baber/WOPTO huggingface dataset:
Patent CA-2480273-A1 (CA)
Title: Ph-sensitive polymer
Inventor: SCHULTES KLAUS
IPC: A61K38/00
Filed: 2002-10-22
Abstract: The invention relates to a pH-sensitive polymer which is a (meth)acrylate copolymer composed of 20 to 65 % by weight acrylic and/or methacrylic acid units and 80 to 35 % by weight units of C1- to C18-alkyl esters of (meth)acrylic acid, characterized in that it has a molecular weight in the range from 1 000 to 50 000 g/mol, and brings about at least 60 % haemolysis at pH 5.5, and less than 5 % haemolysis at pH 7.4, in a concentration of 150 µg/ml in a cytotoxicity test with human red blood cells. The invention further relates to the use of the pH-sensitive polymer as carrier for pharmaceutically effective biomolecules or active pharmaceutical ingredients and as ingredient of corresponding dosage forms.
Patent CA-2482064-A1 (CA)
Inventor: KONDO YASUSHI
IPC: A47L9/16
Filed: 2004-09-17
Abstract: The present invention is a floor cleaning apparatus including a housing, an intake opening in the housing, a suction generator carried on the housing and. a dirt collection assembly earned on the housing. The dirt collection assembly is characterized by its unique construction including a partition, a filter assembly, a discharge conduit, a prefilter and a filter.
Patent CA-2482121-A1 (CA)
Inventor: POHL HEIKO
IPC: F16F1/38
Filed: 2004-09-20
Abstract: The invention relates to a bushing, and more particularly a suspension bushing, comprising at least: - a metal or plastic core (2); and - an elastomer body, which is fitted around the core and durably combined with it.      The bushing according to the invention is characterized in that - in the elastomer body or in an additional polymer matrix (18), and more particularly an elastomer matrix, are embedded detectable material particles which act as a rotation angle transmitter (16) which in turn communicates with a rotational angle sensor (17), by which means angular changes within the bushing are detected and are produced as a signal for headlight level adjustment. More particularly, use is made of detectable material particles which enter into a durable bond with the core (2) and in so doing create magnetic fields with alternating poles (N, S) on the core (2), whereby angular changes within the bushing are detected from the number of poles. The material particles utilized are preferably bar magnets or magnetized ferrite particles.
Patent CA-2482173-A1 (CA)
Inventor: REES JON C
IPC: C12Q1/04
Filed: 2003-04-10
Abstract: The invention is directed to a method for detecting low concentrations of bacteria in liquid solution that may or may not be complex liquid solutions.  In one embodiment, immunomagnetic separation (IMS) is used to separate target bacterium that may be in a liquid mixture from other constituents in the mixture. A low concentration of a bacteriophage for the target bacteria is subsequently used to infect target bacterial cells that have been captured using the IMS technique. If at least a certain concentration of target bacterium are present, the bacteriophage will multiply to a point that is detectable. Matrix assisted laser desorption ionization/time-of-flight-mass spectrometry (MALDI/TOF-MS) is then used to produce a mass spectrum that is analyzed to determine if one or more proteins associated with the bacteriophage are present, thereby indirectly indicating that target bacterium were present in the liquid mixture.
Patent CA-2484128-A1 (CA)
Title: Air-fuel ratio control system and method for an internal combustion engine, and engine control unit
Inventor: MAKI HIDETAKA
IPC: F02D45/00
Filed: 2004-10-06
Abstract: An air-fuel ratio control system for an internal combustion engine, which is capable of quickly and properly eliminating variation in air-fuel ratio between a plurality of cylinders. The air-fuel ratio control system 1 controls the amount of fuel to be supplied to first to fourth cylinders #1 to #4, on a cylinder-by-cylinder basis, thereby controlling the air-fuel ratio of a mixture supplied to each of the cylinders. A LAF sensor 14 delivers to an ECU 2 an output KACT indicative of the air-fuel ratio of exhaust gases emitted from the cylinders and merged. A cycle filter 23a and a rotation filter 23b filters the output KACT from the LAF sensor 14 such that components in respective bands of a first frequency fr1 and a second frequency fr2 are allowed to pass therethrough. A final fuel injection amount TOUT i is determined, on a cylinder-by-cylinder basis, according to a first filtered value KACT_Fc or a second filtered value KACT_Fr such that the amplitude of the filtered value KACT_Fc or KACT_Fr converges to a predetermined value.
