baber/WOPTO huggingface dataset:
Patent NZ-503413-A (NZ)
Title: Particle compositions of lipid lowering agents
Inventor: BAERT LIEVEN
IPC: A61K38/095
Filed: 1998-10-27
Abstract: A particle consisting of a solid dispersion comprising, (a) a lipid lowering agent of formula I an N-oxide, a stereochemically isomeric form, a mixture of two or more such forms, or a pharmaceutically acceptable acid addition salt thereof, wherein A and B taken together form a bivalent radical of formula: N=CH (a), CH=N (b), CH2-CH2 (c) CH=CH (d), C(=O)-CH2- (e), CH2-C(=O)-(f), in the bivalent radicals of formula (a) and (b) the hydrogen atom may be replaced by C1-6 alkyl, in the bivalent radicals of formulae (c), (d), (e), (f), one or two hydrogen atoms may be replaced by C1-6 alkyl, R1 is hydrogen, C1-6 alkyl or halo R2 is hydrogen or halo, R3 is hydrogen, C1-8 alkyl, C3-6 cycloalkyl or C1-8 alkyl substituted with hydroxy, oxo, C3-6 cycloalkyl or aryl, Het is a heterocycle selected from the group consisting of pyridine, pyridine substituted with one or two substituents selected from C1-6 alkyl, hydroxy, C1-6 alkyloxy, trihalomethyl, amino, mono or di(C1-6 alkyl)amino or aryl, pyrimidine, pyrimidine substituted with one or two substituents selected from C1-6 alkyl, hydroxy, C1-6 alkyloxy, trihalomethyl, amino, mono or di(C1-6alkyl)amino or aryl, tetrazole, tetrazole substituted with C1-6 alkyl or aryl, triazole, triazole substituted with one or two substituents selected from C1-6 alkyl, hydroxy, C1-6 alkyloxy, trihalomethyl, amino, mono or di(C1-6 alkyl)amino, thiadiazole, thiadiazole substituted with one or two substituents selected from C1-6 alkyl, hydroxy, C1-6 alkyloxy, trihalomethyl, amino, mono or di(C1-6 alkyl)amino, oxadiazole substituted with one or two substituents selected from C1-6 alkyl, hydroxy, C1-6 alkyloxy, trihalomethyl, amino, mono or di(C1-6 alkyl)amino, imidazole, imidazole substituted with one or two substituents selected from C1-6 alkyl, hydroxy, C1-6 alkyloxy, trihalomethyl, amino, mono or di(C1-6alkyl)amino, thiazole, thiazole substituted with one or two substituents selected from C1-6 alkyl, hydroxy, C1-6 alkyloxy, trihalomethyl, amino, mono or di(C1-6 alkyl)amino, oxazole, oxazole substituted with one or two substituents selected from C1-6 alkyl, hydroxy, C1-6 alkyloxy, trihalomethyl, amino, mono or di(C1-6 alkyl)amino, aryl is phenyl or phenyl substituted with C1-6 alkyl or halo, and (b) one or more pharmaceutically acceptable water-soluble polymers. Also described is the use of the abovementioned particles in the manufacture of pharmaceutical dosage forms for treating hyperlipidemia, obesitas and atherosclerosis. Such dosage forms can be administered once daily, and in addition at any time of the day. These particles are obtained by melt-extruding a mixture comprising a lipid lowering agent and an appropriate water-soluble polymer and subsequently milling said melt-extruded mixture.
