baber/WOPTO huggingface dataset:
Patent NZ-336838-A (NZ)
Title: A method of enhancing the level of perfusion of blood to a target tissue by administering an adenoviral vector encoded with an angiogenic peptide within 0.5-15 cm3 of the tissue
Inventor: ROSENGART TODD K
IPC: A61K38/00
Filed: 1998-01-29
Abstract: A method for enhancing the level of perfusion of blood to a target tissue, treating a target tissue suffering from or at risk of suffering from ischemic damage, inducing angiogenesis in a target tissue, and/or inducing collateral blood vessel formation in a target tissue affected by or at risk of being affected by a vascular occlusion. The method comprises administering to the target tissue a dose of a pharmaceutical composition comprising (a) a pharmaceutically acceptable carrier and (b) an adenoviral vector comprising a DNA encoding an angiogenic peptide, such that the level of perfusion of blood to the target tissue is enhanced, the dose has a therapeutic or prophylactic effect on the target tissue, angiogenesis is induced in the target tissue, and/or the adenoviral vector contacts a region including the source, the terminus, and an area between the collateral blood vessel formation, and collateral blood vessel formation is induced.
Patent NZ-504628-A (NZ)
Title: Resealable packaging comprising a tearable welded seam
Inventor: ENGELAERE JEAN-CLAUDE
IPC: B65D77/20
Filed: 2000-05-18
Abstract: The reclosable packaging comprises:  a container (A) with a support layer, complexable layer, pressure-sensitive polyurethane-adhesive layer and tearable welding layer, the structure (C) comprising the layers and being laid on the support layer; facing the container;  a cover member or lid having a welding layer and a support layer with a tearable welding layer welded upon seam (D).  The package can be readily opened and reclosed.
Patent NZ-505312-A (NZ)
Title: Recombinant Vesicular Stomatitis virus comprising a heterologous F protein (Paramyxovirus strain SV5) and CD4 antireceptor protein
Inventor: WHITT MICHAEL A
IPC: C12N15/86
Filed: 1998-12-22
Abstract: Described is a composition comprising a recombinant or genetically engineered Rhabdovirus that expresses a Fusion Protein, such as the F protein of the Paramyxovirus SV5 strain.  This recombinant Rhabdovirus may express other non-Rhabdovirus attachment proteins and/or an enhancer protein.  Also described are methods of making recombinant Rhabdoviruses that express an F Protein.  These recombinant compositions can be used for purposes of research, as well as for diagnostic and therapeutic compositions for treatment of diseases.
Patent NZ-508160-A (NZ)
Title: Methods for treating neuropsychiatric disorders
Inventor: TSAI GUOCHUAN
IPC: A61K31/198
Filed: 1999-04-14
Abstract: The use of a therapeutic agent selected form the group consisting of D-alanine, a salt of D-alanine, an ester of D-alanine, alkylated D-alanine, a precursor of D-alanine, D-serine, a salt of D-serine, alkylated D-serine, an ester of D-serine having 4-20 carbon atoms, and a precursor of D-serine; for the preparation of a medicament for treating a neuropsychiatric disorder selected from the group consisting of schizophrenia, Alzheimer's disease, autism, depression, benign forgetfulness, a childhood learning disorder, attention deficit disorder, and closed head injury, wherein when the therapeutic agent is D-alanine, a salt of D-alanine, an ester of D-alanine, an alkylated D-alanine, or a precursor of D-alanine, the medicament is substantially free of D-cycloserine.
Patent NZ-519272-A (NZ)
Title: Substituted imidazole neuropeptide Y Y5 receptor antagonists
Inventor: STAMFORD ANDREW W
IPC: A61P3/00
Filed: 2000-12-14
Abstract: Selective 4-(phenyl or pyridyl)-imidazole derative neuropeptide Y Y5 receptor antagonists of formula (I) useful in the treatment of eating disorders or diabetes and pharmaceutical compositions containing the compounds.
