baber/WOPTO huggingface dataset:
Patent AU-667038-B2 (AU)
Title: LHRH antagonists and intermediate products
Inventor: THAMM PAUL
IPC: C07D295/145
Filed: 1992-05-22
Granted: 1996-03-07
Abstract: PCT No. PCT/DE92/00427 Sec. 371 Date May 4, 1994 Sec. 102(e) Date May 4, 1994 PCT Filed May 22, 1992 PCT Pub. No. WO92/20711 PCT Pub. Date Nov. 26, 1992.The invention concerns LHRH antagonists of the general formula (I), X-X1-X2-X3-L-Ser-L-Tyr-X6-L-Leu-X8-L-Pro-X10 (I) The invention concerns LHRH antagonists of the general formula (I), in which X is an acyl group, X1 is a D-Nal, X2 is D-(4-Cl)-Phe, X3 is D-(3)-Pal, X6 is D-Cit or D-Neu, X8 is L-Arg or L-Neu, at least one of the groups X6 and X8 being a Neu, and X10 is D-Ala-NH2, Neu being a group of formula (II), (IV), (IX) or (X), wherein W is one of the group (a)-(d). The invention includes drugs containing a compound of formula (I), plus the usual auxiliaries and carriers. These drugs are suitable for use in cases of carcinoma of the prostate and in endometriosis, as well as for fertility control.
Patent AU-761814-B2 (AU)
Title: Process for packaging high profile products in a modified atmosphere with an upwardly formed heat shrinkable film
Inventor: STOCKLEX H WALKER III
IPC: B65B31/02
Filed: 1999-12-08
Granted: 2003-06-12
Abstract: A packaging process is disclosed which includes the steps of providing a tray, providing an upper film which includes a sealant layer which is sealable to the tray, orienting the film to an orientation ratio of from about 6.0:1 to about 16.0:1, positioning a high profile product on the tray, extending the upper film above the tray and product, drawing the upper film into a concavity by differential pressure, maintaining the concave shape of the upper film while heating the film, removing gases from the space between the upper film and the tray and product, introducing a desirable gas into the space, releasing the upper film such that it shrinks toward the product and the tray while the desirable gas is retained within the space and prevents close contact of the film with the lowermost portions of the product, and sealing the upper film to the flange of the tray, wherein at least the step of heating the film shrinks the film, thereby tensioning it onto and across the underlying product. The resultant package of the high profile product provides an in-store overwrap appearance.
Patent AU-662343-B2 (AU)
Title: Method of extracting sennosides A, B and A1
Inventor: CARCASONA ALFONS
IPC: A61K36/482
Filed: 1992-06-24
Granted: 1995-08-31
Abstract: The invention concerns a method of extracting sennosides A, B and A1. The method comprises the following steps: a sennoside mixture is reduced to the corresponding anthrone-8-glucosides, the aloe-emodin components are removed by liquid-liquid separation of the anthrone-8-glucosides, and the rheine-9-anthrone-8-glucoside obtained after the separation step is oxidized again to sennosides A, B and A1. The invention also concerns sennosides A, B and A1 obtained by this method and pharmaceutical agents containing them.
Patent AU-702852-B2 (AU)
Title: Method and recognizer for recognizing a sampled sound signal in noise
Inventor: FINEBERG ADAM B
IPC: G10L15/20
Filed: 1997-03-06
Granted: 1999-03-04
Abstract: A sound recognizer uses a feature value normalization process to substantially increase the accuracy of recognizing acoustic signals in noise. The sound recognizer includes a feature vector device which determines a number of feature values for a number of analysis frames, a min/max device which determines a minimum and maximum feature value for each of a number of frequency bands, a normalizer which normalizes each of the feature values with the minimum and maximum feature values resulting in normalized feature vectors, and a comparator which compares the normalized feature vectors with template feature vectors to identify one of the template feature vectors that most resembles the normalized feature vectors.
Patent AU-614094-B2 (AU)
Title: Multi-stage process for reducing the concentration of pollutants in an effluent
Inventor: EPPERLY WILLIAM ROBERT
IPC: B01D53/34
Filed: 1988-08-12
Granted: 1991-08-22
Abstract: A process is presented for reducing the concentration of pollutants in an effluent from the combustion of a carbonaceous fuel. The process comprises introducing a first treatment agent into the effluent at a first temperature zone to reduce the concentration of a first pollutant and introducing a second treatment agent into the effluent at a second temperature zone to reduce the concentration of either the first pollutant or a second pollutant, wherein the first and second treatment agents are introduced under conditions effective to reduce the effluent pollution index.
