baber/WOPTO huggingface dataset:
Patent WO-2019182963-A1 (WO)
Inventor: DELCOURT EMILE
IPC: G06F21/31
Filed: 2019-03-18
Abstract: Among other things, this document describes systems, methods, and apparatus for monitoring and protecting a user credential issued by an organization when that credential is used outside that organization's network security perimeter. For example, a reverse proxy server (RPS) receives a client request directed to a content provider's site. The RPS initiates a process that involves parsing the request message and extracting a user credential. The RPS locates a credential policy from the credential owner based on the user credential. The RPS can issue an API request to a credential service that is authoritative for the credential. That credential service may return a directive to the RPS specifying how to handle the client request message. Preferably, the operation is transparent to the content provider whose site was the target of the client's request message. Activity records can be presented in visualizations that enhance security analysts' tactical comprehension at a glance.
Patent WO-2019183570-A1 (WO)
Inventor: GARCIA-BLANCO MARIANO
IPC: C07H21/04
Filed: 2019-03-22
Abstract: The present invention includes compositions and methods for treating an autoimmune disorder or a cancer in a subject in need thereof, the method comprising: administering an effective amount of a composition comprising an oligonucleotide that specifically binds a complementary sequence of the Interleukin-7 receptor (IL7R) pre-mRNA that influences splicing of exon 6, wherein the SM-ASO increases or decreases inclusion of exon 6 in IL7R pre-mRNAs and respectively decreases or increases expression of the soluble isoform of IL7R (sIL7R). In certain embodiments, the oligonucleotide is an antisense oligonucleotide (ASO), or a splice- modulating antisense oligonucleotide (SM-ASO).
Patent WO-2019212935-A1 (WO)
Title: Methods of monitoring, treating, and preventing renal inflammation associated with infection
Inventor: BRETON SYLVIE
IPC: A61P13/12
Filed: 2019-04-29
Abstract: The invention provides methods of monitoring development of renal inflammation in a subject who has an infection by analyzing levels of one or more UDP-hexoses, such as UDP- glucose, UDP-galactose, UDP-glucuronic acid, N-acetyl-UDP-glucosamine or N-acetyl-UDP- galactosamine, in a sample from the subject. The invention also provides methods of treating or preventing renal inflammation in a subject who has an infection by providing a P2Y14 receptor antagonist to the subject.
Patent WO-2019217162-A1 (WO)
Title: Computer vision and speech algorithm design service
Inventor: EBSTYNE MICHAEL
IPC: G06V10/774
Filed: 2019-05-01
Abstract: A synthetic world interface may be used to model digital environments, sensors, and motions for the evaluation, development, and improvement of computer vision and speech algorithms. A synthetic data cloud service with a library of sensor primitives, motion generators, and environments with procedural and game-like capabilities, facilitates engineering design for a manufactural solution that has computer vision and speech capabilities. In some embodiments, a sensor platform simulator operates with a motion orchestrator, an environment orchestrator, an experiment generator, and an experiment runner to test various candidate hardware configurations and computer vision and speech algorithms in a virtual environment, advantageously speeding development and reducing cost. Thus, examples disclosed herein may relate to virtual reality (VR) or mixed reality (MR) implementations.
Patent WO-2019240891-A1 (WO)
Inventor: YANG MICHAEL X
IPC: H01L21/027
Filed: 2019-05-03
Abstract: L'invention concerne des procédés de cuisson post-exposition. Dans un exemple, un procédé comprend le placement d'une pièce à travailler munie d'une couche de résine photosensible sur un support de pièce à travailler disposé dans une chambre de traitement. Le procédé comprend l'exposition à travers un photomasque de la résine photosensible à des photons d'une longueur d'onde. Le procédé comprend la réalisation d'un processus de chauffage par cuisson post-exposition sur la pièce à travailler avec la couche de chauffage de résine photosensible. Le procédé de chauffage par cuisson post-exposition peut comprendre le chauffage de la pièce à travailler tant avec une source de chaleur rayonnante qu'avec une seconde source de chaleur disposée dans le support de pièce à travailler jusqu'à ce qu'une température de la pièce atteigne un point de consigne de température de cuisson post-exposition.
