baber/WOPTO huggingface dataset:
Patent CA-2614935-A1 (CA)
Title: Methods of detecting and treating acute kidney injury
Inventor: HAMID RABB
IPC: G01N33/00
Filed: 2006-07-20
Abstract: We disclose a new and useful biomarker for acute kidney injury (i.e., AKI), renal ischemia reperfusion injury (i.e., IRI), ischemic acute kidney injury, and/or ischemic acute tubular necrosis (i.e., ATN). The biomarker is GRO-alpha (i.e., CXCLl, chemokine C-X-C ligand 1, GROl, GROa, MGSA, MGSA alpha, MGSA-a, NAP-3, SCYBl). We detected the biomarker using a QUANTIKINE(R) human GRO-alpha immunoassay (Cat. No. DGR00, R & D Systems, Minneapolis, MN). In addition, we disclose a method of treating lung damage.
Patent CA-2615377-A1 (CA)
Inventor: PATRICK PATRICK L
IPC: F25D3/00
Filed: 2006-06-16
Abstract: An apparatus and method are provided for rapidly cooling small volumes of fluids. The apparatus includes a plurality of cooling elements (60, 122, 200) each including a housing forming a sealable cooling fluid chamber which can house a cooling fluid. At least one spacer (84, 126, 204) is arranged to separate opposed cooling elements (60, 122, 200) and provide a separation distance between the opposed cooling elements (60, 122, 200). Each of the plurality of cooling elements (60, 122, 200) is arranged to be independently separable to allow ready assembly, disassembly, and cleaning. The plurality of cooling elements can include a stack of disc-shaped cooling elements (60) or concentric cylinders (122) that can be situated in a container and rotated by a motor (72, 180).
Patent CA-2615578-A1 (CA)
Inventor: MACIEL HELENA
IPC: C12N9/04
Filed: 2006-07-18
Abstract: L'invention concerne un polypeptide isolé ou purifié ayant une activité dans la voie de dégradation du MTBE, et/ou l'un au moins des intermédiaires cataboliques du MTBE, préférentiellement sélectionné dans le groupe consistant en le tert-butyl alcool (TBA), le 2-méthyl 1,2-propanediol (2 -M1, 2-PD), Phydroxyisobutyraldéhyde, l'acide hydroxyiso-butyrique (HIBA), ledit polypeptide étant sélectionné dans le groupe consistant en : a) un polypeptide comprenant une séquence en acides aminés sélectionnée dans le groupe consistant en SEQ ID NO :2, SEQ ID NO :4, SEQ ID NO :6, SEQ ID NO :8 ou SEQ ID NO :10, b) un polypeptide comprenant une séquence en acides aminés qui présente au moins 70 % d'identité, préférentiellement 75 %, 80 %, 90 %, 95 %, 98 % ou 99 % d'identité avec la séquence en acides aminés d'un polypeptide tel que défini en a), un polypeptide tel que défini en a) ou b) dont la séquence en acides aminés comprend une substitution, délétion, insertion, addition ou mutation d'un ou plusieurs acides aminés sur toute sa longueur.
Patent CA-2615583-A1 (CA)
Title: Aroma composition and method
Inventor: RITTER KARL A
IPC: A23L27/00
Filed: 2006-07-19
Abstract: An aroma composition comprising a first component selected from the group consisting of 4-hydroxy-2,5-dimethyl-3(2H)furanone, 3-hydroxy-2-methyl-4H-pyran-4-one, 2- ethyl-4-hydroxy-5-methyl-3(2H)furanone, 4-hydroxy-5-methyl-3(2H)furanone, a sulfur-containing analogue of any of the foregoing, and any combination, thereof; a second component selected from the group consisting of 2-furanmethanethiol, 2-methyl-3-furanthiol, 5-methyl-2- furanmethanthiol, and any combination, thereof; and a third component selected from the group consisting of 2-(1-mercaptoethyl)furan, 2-furanethanethiol, bis-(2-furfuryl) disulfide, a furanthiol disulfide, and any combination, thereof. The aroma composition can further include at least one alkylamine or benzylamine and/or a compound selected from the group consisting of hexenol, 1,5-octadien-3-one, methylthiopropionaldehyde, 2,3-diethyl-5-methylpyrazine, (E)-2-nonenal, (E,Z)-2,6-nonadienal, butanoic acid, 2 and 3-methyl butanoic acid, 2-methyl-3-(methyldithio)furan, dimethyltetrasulfide, 4-hydroxy-2-ethyl-5-methyl-3-(2H)furanone, m- cresol, 3-hydroxy-4,5-dimethyl-2-(5H)furanone, and any combination thereof.
