baber/WOPTO huggingface dataset:
Patent CA-2105618-C (CA)
Inventor: NAKAMURA KAZUYASU
IPC: C12N15/85
Filed: 1993-09-07
Granted: 2009-11-03
Abstract: Chimeric human antibody expression vectors are constructed by inserting the antibody heavy chain variable region-encoding cDNA and antibody light chain variable region-encoding cDNA isolated from hybridomas producing a mouse or rat monoclonal antibody reacting with the ganglioside GM2 respectively into an expression vector for use in animal cells which contains the human antibody heavy chain constant region- or human antibody light chain constant region-encoding cDNA. The expression vectors are introduced into animal cells and the transformant thus obtained is cultured for the production of a chimeric human antibody reacting with the ganglioside GM2. In contrast to mouse monoclonal antibodies, the chimeric human antibodies of the invention will not cause anti-mouse immunoglobulin antibody production in the patient's body but shows a prolonged blood half-life, with a reduced frequency of adverse effects, so that it can be expected to be superior to mouse monoclonal antibodies in the efficacy in the treatment of human cancer, for instance.
Patent CA-2107028-C (CA)
Inventor: MCKNIGHT DARWIN T
IPC: A47L9/00
Filed: 1993-09-27
Granted: 1998-11-24
Abstract: A rear mounted hose and tool rack is provided for an upright vacuum cleaner.  The hose and tool rack receives and maintains various tools and attachments within a confined envelope maintained rearwardly of the lower handle assembly of the vacuum cleaner.  The rack is formed of a flexible plastic material to accommodate ease of attachment thereto.  A central opening in the rack may be passed over the upper handle assembly such that a pocket at the top of the opening may engage an upper surface of the lower handle assembly while spaced apart tabs extending into the opening engage opposite surfaces of the lower handle assembly to complete the secured engagement.  Attachment of the rack to the upright cleaner is further facilitated by the flexible and deflectable nature of the rack itself which allows the tabs to be deflected while being positioned for ultimate secured engagement.  The central opening of the rack is substantially congruent with the lower handle assembly configuration to provide further strength and rigidity to the final structure.
Patent CA-2108021-C (CA)
Inventor: MILLIMAN GEORGE E
IPC: C07C11/04
Filed: 1992-03-24
Granted: 1997-11-25
Abstract: Méthode pour éliminer les impuretés dans des circuits d'hydrocarbures, de préférence dans les fractions légères de queue, comme le propylène et l'éthylène, et dans la phase liquide, qui consiste à mettre en contact le flux d'hydrocarbures renfermant une quantité initiale d'une certaine impureté avec un adsorbant chimique, constitué d'alumine modifiée possédant une aire surfacique d'environ 10 m2/g à environ 300 m2/g et un volume poral d'environ 0,1 mL/g à environ 1 mL/g, dans des conditions permettant d'obtenir un flux purifié d'hydrocarbures, renfermant un montant réduit d'impuretés, soit moins de 0,5 % par rapport à la quantité initiale d'impuretés acides présentes dans le circuit d'hydrocarbures, et de préférence moins de 10 p.p.milliard. La présente invention porte également sur des circuits d'hydrocarbures, par exemple de propylène et d'éthylène, renfermant une quantité réduite d'impuretés, soit moins de 0,5 % environ du montant initial d'impuretés présentes dans les fractions légères de queue, et de préférence moins de 10 p.p.milliard environ. Les impuretés comme CO2, COS, H2S ainsi que H2O, AsH3 et PH3 peuvent être éliminées dans les fractions légères de queue en mettant en contact le circuit d'hydrocarbures avec un adsorbant chimique constitué d'une alumine modifiée, possédant une aire surfacique d'environ 10 m2/g à environ 300 m2/g et un volume poral d'environ 0,1 mL/g à environ 1 mL/g avec, de préférence, une masse volumique apparente d'environ 40 lb/pi3 à environ 60 lb/pi3, et une forme sphérique d'environ 1/16" à environ 3/8" de diamètre.
Patent CA-2109613-C (CA)
Title: Fluoroalkoxybenzylamino derivatives of nitrogen containing heterocycles
Inventor: LOWE JOHN ADAMS III
IPC: C07C47/55
Filed: 1992-05-05
Granted: 1996-11-19
Abstract: The present invention relates to novel fluoroalkoxybenzylamino derivatives of nitrogen containing heterocyclic com-pounds, and specifically, to compounds of formula (I) wherein Q, X1, X2 and X3 are as defined below. These novel compounds are useful in the treatment of inflammatory and central nervous system disorders, as well as other disorders.
