baber/WOPTO huggingface dataset:
Patent AU-2010200408-C1 (AU)
Title: Fusion constructs and use of same to produce antibodies with increased Fc receptor binding affinity and effector function
Inventor: UMANA PABLO
IPC: A61K38/00
Filed: 2010-02-04
Granted: 2012-11-01
Abstract: The present invention relates to the field of glycosylation engineering of proteins. More particularly, the present invention relates to nucleic acid molecules, including fusion constructs, having catalytic activity and the use of same in glycosylation engineering of host cells to generate polypeptides with improved therapeutic properties, including antibodies with increased Fc receptor binding and increased effector function.
Patent AU-2011325578-C1 (AU)
Title: Pyrazole amide compounds and uses thereof
Inventor: LIU CHANGLING
IPC: A01N43/84
Filed: 2011-11-02
Granted: 2014-05-29
Abstract: Disclosed is a pyrazole amide compound having fungicidal activity, with a structure shown by the general formula (I): each of the substituents of the compound being defined as in the description. The compound of the present invention has fungicidal activity, and excellent prevention and controlling effects on diseases, such as cucumber downy mildew, corn rust, wheat powdery mildew, rice blast, etc., and in particular, a better prevention and controlling effect on cucumber downy mildew and corn rust. Also disclosed is a process for preparing the compound, a fungicidal composition containing the compound of general formula(I)and the use thereof in preventing and controlling disease in crops.
Patent AU-2012214531-C1 (AU)
Title: Antibodies that specifically bind Staphylococcus aureus alpha toxin and methods of use
Inventor: SELLMAN BRET
IPC: C07K16/00
Filed: 2012-02-07
Granted: 2021-07-29
Abstract: The disclosure provides compositions, methods of manufacture and methods of use of antibodies and fragments that bind Staphylococcus aureus alpha toxin. More specifically, the disclosure provides VH CDR and VL CDR region sequences of antibodies or antigen-binding fragments. Method of preventing, treating or managing a condition associated with Staphylococcus aureus infection using the antibodies are also disclosed.
Patent AU-2013332512-C1 (AU)
Title: SHON as a prognostic biomarker for cancer and as a predictor of response to endocrine therapy
Inventor: Liu dong-xu
IPC: C12Q1/68
Filed: 2013-10-17
Granted: 2019-01-03
Abstract: An estrogen-regulated gene sequence SHON has been characterised, and found to be a novel oncogene in mammary carcinoma and significantly associated with estrogen and progesterone receptor expression in breast cancer. The present invention encompasses methods for predicting the responsiveness to endocrine therapy for breast cancer and providing a prognosis for disease-free and/or distant metastasis-free survival of a cancer patient.
Patent AU-2017291794-C1 (AU)
Title: 1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors
Inventor: KEHLER JAN
IPC: C07D471/04
Filed: 2017-06-30
Granted: 2022-01-13
Abstract: The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (I) as PDE1 inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders.
Patent RU-2171753-C1 (RU)
IPC: B60L15/00
Filed: 2000-01-05
Granted: 2001-08-10
Abstract: Изобретение относится к колесным транспортным средствам с тяговыми электрическими приводами, например к инвалидным коляскам, электрокарам и т.п. В транспортном средстве каждый из электроприводов содержит полупроводниковый коммутатор и электромеханический блок, выполненный с исполнительным электродвигателем с возбуждением от постоянных магнитов с дискретно распределенной обмоткой и электромагнитным тормозом с механической защелкой. Имеются пульт управления с задатчиком скорости и направления движения, а также блок управления с узлом логического переключения и управляемым переключателем. В блок управления введены интегратор, выявитель направления вращения ротора исполнительного электродвигателя и элемент временной задержки. При этом обеспечивается торможение транспортного средства как в режиме "электрического арретира", так и с помощью электромагнитного тормоза. Поддержание механического тормоза во взведенном состоянии осуществляется без энергозатрат благодаря применению механической защелки. Транспортное средство характеризуется также повышенной эксплуатационной надежностью. 3 з.п. ф-лы, 3 ил.
