baber/WOPTO huggingface dataset:
Patent DE-68919195-D1 (DE)
Inventor: HUGHES LESLIE RICHARD
IPC: C07D/
Filed: 1989-12-12
Granted: 1994-12-08
Abstract: The invention relates to quinazoline derivatives, or pharmaceutically-acceptable salts thereof, which possess anti-tumour activity; to processes for their manufacture; and to pharmaceutical compositions containing them. The invention provides a quinazoline of the formula:- <CHEM> wherein R<1> is hydrogen or amino, or alkyl or alkoxy each of up to 6 carbon atoms; or R<1> is substituted alkyl or alkoxy each of up to 3 carbon atoms; R<2> is hydrogen, alkyl, alkenyl, alkynyl, hydroxyalkyl, halogenoalkyl or cyanoalkyl each of up to 6 carbon atoms;  Ar is phenylene or heterocyclene; L is a group of the formula -CO.NH-, -NH.CO-, -CO.NR<3>-, -NR<3>.CO-, -CH=CH-, -CH2O-, -OCH2-, -CH2S-, -SCH2-, -CO.CH2-, -CH2.CO- or -CO.O-, wherein R<3> is alkyl of up to 6 carbon atoms; and Y is aryl or heteroaryl or a hydrogenated derivative thereof; or Y is a group of the formula -A-Y<1> in which A is alkylene, cycloalkylene, alkenylene or alkynylene each of up to 6 carbon atoms and Y<1> is aryl or heteroaryl or a hydrogenated derivative thereof; or a pharmaceutically-acceptable salt thereof.
Patent DE-68923169-D1 (DE)
Inventor: OHTA GENKICHI
IPC: A61K31/44
Filed: 1989-11-03
Granted: 1995-07-27
Abstract: An anti-human immunodeficiency virus composition which comprises a fluorine-containing pyridonecarboxylic acid derivative as an active ingredient and a pharmaceutically acceptable carrier therefor.
Patent DE-68924344-D1 (DE)
Inventor: JOLLEY SCOTT
IPC: C10M105/72
Filed: 1989-10-10
Granted: 1995-10-26
Abstract: A liquid composition is described which comprises (A) a major amount of a fluorine containing hydrocarbon containing one or two carbon atoms, and (B) a minor amount of a soluble organic lubricant free of acetylenic and aromatic unsaturation and comprising at least one sulfone or sulfoxide characterized by the formulae R1(R2)SO2 (I) R1(R2)SO (II)  wherein R1 and R2 are each independently hydrocarbyl groups, -R3O(O)CR4, -NR4R5 or -R3NR4R5 groups wherein R3 is a hydrocarbylene group, and R4 and R5 are each independently hydrocarbyl groups, or R1 and R2 are hydrocarbylene groups joined together to form a cyclic moiety including the sulfur atom, or R1 is a hydrocarbyl group and R2 is OR6 wherein R6 is a hydrocarbyl group. The liquid compositions exhibit excellent thermal stability and are useful particularly as refrigeration liquids in refrigerators and air-conditioners including auto, home and industrial air-conditioners.
Patent DE-69005215-D1 (DE)
Inventor: BAJC GERALD L
IPC: C09D133/06
Filed: 1990-05-21
Granted: 1994-01-27
Abstract: Low molecular weight hydroxyl-containing copolymers of monoethylenically unsaturated monomers as well as addition products of monoethylenically unsaturated monomers with a-alkylalkanemonocarboxylic acids and/or a,a-dialkylalkanemonocarboxylic acids in situ or subsequent to polymerization which can be cross-linked with isocyanate or aminoplast crosslinker are disclosed. The copolymers can be used to make fast drying high solids coatings.
