baber/WOPTO huggingface dataset:
Patent IL-70241-A0 (IL)
Title: New esters derived from 2,2-dimethylcyclopropane carboxylic acids and biaryl alcohols,their preparation process,their use in combatting parasites and the compositions containing them
IPC: A23K1/16
Filed: 1983-11-15
Abstract: Novel esters in all possible isomeric forms or a mixture thereof having the formula    <IMAGE>  I  wherein Y is selected from the group consisting of hydrogen, halogen, -OAlK and   <IMAGE>  AlK is alkyl of 1 to 6 carbon atoms, n is 0, 1 or 2, Z is selected from the group consisting of -O- and -S-, R1 is selected from the group consisting of (a) optionally unsaturated alkyl of 1 to 8 carbon atoms and optionally unsaturated cycloalkyl or cycloalkylalkyl of 3 to 8 carbon atoms optionally substituted with at least one member of the group consisting of halogen, -OH, -SH, -OR', -SR',   <IMAGE>  +TR <IMAGE>    -SO2AlK2, -SO3AlK3, aryl optionally substtuted with at least one member of the group consisting of -OH, alkoxy of 1 to 8 carbon atoms, alkyl of 1 to 8 carbon atoms, halogen, -CF3, -OCF3, -SCF3 and   <IMAGE>  R' is alkyl of 1 to 8 carbon atoms, R'' and R''' are individually selected from the group consisting of hydrogen and alkyl of 1 to 8 carbon atoms, AlK1, AlK2 and AlK3 are individually alkyl of 1 to 18 carbon atoms (b) aryl of 6 to 14 carbon atoms optionally substituted with at least one substituent selected from the group consisting of -OH, alkoxy of 1 to 8 carbon atoms, alkyl of 1 to 8 carbon atoms, halogen, -OCF3, -CF3 and -SCF3 and (c) heterocycle optionally substituted with at least one member of the group consisting of -OH, alkoxy of 1 to 8 carbon atoms, alkyl of 1 to 8 carbon atoms, halogen, -CF3, -OCF3 and -SCF3, R2, R3 and R4 are individually selected from the group consisting of hydrogen, halogen, alkyl of 1 to 8 carbon atoms, haloalkyl of 1 to 8 carbon atoms containing a plurality of halogens and alkoxy of 1 to 8 carbon atoms, W is selected from the group consisting of hydrogen and -CN, X is selected from the group consisting of carbon and nitrogen, Ar is selected from the group consisting of optionally substituted phenyl, pyridyl, thienyl, naphthyl, furyl and pyrrolyl and the ethylenic double bond may have Z or E geometry having parasitic activity, especially insecticidal, acaricidal and nematocidal activity.
Patent IL-85069-A0 (IL)
Title: Tricyclic benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing them
IPC: C07D487/10
Filed: 1988-01-11
Abstract: Novel tricyclic benzimidazoles of the formula I 
<IMAGE>
 in which
 R1 represents an optionally substituted phenyl ring, a naphthyl radical or a saturated or unsaturated heterocyclic 5-membered ring having 1-4 heteroatoms or a heterocyclic 6-membered ring having 1-5 heteroatoms, where the heteroatoms can be identical or different and denote oxygen, sulphur or nitrogen and, if desired, can carry an oxygen atom on one or more nitrogen atoms, and the 5- or 6-membered rings can optionally be substituted by one or more alkyl, alkoxy, alkylmercapto, hydroxyl, nitro, amino, halo or cyano groups or can be condensed with a phenyl ring to give a bicycle,
 or in the case in which X represents a bond, R1 in addition to the abovementioned groups also denotes a hydrogen atom, an alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, haloalkyl, alkoxyalkyl, carboxyalkyl, alkoxycarbonylalkyl, aminoalkyl, hydroxyalkyl, hydroxyl, mercapto, amino, alkylmercapto, alkylcarbonylamino, formylamino, alkylsulphonylamino, formylaminoalkyl, alkoxycarbonylaminoalkyl, alkylsulphonylaminoalkyl, alkoxycarbonylamino, trifluoromethyl or alkylcarbonylaminoalkyl group, X denotes a bond, an alkylene group, the vinylene group, the imino group -NH- or the amide group -CONH-, and
 A, B, C and D independently of one another denote carbon and nitrogen atoms which can be substituted by hydrogen, alkyl groups or cycloalkyl groups, where the carbon atoms can also carry hydroxyl or oxo groups or can be constituents of a 3-7-membered spirocycle, where the 6-membered ring containing A, B, C and D can be saturated, partially unsaturated or unsaturated,
 their tautomers and their physiologically tolerable salts of inorganic or organic acids, for the treatment of circulatory disorders, where they inhibit platelet and erythrocyte aggregation.