Patent CA-2616099-A1 (CA)
Title: Nouveaux anticorps anti igf-ir et leur utilisation
Inventor: CORVAIA NATHALIE
IPC: C12N5/09
Filed: 2006-07-21
Abstract: L'invention porte sur de nouveaux anticorps anti IGF-IR (récepteur du facteur de croissance insulinomimétique de type I) se fixant spécifiquement à l'IGF-IR. L'invention porte également sur l'utilisation de ces anticorps comme médicament de traitement prophylactique et/ou thérapeutique de cancers surexprimant l'IGF-IR, stimulés soit par l'IGF1 et/ou l'IGF2, et de toute pathologie liée à la surexpression dudit récepteur. L'invention porte en outre sur des processus et des trousses de diagnostic de maladies liées à la surexpression de l'IGF-IR et/ou du récepteur hybride de l'IGF-I et de l'insuline.
Patent CA-2616800-A1 (CA)
Inventor: FUGLEVAND WILLIAM A
IPC: H01M8/04298
Filed: 2000-05-18
Abstract: Fuel cell power systems and methods of controlling a fuel cell power system are provided. According to one aspect, a fuel cell power system includes a plurality of fuel cells electrically coupled with plural terminals and individually configured to convert chemical energy into electricity; and a digital control system configured to at least one of control and monitor an operation of the fuel cells. Another aspect provides a method of controlling a fuel cell power system including providing a plurality of fuel cells individually configured to convert chemical energy into electricity; electrically coupling the plurality of fuel cells; providing a first terminal coupled with- the fuel cells; providing a second terminal coupled with the fuel cells; and coupling a digital control system with the fuel cells to at least one of monitor and control an operation of the fuel cells.
Patent CA-2621513-A1 (CA)
Title: Method and apparatus for automatically capturing multiple images of motor vehicles and other items for sale or auction
Inventor: PRUETT BOB
IPC: G08G1/09
Filed: 2006-04-03
Abstract: An automatic "photo booth" for capturing images of objects including but not limited to motor vehicles provides consistent and rapid image capture from multiple viewpoints. Ultrasonic sensors or other positional sensing devices are used to both position the object with the photo booth enclosure and calculate field of view parameters controlling digital cameras to provide appropriate image scaling/cropping at time of image capture. The enclosure provides automatic entry/exit door opening/closure and a controlled interior space to provide a controlled environment for image capture. Captured images may be rapidly uploaded to a server for electronic distribution over the World Wide Web or other appropriate network.
Patent CA-2623643-A1 (CA)
Inventor: BRADBERRY EDWIN
IPC: F16C35/00
Filed: 2006-10-13
Abstract: An idler assembly is disclosed for a shovel having a flexible track assembly.  In an embodiment, the idler assembly comprises an idler gear operatively associated with the track assembly; a sleeve; a shaft, sets of splines on the shaft and on the sleeve sized for engagement, and connectors at ends of the shaft; at least one bearing block forming a bore therethrough; at least one bushing liner disposed within at least one bearing block; and at least one retaining device for constraining the shaft from withdrawal from the bearing block. A method for retrofitting a shovel with an existing idler assembly is disclosed. In an embodiment, the method comprises positioning at least one bushing liner within a bore of at least one bearing block; attaching an idler shaft and an idler gear together; and positioning the idler shaft within the at least one bushing liner.
Patent CA-2624028-A1 (CA)
Inventor: GARNEAU JOCELYN
IPC: A47K3/02
Filed: 2008-03-17
Abstract: A shelf for a bathtub wall, of which the shelf has a planar body, at least two retention members extending from the planar body at, or near, one edge thereof, and a support member opposable to the retention members into abutment along the height of an opposite side of the bathtub wall, lower than the retention members. The surface of the bathtub shelf, can be provided with a marker-board type surface, to allow writing and drawing with erasable markers thereon.
