baber/WOPTO huggingface dataset:
Patent DK-0440146-T3 (DK)
Inventor: LITTLE MELVYN DR
IPC: C12N15/13
Filed: 1991-01-28
Granted: 1997-03-10
Abstract: Synthetic human antibody libraries are constructed by'generation of random sequences for the hypervariable regions under the restrictions (a) or (e), batch A or batch B according to Table 1 and subsequent insertion into an expression vector' (sic). Synthetic human antibody libraries can be produced by using almost randomly synthesised oligonucleotides coding for each of the three hypervariable regions in the variable parts of the heavy and light chains (regions CDR1, CDR2 and CDR3).
Patent DK-0444546-T3 (DK)
Inventor: MOCHIDA EI
IPC: C07D405/12
Filed: 1991-02-22
Granted: 1996-09-30
Abstract: The present invention relates to pharmaceutical compositions containing at least one of hydantoin derivatives as hypoglycemic as well as hypolipidemic agents. The present invention is based on the selection of a hydantoin which is bonded by a sulfonyl group to various substituents at the 1 - position of the hydantoin skeleton. The compounds of the present invention represent a satisfactory hypoglycemic as well as hypolipidemic activity. These compounds are extremely useful for the treatment and/or prevention of diabetes mellitus with or without hyperlipidemia. It is indicated that the compounds of the present invention are useful for the treatment and/or prevention of diabetic complications such as somatic or autonomic neuropathy, cataract, retinopathy, nephropathy or microangiopathy. It is also indicated that the compounds of the present invention are useful for the treatment and/or prevention of hyperlipidemia.
Patent DK-0527821-T3 (DK)
Inventor: MORSER MICHAEL JOHN
IPC: C12P21/02
Filed: 1991-04-09
Granted: 1997-12-15
Abstract: Novel soluble oxidation resistant thrombomodulin analogs are produced for various therapeutic and other uses, such as in thrombotic and vascular disease therapies. These analogs exhibit the characteristic therapeutic properties of native thrombomodulin, yet they are soluble and are not inactivated after they have been exposed to oxidants. Some of the analogs disclosed are multifunctional fusion proteins having both antithrombotic activity and some additional bioactivity.
Patent DK-0537189-T3 (DK)
Inventor: SORQVIST STIG
IPC: E04C3/29
Filed: 1991-05-27
Granted: 1995-07-31
Abstract: PCT No. PCT/SE91/00373 Sec. 371 Date Jan. 28, 1993 Sec. 102(e) Date Jan. 28, 1993 PCT Filed May 27, 1991 PCT Pub. No. WO91/19055 PCT Pub. Date Dec. 12, 1991.A method of erecting a foundation structure for a building substructure, in which joists including a horizontal web interconnecting upright side flanges on either side, are positioned butt end against butt end and are fixed in position at a distance of a few centimeters above a substratum. Gravel, macadam or other back fill material is then positioned against the external face of each side flange, whereupon concrete is poured into the joists and is allowed to partly flow downwards, through apertures formed in the joist webs, and onto the substratum.
Patent DK-0553256-T3 (DK)
Inventor: CAPY GILBERT
IPC: B65D85/00
Filed: 1991-10-24
Granted: 1994-11-28
Abstract: A wrapping for arbitrary objects is formed of a pleated sheet having sides disposed along curves of various shapes. A tape may be attached to the sheet for fixing the pleats and for closing the end openings formed when the sheet is trained around the object. The pleats may increase in size as they progress from one lateral edge to the other.
Patent DK-0506478-T3 (DK)
Inventor: CANTRELL BUDDY EUGENE
IPC: C07D413/12
Filed: 1992-03-27
Granted: 1997-10-20
Abstract: 3,4,4-trisubstitutedpiperidinyl-alkyl-carboxylates and intermediates for their preparation are provided. These piperidine-N-alkylcarboxylates are useful as peripheral opioid antagonists.