Patent NZ-509695-A (NZ)
Title: Cached chainback ram for serial Viterbi decoder
Inventor: HANSQUINE DAVID
IPC: H03M13/41
Filed: 1999-08-04
Abstract: A serial Viterbi decoder having a chainback cache is provided for use in a mobile telephone. The decoder includes a branch error metric block, an add-compare-select unit, and a chainback block including a chainback RAM, a full chainback cache and chainback controller circuitry. The chainback cache caches decision bits from previous process cycles such that full chainback operations need not always be performed. The chainback cache is configured to cache on all reads. With the chainback cache, significant savings in power consumption and processing time may be achieved with only a relatively modest increase in the amount of circuitry required. A full chainback cache need not provided. Rather, the chainback block instead includes an L+1 bit RAM, an updown counter and a shift register configured to emulate a chainback cache or an L bit shift register is employed instead of the combination of the L+1 bit RAM and updown counter. The chainback block may be configured to perform only one chainback read or several reads in each process cycle. The chainback block may be configured to perform chainback operations based on (a) through (b) reads where the cache is accessed for each read after (a) reads have been done until (b) reads have been performed or a match is obtained. The chainback block may be configured to perform chainback operations over multiple process cycles rather than only a single process cycle.
Patent NZ-510777-A (NZ)
Title: Coating compositions containing functionalised silicones
Inventor: DORGET MICHEL
IPC: C09D183/06
Filed: 1999-10-05
Abstract: A coating composition, in particular a paint comprising: (A) 3 to 30 parts of a latex consisting of organic (co)polymers having a glass transition temperature ranging between -20 DEG C and 50 DEG C; (B) 0.05 to 5 parts of an epoxyfunctionalised polyorganosiloxane emulsion; (C) and 100 parts of mineral fillers.
Patent NZ-514971-A (NZ)
Title: A direct drive coupling
Inventor: REINHOLD THEODORE WILLIAM
IPC: B02C18/08
Filed: 2001-01-24
Abstract: A direct drive coupler (14) couples an article such as a chipper disc (12) to an output shaft (13). The output shaft (13) has a keyway (20) which operatively engages a key (30) clamped in place by grub screws (33) screwed through a collar (32). The direct drive coupler (14) may be incorporated into an apparatus such as a garden refuse shredder.
Patent NZ-517040-A (NZ)
Title: Method and device for determining the hardness of products such as fruit
Inventor: CREZEE LEONARDUS PAULUS
IPC: G01N29/12
Filed: 2000-07-31
Abstract: A method for determining the hardness of a product, for instance   fruit,  during  a  measuring  cycle,  comprising: supporting the product, tapping the product with  a  tapping device at least one position of the product, as a result  of which  the  product  as  a  whole  is  set  in  its  natural vibration  and  produces  vibration  signals,  sensing   the vibration  signals with a signal sensor, and processing  the vibration signals with a signal processing device, in  which the  hardness FRi of the product is determined, and  further comprising:  sensing  the signals produced  by  the  tapping device   with   a  second  signal  sensor,  processing   the vibration  signals  with a second signal processing  device, the elastic properties of the product being determined in  a volume  range  around  the  above  at  least  one  position, determining  the hardness FIi of the product, comparing  FIi and  FRi  and  checking the comparison with  a  pre-adjusted value,  the  tapping  and  sensing with  the  second  signal sensor  being repeated when the comparison does not  satisfy the  pre-adjusted value, the hardness can be  advantageously determined,  in  particular intended for  labeling  products when selecting and subsequently sorting fruit. A device  for carrying  out  this  method can be  used  both  for  desktop applications  and  for  on-line  determinations  on  sorting machines.
Patent NZ-527206-A (NZ)
Title: Medicinal combination of a biguanide and a transporter, for example metformin and arginine
Inventor: RAPIN JEAN-ROBERT
IPC: A61K47/48
Filed: 2001-12-31
Abstract: Disclosed herein is a use of a composition consisting of a biguanide as a first medicament, and an agent for transporting the said biguanide, as a second medicament, wherein said composition comprises: (a) a therapeutically active quantity of the biguanide, in particular a N-dimethylbiguanine; and (b) a quantity of transporting agent chosen from the group consisting of arginine, putrescine, cadaverine, spermidine and spermine, for the manufacture of a medicament for the treatment of diabetes, particularly type 2 diabetes .
