baber/WOPTO huggingface dataset:
Patent EP-3850094-A1 (EP)
Inventor: MICCIO ANNARITA
IPC: C12N15/10
Filed: 2019-09-10
Abstract: The clinical severity of β-hemoglobinopathies is alleviated by the co-inheritance of genetic mutations causing a sustained fetal γ-globin chain production at adult age, a condition termed hereditary persistence of fetal hemoglobin (HPFH). Here, the inventors have compared the extent of fetal hemoglobin (HbF) de-repression following CRISPR/Cas9-mediated targeting of different regions of the  HBG1  and  HBG2  promoters in an adult erythroid cell line (HUDEP- 2). They achieved a potent and pancellular HbF re-activation upon disruption of binding sites for γ-globin repressors located in both  HBG1  and  HBG2  genes. They validated these findings in Red Blood Cells (RBCs) derived from genome edited Sickle Cell Disease (SCD) patient hematopoietic stem/progenitor cells. Overall, this study identified a binding site for an HbF repressor as a novel and potent target for the treatment of β-hemoglobinopathies. Accordingly, the present invention relates to a method for increasing fetal hemoglobin content in a eukaryotic cell comprising the step of disrupting the binding site for Leukemia/lymphoma-related factor (LRF) in the HBG1 or HBG2 promoter.
Patent EP-3841780-A1 (EP)
Inventor: PULARIKKAL GANGADHARAN BYJU
IPC: H04L47/80
Filed: 2019-08-16
Abstract: Systems, methods, and devices are disclosed for providing a quality of service between nodes. A service provider can receive, from a first node of a customer network to an ingress node of a service provider network, packets bound for a second node on the customer network that is remote from the first node. The packets are mapped to a network segment according to a traffic type based on an identifier associated with the packets that identifies the traffic type of the packets. The packets are sent via their mapped network segment to an egress node with connectivity to the second node of the customer network according to a quality of service associated with the traffic type identified by the identifier.
Patent EP-3853679-A1 (EP)
Title: Verfahren zur zustandsanalyse eines elektromechanischen fügesystems und elektromechanisches fügesystem zur durchführung dieses verfahrens
Inventor: MüLLER ALEXANDER
IPC: G05B19/4065
Filed: 2019-09-12
Abstract: Die Erfindung betrifft ein Verfahren zur Zustandsanalyse eines elektromechanischen Fügesystems (100) sowie ein zum Durchführen des Verfahrens ausgebildetes elektromechanisches Fügesystem (100); wobei durch einen elektrischen Antrieb (10) mittels eines Gewindetriebs (20) eine Ausgangskraft oder ein Ausgangsdrehmoment für einen durch das elektromechanische Fügesystem (100) durchgeführten Fügeprozess erzeugt wird; wobei einer Kontrolleinrichtung (14) Ist-Werte (IW, IW') des elektrischen Antriebs (10) als Eingangsgrösse zugeführt werden; wobei von einem Sensor (24) zusätzliche Messwerte (ZMW) ermittelt werden, welcher Sensor (24) zur Messung von Kraft- oder Drehmomentverläufen während des Fügeprozesses dient; dass die zusätzlichen Messwerte (ZMW der Kontrolleinrichtung (14) als Eingangsgrösse zugeführt werden; und wobei die Kontrolleinrichtung (14) aus einer Verknüpfung der zugeführten Ist-Werte (IW, IW') mit den zugeführten zusätzlichen Messwerten (ZMW) einen sich anbahnenden Verschleisses einer verschleissbehafteten Komponente (21) des elektromechanischen Fügesystems (100) detektiert.
Patent EP-3841693-A1 (EP)
Inventor: LIN JAMIE MENJAY
IPC: H04L1/00
Filed: 2019-08-22
Abstract: Methods, systems, and devices for wireless communications are described. A wireless device, such as a user equipment (UE) may monitor for a decoding candidate of a codeword, wherein the codeword corresponds to a set of received bit metrics, and the decoding candidate corresponds to a plurality of information bits encoded using a polar code, determine a composite detection metric for the codeword for the decoding candidate, where the composite detection metric is derived from a subset of bit metrics for an intermediate polarization layer of the polar code, and determine a classification for performing a list decoding process on the codeword according to the decoding candidate based at least in part on the composite detection metric.
