baber/WOPTO huggingface dataset:
Patent EP-0934304-B1 (EP)
Inventor: DAVIS PETER DAVID
IPC: A61P19/02
Filed: 1997-10-27
Granted: 2003-02-26
Abstract: Compounds of general formula (1)are described wherein:Ar is an optionally substituted aromatic group;R2 is a hydrogen or halogen atom or a group -X1-R2a where X1 is a direct bond or a linker atom or group, and R2a is an optionally substituted straight or branched chain alkyl, alkenyl or alkynyl group;R3 is an optionally substituted heterocycloalkyl group;and the salts, solvates, hydrates and N-oxides thereof.The compounds are selective protein tyrosine kinase inhibitors, particularly the kinases ZAP-70 and syk and are of use in the prophylaxis and treatment of immune or allergic diseases and diseases involving inappropriate platelet activation.
Patent EP-0906108-B1 (EP)
Inventor: LYNCH JOSEPH J JR
IPC: A61K31/505
Filed: 1997-03-19
Granted: 2005-06-15
Abstract: A method for preventing and/or treating heart failure and ventricular dysfunction in a warm blooded animal comprising administering to the warm blooded animal a therapeutically effective amount of an endothelin antagonist of the formula: as defined herein.
Patent EP-0904367-B1 (EP)
Title: Scf analog compositions and methods
Inventor: LU HSIENG SEN
IPC: A61K38/00
Filed: 1997-04-03
Granted: 2007-05-30
Abstract: The present invention relates to stem cell factor analog polypeptide compositions, and vectors, host cells, and processes for recombinant DNA production of the present stem cell factor analogs. Pharmaceutical compositions and methods of use are also disclosed.
Patent EP-0892826-B1 (EP)
Inventor: LUND EARL AUGUST EUGENE
IPC: C09K3/00
Filed: 1997-04-02
Granted: 2002-03-13
Abstract: Azeotrope-like compositions of 1,1,1,3,3-pentafluoropropane and at least one hydrocarbon selected from the group n-pentane, iso-pentane, cyclopentane, n-hexane and iso-hexane are provided. The compositions of the invention are useful in the preparation of polyurethane and polyisocyanurate foams.
Patent EP-0914091-B1 (EP)
Inventor: JAMESON WARWICK MURROW
IPC: A61P31/18
Filed: 1997-05-14
Granted: 2003-09-10
Abstract: The present invention provides ethene containing solutions and the use thereof in methods of therapy and prophylaxis. Specifically provided are storage stable solutions comprising ethene solubilized in a suitable liquid. Methods of therapy and prophylaxis contemplated include direct and indirect action against disease and microorganisms, as well as methods for improving metabolic function and priming or causing a host to mount a protective response against disease or microorganisms.
Patent EP-0898537-B1 (EP)
Inventor: TRASSINELLI DUCCIO
IPC: B62B5/00
Filed: 1997-05-14
Granted: 2000-03-01
Abstract: A multi-purpose support structure with an extendable handle and retractable wheels, comprises in combination: a support frame (2) with a pair of longitudinal uprights (4), each comprising first and second guide channels (6, 8) extending parallel to each other side by side; a handle element (14), with two parallel sides (12) slidable within said first guide channels (6) and with a transverse connecting side (16) forming a gripping element; a pair of rods (18) provided lowerly with wheels (20) and slidable within said second guide channels (8), and means (22, 28) for simultaneously and opposingly moving said parallel sides (12) of said handle element (14) and said rods (18) along their respective guide channels (6, 8).