Patent WO-2019217675-A1 (WO)
Title: Noise reducing filled polyester
Inventor: HU ZHAOKANG
IPC: C08L67/02
Filed: 2019-05-09
Abstract: A polyester composition comprising, based on the total weight of the polyester composition, a first polyester and a second polyester, wherein a weight ratio of the first polyester to the second polyester is 80:20 to 20:80, preferably 60:40 to 40:60; 5 to 60 weight percent (wt%), preferably 5 to 50 wt% of a reinforcing filler; and 5 to 60 wt%, preferably 10 to 50 wt%, more preferably 20 to 50 wt% of an inorganic filler having a specific gravity of greater than 3 grams per cubic centimeter, as determined in accordance with ASTM D792, wherein a molded article comprising the polyester composition has a sound transmission loss of greater than 30 dB, preferably 35 to 50 dB, more preferably 36 to 45 dB, as determined at 1,250 Hz according to ASTM E1050 using a molded disc with a diameter of 100 mm and a thickness of 3.2 mm.
Patent WO-2019226518-A1 (WO)
Title: Waterproof and explosion-proof circuit board and electronic valve actuator for flow control applications
Inventor: GORBUTT MICHAEL
IPC: H05K5/06
Filed: 2019-05-20
Abstract: A bulkhead passthrough connector containing a printed circuit board (PCB) for transferring electrical signals across a bulkhead to an electronic valve actuator, an electronic valve actuator configured to operate and communicate with a valve using a PCB through a bulkhead, the electronic valve actuator, and a method of assembling a bulkhead passthrough connector incorporating a PCB. The embodiments may include a passthrough partition which separates one side of the bulkhead from another. A PCB retainer may also be secured to the passthrough partition. The PCB is attached to the PCB retainer and extends from one side to another side of the bulkhead through the passthrough partition. The PCB further includes electrical paths printed on the PCB and electrical connectors located on both sides of the bulkhead to enable communication with external devices.
Patent WO-2019236653-A1 (WO)
Title: System and method for removing phenolic preservations from insulin formulations
Inventor: HONG LIM FRANCIS
IPC: C07K14/62
Filed: 2019-06-05
Abstract: The present invention comprises a method for removing or depleting phenolic preservatives found in insulin formulations in order to prevent inflammation at the site of infusion in a diabetic patient. Particularly, the disclosed embodiments include the separation device, system for removing phenolic preservatives, and separating phenolic preservatives from insulin, and methods of making and using the same. A phenolic preservative separation device comprises: a vessel able to store a liquid insulin formulation comprising a phenolic preservative and an insulin; and, a physical substrate stored within the vessel, the substrate comprising at least one macromolecule able to selectively bind and remove from the liquid about 60-99% of the phenolic preservative within the insulin formulation, wherein the insulin does not bind to, or binds 10% or less to, or about 1-5% to, the physical substrate.
Patent WO-2019241540-A1 (WO)
Title: Indazole containing macrocycles and therapeutic uses thereof
Inventor: KC SUNIL KUMAR
IPC: A61P35/00
Filed: 2019-06-13
Abstract: Indazole macrocycle compounds of formula (I) for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole macrocycle compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states. Formula (I)
Patent WO-2020006036-A1 (WO)
Title: Crispr effector system based amplification methods, systems, and diagnostics
Inventor: ZHANG FENG
IPC: C12Q1/6844
Filed: 2019-06-26
Abstract: Provided herein are methods and systems for amplifying and/or detecting target double-stranded or single-stranded nucleic acids. The methods comprise combining a sample comprising the target nucleic acid with an amplification reaction mixture, amplifying the target nucleic acid, and further amplifying the target nucleic acid by repeated opening, unwinding, annealing and extension under isothermal conditions. The amplification reaction mixture may include an amplification CRISPR system, a helicase, a primer pair, and a polymerase. The amplification CRISPR system may comprise a first and second CRISPR/Cas complex, the first and second CRISPR/Cas complex may comprise a first CRISPR/Cas enzyme and a first guide molecule that guides the first CRISPR/Cas complex to a first strand of the target nucleic acid; the second CRISPR/Cas complex may comprise a second CRISPR/Cas enzyme and a second guide molecule that guides the second CRISPR/Cas complex to a second strand of the target nucleic acid.
