baber/WOPTO huggingface dataset:
Patent AU-2019206534-A1 (AU)
Title: Compact injector systems and methods
Inventor: WALLER LINDA J
IPC: A61M5/46
Filed: 2019-01-10
Abstract: Devices and methods for a compact injector are provided with a compact configuration for ease of carrying or storage, and an activated configuration ready for injection. In the compact configuration, a plunger and a needle are both retracted into the injector housing, and upon actuation to the activated configuration, the plunger extends proximally and the needle extends distally, ready for injection. An extendable needle shield is also provided to block visibility of the needle during injection, and to reduce the risk of inadvertent needle stick at other times, including disposal.
Patent AU-2019215196-A1 (AU)
Title: Compositions and methods for treatment of obesity and obesity-related disorders
Inventor: MANSELL JOHN
IPC: B82Y5/00
Filed: 2019-02-01
Abstract: A method of inhibiting the expression of ghrelin in a cell, method comprising introducing to the cell an RNAi, the RNAi comprising a sense strand and an antisense strand, the antisense strand comprising any of SEQ ID NO: 1 to SEQ ID NO: 42, and the sense strand being complementary to the antisense strand. Also, a method of inhibiting the expression of ghrelin o-acyltransferase in a cell, the method comprising introducing to the cell an RNAi, the RNAi comprising a sense strand and an antisense strand, the antisense strand comprising any of SEQ ID NO: 43 to SEQ ID NO: 68, and the sense strand being complementary to the antisense strand.
Patent AU-2019231232-A1 (AU)
Title: Three dimensionally shaped biofabricated materials and methods of manufacture
Inventor: BABIN NICHOLAS JOHN
IPC: A61L27/38
Filed: 2019-03-05
Abstract: Described herein are three dimensionally shaped biofabricated materials and method of making three dimensionally shaped biofabricated materials.
Patent AU-2019240567-A1 (AU)
Title: Methods, systems, and devices for detecting and identifying microorganisms in microbiological culture samples
Inventor: WEIDEMAIER KRISTIN
IPC: G01N33/569
Filed: 2019-09-30
Abstract: Provided herein are methods, systems, and devices for detecting and/or identifying one or more specific microorganisms in a culture sample. Indicator particles, such as surface enhanced Raman spectroscopy (SERS)-active nanoparticles, 5 each having associated therewith one or more specific binding members having an affinity for the one or more microorganisms of interest, can form a complex with specific microorganisms in the culture sample. Further, agitating magnetic capture particles also having associated therewith one or more specific binding members having an affinity for the one or more microorganisms of interest can be used to capture 10 the microorganism-indicator particle complex and concentrate the complex in a localized area of an assay vessel for subsequent detection and identification. The complex can be dispersed, pelleted, and redispersed so that the culture sample can be retested a number of times during incubation so as to allow for real-time monitoring of the culture sample. . 7,4 0.o w cc
Patent AU-2019250242-A1 (AU)
Title: Extracellular matrix composition beads for cell culture
Inventor: HARIRI ROBERT J
IPC: C12N5/02
Filed: 2019-10-18
Abstract: Abstract Provided herein are methods of culturing cells using microcarriers that include extracellular matrix (ECM).
Patent AU-2019275314-A1 (AU)
Title: Dynamic hyperpolarized 129Xe GAS EXCHANGE SPECTROSCOPY
Inventor: BIER ELIANNA
IPC: A61B5/055
Filed: 2019-05-10
Abstract: Methods and systems with
Patent AU-2019300135-A1 (AU)
Title: Combinations of PPAR agonists and p38 kinase inhibitors for preventing or treating fibrotic diseases
Inventor: BAUSCH ALEXANDER
IPC: A61K31/519
Filed: 2019-07-05
Abstract: The present invention relates to a pharmaceutical combination comprising: (a) a PPAR agonist; (b) a p38 kinase inhibitor; and optionally (c) one or more pharmaceutically acceptable diluents, excipients or carriers for use in a method of preventing or treating fibrotic diseases or disorders in a subject.
Patent AU-2019316855-A1 (AU)
Title: Transmission method and device for uplink control information and computer storage medium
Inventor: ZHANG YI
IPC: H04W72/04
Filed: 2019-08-06
Abstract: Disclosed are a transmission method and device for uplink control information and a computer storage medium. The method comprises: a terminal, according to the type of physical uplink shared channel (PUSCH) and/or the type of uplink control information, selecting a corresponding first PUSCH configuration parameter, and the terminal transmitting the uplink control information on the basis of the first PUSCH configuration parameter, wherein different PUSCH configuration parameters correspond to PUSCH of different types and/or uplink control information of different types.
