baber/WOPTO huggingface dataset:
Patent IL-109619-A (IL)
Title: Conjugation-stabilized polypeptide compositions and therapeutic and diagnostic formulations comprising same
IPC: A61K38/095
Filed: 1994-05-11
Abstract: A stabilized conjugated peptide complex comprising a peptide conjugatively coupled to a polymer including lipophilic and hydrophilic moieties, wherein the peptide may be insulin, calcitonin, or an enzyme. In a particular aspect, the invention comprises an insulin composition suitable for parenteral, as well as non-parenteral administration, comprising insulin covalently coupled with a polymer including a linear polyalkylene glycol moiety and a lipophilic moiety, wherein the insulin, the linear polyalkylene glycol moiety and the lipophilic moiety are conformationally arranged in relation to one another such that the insulin in the composition has an enhanced in vivo resistance to enzymatic degradation, relative to insulin alone. The conjugates of the invention are usefully employed in therapeutic as well as non-therapeutic, or diagnostic, applications as shown in the figure.
Patent IL-121066-A (IL)
Title: Process for the preparation of 5-bromo-2-fluorobenzeneboronic acid
IPC: B01J27/122
Filed: 1997-06-12
Abstract: A process is disclosed for the preparation of 5-bromo-2-fluorobenzeneboronic acid, which is useful as an intermediate in the preparation of a non-ester pyrethroid compound. The compound can be, for example, a fluoroolefin, which is useful as a pesticide.
Patent IL-123113-A (IL)
Title: Hand-held agricultural machine
IPC: A01D46/26
Filed: 1998-01-29
Abstract: A hand-held agricultural machine (20) comprising a vibrating rod (44) having a longitudinal axis and fitted at a free end thereof with an agricultural accessory member (46) and being engaged at an opposed end thereof to a motion generator (22) imparting said vibrating rod a reciprocal-linear motion along said longitudinal axis, at a predetermined frequency and amplitude; and an elongate support member (26) connected to said motion generator and extending along said longitudinal axis.
Patent IL-123253-A (IL)
Title: Ct cone beam image reconstruction with circle and line scan path
IPC: G01N23/04
Filed: 1997-06-23
Abstract: In an imaging system wherein a source of cone beam radiation and a detector array are mounted for movement with respect to an object, a method for reconstructing an image of said object comprising the steps of: establishing relative movement between said cone beam source and said object along a scan path comprising circular and linear components; operating said cone beam source to irradiate said object during such movement to project cone beam data onto said detector array, said projected data comprising linear and circular data sets which respectively correspond to the linear and circular components of said scan path; selecting a subset of data elements from said linear data set, each of said selected data elements being associated with a specified set of spatial parameters; applying a Radon transform to each of said data elements in said selected subset to provide a first set of image reconstruction data; selectively processing each of the data elements in the circular data set to provide a second set of image reconstruction data which collectively represents all the data elements in said circular data set; and combining said first and second sets of image reconstruction data to provide an image of said object. 3124 ח' בטבת התשס" ב - December 23, 2001
Patent IL-123990-A (IL)
Title: Process for the preparation of 3-bromoanisole from nitrobenzene
Inventor: GELMONT MARK
IPC: C07C43/225
Filed: 1998-04-07
Abstract: Process for the preparation of 3-bromoanisole comprising methoxydenitrating 3-bromonitrobenzene in the presence of a phase-transfer catalyst (PTC), and the preparation of 3-bromonirtobenzene by the bromination of nitrobenzene with bromine in oleum. The methoxydenitration reagent in an alkali metal methoxide, which is selected from sodium methoxide and potassium methoxide. The amount of methoxide used is 1-1.5 mol per mol of 3-bromonitrobenzene. The alkali methoxide can be a pre-prepared solid or it can be prepared in situ, by the reaction of the corresponding alkali hydroxide and methanol. In the case when pre-prepared solid methoxide is used, the effective amount of alkali hydroxide is between 1.2-1.7 mol per mol of 3-bromonitrobenzebe. The reaction temperatures are between about 40 to 80° C., with preference to reaction temperatures of 50 to 55° C. In the case in which methoxide is prepared in situ, the effective amount of alkali hydroxide is between 2.2-2.4 mol per mol of 3-bromonitrobenzene. The reaction temperatures are between about 50 to 80° C. with preference to reaction temperatures of 55 to 65° C.
