baber/WOPTO huggingface dataset:
Patent CA-2629777-A1 (CA)
Inventor: CLOSE JOSHUA
IPC: C07D491/10
Filed: 2006-11-17
Abstract: The present invention relates to a novel class of substituted spirocyclic compounds, represented by the following structural Formula: I Wherein A, B and D are independently selected from CR1 2, NRla, C(O) and O; E is selected from a bond, CR1 2. NR1 a, C(O) and O; wherein at least one of A, B, D or E is CR1 2; and provided that when A is O, then E is not O; G is CRl 2; R is selected from NH2 and OH; These compounds can inhibit histone deacetylase and are suitable for use in selectively inducing termin differentiation, and arresting cell growth and/or apoptosis of neoplastic cells, thereby inhibiting proliferation of such cells. Thus, the compounds of the present invention are useful in treating a patient having a tumor characterized by proliferation of neoplastic cells. The compounds of the invention may also be useful in the prevention and treatment of TRX-mediated diseases, such as autoimmune, allergic and inflammatory diseases, and in the prevention and/or treatment of diseases of the central nervous system (CNS), such as neurodegenerative diseases. The present invention further provides pharmaceutical compositions comprising the compounds of the instant invention and safe dosing regimens of these pharmaceutical compositions, which are easy to follow, and which result in a therapeutically effective amount of these compounds in vivo.
Patent CA-2631575-A1 (CA)
Inventor: MUKKAVILLI KRISHNA KIRAN
IPC: H04L27/26
Filed: 2007-01-03
Abstract: Methods and apparatus for noise estimation in a communication system. In an aspect, a method for noise and interference estimation is provided. The method includes identifying one or more unmodulated subcarriers in a received waveform, processing the one or more unmodulated subcarriers to produce a demodulated output, and determining a noise variance based on the demodulated output. In another aspect, an apparatus for providing a noise and interference estimation is provided. The apparatus includes selection logic configured to identify one or more unmodulated subcarriers in a received waveform, a processor configured to demodulate the one or more unmodulated subcarriers to produce a demodulated output, and variance determination logic configured to determine a noise variance based on the demodulated output.
Patent CA-2632291-A1 (CA)
Title: Computer gaming device and method for computer gaming
Inventor: BURNSIDE ROBERT S
IPC: A63F13/00
Filed: 2006-10-04
Abstract: A system for computer gaming includes a processor configured to provide a first table of a first group of players grouped together to play a first hand and provide to each of the first group of players one or more cards for the first hand. The system includes an interface couple to the processor and configured to receive from a first player of the first group of players a request to fold the one or more cards of the first player. The processor is also configured to automatically move the first player to a second table of a second group of players grouped together to play a second hand.
Patent CA-2633457-A1 (CA)
Title: Heterocyclic amide derivatives as calcium channel blockers
Inventor: PAJOUHESH HASSAN
IPC: C07D405/06
Filed: 2006-12-19
Abstract: Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted N-type or T-type calcium channel activity are disclosed. Specifically, a series of heterocyclic amides are disclosed of the general formula (I) where Z is N  or CHNR2 and X is NR2, O, S, S=O or SO2. Among other definitions for R, R1, W and Y, the compounds of formula (1) are further characterized by at least one of W or Y being CR3Ar2 where Ar is an aromatic or heteroaromatic ring
Patent CA-2634180-A1 (CA)
Title: An improved remote control for home entertainment
Inventor: TUOMY JAMES M
IPC: G08C19/00
Filed: 2006-12-07
Abstract: A remote control system is provided that includes a master controller for storing a plurality of remote control codes for a plurality of remotely controlled equipment, receiving a remote control code request message, retrieving a requested remote control code and transmitting the requested remote control code, and a remote control unit for transmitting the remote control code request message, receiving the requested remote control code from the master controller, storing the requested remote control code, converting the remote control code into a plurality of remote control commands and transmitting at least one of the plurality of remote control commands to at least one of the plurality of remotely controlled equipment, wherein each remote control code contains the plurality of remote control commands for controlling at least one of the plurality of remotely controlled equipment.