Patent EP-3833328-A1 (EP)
Title: Composition containing a mucolytic agent for the treatment of mucus hypersecretion and a device for the dosing thereof
Inventor: BIFFI ANDREA
IPC: A61K47/26
Filed: 2019-08-07
Abstract: The present invention regards a composition in powder form for oral inhalation, preferably for oral aspiration, comprising a mucolytic agent, preferably N-acetylcysteine. Furthermore, the present invention regards said composition for use in a method for the treatment of a mucus hypersecretion and of diseases, symptoms or disorders associated with it in a needy subject. Lastly, the present invention regards a device for administration, through inhalation route by means of oral aspiration, to said needy subject.
Patent EP-3856337-A1 (EP)
Inventor: PULEO CHRISTOPHER MICHAEL
IPC: A61N1/36
Filed: 2019-08-30
Abstract: The subject matter of the present disclosure generally relates to techniques for following a treatment protocol having one or more treatment parameters to cause a targeted physiological outcome at a distal site, assessing an expression level of a gene in a region of interest after completing the treatment protocol, and modifying the one or more treatment parameters based on the expression level of the gene. The treatment protocol may include one or more ultrasound energy treatments to the region of interest.
Patent EP-3834084-A1 (EP)
Inventor: MOSS ALON
IPC: G06F9/455
Filed: 2019-08-09
Abstract: A test server system provides a test server (5) situated behind an enterprise network firewall (4). The test server is arranged to capture an up to date image of all the information processing devices (1.1-3.3) integrated with the enterprise network. When a new (or updated) program module (NPM) is to be installed on the whole or any part of the enterprise network, the NPM installation is first run against an emulation of the enterprise network devices and any existing core program modules (CPM) (1.1'-3.3') in the test server. A predetermined test protocol is tailored to the specific enterprise network and designed to ensure that installation of the NPM does not result in serious adverse effects on the effective operation of the emulated enterprise network for instance due to conflicts with other CPMs. In particular the tests applied to the emulated enterprise network can be applied to programs or configurations which are proprietary to the enterprise and often mission critical. The test server is arranged to be controlled from a data centre server (1) outside the enterprise network firewall. Where adverse effects are detected in emulation the test server prevents installation of the NPM to the real enterprise network. The test serve can identify indices relevant to the fault and use such indices in a database correlating known fixes with the fault. Selected fixes can be applied to the emulated enterprise network for testing with the NPM. Where this results in no-fault condition the selected effective fix and NPM is applied to the real system.
Patent EP-3856991-A1 (EP)
Title: Partition comprising boards mounted onto upright elongate members and method for constructing the same
Inventor: RIDEOUT JAN
IPC: E04B2/74
Filed: 2019-09-10
Abstract: A partition (10), mounted on a mounting surface, comprises a plurality of elongate upright members (16,18), a first board (20) and a second board (22). The first board is mounted on one side of a pair of the elongate upright members that are adjacent to each other, and the second board is mounted on the other side of the same pair of adjacent elongate upright members, so as to provide a cavity (24) between the pair of elongate upright members and the first and second boards. The partition further comprises a spacer (26) that is located within the cavity, the maximum dimension of the spacer in the through-thickness direction of the partition being at least 90% of the separation of the two boards. The spacer may help to reduce the extent of inward bowing of the boards between adjacent elongate upright members, so that, for example, the upright members may be spaced further apart
Patent EP-3863988-A1 (EP)
Inventor: PFEIL ARMIN
IPC: C04B14/28
Filed: 2019-10-02
Abstract: The present invention pertains to a two-component inorganic injection mortar system comprising a curable aqueous-phase aluminous cement component A and an initiator component B in aqueous-phase for initiating the curing process, component A further comprising at least one blocking agent selected from the group consisting of phosphoric acid, metaphosphoric acid, phosphorous acid and phosphonic acids, at least one plasticizer and water, and component B comprising an initiator, at least one retarder, at least one mineral filler and water, characterized in that the curable aqueous-phase aluminous cement component A comprises calcium aluminate cement having an average particle size in the range of from 0.5 to 15 µm. Moreover, the present invention pertains to a two-component system, which is ready-for-use, for chemical fastening of anchoring means, preferably of metal elements, in mineral substrates, such as structures made of brickwork, concrete, pervious concrete or natural stone as well as its use for chemical fastening of anchoring means.
