baber/WOPTO huggingface dataset:
Patent AU-2014229233-A1 (AU)
Title: Pyridine derivatives as rearranged during transfection (RET) kinase inhibitors
Inventor: EIDAM HILARY SCHENCK
IPC: C07D401/12
Filed: 2014-03-14
Abstract: This invention relates to novel compounds which are inhibitors of the Rearranged during Transfection (RET) kinase, to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy, alone or in combination, for the normalization of gastrointestinal sensitivity, motility and/or secretion and/or abdominal disorders or diseases and/or treatment related to diseases related to RET dysfunction or where modulation of RET activity may have therapeutic benefit including but not limited to all classifications of irritable bowel syndrome (IBS) including diarrhea-predominant, constipation-predominant or alternating stool pattern, functional bloating, functional constipation, functional diarrhea, unspecified functional bowel disorder, functional abdominal pain syndrome, chronic idiopathic constipation, functional esophageal disorders, functional gastroduodenal disorders, functional anorectal pain, inflammatory bowel disease, proliferative diseases such as non-small cell lung cancer, hepatocellular carcinoma, colorectal cancer, medullary thyroid cancer, follicular thyroid cancer, anaplastic thyroid cancer, papillary thyroid cancer, brain tumors, peritoneal cavity cancer, solid tumors, other lung cancer, head and neck cancer, gliomas, neuroblastomas, Von Hippel-Lindau Syndrome and kidney tumors, breast cancer, fallopian tube cancer, ovarian cancer, transitional cell cancer, prostate cancer, cancer of the esophagus and gastroesophageal junction, biliary cancer, adenocarcinoma, and any malignancy with increased RET kinase activity.
Patent AU-2014229502-A1 (AU)
Title: Compositions and Methods for Enhancing the Therapeutic Potential of Stem Cells
Inventor: VAN DEN BOS CHRISTIAN
IPC: A61K31/437
Filed: 2014-03-13
Abstract: The invention encompasses compositions and method of treating a vascular disease such as peripheral artery disease, The methods involve- administering to a patient in need thereof, an effective amount of a composition comprising a population of cells such as mesenchymal stem cells (MSCs) and a non-muscle myosin 0 antagonist such as blebbistatin. Non-muscle myosin II antagonists are disclosed to surprisingly and dramatically accelerate MSC-triggered regeneration of damaged tissues arid unexpectedly and drastically reduce severe complications of stem cell treatment.
Patent AU-2014229776-A1 (AU)
Title: Downhole catching apparatus
Inventor: WEBSTER OLIVER
IPC: E21B34/14
Filed: 2014-03-14
Abstract: A downhole catching apparatus (20) comprises a plurality of radially moveable seat members (26) arranged circumferentially around a longitudinal axis, wherein the seat members are moveable between a radially extended configuration which permits passage of an object therethrough and a radially retracted configuration which permits an object to be caught by the apparatus. A releasable lock arrangement (44) is provided for releasably retaining the seat members in the radially extended configuration.
Patent AU-2014233500-A1 (AU)
Title: Methods of using Zscan4 for rejuvenating human cells
Inventor: KO MINORU S H
IPC: C12N15/11
Filed: 2014-03-14
Abstract: The present disclosure relates to methods for increasing telomere length in one or more human cells and/or increasing genome stability of one or more human cells, for example by contacting one or more human cells with an agent that increases expression of Zscan4 in the one or more human cells. Methods of treating a subject in need of telomere lengthening, treating a disease or condition associated with a genomic and/or chromosome abnormality, of rejuvenating one or more human cells, of rejuvenating tissues or organs, and of rejuvenating a subject in need thereof, for example by contacting one or more human cells in the subject with an agent that increases expression of Zscan4, or by administering to a subject in need thereof, an agent that increases expression of Zscan4 are also provided.
Patent AU-2014238453-A1 (AU)
Title: Smart HVAC manifold system
Inventor: YENNI EDWARD
IPC: G06F19/00
Filed: 2014-01-21
Abstract: The smart HVAC manifold system for servicing air conditioning systems is designed to dynamically manage the data acquisition process and to measure and calculate the performance indicators and output as the load conditions and or equipment operation change taking into account variables in the installation that can impact performance. Both visually and by a very specific data set the performance of the equipment and the installation can quickly be assessed and specific problems identified along with suggestions of typical faults or problems that may need addressed by the technician.
