baber/WOPTO huggingface dataset:
Patent UY-36076-A (UY)
Title: Compuestos útiles como inhibidores de la interacción proteínaproteína pd-1/pd-l1 y cd80/pd-l1, y composiciones farmacéuticas que los contienen.
Inventor: CHUPAK LOUIS S
IPC: C07D405/14
Filed: 2015-04-13
Abstract: La presente descripción se refiere, en general, a compuestos útiles como inmunomoduladores. En la presente se proporcionan compuestos, composiciones que comprenden estos compuestos y métodos de uso. La descripción también se refiere a composiciones farmacéuticas que comprenden al menos un compuesto de acuerdo con la descripción que son útiles para el tratamiento de diversas enfermedades, que incluyen cáncer y enfermedades infecciosas.
Patent UY-39488-A (UY)
Title: Composiciones y métodos para modular la inmunidad mediada por la cadena delta gamma
Inventor: SINGH SANJAYA
IPC: C12N15/85
Filed: 2021-10-27
Abstract: En la presente descripción, en ciertos aspectos, se proporcionan anticuerpos que se unen al receptor de células T (TCR) Vy9 (TRGV9), TCR Vd2 (TRDV2), o la región constante gamma/delta del TCR (TRGDC), así como células recombinantes que contienen los vectores y composiciones que comprenden los anticuerpos. También se proporcionan métodos para preparar y usar los anticuerpos
Patent UY-39574-A (UY)
Title: Compuesto macrocíclico útil para tratar el cáncer y composición farmacéutica que lo contiene
Inventor: CUI JINGRONG J
IPC: C07D515/14
Filed: 2021-12-17
Abstract: La presente descripción se refiere a compuestos macrocíclicos, composiciones farmacéuticas que contienen compuestos macrocíclicos y métodos para usar compuestos macrocíclicos para tratar enfermedades, tales como el cáncer.
Patent YU-34895-A (YU)
Inventor: MERINGO DE
IPC: C03C3/091
Filed: 1995-05-26
Abstract: A biologically degradable glass-fiber composition characterized by the following constituents in percent by weight:SiO<sub>2</sub>45 to 60Al<sub>2</sub>O<sub>3</sub>less than 2CaO + MgO10 to 16Na<sub>2</sub>O + K<sub>2</sub>Omore than 18 to 23B<sub>2</sub>O<sub>3</sub>10 to 18P<sub>2</sub>O<sub>5</sub>0 to 4BaO0 to 1Diverse0 to 2.
Patent YU-41396-A (YU)
Inventor: NADEZDA STOJANOVIC
Filed: 1996-07-10
Abstract: Postupak za dobijanje N-etil-N-1-naftil acilamida opšte formule (II) pri čemu R predstavlja fenil, metil, etil, propil, 1,1-dimetiletil i fenilmetil grupu, okarakterisan je prema ovom pronalasku time što reaguje, hlorid odgovarajuće kiseline sa N-etil-N-1-naftil aminom, u prisustvu 40 %-tnog vodenog rastvora natrijum-hidroksida, na temperaturi od 0-50В°C.
Patent YU-75092-A (YU)
Title: Supstituisani 1-fenil-1-benzoilamino-5-aminopentani, njihovo pravljenje i primena
Inventor: MASHKOVSKY DAVIDOVICH M
IPC: C07D295/125
Filed: 1992-07-31
Abstract: SUPSTITUISANI 1-FENIL-1-BENZOILAMINO-5-AMINOPENTANI, NJIHOVO PRAVLJENJE I PRIMENA, opisani su 1-fenil-1-benzoilamino-5-aminopentani, njihovi izomeri, njihove soli i preparati spravljeni od njih. Ova jedinjenja su pogodna za suzbijanje bolesti. gde: R1 predstavlja atom halogena, nitrogrupu, grupu C1-4-aminoacil ili grupu sulfonamido, a R2 i R3 su grupe C1-5-alkil ili zajedno obrazuju grupu C3-6-alkilen.