Patent NZ-520461-A (NZ)
Title: Automated diagnostic system and method
Inventor: ILIFF EDWIN C
IPC: G16H10/60
Filed: 2001-02-14
Abstract: A system for automatically diagnosing a disease comprises: a first disease symptom object associated with set of first disease symptom objects with at least one of disease symptom objects having an actual symptom weight and a second disease object associated with set of second disease symptom objects with at least one second disease symptom object corresponding to the at least one first disease symptom object and having an alternative symptom weight; wherein the alternative symptom weight is applied to a diagnostic score so as to automatically diagnose the disease. A system for automated medical diagnosis of a patient comprises: means for providing at least a first symptom element having a first symptom weight; means for retrieving an alternative weight for the first symptom; and means for applying the retrieved alternative weight to a diagnostic score so as to automatically diagnose a medical condition. A computerized diagnostic system utilizing a predicted timeline of symptoms comprises: a computerized device; a database, in data communication with the computerized device, having a plurality of timelines which are each representative of a typical course of a disease via a characteristic pattern of symptom magnitudes over time and a diagnosis program on the computerized device. The diagnosis program configured to: automatically ask one or more questions of a patient so as to elicit a symptom indicative of a chief complaint; automatically receive answers from the patient in response to the questions; automatically identify a disease corresponding to the chief complaint; correlate the chief complaint to a one of the plurality of timelines for the identified disease; automatically ask one or more questions to elicit the presence and time of a first significant symptom on the timeline for the identified disease; add an incremental weight to a cumulative score for the disease if the first significant symptom is established, and establish the diagnosis when the cumulative score exceeds a predetermined threshold.
Patent NZ-520630-A (NZ)
Title: Drospirenone for hormone replacement therapy
Inventor: HEIL WOLFGANG
IPC: A61K31/565
Filed: 2001-01-18
Abstract: A pharmaceutical composition comprising as a first active ingredient an estrogen, such as estradiol or estradiol valerate, in sufficient amounts to treat disorders and symptoms associated with deficient endogenous levels of estrogen in women, and as a second active ingredient 6 beta , 7 beta ; 15 beta ; 16 beta -dimethylene-3-oxo-17 alpha -preg-4-ene-21, 17-carbolactone (drospirenone, DRSP) in sufficient amounts to protect the endometrium from the adverse effects of estrogen is useful for, amongst others, treating peri-menopausal, menopausal and post-menopausal women. This composition may be used for hormone replacement therapy and may be administered as a multi-phased pharmaceutical preparation. This combination therapy may comprise continuous, sequential or interrupted administration, or combinations thereof, of DRSP and estrogen, each optionally in micronized form. Uses disclosed include for the treatment of hot flushes, sweating attacks, palpitations, sleep disorders, mood changes, nervousness, anxiety, poor memory, loss of confidence, loss of libido, poor concentration, diminished energy, diminished drive, irritability, urogenital atrophy, atrophy of the breasts, cardiovascular disease, changes in hair distribution, thickness of hair, changes in skin condition or for the prevention or management of osteoporosis.
Patent NZ-520878-A (NZ)
Title: Method for preparing 9-deoxo-8a-aza-(8a-alkyl)-8a-homoerythromycin A derivatives from 9-deoxo-9(Z)-hydroxyiminoerythromycin A
Inventor: LEON PATRICK
IPC: C07H17/00
Filed: 2001-03-23
Abstract: A process for the preparation of 9-deoxo-8a-aza-8a-homoerythromycin A of formula V via the stereospecific Beckman rearrangement.