Patent CA-2116543-C (CA)
Inventor: GREISEN KAY S
IPC: C12P19/34
Filed: 1992-07-31
Granted: 2007-10-02
Abstract: Methods and reagents are provided for detecting bacterial nucleic acids in cerebrospinal fluid. In a preferred embodiment, a panel of probes is provided for detecting and identifying causal agents of meningitis.
Patent CA-2119917-C (CA)
Title: Gas emission spectrometer and method
Inventor: MALCZEWSKI MARK LEONARD
IPC: G01N21/69
Filed: 1994-03-23
Granted: 1999-06-01
Abstract: A gas emission spectrometer and method for analyzing a continuously flowing gas stream using gas emission spectroscopy to measure low concentration levels of one or more gas/vapor impurities in the gas stream.  Alternating power is applied to an electric discharge source to generate emissive radiation which is filtered into an optical signal at the emission wavelength of a preselected impurity gas.  The optical signal is converted into an electrical signal which is selectively amplified within a narrow frequency range centered at substantially twice the excitation frequency of the alternating power source.  The impurity concentration is measured from the amplified signal upon rectification.
Patent CA-2123533-C (CA)
Title: Electrical connection
Inventor: HOPPER HANS PAUL
IPC: H01R13/523
Filed: 1994-05-13
Granted: 2004-09-28
Abstract: An electrical connection across a peripheral surface through a sealed enclosure (34A) in a radial plane between a tubing hanger (5) and a surrounding support member (3).      The connection involves a coupling element (17) in the tubing hanger and a shuttle which can reciprocate from a position wholly within the support member, across the interface and into electrical connection with the coupling element, without producing any movement of a cable (9,10,11,15) leading into a sealed enclosure within the support.
Patent CA-2127723-C (CA)
Title: Gripping device for timber
Inventor: NICKEL DONALD C
IPC: E06C1/38
Filed: 1994-07-05
Granted: 2003-12-16
Abstract: A gripping device is provided for use with vertical or near vertical timbers on building sites, especially with 2" x 4", 2" x 6", or 2" x 8"  planks, and which allows such timbers to be used with a series of the devices forming steps of a temporary ladder. The timber may be leaning against a surface, or may be part of a scaffold or studs of a house. The device may be formed of a single piece of rod, or as a casting. 1t has a closed loop part suitable for use as a step, and also has a retaining part, the retaining part and loop having parallel portions defining an open sided recess for receiving the timber. At least one of the parallel portions has a set of teeth facing the other parallel portion, such that the device can be slid sideways on to a timber and can be pivoted down to cause the teeth to engage the timber and prevent further movement of the device.
Patent CA-2133796-C (CA)
Title: Fuel compositions and additives therefor
Inventor: MALFER DENNIS J
IPC: C10L10/00
Filed: 1994-10-06
Granted: 2005-08-23
Abstract: A highly effective fuel additive composition for control of intake valve deposits is described. It comprises (a) a gasoline-soluble Mannich reaction product of (i) a high molecular weight alkyl-substituted phenol wherein the alkyl group has a number average molecular weight of from about 600 to about 3000, (ii) amine, and (iii) aldehyde; and (b) a gasoline-soluble poly(oxyalkylene) compound having a viscosity in its undiluted state of at least about 70 cSt at 40°C and at least about 13 cSt at 100°C. These components are proportioned such that there are from about 0.2 to about parts by weight of active Mannich base in (a) per part by weight of (b).
Patent CA-2133971-C (CA)
Title: A process of preparing hexafluorobutane
Inventor: BIELEFELDT DIETMAR
IPC: B01J23/755
Filed: 1993-05-03
Granted: 2003-12-16
Abstract: 1,1,1,4,4,4-hexafluorobutane is obtained from a trifluoroethane compound, by reacting this with hydrogen in the gas phase and without a diluent on a palladium- and/or nickel-containing supported catalyst and subsequently hydrogenating the reaction product.
Patent CA-2135278-C (CA)
Title: Peptide for stimulation of cytotoxic t lymphocytes specific for hepatitis c virus
Inventor: BERZOFSKY JAY A
IPC: A61K39/00
Filed: 1993-06-10
Granted: 2005-08-09
Abstract: The cytotoxic T cell response to the protein encoded by the NS5 region of hepatitis C virus was determined using 28 peptides from NS5 which were selected by an amphipathicity algorithm as candidates for T cell epitopes. In BALB/c mice, a single relatively conserved epitope represented by a 16-residue synthetic peptide was presented by D d class I major histocompatibility complex (MHC) molecules to conventional CD4-CD8 + CTL. An exemplary peptide, which represents amino acid residues 2422-2437 of the polyprotein of the Chiron HCVI isolate, had the amino acid sequence MSYSWTGALVTPCAAE {SEQ ID NO: 1}. A CTL line specific for this peptide recognized the two known natural variants of this NS5 sequence, each with conservative substitutions. Thus, CTL can recognize the product of the HCV NS5 gene, the probable RNA polymerase, in association with class I MHC molecules on model target cells and may recognize the same epitope on hepatocytes or any other cells infected with the virus.