Patent DE-69008850-D1 (DE)
Inventor: NOVACEK LAUREL A
IPC: A61M5/178
Filed: 1990-03-20
Granted: 1994-06-16
Abstract: This invention relates to a safety syringe needle device which has medical and industrial application. More particularly, this invention pertains to a syringe which, after being used by a person to inject medication or fluid into a patient, or in sampling or exposure to toxic materials, or the like, can be transformed by the person to withdraw the needle into the barrel of the syringe for disposal purposes, thereby eliminating needlestick injuries among such persons. A syringe comprising (a) a hollow elongated barrel means; (b) penetration means which is adapted to removably engage with an end of the barrel means; (c) plunger means adapted to fit within and move axially in the hollow barrel means; the plunger means causing a pumping action within the interior of the barrel means between the plunger means and the end of the barrel means when the plunger means is pushed into the interior of the barrel means in the direction of the end of the barrel means; and (d) engaging means at the end of the plunger means proximate to the penetration means, the engaging means being adapted to engage the end of the penetration means when the plunger means is fully inserted into the interior of the barrel means in the direction of the end of the barrel means and cause the penetrating means to part from the end of the barrel means and to be withdrawn into the interior of the barrel when the plunger means is withdrawn away from the end of the barrel means. An adapter for a syringe having a piston and a needle base fitting in the end of the syringe comprising: (a) a protrusion formed at one end of the adapter for fitting inside the hollow of a base affixed to a syringe needle; (b) releasable engagement means formed in the exterior of the adapter and being adapted to releasably engage with the interior of the needle receiving end of a syringe barrel; and an engagement means formed in the end of the adapter opposite the protrusion, said engagement means being adapted to engage with the piston end of a syringe plunger.
Patent DE-69012173-D1 (DE)
Inventor: O'NEILL GERALD J
IPC: C09K5/04
Filed: 1990-02-27
Granted: 1994-10-13
Abstract: A chlorine-free refrigerant comprised of bis (difluoromethyl) ether; CHF2OCHF2. The refrigerant may be used alone or in combination with other refrigerants. The bis (difluoromethyl) ether refrigerant is environmentally safe, non toxic, non flammable and has the desired physical, chemical and thermodynamic properties necessary for a refrigerant.
Patent DE-69015702-D1 (DE)
Inventor: JOULAIN DANIEL
IPC: A61L9/01
Filed: 1990-05-28
Granted: 1995-02-16
Abstract: Deodorant compositions containing an aldehyde chosen from acyclic and non-terpene aliphatic aldehydes, non-terpene alicyclic aldehydes, terpene aldehydes, aliphatic aldehydes substituted by an aromatic group, bifunctional aldehydes and an aldehyde chosen from aldehydes having a carbon-borne non-aromatic aldehyde-function alpha-unsaturation, aldehydes having aldehyde-function alpha-unsaturation conjugated with an aromatic cycle and aldehydes whose function is borne by an aromatic cycle. Deodorant products containing the above.
Patent DE-69020307-D1 (DE)
Inventor: SPRUIJT HERMAN
IPC: H02M3/335
Filed: 1990-05-28
Granted: 1995-07-27
Abstract: PCT No. PCT/EP90/00904 Sec. 371 Date Mar. 25, 1991 Sec. 102(e) Date Mar. 25, 1991 PCT Filed May 28, 1990 PCT Pub. No. WO90/15469 PCT Pub. Date Dec. 13, 1990.An electric converter comprising at least three reactive elements (1, 2, 3) connected in series, and a switching device comprising a switching transistor (4) and a diode (5), the switching transistor operating at a high frequency so that it becomes conductive for a fraction of each period of said frequency. The transistor (4) and the diode (5) are connected to the connection points (12, 13) between the reactive elements (1, 2, 3) so that the diode (5) is conductive only when the transistor (4) is non-conductive and so that it is non-conductive each time the transistor (4) becomes conductive. This device is used to control the electric current from a DC power supply to a load.