Patent NZ-528676-A (NZ)
Title: Use of bisphosphonates in the treatment of bone metastases associated with prostate cancer
Inventor: SEAMAN JOHN J
IPC: A61K31/00
Filed: 2002-04-30
Abstract: Use of an N-bisphosphonate in the preparation of a medicament for the treatment of osteoblastic metastases associated with prostate cancer is disclosed. The N-bisphosphonate is a compound represented by formula (I), wherein X is hydrogen, hydroxyl, amino, alkanoyl, or an amino group substituted by C1-C4 alkyl, or alkanoyl; R is hydrogen or C1-C4 alkyl and Rx is a side chain which contains an optionally substituted amino group, or a nitrogen containing heterocycle (including aromatic nitrogen-containing heterocycles), or pharmaceutically acceptable salts thereof or any hydrate thereof.
Patent NZ-536334-A (NZ)
Title: An online system for estate management
Inventor: HAZELDEN GAVIN
Filed: 2004-11-04
Abstract: A method of storing information relating to and reporting on an estate is disclosed. Data directly relating to the estate is stored and remote access is provided by at least the owner of the estate to the data of the estate allowing the owner of an estate to add or amend items relating to the estate. On the occurrence of a trigger event relating to the estate and associated with the storage of trigger event related data purporting to confirm the trigger event with the estate data, the data stored relating to that estate is reported. Report documents required to meet legal requirement are generated from stored data on the trigger event. The stored data includes a record of the will of the subject. The trigger event is the death of the estate owner, and the associated data is the storage of a death certificate copy.
Patent NZ-538126-A (NZ)
Title: Fibre optic cable where signal transmitting members have movement restricted by a surrounding layer
Inventor: BROWN GEORGE HENRY PLATT
IPC: G02B6/44
Filed: 2003-06-26
Abstract: A cable assembly that includes a plurality of flexible signal transmitting members 2 is disclosed. The cable is arranged so that the signal transmitting members 2 are surrounded by a first layer 3 that restricts movement between at least the outermost members of the bundle. An outermost thermoplastic polymer layer 4 surrounds the first layer, and has a Shore D hardness of at least 60.
Patent NZ-538722-A (NZ)
Title: 31 kDa metal enriched copper/zinc superoxide dismutase obtained from the haemolymph of the shellfish Crassostrea gigas
Inventor: SCOTTI PAUL DOUGLAS
Filed: 2001-03-27
Abstract: Disclosed is a protein readily extracted from the pacific oyster Crassostrea gigas exhibiting metal ion binding activity and can be formulated into bioremediation compositions, foodstuffs and nutraceuticals. The protein has a molecular weight of approximately 20 kDa and an amino acid sequence selected from: a) TAXNEANVNIYLHLSDDEDSNYENS (N-terminus) (SEQ ID NO:1) b) EPNAFMPGNLHHRV (SEQ ID NO:2) c) EHGXDTIGEL (SEQ ID NO:3)
Patent NZ-540502-A (NZ)
Title: Fungicidal mixtures based on a triazolopyrimidine derivative and amide compounds
Inventor: TORMO I BLASCO JORDI
Filed: 2003-11-14
Abstract: Disclosed herein are fungicidal mixtures containing a synergistically effective amount of (a) a triazolopyrimidine of formula (I), and (b) amide compounds of formula (II), wherein X1 and X2 represent halogen, nitro, cyano, alkyl, alkenyl, alkynyl, haloalkyl, haloalkenyl, haloalkynyl, alkoxy, haloalkoxy, haloalkylthio, alkylsulfinyl, or alkylsulfonyl, x represents 1, 2, 3, or 4, and y represents 1, 2, 3, 4, or 5. Also disclosed are methods for controlling destructive fungi by means of mixtures of compounds (I) and (II), agents containing said mixtures, and the use of compounds (I) and (II) for producing such mixtures.
Patent NZ-541975-A (NZ)
Title: Storage-stable and bio-stable formulations of ace inhibitors including enalapril maleate and quinapril hydrochloride, and methods for preparation thereof
Inventor: SPIREAS SPIRIDON
Filed: 2003-12-05
Abstract: Disclosed is a method of preparing a stable formulation of an ACE inhibitor which comprises the steps of: dispersing or dissolving a metal compound in an alcohol to form a metallic alcoholic dispersion; mixing said ACE inhibitor into said metallic alcoholic dispersion; and mixing until a clear solution is attained; wherein said stable formulation of an ACE inhibitor comprises less than 11% by weight of hydrolytic breakdown product after incubation at 40 deg C and 75% relative humidity for 10 days and subsequent contact with water maintained at 37 deg C for 3 hours.
