baber/WOPTO huggingface dataset:
Patent CA-2510891-A1 (CA)
Title: Rapid direct sequence analysis of multi-exon genes
Inventor: DUNN DIANE M
IPC: C12Q1/68
Filed: 2003-12-17
Abstract: Disclosed is a Single Condition Amplification/Internal Primer (SCAIP) sequencing method which allows for the rapid, accurate, and economical analysis of any large multi-exon gene. The method can be used to detect genomic mutations in any large multi-exon gene including the dystrophin gene.  In some forms, the method can rely on amplification of a large number of exons at a single set of PCR temperatures with a first set of amplification primers followed by sequencing without optimization of individual amplicon conditions, using a second, internal set of sequencing primers. The SCAIP method provides for the identification and analysis of specific individual genomic mutations such as deletions, point mutations, frameshifts, or combinations thereof, in gene complexes with multiple exons/introns spanning large genomic regions.
Patent CA-2510921-A1 (CA)
Inventor: DRAPER ALEXANDER D
IPC: A63C10/26
Filed: 2003-12-04
Abstract: La présente invention se rapporte à une fixation (10) comportant une sangle talonnière de suspension (34) formée par un élément supérieur (62) raccordé pivotant à la base (60) de la structure de fixation (16). La sangle talonnière (34) se plie ou se déplace de manière contrôlée par rapport à la base de fixation (28) au niveau de l'extrémité talon de la fixation (10). Une fixation dotée de la sangle talonnière de suspension (34) facilite les manoeuvres et améliore le contrôle sur la planche, ce qui permet à un néviplanchiste d'améliorer ses performances, ladite fixation offrant parallèlement des fonctions d'absorption des chocs et des vibrations qui accroissent le confort global de la fixation en cours d'utilisation.
Patent CA-2517090-A1 (CA)
Inventor: VAN WARNERS ANNE
IPC: B01D53/86
Filed: 2004-01-23
Abstract: The present invention relates to a process for the reducing the amount of SO2 in a SO2 and CO containing gas stream, wherein the gas stream is contacted with a Claus catalyst; a hydrogenation catalyst, and a hydrolysing catalyst.  In a process according to the invention the contacting with the hydrolysing catalyst. In a process according to the invention the contacting with the hydrolysing catalyst is carried out at a temperature below 270~C.
Patent CA-2518617-A1 (CA)
Title: Connector for packings containing medical liquids, and corresponding packing for medical liquids
Inventor: KNIERBEIN BERND
IPC: A61M39/20
Filed: 2004-01-22
Abstract: A connector for packings containing medical liquids, particularly infusion, transfusion or enteral bags, comprises a connecting part (1) for accommodating a spike for drawing out the liquid and comprises a closure part (3) that closes the passage (2) inside the connecting part (1). The connecting part (1) has an elastically deformable pinching off part (4) provided in the form of a tubular section with a non-circular cross-section. A base part (5), which widens on both sides is adjoined to said pinching off part (4) and can be integrated in the packing. During manufacturing, the packing is filled with liquid via the connecting part. After filling, the pinching off part is pressed together whereby preventing liquid from escaping. Afterwards, the closure part is placed onto the connecting part. The manufacturing of the packing is simplified by virtue of the fact that an additional tube for connecting the connector and packing is rendered unnecessary.
Patent CA-2525382-A1 (CA)
Title: Method of and system for directional drilling
Inventor: MAIDLA ERIC E
IPC: E21B7/06
Filed: 2004-05-06
Abstract: A method of and system for directional drilling reduces the friction between the drill string (35) and the well bore (33). A downhole drilling motor (41) is connected to a drilling rig (11) at the surface by a drill string (35). T he drilling motor (41) is oriented at a selected tool face angle. The drill string (35) is rotated at the surface in a first direction until a first torque magnitude is reached without changing the tool face angle. The drill string (35) is then rotated in the opposite direction until a second torque magnitude is reached, again without changing the tool face angle. The drill string is rotated back and forth between the first and second torque magnitudes. Pressure inside the drill string is measured, and the first and second torque magnitudes are adjusted in response to changes in the pressure .