Patent IL-97154-A0 (IL)
Title: High strength steel alloy
IPC: C22C38/00
Filed: 1991-02-05
Abstract: A high strength, high fracture toughness steel alloy consisting essentially of, in weight percent, about C 0.2-0.33, Mn 0.20 max., Si 0.1 max., P 0.008 max., S 0.004 max., Cr 2-4, Ni 10.5-15, Mo 0.75-1.75, Co 8-17, Ce effective amount-0.030, La effective amount-0.01, Fe balance, and an article made therefrom are disclosed. A small but effective amount of calcium can be present in this alloy in substitution for some or all of the cerium and lanthanum. The alloy is an age-hardenable martensitic steel alloy which provides a unique combination of tensile strength and fracture toughness. The alloy provides excellent mechanical properties when hardened by vaccum heat treatment with inert gas cooling and has a low ductile-to-brittle transition temperature.
Patent IL-97751-A0 (IL)
Title: Amine derivatives
IPC: A61P9/06
Filed: 1991-04-02
Abstract: This invention concerns novel aminopyridinium compounds of the formula I wherein R<1>, R<2>, R<3>, R<5> and R<6> are selected from the following combinations: <CHEM>     (a) one of R<2> and R<6> is a basic group selected from amino, alkylamino, dialkylamino of up to eight carbon atoms, pyrrolidino, piperidino and morpholino, or is alkyl, alkenyl, alkoxyalkyl, alkoxy, alkylthio, phenyl, phenylalkyl, cycloalkyl or cycloalkylalkyl; and the other of R<2> and R<6> is hydrogen, alkyl or one of the above defined basic groups; R<1> is alkyl, alkenyl, cycloalkyl, phenyl, phenylalkyl, cycloalkylalkyl; and R<3> and R<5> are independently hydrogen, alkyl or alkenyl; (b) R<2> is a basic group as defined above, R<5> and R<6> together form alkylene or, together with the appendant carbon atoms of the pyridine ring, complete a benzene ring; R<1> has any of the meanings defined in (a) above; and R<3> is hydrogen, alkyl or alkenyl; and (c) R2 has any of the meanings defined above and R<6> is a group of the formula -NR<7>.A- in which A together with R<1> forms an ethylene, trimethylene or tetramethylene link and R<7> is hydrogen or alkyl; and R<3> and R<5> have, independently, any of the meanings defined in (a) above; and wherein R<4> is hydrogen, cycloalkylalkyl, alkyl, alkenyl, alkynyl or phenylalkyl; and Q is phenyl; or the group Q.N(R<4>)- together constitutes an azaheterocyclic moietyo; Y is a physiologically acceptable anion; and any one or more of said phenyl or benzene moieties may optionally be unsubstituted or bear one or more selected substituents.   The invention also includes certain closely related anhydro-base derivatives which, like the formula I componds, possess beneficial effects on the cardiovascular system. Also included are pharmaceutical compositions and processes for the manufacture of the various novel compounds.
Patent FI-20096334-A0 (FI)
Inventor: LEHTINEN KAISA
IPC: B41M/
Filed: 2009-12-15
Abstract: The invention relates to a method for manufacturing liquid- guiding structural layers by flexo or gravure printing on a substrate sheet, using a printing solution, which alters the properties of the substrate sheet in such a way that liquid flow is prevented in the area of the structural layers. The penetrability of the printing layer into the substrate sheet can be regulated by the printing-cylinder pressure and the composition of the printing solution. In the method it is possible to use printing solutions consisting of economical polymers and a solvent. In terms of printing technology, the invention is compatible with existing printing machines and is thus highly suitable for mass production.