Patent NZ-549510-A (NZ)
Title: Enhanced penetration of biocides
Inventor: MAYNARD NIGEL PAUL
Filed: 2006-08-28
Abstract: Disclosed is an organic substrate treatment composition including:  water;  a glycol solvent; and  a borate compound; wherein the pH of the composition is selected and controlled to maximise penetration of the borate compound into the substrate, and wherein the stoichiometric ratio of glycol to borate ion is between about 1.5 and about 2.5 to 1. Also disclosed is when the choice of glycol solvent determines the range of appropriate pH selection. Also disclosed is when the organic substrate is lignocellulosic.
Patent NZ-555114-A (NZ)
Title: A control method that guarantees that a variable-capacity compressor will be maintained above a minimum rotation
Inventor: SCHWARZ MARCOS GUILHERME
IPC: F04C29/02
Filed: 2006-04-27
Abstract: Disclosed is a control system for protection against break of the lubricating oil film in bearings of compressors. The system comprises: an electric motor (20) associated to a compressor (21), forming an assembly, the compressor having a bearing covered with a lubricating film; a microprocessor (10); an inverter (2) with a set of switches (SW1-SW6), the inverter modulates a voltage to feed the motor; a voltage observer (30) measuring the voltage at the output of the inverter; and a current observer (40) measuring the current through the set of switches. The microprocessor actuates the set of switches selectively to generate a rotation on the motor-compressor assembly, the compressor having a minimum rotation so that the lubricating film will not break. The microprocessor establishes a bearing-situation variable, the bearing-situation variable having a foreseen maximum value, and raises the rotation of the motor to a value higher than the minimum rotation according to a pre-established relation of the bearing-situation variable, to prevent the breakage of the oil film in the bearing.
Patent NZ-555911-A (NZ)
Title: Deazapurines and uses thereof
Inventor: DAUN JANE
IPC: A61P7/04
Filed: 2003-01-07
Abstract: Disclosed are compounds of formulae II and III, wherein n is 1 and R1 is Cl, or n is 0 and R1 is COOH. The compounds are intermediates useful in the preparation of deazapurine compounds which are suitable for the inhibition of the inflammatory cytokine pathway, cell proliferation or inflammation.
Patent NZ-565297-A (NZ)
Title: Programmable slicer with powered food carriage
Inventor: RUMMEL SAMUEL A
IPC: B26D5/00
Filed: 2006-06-28
Abstract: A food product slicer 10 comprises a slicer body 12, a slicer knife 14 mounted for rotation relative to the slicer body 12, a food support carriage 16 that can move back and forth past the slicer knife 14, an adjustable gauge plate for varying the slice thickness, an automated carriage drive, an encoder arrangement that provides an output tracking the position of the carriage 16 along the carriage path, and a controller connected with the carriage drive and encoder arrangement. The carriage drive comprises a linear motor 32 with a forcer and a stator, with the forcer and the stator each having a magnetic field generator. The forcer which moves along a linear path relative to the stator is linked to and moves the carriage 16. The controller includes memory for storing the carriage stroke start position, with the controller automatically identifying and storing the carriage stroke start position when the knife starts cutting the food product.
Patent NZ-579617-A (NZ)
Title: Heat exchanger having fins with fine pores for adsorbing water by capillary action
Inventor: MORIMOTO HIROYUKI
IPC: F24F1/0063
Filed: 2008-03-26
Abstract: Heat exchangers (40) which perform heat exchange between a refrigerant and air are provided with fins (45) for transferring heat. The fins (45) have fine pores, each of which sucks water in the air by capillary condensation phenomenon and has a diameter of 1-3.5nm. The fine pores are preferably distributed to have the diameters vary depending on the positions on the surfaces of the fins (45).