Patent YU-94089-A (YU)
Title: Process for preparing cyclopentan analogs of purine nucleotides
Inventor: CARUSO M
IPC: C07C225/34
Filed: 1989-05-08
Abstract: Anthracycline glycosides of formula (I) and their pharmaceutically acceptable acid addn. salts are new where R1 = H or OH; one of R2 and R3 = H, the other is H or OH. Also new are the intermediates 4-demethoxy-4-amino -7-deoxy-daunomycinone (IX) and daunomycinones (II), opt. N-protected. - (I) is pref. 4-demethoxy-4 -amino-daunorubicin; 4-demethoxy- 4-amino-4'-epi-daunorubicin or 4-demethoxy-4-amino -4'-deoxy-daunorubicin, and the corresp. doxorubicin cpds.
Patent AT-A130382-A (AT)
Inventor: WOLKENSTEIN ROBERT ING
IPC: B30B9/24
Filed: 1982-04-01
Abstract: A sieve belt press includes two endless sieve belts which pass over a number of rolls. In the area in which the two sieve belts return separately, drive rolls are provided so that each sieve belt is driven separately. In addition, at least one further drive roll is provided in an area within which the sieve belts are passed in common over such further drive roll.
Patent AT-A392001-A (AT)
Inventor: SCHNEDL KARL DIPL ING
IPC: B61L5/04
Filed: 2001-01-11
Abstract: The invention relates to a device for locking the end positions of movable switch parts and, in particular, the movable point (1) of a frog, in which two relatively axially displaceable parts are capable of being displaced into a position coupled with each other in a positive manner in at least one direction of movement, wherein the relatively displaceable parts are comprised of a tube (5) and a rod (6) guided within the tube (5) and are at least partially arranged in a stationary outer tube (4), whereby locking members (8) cooperate with the relatively axially displaceable parts (5, 6) as well as the outer tube (4) and are capable of being displaced in the radial direction into a locking position in a recess or inner annular groove (15, 16) of the outer tube (4). Said device is designed such that the outer tube (4) is comprised of two tube parts (17, 18) capable of being axially displaced within each other, and that each tube part carries at least one recess or inner annular groove (15, 16).
Patent BE-812519-A (BE)
Title: Copolymer with chelate forming gps. - thickener and gelling agents for explosives, textiles, cosmetic prods. etc.
IPC: C09D7/00
Filed: 1974-03-19
Abstract: The compn. contains a polymer which is at least partly soluble in an aqs. medium and is derived from a monomer contg. a gp. which can react with a metal ion. The monomer is e.g. methacryloylacetone and the comonomer may be acrylamide, vinylpyrrolidene, vinyl alcohol, methacrylic acid or dimethylaminoethyl methacrylate. The compn. is used as thickener or gelling agent for explosive, mine works, textiles, cosmetic, pharmaceutical or agricultural prods. and forms a stable gel.
Patent BE-897184-A (BE)
Title: Dispositif consigneur et deconsigeur pour objets utilitaires tels que des chariots a bagages,
IPC: B26B19/04
Filed: 1983-06-30
Abstract: Le dispositif comprend une serrure (3) permettant de verrouiller automatiquement chaque objet (2') à l'objet voisin (2), serrure dans laquelle on introduit une pièce de monnaie (4) pour autoriser son déverrouillage et la libération de l'objet (2') par traction, et agencée pour restituer ladite pièce lorsque l'objet est verrouillé à un objet voisin, et est caractérisé en ce que le déverrouillage est réalisé par ladite traction.
Patent BE-897599-A (BE)
Title: Dog barking sound generation appts. for intruder deterrent - includes relay responding to front door bell-push or proximity detector to actuate tape recorder playing barking sound
IPC: G08B15/00
Filed: 1983-08-25
Abstract: The barking sound reproducing apparatus includes a relay switch which is operated when the door-bell pushbutton is activated, or when a detector senses the presence or movement of a person. The detector is supplied with current from a rectifier. The relay applies a voltage to a tape recorder in order to replay a prerecorded tape of barking or other burglar or intruder deterrent noise. The tape is a continuous loop long enough to give a variety of sound, and is run for a timed interval after activation.