Patent CA-2485248-A1 (CA)
Title: Method and apparatus for palletizing packages of random size and weight
Inventor: HUANG PAO-TER
IPC: B07C5/04
Filed: 1997-11-21
Abstract: A method and apparatus for palletizing rectangular packages received in random size and weight. A "corner"-based modeling system is used to assist in evaluating possible placements of packages accumulated on a line conveyor, and a placement evaluation process is used to select a "best" package placement based on heuristic analysis. Statistically-based measurement and comparison is used to assist in the evaluation process.
Patent CA-2490901-A1 (CA)
Title: Corrosion resistive silver metal alloys for optical data storage and recordable optical storage media containing same
Inventor: LICHTENBERGER HEINER
IPC: H01M8/04
Filed: 2003-06-24
Abstract: An optical data recording and storage medium includes a reflective layer formed from a silver alloy that contains, in addition to silver, about 0.1 to about 4.0 wt.%, based on the total weight of alloy, of samarium (Sm.)
Patent CA-2491490-A1 (CA)
Title: Method and apparatus for the administration of co
Inventor: KREBS CHRISTIAN
IPC: A61M16/20
Filed: 2003-06-27
Abstract: The present invention relates to a method and apparatus for the administration of carbon monoxide (CO) to a patient. It allows the safe and effective use of carbon monoxide as a medicament.
Patent CA-2491639-A1 (CA)
Title: Expression of the human igf-1 in transgenic plastids
Inventor: DANIELL HENRY
IPC: C12N15/82
Filed: 2003-07-03
Abstract: A plastid transformation vector for a stably transforming a plastid genome, comprising, as operably-linked components, a first flanking sequence, a DNA sequence coding for synthetic insulin-like growth factor-1 (IGF-1s) (seek ID NO. 1) or a substantially homologous DNA sequence of IGF-1s, which is capabl e of expression in the plastid genome, and a second flanking sequence.
Patent CA-2492279-A1 (CA)
Title: Geotextile/polyurethane composites based on blocked isocyanate compositions
Inventor: SEKELIK THOMAS L
IPC: C08G18/80
Filed: 2005-01-12
Abstract: The present invention relates to a geotextile/polyurethane composite prepared from one or more geotextiles and a blocked isocyanate composition and also to a process for preparing such composites. The inventive geotextile/polyurethane composites may find use as liners for canals and ditches for irrigation and wastewater, roof membranes, secondary containment, etc.
Patent CA-2492772-A1 (CA)
Title: Activated checkpoint therapy and methods of use thereof
Inventor: LI CHIANG J
IPC: C12Q1/68
Filed: 2003-07-17
Abstract: Disclosed herein are novel methods and compositions for Activated Checkpoint TherapyTM. Also disclosed are methods of treating cancer and apoptosis- associated disorders using cell cycle checkpoint activation modulators. The invention further discloses methods for screening for cell cycle checkpoint activation modulators and the cell cycle checkpoint activation modulators identified by those screening methods.
Patent CA-2492933-A1 (CA)
Title: Method and device for screening molecules in cells
Inventor: FUCHS ALEXANDRA
IPC: C12N15/09
Filed: 2003-07-21
Abstract: The invention concerns a method for reacting a reagent R with a cell C, which consists in: setting the cell C on a support S comprising a substantially planar surface, in the form of an aqueous drop on said surface; covering the planar surface of the support S whereon the aqueous drop has been set containing the cell C with a separation film F, allowing through gases and preventing the aqueous drops set on the support S from evaporating, F being non-miscible with the reagent R; triggering the reaction between the reagent R and the cell C by introducing the reagent R in the aqueous drop containing the cell C. The invention also concerns a device for implementing said procedure and its applications.
Patent CA-2493648-A1 (CA)
Inventor: DUNN THOMAS MICHAEL
IPC: H05B7/148
Filed: 2003-07-22
Abstract: L'invention concerne un procédé permettant de produire de l'acier dans un four (10) à arc électrique. Les étapes de ce procédé consistent à mesurer le courant électrique dans au moins deux phases de courant alimentant les électrodes placées dans le four au cours d'une campagne, à établir une valeur de consigne pour le courant, et un intervalle de temps d'alimentation, et à effectuer une commutation entre modes permettant l'apport d'énergie exothermique dans l'acier en fusion lorsque les phases mesurées présentent des niveaux de courant inférieurs à la valeur de consigne pendant l'intervalle de temps d'alimentation.