Patent AU-702220-B2 (AU)
Title: Manufacture of autogenous replacement body parts
Inventor: KHOURI ROGER K
IPC: A61L27/36
Filed: 1995-06-02
Granted: 1999-02-18
Abstract: Disclosed are matrix materials, methods, and devices for manufacture in vivo of autogenous replacement body parts comprising plural distinct tissues. In one embodiment, the replacement body part is a skeletal joint and the new plural distinct tissues include bone and articular cartilage.
Patent AU-605002-B2 (AU)
Title: Apparatus and process for producing high density thermal spray coatings
Inventor: MOSKOWITZ LARRY NEIL
IPC: B05B7/20
Filed: 1988-12-21
Granted: 1991-01-03
Abstract: An attachment for supersonic thermal spray equipment by which inert shield gas is directed radially outwardly about the central core of a supersonic, particle-carrying flame to isolate the same from ambient atmosphere. The shield gas is injected tangentially against the inner surface of a constraining tube attached to and extending from the discharge end of the thermal spray gun nozzle, causing the shield gas to assume a helical flow path which persists until after it exits the tube and impacts the work piece. A process using the shielding apparatus with a high-velocity, thermal spray gun and employing oxygen and hydrogen as gases of combustion and inert gas to introduce metal powder, having a narrow particle size distribution and low oxygen content, into the high-velocity combustion gases, produces significantly improved, high-density, low-oxide metal coatings on a substrate.
Patent AU-707717-B2 (AU)
Title: Tri-substituted phenyl derivatives useful as PDE IV inhibitors
Inventor: WARRELLOW GRAHAM JOHN
IPC: C07C1/26
Filed: 1995-06-21
Granted: 1999-07-15
Abstract: Compounds of general formula (1) are described:wherein=W- is (1) =C(Y)- where Y is a halogen atom, or an alkyl or -XRa group where X is -O-, -S(O)m- [where m is zero or an integer of value 1 or 2], or -N(Rb)- [where Rb is a hydrogen atom or an optionally substituted alkyl group] and Ra is a hydrogen atom or an optionally substituted alkyl group or, (2) =N-;L is (1) a -C(R)=C(R1)(R2) or [-CH(R)]nCH(R1)(R2) group; is (2) a -(Xa)nAlk'Ar', or Alk'XaAr' group; or is (3) XaR1;Z is a group (A), (B), (C) or (D): whereinAr is a monocyclic or bicyclic aryl group optionally containing one or more heteroatoms selected from oxygen, sulphur or nitrogen atoms;Z1is a group -NR12C(O)- [where R12 is a hydrogen atom or an optionally substituted alkyl or (Alk)tAr group], -C(O)NR12-, -NR12C(S)-, -C(S)NR12-, -C=C-, -NR12SO2-, or -SO2NR12-;Alk is an optionally substituted straight or branched alkyl chain optionally interrupted by an atom or group X;t is zero or an integer of value 1, 2 or 3;R3 is a hydrogen or a fluorine atom or an optionally substituted straight or branched alkyl group or an OR11 group [where R11 is a hydrogen atom or an optionally substituted alkyl, alkenyl, alkoxyalkyl, alkanoyl, formyl, carboxamido or thiocarboxamido group];R4 is a hydrogen atom or an optionally substituted alkyl, -CO2R8, -CSNR9R10, -CN, -CH2CN, or -(CH2)tAr group where t is zero or an integer of value 1, 2 or 3 and Ar is a monocyclic or bicyclic aryl group optionally containing one or more heteroatoms selected from oxygen, sulphur or nitrogen atoms; provided that when L is a group of type (2) or (3) above then Z is a group of type (A) or type (B) in which R4 is a -(CH2)tAr group;R5 is a group -(CH2)tAr;R6 is a hydrogen or a fluorine atom, or an optionally substituted alkyl or -CO2R8, -CONR9R10, -CSNR9R10, -CN or -CH2CN group;R7 is a hydrogen or a fluorine atom, an optionally substituted straight or branched alkyl group, or an ORc group where Rc is a hydrogen atom or an optionally substituted alkyl or alkenyl group, alkoxyalkyl, alkanoyl, formyl, carboxamido or thiocarboxamido group; and the salts, solvates, hydrates, prodrugs and N-oxides thereof.Compounds according to the invention are phosphodiesterase type IV inhibitors and are useful in the prophylaxis and treatment of disease such as asthma where unwanted inflammatory response or muscular spasm is present.
