baber/WOPTO huggingface dataset:
Patent MA-40897-A (MA)
Title: Unité de dispositif de médicaments contenant de la quinagolide
Inventor: ARCE SAEZ JOAN CARLES
IPC: A61K9/00
Filed: 2015-11-05
Abstract: La présente invention est basée sur l'identification d'une cohorte de copolymères séquencés de polyuréthane qui sont particulièrement adaptés pour utilisation dans des unités médicament-dispositif polymères pharmaceutiques et qui permettent un contrôle amélioré de la libération de médicament. En particulier, l'invention concerne une unité médicament-dispositif polymère comprenant un copolymère séquencé de polyuréthane pouvant être obtenu par réaction conjointement d'un poly(oxyde d'alkylène) ; un composé difonctionnel ; un isocyanate difonctionnel ; et facultativement un copolymère séquencé comprenant des blocs de poly(oxyde d'alkylène) ; et du quinagolide en tant qu'agent actif pharmaceutique. Les unités médicament-dispositif peuvent avoir une application dans le traitement et/ou la prévention de l'endométriose.
Patent MA-46646-A (MA)
Title: Machine thermique configurée pour réaliser des cycles thermiques et procédé pour réaliser des cycles thermiques au moyen d'une telle machine thermique
Inventor: OLIVOTTI SERGIO
IPC: F01C1/18
Filed: 2018-06-12
Abstract: L'invention concerne une machine thermique (121) pour réaliser un cycle thermique. Cette machine thermique fonctionne avec un fluide thermique et comprend une unité d'entraînement (1) pourvue d'un premier rotor (4) et d'un second rotor (5), chacun ayant trois pistons (7a, 7b, 7c; 9a, 9b, 9c) qui peuvent coulisser dans une chambre annulaire (12), les pistons délimitant six chambres à volume variable (13', 13", 13"'; 14', 14", 14"'). L'unité d'entraînement comprend une transmission configurée pour convertir le mouvement rotatif avec des première et seconde vitesses angulaires variables périodiquement (ω1, ω2) respectives desdits premier et second rotors (4, 5), décalées l'une de l'autre, en un mouvement rotatif à une vitesse angulaire constante. La machine thermique comprend en outre un réservoir de compensation (44), configuré pour accumuler le fluide thermique comprimé provenant de l'unité d'entraînement, un régénérateur (42) configuré pour préchauffer le fluide thermique, un dispositif de chauffage (41) configuré pour surchauffer le fluide thermique circulant dans la bobine en serpentin, un brûleur (40) configuré pour fournir l'énergie thermique nécessaire au dispositif de chauffage (41). Le régénérateur (42), en communication fluidique avec l'unité d'entraînement (1), est en outre configuré pour acquérir de la chaleur d'énergie à partir du fluide thermique évacué et pour l'utiliser pour préchauffer le fluide thermique à envoyer au dispositif de chauffage (41). L'invention concerne en outre un procédé de réalisation d'un cycle thermique au moyen de ladite machine thermique.
Patent MX-158468-A (MX)
Inventor: CLARK BRIAN
IPC: G01V3/30
Filed: 1985-11-19
Abstract: An electromagnetic logging apparatus is disclosed which employs dielectric-filled slot antennas, in conjunction with tuning elements, to obtain improved operation. The apparatus can be used to measure the dielectric constant of formations surrounding a borehole.
Patent PH-21560-A (PH)
Title: Epimeric azahomoerythromycin a, derivatives and intermediate therefor
Inventor: MICHAEL BRIGHT GENE
IPC: C07H17/08
Filed: 1985-02-28
Abstract: Antibacterial 4 sec -epi-9-deoxo-9a-methyl-9a-aza-9a-homo-erythromycin A, pharmaceutically-acceptable salts thereof, pharmaceutical compositions comprising antibacterially-effectife amounts thereof, a method of treatment of bacterial infections with antibacterially effective amounts thereof, and intermediates for the synthesis thereof from erythromycin A.
