baber/WOPTO huggingface dataset:
Patent DE-69427289-D1 (DE)
Inventor: CHENARD L
IPC: C07D213/74
Filed: 1994-02-15
Granted: 2001-06-28
Abstract: Compounds of formula (I) where R1 is of formulae (II), (III), or (IV), or (V); R2 is -R4, -O-R4, -O-S(O)2-R4, -NR4R5, R4-(CH2)b-NH(C=X)-(CH2)c-, R4-(CH2)b-O(C=O)NH-(CH2)c-(C=O)NH-, R4-(C=O)NH-(C=O)NH-, -(CH2)b-NH(C=X)-(CH2)c-R4, R4-(CH2)b-O(C=O)-(CH2)c-, -(CH2)b-O(C=O)-(CH2)c-R4, -NH(C=X)NH-R4, R4-O(C=O)O-, -O(C=O)NH-R4, R4-O(C=O)NH-, -(CH2)b-(C=O)-(CH2)c-R4, -NH-S(O)2-R4, -C(OH)R4R5, -CH(OH)-R4, -(C=O)-NR4R5, -CN, -NO2, substituted C1 to C6 alkyl, substituted or unsubstituted C1 to C6 alkenyl, or substituted or unsubstituted C1 to C6 alkynyl, said substituted moieties substituted with a moiety of the formulae -R4, -R4R5, -O-R4, or -S(O)d-R4; R3 is hydrogen, C1 to C6 alkyl, C1 to C6 alkylaryl, or aryl; R4 and R5 are each independently (XV), (XVI), (XVII), hydrogen, -CF3, C1 to C6 alkyl, C1 to C6 alkylaryl, with the proviso that when R2 is -R4 or -OR4, R4 is not hydrogen or C1 to C6 alkyl. These compounds are useful psychotherapeutics and are potent serotonin (5-HT1) agonists and antagonists and may be used in the treatment of depression, anxiety, eating disorders, obesity, drug abuse, cluster headache, migraine, pain and chronic paroxysmal hemicrania and headache associated with vascular disorders, and other disorders arising from deficient serotonergic neurotransmission. The compounds can also be used as centrally acting antihypertensives and vasodilators.
Patent DE-69427834-D1 (DE)
Inventor: MAARSCHALKER-WEERD JAN M
IPC: B08B3/02
Filed: 1994-03-04
Granted: 2001-08-30
Abstract: The invention relates to a cleaning apparatus for a radiation source assembly in a fluid treatment system. The invention is characterized in that the cleaning apparatus comprises:   a cleaning sleeve engaging a portion of the exterior of a radiation source in the radiation source assembly and movable between: (i) a retracted position wherein a portion of the radiation source is exposed to a flow of fluid to be treated, and (ii) an extended position wherein the portion of the radiation source is completely or partially covered by the cleaning sleeve, the cleaning sleeve further comprising a chamber in contact with the portion of the radiation source, the chamber adapted for receiving a cleaning fluid suitable to remove undesired materials from the portion of the radiation source upon movement of the cleaning sleeve.     <IMAGE>
Patent DE-69510565-D1 (DE)
Inventor: ENGSTROEM HANS
IPC: F16K31/44
Filed: 1995-07-24
Granted: 1999-08-05
Abstract: PCT No. PCT/SE95/00883 Sec. 371 Date Feb. 3, 1997 Sec. 102(e) Date Feb. 3, 1997 PCT Filed Jul. 24, 1995 PCT Pub. No. WO96/05001 PCT Pub. Date Feb. 22, 1996An apparatus for extracting gases comprises a rotatable reeling drum, a suction hose, a cut-off throttle, a position changing device, and a pivoting means. The position changing device cooperates with the pivoting means to open the cut-off throttle during initial rotation of the reeling drum in a direction of unwinding the suction hose and close the cut-off throttle within a first revolution of the reeling drum in a direction of winding the suction hose.
Patent DE-69517467-D1 (DE)
Inventor: DI SIMONE JOHN
IPC: B29C45/32
Filed: 1995-04-07
Granted: 2000-07-20
Abstract: An injection molding machine (11) having a plurality of axially arranged mold stations (A,B,C,D) including structure for supporting sets of mold plates (19,21;31,32;36,37) and a mechanism for opening, closing and overstroking mold plates. <IMAGE>
Patent DE-69518070-D1 (DE)
Inventor: CHIESI PAOLO
IPC: A61K47/48
Filed: 1995-04-13
Granted: 2000-08-24
Abstract: PCT No. PCT/EP95/01407 Sec. 371 Date Oct. 22, 1996 Sec. 102(e) Date Oct. 22, 1996 PCT Filed Apr. 13, 1995 PCT Pub. No. WO95/28965 PCT Pub. Date Nov. 2, 1995Multicomponent inclusion complexes characterized by the presence of an acidic drug, a base and a cyclodextrin are disclosed. Said complexes have a specific solubility in water.
