baber/WOPTO huggingface dataset:
Patent DE-69940820-D1 (DE)
Inventor: SMYTHE MARK LESLIE
IPC: C07K1/04
Filed: 1999-09-24
Granted: 2009-06-10
Abstract: This invention relates to methods for preparing cyclic peptides and peptidomimetic compounds in solution and bound to solid supports, and to cyclic peptide or peptidomimetic libraries for use in drug screening programmes. In particular, the invention relates to a generic strategy for synthesis of cyclic peptides or peptidomimetics that enables the efficient synthesis under mild conditions of a wide variety of desired compounds. Two approaches were evaluated for their improvements in solution and solid phase synthesis of small cyclic peptides: positioning reversible N-amide substituents in the sequence; and applying native ligation chemistry in an intramolecular sense. Systematic investigation of the effects of preorganizing peptides prior to cyclisation by using peptide cyclisation auxiliaries, and developing new linkers and peptide cyclisation auxiliaries to aid cyclic peptide synthesis gives surprising improvements in both yields and purity of products compared to the prior art methods. The combination of these technologies provides a powerful generic approach for the solution and solid phase synthesis of small cyclic peptides. The ring contraction and N-amide substitution technology of the invention provide improved methods for the synthesis of cyclic peptides and peptidomimetics. When used in conjunction with linker strategies, this combination provides solid-phase avenues to cyclic peptides and peptidomimetics.
Patent DE-502004003784-D1 (DE)
Inventor: HAGENMEYER CORD-HERMANN
IPC: B28B7/08
Filed: 2004-07-14
Abstract: The invention relates to a two-pieced tool, comprising a tool lower piece (1), a tool upper piece (3) which is mounted such as to be able to pivot about a pivot axis (5) relative to the tool lower piece (1) and at least one operating cylinder (6, 7, 8, 9), for carrying out the pivoting action of the tool upper piece (3) relative to the tool lower piece (1), in order to open and close the tool. According to the invention, a dead-point position can be avoided, even with a large pivot angle, whereby at least two operating cylinders (6, 7, 8, 9) are connected with the upper connection point thereof (11, 13, 15, 17) to a pivot arm (4) of the tool upper piece (3), eccentric to the pivot axis (5), the lower connection points (10, 12, 14, 16) of which are connected separately to the tool lower piece (1) or a sub-frame (2) housing the tool lower piece .
Patent DE-502004010282-D1 (DE)
Inventor: ROSENAUER MARKUS
IPC: A47C27/08
Filed: 2004-01-12
Abstract: Water bed comprises two adjacent water cores (5, 6) separated by an elastic separating wedge (10) or another elastic flexible separating element and covered preferably by a bed covering (1) on the upper side. The upward-facing longitudinal edge of the separating element is fixed via a connecting element to an adjacent element of the water bed.  Preferred Features: The connecting element between the separating element and the bed covering is a zip fastener or another releasable connecting device. The bed covering consists of two covering strips joined by a zip fastener (4) along the middle line above the separating element. The bed covering is a soft quilted gauze.
Patent DE-502004010471-D1 (DE)
Inventor: INGRISCH STEFAN
IPC: C08K5/3412
Filed: 2004-12-02
Abstract: A description is given of azetidine derivatives and methods for producing them, and of their use as a latent curing component for resins having functional groups which are reactive toward amino groups. The particular advantages of the curing component proposed in accordance with the invention, such as effective producibility, high environmental friendliness, and excellent storage stability of the resin/curing agent mixtures, make these azetidine derivatives outstandingly suitable for one-component, moisture-hardening polymer compositions, which are of special interest in particular for the production of (floor) coatings, sealants, and adhesives.
Patent DE-502005006821-D1 (DE)
Inventor: GRAF HELMUTH
IPC: F16H19/02
Filed: 2005-08-30
Abstract: The device has two drive nuts (4a, 4b) with rotating contact surfaces that are pressable at a shaft (2). The drive nuts exhibit different lead angles, where the contact surfaces are pressed with a larger or smaller lead angles. A coupling device (8) is connected with the drive nuts. The coupling device makes pressing of the contact surfaces of the drive nuts to the shaft, where the contact surface of one drive nut is pressed to the shaft during the rotation of the shaft.
