baber/WOPTO huggingface dataset:
Patent NZ-548566-A (NZ)
Title: A procedure for the determination of fragmentation of DNA in animal sperm
Inventor: GOSALVEZ BERENGUER JAIME
Filed: 2005-01-26
Abstract: Disclosed is a method for the determination of DNA fragmentation in animal sperm. It particularly refers to a procedure to evaluate the integrity of the chromatin/DNA of the sperm by means of a treatment of the sample with a denaturing solution followed, optionally by a stain; a subsequent treatment with a lysis solution that does not contain a protein denaturing detergent, followed, optionally, by a stain; and an evaluation of the integrity of the chromatin/DNA. The present invention also refers to a Kit to evaluate the quality of the sperm of animals which includes a DNA denaturing solution and a lysis solution that does not contain a protein denaturing detergent.
Patent NZ-548764-A (NZ)
Title: Apparatus and methods for bone surgery
Inventor: SHERRY EUGENE
IPC: A61B17/88
Filed: 2002-11-01
Abstract: An alignment handle for use in hip replacement surgery, the alignment handle including: a body defining a distal end and a proximal end; a gauge disposed at or proximate to the proximal end; and a connector disposed at or proximate to the distal end for connection of a prosthetic acetabular cup. The gauge is adapted to indicate whether the prosthetic acetabular cup is in a predefined orientation with respect to at least a first plane in a referential system. Also disclosed is a spacer for use in hip replacement surgery, the spacer including: a first end having an opening to receive a prosthesis femoral stem with guide means on the first stem and an alignment surface defining one side of the first end. The alignment surface is adapted to engage a prosthetic acetabular cup to determine an anteversion of the cup and stem such that, in use, the cup is positioned in a predefined relationship with reference to an acetabulum of a patient.
Patent NZ-550401-A (NZ)
Title: Connector with integral piercing spike for enteral fluid delivery set
Inventor: DALY PAUL JOHN MARTIN
Filed: 2006-10-09
Abstract: A connector for use in connecting a container of liquid nutrients to an enteral feeding tube to supply the liquid nutrients to a patient includes an integrally formed spike projecting into a cavity defined by an interior surface of a body of the connector. An air passage in communication with the cavity extends through the spike to outside the connector. A filter is secured to the end of the passage outside the connector. The cavity of the connector is free of structure that both defines any portion of the liquid passage and is formed for penetrating the puncturable seal of the container.
Patent NZ-551000-A (NZ)
Title: Methods and related compositions for reduction of fat
Inventor: KOLODNEY MICHAEL S
IPC: A61Q19/06
Filed: 2005-05-19
Abstract: Disclosed is the use of a composition of at least one bile acid or a salt thereof in the manufacture of a medicament for the non-surgical removal of a localized fat accumulation in a mammal, wherein said composition is free of phosphatidylcholine. Preferred bile salts are potassium or sodium salts of deoxycholic, chendeoxycholic, 7-alpha-dehydroxylate, dihydroxy and trihydroxy-bile salts.
Patent NZ-560344-A (NZ)
Title: Modulation signals for a satellite navigation system
Inventor: PRATT ANTHONY
IPC: G01S1/00
Filed: 2004-09-01
Abstract: A method of generating a subcarrier modulation signal adapted to modulate a ranging signal of a navigation system is disclosed. The method comprises a step of multiplexing in the time domain portions of a first and second binary offset carrier (BOC) signals produce the subcarrier modulation signal. The multiplexing in the time domain comprises multiplexing in the time domain a portion of a BOC(5,1) subcarrier signal, spanning a first respective time interval, and a portion of a BOC(1,1) subcarrier signal, spanning a second respective time interval. The first respective time interval is 100 ns and the second respective time interval is 400 ns. A method of generating a navigation signal comprises the method of generating a subcarrier modulation signal as described above and then modulating the ranging signal of the navigation system using the generated subcarrier modulation signal.
Patent NZ-560805-A (NZ)
Title: Isoxazoline derivative and novel process for its preparation
Inventor: SHIN HYUN IK
IPC: C07D413/12
Filed: 2006-02-21
Abstract: The disclosure relates to an isoxazoline derivative having the cyclic carboxylic acid hemiketal moiety of formula (1) for use as caspase inhibitor, a process for preparing it, and a pharmaceutical composition comprising it, wherein the variables are as defined in the specification. These compounds are suitable for treating inflammation or preventing apoptosis includiong dementia, cerebral stroke, brain impairment due to AIDS, diabetes, gastric ulcer, cerebral injury by hepatitis virus, hepatic diseases by hepatitis virus, acute hepatitis, fulminant hepatic failure, hepatocirrhosis, sepsis, organ transplantation rejection, rheumatoid arthritis, or cardiac cell necrosis due to ischemic cardiac diseases.
