baber/WOPTO huggingface dataset:
Patent NZ-554360-A (NZ)
Title: Pharmaceutical composition for the sustained release of hydralazine and use thereof as a support for cancer treatment
Inventor: ESTRADA FLORES LUIS
IPC: A61K31/498
Filed: 2004-09-09
Abstract: Disclosed is a hydralazine extended release pharmaceutical composition consisting of: a) from 16 to 20% hydralazine hydrochloride as active ingredient; b) from 42 to 44% of a polymer that limits the release rate of said active ingredient wherein said polymer is hydroxypropylmethylcellulose; c) from 25 to 28% of a diluent agent wherein the diluent agent is microcrystalline cellulose; d) from 10% of a release rate-moderating hydrophilic polymer wherein said polymer is pregelatinized starch; and e) from 0.1 to 2% of a lubricant where said lubricant agents is magnesium stearate, or a) from 16 to 20% hydralazine hydrochloride as active ingredient; b) from 44 to 46% of a polymer that limits the release rate of said active ingredient wherein said polymer is hydroxypropylmethylcellulose; c) from 27 to 29% of a diluent agent wherein the diluent agent is microcrystalline cellulose; d) from 10% of a release rate-moderating hydrophilic polymer wherein said polymer is pregelatinized starch; and e) from 0.1 to 2% of a lubricant where said lubricant agents is magnesium stearate. Disclosed is the use of a hydralazine extended release pharmaceutical composition according to any one of claims 1 or 2, in the manufacture of a medicament useful in the treatment of cancer, wherein the releases rates are up to 10.823 mg/h or 10.323 mg/h for 20-22 hours.
Patent NZ-554572-A (NZ)
Title: Fastening tool having a nosepiece and magazine feed
Inventor: CANNALIATO MICHAEL L
Filed: 2005-10-27
Abstract: An actuation member (not shown) connects a trigger 178 to a trigger switch (not shown). A trigger block (not shown) is provided having a blocked position that obstructs the actuation member and an unblocked position that allows the actuation member to actuate the trigger switch.
Patent NZ-554685-A (NZ)
Title: Ground engaging apparatus
Inventor: SULMAN RICHARD
Filed: 2005-09-21
Abstract: Disclosed is a formulation comprising 3-amino-1-propanesulfonic acid, or a salt thereof, and an enteric coating, for oral treatment or prevention of an amyloid-related disease such as Alzheimer's disease, cerebral amyloid angiopathy, inclusion body myositis, macular degeneration, Down's syndrome, mild cognitive impairment, cognitive decline or hereditary cerebral hemorrhage.
Patent NZ-554941-A (NZ)
Title: Transitional alumina particulate materials from boehmite having controlled morphology and processing for forming same
Inventor: BAUER RALPH
IPC: C01F7/441
Filed: 2005-11-18
Abstract: A method for forming alumina particular material comprising: Providing a boehmite precursor and boehmite seeds in a suspension at a weight ratio not less than 60:40, the boehmite precursor comprising hydrated alumina and heat treating the suspension at temperatures greater than 120°C, converting the boehmite precursor in boehmite particulate material and calcining said particulate material to transform it into transitional alumina particulate material having an aspect ratio of not less than 3:1.
Patent NZ-560277-A (NZ)
Title: Polyethylene pipe patching systems and methods
Inventor: GREEN KENNETH H
IPC: B32B25/02
Filed: 2006-01-31
Abstract: A multi-layered patch comprising at least two layers. The first layer is a polymer adhesive layer and the second layer is a polymer support film that becomes intimately incorporated with the first polymer adhesive layer upon application of heat.