Patent WO-2021015708-A1 (WO)
Title: Image data mapping
Inventor: MARSA JOAN SOLANS
IPC: H04N1/60
Filed: 2019-07-19
Abstract: Image data mapping is described in which a patch image with patch image parameters including a patch image identifier relating to the patch image is generated; the production of the patch image on a recorded medium in a first printing environment is initiated; the produced patch image with the patch image parameters to determine patch image data of the produced patch image is analysed; and the patch image data is mapped to the patch image identifier to generate an information resource.
Patent WO-2020023493-A1 (WO)
Title: Methods and composition for targeted genomic analysis
Inventor: RAYMOND CHRISTOPHER
IPC: C12N15/09
Filed: 2019-07-23
Abstract: The disclosure provides methods and reagents for preparing DNA libraries from biological materials for targeted sequencing. The approach can enhance the efficiency and sensitivity of targeted sequencing applications, such as liquid biopsy analyses to assess genetically driven conditions. In an embodiment, the disclosed method comprises attaching the 5' end of an oligonucleotide adapter to the 3' end of double-stranded DNA fragment to produce an adapter/ fragment chimeric molecule; producing at least one complementary strand of the adapter/fragment chimeric molecule by linear amplification; hybridizing the at least one complementary strand with an oligonucleotide probe, wherein the oligonucleotide probe comprises a hybridization domain with a sequence that hybridizes to a target sequence in the complement strand to produce a targeted complement strand/probe duplex; purifying the targeted complement strand/probe duplex; and extending the probe in the purified targeted complement strand/probe duplex and amplifying with PCR to produce a plurality of sequencing template molecules.
Patent WO-2020028695-A1 (WO)
Title: Percutaneous vascular anastomosis
Inventor: HENNEMEYER CHARLES
IPC: A61F2/07
Filed: 2019-08-01
Abstract: Collapsible branched anastomosis devices allow for the formation of percutaneous vascular anastomoses using a Seldinger wire technique. This minimally invasive approach eliminates the need for a large surgical incision and also avoids the use of time consuming hand-suturing. The devices collapse to a fraction of their expanded volume and are configured to fit within a delivery sheath for over the wire delivery through a small incision in a blood vessel.
Patent WO-2020036749-A1 (WO)
Inventor: DI PROIETTO DANIELE
IPC: G06F9/455
Filed: 2019-08-02
Abstract: La présente invention concerne un procédé d'automatisation de virtualisation de fonction de réseau (NFV) à l'aide d'un cadriciel NFV modulaire, lequel procédé consiste à s'abonner, par un module de commande d'un réseau, à une clé d'un dispositif de stockage d'état du réseau. Le dispositif de stockage d'état comprend des objets de données stockés et des clés uniques. Chacun des objets de données stockés est associé à l'une des clés uniques. La clé est l'une des clés uniques. Une notification est reçue au niveau du module de commande à partir du dispositif de stockage d'état. La notification est associée à la clé. Le module de commande lit un objet de données, associé à la clé, à partir des objets de données stockés dans le dispositif de stockage d'état en réponse à la notification, et le module de commande modifie un flux de trafic de réseau du réseau par l'intermédiaire d'au moins deux fonctions de réseau de logiciel du réseau sur la base de l'objet de données.
Patent WO-2020041472-A1 (WO)
Title: Compression bandaging
Inventor: MURPHY THOMAS S
IPC: A61K9/70
Filed: 2019-08-21
Abstract: A compression bandage is provided that includes a zinc oxide composition and/or one or more other therapeutic agents. In use, the bandage can be compression wrapped directly contacting a subject's skin for application of the zinc oxide composition and/or other therapeutic agents.
Patent WO-2020041597-A1 (WO)
Title: Systems and methods for processing gases
Inventor: SOANE DAVID
IPC: C07C2/00
Filed: 2019-08-22
Abstract: The invention includes a gas processing system for transforming a hydrocarbon- containing inflow gas into outflow gas products, where the system includes a gas delivery subsystem, a plasma reaction chamber, and a microwave subsystem, with the gas delivery subsystem in fluid communication with the plasma reaction chamber, so that the gas delivery subsystem directs the hydrocarbon-containing inflow gas into the plasma reaction chamber, and the microwave subsystem directs microwave energy into the plasma reaction chamber to energize the hydrocarbon-containing inflow gas, thereby forming a plasma in the plasma reaction chamber, which plasma effects the transformation of a hydrocarbon in the hydrocarbon-containing inflow gas into the outflow gas products, which comprise acetylene and hydrogen. The invention also includes methods for the use of the gas processing system.