Patent PH-22159-A (PH)
Title: 9- or 11- substituted apovincaminic acid derivatives
Inventor: ANDRAS VEDRES
IPC: C07D461/00
Filed: 1985-07-11
Abstract: 1. Claims for the Contracting States : BE, CH, DE, FR, GB, IT, LI, NL, SE Racemic or optically active 9- and/or 11-substituted apovincamic acid derivatives having the general formula  see diagramm : EP0173824,P11,F1  wherein R is a nitro or amino group in position 9 or 11, and the salts thereof. 1. Claims for the Contracting State : AT A process of producing racemic or optically active 9- and/or 11-substituted apovincamic acid derivatives having the general formula  see diagramm : EP0173824,P11,F3  wherein R is a nitro or amino group in position 9 or 11, and salts thereof, characterized in that apovincamic acid having the formula  see diagramm : EP0173824,P11,F4  is nitrated and the resulting 9- and/or 11-(nitro)- apovincamic acid(s) is or are optionally reduced, optionally after it has or they have been isolated from the reaction mixture and, optionally the resulting 9- and/or 11-substituted apovincamic acid derivatives having the general formula I are transformed to acid addition salts or quaternary salts and/or metal salts and/or ammonium salts and/or the resulting salts of 9- and/or 11-substituted apovincamid acid derivatives having the general formula I are transformed to the free 9- and/or 11-substituted apovincamic acid derivatives having the general formula I or to other acid addition salts and/or quaternary salts and/or metal salts and/or ammonium salts and/or the resulting racemic 9- and/or 11-substituted apovincamic acid derivatives having the general formula I and/or the acid addition salts and/or quaternary and/or metal salts and/or ammonium salts are dissociated to its or their optical antipodes and/or the corresponding optically active compounds are racemized to form stereo-isomers.
Patent PH-25583-A (PH)
Title: Octahydro-pyridine diphosphomate compounds, pharmaceutical compositions, , methods for treating abnormal calcium, phosphate metabolism
Inventor: EBETINO FRANK HALLOCK
IPC: C07F9/547
Filed: 1987-12-18
Abstract: The present invention relates to novel compounds having nitrogen-containing, saturated bicyclic cylopentane-fused rings which are geminally disubstituted with phosphonate groups. Most preferred compounds of the present invention have the general structure: <CHEM>   The present invention further relates to pharmaceutical compositions containing these novel compounds. Finally, this invention relates to methods for treating or preventing diseases characterized by abnormal calcium and phosphate metabolism by utilizing a compound or pharmaceutical composition of the present invention.
Patent TR-23995-A (TR)
IPC: D06F73/02
Filed: 1988-06-06
Abstract: A method of ironing articles of clothing by means of opposite hot air jets directed from top to bottom onto both sides of the articles, preferably by an angle of incidence of about 45 DEG  to the plane thereof, said hot air jets causing the treated articles to be put in vertical tension. An apparatus for ironing articles of clothing by this method includes, in particular, a plurality of fans (9) each of which draws in hot air and discharges it into a pair of opposite hollow bulkehads (11), these opposite bulkheads (11) evenly conveying the hot air through associated conveying nozzles (12) so that it impinges from top to bottom upon both sides of the articles to be treated.
Patent UY-32351-A (UY)
Title: Compuestos de pirimidinil indol para uso como inhibidores de atr
Inventor: FOOTE KEVIN MICHAEL
IPC: A61K31/404
Filed: 2009-12-21
Abstract: Se proporcionan compuestos de pirimidinil indol de Fórmuls (I), o sales farmacéuticamente aceptables de los mismos, procesos para su preparación, composiciones farmacéuticas que los contienen y su uso en terapia.
Patent UY-32660-A (UY)
Title: Derivados aminobutricos sustituidos como inhibidores de neprilisina
Inventor: COPPOLA GARY MARK
IPC: A61K31/197
Filed: 2010-05-26
Abstract: La presente invención proporciona un compuesto de la fórmula I, o una sal farmacéuticamente aceptable del mismo, en donde R1, R2, R3, X y n se definen en la presente. La invención también se refiere a un método para la elaboración de los compuestos de la invención, y a sus usos terapéuticos. La presente invención proporciona además una combinación de agentes farmacológicamente activos y una composición farmacéutica
Patent UY-34131-A (UY)
Title: Dosificación y administración de anticuerpos anti-erbb3 en combinación con inhibidores de tirosina quinasa.