Patent CA-2143818-C (CA)
Inventor: ESCHBACH STEPHEN L
IPC: G01F23/24
Filed: 1995-03-02
Granted: 1998-06-16
Abstract: A system for monitoring the water level of a pressure drum  having  a  pressure  column  comprises  a  plurality of electrodes communicating with the column for contacting water and steam within the column.   Each electrode has its own location and produces a first output which corresponds to the presence of water or a second output which corresponds to the presence of steam.  A discriminator is operatively connected to the electrodes; and the discriminator has an analog-to-digital converter for receiving the output of each electrode and converting the output to a digital signal which represents the  water  conductivity  for  each  electrode.    A  central processor is operatively connected to the discriminator for powering the discriminator as well  as  for receiving the digital signals in order to determine a slope degradation between the conductivity and the location of each electrode in the  column.    The  central  processor also  determines  an inflection point between the water and the  steam in the column.   An LED display is used to indicate which of the electrodes are located in water and which of the electrodes are located in steam.
Patent CA-2145527-C (CA)
Title: Tissue protective and regenerative compositions
Inventor: PICKART LOREN R
IPC: A61P17/00
Filed: 1993-09-28
Granted: 2008-01-15
Abstract: Methods are provided for preparing compositions suitable for protecting irritated or damaged skin from further oxidative and biochemical damage and thus permitting natural healing processes to progress, for accelerating the rate of healing of burns and surgical wounds, and for increasing the size of hair follicles and the rate of hair growth. The compositions generally comprise precipitates formed by the complexation of peptone digests of various proteins with copper(II) salts, indium(III) salts, tin(II) salts and tin(IV) salts.
Patent CA-2152459-C (CA)
Title: Adaptor for connecting tubes to an animal
Inventor: HIRUTA MASAHIRO
IPC: F16L39/06
Filed: 1995-06-22
Granted: 2005-04-12
Abstract: Coaxial infusion pipes are disposed in a fixed shaft body and the ends of the pipes pass into a rotary shaft body.      The fixed shaft body and the rotary shaft body are rotatably joined by bearings. Packings are provided inside the rotary shaft body in correspondence with the pipes. Only lip portions of the packings are in sliding contact with the pipes. The sliding resistance between the infusion pipes and the packings as seal members is low, and the rotary shaft body can rotate extremely lightly and with high precision.
Patent CA-2153589-C (CA)
Title: A ball-point pen
Inventor: KOBAYASHI SEIICHI
IPC: B43K1/08
Filed: 1994-12-05
Granted: 1999-05-11
Abstract: A ball-point pen capable of preventing backflow which is liable to occur during writing with the ball-point upward. The ball-point pen (1) comprises a tip (15), of which an end protrudes from a cap (7) with a ball-point pen refill (3) rotatably holding at the front end thereof a small ball (13) for writing by caulking, an ink storage tube (17), in which ink is filled for supplying of ink to the tip, and a joint (19) which connects the ink storage tube to the tip to permit ink to be fed from the ink storage tube to the tip. Formed on the joint are a tip side hole (37a) and an ink storage tube side hole (33a) which permit ink to pass therethrough when the joint is fitted into the tip and the ink storage tube, respectively. The tip side hole and the ink storage tube side hole communicate to each other through a connection hole (45) which comprises a large diameter portion (45b) and a small diameter portion (45s) adapted to connect to the tip side hole and the ink storage tube side hole, respectively, and is eccentric with respect to the both holes. A large ball (49) having a larger diameter (1s) of the small diameter portion is movably disposed in at least a portion (47) of a space which is formed between a rear end of the tip and the large diameter portion when the tip is fitted in the tip side hole.
Patent CA-2153995-C (CA)
Inventor: BEITELMAN LEONID
IPC: B22D11/115
Filed: 1994-01-14
Granted: 2000-11-07
Abstract: An induction stirring method wherein molten metal is elec-tromagnetically stirred during continuous casting in a mold includes control of meniscus depression, either to decrease or enhance the stirring of the molten metal produced by the main electromagnetic stirrer.  An A.C. magnetic stirring modifier is positioned adjacent the region of meniscus to produce electromagnetic stirring of the molten metal at the meniscus, either to oppose the rotary motion of the main electromagnetic stirrer and provide a surface free from turbulence or to enhance the rotary motion of the main magnetic stirrer. These two alternative modes of operation permit a casting machine to be used for casting molten metals requiring widely varying operating condi-tions.
