baber/WOPTO huggingface dataset:
Patent CA-2613345-A1 (CA)
Inventor: KOGA YOSHIHIKO
IPC: A61K35/74
Filed: 2006-06-29
Abstract: L'invention concerne une composition améliorant une activité diurne réduite et/ou les symptômes de la dépression, comprenant de l'acide arachidonique et/ou un composé ayant de l'acide arachidonique comme acide gras constitutif.
Patent CA-2613622-A1 (CA)
Title: Alert methods and apparatus for call appointments in a calendar application based on communication conditions of a mobile station
Inventor: WILLEY WILLIAM DANIEL
IPC: H04M1/72451
Filed: 2007-12-04
Abstract: Alert methods and apparatus for call appointments in a calendar application based on communication conditions of a mobile station are disclosed. Calendar information for an appointment in the calendar application is received and stored in memory.  The calendar information is associated with a date and time of the appointment. In response to identifying an out-of-coverage condition of the mobile communication device within a predetermined time period of the date and time of the appointment, a warning indication is produced at a user interface of the mobile communication device. The warning indication may be or include a message which instructs a user of the mobile communication device to relocate the mobile communication device for removing the out-of-coverage condition, and may also include an audible or vibrating alert. The warning indication may be provided only if a telephone number or other suitable call information is identified within the calendar information.
Patent CA-2614468-A1 (CA)
Inventor: SHALOM-KLEIN SAGIT
IPC: A61K31/542
Filed: 2005-07-15
Abstract: One of the objects of the invention relates to a pharmaceutical composition in the form of a granulate, wherein the granulates comprises an active pharmaceutical ingredient (API) having a poor water solubility intimately associated with at least one pharmaceutically acceptable sugar, and optionally or preferably at least one pharmaceutically acceptable excipient other than the at least one pharmaceutically acceptable sugar, wherein the active pharmaceutically ingredient has a water solubility less than about 20 mg/ml.  The at least one pharmaceutically acceptable excipient other than the at least one pharmaceutically acceptable sugar is selected from the group consisting of disintegrants, wetting agents, diluents, binders, lubricants, glidants, coloring agents and flavoring agents. The at least one pharmaceutically acceptable sugar is preferably selected from pyranosyl pyranoses, such as lactose. Another object of the invention relates to a process for preparing a pharmaceutical granulate, comprising (a) combining an API having poor water solubility with a solution comprising at least one pharmaceutically acceptable sugar, for example a pyranosyl pyranose such as lactose, and a solvent, and optionally at least one pharmaceutically acceptable excipient other than the at least one pharmaceutically acceptable sugar to form a combined mixture; (b) drying the combined mixture of step (a); and (c) comminuting the product of step (b) to obtain the granulate.
Patent CA-2614526-A1 (CA)
Title: Benzimidazole formulation
Inventor: BERTELSEN POUL
IPC: A61K31/4439
Filed: 2006-07-11
Abstract: A dry manufacturing process for the production of a pharmaceutical formulation of a benzimidazole and an alkaline substance is described. A tablet is compressed directly from a dry powder or a dry particulate matter avoiding any liquid or excipient conventionally used as a wet binder. The manufacturing process has the advantage of being simple and cost efficient. At the same time an expensive drying step is superfluous. The resulting pharmaceutical formulation has a good stability and a good dissolution profile.
Patent CA-2615238-A1 (CA)
Title: Preparation of terazole derivatives
Inventor: SEDELMEIER GOTTFRIED
IPC: C07D403/04
Filed: 2006-07-17
Abstract: The invention relates to a process for the preparation of (S)-pyrrolidine-1H-tetrazole derivatives of formula (I), wherein R1, R2 and R3, independently of one another, represent hydrogen, halogen or an organic radical, in racemic form or as an enantiomer, a tautomer, an analog thereof or a salt thereof.
Patent CA-2616053-A1 (CA)
Inventor: LILGE DIETER
IPC: C08F4/70
Filed: 2006-07-13
Abstract: Method of preparing olefin polymers, which comprises the polymerization of at least one .alpha.-olefin in the presence of a hybrid catalyst to produce a polymer comprising at least a higher molecular weight polymer component and a lower molecular weight polymer component in the presence of water in an amount of from 2 to 100 mol ppm and/or carbon dioxide in an amount of from 2 to 100 mol ppm, in each case based on the total reaction mixture, in order to alter the ratio of the higher molecular weight polymer component to the lower molecular weight polymer component. This enables the ratio of the higher molecular weight component to the lower molecular weight component to be controlled selectively.