Inventor: WILLIAM KUBASEK
IPC: A61K31/517
Filed: 2012-06-15
Abstract: Se proporcionan métodos y composiciones para el tratamiento clínico de NSCLC usando anticuerpos anti-ErbB3 combinados con el uso de TKI tales como erlotinib o gefitinib.
Patent UY-38282-A (UY)
Title: Compuestos y métodos para la reducción de la expresión de lrrk2
Inventor: SUSAN M FREIER
IPC: C07H21/00
Filed: 2019-06-27
Abstract: Se proporcionan compuestos, métodos y composiciones farmacéuticas para reducir la cantidad o la actividad del ARN de LRRK2en una célula o animal, y en determinados casos para reducir la cantidad de proteína LRRK2 en una célula o animal. Tales compuestos, métodos y composiciones farmacéuticas son útiles para mejorar al menos un síntoma o característica de una enfermedad neurodegenerativa. Dichos síntomas y características incluyen ataxia, neuropatía y formación de agregados. Tales enfermedades neurodegenerativas incluyen enfermedad de Parkinson.
Patent YU-32396-A (YU)
Inventor: PILAR LUPON ROSES
IPC: C07D403/12
Filed: 1996-05-30
Abstract: Pronalazak se odnosi na nove polimorfe I i II Lesopitron dihidrohlorida koji su naznačeni njihovim infracrvenim spektrima i njihovim difrakcionim putanjama X-zraka. Dobijaju se kristalizovanjem Lesopitron dihidrohlorida. Odnosi se takodje i na oblike I-hidrata i II-hidrata koji se dobijaju iz odgovarajućih polimorfa, koji imaju sadržaj vode od 3 do 6% i od 1.5 do 2.5%. Ovi proizvodi se koriste u humanoj medicini uglavnom usled njihovog farmakološkog delovanja na centralni nervni sistem.
Patent YU-39101-A (YU)
Title: Aromatic heterocyclic compounds as antiinflamartory agents
Inventor: CIRILLO PIER F
IPC: A61K31/4439
Filed: 1999-12-09
Abstract: Disclosed are novel aromatic heterocyclic compounds of formula (I) wherein Ar1, Ar2, L, Q and X are described herein. The compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are processes of making such compounds.
Patent YU-45794-A (YU)
Title: Postupak za sintezu kopolimera maleinske i akrilne kiseline
Inventor: DUSAN MILJKOVIC
IPC: C02F5/10
Filed: 1994-07-18
Abstract: POSTUPAK ZA SINTEZU KOPOLIMERA MALEINSKE I AKRILNE KISELINE, cilj pronalaska je sinteza novog tipa kopolimera maleinske i akrilne kiseline koji sadrže 60 do 100% maleinatnih jedinica, odnosno 40 do 0% akrilatnih jedinica, obračunato na sumu obe jedinice u kopolimeru. Ovakvi kopolimeri pokazuju izrazite tehno-ekonomske prednosti u odnosu na ranije opisane kopolimere akrilne i maleinske kiseline. Prema optimizovanom postupku sinteze pomenutih kopolimera primenjuju se veoma koncentrovani alkalni rastvori maleinata (najbolje iznad 60%), vodonik peroksid i natrijumpersulfat kao katalizatori, i reakciona temperatura od 105 do 115В°C. Dobijeni kopolimeri imaju prosečne molekulske mase oko 20000 (dvadeset hiljada), a CCDC im iznosi u proseku oko 17 ml 0,25 M calcijum acetatapo 1 g kopolimera. Dobijeni kopolimeri pogodni su za primenu kao inhibitori inkrustacija, disperzanti i jonoizmenjivači.
