baber/WOPTO huggingface dataset:
Patent WO-2021154746-A1 (WO)
Title: Joint optimization of radionuclide and external beam radiotherapy
Inventor: OLCOTT PETER DEMETRI
IPC: A61N5/10
Filed: 2021-01-26
Abstract: Disclosed herein are methods for radiotherapy treatment plan optimization for irradiating one or more target regions using both an internal therapeutic radiation source (ITRS) and an external therapeutic radiation source (ETRS). One variation of a method comprises iterating through ITRS radiation dose values and ETRS radiation dose values to attain a cumulative dose that meets prescribed dose requirements. In some variations, an ITRS is an injectable compound that has a targeting backbone and a radionuclide, and images acquired using an imaging compound that has the same targeting backbone as the injectable compound can be used to calculate the radiation dose deliverable using the injectable ITRS, and also to calculate firing filters for delivering radiation using a biologically-guided radiation therapy (BGRT) system. Image data acquired from a previous treatment session may be used to adapt the dose provided by an ITRS and/or ETRS for a future treatment session.
Patent WO-2021154838-A1 (WO)
Title: Modular networks with dynamic routing for multi-task recurrent modules
Inventor: CHENG WEI
IPC: G06N3/08
Filed: 2021-01-27
Abstract: Methods and systems for training a neural network model include training (404) a modular neural network model (100), which has a shared encoder and one or more task-specific decoders, including training one or more policy networks that control connections between the shared encoder and the one or more task-specific decoders in accordance with multiple tasks. A multitask neural network model (120) is trained (404) for the multiple tasks, with an output of the modular neural network model and the multitask neural network model being combined to form a final output.
Patent WO-2021173429-A1 (WO)
Title: Fibre optique polymère à revêtement supérieur accordable et stable à l'hydrolyse
Inventor: WHITE WHITNEY
IPC: G02B6/02
Filed: 2021-02-19
Abstract: L'invention concerne une fibre optique polymère qui présente une stabilité hydrolytique améliorée. Cette fibre comprend une âme optique polymère et une couche de gainage, entourée par une couche de gainage polymère qui est constituée d'un mélange miscible d'un ou de plusieurs polymères amorphes hydrolytiquement stables. En faisant varier les rapports des polymères composants dans le mélange de surgainage, la température de transition vitreuse et le coefficient de dilatation thermique de la couche de gainage peuvent être ajustés pour optimiser l'atténuation et la largeur de bande de la fibre optique en plastique.
Patent WO-2021173702-A1 (WO)
Inventor: KIM HYOUNJEONG
IPC: A61P35/00
Filed: 2021-02-24
Abstract: Methods of treating a cancer or a tumor in a subject using a composition are provided. The composition includes a therapeutically effective amount of 2,4-disulfonyl a-phenyl tert-butyl nitrone (2,4-ds-PBN) or pharmaceutically acceptable salts thereof, wherein the therapeutically effective amount decreases a growth of the cancer or the tumor.
Patent WO-2021178923-A1 (WO)
Inventor: HU MIN
IPC: C12Q1/6825
Filed: 2021-03-05
Abstract: The invention relates generally to a sensor for detecting an analyte of interest in a sample including a CRISPR system that cleaves a target nucleic acid sequence when the analyte contacts the sensor, thereby producing a detectable signal indicative of the presence of the analyte.
Patent WO-2021178965-A1 (WO)
Inventor: GHOSH INDRANEEL
IPC: C12Q1/68
Filed: 2021-03-08
Abstract: A method to produce novel split-protein sensors are described herein. The method implements a sequence dissimilarity (SD) based design that can identify potential split-sites in proteins to generate a split-protein pair, and then employs structure guided mutagenesis of the fragmented protein interface to generate split-protein sensors. The sensors have a signal to background ratio > 200 and can be readily used to monitor protein-protein interactions and their inhibition in cells.
Patent WO-2021183676-A1 (WO)
Title: Braided medical device and method
Inventor: OSLUND JOHN
IPC: A61B17/122
Filed: 2021-03-10
Abstract: A method for making a neutral hybrid braided structure may involve positioning a first set of wires on a braiding machine in a first set of positions, positioning a second set of wires on the braiding machine in a second set of positions so that the first set of positions and the second set of positions form a neutral hybrid braiding pattern, and braiding the first set of wires and the second set of wires on the braiding machine to form the neutral hybrid braided structure. Each wire in the first set of wires has a first cross-sectional diameter, and each wire in the second set of wires has a second cross-sectional diameter that is smaller than the first cross-sectional diameter.