Patent IL-109848-A0 (IL)
Title: Vitamin d compounds, their preparation and pharmaceutical and cosmetic compositions containing them
IPC: C07C49/477
Filed: 1994-06-01
Abstract: The invention relates to a new vitamin D compound of the general formula <CHEM>  wherein: R2 is a (C1-C3)alkyl group, a hydroxy(C1-C3)alkyl group, a (C1-C2)alkoxymethyl group or a (C2-C3)alkenyl or alkynyl group; R3 is a branched or non-branched, saturated or unsaturated aliphatic 3- to 5-membered hydrocarbon or oxahydrocarbon biradical, having at least 3 atoms in the main chain and being optionally substituted with one or more substituents selected from epoxy, fluoro and hydroxy;     iPr is an isopropyl group; and     A and B are each individually hydrogen atoms or methyl groups, or     A and B form together a methylene group. The invention further relates to a method of preparing these compounds and to their use in pharmacotherapy and cosmetics. <IMAGE>
Patent IL-110461-A0 (IL)
Title: Process for the preparation of pyrazole and its derivatives
IPC: C07D231/12
Filed: 1994-07-26
Abstract: PCT No. PCT/EP94/02708 Sec. 371 Date Feb. 15, 1996 Sec. 102(e) Date Feb. 15, 1996 PCT Filed Aug. 13, 1994 PCT Pub. No. WO95/06036 PCT Pub. Date Mar. 2, 1995A process for preparing pyrazole and its derivatives of the formula I    <IMAGE>  I  where R1, R2, R3 and R4 are each hydrogen, halogen, nitro, carboxyl, sulfonyl or C-organic radicals, from alpha,beta-unsaturated carbonyl compounds of the formula II    <IMAGE>  II  and hydrazine or hydrazine derivatives of the formula III H2N-NHR4 III wherein, initially without additional diluent, an alpha,beta-unsaturated carbonyl compound of the formula II is reacted with hydrazine or a hydrazine derivative of the formula III, and the resulting reaction mixture is reacted in another step with a mixture of sulfuric acid and iodine or a compound which liberates iodine or hydrogen iodide.
Patent IL-112637-A0 (IL)
Title: A pharmaceutical composition containing oxybutynin and methods for the preparation thereof
IPC: A61J3/06
Filed: 1995-02-14
Abstract: A solid oral sustained release oxybutynin formulation includes a sustained release matrix including a gelling agent, an inert pharmaceutical diluent, and a cationic cross-linking agent.
Patent IL-114753-A0 (IL)
Title: New use and new derivatives of imidazole their preparation the new intermediates obtained their use as medicaments and the pharmaceutical compositions containing them
IPC: A61P9/08
Filed: 1995-07-27
Abstract: PCT No. PCT/FR95/01034 Sec. 371 Date Jan. 31, 1997 Sec. 102(e) Date Jan. 31, 1997 PCT Filed Aug. 1, 1995 PCT Pub. No. WO96/04276 PCT Pub. Date Feb. 15, 1996The invention relates to the new use and the new products of formula (I):    <IMAGE>  (I)  in which: R1=represents hydroxyl, alkyl, alkenyl, alkynyl, alkoxy, alkylthio, formyl, cycloalkyl, optionally interrupted by heteroatoms, R2, R3 represent in particular halogen, mercapto, acyl, carboxy, nitro, cyano, amino, carbamoyl, R4, -OR4 with R4 representing in particular hydrogen, alkyl, alkenyl, alkynyl, acyl, amino, -(CH2)m1-S(O)m2-X-R10 with m1=0 to 4, m2=0 to 2, X represents a single bond or -NH-, -NH-CO-, -NH-CO-NH-, and R10 represents alkyl, alkenyl or aryl, and Y represents optionally substituted aryl, these products being in all the isomer forms and the salts, as medicaments.