Patent RU-2166483-C1 (RU)
Title: Automatic machine for layer loading of thermomold with granular-powder components and servicing conveyer
Inventor: NIKITIN A I
IPC: C03B19/09
Filed: 2000-03-15
Granted: 2001-05-10
Abstract: FIELD: production of material of glass-keramzit type based on crushed glass and used for lining and facing of buildings and structures, floors, etc. SUBSTANCE: automatic machine has a frame on which movably located are slotted pans for components and regulator of blank layers. Automatic machine has mass-distribution grates installed on the frame under slotted pans for contact with them, and servicing conveyer with hoists of thermomolds. Servicing conveyer has guides on which carriage with supports and hoists of thermomolds are installed. The conveyer is provided with vertical guides, platform installed in these guides, brackets fastened along platforms at certain interval. Each hoist has individual adjustment of height of hoisting of thermomold with respect to carriage. Supports for thermomold on carriage are located in compliance with thermomold hoists. EFFECT: increased quality of articles, higher productivity and economic efficiency of production. 2 cl, 5 dwg
Patent RU-2177661-C1 (RU)
Inventor: DVURECHENSKIJ V D
IPC: H01Q11/02
Filed: 2000-08-08
Granted: 2001-12-27
Abstract: FIELD: antenna engineering; transceiver antennas for data transmission radio systems. SUBSTANCE: proposed antenna omnidirectional in azimuth plane is made in the form of two strips 1 and 2 arranged in parallel planes. Width Δ 1  and Δ 2  of first and second strips 1 and 2, respectively, varies along antenna obeying quasi-periodic law. Strips are displaced relative to each other through half-cycle along antenna. EFFECT: enhanced gain of antenna. 4 cl, 1 dwg
Patent RU-2180243-C1 (RU)
Title: Method for draining bile ducts and device to take out string from bile ducts
Inventor: LOBAKOV A I
IPC: A61M25/01
Filed: 2000-08-17
Granted: 2002-03-10
Abstract: FIELD: medicine. SUBSTANCE: method involves making cholangiography under radiological control, conducting string through endoscope canal in retrograde way through the major duodenal papilla into the bile ducts beyond the stenosis zone into the proximal segments of extrahepatic bile ducts. The stent is set using the string and the string is removed. The working end if the string is taken outside in transcutaneous and transhepatic way. The string is stretched holding both ends and then the stent is set. The device has hollow needle having piston telescopically mounted inside. The ends of the needle and piston are beveled. The needle tip has notch shaped as hook 2-3 mm distant from the end on one side. The other needle end has coupling member. The coupling member has mark coaxial with the notch. Piston end has flange fixably mounted on the coupling member. EFFECT: reduced risk of traumatic complications; accelerated patient recovery after surgical operation. 2 cl, 2 dwg
Patent RU-2183100-C1 (RU)
Title: Method and fixing device for cutting tissues in performing endosurgical interventions
Inventor: BONDARENKO V O
IPC: A61B17/00
Filed: 2001-08-10
Granted: 2002-06-10
Abstract: FIELD: medicine. SUBSTANCE: device has working part manufactured as suction member and flexible tube. Tube is connected to the suction member through an additional tube and to excessive pressure source. The additional tube is manufactured as handle and/or coupling means for making connection to surgical equipment. The suction member is manufactured from latex. It has size of maximum cross-section that is greater than additional tube maximum cross-section at least by 1/3. The fixing device is usable for fixing tissues in performing tissue dissection. Rarefaction is created between the tissues and the nozzle. Tissue traction and anti-traction is created by using the handle. After transecting and/or moving tissues apart, the rarefaction is taken off. EFFECT: high reliability in fixing tissues. 5 cl
Patent RU-2192226-C1 (RU)
Inventor: MOROZ Z I
IPC: A61F9/007
Filed: 2001-09-06
Granted: 2002-11-10
Abstract: Изобретение относится к медицине, а именно к офтальмохирургии, и предназначено для прогнозирования развития асептического некроза бельма после второго этапа кератопротезирования. Определяют суммарную тактильную чувствительность бельма (ТБЧ) до операции и среднюю суммарную ТБЧ перед вторым этапом протезирования в 17 точках эстезиометром с дозированным давлением на площадь поверхности, при этом ТБЧ вычисляют по формуле Т=(400 мг/см 2 )/Р, где Т - тактильная чувствительности бельма в точке, Р - дозированное давление 50, 100, 200 или 400 мг/см 2  (400 мг/см 2  - максимальное дозированное давление), и при снижении в 2 и более раза средней суммарной ТБЧ перед вторым этапом кератопротезирования по сравнению с суммарной ТБЧ перед операцией прогнозируют развитие асептического некроза бельма после второго этапа кератопротезирования. Способ позволяет своевременно выявить нарушения трофики поверхностных слоев бельма над опорной пластинкой кератопротеза до появления клинических признаков асептического некроза бельма. 3 табл.