Patent AU-610975-B2 (AU)
Title: Biological sensors
Inventor: FINLAN MARTIN FRANCIS
IPC: G01N21/55
Filed: 1989-01-26
Granted: 1991-05-30
Abstract: A biological sensor which utilises the phenomenon of surface plasmon resonance to detect the refractive index change which occurs when two components - for example antibody and corresponding antigen - react with one another. Surface plasmon resonance takes place at the sloping exit surface of an optical waveguide such as a fibre optic 23. The input end of fibre optic 12 is connected to a light source 12. A layer 25 of metal is applied to the sloping exit surface so as to cause total internal reflection of the light proceeding down the fibre optic. Reflected light is detected by a detector 13. A sensitive, for example antibody, layer 26 is applied to the metal layer. Sample (not shown) reacts with layer 26 in such a way that the refractive index changes. Provided conditions are correct, this variation in refractive index can be monitored in detector 13 by virtue of the surface plasmon resonance which occurs in the area of total internal reflection.
Patent AU-667204-B2 (AU)
Title: Triazolopyrimidine derivatives
Inventor: PEES KLAUS-JURGEN
IPC: A01P3/00
Filed: 1992-12-24
Granted: 1996-03-14
Abstract: This invention relates to certain triazolopyrimidine derivatives of the general formula <CHEM> in which R<3> represents an optionally substituted aryl group and Hal represents a chlorine or bromine atom, and processes for their preparation.
Patent AU-674500-B2 (AU)
Title: Recombinant bone morphogenetic protein heterodimers, compositions and methods of use
Inventor: ISRAEL DAVID
IPC: C12N5/071
Filed: 1992-11-02
Granted: 1997-01-02
Abstract: The present invention relates to a methods for producing recombinant heterodimeric BMP proteins useful in the field of treating bone defects, healing bone injury and in wound healing in general. The invention also relates to the recombinant heterodimers and compositions containing them.
Patent AU-605084-B2 (AU)
Title: Dust collection in sintering of metallurgical products
Inventor: SCHMIDT HERMANN
IPC: B03C3/013
Filed: 1989-03-01
Granted: 1991-01-03
Abstract: To improve the precipitation efficiency of electrofilters in sintering plants, it is proposed to carry out an exhaust gas conditioning using solid particles and to tap off some of the quantity of coke breeze needed as fuel for the sintering process for this purpose, grind it separately, introduce it into the quantities of exhaust gas to be freed from dust, and finally to precipitate it with the dust in the electrofilters and return it to the sintering process. 
<IMAGE>
Patent AU-689627-B2 (AU)
Title: Divider panel for stacked cans
Inventor: CAMPBELL GEOFFREY
IPC: B65D71/70
Filed: 1995-08-09
Granted: 1998-04-02
Abstract: PCT No. PCT/GB95/01876 Sec. 371 Date May 27, 1997 Sec. 102(e) Date May 27, 1997 PCT Filed Aug. 9, 1995 PCT Pub. No. WO96/05120 PCT Pub. Date Feb. 22, 1996A divider panel for stacked cans is disclosed. The divider panel has an elongate paperboard strip (10) which includes a plurality of divider pads (12), each divider pad providing two rows of can seats (11) defined therein for being disposed between two layers of vertically stacked cans. The divider pads are connected along their ends to adjacent ones of the divider pads along perforated lines (13) to assist in separating the divider pads from one another as desired. The use of the elongate divider panel of this invention allows for lower operating speeds in placing the divider panel on a generally continuous lower layer of cans prior to placing the upper layer of cans thereon as the divider panel and the cans move along a path of travel on a packaging machine when compared to sequentially placing one of a series of separate divider pads between the pairs of cans otherwise being moved along the path of travel on the packaging machine at a relatively faster rate of speed. The divider panel of this invention can be used with a variety of arrays of cans.
Patent AU-624810-B2 (AU)
Title: Acyl derivatives
Inventor: ALBRECHT HARRY ALLEN
IPC: C07D501/46
Filed: 1989-03-30
Granted: 1992-06-25
Abstract: Acyl derivatives of the general formula <IMAGE>  in which R<1> denotes a substituted N-heterocycle of the formulae <IMAGE> in which R<1><0> represents one of the groups <IMAGE> and Q represents a substituted quinolinyl or naphthyridinyl group, where the N-heterocycle can optionally be substituted by one or more lower alkyl groups; and in which R<2> additionally represents hydrogen, lower alkoxy, lower alkylthio or lower alkanoylamino, R<3> represents an acyl group, m represents 0, 1 or 2 and A represents a pharmaceutically tolerable anion, and easily hydrolysable esters and pharmaceutically tolerable salts of these compounds and hydrates of the compounds of the formula I or of their esters and salts and a process for their preparation and pharmaceutical preparations which contain this compound, and also intermediates for the preparation of these compounds, and additionally the use of the compounds for the control of diseases and for the production of the preparations mentioned are described. The products have antibiotic activity.