Patent DE-502005010137-D1 (DE)
Inventor: GROEZINGER SVEN OLIVER
IPC: A61N5/10
Filed: 2005-06-09
Abstract: The invention relates to an apparatus and method for compensation of three-dimensional movements of a target volume (1) during ion beam irradiation. For the purpose, the apparatus comprises a position location and tracking system (4) for detecting the movements and a depth modulator (6) for modifying the depth of penetration of the ion beam. For the purpose of compensation, the movements are divided vectorially into a transverse component and a longitudinal component. The transverse component is compensated from irradiation point to irradiation point using the raster scanning apparatus (3) and the longitudinal component is compensated from irradiation point to irradiation point using the depth modulator (6) by means of the fact that, in addition to the change in the location of the target volume, the change in the structure of healthy tissue covering the target volume is, in the preliminaries to irradiation, detected and modelled and stored in the form of a look-up table in a memory of a movement measurement, control and read-out module SAMB and compared with the actual values during irradiation.
Patent DE-502006000039-D1 (DE)
Inventor: BAIERL KLAUS
IPC: B31F1/28
Filed: 2006-05-18
Abstract: The machine has a corrugated medium and a liner assembled by adhesion near corrugation troughs. An ultrasonic transmitter (62) is disposed on one side of a web of corrugated boards. An ultrasonic receiver (63) is disposed on opposite side of the web and allocated to the transmitter. A control and evaluation unit is connected to an ultrasonic receiver for data transmission, in order to evaluate the signal of the ultrasonic receiver.
Patent DE-502006000749-D1 (DE)
Inventor: LIMMERT MICHAEL
IPC: C07D235/20
Filed: 2006-03-21
Abstract: Mixture comprises at least a matrix material and at least a doping material for the production of a layer from a doped organic material, where the doping material is a non-active primary dopant and is obtained from a dimer, oligomer, polymer, dispiro-compound or polycyclic dopant, in which the doping material is cleaved by the impact of activation energy. An independent claim is included for a procedure for forming a doped organic material layer on a substrate by separating (where the doped organic material contains the matrix material and the doped material), comprising transferring the mixture in a steam phase into a common evaporation source and separating the substrate, where the doped material is used as a non-active doped material and the doped material is activated when the procedure is in progress.
Patent DE-502006000827-D1 (DE)
Inventor: NIEHUES STEFAN
IPC: E05C9/18
Filed: 2006-06-26
Abstract: The spring (11) is formed by one or more leaf springs. There are two leaf springs, the second (12) lying on the side of the first spring, which is remote from the head section (10). The spring rests against the end face of the head section, at the end opposite the flange (7). The flange grips behind an edge of a locking strip (5) forming part of the rod-operated catch. The cover rail (2) over the drive rod, includes a slot (6). This has a widening (16) in an open position of the catch, to accept the head section. Elsewhere, this slot is narrower. The leaf springs are aligned to lie along the drive rod. They complete interlocking between the foot (9) and the head section (10) at the mating surfaces (13, 14), and at the upper surface of the cover rail (2). The leaf spring is constructed integrally with a frame surrounding the head section assembly, and closely surrounding the foot. The spring is located in the slot widening (16). It is fastened to the drive rod e.g. by riveting or a catch configuration. It partially surrounds the cover rail.
Patent DE-502006002364-D1 (DE)
Inventor: KRUEGER JOERG DR
IPC: G01K17/20
Filed: 2006-08-22
Abstract: The heat flow sensor consists of at least two contact points (7, 8) arranged respectively on a pipe (3) and spacing bar (4) of the membrane wall (2) made of ferrous material such as low alloyed steel. A respective Constantan wire (10a, 10b) is connected at each point so that the metal of the membrane wall itself forms part of two thermocouples with the wires. The contact points are spaced at a distance appropriate for the measurement of the temperature difference. The thermal conductivity of the individual components, i.e. the pipe, bar and refractory lining (11), the heat transfer from the pipe into the boiling water (13), and the specific heat flux on the membrane wall are all taken into account in presenting the measured differential voltages as heat flow units on the display device (9). An independent claim is included for a method for designing and testing of the heat transfer performance in wall regions of thermal power plants.
