baber/WOPTO huggingface dataset:
Patent SG-183375-A1 (SG)
Title: Fragments of the pa subunit of rna dependent rna polymerase from pandemic influenza virus a 2009 h1n1, and their use
Inventor: CUSACK STEPHEN
IPC: G16B15/30
Filed: 2011-03-15
Abstract: The present invention relates to polypeptide fragments comprising an amino-terminal fragment of the PA subunit of a viral RNA-dependent RNA polymerase possessing endonuclease activity, wherein said PA subunit is from Influenza A 2009 pandemic HlNl virus or is a variant thereof. This invention also relates to (i) crystals of the polypeptide fragments which are suitable for structure determination of said polypeptide fragments using X-ray crystallography and (ii) computational methods using the structural coordinates of said polypeptide to screen for and design compounds that modulate, preferably inhibit the endonucleolytically active site within the polypeptide fragment. In addition, this invention relates to methods identifying compounds that bind to the PA polypeptide fragments possessing endonuclease activity and preferably inhibit said endonucleolytic activity, preferably in a high throughput setting. This invention also relates to compounds which are able to modulate, preferably to inhibit, the endonuclease activity of the PA subunit polypeptide fragment or variant thereof of the present invention and pharmaceutical compositions comprising said compounds for the treatment of disease conditions caused by viral infections with viruses of the Orthomyxoviridae family, Bunyaviridae family and/or Arenviridae family, preferably caused by viral infections with Influenza A 2009 pandemic HlNl virus. Preferably, said compounds are identifiable by the methods disclosed herein or said pharmaceutical compositions are producible by the methods disclosed herein.
Patent SG-184935-A1 (SG)
Title: Chemosensory receptor ligand-based therapies
Inventor: BARON ALAIN
Filed: 2010-10-19
Abstract: Provided herein are methods for treating diabetes, obesity, and other metabolic diseases, disorders or conditions comprising chemosensory receptor ligands. Also provided herein are chemosensory receptor ligand compositions and the preparation thereof for the methods of the present invention.
Patent SG-185375-A1 (SG)
Title: Method and apparatus for providing a charge blocking layer on an infrared up-conversion device
Inventor: SO FRANKY
Filed: 2011-05-24
Abstract: Embodiments of the invention are directed to an improved device for sensing infrared (IR) radiation with upconversion to provide an output of electromagnetic radiation having a shorter wavelength than the incident IR radiation, such as visible light. The device comprises an anode, a hole blocking layer to separate an IR sensing layer from the anode, an organic light emitting layer that is separated from the anode by the IR sensing layer, and a cathode. The hole blocking layer assures that when a potential is applied between the anode and the cathode the organic light emitting layer generates electromagnetic radiation only when the IR sensing layer is irradiated with IR radiation.
Patent SG-186228-A1 (SG)
Title: Urea derivatives and their therapeutic use in the treatment of, inter alia, diseases of the respiratory tract
Inventor: WOO CHI-KIT
Filed: 2011-06-09
Abstract: Compounds of formula (I) are p38 MAPK inhibitors, useful as anti- inflammatory agents in the treatment of, inter alia, diseases of the respiratory wherein R1 is a radical of formula (IA) or (IB) or (IC): 10 Y is -0- or -S(0)p- wherein p is 0, 1 or 2; A is an optionally substituted cycloalkylene radical having 5, 6 or 7 ring atoms fused to a phenyl ring; and R2, R3b and R4b are as defined in the claims.
Patent SG-189185-A1 (SG)
Title: Production of alkenes by combined enzymatic conversion of 3-hydroxyalkanoic acids
Inventor: MARLIERE PHILIPPE
Filed: 2011-10-18
Abstract: The present invention relates to a method for generating alkenes through a biological process. More specifically, the invention relates to a method for producing alkenes (for example propylene, ethylene, 1-butylene, isobutylene or isoamylene) from molecules of the 3-hydroxyalkanoate type.
Patent SG-189960-A1 (SG)
Title: Process for making a high viscosity base oil with an improved viscosity index
Inventor: ELOMARI SALEH
Filed: 2011-07-21
Abstract: We provide a process, comprising oligomerizing one or more olefins having a boiling point less than 82°C in a presence of an ionic liquid catalyst and one or more C5+ alpha olefins in a reactor to produce a base oil having a kinematic viscosity at 100C of 36 mm2/s or higher and a VI greater than 55; and wherein the one or more olefins having the boiling point less than 82°C comprise greater than 50 wt% of a total mixture of olefins fed to the reactor. We provide a process, comprising oligomerizing olefins having a low boiling point in a presence of an ionic liquid catalyst and a mixture of C5+ alpha olefins derived from waste plastic to produce a base oil having a kinematic viscosity at 40°C greater than 1100 mm2/s and a VI greater than 55. We also provide a base oil made by the process.