Patent NZ-520941-A (NZ)
Title: On-site agricultural product analysis system and method of analyzing
Inventor: HALL ALLEN L
IPC: G01N21/35
Filed: 2001-03-09
Abstract: A method of characterizing an agricultural product at a location comprises: analyzing an agricultural product with at least one sensor to generate and acquire data; transmitting the acquired data by a telecommunication link to a central processor; manipulating the acquired data by the central processor to calculate the value of at least one property characterizing the agricultural product, the central processor containing a library of calibration models; and transmitting the data measurement by the telecommunication link to display in the vicinity of the sensor.
Patent NZ-521060-A (NZ)
Title: Pharmaceutically active pyrrolidine derivatives as bax inhibitors and method of preparation thereof
Inventor: HALAZY SERGE
IPC: A61K31/402
Filed: 2001-03-20
Abstract: Pyrrolidine derivatives of formula (I) their preparation process and use thereof, pyrrolidine derivatives of formula (I) are useful in the treatment and/or prevention of premature labor, premature birth and dysmenorrhea; these pyrrolidine derivative compounds are also useful in the treatment and/or prevention of disease states mediated by oxytocin, including premature labor, premature birth and dysmenorrhea, as they particularly display a substantial modulatory, notably an antagonist activity of the oxytocin receptor; wherein: X is selected from the group consisting of CR6R7, NOR6, NNR6R7; A is selected from the group consisting of -(C=O)-, -(C=O)-O-, -C(=NH)-, -(C=O)-NH-, -(C=S)-NH, -SO2-, -SO2NH-, -CH2-; B is either a group -(C=O)-NR8R9 or represents a heterocyclic residue having the formula (a) wherein: Q is NR10, O or S; n is 0, 1 or 2; Y, Z and E form together with the 2 carbons to which they are attached a 5-6 membered aryl or heteroaryl ring; R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11 are as described in the specification.
Patent NZ-523879-A (NZ)
Title: Novel aminocyclohexane derivatives, their manufacture and their use as 2,3-oxidosqualene-lanosterol cyclase inhibiting medicaments
Inventor: ACKERMANN JEAN
IPC: C07D309/12
Filed: 2001-08-08
Abstract: Aminocyclohexanol derivatives their salts and esters that are useful for the treatment and/or prophylaxis of diseases which are associated with 2,3-oxidosqualene-lanosterol cyclase such as hypercholesterolemia, hyperlipemia, arteriosclerosis, vascular diseases, mycoses, gallstones, tumors and/or hyperproliferative disorders, and treatment and/or prophylaxis of impaired glucose tolerance and diabetes are disclosed, wherein: U is O or a lone pair; V is O, S, -CH2-, -CH=CH-, or -C=C-; W is CO, COO, CONR1, CSO, CSNR1, SO2, or SO2NR1; m and n independently from each other are 0 to 7 and m+n is 0 to 7, with the proviso that m is not 0 if V is O or S; A1 is H, lower-alkyl, hydroxy-lower-alkyl, or lower-alkenyl; A2 is lower-alkyl, cycloalkyl, cycloalkyl-lower-alkyl, or lower-alkenyl, optionally substituted by R2; A1 and A2 are hydrogen or lower-alkyl; or A1 and A2 or A1 and A3 are bonded to each other to form a ring and -A1-A2- or -A1-A3- are lower-alkylene or lower-alkenylene, optionally substituted by R2, in which one -CH2- group of -A1-A2- or -A1-A3- can optionally be replaced by NR3, S, or O; or A3 and A4 are bonded to each other to form a ring together with the carbon atom to which they are attached and -A3-A4- is -(CH2)2-5- which can optionally be mono- or multiply-substituted by lower-alkyl; A5 is H, lower-alkyl, lower-alkenyl, or aryl-lower-alkyl; A6 is lower-alkyl, cycloalkyl, aryl, aryl-lower-alkyl, heteroaryl, heteroaryl-lower-alkyl, lower-alkoxy-carbonyl-lower-alkyl; R2 is hydroxy, hydroxy-lower-alkyl, lower-alkoxy, lower-alkoxycarbonyl, N(R4,R5), or thio-lower-alkoxy; R1, R3, R4 and R5 independently from each other are hydrogen or lower-alkyl.