Patent DE-502006002403-D1 (DE)
Inventor: HABIG BERND
IPC: B65D5/50
Filed: 2006-02-14
Abstract: A carton container for general house removal goods is rectangular and has a base and four sidewalls. Two opposite sidewalls are short with hand hold apertures, and two sides are long. The container is assembled from a blank that is stored flat. The side edges (L1) of the first (6, 8) and second (7, 9) base edges are shorter than the length (L2) of the upper and base edges of the end walls (3, 4) and have overlapping locking elements.
Patent DE-502006006154-D1 (DE)
Inventor: BAUDER RALF
IPC: B01D29/21
Filed: 2006-09-13
Abstract: A filter comprises two concentrically arranged, cylindrical fluted elements (12a, b) mounted between endplates (11a, b), to form an annular feed ring (25) fed by radial distribution channels (22) within the upper end plate (11a) from feed inlet port (17, 18) via a plenum (21). Clean fluid emerges both inwardly and outwardly from (12a, b) via the perforated supporting centre tube (13, 15) and outer wall (14). An independent claim is included for use of the filter element for cleaning the dielectric fluid for a spark erosion milling machine. The components of the upper end plate may be injection moulded separately in thermoplastics and glued or welded together, or integrally formed by a gas pressurized moulding process (GID).
Patent DE-502007002688-D1 (DE)
Inventor: RAFELD-CECH KARIN
IPC: E06B3/667
Filed: 2007-10-07
Abstract: The connector (1) comprises a shell-type pin (10) in a middle area of longitudinal extension of the connector, where the pin points a direction of an open side of a U-profile. The height of the pin in a boundary lying transverse to the longitudinal direction of the connector is larger than in a middle region. A stopper (6) is arranged in a region of center of the extension of the connector. A resilient adjusting element (7) is provided in a region of the stopper. A floor space (2) comprises a through hole (8), where the connector is made of plastic.
Patent DE-502008000168-D1 (DE)
Inventor: REINERT KARL-ALBERT
IPC: F16L23/16
Filed: 2008-01-16
Abstract: Flange connection (10) comprises an equalizing ring (30) arranged between annular bands (15) of a pipe piece (11) and an axial seal (16). The equalizing ring and the pipe piece fit into each other using a peripheral tongue-and-groove connection (31). The tube piece and the ring form a cylindrical surface pair (35). An O-ring (36) is arranged in the region of the surface pair. Preferred Features: The radial seal is assigned to the outermost part of the surface pair. The equalizing ring is fastened to the annular band of the pipe piece.
Patent DE-502008001160-D1 (DE)
Inventor: STEINER JOHANN
IPC: F24D19/10
Filed: 2008-01-17
Abstract: The invention relates to a device for regulating the temperature of industrial water (19), which is heated in a heat exchanger by means of a heating medium (18), having an industrial water valve (13a, 13b) controlling the flow rate of the industrial water (19) to the heat exchanger, and a heating medium valve (12a, 12b) controlling the flow rate of the heating medium (18) from the heat exchanger, wherein the industrial water valve (13a, 13b) comprises an industrial water valve seat (13b) and an industrial water valve closure part (13a) that can be displaced relative thereto. The heating medium valve (12a,12b) comprises a heating medium valve seat (12b) and a heating medium valve closure part (12a) that can be displaced relative thereto. The industrial water valve (13a,13b) and the heating medium valve (12a,12b) are in operative connection to each other by means of a tapered rod (11), wherein a generally known pressure-controlled controller (1) is provided, which acts on the tapered rod (11) as a function of the removal of industrial water (19), and wherein further a generally known thermostatically controlled controller (4) is provided, which acts exclusively on the heating medium valve (12a, 12b) as a function of the temperature of the industrial water (19).
Patent DE-502008002460-D1 (DE)
Inventor: DITTMER LOTHAR
IPC: D06F58/04
Filed: 2008-11-26
Abstract: The shield (1) has a drum sealing groove (2) for accommodating a front drum seal (6). A groove base (5) of the drum sealing groove has continuous tapered toothing (3) in sections. The toothing is formed against a rotational direction of a washing drum (7), and perpendicularly extending ribs (4) are formed in a side wall of the groove and are formed in wedge-shape. The drum seal is made of foam or combination of foam and felt, and the shield is made of plastic.