Patent DE-69031686-D1 (DE)
Inventor: JOHNSON WILLIAM
IPC: H03F3/26
Filed: 1990-09-19
Granted: 1997-12-11
Abstract: An output amplifier having a pair of controlled current generators each with an output impedance that is electrically connected to the other, a pair of output controllers each of which is across a corresponding one of the output impedances, and a pair of feedback impedances each connected from a corresponding one of the output controllers to a corresponding one of the controlled current generators. A differential amplifier is provided ahead of the controlled current generators with the amlifier input capacitively connected to the input of such differential amplifier. An offset adjuster is provided between the output impedances having its output connected to the capacitively connected differential amplifier input. A current feedback arrangement is provided between the output impedances and connected to the controlled current generators to be capable of altering currents generated thereby.
Patent DE-69125449-D1 (DE)
IPC: C12H1/044
Filed: 1991-10-22
Granted: 1997-05-07
Abstract: A filter aid which, in contrast to conventional aids of complicated geometric structure and random size, consists of spherical beads of well-determined particle size. By virtue of the narrower distribution of the pore size, the spherical shape makes it possible to dispense with the use of a precoating. This aid is used in brewing, using the so-called precoating technique.
Patent DE-69131047-D1 (DE)
Inventor: MARSHALL KEITH
IPC: A61P43/00
Filed: 1991-12-04
Granted: 1999-04-29
Abstract: The present invention provides for a phased-release oral dosage form comprising a plurality of H2 receptor antagonist pellets in a polymer matrix. Each phase, containing a plurality of pellets which may be optionally coated with a release delaying substance, may have different release rates, thereby providing release of the H2 antagonist over an extended duration of time.
Patent DE-69203394-D1 (DE)
Inventor: WESLER JOHN R
IPC: A23L2/42
Filed: 1992-05-28
Granted: 1995-08-17
Abstract: The present invention provides an aqueous shelf-stable beverage product comprising: water; milk solids, the milk fat content of which is at least about 15% by weight and the milk protein content of which is at least about 25% by weight based on the total weight of milk solids, the milk solids content of the beverage product being at least about 1% by weight of the beverage product; an acidic flavoring agent; a two component stabilizing system comprising a first component comprising monoglycerides and up to 10% by weight diglycerides based on the weight of the first component, and a second component comprising carrageenin or pectin or both; a buffering system comprising disodium phosphate and potassium hydroxide, said potassium hydroxide being formed by the thermal decomposition in the beverage product of potassium bicarbonate, said disodium phosphate and potassium hydroxide being present in an amount such that said shelf-stable beverage product has a pH of about 6.3 to about 6.5. The present invention also provides a method for making a shelf-stable beverage product comprising the steps of: providing a homogenized milk mixture having the two component stabilizer system; providing a buffered aqueous flavoring solution containing the acidic flavoring agent and the buffering system having a pH of from 6.8 to 7.2; mixing the homogenized milk mixture and the aqueous flavoring solution to form an intermediate liquid mixture having a pH of from 6.8 to 7.2; and heating the intermediate liquid mixture at a temperature and for a time sufficient to thermally decompose substantially all of the potassium bicarbonate to potassium hydroxide and carbon dioxide such that the pH of the intermediate mixture is from 6.3 to 6.5 and sufficient to form the shelf stable beverage product.
Patent DE-69215183-D1 (DE)
Inventor: MOULY MICHEL
IPC: H04Q1/457
Filed: 1992-09-24
Granted: 1996-12-19
Abstract: The invention makes it possible to transmit voice-frequency pairs from N predetermined frequencies over a speech-transmission telephone network in the form of a multiplex of binary speech frames having a specified format. To do this, a numerical code has been assigned to each voice frequency or to each frequency pair; the respective numerical codes are generated in response to a command to send a frequency pair; each numerical code is inserted into a numerical frame with the said format containing an identification word constituting an excluded grouping for the speech frames; and, on reception, the respective voice-frequency pairs are generated with the aid of the speech decoder, in response to the recognition of the said numerical codes, in synchronism with the frames containing one of the said identification words. <IMAGE>
Patent DE-69231686-D1 (DE)
Inventor: COSENTINO C
IPC: A01N59/00
Filed: 1992-07-14
Granted: 2001-03-15
Abstract: A stable anticorrosive consists of equilibrium of peracetic acid, acetic acid, H2O2 and an aq. diluent and has 0.001-200 ppm of added stabilisers, 0.001-10 ppm of ionic and nonionic contaminants and no added surfactants. The concn. of added stabiliser is 0.001-100 (esp. .001-10 ppm). A pref. concentrate comprises: (at equilibrium) 16-38 (esp. 23-24) wt.% of H2O2, 2.5-9 (esp. 9-10) wt.% HOAC, 1.5-6 (esp. 4-6) wt.% of HOOAc and balance purified aq. diluent.