Patent CA-2495774-A1 (CA)
Title: Phosphore en couche mince traite a basse temperature pour affichages electroluminescents
Inventor: WESTCOTT MICHAEL R
IPC: H05B33/12
Filed: 2003-09-10
Abstract: L'invention concerne une structure phosphorescente en couche mince, qui peut être traitée sur un support comportant du verre ou de la céramique vitrifiée couverte de barrettes d'électrodes en couche mince à faibles températures. Cette structure phosphorescente perfectionnée, destinée à un affichage électroluminescent diélectrique en couche épaisse, comprend un stratifié phosphorescent composé d'une couche mince phosphorescente émettant de la lumière bleue et d'une couche mince contenant du fluorure, ces deux couches étant directement adjacentes et la couche contenant du fluorure se trouvant en haut et/ou en bas de la couche mince phosphorescente.
Patent CA-2501541-A1 (CA)
Inventor: JONES LYN HOWARD
IPC: C07D231/18
Filed: 2003-09-24
Abstract: La présente invention concerne des dérivés de pyrazole représentés par la formule (I) ou des sels, des solvates ou de dérivés de ces composés répondant aux normes pharmaceutiques. Dans cette formule R?1¿ à R?4¿ sont tels que définis dans les descriptions. Cette invention concerne aussi des processus de préparation de ces composés, des intermédiaires utilisés dans la préparation de compositions contenant ces composés et les utilisations de ces dérivés. Les composés de cette invention se lient à l'enzyme transcriptase inverse et sont des modulateurs et, plus particulièrement des inhibiteurs de celle-ci. En tant que tels, ces composés conviennent pour le traitement de diverses pathologies dans lesquelles l'inhibition de la transcriptase inverse est impliquée. Des pathologies d'intérêt incluent les pathologies induites par le virus de l'immunodéficence humaine VIH et par les virus génétiquement liés, telles que de syndrome d'immunodéficience acquis (SIDA).
Patent CA-2502128-A1 (CA)
Inventor: PARK EDWARD H
IPC: C09J127/20
Filed: 2005-03-23
Abstract: Composites of polytetrafluoroethylene and a structural material (polymer, metal, ceramic, leather, or wood) are bonded with a cured admixture of tetrafluoroethylene-hexafluoropropylene-vinylidene fluoride terpolymer, polyethylene-oxide-modified silicone polymer coupling agent, and oxygen-radical-containing copolymer (epoxy polymer, phenoxy polymer, or hydroxylated diamine-diepoxide derivative copolymer). The bonded surface of the polytetrafluoroethylene portion of the composite is etched (chemical etching, electron-beam etching, laser etching, or plasma etching) prior to application of uncured admixture. The composites are useful in making items such as seals, gaskets, chemically-resistant hoses, o-rings, and pump diaphragms.
Patent CA-2504149-A1 (CA)
Inventor: HOFMANN GEORGE HENRY
IPC: C08L29/14
Filed: 2003-11-26
Abstract: L'invention concerne une composition élastomère thermoplastique qui renferme du polyvinylbutyral élastomère réticulé et un polymère thermoplastique, et un procédé d'élaboration correspondant.
Patent CA-2506195-A1 (CA)
Title: Metabolically engineered micro-organisms having reduced production of undesired metabolic products
Inventor: BRO CHRISTOFFER
IPC: C12P37/00
Filed: 2003-11-25
Abstract: A metabolically engineered micro-organism has an operative first metabolic pathway in which a first metabolite is transformed into a second metabolite in a reaction in which NAD is a cofactor for a first enzyme, suitably a phosphorylating dehydrogenase, said reaction step producing NADH. Said second metabolite is transformed into at least one further metabolite in a reaction catalysed by a second enzyme, suitably a kinase. The organism has an operative second metabolic pathway characterised by an enzyme activity in excess of a native level in respect of a third enzyme, suitably a non-phosphorylating dehydrogenase, e.g. GAPN, catalysing a non-reversible reaction in which NADP  is a cofactor and NADPH is a product. Said first metabolite is transformed into a said further metabolite without the involvement of said second enzyme.