Patent AU-2014240238-A1 (AU)
Title: A body-biased slicer design for predictive decision feedback equalizers
Inventor: HEKMAT MOHAMMAD
IPC: H04L27/00
Filed: 2014-10-01
Abstract: 73957/ S1421 A predictive decision feedback equalizer using body bias of one or more field effect transistors (FETs) to provide an offset for a predictive tap. In one embodiment, a predictive tap of the predictive decision feedback equalizer includes a differential amplifier composed of two FETs in a differential amplifier configuration, and the body bias of one or both FETs is controlled to provide an offset in the differential amplifier. In one embodiment a current DAC driving a DAC resistor is used to provide the body bias voltage, and a feedback circuit, including a replica circuit forming the maximum possible DAC output voltage, is used to control the bias of the current sources of the current DAC. 2062656vl Ln) mW +C
Patent AU-2014284409-A1 (AU)
Title: Method and apparatus for facilitating voice user interface design
Inventor: BROWN KATHY L
IPC: G06F40/20
Filed: 2014-07-01
Abstract: A computer implemented method and an apparatus for facilitating voice user interface (VUI) design are provided. The method comprises identifying a plurality of user intentions from user interaction data. The method further comprises associating each user intention with at least one feature from among a plurality of features. One or more features from among the plurality of features are extracted from natural language utterances associated with the user interaction data. Further, the method comprises computing a plurality of distance metrics corresponding to pairs of user intentions from among the plurality of user intentions. A distance metric is computed for each pair of user intentions from among the pairs of user intentions. Furthermore, the method comprises generating a plurality of clusters based on the plurality of distance metrics. Each cluster comprises a set of user intentions. The method further comprises provisioning a VUI design recommendation based on the plurality of clusters.
Patent AU-2014292918-A1 (AU)
Title: Clinical multimodality-tools for pre-and intraoperative insulinoma diagnostics
Inventor: REINER THOMAS
IPC: A61K49/14
Filed: 2014-07-25
Abstract: A chemical compound has the general formula: Ex4-linker-Sar(
Patent AU-2014302024-A1 (AU)
Title: Computer implemented frameworks and methodologies for enabling climate change related risk analysis
Inventor: MALLON KARL
IPC: G06Q40/00
Filed: 2014-06-26
Abstract: Described herein are computer implemented frameworks and methodologies for enabling climate change related risk analysis. Aspects of the technology are especially applicable where a desire exists to understand risks in systems containing a large number of interdependent assets.
Patent AU-2014334040-A1 (AU)
Title: Cyclic thienouracil-carboxamides and use thereof
Inventor: HARTER MICHAEL
IPC: A61P11/08
Filed: 2014-10-02
Abstract: The present invention relates to new 2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6- carboxamide-derivatives ("thienouracil"-carboxamides) to methods for the production thereof, to the use thereof alone or in combinations for treating and/or preventing diseases, and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of pulmonary and cardiovascular disorders.
Patent AU-2014342232-A1 (AU)
Title: Use of monensin to regulate glycosylation of recombinant proteins
Inventor: PANDE SANDHYA
IPC: C12N5/00
Filed: 2014-10-30
Abstract: Methods of modulating high mannose glycoform content of a protein in a cell culture by contacting the cells expressing the protein of interest with monensin are provided.
Patent AU-2014345344-A1 (AU)
Title: Composition & methods of screening
Inventor: O'HARA STEPHEN PATRICK
IPC: A23L33/00
Filed: 2014-11-05
Abstract: The present invention relates to a prebiotic composition comprising a microbially produced oligosaccharide, wherein the oligosaccharide is characterised by being selective for a pre-determined probiotic bacterial strain and also capable of being produced by the pre- determined probiotic bacteria by reverse enzyme action. The present invention also relates to methods of screening a composition suitable for use as a prebiotic and methods for screening of prebiotics for incorporation into synbiotic formulations.
Patent AU-2014388298-A1 (AU)
Title: Biological fluid filters with molded frame and methods for making such filters
Inventor: LYNN DANIEL
IPC: B01D39/08
Filed: 2014-06-06
Abstract: Flexible housing filters for filtration of fluids and methods of making such filters are disclosed. The filters include a molded frame with no peripheral seal that houses a filter medium.
