baber/WOPTO huggingface dataset:
Patent CA-2708233-A1 (CA)
Inventor: HAMAMOTO HIDETOSHI
IPC: A61K31/407
Filed: 2008-12-09
Abstract: Disclosed is a tape preparation comprising etodolac in an ionic liquid form, which has high transdermal absorbability. Etodolac is reacted with an organic amine compound to produce an ionic liquid of etodolac. By using the ionic liquid, it becomes possible to increase the transdermal absorbability of etodolac. Further for the purpose of enhancing the transdermal absorbability and the tissue penetration ability of an ionic solution of etodolac, the composition of an organic solvent system for the ionic solution of etodolac is investigated, and it is found that a mixed solvent of an alcohol and an ester (1:2 to 2:1) is suitable as the organic solvent. Still further, an appropriate adhesion force can be achieved by properly selecting a softening agent. In this manner, a tape preparation having good transdermal absorbability can be prepared. The tape preparation can exert its pharmacological efficacy rapidly, and is therefore extremely effective for the teatment of a chronic pain such as rheumatoid arthritis, osteoarthritis and lumbago, an inflammatory diseases such as shoulder periarthritis and tendovaginitis, cervical syndrome, a pain induced by a surgery or an injury, or the like.
Patent CA-2708676-A1 (CA)
Inventor: GRANT MATTHEW BRUCE
IPC: E04F13/00
Filed: 2007-12-12
Abstract: A device (4) for positioning and supporting a cladding element (l0a) for attachment to a building structure (1). The device (4) has a first support member (90) adapted to receive a lower edge of a cladding element (10a) and an attachment member (5) adapted to be attached to the building structure (1). The first support member (9) is coupled for the attachment member (5) and extends from the attachment member (5) at an angle to the attachment member (5).
Patent CA-2714595-A1 (CA)
Inventor: RUSSELL STEPHEN JOHN
IPC: B32B7/02
Filed: 2009-02-20
Abstract: There is described a reinforced fibrous material comprising one or more nonwoven fabric layers entangled with a metallic mesh layer, methods for its preparation and uses thereof.
Patent CA-2719134-A1 (CA)
Inventor: MOSS JONATHON
IPC: A61K31/451
Filed: 2009-03-20
Abstract: Embodiments of the invention provide methods of treating a disorder or disease characterized by cellular proliferation and migration by co-administering a synergistically effective amount of an mTOR inhibitor and a µ-opioid receptor antagonist.
Patent CA-2719914-A1 (CA)
Inventor: FLYNN ROBIN L
IPC: C03B9/325
Filed: 2009-04-08
Abstract: A neck ring for molding a glass container neck finish that includes at least one closure attachment feature. The neck ring includes two semi-annular bi-met-al neck ring sections (12, 14), each consist-ing essentially of a neck ring insert (20, 22) of wear- resistant metal construction and a neck ring body (16, 18) of heat-conductive metal construction different from said wear--resistant metal construction and formed around said neck ring insert so as to embed it in said neck ring body. Each of said neck ring halves has a glass-contacting cavity face that includes a first surface portion (30, 32) formed by said inserts for molding the at least one closure attachment feature on the neck finish and a second surface portion (34, 36) formed by said bodies for molding portions of the neck finish excluding the at least one closure attachment feature.
Patent CA-2720669-A1 (CA)
Inventor: AUX EPAULES ARNAUD
IPC: A61F2/46
Filed: 2009-05-06
Abstract: A prosthetic acetabular cup inserter and impactor comprising an expandable annular cup engaging element to engage the inner surface of a cup to be inserted, expander means for expanding the cup engaging element which is connected to one end of a handle via a hollow or partly hollow extension portion, the other end of said handle is provided with an anvil, an elongate operating means located within said extension portion and connected to said cup engaging element, and means for moving said elongate operating means to pull said cup engaging means towards the expander means.