Patent IL-127266-A (IL)
Title: Stable, non-hygroscopic mucate salts of l(-) carnitine and alkanoyl l(-) carnitines, a process for their preparation and solid, orally administrable compositions containing such salts
IPC: C07C227/18
Filed: 1997-05-26
Abstract: PCT No. PCT/EP97/02693 Sec. 371 Date Nov. 30, 1998 Sec. 102(e) Date Nov. 30, 1998 PCT Filed May 26, 1997 PCT Pub. No. WO97/46512 PCT Pub. Date Dec. 11, 1997Stable, non-hygroscopic salts of L(-)carnitine and alkanoyl L(-)carnitines with mucic acid of formula (I) are disclosed wherein the molar ratio between the carnitine moiety and mucic acid is 2:1. A process for producing the salts and solid orally administrable compositions containing same are also disclosed.
Patent IL-131218-A (IL)
Title: Vehicle safety system
IPC: B60R21/26
Filed: 1998-09-16
Abstract: A restraint system for protecting vehicle passengers during a crash event comprising: (a) a vehicle seat including a substructure frame attached to the vehicle; (b) a safety belt (25) having a first non- extensible part (26) and a second extensible part (27), wherein one end of each belt part is attached to the vehicle seat substructure for extension from the points of attachment to the substructure frame across a passenger's lap; (c) fastening structures on ends of the belt parts non-attached to the substructure for uniting the parts over the passenger's lap; (d) an inflatable member (17) mounted on the non-extensible part of the belt on that side facing away from the passenger's lap; (d) belt position orienting means operatively associated with the non- extensible belt part for maintaining the inflatable member mounted thereon facing away from the passenger's lap; (f) a restraint system battery power supply (11) which is independent of any other vehicle power source; (g) an electrical switching combination contained in the belt part fastening structures that permit activation of the inflatable member only when the inflatable member is positioned facing away from the passenger's lap; (h) a source of inflating gas (15, 16) operably joined to the inflatable member; (i) a crash event sensor (12), and (j) system electronics (13) mounted on the seat substructure frame for electrically interconnecting the crash event sensor, the source of inflating gas, the battery power supply and the electrical switching combination. 1971 ט" ז באב התשס" ב - July 25, 2002
Patent IL-144847-A (IL)
Title: Combinations for the treatment of diseases involving angiogenesis
IPC: A61P17/06
Filed: 2001-08-09
Abstract: Compositions for the inhibition of the formation of new vasculature by angiogenesis are provided comprising the combination of a vasculature damaging agent and an inhibitor of the formation or action of nitric oxide in mammalian systems. There are also provided the use of said combinations in medicaments and kits of said compounds and treatment employing said materials.
Patent IL-146328-A (IL)
Title: Antiblock talc compositions and polyolefins containing them
IPC: C08J5/18
Filed: 2001-11-04
Abstract: The present invention relates to a product, a process for its preparation and the use of such in plastic film production. More specifically, the present invention relates to an antiblock talc, a process for the preparation of such and its use as an additive in the production of polyolefin film. <??>Polyolefin films produced according to the process of the present invention are useful in a broad range of packaging and film covering applications.
Patent IL-147905-A (IL)
Title: Salt water desalination process using ion selective membranes
IPC: B01D1/26
Filed: 2000-08-16
Abstract: The invention is directed to an improved desalination process to produce potable water. The process represents an improvement of hybrid of membrane and desalination technologies. The improvement of the invention comprises the operation of an ion selective membrane at a variable pressure as a function of the cost of electricity to form a softened salt water that is blended in variable proportions, to increase the top operating temperature of the desalination system and increase recovery of potable water, with untreated salt water.
Patent IL-152315-A (IL)
Title: Soluble ctla4 mutant molecules and pharmaceutical compositions containing the same
IPC: C07K14/705
Filed: 2001-05-23
Abstract: The present invention provides soluble CTLA4 mutant molecules which bind with greater avidity to the CD80 and/or CD86 antigen than wild type CTLA4 or non-mutated CTLA4Ig. The soluble CTLA4 molecules have a first amino acid sequence comprising the extracellular domain of CTLA4, where certain amino acid residues within the S25-R33 region and M97-G107 region are mutated. The mutant molecules of the invention may also include a second amino acid sequence which increases the solubility of the mutant molecule.
