baber/WOPTO huggingface dataset:
Patent EP-4173187-A1 (EP)
Title: Slot aggregation in single frequency network
Inventor: BAI TIANYANG
IPC: H04L1/08
Filed: 2021-05-14
Abstract: A user equipment (UE) receives a configuration from a base station for receiving multiple repetitions of a transmission in a slot aggregation. The UE receives an indication indicating one or more beams used for the multiple repetitions of the transmission. The UE receives a first repetition of the transmission in a first slot based on single frequency network (SFN) operation using at least one configuration that is different from a configuration used for receiving a second repetition in a second slot based on non-SFN operation. The UE optionally determines, based on the indication, whether repetitions within the multiple repetitions of the transmission are transmitted by the base station based on the SFN operation or the non-SFN operation.
Patent EP-4153963-A1 (EP)
Inventor: WAGNER NORMAN J
IPC: G01N11/00
Filed: 2021-05-17
Abstract: La présente invention concerne des dispositifs de cellule d'échantillon et des ensembles supports. La cellule d'échantillon comprend un nouveau cylindre concentrique et une conception de revêtement avec un entraînement par engrenage à angle droit qui permet des mesures rhéologiques améliorées dans le plan de cisaillement de 1-2. La cellule d'échantillon peut être utilisée avec un ensemble support qui permet une commutation efficace entre le plan de cisaillement 2-3, le plan de cisaillement 1-3 et le plan de cisaillement 1-2 sans avoir à retirer l'échantillon et permettre une imagerie simultanée, par exemple, avec SANS ou SAXS. La présente invention porte également sur des procédés permettant d'utiliser la cellule d'échantillon et des ensembles supports dans un environnement d'échantillon 4D-SANS ou 4D-SAXS.
Patent EP-4168112-A1 (EP)
Title: Defining dose rate for pencil beam scanning
Inventor: FOLKERTS MICHAEL
IPC: A61N5/10
Filed: 2021-06-08
Abstract: The dose rate of voxels within a particle beam (e.g., proton beam) treatment field delivered using pencil beam scanning (PBS) is calculated, and a representative dose rate for the PBS treatment field is reported. The calculations account for dose accumulation in a local region or sub-volume (e.g., a voxel) as a function of time.
Patent EP-4116436-A1 (EP)
Inventor: CHOI JUNG KYOON
IPC: C12Q1/6886
Filed: 2021-01-06
Abstract: Provided are a method and system for screening neoantigen and uses of neoantigens. Specifically, provided are a method and system for screening neoantigens derived from a gene of which expression is essential for survival of a cancer cell and/or a is homogeneously expressed in all cells in cancer tissue as a diagnostic and/or therapeutic target, and uses of neoantigens.
Patent EP-4171656-A1 (EP)
Title: Bisphosphonate-modified liposomes containing nanoparticles
Inventor: GREB WOLFGANG
IPC: A61K47/69
Filed: 2021-06-25
Abstract: The invention relates to liposomes containing nanoparticles, wherein the nanoparticles are selected from magnetic, paramagnetic, superparamagnetic and/or fluorescent and/or functionalized nanoparticles, and the liposomal sleeve contains lipid-derivatized bisphosphonic acid. The liposomes are suitable for preparing a solution for the diagnosis of pathological tissue degeneration or conversion processes on the bone and in the bone marrow, in particular for the treatment and diagnosis of bone tumors and bone metastases and disorders in the bone marrow (proliferative diseases of the blood-producing and lymphoreticular system).
Patent EP-4095157-A1 (EP)
Inventor: FU YAYUAN
IPC: C07K16/22
Filed: 2021-01-22
Abstract: The present invention relates to an anti-ANGPTL3 antibody and a use thereof. In particular, the present invention relates to the anti-ANGPTL3 antibody and an antigen-binding fragment thereof, or a pharmaceutically acceptable salt or solvent thereof, and a use thereof as a medicine, in particular a use in the preparation of a medicine for treating hyperlipidemia.
Patent EP-4139942-A1 (EP)
Inventor: BENACQUISTA ERIC M
IPC: G21C17/017
Filed: 2021-05-24
Abstract: Arrangements and devices for reducing and/or preventing wear of a thermal sleeve in a nuclear reactor are disclosed. Arrangements include a first structure provided on or in one the thermal sleeve and a second structure provided on or in the head penetration adapter. At !east a portion of the first structure and at least another portion of the second structure interact to resist, reduce, and/or prevent rotation of the thermal sleeve about its central axis relative to the head penetration adapter. Devices include a base for coupling to a guide tube of the reactor and a plurality of protruding members extending upward from the base. Each member having a portion for engaging a corresponding portion of a guide funnel of the thermal sleeve.
