member includes rollers which support two endless belts to roll along the cylindrical wall of a valve housing as the valve member is opened and closed.  The belts seal tightly against the wall and close off inlet and outlet ports when the valve member is in its closed position.
Patent CA-1314553-C (CA)
Title: Bicyclic compounds, processes for preparation thereof and pharmaceutical composition comprising the same
Inventor: OKU TERUO
IPC: C07C231/12
Filed: 1988-04-27
Granted: 1993-03-16
Abstract: A B S T R A C T         Bicyclic  compounds  and  pharmaceutically acceptable salts thereof which can be represented by the following general formula:                        wherein A is    or    , R1 is aryl which may have cyano or carbamoyl, or heterocyclic group which may have lower alkyl, R2 is hydrogen or lower alkyl, R3 is lower alkyl, X is hydrogen, halogen, hydroxy or lower alkyl, m is an integer 1 or 2, and n is an integer 1 to 4, and pharmaceutically acceptable salts thereof. These compounds and their salts have 5-lipoxygenase-inhibiting activity.  Processes for the preparation of these compounds and compositions containing them are also disclosed.
Patent CA-1341415-C (CA)
Title: Targeted multifunctional proteins
Inventor: OPPERMANN HERMAN
IPC: C07K19/00
Filed: 1988-05-20
Granted: 2003-01-07
Abstract: Disclosed are a family of synthetic proteins having binding affinity for a preselected antigen, and multifunctional proteins having such affinity.      The proteins are characterized by one or more sequences of amino acids constituting a region which behaves as a biosynthetic antibody binding site (BABS). The sites comprise V H-V L or V L-V H-like single chains wherein the V H and V L-like sequences are attached by a polypeptide linker, or individual V H or V L-like domains. The binding domains comprise linked CDR and FR regions, which may be derived from separate immunoglobulins.      The proteins may also include other polypeptide sequences which function, e.g., as an enzyme, toxin, binding site, or site for attachment to an immobilization media or radioactive atom. Methods are disclosed for producing the proteins, for designing BABS having any specificity that can be elicited by in vivo generation of antibody, for producing analogs thereof, and for producing multifunctional synthetic proteins which are self-targeted by virtue of their binding site region.
Patent CA-1308857-C (CA)
Title: Propylene copolymerization process
Inventor: PELLON BRIAN J
IPC: C08F4/64
Filed: 1988-07-07
Granted: 1992-10-13
Abstract: NOVEL PROPYLENE COPOLYMERIZATION PROCESS                            ABSTRACT      A novel highly efficient process is disclosed for the produc-tion of substantially amorphous propylene-butene-1 copolymers. The polymers have properties which make them applicable for use, e.g., as blending components in hot melt adhesives and roofing material.
Patent CA-1328077-C (CA)
Title: Antipsychotic compositions containing dioxopiperidine  derivatives
Inventor: COSTALL BRENDA
IPC: A61K31/445
Filed: 1988-07-11
Granted: 1994-03-29
Abstract: ABSTRACT        ANTIPSYCHOTIC COMPOSITIONS CONTAINING                  DIOXOPIPERIDINE DERIVATIVES    Phenyl-3-aminoalkyl-4-methyl-2,6-dioxopiperidines of the Formula I                                                   (I) wherein:    R1 represents hydrogen or C1-C4 alkyl; n is 1 or 2;    R2 represents hydrogen or methyl, provided that one R2 is hydrogen when n is 2;    R3 represents hydrogen or C1-C2 alkyl;    R4 represents C1-C2 alkyl;    R5 and R6 independently represent hydrogen or methyl; m is 0 to 3; and each Y is in a meta or para position and independently represents hydroxy, C1-C2 alkoxy, C1-C2 alkyl, C1-C2 hydroxyalkyl, halogen, or trifluoromethyl, provided that hydroxy and alkoxy are not in the para position, and pharmacologically acceptable salts thereof have antiposychotic activity without sedative side effects.          They are particularly useful in the treatment of schizophrenia.  The presently preferred compound is 3-(3'methoxyphenyl)-3-(3"-N,N-dimethylaminopropyl) -4,4-dimethyl-2,6-dioxopiperidine (AGN 2979).
Patent CA-1298757-C (CA)
Title: Manifold
Inventor: DRAKE LAWRENCE V
IPC: F28F9/02
Filed: 1988-07-13
Granted: 1992-04-14
Abstract: ABSTRACT OF THE DISCLOSURE        A manifold which is useful in receiving a heated liquid such as warm water from a suitable source and for distributing that liquid to a plurality of floor heat exchangers and for receiving liquid from the heat exchangers and returning that liquid to the source.  The manifold includes a plurality of separate manifold elements that can be stacked adjacent one another, each element having a first and second chamber.  The first and second chambers of the elements together define first and second distribution vessels within the manifold.  Each manifold element includes inlet and outlet ports communicating with the respective distribution vessels for carrying liquid to and from the heat exchangers.  The manifold elements desirably are integrally formed from plastic or other material exhibiting a coefficient thermal conductivity of less than 1.0 kcal/M h °C.
Patent CA-1303197-C (CA)
Title: Electrically self-oscillating, rf-excited gas laser
Inventor: LAAKMANN PETER
IPC: H01S3/0975
Filed: 1988-08-15
Granted: 1992-06-09
Abstract: AN ELECTRICALLY SELF-OSCILLATING, RF-EXCITED GAS LASER                 Abstract of the Disclosure An  electrically  self-oscillating  radio  frequency-excited gas laser.   The discharge section of the laser reso-nates at a desired radio frequency as a result of incorporating the discharge section into the feedback loop of a power oscilla-tor circuit.   This laser structure facilitates initial plasma breakdown and adapts its frequency depending upon whether the gas in the discharge section has broken down.   When the laser plasma  tube is integrated with the oscillator,  the laser  is also somewhat smaller compared to gas  lasers having conven-tional crystal-controlled amplifier chains.
Patent CA-1309631-C (CA)
Inventor: AKKAS TAMER
IPC: A61B17/00
Filed: 1988-10-04
Granted: 1992-11-03
Abstract: SURGICAL CUTTING INSTRUMENT     Abstract of the Disclosure A surgical cutting instrument such as for use in intra-ocular surgery having a handpiece with an elongate probe extend-ing forward from it.  The probe has an elongate stationary outer cutter with a port at its tip and an elongate inner cutter with a cutting surface coaxially disposed therein. The interior of the inner cutter communicates with a vacuum source.  A spring and diaphragm assembly in the handpiece and powered by a low pressure pump causes the inner cutter to rapidly reciprocate axially in the outer cutter, and body material, such as vitreous material, drawn in through the port by the vacuum source is thereby chopped by the cutting surface and aspirated out of the patient's body through the handpiece.  A large adjustment nut on the handpiece allows the size of the port to be easily adjusted.  Irrigation fluid can be provided at the surgical site through an infusion cap which is adjustable both longitudinally and rotatably on the handpiece.