baber/WOPTO huggingface dataset:
Patent EA-201991121-A1 (EA)
Title: АЗОЛАМИДЫ И АЗОЛАМИНЫ В КАЧЕСТВЕ ИНГИБИТОРОВ ИНТЕГРИНОВ αV
IPC: A61P11/00
Filed: 2017-11-07
Abstract: В настоящем изобретении предусматриваются соединения формулы (I)или их стереоизомеры, таутомеры или фармацевтически приемлемые соли или сольваты, причём все эти переменные имеют значение по определению в настоящей заявке. Эти соединения являются ингибиторами αV-содержащих интегринов. Настоящее изобретение также относится к фармацевтическим композициям, содержащим эти соединения, и к способам лечения заболевания, расстройства или патологического состояния, ассоциированного с дисрегуляцией αV-содержащих интегринов, такого как патологический фиброз, отторжение трансплантата, раковое заболевание, остеопороз и воспалительные расстройства, с применением этих соединений и фармацевтических композиций.
Patent EA-202090634-A1 (EA)
Title: Антагонисты tim-3 для лечения и диагностики онкологических заболеваний
IPC: G01N33/574
Filed: 2018-08-28
Abstract: В настоящем документе предлагаются способы лечения субъекта, страдающего раком, включающие введение субъекту агониста TIM3 (например, анти-TIM3 антитела), одного или в сочетании с другим ингибитором иммунных контрольных точек (например, антагонистом PD-1), где субъект идентифицирован как имеющий высокую частоту TIM3-позитивных клеток (например, в инфильтрирующих опухоль воспалительных клетках) или растворимых TIM3 в периферической крови. Также предоставлены способы оценки эффективности лечения, включающего антагонист TIM3, у субъекта, страдающего раком, включающие измерение частоты TIM3 (и необязательно PD-1) позитивных клеток в определенных популяциях клеток и/или растворимого TIM3 в периферической крови субъекта, где высокая частота TIM3 (и необязательно PD-1) позитивных клеток и/или титр растворимого TIM3 в периферической крови субъекта указывает на ответную реакцию на лечение.
Patent EA-202092763-A1 (EA)
Title: Применение бисамидного производного малоновой кислоты для лечения аллергических и других заболеваний человека и животных
IPC: A61K31/4178
Filed: 2019-05-22
Abstract: Изобретение касается терапии заболеваний, связанных с активностью гистаминовых рецепторов, в частности для терапии аллергических заболеваний, предпочтительно терапии круглогодичного и персистирующего аллергического ринита, зуда, а также ряда других заболеваний, связанных с активностью гистаминовых рецепторов третьего и/или четвертого типа посредством применения соединения N,N'-бис(2-(1H-имидазол-5-ил)этил)малонамидаДанное соединение, а также его фармацевтически приемлемые соли, гидраты, сольваты являются антагонистом гистаминовых рецепторов третьего и/или четвертого типа. Данное изобретение также относится к фармацевтическим композициям, содержащим терапевтически эффективное количество соединения (I).
Patent EA-202190308-A1 (EA)
Title: Применение пролекарств рилузола для лечения болезни альцгеймера
IPC: C07D277/82
Filed: 2019-07-20
Abstract: Раскрываются способы лечения болезни Альцгеймера путем введения пациенту, нуждающемуся в этом, пролекарства рилузола, такого как трорилузол. Также раскрываются фармацевтические композиции и наборы, включающие в себя пролекарства рилузола.
Patent EA-202190428-A1 (EA)
Title: Антагонисты интегрина
IPC: C07D471/04
Filed: 2019-08-19
Abstract: Настоящее изобретение относится к новым антагонистам интегрина формулы (I) и их применению в качестве лекарственного средства, в частности для ингибирования неоваскуляризации.
Patent EA-202191342-A1 (EA)
Title: Модуляторы экспрессии irf5
IPC: C12N15/113
Filed: 2019-11-15
Abstract: В настоящих вариантах осуществления предложены способы, соединения и композиции, используемые для ингибирования экспрессии IRF5, которые можно использовать для лечения, профилактики или облегчения заболевания, связанного с IRF5.