Patent NZ-562874-A (NZ)
Title: A combination of 5-aminolevuline or a derivative and an iron compound for treating skin conditions
Inventor: ITO YOSHIYASU
IPC: A61K8/36
Filed: 2005-09-27
Abstract: Disclosed is the use of one or more compounds selected from 5-aminolevulinic acid, its salts, 5-aminolevulinic acid ester, and N-acyl-5-aminolevulinic acid, and also using an iron compound, for the manufacture of an external preparation for ameliorating skin diseases such as skin roughness, dry skin, wrinkles, flecks, and atopic dermatitis.
Patent NZ-563068-A (NZ)
Title: Benzimidazole-carboxamide compounds as 5-HT4 receptor agonists
Inventor: PHIZACKERLEY KIRSTEN M
IPC: A61K31/4545
Filed: 2006-05-24
Abstract: Disclosed are benzimidazole-carboxamide compounds of formula (I) wherein R1 is C3-5alkyl optionally substituted with -OH and the variables of X are disclosed within the specification. Crystalline compounds of formula (I) are also disclosed within the specification as are processes for making the said compounds. Also disclosed is the use of the compound of formula (I) for the manufacture of a medicament for the treatment of a disorder of reduced motility of the gastrointestinal tract.
Patent NZ-573216-A (NZ)
Title: Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture
Inventor: ECKHARDT MATTHIAS
IPC: C07D309/10
Filed: 2007-05-02
Abstract: Disclosed are glucopyranosyl-substituted benzonitrile derivatives represented by general formula (I) wherein R3 is cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, 1-hydroxy-cyclopropyl, 1-hydroxy-cyclobutyl, 1-hydroxy-cyclopentyl or 1-hydroxy-cyclohexyl. Also disclosed is the use of the compounds of formula (I) for treating type 1 and type 2 diabetes mellitus, complications of diabetes, metabolic acidosis or ketosis, reactive hypoglycaemia, hyperinsulinaemia, glucose metabolic disorder, insulin resistance, metabolic syndrome, dyslipidaemias of different origins, atherosclerosis and related diseases, obesity, high blood pressure, chronic heart failure, oedema and hyperuricaemia.
Patent NZ-575402-A (NZ)
Title: A magnetic clamp assembly, for formwork in concrete panels, with restraints to prevent pivoting of adapter
Inventor: SLADOJEVIC ROBERT
IPC: B25B5/00
Filed: 2007-09-04
Abstract: A magnetic clamp assembly (10) includes a magnetic clamp housing (12). The housing (12) has a front face (16) and a pair of opposes sides. A restraining arrangement comprises a restraining formation (14) projecting outwardly from each side of the housing parallel to the front face (16). An adapter (18) is mountable to the housing (12) to bear against the front face (16). The adapter (18) includes an engaging arrangement (20) which engages the restraining arrangement when the adapter (18) is mounted to the housing (12) to restrain pivoting movement of the adapter (18) relative to the housing (12).
Patent NZ-596884-A (NZ)
Title: Smart packaging for detecting microorganisms
Inventor: GUTIERREZ BARTOLOME LAURA
IPC: C12Q1/04
Filed: 2010-04-21
Abstract: 596884 Disclosed is a packaging for foods, pharmaceuticals or cosmetics, wherein the packaging comprises a packaging material and a sensor able to indicate the presence of microorganisms in the food, pharmaceutical or cosmetic without direct contact between the sensor and the food, pharmaceutical or cosmetic, the sensor being in the form of a partially polar adsorbent solid support capable of absorbing humidity, with a surface layer containing vanillin, wherein the sensor is attached to an inner side of the packaging material and is visible from outside the packaging material when in use. Also disclosed is a use of vanillin as a colorimetric reagent for visually detecting growth of microorganisms without contact between the reagent and the microorganisms.