Patent IL-153733-A (IL)
Title: Use of deferiprone for the preparation of iron chelating agents
IPC: A61K31/44
Filed: 2002-12-29
Abstract: A method of treating iron induced cardiac disease in a patient with iron overload, such as in thalassemia or the like comprising administering to the patient a therapeutically effective amount of deferiprone or a physiologically acceptable salt thereof sufficient to treat induced cardiac disease normally associated with iron overload.
Patent IL-163774-A (IL)
Title: Combinations comprising epothilone derivatives and alkylating agents and pharmaceutical compositions comprising them
IPC: A61P43/00
Filed: 2004-08-26
Abstract: The invention relates to a pharmaceutical combination which comprises (a) an alkylating agent and (b) an epothilone derivative of formula (I) wherein A represents O or NRN, wherein RN is hydrogen or lower alkyl, R is hydrogen or lower alkyl, and Z is O or a bond. Said combination can be useful for the treatment of a proliferative disease, especially a tumor disease.
Patent IL-168349-A (IL)
Title: Copolymers of ethylene with alpha-olefins
IPC: C08L23/08
Filed: 2005-05-03
Abstract: Copolymers of ethylene with alpha-olefins which have a molar mass distribution Mw/Mn of from 1 to 8, a density of from 0.85 to 0.94 g/cm3, a molar mass Mn of from 10.000 g/mol to 4 000 000 g/mol and a CDBI of less than 50% and in which the side chain branching of the maxima of the individual peaks of the short chain branching distribution is in each case greater than 5 CH3/1 000 carbon atoms, a process for preparing them, a catalyst suitable for preparing them and fibers, moldings, films or polymer mixtures in which these copolymers are present.
Patent IL-176898-A (IL)
Title: Growth factor-binding compounds, compositions comprising them and uses thereof in the manufacture of pharmaceutical compositions
IPC: A61K47/48
Filed: 2006-07-17
Abstract: Growth factor binding compounds having a plurality of acyclic isophthalic acid groups attached to a non-peptide organic scaffold and pharmaceutical compositions of the same are disclosed. Methods of administering and using the growth factor binding compounds or the growth factor binding compositions are also taught. These novel growth factor binding compounds are useful for treating angiogenesis, excessive cellular proliferation, tumor growth, and a combination thereof as well as inhibiting growth factor binding to cells and phosphorylation.
Patent IL-178248-A (IL)
Title: Gastrostomy tube extension device
IPC: A61M25/02
Filed: 2006-09-21
Abstract: A gastrostomy tube extension device which can facilitate insertion or removal of a gastrostomy tube by making the degree of extension of the gastrostomy tube constant. A gastrostomy tube extension device used for inserting and taking out a gastrostomy tube into/from a hole formed on a patient's abdomen, the gastrostomy tube including an outer fixing member to be installed on the skin surface side, an inner fixing member installed on the inner surface side of the stomach wall, and a tube member for connecting the outer fixing member and the inner fixing member and the gastrostomy tube extension device comprising a rod and an engaging member. The rod has a rod-shaped member which can push the center of the distal end of the inner fixing member with its distal portion toward the distal end, and with a plurality of engaging step portions formed on the proximal portion. The engaging member is also provided with a lower engaging portion which can engage with an outer fixing member and an upper engaging portion which can engage one of the engaging step portions of the rod.
Patent IL-179684-A (IL)
Title: Combinations comprising antimuscarinic agents and corticosteroids
IPC: A61K31/573
Filed: 2006-11-29
Abstract: Combination (I) comprises a phosphodiesterase inhibitor 4 (PDE4) (A) and an antagonist of M3 muscarinic receptors (B) (3(R)-(2-hydroxy-2, 2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicyclo [2.2.2] octane), in the form of a salt having an anion X (anion of a mono or polyvalent acid). An independent claim is also included for a method of treating a patient suffering from or susceptible to a respiratory disease or condition which responds to M3 antagonism comprising simultaneous, concurrent, separate or sequential administration of (I). - ACTIVITY : Antiasthmatic; Respiratory-Gen.; Antiinflammatory. - MECHANISM OF ACTION : Phosphodiesterase-4 inhibitor; Muscarinic receptors antagonist; Leukotriene-D4 antagonist; Neurokinin-1- receptor antagonist; Epidermal growth factor receptor kinase inhibitor; Beta-2 agonist; p38 Kinase inhibitor.