Patent EP-4181884-A1 (EP)
Title: Formulations of 19-nor c3,3- disubstituted c21-n-pyrazolyl steroid and methods of use thereof
Inventor: WATSON PAUL STEVEN
IPC: A61P25/00
Filed: 2021-07-20
Abstract: This invention relates to a 19-nor C3,3-disubstituted C21-pyrazolyl steroid of formula (I) and pharmaceutical compositions thereof. Also disclosed herein are methods of making the pharmaceutical compositions of the 19-nor C3,3-disubstituted C21-pyrazolyl steroid of formula (I) and methods of using the 19-nor C3,3-disubstituted C21-pyrazolyl steroid of formula (I) or crystalline solid forms, pharmaceutically acceptable salts, and pharmaceutically acceptable compositions thereof.
Patent EP-4192979-A1 (EP)
Inventor: PERRY MALCOLM
IPC: C12Q1/6869
Filed: 2021-08-05
Abstract: Described herein is a method for detecting cancer DNA in a test sample of DNA from a patient. In some embodiments, the method may comprise: (a) sequencing multiple aliquots of the test sample to produce, for each aliquot, sequence reads corresponding to two or more target regions that each have a sequence variation present within the patient's cancer; (b) for each aliquot, for each target region: i. determining the number of sequence reads that have the sequence variation; ii. determining the total number of sequence reads; and iii. comparing i. and ii. to one or more error probability distribution models for the sequence variation, wherein the one or more models are obtained from DNA that does not contain the sequence variation; and (c) integrating the collective results of step (b) to determine if there is cancer DNA in the test sample.
Patent EP-4189687-A1 (EP)
Title: Apprentissage profond pour la maturation (modification) de novo de l'affinité envers les anticorps et l'amélioration des propriétés
Inventor: COSTELLO ZACHARY KOHL
IPC: G16B30/00
Filed: 2021-07-28
Abstract: Le contrôle de l'affinité et de l'expression des anticorps est essentiel pour les applications cliniques. Les anticorps à haute affinité correspondent à une spécificité supérieure et peuvent être utilisés à des doses plus faibles. Actuellement, la maturation d'anticorps est abordée avec des méthodes d'évolution dirigée. Dans ce cas, une bibliothèque initiale de liants mutés est introduite dans un processus et l'affinité est améliorée par l'intermédiaire de multiples cycles de mutation et de sélection. Cependant, la présente invention utilise une approche d'apprentissage machine pour effectuer la maturation par calcul de séquences d'anticorps en utilisant un processus ayant des parallèles avec l'évolution dirigée. Ces séquences d'anticorps peuvent être fabriquées en anticorps physiques après leur calcul et leur vérification. En outre, le procédé de la présente invention a le potentiel de surpasser l'évolution dirigée lors du ciblage d'une affinité spécifique, et est applicable aux interactions protéine-protéine générales.
Patent EP-4094856-A1 (EP)
Inventor: SASAKI SHUNSUKE
IPC: B21B19/02
Filed: 2021-01-18
Abstract: To provide a seamless pipe having excellent pressure resistance performance and a method for manufacturing the same .The seamless pipe in which a thin-walled portion in a pipe circumferential direction is formed in a pipe axial direction, in which a line segment formed by connecting one end and the other end of the thin-walled portion along a pipe surface with a shortest distance in a formation direction of the thin-walled portion is inclined at an angle α of 5.0° or more with respect to the pipe axial direction.It is preferable that one end and the other end of the thin-walled portion are set from a region in a pipe selected with a shorter length between a length of 1.0 m in the pipe axial direction and 90% of a length in the pipe axial direction where the thin-walled portion turns once in the pipe circumferential direction.
Patent EP-4199733-A1 (EP)
Title: Procédés de production de compositions de caséine non-animale, compositions de caséine et utilisation de celles-ci
Inventor: WOLFF AVIV
IPC: A23J1/20
Filed: 2021-08-17
Abstract: La présente divulgation fournit un procédé de production artificielle de micelles de caséine dans des conditions non-naturelles. La présente divulgation fournit également des micelles de caséine et des compositions de caséine comprenant les micelles de caséine. Des utilisations des micelles de caséine et/ou des compositions sont également divulguées.