Patent SG-190991-A1 (SG)
Title: [((1r,2s,5r)-2-isopropyl-5-methyl-cyclohexanecarbonyl)-amino]-acetic acid isopropyl ester and related compounds and their use in therapy
Inventor: WEI EDWARD TAK
Filed: 2011-04-04
Abstract: The present invention pertains generally to the field of coolants and medical therapy. More particularly, the present invention relates to certain anti-nociceptive agents, such as [((1R,2S,5f?)-2-isopropyl-5-methyl-cyclohexanecarbonyl)-amino]-acetic acid isopropyl ester, that are potent and long-acting and selectively cooling for non-keratinized epithelial tissues as compared to keratinized epithelial tissues, and are useful, for example, for the treatment of (e.g., the alleviation of symptoms of; the amelioration of) sensory discomfort of non-keratinized stratified epithelial (NKSE) tissue; and so for treatment of: sensory discomfort of an ocular surface, an eyelid, a margin of an eyelid, an anterior part of an eyeball, a conjunctiva, a lachrymal system, a pre-corneal film, or a cornea, a lining of the oral cavity, an internal portion of the lips, a pharyngeal surface, an esophageal surface, or an anogenital surface; eye discomfort, e.g., caused by extended wear of contact lenses, by eye strain and/or fatigue, by air pollutants, by excessive exposure to the sun, by conjunctivitis, by dry eye syndrome; sensory discomfort associated with oral mucositis; airway (e.g., larynx, trachea, and/or bronchi) tightness, discomfort in the airways (e.g., larynx, trachea, and/or bronchi), choking, cough, and/or dyspnea, e.g., associated with asthma and/or chronic obstructive pulmonary diseases (COPD).
Patent SG-192145-A1 (SG)
Title: System for treating ballast water in ballast tanks
Inventor: HUMMER JAN STUMPE
Filed: 2012-03-05
Abstract: A system for treating ballast water in ballast tanks (1) onboard vessels and offshore constructions, said system (20) comprising: one or more ballast tanks (1 ), a circulation pump (22) capable of circulating or recirculating, via a tubing, ballast water from and to the one or more ballast tanks (1); a gas supply unit (21 ) which is connected to the tubing (22) on the delivery side of the recirculation pump (22) in such a manner that gas, such as air and/or inert gas such as nitrogen and/or carbon dioxide can be supplied to the ballast water; and one or more nozzle heads (28) that are functionally connected to the tubing and is/are arranged in one or more ballast tanks (1), said one or more nozzle heads comprising at least one nozzle for injection of the gas-containing water into the one or more ballast tanks (1); a device (37) configured for removing and/or killing live organisms in the ballast water.
Patent SG-192600-A1 (SG)
Title: Combinations comprising macitentan for the treatment of glioblastoma multiforme
Inventor: REGENASS URS
Filed: 2012-02-03
Abstract: The invention relates to the use of macitentan in combination with a cytotoxic therapy agent (such as temozolomide or paclitaxel), with radiotherapy or with both a cytotoxic therapy agent and radiotherapy, in the treatment of malignant glioma, in particular glioblastoma multiforme.
Patent SG-194660-A1 (SG)
Title: Treatment of bisphenol-a residue streams
Inventor: PALMER DAVID
Filed: 2012-06-04
Abstract: In a method of treating a residue stream from the production of bisphenol-A, the residue stream is contacted with an aqueous solution of a base under conditions effective to hydrolyze at least part of said residue stream into acetone and phenol and produce an effluent stream. Acetone is recovered from the effluent stream to produce a phenol-containing mixed phase stream which is substantially free of acetone and which contains water and unhydrolyzed heavy organic compounds. The phenol-containing mixed phase stream is then treated with a water-immiscible organic solvent to extract phenol and unhydrolyzed heavy organic compounds into said solvent and produce an organic phase containing the solvent, phenol and unhydrolyzed heavy aromatic compounds and an aqueous phase with reduced concentrations of phenol and unhydrolyzed heavy organic compounds. At least part of the phenol and the organic solvent are subsequently recovered from the organic phase.