Patent CA-2636094-A1 (CA)
Title: Mounting structure of semiconductor optical element
Inventor: YAMAZAKI HIROYUKI
IPC: H01S5/14
Filed: 2008-06-25
Abstract: To provide a mounting structure of a semiconductor optical element, in which structure the turning of a refractive index matching gel is prevented. There is provided a mounting structure of a light emitting element, in which structure signal light emitted from one end of an SOA  2 with phase control mounted to a PLC platform 1 with an optical waveguide la formed therein is made incident on the optical waveguide la and is then again made incident on the SOA 2 with phase control to be emitted from the other end of the SOA 2, wherein the SOA 2 with phase control is mounted to the PLC platform 1 in a state where the other end of the SOA 2 with phase control is projected from the PLC  platform 1, and wherein a refractive index matching gel 3 is arranged between the one end of the SOA 2 with phase control and the optical waveguide 1a.
Patent CA-2637009-A1 (CA)
Title: Container/lid combination for storing food and other articles
Inventor: HICKMAN RALPH R
IPC: B65D43/03
Filed: 2007-02-15
Abstract: A system for aiding the visual matching of containers having diverse openings with matching lids includes affixing, such as by molding or embossing, geometric planar patterns on the bottom walls of a plurality of rectangular containers having different sized openings and affixing the same geometric patterns to the top wall of the matching lids.
Patent CA-2637668-A1 (CA)
Title: Procede continu et appareil de dessalement de marinades
Inventor: BACON ROD
IPC: A23L19/20
Filed: 2007-03-28
Abstract: La présente invention concerne un procédé continu et un appareil pour dessaler des marinades. Le procédé consiste à transporter des marinades ayant un certain contenu en sel le long d'un parcours ; pulvériser de l'eau sur les marinades tandis qu'elles sont transportées le long du parcours, l'eau étant fournie dans une quantité suffisante pour saturer les marinades et déplacer une partie du sel contenu dans celles-ci ; collecter l'eau qui s'égoutte des marinades saturées ; et mesurer le contenu en sel de l'eau collectée afin de surveiller le procédé et déterminer quand le procédé de dessalement est terminé.
Patent CA-2642189-A1 (CA)
Title: Mannose derivatives for killing tumor cells
Inventor: MATHER JOHN
IPC: A01N43/04
Filed: 2007-02-26
Abstract: A method for treating cancer by killing selected tumor cells such as human breast, non-small cell lung cancer cells, pancreatic cancer cells, osteosarcoma cancer cells, and glioblastoma cells, includes administering to a patient in need of treatment, an effective amount of at least one mannose analog such as 2-DG or 2-FM or 2-CM. The killing is believed to be due to an interference with glycosylation. A theranostic method includes determining whether a patient. cancer tumor sample comprises cells sensitive to killing to at least one mannose analog due to an interference with glycosylation.
Patent CA-2645404-A1 (CA)
Title: Dynamic code update
Inventor: RICHARDS ANDREW
IPC: G06F9/445
Filed: 2008-11-28
Abstract: The present application describes techniques for making changes to the code of a computer program. In particular, the present application describes techniques for updating and/or replacing program code dynamically, i.e. whilst the program is executing.
Patent CA-2646432-A1 (CA)
Title: Intelligent incoming message notification
Inventor: SELIGMANN DOREE DUNCAN
IPC: H04M1/72457
Filed: 2003-06-25
Abstract: An intelligent message notification system and method is provided. A signal is received at a telecommunications terminal. The method involves determining whether to notify the user of the terminal of the arrival of the signal based on the semantic content of the signal and the calendrical time at the terminal.
Patent CA-2650920-A1 (CA)
Inventor: ZDEBLICK MARK
IPC: G16H10/60
Filed: 2007-05-02
Abstract: L'invention concerne des méthodes, des systèmes et des compositions qui permettent de traiter un patient selon un régime thérapeutique personnalisé pour un patient. Les modes de réalisation de l'invention consistent à obtenir des informations d'administration de dosage d'un patient et à utiliser ces informations pour produire un régime thérapeutique adapté au patient. Des modes de réalisation de l'invention consistent en outre à préparer et à fournir au patient des dosages physiques pharmaceutiques basés sur le régime thérapeutique personnalisé.
Patent CA-2652393-A1 (CA)
Inventor: SIRRENBERG CHRISTIAN
IPC: A61K31/44
Filed: 2007-04-20
Abstract: L'invention concerne de nouveaux dérivés de 1,5-diphénylpyrazole de formule (I) dans laquelle R1 àR6 ont les significations indiquées dans la revendication 1. Ces nouveaux dérivés sont des inhibiteurs de HSP90 et peuvent être utilisés pour produire un médicament destiné à traiter des maladies dans lesquelles l'inhibition, la régulation et/ou la modulation de HSP90 jouent un rôle.
