baber/WOPTO huggingface dataset:
Patent AU-2021221064-B2 (AU)
Title: Pharmaceutical composition for inhibiting inflammatory response comprising hydroxyurea
Inventor: HWANG TAE-HO
IPC: A61P29/00
Filed: 2021-02-15
Granted: 2023-05-25
Abstract: The present invention relates to use of hydroxyurea for preventing, alleviating, or treating systemic inflammatory response syndrome or sepsis. Hydroxyurea, which is the active ingredient of a pharmaceutical composition of the present invention, can control the activity of neutrophils, which are immune cells involved in inflammatory mechanisms in an individual, and thus can protect an individual from side effects or conditions caused by systemic inflammatory responses which can occur due to exposure to microorganisms such as bacteria or viruses. Thus, when the pharmaceutical composition of the present invention is administered to an individual suffering from a systemic inflammatory response, the pharmaceutical composition prevents, alleviates, or treats systemic inflammatory response syndrome or sepsis in the individual and ultimately can remarkably increase the survival rate of the individual. In addition, the composition according to the present invention can be effective in preventing, alleviating, or treating neutrophilia which can occur when exposed to microorganisms such as bacteria or viruses, wherein the viruses include viruses for therapeutic purposes, such as oncolytic viruses, as well as pathogenic viruses such as influenza virus or coronavirus.
Patent JP-4482843-B2 (JP)
IPC: F16D65/18
Filed: 2000-03-31
Granted: 2010-06-16
Abstract: PROBLEM TO BE SOLVED: To provide a detecting method of pad abrasion of an electric disc brake capable of excellently detecting an abrasion quantity of a pad. SOLUTION: When the brake pad is abraded, a value M3 corresponding to pad clearance is subtracted from intermediate data M2 including the pad clearance and an abrasion quantity of the brake pad. The difference (corresponding to a pad abrasion quantity) M4(n) (M4(n)=M2-M3) is determined (Step S5). An operation of M4=M4(n-1)+M4(n) is performed. M4(n) is added to an abrasion quantity (M4(n-1)) of the brake pad till then, and a cumulative abrasion quantity M4 is determined (Step S7). The pad abrasion quantity can be quantitatively determined in real time.
Patent JP-3904179-B2 (JP)
IPC: G11B19/20
Filed: 2000-04-21
Granted: 2007-04-11
Abstract: The spindle motor is secured from turning which has bearings axially superimpose. The bearings consist of a base plate disk of an internal ring and an outer ring which is connected with an external rotor secured from turning. A labyrinth seal is arranged in the bearing lid which prevents oil from pouring from the bearing.
Patent JP-4504508-B2 (JP)
IPC: B23K20/24
Filed: 2000-04-26
Granted: 2010-07-14
Abstract: The shrouding (1,2) for a component surface is of a rubber elastic plastics material, fixed to the component (9,10) by adhes and which is resistant to high temps. The geometry of the shrouding (1,2), towards the component, accurately matches the geometr shape of the component. The thickness (D) of the shrouding (1,2) is set to meet the energy content and the kinetic energy of the metal splashes, with a defined min. thickness dimension which is not diminished.
Patent JP-3855646-B2 (JP)
IPC: G02F1/1337
Filed: 2000-11-16
Granted: 2006-12-13
Abstract: PROBLEM TO BE SOLVED: To obtain an optimum and uniform rubbing strength. SOLUTION: The illumination light from an illumination unit 85 is photographed by an CCD 84, and the real distance between the lower end of the rubbing roll surface and the referential plane is determined by a distance detecting circuit 86 from the photographed image by the CCD. The offset value of the device distance when the distance between the lower end face of the rubbing roll and the referential plane is zero is determined by the operation of a computer based on the real distance values at a plurality of measurement points. During rubbing, the offset value of the device distance is read out by a computer 87 from a memory 89 to determine the set value which gives specified rubbing strength and to drive a vertical movement motor 91. The offset value of the device distance has been determined with high accuracy so that the optimum and uniform rubbing strength can be obtained.
Patent JP-4616479-B2 (JP)
IPC: C07J41/00
Filed: 1999-10-15
Granted: 2011-01-19
Abstract: Substituted phenylalkenoylguanidines, processes for their preparation, uses as medicaments or diagnostics, and medicaments containing them are described. The invention relates to substituted phenylalkenoylguanidines and their pharmaceutically tolerable salts and physiologically functional derivatives of the formula in which the radicals have the meanings indicated, and their physiologically tolerable salts and processes for their preparation. The compounds are suitable as medicaments for the prophylaxis or treatment of gallstones.