Patent NZ-564252-A (NZ)
Title: Polymorphic forms of (s)-1-cyanobutan-2-yl (s)-1-(3-(3-(3-methoxy-4-(oxazol-5-yl) phenyl) ureido) phenyl) ethylcarbamate
Inventor: BLYTHE TODD A
IPC: A61K31/421
Filed: 2006-05-25
Abstract: Disclosed is the polymorphic Form A1 of (S)-1-cyanobutan-2-yl (S)-1-(3-(3-(3-methoxy-4-(oxazol-5-yl)phenyl)ureido)phenyl)ethylcarbamate wherein said polymorph comprises less than about 5 percent by weight of amorphous form and wherein the polymorph has a peak position at about 20.7 degrees 2-theta in an x-ray powder diffraction pattern obtained using Cu K alpha radiation. Also disclosed is the polymorphic Form B2 of (S)-1-cyanobutan-2-yl (S)-1-(3-(3-(3-methoxy-4-(oxazol-5-yl)phenyl)ureido)phenyl)ethylcarbamate, wherein the polymorph has a peak position at about 4.1 degrees 2-theta in an x-ray powder diffraction pattern obtained using Cu K alpha radiation. A process for preparing polymorphic form A1 or B2 is also disclosed. Also disclosed is the use of either polymorphic form A1 or B2 in the manufacture of a medicament for treating IMPDH-mediated diseases in a patient.
Patent NZ-568286-A (NZ)
Title: Solid biocidal compositions comprising a hypohalite and a nitrogen source
Inventor: CHENG HUAI N
IPC: A01N59/00
Filed: 2006-11-22
Abstract: Disclosed is a solid dual agent composition comprising:(a) a solid hypohalite;(b) a solid nitrogen source which is an ammonium salt; and(c) a component which is either:(i) a solid pH control material that has at least one secondary function as a diluent, stabilizer, anti-caking agent, binder or desiccant; or (ii) a combination of a solid pH control material and a solid diluent, solid stabilizer, solid anti-caking agent, solid binder, solid desiccant, or combination thereof; wherein said dual agent composition forms a biocidal mixture when combined with water.
Patent NZ-568402-A (NZ)
Title: Combining data from input channels to form output channels that are not linear combinations of the inputs
Inventor: CHUBAREV PAVEL
IPC: G10L21/0308
Filed: 2006-12-01
Abstract: Disclosed is a method of extracting N audio output channels from two audio input channels. The method comprises: transforming each of the audio input channels into respective input spectra; creating an inter-channel amplitude spectrum from the input spectra; thresholding each spectral line of the interchannel amplitude spectrum into a single one of N outputs; and combining data from the two input channels according to the spectral mappings to form the N audio output channels. The N audio output channels are not linear combinations of the two input channels. A further method of separating Q audio sources from M audio input channels is disclosed that includes mapping nonlinearly each spectral line of the inter-channel amplitude spectra into a single one of Ne"Q outputs to create a map for each output.
Patent NZ-568654-A (NZ)
Title: Method of treating abnormal cell growth
Inventor: CHRISTENSEN JAMES GAIL
IPC: C07D231/10
Filed: 2006-11-23
Abstract: Disclosed is the use of (R)-3-[1-(2,6-dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1h-pyrazol-4-yl)-pyridin-2-ylamine as depicted or a pharmaceutically acceptable salt thereof in the manufacture of a medicament for the therapeutic treatment of abnormal cell growth in a mammal in need of such treatment. Wherein the abnormal cell growth is mediated by anaplastic lymphoma kinase (ALK).
Patent NZ-576966-A (NZ)
Title: A graphical user interface
Inventor: MOONEY DALE EDWARD
IPC: G06T17/40
Filed: 2006-10-13
Abstract: Disclosed is a computer program which perform the steps of: receiving a 3-dimensional representation of a first object; providing a set of controls adapted to allow selections which specify characteristics of a piece of jewellery to be made; and receiving through the set of controls indications of events identifying said selections. The program then generates a 3-dimensional representation of the first object combined with the piece of jewellery and provides a display of the 3-dimensional representation. The representation includes a geometrical mesh representation comprising mesh elements including photographic representations of parts of the first object.