Patent RU-2189446-C1 (RU)
Inventor: KOSTYLEV A D
IPC: E21D15/44
Filed: 2001-10-19
Granted: 2002-09-20
Abstract: FIELD: mining; applicable in mines prone to rock bursts. SUBSTANCE: hydraulic prop includes cylinder, rod with piston, shock absorber installed under rod, valve, slide valve with steps and shank with flange, slide valve body with discharge hole in its wall and vertical guides and connected to cylinder, spring located on slide valve shank between slide valve body and shank flange, weight with stop located in vertical guides of slide valve body and engageable by its lower end with slide valve step, branch pipe communicating cylinder cavities with a cavity of slide valve body, and additional branch pipes connected to cylinder lower part of its above-piston cavity, with spaces between them in height and connected to slide valve body along its length. In initial state of hydraulic prop, holes of branch pipes in slide valve body are overlapped by slide valve made with steps and provided with stepped rack having longitudinal slot for receiving of weight stop having belt whose diameter is larger than width of stepped rack longitudinal slot. Stepped rack is installed in a spaced relation to slide valve steps for disengagement of weight stop from next slide valve step in every burst. EFFECT: higher reliability of protection of hydraulic prop from damage during repeated rock bursts due to discharge of definite amount of fluid from prop cylinder in every rock burst. 3 dwg
Patent RU-2204860-C1 (RU)
Title: Functional driver
Inventor: ANDREEV D V
IPC: G06G7/25
Filed: 2001-10-23
Granted: 2003-05-20
Abstract: FIELD: automatic control and analog computer engineering. SUBSTANCE: device that can be used for building functional assemblies of analog computers, automatic monitoring and control means, and analog processors provides for reproducing rejection or selective filter function, or function of base or peak clipper of analog signal. Device has two comparators, four Boolean EXCLUSIVE OR gates, two making and two breaking switches. EFFECT: enlarged functional capabilities. 1 cl, 2 dwg
Patent RU-2205400-C1 (RU)
Title: Chromatographic polycapillary column
Inventor: SIDEL NIKOV V N
IPC: G01N30/60
Filed: 2002-03-18
Granted: 2003-05-27
Abstract: FIELD: chromatography, polycapillary chromatographic columns of high-speed chromatography, in particular. SUBSTANCE: chromatographic polycapillary column comes in the form of monolithic bar pierced by system of capillaries which internal surface is coated with layer of holding matter. Monolithic bar is U-shaped and comprises three elements. Capillaries of first and third elements are parallel to longitudinal axis of bar. Capillaries of second element positioned between first and third elements are twisted along longitudinal symmetry axis of bar and are so bent that inlet and outlet butts of column are located at distance of diameter of bend. Besides this capillaries of second element are twisted along longitudinal symmetry axis uniformly over its length through number of turns over 0.5. Bending radius of second element is more than 1.0 cm. EFFECT: development of chromatographic column in which inlet and outlet butts are at minimal distance one from another and which exhibits small overall dimensions without deterioration of its separation properties and efficiency. 3 cl, 2 dwg
Patent RU-2218892-C1 (RU)
Inventor: KARLOV A V
IPC: A61B17/66
Filed: 2002-04-15
Granted: 2003-12-20