Patent NZ-597538-A (NZ)
Title: Regioselective preparation of 2 -amino-5-trifluoromethylpyrimidine derivatives
Inventor: LINZ GUENTER
IPC: C07D239/34
Filed: 2010-08-13
Abstract: 597538 Disclosed herein is a method of making pyrimidines of formula (III) wherein X2 is a leaving group selected from the group consisting of: phenyloxy optionally substituted by 1-5 suitable substituents, heterocyclyl N-oxy optionally substituted by 1-5 suitable substituents, and heteroaryl N-oxy optionally substituted by 1-5 suitable substituents; R1 and R2 are substituents independently selected from the group consisting of hydrogen, an aromatic group and an aliphatic group, or taken together -N(R1)R2 can form a 4-11 membered aromatic or aliphatic ring; said method comprising reacting a compound of formula (I) with an amine of formula (Il) [HN(R1)R2] to form a compound of formula (III), wherein X1 is a leaving group such as chloride.
Patent NZ-601124-A (NZ)
Title: A bale cutting apparatus and method
Inventor: HERBERT MICHAEL
IPC: A01D87/12
Filed: 2010-12-07
Abstract: A bale cutting apparatus (1) for attachment to a prime mover (3) is disclosed. The apparatus comprises attachment means (2) for coupling the apparatus to a prime mover, a stop member (13), and a cutting means (4) to cut through a bale (5) containing fodder. The cutting means have an upwardly directed cutting edge (9) and is operable to retain the bale against the stop member. The cutting means are movable upwardly towards the stop member to cut through the bale such that the fodder is discharged from the bale and any bale covering materials (10) are retained between the cutting means and the stop member. The apparatus eliminates the need to separately remove any covering materials in which the fodder is wrapped and also prevents the bale covering material being discharged with the fodder. A method for cutting a bale containing fodder is also disclosed.
Patent NZ-602832-A (NZ)
Title: Fused heterocyclic hdac inhibitor compounds
Inventor: MELVIN LAWRENCE S JR
IPC: A61K31/506
Filed: 2009-07-14
Abstract: Disclosed herein are fused imidazole pyrimidine compounds of formula (I), wherein R8 is hydroxyl; Q1 and Q2 together form a cyclic moiety to make a fused ring together with the imidazole moiety and the other substituents are as defined within the specification, processes for its preparation, compositions comprising said compounds and uses thereof. Said compounds are useful as histone deacetylase (HDAC) and cyclin-dependent kinase (CDK) inhibitory activity and as such is useful in the treatment of cell proliferative disease, autosomal dominant disorder, genetic related metabolic disorder, fibrosis, autoimmune disease, diabetes, neurological disease, and Alzheimer’s disease, cystic fibrosis, injection fibrosis, endomyocardial fibrosis, pulmonary fibrosis, mediastinal fibrosis, myelofibrosis, retroperitoneal fibrosis, progressive massive fibrosis and renal fibrosis or cancer selected from the group consisting of bladder cancer, breast cancer, colon cancer, rectal cancer, endometrial cancer, kidney cancer, leukemia, lung cancer, melanoma, non-Hodgkin’s lymphoma, pancreatic cancer, prostate cancer, skin cancer and thyroid cancer. Specifically preferred examples include: N-hydroxy-4-(4-(imidazo[1,2-a]pyridin-3-yl)pyrimidin-2-ylamino)benzamide; N-hydroxy-3-(4-(imidazo[1,2-a]pyridin-3-yl)pyrimidin-2-ylamino)benzamide; N-hydroxy-5-(4-(7-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-ylamino)thiophene-2-carboxamide; N-hydroxy-5-(4-(2-methyl-6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl)pyrimidin-2-ylamino)thiophene-2-carboxamide; N-hydroxy-4-(4-(2-methyl-7-(trifluoromethyl)imidazo[1,2-b]pyridazin-3-yl)pyrimidin-2-ylamino)benzamide; N-hydroxy-4-(4-(2-methyl-7-(trifluoromethyl)imidazo[1,2-c]pyrimidin-3-yl)pyrimidin-2-ylamino)benzamide;
Patent NZ-603575-A (NZ)
Title: Tetrahydrocarboline derivative
Inventor: OHATA AKIRA
IPC: A61K31/437
Filed: 2011-07-05
Abstract: 603575 Disclosed herein are compounds of formula (I), wherein the variables are defined in the specification, and the use of said compounds in the treatment of a urinary excretion disorder and/or improving the symptoms thereof. The compounds are disclosed to have ENPP2 inhibitor activity. In one embodiment the compound is cis-4-(2-{ 9-[(2,5-dimethyl-1,3-thiazol-4-yl)methyl]-1,3,4,9-tetrahydro-2H-β-carbolin-2-yl} -2-oxoethyl)cyclohexanecarboxylic acid.