Patent DK-0526026-T3 (DK)
Inventor: MCGIBBON GRAEME
IPC: C09D11/10
Filed: 1992-07-10
Granted: 1996-01-29
Abstract: An aqueous composition suitable for use as a printing ink is provided which comprises an aqueous solution or emulsion of a film-forming polymer containing a titanium compound which is the reaction product of a titanium orthoester, a beta-diketone and a dihydric alcohol. Preferably the composition also contains a pigment or dye and other conventional printing ink additives. The titanium compounds enhance the adhesion and heat resistance properties of the compositions and in contrast to known additives do not lose their efficacy when the ink is stored for more than a few hours.
Patent DK-0530970-T3 (DK)
Inventor: PARKER FRED T
IPC: A61M25/00
Filed: 1992-07-29
Granted: 1996-02-26
Abstract: A flexible, kink-resistant, introducer sheath (10) for percutaneous vascular access. The introducer sheath includes a flat wire coil (23) with uniform spacing between the turns, which is compression fitted about an inner, lubricous material polytetrafluoroethylene tube (22). The introducer sheath further includes an outer tube (12) of a heat formable polyamide material which is heat formed and compressed through the spaces between the turns of the wire coil to mechanically connect to the roughened outer surface of the inner tube. The distal end (13) of the outer tube is tapered in a mould with additional polyamide outer tube material. The proximal end (15) of the sheath is flared for connection to a connector fitting. <IMAGE>
Patent DK-0512883-T3 (DK)
Inventor: BURNOUF NEE RADOSEVICH MIRYANA
IPC: A61K38/00
Filed: 1992-04-23
Granted: 1998-03-16
Abstract: The invention relates to a human Factor XI concentrate having high specific activity prepared using a process comprising a filtration-adsorption step and a single step of chromatography on cation exchange resin. The concentrate obtained is perfectly suitable for therapeutic use in replacement therapy in cases of Factor XI deficiency.
Patent DK-0585287-T3 (DK)
Inventor: WINTER GREGORY PAUL
IPC: G01N33/68
Filed: 1992-05-15
Granted: 2000-04-17
Abstract: The invention provides methods and kits for producing specific binding pairs (sbp) members. Populations of polypeptide chain components of sbp members are combined to form libraries of sbps displayed by secreted replicable genetic display packages (rgdp). At least one of the polypeptide chains is expressed as a fusion with a component of an rgdp which thereby displays that polypeptide chain at the surface of rgdp. At least one population of polypeptide chains is expressed from nucleic acid which is capable of being packaged using a component of an rgdp, whereby the genetic material of rgdps produced encodes a polypeptide chain. The methods enable production of libraries of multimeric sbp members from a very large number of possible combinations. In one embodiment of the invention a method employs "chain shuffling" in the production of sbp members of desired specificity for a counterpart sbp member. Selection procedures are also described.
Patent DK-0571815-T3 (DK)
Inventor: GZESH DAVID PAUL
IPC: C10N10/04
Filed: 1993-05-11
Granted: 1999-05-31
Abstract: Shaped, dust-free dry wire drawing compound lubricants having at least one reproducibly controlled dimension and methods for their preparation comprising the steps of conglutinating and pressure forming the lubricant composition.