Abstract: FIELD: medical engineering. SUBSTANCE: device has two frames each having two arches connected to each other with threaded tie rods. Units for fastening perosseous threaded rods are mounted on threaded tie rods. Rotation unit and reposition unit are mounted between two frames. Device for measuring dynamometric load is mounted on the lower frame. A unit for fastening perosseous threaded rods has holders fixed on threaded tie rod. The holders are designed as rectangles with openings and deviated orthogonal radial sampler equal to one half of perosseous threaded rod diameter. One holder has threaded hole and screws over threaded tie rod. Another holder has smooth hole and is put on threaded tie rod having one end shaped as quadrate on the length of 5 mm. The holders are on threaded tie rod are additionally fastened with nuts on both sides, producing self- tightening effect. EFFECT: simplified and reliable design. 2 dwg
Patent RU-2210265-C1 (RU)
IPC: A23L13/70
Filed: 2002-06-13
Granted: 2003-08-20
Abstract: FIELD: meat industry. SUBSTANCE: method involves separating raw meat in the form of ham flesh with 2-cm thick subcutaneous fat layer separated from hip part of hog half carcasses with skin, or free of skin, or with partly removed skin; preparing salt brine with the use of edible salt, sodium nitrite and phosphate-containing preparation; salting raw meat by means of multiple-needle injector, with temperature inside raw meat and temperature of salt brine at injector needle outlet openings being equal to one another or differing by no more than 1 C at temperature range of 1-4 C; massaging in vacuum massaging apparatus for 12-16 hours at rotational speed of massaging apparatus drum of 6-8 rev/min in cyclic mode including mechanical action for 18-22 min and standing for 35-45 min in each cycle, with temperature of raw meat at the end of massaging process being not in the excess of 6 C; discharging raw meat from vacuum massaging apparatus and providing maturation holding at temperature of 0-4 C for about 48 hours; molding raw meat by laying ham in nets; providing thermal processing in hermetically sealed thermal chamber including succession of operations: slight drying with hot air having temperature of 55-60 C for 30-35 min, cooking by means of air-steam mixture at temperature of 70-75 C and relative humidity of 98-99%; providing air cooling until temperature inside ham is 6-8 C. EFFECT: improved structural-mechanical and functional-processing properties of raw meat and, accordingly, improved quality and biological value of finished product, and reduced production cost. 9 cl, 1 tbl, 2 ex
Patent RU-2216133-C1 (RU)
Title: Low-voltage gas and air plasma generator
Inventor: SHESTAKOV A I
IPC: H05H1/26
Filed: 2002-07-16
Granted: 2003-11-10
Abstract: FIELD: plasma technology, coat spraying, plasma welding. SUBSTANCE: spun gas and air flow goes out fro cathode unit and enters anode unit, to zone of arc lashing. Zone of arc lashing comes in the form of cone located between two cylindrical conduits, inlet and outlet. Insert with forming conduit which diameter is smaller than outlet conduit by factor of 1.2-6.0 enters outlet conduit. Technical result of invention consists in decrease of operating voltage to 100-120 V in arc at high flow rate of gas and air mixture ( to 9.0 cu m/h ) and strength of current to 120-200 A. Coats sprayed under supersonic mode in manual deposition are distinguished by high density displaying porosity under 1% with utilization factor up to 80%. EFFECT: high density of sprayed coats. 1 cl, 3 dwg, 1 tbl
Patent RU-2229913-C1 (RU)
Inventor: EFIMOV K M
IPC: A62D3/35
Filed: 2003-01-20
Granted: 2004-06-10
Abstract: FIELD: toxic materials technology. SUBSTANCE: method comprises hydrolysis to form hydrolyzate, which is treated with calcium hydroxide and then with 30-50% ferrous or ferric sulfate solution. Thus treated hydrolyzate is calcined at 300-350 o  for 1.5-2 h until destruction of covalent carbon-phosphorus bonds is completed so forming harmless water-insoluble precipitate containing no compounds with covalent carbon-phosphorus bonds. EFFECT: reduced power consumption. 2 cl, 1 tbl, 2 ex
Patent RU-2238447-C1 (RU)
Inventor: BONAZOLI STIVEN
IPC: F16C33/10
Filed: 2003-01-22
Granted: 2004-10-20
Abstract: FIELD: mechanical engineering. 
