Patent SG-11201901402P-A (SG)
Title: Pharmaceutical Composition for Delivery of Peptide
Inventor: GSCHLIESSER SIEGFRIED
IPC: A61K31/00
Filed: 2018-09-19
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 28 March 2019 (28.03.2019) WIPO I PCT 11111111111111011111111111111110111110100111111111111111111111111110011111011110111111 (10) International Publication Number WO 2019/058273 Al (51) International Patent Classification: A61K 31/00 (2006.01) (21) International Application Number: PCT/[132018/057209 (22) International Filing Date: 19 September 2018 (19.09.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 201711033555 21 September 2017 (21.09.2017) IN (71) Applicant: ANYA BIOPHARM INC. [CN/CN]; 6F., No. 378, Changchun Rd., Taipei, 10487 (TW). (72) Inventors; and (71) Applicants: GSCHLIESSER, Siegfried [AT/CN]; 8F., No.16-6, Fuzhou St., Zhongzheng Dist., Taipei City, 100 (TW). DESAI, Bhushan Dhruvkumar [IN/IN]; Lodha Aqua, Antartica C-304 Mira Road East, Thane, Maharash- tra 401107 (IN). (74) Agent: KHURANA & KHURANA, ADVOCATES & IP ATTORNEYS; E-13, UPSIDC, Site-IV, Behind-Grand Venice, Kasna Road, Greater Noida, National Capital Re- gion, Uttar Pradesh 201310 (IN). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) in black and white; the international application as filed contained color or greyscale and is available for download from PATENTSCOPE -0!C N oc O O C (54) Title: PHARMACEUTICAL COMPOSITIONS FOR DELIVERY OF PEPTIDE (57) : The present invention relates to a pharmaceutical composition including: a pharmaceutically effective amount of at least one peptide; and a pharmaceutically acceptable amount of a combination of: (a) at least one metal in form of any or a combination of a salt thereof and a complex thereof; and (b) at least one reducing agent, wherein, the at least one metal is selected from any or a combination of: vanadium, chromium and manganese, and wherein the combination of (a) at least one metal in form of any or a combination of a salt and a complex and (b) at least one reducing agent affords protection, at least in part, to the at least one peptide from proteolytic degradation upon ingestion thereof.