Patent EP-4196342-A1 (EP)
Inventor: DE COL CHRISTIAN
IPC: B29D30/26
Filed: 2021-08-11
Abstract: A forming drum (14) is arranged, comprising radially movable, circumferentially consecutive sectors (16), each comprising a central body (18) and a pair of interchangeable inserts (23), each engaged with an axial end edge (19) of the central body (18). The forming drum (14) is brought to an expanded condition in which the sectors (16) are radially moved away from said geometric axis (X-X) in order to define a radially outer deposition surface (S) on which components of a first tyre (2) being processed are applied. During the expansion of the forming drum (14), the inserts (23) of each sector (16) are moved with respect to the respective central bodies (18) up to an operative position in which said inserts (23) extend, each on the continuation of the inserts (23) belonging to the circumferentially adjacent sectors (16), in order to form essentially continuous annular elements (31) extending along the axially opposite edges (20) of the forming drum (14).
Patent EP-4238154-A1 (EP)
Inventor: BLÁZQUEZ MARTIN JOSE ALBERTO
IPC: H01M4/32
Filed: 2021-09-15
Abstract: It is provided a secondary zinc-air electrochemical cell comprising an air cathode that is a bifunctional air electrode (BAE); a zinc-containing anode; a free electrolyte contained in a reservoir; and a first and a second separators; wherein the zinc-containing anode is disposed between the BAE and the free electrolyte, and is separated from the BAE by the first separator and separated from the free electrolyte by the second separator. It is also provided a process for the preparation of the secondary zinc-air cell, and a battery comprising at least one cell, and wherein no free electrolyte contained in a reservoir is disposed between the BAE and the zinc-containing anode.
Patent EP-4125478-A1 (EP)
Inventor: RANSON ROBERT
IPC: A42B1/00
Filed: 2021-03-30
Abstract: A protective shield features a single-piece transparent dome or shell having a rear opening through which facial and cranial regions of a user's head are received, thereby providing improved coverage over conventional face shields that cover the face only. Inward protrusions at a transitional region between the facial and cranial portions of the shield rest against the forehead to offset the facial portion of the shield forwardly of the user's face to allow airflow, optionally introduced from an external fan via an airflow channel integrally formed in the cranial portion. A flexible connector clip has a J-shaped profile for engaging an out-turned flange around the boundary of the shield' s rear opening, to enable clipped connection of a bib or shroud. Support protrusions in an underside of the cranial portion maintain airspace above the head, which is further optimized by a rearwardly sloped incline of the cranial portion.
Patent EP-4141541-A1 (EP)
Inventor: MIZOKAMI Yosuke
IPC: G03B21/14
Filed: 2021-04-20
Abstract: An object of the present disclosure is to suppress an increase in temperature. A projection system (100) includes a light source unit (1), a spatial light modulation unit (3), and a projection optical system (4). The light source unit (1) includes an optical fiber (2), a first light source part (11), and a second light source part (12). The optical fiber (2) includes a light incident portion (21), a light emerging portion (22) and a wavelength-converting portion. The wavelength-converting portion is disposed between the light incident portion (21) and the light emerging portion (22). The wavelength-converting portion includes wavelength-converting elements. The wavelength-converting elements are able to be excited by excitation light (P1) to produce spontaneous emission of light having a longer wavelength than the excitation light (P1), and also excited by amplified spontaneous emission of light. The first light source part (11) makes the excitation light (P1) incident on the light incident portion (21). The second light source part (12) makes seed light (P2) incident on the light incident portion (21). The seed light (P2) causes the wavelength-converting elements excited by the excitation light (P1) or the amplified spontaneous emission of light to produce stimulated emission of light.
Patent EP-4232327-A1 (EP)
Inventor: KERBER-WUNDERLICH HENNING
IPC: B60T8/1755
Filed: 2021-10-06
Abstract: The invention relates to a method for yaw rate regulation, wherein a yaw rate regulation function (2) for stabilising a vehicle carries out wheel-specific braking interventions on the basis of a first reference yaw rate. In order to ensure a greater level of safety, a deactivation function (3, 4) is provided which activates the yaw rate regulation function (2) as soon as at least one activation prerequisite is met, wherein at least the following is checked as the activation prerequisite: - whether a longitudinal deceleration is greater, in particular by a sensor tolerance, than a longitudinal deceleration limit value; - whether a transverse acceleration is greater, in particular by a sensor tolerance, than a transverse acceleration limit value; and - whether a deviation between a second reference yaw rate and a measured yaw rate is greater, in particular by a sensor tolerance, than a yaw rate deviation limit value.
