baber/WOPTO huggingface dataset:
Patent AU-2019324162-A1 (AU)
Title: Immunotherapy targeting KRAS or Her2 antigens
Inventor: VEATCH JOSHUA
IPC: A61K39/00
Filed: 2019-08-21
Abstract: Binding proteins and high affinity recombinant T cell receptors (TCRs) specific for KRAS G12V or Her2-ITD neoantigens are provided herein. Compositions and recombinant host cells encoding and/or expressing the binding proteins and/or high affinity recombinant TCRs are also provided. The compositions and recombinant host cells may be used to treat a subject having non-small cell lung cancer (NSCLC), colorectal cancer, pancreas cancer, ovarian cancer, breast cancer, biliary tract cancer, an indication wherein a KRAS G12V neoantigen is a therapeutic target, or an indication wherein a Her2-ITD neoantigen is a therapeutic target. Related vaccines, vaccine therapies, and vaccination regimens are also provided.
Patent AU-2019346388-A1 (AU)
Title: Pesticidal combinations of Yersinia and insect viruses
Inventor: LELAND JARROD
IPC: A01P7/04
Filed: 2019-09-23
Abstract: Disclosed herein are pesticicial combinations, including combinations of
Patent AU-2019393145-A1 (AU)
Title: Trench shoring apparatus and its method of use
Inventor: MOLYNEUX GLENN
IPC: E02D17/08
Filed: 2019-11-29
Abstract: The present invention relates to a trench shoring apparatus, comprising: first and second side panels connected in a parallel spaced-apart configuration by a connecting rod pivotally connected to one end of one or more pairs of lateral arms, the other opposite end of the one or more pairs of lateral arms being hingedly connected to the side panels, such that translational movement of the connecting rod in a direction parallel to the side panels causes the spaced-apart panels to move between retracted and extended parallel spaced-apart configurations.
Patent AU-2019393853-A1 (AU)
Title: Decorative panel, and decorative floor covering consisting of said panels
Inventor: BOUCKÉ EDDY ALBERIC
IPC: C08K5/12
Filed: 2019-09-30
Abstract: In the field of decorative floor coverings, decorative panels are known having a MDF (Medium Density Board) or HDF (High Density Board) based core layer on top of which a decorative substrate is attached to provide the panels a desired appearance. The invention relates to a panel, in particular a decorative panel, a floor panel, a ceiling panel or a wall panel. The invention also relates to a floor covering consisting of a plurality of mutually coupled panels.
Patent AU-2019401796-A1 (AU)
Title: System for preparing a beverage from a capsule using a fluid supplied under pressure into the capsule and a capsule for use in such a system
Inventor: KAMERBEEK RALF
IPC: A47J31/36
Filed: 2019-12-18
Abstract: System for preparing a potable beverage, including a capsule, a first beverage preparation device and a second beverage preparation device, each arranged for receiving the capsule. The capsule including a sealing member at the outwardly extending flange for providing a fluid sealing contact with the first enclosing member if the capsule is used in the first beverage preparation device. There is a first sealing interface between the capsule and the first enclosing member for providing a fluid sealing contact if the capsule is positioned in the first enclosing member and the first enclosing member is closed by means of the first closing member, and there is a second sealing interface between the capsule and the second enclosing member for providing a fluid sealing contact if the capsule is positioned in the second enclosing member and the second enclosing member is closed by means of the second closing member, the second sealing interface being different than the first sealing interface.
Patent AU-2019431082-A1 (AU)
Title: Composition, for preventing, relieving or treating cartilage-related diseases or symptoms, comprising HAPLN1
Inventor: KIM DAE KYONG
IPC: A61K31/728
Filed: 2019-02-28
Abstract: The present invention relates to a composition, for preventing, relieving or treating cartilage-related diseases or symptoms, comprising hyaluronan and proteoglycan link protein 1 (HAPLN1) as an active ingredient. Specifically, the present invention provides a composition for regenerating cartilage, a composition for preventing, relieving or treating osteoarthritis or a composition for regenerating growth plate cartilage, which comprise HAPLN1 as an active ingredient.
Patent WO-2021077175-A1 (WO)
Title: Adoptive immunotherapy
Inventor: KHANNA RAJIV
IPC: A61K39/245
Filed: 2020-10-23
Abstract: Disclosed herein is the use of a first population of allogeneic T-cells recognizing a first EBV epitope, and a second allogeneic population recognizing a second EBV epitope in the treatment of EBV-associated disorders. Also dislosed is the use of a population of allogeneic T-cells recognizing an EBV antigen in combination with a further therapeutic agent such as an immunotherapeutic agent, a MAPK, BET or MEK. pathway inhibitor for treating EBV-associated disease.