Patent NZ-609295-A (NZ)
Title: Method for treating semiconductor substrates and a semiconductor substrate
Inventor: LAUKKANEN PEKKA
IPC: H01L21/316
Filed: 2011-11-08
Abstract: Disclosed herein is a method for treating a compound semiconductor substrate, in which method in vacuum conditions a surface of an In-containing lll-As, lll-Sb or lll-P substrate is cleaned from amorphous native oxides and after that the cleaned substrate is heated to a temperature of about 250-550 °C and oxidized by introducing oxygen gas onto the surface of the substrate. The invention relates also to a compound semiconductor substrate, and the use of the substrate in a structure of a transistor such as MOSFET.
Patent NZ-611637-A (NZ)
Title: Screen connector for electrical cables and jointing assembly comprising said screen connector
Inventor: PORTAS FRANCESCO
IPC: H02G15/188
Filed: 2010-12-22
Abstract: A screen connector (10) for electrical cables and/or for jointing assemblies for electrical cables is disclosed. In high voltage electrical cables one or more conductors are covered by an insulating layer with a conductive screen coaxial over the insulation. In prior art jointing assemblies metallic shield sock surrounds a splice body held in a radially expanded state by a support core. The shield sock can be put in electrical contact with a metallic shield of the cable by the use of one or more mechanic clamps, which may be a constant force spring. Using mechanic clamps of the aforementioned type causes an increase of the time and complexity of the splicing operation. To reduce the time and complexity of the splicing operation the following connector is proposed. The connector has a conductive shield sock (11) extending about a longitudinal axis (X-X) and adapted to be coupled to a conductive screen of at least one electrical cable or to at least one jointing assembly for electrical cables. When used a part of a cable connection a shrinkable protective sleeve (12) is arranged in a radially outer position with respect to the conductive shield sock (11). At least one removable support element (13) is arranged in a radially inner position with respect to the conductive shield sock (11) to hold the conductive shield sock (11) and the shrinkable protective sleeve (12) in a radially expanded state so that a cable may be slipped inside. A jointing assembly for electrical cables is also disclosed, the jointing assembly being either in a radially expanded state or radially collapsed onto an end portion of at least one electrical cable. The jointing assembly is either a joint for connecting two electrical cables or a termination for connecting one electrical cable to a different device.
Patent NZ-612643-A (NZ)
Title: Adam6 mice
Inventor: MACDONALD LYNN
IPC: C12N15/85
Filed: 2012-02-24
Abstract: Discloses a genetically modified mouse whose genetic modifications achieve: a) ectopic placement of a nucleotide sequence that expresses an ADAM6 protein or fragment thereof that is functional in a male mouse; and b) a modified immunoglobulin heavy chain variable region locus.
Patent NZ-613543-A (NZ)
Title: Anticoagulant antidotes
Inventor: HAUEL NORBERT
IPC: C07K16/44
Filed: 2012-03-27
Abstract: Disclosed are antibodies comprising the CDRs GYTFTDYYMH, ETNPRNGGTTYNEKFKG, GTSGYDYFDY, RSSQSIVHSDGNIYLE, KVSYRFS and FQASHVPYT.
Patent NZ-615513-A (NZ)
Title: Pharmaceutical compositions comprising sorbitan esters
Inventor: HICKEY MAGALI B
IPC: C07D295/088
Filed: 2012-03-19
Abstract: Disclosed is an injectable pharmaceutical composition comprising: (a) aripiprazole lauroxil of formula A-7; (b) sorbitan laurate; (c) polysorbate 20; and (d) an aqueous vehicle, for treating disorders of the central nervous system, including anxiety or depression, bipolar disorder, autism-related irritability, schizophrenia or schizophreniform diseases.