Patent NZ-584200-A (NZ)
Title: Low profile waste fitting with a pop-up plug
Inventor: HAIGH BRIAN
IPC: A47K1/14
Filed: 2010-03-25
Abstract: Disclosed is a waste fitting which includes a plug mounted upon a sprung loaded pop-up cartridge, a mounting plate, and a waste pipe connector. The mounting plate provides a supporting bracket which receives the pop-up cartridge and provides mounting points for supporting screws spaced around the bracket. The supporting screws connect the mounting plate and the waste pipe connector.
Patent NZ-586733-A (NZ)
Title: Method for manufacturing a composite using a mould and an airbag
Inventor: STIESDAL HENRIK
IPC: B29C70/44
Filed: 2009-05-08
Abstract: A method for manufacturing a composite comprises steps of laying at least one fibre mat 12 onto the inner surface of a mould 7, applying suction between the inner surface of the mould 7 and the at least one fibre mat 12, covering the outermost fibre mat 12 of the at least one fibre mat 12 with at least one vacuum bag 5A , introducing vacuum to the region between the vacuum bag 5A and the mould 7, injecting resin under vacuum into the region between the vacuum bag 5A and the mould 7, letting the resin set, and removing the mould 7. A medium which is suitable to distribute vacuum is placed between the inner surface of the mould 7 and the at least one fibre mat 12 and/or between two subsequent fibre mats and is used for applying suction between the inner surface of the mould 7 and the at least one fibre mat 12. The medium is suitable to distribute vacuum is connected to a vacuum pump for applying suction.
Patent NZ-587284-A (NZ)
Title: Use of a type ii anti-cd20 antibody with increased antibody dependent cellular cytotoxicity (adcc) in combination with cyclophosphamide, vincristine and doxorubicine for treating non-hodgkin' s lymphomas
Inventor: DUMONTET CHARLES
IPC: A61P35/00
Filed: 2009-03-23
Abstract: Disclosed is the use of a type II anti-CD20 antibody with increased antibody dependent cellular cytotoxicity (ADCC) for the manufacture of a medicament for the treatment of CD20 expressing cancer in combination with one or more chemotherapeutic agents selected from the group consisting of cyclophosphamide, vincristine and doxorubicine, wherein said type II anti-CD20 antibody is a glycoengineered, humanized B-Ly1 antibody, and the treatment with the type II anti-CD antibody is in combination (a) with cyclophosphamide and vincristine, or (b) with doxorubicine, or (c) with cyclophosphamide, or (d) with cyclophosphamide, vincristine and doxorubicine
Patent NZ-587577-A (NZ)
Title: Method and an Apparatus to Cut Out a Vehicle Glazing Panel
Inventor: FINCK WILLIAM
IPC: B62D65/08
Filed: 2005-09-14
Abstract: A winder unit for use with a cutting wire in cutting out a vehicle glazing panel, the unit having: mounting means for mounting the unit to the glazing panel; first and second winder spools for winding the cutting wire; and, at least one wire wrap around guide element spaced from the winder spools or the mounting means; wherein, in cutting out the glazing panel both winder spools are used to wind in the cutting wire, the winder unit being mounted to the glazing panel during cutting and: the winder unit being repositioned between spaced mounting positions on the glazing panel during the procedure in order to effect cutting out of the glazing panel; and/or one or both spools are provided with a respective ratchet mechanism, the ratchet mechanism being released during the procedure such that the wire becomes slackened.
Patent NZ-587601-A (NZ)
Title: Multivalent Entrain-and-Amplify Immunotherapeutics for Carcinoma
Inventor: BOT ADRIAN
IPC: A61K39/00
Filed: 2006-06-16
Abstract: Provided is an immunogenic product comprising a plurality of compositions comprising: i) a nucleic acid molecule capable of expressing a Melan-A class I MHC restricted epitope, or analogue thereof; ii) a nucleic acid molecule capable of expressing a Tyrosinase class I MHC restricted epitope, or analogue thereof; iii) a peptide consisting essentially of said Melan-A epitope, or analogue thereof; and iv) a peptide consisting essentially of said Tyrosinase epitope, or analogue thereof.