Patent EP-0907754-B1 (EP)
Inventor: COMPAGNI NUNZIO
IPC: B65H29/38
Filed: 1997-05-23
Granted: 2003-08-06
Abstract: Cet appareil, destiné à la manutention d'articles sensiblement plats et souples (2), notamment des peaux, comprend des moyens de transfert suspendus (3; 3a) servant à supporter et transférer les articles (2), des moyens de transport (5) de ces articles (2), coopérant avec des moyens de déplacement (8, 11; 73, 11a), lesquels sont mobiles verticalement et déplacent les articles (2) entre les moyens de transfert (3; 3a) et les moyens de transport (5). Le procédé de l'invention consiste à enlever ces articles (2) des moyens de transfert suspendus (3; 3a) ou à les y apporter, aux fins de support et de transfert de ceux-ci (2), cet enlèvement et/ou cet apport s'effectuant grâce auxdits moyens de déplacement (8, 11; 73, 11a), lesquels sont mobiles verticalement entre les moyens de transfert (3; 3a) et ceux de transport s'étendant vers le bas (5), et vice versa.
Patent EP-0909437-B1 (EP)
Inventor: GADONNIEX DENNIS MICHAEL
IPC: G08B13/22
Filed: 1997-06-05
Granted: 2003-03-19
Abstract: Un élément magnétique semi-dur est formé en cristallisant au moins partiellement un matériau métalloïde-fer doux amorphe (20). Le processus de chauffage (26, 30, 34, 38, 40) destiné à terminer la cristallisation comprend un étage d'oxydation contrôlée (26, 30) qui améliore le niveau du flux d'induction rémanente qui est obtenu lorsque l'élément magnétique traité se trouve dans un état entièrement magnétisé.
Patent EP-0923501-B1 (EP)
Inventor: SEMMLER GEORG
IPC: B65H35/00
Filed: 1997-08-13
Granted: 2001-12-19
Abstract: The invention relates to a handheld implement for transferring a film (25) from a backing strip (7) wound on a supply reel (5) onto a substrate, the said implement having a housing (2), a pressure-exerting part (16) projecting therefrom, and two bearing and/or carrier devices for the supply reel (5) and a take-up reel (6) for the backing strip (7) guided around the pressure-exerting part (16), the housing being able to be opened for the purposes of replacing the reels (5, 6). In order to be able to load such a handheld implement simply and quickly without the costs and material expenditure involved in a replaceable cassette, a loading aid (30) provided for loading the opened housing (2) with the reels (5, 6) is proposed in a mutual arrangement of these reels (5, 6) that is substantially identical to that of the bearing and/or carrier devices, the loading aid having at least one guide element (34) associated with the guide surface (16b, 18) of the pressure-exerting part (16), which element is designed to ensure that the backing strip (7) extending between the two reels (5, 6) rests against the latter in such a way that when the loading aid (30) is in place it at least partially surrounds or envelopes the pressure-exerting part (16).
Patent EP-0861007-B1 (EP)
Inventor: VANLANDEGHEM MARC
IPC: H04M3/54
Filed: 1998-02-19
Granted: 2004-06-16
Abstract: The communication system provides connections between internal subscribers and between internal and external subscribers via the public network, under control of a central control with a system memory (SPE) and a system processor (CPU). The system memory can be used for holding frequently called external numbers for each internal subscriber, for implementation of a call connection procedure in which the external number is connected to the identified internal subscriber provided from the stored list in priority to the internal subscriber selected by the external subscriber.
Patent EP-0944151-B1 (EP)
Inventor: ROZ THIERRY
IPC: H02H9/04
Filed: 1998-03-18
Granted: 2003-12-03
Abstract: The protection structure (20) is connected to an external terminal (A) of a transponder (16) to be protected, connected to a transmitting/receiving antenna. The structure is formed from three diffusion zones (34,35,36) which are of a P<+> conductivity type and which are formed in an encasing zone (32) of an N<-> conductivity type formed in a semiconductor substrate (30) having a P<-> type of conductivity. Two (34,36) of the three zones are connected to a reference electrical potential (Vss), and the other zone (35) is connected to the external terminal.