Patent IL-125288-A0 (IL)
Title: Biological denitrification of water
IPC: C02F3/28
Filed: 1997-01-10
Abstract: Biological denitrification of water using one or more bioreactor units containing bioreactor media, a prefilter assembly containing prefilter media, and a slow sand filter containing sand filter media. Each bioreactor unit requires certain water flow related values and the bioreactor media must have certain material or dimensional characteristics. An air scouring process is constrained to predetermined parameter values to remove excess biomass material from the bioreactor media. The prefilter assembly also includes a flow distribution device for providing uniform water flow throughout the cross-section of the prefilter media. In one embodiment, the prefilter assembly and the slow sand filter assembly are semi-portable in that they have a reduced size with limited dimensions. This enables the prefilter assembly and the slow sand filter assembly to be made at a remote location and transported to the site at which water is to be denitrified. The semi-portable aspect of the slow sand filter assembly results from a number of structural aspects including being made of modular filter containers, thin, reinforced walls being made of weldable materials, lifting elements connected to the walls, a container floor supported by a platform and filtered water carrying pipes that communicate with a common pipe located outside of the filter container.
Patent IL-128636-A0 (IL)
Title: Multilayered wound dressing
IPC: A61F13/02
Filed: 1997-09-05
Abstract: A novel wound dressing includes a fibrous absorbent layer for absorbing wound exudate, an odor layer for absorbing odor and a barrier layer interposed the fibrous absorbent and barrier layers. Preferably the barrier layer is vacuum perforated and the fibrous absorbent layer is of highly absorbent fibres capable of absorbing 25 grams of exudate per gram of dressing.
Patent IL-128977-A0 (IL)
Title: Method of producing polyphenol-containing compositions
IPC: A61K36/00
Filed: 1997-09-19
Abstract: A flavonol-containing dry composition derived from wine and useful as a food supplement is provided wherein at least 25% of the composition derived from wine includes polyphenols and at least 1.0% w/w of the composition is flavonol.
Patent IL-141219-A0 (IL)
Title: Apparatus and a method for loading weights
IPC: A63B24/00
Filed: 2001-02-01
Abstract: Apparatus and a method for varying the load on an exercise machine is provided. The apparatus includes at least one load-bearing member having a plurality of receivers formed therein, and a plurality of weights in slidable communication with the at least one load-bearing member. Each of the weights has a weight selection device housed therein for selectably locking each of the weights to the receivers of the load-bearing member. <IMAGE>
Patent IL-142854-A0 (IL)
Title: Topology discovery in atm networks
IPC: H04L12/56
Filed: 2001-04-29
Abstract: A method for topology discovery in an ATM network, the method including identifying an active VC between two ATM network device ports, and maintaining a link between the ATM network device ports in a topology graph where the active VC has the same VPI/VCI at both of the ports.
Patent IL-148290-A0 (IL)
Title: A two-side multiple lamp type on-line internal qualities inspection system
IPC: G01N21/31
Filed: 2000-09-21
Abstract: An internal qualities inspection system having a receiving tray (2) for placing an inspecting object (F) thereon with a receiving seat (23) and a transmission light passage (21) formed in the receiving tray is arranged to detect light transmitted through the object from below the receiving tray. The inspection system is capable of efficiently detecting the transmission light from inside of each of inspecting objects of varied shapes and varied kinds by adjusting the quantity of light projected on the object according to its size and kind. The system includes in combination a light receiving part (4) and a calibration arrangement which are not affected by any disturbance light to ensure a highly reliable measuring accuracy. In the system, a light projecting part (3) is arranged to project light on the inspecting object from many lamps from both the right and left sides of a transport path (100); the light receiving part (4) has a light reducing filter (433) arranged between a condenser lens (41) and a spectrometer to adjust the quantity of light incident on the spectrometer; and calibration is made by retractably moving a white level calibrating plate forward to cover the upper surface of each of empty receiving trays when more than a predetermined number of empty receiving trays consecutively travel. <IMAGE>
Patent IL-164182-A0 (IL)
Title: Zymogenic nucleic acid detection methods, and related molecules and kits
IPC: C12Q1/6853
Filed: 1999-02-22
Abstract: This application provides methods of detecting and quantitatively determining a target nucleic acid sequence in a sample, which comprise contacting the sample with a primer and a zymogene which encodes, but which itself is the anti-sense sequence of, a catalytic nucleic acid sequence, so that when the target is present, a single amplified nucleic acid molecule is produced which comprises the sequences of both the target and catalytic molecules. This invention further provides a method of simultaneously detecting the presence of a plurality of target nucleic acid sequences in a sample. Finally, this invention provides molecules and kits for practicing the instant methods.