Patent AU-2020200874-A1 (AU)
Title: Long-acting polypeptides and methods of producing and administering same
Inventor: FARES FUAD
IPC: A61K38/27
Filed: 2020-02-06
Abstract: CTP-modified human growth hormone polypeptides and pharmaceutical formulations and pharmaceutical compositions comprising the same and methods of producing, and using the same are disclosed.
Patent AU-2020201064-A1 (AU)
Title: System and method for performance optimization in and through a distributed antenna system
Inventor: STAPLETON SHAWN PATRICK
IPC: H04B10/00
Filed: 2020-02-14
Abstract: Abstract A method for operating a DAS includes providing a set of digital remote units (remotes) operable to send and receive wireless radio signals. Each of the set of remotes is associated with a geographic area. The method also includes providing a digital access unit (host) operable to communicate with the set of remotes, receiving uplink signals at one or more of the set of remotes, and monitoring train activity in the geographic areas. The method further includes increasing a gain coefficient associated with one of the set of remotes in response to determining an increase in monitored train activity, decreasing a gain coefficient associated with another of the set of remotes in response to determining a decrease in monitored train activity, and transmitting, to the host, scaled uplink signals associated with the one of the set of remotes and the another of the set of remotes.
Patent AU-2020201117-A1 (AU)
Title: Processes and systems for preparing nucleic acid sequencing libraries and libraries prepared using same
Inventor: HARDENBOL PAUL
IPC: B01J19/00
Filed: 2020-02-17
Abstract: This disclosure provides methods for preparing a sequencing library including the steps of providing a template nucleic acid sequence, dNTPs, dUTP, a primer, a polymerase, a dUTP excising enzyme, and a plurality of beads including oligonucleotide adapter sequence segments; amplifying the template nucleic acid with the polymerase, dNTPs, dUTP and random hexamer to provide a complementary nucleic acid sequence including occasional dUTPs; and excising the incorporated dUTPs with the dUTP excising enzyme to provide nicks in the complementary nucleic acid sequence to provide a sequencing library. l) Fig.I
Patent AU-2020202968-A1 (AU)
Title: Method of treating conditions of the eye with an anti-VEGF darpin
Inventor: HOHMAN THOMAS
IPC: A61K38/17
Filed: 2020-05-05
Abstract: METHOD OF TREATING CONDITIONS OF THE EYE WITH AN ANTI-VEGF DARPIN 5 Disclosed herein are methods for the treatment of a patient having an exudative age-related macular degeneration and other conditions of the retina by administering a binding protein comprising an ankyrin repeat domain, wherein the binding protein is first administered in 2 to 5 doses, with an interval of 25 to 35 days between each dose, and then is administered in additional doses with a longer interval between doses.
Patent AU-2020204117-A1 (AU)
Title: Hybrid cooler with bifurcated evaporative section
Inventor: BUGLER THOMAS W
IPC: F28F25/08
Filed: 2020-06-19
Abstract: A hybrid closed circuit heat exchanger having a dry indirect section and an evaporative indirect 
section. The evaporative indirect section has multiple sub-sections. An evaporative fluid distribution 
system is configured to selectively distribute evaporative fluid over all, part, or none of the sub
sections. A process fluid flow path control system is configured to selectively direct the process fluid 
through one or more sub-sections. The process fluid flow path control system may send all of the 
process fluid through two or more sub-sections in equal amounts or in different amounts. There is 
preferably no evaporative heat exchange section bypass flow path.