Patent CA-2525976-A1 (CA)
Inventor: WILSON LINDA K
IPC: C12P19/34
Filed: 2003-05-23
Abstract: Cette invention se rapporte à des compositions et à des procédés relatifs à des polynucléotides d'ARN à faible interférence (ARNsi), pour la modulation de la transduction de signaux biologiques. Ces polynucléotides d'ARNsi interfèrent avec l'expression de l'enzyme PTP1B qui est un membre de la classe des enzymes protéine-tyrosine-phosphatases (PTP) servant de médiateurs dans la transduction des signaux. Dans certains modes de réalisation préférés, l'ARNsi module les voies de transduction de signaux comprend l'enzyme PTP-1B humaine ou murine et, dans d'autres modes de réalisation, le récepteur de l'insuline et/ou la protéine Jak2. La modulation de la transduction de signaux biologiques à médiation par l'enzyme PTP1B est utile dans des maladies associées à des défaillances de la prolifération cellulaire, de la différenciation cellulaire et/ou de la survie des cellules telles que les troubles métaboliques (y compris le diabète et l'obésité), le cancer, les maladies auto-immunitaires, les troubles infectieux et inflammatoires et d'autres états pathologiques.
Patent CA-2526574-A1 (CA)
Title: Stretch wrap films
Inventor: PERDOMI GIANNI
IPC: C08L23/10
Filed: 2004-05-19
Abstract: A stretchable wrap film comprising a polymer blend comprising (percent by weight): I) 50 to 90% of an ethylene polymer composition comprising a recurring unit derived from an ester selected from (1) ethylenically unsaturated organic monomer of esters of unsaturated C3-C20 monocarboxylic acids and C1, to C24 monovalent aliphatic or alicyclic alcohols, and (2) vin yl esters of saturated C2-C18 carboxylic acids, wherein the ester content rangi ng from 2.5 to 8 wt% based on the total weight of the final ethylene polymer composition; the ethylene polymer composition having a density ranging from 0.920 to 0.94 g/mL; and II) 10 to 50% of an ethylene-based polymer component having a density ranging from 0.9 to 0. 93 0 g/mL and a melt flow rate up to 4 g/ 10 min. The stretchable wrap film has a ratio between the value of MD tea r resistance and the value of TD tear resistance over 0.3 and a value of MD tensile strength at 30% ranging between 6.5 to 15 N. The stretchable film is suited for use as stretch, cling wraps in various bundling, packaging and wrapping operations.
Patent CA-2526947-A1 (CA)
Inventor: SCHMUCK FRANK
IPC: B62D25/20
Filed: 2004-05-18
Abstract: The invention relates to a jack bracket (12) for a motor vehicle, which is fixed to a sill of the motor vehicle with flanges and an opening (16) for a receiving element in which the jack is placed. The invention also relates to a method for the production of said bracket (12). In order to simplify the production and configuration of the bracket (12) without comprising its stability, the bracket (12) is comprised of a tubular hollow profile (6) and a lid (13), which is fixed on the end (10) opposite the sill of the hollow profile (6) covering said end (10) and which has the opening (16) for the receiving element.
Patent CA-2527432-A1 (CA)
Inventor: HIMMER THOMAS
IPC: B05D5/00
Filed: 2005-11-21
Abstract: The present invention relates to hard coating of ferrous metal substrates using a laser beam with diamond particles in a metal matrix produced from precursor powders of metals which bond to the diamond particles and to the ferrous substrate. The hard coating is particularly useful for white iron castings for pumps (200) used in piping tar sand and water mixtures.
Patent CA-2530835-A1 (CA)
Title: Reversible cooking appliance
Inventor: WANAT DAVID J
IPC: A47J37/00
Filed: 2004-06-30
Abstract: A cooking appliance (1) is provided. The cooking appliance (1) has a heating plate (10) with at least one cooking surface (12), a heater (14) for heating the heating plate, a support structure (16) for supporting the heating plate, and an interface mechanism (46) that, in response to the heating plate being positioned on the support structure in a predetermined position, is actuated to permit heating of the heater.
Patent CA-2531107-A1 (CA)
Title: Inhibitors of histone deacetylases for the suppression therapy of diseases
Inventor: MARTIN ELKE
IPC: A61K31/4436
Filed: 2004-06-23
Abstract: The present invention relates to the use of compounds acting as inhibitors of enzymes having histone deacetylase activity for the medical therapy of conditions which predispose a person for the development of a disease, such as but not limited to cancer, inflammatory or metabolic diseases. Such conditions are linked to genetically inherited mutations of crucial genes which predispose a person with this condition to develop the disease phenotype.  Thus, the invention relates to the use of such compounds for a suppressive therapeutic approach - the SUPPRESSION THERAPY - in order to inhibit or delay the onset or progression of the genetically predisposed disorder. Furthermore, the invention includes the manufacture of a clinically used medicament for the SUPPRESSION THERAPY of such inherited predisposing conditions.
