baber/WOPTO huggingface dataset:
Patent PT-1207818-E (PT)
Title: Floating phakic refractive lens design for preserving eye dynamics
Inventor: ZHOU STEPHEN Q
IPC: A61L27/00
Filed: 2000-08-29
Abstract: Phakic refractive lens (PRL) for correcting myopia or hyperopia are disclosed. The lens is implanted in the posterior chamber of the eye, with no permanent point of fixation, such that it floats between the patient's iris and natural lens. The lens corrects refractive errors in the eye, while maintaining the fluid dynamics of the eye and not causing stress or damage to eye structures. The lenses are made from a flexible material (such as those having a hardness of from about 20 to about 50 Shore A), having a specific gravity of from about 0.9 to about 1.2 g/cm<3>, and have a mass per unit area of from about 0.03 to about 0.30 mg/mm<2>. The method for using those lenses and surgical kits including those lenses are also disclosed.
Patent PT-1240337-E (PT)
Title: Methods and compositions for prolonging elimination half-times of bioactive compounds
Inventor: DENNIS MARK S
IPC: C07K1/04
Filed: 2000-12-22
Abstract: Peptide ligands having affinity for IgG or for serum albumin are disclosed. Also disclosed are hybrid molecules comprising a peptide ligand domain and an active domain. The active domain may comprise any molecule having utility as a therapeutic or diagnostic agent. The hybrid molecules of the invention may be prepared using any of a number techniques including production in and purification from recombinant organisms transformed or transfected with an isolated nucleic acid encoding the hybrid molecule, or by chemical synthesis of the hybrid. The hybrid molecules have utility as agents to alter the elimination half-times of active domain molecules. Elimination half-time is altered by generating a hybrid molecule of the present invention wherein the peptide ligand has binding affinity for a plasma protein. In a preferred embodiment, a bioactive molecule having a short elimination half-time is incorporated as or into an active domain of the hybrid molecules of the invention, and the binding affinity of the peptide ligand domain prolongs the elimination half-time of the hybrid as compared to that of the bioactive molecule.
Patent PT-1265479-E (PT)
Title: Methods for gamete production in birds
Inventor: PARDUE SAMUEL L
IPC: C12N5/076
Filed: 2001-03-23
Abstract: The present invention provides methods for the production of avian gametes, comprising reducing endogenous primordial germ cells (PGCs) in a recipient bird in ovo and introducing donor primordial germ cells from another bird into the recipient bird in ovo. The present invention further provides a method of increasing the ratio of male offspring from a female bird, comprising reducing endogenous PGCs in the female bird in ovo, introducing donor PGCs from another bird into the female bird in ovo, and incubating the female bird to hatch. The female bird is raised to sexual maturity and bred to produce a plurality of eggs having a higher proportion of male eggs than in the absence of the inventive methods. In some embodiments, the donor PGCs are from a different species than the recipient bird. In preferred embodiments, endogenous PGCs are reduced using busulfan.
Patent PT-1290006-E (PT)
Title: Combinatorial production of nucleotide and nucleoside (xitp) analogues
Inventor: MARLIERE PHILIPPE
IPC: C07H19/056
Filed: 2001-06-13
Abstract: Hydrazide-substituted nucleoside or nucleotide analogs (I) are new. Nucleoside or nucleotide analogs of formula (I) are new. [Image] R 1H; mono-, di- or tri-phosphate group; or protective group such as DMT; R 2, R' 2H, OH, phosphoramidite (or derivative), H-phosphonate or chain terminator T; R 3, R' 3H, OH, halo, 1-6C alkyl or OR 5; R 51-6C alkyl; R 45-membered heterocycle of formula (a) (e.g. pyrrole, pyrazole, imidazole, 1,2,4-triazole or tetrazole), 6-membered heterocycle (preferably of formula (b)) or purine analog of formula (c), (a)-(c) being bonded to the sugar residue at N and to E at C; E : optionally substituted, saturated or unsaturated spacer arm comprising 0-20C and optionally heteroatoms; X : CH, CR 6, or N; R 6halo, 1-6C alkyl, OR 7or SR 7; R 71-6C alkyl; Y 1NH 2, N=C(Z 1)(Z 2) or NH-CHZ 1Z 2; Y 2, Y 3H, OH, O, NH 2, halo, amine, amido or 1-6C alkyl; Z 1, Z 2H or organic group. [Editor's note: DMT is not defined in the specification.] Independent claims are included for: (i) the preparation of (I); (ii) libraries of compounds (I); (iii) nucleic acids (II) containing at least one compound (I). (iv) a method for identifying compounds capable of introducing a mutation into a nucleic acid, by incorporating (I; Y = NH 2) in a synthetic oligonucleotide, reacting with an aldehyde or ketone (or a library of aldehydes and/or ketones) optionally followed by reduction, replicating the oligonucleotide using a polymerase (specifically an exo-DNA polymerase) and determining whether a mutation has been introduced into the newly synthesized strand; (v) a method for point mutation of a nucleic acid, by preparing a synthetic oligonucleotide containing at least one compound (I) and replicating as in (iv); (vi) a method for random mutation of a nucleic acid involving using a reaction mixture containing at least one compound (I) for the amplification of a nucleic acid; (vii) a method for identifying a compound capable of inhibiting a polymerase (specifically a reverse transcriptase or kinase), by testing the activity of the enzyme in presence of at least one compound (I); (viii) a method for identifying a compound capable of inhibiting viral reverse transcriptase, by testing the effect of at least one compound (I) (in the form of a nucleoside analog) on infected cells; and (ix) a kit for the amplification and/or detection of a target nucleic acid, containing (I) or (II). ACTIVITY : Virucide; cytostatic. MECHANISM OF ACTION : Polymerase inhibitor; reverse transcriptase inhibitor; nucleotide kinase inhibitor; antisense nucleic acid.