Patent AU-2020207211-A1 (AU)
Title: De novo design of protein switches for tunable control of protein degradation
Inventor: LANGAN ROBERT
IPC: C07K14/00
Filed: 2020-01-06
Abstract: Disclosed herein are non-naturally occurring cage polypeptides, kits and degron LOCKRs including the cage polypeptides, and uses thereof, wherein the cage polypeptides include (a) a helical bundle, comprising between 2 and 7 alpha-helices, wherein the helical bundle includes: (i) a structural region; and (ii) a latch region, wherein the latch region composes a degron located within the latch region, wherein the structural region interacts with the latch region to prevent activity of the degron; and (b) amino acid linkers connecting each alpha helix
Patent AU-2020220841-A1 (AU)
Title: Refrigerator having wiring mechanism
Inventor: WEI DONG
IPC: F25D23/00
Filed: 2020-01-15
Abstract: Disclosed is a refrigerator (100) having a wiring mechanism (40). The refrigerator comprises a refrigerator body (10) and a drawer-type door body (20), wherein the refrigerator body (10) forms a compartment (11) provided with an opening facing forward, and the drawer-type door body (20) is provided with an electrical component. The wiring mechanism (40) comprises a cable (44) for supplying power to the electrical component, and a drag chain (45) for accommodating part of the cable, wherein one end of the drag chain (45) is fixed inside the compartment (11), and the other end of the drag chain (45) is connected to the drawer-type door body (20) and moves forward and backward along with the drawer-type door body (20), thereby preventing the drag chain (45) from being deformed and damaged, and ensuring a reliable electrical connection.
Patent AU-2020221059-A1 (AU)
Title: Gap configuration for multiple transport blocks
Inventor: LIU LE
IPC: H04L5/00
Filed: 2020-02-10
Abstract: Some techniques and apparatuses described herein provide for the determination of a gap for a scheduled communication involving multiple, different TBs. For example, some techniques and apparatuses described herein provide for the determination of a gap between two or more PDSCHs that are scheduled by a same DCI based at least in part on a UE capability, such as a processing time or a processing mode. Some techniques and apparatuses described herein provide for the determination of a gap between a last PDSCH and a next PDCCH based at least in part on the UE capability. The gap(s) may permit the UE to successfully receive and/or decode multiple PDSCHs and/or PDCCHs in view of the limitations imposed by the UEs processing time or processing mode. In this way, efficiency of PDSCH/PDCCH resource utilization may be improved, the likelihood of a failed PDCCH transmission is reduced, and network efficiency is improved.
Patent AU-2020259997-A1 (AU)
Title: Compounds and methods for the treatment of ocular disorders
Inventor: HOLMES IAN
IPC: A61P27/02
Filed: 2020-04-16
Abstract: Described herein are compositions and methods for the treatment of ocular surface disorders including meibomian gland dysfunction, blepharitis, dry eye disease and other inflammatory/ infections disease of the anterior surface of the eye. Said compositions and methods comprise keratolytic conjugate which demonstrate keratolytic activity, and anti-inflammatory or other desirable activities. Topical administration of said compositions to the eye, ocular surface or surrounding areas provides therapeutic benefit to patients suffering from ocular surface disorders.
Patent AU-2020273988-A1 (AU)
Title: Drop cart with cashbox data reader array and autonomous drop cart processing system for automated casino accounting
Inventor: PECHINKO PAUL
IPC: G06Q50/34
Filed: 2020-05-07
Abstract: An autonomous drop cart processing system is described. The system is configured to communicably couple with a drop cart that includes an array of cashbox data readers configured to interface with cashbox data transmitters associated with cashboxes inserted into compartments of the drop cart. As a result of this construction, the autonomous drop cart processing system can remove contents of each cashbox on the drop cart without needing to remove the cashbox from the drop cart in order to read the data from the cashbox data transmitter.
Patent AU-2020275407-A1 (AU)
Title: Coating compositions and systems and methods of applying such coating compositions
Inventor: REIL SVEN
IPC: C09D11/30
Filed: 2020-05-12
Abstract: A coating composition for precision application includes: a coating composition including a film-forming resin dispersed in an aqueous medium; a crosslinker reactive with the film-forming resin; a rheology modifier; a colorant; and a swelling solvent that swells the film-forming resin. The solids content of the coating composition is less than 25 weight %, based on the total weight of the coating composition. A system and method for precision application of a coating composition over at least a portion of a substrate are also disclosed. A substrate coated with a multi-layer coating system is also disclosed.
Patent AU-2020301307-A1 (AU)
Title: Double thermoform cannula
Inventor: TAO ZENGHONG
IPC: A61M60/13
Filed: 2020-06-25
Abstract: Systems and methods for providing a reinforced cannula for use in a blood pump assembly. The reinforced cannula comprises one or more thermoformed reinforced end portions. The thermoformed reinforced end portions may be stiffer than a medial portion of the cannula, allowing the medial portion of the cannula body to stretch and bend more readily than the cannula ends when the cannula is subject to an applied stress, reducing the stress and strain on the cannula ends.