Patent NZ-588905-A (NZ)
Title: Genetic testing method for determining susceptibility to abdominal aortic aneurysm by assay for selected polymorphisms associated with the disease
Inventor: THORGEIRSSON THORGEIR
IPC: C12Q1/68
Filed: 2009-04-01
Abstract: Discloses methods for determining susceptibility to abdominal aortic aneurysm in a human. The method comprises determining the presence or absence of at least one allele of at least one polymorphic marker in a nucleic acid sample obtained from the individual, or in a genotype dataset from the individual. The polymorphic markers consists of polymorphisms within SEQ ID NO:1 within genes CHRN5, CHRNA3 and CHRNB4 that are in linkage disequilibrium and associated with risk of abdominal aortic aneurysm in humans.
Patent NZ-590206-A (NZ)
Title: Wood treatment and treated wood using a silicone emulsion, boron compound and a metal salt
Inventor: WAKAMATSU MASAKI
IPC: A01N25/24
Filed: 2010-12-23
Abstract: Disclosed is a wood comprising in its surface a cured product of a film-forming silicone emulsion composition [I], (F) a boron compound, and (G) a di- or trivalent metal salt, wherein the silicone emulsion composition [I] is a composition comprising the following components (A) to (E) dispersed and emulsified in water, (A) 100 parts by weight of an organopolysiloxane containing at least two silicon-bonded hydroxyl groups on the molecule, (B) 0.5 to 20 parts by weight of the reaction product of an amino-containing organoxysilane and an acid anhydride, (C) 0 to 20 parts by weight of an epoxy-containing organoxysilane and/or partial hydrolyzate thereof, (D) 0 to 50 parts by weight of colloidal silica and/or poly silsesquioxane, and (E) 0 to 10 parts by weight of a curing catalyst, and wherein the boron compound (F) is present in an amount of 10 to 1,500 parts by weight and the di- or trivalent metal salt (G) is present in an amount of 10 to 300 parts by weight per 100 parts by weight of the cured product of film-forming silicone emulsion composition [I], all calculated as solids. Also disclosed is a method of treating wood using the silicone emulsion composition [I], (F) a boron compound, and (G) a di- or trivalent metal salt. Examples of the metal salts are zinc acetate, zinc chloride, calcium acetate and calcium chloride.
Patent NZ-591464-A (NZ)
Title: Change management method including a method of assessing a state of an entity
Inventor: PARRY WARREN JOHN
IPC: G06Q50/00
Filed: 2005-12-20
Abstract: A method of assessing a state of an entity is disclosed. In this method a data generator is used to generate entity data for the entity to be analysed. The entity data includes at least one variable applicable to the entity and the at least one variable comprising a plurality of drivers. Reference data from a processor-based analysis engine is derived. The processor-based analysis engine performs cluster analysis on source data extracted from a database with the source data relating to a state of a community of which the business entity forms a part and the source data relating to a plurality of community variables. The community variables comprise a plurality of community drivers. The entity data is inputted into a computer generated analytical tool to position and track progress of the entity. The computer generated analytical tool comprises an array of cells arranged in at least one of a two dimensional map and a three dimensional mapping and each cell contains a subset of reference data, the reference data within each cell providing a measure of each community driver related to the state of the community and the positioning of the cells relative to one another being governed by the inter-relationship of the reference data contained in the cells. The analytical tool is used to compare the entity data with the reference data to position the entity in that cell of the analytical tool where the values of the subset of the reference data most closely matches the entity variable and to transform the entity data into output data; and the output data is used to analyse the entity to assess and manage change in the entity.