Patent EP-3852970-A1 (EP)
Inventor: TORO ANDREA
IPC: B65G47/24
Filed: 2019-09-18
Abstract: An orientation device for objects (O) provided with a stem (S) and with a head (H) that has a minimum width (R), characterised in that it comprises: a slot (3) which has two edges separated by a predetermined distance (D), less than the minimum width (R) and greater than the maximum width of the stem (G); an uncoupling device (4), movable between an active configuration, in which it is able to retain an object (O) with respect to lifting, and an inactive configuration, in which it is not able to interact with an object (O); a magnetic gripping element (2), movable along at least a vertical direction between an upper position and a lower position, in which an object (O) associated with the gripping element (2) is in a position such as to be retained by the uncoupling device (4) so as to be detached from the gripping element (2).
Patent EP-3776692-A1 (EP)
Title: Solid state batteries, sse batteries, lithium metal batteries with solid state electrolytes, hsse, separators, and/or coatings, and/or related methods
Inventor: ZHANG ZHENGMING
IPC: H01M50/409
Filed: 2019-04-04
Abstract: Larger SSE batteries comprises interface or interfacial layer at least between the anode, which comprises Li or Na, and the solid state electrolyte (SSE). An interfacial layer may be provided between the anode, which comprises Li or Na, and the SSE, and an interface or interfacial layer may also be provided between the cathode and the SSE. The interfacial layer may prevent or deter lithium deposition and dendrite growth at the interface between the anode and the SSE. The interfacial layer may be a porous polymer layer filled with liquid electrolyte and may improve ionic conductance between the anode and the SSE and/or the SSE and the cathode. The anode interface or interfacial layer may be a porous polymer layer filled with liquid electrolyte. The cathode interface or interfacial layer may be a porous polymer layer filled with liquid, gel or polymer electrolyte.
Patent EP-3779997-A1 (EP)
Title: Medical document display control device, medical document display control method, and medical document display control program
Inventor: HIRAKAWA SHINNOSUKE
IPC: A61B5/00
Filed: 2019-03-20
Abstract: The medical document display control apparatus includes a reception unit that receives observation information on a subject, an acquisition unit that acquires relation information on an analysis result obtained by immediately analyzing the observation information received by the reception unit, and a display control unit that immediately displays the relation information acquired by the acquisition unit on a display unit.
Patent EP-3849790-A1 (EP)
Inventor: BLADD-SYMMS PETER
IPC: B32B5/24
Filed: 2019-09-13
Abstract: L'invention concerne une feuille structurale ou un panneau de protection, comprenant une couche de polyoléfine auto-renforcée ; une couche de mousse polymère, la couche de polyoléfine auto-renforcée et la mousse polymère étant liées ensemble pour former une structure stratifiée. Les feuilles structurales (seules ou en combinaison avec d'autres feuilles structurales) peuvent être configurées en tant que structures de protection. L'invention concerne également des panneaux de protection, des panneaux de toit, des volets de fenêtre ou de porte, des planches de roulement et des panneaux de clôture.
Patent EP-3783825-A1 (EP)
Inventor: ZHANG SHUJUAN
IPC: H04L5/00
Filed: 2019-04-16
Abstract: Disclosed are a method and device for determining a quasi co-located (QCL) reference signal set. The method comprises: selecting N2 control channel resources from control channel resources contained in N1 time units, wherein N1 and N2 are integers greater than or equal to 1; and determining, according to the N2 control channel resources, at least M QCL reference signal sets of M port sets, wherein M is an integer greater than or equal to 1. In the embodiments of the present disclosure, at least M QCL reference signal sets of M port sets are determined on the basis of selected N2 control channel resources, such that signals or channels transmitted by two or more TRPs are received on the basis of the at least M QCL reference signal sets of the M port sets.
Patent EP-3873216-A1 (EP)
Inventor: ASENSIO LUIS
IPC: A21C11/04
Filed: 2019-10-31
Abstract: This pinching-shaping device comprises at least one pair of cylindrical tools (100, 200), which each have a central axis (X100, X200) around which the tool is rotated and which are designed so that the central axes are parallel and so that the outer peripheries of the tools are applied tangentially one against the other in order to pinch-shape a strip (2) tangentially introduced between the tools during their rotation. The outer periphery of each tool is provided with radially projecting blades that are successively distributed around the central axis and which each provide a pinching surface. The pinching surface extends between the first end thereof and the second end thereof in a manner inclined with respect to the central axis. In order to obtain novel shapes of products (1) in a simple and economic manner, the blades of each tool are distributed, following the outer periphery of the tool, alternating in inclination such that, each time that one of the blades of a first of the two tools is radially interposed between the two tools during the rotation of the tools, this blade of the first tool is radially aligned with one of the blades of the second tool, the pinching surface of which is inclined in a complementary manner with the pinching surface of this blade of the first tool, in order to pinch the strip between the respective pinching surfaces of these two aligned blades.