Patent NZ-528599-A (NZ)
Title: Ganglioside-associated recombinant antibodies and the use thereof in the diagnosis and treatment of tumors
Inventor: MATEO DE ACOSTA DEL RIO CRISTI
IPC: C12P21/08
Filed: 2002-04-08
Abstract: A chimeric monoclonal antibody derived from the murine antibody MAb P3 that recognizes gangliosides containing N-glycolyated sialic acid wherein the murine monoclonal antibody is produced by the hybridoma cell line with deposit number ECACC 94113026, and wherein the hypervariable domains of the heavy and light chains comprises the following sequences: Heavy chain: CDR1: RYSVH, CDR2: MIWGGGSTDYNSSALKS, CDR3: SGVREGRAQAWFAY Light Chain CDR1: KASQDVSTAVA, CDR2: SASYRYT, CDR3: QQHYSTPWT, is described. Also described is a chimeric monoclonal antibody derived from the murine anti-idiotypic monoclonal antibody 1E10 that recognizes murine MAb P3 wherein the murine monoclonal antibody is produced by the hybridoma cell line with deposit number ECACC 97112901, and wherein the hypervariable domains of the heavy and light chains comprises the following sequences: Heavy chain: CDR1: SYDIN, CDR2: WIFPGDGCTKYNEKFKG, CDR3: EDYYDNSYYFDY Light chain: CDR1: RASQDISNYLN, CDR2: YTSRLHSG, CDR3: QQGNTLPWT. Pharmaceutical compositions comprising the antibodies are useful for the treatment of malignant tumors of breast and melanomas.
Patent NZ-528673-A (NZ)
Title: System and method for enabling the real time buying and selling of electricity generated by fuel cell powered vehicles
Inventor: MCARTHUR GRANT
IPC: B60L11/18
Filed: 2002-03-07
Abstract: A method for utilising a network communication system for enabling the real time buying and selling of electrical power between a fuel cell powered vehicle and a consumer of electricity, wherein the network communication system is adapted to provide real time communication over a network between at lease the fuel cell powered vehicle and the consumer of electricity to facilitate the real time buying and selling of electrical power, comprises: (i) providing connections to the vehicle for the supply of a fuel and for transfer of electricity; (ii) determining the current cost of fuel and price paid for generating electricity using data and information received via the network; (iii) based at least on the cost of fuel and price paid for generating electricity, determining whether to make the fuel cell powered vehicle available for generation of electricity by performing one or more calculations based on data and information received via the network; (iv) controlling the process consumption of fuel by the vehicle and the generation of electricity by the vehicle and the generation of electricity by the vehicle based on the determining at step (iii); and (v) when fuel is consumed by the vehicle and amount of electricity generated by the vehicle, collecting data on the quantity of fuel consumed and amount of electricity generated, calculating the cost of the fuel and the value of the electricity generated, providing a debit charge for the cost of fuel consumed and a credit charge for the value of electricity generated, thereby accounting for fuel consumed and electricity generated by the vehicle.
Patent NZ-529030-A (NZ)
Title: Microprojection array immunization patch and method
Inventor: CORMIER MICHAEL J
IPC: A61M37/00
Filed: 2002-04-22
Abstract: Disclosed are skin patches having a microprojection array, a reservoir (18) containing an antigenic agent and an immune response augmenting adjuvant, and methods of using same to vaccinate animals (e.g., humans) is disclosed. In a preferred embodiment, the microprojection arrays are composed of a photoetched and micro-punched titanium foil (14). The microprojections (12) are coated with a liquid formulation containing a vaccine antigen and an adjuvant such as glucosaminyl muramyl dipeptide, dried, and applied to skin of the animal to be vaccinated using an impact applicator. The microprojections create superficial pathways through the stratum corneum to facilitate permeation of antigenic agent and adjuvant. Antigen dose and depth of penetration can be controlled. This technology has broad applicability for a wide variety of therapeutic vaccines to improve efficacy, and convenience of use.