     SUBSTANCE: insert has cylindrical wall with inner load-carrying surface, the shape and sizes of which are chosen so that it embraces the surface of the pin of the shaft in the rolling mill. The load-carrying surface has the primary groove for receiving oil which is a lubricant between the pin and carrying surface. 
     EFFECT: enhanced quality of working. 
     8 cl, 7 dwg
Patent RU-2225713-C1 (RU)
Title: Pharmaceutical composition eliciting anti-anginal, anti-ischemic and nootropic effect
IPC: A61K31/513
Filed: 2003-03-19
Granted: 2004-03-20
Abstract: FIELD: medicine, pharmacy. SUBSTANCE: invention relates to the development of pharmaceutical composition with broad spectrum of pharmacological effect based on derivatives of orotic acid. Invention proposes the composition containing a mixture of potassium orotate and magnesium orotate taken in the definite ratio and accessory substances also and this composition can be used as capsules, dragee or tablets. Invention expands assortment of drugs used in treatment of ischemic heart disease being without any adverse effects. EFFECT: valuable medicinal properties of composition. 3 cl, 2 ex
Patent RU-2237572-C1 (RU)
Inventor: SHEVTSOV V V
IPC: B26B19/24
Filed: 2003-04-21
Granted: 2004-10-10
Abstract: FIELD: animal husbandry. 
     SUBSTANCE: device has housing, driving mechanism, lever, movable knife, unmovable comb, and pressing mechanism. The pressing mechanism is made of vertically mounted thrust rod. One end of the rod is screwed in the housing, and the other abuts against the plate. The bottom plate bears on three roller bearings set in the separator on the boss. The boss, lever, and roller bearings are set in reciprocation. The front bearings are arranged so that their vertical axes do not reach the axis of the thrust rod when the lever is at end positions. 
     EFFECT: improved quality of shearing. 
     2 dwg
Patent RU-2243860-C1 (RU)
Title: Method of control over machining
Inventor: MIKHAJLOV S V
IPC: B23B1/00
Filed: 2003-05-26
Granted: 2005-01-10
Abstract: FIELD: metals machining. 
     SUBSTANCE: the invention is dealt with the field of metals machining. The technical result is an increased reliability and accuracy of determination of optimal conditions of machining. The invention provides for a shooting in infra-red range of frequency of a zone of cutting by an infrared imager installed over the cutting tool with a consequent analysis infra-red image plotting of geometrical characteristics of a cut chip with the purpose to determine a degree of their correspondence to the optimal values. In the case of fluctuation of the controlled magnitudes from the reference values a corresponding parameter of a cutting mode is changed. With the purpose to increase stability and qualities of machining the control of cutting is exercised depending on the value of the range of change of geometrical parameters of a zone the infra-red image plotting of the chip during machining with constant modes. 
     EFFECT: the invention ensures increased reliability and accuracy of determination of optimal conditions of machining. 
     1 dwg
Patent RU-2238827-C1 (RU)
Inventor: BRUNOV O G
IPC: B23K9/095
Filed: 2003-07-10
Granted: 2004-10-27
Abstract: FIELD: mechanical engineering; welding. 