Patent NZ-585161-A (NZ)
Title: Fluoropolymer compositions and treated substrates
Inventor: BROWN GERALD ORONDE
IPC: C08G18/38
Filed: 2008-12-03
Abstract: Disclosed is a composition for imparting surface properties to substrates comprising an aqueous solution or dispersion of at least one polyurethane having at least one urea linkage prepared by: (i) reacting (a) at least one diisocyanate, polyisocyanate, or mixture thereof, having isocyanate groups, and (b) at least one fluorinated compound selected from the formula (I) where the substituents are as disclosed in the specification; and thereafter (ii) reacting with (c) water and (d) 0.05 to about 2.0 percent by weight of an isocyanate-reactive non-fluorinated particulate component, based on a total dry weight of the composition. Also disclosed is a method of providing water repellence, oil repellence and soil resistance to a substrate comprising contacting the substrate with the composition. Further disclosed is a substrate treated with the composition where the substrate is a fiber, yarn, fabric, fabric blend, textile, spun laced nonwoven, carpet, paper or leather of cotton, cellulose, wool, silk, rayon, nylon, aramid, acetate, acrylic, jute, sisal, sea grass, coir, polyamide, polyester, polyolefin, polyacrylonitrile, polypropylene, polyaramid, or blends thereof.
Patent NZ-587632-A (NZ)
Title: An anti-cd6 monoclonal antibody and a method thereof
Inventor: MELARKODE RAMAKRISHNAN
IPC: A61K39/395
Filed: 2008-09-04
Abstract: A monoclonal antibody that comprises a heavy chain polypeptide and a light chain polypeptide of SEQ ID NOs: 1 and 2 respectively. The mAb binds domain 1 (D1) of CD6 and inhibits T cell proliferation without interfering with ALCAM binding. The mAb can be used to treat auto-immune disorders selected from multiple sclerosis, transplant rejection, type-1 diabetes, rheumatoid arthritis, psoriasis and T-cell mediated auto-immune disorders.
Patent NZ-588457-A (NZ)
Title: Humanized anti-factor d antibodies and uses thereof
Inventor: HUANG ARTHUR J
IPC: A61P27/02
Filed: 2009-04-27
Abstract: Disclosed is an anti-Factor D antibody or an antibody functional fragment thereof. The disclosed antibody comprises a light chain variable domain and a heavy chain variable domain, wherein the light chain variable domain comprises light chain hypervariable region (HVR)-1 comprising ITSTDIDDDMN (SEQ ID NO: 30), light chain HVR-2 comprising GGNTLRP (SEQ ID NO: 35), and light chain HVR-3 comprising LQSDSLPYT (SEQ ID NO: 38), wherein the heavy chain variable domain comprises heavy chain HVR-1 comprising GYTFTNYGMN (SEQ ID NO: 39), heavy chain HVR-2 comprising WINTYTGETTYADDFKG (SEQ ID NO: 40), and heavy chain HVR-3 comprising EGGVNN (SEQ ID NO: 41), wherein the anti-Factor D antibody or antibody fragment thereof further comprises one or more of the following substitutions (a) to (e): (a) substitution of the amino acid at position 10 of SEQ ID NO: 30 with L or I; (b) substitution of the amino acid at position 11 of SEQ ID NO: 30 with A or Q; (c) substitution of the amino acid at position 3 of SEQ ID NO: 35 with S or A; (d) substitution of the amino acid at position 5 of SEQ ID NO: 41 with A or Q; or (e) substitution of the amino acid at position 6 of SEQ ID NO: 41 with A or Q, and/or the heavy chain variable domain comprises an E at position 1.