Patent CA-2156207-C (CA)
Inventor: FUJII ISAO
IPC: F16H63/20
Filed: 1995-08-16
Granted: 1999-05-04
Abstract: An object of the present invention is to provide a reverse gear squeal-preventing device capable of preventing a reverse gear squeal without increasing an operating force, which device can be realized with fewer components and at lower cost, and further which can be adapted for use in differently structured transmissions. In addition, the device ensures that a forward stage-shifting yoke, which has slightly been moved during reverse gear squeal-preventing operation, can be returned to a neutral position.  Further, the device can reduce an impinging noise of a plate-holding bolt at the selecting time, and provides downsizing of the interlocking plate. To this end, the device according to the present invention comprises:  a cam member attached to a shifting and selecting shaft so as to be axially movable and circumferential immovable for driving the forward stage-shifting yoke into slight movement in a forward stage-shifting direction at the beginning of the reverse-shifting time; a guide member attached to the cam member so as to be axially movable; a cam spring biased against both of the cam member and a support, the support being fixedly mounted on the shaft; a forward stage-selecting spring biased against both of the cam member and the support via the guide member; and, a restriction portion for limiting movement of the guide member in a forward stage-selecting direction at the time of forward stage selecting.
Patent CA-2156617-C (CA)
Title: A method of separating sulphur compounds
Inventor: STIGSSON LARS
IPC: D21C11/06
Filed: 1994-03-04
Granted: 2001-08-14
Abstract: A method of separating sulphur compounds out of a gas containing carbon dioxide and hydrogen sulphide, in a gas washing system, said gas being obtained by gasification of spent cellulose liquor. According to the invention the gas washing system has a gas-liquid contact zone (5) operating at a pressure exceeding atmospheric pressure as well as a regeneration zone (8) operating at a pressure substantially  less than the pressure in the gas-liquid contact zone (5). The carbon dioxide partial pressure in the gas prior to entering the gas-liquid contact zone exceeds 0.2 atm.  Furthermore the gas comes into contact with an alkaline absorption liquid in the gas-liquid contact zone, and alkaline liquid containing alkali hydrogen sulphide is withdrawn from the gas-liquid contact zone and transferred to the regeneration zone, in which zone hydrogen sulphide is expelled from said liquid containing alkali hydrogen sulphide and withdrawn in the form of a gas.
Patent CA-2158163-C (CA)
Inventor: JARUZEL KURT
IPC: E04G17/14
Filed: 1994-06-29
Granted: 2005-06-28
Abstract: Un panneau de coffrage (1) comporte une chemise de coffrage (2) et des supports (4) qui soutiennent la chemise de coffrage du côté opposé au béton, ainsi qu'éventuellement des entretoises marginales (3) approximativement parallèles aux supports (4). Des panneaux de coffrage (1) adjacents peuvent être accouplés et assemblés les uns aux autres. Les supports (4) ont une section transversale approximativement en U. Les branches (5) du U s'écartent en biais l'une de l'autre, depuis une entretoise transversale. A leurs extrémités libres où leur écart mutuel est le plus important, les branches du U comportent des brides de fixation (7) permettant de les relier à la chemise de coffrage (2). Afin de prolonger au moins d'un côté le panneau se trouvant dans le prolongement du sens d'extension longitudinale des supports (4), chaque support (4) se compose de deux parties ou de deux sections (4a et 4b), déplaçables l'une par rapport à l'autre et qui se chevauchent du moins dans une zone de recouvrement. A l'intérieur de sa section transversale, l'angle d'inclinaison formé par les branches en U de la section (4b) située à l'intérieur et par la chemise de coffrage (2) est plus obtus ou plus grand que l'angle correspondant de la section (4a) de recouvrement, ou bien l'angle situé entres les deux branches du U de la section (4b) intérieure est plus aigu que l'angle correspondant situé entre les branches du U (5) de la section (4a) située à l'extérieur. Les angles sont choisis de manière à ce que lorsque les entretoises transversales en U (6) sont adjacentes, la largeur intérieure entre les branches du U (5) de la section (4b) intérieure, sur la chemise de coffrage (2), soit inférieure de la largeur totale des brides de fixation (7) écartées l'une de l'autre, à la largeur intérieure de la section (4a) extérieure au même endroit, de manière à ce que les brides de fixation (7) des deux sections se trouvent à côté l'une de l'autre dans le même plan, lorsque la chemise de coffrage (2) est plane.