Patent NZ-530483-A (NZ)
Title: Rights offering and granting
Inventor: WANG XIN
IPC: G06F21/10
Filed: 2002-06-05
Abstract: Processes and systems for offering and granting digital rights that govern distribution and usage of content, services and resources. The processes and systems provide a basis for flexible business models and negotiation transactions between content providers and users. The concept of meta-rights, which permit digital rights to be derived, permits upstream parties in a content distribution chain to dictate rights granted and received by downstream parties. Therefore, each transaction can be considered as a two party transaction between a rights supplier and a rights consumer.
Patent NZ-530682-A (NZ)
Title: Container carrier with sheet of LD polyethylene and single-site catalyzed ethylene-alpha olefin copolymer plastomer
Inventor: WEAVER WILLIAM N
IPC: B65D67/02
Filed: 2004-01-19
Abstract: The carrier has 50 to 99% (wt.) of a low density polyethylene polymer of .91 to .95 gms./cm3 and 1 to 50% (wt.) of a single-site catalyzed ethylene-alpha olefin copolymer plastomer having a density of .85 to .905 gms./cm3.
Patent NZ-535722-A (NZ)
Title: Pressure container with differential vacuum panels
Inventor: MELROSE DAVID MURRAY
Filed: 2004-09-30
Abstract: An improved blow molded plastic container having generally rounded sidewalls that are adapted for hot-fill applications has two adjacent sides and two pairs of controlled deflection panels, each pair reacting to vacuum pressure at differing rates of movement, whereby one pair inverts under vacuum pressure and the other pair remains available for increased "squeezability" or extreme vacuum extraction. The opposing sidewalls are symmetric relative to vacuum panel and rib shape and placement. The ribs and controlled deflection panels cooperate to retain container shape upon filling and cooling and also improves bumper denting resistance, decreases vacuum pressure within the container, and increases light weight capability.
Patent NZ-537051-A (NZ)
Title: Use of bazedoxifene in an extended dosage treatment regimen
Inventor: JENKINS SIMON N
IPC: A61P25/28
Filed: 2003-06-13
Abstract: The disclosure relates to extended dosing regimens for the selective estrogen receptor modulator bazedoxefine (1-[4-(2-azepan-1-yl-ethoxy)-benzyl]-2-(4-hydroxy-phenyl)-3-methyl-1H-indol-5-ol), wherein the medicament comprising bazedoxefine is adapted for administration to a mammal every second days, every third days, every fourth days, every fifth days, every sixth days, or every seventh days (once weekly).
Patent NZ-541541-A (NZ)
Title: A composition suitable for transplantation which comprises a population of hematopoietic stem cells comprising placental stem cells that are CD34+ and CD38-
Inventor: HARIRI ROBERT J
IPC: A61K35/12
Filed: 2002-02-13
Abstract: A composition suitable for transplantation which comprises a population of hematopoietic stem cells comprising placental stem cells that are CD34+ and CD38-, wherein said population is obtained from a human placenta that has been drained of cord blood and perfused to remove residual blood.
Patent NZ-543568-A (NZ)
Title: A valve for flowable material and a closure therefor
Inventor: WRIGLEY ANDREW NICHOLSON
Filed: 2005-11-11
Abstract: A valve for a flowable material. The valve has a body defining a bore defined therein. An opening is defined in the side of the bore for material to flow from the bore, a diaphragm seal sealing the opening. An actuatable member is movable along the bore to control the extent of an uncovered area of the opening defined in the bore to control the flow of material through the opening. The opening allows the actuatable member to protrude therethrough. The diaphragm seal allows the actuatable member to protrude therethrough and is adapted to provide a biasing means for the actuatable member.