Patent EP-0905425-B1 (EP)
Inventor: HALPAUS WOLFGANG
IPC: F16L3/24
Filed: 1998-09-04
Granted: 2008-04-02
Abstract: The fixing element has an internally threaded part (2) with collar (21) over which a tab (1), disc (3) and pressure disc (4) are pushed. The disc is made of foam rubber and is coated on its top and bottom sides (31,32) with a fixed adhesive layer whose outer diameter is slightly larger than the width of the slit (61) in the hollow profiled support (6). - The pressure disc (4) has edges whose outer spacings are less than the slit width. The tab is connected quasi rigid to the pressure disc by the disc (3) and the parts (1,3,4) are pushed onto the outer thread of the component part (2).
Patent EP-0919601-B1 (EP)
Inventor: REHFUSS JOHN
IPC: C08G59/14
Filed: 1998-12-01
Granted: 2006-03-01
Abstract: There is described a curable coating composition having at least one effect pigment which, upon cure, exhibits substantially improved orientation of the effect pigment and a corresponding improvement in appearance. The composition comprises:   (A) a carbamate-functional component having a hydrophobicity equivalent to or greater than that of a carbamate-functional compound (A') which is the reaction product of:   (1) a compound comprising a plurality of hydroxyl groups, at least one of which is the result of a ring-opening reaction between an epoxy group and an organic acid group, and   (2) cyanic acid or a compound comprising a carbamate group, and   (B) a component comprising a plurality of groups that are reactive with the carbamate functional groups on component (A), and   (C) at least one effect pigment, the curable coating composition when cured having a substantially improved effect pigment orientation. Preferably, the composition further comprises particular rheology control agents.
Patent EP-0939251-B1 (EP)
Inventor: KATAUMI YOSHIMASA
IPC: F16H59/10
Filed: 1998-12-14
Granted: 2003-05-02
Abstract: A shift-lever device includes a position plate (17) integrated with a base plate (14) and formed with a detent groove (18), a shift lever (1) supported to the base plate to be swingable along the position plate and including a base (7) arranged adjacent to the position plate, and a compression rod (2) arranged through the shift lever to axially be movable by operation of a knob button (11). A detent protrusion (3) is arranged with the compression rod at a lower end to be engageable with the detent groove. A guide (7a) integrated with the base of the shift lever holds part of the detent protrusion longitudinally with respect to a vehicle body. <IMAGE>
Patent EP-0898084-B1 (EP)
Inventor: IGA MAKOTO
IPC: F15B21/0423
Filed: 1998-01-27
Granted: 2005-11-16
Abstract: L'invention concerne un circuit pilote de régulation de pression hydraulique présentant une pompe pilote qui délivre un fluide pilote, ainsi qu'une pluralité de vannes pilotes qui régulent une pluralité de vannes de sélection de pression hydraulique en régulant l'alimentation en fluide pilote. Dans ce circuit pilote, la chaleur du fluide de travail provoquée par la retenue du fluide pilote est réduite, et, même si une pluralité de vannes pilotes fonctionnent simultanément, le fluide pilote peut être acheminé en quantité suffisante aux vannes pilotes et son aptitude fonctionnelle n'est pas affectée. Une pompe à débit variable est employée en tant que pompe pilote. Les états fonctionnels des vannes pilotes hydrauliques sont détectés par des moyens de détection et la quantité de fluide pilote délivré, nécessaire pour faire fonctionner les vannes de sélection de pression hydraulique, est calculée par un contrôleur et seule la quantité requise de fluide de travail est délivrée à la pompe pilote.