Patent AU-2019319458-A1 (AU)
Title: Adjustable refrigerator drawer assembly
Inventor: WEI DONG
IPC: F25D25/02
Filed: 2019-08-02
Abstract: An adjustable refrigerator drawer assembly (100), comprising a drawer body (10) having a cavity for placing articles; a sliding assembly (20), slidably disposed in the drawer body (10) in a direction perpendicular to the drawing direction of the drawer body (10); and at least one partition plate (30) detachably connected to the sliding assembly (20) and configured to partition an accommodating cavity and move along with the sliding assembly (20) to change the sizes of chambers partitioned by the partition plate (30). The adjustable refrigerator drawer assembly (100) can effectively use the space of the drawer body to simplify the disassembling and assembling process of the partition plate (30).
Patent AU-2019335025-A1 (AU)
Title: Methods and compositions for retinal neuron generation in carrier-free 3D sphere suspension culture
Inventor: QIANG FENG
IPC: C12N5/0789
Filed: 2019-09-06
Abstract: Provided herein, in one aspect, is a population of retinal neurons including photoreceptors precursor cells (PRPCs) generated
Patent AU-2019339464-A1 (AU)
Title: Methods for mass spectrometry analysis of engineered cell compositions
Inventor: PRENTICE KENNETH MAYO
IPC: G01N33/569
Filed: 2019-09-11
Abstract: Provided herein are methods for generating a mass spectrometry (MS) profile of a sample from a cell composition, such as an engineered cell composition. In some embodiments, the mass spectrometry profile includes data based on one or more mass spectrometry analyses or techniques. Also provided herein are methods for, based on mass spectrometry profiles of one or more samples of such cell compositions: identifying a mass spectrometry (MS) profile of a genetically engineered cell composition comprising immune cells comprising a recombinant receptor by comparison to a reference mass spectrometry profile; characterizing a process for producing genetically engineered cell composition; assessing cell surface proteins of an engineered cell composition; and assessing a process for producing a genetically engineered cell composition.
Patent AU-2019349607-A1 (AU)
Title: Medical device and method for performing a surgical operation in a body
Inventor: POULETTY PHILIPPE
IPC: A61B34/00
Filed: 2019-09-24
Abstract: The present invention relates to a medical device (10), preferably a micro robot for application inside a body, preferably for application inside a human body (2). The medical device (10) includes a body part (11) and a tail part (12). A recapture line (13) is attached to the tail part (12). The recapture line (13) has a tensile strength sufficient to pull back the device and column strength not sufficient to push the medical device (10).
Patent AU-2019357130-A1 (AU)
Title: Variable phase and frequency pulse-width modulation technique
Inventor: LONG BENJAMIN JOHN OLIVER
IPC: H03K11/00
Filed: 2019-10-14
Abstract: Phased array systems rely on the production of an exact carrier frequency to function. Reconstructing digital signals by specified amplitude and phase is accomplished explicitly by inducing frequency shifts away from a base frequency implied by phase changes. Shifting the carrier frequency of a digitally controlled phased array while preserving the timing of the individual phase pulses enables more efficient driving of the phased array system when the phase of the drive signals change dynamically in time.
Patent AU-2019361322-A1 (AU)
Title: Hair rejuvenation
Inventor: KEMP PAUL
IPC: A61K35/36
Filed: 2019-10-17
Abstract: The invention in relates in part to a method for rejuvenating hair follicles, the method comprising the steps of: (1) obtaining androgen non-inhibited cells from hair follicle tissue; (2) culturing the androgen non-inhibited cells to produce an expanded population of androgen-non-inhibited cells; and (3) implanting the expanded population of androgen non-inhibited cells proximal to miniaturised and/or miniaturising hair follicles.
Patent AU-2019383845-A1 (AU)
Title: Novel tricyclic compound as IRAK4 inhibitor
Inventor: CHO HEEYEONG
IPC: A61P35/00
Filed: 2019-11-20
Abstract: The present invention relates to a pharmaceutical composition for preventing or treating autoimmune diseases or tumors, containing, as an active ingredient, a tricyclic compound represented by the following formula 1 or a pharmaceutically acceptable salt thereof, and a health food composition for preventing or alleviating autoimmune diseases or tumors, containing the tricyclic compound as an active ingredient. [Chemical formula 1] A tricyclic compound represented by chemical formula 1 of the present invention has an excellent inhibitory activity against IRAK4, and thus can be effectively used in the prevention, treatment, or alleviation of autoimmune diseases or tumors.