Patent WO-2020055740-A1 (WO)
Title: Implant with elastomeric membrane and methods of fabrication thereof
Inventor: RENKE PETER
IPC: A61F2/12
Filed: 2019-09-09
Abstract: A method of forming an implant includes providing a preformed shell formed from at least one cured elastomeric layer. The shell includes an outer surface, an inner surface, and an opening for accessing an interior volume of the shell. The method further includes expanding the shell to an expanded state, in which the interior volume is greater than the interior volume of the shell at a time of forming the shell and forming an inner zone having at least one inner elastomeric layer on at least a portion of the inner surface of the shell, while the shell is in the expanded state, thereby forming a multi-zone shell. The method further includes reducing the interior volume of the multi-zone shell, thereby contracting the at least one inner elastomeric layer of the inner zone and causing texturing of the at least one inner elastomeric layer.
Patent WO-2020092176-A1 (WO)
Title: Devices and method for removing a shell from a mould
Inventor: MOJDEH MEHDI
IPC: B29C51/26
Filed: 2019-10-25
Abstract: Embodiments relate to automating removal of an untrimmed shell (150) from a mold (140). In one embodiment, a shell removal device includes a body and a platform (120) disposed within the body (110). The platform is configured to secure a mold that has an untrimmed shell formed over the mold. The shell removal device further includes a cover (130A) configured to secure the untrimmed shell to an upper surface of one or more sidewalls of the body and provide a seal between a lower surface of the untrimmed shell and the upper surface of the one or more sidewalls of the body. The shell removal device may include a media inlet (116) in the body (110) to permit pressurized media into the interior (114) of the body to cause a pressure differential between an upper surface of the untrimmed shell and the lower surface of the untrimmed shell to cause the untrimmed shell to release from the mold.
Patent WO-2021086376-A1 (WO)
Inventor: GORBIKOV EVGENY
IPC: G01J5/10
Filed: 2019-10-31
Abstract: Offset print apparatus comprises: a blanket to receive print agent; a non-contact temperature sensor to monitor electromagnetic radiation from a measurement location of the blanket and generate a respective output; and a controller to: receive the output from the non-contact temperature sensor; determine coverage information relating to a print agent coverage of the blanket at the measurement location; and calculate a temperature of the blanket at the measurement location taking into account both the output from the non-contact temperature sensor and the determined coverage information.
Patent WO-2020106786-A1 (WO)
Inventor: POPITZ MICHAEL
IPC: A61F5/56
Filed: 2019-11-20
Abstract: An apparatus for supporting the neck and head of a user for airway management includes a base support section (101) with a sloping ramp (115) for supporting the user's shoulders and back, where the base support section (101) can rest on a resting surface (i.e., a surface (207) on which the apparatus is positioned), a front side, two opposing sides and a back side with the sloping ramp (115) extending from a front edge of the apparatus to a top head-receiving portion. In general, the apparatus can be made in different sizes for accommodating different individuals. In some embodiments, the base support section (115) can have a width in a range of about 20 inches to about 30 inches, a depth in a range of about 16 to about 17 inches and a height in a range of about 12 to about 15 inches, though other sizes can also be employed.
Patent WO-2020131404-A1 (WO)
Inventor: PARRY JONATHAN SCOTT
IPC: G06F21/62
Filed: 2019-12-05
Abstract: A request for memory sub-system log data is received from a host system. In response to receiving the request, a symmetric encryption key for encrypting the requested memory-sub-system log data is generated. The requested memory sub-system log data is encrypted using the symmetric encryption key. The symmetric encryption key is encrypted using an asymmetric encryption key. An encrypted data payload is generated and sent to the host system in response to the request. The encrypted data payload comprises the encrypted encryption key and the encrypted memory sub-system log data.