Patent CA-2653717-A1 (CA)
Title: Methods for site-specific pegylation
Inventor: DONG ZHENG XIN
IPC: C07K16/00
Filed: 2007-05-25
Abstract: The present invention relates to methods for the chemo-selective pegylation of the cysteine residue having unoxidized sulfhydryl side-chain and free .alpha.-amino group in proteins, peptides and other molecules. Similar methods are provided for the chemo- selective pegylation of the homocysteine, selenocysteine, penicillamine, and N-methyl- cysteine residues.
Patent CA-2656106-A1 (CA)
Title: Flush valve
Inventor: JOHNSON DWIGHT N
IPC: E03D3/06
Filed: 2007-07-05
Abstract: Tilting of a main valve assembly under high inlet pressure conditions is prevented by supporting the main valve assembly with housing rib engaging a skirt on the main valve guide tube. Pilot valve opening results from contact of an enlargement on the pilot valve stem with the push rod as the pilot valve begins its upward movement. An off center baffle compensates for the pressure pattern resulting from the side entry inlet. Throttling structure provided by a skirt on the guide tube cooperating with a shoulder in the outlet passage provides a desirable large flush flow. The inlet and handle openings in the valve body include bosses adjacent thereto an internal to the housing.
Patent CA-2658989-A1 (CA)
Title: Tripterygium wilfordii preparations and uses thereof
Inventor: TAO XE-LIEN
IPC: A61K36/00
Filed: 1996-09-27
Abstract: The present invention provides for the use of Tripterygium Wilfordii Hook F  extracts and purified components thereof in the treatment of inflammation or an immune disorder with concomitant lack of steroidal effect. Extracts of this plant (T2) bound to the glucocorticoid receptor and competitively inhibited glucocorticoid mediated cellular processes, such as dexamethasone binding to the glucocorticoid receptor, glucocorticoid mediated activation of target genes, dexamethasone dependent cellular growth, with concomitant inhibition of cyclooxygenase-2 induction and inflammatory processes such as the production of prostaglandin E2. The T2 extract components triptolide and tripdiolide were effective inhibitors. The particular advantage provided by the methods herein is the treatment or prevention of inflammation and the concomitant lack of steroidal agonist effects and NSAID side effects. Conditions treatable by the present methods include inflammation and immune disorders including autoimmune disease.
Patent CA-2661217-A1 (CA)
Inventor: YAMAUCHI YASUHIRO
IPC: H01L31/076
Filed: 2007-08-06
Abstract: A photoelectric converter satisfying both high photoelectric conversion efficiency and high productivity, and its fabrication method. The photoelectric converter (90) has a substrate with a transparent electrode where a transparent electrode layer (2) is provided on a transparent insulating substrate (1), and at least a photoelectric conversion layer (92) principally comprising a crystalline silicon based semiconductor and a backside electrode layer (4) that are formed sequentially on the transparent electrode layer (2) side of the substrate with a transparent electrode. The transparent electrode layer (2) on the substrate with a transparent electrode has a surface shape where large and small protrusions and recesses coexist and spectral haze rate is 20% or above at the wavelength of 550-800 nm. The photoelectric conversion layer principally comprising the crystalline silicon based semiconductor has a film thickness of 1.2-2 µm, and a Raman ratio of 3.0-8Ø
Patent CA-2664594-A1 (CA)
Inventor: SMITH STEPHEN WILLIAM
IPC: B62J25/00
Filed: 2007-09-28
Abstract: The present invention provides a leg support for a motorcycle and/or bike including a support member, a body portion and at least one securing means for securing said body portion and/or support member to the motorcycle, whereby the leg support provides a means of assisting a person to hold their body in a forward position while riding.
Patent CA-2665969-A1 (CA)
Inventor: BJOERKLUND MAGNUS
IPC: D21C9/14
Filed: 2007-09-06
Abstract: The present invention relates to a process of bleaching pulp derived from an alkaline pulping process having a hexenuronic acid content prior to the final bleaching stage from about 1 to about 80 mmol/kg dry pulp, said process comprising three chlorine 5 dioxide stages D0, D1, and D2, wherein the chlorine dioxide charges based on the total chlorine dioxide charge in a) D0 is from about 40 to about 60 %; b) D1 is from about 30 to about 55 %; c) D2 is from about 4 to about 20 %, and wherein the final chlorine dioxide stage D2 is 10 performed at a pH from about 2 to about 4.5. The invention also relates to a bleached pulp obtainable by the process.