Patent WO-2021188834-A1 (WO)
Inventor: ANDREWS JASON
IPC: C40B40/06
Filed: 2021-03-18
Abstract: Provided herein,  inter alia , are methods of detecting single polypeptide polymorphisms in a subject by detecting a G191A NAT2 SNP, a C282T NAT2 SNP, a T341C NAT2 SNP, a G590A NAT2 SNP and a G857A NAT2 SNP in a biological sample, wherein the subject is taking an arylamine drug or a hydrazine drug or the subject is in need of an arylamine drug or a hydrazine drug. The subject can have a tuberculosis infection and the drug can be isoniazid. Also provided are related kits.
Patent WO-2021195075-A1 (WO)
Title: Provisionnement de snpn et obtention de services de snpn d'un plmn
Inventor: STARSINIC MICHAEL
IPC: H04W48/18
Filed: 2021-03-23
Abstract: Selon la présente invention, un équipement utilisateur (UE) fonctionnant dans un " mode de provisionnement " peut rechercher des informations de capacité de provisionnement de diffusion réseau (OCT), puis s'enregistrer à l'aide de justificatifs d'identité de provisionnement et recevoir des justificatifs d'identité SNPN du réseau. L'UE peut ensuite sortir du mode de provisionnement, entrer dans un mode de sélection manuelle de réseau ou de sélection automatique de réseau, et se connecter au SNPN. Un UE peut également recevoir d'un réseau une liste de PLMN et de SNPN qui sont équivalents puis, lors de l'enregistrement, indiquer au réseau qu'une tranche demandée n'est pas associée au HPLMN de l'UE, mais est associée à un SNPN. Le réseau peut indiquer à l'UE la manière dont les tranches de la carte de réseau correspondent aux tranches du SNPN, et peut indiquer si une tranche qui est offerte par le réseau correspond seulement partiellement à une tranche du SNPN ou du HPLMN.
Patent WO-2021202967-A1 (WO)
Title: Power distribution system for 3 phase balanced loads
Inventor: GILL DAVID C
IPC: H04R27/00
Filed: 2021-04-02
Abstract: A power distribution system including a first and second speaker is provided. The first speaker includes (1) a first input receiving a first power signal; (2) a second input receiving a second power signal phase shifted 120 degrees from the first signal; (3) a third input receiving a third power signal phase shifted 120 degrees from both the first and second signal; (4) a first output transmitting the third power signal; (5) a second output transmitting the first power signal; (6) a third output transmitting the second power signal; and (7) a first load coupled to the first and second input. The second speaker includes (1) a first input receiving the third power signal; (2) a second input receiving the first power signal; (3) a third input receiving the second power signal; and (4) a second load coupled to the first and second input.
Patent WO-2021216440-A1 (WO)
Inventor: GUO JIANHUA
IPC: C07D239/93
Filed: 2021-04-19
Abstract: The present disclosure describes novel protein kinase inhibitors and methods for preparing them. The pharmaceutical compositions comprising such protein kinase inhibitors and methods of using them for treating cancer and other diseases, conditions, or disorders, which respond to the inhibition of epidermal growth factor receptor (EGFR), anaplastic lymphoma kinase (ALK) activity, or a combination thereof, are also described.
Patent WO-2021222507-A1 (WO)
Inventor: HE ZHIGANG
IPC: C12N5/0797
Filed: 2021-04-29
Abstract: The invention features methods and compositions that are useful for the treatment of diseases, disorders, conditions, or injuries characterized by insufficient myelination. The methods involve administering GPR17 antagonists and microglia inhibitors or ablation agents.
Patent WO-2021226254-A1 (WO)
Title: Self-rescue swim fin belt
Inventor: O'NEILL CHARLES RYAN
IPC: A63B31/11
Filed: 2021-05-05
Abstract: In one aspect, the invention provides a swim fin (10) comprising a foldable fin blade (26) and foot enclosure, and means for releasably securing the foot of a user within said foot enclosure (22) when in use for swimming. When not in use for swimming, the fin is collapsed to demonstrate a substantially flat form and interconnected with another such swim fin to form a loop structure that can be worn as a belt or bandolier, or stored flat and carried within a fanny pack. The combination swim fin belt apparatus allows a user to carry a pair of swim fins conveniently, comfortably and unobtrusively while engaging in activities that take place on or near the water. The fins are thus immediately available to be deployed for swimming, in particular when the user unexpectedly needs to swim long distances or in challenging conditions without the aid of water safety devices.