Patent CA-2162910-C (CA)
Title: Improvements in pharmaceutical containers
Inventor: REYNOLDS DAVID L
IPC: A61M5/28
Filed: 1994-05-16
Granted: 1999-09-21
Abstract: A bottomless pharmaceutical vial for filling, capping, and subsequent conversion into a syringe includes a shoulder (14) within its open bottom end (8) beneath a piston (10), and a retainer ring (20) snapped into engagement with the shoulder to retain the piston. The retainer ring has no part projecting beyond the external diameter of the vial, so that it may be installed prior to filling of the vial. A separate finger flange (32) may subsequently be snapped into place if required.
Patent CA-2164679-C (CA)
Inventor: STANDKE BURKHARD
IPC: C09K23/54
Filed: 1995-12-07
Granted: 2006-05-23
Abstract: Disclosed are water-based organopolysiloxane-containing compositions which are essentially free from organic solvents, have a flashpoint above 80°C and essentially liberate no alcohols by hydrolysis on dilution with water. The organopolysiloxane-containing compositions are obtainable by mixing water-soluble aminoalkylalkoxysilanes with alkyltrialkoxy-silanes, dialkyldialkoxysilanes or mixtures thereof which are not water-soluble, adding water to the mixture, adjusting the pH of the reaction mixture to a value of between 1 and 8 and removing the alcohol already present or formed during the reaction. A process for the preparation of the organopolysiloxane-containing compositions and their use are also disclosed.
Patent CA-2165871-C (CA)
Title: Parison forming apparatus and parison forming method
Inventor: TAKASHIMA TADAYOSHI
IPC: B29C49/00
Filed: 1994-12-21
Granted: 2002-03-26
Abstract: A parison forming apparatus excellent in working efficiency and a parison forming method are provided. A moving plate which possesses core feed rows composed of multiple core receiving holders for feeding the multiple heat resistant resin cores to the mold device, and parison takeout rows composed of multiple parison receiving holders for taking out and receiving already formed multiple parisons from the mold device, being formed at a distance of a specific pitch interval from the core feed rows, and feeds the heat resistant resin cores from the core feed rows into the mold device which is empty after the parisons are taken out.
Patent CA-2168387-C (CA)
Inventor: BROWN SCOTT H
IPC: B01J23/66
Filed: 1996-01-30
Granted: 1999-07-13
Abstract: A catalyst composition comprises palladium, at least one chemically bound alkali metal (preferably potassium), chemically bound fluorine and an inorganic support material (preferably alumina), wherein the atomic ratio of fluorine to alkali metals about 1.3:1 to about 4:1. Preferably, silver is also present in the catalyst composition. The above-described catalyst is employed as a catalyst in the selective hydrogenation of C2-C10 alkynes (preferably acetylene) to the corresponding alkenes in the presence of sulfur impurities.
Patent CA-2169168-C (CA)
Title: Methode et trousses d'essai pour la detection des bacteriophages
Inventor: SANDERS MICHAEL FREDERICK
IPC: C12Q1/04
Filed: 1994-07-29
Granted: 2009-03-10
Abstract: L'invention concerne un procédé de détection, d'identification et/ou de quantification de bactériophages à spécificité d'hôte bactérien pour un genre, une espèce ou un sérotype bactérien, ledit procédé étant basé sur la libération du contenu des cellules, notamment les nucléotides comme par exemple l'adénosine triphosphate, sur la lyse des parois de cellules bactériennes lors de l'incubation avec des cellules hôtes bactériennes. Lorsque de nouvelles particules de phages sont libérées à la fin du cycle de réplication des phages, on mesure les niveaux de nucléotides et on les compare avec des témoins. Ce procédé permettant de détecter des phages spécifiques est plus rapide et plus sensible que les techniques connues; il est uniquement limité par la disponibilité des appariements bactérie hôte/phage cible.
Patent CA-2174760-C (CA)
Inventor: PYKE STEPHEN C
IPC: G01N33/00
Filed: 1994-10-27
Granted: 1999-07-13
Abstract: Un détecteur à diodes MIS (10) possédant une électrode en alliage Pd/Cu (15) est sensible aux gaz CO, H¿2?, C¿2?H¿2? et C¿2?H¿4? et peut les détecter. Un groupe (30) de détecteurs à diodes MIS (10) possédant des compositions d'électrodes variables peut indiquer une défaillance dans un transformateur électrique lors de la détection d'au moins un des gaz-clés, CO, H¿2?, C¿2?H¿2? et C¿2?H¿4?, associés à des défaillances.