Patent CA-2625262-A1 (CA)
Title: Modular genomes for synthetic biology and metabolic engineering
Inventor: HOLT ROBERT A
IPC: C12N1/21
Filed: 2006-10-12
Abstract: The invention provides methods and compositions for assembling a modular replacement genome in a host microorganism. After such assembly, the host organism's genome is inactivated or ablated to permit full control of host cellular functions by the replacement genome. A modular replacement genome comprises an assembly of nucleic acid fragments, or segments, derived from one or more natural organisms or from synthetic polynucleotides or from a combination of both. Such an assembly, or set, of segments making up a replacement genome comprises a substantially complete set of genes and regulatory elements for carrying out minimal life functions under predefined culture conditions. The invention provides modular genomes having modules that are amenable to facile replacement, deletion, and/or additions. Such modules may be synthetic polynucleotides and may be designed for controlling gene content, excluding of genes that encode inhibitors or otherwise undesirable competing enzymes that divert a host cell from desired metabolic/synthetic processes; modifying codon usage to maximize or minimize protein production;  modifying regulatory elements, including promoters, enhancers , repressors, activator, or the like, to modulate gene expression; balancing enzymatic and transport activities to optimize fluxes of substrates, intermediates, and products in metabolic pathways, and like objectives.
Patent CA-2625282-A1 (CA)
Title: Screening for modulators of metalation pathways for metalloproteins
Inventor: O'HALLORAN THOMAS V
IPC: G01N33/68
Filed: 2006-10-20
Abstract: The present invention is directed to methods for screening modulators of metalation pathways for the metalation of metalloproteins.
Patent CA-2626050-A1 (CA)
Inventor: SPRATT RAY STEVEN
IPC: G02C7/02
Filed: 2006-10-12
Abstract: An ophthalmic lens element (100) for correcting myopia in a wearer's eye is disclosed. The lens element (100) includes a central zone (102) and a peripheral zone (104). The central zone (102) provides a first optical correction for substantially correcting myopia associated with the foveal region of the wearer's eye. The peripheral zone (104) surrounds the central zone (102) and provides a second optical correction for substantially correcting myopia or hyperopia associated with a peripheral region of the retina of the wearer's eye. A system and method for dispensing or designing an ophthalmic lens element for correcting myopia in a wearer's eye is also disclosed.
Patent CA-2628735-A1 (CA)
Title: Stacked product array with enhanced visibility and recognition
Inventor: PICZON RHINN PAUL LUCERO
IPC: G06Q99/00
Filed: 2006-12-14
Abstract: A stacked product array possesses a plurality of individual products. Each individual product contains a visible graphic designed such that each visible graphic is different. However, when the individual products are aligned together at least one edge of each visible graphic matches at least one edge of at least one other visible graphic. So, when the individual products are stacked appropriately the combination of the visible graphics forms at least one continuous larger visible graphic whose area is larger than the average area of the visible graphics. A process for enhancing the visibility and recognition of a sacked product array is also provided.
Patent CA-2630251-A1 (CA)
Title: Microporous polyolefin membrane, its production method, battery separator and battery
Inventor: KAIMAI NORIMITSU
IPC: H01M50/494
Filed: 2006-11-22
Abstract: A microporous polyolefin membrane which comprises a polyethylene resin and in which (a) the shutdown temperature is 135~C or lower which is the temperature at which the gas permeability as measured with heating at a heating rate of 5 ~C/min reaches 1~105 sec/100 cm3, (b) the maximum degree of melt shrinkage in the transverse direction in the temperature range of 135-145~C is 40% or lower as measured by thermomechanical analysis at a load of 2 gf and a heating rate of 5 ~C/min, and (c) the meltdown temperature is 150~C or higher which is the temperature at which the gas permeability as measured with further continuous heating beyond the shutdown temperature reaches 1~105 sec/100 cm3 again.
Patent CA-2634618-A1 (CA)
Inventor: KRASNER NORMAN F
IPC: H04W64/00
Filed: 2000-01-24
Abstract: A method and apparatus is disclosed for measurement processing of Satellite Positioning System (SPS) signals. A  plurality of SPS signals from a corresponding plurality of SPS  satellites are received in an SPS receiver. The signal environment corresponding to the location in which the SPS  receiver is located is characterized to produce signal environment data. In one exemplary embodiment, an information source, such as a cellular network based database, is searched to retrieve the signal environment data given an approximate location of the GPS receiver. This approximate location may be specified by a location of a cell site which is in cellular radio communication with a cellular communication device which is co-located with the GPS receiver. One or more parameters related to signal characteristics of the satellite signals are defined. Threshold values for the parameters are determined using the signal environment data. Code phases corresponding to times of arrival of respective satellite signals from the plurality of satellites are measured. The data representing measured times of arrival are examined using threshold values for the parameters to produce a set of times of arrival from which a location fix for the GPS receiver is calculated. Other methods and apparatuses for other embodiments of the invention are also described.