Patent DE-69232438-D1 (DE)
Inventor: ANDERSON W FRENCH
IPC: C12N5/10
Filed: 1992-08-06
Granted: 2002-04-04
Abstract: This invention relates to the production of a retroviral vector which is capable of expressing multiple protein translation events from a single polycistronic mRNA, by using internal ribosome entry sites in place of an internal promoter.
Patent DE-69233005-D1 (DE)
Inventor: INAOKA DR
IPC: C12R1/20
Filed: 1992-07-15
Granted: 2003-05-22
Abstract: The invention concerns DNA encoding prolylendopeptidase, hybrid vectors containing such DNA, transformed hosts capable of expressing prolylendopeptidase, a process for the production of prolylendopeptidase comprising the steps of: culturing a host organism transformed with an expression vector comprising a DNA coding for prolylendopeptidase and optionally, recovering the produced prolylendopeptidase; and a process for the production of a C-terminal amidated peptide from two precursors thereof, comprising the steps of: placing the two precursors in contact with a prolylendopeptidase in a medium to convert the precursor peptides to the C-terminal amidated peptide, and recovering the resulting C-terminal amidated peptide.
Patent DE-69307578-D1 (DE)
Inventor: HOUSELSTEIN JEAN-JACQUES
IPC: F16C1/18
Filed: 1993-04-15
Granted: 1997-03-06
Abstract: The device comprises means (12) for remotely, by mechanical transmission, controlling the closure/opening of the cock which is arranged out of the ground of an external construction. This transmission comprises a metal cable (17) mounted continuously and being coupled, on the one hand, to a means (14) arranged on a manoeuvring member (13) arranged outside and out of the ground and, on the other hand, the said long cable being buried so that it couples to the valve body (18 - 23) by fitting onto the cock (19-25) of the valve so as to open/close it, the action on the manoeuvring member allowing the displacement of the cable giving rise to the rotation of the cock and its opening/closure. <IMAGE>
Patent DE-69308737-D1 (DE)
Inventor: ESTOP PASCAL
IPC: H01F6/06
Filed: 1993-11-02
Granted: 1997-04-17
Abstract: The present invention relates to a superconducting winding which can be used especially for a current limiter, including a plurality of cylindrical coils arranged coaxially, linked electrically in series and each including two windings made of superconducting material, linked electrically in parallel, arranged coaxially with respect to one another and wound in opposite directions, characterised in that in each of the coils, the windings are separated by a material having a surface resistance in the radial direction lying between 10<-5> and 10<-2>  OMEGA .m<2> at the temperature of the cryostat, the strands constituting the superconducting conductors of the windings themselves possibly also being coated with a layer of the same material. <IMAGE>
Patent DE-69310750-D1 (DE)
Inventor: INSTONE TERRY FOXALL WAY
IPC: C11D3/20
Filed: 1993-08-09
Granted: 1997-06-19
Abstract: The invention relates to surfactant containing, liquid compositions based on the magnesium salt of primary alcohol sulphates and provides and aqueous, liquid, cleaning composition having a pH from 6-8, comprising: a) 2-40% wt surfactant, said surfactant comprising primary alcohol sulphate (i) and nonionic surfactants (ii) wherein at least 50% wt of the surfactant present is primary alcohol sulphate, said surfactant comprising less than 1% on surfactant of nitrogen-containing surfactant species b) magnesium, at a Molar ratio of at least 0.3 moles Mg per mole primary alcohol sulphate.