Patent PT-1386116-E (PT)
Inventor: CLEVINGER NORMAN R
IPC: B21C37/15
Filed: 2002-04-17
Abstract: An improved heat transfer tube and a method of formation thereof. The inner surface of the tube has a primary set of fins and an intermediate sets of fins positioned in the areas between the primary fins and at an angle relative to the primary fins. While intermediate fins may be used with primary fins arranged in any pattern, in a preferred embodiment of the inner surface tube design, the intermediate fins are positioned relative to the primary fins to result in a grid-like appearance. Tests show that the performance of tubes having the intermediate fin designs of the present invention is significantly enhanced. A first set of rollers creates the primary and intermediate fin designs on at least one side of a board. A second set of rollers may be used to further enhance the performance. After the desired pattern has been transferred onto the board with the rollers, the board is then formed and welded into a tube, so that, at a minimum, the inner surface design of the resulting tube includes the intermediate fins as contemplated by the present invention.
Patent PT-1510332-E (PT)
Title: Method of producing containers from a flexible material
Inventor: HOFMEYER DIETER
IPC: B31B35/00
Filed: 2004-08-11
Abstract: Production of containers (B), especially bags, made of flexible material comprises arranging an upper flat web above a lower flat web (2) and conveying both webs in alignment. The upper web is divided into three upper web strips (3-5). The central strip (4) covers the central strip region of the lower web between the subsequent container rows. V-shaped folded continuous base strips of flexible material forming the subsequent container base are placed between the outer edges of the outer upper web strips (3, 5) and the lower web. The outer edges are aligned with the outer edges of the upper and lower webs. Longitudinal (10) and transverse connecting seams (11) for the base or side seal of the container and longitudinal connecting seams (13, 14) for connecting the central upper web strip to the central strip region of the lower web are attached. Transverse perforations (12) extending to the central strip region of the lower web are produced for lateral separation of the containers.
Patent PT-1500675-E (PT)
Title: Methods and compositions for protecting polymers from uv light
Inventor: SAMUELS SARI-BETH
IPC: B29C48/305
Filed: 1999-03-30
Abstract: A polymeric article, such as an extruded or molded article or a biaxially oriented tape of film, and a method of stabilizing such a polymeric article to protect the article from degradation due to exposure to UV light. The article is formed by blending a polymeric material with from about 50 to about 5,000 ppm of at least one ortho hydroxyl tris-aryl triazine light absorber and from about 500 ppm to about 1.25 percent of at least one oligomeric, polymeric, or high molecular weight HALS having a molecular weight of at least about 500, wherein the weight ratio of HALS to triazine light absorber is from about 3:1 to about 20:1, to form a stabilized polymeric composition, and forming an extruded or molded article or a biaxially oriented tape or film from the stabilized polymeric composition.