Patent DE-602004001386-D1 (DE)
Inventor: CHEN SHUN-MIN
IPC: A47D7/00
Filed: 2004-04-19
Abstract: A baby crib includes a bed frame structure 1, a fabric member 2 mounted on the bed frame structure 1 to define a surrounding wall around the bed frame structure 1, and a plurality of positioning posts 22 mounted on the fabric member 2. The bed frame structure 1 includes a plurality of upright tubes 11, each of which has a tube wall 110 defining a receiving hole 111 and having a slit 112 that extends along the length of the tube wall 110 and that is in spatial communication with the receiving hole 111. The positioning posts 22 are inserted respectively into the receiving holes 111 in the upright tubes 11. The fabric member 2 is clamped between each upright tube 11 and a corresponding positioning post 22, and extends outward through the slit 112 in each upright tube 11. <IMAGE>
Patent DE-602004003697-D1 (DE)
Inventor: DE VRIES HINDRIK WILLEM
IPC: H01J37/32
Filed: 2004-08-13
Abstract: The present invention is directed to a method and arrangement for controlling a glow discharge plasma in a gas or gas mixture under atmospheric conditions, in a plasma discharge space comprising at least two spaced electrodes (2), wherein at least one plasma pulse having an absolute pulse maximum is generated by applying an AC plasma energizing voltage to the electrodes (2) causing a plasma current and a displacement current. The plasma is controlled by providing a relative decrease of the displacement current after the pulse maximum. In a preferred embodiment, the energizing voltage is applied through a series circuit of a choke coil (3) and a non-saturable inductor (4).
Patent DE-602004007001-D1 (DE)
Inventor: PERCIVALLE DOMENICO
IPC: B41F31/02
Filed: 2004-07-23
Abstract: An inking and doctor unit for a rotogravure print and spread cylinder includes a casing; a doctor assembly; and an inking chamber bounded by a concave inner surface of the casing and at least partly by the doctor assembly. The casing and the doctor assembly form a box body closed except for one side engaging a print cylinder having a first axis; and the doctor assembly has a doctor mounted to lie flat with respect to a lateral surface of the print cylinder, when the box body engages the print cylinder.
Patent DE-602004008357-D1 (DE)
Inventor: DE GOUY JEAN-LUC
IPC: H03K23/00
Filed: 2004-02-06
Abstract: The divider divides a frequency by adapting an input for a frequency signal to be divided, where the input is provided for a control (NA) of the base level of division, and for a control (delta NA) of a division chain, and varying the NA. The chain has a division step, where a switch controlled by a divider by 2 has an input for programming data, a hold signal input for following step and a hold signal output for preceding step.
Patent DE-602004008714-D1 (DE)
Inventor: PAUMIER CARINE
IPC: B60H3/00
Filed: 2004-08-16
Abstract: The installation has an electrostatic filtration system (30) for treating particles, and a plasma catalysis system (40) for treating gas pollutants, odors and micro-organisms. The system (30) has an ionizer for ionizing particles before they are collected by a particle filter. The system (30) is placed upstream of the system (40) in a manner to limit choking of the system (40).
Patent DE-602004014289-D1 (DE)
Inventor: HOLMES BRIAN WILLIAM
IPC: B42D15/00
Filed: 2004-11-03
Abstract: A security device comprises a holographic or diffractive optically variable effect generating structure which, when viewed normally i.e. perpendicularly to the plane of the device, replays at least one composite image, the composite image being defined by at least a pair of discrete image elements, the structure being such that at least two of the discrete image elements of the composite image have different optimal replay angles.
Patent DE-602004014448-D1 (DE)
Inventor: SING BING KANG
IPC: G06T1/00
Filed: 2004-06-15
Abstract: A system and process for generating a high dynamic range (HDR) image from a bracketed image sequence, even in the presence of scene or camera motion, is presented. This is accomplished by first selecting one of the images as a reference image. Then, each non-reference image is registered with another one of the images, including the reference image, which exhibits an exposure that is both closer to that of the reference image than the image under consideration and closest among the other images to the exposure of the image under consideration, to generate a flow field. The flow fields generated for the non-reference images not already registered with the reference image are concatenated to register each of them with the reference image. Each non-reference image is then warped using its associated flow field. The reference image and the warped images are combined to create a radiance map representing the HDR image. <IMAGE>
Patent DE-602004023659-D1 (DE)
Inventor: GABERT JEAN
IPC: C12Q1/68
Filed: 2004-03-08
Abstract: The application relates to sets of nucleic acid probes and primers and their use in a method for detection of minimal residual disease in leukemic patients, in which at least one PML-RARA fusion gene transcript variant is amplified and detected.