Patent SG-194734-A1 (SG)
Title: Solar energy converter
Inventor: SOON CHOON SEN
IPC: F24S10/50
Filed: 2012-02-08
Abstract: According to one aspect, there is provided a solar energy converter, including: a lens; a base plate having a first surface that faces the lens and a second surface that is opposite to the first surface; and a solar cell sandwiched between the lens and the base plate, wherein both the lens and the base plate are each provided with at least one channel for fluid for cooling the solar cell. Also contemplated is provision of at least one fin on both the lens and the base plate for cooling the solar cell. According to a second aspect, there is provided a method for cooling a solar energy converter having a lens, a base, and at least one solar cell sandwiched between said lens and said base plate, the method comprising the step of: cooling the at least one solar cell on two opposing sides.
Patent WO-2022025819-A1 (WO)
Inventor: LIN WUJUAN
IPC: G05D23/30
Filed: 2020-07-27
Abstract: There is provided a method of controlling an air-conditioning and/or heating system in a region within a building. The method includes: obtaining occupancy information for a region at a current time; determining future occupancy information for the region with respect to a subsequent time based on the occupancy information; obtaining future weather information for the region with respect to the subsequent time; and determining common thermal comfort preference information with respect to occupants in the region with respect to the subsequent time based on the future weather information and the future occupancy information. There is also provided a corresponding system for controlling an air-conditioning and/or heating system in a region within a building.
Patent WO-2023191727-A1 (WO)
Inventor: CHOOLANI VINITA
IPC: A23L15/00
Filed: 2023-03-31
Abstract: The present invention is directed to plant-based vegan egg compositions and methods of producing such compositions. More particularly, the invention provides a plant-based vegan simulated tamagoyaki composition comprising tofu, flour, water, plant-based protein, Japanese sweet sauce (Mirin), natural yellow food colouring, double-acting baking powder, sugar and a gum and a) salt; or b) modified starch, methylcellulose and soya sauce.
Patent WO-2014070119-A1 (WO)
Title: Dispositif combiné laser ophtalmique
Inventor: DOLZAN ALES
IPC: A61F9/008
Filed: 2013-10-29
Abstract: La présente invention porte sur un dispositif laser pour chirurgie de l'œil utilisé par des ophtalmologistes dans le traitement de capsulotomie et d'iridotomie, et un dispositif pour trabéculoplastie laser sélective. L'essence du dispositif combiné laser ophtalmique de la présente invention repose sur le fait qu'il a un unique laser ayant un axe optique pour les deux longueurs d'onde ; la longueur d'onde basique de 1 064 nm et la longueur d'onde à fréquence doublée de 532 nm. Le passage entre les deux longueurs d'onde est réalisé par un commutateur d'orientation de polarisation. Le doublage de fréquence est inactif à la longueur d'onde de 1 064 nm et il est actif pour la longueur d'onde de 532 nm. A la longueur d'onde de 532 nm, des éléments optiques supplémentaires pour atténuation et collimation de l'impulsion laser sont mis en marche.
Patent WO-2022081096-A1 (WO)
Inventor: KOVAC GREGOR
IPC: A61F13/20
Filed: 2021-10-01
Abstract: L'invention concerne un tampon (1) hygiénique à maintien de forme, physiologiquement acceptable et biologiquement dégradable, qui convient à l'insertion dans une cavité corporelle de chaque utilisateur. Le cœur fibreux absorbant du tampon (1) est formé en soumettant une ébauche (2) à la compression radiale afin de former des rainures (11, 12) longitudinales et des nervures (13) qui sont localisées entre lesdites rainures (11, 12) sur la surface du tampon (1), ledit tampon (1) étant exclusivement constitué de fibres végétales naturelles et biologiquement décomposables. Le tampon (1) est constitué de ladite ébauche comprimée radialement dans plusieurs directions (2), qui est constituée de multiples couches de bandes fibreuses (21, 22, 23), qui sont enroulées autour d'un axe géométrique (200) et dans lequel, avant ladite compression radiale de l'ébauche (2), une pluralité de rainures (201, 202, 203) est imprimée dans son sens circonférentiel, qui sont chacune en soi en profil en forme de lettre V ou U et s'étendent circonférentiellement et sont convenablement espacées l'une de l'autre dans le sens transversal de la bande fibreuse, à savoir dans le sens longitudinal de l'ébauche (2) et le long dudit axe géométrique (200), lesdites rainures (201, 202, 203) étant imprimées dans lesdites couches de bandes fibreuses (21, 22, 23) au moins jusqu'à une mesure telle que les fibres de chaque couche supérieure (21) de bande fibreuse sont imprimées vers les fibres de chaque couche (22) située en-dessous de ladite couche supérieure (21) et entrelacées avec cette dernière. Grâce à une telle conception, le maintien de forme du tampon (1) est garanti non seulement sous l'état sec avant l'utilisation, mais également sous son état humide durant l'utilisation, également le décollement non souhaité des couches du tampon (1) ou même le maintien des parties du tampon (1) à l'intérieur d'une cavité corporelle par le retrait du tampon (1) après l'utilisation est entièrement évité.