     SUBSTANCE: invention relates to methods of control of process equipment providing impulse feeding of welding wire to welding zone. Method includes automatic supply of signal to control system of mechanism providing inpulse feeding of welding wire and furnished with control signal generating source for which purpose welding current recording unit is used. Welding wire feed impulse is generated at moment when minimum welding current value becomes equal to preset value. 
     EFFECT: provision of control of size of size of molten metal in welding at impulse feeding of welding wire. 
     1 dwg
Patent RU-2236875-C1 (RU)
Title: Система пожаротушения в стволе мусоропровода многоэтажного здания
Inventor: STAROSTIN M M
IPC: A62C2/18
Filed: 2003-08-14
Granted: 2004-09-27
Abstract: Система пожаротушения в стволе мусоропровода многоэтажного здания. Данная система пожаротушения позволяет предотвратить попадание дыма в жилые помещения при возгорании внутри ствола мусоропровода. Система пожаротушения в стволе мусоропровода многоэтажного здания содержит устройство, автоматически обеспечивающее подачу гасящей жидкости в ствол мусоропровода при возгорании и автоматическое отключение ее при локализации возгорания, клапаны мусоропровода. Система пожаротушения снабжена запорным устройством, расположенным в стволе мусоропровода, выполненным в виде трубы с вырезами, обеспечивающими поступление мусора через клапаны мусоропровода, с возможностью перекрытия клапанов мусоропровода при возгорании в стволе мусоропровода, стопорным устройством и механизмом возвращения запорного устройства в исходное положение. В верхней части ствола мусоропровода установлен дефлектор. В нижней части ствола мусоропровода установлены шибера с автоматикой локализации возгорания. 2 з.п. ф-лы, 2 ил.
Patent RU-2253481-C1 (RU)
Title: Дезинфицирующая салфетка (варианты)
Inventor: JUZBASHEV V G
IPC: A61L2/18
Filed: 2003-11-03
Granted: 2005-06-10
Abstract: Изобретение относится к медицине. Салфетка используется при дезинфицирующей обработке рук, поверхностей, инъекционного поля или кожи локтевого сгиба доноров. Дезинфицирующая салфетка, выполненная из впитывающего материала и пропитанная жидким дезинфицирующим составом, имеет размер (135-145) мм × (165-175) мм. Она выполнена из материала, состоящего из вискозы, полистера или смеси вискозы с полистером. Толщина материала, из которого изготовлена салфетка, 25-35 г/м 2 , его впитывающая способность 9,5-10,0 г/г. Для пропитки салфетки использовано 4,0-5,0 мл жидкого дезинфицирующего состава, включающий алкилдиметилбензиламмоний хлорид, алкилдиметил(этилбензил)аммоний хлорид, глицерин, спирт этиловый и воду при определенном соотношении ингредиентов. Второй вариант салфетки размером (55-65) мм × (71-81) мм выполнен из материала толщиной 55-65 г/м 2 , его впитывающая способность 10,5-11,5 г/г. Для пропитки салфетки использовано 1,0-2,0 мл жидкого дезинфицирующего состава. Изобретение позволяет снизить загрязнения окружающей среды отработанным материалом, снизить себестоимость, упростить технологию изготовления и повысить эффективность. 2 н. и 5 з.п. ф-лы.
Patent RU-2261800-C1 (RU)
Inventor: JANKOV V P
IPC: B29C53/56
Filed: 2004-01-30
Granted: 2005-10-10
Abstract: FIELD: mechanical engineering. 
     SUBSTANCE: method comprises laying inner load-bearing layer to define the rectangular corrugation on it, racks of rectangular cross-section, and multilayer load-bearing shell.  Between the inner load-bearing layer with racks and load-bearing shell is the flexible glue layer with no less than 40% elongation for deformations within the flexible shearing deformation of the corrugation with racks with respect to the load-bearing shell. 
     EFFECT: enhanced reliability. 
     5 cl, 7 dwg