Patent AU-2019396527-A1 (AU)
Title: Techniques for patient-specific morphing of virtual boundaries
Inventor: BECKER HANS-ULRICH
IPC: A61B34/20
Filed: 2019-12-12
Abstract: Systems, methods, software and techniques are disclosed for morphing a generic virtual boundary into a patient-specific virtual boundary for an anatomical model. The generic virtual boundary comprises one or more morphable faces. An intersection of the generic virtual boundary and the anatomical model is computed to define a cross-sectional contour of the anatomical model. One or more faces of the generic virtual boundary are morphed to conform to the cross-sectional contour of the anatomical model to produce the patient-specific virtual boundary. In some cases, the morphed faces are spaced apart from the cross-sectional contour by an offset distance that accounts for a geometric feature of a surgical tool.
Patent AU-2019424375-A1 (AU)
Title: N-heterocyclic five-membered ring-containing capsid protein assembly inhibitor, pharmaceutical composition and uses thereof
Inventor: ZHANG YINSHENG
IPC: A61P31/20
Filed: 2019-09-27
Abstract: Provided is a compound of formula I or II, a stereoisomer, a tautomer, a geometrical isomer, a solvate, an active metabolite, a hydrate, a prodrug or a pharmaceutically acceptable salt thereof, a pharmaceutical composition thereof, and the medical uses thereof in treating diseases benefiting from the capsid protein assembly inhibitor, particularly diseases caused by hepatitis B virus infection.
Patent AU-2019452577-A1 (AU)
Title: Cell-binding molecule-Tubulysin derivative conjugate and preparation method therefor
Inventor: ZHAO ROBERT
IPC: A61P35/00
Filed: 2019-06-29
Abstract: Involved is the conjugation of a Tubulysin derivative (homolog) to a cell-binding molecule by using branched (side-chain) linkers, wherein the resulting conjugate has better pharmacokinetic properties, and thus can more accurately target and kill abnormal cells. Also involved are the conjugation of the Tubulysin homolog to a cell-binding agent, a method for synthesizing molecules contained therein, and a method for treating cancers, infections and autoimmune diseases in a targeted manner by using the conjugate. The Tubulysin conjugate with long branched linkers has an increased half-life during targeted delivery and has minimal exposure to non-target cells, tissues or organs during blood circulation, resulting in a reduced off-target toxicity.
Patent AU-2020200726-A1 (AU)
Title: Use of short term starvation regimen in combination with kinase inhibitors to enhance traditional chemo-drug efficacy and feasibility and reverse side effects of kinases in normal cells and tissues
Inventor: LONGO VALTER D
IPC: A61K31/4745
Filed: 2020-01-31
Abstract: A method of alleviating or treating symptoms of cancer and/or effects of chemotherapy or of kinase inhibitors includes a step of identifying a subject having cancer. A reduced caloric diet is administered to the subject for a first time period, the reduced caloric diet providing at most 1000 kcal per day. A kinase inhibitor is administered to the subject.
Patent AU-2020202712-A1 (AU)
Title: Treatment of cancer with dual targeting of CD47 and EGFR
Inventor: WEISSMAN IRVING L
IPC: A61P35/00
Filed: 2020-04-23
Abstract: Methods are provided for targeting cells for depletion, including without limitation cancer cells, in a regimen comprising contacting the targeted cells with a combination of agents, including (i) an agent that blockades CD47 activity; and (ii) an antibody that specifically binds to EGFR. In some embodiments the cancer cells have a mutated form of one or more of KRAS, NRAS or BRAF. The level of depletion of the targeted cell is enhanced relative to a regimen in which a single agent is used; and the effect may be synergistic relative to a regimen in which a single agent is used.
Patent AU-2020203323-A1 (AU)
Title: Dropout recloser
Inventor: MONTENEGRO ALEJANDRO
IPC: H01H75/04
Filed: 2020-05-21
Abstract: A dropout recloser is capable of in accordance with its operating programming after a predetermined number of fault interrupting operations, e.g., 1, 2, 3 or more but typically 3, to drop out of a cutout and hang freely in a hinge contact of the cutout providing sectionalization with an observable visible gap. The recloser includes fault interrupting and reclosing components, a drop out mechanism and a controller. The drop out mechanism may include a bi-stable actuator to affect fault interrupting operation and dropout operation. The device may include motion limiting structures. The recloser may have a number of operating modes or sequences.