Patent AU-615279-B2 (AU)
Title: Skin moisturizing composition and method of preparing same
Inventor: GERIA NAVIN MANOHAR
IPC: A61K8/92
Filed: 1989-03-31
Granted: 1991-09-26
Abstract: A long lasting, esthetically pleasing skin care moisturizing composition comprising   (1) an oil phase comprising oil from about 30% to about 80% and a non-ionic surface active agent having an HLB number of about 7 to about 12, wherein the non-ionic surface active agent is present in an amount of about 5% to about 9%; (2) an aqueous phase comprising an aqueous thickening agent from about 0.05% to about 5% and water from about 15% to about 65% wherein the oil phase is added to the aqueous phase to form an emulsion has been developed. The method of preparation of the composition and a method of treating skin with the composition are also disclosed. m
Patent AU-710204-B2 (AU)
Title: Artificial mismatch hybridization
Inventor: GUO ZHEN
IPC: C12Q1/68
Filed: 1997-06-05
Granted: 1999-09-16
Abstract: An improved nucleic acid hybridization process is provided which employs a modified oligonucleotide and improves the ability to discriminate a control nucleic acid target from a variant nucleic acid target containing a sequence variation. The modified probe contains at least one artificial mismatch relative to the control nucleic acid target in addition to any mismatch(es) arising from the sequence variation. The invention has direct and advantageous application to numerous existing hybridization methods, including, applications that employ, for example, the Polymerase Chain Reaction, allele-specific nucleic acid sequencing methods, and diagnostic hybridization methods.
Patent AU-737618-B2 (AU)
Title: Human DNase I hyperactive variants
Inventor: LAZARUS ROBERT A
IPC: A61K38/00
Filed: 1997-06-09
Granted: 2001-08-23
Abstract: The present invention relates to amino acid sequence variants of human DNase I that have increased DNA-hydrolytic activity. The invention provides nucleic acid sequences encoding such hyperactive variants, thereby enabling the production of these variants in quantities sufficient for clinical use. The invention also relates to pharmaceutical compositions and therapeutic uses of hyperactive variants of human DNase I.
Patent AU-763373-B2 (AU)
Title: Production of palladium-103
Inventor: WEBSTER BRIAN A
IPC: G21G1/10
Filed: 1999-04-20
Granted: 2003-07-17
Abstract: Palladium-103 radiochemical of high radionuclidic purity can be produced in commercial scale quantities by irradiating enriched Palladium targets comprising a mixture of Pd isotopes with protons or deuterons in the 10-50 MeV energy range. Commercially viable batch sizes with acceptable specific activity of the product Pd-103 are achieved by adjusting the irradiation energy, irradiation time, irradiation current, current density, plated target mass, plated target shape, plated target size, target isotope enrichment levels, and incident angle of the target to the beam. The method for the production of Pd-103 comprises providing a target material enriched with Pd isotopes comprising atomic masses equal to or greater than Pd-103, applying the target material onto a target support; irradiating the target material with protons or deuterons of sufficient incident energy and time to convert at least some of the Pd isotopes within the target material to Pd-103; and purifying Pd from the non-Pd components.
Patent AU-726843-B2 (AU)
Title: Bladder water gun, improved bladder and nozzle
Inventor: ANDRADE BRUCE M D
IPC: B05B1/34
Filed: 1997-06-27
Granted: 2000-11-23
Abstract: An expandable bladder toy water gun (1) is provided. It includes a main housing (3) having a barrel (9), a water ejection nozzle (11), a handle (5), a trigger (7), a water storage tank (33), a hand pump (45) as well as an inflatable bladder (13) connected to the main housing (3). The pump (45) is connected to both the tank (33) and the bladder (13). There is a bladder release valve (31) with an upstream side connected to the bladder (13) and a downstream side connected to the nozzle (11) for water ejection when the trigger (7) is pulled. The elasticity of the bladder (13) is used as the motive force for liquid ejection. The bladder is a tubular member which has a section (91) of weakened elastic strength relative to the remainder of the member. In one embodiment, the bladder has a variable diameter, larger at its front end and smaller at its back end. In another embodiment, the bladder has a constant diameter with a wall thickness gradient. The nozzle (11) includes a turbulence control member (213) for enhanced laminar flow ejection which control member has a plurality of linear stream guidance walls.