Patent DE-602004025373-D1 (DE)
Inventor: KAERN VIGGO AABERG
IPC: A61M39/24
Filed: 2004-11-19
Abstract: A body fluids drainage system includes a urinary catheter, a drainage collection bag, and a connection member connected between the urinary catheter and the drainage collection bag. The connection member houses a valve element formed from a sheet of material and projecting a coherent plane. The valve element defines a longitudinal direction extending between a connecting portion and a flap portion and a recess formed on a periphery of the valve element between the connecting portion and the flap portion.
Patent DE-602004025832-D1 (DE)
Inventor: VAYSSIERE JULIEN
IPC: G06F9/54
Filed: 2004-12-20
Abstract: A distributed computer system in several embodiments includes several architectures or configurations. Each configuration exhibits a different degree of coupling between an application that provides data and an application that consumes that data. In an embodiment, a provider application knows the identity of a consumer application, converts data into the format of the consumer application, and transmits the data to the consumer application. In other embodiments, the provider application does not know the identity of the consumer application, and transmits data to the consumer application through an intermediary. In such embodiments, either the provider or the intermediary can perform the data conversion. In another embodiment, a manager object oversees the transformation of the system from one configuration to another in real time. The transformation is achieved by migrating objects from one object space to another.
Patent DE-602004027725-D1 (DE)
Inventor: HALL CHARLES E
IPC: B65D47/08
Filed: 2004-02-09
Abstract: A universal box top lid is adapted to be attached to the opened top of a variety of different sizes of food packaging boxes. The lid is designed to fit over the opened box top with an opened bag containing the food product inside the box being held open by an apron formed on an inner wall of the lid. The lid is provided with a cap closure that can be opened when it is desired to dispense the food product contained in the packaging box and bag, and can be closed to preserve the food product.
Patent DE-602004029197-D1 (DE)
Inventor: FRANTZ DIDIER
IPC: G06K7/14
Filed: 2004-04-28
Abstract: This present invention discloses a system and method for enhancing images of barcodes and other similar objects taken by the digital camera connected to or embedded in a mobile device. This filter works by converting the image into its equivalent gray scale. The algorithm then divides the image into sections and finds the pixels of minimum intensity in each section of the image. This minima is used to calculate cut-off values for thresholding. After thresholding, the image is reassembled from its divided sections.
Patent DE-602004030084-D1 (DE)
Inventor: FUJIKURA TETSUYA
IPC: A61B1/00
Filed: 2004-12-03
Abstract: An over tube 50 is formed by a tube body 51, and a gripping part 52 in which a liquid storing part 53 is formed. A connecting port 52A formed at a tip end of the gripping part 52 is fitted into a base end opening 51A of the tube body 51 in a watertight state, so that the gripping part 52 is constructed attachably and detachably with respect to the tube body 51. The liquid storing part 53 is formed into a spherical shape with a larger diameter than a diameter of the tube body 51, and an arc-shaped recessed portion 80 is formed in an inside of the liquid storing part 53. A sponge 82 formed into a donut shape is housed in this recessed portion 80. During an operation, a body fluid flowing backward from a gap between the tube body and an insertion section 12 is stored in the recessed portion 80 and is absorbed in the sponge 82, thus preventing liquid leakage from the recessed portion 80.
Patent DE-602004031681-D1 (DE)
Inventor: PAUL STEPHANE
IPC: C12N15/861
Filed: 2004-07-20
Abstract: The present invention relates to a novel fusion protein with the formula X-Y, or Y-X, wherein X represents a first immulloregulating polypeptide and Y represents a second immunoregulating polypeptide different from X. The present invention also relates to a nucleic acid molecule encoding such a fusion protein and a vector comprising such a nucleic acid molecule. The present invention also provides infectious viral particles and host cells comprising such a nucleic acid molecule or such a vector as well as a process for producing such infectious viral particles. The present invention also relates to a method for recombinantly producing such a fusion protein. Finally, the present invention also provides a pharmaceutical composition comprising such a fusion protein, a nucleic acid molecule, a vector, infectious viral particles and a host cell as well as the therapeutic use thereof.