Patent DE-69332981-D1 (DE)
Inventor: SPRIGGS K
IPC: C07K14/705
Filed: 1993-10-20
Granted: 2003-06-18
Abstract: There is disclosed a method of preparing a soluble mammalian protein by culturing a host cell transformed or transfected with an expression vector encoding a fusion protein comprising a leucine zipper domain and a heterologous mammalian protein.
Patent DE-69401658-D1 (DE)
Inventor: PLATT FRANCES
IPC: A61P31/04
Filed: 1994-05-11
Granted: 1997-03-13
Abstract: Novel N-alkyl derivatives of deoxygalactonojirimycin are provided in which said alkyl contains from 3-6 carbon atoms. These novel compounds are useful for selectively inhibiting glycolipid synthesis.
Patent DE-69402627-D1 (DE)
Inventor: JANSE VAN RENSBURG RICHARD WIL
IPC: B41J2/16
Filed: 1994-02-22
Granted: 1997-05-22
Abstract: PCT No. PCT/GB94/00348 Sec. 371 Date Dec. 20, 1994 Sec. 102(e) Date Dec. 20, 1994 PCT Filed Feb. 22, 1994 PCT Pub. No. WO94/19195 PCT Pub. Date Sep. 1, 1994An ink jet droplet generator is described, including a nozzle plate bonded to a carrier. A tuned piezo crystal and metal structure projects into an ink cavity and is mounted on a print head structure. The nozzle carrier is separated by a spacer from the print head structure and seals are provided to seal the cavity. A pillar is provided with a height slightly greater than that of the spacer between the print head structure and the nozzle carrier. The spacer is isolated from the print head structure, pillar and nozzle carrier by seals and O-ring which surrounds the pillar. In another embodiment, layers of acoustically absorbent material are provided between the spacer and each of the print head structure and nozzle element.
Patent DE-69403271-D1 (DE)
Inventor: DICESARE PAUL C
IPC: A61B17/128
Filed: 1994-03-30
Granted: 1997-06-26
Abstract: A laparoscopic ligation clip applicator for automatically applying a plurality of ligation clips includes a handle assembly (10) having an actuator (14), an elongated shaft (12) connected to the handle assembly, and an actuating mechanism (15) disposed within the shaft. The actuating mechanism includes a clamp (26) for engaging a first piece (5) of the ligation clip and a slidable driver (28) for driving a second piece (7) of the ligation clip relative to the first piece. The actuating mechanism also includes a hold (30) for preventing rearward movement of the ligation clips, and an advancer (32) for sequentially feeding the ligation clips. A slidable cam (36), operably connected to the handle assembly, actuates the clamp, the driver and the advancer. <IMAGE>
Patent DE-69407444-D1 (DE)
Inventor: AZKONA OLLACARIZQUETA MANUEL
IPC: B21D7/06
Filed: 1994-02-18
Granted: 1998-02-05
Abstract: Electrical apparatus for bending tubes (pipes), of the type of those using a transmission system consisting of a reducing-gear electric motor (gear motor) actuating, as the rotation element, a shaped shoe (block) or last, being characterised in that it is coaxial with the revolution element over which has been placed an end-of-travel cap with stationary limit-stop means which are angularly arranged so as to form a stop mechanism, during its rotation, with a peg (pin) of a rod sliding on the rotor (armature) of the apparatus which drives, by means of its movement, the displacement of the working control member (7) of the transmission system. <IMAGE>
Patent DE-69413204-D1 (DE)
Inventor: CARLSSON LENNART
IPC: A61C5/77
Filed: 1994-11-29
Granted: 1998-10-15
Abstract: PCT No. PCT/SE94/01142 Sec. 371 Date Dec. 5, 1995 Sec. 102(e) Date Dec. 5, 1995 PCT Filed Nov. 29, 1994 PCT Pub. No. WO95/15731 PCT Pub. Date Jun. 15, 1995A method and apparatus thereof for collecting control data for the production of replacement dental parts. The method includes the steps of imaging a body area and a replacement part with a single imaging device which is arranged to take a simultaneous picture of the body area from different angles during one exposure. The pictures are developed and scanned with a reading device which generates digitized data of the imaged body area and the replacement part to be applied in that area. The digitized data is transmitted to computer equipment which automatically reproduces the body area and replacement part on a screen. A computer program calculates spacial relations data of surfaces of the body area and replacement part and the data is used as control data in making and fitting the replacement part in the human body.