Patent EP-4143415-A1 (EP)
Inventor: POND NICHOLAS
IPC: E21B17/02
Filed: 2021-04-28
Abstract: A tool for removing of one or more outer layers of a multi-layered jacketed wire includes a base member and a top member pivotally connected to the base member. The scoring tool has a first receiver recess on a first end of the scoring tool. A first cutter extends into a first receiver recess at a distance (d 1 ) from an interior wall of the first receiver recess, and the first cutter is transversely oriented within the first receiver recess. A second cutter extends into a second receiver recess at a distance (di) from an interior wall of the second receiver recess, and the second cutter is longitudinally oriented within the second receiver recess.
Patent EP-4256639-A1 (EP)
Inventor: PLOPPA MARTIN
IPC: H01M10/0525
Filed: 2021-10-27
Abstract: Die Erfindung betrifft eine Entgasungseinheitsanordnung (500) zum Verschluss einer Gehäuseöffnung (24) eines Batteriegehäuses (20), umfassend wenigstens zwei Entgasungseinheiten (100, 200), welche aneinander anschließend angeordnet sind, wobei wenigstens zwei der Entgasungseinheiten (100) als Endstück ausgebildet sind, und wobei die Entgasungseinheiten (100, 200) jeweils wenigstens umfassen einen Träger-Körper (31), wobei der Träger-Körper (31) jeweils wenigstens einen, eine Gasdurchgangs-Öffnung (36) umlaufenden Rand (94) aufweist, welcher wenigstens einen Befestigungsdom (110, 210) und wenigstens einen in dem Rand (94) ausgebildeten Anlagebereich (114, 214) aufweist, wobei der wenigstens eine Befestigungsdom (110, 210) einer Entgasungseinheit (100, 200) im montierten Zustand wenigstens bereichsweise mit dem korrespondierenden wenigstens einen Anlagebereich (114, 214) der angrenzenden Entgasungseinheit (100, 200) in axialer Richtung (L) einen Überlappungsbereich (130, 230) ausbildet. Zudem betrifft die Erfindung eine Entgasungseinheit (100, 200) sowie die Verwendung einer Entgasungseinheit (100, 200) in einer Entgasungsanordnung (500) und ein Batteriegehäuse (20) mit einer Entgasungseinheitsanordnung (500).
Patent EP-4151206-A1 (EP)
Inventor: TAKEBE TAKANORI
IPC: A61K33/00
Filed: 2021-05-13
Abstract: [Abstract] The present invention provides a pharmaceutical composition for use in administering oxygen to a subject, the pharmaceutical composition containing a perfluorocarbon dissolving oxygen therein. The present invention also provides a pharmaceutical composition for use in decreasing the blood carbon dioxide partial pressure of a subject, the pharmaceutical composition containing a perfluorocarbon.
Patent EP-4150561-A1 (EP)
Title: System and method for digital optical aberration correction and spectral imaging
Inventor: BERLATZKY YOAV
IPC: G01J9/02
Filed: 2021-05-12
Abstract: There are provided systems and methods for digital optical aberration correction and spectral imaging. An optical system may comprise an optical imaging unit, to form an optical image near an image plane of the optical system; a wavefront imaging sensor unit located near the image plane, to provide raw digital data on an optical field and image output near the image plane; and a control unit for processing the raw digital data and the image output to provide deblurred image output, wherein the control unit comprises a storage unit that stores instructions and a processing unit to execute the instructions to receive the image input and the raw digital data of the optical field impinging on the wavefront imaging sensor and generate a deblurred image based on an analysis of the optical mutual coherence function at the imaging plane.
Patent EP-4241369-A1 (EP)
Inventor: CESA TIAGO
IPC: H02K1/276
Filed: 2021-11-03
Abstract: La présente divulgation porte sur un rotor (6) pour une machine électrique (1). Le rotor (6) comporte une pluralité de pôles (9-n) de rotor possédant chacun au moins une ouverture (11). Ladite ouverture (11) comprend une chambre (12) destinée à recevoir un aimant (10) ; et au moins une barrière de flux (13) destinée à réguler le trajet à travers lequel le flux magnétique circule dans le rotor (6). Les pôles (9-n) de rotor comportent chacun au moins un guide de flux (15) destiné à guider le flux magnétique à travers ladite barrière de flux (13) pendant un événement de démagnétisation. Le ou les guides de flux (15) forment un étranglement (CN1) entre la chambre (12) de réception d'aimant (10) et la barrière de flux (13). La présente divulgation porte également sur une machine électrique (1) comprenant un rotor (6) ; et un véhicule (V) comprenant une machine électrique (1).