Patent CA-2634855-A1 (CA)
Inventor: KITCHENS JACK C
IPC: G01N29/28
Filed: 2008-06-11
Abstract: An acoustic (sound or ultrasound) wave transmitter having a plurality of waveguides is described, and a method of making such a transmitter is described. Each waveguide may have a cladded core. The core may be a liquid such as water, alcohol or mineral oil.  Alternatively, the core may be a colloidal gel, such as gelatin dissolved in at least one of water, vinyl plastisol or silicone gel. The cladded core is capable of transmitting acoustic wave energy from a first end surface to a second end surface of the cladded core. The waveguides may be substantially fixed relative to each other by a binder. The binder may be formed by fusing the claddings together, potting a material between the waveguides and/or mechanically holding the waveguides.
Patent CA-2636669-A1 (CA)
Inventor: HILLMAN JOHN R
IPC: E04C3/30
Filed: 2007-01-05
Abstract: A construction beam useful for building bridges, commercial or industrial buildings, or the like has an elongated shell with an interior volume. A  conduit lies within the interior volume of the beam that has profile extending along a longitudinal direction of the beam. A compression reinforcement, fills the interior volume of the conduit. The beam may include a shear connection device, where one end of the shear connection device is positioned in the compression reinforcement, and the other end extends outwardly through the shell.
Patent CA-2637114-A1 (CA)
Title: Landscape edging strips
Inventor: ORTON DAVID S
IPC: A01G9/28
Filed: 2008-07-10
Abstract: A paver restraint comprises an extruded length of plastic that has a general cross-sectional shape of an ell or an angle iron, having a generally flat upwardly extending upper rectangular section and a lower or second rectangular section extending substantially perpendicularly from the lower edge of the upper section along the length of the upper section. A plurality of openings are formed in the lower rectangular section, with the openings being spaced from each other so that the legs of elongate, u-shaped staples can be received through adjacent slots or openings and driven into the ground to securely hold the paver restraint in position on the ground.
Patent CA-2637131-A1 (CA)
Inventor: KELLY RICHARD M
IPC: B32B33/00
Filed: 2008-07-10
Abstract: Climbing products containing rails decorated using veil products colored, patterned, painted or in combination with marking methods such as company names and logos and resin formulation designed to withstand exposure to UV radiation with minimal change in appearance which create specific appearances for applications, enhance weathering performance, and facilitate processing efficiency. A combination of a filler free resin or resin with filler and coated veil systems to create a synergistic weather resistance surface with self contained color, pattern, picture, logo or combination of said same for climbing products. A system for producing components at a rate of greater than 5 ft/min. Various methods, system, a ladder rail.
Patent CA-2638685-A1 (CA)
Title: Electronic trip units with limited read/write access
Inventor: JEGANATHAN SRINIVASAN
IPC: H01H73/00
Filed: 2008-08-14
Abstract: A method of limiting read/write access of information stored on an electronic trip unit, and an electronic trip unit with limited read/write access to information stored thereon, are disclosed herein. The method includes requesting a valid password on one of a communication port of the electronic trip unit and a display device of the electronic trip unit, receiving a password at a processor of the electronic trip unit in response to the request, determining if the received password is valid based on password information stored on a memory of the electronic trip unit, and limiting read/write access of information stored on the electronic trip unit based on the determination. The electronic trip unit is configured to perform the method.
Patent CA-2645271-A1 (CA)
Title: Communication means for communication with and remote activation of downhole tools and devices used in association with wells for production of hydrocarbons
Inventor: SORTVEIT HAEVAR
IPC: E21B47/18
Filed: 2007-03-19
Abstract: The present invention regards communication means for communicating wireless signals within a hydrocarbon well (101), the communication means comprising: at least one first communication means (107, 302) located in a first portion (108) within the well (101), the first communication means (107, 302) comprising at least one signal transmitter (107) or at least one signal transceiver (107, 302); and at least one second communication means (103, 301) located in a second portion (109) of the well (101), at least one of said first (107, 302) or second (103, 301) communication means being associated with an activation system (104) for a downhole device (102), wherein the transmitter (107, 301) being defined by a connector (801), a housing (802) and a flexible membrane (502), said flexible membrane being arranged for transferring to a well fluid oscillations provided by an actuator (501) located in a portion of the housing (802), the flexible membrane (502) being coupled to the actuator (501) via a coupler device (807) arranged to compensate for deflections of the membrane (502) as the transmitter (107, 301) is run into the well (101), whereby the coupler device (807) enables a controlled deflection of the membrane (502) without imposing damaging stresses to the actuator (501), but still providing an optimal transfer of oscillations from the actuator (501) to the membrane (502).