Patent DE-69519393-D1 (DE)
Inventor: GYORY J RICHARD
IPC: A61N1/30
Filed: 1995-06-29
Granted: 2000-12-14
Abstract: A composition comprises an agent to be delivered through a body surface and an electrotransport enhancer having a hydrophobic tail and a polar head of specific characteristics. An electrotransport delivery device is also provided having a reservoir comprising the agent to be delivered and the electrotransport enhancer of the invention. The electrotransport enhancers increase the electrotransport delivery rate of the agent through the surface while reducing the electrical resistance of the surface during electrotransport of the agent.
Patent DE-69532211-D1 (DE)
Inventor: STEINERT ROGER F
IPC: A61F9/01
Filed: 1995-03-27
Granted: 2004-01-08
Abstract: Accurate, non-mechanical removal of the epithelium from essentially only the area of the cornea to be treated. In particular, an epithelium-ablative laser device irradiates the selected region of the epithelium with ablative laser energy, a spectroscopic system monitors the ablation and spectroscopically determines whether epithelium is being ablated, and a control system terminates the epithelium removal upon spectroscopic determination of a substantial absence of epithelium ablation.
Patent DE-69532512-D1 (DE)
Inventor: MOHSENI ZIA
IPC: A61K8/891
Filed: 1995-04-20
Granted: 2004-03-04
Abstract: Solid shaving compositions comprising a soap base, a humectant (such as glycerin), water, a high molecular weight polyethylene oxide, and a suitable preservative or antioxidant. In preferred formulations, at least one anticorrosion agent is included as part of the composition. If desired, at least one silicone fluid additive, emulsifying agents, fragrances and/or colorants suitable for use in cosmetics or toiletries may also be added. The novel compositions are solids which may be produced in stick form and applied directly to the skin. The solid shaving compositions of the invention provide a desirable balance of properties, making them ideal for use as shaving aids.
Patent DE-69609184-D1 (DE)
Inventor: LIVINGSTON ALAN
IPC: C07H21/00
Filed: 1996-05-16
Granted: 2000-08-10
Abstract: Improved methods for solution-phase synthesis of purified short-chain oligonucleotide coupling units, such as dimers, trimers, and tetramers, suitable for use in solution-phase or solid-phase oligonucleotide synthesis are provided. In one embodiment, there is provided methods of preparing a coupled oligonucleotide, YZ, comprising: (a) providing first nucleotidic segments, Y, in solution, each of the first segments comprising one, two, three, four, six or eight nucleosides, and each of said first segments having a reactive functional group, a, which is a phosphoramidite group; (b) providing a plurality of second nucleotidic segments, Z, in solution, each of said first segments comprising one, two, three, four, six or eight nucleosides, each of said second segments having two non-identical reactive functional groups, b and c, which are a secondary alcohol group and a primary alcohol group, respectively; and (c) reacting said first and second segments in solution to produce a first linkage isomer, YZ-b, which retains a residual secondary alcohol group, b, and a non-identical second linkage isomer, YZ-c, which retains a residual primary alcohol group, c; and (d) reacting a mixture of said YZ linkage isomers, or derivatives thereof, with a selective capping reagent, in solution, whereby said residual secondary alcohol group, b, of said YZ-b linkage isomer remains selectively unchanged, and the residual primary alcohol group, c, of said YZ-c linkage isomer is selectively capped.
Patent DE-69616375-D1 (DE)
Inventor: LANCEL MARIKE
IPC: A61K31/4535
Filed: 1996-07-10
Granted: 2001-11-29
Abstract: The invention relates to a method of treating sleep disorders in a patient in need thereof comprising the administration of a hypnotically effective amount of a non-allosteric GABA<sub>A</sub> agonist.