Patent ES-2179727-A1 (ES)
Title: Preparation of nitro aromatic oxidized derivatives involves treatment with nucleophilic reagents for electrochemical oxidation
Inventor: GALLARDO GARCIA ILUMINADA
IPC: C25B3/23
Filed: 2000-03-01
Abstract: The preparation of nitro-aromatic oxidized derivatives involves functionalization of nitro-aromatic derivatives by nucleophilic reagents, through formation of the corresponding Meisenheimer complexes. These then undergo electrochemical oxidation.
Patent ES-2166700-A1 (ES)
Title: Collapsible box
Inventor: LEEBEEK
IPC: B65D19/06
Filed: 2000-03-09
Abstract: A collapsible hinged box 10 comprises a base pallet 12 having a base panel 13, a composite side wall enclosure 18 and a lid 28. The composite side wall enclosure includes four side walls formed from major opposed side wall panels 20 and minor opposed side wall panel pairs 22,24 which are joined by means of plastics hinge formations 26,27 which enable the side wall panels to be folded into a slack between the lid 28 and the base 13 when the box is in a collapsed position. An array of drop-away base clips 32 are hingedly connected to the base by means of clip retaining plates and drop-away lid clips 34 are hingedly connected to the lid in the same fashion by formations 36. The base and lid clips are arranged to connect the respective base 13 and lid 28 to the composite side wall enclosure in its erected condition, and are also adapted to sandwich the stacked side wall panels between the base and the lid by clamping the base and the lid together.
Patent ES-2171361-A1 (ES)
Title: System for exercising the lower extremities in seated persons
Inventor: GALVEZ CAMPOS JOSE LUIS
IPC: A61H1/02
Filed: 2001-02-27
Abstract: The system is particularly suitable for persons who must remain in seated position over long periods, for instance, persons working in offices and the like. The system comprises one or two support surfaces (2) for the feet of the user, which are moved by a motor-driven base (1). Said support surfaces (2) may perform an alternating longitudinal movement, a lifting and lowering movement or a movement combining the latter two. The support surfaces (2) are moved, for example, by means of connecting rods (5) hingedly connected to said support surfaces (2) in the central point (6) and hingedly connected by their other end to eccentric pivots (9) allocated to respective toothed wheels (7) which are mounted with rotational freedom on their respective axis (8), an intermediate motor-driven pinion (10) that conveys rotational movements in opposite direction to the wheels (7) being placed between said wheels. The support surface can be embodied as a bar that is transversal relative to the motor-driven base (1), which is preferably used in collective transport vehicles such as motor coaches, airplanes, etc.
Patent ES-2187280-A1 (ES)
Title: Printed circuit board with isolated metallic substrate comprising an integrated cooling system
Inventor: BORREGO BEL CARLOS
IPC: H05K7/20
Filed: 2001-06-28
Abstract: A board has a metallic substrate (10), an electrically-isolating layer (11), which is stuck to the metallic substrate (10), and electroconductive tracks (12) which interconnect electronic power components (24) and which are stuck to the electrically-isolating layer (11). The metallic substrate (10) has heat transfer channels which incorporate conduits for a coolant, the conduits extending to the outside of the metallic substrate as far as an area for transferring heat to an external medium.
Patent ES-2197008-A1 (ES)
Title: Intrauterine insemination catheter
Inventor: MENA GERICO JUAN JOSE
IPC: A61D19/02
Filed: 2002-06-03
Abstract: Catheter for intrauterine insemination, which is useful in artificial insemination in different animal species and, thus, it is preferably useful for intrauterine insemination of pigs. The catheter (1) for intrauterine insemination is defined by a unitary element comprised of an elongated tube-shaped body (2) provided in one of its ends, the end to be introduced in the reproductive system of the animal, with a rounded surface body (3) provided with a hole (4) as an extension of the axial hole (5) of the tube-shaped body (2).