Patent IL-187093-A (IL)
Title: Power-driven wheel for a military vehicle
Filed: 2007-11-01
Abstract: The invention relates to a power-driven wheel (1) having an axis (A) and comprising an axial-flow motor (4) coaxial with said axis (A), a casing (5) housing said motor (4), and a tubular hub (2) connected funtionally to said motor (4). In order to facilitate repairs, said casing (5) comprises a housing (6) with an open axial end (14) defining a seat for said motor (4), and an end member (8) releasable engaging said open axial end (14) of said housing (6) to grip said motor (4) inside said casing (5). The wheel (1) is connectable to a frame (45) of a vehicle by 
connecting means (43) interposed between said wheel (1) and said frame (45) so that, when said end member (8) is removed from said housing (6), said motor (4) can be withdrawn completely through said open axial end (14).
Patent IL-194994-A (IL)
Title: N ,n' - bis(2, 3 - butadienyl) - 1, 4 - butanediamine for use in the treatment of prostate cancer in a male animal
IPC: A61K/
Filed: 2008-10-30
Abstract: N1,N4-bis(buta-1,3-dienyl)butane-1,4-diamine dihydrochloride (also referred to as MDL 72,527 and N,N'-di-2,3-butadienyl-1,4-butanediamine dihydrochloride), or salts or solvates thereof, its use as an antioxidant, its use in preventing and/or treating prostate cancer in male humans, and its use in reducing the concentration of reactive oxygen species in human prostate gland tissue or any other body tissue, and methods of making the compound thereof. Other methods include inhibiting acetyl polyamine oxidase in human prostate tissue or other human body tissue comprising administering a therapeutic amount of N,N'-bis(2,3-butadienyl)-1,4-butanediamine or a salt or solvate thereof to the human, and a method of determining oxidative stress in human prostate tissue or other human or animal body tissue comprising measuring a ratio of oxidized 2',7'-dichlorodihydrofluorescein diacetate fluorescence:DNA fluorescence and hydroethidine dye fluorescence ex vivo or in vivo.
Patent IL-210333-A (IL)
Title: Dual-temperature energy storage tank
Inventor: PEREZ JESUS MARIA LATA
IPC: F28D/
Filed: 2010-12-29
Abstract: A thermocline storage tank (2) is presented, which includes a barrier member (13) that floats between the two fluids (3,4) stored at different temperatures, physically separating and insulating them. The floating barrier (13) includes a number of design features that broaden its application scope, enabling it for use in fields like thermal storage systems of solar power plants.
Patent IL-218504-A (IL)
Title: Lkktet and/or lkktnt peptides for treatment of dry eye syndrome
Inventor: CROCKFORD DAVID
IPC: A61K38/08
Filed: 2012-03-06
Abstract: A composition including a peptide agent including amino acid sequence LKKTET [SEQ ID NO: 1] or LKKTNT [SEQ ID NO: 2], a conservative variant thereof, or a stimulating agent that stimulates production of an LKKTET [SEQ ID NO: 1] or LKKTNT [SEQ ID NO: 2] peptide, or a conservative variant thereof, the composition including at least one amino acid stabilizing agent or lyophilization bulking agent, the composition being in lyophilized form, or in a form capable of being lyophilized.
Patent JP-S5325803-A (JP)
Title: Coil dismantling method in core of rotary machine
Inventor: NAKAYAMA KAZUAKI
IPC: H02K15/00
Filed: 1976-08-24
Abstract: PURPOSE: To dismantle a coil without secondary damage by cutting off wedges and insulator at the upper side of the coil, pulling out the component wire of the coil, and then pulling out the insulator. 
     COPYRIGHT: (C)1978,JPO&Japio
Patent JP-H09286624-A (JP)
Title: Die for forming optical element
Inventor: IGUCHI HIROAKI
IPC: C03B40/02
Filed: 1996-04-22
Abstract: PROBLEM TO BE SOLVED: To obtain a die for forming an optical element capable of giving a high strength and high precision specular surface and hardly causing a fusion reaction with stock to be formed. SOLUTION: A 1st middle layer 2, a 2nd middle layer 3 and a top layer 4 are successively formed on the forming surface of a die substrate 1 made of an SiC sintered compact. The 1st middle layer 2 is an SiC layer, the 2nd middle layer 3 is a layer of at least one kind of metallic nitride selected from among TiN, AlN, ZrN, TaN and TiAlN and the top layer 4 is a Pt layer formed on the 2nd middle layer 3 and recrystallized in high vacuum.