Patent NZ-605501-A (NZ)
Title: Catalyst for the decomposition of lignin, method for the preparation of alcohols and organic acids, method for the preparation of lignin-decomposition products, catalyst for the decomposition of aromatic hydrocarbons, method for releasing hydrogen ions, as well as porphyrin
Inventor: ISHIBASHI TORU
IPC: B01J31/02
Filed: 2009-08-11
Abstract: A porphyrin catalyst for degrading lignin and a catalyst for degrading an aromatic hydrocarbon (such as dioxin), each of which contains a porphyrin that is free of a metal. A solution containing an alkali compound is added to lignin, a catalyst for degrading lignin is allowed to act on the resulting lignin-alkali compound solution as needed, which is irradiated with light as needed, or a catalyst for degrading lignin is allowed to act on lignin as needed, which is irradiated with light, whereby alcohols and organic acids are separated. A degradation product generated when the alcohols and organic acids are separated is recovered, and also hydrogen ions are released. A porphyrin having a catalytic function of converting lignin into alcohols and organic acids, a porphyrin having a catalytic function of degrading a compound containing an aromatic hydrocarbon in which an oxygen atom is bound to carbon which forms a benzene ring, or a porphyrin obtained by culturing Escherichia coli that cannot express a gene ypjD (b2611) due to mutation.
Patent NZ-606235-A (NZ)
Title: Vision recognition method for produce labeling
Inventor: CRONK STEPHEN
IPC: G01B11/24
Filed: 2011-09-12
Abstract: A method of vision recognition for use with a high speed, automatic produce labelling machine is disclosed. The method includes using laser profiling to direct a sheet of light (11) transversely to the longitudinal axis of a produce feed conveyor (91). The sheet of light (11) periodically impacts the surfaces of the produce items (31, 32, 33), such as pears, and generates laser profiles of the surfaces of the produce items (31, 32, 33) being fed by the conveyor (91) to the high speed labelling machine. The laser profiles are used to generate real world (x, y) coordinates of the domes (15a, 15b, 15c) of the incoming produce items (31, 32, 33), which are passed to the labelling machine to enable the labelling machine to adjust its position so labels are applied to the dome of the produce item (31, 32, 33). Real world height (or z) coordinates may also be created and passed to the labeller.
Patent NZ-610401-A (NZ)
Title: Inhibitors of the mutant form of kit
Inventor: BUCHDUNGER ELISABETH
IPC: A61K31/502
Filed: 2004-11-17
Abstract: Use of an inhibitor selected from midostaurin for manufacturing a drug for the treatment of a KIT dependent disease in a patient, wherein said KIT dependent disease is associated with a mutant form of KIT, and wherein: (a) the mutant form of KIT associated with the KIT dependent disease is identified as D816F, D816H, D816N, V654A, and T6701, that is associated with the KIT dependent disease selected from acute myelogenous leukemia, gastrointestinal stromal tumors, seminomas and dysgerminomas; and (b) the drug comprises an effective mutant KIT inhibiting amount of midostaurin.
Patent NZ-614718-A (NZ)
Title: Use of phospho-akt as a biomarker of drug response
Inventor: LANE HEIDI ALEXANDRA
IPC: G01N33/68
Filed: 2012-03-28
Abstract: Use of phospho-Akt as a biomarker for predicting the response, such as resistance, to compounds, wherein phospho-Akt is Akt that has been phosphorylated on one or more residues, with the proviso that for Akt1, Akt2, and Akt3 the designation phospho-Akt is used to indicate phosphorylation at a site other than T308, T309 or T305 respectively, wherein the compounds are microtubule destabilizing agents of general formula (I), wherein the substituents are as described in the specification. Methods of treatment of neoplastic and autoimmune diseases with these compounds are also disclosed.
Patent NZ-621322-A (NZ)
Title: Decitabine derivative formulations
Inventor: JOSHI-HANGAL RAJASHREE
IPC: A61P35/00
Filed: 2012-08-29
Abstract: Disclosed herein are formulations of 2-deoxyguanosine-decitabine derivatives also comprising a substantially anhydrous solvent comprising about 60% to 70% propylene glycol; about 20% to 30% glycerin; and about 5% to 15% ethanol (w/w/w). Also disclosed is the use of the formulations in the manufacture of medicaments for treating one or more myelodysplastic syndromes, leukemia, or solid tumours.