Patent EP-3824417-A1 (EP)
Title: Verfahren und system zum prognostizieren eines ausfalls einer ventilatorgruppe sowie entsprechende ventilatorgruppe
Inventor: WENGER BJOERN
IPC: G06Q10/00
Filed: 2019-10-09
Abstract: Es ist ein Verfahren zum Prognostizieren eines Ausfalls einer Ventilatorgruppe mit N Ventilatoren, von denen n Ventilatoren redundant sind, wobei 1 < n ≤ N. Dabei liegt bei Ausfall von n Ventilatoren ein Ausfall der Ventilatorgruppe vor. Die Ausfallwahrscheinlichkeiten der Ventilatoren sind als Funktion einer Betriebsdauer der Ventilatorgruppe durch eine Wahrscheinlichkeitsverteilung beschreibbar, wobei die Wahrscheinlichkeitsverteilung zumindest durch einen Parameter parametrierbar ist. Das Verfahren umfasst die Schritte: Erzeugen einer ersten Ausfallwahrscheinlichkeit, die eine Wahrscheinlichkeit eines ersten Ausfalls eines Ventilators der Ventilatorgruppe angibt, Erzeugen einer n-ten Ausfallwahrscheinlichkeit, die eine Wahrscheinlichkeit eines n-ten Ausfalls eines Ventilators der Ventilatorgruppe angibt, Ermitteln eines ersten Ausfallzeitpunkt, wobei der erste Ausfallzeitpunkt die Betriebsdauer der Ventilatorgruppe bis zum ersten Ausfall eines Ventilators angibt, Erzeugen einer parametrierten Wahrscheinlichkeitsverteilung durch Approximieren der Wahrscheinlichkeitsverteilung an ein erstes Wertepaar bestehend aus der ersten Ausfallwahrscheinlichkeit und dem ersten Ausfallzeitpunkt und Berechnen des n-ten Ausfallzeitpunkts als Zeitpunkt des n-ten Ausfalls eines Ventilators mittels der parametrierten Wahrscheinlichkeitsverteilung und der n-ten Ausfallwahrscheinlichkeit. Es ist ferner ein entsprechendes System sowie eine Ventilatorgruppe mit einem derartigen System beschrieben.
Patent EP-3871018-A1 (EP)
Inventor: DOSSARY SALEH A
IPC: G01V1/36
Filed: 2019-10-23
Abstract: Seismic image processing including filtering a three-dimensional (3D) seismic image for random noise attenuation via multiple processors. The filtering includes receiving a 3D image cube of seismic image data, decomposing the 3D image cube into 3D sub-cubes for parallel computation on the multiple processors, designing and applying a two-dimensional (2D) adaptive filter for image points on 2D image slices of the 3D sub-cubes via the multiple processors to give filtered 3D sub-cubes, and summing the filtered 3D sub-cubes to give a filtered 3D image cube.
Patent EP-3793600-A1 (EP)
Inventor: STAUTON DONALD E
IPC: C07K16/18
Filed: 2019-05-15
Abstract: Embodiments of the present disclosure relate to the composition of bispecific antibodies against cadherin-17 and CD3 and method of using the antibodies for cancer treatment.
Patent EP-3886996-A1 (EP)
Inventor: MENDROK-EDINGER CHRISTINE
IPC: A61Q19/00
Filed: 2019-11-26
Abstract: The present invention relates to cosmetic compositions which comprise a hyperbranched copolymer of the monomers dodecenyl succinic acid anhydride, diisopropanol amine and bis-dimethylaminopropyl amine having quaternary terminal groups and at least one liquid dispersion of an acrylic polymer which is a homopolymer or a copolymer of the monomers selected from the group consisting of (meth)acrylic acid, (meth)acrylic esters, (meth)acrylamide and amides of (meth) acrylic acid.