Patent DE-69622281-D1 (DE)
Inventor: ELIAS JOSEPH
IPC: G06F17/24
Filed: 1996-12-18
Granted: 2002-08-14
Abstract: A form creation and ordering system allows for creation and editing of forms, receives telephone calls placed by users, prompts the users to indicate between one and a predetermined number of desired forms, prompts the users to indicate a selected mode of delivery, and provides the desired forms to the users via the selected mode of delivery. The system may also uniquely identify each of the users by providing identification information, receive user profile data that varies according to the identification information, prompt the users to indicate whether the desired forms should be customized prior to being provided to the users, and customize the desired forms by adding customized user information in response to the users indicating that the desired forms should be customized prior to the forms being provided to the users.
Patent DE-69625930-D1 (DE)
Inventor: FLOYD DAVID
IPC: A61P17/00
Filed: 1996-07-22
Granted: 2003-02-27
Abstract: PCT No. PCT/GB96/01737 Sec. 371 Date Apr. 22, 1998 Sec. 102(e) Date Apr. 22, 1998 PCT Filed Jul. 22, 1996 PCT Pub. No. WO97/03783 PCT Pub. Date Feb. 6, 1997A compound of general formula (I), wherein X is a group of formula (II) or (III), R2, R1, R21, R3, R4, and R5 being as defined in the specification are matrix metalloproteinase inhibitors.
Patent DE-69628454-D1 (DE)
Inventor: SKILLICORN BRIAN
IPC: H01J35/30
Filed: 1996-01-31
Granted: 2003-07-03
Abstract: The x-ray source of the present invention comprises a charged particle beam generator (112) and a vacuum enclosure assembly (176). The charges particle beam generator includes only a single electrical connection (803) for providing high voltage to the electron gun. The generated charged particle beam is controlled through a series of dynamic and static focus coils (187, 185) and moved across the inner face of the target (50) by a stepping coil assembly comprising X and Y deflection coils (190) as well as an X step and preferably Y step coils (188). Further, to minimize power usage a control grid pinches off the charged particle beam during the steppimg of the beam.
Patent DE-69636331-D1 (DE)
Inventor: NAKATA YOSHIE
IPC: B41J2/14
Filed: 1996-01-12
Granted: 2006-08-17
Abstract: An ion beam apparatus comprises a source of ions (1), an evacuatable chamber (11), first and second electrodes (3,5) disposed within the chamber for forming an ion beam from ions from the ion source, the first electrode being electrically insulated from the second electrode. First and second supports for (17,19) supporting said first and second electrodes, respectively, are provided. The apparatus is arranged to allow said electrodes to be moved independently of one another relative to said chamber from outside said chamber. <IMAGE>
Patent DE-69637926-D1 (DE)
Inventor: KAJIWARA SUSUMU
IPC: C07K14/195
Filed: 1996-03-08
Granted: 2009-06-25
Abstract: A DNA chain having characteristic of increasing carotenoid production, and containing the nucleotide sequence which encodes the polypeptide having the substantially same amino acid sequence described in SEQUENCE ID No. 1 or 2, or a DNA chain which hybridizes with said DNA chain, and a method for production for carotenoid characterized by introducing said DNA chain into the carotenoid-producing microorganisms, culturing said transformed microorganism and increasing carotenoid content in the culture broth and cells.
Patent DE-69713121-D1 (DE)
Inventor: CREWS S
IPC: F26B17/00
Filed: 1997-08-27
Granted: 2002-07-11
Abstract: An improved cyclone dryer is disclosed, having an outer cylinder, an inner cylinder, and a cone-shaped chamber. The outer cylinder has a tangential airstream orifice for injecting a high-speed stream of material and air, or other gases, into the dryer. The inner cylinder has a plurality of apertures and a plurality of deflectors that deflect air and material into a cavity defined by the inner cylinder and the cone-shaped chamber. The cone-shaped chamber, the outer cylinder, and the inner cylinder define an annular air chamber. An exhaust assembly is attached proximate the inner and outer cylinders, and is in fluid communication with the cavity.