Patent JP-3963650-B2 (JP)
IPC: B05D1/26
Filed: 2000-01-07
Granted: 2007-08-22
Abstract: The invention provides a nanolithographic method, comprising: (i) providing a substrate; (ii) providing a nanoscopic tip coated with a patterning compound; (iii) contacting the coated tip with the substrate so that the patterning compound is applied to the substrate to produce a desired pattern; and (iv) wherein the patterning compound is anchored to the substrate.
Patent JP-4721127-B2 (JP)
IPC: E05B85/10
Filed: 2000-06-21
Granted: 2011-07-13
Abstract: An outer door handle for vehicles has a stationary housing in the vehicle door. The handle has a handle arm and acts on a lock arranged within the door. A pivotable latching member serves as a mass latching mechanism and makes the handle actuatable in a release position. Because of its inertia in a crash situation, the latching member reaches an active support position and blocks the handle. The pivot bearing for the latching member is located on the stationary housing. The movable handle arm has a shoulder. A counter shoulder is provided on the latching member. The folding movement path of the shoulder on the handle arm is intersected by the pivot movement path of the counter shoulder. In a crash situation the shoulder comes to rest against the counter shoulder. In the release position, the shoulder passes the counter shoulder upon handle actuation.
Patent JP-4574930-B2 (JP)
IPC: H02M3/28
Filed: 2000-10-02
Granted: 2010-11-04
Abstract: An externally-driven synchronous rectifier circuit (18) comprises first and second synchronous rectifiers (SQ1, SQ2), and first and second synchronous rectifier recovery switches (SQ3, SQ5), and a pair of resonant inductors (LR1, LR2). The resonant inductors (LR1, LR2) store the energy normally loss during charging and discharging the input capacitance of the first and second synchronous rectifiers (SQ1, SQ2). The recovery switches (SQ3, SQ5) transfer the stored energy from the at least one inductor (LR) to the output terminal (Vout) creating a more energy efficient circuit (18).
Patent JP-4729222-B2 (JP)
IPC: C12N15/09
Filed: 2000-12-11
Granted: 2011-07-20
Abstract: The present invention provides compositions and methods for recombinational cloning. The compositions include vectors having multiple recombination sites with unique specificity The methods permit the simultaneous cloning of two or more different nucleic acid molecules. In some embodiments the molecules are fused together while in other embodiments the molecules are inserted into distinct sites in a vector. The invention also generally provides for linking or joining through recombination a number of molecules and/or compounds (eg, chemical compounds, drugs, proteins or peptides, lipids, nucleic acids, carbohydrates, etc) which may be the same or different Such molecules and/or compounds or combinations of such molecules and/or compounds can also be bound through recombination to various structures or supports according to the invention.
Patent JP-5096656-B2 (JP)
IPC: A23K1/10
Filed: 2001-01-15
Granted: 2012-12-12
Abstract: A composition is for feeding aquacultural prey organisms such as Artemia and rotifiers, comprising a lipid component comprising at least 25 wt % of phospholipids and providing a DHA content of at least 30 wt %. The lipid component is preferably derived from marine organisms such as fishmeal, phytoplankton or zoo plankton biomass. The composition is used for providing prey organisms having a high content of highly-unsaturated fatty acids (HUFAs) suitable for aquaculture of fish including halibut, turbot, bass and crustaceans and molluses.
Patent JP-4880851-B2 (JP)
IPC: C08J7/048
Filed: 2001-03-06
Granted: 2012-02-22
Abstract: A process for reducing the water-vapor permeability of films or coatings made from polymer compositions (Q) comprising beeswax or comprising montan ester wax or comprising mixtures of these, by preparing a composition (Z) comprising Z1) from 40 to 98.5% by weight of at least one polymer compatible with the polymer (Q1) which is the basis of Q, Z2) from 0.5 to 20% by weight of starch or cellulose or a mixture of these as compatibilizer, Z3) from 1 to 20% by weight of beeswax or montan ester wax or a mixture of these, and Z4) from 0 to 20% by weight of at least one additive, where the percentages by weight are based on the total weight of Z, and in a second step combining the composition Z with the polymer (Q1) which is the basis of Q.