Patent AU-2020312856-A1 (AU)
Title: Radiopaque polymers
Inventor: BRITTON HUGH
IPC: C08F8/44
Filed: 2020-07-20
Abstract: The present disclosure relates to radiopaque PVA polymers where the PVA has a first pendant group and a second pendant group, wherein the first pendant group comprises a first phenyl group bearing 1 to 5 iodine atoms, and the second pendant group comprises either (a) a second phenyl group bearing 1 to 3 substituents selected from the group W and optionally 1 to 4 iodine substituents, the group(s) W and the optional iodines being the sole substituents of the second phenyl group. Each W is selected from –OH, -COOH, -SO
Patent AU-2020314975-A1 (AU)
Title: System and method for the transfer of content between devices
Inventor: ELCOCK ALBERT F
IPC: H04N21/436
Filed: 2020-07-20
Abstract: An exemplary method and computing device for receiving a user input and determining whether the user input is a casting action for outputting content from the client device to one or more target devices. The computing device at least one target device of the one or more target devices that is eligible to output the content and identifies content source information associated with the content to be output by the at least one identified target device. One or more content output instructions are generated for outputting the content to the at least one identified target device. The computing device sends the one or more content output instructions to the at least one identified target device over a wireless connection.
Patent AU-2020347662-A1 (AU)
Title: Solid food and solid milk
Inventor: HANYU KEIGO
IPC: A23C9/18
Filed: 2020-09-03
Abstract: Provided are a solid food that enables the manufacture of a product, said product being prevented from damage due to dropping and thus having improved transportation stability, and a solid milk. The solid food, which is obtained by solidifying a powder by compression molding, is provided with a main body 10 having a first surface 10A and a second surface 10B that is positioned back to back to the first surface 10A. In the main body 10, at least one hole 11, which penetrates through the main body 10 from the first surface 10A to the second surface 10B, is formed. The main body 10 is configured in such a manner that the first surface 10A, the second surface 10B and the inner wall surface 11A of the hole 11 constitute an outer surface which is harder than the inside of the main body 10.
Patent AU-2020356262-A1 (AU)
Title: Radiolabelled GRPR-antagonist for use as theragnostic
Inventor: MARIANI MAURIZIO F
IPC: A61K103/30
Filed: 2020-09-23
Abstract: The present disclosure relates to gastrin-releasing peptide receptor (GRPR) targeting pharmaceuticals and their use in a theragnostic approach for selection and therapy of subjects with GRPR-expressing malignancies. In particular, the present disclosure relates to a pharmaceutical composition of a radiolabeled GRPR-antagonist, for use in treating GRPR-positive tumors in a human subject selected for said treatment, wherein said subject has been selected for the treatment by PET/CT or PET/MRI imaging with a corresponding
Patent AU-2020371664-A1 (AU)
Title: Rapidly insertable central catheters and methods thereof
Inventor: HOWELL GLADE HAROLD
IPC: A61M25/00
Filed: 2020-10-22
Abstract: Rapidly insertable central catheters ("RICC") and methods thereof are disclosed. In an example, a RICC includes a catheter tube, a suture wing disposed over a medial portion of the catheter tube, a hub coupled to a proximal-end portion of the catheter tube, and a number of extension legs extending from the hub. The catheter tube can include a first section in a distal portion of the catheter tube formed of a first polymeric material having a first durometer. The catheter tube can also include a second section proximal of the first section of the catheter tube formed of a second polymeric material having a second durometer less than the first durometer. The catheter tube can have a column strength sufficient to prevent buckling of the catheter tube when inserted into an insertion site and advanced through a vasculature of a patient without use of the Seldinger technique.
Patent AU-2020437452-A1 (AU)
Title: Apparatus and method for establishing and maintaining DS-lite tunnel
Inventor: LI JU
IPC: H04L61/5014
Filed: 2020-03-27
Abstract: An electronic apparatus for establishing a Dual-Stack Lite (DS-lite) tunnel is provided. The apparatus sends a request for an Internet Protocol (IP) address of a Domain Name System (DNS) server and a domain name of an Address Family Transition Router (AFTR) server to a Dynamic Host Configuration Protocol (DHCP) server using an IP address of the DHCP server, receives the IP address of the DNS server and the domain name of the AFTR server from the DHCP server in response to the request, sends a DNS query including the domain name of the AFTR server to the DNS server using the IP address of the DNS server. In response to the DNS query being successful, the apparatus receives an IP address of the AFTR server from the DNS server, and establishes the DS-lite tunnel between the apparatus and the AFTR server using the IP address of the AFTR server.