Patent DE-69725959-D1 (DE)
Inventor: GIAMPIERETTI ROBERTO
IPC: H02G7/20
Filed: 1997-12-27
Granted: 2003-12-11
Abstract: The present invention relates to a pole head (1) for supporting conductors and the like on poles for medium- and high-voltage overhead power lines, which has the particularity that it comprises at least one tubular portion which has a structural function, is made of electrically insulating composite material, and is fixed to a supporting structure. Coupling flanges (10) for supporting the electrical conductors are connected to the at least one tubular portion and are mutually spaced along the axis of the tubular portion. <IMAGE>
Patent DE-69728010-D1 (DE)
Inventor: DESTEPHEN STEPHEN J
IPC: A23P20/00
Filed: 1997-09-10
Granted: 2004-04-15
Abstract: The present invention relates to a method for increasing the solidification rate of a fat-based confection and to a fat-based confection product wherein the improvement comprises 0.1 to 2.0 % insoluble fiber by weight effective for increasing the rate of solidification of the product. <IMAGE>
Patent DE-69728975-D1 (DE)
Inventor: MARDH SVEN
IPC: A61K39/00
Filed: 1997-02-05
Granted: 2004-06-09
Abstract: The present invention relates to bacteriophages for use in the treatment or prophylaxis of bacterial infections, especially mucosal bacterial infections such as Helicobacter pylori infections. In particular, it relates to modified filamentous bacteriophages, e.g. M13 phages, for such use, which bacteriophages present at its surface a recombinant protein comprising: (i) a first component derived from a bacteriophage surface protein; and (ii) a second component comprising variable region sequences of an antibody to provide a bacterial antigen binding site, said second component rendering said bacteriophage capable of binding to and thereby inhibiting growth of bacterial cells involved in the etiology of said infection.
Patent DE-69735859-D1 (DE)
Inventor: WANG I-FAN
IPC: B01D71/36
Filed: 1997-07-08
Granted: 2006-06-14
Abstract: The present invention relates to cationically charge-modified membranes and methods of preparing such membranes. In one major aspect of the invention, the membranes are hydrophobic membranes that are treated with one or more polymeric wetting agents to render the membranes substantially hydrophilic, followed by treatment with one or more charge-modifying agents, the agents causing the membranes to possess a fixed formal positive charge. In another major aspect of the invention, a cationic membrane is formed from casting in a film a mixed polymer solution comprising a sulfone polymer and a copolymer of vinylpyrrolidone and a cationic imidazolinium compound, and quenching the film in an aqueous bath to produce a coagulated membrane. The membrane can be further cationically charge-modified with one or more charge-modifying agents.
Patent DE-69739187-D1 (DE)
Inventor: PERSSON MATS AXEL ATTERDAG
IPC: C12N1/15
Filed: 1997-04-18
Granted: 2009-02-12
Abstract: The present invention relates to compositions derived from immunoglobulin molecules specific for the hepatitis C virus (HCV). More particularly, the invention is related to molecules which are capable of specifically binding with HCV E2 antigen. The molecules are useful in specific binding assays, affinity purification schemes and pharmaceutical compositions for the prevention and treatment of HCV infection in mammalian subjects. The invention thus relates to novel human monoclonal antibodies specific for HCV E2 antigen, fragments of such monoclonal antibodies, polypeptides having structure and function substantially homologous to antigen-binding sites obtained from such monoclonal antibodies, nucleic acid molecules encoding those polypeptides, and expression vectors comprising the nucleic acid molecules.
Patent DE-69800349-D1 (DE)
Inventor: MARQUE-PUCHEU GERARD
IPC: H04L25/03
Filed: 1998-08-03
Granted: 2000-11-16
Abstract: The accumulated phase filtering of a finite pulse response gives a special time characteristic producing a binary two bit response with three phase increments.
Patent DE-69809541-D1 (DE)
Inventor: BREUKERS JUDITH
IPC: A41D31/00
Filed: 1998-04-03
Granted: 2003-01-02
Abstract: A stab-resisting material includes a carrier coated with solid particles, which is provided on a packet of fabrics, in which the coating on the carrier includes abrasive particles having a diameter of 0.1-3 mm, and in which the packet of fabrics is thicker than 1.5 mm. The abrasive particles may be provided on the carrier by an adhesive, which forms an elastic film after curing. In particular, a fabric made of Aramid or Nylon fibres may be used as the carrier material. The preferred adhesive is a bituminous adhesive or an adhesive with a base of polyurethane. This material is used in particular in protective clothing.
Patent DE-69813773-D1 (DE)
Inventor: BARMORE R
IPC: A23L13/00
Filed: 1998-01-21
Granted: 2003-05-28
Abstract: A multilayer film has a first layer and a second layer. The first layer comprises an additive, a binder, and a crosslinking agent. The additive is a flavor, fragrance, colorant, antimicrobial agent, antioxidant, chelating agent, and/or odor absorbent. The binder is a polysaccharide and/or a protein. The crosslinking agent comprises a compound with at least two carbonyl groups. The second layer comprises a non-water-soluble thermoplastic polymer comprising at least one member selected from the group consisting of polyolefin, polyamide, polyester, polyvinylidene chloride, polyvinyl chloride, and polystyrene. Each of the additive, binder, and crosslinking agent are present throughout a thickness of the first layer. Preferably, the first layer is coated onto the second layer, which is preferably a non-water-soluble thermoplastic polymer, e.g., polyolefin, polyamide, and/or polyester. The film is especially useful for cook-in applications, in which a food product (preferably comprising uncooked meat) is packaged in the film with the coated layer against the meat. The meat is then cooked and the additive transfers to the meat, and purge can be very low. The invention also pertains to a process for preparing a cooked food product, process for making a coated film, and articles formed from the film, such as bags and casings.