Patent ES-2211310-A1 (ES)
Title: Sweet is composed of external covering of chocolate and of filling of 84.43 per cent fondant
Inventor: GIL CLEMENTE MANUEL
IPC: A23G3/00
Filed: 2002-10-14
Abstract: The sweet is composed of an external covering of chocolate and of a filling of 84.43 per cent fondant. Over the fondant is an especially white covering of 11.36 per cent. Other constituents are liqueur 3.93 per cent, enzymes 0.18 per cent, aroma 0.09 per cent, coloring agent 0.01 per cent.
Patent ES-2334738-A1 (ES)
Title: Device for detecting a zero-crossing of an electric alternating current
Inventor: MORET CODINA MARIA CRISTINA
IPC: G01R19/175
Filed: 2008-02-20
Abstract: Device for regulating the electric feeding of a charge (1) through the alternating current, with at least some serially opposed switching elements (3) or a switching network, and a unit for controlling (2) said switching elements (3). The device comprises a comparator (5) of the saturation voltage "V CEsat " of the switching elements (3), associated to an attenuation network (8) in an input terminal, insofar as in the other input terminal there is a voltage generator having the reference "V ref " disposed between the collector and emitter "V ce " corresponding to an "I ce " current equal to zero, in order to determine the moment of null circulation and current due to said switching elements (3) through the fall of "V CEsat " below "V ref ", determining a current zero-crossing signal to the control unit (2).
Patent ES-2343668-A1 (ES)
Title: Procedure for marking, encryption, labelling and optical coding
Inventor: BARRANCO QUERO ANGEL
IPC: B23K26/06
Filed: 2009-02-04
Abstract: It permits marking or recording motifs (301) on surfaces whereon there has been deposited previously a fluorescent polymer layer (300) through a procedure of plasma polymerisation (100) of molecules of a colourant. The procedure combines the special characteristics of the polymer layers making them suitable for being capable of recording diverse motifs (301) thereon, and the possibility of recording by laser (101) or other techniques. Among such characteristics should be mentioned the possibility of a notable visual effect, including for thicknesses of 100 nm, the use of layers non-observable when illuminated with visible light, the high optical quality (transparency) thereof, or the facility wherewith they may be processed by subsequent treatments, including diverse laser treatments (101).
Patent ES-2410261-A1 (ES)
Title: Method and device for the recycling and exploitation of biodegradable domestic waste produced in the dwellings of a community, by means of biogas-production plants, in order to produce electricity and fertilizer and to heat water
Inventor: NUNEZ JARAMILLO ANTONIO
IPC: C02F3/28
Filed: 2009-03-06
Abstract: The invention relates to a method and device for the recycling and exploitation of biodegradable domestic waste produced in the dwellings of a community, by means of prefabricated biogas-production plants, in order to produce electricity and fertilizer and to heat water. The waste is ground in a grinder provided in the kitchen sinks and is conveyed, by means of a network separate from the sewage network, to a biogas-production plant formed by digesters, where biogas is produced by means of anaerobic digestion. The invention includes safety and control mechanisms, a biogas consumer, a biogas reservoir and a place where the inert material resulting from biodigestion can be deposited. This material can be used as fertilizer. Optionally, the waste can originate from gardens. The biogas is consumed in the consumer and used to produce electrical power, mechanical power or to heat water. The electrical power generated may be fed into the grid.
Patent ES-2362774-A1 (ES)
Title: Bathing gel with improved environmental profile
Inventor: LOPEZ SALVANS MARTA QUERALT
IPC: A61Q19/10
Filed: 2009-12-28
Abstract: Compositions adapted for use as a bathing (shower or bath) gel for personal cleansing are provided, the compositions containing reduced loadings of relatively harsh anionic surfactants and of fragrance oils, but retaining a spectrum of functional properties perceived by consumers as desirable. The compositions include lower concentrations of anionic surfactants compared to standard bathing gel compositions, but the addition of quantities of a long-chain alkyl, hydroxyalkyl cellulose derivative to the composition preserves or enhances functional properties such as viscosity, skin mildness, foam generation on lathering, subjective perceived cleansing appreciation, and fragrance performance. The bathing gels provide an environmental benefit such as reduced surfactant loading, biodegradability, and aquatic toxicity of wastewater streams when used in the place of standard bathing gels.