Patent CA-2666569-A1 (CA)
Inventor: OLIVER MATTHEW
IPC: A61M1/14
Filed: 2009-05-26
Abstract: A server device, and related systems and methods for managing dialysis patient information. The patient information includes information relating to stages of data collection including baseline characteristics, eligibility for treatment modalities, and outcomes. A remote terminal is configured for displaying in the remote terminal a first user interface for receiving the patient information for the subject patient. The server is configured to receive from the remote terminal the patient information for the subject patient and store said patient information in a patient record in the memory, and determine, based on medical logic rules, whether the patient information is consistent with the patient record in order to proceed to a next stage of data collection, and if so permitting displaying in the remote terminal a second user interface for receiving patient information relating to the next stage of data collection.
Patent CA-2668751-A1 (CA)
Title: Adjustable bag retaining apparatus
Inventor: LAITILA TONI
IPC: B65B67/12
Filed: 2009-06-11
Abstract: Provided is an adjustable bag retaining apparatus comprising a hook or clamp, the hook or clamp capable vertically sliding movement on or in a track, mast, stand, support or hollow sleeve for accomodating bags of different sizes for packing.
Patent CA-2675275-A1 (CA)
Inventor: SON ERNEST LEE
IPC: A61B17/32
Filed: 2008-01-11
Abstract: A lancing device including a replaceable multi-lancet cartridge The lancing device includes a drive mechanism an activation mechanism, and an advancing mechanism The advancing mechanism includes a linear-pull slide controls an indexing mechanism, a charger mechanism, and a cap-displacement mechanism The indexing mechanism sequentially advances the lancets to an active position The charger mechanism charges the drive mechanism and removes the lancet caps And the cap-displacement mechanism moves the separated caps from the lancing stroke path The activation mechanism then releases the charged lancet to traverse the lancing stroke path to pierce the subject's skin Some embodiments include an anti-reverse mechanism to prevent reuse of the lancets, and some include an emergency lancet reuse mechanism that permits emergency reuse of the last lancet And some embodiments include a movable depth-control wall for providing control and adjustment of the lancing penetration depth.
Patent CA-2675871-A1 (CA)
Inventor: ATKINSON FRANCIS STEWART
IPC: E02B3/14
Filed: 2008-03-11
Abstract: An erosion protection device is described which is made of two or more components. Each component has an edge, surfaces on respective sides of the edge and at least one joining portion (a joining portion of a component comprises a recess in the edge and receiving portions on respective sides of the edge). Each recess has a base which is indented relative to the edge, and sidewalls which diverge as they extend from the base out to the edge. The receiving portions diverge relative to each other with the same slope as the sidewalls as they extend from adjacent the base of the recess away from the edge towards the respective surfaces. When joining two components together, a bonding medium is applied to the joining portion on one or both components. The joining portions are then brought together such that the space between the sidewalls and receiving portions of one component and the receiving portions and sidewalls respectively of the other component diminishes thereby squeezing the bonding medium therebetween as the components come together.
Patent CA-2676438-A1 (CA)
Inventor: DATTA AMITAVA
IPC: C25D3/56
Filed: 2006-12-19
Abstract: The invention provides a method and system for electrolytically coating an article. The method includes providing an article to be coated and disposing the article in an electrolytic cell. The cell includes an anode, a cathode in operable communication with the article, and an electrolyte bath. During electrolysis, the electrolyte bath comprises cobalt ions, phosphorous acid, and tribological particles selected from the group consisting of refractory materials, solid lubricants and mixtures thereof dispersed therein. The method further includes applying steady direct electric current through the anode, the electrolyte bath and the cathode to coat the article with cobalt, phosphorous and the tribological particles. An improved composition of matter is also provided that may be used as a coating, or the composition may be electroformed on a mandrel to form an article made from the composition of matter.
Patent CA-2677439-A1 (CA)
Inventor: PHAM VINH PHUC
IPC: G01N23/10
Filed: 2007-09-17
Abstract: A method to perform security screening at an airport on hand-carried baggage.  The method includes requesting passengers with hand carried baggage to remove from the baggage a container that holds a liquid and perform an x-ray inspection on the hand carried baggage and on the container while the container remains outside the baggage. According to the method, the results of the x-ray inspection are used to determine if the baggage contains illegal objects and if the liquid is a security threat.