Patent BE-901445-A (BE)
Title: Anticancer 4':de-oxo 4':halo doxorubicin 14:ester(s) - prepd. by treating de-oxo halo:doxorubicin with bromine and an acid salt
Inventor: PENCO S
IPC: C07H15/252
Filed: 1985-01-04
Abstract: 4'-Deoxy-4'-halo doxorubicin 14-esters of formula (I) are new. R = acyl group derived from one of the following acids: mono- or di-carboxylic aliphatic, aromatic, cycloaliphatic, araliphatic, or heterocyclic, which may contain up to 20C atoms and may be substituted by any of the following: halogen, OH, alkyl, alkoxy, amino, mono or di alkylamino, nitro, alkyl or aryl carbonic acid, carbamic acid, alkyl carbamic acid, or sulphonic acid. - Prepn. has a 4'-deoxy-4'-halo daunorubicin dissolved in an anhydrous solvent and treated with bromine at ambient temp., to give the corresp. 14-bromo deriv. This is then treated with a salt ROM, where M is an alkali metal alkaline earth metal, quaternary ammonium, or quaternary alkyl ammonium, in an inert solvent.
Patent BE-901474-A (BE)
Title: Servo-mechanism for control of engine or generator - comprises electronic loop circuit setting fuel inlet according to power requirement
IPC: H02P9/04
Filed: 1985-01-10
Abstract: The system includes an electronic device which sets the gas, fuel or fluid inlet according to the working requirements of the engine. - The system comprises an electronic control circuit with a closed loop (II) which sets the operating device (III). The circuit is supplied by the driven electric generator (IV) whose operating parameters are analysed by the loop circuit (II). A surveillance system (V) cuts the supply to the circuit (II) in case of any fault. USE/ADVANTAGE - Rapid response. For land and sea vehicles.
Patent BE-902687-A (BE)
Title: Plaque refractaire et buse de coulee, et procede de montage de plaques refractaires dans une vanne coulissante.
Inventor: SHAPLAND E P
IPC: B22D41/22
Filed: 1985-06-18
Abstract: Le dispositif à plaques réfractaires formant une vanne coulissante, comprend deux plaques, l'une fixe (9) et l'autre mobile (10), formées d'une dalle réfractaire et pouvant glisser l'une contre l'autre, face à face. Ces deux plaques sont identiques et sont maintenues en place par des brides (8) qui, du fait de la conicité des bords des plaques et de leur propre conicité, appliquent à la fois des forces de bridage et des forces de compression auxdites plaques. Domaine d'application : coulée, notamment de métaux liquides tels que l'acier, etc.
Patent BE-903501-A (BE)
Title: Chateau de stockage de combustible nucleaire epuise
IPC: G21F5/10
Filed: 1985-10-22
Abstract: Ce chateau de stockage de combustible nucléaire épuisé comprend une enveloppe de confinement comportant une multiplicité d'ailettes (68) de forme allongée dont chacune comprend un élément métallique (84) comportant une paire de cotés (70,74) qui se raccordent dans une région de sommet courbée (78) et qui ont des bords de base espacés (72,76) fixés à la périphérie de ladite enveloppe. Une couche protectrice (84) est accolée à l'élément métallique dans ladite région de sommet et au moins dans une partie de chaque coté. Une matière (100) absorbant les neutrons est disposée entre les cotés de chaque ailette pour absorber les neutrons.
Patent BE-903660-A (BE)
Title: Tyre deflation indicator for trailer and caravan - uses pair of mercury switches to detect tilting of caravan and to supply current to warning device
IPC: B60C23/06
Filed: 1985-11-18
Abstract: The deflation of a tyre is detected by a pair of mercury switches mounted transversely to the direction of motion of the trailer. If the caravan leans to the left or right through an angle exceeding three degrees the switches form an electrical contact. The switches are c connected electrically in parallel and close circuit coupling the battery to a light emitting diode which serves as an indicating device in the driver's cabin. - The switches are mounted so that they are insulated from the external temperature to prevent false indications arising from thermal expansion or contraction of the mercury.
Patent BE-904577-A (BE)
Title: Passage de barres pour transformateurs electriques.