Patent ES-2380474-A1 (ES)
Title: Anchoring for a motorcyclist protection system
Inventor: GONZALEZ URIARTE JUAN JOSE MARIA
IPC: E01F15/04
Filed: 2010-10-15
Abstract: The present invention relates to an anchoring (1) for a motorcyclist protection system, comprising a flat bar having three substantially straight sections (T1, T2, T3) and two bends made in the same direction, the first bend defining a first inner angle 1 between the first (T1) and the second (T2) section and the second bend defining a second inner angle 2 between the second (T2) and the third (T3) section, a first section (T1) being intended to be fixed to a post (6) of a vehicle restraint system, the third section (T3) being intended to be coupled with a motorcyclist protection barrier (9), wherein the planes containing the first (T1) and the third section (T3) form an angle +- of 20 DEG +- 5 DEG and the sum of the inner angles 1 and 2 is 200 DEG +- 5 DEG
Patent JO-P20190230-A1 (JO)
Title: Processes for preparing jak inhibitors and related intermediate compounds
Inventor: LIN QIYAN
Filed: 2009-01-15
Abstract: The present invention is related to processes for preparing chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines of Formula III, and related synthetic intermediate compounds. The chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines are useful as inhibitors of the Janus Kinase family of protein tyrosine kinases (JAKs) for treatment of inflammatory diseases, myeloproliferative disorders, and other diseases.
Patent SG-126722-A1 (SG)
Title: Tray for electronic components
Inventor: ONO HIROKAZU
IPC: B65G49/00
Filed: 2003-05-21
Abstract: A carrier for transporting electronic components is provided for enhancing the reliability in parts transportation by preventing an electronic components from being damaged during the transportation. A tray for electronic components having a plurality of accommodation cavities for accommodating electronic components therein, said accommodation cavities being defined by surrounding partition walls and arranged in a grid iron form characterized in that said tray is formed with support steps in said surrounding partition walls within said cavities to receive an edge portion of an electronic component board, said support step in each cavity continuing into a contact accommodation space for accommodating a group of contacts formed on the electronic component board, said contact accommodating space having descending walls to surround and define the same, each descending wall having an inclination with respect to a vertical plane, said inclination being larger than required for an easy mold removing operation during an injection molding.
Patent SG-101083-A1 (SG)
Title: Lipoteichoic acid from latic acid bacteria and its use to modulate immune responses mediated by gram-negative bacteria, potential pathogenic gram-positive bacteria
Inventor: VIDAL KARINE
IPC: A61K31/739
Filed: 2002-04-23
Abstract: The invention relates to a composition for modulating the immune responses induced by Gram negative bacteria, potential pathogenic Gram positive bacteria and/or their derivatives, comprising lipoteichoic acid from lactic acid bacteria as an active ingredient. It also relates to the use of a lipoteichoic acid from lactic acid bacteria as an active ingredient and/or lactic acid bacteria producing it and/or its supernatant of culture, in the manufacture of a medicament, an oral or topical product for cosmetic, dermatological or ophthalmological applications, a food or petfood composition for modulating bacterial colonisation, immune responses and decreasing the inflammatory processes associated with bacterially-mediated disease and infection in the gastrointestinal tract, bone, skin, eye, ear, lung and oral cavity. The invention also relates to lipoteichoic acid selected thereof.
Patent SG-126048-A1 (SG)
Title: Systems and methods for managing out-of-band device connection
Inventor: PIRZADA FAHD B
IPC: H04W12/06
Filed: 2006-03-08
Abstract: Systems and methods for managing connection of devices to a wireless network using out-of-band communications.
