Patent GB-575004-A (GB)
Title: Pest control compositions and methods
Filed: 1943-10-18
Abstract: 2-Thiazolinyl sulphides are prepared by reacting a 2-mercaptothiazoline with an organic halide or sulphate in the presence of an alkali.  The reaction may be carried out in water, alcohols or dry hydrocarbon solvents.  The reaction may also be effected in anhydrous conditions using the dry sodium salt of 2-mercaptothiazoline.  Examples describe the preparation of octyl-, bexamethylene-, bis-, benzyl-, 2 : 4 : 6-trichlorbenzyl-dodecyl-, and "Lorol" 2-thiazolinyl sulphides from 2-mercaptothiazoline and octyl bromide, hexamethylene dibromide, benylchloride, 2 : 4 : 6-trichlorbenzyl chloride, dodecyl bromide, and "Lorol" chloride respectively.ALSO:Insecticidal, fungicidal and disinfectant compositions contain as an essential active ingredient a 2-thiazolinyl sulphide, preferably one in which a carbon atom of an organic radicle is linked through sulphur to the 2-position, in admixture with one or more other ingredients of the kind usually used in pesticidal compositions, namely pulverulent or liquid carriers or diluents, or insect bait materials, and if desired with one or more other toxicant compounds.  The preferred 2-thiazolinyl sulphides include octyl-, benzyl-, hexamethylene-bis-, 2:4:6-trichlorobenzyl-, dodecyl-, "Lorol"-(Registered Trade Mark), benzoyl-, dodecyl-, acetyl-, secondary butyl-and methyl- 2-thiazolinyl sulphides and 2-thiazolinyl thiobenzoate.  Reference is also made to the use of 4-methyl-, 4:5 dimethyl-, 4-propyl-, 5-isopropyl, 5-butyl-, and 4-beta-hydroxyethyl- 2-thiazolinyl sulphides and to compounds in which the other sulphide radical may be phenyl, 2:4 dinitrophenyl, p-chlorophenyl; cyclohexyl, alkyl in the range from methyl to octadecyl, mixed radicals such as carbmethoxy, ethoxymethyl, butoxymethyl, betabutoxyethoxyethyl, carbethoxymethyl, propionyl, valeryl, and p-nitrobenzoyl.  The compositions may be in the form of aqueous sprays, dusts or solutions, dispersed with wetting agents such as the alkali or amine salts of oleic acid and the sulphated higher alcohols, the sulphonated animal or vegetable oils such as fish or castor oil or sulphonated petroleum oils; with diluents such as calcium phosphate, Bancroft clay, kaolin, diatomaceous earth, sulphur, lime, pyrophyllite, talc, bentonite, flours such as shell, walnut, wheat, redwood, soya bean, cottonseed, bran and molasses; or with organic solvents such as trichlorethylene, tetrachlorethylene and other hydrocarbon solvents; or in vegetable and mineral oil sprays in which petroleum or vegetable oil glycerides are used as contact agents or active poisons.  Various adhesive and sticking materials such as rosin and glue and adjuvants such as lime and sodium sulphate may be used.  The other toxicants which may be present include arsenates, fluosilicates, phenothiazines, organic thiocyanates such as n-dodecyl thiocyanate and butyl carbitol thiocyanate, nicotine, anabasine (neo-nicotine), novnicotine, rotenone and its congeners, hellibore, pyrethrum, N-isobutylundecylenamide, aminomethyl sulphides, sulphur, polysulphides (lime-sulphur), chlorinated phenols, copper acylacetonates, copper chelates of B-keto acids and esters or of salicylaldehyde, Burgundy mixture, Bordeaux mixture, basic copper sulphates, oxychlorides, oxides, silicates, zeolites and thiocyanates, copper calcium chlorides, long chain quaternary ammonium halides and derivatives of dithiocarbamic acid such as ferric dimethyldithio-carbamate.  2-Thiazolinyl sulphides are prepared by reacting a 2-mercaptothiazoline with an organic halide or sulphate in the presence of an alkali.  The reaction may be carried out in water, alcohols or dry hydrocarbon solvents.  The reaction may also be effected in anhydrous conditions using the dry sodium, salt of 2-mercaptothiazoline.  Examples describe the preparation of octyl-, hexamethylene-bis-, benzyl-, 2:4:6-trichlorbenzyl-, dodecyl-, and "Lorol"-, 2 thiazolinyl sulphides from 2-mercaptothiazoline and octyl bromide, hexamethylene dibromide, benzyl chloride, 2:4:6 trichlorbenzyl chloride, dodecyl bromide, and "Lorol" chloride respectively.