Patent CA-2506342-A1 (CA)
Title: Yieldable cone bolt for use in small diameter bolt holes and method of installing the same
Inventor: CHAMPAIGNE DENIS
IPC: E21D21/00
Filed: 2005-05-04
Abstract: A mine roof support system for use with bore holes having diameters at between about 1 to 1 3/8 inches includes an elongated metal anchor rod or cone bolt, a threaded fastener and a grout or resin composition used to secure at least part of the anchor rod in a pre-drilled bolt hole. The anchor rod includes an externally threaded outer proximal end portion which is provided with one or more enlarged frustoconical shaped projections. The innermost distal end of the anchor rod further includes at least one axially extending projection which, in a simplified construction, is formed as an elongated tongue shaped member which presents generally planar major side surfaces. The frustoconical shaped projections preferably taper in the direction away from the outer proximal end portion of the anchor rod at an angle of about 3.5°, inclined relative to the longitudinal axis of the anchor rod. The tongue shaped member defines at least one, and more preferably two generally opposing major side surfaces which extend in the axial direction between about 4.5 and 7 cm.
Patent CA-2507148-A1 (CA)
Title: Portable bench
Inventor: TENNIAN THOMAS H
IPC: A47C4/00
Filed: 2005-05-12
Abstract: A portable seating device is provided in the form of at least two horizontal planks having respective coupling ends along which such members may be joined. The underside surfaces of these planks are provided with vertical support containment means. Such vertical support containment means serve to contain and localize the upper end of a central vertical support placed against the underside surfaces of the two horizontal seating members, overlapping their connected coupling ends. A preferred central vertical support is a tapered pail or bucket which may or may not have its carrying handle removed. Additional vertical supports may be provided to underlie further portions of the underside surfaces of the horizontal planks, deployed symmetrically on either side of the central vertical support and similarly localized against the underside surfaces.
Patent CA-2507232-A1 (CA)
Inventor: FICHT REINHOLD
IPC: B63B7/08
Filed: 2003-05-06
Abstract: The invention relates to a motor-driven device comprising a keel-less boat body consisting of at least two parallel inflated tubes (1, 2), placed at a distance from one another and a substantially rigid or fixed base (6) located between said tubes. An air propeller propulsion device (25) is mounted on the base in a raised manner, together with steering devices (27) and control units (31, 32) for the propulsion device.
Patent CA-2507725-A1 (CA)
Inventor: SAITO KAZUNORI
IPC: G01N33/92
Filed: 2003-11-26
Abstract: A method of measuring a lipid in a specific lipoprotein characterized by using a polycyclic polyoxyalkylene derivative at least in the step of determining the specificity of the measurement of the target lipid.
Patent CA-2508307-A1 (CA)
Inventor: GHOSH BALARAM
IPC: A61P11/06
Filed: 2002-12-02
Abstract: L'invention porte: sur une méthode de prévention et/ou traitement de l'asthme chez un patient consistant à lui administrer une dose pharmacocompatible efficace de bromure de parabromophénacyle (PBPB), et sur une méthode de modulation du niveau de biomolécules donnant le même résultat.
Patent CA-2508333-A1 (CA)
Title: Single pot conversion of artemisinin to artesunic acid
Inventor: KAHOL ATUL PRAKASH
IPC: C07D493/18
Filed: 2002-12-02
Abstract: The present invention provides a single pot process for the preparation of artesunic acid from artemisinin involving reduction followed by esterification of the reduced product at room temperature.
Patent CA-2513005-A1 (CA)
Inventor: FOWLER JOHN
IPC: A41D13/12
Filed: 2003-01-31
Abstract: The disclosure relates to the field of medical equipment and relates particularly to clothing for hospital patients who may undergo physical examination or surgical procedures. The present invention seeks to provide medical clothing which allows easy access to the patient's body for the purpose of examination, treatment or surgery but which also provides coverage akin to normal clothing so that the patient does not feel inhibited or exposed. According to one aspect of the present invention there is provided medical clothing for a patient, comprising a gown formed with two arm apertures and an open front portion, which is arranged to close around the patient's torso by overlapping of respective sides thereof, and means of fastening the respective sides in an overlapped posititon. Preferably, each arm aperture is provided with releasable fastening means for reducing or enlarging the extent of the arm aperture. Beneficially, the arm aperture fastening means may be located in an under-arm portion of the arm aperture.  According to another aspect of the invention there is provided medical clothing for the lower body of a patient, which clothing is configured as a pair of trousers having a waist portion and two leg portions, which trousers are provided with a releasably fastenable access cut which extends from the waist portion to an end cuff of one leg portion, thereby permitting access to the covered portion of the patient's groin and corresponding leg by unfastening of the cut.