Patent CA-2722196-A1 (CA)
Title: A method for speech coding, method for speech decoding and their apparatuses
Inventor: YAMAURA TADASHI
IPC: G10L25/93
Filed: 1998-12-07
Abstract: Speech decoding and/or encoding method and/or apparatus for a speech code according to code-excited linear prediction (CELP). A linear prediction parameter code is obtained by encoding a linear prediction parameter from the speech code and likewise the linear prediction parameter is obtained by decoding the linear prediction parameter code. An adaptive code vector corresponding to the adaptive code concerning a decoding period is obtained from an adaptive codebook. An evaluated noise level is obtained from a gain of the adaptive code vector or pitch information corresponding to the adaptive code, which evaluated noise level is used to weight time series vectors forming an excitation code vector. During decoding the excitation code vector is obtained from a mathematical operation on the time series vector extracted from the excitation codebook and an operand based on a gain of the adaptive code vector. During encoding the excitation code is produced by comparing the speech with a coded speech formed from the adaptive code vector and the excitation code vector. Speech is synthesized during decoding using the linear prediction parameter and an excitation signal formed by weighted addition of the adaptive code vector and the excitation code vector.
Patent CA-2725643-A1 (CA)
Inventor: SIMEN BIRGITTE BINDERUP
IPC: C12Q1/70
Filed: 2009-06-29
Abstract: An embodiment of a method for detecting low frequency occurrence of one or more HIV sequence variants associated with drug resistance is described that comprises the steps of: generating cDNA  species from each RNA molecule in an HIV sample population; amplifying at least one first amplicon from the cDNA species, wherein each first amplicon comprises a plurality of amplified copies and is amplified with a pair of nucleic acid primers that define a locus of the first amplicon;  clonally amplifying the amplified copies of the first amplicons to produce a plurality of second amplicons wherein a plurality of the second amplicons comprise an immobilized population of substantially identical copies from one of the amplified copies of first amplicons; determining a nucleic acid sequence composition of the substantially identical copies from at least 100 of the immobilized populations in parallel on a single substrate; and detecting one or more sequence variants that occur at a frequency of 5% or less in the nucleic acid sequence composition of the at least 100 immobilized populations; and correlating the detected sequence variants with variation associated with HIV tropism.
Patent CA-2726647-A1 (CA)
Inventor: BRANT PATRICK
IPC: C08F210/00
Filed: 2009-06-19
Abstract: This invention relates to a polymacromonomer comprising at least one macromonomer and from 0 to 20wt%  of a C2 to C12 comonomer, wherein the macromonomer has vinyl termination of at least 70%, and wherein the polymacromonomer has: a) a g value of less than 0.6, b) an Mw of greater than 30,000 g/mol, c) an Mn of greater than 20,000 g/mol, d) a branching index (g')ViS of less than 0.5, e) less than 25% vinyl terminations, f) at least 70wt% macromonomer, based upon the weight of the polymacromonomer, g) from 0 to 20wt% aromatic containing monomer, based upon the weight of the polymacromonomer and h) optionally, a melting point of 50°C or more. This invention also relates to processes to make such polymacromonomers.
Patent CA-2727558-A1 (CA)
Inventor: LIEFTUCHT DIRK
IPC: B22D11/20
Filed: 2009-04-30
Abstract: The invention relates to a process for predicting the emergence of longitudinal cracks during the continuous casting of steel slabs, wherein the local strand temperature is measured by thermocouples distributed in the mould wall. In this process, the risk of the strand rupturing as a result of longitudinal cracking is assessed statistically taking into account the current temperature values measured by the thermocouples arranged in the mould, and on the basis of the temperature values determined when no cracks are present.
Patent CA-2728500-A1 (CA)
Inventor: BYNE RIAD JOHN
IPC: A43C11/24
Filed: 2009-06-18
Abstract: The present solution provides embodiments of a multi-part fastener and methods of use thereof to more efficiently and securely laces, such as for footwear and/or other wearable items. The multi-part fastener may be in the form of a two-piece clip used to secure laces of footwear. Each end of the clip may have one or more eyelets for traversal of and securing of a lace of the footwear. The lace may be attached to footwear, such as via eyelets of the footwear, Each end of the lace may traverse a row of eyelets of the footwear. Upon traversing a row of eyelets, each end may extend from an eyelet in an untied manner, such as an eyelet near or at the end of the row of eyelets. One end of the lace may be tied through the eyelets of a first part of the clip and the other end of the lace may be tied through the eyelets of a second part of the clip. To secure the end of the lace of the footwear to each other, the male end of the clip may be inserted into and secured by the female end of the clip. This provides tension between the ends of the laces and across the tongue of the footwear. To unfasten the ends of laces and remove the tension, the male end of the clip is released from the female end of the clip. In this manner, the fastening and unfastening of footwear laces is performed by engaging and disengaging the clip instead of repeatedly tying and untying the laces of the footwear. This may provide more consistent and repeatable tension and comfort to the wearer of the footwear while also making the processing of putting on and taking off footwear more convenient.