Inventor: HUERGA VICENTE LUENGO
IPC: H01F27/04
Filed: 1986-04-10
Abstract: Passage de barres pour transformateurs électriques, constitué à partir d'une pièce de base de caractère isolant électrique, de préférence en résine plastique, dont les formes et les dimension correspondent à celles de l'embouchure de la cuve et qui est surdimensionné par rapport à cette embouchure.
Patent CA-1046500-A (CA)
Title: 14,19-dioxygenated steroid compounds and their 14-dehydro analogs and processes for the preparation thereof
Inventor: KRUGER GUNTHER
IPC: C07J1/00
Filed: 1972-01-04
Granted: 1979-01-16
Abstract: ABSTRACT OF THE DISCLOSURE               There are provided new compounds having the formula          (I) wherein R is selected from the group consisting of O-acyl or O-alkyl;  OH;  O;                                             ;            :           ;         ;                               ;              ;        ;                   ;          ;             ;         ;        ;    ,   wherein alkyl is tetrahydropyranyl, lower alkyl, preferably methyl, or a substituted methyl wherein the substituent is selected form the group consisting of phenyl, halogen, prefer-ably chlorine and bromine, methoxy, CH2=CH and HC=C; wherein acyl represents a group selected from those consisting of acetate, lower trialkyl acetates wherein the lower alkyl group is preferably methyl or ethyl, monohalo acetates and trihalo acetates, preferably wherein the halogen is chlorine, fluorine and bromine; Y is selected from the group consisting of 3.alpha.-hydroxy, 3.beta.-hydroxy, O=, O-alkyl and O-acyl wherein alkyl and acyl are as defined above; the hydrogen atom in the 5-position beign 5.alpha. or 5.beta.? R' is selected from the group consisting of hydroxy, alkyloxy and acyloxy in which the alkyl and acyl groups are as defined above; the groups A and B represent ?4 or 15 carbon atoms, which are either linked by a double bond or which carry an .alpha.- or .beta.-oxido or a 14.alpha.- or 14.beta.-hydroxy group, in which case B is a methylene group, the 8-position carrying an 8.alpha.-hydrogen or 8.beta.-hydrogen atom, and wherein said compound of the formula (I) may include an optional double bond in the 4; 5;  6; 7 and/or 8(9) position. There are provided also processes for preparing such compounds.  The compounds are useful as intermediates in the preperation of further compounds.
Patent CA-1042882-A (CA)
Inventor: PAPPO RAPHAEL
IPC: C07C67/00
Filed: 1974-10-31
Granted: 1978-11-21
Abstract: ABSTRACT OF THE DISCLOSURE   3-Hydroxy-2-(4-hydroxy-1-alkynyl)-5-oxocyclopent-1-enealkanoic acids and derivatives thereof, prepared by condensation of a suitably substituted cyclopentane carboxylic acid or ester with an organometallic alkynyl derivative, are useful pharmacological agents as evidenced by their anti-ulcerogenic, anti-secretory and anti-micro-bial properties.
Patent CA-1057299-A (CA)
Inventor: TOUHEY WILLIAM J JR
IPC: C08G18/78
Filed: 1975-02-04
Granted: 1979-06-26
Abstract: Abstract of the Disclosure Biuret polyisocyanate is prepared by reacting a hin-dered polyamine and a polyisocyanate at elevated tempera-tures, in the presence of an excess of polyisocyanate.  The resulting product may be utilized to prepare an outstanding foam composition.
Patent CA-1046361-A (CA)
Inventor: RUTLEDGE WILLIAM W
IPC: C04B28/04
Filed: 1975-05-12
Granted: 1979-01-16
Abstract: ABSTRACT OF THE DISCLOSURE       A rolled, flexible covering material for finishing the surface of a building consists of a matrix layer covered with a water-curable composition consisting essentially of a cement mix and a polymeric binder therefor.
Patent CA-1051571-A (CA)
Inventor: KREUDER HANS J
IPC: C08L21/00
Filed: 1975-07-22
Granted: 1979-03-27
Abstract: NITROCELLULOSE ALKYD RESIN LACQUERS                 Abstract of the Disclosure Alkyd resin lacquers which contain cellulose nitric acid esters can be prevented from "lifting" and yellowing by the addition of bis-[hydroxyphenyl]-alkanes which are substituted in the nucleus.