Patent JP-3854154-B2 (JP)
IPC: C07C311/21
Filed: 2000-04-19
Granted: 2006-12-06
Abstract: The present invention provides compositions and methods for prevention and prophylaxis of neurological diseases accompanied by neuronal death. The invention includes synthesis of 5-benzylamino salicylic acid (BAS) and its derivatives. BAS and its derivatives protect cortical neurons from toxic insults by N-methyl-D-aspartate, Zn<2+>, and reactive oxygen species. Thus, the present invention provides compositions and methods for treating stroke, traumatic brain and spinal cord injury, epilepsy, and neurodegenerative diseases that are accompanied by severe neuronal loss via excitotoxicity, Zn<2+> neurotoxicity, and free radical neurotoxicity.
Patent JP-3951731-B2 (JP)
IPC: G02B5/20
Filed: 2002-02-08
Granted: 2007-08-01
Abstract: <P>PROBLEM TO BE SOLVED: To provide a color composition having excellent color characteristics, particularly high transparency and therefore, forming a color filter with high lightness, and to provide a color filter with high color characteristics.  <P>SOLUTION: The composition contains a coloring material carrier comprising a transparent resin, its precursor or a mixture of these, and a specified isoindoline pigment, for example, C.I.Pigment Yellow 185 dispersed in the coloring material carrier. The isoindoline pigment shows such spectral characteristics that when a yellow composition prepared by dispersing the pigment in the carrier is applied to form a coating film having 1% spectral transmittance at 435 nm, the spectral transmittance of the coating film is ≤3% at 475 nm and ≥80% at 505 nm. The color filter has a yellow or green filter segment formed from the above composition.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-3789101-B2 (JP)
IPC: G11B5/02
Filed: 2002-03-26
Granted: 2006-06-21
Abstract: <P>PROBLEM TO BE SOLVED: To provide a magnetic recorder and magnetic recording/writing method wherein a high density is achieved and writing mistakes are limited.  <P>SOLUTION: This magnetic recorder is provided with a magnetic recording medium 11 having a plurality of recording cells 12 cyclically arrayed along a recording track direction and nonmagnetic areas 13 for separating the recording cells 12, a magnetic field application recording means 16a for applying a magnetic field to the magnetic recording medium 11 to record information in the recording cell 12, a detection means 19 for detecting a leakage magnetic field 1d generated by application of the magnetic field of the magnetic field application recording means 16a, and control means 3, 4 for controlling a recording timing by the magnetic field application recording means 16a based on the detection of the leakage magnetic field 1d.  <P>COPYRIGHT: (C)2004,JPO
Patent JP-3851607-B2 (JP)
IPC: H01L23/12
Filed: 2002-11-21
Granted: 2006-11-29
Abstract: A semiconductor device production method including: the step of forming a stopper mask layer of a first metal on a semiconductor substrate, the stopper mask layer having an opening at a predetermined position thereof; the metal supplying step of supplying a second metal into the opening of the stopper mask layer to form a projection electrode of the second metal; and removing the stopper mask layer after the metal supplying step.
Patent JP-5175417-B2 (JP)
IPC: C12N15/09
Filed: 2001-08-15
Granted: 2013-04-03
Abstract: Compositions and methods for enhancing the effect of vaccines in animals, such as domestic, sport, or pet species, and humans are disclosed. More particularly, vaccine compositions comprising ribavirin and an antigen, preferably an antigen that has an epitope present in Hepatitis C virus (HCV), are disclosed for use in treating and preventing disease, preferably HCV infection.