Patent PT-1631182-E (PT)
Title: Multifunctional electric cleaning apparatus
Inventor: FOLLEGOT RODOLFO
IPC: A47L5/24
Filed: 2004-05-19
Abstract: An electric cleaning apparatus ( 10 ) having a suction body ( 11 ), which is provided at one end with a suction aperture ( 13 ) connected to a suction drive member arranged inside the suction body ( 11 ), and to which a terminal suction element ( 32 ) is able to be selectively associated. The electric cleaning apparatus ( 10 ) includes tubular members ( 16, 21 ) pivoted on the suction body ( 11 ) and able to be selectively rotated with respect to the latter in order to define a first operating configuration, wherein the tubular members ( 16, 21 ) are arranged on the opposite side with respect to the suction aperture ( 13 ) in order to function as a remote handgrip for the suction body ( 11 ), and a second operating configuration, wherein the tubular members ( 16, 21 ) cooperate with the suction aperture ( 13 ) in order to function as an extension for the terminal suction element ( 32 ).
Patent PT-1656842-E (PT)
Title: Simulated cigarette which is designed to help quell tobacco addiction
Inventor: ANTONIO MARTINEZ FERNANDEZ JOSE
IPC: A24F42/20
Filed: 2004-07-21
Abstract: The invention relates to a simulated cigarette which is designed to help quell tobacco addiction. The invented simulated cigarette consists of a cylindrical body (1) which is made from a plastic material. The aforementioned cylindrical body contains: an inner plug (6) close to one of the ends thereof, natural essences (5) which are arranged next to a filter (7), and a secondary filter (4) having an extended inner diameter (2), to which a tip (3) is connected.
Patent PT-1680137-E (PT)
Title: Macrocyclic carboxylic acid and acylsulfonamide compound as inhibitor of hcv replication
Inventor: CONDROSKI KEVIN RONALD
IPC: A61K/
Filed: 2004-10-13
Abstract: The present invention provides compounds of the general formulas I-IX, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The present invention further provides treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.
Patent PT-1759966-E (PT)
Title: Fixture for bicycle saddle
Inventor: SINGENBERGER ROLF
IPC: B62J1/08
Filed: 2005-08-31
Abstract: The fastener has a saddle fastener (6) that is connected with a saddle carrier (4), and a holding down device (3) that is guided by a longitudinal slot of the carrier. The down device is connected with the fastener by an actuator that is adjustable by a screw thread. Adjusting mechanisms (8, 8`) connect the pulling unit and down device with each other and adjust relative to each other. The mechanisms adjust a straddle unit (7) against a saddle pipe (2) and immovably clamp the fastener against the carrier, where the saddle pipe is made of fiber-reinforced plastic.
Patent PT-1827136-E (PT)
Title: Formulation for oral administration having a health-promoting effect on the cardiovascular system
Inventor: ROVATI LUIGI ANGELO
IPC: A23L1/30
Filed: 2005-09-20
Abstract: Composition for oral administration, having a health-promoting effect on the cardiovascular system, comprising as active principles a policosanol or a mixture of policosanols, red yeast and an agent selected from astaxanthin and folic acid, preferably in combination with coenzyme Q10. The composition can be used in particular for the preparation of food supplements having health-promoting effects, such as eulipidaemic effect, correction of homocysteinaemia, antioxidant action and a protective effect on the vasal endothelium.
Patent PT-1762145-E (PT)
Title: Texturized cellulosic and lignocellulosic materials and compositions and composites made therefrom
Inventor: MEDOFF MARSHALL
IPC: B29B15/08
Filed: 2000-06-22
Abstract: Texturized cellulosic or lignocellulosic materials (e.g., texturized polycoated paper), and compositions and composites made therefrom, are disclosed.
Patent PT-1903849-E (PT)
Title: Apparatus and method for cooling a space in a data center by means of recirculation air
Inventor: MATSER PEDRO
IPC: F28D19/04
Filed: 2007-09-06
Abstract: An apparatus for cooling an air humidity- and temperature-conditioned space in a data center in which ICT and/or telecom equipment is arranged. The space is cooled using air flow that recirculates in the space. The apparatus is characterized in that the air stream heated by the equipment is supplied as a first air stream to an air-to-air heat exchanger designed as a heat wheel, in which the first air stream is cooled by means of a separate second air stream.
Patent PT-2055215-E (PT)
Title: Apparatus and method for preparing milk under various temperature and consistency conditions in a coffee machine for forming various types of beverages
Inventor: COCCIA ANDREA
IPC: A23P30/40
Filed: 2007-10-08
Abstract: A method for preparing hot milk in a coffee machine using fluid concentrated milk comprising the steps of: diluting a predetermined amount of concentrated milk with a corresponding predetermined amount of cold water; conveying the amount of cold diluted milk into the chamber (33) of a frothing device (17); conveying an amount of steam, predetermined depending on the temperature to be reached in the amount of milk, to the same chamber (33) of the frothing device (17); transferring to said amount of liquid milk the condensation heat of the amount of steam, obtaining in this way heating of the amount of milk to the desired temperature.