Patent CA-2619329-A1 (CA)
Inventor: GARROOD STUART
IPC: H04M1/72427
Filed: 2007-05-15
Abstract: A media engine for creating a graphical interface for an application on a device is disclosed. The media engine comprises an interaction interface for notifying the media engine of changes to the application, a renderer for rendering the graphical interface, a parser for parsing, from a template file, template information for controlling how the renderer renders the graphical interface, and a layout manager for optionally controlling the display of template information.
Patent CA-2620667-A1 (CA)
Title: Procedes et compositions pour vaccination d'animaux avec des antigenes prrsv presentant une immunogenicite amelioree
Inventor: OSORIO FERNANDO A
IPC: A61K39/00
Filed: 2006-08-30
Abstract: Des porcs chez qui on a introduit des variants hypoglycosylés de la principale protéine de surface GP5 du virus du syndrome dysgénésique et respiratoire du porc (PRRSV) ont révélé une production plus importante d'anticorps neutralisant le PRRSV par rapport aux niveaux d'anticorps neutralisants produits par des porcs immunisés avec une protéine GP5 glycosylée ou de type sauvage. Cette invention concerne des méthodes permettant d'obtenir des meilleures réponses immunitaires au PRRSV chez des porcs. Cette invention concerne également des compositions utiles pour obtenir les réponses immunitaires améliorées, ainsi que des polynucléotides isolés codant pour des variants hypoglycosylés de la principale protéine de surface GP5 du PRRSV.
Patent CA-2621982-A1 (CA)
Inventor: KIRN DAVID
IPC: A61K39/00
Filed: 2006-09-07
Abstract: The present invention concerns methods and compositions for the treatment of cancer and cancer cells using intravascular administration of a vaccinia virus. In some embodiments, methods and compositions involve a replicative vaccinia virus that encodes GM-CSF.
Patent CA-2622954-A1 (CA)
Title: Complexe de renforcement mecanique destine a etre incorpore dans une piece composite, et procede de fabrication d'une telle piece
Inventor: SANIAL PHILIPPE
IPC: D04H3/12
Filed: 2006-09-28
Abstract: Complexe de renforcement mécanique (3), destiné à être incorporé dans une pièce composite (1) avec noyau injectée (2) à base de résine, comportant une structure textile de renfort (5), destinée à être imprégnée d'une résine mécanisante thermodurcissable. Il se caractérise en ce qu'il comporte une couche de mousse (4) à cellules ouvertes, présente sur la face interne du complexe (3), destinée à venir au contact du noyau injecté (2).
Patent CA-2623125-A1 (CA)
Title: Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors
Inventor: HALEY JOHN D
IPC: G01N33/574
Filed: 2006-09-19
Abstract: The present invention provides diagnostic and prognostic methods for predicting the effectiveness of treatment of a cancer patient with an IGF-1R kinase inhibitor. Methods are provided for predicting the sensitivity of tumor cell growth to inhibition by an IGF-IR kinase inhibitor, comprising assessing whether the tumor cell has undergone an epithelial to mesenchymal transition (EMT), by determining the expression level of epithelial and/or mesenchymal biomarkers, wherein tumor cells that have undergone an EMT are substantially less sensitive to inhibition by IGF-IR kinase inhibitors. Improved methods for treating cancer patients with IGF-1R kinase inhibitors that incorporate the above methodology are also provided. Additionally, methods are provided for the identification of new biomarkers that are predictive of responsiveness of tumors to IGF-1R kinase inhibitors. Furthermore, methods for the identification of agents that restore the sensitivity of tumor cells that have undergone EMT to inhibition by IGF-1R kinase inhibitors are also provided.
Patent CA-2624744-A1 (CA)
Title: Filling system for potentially hazardous materials
Inventor: TARTAGLIA DANIEL
IPC: G21F5/06
Filed: 2007-10-26
Abstract: Systems, devices, and methods for filling containers with radioactive materials are described. In certain embodiments, the systems comprise a shielding material that substantially defines a chamber and, preferably, substantially blocks radioactivity, a conduit extending through the shielding material into the chamber, and a securing unit that is disposed in the chamber proximal to the conduit and is adapted to receive a container through the conduit.
Patent CA-2624788-A1 (CA)
Inventor: MALLADI RAMANA
IPC: A61K31/568
Filed: 2006-10-12
Abstract: The present invention relates to an improved transdermal hydroalcoholic testosterone gel formulation that provides, among other things, a desirable pharmacokinetic hormone profile, and methods of use.