Patent AU-2020203590-A1 (AU)
Title: Mirna biogenesis in exosomes for diagnosis and therapy
Inventor: KALLURI RAGHU
IPC: G16B20/00
Filed: 2020-06-01
Abstract: Methods for diagnosis and treatment of cancers by use of exosomes comprsing miRNAs and precursors thereof. For example, in some aspects, a cancer may be diagnosed or evaluated by determining the miRNA content of exosomes in a sample from a subject or by detecting miRNA processing in exosomes.
Patent AU-2020208143-A1 (AU)
Title: Reduced dead space catheter adapter
Inventor: NAIDU JITHENDRA KUMAR SATHYANARAYANA
IPC: A61M25/00
Filed: 2020-01-06
Abstract: A catheter assembly may include a catheter adapter, which may include a distal end, a proximal end, a lumen extending between the distal end and the proximal end, and a side port. A septum may be disposed within the lumen of the catheter assembly. The side port may include a lumen in fluid communication with the lumen of the catheter adapter. The lumen of the side port may be distally-facing, which may facilitate flushing of fluid trapped proximate a distal face of the septum. The catheter assembly may include a catheter secured within the catheter adapter and extending distally from the catheter adapter.
Patent AU-2020225594-A1 (AU)
Title: Powdery mildew resistant cannabis plants
Inventor: SHERMAN TAL
IPC: A01H6/28
Filed: 2020-02-20
Abstract: The present invention discloses a modified Cannabis plant exhibiting enhanced resistance to powdery mildew (PM). The aforementioned modified Cannabis plant comprises a targeted genome modification conferring reduced expression of at least one Cannabis MLO (CsMLO) allele as compared to a Cannabis plant lacking said targeted genome modification. The present invention further discloses methods for production of the modified Cannabis plant using genome modification.
Patent AU-2020226295-A1 (AU)
Title: Belt contact surface with inserts, and a conveyor system using same
Inventor: STEPHENSON ROBERT ROY
IPC: B60S3/00
Filed: 2020-02-20
Abstract: A conveyor system is provided, including an endless belt and a support deck. The endless belt is mounted in a longitudinal direction through a service line, the endless belt having an upper transport portion adapted to move a wheeled structure through the service line, and a lower return portion. The support deck is positioned below the upper transport portion of the endless belt to support the endless belt. The support deck has a belt contact surface extending along a top of the support deck and in contact with the upper transport portion of the endless belt. The belt contact surface is at least partially constructed from a material that is at least partially a polymer, and has a set of inserts having a greater abrasion resistance than the material.
Patent AU-2020244558-A1 (AU)
Title: Devices and methods for delivering a lyophilized medicament
Inventor: EDWARDS EVAN T
IPC: A61M5/178
Filed: 2020-10-01
Abstract: An apparatus includes a housing, an actuator, a lock mechanism, and a medicament 
container. The lock mechanism selectively engages a portion of the housing such that (1) the 
lock mechanism is maintained in a substantially fixed position when the housing is in a first 
orientation and (2) the lock mechanism is removable from the housing when the housing is in 
a second orientation. The medicament container is moved in a proximal direction when the 
lock mechanism is removed from the housing to mix a first medicament portion contained 
within the medicament container with a second medicament portion contained within the 
medicament container. The actuator can be moved from a first position to a second position 
when the lock mechanism is removed from the housing to release energy stored within an 
energy storage member such that the medicament container is moved in a distal direction.
Patent AU-2020258264-A1 (AU)
Title: Dynamically rigidizing composite medical structures
Inventor: TILSON ALEXANDER Q
IPC: A61M25/02
Filed: 2020-01-16
Abstract: A rigidizing device includes a plurality of layers and an inlet between the elongate flexible tube and the outer layer and configured to attach to a source of vacuum or pressure. The rigidizing device is configured to have a rigid configuration when vacuum or pressure is applied through the inlet and a flexible configuration when vacuum or pressure is not applied through the inlet.
Patent AU-2020263787-A1 (AU)
Title: Persistent flux biasing methodology for superconducting loops
Inventor: SANDBERG MARTIN
IPC: G06N10/00
Filed: 2020-03-27
Abstract: A tunable qubit device includes a tunable qubit, the tunable qubit including a superconducting quantum interference device (SQUID) loop. The tunable qubit device further includes a superconducting loop inductively coupled to the SQUID loop, and a flux bias line inductively coupled to the superconducting loop. The superconducting loop includes a superconducting material having a critical temperature that is a lower temperature than a critical temperature of any superconducting material of the tunable qubit. In operation, the superconducting loop provides a persistent bias to the tunable qubit.