Patent NZ-616920-A (NZ)
Title: Power generating system
Inventor: AKIHIRO TANIGUCHI
IPC: F01K7/40
Filed: 2013-10-25
Abstract: 616920 Disclosed is a geothermal fluid electrical power generating system, comprising a flasher separating a geothermal fluid supplied from a production well into steam and hot water; a steam turbine driven by being supplied with the steam separated by the flasher as a working medium; an evaporator supplied with the steam discharged from the steam turbine as a first heating medium; a first preheater supplied with the first heating medium via the evaporator; a superheater supplied with the hot water separated by the flasher as a second heating medium from the flasher; a second preheater supplied with the second heating medium via the superheater; and a medium turbine driven by being supplied with a low-boiling-point medium lower in boiling point than water as a working medium after the low-boiling-point medium is heat-exchanged in the first preheater, the second preheater, the evaporator, and the superheater in sequence, wherein, in the evaporator and the first preheater, the low-boiling-point medium and the first heating medium are heat-exchanged with each other; and wherein, in the superheater and the second preheater, the low-boiling-point medium and the second heating medium are heat-exchanged with each other..
Patent NZ-623089-A (NZ)
Title: Processes for making compounds useful as inhibitors of atr kinase
Inventor: DURRANT STEVEN JOHN
IPC: C07D413/04
Filed: 2012-09-28
Abstract: The present disclosure relates to processes and intermediates for preparing compounds useful as inhibitors of ATR kinase, such as aminopyrazine-isoxazole derivatives and related molecules. The present disclosure also relates to compounds useful as inhibitors of ATR protein kinase. The disclosure relates to pharmaceutically acceptable compositions comprising the compounds; methods of treating of various diseases, disorders, and conditions using the compounds; processes for preparing the compounds; intermediates for the preparation of the compounds; and solid forms of the compounds. The compounds have formula (I) or (II) wherein the variables are as defined herein.
Patent NZ-703441-A (NZ)
Title: System and method for treating water or wastewater
Inventor: Michael patrick anderson
IPC: C02F9/02
Filed: 2014-12-24
Abstract: The present invention relates to a treatment system, apparatus, assembly, facility, cycle and/or method for the treatment of water or wastewater, in particular, a system, apparatus, assembly, facility, cycle and/or method for treating water or wastewater received at high flowrates (including in excess of approximately 200L/min) through a series of two or more dissolved air flotation chambers.
Patent NZ-704295-A (NZ)
Title: Compositions and methods for the treatment of infections and tumors
Inventor: SHARPE ARLENE
IPC: A61K39/00
Filed: 2007-12-26
Abstract: Disclosed is the use of activated T cells and a PD-1 antagonist in the manufacture of a medicament for inducing an immune response to a tumor antigen of interest in a mammalian subject having a tumor for treating said tumor, wherein the T cells specifically recognize the tumor antigen of interest and wherein the tumor is a colon cancer. Also disclosed is the use of a Programmed Death (PD-1) antagonist and a tumor antigen or a nucleic acid encoding the tumor antigen in the manufacture of a medicament for treating a mammalian subject having colon cancer.
Patent NZ-708130-A (NZ)
Title: Methods of synthesizing a prostacyclin analog
Inventor: HERING KIRK WILLIAM
IPC: C07F7/18
Filed: 2013-12-06
Abstract: The present invention provides processes for preparing a prostacyclin analogue of Formula (I) or a pharmaceutically acceptable salt thereof, wherein R10 is a linear or branched C1-6 alkyl. The processes of the present invention comprise steps that generate improved yields and fewer byproducts than traditional methods. The processes of the present invention employ reagents (e.g., the oxidizing reagent) that are less toxic that those used in the traditional methods (e.g., oxalyl chloride). Many of the processes of the present invention generate intermediates with improved e.e. and chemical purity; thereby eliminating the need of additional chromatography steps. And, the processes of the present invention are scalable to generate commercial quantities of the final compound.
Patent NZ-719158-A (NZ)
Title: Apparatuses and methods for controlling heat for rapid thermal processing
Inventor: KULPRATHIPANJA SATHIT
IPC: F28F7/00
Filed: 2012-09-14
Abstract: Disclosed is a method for controlling heat for rapid thermal processing of carbonaceous biomass material or wood to produce charcoal. The method for processing a moisture-containing carbonaceous feedstock comprises contacting the moisture-containing carbonaceous feedstock with heated air to form a reduced-moisture carbonaceous feedstock. The reduced-moisture carbonaceous feedstock is pyrolyzed to form char; and combusting the char and transferring a portion of the combustion heat to an air stream to form the heated air.