Patent CA-2514911-A1 (CA)
Title: Hand held appliances
Inventor: HAWES CHRISTOPHER MARTIN
IPC: A61C17/34
Filed: 2004-02-19
Abstract: A hand held electrical appliance having a handle and a head part to be brought into contact with the body of the user, such as a toothbrush with a brush head, and especially a safety razor with a head part in the form of a blade unit (2), wherein an electrically operable vibration generating device, for example an electric motor (24) and eccentric weight (26), and a control device (16) for controlling operation of the vibration generating device are provided. The control device is proximity or touch sensitive and includes a sensor element, such as an electrode formed by a blade (4) of the blade unit (2), so that the vibration generating device is actuated in response to a person using the appliance moving the blade unit (or other head part) into close proximity to or into contact with the body area to be treated. Due to the vibration generating device being operated only when the head part is applied or about to be applied to the body, the discomfort of holding a vibrating appliance in the hand, as perceived by a user, is greatly diminished.
Patent CA-2517365-A1 (CA)
Title: Riser pipe support system and method
Inventor: WYBRO PIETER G
IPC: B63B21/50
Filed: 2004-02-27
Abstract: A system and method for mating risers or umbilicals (14) extending vertically or near vertically from the ocean floor to a floating offshore system (10).  The risers or umbilicals (14) are suspended vertically above the vessel's keel and are supported laterally near the platform's keel by keel guides or riser receptacles (7).
Patent CA-2518184-A1 (CA)
Title: Reinforced soil structure and method for constructing it
Inventor: MORIZOT JEAN-CLAUDE
IPC: E02D29/02
Filed: 2004-10-11
Abstract: The reinforced soil structure comprises a fill, a facing (3) placed along a front face of the structure, main reinforcement strips (2) disconnected from the facing and extending in a reinforced zone of the fill situated behind the front face, and secondary elements (6) connected to the facing and extending in a zone of the fill which exhibits, with the reinforced zone, a common part (z~) where loads are transmitted between the main reinforcement strips and the secondary elements by the material of the fill.
Patent CA-2519354-A1 (CA)
Title: A wellbore apparatus and method for completion, production and injection
Inventor: DALE BRUCE A
IPC: E21B43/04
Filed: 2004-01-20
Abstract: A wellbore apparatus and method suitable for either wellbore completions and production. The completion and production apparatus comprises at least one primary flow joint (13), the primary flow joint comprising at least one three-dimensional surface defining a body capable of fluid flow with at least one permeable surface, and at least one secondary flow joint (15), the secondary flow joint comprising at least one three-dimensional surface defining a body capable of fluid flow with at least one permeable surface. The method comprises providing a completion and production apparatus comprising at least one primary flow joint and one secondary flow joint wherein multiple fluid flow paths can be provided. The production completion apparatus may be installed into the wellbore (10) to provide at least two flowpaths in the wellbore during well completion, injection and production.
Patent CA-2520636-A1 (CA)
Title: Variant humicola grisea cbh1.1
Inventor: LARENAS EDMUND A
IPC: C12N15/74
Filed: 2004-03-26
Abstract: ABSTRACT OF THE DISCLOSURE Disclosed are variants of Humicola grisea Cel7A  (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted.
Patent CA-2521965-A1 (CA)
Title: Somatostatin-dopamine chimeric analogs
Inventor: DONG ZHENG XIN
IPC: A61K38/00
Filed: 2004-04-08
Abstract: The invention features somatostatin-dopamine chimeric analogs and methods relating to their therapeutic use for the treatment of neoplasia, acromegaly, and other conditions.
Patent CA-2523187-A1 (CA)
Title: Drape product for surgical interventions
Inventor: KARLSSON FREDRIK
IPC: A61B19/08
Filed: 2004-06-02
Abstract: The present invention relates to a drape product for surgical interventions, comprising an opening (0) intended to be arranged around an operating site o n a patient, which drape product, during use, forms a barrier between the operating site and that part of a patient's body lying outside the operating site. The drape product comprises at least one member (10, 11) for receiving and/or securing sutures or the like, through which member a suture or the li ke can be passed without damaging or destroying the barrier between the operati ng site (0) and that part of a patient's body lying outside the operating site.
Patent CA-2523502-A1 (CA)
Inventor: FLETCHER IAN MARK
IPC: B01J19/02
Filed: 2004-04-26
Abstract: The invention relates to the use of a coated manufacturing vessel in pharmaceutical production. A polymer coating (ECTFE, PVDF, PFA) avoids the adhesion or sticking of compounds within the vessel.