Patent JP-H01273756-A (JP)
Title: Parking brake
Inventor: MORITA MASAYUKI
IPC: B60T7/12
Filed: 1988-04-25
Abstract: PURPOSE:To park with brake force working properly by actuating a wire tension means by inputting both a parking signal and car speed zero signal and locking the wire tension means by a lock means when a load detector detects the specified load. CONSTITUTION:When both of the parking signal from a parking signal generating means 1 and the car speed zero signal from a speed detector 2 are input, a control circuit 7 actuates a wire tension means 3 for pulling a wire resulting in the actuation of a parking brake. At this moment, when a signal having enough value to apply parking brake properly from a load detector 4 is input, the actuation of the wire tension means 3 is locked as it is by a locking means 5. In the next step when a non-parking signal is output from a non-parking signal generating means 6, the lock of the wire tension means 3 is canceled resulting in the release of the parking brake. Thus, a car can be parked with parking force worked properly, and the life of a wire can be prolonged.
Patent JP-S61259200-A (JP)
Inventor: KURIHARA MIKIO
IPC: B01D53/04
Filed: 1985-05-14
Abstract: (57)【要約】本公報は電子出願前の出願データであるた め要約のデータは記録されません。
Patent JP-H05275902-A (JP)
Title: Strip conductor high frequency circuit element
IPC: H03H7/075
Filed: 1992-03-25
Abstract: PURPOSE:To improve the frequency characteristic of a conductor high frequency circuit element without using any substrate of a special material. CONSTITUTION:The strip conductor high frequency circuit element consists of a 1st substrate 10 containing an earth conductor 11 on its surface, a 2nd substrate 30 containing a strip conductor 31 forming a circuit on its surface, and a holding means which holds both substrates 10 and 30 with a space secured between them so that the surfaces containing the conductors 11 and 31 respectively are set opposite to each other with a minute gap secured between them. As a minute gap is secured between both conductors 11 and 31 set opposite to each other, such circuit elements like the inductance, the capacitance, etc., are obtained in a semi-microwave area having the satisfactory characteristic owing to both conductors 11 and 31 and the air existing between these conductors.
Patent JP-S5435581-A (JP)
Title: Shielding plug
Inventor: UGAWA YUKIO
IPC: G21C13/06
Filed: 1977-08-24
Abstract: PURPOSE: To improve coefficient of overall heat transmission, by fitting a heat shielding plate at a bottom of a shielding plug through a support metal, being separated from a drum plate of the shielding plug. 
     COPYRIGHT: (C)1979,JPO&Japio
Patent JP-H05269363-A (JP)
Title: Cooler of autoclave
IPC: B01J3/00
Filed: 1992-03-25
Abstract: PURPOSE:To finely control temps., to change the cooling rate over a wide range and to prolong the service life of a cooler. CONSTITUTION:A heater 3 and a cooler 2 set in a pressure vessel 1 are controlled to form a material to be treated in an autoclave. A cooling water source 11 for supplying cooling water to the cooler 2, a gas source 21 for supplying gas to the cooler 2 and the feed water pipeline 12 and gas pipeline 22 for supplying cooling water and gas to the cooler 2 respectively interposed between with stop valves 13 and 23 are provided. Further, a mist generator 31 connected to the pipelines 32 and 34 branched respectively from the pipelines 12 and 22, a stop valve 33 connected to the pipeline 32 and a pipeline 47 for connecting the mist generator 31 and the cooler 2 are furnished.
Patent JP-H10294985-A (JP)
Title: Speaker
Inventor: FUJIHIRA MASAO
IPC: H04R9/02
Filed: 1997-04-17
Abstract: PROBLEM TO BE SOLVED: To provide a small-sized speaker advantageous for low frequency sound radiation capable of damping Q at the time of resonance at a low band resonance frequency and sensitivity by providing a second ring-like magnet between a firs ring-like magnet and a center pole, disposing firs and second plates on the first and second ring-like magnets and respectively providing first and second coils for driving in magnetic gap parts. SOLUTION: Between the first ring-like magnet 3 for forming a first magnetic circuit and the center pole 4a erected on a yoke 4, the second ring-like magnet 35 thinner than the thickness of the first ring-like magnet is disposed on the yoke 4. Also, the first and second plates 1 and 37 are disposed on the first and second ring-like magnets 3 and 35 and first and second magnetic gap parts 17 and 38 are formed between the first and second plates 1 and 37 and the outer diameter of the center pole 4a. The respective first and second coils 8 and 36 for driving are disposed to the magnetic gap parts 17 and 38 and driving force is added.