Patent CA-1063323-A (CA)
Inventor: TAKAMATSU IKUO
IPC: A44B19/26
Filed: 1975-09-23
Granted: 1979-10-02
Abstract: ABSTRACT OF THE DISCLOSURE          A slider for us  with a pair of concealed fastener stringers in which rows of scoops are stitched to respective folds formed rearwardly along the opposed longitudinal edges of stringer tapes, in such a manner that each tape fold has a loose outermost edge on the outside of the line of stitching.          A pair of side walls on the marginal edges of the rear wall of the slider body extend from its lower end and terminate short of its upper end, and a pair of outer lips turned inwardly from the side walls extend close to the lipped or flanged inboard end of a separator on the upper end of the rear wall.  The slider of this configuration provide the advance of preventing the jamming of the loose outermost edges of the tape folds as they  enter the guide channel in the slider body during the fastener closing movement of the slider.
Patent CA-1042998-A (CA)
Inventor: VENEZIA J WILLIAM
IPC: H01R13/53
Filed: 1975-11-18
Granted: 1978-11-21
Abstract: Abstract of the Disclosure An electrical connector in which a sleeve-like in-sert of conductive elastomeric material serves as an internal shield, the insert terminating at a rounded end made by folding the wall of the insert upon itself at that end to establish the desired rounded profile contour and to space the terminal edge of the wall away from the rounded end in the direction along the insert toward the other end thereof.
Patent CA-1054059-A (CA)
Inventor: WELSTEAD WILLIAM J JR
IPC: C07D213/57
Filed: 1975-12-23
Granted: 1979-05-08
Abstract: ABSTRACT OF THE DISCLOSURE 1-R-3-Pyrrolidinyl-.alpha.-phenyl-.alpha.-(2-pyridyl)acetamides, -acetonitriles and -methanes represented by the following formula:       wherein R represents lower alkyl, lower cycloalkyl or phenyllower alkyl and Y is carbamoyl, cyano or hydrogen having antiarrhythmic activity are disclosed.  Pharmaceutically acceptable acid addition salts are included as part of the invention.
Patent CA-1061740-A (CA)
Inventor: SEPALL OLA
IPC: C09F3/02
Filed: 1976-01-12
Granted: 1979-09-04
Abstract: ABSTRACT OF THE DISCLOSURE     A process for the continuous purification of crude sulphate turpentine to remove odour and colour in which the crude turpentine product is intensely agitated with an alkali metal or alkaline earth metal hypochlorite in a first reactor vessel having a high speed impeller therein, subsequently subjecting the turpentine-hypochlorite mixture to a high velocity stream of water vapour in a steam ejector and equilibrating the resulting mixture in a second reaction vessel, and finally separating a purified vapour phase containing turpentine from a liquid phase containing impurities.
Patent CA-1060461-A (CA)
Inventor: SANDHACK LOTHAR
IPC: B01J21/00
Filed: 1976-01-14
Granted: 1979-08-14
Abstract: CONTINUOUS PROCESS FOR PRODUCING GAMMA-BUTYROLACTONE   BY CATALYTIC HYDROGEN OF MALEIC ANHYDRIDE              (D#71,200-DTA-100-F) ABSTRACT OF THE DISCLOSURE           A continuous process for producing gamma-butyro-lactone by hydrogenating maleic anhydride in two stages in the presence of a catalyst composed of cobalt oxide and palladium on a support of silica.  The hydrogenation is performed at a hydrogen pressure of 100 to 125 atmospheres and at a temperature of 50 to 100°C. in the first stage and at 190 to 220°C. in the second stage.     -I-
Patent CA-1057861-A (CA)
Inventor: PATTERSON GARVIN W
IPC: G06F13/00
Filed: 1976-02-02
Granted: 1979-07-03
Abstract: ABSTRACT OF THE DISCLOSURE   An input/output processing system includes a plurality of active modules, a plurality of passive modules, at least one memory module and a system interface unit having a plurality of ports, each of which connect to a different one of the modules.  The active modules include an input/ output processing unit which processes interrupts and executes command sequences and a multiplexer unit which directly controls transfers between the memory module and any one of the peripheral devices coupled to different ones of a plurality of ports of the multiplexer unit.  The system interface unit which operatively provides connections between the different modules includes apparatus for generating steering codes defining the physical location of each module requiring service by another module of the system. The system interface unit appends information provided by the particular module generating a request for attention to the steering code generated. The generation of steering code information by the system interface unit and the module included in such requests insures that only authorized accesses are made to the different modules during the input/output process-ing unit's execution of programs during the running of processes associated therewith.