Patent AU-2015200176-A1 (AU)
Title: Method of assessing hydrocarbon source rock candidate
Inventor: LØSETH HELGE
IPC: G01V1/30
Filed: 2015-01-15
Abstract: A method of identifying a source rock candidate, comprising the steps of: providing seismic data for a region of the Earth; analysing the data to determine the presence of a candidate source rock by locating a region of rock where the seismic data indicates a low acoustic impedance relative to an over- and/or underlying region of rock and where the seismic amplitude decreases with increasing offset.
Patent AU-2015202660-A1 (AU)
Title: Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis
Inventor: MARTINBOROUGH ESTHER
IPC: A61K31/425
Filed: 2015-05-18
Abstract: Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1 P receptor. Methods of chiral synthesis of such compounds is provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.
Patent AU-2015213486-A1 (AU)
Title: Biomarker signature method, and apparatus and kits therefor
Inventor: BRANDON RICHARD BRUCE
IPC: C12Q1/68
Filed: 2015-02-06
Abstract: The present invention discloses methods, kits, and apparatus as well as reagents and compositions associated therewith for deriving an indicator for use in diagnosing the presence, absence or degree of at least one condition in a biological subject or in prognosing at least one condition in a biological subject. Also disclosed is a biomarker signature for use in diagnosing the presence, absence or degree of at least one condition in a biological subject or in prognosing at least one condition in a biological subject. The present invention further discloses methods, kits and apparatus, as well as reagents and compositions associated therewith, for identifying biomarkers for use in a biomarker signature.
Patent AU-2015214182-A1 (AU)
Title: Crystalline polymorphs of the free base of 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
Inventor: LI ZHE
IPC: A61K31/4439
Filed: 2015-02-05
Abstract: Disclosed are crystalline free base ansolvate forms of 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde (or Compound 1), such as the free base Form I, Form II and Material N. Also disclosed are crystalline free base solvates of 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde (or Compound 1).
Patent AU-2015216953-A1 (AU)
Title: Cover device and device for monitoring the connectors of a hose system
Inventor: SCHRORS ALEXANDER
IPC: G01M3/16
Filed: 2015-02-13
Abstract: The invention relates to a cover device for covering a hose system that can be connected to a patient and has a flat structure with a liquid sensor. The liquid sensor is arranged within a convolution of the flat structure in such a way that leaks on the connectors of the hose system can be detected by said liquid sensor, even if the hose system is concealed by the cover device.
Patent AU-2015222922-A1 (AU)
Title: Sinusoidal interpolation across missing data
Inventor: KLEIJN WILLEM BASTIAAN
IPC: G10L19/005
Filed: 2015-02-27
Abstract: Provided are methods and systems for concealing missing segments and/or discontinuities in an audio signal, thereby restoring the continuity of the signal. The methods and systems are designed for and targeted at audio signals, are based on interpolation and extrapolation operations for sinusoids, and do not rely on the assumption that the sinusoids are harmonic. The methods and systems are improvements over existing audio concealment approaches in that, among other advantages, the methods and systems facilitate asynchronous interpolation, use an interpolation procedure that corresponds to time-domain waveform interpolation if the signal is harmonic, and have a peak selection procedure that is effective for audio signals.
Patent AU-2015229210-A1 (AU)
Title: Therapeutic nanoparticles comprising a therapeutic agent and methods of making and using same
Inventor: BAGRODIA SHUBHA
IPC: A61K47/28
Filed: 2015-03-13
Abstract: The present disclosure generally relates to nanoparticles comprising a substantially hydrophobic acid and a therapeutic agent (1-(4-{[4-(dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea), or pharmaceutically acceptable salts thereof, and a polymer. Other aspects include methods of making and using such nanoparticles.
Patent AU-2015237273-A1 (AU)
Title: Beta-hydroxy beta-methylbutyrate for alleviating statin myopathy
Inventor: WINTERFIELD ROLAND W
IPC: A61K31/505
Filed: 2015-03-27
Abstract: Disclosed herein are methods and compositions for alleviating side effects of statin administration, such as myopathic or myalgic side effects, short-term memory loss, abnormal liver function, glucose intolerance, hyperglycemia, increased risk for diabetes, or cumulative trauma disorder, comprising administration of β-hydroxy β-methylbutyrate (HMB) to an individual taking a statin. Also disclosed are methods and compositions for alleviating acute rhabdomyolysis comprising administration of HMB. The disclosure further provides uses of HMB in combination with a statin to alleviate side effects of statin administration.