Patent TR-202010729-A1 (TR)
Inventor: ABDULLAH TAŞKIN
IPC: A61K31/4545
Filed: 2020-07-07
Abstract: Mevcut buluş; apiksaban ve en az bir bağlayıcı içeren bir tablet ile ilgili olup, burada apiksaban ve en az bir bağlayıcı, bir çözücü içinde çözünmektedir. Mevcut buluş ayrıca, basit, hızlı, uygun maliyetli, zaman tasarrufu sağlayan ve endüstriyel olarak uygun bir prosesle de ilgilidir.
Patent TR-202014462-A1 (TR)
Title: Otobüsler i̇çi̇n açik kapak uyari si̇stemi̇
Inventor: EMRAH DUTKUN
IPC: E05B79/10
Filed: 2020-09-11
Abstract: Buluş, otobüslerde, aracın (1) yanlarında bulunan kapaklar (2) ile ilgili olup, özelliği; otobüslerde, aracın (1) yanlarında bulunan kapakların (2) veya kapaklardan (2) birinin açık olduğunda uyarı verilmesini sağlayan otobüsler için açık kapak (2) uyarı sistemi oluşturmak üzere, araç (1) karoserisine yerleştirilen sensörler (3), sensörünün (3) önünü kesecek şekilde tasarlanan bir bagaj parçası, kesici parça (4) ile birlikte veya algılama elemanlarıyla kapağın (2) açık olup olmadığının araç (1) tarafından algılanmasını sağlayan en az bir kontrol ünitesi içermesi ile karakterize edilir.
Patent AR-022947-A1 (AR)
Title: UN PRODUCTO DE CELULOSA MODIFICADO, UN MÉTODO PARA SU PREPARACIoN Y UN LODO DE PERFORACIoN QUE LO COMPRENDE.
IPC: C08L5/00
Filed: 2000-03-16
Abstract: Producto de celulosa modificado con AL, Fe (II), Fe(III), Zn, Ni, Sn (II) y Sn(IV), método para su preparacion y lodo de perforacion que lo comprende. Unproducto de celulosa modificado que comprende éter de celulosa, tal como carboximetil celulosa,h idroxietil celulosa, carboximetil hidroxietil celulosa, metilcelulosa, hidroxietil metil celulosa, o un producto de goma de xantano, caracterizado porque contiene además sales de cationes de aluminio, ferro-ferri-, zinc,níquel, estano (2), yestano ( 4), y ácido nitrilotriacético, ácido 1,2-ciclo-hexan-di-amin-N,N,N, N-tetraacético, ácido di-etilen-tri-amino-pente-acético,ácido etilen-di-oxi-bis(etilen-nitrilo)-tetraacético, ácido (N-(2-hidroxi-etil)-etilen-diamin-N,N,N, triacético;ácido trietil en-tetra-amino-hexa acético oácido N-(hidroxietil) etilen-diamino-triacético como ligando. Particulamente el producto puede ser utilizado como un aditivo para lodo de perforacion. Unmétodo de preparacion del producto de celulosadescripto que compren de hacer reaccionar un compuesto de celulosa con sales de cationes de Al. Fe (II), Fe(III),Zn, Ni, Sn (II) y Sn(IV) con dervaciones de ácido acético como los descriptos como ligando. Un lodo de perforacion que contiene unproducto de celulosa como el descripto. Aditivos para fluidos de perforacion, terminacion y reacondicionamiento en la perforacion de pozos subterráneos de petroleo, gas y agua.
Patent AR-029403-A1 (AR)
Title: Derivados n-sustituidos de carbamoiloxialquil-azolio,un proceso para su fabricacion, composicion farmaceutica y el uso de los mismos para la preparacion de un medicamento
IPC: C07D417/14
Filed: 2000-10-31
Abstract: Derivados N-sustituido de carbamoiloxialquil-azolio de la formula general (1), en donde Q, Y, Ra, R?, Rl, Y y X- son segun lo definido en la memoria descriptiva como así también sus sales, hidratos o solvatos. Los compuestos tienen actividad antifungal y son utiles para el tratamiento de enfermedades fungales. Además, se describe un proceso para su fabricacion, composiciones farmacéuticas que comprenden dichos derivados y el uso de los mismos para la preparacion de un medicamento.