Patent EP-3890520-A1 (EP)
Inventor: JOYEUX THIERRY
IPC: A24D3/06
Filed: 2019-12-05
Abstract: There is provided an aerosol-generating article (10) comprising an aerosol-generating substrate (12) and a filter (14) in axial alignment with the aerosol-generating substrate (12). The filter (14) comprises at least one segment of filtration material formed of one or more sheets of a fibrous paper-like material. The fibrous paper-like material comprises a combination of hydrophobic fibres and hydrophilic fibres such that the fibrous paper-like material has a water contact angle as measured in accordance with TAPPI/ANSI T 558 om-15 greater than 90 degrees. Further, the fibrous paper material has a biodegradability in aqueous medium as tested in accordance with ISO 14851 (2005) of at least 90 percent of the maximum degradation of a cellulose reference item within 56 days of testing. In addition, the hydrophobic fibres comprise hydrophobic viscose fibres.
Patent EP-3806461-A1 (EP)
Inventor: KO GEONJUNG
IPC: H04N19/593
Filed: 2019-06-07
Abstract: A video signal processing method and apparatus for encoding or decoding a video signal are disclosed. More specifically, disclosed are a method for processing a video signal and a video signal processing apparatus for performing same, the method comprising the steps of: forming a motion vector prediction (MVP) candidate list for motion compensation of a current block by using either a first method or a second method; acquiring an MVP of the current block on the basis of the formed MVP candidate list; acquiring a motion vector differential value indicating a difference between a motion vector and the MVP of the current block; correcting the motion vector differential value on the basis of the resolution of the motion vector differential value of the current block, wherein the resolution of the motion vector differential value is any one of a plurality of available resolutions included in a resolution set, and the configuration of the plurality of available resolutions included in the resolution set varies according to which of the first method and the second method is used to form the MVP candidate list of the current block; acquiring a motion vector of the current block on the basis of the MVP and the corrected motion vector differential value; and reconstructing the current block on the basis of the acquired motion vector.
Patent EP-3715431-A1 (EP)
Inventor: YUN HA SONG
IPC: C09J11/06
Filed: 2019-06-05
Abstract: The present application relates to a pressure-sensitive adhesive composition and a use thereof. The polarizing plate to which the pressure-sensitive adhesive composition of the present application is applied has an advantage that the performance capable of blocking the blue light, for example, the light having a wavelength region of 380 nm or more, is particularly excellent, when attached to an organic light emitting panel, especially, an organic light emitting panel comprising a plastic substrate.
Patent EP-3894646-A1 (EP)
Inventor: CONAN HERVE
IPC: E05B81/76
Filed: 2019-12-09
Abstract: The invention concerns a handle (1) of a door (30), in particular a motor vehicle door, characterised in that it comprises: - a body (2) intended to be mounted so as to be movable for the disengagement of at least one lock of the door by displacement, in particular by displacement by pulling the body (2) relative to a door; and - a tumbler (5) mounted so as to be movable relative to the body (2) between an idle position and an activation position, so as to be able to reach the activation position by pressing on the tumbler (5) to disengage the lock of the door. The invention also concerns a door comprising such a handle and a vehicle comprising such a door.
Patent EP-3891512-A1 (EP)
Inventor: KRISHNA SESHADRI ARJUN
IPC: B60W40/00
Filed: 2019-12-03
Abstract: A method of providing an indication of driving performance involves obtaining a forward acceleration and speed of a vehicle. A forward acceleration threshold value is identified for use in identifying excessive forward acceleration of the vehicle based on the determined speed of the vehicle. For any vehicle speed within a range of vehicle speeds, the acceleration threshold value is defined by a function based on the determined speed of the vehicle, wherein the forward acceleration threshold value according to the function varies continually with vehicle speed over the range of vehicle speeds. The determined forward acceleration of the vehicle is compared with the determined acceleration threshold value, and an indication of an excessive forward acceleration driving event is generated when the determined forward acceleration exceeds the determined acceleration threshold value.
Patent EP-4074007-A1 (EP)
Inventor: DAUNERIA ANKUR
IPC: H04W4/12
Filed: 2019-12-13
Abstract: The present disclosure provides a mechanism supporting event notifications for dynamic group events targeting any user (e.g. all users) in a specified target area. The target area for the dynamic group event is user-defined (i.e., defined by the advertiser) and can be based on a priori information. For example, the target area for a dynamic group event can be a traffic signal location, an area within a shopping mall, a historic site, a venue for a sporting event or trade fair, other locations where dynamically created groups are likely to occur. In some embodiments, the dynamic group event includes an option to receive updates when a user within a target area establishes a Packet Data Unit (PDU) session after entering the target area but before leaving. Also, the dynamic group event can include alternating periods for reporting and non-reporting, which is useful, for example, in the traffic signal scenario to synchronize the network-initiated streaming with the traffic signal pattern.