Patent DK-0608849-T3 (DK)
Inventor: RONCHI CLAUDIO
IPC: G02B6/28
Filed: 1994-01-25
Granted: 1997-10-27
Abstract: The present invention relates to a device for generating several secondary light beams from one primary light beam, especially for a multiple-wavelength pyrometer. According to the invention, the primary light beam (1) is focused by a collecting optics unit (2) onto an input window (3) in a hollow sphere (4). The hollow sphere interior wall is coated with a diffuse-reflective layer, and windows (5, 6) distributed over the surface of this sphere are provided for the exit of the secondary light beams. <IMAGE>
Patent DK-0641701-T3 (DK)
Inventor: SCHUELMANN RAINER
IPC: B61D23/02
Filed: 1994-08-31
Granted: 1998-07-20
Abstract: An entry step for rail vehicles has at least one step which can be moved outwards in the region of the entry. In order to be able to adapt the entry to different heights of platforms or passenger waiting areas and/or to different distances from the platform or from the passenger waiting area, at least three steps (1, 2, 3) are provided, at least the lowest step (1) of which is constructed so as to be capable of moving out and the top step (3) of which is constructed so as to be capable of moving out and of being retracted.   <IMAGE>
Patent DK-0608954-T3 (DK)
Inventor: JENSMA KLAAS
IPC: A61B17/00
Filed: 1994-01-27
Granted: 1997-05-26
Abstract: In methods and apparatus for cooling surfaces, a pressurized liquid refrigerant is dispensed through a shaped member composed of an open celled foam. The method is particularly useful for localized freezing of a wart or other growth prior to its removal from skin of a human being or another animal. <IMAGE>
Patent DK-0648762-T3 (DK)
Inventor: MONN JAMES ALLEN
IPC: C07D403/12
Filed: 1994-10-13
Granted: 2001-07-30
Abstract: This invention provides novel bicyclic compounds (Bicyclo [3.30] odande derivatives) of formula I <CHEM> in which W, R<1>, R<2>, R<3>, n, m and p have the meanings given in the Specification, which are useful as excitatory amino acid receptor antagonists and in the treatment of neurological disorders. This invention also provides intermediates useful in the synthesis of excitatory amino acid antagonists.
Patent DK-0655543-T3 (DK)
Inventor: POIX RENE
IPC: E06B3/54
Filed: 1994-11-25
Granted: 1998-02-16
Abstract: The subject of the invention is an assembly for a mechanical joint, particularly by means of catching in a substantially vertical plane, of a plate, particularly of a window panel (pane) (4) on a carrying structure. The said joint permits a flexing movement of controlled amplitude for the said plate, with the aid of an articulated fastening system (10) permitting the rocking of the plate about its supporting point (P) on the said system. <IMAGE>
Patent DK-0781753-T3 (DK)
Inventor: BROSE DANIEL J
IPC: C07C49/697
Filed: 1994-03-16
Granted: 1999-10-11
Abstract: The sepn. of the enantiomers of 4-(3,4-dichlorophenyl) -3,4-dihydro-1(2H) -naphthalenone (I) comprises (a) contacting the enantiomers with a liq. mixt. of water and a solvent, this liq. contg. a substantially pure and unsupported binding substance (II) chosen from gamma-cyclodextrin, anionic poly-gamma-cyclodextrin, (2-hydroxypropyl) -gamma-cyclodextrin, gamma-cyclodextrin -phosphate sodium salt, succinylated gamma-cyclodextrin, octabis(2,3,6-tri-O -acetyl)-gamma-cyclodextrin and carboxymethyl -gamma-cyclodextrin, thus selectively binding one of the enantiomers to (II); and (h) sepg. (II) from the liq. mixt.. The enantiomers are soluble in the liq. mixt. to at least 1.0 mM and the solvent is chosen from alkanes, halogenated alkanes, alkenes, alcohols, ketones, nitriles, ethers, and/or esters and in chosen so that (II) is substantially insol. in the liq. mixt.
Patent DK-0765818-T3 (DK)
Inventor: BUTTERWORTH SAUL JAMES
IPC: C09J7/35
Filed: 1996-09-24
Granted: 2005-04-04
Abstract: Hermetically sealed packages for food, cigarettes and the like are formed from packaging material (37) having a tear tape (33) attached thereto. The tear tape includes a surface formed of a material (7) which flows under the conditions needed to seal portions (8,9) of the packaging material together when closing the package so as to fill any gaps between the tape and the packaging material portions. <IMAGE>
Patent DK-0842341-T3 (DK)
Inventor: COX RICHARD DAWSON
IPC: B65D88/12
Filed: 1996-08-01
Granted: 2002-05-06
Abstract: This invention relates to a collapsible frame device (10) for and a method of packing vehicles (11, 12) in a transport container (13). The frame device (10) comprises a base (14) and a first vehicle support means associated with the base for supporting a first vehicle (11) in an inclined raised position relative to the base (14). The first vehicle support means comprising a lower vehicle support member (15) and an upper vehicle support member (16), the support members in use in the erected configuration of the device (10) being horizontally and vertically spaced from each other. The lower (15) and upper (16) vehicle support members are collapsible onto the base (14) to be located substantially flat onto the base in the collapsed configuration of the device.
