Patent AU-2014271317-A1 (AU)
Title: Methods for production and uses of multipotent cell populations
Inventor: REID CHRISTOPHER B
IPC: C12N15/00
Filed: 2014-12-04
Abstract: (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) CORRECTED VERSION (19) World Intellectual Property Organization International Bureau (43) International Publication Date (10) International Publication Number 11 December 2008 (11.12.2008) W O 2008/150814 A8 (51) International Patent Classification: EG, ES, F, GB, GD GE, GIL GM, GT., HN, HR, H1U, ID, C12Q 1/68 (2006.01) A61K39/21 (2006.01) IL, IN, ISJP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, C12N 15/00 (2006.01) LK, LR, LS, IT, LU, LY, MA, MD, ME, MG, MK, MN, MW MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, (21) International Application Number: PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, PCT/US20081065007 SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (22) International Filing Date: 28 May 2008 (28.05.2008) (84) Designated States (unless otherwise indicated, for every (25) Filing Language: English kind of regional protection available): ARIPO (BW, GHl, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, (26) Publication Language: English ZW), Eurasian (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM), European (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, (30) Priority Data: FR, GB, GR, HR, HU, IE, IS, IT, IT LU, LV, MC, MT, NL, 60/932,020 29 May 2007 (29.05.2007) US NO, PL, PT, RO, SE, SI, SK, TR), OAPI (BF, BJ, CF, CG, 60/933,133 5 June 2007 (05.06.2007) US CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). 60/933,670 8 June 2007 (08.06.2007) US 61/006,449 14 January 2008 (14.01.2008) US Published: 611064,761 25 March 2008 (2503,2008) US - with international search report - with sequence listing part of description published sepa (71) Applicant and rately in electronicform and available upon request from (72) Inventor: REID, Christopher, B. [US/US]; 880 N. the International Bureau Alameda Street, Apt. 312, Los Angeles, CA 90012 (US). (88) Date of publication of the international search report: (74) Agents: FOX, James, A. et al.; Goodwin Procter LLP, 135 5 February 2009 Commonwealth Drive, Menlo Park, CA 94025 (US). (48) Date of publication of this corrected version: (81) Designated States (unless otherwise indicated, for every 30 July 2009 kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, (15) Information about Correction: CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, see Notice of 30 July 2009 (54) Title: METHODS FOR PRODUCTION AND USES OF MULTIPOTENT CELL POPULATIONS (57) Abstract: The claimed invention is directed towards the generation of pluripotent, multipotent, and/or self-renewing cells which are capable of beginning to differentiate in culture into a variety of cell types and capable of further differentiation in vivo. The claimed invention is also directed towards the generation of desirable, differentiating cell populations transplantable to patients, genetic modification of endogenous cells, and the treatment of patients suffering from diseases that may be ameliorated by these methods. This invention also provides methods for preventing, treating, or retarding disease related to immunodeficiency virus (e.g. HIV-, HIV-2, SIV, FI, etc.) infection.