Patent AR-028300-A1 (AR)
Title: Caravana con testigo de seguridad para identificacion animal
IPC: A01K11/00
Filed: 2000-12-26
Abstract: Dispositivo identificador de animales que permite realizar una correcta y eficiente trazabilidad, estando constituido por un cuerpo laminar que posee una línea de troquel o corte a fin de permitir el desprendimiento de una porcion de superficie del mismo, generándose por dicho corte un primer cuerpo denominado testigo de seguridad y un segundo cuerpo denominado campo principal, preferentemente dicho cuerpo laminar estará conformado a partir de dos cuerpos laminares, cuerpo base y cuerpo transparente respectivamente, adheridos entre sí formando un solo cuerpo laminar, testigo y cuerpo principal unidos por la línea de troquel, ambas porciones testigo y principal tienen impresa y troquelada igual informacion en ambos planos laminares, preferentemente un mismo codigo de barras en cada una de ellas, permitiendo en su desprendimiento por la línea de troquel, obtener igual informacion impresa, incluida y/o troquelada en ambas porciones laminares independientes, uno de los cuerpos, el principal dispone sobre el extremo superior opuesto al corte troquelado una prolongacion en forma de manguito cilíndrico que remata en un cono convexo que coopera con un collar circular concavo, manguito que permitirá bloquear la caravana una vez ubicada en la oreja del animal, entre los dos cuerpos laminares se ubicarán un sello de seguridad, un material absorbente a fin de conservar muestra de sangre y toda informacion atinente a la identificacion del animal, en dicho cuerpo testigo se ubicará una perforacion capaz de alojar a un precinto con cierre de seguridad a los efectos de conformar una ristra de testigos para su ulterior archivo.
Patent AR-027708-A1 (AR)
Title: Uso de nitrilos cationicos que contienen compuestos blanqueadores que reducen el manchado en la plata.
IPC: C11D1/62
Filed: 2001-03-23
Abstract: Se trataq de formulaciones detergentes que contienen nitrilos cationicos que muestran una reduccion de manchado en la plata en comparacion conformulaciones similares que contienen TAED.
Patent AR-032226-A1 (AR)
Title: Dispositivo de control para maquina cosechadora
Inventor: DEERE COMPANY
IPC: A01D41/127
Filed: 2002-01-08
Abstract: Un dispositivo de control para una máquina cosechadora que comprende al menos un sensor que está disenado para generar una senal que contiene informacion sobre los ruidos provocados por el material de cultivo cosechado a medida que pasa a través de un conjunto procesador de cultivo. El sensor está espaciado y hacia afuera del flujo de material de cultivo cosechado que pasa a través del conjunto procesador de cultivo.
Patent AR-033049-A1 (AR)
Title: Composiciones de mezclas fitofarmaceuticas
IPC: A01N25/14
Filed: 2002-03-18
Abstract: Se proveen composiciones para la preparacion de productos herbicidas en forma de polvo humectable y suspension en polvo que contienen agentes agroquímicos de bajo punto de fusion, tales como ésteres de bromoxinilo. Las composiciones preferidas son sustancias fundidas en conjunto de ésteres de bromoxinilo con al menos un herbicida o pesticida adicional, particularmente atrazina. Las composiciones de la invencion tienen puntos de fusion más elevados que el componente de éster de bromoxinilo, y por lo tanto, tienen ventajas en el sentido que el uso de disolventes y/o portadores en las formulaciones puede evitarse o minimizarse. Las composiciones pueden ser procesadas en polvos secos sin los problemas asociados con el ablandamiento o fusion de ésteres de bromoxinilo puros durante la trituracion o molienda, y sin la necesidad de dilucion del producto con cantidades sustanciales de portadores inactivos. Las composiciones que contienen las mezclas no pierden selectividad en presencia de adyuvantes oleosos.