Patent DK-0799436-T3 (DK)
Inventor: MAASS UWE
IPC: G03B21/00
Filed: 1996-08-31
Granted: 1999-09-06
Abstract: PCT No. PCT/EP96/03832 Sec. 371 Date Jul. 7, 1997 Sec. 102(e) Date Jul. 7, 1997 PCT Filed Aug. 31, 1996 PCT Pub. No. WO97/11405 PCT Pub. Date Mar. 27, 1997An article such as for example a motor vehicle at a publicity function is to be represented in front of different viewers (38) in the background of a stage (28) in the form of a virtual image (26). A presenter (40) is to stand in the image and give explanations. Disposed above the stage (28) is an image source (12, 14). It projects an image, a film, on to a reflecting surface (18) on the floor (30) of the stage (28). Behind that reflecting surface (18) a transparent smooth foil (20) extends at 45 DEG  from the ceiling (32) to the floor (30). The image produced by the image source (12, 14) appears to the viewers (38) as a virtual image (26) behind the foil (20). The presenter (40) stands behind the foil (20) and in the middle of the image.
Patent DK-0869774-T3 (DK)
Inventor: GUSTAFSSON NILS-OVE
IPC: A61K9/50
Filed: 1996-09-03
Granted: 2003-03-24
Abstract: A method of preparing parenterally administrable sustained release microparticles, which comprises preparing core particles in an aqueous medium that is essentially free from organic solvent, a biologically active substance being entrapped therein during or after said preparation, drying the core particles and coating the same with a release-controlling polymer by air suspension technique so as to create a shell on the core particles without any detrimental exposure of the active substance to organic solvent.  Microparticles obtainable by such a method.
Patent DK-0927802-T3 (DK)
Inventor: CHEN WATERSON
IPC: E05B19/00
Filed: 1997-12-29
Granted: 2004-04-19
Abstract: The coded key (90) of a lock apparatus has a head portion (91) and a shank portion (92) which has a cross-section in the form of a circular sector with first and second planar surfaces (93, 94) that extend along the length of the shank portion (92), and a curved surface (95) that interconnects the first and second planar surfaces (93, 94) and that has an arc length greater than 180 DEG . The shank portion (92) is formed with a plurality of key bit projections and key bit grooves on one of the first and second planar surfaces (93, 94). The key bit projections and the key bit grooves have inclined actuating surfaces (921) that form different angles to set the code of the key (90). The angles are in a range from 0 DEG  to about 180 DEG . <IMAGE>
Patent DK-0937270-T3 (DK)
Inventor: CHERON PHILIPPE
IPC: G02B6/44
Filed: 1997-11-04
Granted: 2004-12-27
Abstract: The telecommunications cable of the invention comprises optical fibers and stabilization fibers disposed in an envelope in such a manner as to ensure longitudinal coupling therewith, such that part of the force to which the cable is subjected is shared uniformly over the fibers.