Patent EP-0897738-B1 (EP)
Inventor: SAKATA SOICHIRO
IPC: B01J20/28
Filed: 1998-01-30
Granted: 2006-04-05
Abstract: An air cleaning apparatus such as a clean room or the like having an air circulation mechanism which circulates the humidity controlled air through a predetermined air circulation path, wherein the air circulation path is provided with a filter which has a hydrophobic zeolite layer formed on its base filter media surface and another filter which is disposed downstream from the filter having a hydrophobic zeolite layer and is used for removing particulate impurities contained in the circulating air. According to this air cleaning apparatus, gaseous organic impurities and particulate impurities contained in the air circulating in the air cleaning apparatus can be removed without lowering the humidity of the circulating air. Furthermore, since this air cleaning apparatus includes no activated charcoal which is inflammable, the apparatus is excellent from the standpoint of disaster prevention. Accordingly, the filters according to the invention and particle filters can be installed with safety in the ceiling portion of the air cleaning apparatus. <IMAGE>
Patent EP-0971927-B1 (EP)
Inventor: HILER GEORGE DOUGLAS II
IPC: C07D487/08
Filed: 1998-03-06
Granted: 2005-06-15
Abstract: Improved synthesis of a macropolycycle, more particularly, of a cross-bridged tetraazamacrocycle.
Patent EP-0968189-B1 (EP)
Inventor: SHARMA PADAM N
IPC: C07D213/803
Filed: 1998-02-18
Granted: 2001-11-07
Abstract: The present invention relates to an improved process for the preparation of nicotinic acids represented by the following structural formula (I):    <IMAGE>  I  which are prepared by reacting a nicotinic amide compound having the formula:   <IMAGE>   under acidic conditions with a nitrite salt. In the process of the invention have the groups R1, R2, and R3, in the compounds are independently selected from the group consisting of hydrogen, and halogen atoms and R4 is selected from the group consisting of hydrogen, lower alkyl and aryl. The process provides the nicotinic acid compounds in improved yields.
Patent EP-0964864-B1 (EP)
Inventor: BOSCHELLI DIANE HARRIS
IPC: C07D405/12
Filed: 1998-01-26
Granted: 2008-04-09
Abstract: This invention provides pyridopyrimidines and 4-aminopyrimidines that are useful for treating cell proliferatives disorders, such as cancer and restenosis. We have now discovered a group of 7,8-dihydro-2-(amino and thio)pyrido[2,3-d]pyrimidines and 2,4-diaminopyrimidines that are potent inhibitors of cyclin-dependent kinases (cdks) and growth factor-mediated kinases. The compounds are readily synthesized and can be administered by a variety of routes, including orally, and have sufficient bioavailability. This invention provides compounds of Formula (I) and Formula (II) where W is NH, S, SO, or SO2, R<1> includes phenyl and substituted phenyl, R<2> includes alkyl and cycloalkyl, R<3> includes alkyl and hydrogen, R<8> and R<9> include hydrogen and alkyl, and Z is carboxy. This invention also provides pharmaceutical formulations comprising a compound of Formula (I or II) together with a pharmaceutically acceptable carrier, diluent, or excipient therefor.
Patent EP-0975557-B1 (EP)
Inventor: RONIN VLADIMIR
IPC: C04B28/02
Filed: 1998-03-23
Granted: 2001-07-25
Abstract: A method of treating cement clinker by grinding the clinker in a tubular mill while charging water, gypsum, and, optionally, also a water-reduction agent to the mill at the same time. The water has a pH of from about 9 to about 13. A microfill agent and/or a water-reduction agent is mixed with said the high pH-value water to form a slurry, which is added to the clinker during the grinding process together with microfill agent and/or water-reduction agent in a dry state. The high pH value of the water can be obtained by electrolysis.
Patent EP-1075370-B1 (EP)
Inventor: CHANDRAKER VINAY KUMAR
IPC: B29C48/27
Filed: 1998-05-07
Granted: 2005-07-27
Abstract: This invention pertains to cleaning compositions and methods for cleaning a first polymer composition from polymer processing apparatus. The cleaning compositions generally comprise a second polymer composition and at least one metal salt composition wherein the respective metal is selected from alkaline earth and transition metals. The second polymer composition has an affinity, for the first polymer, of "Ad" between 50 and about 1500, where "Ad" is adhesive strength, grams/15mm width, between the first and second polymer compositions in a multiple layer cast coextruded film. The cleaning composition comprises about .001 to about 10 weight percent metal salt composition based on total weight of the cleanin composition. A 50/50 weight percent mixture of the second polymer composition, and a third polymer composition which can be processed in polymer processing apparatus suitable for processing the first polymer composition, preferably has a melt index ratio MI-mix60/MI-mix6 of 0.3/1 to 5/1.