Patent DE-69814655-D1 (DE)
Inventor: ROGERS D
IPC: G06F3/0338
Filed: 1998-09-24
Granted: 2003-06-18
Abstract: A pointing device comprises a substrate with an electrically conductive surface (36) and a resilient return member (12). The return member resiliently supports a resistive surface (20) to contact the electrically conductive surface (36) in a pressed mode when a force (23) is applied to push and deform the return member against the electrically conductive surface. The return member (12) is made of a resistive rubber material. The resistive surface (20) has a voltage variance and is curved to be rocked on the electrically conductive surface (36) in the pressed mode. The voltage variance is detected on the electrically conductive (20) surface and a variable signal is generated and processed. In a specific embodiment, a dome switch is disposed between the resistive surface and the electrically conductive surface to provide a drag function.
Patent DE-69815639-D1 (DE)
Inventor: LUNDY DANIEL E
IPC: G03F7/038
Filed: 1998-11-27
Granted: 2003-07-24
Abstract: A negative-acting photoimageable composition useful as a photoresist comprises an acid-functional binder, a photopolymerizable component, a photoinitiator chemical system comprising 9-phenyl acridine or a homologue thereof, and a dibenzoate plasticizer.
Patent DE-69821337-D1 (DE)
Inventor: SCHULTZ K
IPC: C08F2/28
Filed: 1998-01-28
Granted: 2004-03-04
Abstract: An improved method of making CASE materials is provided, wherein the method utilizes a polymer latex derived from at least one ethylenically unsaturated monomer and at least one polymerizable surface active agent. The polymerizable surface active agent is capable of co-polymerization with traditional monomers and is preferably substantially completely consumed during the course of the polymerization. Latex polymers produced by the method of the present invention are well suited for use in coatings, adhesives, sealants, elastomers. Additionally, the present invention relates to improved coating, adhesive, sealant and elastomer (CASE) materials utilizing polymer latexes derived from various monomers and ethylenically unsaturated amine salts of sulfonic, phosphoric and/or carboxylic acids.
Patent DE-69823243-D1 (DE)
Inventor: SIMPSON MICHAEL S
IPC: A22C11/10
Filed: 1998-05-22
Granted: 2004-05-19
Abstract: A meat encasing machine has a looper horn, linking chain and conveyor which, prior to production, have home positions which are determined. A pulsed signal is generated as the looper horn rotates and is transmitted to an amplifier from an encoder on the servo motor for the looper horn and the conveyor. The output pulse signal is then reduced in frequency so that it can be read by a PLC. The PLC counts the pulses in the signal and can determine the relative position of the looper horn based on the count and can therefore minimize the rotation of the looper horn in the home position at the beginning of each new cycle. The meat encasing machine may also be controlled such that the linking chain, looper, and conveyor have no direct mechanical or electrical interaction between each other. By driving the components with separate servo motors, each can be precisely controlled in the desired ratios with respect to each other.
Patent DE-69828717-D1 (DE)
Inventor: HAASEWINKEL GERHARDUS MARTINUS
IPC: B65D43/02
Filed: 1998-04-07
Granted: 2005-03-03
Abstract: The invention relates to a plastic bucket with a bottom and a standing peripheral wall connected thereto, on which peripheral wall an outward extending peripheral flange is present which connects to the peripheral wall at a distance from the mouth rim, which peripheral flange comprises a first flange part extending at least more or less transversely of the peripheral wall and, connecting to the first flange part, a downward extending second flange part with a first free end edge, on which second flange part are formed two handgrips placed mutually diagonally. Each handgrip is embodied as a cowl-like, outward protruding part of the second flange part, comprising a first handgrip part extending outward relative to the second flange part, a downward extending second handgrip part connecting to the first handgrip part and two support shores which are each connected to the second flange part and the peripheral ends of the first handgrip part and the second handgrip part, wherein the lower edge of the second handgrip part lies substantially in the plane of the lower free end edge. <IMAGE>