Patent WO-2021231353-A1 (WO)
Title: Systems and methods for state identification and classification of text data
Inventor: JAW DAVID
IPC: G06F16/24
Filed: 2021-05-11
Abstract: The present disclosure provides systems and methods for identifying one or more states of a text string describing an event and classifying the event based on the one or more identified states. A method of this disclosure comprises receiving a text string describing an event, transforming the text string into modellable data, analyzing the word composition in the transformed data to identify one or more states of the event, and classifying the event based on the identified states.
Patent WO-2021237027-A1 (WO)
Title: Method and apparatus for joining together modular candle filters
Inventor: DECKER JENS
IPC: B01D46/00
Filed: 2021-05-21
Abstract: A system for forming a hollow modular candle filter includes: a first filter portion having at least one open end; a hollow second filter portion having at least one open end; a sleeve configured to fit within the open end of the first filter portion and the open end of the second filter portion; and an adhesive configured to bind the sleeve to each of the first filter portion and the second filter portion.
Patent WO-2021242679-A1 (WO)
Title: Reinforced structure having continuous fiber reinforced elements and method of making thereof
Inventor: FUNCK RALPH
IPC: B29D99/00
Filed: 2021-05-24
Abstract: Disclosed are reinforced structures. The structures are comprised of reinforced elements that have continuous fibers embedded in a matrix material. The reinforced elements are combined in a matrix material to form a desired shape of reinforced structure.
Patent WO-2022260672-A1 (WO)
Title: A low footprint resource sharing hardware architecture for crystals-dilithium and crystals-kyber
Inventor: BECKWITH LUKE
IPC: H04L9/30
Filed: 2021-06-10
Abstract: A low footprint resource sharing hardware architecture that is implemented as a co-processor and is operably configured to perform a plurality of cryptographic algorithms for Dilithium-DSA at all NISTrecommended post-quantum cryptography security levels and a plurality of cryptographic algorithms for Kyber-KEM at all NIST-recommended post-quantum cryptography security levels. The architecture also includes a singular arithmetic unit (104) operably configured perform all arithmetic operations required in the plurality of cryptographic algorithms for Kyber-KEM and the plurality of cryptographic algorithms for Dilithium-DSA and a singular sampling unit operably configured to sample all vectors and matrices required in the plurality of cryptographic algorithms for Kyber-KEM and the plurality of cryptographic algorithms for Dilithium-DSA.
Patent WO-2021252879-A1 (WO)
Title: Compositions and methods for delivering pharmaceutical agents
Inventor: MANSOUR HEIDI M
IPC: A61F2/02
Filed: 2021-06-11
Abstract: Provided herein are compositions and methods for delivering pharmaceutical agents. In particular, provided herein are hydrogel formulations of suramin for use in wound healing, wound prevention, and other applications.
Patent WO-2021257967-A1 (WO)
Title: Procédé et appareil de traitement oncomagnétique
Inventor: HELEKAR SANTOSH
IPC: A61N2/12
Filed: 2021-06-18
Abstract: L'invention concerne des procédés de traitement du cancer et un appareil, et notamment des traitements anticancéreux non invasifs utilisant des champs magnétiques oscillants (OMF) pour perturber la fonction mitochondriale ou induire l'apoptose ou un autre mécanisme de mort cellulaire dans des cellules cancéreuses. L'invention concerne également un dispositif pour appliquer un traitement par OMF à un sujet.
Patent WO-2022010793-A1 (WO)
Title: Nasal hygiene compositions, antimicrobial treatments, devices, and articles for delivery of same to the nose, trachea and main bronchi
Inventor: DEVLIN THOMAS
IPC: A61M15/00
Filed: 2021-07-02
Abstract: Salt-based non-therapeutic hygienic formulations or compositions or therapeutic formulations or compositions, for example those rich in calcium, are effective against airborne pathogens and toxins, suppressing shedding, for instance by increasing a surface viscoealasticity of airway lining fluid. Associated apparatus, methods and articles are used to deliver salt-based non-therapeutic hygienic formulations or compositions as hygienic treatments to the upper respiratory tract. Associated apparatus, methods and articles are used to deliver salt-based therapeutic antimicrobial formulations or compositions to the upper respiratory tract. For example, nasal delivery of calcium-rich salines with aerosol droplet size of around 10 μm (e.g., 7 μm -15 μm, or more preferably 9 μm - 10 μm) may advantageously limit distribution to the nose and upper airways of the respiratory tract, suppressing bioaerosol generation. A nebulizer may deliver the aerosol into free space, or into a partially enclosed volume, and the composition naturally inspired by one or more subjects.