Patent CA-2730772-A1 (CA)
Inventor: KARL ULRICH
IPC: A01P7/04
Filed: 2009-07-27
Abstract: The invention relates to insecticide-impregnated nets of textile fibre which have a small mesh size, and also to the use thereof for protecting against pests.
Patent CA-2731523-A1 (CA)
Inventor: RADZIUNAS JEFFREY P
IPC: A61B17/34
Filed: 2011-02-10
Abstract: A surgical portal apparatus includes a portal housing, a portal member, and an elongated seal mounted within the portal housing. The portal housing defines a housing opening for reception of a surgical object and the portal member extends from the portal housing. The elongated seal includes an outer wall segment and an inner seal segment.  The outer wall segment has first and second ends that are mechanically coupled to the portal housing. The inner seal segment is disposed within the outer wall segment and depends radially inwardly relative to the longitudinal axis. The inner seal segment has inner surfaces that define a seal passage and is adapted to establish a substantial sealed relation with the surgical object. The outer wall segment includes a flexible material to permit deflection of the outer wall segment and corresponding movement of the inner seal segment in at least a radial direction with respect to the longitudinal axis.
Patent CA-2734348-A1 (CA)
Inventor: DANISHEFSKY SAMUEL
IPC: A61P35/00
Filed: 2009-07-13
Abstract: Glycopeptide conjugates, and methods of making and using such conjugates are disclosed. Certain glycopeptide conjugates comprise tumor associated carbohydrate antigens and peptide epitopes. Certain glycopeptide conjugates comprise cyclic peptide scaffolds that display carbohydrate antigens in a clustered fashion. The immunogenicity of select glycopeptide con-jugates is demonstrated.
Patent CA-2734658-A1 (CA)
Inventor: BECKER HAROLD L
IPC: E21B43/22
Filed: 2011-03-22
Abstract: A process for fracturing a subterraneous formation in the production of an oil well is described. The process steps include injecting an initial charge of a mixture, the mixture being formed from at least a water-insoluble adsorbent and at least one well treatment agent, into a well bore formed in the subterraneous formation so as to form a downhole matrix within the formation; injecting a solution comprised of an additional amount of the well treatment agent into the formation after the initial charge of the at least one well treatment agent has been substantially depleted; and then pressurizing the well bore for a time and under conditions sufficient to reactivate the downhole matrix in the formation, so that the treatment agent activity of the matrix is increased relative to the treatment agent activity of the matrix just prior to injecting the solution.
Patent CA-2734902-A1 (CA)
Title: Method and system enabling use of white space radio spectrum using an out of band control channel
Inventor: SINGH RAJENDRA
IPC: H04W4/021
Filed: 2009-06-11
Abstract: A system (10) and method (50) of dynamic allocation of spectrum for a communication device involves receiving (51) a user channel map (UCM) on a control channel that is outside the band of interest. The UCM can include at least boundary location information for one or more channel resources within a UHF band and communication parameters. The method can determine (52) at least an approximate location for the communication device, compare (56) the approximate location with the boundary location information, and determine (57) which channels can avoid co-channel and adjacent channel interference with licensed users and other unlicensed users based on the comparison, boundary location information, and the communication parameters. The UCM can further include communication parameters such as maximum allowable transmit power, duty cycle, and in use information by other unlicensed and licensed users. The boundary location information can include polygon endpoint calculations and associated technical communication parameters.
Patent CA-2736999-A1 (CA)
Title: Pest control for burrowing animals
Inventor: PASK MURRAY
IPC: A01N59/26
Filed: 2011-04-01
Abstract: A method of pest control for burrowing animals involves loading a machine-conveyed dispensing apparatus with a fumigant product, and using the machine to make one or more passes across an area of ground beneath which the burrow system is situated. A ground engagement tool of the dispensing apparatus is engaged in the ground to pass through or nearby sections of the burrow system, and fumigant product is dispensed into the ground behind a leading portion of the ground engagement tool. Fumigant is widely spread over the burrowed area of ground for effective results, while the human exposure and manual effort associated with conventional hand-placed fumigant techniques is greatly reduced.