Patent CA-1079951-A (CA)
Inventor: VINCENT GARY A
IPC: C08L83/04
Filed: 1976-02-11
Granted: 1980-06-24
Abstract: Abstract of the Disclosure Improved electrical devices are disclosed such as transformers, and capacitors containing an improved dielectric fluid consisting essentially of a major amount of a liquid polyorganosiloxane and a minor amount of certain selected nitro substituted organic compounds which are soluble in said siloxane.
Patent CA-1072826-A (CA)
Title: Weather-resistant adhesive film
Inventor: MITSUISHI YUKIO
IPC: C09J7/02
Filed: 1976-03-25
Granted: 1980-03-04
Abstract: ABSTRACT OF THE DISCLOSURE      An adhesive film having weatherability comprising (I) a polyethylene terephthalate film base being oriented in at least one direction and having a refractive index, in the orientation direction, of 1.57 to 1.78, a refractive index, in the thickness direction, of 1.48 1.57, a density of 1.340 to 1.390 g/cm3, and a thickness of 5 to 250 microns, and (II) an adhesive layer coated on at least one surface of said film base (I) either directly or through (III) a layer of a thin metallic film.  Or an adhesive film comprising (I), (II) coated on one surface of (I), and (III) coated on the other surface of (I).
Patent CA-1096531-A (CA)
Inventor: BEREJKA ANTHONY J
IPC: C08L33/00
Filed: 1976-04-08
Granted: 1981-02-24
Abstract: A B S T R A C T      Compositions comprising a mixture of an adhesive copolymer of ethylene and a monoolefinically unsaturated polar comonomer. for example, vinyl acetate, in combination with an olefin rubber, preferably a rubbery copolymer of ethylene and propylene, exhibited excellent adhesive properties, particularly when applied to non-porous surfaces such as metals.  Creep resistance can be improved by lightly crosslinking the composition with radiation. Typically thermoplastic in nature, these compositions can be made thermosetting by including in the composition a heat activatable crosslinking system.  The compositions also exhibit a resistance to blocking and flexibility at low temperatures.
Patent CA-1080947-A (CA)
Inventor: PAYNE BOBBY L
IPC: B05D1/18
Filed: 1976-04-20
Granted: 1980-07-08
Abstract: "METHOD OF INSPECTING AND TREATING SUCKER ROD"               ABSTRACT OF THE DISCLOSURE         A continuous process for reclaiming sucker rod which has been used downhole in a borehole. The salvaged rod is degreased, visually inspected, subjected to a shot peening operation, analyzed for structural imperfections, imparted with a protective coating which includes an inhibiting agent, and stored for subsequent use.
Patent CA-1048207-A (CA)
Inventor: KOIDE YOOICHI
IPC: C09K3/10
Filed: 1976-05-06
Granted: 1979-02-13
Abstract: ABSTRACT OF THE DISCLOSURE            A fire-retardant intumescent putty comprising (a) at least 4% by weight of a liquid or semi-solid organic material having a viscosity of 50-100,000 c.st. at 210°F, and (b) at least 13% by weight of a phosphoric acid represented by the formula;     (xH2O-yP2O5)n wherein  0<? ?3, n= 1-14) whose one or all of the hydrogen atoms are substituted with a mono-, di- or trivalent nitrogen-containing group such as NH? , NH3 etc. is disclosed.          The putty has excellent airtightness and smoke tightness under normal and fire exposure conditions, and bubbles up when heated with flame, producing a foamed carbonaceous layer having out-standing fire-retardation.