Patent PT-2062898-E (PT)
Title: Spirocyclic cyclohexane derivatives
Inventor: ENGLBERGER WERNER
IPC: A61K31/407
Filed: 2003-11-05
Abstract: Spiro-((4-amino-cyclohexane)-1,1'-1',3',4',9'-tetrahydropyrano-(3,4-b)-indole) derivatives (I) are new.  Spiro-cyclic cyclohexylamine derivatives of formula (I), optionally in the form of racemates, pure stereoisomers (especially enantiomers or diastereomers) or their mixtures in all proportions, including free bases, free acids, salts (specifically acid or base addition salt) or solvates (specifically hydrates), are new.  R1, R2  =  H, optionally unsaturated, optionally mono- or polysubstituted 1-4C alkyl or CHO;  R3  =  -(CH2)n-Aryl;  n  =  0-2;  R4  =  H, optionally unsaturated, optionally mono- or polysubstituted 1-3C alkyl or -CO-(CH2)m-H;  m  =  0-2;  R5 - R8  =  H; 1-5C alkyl or 1-3C alkoxy (both optionally unsaturated and optionally mono- or polysubstituted); or halo, OH, SH, SMe, OMe, NH2, COOH, COOMe, NHMe, NMe2 or NO2.
Patent PT-2141287-E (PT)
Title: Method of constructing a retaining wall
Inventor: SINNER UDO
IPC: E02D29/02
Filed: 2009-06-17
Abstract: The method involves washing a rear side of load distribution-cavities (8), and arranging wall holes (9, 10) in the load distribution-cavities through a retaining wall (1). A load distribution unit is formed in the load distribution-cavities by filling with mortar. The load distribution unit is anchored by a base anchor (5), and anchor rods are inserted into the wall holes. Ends of the anchor rods are anchored to the load distribution unit, where the ends passes into the load distribution-cavities, and the wall holes are injected with the mortar.
Patent PT-2322174-E (PT)
Title: Combined use of valsartan and calcium channel blockers for therapeutic purposes
Inventor: GASPARO MARC DE
IPC: A61P9/12
Filed: 1999-07-09
Abstract: The invention relates to a method for the treatment or prevention of a condition or disease selected from the group consisting of hypertension, (acute and chronic) congestive heart failure, left ventricular dysfunction and hypertrophic cardiomyopathy, myocardial infarction and its sequelae, supraventricular and ventricular arrhythmias, atrial fibrillation or atrial flutter, atherosclerosis, angina (whether stable or unstable), renal insufficiency (diabetic and non-diabetic), heart failure, angina pectoris, diabetes, hypertension in patients with NIDDM, secondary aldosteronism, primary and secondary pulmonary hyperaldosteronism, primary and pulmonary hypertension, renal failure conditions, such as diabetic nephropathy, glomerulonephritis, scleroderma, glomerular sclerosis, proteinuria of primary renal disease, and also renal vascular hypertension, diabetic retinopathy, the management of other vascular disorders, such as migraine, Raynaud's disease, luminal hyperplasia, cognitive dysfunction (such as Alzheimer's), and stroke, comprising administering a therapeutically effective amount of combination of (i) the AT 1 -antagonists valsartan or a pharmaceutically acceptable salt thereof and (ii) a Calcium channel blocker or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier to a mammal in need of such treatment and to corresponding pharmaceutical combination composition.
Patent PT-2298766-E (PT)
Title: Pharmaceutical formulations comrpising a substituted pyridine derivative
Inventor: ROTTLAENDER MARIO
IPC: A61K31/5377
Filed: 2006-03-02
Abstract: The present invention relates to pyridine derivatives of the general formula (I) and their use as openers of the KCNQ family potassium ion channels for the treatment of CNS disorders.
Patent PT-652002-E (PT)
Inventor: WILLIAMS DANIEL CHARLES
IPC: A61K31/4535
Filed: 1994-10-13
Abstract: A method of inhibiting cartilage degradation comprising administering to a human or other mammal in need of treatment an effective amount of a compound having the formula <CHEM>     wherein R<1> and R<3> are independently hydrogen, -CH3, <CHEM>  or <CHEM>  wherein Ar is optionally substituted phenyl; R<2> is selected from the group consisting of pyrrolidino and piperidino, a pharmaceutically acceptable salt or solvate thereof.