Patent DE-69418382-D1 (DE)
Inventor: PINOCA LEONARDO
IPC: D01F6/46
Filed: 1994-06-17
Granted: 1999-06-17
Abstract: Disclosed is a fiber for nonwoven fabrics comprising an olefin polymer material containing (by weight):   1) from 50 to 80 parts of a propylene homopolymer having an isotactic index greater than 90, or a random copolymer of propylene with ethylene and/or a C4-C8  alpha -olefin; and 2) from 20 to 50 parts of a heterophasic polymer comprising a copolymer containing from 40 to 70% of ethylene, and having an intrinsic viscosity lower than or equal to 1.5 dl/g, or said copolymer containing less than 40% of ethylene and having an intrinsic viscosity lower than or equal to 2.3 dl/g; said fiber being obtained by spinning the above olefin polymer material and then drawing it out with a draw-ratio equal to or lower than 1.8.
Patent DE-69427340-D1 (DE)
Inventor: TOMIDA YOSHINORI
IPC: H01J9/02
Filed: 1994-12-21
Granted: 2001-07-05
Abstract: A method of manufacturing an electron-emitting device having an electroconductive film including an electron-emitting region and arranged between a pair of electrodes is disclosed, said method comprising: a step of forming an electroconductive film on a substrate and a step of producing an electron-emitting region in said electroconductive film, wherein said step in forming an electroconductive film on a substrate includes a step of heating a film containing a sublimatable compound and transferring the sublimatable compound onto the substrate and a step of baking the transferred sublimatable compound. <IMAGE>
Patent DE-69431151-D1 (DE)
Inventor: JONES ROGER SPENCER
IPC: A61K31/195
Filed: 1994-03-08
Granted: 2002-09-12
Abstract: An improved process for the production of a pharmaceutical composition comprising p-hydroxyacetanilide and L-cysteine or a compound which is converted thereto in vivo comprises mixing p-hydroxyacetanilide and L-cysteine or its precursor in the solid state and then shaping the solid mixture.
Patent DE-69433175-D1 (DE)
Inventor: BAATH LARS
IPC: G01S13/88
Filed: 1994-02-03
Granted: 2003-10-30
Abstract: A method for measuring the position of at least one surface in a metallurgical process which includes the steps of providing a metallurgical melt, the metallurgical melt including at least a metal portion and a slag layer, providing a signal generator for generating signals at a plurality of frequencies over a frequency band, and providing an antenna for receiving the signals generated by the signal generator and for transmitting circularly polarized radio waves at the plurality of frequencies over the frequency band. The invention further includes the steps of disposing the antenna adjacent the metallurgical melt, transmitting the circularly polarized radio waves from the antenna toward the metallurgical melt, the circularly polarized radio waves being transmitted by the antenna at the plurality of frequencies over the frequency band, receiving reflected images of the transmitted radio waves through the antenna, the received reflected images of the transmitted radio waves having a substantially opposite circular polarization from the transmitted circularly polarized radio waves, determining a phase displacement between the transmitted radio waves and the received reflected images of the transmitted radio waves, transforming the determined phase displacement from a frequency to a time plane, and determining from the time plane transform a position of at least one surface of at least one of the metal portion and the slag layer.