Patent CA-2681613-A1 (CA)
Title: Signal transfer system
Inventor: BEN-SHALOM AMIR
IPC: H02M1/00
Filed: 2008-03-23
Abstract: A signal transfer system for controlling power transfer across an inductive power coupling (200), said inductive power coupling comprising a primary- inductive coil (220) wired to a power source (240) and a secondary inductive coil (260) wired to an electric load (280); said system comprising: at least one signal generator (120) for generating a control signal (5c); at least one transmitter for transmitting said control signal (5c), and at least one receiver (160) for receiving said control signal (5c). The signal transfer system may be used to regulate the power supplied by the inductive coupling (200) and to detect and align the two coils (220, 260) thereof.
Patent CA-2681842-A1 (CA)
Inventor: BLEISCH PAUL L
IPC: G06F17/00
Filed: 2008-03-20
Abstract: Mechanisms are disclosed that allow for platform abstraction of a computing platform using a programming framework. The programming framework allows application programs to interact with different platforms in an identical manner by abstracting the platform. The application uses identical instructions to the programming framework across different platforms, with the programming framework modifying the instructions to fit platform specific requirements. The programming framework also emulates platform specific expected application behavior on behalf of the application. The programming framework may also provide an additional layer of security for the platform, limiting the access of the application program.
Patent CA-2685465-A1 (CA)
Title: Anti-icos antibodies and their use in treatment of oncology, transplantation and autoimmune disease
Inventor: YAO YIHONG
IPC: A61K39/395
Filed: 2008-05-07
Abstract: The present invention provides anti-human ICOS antibodies with increased effector function. The invention further relates to pharmaceutical compositi ons, immunotherapeutic compositions, and methods using therapeutic antibodie s that bind to the human ICOS antigen and that may mediate ADCC, CDC, and/or antibody-dependent phagocytosis (opsonisation) for the treatment and preven tion of T cell-mediated diseases and disorders, such as, but not limited to, chronic infection, autoimmune disease or disorder, inflammatory disease or disorder, graft-versus-host disease (GVHD), transplant rejection, and T cell proliferative disorder.
Patent CA-2687456-A1 (CA)
Inventor: FREIDIN LEV
IPC: A61N1/372
Filed: 2008-08-12
Abstract: An improved implantable medical device system having dual coils in one of the devices in the system is disclosed. The dual coils are used preferably in an external device such as an external controller or an external charger. The dual coils are wrapped around axes that are preferably orthogonal, although other non- zero angles could be used as well. When used to transmit, the two coils are driven (for example, with FSK-modulated data when the transmitting data) out of phase, preferably at 90 degrees out of phase. This produces a magnetic field which rotates, and which reduces nulls in the coupling between the external device and the receiving coil within the implanted device. Moreover, implementation of the dual coils to transmit requires no change in the receiver circuitry of the implanted device. Should the device with dual coils also receive transmissions from the other device (e.g., the implanted device), the two coils are used in conjunction with optional receiver circuitry which likewise phase shifts the received modulated data signals from each coil and presents their sum to typical demodulation circuitry.
Patent CA-2688996-A1 (CA)
Inventor: CHENG JIE
IPC: C07C217/84
Filed: 2009-12-22
Abstract: Aniline compounds useful as ashless TBN sources for lubricating oil compositions that are compatible with fluoroelastomeric engine seal materials, and lubricating oil compositions containing such aniline compounds.
Patent CA-2689374-A1 (CA)
Inventor: ARAI HITOSHI
IPC: A61P17/06
Filed: 2008-06-02
Abstract: Disclosed is a pyrimidodiazepinone derivative represented by the general formula (I) below, or a pharmaceutically acceptable salt thereof. (I) (In the formula, n represents 1 or 2; Z represents a hydrogen atom or the like; R1 and R2 may be the same or different and represent a hydrogen atom or the like; A represents a bond, a (CH2)m group (wherein m represents an integer of 1-4), an optionally substituted phenylene, an optionally substituted pyridinediyl, or a C=O group; R3 represents a hydrogen atom, an optionally substituted lower alkyl group or the like; and R4 represents a hydrogen atom or the like.)