Patent EP-0981542-B1 (EP)
Inventor: LERCHEN HANS-GEORG
IPC: A61P35/00
Filed: 1998-05-04
Granted: 2004-08-04
Abstract: The present invention relates to glycoconjugates of 20(S)-camptothecin, in which a 3-O-methylated beta-L-fucose unit is linked to the 20-hydroxyl group of a camptothecin derivative via a thiourea-modified peptide spacer. The invention furthermore relates to processes for the preparation of the compounds according to the invention and to their use as medicaments, in particular in connection with oncoses.
Patent EP-1000134-B1 (EP)
Inventor: MERTENS BAUDOUIN
IPC: C11D1/83
Filed: 1998-07-29
Granted: 2003-10-15
Abstract: An improvement is described in all purpose liquid cleaning composition which is especially effective in the removal of oily and greasy soil and also exhibiting improved foam collapse properties, contains an anionic detergent, an ethoxylated nonionic surfactant, an ethoxylated/butoxylated nonionic surfactant, optionally, a partially esterfied ethoxylated polyhydric type alcohol, a hydrocarbon ingredient, and water.
Patent EP-0996749-B1 (EP)
Inventor: DENYS MARK BERNARD
IPC: C21B13/00
Filed: 1998-07-03
Granted: 2001-11-28
Abstract: Method for controlling a smelting reduction process, in particular a cyclone converter furnace process for producing pig iron, characterized in that one:measures the carbon fraction C in the off-gas in the form of CO and Co2O;measures the hydrogen fraction H2 in the off-gas in the form of H2 and H2O;determines the C/H2 ratio in the off-gas;compares the C/H2 ratio thus determined in the off-gas against the C/H2 ratio prevailing for the coal being supplied, andadjusts the coal supply based on the difference found in the C/H2 ratios in the off-gas and the coal being supplied.
Patent EP-1026758-B1 (EP)
Inventor: HASUNUMA TAKASHI
IPC: H01M50/574
Filed: 1998-09-17
Granted: 2002-01-23
Abstract: A battery pack and a PTC device are provided that can be used safely under large current loads by increasing the area of the incorporated PTC layer so as to decrease its internal resistance. The battery pack has a plurality of unit cells (1) placed side by side in parallel and the PTC device P to protect the unit cells (1) from overcurrents. The PTC device P has a first electrode (3) and a second electrode (4) connected to the both surfaces of the PTC layer (2). The PTC layer is formed to an outer shape that covers almost the entire of the end surfaces of the two unit cells (1) to which the first electrode (4) and the second electrode (4) are connected, and has through holes (2B) positioned against the end electrodes (1A) of the unit cells (1). The first electrode (3) and the second electrode (4) connected to the both surfaces of the PTC layer (2) are formed to an outer shape almost the same as the outer shape of the PTC layer (2); and the first electrode (3) and the second electrode (4) are connected to the end electrodes (1A) of the unit cells (1) at points where the through holes (2B) of the PTC layer (2) are located. <IMAGE>
Patent EP-1024764-B1 (EP)
Inventor: ORY FRANCOIS REGIS
IPC: A61L27/00
Filed: 1998-10-21
Granted: 2001-08-22
Abstract: A prosthetic implant for obturating an anatomical duct, cavity or orifice, has a porous textile element obtained from a prosthetic fabric, having a flat and nongathered up configuration in the shape of a patch with a continuous outer edge or periphery. The implant has at least two radial elements extending and distributed around a central zone free from any radial element. The radial element centripetally stresses the remaining periphery of the textile element. A peripheral zone having radial elements is comprised of at least two superimposed panels of prosthetic fabric. The radial elements are in the shape of textile strips and consist of a multiplicity of stitches linking the two panels with at least one thread.