Patent CA-2624930-A1 (CA)
Inventor: TAM SANG WILLIAM
IPC: A01N43/58
Filed: 2006-10-04
Abstract: The invention provides methods for (a) reducing mortality associated with heart failure; (b) improving oxygen consumption; (c) treating heart failure;  (d) treating hypertension; (e) improving the quality of life in a heart failure patient; (f) inhibiting left ventricular remodeling; (g) reducing hospitalizations related to heart failure; (h) improving exercise tolerance;  (j) increasing left ventricular ejection fraction; (k) decreasing levels of B-type natriuretic protein; (1) treating renovascular diseases; (m) treating end-stage renal diseases; (n) reducing cardiomegaly; (o) treating diseases resulting from oxidative stress; (p) treating endothelial dysfunctions; (q) treating diseases caused by endothelial dysfunctions; or (r) treating cardiovascular diseases; in a patient in need thereof, wherein the patient has a Arg389Arg polymorphism and/or a Gly389Gly polymorphism in the beta 1 adrenergic receptor gene, compiising administering to the patient (i) at least one antioxidant compound or a pharmaceutically acceptable salt thereof; (ii) at least one nitric oxide enhancing compound; and (iii) optionally the best current therapy for the treatment of cardiovascular diseases. In one embodiment the antioxidant is a hydralazine compound or a pharmaceutically acceptable salt thereof and the nitric oxide enhancing compound is isosorbide dinitrate and/or isosorbide mononitrate.
Patent CA-2625107-A1 (CA)
Title: A seating system and a passenger accomodation unit for a vehicle
Inventor: DOY GARY
IPC: B60N2/34
Filed: 2002-08-09
Abstract: A passenger seat assembly for a vehicle, particularly an aircraft, which is adapted to provide self-contained, individual seating and sleeping accommodation for a passenger, said seat assembly comprising: supporting structure (42) for supporting said assembly off the floor of a vehicle; one or more movable passenger-bearing, structural components (71, 72); and means for connecting said movable, structural components to said structure such that said components can be selectively moved between a seat configuration, in which a plurality of passenger-bearing surfaces on said one or more structural, movable components (71, 71) or said supporting structure form a seat for the passenger, and a bed configuration, in which a plurality of said bearing surfaces (47,48, 67, 74, 76) are disposed substantially coplanarly and substantially contiguously to form a bed for the passenger.
Patent CA-2625635-A1 (CA)
Inventor: MALMBERG KARL GUNNAR
IPC: H05K7/20
Filed: 2005-11-11
Abstract: In a method for cooling an electronic application (1; 101) having at least one heat-generating electronic component (3) mounted on a circuit board (2), a heat sink (6) is attached to the circuit board in heat transferring thermal contact (6T, 3T) with one heat generating electronic component (3) by first being statically fixed to the circuit board in a stationary position at a specified height (L) above said circuit board and by then being resiliently biasing the component against the heat sink.
Patent CA-2625908-A1 (CA)
Inventor: VAURES FREDERIC
IPC: C09D103/04
Filed: 2006-10-26
Abstract: La présente invention a trait au domaine pharmaceutique, cosmétique, nutraceutique et alimentaire et plus particulièrement à celui des compositions prêtes à l~emploi destinées à l~enrobage des comprimés, gélules, capsules et autres formes solides ou semi solides couramment utilisées dans ces différents domaines d~applications. L~invention concerne plus particulièrement des compositions solides prêtes à l~emploi destinées à la réalisation de solutions ou dispersions de pelliculage pour formes solides ou semi solides, remarquables en ce que la viscosité de ces solutions ou dispersions après reconstitution à froid, est inférieure à 1000 Centipoises, pour une concentration en matières solides supérieure à 20%, cette viscosité étant obtenue par l~utilisation d~agents filmogènes d~origine naturelle, solubles à  froid et de faible viscosité en milieu aqueux pour de hautes concentrations.
Patent CA-2626930-A1 (CA)
Inventor: PISOT PHILIPPE
IPC: F16K1/30
Filed: 2006-10-18
Abstract: The invention relates to an element for controlling filling and/or drawing of a pressurized gas, to be mounted in an opening of a tank (1), comprising a body (21) provided with at least one device (8) for controlling the circulation of gas placed between a first end, which has an opening (31) forming an inlet and/or an outlet for the gas with regard to the tank, and a second end for communicating with the inside of the tank. The control element also comprises a safety gas escape device (5) for evacuating the gas from the reservoir in the event of a dangerous situation and comprises a channel or gas escape circuit (215, 213, 212, 211, 31) running between a first end (215) for communicating with the pressurized gas of the tank and a second end (31) for communicating with a user circuit or with the atmosphere, the escape circuit being closed or not according to the state of a safety element (52), characterized in that the second end of the gas escape circuit (215, 213, 212, 211, 31) coincides with the opening (31) of the control element forming an inlet and/or an outlet for the gas.