Patent WO-2022015930-A1 (WO)
Title: Fabrication technique for forming ultra-high density integrated circuit components
Inventor: LIN XI-WEI
IPC: H01L27/11
Filed: 2021-07-15
Abstract: A method for forming ultra-high density integrated circuitry, such as for a 6T SRAM, for example, is provided. The method involves applying double patterning litho-etch litho-etch (LELE) and using a spacer process to shrink the critical dimension of features. To improve process margins, the method implements a double-patterning technique by modifying the layout and splitting cross-coupling straps into two colors (e.g., each color corresponds to a mask-etch process). In addition, a spacer process is implemented to shrink feature size and increase the metal-to-metal spacing between the two cross-coupling straps, in order to improve process margin and electrical performance. This is achieved by depositing a spacer layer over an opening in a hardmask, followed by spacer etch back. The opening is thus shrunk by the amount of spacer thickness. The strap-to-strap spacing may then be increased by twice the amount of spacer thickness.
Patent WO-2022016027-A1 (WO)
Title: Fluid injection system with illuminated fluid reservoir
Inventor: DAHLGREN ARON DAVID
IPC: A61M5/142
Filed: 2021-07-16
Abstract: A fluid injection system includes an injector housing, a sleeve, and a lighting assembly. The sleeve is coupled to the injector housing and is configured to receive and secure a fluid reservoir. The lighting assembly is coupled to the injector housing. The lighting assembly includes a light source configured to illuminate an interior of the fluid reservoir by directing light emitted by the light source into the fluid reservoir.
Patent WO-2022026507-A1 (WO)
Inventor: REZVANITABAR AHMAD
IPC: H03H7/38
Filed: 2021-07-28
Abstract: Systems and methods are disclosed for improving broad bandwidth performance of CMUT elements and arrays using negative capacitance-based impedance matching. The disclosed systems and methods provide a controllable compromise balance between electrical power transfer, acoustic reflectivity, and signal-to-noise ratio. Certain implementations utilize active control of impedance network parameters based on a DC bias input to the CMUT. Instead of minimizing electrical reflection, acoustic reflectivity is controlled to provide improved SNR-bandwidth. Negative capacitance-based matching is tunable to accommodate collapsed mode CMUTs where capacitance and frequency response changes significantly with DC bias.
Patent WO-2022040252-A1 (WO)
Title: Scale resistant backcheck valve
Inventor: OH SHAO CHONG
IPC: F16K15/06
Filed: 2021-08-18
Abstract: A gas lift valve is provided with increased longevity, reliability for preventing backflow, and/or scale resistance. A wide cylindrical sliding member stabilizes axial movement of a valve element in the gas lift valve. A wide spring around the sliding member biases the valve element toward closure during back flow. The spring is physically supported and guided by the sliding member and protected from gas flow injection by the same sliding member. A poppet shape of the valve element provides a consistent closing seal, and the sliding member protects the valve seat and poppet from full force of an injected gas.
Patent WO-2022051484-A1 (WO)
Title: Method and composition for pathogen inhibition utilizing engineered crystalline structures
Inventor: LO ERWIN
IPC: C11D1/62
Filed: 2021-09-02
Abstract: An engineered crystalline structure created from a solution containing silica dioxide that is applied on a surface and dries forming a barrier coating on the treated surface. The formed of the barrier coating has proven to be an effective antimicrobial barrier solely with inert ingredients. Moreover, the established barrier has been shown to eradicate SARS-CoV-2 within two hours without chemical intervention. When applied to a surface and allowed to dry, a 4-6 nm crystalline-like layer of silica dioxide bonds covalently to the surface. The crystalline-like structures making up the "new" surface are invisible to the naked eye but can be observed via a high-powered electronic microscope. Once silica dioxide is applied to a surface, the crystalline-like structures contain spikes that penetrate the outer membranes and protein coats of microorganisms, rendering them dead in the case of bacteria and fungi or inactive in the case of viruses.
Patent WO-2022067258-A1 (WO)
Inventor: KUNZ LARISSA
IPC: A01G9/14
Filed: 2021-09-28
Abstract: In some embodiments, there may be provided a luminescent material or a persistent luminescent (PersL) material that is used to redistribute sunlight. Related systems, methods, and articles of manufacture are also disclosed.