Patent JP-4388742-B2 (JP)
IPC: C09J201/00
Filed: 2001-08-06
Granted: 2009-12-24
Abstract: Coated articles, methods for making such articles, and waterproofing systems incorporating these. An exemplary coated article comprises a body with surface coating of inorganic particles reactive with hydroxide generated from hydration of concrete or mortar to form hydration products. The articles are designed to be used with cast concrete or masonry. The inorganic particles comprise at least one of (a) aluminum oxide trihydrate; (b) silica dioxide; (c) fly ash; (d) blast furnace slag, (e) silica fume; (f) an alkali or alkaline earth metal salts; or mixture thereof. The particles improve bonding with hydratable cementitious compositions that are cast against the coated surface and allowed to set. <IMAGE>   <IMAGE>
Patent JP-4080885-B2 (JP)
IPC: C08F4/34
Filed: 2002-02-07
Granted: 2008-04-23
Abstract: The present invention relates to a process for the preparation of a peroxyester which can be used in particular in polymerizations, such as the polymerization of vinyl chloride, or in the thermosetting of polyester resins. This process comprises the reaction of a hydroxyhydroperoxide salt with an acid halide or an acid anhydride under the following conditions: the molar ratio R<SUB>b </SUB>of the hydroxyhydroperoxide corresponding to the hydroxyhydroperoxide salt to the acid halide is between 0.5 and 1.5; or alternatively the molar ratio R<SUB>b</SUB>' of the hydroxyhydroperoxide corresponding to the hydroxyhydroperoxide salt to the acid anhydride is between 1.0 and 3.0; the hydroxyhydroperoxide salt was prepared beforehand by reaction of the corresponding hydroxyhydroperoxide with a base according to a molar ratio R<SUB>a </SUB>of the base to the hydroxyhydroperoxide of between 0.5 and 1.5; and this process is carried out in aqueous media. The invention also relates to an aqueous emulsion comprising the peroxyester obtained and to a polymerization process employing a radical initiator comprising this peroxyester.
Patent JP-4224324-B2 (JP)
IPC: G09B29/00
Filed: 2003-03-04
Granted: 2009-02-12
Abstract: The bearing of a road segment indicates the direction that the segment follows from an end thereof. A primary bearing of a road segment is determined with respect to a significant shape point located along the road segment. The significant shape point is not necessarily the shape point closest to the end point, but is that shape point located within or beyond a predetermined range of distance from the end point. A secondary bearing is determined for some road segments. The secondary bearing indicates the general direction that a road segment follows leading away from an end point. The secondary bearing is determined using a view distance. The view distance is based on attributes of the road segment and represents an estimate of the distance of the driver's field of view as he/she approaches the intersection. Data indicating the primary and secondary bearing can be stored in a geographic database used by a navigation system. A navigation system application uses the primary and secondary bearing data to explicate driving maneuvers. <IMAGE>
Patent JP-3862084-B2 (JP)
IPC: B65H3/06
Filed: 2003-10-30
Granted: 2006-12-27
Abstract: In a sheet supplying device for feeding a sheet from a sheet stack configured by stacking plural sets of sheets collated by page order, each of which corresponds to one volume, for each set of sheets, in a state where the sheets are superimposed on one another so as to be sequentially offset from one another in a fore-to-aft direction, the sheet supplying device comprises: first transport means 2 for sucking a sheet in an uppermost position of a sheet stack P placed on a sheet table 1 so as to move the sheet rearward; second transport means 3 for sucking the sheet moved rearward by the first transport means 2 so as to transport the sheet forward; and a control unit 9 controlling suction operations of the first and second transport means 2, 3. The control unit 9 (i) allows the first transport means 2 to start the suction operation, and allows the first transport means 2 to suck the sheet in the uppermost position so as to move the sheet rearward, (ii) when it is determined on the basis of a detection signal from a sensor 4 that the sheet has reached a detection position of the sensor 4, allows the first transport means 2 to stop the suction operation and, also, the second transport means 3 to start the suction operation, allows the second transport means 3 to suck the sheet so as to transport the sheet forward, and allows the second transport means 3 to stop the suction operation, and (iii) repeats the operations (i) and (ii) for the subsequent sheets of the sheet stack P, until the sheets in a set of sheets, which corresponds to one volume, are all transported.