Patent CA-2532184-A1 (CA)
Inventor: RUEDIGER CLAUS
IPC: B29C48/11
Filed: 2004-07-02
Abstract: The invention relates to a multi-layered product which is produced by coextrusion. The coextruded side thereof can be recognised more easily. Said product comprises a base layer containing transparent thermoplastic and at least one coextrusion layer which is different from the base layer, said coextrusion layer containing transparent thermoplastic. The invention also relates to a method for the production of said multi-layered product, and products which contain said multi-layered product.
Patent CA-2532195-A1 (CA)
Inventor: ANCHEYTA JUAREZ JORGE
IPC: C10G65/12
Filed: 2003-07-09
Abstract: The invention relates to a method for the catalytic hydroprocessing of heavy petroleum hydrocarbons with a high concentration of contaminants (metals and asphaltenes), which is performed at low-pressure operating conditions, together with the type of reactor and the type of feedstock. The invention limits the formation of sediments and sludge in the product and can be used to produce a hydrotreated hydrocarbon with improved properties and with contaminant, API gravity and distillate levels which fall within the ranges commonly reported for standard feedstock for refining schemes.
Patent CA-2533682-A1 (CA)
Title: Expandable trailer
Inventor: DI FRANCO BENITO
IPC: B62D63/06
Filed: 2006-01-23
Abstract: An expandable trailer comprising a chassis, at least one pair of extendab le supports, at least one pair of horizontal floor sections and at least one pa ir of floor elements. Each support is extendable laterally outwardly to a respecti ve side of a central longitudinal axis of the chassis. The horizontal floor sections of each pair of horizontal floor sections are spaced apart laterally and each have an outer rail which is coupled to a corresponding one of the supports. The floo r elements are pivotally coupled to each other and to the floor sections. Upon extension of the extendable supports from a retracted position to an open, extended position, the horizontal floor sections move laterally outwardly to extend from the chassis and the floor elements move from an upright vertical arrangement to an arrangement where the floor elements lie in horizontal alignment with the floor sections.
Patent CA-2535161-A1 (CA)
Title: Pipette for disposable tips of different size
Inventor: SCHWAB JUERGEN
IPC: B01L3/02
Filed: 2006-02-02
Abstract: The present invention is directed to a pipette comprising mounting surfaces of different diameter for the use of disposable tips of different size, which allows to easily discarding the tips after use. Such pipettes can be used in manual and automatic pipetting systems.
Patent CA-2539327-A1 (CA)
Inventor: KARAMANOS JOHN C
IPC: A45F5/10
Filed: 2004-09-17
Abstract: The invention is a mounting bracket having a body and an arm coupled to the body and a method of transporting conduits supported to the bracket. A support guide is located within the arm and is configured to receive a pipe and provide support to the pipe. A base is coupled to the body and is configured to attach to a platform. The base is ftirther configured to provide support to the body. A handle is coupled to the body and is configured to maneuver the bracket, wherein the bracket is configured to maintain support for the pipe while the bracket is maneuvered by the handle.
Patent CA-2540035-A1 (CA)
Inventor: VAN DAM MICHAEL
IPC: C08J5/00
Filed: 2004-09-23
Abstract: A functionalized photocurable perfluoropolyether is used as a material for fabricating a solvent-resistant microfluidic device. Such solvent-resistant microfluidic devices can be used to control the flow of small amounts of a fluid, such as an organic solvent, and to perform microscale chemical reactions that are not amenable to other polymer-based microfluidic devices.
Patent CA-2540094-A1 (CA)
Inventor: KERRY JOHN
IPC: G02B6/44
Filed: 2004-09-30
Abstract: A cable lead out device (10) suitable for use within a bore (13) through a wall (60), the device comprising a body to guide a cable, the cable having a minimum permitted bend radius, along a passageway in the bore, the passageway being defined by the body and extending in an arc from a first point within the bore via the mouth of the bore to a second point outside of the bore, wherein the first point is sited within the bore at a location so that the cable guided along the passageway arcs substantially at its minimum permitted bend radius. The device (10) consists of a tube portion (12), a neck (26) having an engaging end (24), a horn portion (14) having an arc-shaped passageway (15) and a terminating end (16). The device (10) is suitable for electrical and optical cables.