Patent EP-4153849-A1 (EP)
Title: Cooling system and vehicle comprising such a cooling system
Inventor: MOHLIN MARTIN
IPC: B60K11/02
Filed: 2021-05-06
Abstract: A cooling system comprising a cooling circuit (10) with a deaeration device (40) arranged in the cooling circuit for separation of air bubbles from coolant circulating therein. The deaeration device comprises a deaeration chamber (41) having a coolant inlet (43) connected to a feed pipe (15) of the cooling circuit, a first coolant outlet (44) connected to a coolant pump (12) of the cooling circuit, and a second coolant outlet (45) connected to an expansion tank (30) via a static line (5). The deaeration chamber has a larger cross-sectional dimension than said feed pipe. The second coolant outlet (45) is located in such a position in relation to the coolant inlet (43) and the first coolant outlet (44) that the coolant flow in the deaeration chamber between the coolant inlet and the first coolant outlet will move migrating air bubbles in the longitudinal direction of the deaeration chamber towards the second coolant outlet (45).
Patent EP-4158670-A1 (EP)
Inventor: ANDREE WYATT
IPC: H01G11/24
Filed: 2021-06-02
Abstract: Disclosed herein is an energy storage apparatus suitable for mounting on a printed circuit board using a solder reflow process, the apparatus comprising a sealed housing body comprising a positive internal contact and a negative internal contact each disposed within the body and each respectively in electrical communication with a positive external contact and a negative external contact, each of the external contacts providing electrical communication to the exterior of the body; an electric double layer capacitor (EDLC) energy storage cell disposed within a cavity in the body comprising a stack of alternating electrode layers and electrically insulating separator layers; an electrolyte disposed within the cavity and wetting the electrode layers; a positive lead electrically connecting a first group of one or more of the electrode layers to the positive internal contact.
Patent EP-4252179-A1 (EP)
Title: Quality maps for optical coherence tomography angiography
Inventor: DE SISTERNES LUIS
IPC: G06T7/00
Filed: 2021-11-29
Abstract: A system, method, and/or device for determinizing a quality measure of OCT structural data and/or OCTA functional data uses a machine learning model trained to provide a single overall quality measure, or a quality map distribution for the OCT/OCTA data based on the generation of multiple features maps extracted from one or more slab views of the OCT/OCTA data. The extracted feature maps may be different texture-type maps, and the machine model is trained to determine the quality measure based on the texture maps.
Patent EP-4256183-A1 (EP)
Title: Exhaust pipe
Inventor: HOGAN KEITH D
IPC: F01N13/18
Filed: 2021-11-09
Abstract: An exhaust pipe includes a first end, a second end, and a wall connecting the first end to the second end. The first end has a first opening, and the second end has a second opening that fluidly communicates with the first opening to define a bore. The wall includes an inner curved second and an outer curved section that includes an indentation. The indentation includes a first inwardly extending part and a second inwardly extending part. The second inwardly extending part includes a through hole having an inner opening and an outer opening. The inner opening is located between the outer opening and the second opening. A diameter of the outer opening is less than a diameter of the inner opening. A thickness of the second inwardly extending part is less than the diameter of the outer opening.
Patent EP-4251725-A1 (EP)
Title: Modular fixed-bed bioreactor systems and methods of using the same
Inventor: SEETO PAUL KEVIN
IPC: C12M1/12
Filed: 2021-11-17
Abstract: A fixed-bed bioreactor system for culturing cells is provided. The system includes a plurality of cell culture subunits, each cell culture subunit including a distribution plate with a major surface to support a cell culture substrate, an inlet, and a plurality of outlets disposed on the major surface and in fluid communication with the inlet. The subunit also includes a cell culture substrate disposed on the major surface of the distribution plate. The system further includes a plurality of input lines for supplying at least one of cells, cell culture media, nutrients, and reagents to the plurality of cell culture subunits, each input line of the plurality of input lines being fluidly connected to the inlet. The plurality of outlets is configured to distribute at least one of cells, cell culture media, nutrients, and reagents from the plurality of input lines substantially uniformly across the cell culture substrate.