Patent CA-2630452-A1 (CA)
Inventor: ARMSTRONG DAVID
IPC: A61B17/00
Filed: 2006-12-01
Abstract: A method of occluding a defect in a patient is provided. The method includes inserting a placement member, such as a wire guide, into a defect; advancing the placement member to a desired location; inserting the placement member into a lumen in an occluding member, such as a plug or a graft; and advancing the occluding member to the desired location by inserting the placement member into a lumen in a pusher member and pushing the occluding member with the pusher member until the occluding member reaches the desired location. Medical devices and systems for occluding defects are also provided.
Patent CA-2637342-A1 (CA)
Title: Protective cover
Inventor: SLATER OWEN
IPC: A47B13/08
Filed: 2006-11-17
Abstract: A cargo protector disclosed herein provides a flexible panel having at least one channel located on the flexible panel to hold a tensile strip, wherein the tensile strip is adapted to be folded into at least three loops in such a manner. The arrangement of the tensile strip inside the flexible panel as disclosed herein allows the cargo protector to be conveniently packed away into a compact storage form or to be quickly and easily deployed for a number of different uses.
Patent CA-2637799-A1 (CA)
Title: Method for obtaining fuels from vegetable and animal fat waste and installation for carrying out said method
Inventor: FARWICK STEFAN
IPC: C10L1/02
Filed: 2006-10-02
Abstract: The invention relates to a method for obtaining fuels from vegetal and/or animal fat waste which contain, in addition to fat and/or oils, free fatty acids. The free fatty acids contained in the fat waste are reacted at reaction temperatures of above 220 ~C with at least one polyvalent alcohol in the absence of enzymatic and solid neutral catalysts so as to produce the esterification of the free fatty acids.
Patent CA-2638961-A1 (CA)
Inventor: DOOLEY KEVIN
IPC: H02J3/02
Filed: 2008-08-20
Abstract: An aircraft electrical system includes a generator that supplies electrical AC    power to a plurality of accessories associated with a gas turbine engine. The generator also supplies power to an aircraft DC bus in parallel to the supply to the accessory bus.
Patent CA-2640813-A1 (CA)
Title: Promotional coupon system with anonymous player tracking in a gaming environment
Inventor: MEYERHOFER ERIC
IPC: A63F9/24
Filed: 2007-01-30
Abstract: Methods and apparatuses for a promotional coupon system which can provide promotions and promotional coupons to all patrons of a casino, specifically to patrons who do not want to provide personal information yet would enjoy receiving promotions. Casinos can track an anonymous player and offer incentives such as promotional coupons to the player to entice them to return to the casino. The system provides a means for the creation and issuance of promotional coupons as well as the tracking of the redemption of such coupons and the tracking of anonymous players, to provide real-time monitoring of a gaming printer's activities; for connecting to other existing systems in a casino, such as an accounting system or point-of-sale system. Additionally, such a system may use existing equipment such as a gaming printer to produce such coupons, however, only after the existing equipment produces a cash-out voucher.
Patent CA-2644128-A1 (CA)
Title: Method and apparatus for synchronizing base stations
Inventor: DICK STEPHEN G
IPC: H04W92/00
Filed: 2003-02-04
Abstract: Method and apparatus for synchronizing base stations employing an independent synchronizing source or identifying a base station as a master source. An RNC (C-RNC) or a base station may designate one base station or a UE to acquire measurements derived from base stations to achieve synchronization. Synchronization activities may be regularly scheduled or may be undertaken when periodic measurements indicate that a drift value exceeds a given threshold.
Patent CA-2645859-A1 (CA)
Title: 2'-fluoronucleoside phosphonates as antiviral agents
Inventor: SHI JUNXING
IPC: A61P31/18
Filed: 2007-03-23
Abstract: The present invention includes compounds and compositions of ®-2'- fluoronucleoside phosphonates, as well as methods to treat HIV, HBV1 HCV or abnormal cellular proliferation comprising administering said compounds or compositions. These compounds are represented by the formulas (I), (II), (III), (IV).