Patent WO-2020123699-A1 (WO)
Title: Composés et compositions qui provoquent la dégradation de mycn et/ou de cmyc et leurs procédés d'utilisation
Inventor: STOCKWELL BRENT R
IPC: G01N33/50
Filed: 2019-12-11
Abstract: La présente invention concerne, entre autres, des squelettes et des composés possédant la structure (I). L'invention concerne également des compositions contenant un support de qualité pharmaceutique et un ou plusieurs composés selon la présente invention. L'invention concerne en outre des méthodes de traitement ou d'amélioration des effets d'un cancer chez un patient, des procédés qui permettent de détruire sélectivement la cellule cancéreuse, des procédés de modulation de l'activité de signalisation de mTORC1/2 dans la cellule, des procédés de modulation de l'activité d'un régulateur maître de MycN chez le patient porteur d'un neuroblastome avec amplification de MycN (MycNAMP NBL), des méthodes qui permettent, de façon sélective, de traiter ou d'améliorer les effets d'un cancer chez un patient qui en a besoin, ainsi que des plate-formes et des procédés qui permettent d'identifier un composé qui provoque la dégradation d'une protéine liée au cancer. L'invention concerne également des nécessaires qui comportent un composé ou une composition pharmaceutique selon la présente invention. L'invention concerne également des méthodes de traitement de cancers et des procédés de modulation de régulateurs maîtres de MYC à l'aide d'autres composés.
Patent WO-2020197601-A1 (WO)
Title: Systems and methods for forecast alerts with programmable human-machine hybrid ensemble learning
Inventor: JAMMALAMADAKA ARUNA
IPC: G06N7/00
Filed: 2019-12-13
Abstract: A method for computing a human-machine hybrid ensemble prediction includes: receiving an individual forecasting question (IFF); classifying the IFF into one of a plurality of canonical question topics; identifying machine models associated with the canonical question topic; for each of the machine models: receiving, from one of a plurality of human participants: a first task input including a selection of sets of training data; a second task input including selections of portions of the selected sets of training data; and a third task input including model parameters to configure the machine model; training the machine model in accordance with the first, second, and third task inputs; and computing a machine model forecast based on the trained machine model; computing an aggregated forecast from machine model forecasts computed by the machine models; and sending an alert in response to determining that the aggregated forecast satisfies a threshold condition.
Patent WO-2020132050-A1 (WO)
Title: Mixage en mode de multiples points d'émission réception
Inventor: KHOSHNEVISAN MOSTAFA
IPC: H04L5/00
Filed: 2019-12-18
Abstract: Selon divers aspects, la présente invention concerne généralement la communication sans fil. Selon certains aspects, un équipement d'utilisateur (UE) peut recevoir une première communication d'informations de commande de liaison descendante (DCI) pour planifier un premier canal physique partagé de liaison descendante (PDSCH). Le premier PDSCH peut être associé à au moins un premier point d'émission réception (TRP). L'UE peut recevoir une seconde communication de DCI pour planifier un second PDSCH. Le second PDSCH peut être associé à un deuxième TRP et au premier TRP et/ou à un troisième TRP. L'UE peut recevoir des communications de liaison descendante en fonction, au moins en partie, de la première communication de DCI et de la seconde communication de DCI. L'invention se présente également sous de nombreux autres aspects.
Patent WO-2020142290-A1 (WO)
Inventor: WEINBERG ASSA
IPC: A61K31/4015
Filed: 2019-12-20
Abstract: L'invention concerne une méthode pour prévenir et traiter une perte auditive en utilisant des bloqueurs des canaux calciques, des inhibiteurs de l'enzyme de conversion de l'angiotensine (ACE), ou des bloqueurs des récepteurs de l'angiotensine (ARB), et plus particulièrement, une méthode pour prévenir et traiter une perte auditive en utilisant des bloqueurs des canaux calciques, des inhibiteurs de l'enzyme de conversion de l'angiotensine ou des bloqueurs des récepteurs de l'angiotensine qui ne sont pas pris par voie orale mais administrés par voie topique ou par injection, pour ainsi augmenter le réseau capillaire et l'apport en sang vers les tissus affectés, par exemple à travers l'espace de l'oreille externe et/ou l'espace de l'oreille moyenne et/ou l'espace de l'oreille interne pour former un contact avec l'appareil auditif de l'oreille.