Patent AU-2021203650-A1 (AU)
Title: Chemical compounds
Inventor: CATALANO JOHN G
IPC: C07D471/14
Filed: 2021-06-04
Abstract: DCC-3/06/2021 
ABSTRACT 
Compounds of Formula (I), specifically hepatitis B virus and/or hepatitis D virus 
inhibitors, more specifically compounds that inhibit HBe antigen and HBs antigen in a 
5 subject, for the treatment of viral infections, and methods of preparing and using such 
compounds.  
R2 R1 R11 0 
R3- R10 
YN 
R4 R9 
R5 R8 
R6 R7
Patent AU-2021204287-A1 (AU)
Title: Spinal alignment and securement
Inventor: ROGER GREGORY JAMES
IPC: A61B17/70
Filed: 2021-06-24
Abstract: A surgical connection device for a spine is provided, wherein a first spinal rod is configured 
to fix a group of first vertebrae together at a first lateral side of the spine and a second spinal 
rod is configured to fix the group of first vertebrae together at a second lateral side of the 
spine. The surgical connection device includes an elongate stabilization member; one or 
more anchor arms, each of the one or more anchor arms having a first end connected to a first 
portion of the elongate stabilization member and a second end configured to connect to the 
group of first vertebrae; and one or more first control arms each having a first end connected 
to a second portion of the elongate stabilization member and a second end configured to 
connect to at least one second vertebra of the spine, the at least one second vertebra not being 
fixed to the first spinal rod or the second spinal rod, nor connected by the surgical connection 
device to any other vertebra of the spine except via the one or more control arms. The first 
end of the one or more anchor arms connects to the first portion of the elongate stabilization 
member at a connection position that is medial and posterior of the first and second rods.
Patent AU-2021204702-A1 (AU)
Title: A method of gaming, a gaming system and a game controller
Inventor: BRAMBLE PAUL FRANCIS JASON
IPC: A63F9/24
Filed: 2021-07-05
Abstract: A method of gaming comprising conducting one or more paid 
5 game rounds initiated in response to the payment of a 
wager by a player and a series of one or more free game 
rounds initiated in response to a free game series trigger 
event, the method comprising: in each paid game round, 
selecting a set of paid game round symbols for display to 
10 the player, determining a paid game round outcome based on 
the selected symbols, and incrementing a jackpot by a paid 
game jackpot increment; in each free game round, selecting 
a set of free game round symbols for display to the 
player, determining a free game round outcome based on the 
15 selected symbols, and incrementing the jackpot by a free 
game jackpot increment; and awarding the jackpot on the 
occurrence of a jackpot award event.  
17846391 1 (GHMatters) P76957.AU.6 5/C7/21
Patent AU-2021220196-A1 (AU)
Title: Methods of activating regulatory T cells
Inventor: WONG HING C
IPC: C07K14/745
Filed: 2021-02-11
Abstract: Provided herein are methods of stimulating or increasing the proliferation of a T
Patent AU-2021226896-A1 (AU)
Title: Recessing smart quick connect devices
Inventor: KOHEN RAN ROLAND
IPC: H01R33/00
Filed: 2021-03-01
Abstract: A fixture is sized to be inserted into an electrical junction box having a socket. The fixture has a plug with conductive terminals that are mateable with the socket to connect the fixture to an electrical signal connected to the socket. An end of the fixture with the plug is inserted into the junction box to mate with the socket. A release latch extends from the plug so that an end of the latch is not recessed within the junction box, and can be pushed to release the plug and fixture for removal. The socket is attached to extension arms that are attachable to the junction box, so that the socket can be positioned at the correct height within the box to properly mate with the plug of the fixture after insertion.
Patent AU-2021235803-A1 (AU)
Title: Purine compounds for treating disorders
Inventor: WILLIAMS MARK
IPC: A61P25/00
Filed: 2021-03-09
Abstract: Substituted purine compounds of formula (I)-(III) and salts thereof act as adenosine A2a receptor (A2aR) antagonists for cancer immunotherapy, depression, anxiety, multiple sclerosis, NASH, scleroderma, ADHD, Alzheimer's 5 and Parkinsons. Pharmaceutical compositions comprising such compounds, and methods of their use in treating depression are also taught.