Patent CA-2738751-A1 (CA)
Inventor: SMELCER JIM C
IPC: F24H1/28
Filed: 2009-07-06
Abstract: A water heating apparatus (10) uses a low range blower assembly (52) and a high range blower assembly (54), each providing a variable flow of premixed fuel and air to a burner assembly (42). Appropriate choice of the operating ranges of the blower assemblies can provide a high turndown ratio approximately equal to the product of the turndown ratios of each of the individual blower assemblies. Turndown ratios as high as 25:1 are achievable.
Patent CA-2739847-A1 (CA)
Inventor: SIKORA SASCHA
IPC: C09D5/18
Filed: 2009-10-08
Abstract: The invention relates to a method for determining shape changes of a workpiece made of steel or a steel alloy due to forming, in which a varnish is applied to the workpiece, the workpiece is formed and then an optical shape change analysis is carried out by measuring the applied varnish.  The object of providing a method for determining shape changes of a workpiece made of steel or a steel alloy, said method also being suitable for analyzing the shape change of a workpiece after hot forming, is solved according to the teaching of the present invention in that before the forming of the workpiece a varnish with an Al proportion of more than 30% by weight is applied to the workpiece, the workpiece is heated for forming to a hot forming temperature and the workpiece is cooled after or during the forming.
Patent CA-2740885-A1 (CA)
Title: Inhibiteurs d'heteroarylkinase a noyau fusionne
Inventor: DAR ARVIN
IPC: A61K31/519
Filed: 2009-10-16
Abstract: L'invention porte sur des composés hétéroaryles à noyau fusionné utiles dans une pluralité de procédés, comprenant la réduction de l'activité de certaines kinases et le traitement de certains états pathologiques.
Patent CA-2743760-A1 (CA)
Inventor: RITTER JASON
IPC: B60L7/10
Filed: 2011-06-20
Abstract: A regenerative brake system for converting kinetic energy of a moving vehicle into usable mechanical or electrical power is disclosed. The regenerative brake system includes a generator operably coupled to at least one of the vehicle wheels.  The system further includes a battery and a thermal storage system, each of which stores power generated by the generator until it can be efficiently used. The thermal storage system includes a heater that uses electrical power from the generator to vaporize a working fluid disposed within a storage tank. The thermal storage system further includes an expander to selectively expand the vaporized working fluid to convert heat from the working fluid into usable energy.
Patent CA-2746014-A1 (CA)
Inventor: NZIKE PHILIPPE
IPC: A61M5/24
Filed: 2009-12-09
Abstract: A drive mechanism for a medication delivery device (1) is proposed, the drive mechanism comprising a housing (13, 17, 40) having a proximal end and a distal end, a rotation member (21) which is adapted to be rotated in a first direction with respect to the housing during setting of a dose of a medication and to be rotated in a second direction with respect to the housing during delivery of the dose, the second direction being opposite to the first direction, a piston rod (12) which is adapted to be displaced in a distal direction with respect to the housing for delivering the dose, a drive member (20) which follows rotational movement of the rotation member in the second direction during delivery of the dose, and a stop member (26) which prevents ro-tational movement of the drive member with respect to the housing in the first direction during setting of the dose, wherein the ro-tational movement of the drive member in the second direction is converted into movement of the piston rod in the distal direction with respect to the housing. Furthermore, a medication delivery device is provided for.
Patent CA-2749422-A1 (CA)
Inventor: HODZA ERKAN
IPC: B23D77/04
Filed: 2010-02-23
Abstract: The main body (12) of a machine tool (10) comprises a plate seat (18) having a plate element (16) arranged thereon. The plate element (16) has at least one plate edge (38), which protrudes freely to the outside over the plate seat (18) and rests against a bottom support surface of the plate seat (18) . The plate element (16) can be fixed to the plate seat (18) by way of a bolt (20) extending through a bore hole in the plate element (16) . A first brace (22) for the plate element (16) is provided on the plate seat (18), said brace having a support surface (34) against which the plate element (16) rests non-positively with a lateral plate surface. A further brace (24) is designed on the plate seat (18) for a lateral plate surface of the plate element (16) to rest against non-positively. In order to adjust the plate edge (38) of the plate element (16), an adjustment device (30) is associated with at least one brace (22) and enables the brace (22) to be raised and lowered with respect to the bottom support surface of the plate seat (18) . A linear guide (50) is provided for said at least one brace (22), said guide absorbing the forces and torque occurring during the adjustment of the plate element (16) and introducing them into the main body (12) of the machine tool (10).