Patent JP-3993167-B2 (JP)
IPC: A43C15/16
Filed: 2002-05-17
Granted: 2007-10-17
Abstract: A shoe cleat connector for use with a receptacle attached to a shoe includes a substratum having a plurality of independent posts extending therefrom, with a retaining member disposed at a distal end and extending radially from each post. The receptacle includes a cavity with cantilevered fingers disposed near the periphery of the cavity. Each retaining member of the cleat connector includes a peripherally contoured series of adjacent planar surfaces that successively engage a corresponding cantilevered finger when the retaining members are inserted and rotated within the receptacle cavity, which results in the cleat connector being secured within the receptacle.</PTEXT>
Patent JP-4227020-B2 (JP)
IPC: A61B17/70
Filed: 2002-12-12
Granted: 2009-02-18
Abstract: The present invention relates to an implant providing osseous anchorage, for example in a vertebra for anchoring an osteosynthesis device. This implant comprises a fixation head capable of receiving a bar linking a plurality of implants in different angular positions. This osseous anchoring implant comprises fixation means capable of receiving and fixing at least one bar, in particular of osteosynthesis, characterized in that these fixation means comprise at least one element enabling, prior to the blocking of the fixation, a determined clearance in rotation around at least one first axis not parallel to the longitudinal axis of the bar. The fixation head is moving relative to the osseous anchoring part according to an articulation enabling freedom in rotation around at least two axes mot merged with the longitudinal axis of the bar, so that the implant may also enable a clearance in rotation around at least two axes not parallel one to another, constituting a tilting of the head relative to the anchorage axis, and a rotation of the head around this axis. The movements are then blocked by the clamping of the fixation means.
Patent JP-4589626-B2 (JP)
IPC: C07D215/50
Filed: 2002-12-13
Granted: 2010-12-01
Abstract: An article of manufacture marked with compositions comprising rare earth metal compounds which, due to their luminescence when irradiated with UV light, are suitable in particular for the marking of security-relevant items, such as documents or data carriers.
Patent JP-4144800-B2 (JP)
IPC: A61P31/04
Filed: 2002-01-31
Granted: 2008-09-03
Abstract: The present invention relates to a composition comprising a catechin compound, ascorbic acid, proline and lysine. The present invention also relates to a method for treating neoplastic disease using a composition comprising a catechin compound, ascorbic acid, proline and lysine.
Patent JP-4541008-B2 (JP)
IPC: A61F2/00
Filed: 2004-03-19
Granted: 2010-09-08
Abstract: A stent or other intraluminal medical device uses a series of anvil bridges interposed between a series of fixed bridges to reduce the likelihood of deformation during stent loading and stent deployment without sacrificing overall stent flexibility. The stent comprises a plurality of hoops interconnected by a plurality of fixed bridges. The stent also comprises a plurality of anvil bridges, which transmit forces only when the stent is subjected to compressive axial loading. The stent may also comprise markers formed from housings integral with the stent and marker inserts having a higher radiopacity than the stent. This design provides for more precise placement and post-procedural visualization in a vessel, by increasing the radiopacity of the stent under X-ray fluoroscopy. The housings are formed integral to the stent and the marker inserts are made from a material close in the galvanic series to the stent material and sized to substantially minimize the effect of galvanic corrosion. The housings are also shaped to minimize their impact on the overall profile of the stent. <IMAGE>
Patent JP-4209811-B2 (JP)
IPC: G10L21/003
Filed: 2004-05-25
Granted: 2009-01-14
Abstract: <P>PROBLEM TO BE SOLVED: To provide a voice selection device that can obtain a synthesized voice at high speed that sounds natural, using a simple configuration.  <P>SOLUTION: This voice selection device is built up so that, when the data representing a template message are supplied, the voice fragment compiler 8 makes the voice fragment database 10 output the voice fragment data having the similar reading and converts the voice fragment data to match the speed shown by the pronunciation speed data. The voice fragment compiler 8 predicts the rhythm of the template message, and specifies the one which best matches the template message from the outputted voice fragment data according to the evaluation formula. The evaluation formula has as a variable the result of a primary regression of the frequency of the pitch component in between rhythm prediction result/voice fragment data. This voice selection device puts together the specified voice fragment data and the waveform data supplied to the voice processor 4 instead, since it cannot be specified and generates the data representing the synthesized voice.  <P>COPYRIGHT: (C)2005,JPO&NCIPI
Patent JP-4689977-B2 (JP)
IPC: H01L29/78
Filed: 2004-06-17
Granted: 2011-06-01
Abstract: A lateral power metal-oxide-semiconductor field effect transistor (MOSFET) having a gate structure in which the insulated gate (28,28A,28B) is coupled to a further gate electrode layer (25) through contacts (31,33,34) at a plurality of locations. The source electrode (21) includes first (21A) and second (21B) segments. The first segment (21A) is interposed between the drain electrode (22A) and the gate electrode layer (25), has no direct contact to the source region (44), does not carry a significant amount of source current, and acts as a field plate.