Patent NZ-592296-A (NZ)
Title: Programmable multimedia controller with programmable services
Inventor: MADONNA ROBERT P
IPC: H04N5/00
Filed: 2006-12-20
Abstract: A method of graphically programming a programmable multimedia controller which may be interconnected with one or more components is disclosed. The method comprises the steps of: (a) providing a graphical programming environment which includes a library of one or more component profiles each of which represents a component that may be interconnected with the programmable multimedia controller; (b) using the graphical programming environment to logically interconnect a plurality of selected components with the programmable multimedia controller in a configuration; (c) applying one or more service rules to the configuration to determine which one or ones of a plurality of programmable services are capable of being performed by the plurality of selected components in the configuration; (d) creating a graphical workflow corresponding to each programmable service which is capable of being performed by the configuration and an executable program corresponding to each the graphical workflow; and (e) executing each executable program on the programmable multimedia controller.
Patent NZ-592684-A (NZ)
Title: Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-c]pyridin-3-yl]-1,2-dioxoethyl]-piperazine
Inventor: CHEN CHUNG-PIN H
IPC: C07F9/09
Filed: 2006-12-13
Abstract: Disclosed is a crystalline form of the hemiethanolate of mono-TRIS salt of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-c]pyridin-3-yl]-1,2-dioxoethyl]-piperazine [also known as compound (I)], with an X-ray diffraction pattern as described in the specification.
Patent NZ-594648-A (NZ)
Title: Sustained release oral dosage forms of an r-baclofen prodrug
Inventor: KARABORNI SAMI
IPC: A61K9/20
Filed: 2010-03-03
Abstract: 594648 Disclosed herein is an oral tablet dosage form comprising a tablet and a coating, the tablet comprising: 3 wt-% to 20 wt-% (3R)-4-{ [(1S)-2-methyl-1-(2-methylpropanoyloxy)propoxy) carbonylamino} -3-(4-chlorophenyl)butanoic acid or a pharmaceutically acceptable salt thereof; 15 wt-% to 40 wt-% microcrystalline cellulose; 15 wt-% to 40 wt-% hydroxypropylmethyl cellulose; 3 wt-% to 30 wt-% of a release rate-controlling polymer; and dibasic calcium phosphate dihydrate or dibasic calcium phosphate anhydrous in an amount selected from 19 wt-% to 22 wt-% and 23 wt-% to 33 wt-%; based on the total weight of the dosage form; wherein the release-rate controlling polymer is a poly( ethylacrylate, methyl methacrylate, trimethylammonioethyl methacrylate chloride) copolymer having 8.8% to 12.0% ammonio methacrylate units on a dry substance basis. Additionally disclosed is a method of preparing said oral table dosage form comprising compacting the dry blend formulation to provide an oral tablet dosage form.
Patent NZ-596747-A (NZ)
Title: Crystalline form of pemirolast
Inventor: VIERTELHAUS MARTIN
IPC: C07D471/04
Filed: 2010-06-15
Abstract: 596747 This disclosure relates to a hemihydrate form of the sodium salt of pemirolast which contains between about 0.3 and about 0.7 moles of water per mole or pemirolast. The disclosure also relates to a process to produce this form of pemirolast, a pharmaceutical formulation containing it, the use of this form of pemirolast in the manufacture of a medicament for the treatment of an inflammatory disorder and a method of treatment of an inflammatory disorder in a non-human patient which comprises administrating this form of pemirolast. The inflammatory disorder may be atherosclerosis or an associated cardiovascular disorder. The cardiovascular disorder associated with atherosclerosis is selected from an aortic aneurysm, arteriosclerosis, peripheral arterial occlusive disease, a coronary artery disease, a coronary disease, plaque rupture and/or instability, atheroma rupture and/or instability, a vascular disease, an arterial disease, an ischaemic disease, ischaemia and stroke.