Patent AU-2015237464-A1 (AU)
Title: Rail and method for manufacturing same
Inventor: KIMURA TATSUMI
IPC: C22C38/46
Filed: 2015-03-24
Abstract: Provided is a rail which has reduced fluctuations in hardness as measured in the length direction of the rail and also has ensured excellent wear resistance. A rail which has a chemical composition comprising 0.60 to 1.0% of C, 0.1 to 1.5% of Si, 0.01 to 1.5% of Mn, 0.035% or less of P, 0.030% or less of S, 0.1 to 2.0% of Cr, and a remainder made up by Fe and unavoidable impurities, wherein the fluctuations in surface hardness of the rail as measured in the length direction of the rail fall within the range of ± HB15 points or smaller.
Patent AU-2015242993-A1 (AU)
Title: Composite reinforcing material and molding material
Inventor: HASEGAWA SHOJI
IPC: B29B15/08
Filed: 2015-03-19
Abstract: Provided is a composite reinforcing material excellent in mechanical strength. The composite reinforcing material comprises at least graphene-like exfoliated from a graphite-based carbon material and a reinforcing material dispersed in a base material. The graphite-based carbon material is characterized by having a rhombohedral graphite layer (3R) and a hexagonal graphite layer (2H), wherein a Rate (3R) of the rhombohedral graphite layer (3R) and the hexagonal graphite layer (2H) , based on an X-ray diffraction method, which is defined by following Equation 1 is 31% or more: Rate (3R) = P3/(P3+P4)xlOO - (Equation 1) wherein P3 is apeak intensity of a (101) plane of the rhombohedral graphite layer (3R) based on the X-ray diffraction method, and P4 is a peak intensity of a (101) plane of the hexagonal graphite layer (2H) based on the X-ray diffraction method. Fig. 20 80 - : C'+ 3-0; 4 -- 5D 20 Tensi. Strength .40 end-ng~ Modu us 0 t - -- r - -r - - -- - - SD 0 10 20 30 40 50 Rate(SR)
Patent AU-2015249188-A1 (AU)
Title: A system and method for measuring relative leg positions of an ungulate
Inventor: DOYLE JOHN CONAN
IPC: A01K29/00
Filed: 2015-10-30
Abstract: A system for measuring relative positions of a front leg and a hind leg of a standing ungulate, the system comprising a grate (70) upon which an ungulate to be measured stands which comprises a plurality of parallel bars (61) spaced a known distance apart, each bar being moveable from a free position to a displaced position in response to the weight of the ungulate when a front leg (64, 65) or a hind leg (66, 67) is placed thereon, each bar having a sensor operatively associated therewith, which sensor is responsive to and transmits data regarding the displacement of an associated bar by at least one of the front leg and the hind leg and a processor for receiving the data transmitted by each sensor, and which identifies bars which have been displaced by the ungulate and based upon the distance between the displaced bars, determining the relative front leg and hind leg positions. Fl
Patent AU-2015250686-A1 (AU)
Title: Object production
Inventor: BICKERSTAFF JOHN
IPC: G05B19/4099
Filed: 2015-04-10
Abstract: Disclosed is a method of producing an object (8), the method comprising: providing a workpiece (50) comprising a plurality of attachment features (32) for attaching the workpiece (50) to a machining fixture (40); determining a datum, the datum being dependent upon the relative positions of the attachment features (32); measuring the surface of the workpiece (50) with respect to the datum; providing the machining fixture (40); attaching, using the attachment features (32), the workpiece (50) to the machining fixture (40); providing a digital model specifying the object (8) including the attachment features (32); and, thereafter, using the measurements of the workpiece surface and the digital model, controlling machining apparatus with respect to the datum to machine the workpiece (50) so as to produce the object (8) as specified by the digital model.