Patent EP-1019430-B1 (EP)
Inventor: KLEIBER JOERG
IPC: C12Q1/6806
Filed: 1998-09-29
Granted: 2007-07-11
Abstract: Isolation of an analyte (I) from a biological sample comprising: (i) decomposing the sample in a reaction vessel; (ii) adding a solid adsorption matrix (A); (iii) incubating so that (I) binds to (A); (iv) removing non-bound components from the vessel; (v) incubating so that (I) is eluted from (A); and (vi) separating the eluate from (A). Independent claims are also included for the following: (1) reagent kits for the process comprising protease; buffers for sample decomposition, washing and elution, and a suspension of magnetic glass particles; (2) apparatus for the process; and (3) magnetic glass particles (B) comprising a magnetic core and glass shell containing silica, boron oxide and alkali metal oxide, optionally also alumina and alkaline earth metal oxide.
Patent EP-1025423-B1 (EP)
Title: Method and device for determining a route from the originating point to the terminating point
Inventor: STEINER DONALD
IPC: G01C21/20
Filed: 1998-09-30
Granted: 2001-11-21
Abstract: In an iterative method and system, a route is determined from a starting point to a destination point. Sub-modules are supplied with digital messages that respectively contain at least one sub-starting point and one sub-destination point that are contained in a sub-route map that is allocated to the respective sub-module that receives the respective message. Each sub-module determines a sub-route between the respective sub-starting point and the respective sub-destination point. The route is formed from the sub-route.
Patent EP-1034251-B1 (EP)
Inventor: TAM YUN K
IPC: C12M3/06
Filed: 1998-11-30
Granted: 2004-01-21
Abstract: The invention relates to a system and method for assessing simulated biological dissolution of a pharmaceutical formulation and absorption of a pharmaceutically active compound therefrom. The system comprises a dissolution chamber and a cell culture chamber. Within the dissolution chamber, the dissolution profile of the pharmaceutical formulation (or drug) is determined. Within the cell culture chamber, the pharmaceutically active compound may be absorbed and transported by a cell monolayer. The cell culture chamber includes a tubular filter which is permeable to medium and capable of supporting the cell monolayer on its interior surface. Insertion of the filter into the cell culture chamber housing forms an apical chamber interior of the filter, and a basal chamber between the filter and the wall of the housing. The filter rotates about an axis within the housing substantially parallel to the direction of media flow through the cell culture chamber. The medium flowing from the dissolution chamber contains the pharmaceutical formulation and is provided to the apical chamber. The rate of appearance of the pharmaceutically active compound in the medium outflowing from the basal chamber may be analysed to determine absorption of the pharmaceutically active compound.
Patent EP-1076879-B1 (EP)
Inventor: DE JAEGER GOTFREDSEN BJARKE
IPC: G06K7/00
Filed: 1998-12-07
Granted: 2002-04-17
Abstract: A mouse pad comprises at least one card read/write device. The mouse pad is adapted to be coupled to a computer through a wired or wire-less connection so that the connection creates a link between the computer and the card read/write device. <IMAGE>
Patent EP-1013233-B1 (EP)
Inventor: JERGER THOMAS DR
IPC: A61B17/92
Filed: 1999-12-21
Granted: 2001-10-24
Abstract: The appliance (1) for driving an elongated wire pin into bone consists of a forward thrust appliance (8) driven by a repetition of hammer (9) blows. The forward thrust appliance is in the form of a transmission piece (11). The wire pin moves longitudinally through a guide sleeve (5) in a head part (3). The hammer part is in the form of a drive piston periodically driven in a drive pipe (10). the end section of the drive part facing the head part has an intermediate sleeve (19).