Patent IL-166307-A0 (IL)
Title: Preparation of 1h-imidazoÄ4,5-cÜquinolin-4-amines via novel 1h-imidazoÄ4,5-cÜquinolin-4-cyano and 1h-imidazo Ä4,5-cÜquinolin-4-cyano and 1h-imidazoÄ4,5-cÜquinolin-4-carboxamide intermediates
IPC: A61P37/02
Filed: 2003-07-28
Abstract: The invention relates to a process for the synthesis of 1H-imidazo[4,5-c]quinoline 4-cyano and 1H-imidazo[4,5-c]quinoline 4-carboxamide intermediates useful in preparing 1 H-imidazo[4,5-C]quinoline 4-amines, a process for preparing 1H-imidazo[4,5-C]quinoline 4-amines using such intermediates; and, to the 1H-imidazo[4,5-c]quinoline 4-cyano and 1H-imidazo[4,5-c]quinoline 4-carboxamide intermediates. More particularly, the invention relates to a process for the preparation of 1-isobutyl-1H-imidazo[4,5-C]quinoline 4-amine (Imiquimod) using two intermediates, 1-isobutyl-1H-imidazo[4,5-c]quinoline 4-cyano and 1-isobutyl-1H-imidazo[4,5-c]quinoline 4-carboxamide, and to the said intermediates.
Patent IL-196993-A0 (IL)
Title: Decorative laminate and methods of producing the same
Filed: 2009-02-11
Abstract: A decorative laminate, and method for making the same, includes a core layer, a print layer, an overlay layer, and a luminescent layer. The print layer includes patterns printed thereon using conventional ink. In some embodiments, the overlay layer is impregnated with a resin that includes photoluminescent material of a single color which, when exposed to UV light, causes the single color to be visible throughout. The luminescent layer includes patterns of photoluminescent materials of different colors. In the embodiments where the overlay layer includes a resin with a photoluminescent material, the different colored patterns of the luminescent layer are simultaneously visible with the single color of the overlay layer when exposed to UV light.
Patent IL-208171-A0 (IL)
Title: Process for the synthesis of ethynylcyclopropane
Filed: 2010-09-15
Abstract: Ethynylcyclopropane is prepared in a two-step process by reacting (1,1-dimethoxyethyl)-cyclopropane with a thiol and eliminating the thiol from the intermediate.
Patent IL-214325-A0 (IL)
Title: Humanized anti-cmet antagonists
Filed: 2011-07-28
Abstract: The invention provides therapeutic anti-c-met antibodies, and compositions comprising and methods of using these antibodies.
Patent RO-125671-A0 (RO)
Title: Automated system for repairing roadway surfaces and applying cold asphaltic mixtures
Inventor: NEAGU VALENTIN
IPC: E01C23/06
Filed: 2010-04-26
Abstract: The invention relates to an automated system for repairing roadway surfaces and applying asphaltic mixtures. According to the invention, the system consists of four operational modules placed on the frame of an equipment meant to repair roadway surfaces, namely: a roadway surface securing and protection module on which there are made repairs consisting of a flexible rubberized textile protection apron, hydraulically actuated by six pistons, an ultrasonic scan module which displaces horizontally scanning the roadway surface to be repaired, by determining the shape and the indentations thereof, a multipurpose module of carrousel type, which is displaced both horizontally and vertically, positioning at the repair place some devices specific to asphaltic repairs, it is equipped with, namely: a device for mechanical processing for uncovering the roadway surface to be repaired, a device for pouring the asphaltic mixture and a compaction device provided with an evenness sensor for limiting compaction at the existing roadbed level and a module for cleaning the surfaces of intervention and storing the residues resulting after the processing.