Patent DK-0903017-T3 (DK)
Inventor: GROB MATTHEW S
IPC: H04B7/005
Filed: 1997-06-06
Granted: 2008-01-28
Abstract: In a dispatch system, power of the forward link broadcast channel transmitted from a base station is controlled such that the power level is the minimum necessary and such that transmission of the forward link broadcast channel is terminated if no remote unit is located within the coverage area of the base station. In addition to transmitting a forward link broadcast signal, the base station monitors an access channel. A first remote unit in the base station coverage area receives and decodes the forward link broadcast signal. The first remote unit determines a signal quality of said forward link broadcast signal. If the signal quality is unacceptable, the remote unit transmits a power request access message. The base station responds to the request by increasing the transmission power of forward link broadcast channel. If no requests are received at the base station, the forward link broadcast channel is slowly decreased to a minimum. Transmission of the forward link broadcast channel may be terminated completely.
Patent DK-0932689-T3 (DK)
Inventor: CAMPBELL ROBERT STEWART
IPC: G01N33/68
Filed: 1997-08-23
Granted: 2002-06-17
Abstract: The present invention relates to an assay for determining homocysteine, cysteine, O-acetyl-L-serine and/or methionine levels in a biological sample using an enzyme that catalyzes the degradation of homocysteine, cysteine, O-acetyl-L-serine and methionine. The enzyme being more particularly homocysteine desulphurase, a polynucleotide fragment encoding protozoan homocysteine desulphurase, a recombinant vector comprising a polynucleotide fragment, transformed cells, the protozoan homocysteine desulphurase polypeptide, and pharmaceutical compositions comprising recombinant homocysteine desulphurase for use in medicine or veterinary medicine.
Patent DK-0867179-T3 (DK)
Inventor: MILMAN ISAAC
IPC: A61K31/216
Filed: 1993-12-24
Granted: 2000-11-06
Abstract: A composition which comprises a pharmaceutically acceptable carrier and an active ingredient, such active ingredient comprising L-DOPA ethyl ester in an amount which is at least 97%, by weight, of the active ingredient, and L-DOPA in an amount which is less than 1% by weight of such active ingredient is provided by this invention. This invention also provides a process for preparing such a composition. Further, this invention provides a method of treating a patient suffering from Parkinson's disease which comprises administering to a patient a pharmaceutical composition comprising a therapeutically effective amount of L-DOPA ethyl ester and a pharmaceutically acceptable carrier.
Patent DK-0948963-T3 (DK)
Inventor: PAGEAT PATRICK
IPC: A61K35/36
Filed: 1998-01-21
Granted: 2003-08-11
Abstract: A composition comprising a mixture of fatty acids such as linoleic, oleic and palmitic acids or derivatives thereof derived from secretions of mammalian mammary glands. This composition can be utilized to decrease stress, anxiety and aggressiveness in mammals.
Patent DK-0915013-T3 (DK)
Inventor: BRODART CHRISTIAN ANDRE LUC
IPC: B65D77/22
Filed: 1998-11-06
Granted: 2006-05-01
Abstract: To seal a container, with its contents, a continuous film of at least two layers (1,2) is used, with perforations (3) in the inner film in a density of 100-10000 perforations/dm<2>, and an adhesive bond (5) between them. The adhesive bond leaves a grid (6,7) of zones free of adhesive, to give at least one longitudinal channel to the film edge after cutting. The film is placed over the filled container (A), and is adhesive (4) bonded all round its edge (C). The sealing adhesive is activated through the outer layer (2) without damage to the inner layer (1), to leave the edge channel after bonding to the container edge and after cutting. The continuous sealing adhesive is applied to the inner layer before perforation. The two layers are assembled together in a material which can be wound in a roll as a feed at the sealing station. The adhesive bond (5) between the layers and the sealing adhesive are activated together, when the film material is placed over the filled container. The sealing adhesive has a lower fusion point than the bonding adhesive, and the two adhesives are of different types, where the bonding adhesive is produced by condensation and the sealing adhesive by polymerization. A sealing adhesive is applied to at least one of the layers at the intersections of at least one of the open channels (6,7) at a temperature over ambient levels, but below a temperature where the container contents are heated. The perforated layer can be formed by at least two inner layers, bonded together, where the innermost gives a secure bond with the edge of the container and its covering layer gives a firm bond with the outer layer through the bonding adhesive. The perforations (3) can be in a density of 200-2000 perforations/dm<2> or 500-1200 perforations/dm<2>, equidistant or at different intervals on both plan axes. The open channels have a width of 2-5 mm or 3.0-3.5 mm, in a channel density of 5-15 per dm. Some legs of at least one channel (6,7) carry sealing adhesive (4).