Patent CA-2543273-A1 (CA)
Title: Two-piece garment
Inventor: MARQUIS NOEMI
IPC: A41D27/00
Filed: 2006-04-13
Abstract: A garment assembly for a human body comprising a first garment element and a second garment element. The first garment element comprising a top end having a first neck opening, left and right lateral sides having left and right first arm openings respectively, a front side, a back side having an opening, and a bottom end. The second garment element comprising a top end having a second neck opening, left and right lateral sides having respective left and right second arm openings respectively, a front side having an opening, a back side, and a bottom end. When assembling the first and second garment elements on a human body, the first and second neck openings provide for the neck of the human body to be placed therethrough, the first garment element front side covers the front of the human body, the second garment element back side covers the back of the human body. The left first and second arm openings provide for the left arm of the human body to be placed therethrough and the right first and second arm openings provide for the right arm of the human body to be placed therethrough.
Patent CA-2544435-A1 (CA)
Inventor: ANDERSON PETER M
IPC: G01N27/18
Filed: 2004-11-01
Abstract: Ignitable vapor sensing systems and methods are disclosed. An appliance such as a gas water heater, clothes dryer, and the like can be associated with a controller for controlling the appliance. A vapor sensor is also associated with the appliance, such that the vapor sensor comprises an active sensor and an error sensor, wherein the active sensor generates an active signal and the error sensor generates an error signal (e.g. amient atmosphere without an ignitable vapor present). An amplifier is also associated with the vapor sensor, such that the amplifier subtracts the error signal from the active signal to generate a compensated signal indicative of the presence of an ignitable vapor within a vicinity of the appliance and thereby instruct the controller to shut down the appliance.
Patent CA-2544525-A1 (CA)
Title: Emulsifier blend replacement for natural sodium sulfonates in metalworking applications
Inventor: KALHAN SANJAY
IPC: C09K23/12
Filed: 2004-11-12
Abstract: Synthetic alkyl arenesulfonates in combination with the salt of a coupled reaction product of (A)(I) high-molecular weight polycarboxylic acylating agent, said acylating agent (A)(I) having at least one hydrocarbyl substituent having an average of from about 20 to about 500 carbon atoms, and at least one (B)(I) low-molecular weight polycarboxylic acylating agent, said acylating agent (B)(I) optionally having at least one hydrocarbyl substituent having an average of about 6 to about 19 carbon atoms, being coupled together by (C) at least one compound having (i) two or more primary amino groups, (ii) two or more secondary amino groups, (iii) at least one primary amino group and at least one secondary amino group, (iv) at least two hydroxyl groups or (v) at least one primary or secondary amino group and at least one hydroxyl group.  These salt compositions are useful as emulsifiers in oil-in-water emulsions useful as functional fluids.
Patent CA-2544741-A1 (CA)
Inventor: JUNG MARTIN
IPC: A01N37/46
Filed: 2004-11-05
Abstract: The invention relates to compounds of the general formula (I) wherein X, Y and W have the significances given in claim 1 and optionally the enantiomers thereof. The active ingredients have advantageous pesticidal properties. They are especially suitable for controlling parasites in and on warm-blooded animals.
Patent CA-2546377-A1 (CA)
Title: Method of purifying pravastatin
Inventor: KERI VILMOS
IPC: A61K31/225
Filed: 2004-11-23
Abstract: The present invention provides pure pravastatin compositions and pure compactin compositions, and methods for the preparation thereof.
Patent CA-2546610-A1 (CA)
Inventor: PARK JASON
IPC: G06K9/00
Filed: 2004-11-19
Abstract: A two-pass mail sorting method for sorting mail into delivery point order. In one embodiment, the method includes the step of forming a delivery point group comprising delivery points that are temporarily or permanently on hold. In another embodiment, the method includes the step of processing saturation mail only after performing the first-pass mail sort. In another embodiment, the method includes partitioning a mail sorting system comprising N outputs into X  virtual mail sorting systems having N/X outputs.
Patent CA-2547790-A1 (CA)
Inventor: PANCHERI ITALO
IPC: F04D25/04
Filed: 2004-12-01
Abstract: A suction pump (1) for lifting equipment, having an air intake device (2) for drawing in air through an intake port (2a); an electric motor (3) for rotating the air intake device (2); and a pneumatic motor (4) which is connected to the air intake device (2) by a free-~wheel connecting device (5) to rotate the air intake device (2) in place of the electric motor (3).