Patent YU-52292-A (YU)
Title: Mini električni kotao
Inventor: SPASOVIC S
Filed: 1992-05-19
Abstract: Pronalazak se odnosi na mini električni kotao sa kompatibilnim grejnim elementom, kaosastavnim delom postojećeg klasićnog sistema etažnog ili centralnog vodenog grejanja sa standardnim radijatorima i spada u oblast grejanja. Predmet pronalaska obuhvata u zavojnici (151) donjeg slobodnog čepa (16) kućišta (15), u postojeći sistem etažnog ili centralnog vodenog grejanja stalno priključenog radijatora, postavljeni nosač (71) električnog cevnog grejača (72) sa zaptivnom učvršćenim ovim grejačem (72) kao i cevi (73) termostata, pri čemu je sa druge strane nosača (71) učvršćeno kućište (31) sa međusobno vijcima (13) spojenim bocnim stranama (8,10) kao i prednjom stranom (3) i zadnjom stranom (12). U kućištu (31) je postavljen prekidač (2) sa sijalicom kao i termostat (6) sa dugmetom (1) i sondom (61) umetnutom u cev (73) za jedno sa topiljivim osiguračem (14), čiji su električni priključci (141) zajedno sa električnim priključcima (62, 74) termostata i cevnog grejača odgovarajuće električki spojeni i povezani sa elektricnim klemama (111) priključnog kabla (11) sa utikačem (13).
Patent YU-58288-A (YU)
Inventor: BORISLAV DZODZO A
Filed: 1988-03-23
Abstract: U vratilni vod je ugrađen zglob (5) ispred propelerskog vratila (25) čime je omogućeno ugaono zakretanje tog vratila u odnosu na pogonsko vratilo (23). Za dato postrojenje je predložen niz specifičnih reduktorsko-zupčaničkih i hidrauličkih zglobova a takođe i niz nosača (331) propelerskog vratila koji se sastoje od stacionarnog i zakretnog sklopa čija povezna i zakretna osa se poklapa sa osom uglovnosti zgloba. Dok postojeći sistemi krmilarenja broda krmilarećim propelerom (Schottel i dr.) imaju vertikalni vod višestruko "izlomljen" u vertikalnoj ravni, predloženo postrojenje predstavlja "direktan pogon" kod koga je celokupan vratilni vod horizontalan što čini postrojenje jednostavnijim, pouzdanijim i sposobnim za prenos velikih snaga. U izvesnim slučajevima postoje i kapslovani reduktorsko-krmilareći-propulzijski "kompakti" koji se jednostavno prikače za krmu ili umetnu u nju čak i kad je brod na vodi.
Patent YU-59985-A (YU)
Title: Process for making live purifyed vaccine for marek's disease
Inventor: DE BOER G F
IPC: A61K39/255
Filed: 1985-04-09
Abstract: The invention relates to a highly immunogenic virus preparation derived by attenuation employing serial passages in avian cell cultures and six plaque purification steps from a Marek's disease virus strain, belonging to Avian Herpesvirus serotype-1. The original virus strain MDV CVI-988 was recovered from a healthy chicken (Avian Disease 16:108-125,1972).The live purified Marek's disease vaccine so obtained is innocuous for specific pathogen free Rhode Island Red chickens which are highly susceptible for development of Marek's disease tumours. The monovalent virus preparation, according to the invention, demonstrated in comparison with Marek's disease vaccines based on the same strain, currently in use at a lower cell passage level, an improved protective efficacy against challenge infection by two representatives of virulent Marek's disease virus.The monovalent virus preparation, according to the invention, provided significantly better protection than current MDV CVI-988 vaccine to challenge infection with a representative of the group of newly emerging very virulent strains of Marek's disease virus, MDV RB/1B. The monovalent virus strains of Marek's disease virus, MDV RB/1B. The monovalent virus preparation, according to the invention, provided significantly better protection than is HVT FC126 vaccine to challenge infection with another representative of the group of very virulent MD viruses, MDV Tun.
Patent YU-65993-A (YU)
Title: Završni deo indikatora doziranja šprica
Inventor: HARRIS D D
IPC: A61M5/315
Filed: 1993-10-19
Abstract: ZAVRŠNI DEO INDIKATORA DOZIRANJA ŠPRICA, pronalazak se odnosi na indikator doze kod šprica za potkožno ubrizgavanje tečnosti. Ovaj indikator je izveden da podesi dozu i pritiskom ubrizga tu dozu. Indikator sadrži sredstvo za proizvodjenje zvuka podešeno da proizvede zvuk kada je dugme pritisnuto do kraja doze, i sredstvo za ponovno podešavanje sredstva (a) kada prestane pritisak na dugme nakon što je doza ubrizgana. Završni deo indikatora prilagodjen je da prihvati dugme šprica za ubrizgavanje sadrži gornji deo, elastične krake koji normalno vise sa gornjeg dela gde elastični kraci imaju sredstvo za sadejstvo istovremeno i drže elastične krake u predodredjenom položaju na dugmetu pošto je pritisnut gornji deo sve do kraja doze a na kraju doze su oslobodjeni iz predodredjenog položaja i prouzrokuju zvuk, sredstvo za povraćaj elastičnih kraka u predodredjeni položaj na dugmetu za doziranje kada je gornji deo oslobodjen pritiska.