Patent PT-692306-E (PT)
Inventor: LEGENDRE OLIVIER
IPC: C01B17/16
Filed: 1995-07-12
Abstract: Catalyst for treatment of gases contg. sulphur cpds. and/or for hydrolysis of organic sulphur cpds., consisting essentially of catalytically active alumina contg. sodium in an amt. of 1200-2700 (1500-2500) ppm Na2O by wt.
Patent PT-843693-E (PT)
Inventor: KLUTH HERMANN
IPC: C08G18/10
Filed: 1996-08-01
Abstract: Described is an NCO-group-containing polyurethane prepolymer madefrom polyisocanyates and polyols derived from natural oils. The invention is characterized in that the polyol is obtained by transesterification in the presence of basic lithium compounds. Together with a tertiary amine used to accelerate the moisture curing, the storage stability is thus increased considerably. Up to 4.0 mmol of the lithium compound is used per kilogram of polyol, and 0.1 to 2.0% by wt. of the amine, relative to the total weight of the composition, is used as the accelerator. The polyurethane prepolymer is suitable not only for the production of adhesives but also for the production of foamed materials, in particular those dispensed from throw-away pressure vessels.
Patent PT-858646-E (PT)
Inventor: BREIDER JAKOB
IPC: G06F3/02
Filed: 1996-10-23
Abstract: PCT No. PCT/NL96/00412 Sec. 371 Date Jul. 8, 1998 Sec. 102(e) Date Jul. 8, 1998 PCT Filed May 1, 1997 PCT Pub. No. WO97/15909 PCT Pub. Date May 1, 1997A workstation comprising a keyboard for inputting data, a braille reading line having a number of braille cells located side by side, and a first switch device comprising a number of switch elements located side by side, wherein the first switch device is arranged in or parallel to the braille reading line, and wherein the workstation further comprises a second switch device comprising number of switch elements located side by side, wherein the second switch device is arranged in or parallel to the braille reading line, so that the first and the second switch device can each be operated by a visually handicapped person without the orientation of the hand relative to a braille cell of the braille reading line being lost.
Patent PT-893047-E (PT)
Inventor: LEGRAND EMMANUEL
IPC: A01D34/01
Filed: 1998-07-20
Abstract: Tangential jets in hubs rotated by jet reaction replace or, optionally supplement metal or plastic cutters of wheeled or user-carried machines of the prior art. User-carried machines have a ground-level hub (5) freely rotating on a fixed tube (1). Water (2), pumped (3) through the tube from a reservoir (4) at waist level, issues (7) from generally tangential hub nozzles (6). The reaction forces spin the hub. A small IC engine or electric motor powers the pump. Optionally a mains water connection replaces pump and reservoir. A deflector shields the operator's feet. Controls are located on hand-grips (8). The machine is optionally carried on a shoulder sling. For lawn mowing, one or more hubs are mounted under a push-along canopy supporting pump and reservoir. Optionally hubs have cutter blades with water channels ending in tangential tip nozzles. Optionally also, abrasives, e.g. fine sand, glass or marble, particles are drawn by venturi action into the water flow to improve cutting performance.
Patent PT-974055-E (PT)
Inventor: GERDIL CATHERINE
IPC: C12Q1/70
Filed: 1998-04-03
Abstract: The invention concerns a method for determining, in a composition containing different species of types of live viruses, the amount of viruses of each type or species, consisting in the following steps: propagating viruses of each type or species on cells permissive to the viruses but not inducing viral interference, assaying each type or species of virus using a specific monoclonal antibody.
Patent PT-1005598-E (PT)
Inventor: MERKEL GERALD
IPC: E04G7/30
Filed: 1998-08-18
Abstract: A scaffolding system includes tubular columns (3) and horizontal and/or diagonal crossbars (1,2). One or more scaffolding joints (4) are arranged on each tubular column (3) and placed above and at a distance from each other. Connecting elements (1,2) are engaged with the joints nots. The tubular columns includes wedge-shaped pockets for wedge shaped plug in elements forming joints (4) and connecting elements (1,2), the wedge-shaped plug in elements (5) are arranged on the ends of the crossbars and engage with the wedge pockets (6) of varying geometry. The horizontal connecting elements (1) are mounted via above-mentioned linkage of the wedge-shaped plug-in element (5) and the wedge pocket. The diagonal crossbars (2) are mounted by means of wedge heads (7) which are arranged on each side of a diagonal brace (2.1) and are slid over the wedge pocket (6) of the tubular column (3) via the receiving opening located in the small front face lies in a flat position.