Patent EP-1229890-B1 (EP)
Inventor: PRUCHE FRANCIS
IPC: A61K8/36
Filed: 2001-10-09
Granted: 2004-09-15
Abstract: Tinctorial composition improving the natural pigmentation, method for obtaining and using same for skin and/or keratin matters. The composition comprises, in a physiologically acceptable medium, at least one enzyme having a propigmenting activity and an efficient amount of a catalytic system comprising a first component selected amongst salts and oxides of Mn(II) and/or Zn(II) and the mixtures thereof and a second component selected amongst alkaline hydrogenocarbonates, alkaline earth hydrogenocarbonates and the mixtures thereof, the proportions of the first component and the second component being such that:   <math-cwu id="MATH-US-00001"> <number>1</number> <math>   <mrow>     <mfrac>       <mrow>         <mo>[</mo>         <mrow>           <mi>Mn</mi>           <mo>⁡</mo>           <mrow>             <mo>(</mo>             <mi>II</mi>             <mo>)</mo>           </mrow>         </mrow>         <mo>]</mo>       </mrow>       <mrow>         <mo>[</mo>         <msub>           <mi>HCO</mi>           <mn>3</mn>         </msub>         <mo>]</mo>       </mrow>     </mfrac>     <mo>≤</mo>     <mrow>       <mn>1</mn>       <mo>it</mo>       <mstyle>         <mtext> </mtext>       </mstyle>       <mo>it</mo>       <mrow>         <mi>with</mi>         <mo>it</mo>         <mstyle>           <mtext> </mtext>         </mstyle>         <mo>[</mo>         <mrow>           <mi>Mn</mi>           <mo>⁡</mo>           <mrow>             <mo>(</mo>             <mi>II</mi>             <mo>)</mo>           </mrow>         </mrow>         <mo>]</mo>       </mrow>     </mrow>     <mo>≠</mo>     <mn>0</mn>   </mrow> </math> <math>   <mrow>     <mfrac>       <mrow>         <mo>[</mo>         <mrow>           <mrow>             <mi>Z</mi>             <mo>it</mo>             <mi>n</mi>           </mrow>           <mo>⁡</mo>           <mrow>             <mo>(</mo>             <mi>II</mi>             <mo>)</mo>           </mrow>         </mrow>         <mo>]</mo>       </mrow>       <mrow>         <mo>[</mo>         <msub>           <mi>HCO</mi>           <mn>3</mn>         </msub>         <mo>]</mo>       </mrow>     </mfrac>     <mo>≤</mo>     <mrow>       <mn>1</mn>       <mo>it</mo>       <mstyle>         <mtext> </mtext>       </mstyle>       <mo>it</mo>       <mrow>         <mi>with</mi>         <mo>it</mo>         <mstyle>           <mtext> </mtext>         </mstyle>         <mo>[</mo>         <mrow>           <mi>Zn</mi>           <mo>⁡</mo>           <mrow>             <mo>(</mo>             <mi>II</mi>             <mo>)</mo>           </mrow>         </mrow>         <mo>]</mo>       </mrow>     </mrow>     <mo>≠</mo>     <mn>0</mn>   </mrow> </math> <math>   <mrow>     <mfrac>       <mrow>         <mo>[</mo>         <mrow>           <mrow>             <mi>Mn</mi>             <mo>⁡</mo>             <mrow>               <mo>(</mo>               <mi>II</mi>               <mo>)</mo>             </mrow>           </mrow>           <mo>+</mo>           <mrow>             <mi>Zn</mi>             <mo>it</mo>             <mstyle>               <mtext> </mtext>             </mstyle>             <mo>it</mo>             <mrow>               <mo>(</mo>               <mi>II</mi>               <mo>)</mo>             </mrow>           </mrow>         </mrow>         <mo>]</mo>       </mrow>       <mrow>         <mo>[</mo>         <msub>           <mi>HCO</mi>           <mn>3</mn>         </msub>         <mo>]</mo>       </mrow>     </mfrac>     <mo>≤</mo>     <mrow>       <mn>1</mn>       <mo>it</mo>       <mstyle>         <mtext> </mtext>       </mstyle>       <mo>it</mo>       <mrow>         <mi>with</mi>         <mo>it</mo>         <mstyle>           <mtext> </mtext>         </mstyle>         <mo>[</mo>         <mrow>           <mi>Mn</mi>           <mo>⁡</mo>           <mrow>             <mo>(</mo>             <mi>II</mi>             <mo>)</mo>           </mrow>         </mrow>         <mo>]</mo>       </mrow>       <mo>it</mo>