Patent YU-93690-A (YU)
Title: Kristalni deoksispergvalin i postupak za njegovo pripremanje
Inventor: IKAI KATSUSHIGE
IPC: C07C277/08
Filed: 1990-05-14
Abstract: KRISTALNI DEOKSISPERGVALIN I POSTUPAK ZA NJEGOVO PRIPREMANJE, posebno u obliku trihidrohlorida, sa odličnom antitumornom i imunosupresivnom aktivnošću, kao i na postupak ya njegovo dobijanje. Postupak obuhvata kristalizaciju praška u vodi suspendovanog sirupa deoksispargvalin trihidrohlorida, u prisustvu vode i organskog rastvarača koji se meša sa vodom, ili koji se rastvara u vodi.
Patent BE-884669-A (BE)
IPC: C12M1/16
Filed: 1980-08-07
Abstract: A granular carrier is contacted in a reaction space with a continuous stream of liquid which contains a sufficiently wide flora of microorganisms and sufficient nutrients for the growth and /or preservation of the microorganisms until a sufficiently thick layer of microorganisms is attached to the carrier, while in the liquid 0.1-1.5 kW of mechanical energy per m<3> of reactor liquid, is dissipated at least partly in the form of gas bubbling through the liquid and the residence time of the liquid in the reaction space is kept lower than the reciprocal maximum growth rate of the microorganisms. More preferably an aerobic biomass attached to a carrier is produced, by applying liquids, wherein the growth rate is not limited by the concentration of nutrients and by adjusting a residence time of the liquid in the reactor of below 45 minutes. 
<??>The process can be applied for the production of all kinds of biomass attached to a carrier, e.g. biomasses as are applied in the biological purification of waste-water, aerobic biomass, anaerobic biomass, nitrificating biomass and denitrificating biomass, as well as biomasses forming a desired metabolic product which inhibits its own production rate at higher concentrations, e.g. biomass for the production of alcohol.
Patent BE-898144-A (BE)
Title: Colonne de support de siege reglable en hauteur.
IPC: A47C3/22
Filed: 1983-11-03
Abstract: L'invention a trait à une colonne de support de siège qui contient, dans un tube-fourreau (1), un tube-pivot (7) pouvant tourner et se déplacer et portant la coquille de siège. Le tube-pivot (7) porte un verrouillage à rouleaux (8) pouvant être amené en prise avec une douille intermédiaire (3) qui peut tourner et se déplacer dans le tube-fourreau (1) et pouvant être dégagé de cette douille. La douille intermédiaire (3) est supportée à rotation dans le tube-fourreau (1) par un dispositif amortisseur (6).
Patent BE-900445-A (BE)
Title: Pair of compasses for drawing - includes long screw adjustment controlling separation between arms and points
IPC: G01B3/16
Filed: 1984-08-28
Abstract: The pair of compasses includes a long screw (VSF) retained in a cylindrical component at one end ()C), to which the two arms of the compasses (JC) are attached by a pivoting joint. The other, upper end of the long screw is attached to the operating button (BC) by which the compass setting may be altered. - The two arms are also attached by short linkages (RC) to a coupling piece which is attached to the vertical support of the mechanism. As the operating button, and hence the screw are rotated, the pivoting joint linking the two arms is moved along the screw, thus changing the angle between thearms and their separation.
Patent BE-901917-A (BE)
Title: Sels d'erythromycine avec des derives de l'acide acetique, procede pour leur preparation et compositions pharmaceutiques en contenant.