Patent NZ-543682-A (NZ)
Title: Wrap surfboard bag
Inventor: WINTER SIMON
Filed: 2005-11-21
Abstract: A flexible carry bag 100 designed to carry one or more sports boards within an elongated enclosure 102. The interior volume 104 of the bag can be selectively increased or decreased to envelop the sportsboard or boards as desired, along with varying amounts of accessories. The bag can be securely closed using an adjustable closure assembly 142 which includes a closure flap 106 that allows for variations in bag volume, and is secured with straps 156.
Patent NZ-544356-A (NZ)
Title: Apparatus for rectifying round pipe and tubing using a plurality of parallel-cylindrical rollers
Inventor: KASTROPIL ANTHONY
IPC: B21C37/30
Filed: 2004-06-01
Abstract: This discloses an apparatus for reducing the diameter, rounding or straightening of pipe or tubing 7 by rolling comprising: (a) a number of closely and equally-spaced, long, narrow, parallel cylindrical rollers 3 in a parallel-cylindrical array, the rollers 3 being rotationally supported in bearing means provided in end flanges of a supporting cylinder, the ends of the rollers 3 being positioned on pitch circles 2 of equal diameter, the bearing means being supported in part-spherical bushings permitting angular displacement of the ends of the rollers 3 relative to the end flanges, and one or both of the end flanges being rotationally displaceable one to the other in the supporting cylinder; (b) apertures in the end flanges permitting the pipe or tubing 7 to advance continuously through the rollers 3 on a path coaxial with the axis of the cylindrical array; (c) means to adjust the relative positions one to the other of the end flanges on the supporting cylinder 1 to skewingly displace the rollers 3 and thereby to displace the central contact zones 6 radially inwards into forceful contact with the external surface of the pipe or tubing 7; (d) bearing means to rotationally support the supporting cylinder; (e) drive means to drive the supporting cylinder 1 in a rotational sense, thereby causing the central contact zones 6 of the rollers 3 to pass over and work upon the external surface of the continuously advancing pipe or tubing 7; (f) sensing means to detect the linear speed of the advancing pipe or tubing 7, the straightness of the pipe or tubing 7, the speed of rotation of the supporting cylinder 1 and the finished diameter of the pipe or tubing 7; (g) control means to control the speed of rotation of the rollers 3 in relation to the speed of advance of the pipe or tubing 7, the height of the support means and the skewing adjustment of the rollers 3; and (h) support means to support the supporting cylinder, the end flanges, the rollers 3, the adjustment means, the bearing means, and the drive means such that the axis of the cylindrical array of the rollers 3 is maintained collinear with the axis of the advancing pipe or tubing 7.
Patent NZ-545780-A (NZ)
Title: Device for cutting and stripping meat
Inventor: FREUND ROBERT
IPC: A22B5/20
Filed: 2004-08-14
Abstract: This discloses a device for cutting and stripping meat 1, comprising a cutting bench that is mounted on a trestle 3 and a circular blade 6 mounted on the bench, turning in a vertical plane around a rotating shaft 12. The depth of cut of the cutting blade is adjustable by a pivoting adjustment 8, where a motor 10 with a flanged gear is connected to the rotating shaft 12 to produce the drive, the motor 10 being positioned laterally above the rotational axle on a pivoting arm 8, which is fixed to the trestle in a discharge zone 2A behind the circular blade 6. The pivoting arm 8 is narrow, in approximate alignment with the circular blade 6 and is mounted on the cutting bench on the trestle by means of a pivot articulation 19 and is fastened by a restricting and/or detachable connection underneath the cutting bench. The pivoting actuator 19 of the pivoting arm is a spindle drive connected in an articulated manner to the pivoting arm, and can be manipulated from the operating side of the cutting bench. A gap wedge is provided in the region between the pivoting arm 8 and the circular blade 6, the wedge being adjusted to produce a narrow gap, thus almost completely filling region.