Patent DK-0979235-T3 (DK)
Inventor: BOON-FALLEUR THIERRY
IPC: C12N15/12
Filed: 1998-04-24
Granted: 2006-04-10
Abstract: The invention relates to isolated nucleic acid molecules which code for antigens expressed by tumor cells which maybe recognized by cytotoxic T cells, leading to lysis of the tumor cells which express it. This invention also relates to vectors which are designed to encode the antigen expressed by tumor cells and also to cells transfected by the nucleic acid molecules or vectors which comprise the nucleic acid molecules. Various therapeutic and diagnostic uses arising out of the properties of the nucleic acid molecules and the antigens for which these code are also part of this invention.
Patent DK-0984758-T3 (DK)
Inventor: GUSTAFSSON ANDERS
IPC: A61F13/472
Filed: 1998-05-13
Granted: 2002-06-10
Abstract: An absorbent article with an absorbent body enclosed between inner and outer casing sheets and a stiffening element extending from the rear, through the intermediate, and into the front part of the article. The stiffening element's front and rear parts are broader than its intermediate part and the stiffening element is not wider than 4 cm at its front to intermediate transition region. Side flaps are formed by at least some parts of the remainder of the article which extend laterally beyond the stiffening element, so that the distance between side-edges of the stiffening element and an edge of the side flap varies within the region. The stretch resistance of the side flaps is greater than the stiffening element's longitudinal bending resistance, so inward pressing of the side flaps causes the stiffening element to curve longitudinally, to obtain an upwardly concave shape adapted to the shape of a wearer's body.
Patent DK-0978285-T3 (DK)
Inventor: PAPADIMITRIOU APOLLON
IPC: A61K47/40
Filed: 1999-08-02
Granted: 2006-03-27
Abstract: A composition of a hedgehog protein which contains as an additive zinc ions, magnesium ions, calcium ions, sulfate ions, cyclodextrin, a non-ionic detergent and/or an anionic saccharide is especially stable at room temperature.
Patent ES-2228339-T3 (ES)
Title: Procedimiento para poner en funcionamiento un aparato calefactor de poder calorifico con salida de condensado.
Inventor: SCHAEFER ALBRECHT
IPC: F24H8/00
Filed: 2000-05-19
Granted: 2005-04-16
Abstract: Procedimiento para poner en funcionamiento un aparato calefactor de poder calorífico con un quemador (10) alimentado por medio de una mezcla de combustible y aire, una cámara de quemado (12) y una unidad de intercambio de calor (14) en el que el gas de quemado se refrigera al menos en el intervalo inferior de potencia del aparato calefactor por debajo del punto de condensación del vapor de agua, además con un dispositivo de salida del condensado (17) en el que una parte del dispositivo de salida está conformada para el seguro contra la salida indeseada de gas de escape a modo de sifón (28) para el almacenamiento de un líquido obturador, en particular de condensado de gas de escape, y en el que en caso de existir ciertas condiciones de contorno se activa un programa de llenado del sifón, de tal manera que el aparato calefactor de poder calorífico se pone en funcionamiento durante un intervalo de tiempo determinado con una potencia calorífica mínima, en la que se está por debajo del punto decondensación de los gases de escape, de manera que el sifón (28) se llena de condensado de los gases de escape, y el dispositivo de salida se cierra contra la salida de gases de escape, caracterizado porque después del encendido del aparato calefactor se activa el programa de llenado del sifón en caso de que en un tiempo determinado no se haya realizado ningún requerimiento de calor aunque el aparato calefactor haya estado listo para el funcionamiento.