Patent CA-2550361-A1 (CA)
Title: Compounds and methods for development of ret modulators
Inventor: IBRAHIM PRABHA
IPC: A61K31/44
Filed: 2004-12-17
Abstract: Compounds active on Ret are described, as well as methods of using such compounds. Also described are crystal structures of Ret surrogates that were determined using X-ray crystallography. The use of such Ret surrogate crystals and strucural information can, for example, be used for identifying molecular scaffolds and for developing ligands that bind to and modulate Ret and for identifying improved ligands based on known ligands.
Patent CA-2550596-A1 (CA)
Title: 3-cycloalkylaminopyrrolidine derivatives as modulators of chemokine receptors
Inventor: HAN AMY QI
IPC: A61K31/4439
Filed: 2004-12-16
Abstract: The present invention relates to 3-cycloalkylaminopyrrolidine derivatives of the formula 1: (wherein R1, R2, R3, R4, R5, R6, R7, X, Y and Z are as defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of chemokine receptors and more specifically as modulators of the CCR2 and/or CCR5 receptor. The compounds and compositions of the invention may bind to chemokine receptors, e.g., the CCR2 and/or CCR5 chemokine receptors, and are useful for treating diseases associated with chemokine, e.g., CCR2 and/or CCR5, activity, such as atherosclerosis, restenosis, lupus, organ transplant rejection and rheumatoid arthritis.
Patent CA-2553386-A1 (CA)
Inventor: RIDGWAY RICHARD W
IPC: G02F1/21
Filed: 2005-01-12
Abstract: Optical devices (10, 40) are provided for optical signal modulation of light propagating in a waveguide core surrounded by polymeric cladding regions which include chromophores, under the control of an electrical signal propagating along a traveling wave electrode structure. The microwave electrode structure comprises a coplanar stripline including a control signal electrode (75) interposed between a pair of ground plane electrodes (72, 74). Each of the microwave ground plane electrodes is connected to a positive or negative DC  bios source (+Vblas, -Vbias) and is coupled from the microwave signal input (44) by means of DC blocking capacitors (76). The ground electrode portions (72~, 74~) isolated from the signal input and output can be used to align the chromophores by applying a bias voltage at a temperature near the glass transition temperature of the polymer. The present invention also contemplates provision of a coplanar stripline as described and claimed herein.
Patent CA-2554259-A1 (CA)
Title: Emulsifiable concentrate comprising a dinitroaniline compound
Inventor: GIOIA PAUL
IPC: A01N25/22
Filed: 2005-01-28
Abstract: The invention relates to an emulsifiable concentrate comprising an active ingredient being a dinitroaniline compound, preferably selected from the group consisting of pendimethalin, trifluralin and mixtures thereof. The emulsifiable concentrate of the invention avoids crystallization at low temperature when the concentration of the active ingredient is high.  Accordingly, the emulsifiable concentrate comprises a diester co-~solvent having the following formula R1OOC-(CH2)n-COOR2, wherein R1 and R2, identical or different, are C1-C10, preferably C1-C6, linear or branched, alkyl, aryl, alkaryl or arylalkyl groups, and n is an average number of from 2 to 4.
Patent CA-2560078-A1 (CA)
Inventor: CUI JIANJUN
IPC: A61H7/00
Filed: 2004-04-15
Abstract: The invention relates to a massage prophylactic and therapy appliance, which includes a suction head and a handle. The end of the suction head is in the form of a round flat opening. A blowhole is set on the wall of the handle. During the course of using the appliance, first, put the suction head snugly on the eyeball in order to vent the air of the suction head. Then, negative pressure is produced in the suction head by nipping the blowhole. When a hand grasps, or nips, the blowhole, a negative air pressure is produced. The handle is then pushed and pulled resulting in the suction head tip attracting the eyelid and eyeball and causing same to move back and forth. The suction head sucks the eyelid and the eyeball, and moves forward and backward by pulling forward and pushing backward the handle. Because the eyeballs are controlled by 6 extraoculars, when they are pulled and pushed, there will be a little distortion of the eyeballs. With this distortion, there will be a strong massage to the ciliary muscle. So the ciliary muscle will relax and get back to regulate normally. Then the eyes will relieve, so the utility model is convenient and effective.