Patent RO-127539-A0 (RO)
Title: Scm profile
Inventor: ZAHIU NICULAE
IPC: E04C3/07
Filed: 2011-10-07
Abstract: The invention relates to a metal element to be used in constructions for making posts and frame struts as well as independent beams and supporting pillars. According to the invention, the metal element comprises some rolled open profiles (A and B) mounted face to face, in an upside down position to each other, each of the two profiles (A and B) having a central web (1) provided with some central equally spaced fastening holes (a) in which there are introduced some screws with nuts or some rivets, said central web (1) being linked to some inclined walls (2 and 3) which are continued by some vertical walls (4 and 5) continued by some horizontal bases (6 and 7) provided with some U-shaped stiffening grooves (8 and 9), namely an upper groove and a lower groove, respectively, which are made so that upon mounting the open profiles (A and B), the lower groove (9) of the first open profile (A) is accommodated within the upper groove (8) of the second open profile (B) and the lower groove (9) of the second open profile (B) is accommodated within the upper groove (8) of the first open profile (A), where in the upper and lower grooves (8 and 9) there are provided some similar oblong axial slots (b and c) whose axes correspond to the axes of the fastening holes (a), some self-cutting screws (11) or some rivets being introduced between the central fastening holes (a), as well as between the oblong slots (b and c), along the axes thereof and, at both ends of the open profiles (A and B) there being provided some individual nuts (13 and 14) and some fixing plates (15 and 16) provided with some threaded holes.
Patent RO-131192-A0 (RO)
Title: Pharmaceutical product with strong anti-inflammatory and antialgic action: diclofenac gel forte
Inventor: MELLES MELINDA
IPC: A61P29/00
Filed: 2016-02-22
Abstract: The invention relates to a pharmaceutical product with strong anti-inflammatory and antialgic action. According to the invention, the product comprises 4.1...5.1% diclofenac sodium, 0.7...0.9% rosemary essential oil, 0.7...0.9% sage essential oil, dissolved in 10...15% pharmaceutical ethyl alcohol 96%, 1.8...2.2% camphor and 0.9...1.0% menthol, the resulting solution being embedded in a gel consisting of 0.9...1.1% carbopol 940 and 0.065...0.085% sodium hydroxide dissolved in 70...80.8% distilled water.
Patent AP-2002002551-A0 (AP)
Title: Pump valves.
Inventor: PEMBERTON PIGOTT CRISPIN ROBERT
Filed: 2002-06-20
Abstract: A flap valve for use in a reciprocating pump is provided having a perforated rigid plate with a resilient flap secured thereto. The flap valve is configured so that the flap is biased towards the plate against which the flap seals in its closed position.
Patent MA-45803-A1 (MA)
Title: Pyrido [3,4-b] indoles substitués pour le traitement de troubles du cartilage
Inventor: RITZELER OLAF
IPC: C07D519/00
Filed: 2017-11-02
Abstract: La présente invention concerne des 9h-pyrido [3,4-b] indoles à substitution 8-aryle et 8-hétéroaryle de formule (i), dans laquelle a, e, g, r1 à r6 et r10 sont tels que définis dans les revendications, qui stimulent la synthèse de la chondrogenèse et de la matrice cartilagineuse et peuvent être utilisés dans le traitement de troubles et d'affections du cartilage dans lesquels une régénération du cartilage endommagé est souhaitée, par exemple des maladies articulaires telles que l'arthrose. L'invention concerne en outre des procédés de synthèse des composés de formule (i), leur utilisation comme composés pharmaceutiques et des compositions pharmaceutiques les comprenant.