Patent AU-2020319189-A1 (AU)
Title: Production of high purity organic lactic acid and its salts and various applications thereof
Inventor: KUCHIMANCHI VENKATA SATYA SARVESWARA SAIRAM
IPC: C12P7/56
Filed: 2020-06-10
Abstract: The present invention relates to a novel, time and cost effective, commercially viable and environmentally safe fermentative production process for "High Purity Organic Lactic acid and its Salts and Various Applications in livestock, food and pharma industry as well as acidifier in aqua culture". A microbial consortium of
Patent AU-2020343931-A1 (AU)
Title: Pregelatinized pea starch for batter and coating
Inventor: PERERA CHANDANI
IPC: A23L13/50
Filed: 2020-09-04
Abstract: The present disclosure includes methods and compositions using pregelatinized pea starch in fried batter coatings to provide viscosity, to prevent sedimentation by eliminating the need for other hydrocolloids such as xanthan or guar gum, and to improve crispness in fried foods.
Patent AU-2020350529-A1 (AU)
Title: Cyano-substituted cyclic hydrazine derivative and application thereof
Inventor: SHEN WANG
IPC: A61P37/06
Filed: 2020-06-11
Abstract: The present invention provides a cyano-substituted cyclic hydrazine derivative, comprising: a compound represented by the following structural formula or a stereoisomer, a geometric isomer, a tautomer, a racemate, a hydrate, a solvate, a metabolite, and a pharmaceutically acceptable salt or a prodrug thereof. The compound is used for prevention, treatment or alleviation of autoimmune diseases or proliferative diseases in patients, and/or for inhibiting or modulating protein kinase activity.
Patent AU-2020360716-A1 (AU)
Title: Peptide compounds for reducing side effects of CB1 receptor agonists
Inventor: CASADÓ BURILLO VICENT
IPC: A61P25/00
Filed: 2020-10-02
Abstract: The present invention relates to compounds of formula (I): AA
Patent AU-2020375557-A1 (AU)
Title: Field effect transistor having field plate
Inventor: DAVIS MICHAEL S
IPC: H01L21/338
Filed: 2020-08-28
Abstract: A field effect transistor having a field plate structure for shaping an electric field in a region between the gate (22) and the drain (20), such field plate structure having: a dielectric layer (24) disposed on the gate and on the surface of the semiconductor in the region between the gate and the drain; and electric charge (41) disposed in portions of the dielectric layer, a portion of such charge being disposed in the dielectric layer over an upper surface of the gate and another portion of the change extending from the upper surface of the gate into the region between gate and the drain; and wherein the electric charge solely produces the electric field.
Patent AU-2020378330-A1 (AU)
Title: Diagnostic and therapeutic methods for treatment of hematologic cancers
Inventor: HUANG HUANG
IPC: C07K16/28
Filed: 2020-11-05
Abstract: Disclosed herein are diagnostic and therapeutic methods for the treatment of hematologic cancers, including multiple myeloma (MM), as well as related compositions. In particular, the invention relates to diagnostic and therapeutic methods for treatments involving a PD-L1 axis binding antagonist (e.g., an anti-PD-L1 antibody, e.g., atezolizumab) and an anti-CD38 antibody (e.g., an anti-CD38 antagonist antibody, e.g., daratumumab) for use in treating hematologic cancer (e.g., a multiple myeloma (MM), e.g., a relapsed or refractory MM).
Patent AU-2020380380-A1 (AU)
Title: Methods of reducing virus molecule levels
Inventor: KAO CHIA-CHENG
IPC: C12N15/113
Filed: 2020-11-06
Abstract: The present application is directed to reducing virus levels and treating virus infection in a subject. This treatment achieved by targeting cellular host factors in the subject, these being GRP78/BIP, SRSF1, HNRNP A2B 1, RPLP1 and RPLP2. This targeting is achieved using oligonucleotide inhibitors, particularly siRNAs. Viral infections to be treated include Hepatitis B and respiratory viruses such as coronavirus SARS-CoV2. Isolated oligonucleotide inhibitors targeting RNA, and pharmaceutical compositions comprising these oligonucleotides is also anticipated.