Patent CA-2755683-A1 (CA)
Inventor: PFEIFER ANDREA
IPC: A61P25/28
Filed: 2010-03-18
Abstract: The present invention is related to methods for the therapeutic use in the treatment of diseases and disorders where T-helper independent antibody responses are beneficial. In particular, the present invention relates to a method wherein these diseases and disorders above are treated in immunocompromised or autoimmune diseased animals or humans.   Even more particular the present invention relates to the treatment of Alzheimer's disease in immunocompromised or autoimmune diseased animals or humans or where inflammatory reactions need to be specifically avoided.
Patent CA-2759269-A1 (CA)
Title: P38 kinase inhibiting agents
Inventor: KOYAMA HIROO
IPC: A61K31/433
Filed: 2010-04-26
Abstract: Compounds described by the chemical formula (I) or pharmaceutically acceptable salts thereof: Formula (I); are inhibitors of p38 and are useful in the treatment of inflammation such as in the treatment of asthma, COPD, ARDS, rheumatoid arthritis, rheumatoid spondylitis, osteoarthritis, gouty arthritis and other arthritic conditions; inflamed joints, eczema, psoriasis or other inflammatory skin conditions such as sunburn; inflammatory eye conditions including conjunctivitis; pyresis, pain and other conditions associated with inflammation.
Patent CA-2761098-A1 (CA)
Title: System for assessing risk for progression or development of periodontitis for a patient
Inventor: LINDSKOG SVEN
IPC: G16Z99/00
Filed: 2009-05-08
Abstract: The invention relates to a method, system and a device for assessing the risk for periodontitis progression or for developing periodontitis, and a method, system and a device for prognosticating the outcome of a treatment procedure for treating periodontitis, on the basis of a risk score calculated on the basis of weight factors, which may be associated with numerical values, assigned to a plurality of measures corresponding to a plurality of predictors promoting periodontitis comprising host predictors, local predictors, and systemic predictors for periodontitis progression or for developing periodontitis for a patient. The invention provides among other things an objective tool that allows for preventive measures to be taken in time before severe and often irreversible damage caused by periodontitis has occurred, by taking into account the most important risk predictors promoting periodontitis, and in particular takes into account the synergy between these predictors. The invention also relates to a computer readable storage medium, on which there is stored a computer program comprising computer code adapted to perform one or more of the above-mentioned methods, and furthermore such a computer program.
Patent CA-2763334-A1 (CA)
Title: Flight management system with integrated tactical commands for use with an aircraft and method of operating same
Inventor: WALTER RANDY LYNN
IPC: B64D43/00
Filed: 2012-01-05
Abstract: A flight management system (24) for use in automatically generating a flight path trajectory (26) for an aircraft (10) is provided. The flight path trajectory including a plurality of waypoints (28) and a plurality of vectors (30) extending between each waypoint of the plurality of waypoints, the flight management system including a processor (302) is configured to calculate a first flight path trajectory (36) including an origin waypoint (40) and a destination waypoint (42), receive a tactical command indicating a change in flight trajectory, and calculate a second flight path trajectory (38) based at least in part on the tactical command, the calculated second flight path trajectory including a departure waypoint along the first flight path trajectory, an intercept waypoint (48) along the first flight path trajectory, and a departure vector from the departure waypoint (46) to the intercept waypoint.
Patent CA-2766621-A1 (CA)
Inventor: DYER JOHN COLLINS
IPC: C08G69/26
Filed: 2012-02-02
Abstract: The present invention relates to cationic polymers, such as polyaminoamide epichlorohydrin (PAE), that are derived from renewable resources and can be used to produce wet strength resins suitable for a variety of applications, such as in absorbent paper articles.