Patent NZ-597040-A (NZ)
Title: A medical container
Inventor: SMART WILLIAM HUGH DAWKINS
IPC: A61B1/12
Filed: 2010-05-14
Abstract: 597040 Disclosed is a housing (20) for use as part of a medical container, such as a cabinet (10), for the dry storage of flexible scopes. The housing (20) has an inlet (22) to allow air to pass into the housing and an outlet (23) to allow air to pass out of the housing, a pump (50) to pump air into the housing via the inlet, and a vacuum (60) to suck air from the housing through the outlet. The housing further comprises an outlet connector connected to the outlet which is connectable to a port of at least one of the scopes, such that, in use, the inside of a medical scope is dried via the vacuum. The outlet connector includes a vacuum pole (40), which extends substantially to the height of the housing.
Patent NZ-598516-A (NZ)
Title: Quinazolines as potassium ion channel inhibitors
Inventor: JOHNSON JAMES A
IPC: C07D403/04
Filed: 2010-09-01
Abstract: Disclosed is a compound of formula I, such as 5-phenyl-N-(pyridine-2-ylmethyl)-2-(pyrimidin-5-yl)quinazolin-4-amine, which is useful for treating arrhythmia, Ikur-associated disorders and other disorders mediated by ion channel function.
Patent NZ-598891-A (NZ)
Title: Synthesis of a neurostimulative piperazine
Inventor: VENKATRAMAN SRIPATHY
IPC: A61K31/4965
Filed: 2010-08-24
Abstract: Disclosed is a method to synthesize a disubstituted piperazines coupled with benzene and nicotinic acid moieties, according to the compounds of formula (I). The method employs piperazine and a substituted nicotinic acid as starting materials and culminates in providing disubstituted piperazine comprising a benzyl substitution at one of the ring nitrogens. The synthesis may further include conversion of this disubstituted piperazine to a suitable salt.
Patent NZ-598956-A (NZ)
Title: Bispecific binding molecules for anti-angiogenesis therapy
Inventor: BORGES ERIC
IPC: C07K16/28
Filed: 2010-10-01
Abstract: Disclosed is a binding molecule comprising a D114-binding component and a VEGF-binding component, wherein said Dll4-binding component is a VHH having an amino acid sequence selected from sequences shown in SEQ ID NOs: 34 and 35 and said VEGF-binding component is a VHH having an amino acid sequence selected from sequences shown in SEQ ID NOs: 42 - 44. The disclosed binding molecule has the following CDR regions according to SYAMA, AIRWSGGTAYYADSVKG, WGQGTLVTVSS, SYSMG, AISXGGXXYDAVSLXG and SRAYGSSRLRLADTYDY
Patent NZ-599718-A (NZ)
Title: A method and device for the treatment of obstructive sleep apnea and snoring
Inventor: SANDERS IRA
IPC: A61F5/56
Filed: 2005-02-28
Abstract: 599718 Disclosed is an implantable tissue retractor for treatment of a breathing disorder. The tissue retractor has a flexible shaft adapted to be disposed in a soft tissue of the tongue located in a patient's oral cavity or pharynx. The tissue retractor has a retractor member connected at or near a first end of the shaft and an anchor member connected at or near a second end of the shaft. The retractor member and the anchor member are configured to be positioned within the soft tissue of the tongue. At least one of the retractor member or the anchor member have a hook shape. The hook shape is configured to interact with the soft tissue without interfering with tongue function to exert a force sufficient to prevent a deformation of at least a portion of an external surface of the soft tissue.
Patent NZ-600292-A (NZ)
Title: Anti-microbial agent from paenibacillus sp. and methods and uses thereof
Inventor: TEATHER RONALD
IPC: A61K8/99
Filed: 2009-12-09
Abstract: Disclosed is an isolated Paenibacillus sp. bacterium comprising SEQ ID NO: 1 isolated from a direct-fed microbial product, wherein the sequence is as defined in the complete specification. Also disclosed is the use of an isolated Paenibacillus sp. bacterium comprising SEQ ID NO:1 isolated from a direct-fed microbial product, in the manufacture of a medicament for inhibiting the growth of a microorganism. Further disclosed is an isolated Paenibacillus polymyxa bacterium deposited at the ATCC® under the terms of the Budapest Treaty and designated Accession Number PTA-10436.