Patent CA-2646687-A1 (CA)
Inventor: SPRONCK JULIEN FELIX PAUL
IPC: G01B9/02
Filed: 2007-03-26
Abstract: The invention relates to an optical system for providing on-axis destructive interference of light received from an object along a predetermined system optical axis. The system comprises a receiving and guiding optical structure and a combining optical structure. The receiving and guiding optical structure is for receiving and guiding at least three beams of light received from said object, the receiving and guiding optical structure arranged to provide a relative optical path difference between the at least three beams; the combining optical structure is for combining the at least three beams. According to the invention, a polarization varying optical structure is arranged between the receiving and guiding optical structure and the combining optical structure, for varying a polarization state of the beams relative to each other in order to provide on-axis destructive interference.
Patent CA-2648481-A1 (CA)
Inventor: FINLAISON DEBORAH SUSAN
IPC: C12N15/40
Filed: 2007-04-20
Abstract: The application relates to a pestivirus, designated PMC virus, that is associated with porcine myocarditis syndrome, and the gene and protein sequences derived therefrom. The application further relates to detection methods, vaccine therapeutics, and diagnostic methods using the PMC virus or gene/protein sequences derived therefrom.
Patent CA-2656264-A1 (CA)
Inventor: KITAMURA MITSUTAKA
IPC: A61P19/06
Filed: 2007-06-22
Abstract: A process for selective production of crystal A of 2- (3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid which comprises dissolving 2-(3-cyano-4-isobutyloxy- phenyl)-4-methyl-5-thiazolecarboxylic acid in methanol or a methanol/water mixed solvent (having a methanol/water volume ratio of 90/10 or above), adding water to the resulting solution to adjust the methanol/water ratio to 7/3, and adding a specified amount of seed crystals to the solution during the addition of water at a specified stage.
Patent CA-2656517-A1 (CA)
Inventor: ROUSSEL CLAUDE
IPC: H01M8/02
Filed: 2007-06-19
Abstract: The present invention relates to the use of the A286 alloy grade for the manufacture of a sheet, optionally surfaced, making it possible to obtain a conducting plate of mono polar or bipolar type for a fuel cell element. The invention also relates to this optional surface treatment process, which comprises a cold-rolling step followed by a continuous annealing step in an oxidizing atmosphere and by an acid pickling step.
Patent CA-2656575-A1 (CA)
Title: Synthetic resin bottle
Inventor: SASAKI MASAAKI
IPC: B65D1/02
Filed: 2007-06-05
Abstract: A synthetic resin bottle whose plastic deformation under buckling is limi ted to provide the bottle with high commercial value. The PET bottle (100) h as a body section (130) continuing to a mouth section (110) via a shoulder s ection (120) and also has a constricted section (150) lying around the body section (130) in its circumferential direction. The body section (130) has a front wall section (130a) and rear wall section (130b) facing each other, a left wall section (130c) and right wall section (130d) facing each other, a nd connection sections (130e) for connecting the wall sections (130a-130d) t o each other. The outer shape of a cross section of the body section (130) t aken along the circumferential direction is substantially a polygon. The con stricted section (150) has left lateral grooves (1a, 2a) extending in the ci rcumferential direction from a left wall section (150c) up to at least conne ction sections (150e) and also has right lateral grooves (1b, 2b) extending in the circumferential direction from a right wall section (150d) up to at l east connection sections (150e). Ends (1ae, 1be, 2ae, 2be) at which the late ral grooves (1a, 1b, 2a, 2b) are close to each other are separated from each other to form intermittent sections.
Patent CA-2656887-A1 (CA)
Title: Antitumor combinations containing taxane derivatives
Inventor: VRIGNAUD PATRICIA
IPC: A61K39/395
Filed: 2007-07-31
Abstract: A pharmaceutical composition comprised of acetocyclopropyl taxotere or a derivative thereof, and at least one of an alkylating agent, an antimetabolite, a spindle poison, an epidophyllotoxin, an antibiotic, an enzyme, a topoisomerase inhibitor, a platinum coordination complex, a biological response modifier or a growth factor inhibitor is described.
Patent CA-2656923-A1 (CA)
Inventor: HYMOWITZ SARA
IPC: G01N23/20
Filed: 2007-06-19
Abstract: The present disclosure provides crystals of and structural coordinates of mOX40L, hOX40L, hOX40 receptor and complexes thereof. The crystals and crystal structures are useful, for example, in the design and synthesis of modulators of mOX40L, hOX40L, and/or hOX40 receptor.