Patent WO-2022125203-A1 (WO)
Inventor: DUTTA Sourjya
IPC: H04B7/06
Filed: 2021-10-26
Abstract: La présente invention concerne, selon certains aspects, un appareil, des procédés, des systèmes de traitement, et des supports lisibles par ordinateur pour une découverte non autonome de liaison latérale. Un équipement d'utilisateur (UE) peut être capable de fonctionner dans deux plages de fréquences distinctes ou plus. Dans une des plages de fréquences distinctes, la découverte de liaison latérale peut imposer un surdébit pesant du fait de la nature de la mise en forme de faisceau dans les plages de fréquences élevées. Les communications dans une autre plage de fréquences plus basses peuvent effectuer une signalisation pour aider à la découverte, réduisant ainsi le surdébit. Par exemple, les UE peuvent utiliser la communication à basse fréquence pour effectuer un alignement de faisceau et une découverte avec un plus faible surdébit de signalisation. De plus, l'UE peut signaler la capacité dans une première plage de fréquences en utilisant des signatures ou des indications figurant dans une communication dans une seconde plage de fréquences. Par exemple, l'UE peut utiliser FR2 pour signaler une capacité dans FR1, notamment en utilisant des pilotes de faisceau comme signatures pour indiquer une capacité dans FR1.
Patent WO-2022094445-A1 (WO)
Inventor: ZIEGLER MARTIN
IPC: C12P13/04
Filed: 2021-11-02
Abstract: Dans divers aspects et modes de réalisation, la présente invention concerne des souches bactériennes modifiées ayant un génome modifié qui offre des avantages dans des processus de maintenance et de biosynthèse lorsqu'on les cultive à grande échelle. La présente invention concerne également des procédés de fermentation à grande échelle dans lesquels on utilise les souches bactériennes. Dans divers modes de réalisation, l'ingénierie des souches permet de réduire les réponses cellulaires aux stimuli micro-environnementaux imposés dans les bioréacteurs à grande échelle.
Patent WO-2022132645-A1 (WO)
Title: Génomique spatiale avec une résolution au niveau monocellulaire
Inventor: DELLEY CYRILLE
IPC: C12Q1/6837
Filed: 2021-12-13
Abstract: La présente invention concerne des matériaux et des procédés pour le séquençage d'un échantillon de tissu et permettant de recueillir des informations concernant l'organisation spatiale du tissu par des approches de séquençage au niveau monocellulaire.
Patent WO-2022147216-A1 (WO)
Title: Dispositif de tomographie assistée par ordinateur à appui de poids
Inventor: CARMODY CLAYTON
IPC: A61G15/10
Filed: 2021-12-30
Abstract: Dispositif (100) pour appui de poids simulé sur le pied et la cheville d'un patient (102), le dispositif (100) comprenant une plaque de base (108) conçue pour recevoir une jambe du patient (102). La plaque de base (108) comprend une partie base (114), une plaque de pied (116) et une plaque de mollet réglable (140). Le dispositif (100) comprend en outre une ceinture destinée à la taille (112) conçue pour être portée par le patient (102) et un appareil de pesage (110) conçu pour relier sélectivement la plaque de base (108) et la ceinture destinée à la taille (112). Le dispositif (100) pour appui de poids simulé sur le pied et la cheville d'un patient (102) peut être utilisé dans un procédé d'utilisation du dispositif (100) pour un appui de poids simulé sur le pied et la cheville d'un patient à l'aide d'un dispositif d'imagerie (104).
Patent WO-2021179019-A1 (WO)
Inventor: FOWLER CAMERON
IPC: G06Q30/00
Filed: 2021-03-07
Abstract: A system for displaying customized mobile content to users at a venue via a user device, includes a server system in conjunction with a plurality of machine-readable codes mounted within the venue. The server system performs the following steps: providing mobile content in a database; collecting user data associated with the user; receiving a request from one of the user devices, the request being generated by scanning one of the machine-readable codes with the user device; determining the user data associated with the user who scanned the machine-readable code; selecting, based upon the user data, customized mobile content from the mobile content in the database; and providing the customized mobile content to the user device.
Patent WO-2022082130-A1 (WO)
Inventor: Ghadiok Vaibhav
IPC: G01C22/02
Filed: 2021-07-21
Abstract: L'invention concerne des systèmes et des procédés pour détecter des violations de trafic à l'aide d'un ou plusieurs dispositifs de détection mobiles. Des vidéos capturées par un ou plusieurs dispositifs de détection mobiles peuvent être traitées sur les dispositifs de détection mobiles pour extraire des données et des informations concernant une violation de trafic potentielle impliquant un véhicule et une zone de route restreinte. Les dispositifs de détection mobiles peuvent transmettre ces données et ces informations à un serveur conçu pour déterminer si une violation de trafic s'est produite par comparaison des données et des informations reçues des dispositifs de détection mobiles.