Patent CA-2646319-A1 (CA)
Inventor: MELTON-CELSA ANGELA
IPC: A61K39/108
Filed: 2007-04-20
Abstract: The invention is based on the discovery of the epitope in the Stxl protein for the 13C4 antibody. The invention features non-full length Stxl polypeptides that include the epitope for the 13C4 monoclonal antibody epitope. The invention also features methods of producing anti-Stxl antibodies specific for the 13C4 epitope of the Stxl protein. Additionally, the invention features methods for treating a subject having, or at risk of developing, a Shiga toxin associated disease (e.g., hemolytic uremia syndrome and diseases associated with E. coli and S. dysenteriae infection ) with a polypeptide that includes the 13C4 epitope or with an anti-Stxl antibody developed using the methods of the invention. Furthermore, the invention features the detection of Stxl in a sample using the antibodies developed using the methods of the invention.
Patent CA-2647670-A1 (CA)
Title: Synchronized wireless networked system
Inventor: HELLSTROM AKE
IPC: G01B21/20
Filed: 2008-12-22
Abstract: A sheet making system that has two or more separated nodes one of which may be a scanner sensing head and the other of which may be a scanner end column. Each node has a wireless system and receives power from a common AC source. Each node receives events data associated with the wireless system. Each wireless system has a circuit that obtains from the common AC power source an associated events data acquisition clock that is the same for all of the wireless systems to time synchronize to each other the associated events data signals at each of the two or more nodes. A central computer may be connected to the two or more nodes. The communication between the computer and each of the two or more nodes can be wireless or by a LAN or other mechanisms.
Patent CA-2648618-A1 (CA)
Inventor: ENDOU HITOSHI
IPC: C12P21/08
Filed: 2007-04-05
Abstract: A human antibody capable of binding specifically to CD98 which is CD98 originating in the cell membrane of cancer cells and forms a complex with a protein having an amino acid transport activity (for example, LAT1) and a functional fragment of the same. This antibody binds to CD98 forming a dimer with LAT1 on the surface of cancer cells, thus specifically attacks the cancer cells expressing CD98 by using an immunological system of ADCC or CDC and further inhibits the LAT1-mediated amino acid intake by the cancer cells, thus inhibiting the proliferation thereof. Accordingly, it is intended to provide an agent for preventing and treating caner which contains this antibody or a fragment of the antibody, acts on various cancers, is specific to cancer and shows no side effect.
Patent CA-2648966-A1 (CA)
Inventor: O'CHEE MILTON TERRENCE
IPC: B32B7/022
Filed: 2007-04-12
Abstract: L'invention concerne un élément (1) de construction convenant pour une utilisation en tant qu'élément structural dans des zones humides ou des terrasses extérieures. L'élément (1) de construction comporte un substrat rigide (2) présentant une face supérieure (3), cette première face (3) étant recouverte d'une résine (4) durcissable par rayonnement dans laquelle une couche de matériau (5) de renfort est au moins partiellement enrobée. Le matériau (5) de renfort et la résine (3) peuvent être appliqués séparément ou ensemble sur ladite première face (3) du substrat rigide (2) ou peuvent, dans certains cas, être appliqués aux deux faces. L'invention concerne également un appareil et un procédé de production de la feuille de construction.
Patent CA-2652235-A1 (CA)
Title: Methods for treating blood disorders
Inventor: PERRINE SUSAN P
IPC: A61K31/415
Filed: 2007-05-09
Abstract: Methods of treating blood disorders are described. The methods involve the use of a compound of the formulaes: Formula (I), Formula (II), Formula (III). The blood disorder is specifically anemia, thalassemia or sickle cell disease.
Patent CA-2655081-A1 (CA)
Title: Cholecystokinin-1 (cck1) receptor antagonists in the treatment of gastrointestinal and related disorders
Inventor: ROVATI LUCIO CLAUDIO
IPC: A61P1/00
Filed: 2007-06-12
Abstract: Cholecystokinin-1 (CCK1) receptor antagonists and the combination of CCK1 receptor antagonists and proton pump inhibitors (PPI) for the treatment of patients suffering from gastrointestinal or related disorders that have failed to completely respond to conventional acid suppression therapy.
Patent CA-2656462-A1 (CA)
Inventor: STEINBRENNER ULRICH
IPC: C09K23/00
Filed: 2007-07-17
Abstract: The invention relates to a composition used to produce foams, in particular for the extraction of petroleum and natural gas.