Patent WO-2021040630-A1 (WO)
Inventor: IMABEPPU KENGO
IPC: B60J5/00
Filed: 2019-08-28
Abstract: Disclosed is a sensor device for use in a vehicle having a door. The sensor device comprises a first module (111) configured to detect at least one object in the vicinity of the vehicle and a second module (112) configured to detect an action of a user in the vehicle, and a controller (120) configured to control an output module (130) based on the detection of the first module (111) and the detection of the second module (112), wherein if the at least one object is detected and the action of the user is detected, the controller (120) controls the output module (130) so as to prevent the user from existing via the door.
Patent TN-2010000337-A1 (TN)
Title: Tricyclic compounds having corticotropin-releasing factor antagonistic activity and pharmaceutical compositions containing them
Inventor: ASO KAZUYOSHI
IPC: C07D498/04
Filed: 2010-07-19
Abstract: There is provided a compound of the formula (l') : wherein X is a nitrogen or CRx, Rx is a hydrogen, etc., R1 is an optionally substituted hydrocarbon group, etc., R2 is an optionally substituted hydrocarbon group, etc., ring A is 5- to -8-membered heterocyclic ring, etc., and each of y1,. y2 and y3 is an optionally substituted carbon or a nitrogen, etc.; or 'a salt thereof or a prodrug thereof., which have CRF receptor antagonistic activity and use thereof
Patent TN-2010000560-A1 (TN)
Title: Process for the treatment of the aqueous stream coming from the fischer -tropsch reaction by means of ion exchange resins
Inventor: MIGLIO ROBERTA
IPC: C02F1/42
Filed: 2010-12-03
Abstract: Process for the treatment of the aqueous stream coming from the Fischer-Tropsch reaction comprising : feeding the aqueous stream containing the organic by products of the reaction to a distillation or stripping column ; separation from the column of an aqueous stream enriched in alcohols having from 1 to 8 carbon atoms and other possible volatile compounds ; feeding the aqueous stream containing the organic acids leaving the bottom of the distillation column to an ion exchange step wherein said aqueous stream is put in contact with an anionic exchange resin bed and the production of two outgoing aqueous streams : an aqueous stream (i) enriched in organic acids having from 1 to 8 carbon atoms ; a purified aqueous stream (ii) with a low content of organic acids.
Patent TN-2013000160-A1 (TN)
Title: Crystalline forms of hydrochloride salt of (4a-r,9a-s) -1- (1h - benzoimidazole- 5 -carbonyl) -2, 3, 4, 4a, 9, 9a - hexahydro -1h- indeno [2, 1 -b] pyridine- 6 -carbonitrile and their use as hsd 1 inhibitors
Inventor: ECKHARDT MATTHIAS
IPC: C07D401/06
Filed: 2013-04-12
Abstract: The present invention relates to crystalline compounds of the following structural formula (II) possessing valuable pharmacological activity. Particularly, the compounds are inhibitors of 11 â-hydroxysteroid dehydrogenase (HSD) 1 and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme, such as metabolic diseases, in particular diabetes type 2, obesity, and dyslipidemia.
Patent TN-2016000057-A1 (TN)
Title: Methods of treating sporadic inclusion body myositis
Inventor: GLASS DAVID
IPC: C07K16/28
Filed: 2014-08-13
Abstract: The disclosure relates to the treatment of sporadic inclusion body myositis and other muscle wasting disorders with navel regimens, which employ a therapeutically effective amount of a myostatin antagonist, e.g., a myostatin binding molecule, e.g., a myostatin antibody or an ActRI 1 receptor binding molecule, an ActRI 1 receptor antibody, such as the bimagrumab antibody.