Patent AU-2015283151-A1 (AU)
Title: Method for adhering substrates on cold and moist surfaces
Inventor: DIMMER JORG-ALEXANDER
IPC: C08F220/14
Filed: 2015-06-15
Abstract: The invention relates to a method and suitable adhesive material compositions for adhering a substrate on cold and moist surfaces, wherein the surface temperature is lower than the dew point temperature of the air which is in contact with the surface, and wherein the adhesive material composition contains an adhesive material polymer which is formed from specific quantities of 2-ethylhexylacrylate, monomers selected from C1 to C2 alkyl(meth)acrylates, styrene, acid monomers and optionally further monomers in the presence of molecular weight regulators.
Patent AU-2015287352-A1 (AU)
Title: Personal hazard detection system with redundant position registration and communication
Inventor: THURLOW ANDREW CHARLES
IPC: G08B21/18
Filed: 2015-07-02
Abstract: A system for monitoring the safety of personnel on a work site, by providing workers on the site with portable battery powered safety monitors equipped with alarms, sensors to detect hazardous conditions, at least two forms of geo-location and two forms of voice and data telecommunication and two CPU's sharing the computation load, each CPU equipped to monitor and reset the other in case of failure to function, with each monitor capable of serving as a node in a mesh network and relaying information concerning alarms detected including location thereof to other monitors on the mesh network.
Patent AU-2015303581-A1 (AU)
Title: Device for controlling the anesthetization of an animal to be slaughtered
Inventor: SCHIMITZEK PETER
IPC: A01K29/00
Filed: 2015-08-11
Abstract: The invention relates to a device for controlling the anesthetization of an animal to be slaughtered (1) comprising a stimulation unit (2) via which a stimulation stimulus (3) can be given to an animal to be slaughtered (1), and an image capturing unit (4) comprising an image capturing range (5). Said image capturing unit (4) is designed as a 3D-camera and one part of a surface of the animal to be slaughtered (1) can be optically detected in the image capturing range, in which pixels can be collected in the area of surface and can be provided and transmitted as pixel data, and comprising an evaluation unit (6) which is connected to the image capturing unit (5) and which collects the pixel data provided by the image capturing unit (5) and said evaluation unit can determine an active movement of the animal to be slaughtered (1) from the detected pixel data and provides and transmits the control result in the event of a determined movement of the animal to be slaughtered (1).
Patent AU-2015304883-A1 (AU)
Title: Aminopyrimidinyl compounds as JAK inhibitors
Inventor: FENSOME ANDREW
IPC: C07D487/08
Filed: 2015-08-07
Abstract: A compound compound having the structure or a pharmaceutic acceptable salt thereof: Formula (I). Also provided are methods of treatment as Janus Kinase inhibitors and pharmaceutical compositions containing the compounds of the invention and combinations with other therapeutic agents.
Patent AU-2015328337-A1 (AU)
Title: Taut inverted catenary mooring system
Inventor: HOOGEVEEN SWANIK MAAS
IPC: B63B22/04
Filed: 2015-10-06
Abstract: A Taut-Inverted-Catenary (TIC) mooring system may be implemented using only field-proven components. The mooring lines yield a positive uplift force on the anchors in all conditions. In the inverted-catenary configuration, geometric stiffness is provided by a subsurface spring buoy or distributed buoyancy elements on the line. The TIC system consists as much as possible of light-weight components, such as polyester fiber rope. Since the uplift force on the anchor is always positive, clearance between polyester rope and the seabed is provided. All geometric stiffness is provided by the spring buoy. Therefore, a ground chain between the seafloor anchor and the fiber rope is not necessary.
Patent AU-2015338717-A1 (AU)
Title: Powder formulation
Inventor: MITCHELL JAMES JOHN
IPC: A61K38/095
Filed: 2015-10-29
Abstract: Methods of reducing chemical degradant formation, such as those resulting from dimer formation in disulfide bridge-closed ring-bearing polypeptides, such as oxytocin, in a solid-state; to heat stable pharmaceutical compositions having improved physio- or chemical stability, to inhalers and dosage forms of such compositions, to methods of production of and treatment of diseases and or conditions, such as post partum hemhorrage, with such compositions.
Patent AU-2015373475-A1 (AU)
Title: Process for separation of gases with reduced maintenance costs
Inventor: PRISKE MARKUS
IPC: B01D53/22
Filed: 2015-12-22
Abstract: The invention relates to a specific process and apparatus for separation of gas mixtures with reduced maintenance costs.