Patent AU-768988-B2 (AU)
Title: A process for the purification of roxithromycin
Inventor: HEGGIE WILLIAM
IPC: C07H1/06
Filed: 1999-07-16
Granted: 2004-01-15
Abstract: A process for the purification of roxithromycin, an antibiotic for therapeutic purposes, in which the purification is carried out by the dissolution or suspension of the product in methanol followed by cooling. Purification may also be obtained by addition of a non-solvent and/or by concentration of the mixture, thus obtaining a purified product.
Patent AU-672793-B2 (AU)
Title: Pharmaceutical composition containing cyclosporin derivative
Inventor: MEINZER ARMIN
IPC: A61K38/00
Filed: 1993-04-20
Granted: 1996-10-17
Abstract: A pharmaceutical composition containing ([3'-desoxy-3'-oxo-MeBmt]<1>-[Val]<2>-Ciclosporin) as an active ingredient. The composition is formulated as a microemulsion or microemulstion preconcentrate using a carrier medium comprising a hydrophilic phase; a transesterified ethoxylated vegetable oil; and a surfactant. The composition has good stability and biopharmaceutical properties and is useful in the treatment of multiple drug resistance syndrome in humans.
Patent AU-717254-B2 (AU)
Title: Continuous casting process between rolls
Inventor: DAMASSE JEAN-MICHEL
IPC: B22D11/16
Filed: 1997-10-30
Granted: 2000-03-23
Abstract: A detection method of continuous casting between rolls of steel products comprises measuring continuously the roll separation strain (RSF) and a signal representative of the variations in this strain (RSF) generated as a function of time. The signal is used to act upon the roll separation to compensate for any untrue roundness of the rolls. During these measurements the signal is separated into different harmonic components and the resulting comparison of the harmonic components thus obtained with some reference harmonics is representative of the state of defects in the rolls. This state of defects in the rolls allows the definition of different rules for conducting the casting process as a function of the gravity of the roll defects measured.
Patent AU-670599-B2 (AU)
Title: Improved methods and catalysts for the manufacture of carbon fibrils
Inventor: MOY DAVID
IPC: D01F9/127
Filed: 1993-05-12
Granted: 1996-07-25
Abstract: An improved catalyst for producing carbon fibrils is made by incorporating an effective yield-enhancing amount of a carboxylate into a fibril-forming catalyst. Alternatively, such a catalyst is made by coprecipitating a compound of a metal having fibril-forming catalytic properties and an aluminum and/or magnesium compound, optionally in the presence of carbon particles or carbon fibril aggregates. The catalyst may also be made by incorporating a compound of a fibril-forming metal onto magnesia particles in carbon particles or carbon fibril aggregates. The catalysts, methods of using them to form carbon fibrils and those carbon fibrils are also disclosed.
Patent AU-674158-B2 (AU)
Title: Hybrid oligonucleotide phosphorothioates
Inventor: METELEV VALERI
IPC: A61P31/12
Filed: 1993-07-22
Granted: 1996-12-12
Abstract: The invention provides hybrid oligonucleotides having phosphorothioate or phosphorodithioate internucleotide linkages, and both deoxyribonucleosides and ribonueleosides or 2'-substituted ribonucleosides. Such hybrid oligonucleotides have superior properties of duplex formation with RNA, nuclease resistance, and RNase H activation.
Patent AU-727605-B2 (AU)
Title: An elastically deformable osteosynthesis system for the spinal column
Inventor: ELBERG JEAN-FRANCOIS
IPC: A61B17/70
Filed: 1997-11-13
Granted: 2000-12-14
Abstract: The osteosynthesis system has two anchor members (2) adapted to be fixed to two vertebrae (4), and a link member (6; 106) adapted to interconnect the anchor members and to exert stresses against the two anchor members moving towards each other in translation. The link member (6; 106) is elastically deformable in bending about a deformation axis (45, 47, 49). It has two fixing portions (16) adapted to be fixed to the two anchor members (2) and an intermediate portion (40). The intermediate portion is offset from an alignment axis (18) of the two fixing portions (16). The link member (6; 106) has two abutments (39) disposed so as to come into abutment against each other when the link member is deformed about the axis.
Patent AU-645488-B2 (AU)
Title: A process for the generation of proliferating CD4 lymphocytes
Inventor: LEUNG KAM HUNG
IPC: C12N7/02
Filed: 1990-02-08
Granted: 1994-01-20
Abstract: Peripheral blood mononuclear cells (PBMC) or tumor infiltrating lymphocytes (TIL) are treated with a dipeptide alkyl ester such as leucyl leucine methyl ester (LLME) or with an amino acid alkyl ester such as leucine methyl ester (LME) to deplete monocytes and large granular lymphocytes, then cultured in media containing T-cell stimulant and interleukin-2 to generate and proliferate a lymphocyte population enriched in CD4<+> lymphocytes.