Patent WO-2005059428-A1 (WO)
Title: Tubes ondules fabriques a partir d'un materiau a base de plastique combine a un procede de soudage par electro-fusion
Inventor: ZENGIN ZEKARIYA
IPC: F16L25/00
Filed: 2004-12-17
Abstract: La présente invention concerne un tube ondulé combiné à un procédé d'électro-fusion, qui comprend une partie ergot/partie mâle (2) fabriquée à partir d'un matériau à base de plastique et une partie manchon/femelle (1) et une formation de nervures (5), qui est réalisée au niveau de la périphérie le long de la surface extérieure de la région du corps (4) située entre cette partie ergot (2) et cette partie manchon (1) et, qui est composé de fente d'indentation/nervure (6) et de saillies et, qui se caractérise en ce que la partie ergot (2) et la partie manchon (1) entrant dans la partie ergot (2), l'organe de mélange (9) assurant l'électro-fusion étant fourni entre ces deux parties, comprend un angle prédéterminé de forme conique
Patent WO-2010104482-A1 (WO)
Title: Système de contrôle de la qualité du mazout destiné aux stations d'essence
Inventor: TUNALI OZGUR
IPC: G06Q30/00
Filed: 2009-11-24
Abstract: Cette invention se rapporte à un système de contrôle de la qualité du mazout qui fournit des résultats de tests effectués sur des échantillons de mazout prélevés dans des stations d'essence et menés à bien au moins par un laboratoire et/ou par des dispositifs de contrôle de qualité installés sur les réservoirs à l'endroit où le mazout est stocké dans les stations d'essence, à un consommateur, indépendamment des compagnies de distribution. Ce système se compose d'au moins un module d'interprétation (7) qui contient des valeurs de référence et qui compare les résultats d'analyse du mazout reçus en provenance d'un laboratoire et/ou de dispositifs de contrôle aux valeurs de référence et conclut si le mazout est de qualité ou non, puis les données interprétées sont transmises au consommateur par l'intermédiaire d'au moins un indicateur de résultats de tests (8) sur le site de la station d'essence, indépendamment des compagnies de distribution.
Patent WO-2011078826-A1 (WO)
Title: Présentoir pliant destiné à des produits
Inventor: KABAKCI MUSTAFA
IPC: A47F5/11
Filed: 2010-12-22
Abstract: L'invention concerne un présentoir pliant léger, qui peut être facilement assemblé avec de faibles coûts de production et de main-d'oeuvre. Ce présentoir se compose de parties à base de carton, de caoutchouc ou de plastique, qui peuvent être facilement montées et démontées, et s'utilise pour présenter des articles de type et de taille variés dans des centres commerciaux, des supermarchés, des magasins, des foires, etc.
Patent WO-2017116373-A1 (WO)
Title: Mode de réalisation de caravane comprenant une unité rotative
Inventor: OCAL TAHIR
IPC: B60P3/34
Filed: 2016-12-28
Abstract: Mode de réalisation de caravane (A) pouvant être intégré à des véhicules à moteur et à des véhicules non motorisés (1) et à des constructions fixes pour un hébergement en camping, caractérisé en ce qu'il comporte une unité principale (4) et une unité mobile rotative (2) qui peut tourner à l'intérieur de ladite unité principale (4).
Patent WO-2020263206-A1 (WO)
Inventor: KIRAZ ALPER
IPC: G01N33/48
Filed: 2020-06-17
Abstract: The present invention relates to a three dimensional (3D) microfluidic cartridge (1) which is suitable for reproduction of cells therein and for observing angiogenesis process. The microfluidic cartridge (1) of the present invention is characterized by side area (3) the height of which is greater than the height of the central area (2). With the microfluidic cartridges present in this invention, three dimensional (3D) cell culture will be carried out, tumor spheroids will be formed in the said platforms, and the angiogenesis potentials of these spheroids will be measured. In addition to this, the responses of endothelial cells against angiogenic or antiangiogenic effects of various small molecules, drugs, and protein therapeutics will be measured in this system.
Patent WO-2022125010-A1 (WO)
Title: Upper room air sterilization system with uvgi content
Inventor: REGONESI GIULIANO
IPC: F24F8/22
Filed: 2020-12-11
Abstract: The invention is related to UVGI rays using air sterilization system that is used for sterilization, cleans the air, is easy to use, has low cost and energy consumption, is comprised of UV-C LEDs (1) that can be adjusted according to the requirements, illuminating ray (2), fan (3), panel (4) and hanger (5) parts.