IPC: C07D333/36
Filed: 1985-03-12
Abstract: Sels d'érythomycine avec les acides ''(2-oxo-3-tétrahydrothiénylcarbamoyl) alkylthio'' acétiques, de formule I, leur procédé de préparation et compositions pharmaceutiques en contenant, ces compositions étant utilisables à titre d'agents antibiotiques et mucolytiques.
Patent BE-905745-A (BE)
Title: Procede de preparation de dentiers a plaques.
Inventor: ATSUSHI YAMASHITA
IPC: A61K6/90
Filed: 1986-11-13
Abstract: Pour préparer directement un dentier, ou utiles de manière appropriée des résines photo-polymérisables possédant des viscosités variées, et on utilise comme matière d'empreinte un produit pateux de résines photo-polymérisables possédant différentes viscosités avec la préparation d'une plaque de base - la formation d'une partie de rebord alvéolaire - l'agencement de dents artificielles - la formation d'une partie gingivale, l'empreinte des détails de la surface du muqueuse de la bouche étant reproduite avec une grande fidélité et ensuite polymérisée et cuite par des faisceaux d'énergie active pour une utilisation en tant que surface de résine.
Patent BE-766714-A (BE)
Title: Loom for producing relief patterned pile fabrics
IPC: D03D27/00
Filed: 1971-05-04
Abstract: The loom has a lower row of parallel loop forming fingers and an upper weft-wise extending row of parallel yarn guides which are used for inserting two grps. of pile yarns into a base weave, of grps. of warps traversed by double wefts, to produce a loop pile. The yarn guides are movable laterally and vertically either individually together or in grps. to insert pile yarn loops into the base weave such that they extend over one or more grps. of wefts. The pile yarns of each grp. may be inserted differently in different regions of the cloth to produce a variety of complicated relief patterned piles.
Patent CA-1057292-A (CA)
Title: 2-amino thiazoles
Inventor: CASTAIGNE ALBERT R J
IPC: C07D277/18
Filed: 1974-05-15
Granted: 1979-06-26
Abstract: Dérivés de l'amino-2 thiazole répondant à la formule générale: (I) dans laquelle R est un groupe de formule: relié, à atome de soufre par son deuxième atome de carbone, R1 et R2, identiques ou différents l'un de l'autre, sont de l'hydrogène ou des radicaux, éventuellement halogénés et/ou hydroxylés, alcényle, alcoyle, cycloalcoyle, aryle ou arylalcoyle ou forment, ensemble avec l'atome d'azote auquel ils sont reliés, un noyau morpholino, méthyl-4 pipérazino ou pipérazino, et R3 et R4, identiques ou différents l'un de l'autre, sont de l'hydrogène, alcoyle ou cycloalcoyle, ou forment, ensemble avec l'atome d'azote auquel ils sont reliés, un noyau morpholino, pipéridino ou pyrrolidino, pipérazino, phénylpipérazino, triflurométhylphénylpipérazino, halophénylpipérazino ou méthoxyphénylpipérazino, chaque fois qu'ils sont obtenus par un procédé selon la revendication 1 ou ses équivalents chimiques manifestes. Les dérivés selon l'invention jouissant de propriétés antiinflammatoires et hypocholeatérolémiantes précieuses.
Patent CA-1048331-A (CA)
Title: Method for fabricating minute openings in integrated circuits
Inventor: MAGDO INGRID E
IPC: H01L21/306
Filed: 1974-11-13
Granted: 1979-02-13
Abstract: A METHOD FOR FABRICATING MINUTE OPENINGS          IN INTEGRATED CIRCUITS                 Abstract of Disclosure A method in the fabrication of integrated circuits for forming small openings through electrically insula-tive passivating layers on semiconductor surfaces.  First and second layers of different insulative material are formed on the semiconductor surface.  Then, a first slot extending through the second or top layer is formed by chemical etching through an etch-resistant mask with an etchant which selectively etches the material in the top layer.  The top layer is then covered with a photoresist mask having a second slot which crosses the first slot, and the structure is subjected to chemical etching through the photoresist mask with an etchant that selec-tively etches the material in the first or bottom layer to, thereby, form a small opening through this bottom layer which is defined by the intersecting portions of the first and second slots.