baber/WOPTO huggingface dataset:
Patent NZ-592330-A (NZ)
Title: New retinoid derivatives endowed with cytotoxic and/or antiangiogenic properties
Inventor: CABRI WALTER
IPC: C07C59/64
Filed: 2009-12-21
Abstract: 592330 Disclosed are 3-adamantan-1-yl-4'-((E)-2-carboxy-vinyl)-biphenyl / (E)-3-(3'-adamantan-1-yl-biphenyl-4-yl)-acrylic acid derivatives as represented by the general formula I, wherein R1 is H, O(CO)OR4, NR4R5, CN, alkyl, cycloalkyl or heterocycloalkyl; wherein alkyl, cycloalkyl and heterocycloalkyl are optionally substituted once or more with alkyl, (CH2)nCOR3, O(CO)OR4, OH or NR4R5; n is 0 or 1; R3 is OH, amino, alkyl-amino or benzyloxy; R4 and R5 are independently H, alkyl, or R4 and R5 taken together with the nitrogen atom to which they are attached form a heterocycloalkyl group, or NR4R5 form a nitro group; R2 is absent or is alkylene, hydroxyalkylene, aminocarbonylalkylene, alkenylene, cycloalkylene, heterocycloalkylene, -(OCH2CH2)m-O-, branched or linear polyaminoalkylene, phenyloxy optionally substituted with nitro; m is an integer comprised between 1 and 4; A is CH2-, -CO-, -CH2-(CO)-, -NH(CO)- or -[CO-(CHR6)-NH]w-; R6 is the side chain of a natural amino acid radical; w is 1; their tautomers, their geometrical isomers, their optically active forms, as well as their pharmaceutically acceptable salts, hydrate or solvate thereof; with the proviso that R1-R2-A does not represent alkyl or alkyl-CO. Representative compounds include (S)-2-amino-3-methyl-butyric acid 3-adamantan-1-yl-4'-((E)-2-carboxy-vinyl)-biphenyl-4-yl ester hydrochloride, (E)-3-(3'-adamantan-1-yl-4'-{ 2-[2-(2-carboxymethoxy-ethoxy)-ethoxy]-acetoxy} -biphenyl-4-yl)-acrylic acid, 4-morpholin-4-yl-butyric acid 3-adamantan-1-yl-4'-((E)-2-carboxy-vinyl)-biphenyl-4-yl ester hydrochloride, 4-(4-methyl-piperazin-1-yl)-butyric acid 3-adamantan-1-yl-4'-((E)-2-carboxy-vinyl)-biphenyl-4-yl ester dihydrochloride, 1-amino-cyclopropanecarboxylic acid 3-adamantan-1-yl-4'-((E)-2-carboxy-vinyl)biphenyl-4-yl ester and (E)-3-(3'-adamantan-1-yl-4'-cyanomethoxybiphenyl-4-yl)-acrylic acid. Further disclosed is a pharmaceutical composition comprising a compound of formula I as defined above as active ingredient and at least one pharmaceutically acceptable excipient and/or diluent, for treating arthritic conditions, tumours, metastatic cancer, diabetic retinopathy, psoriasis, chronic inflammatory diseases or atherosclerosis.
Patent NZ-594137-A (NZ)
Title: Telecommunications jack with capacitive crosstalk compensation in circuit board
Inventor: HAMMOND BERNARD JR
IPC: H01R24/58
Filed: 2007-04-10
Abstract: Disclosed is a telecommunications jack (120) with crosstalk compensation for use in a twisted pair system. The telecommunications jack (120) is comprised of a housing (122) defining a port (128) for receiving a plug; a plurality of contact springs, a plurality of wire termination contacts (IDC1-IDC8), a circuit board (132) and a crosstalk compensation arrangement. The contact springs are adapted to make electrical contact with the plug when the plug is inserted into the port (128) of the housing (122). The wire termination contacts (IDC1-IDC8) are provided for terminating wires into the jack (120). The circuit board (132) includes conductive tracks that electrically connect the contact springs to the wire termination contacts (IDC1-IDC8). The crosstalk compensation arrangement provides crosstalk compensation between selected tracks of the circuit board (132). The crosstalk compensation arrangement includes, at a zone of compensation, a capacitive coupling comprised of opposing first and second capacitor plates and also generally parallel interdigitated capacitor fingers. The circuit board (132) includes first (140) and second (not shown) conductive layers separated by a dielectric layer and also a third conductive layer (144). The first capacitor plate is provided at the first conductive layer (140) and the second capacitor plate is provided at the second conductive layer (not shown). The capacitor fingers are provided at the third conductive layer (144).
Patent NZ-594428-A (NZ)
Title: Method for improving the sensory properties and resistance of food and drink products to micro-organisms
Inventor: KNIKKER DIRK ALEXANDER
IPC: A23B4/02
Filed: 2010-02-22
Abstract: 594428 Disclosed is a method for improving sensory properties and resistance of food and drink products to micro-organisms wherein the product is contacted with a composition comprising alkali metal salts having, as anions, propionate and a co-anion selected from acetate and combinations of lactate and acetate, and, as cations, potassium and hydrogen, wherein the weight-based ratio of lactate/propionate is in the range of 0 to 20 and the weight-based ratio of acetate/propionate is in the range of 0.05 to 3.5. Also disclosed is an aqueous solution comprising 3 to 10 wt% propionate, 2 to 8 wt% acetate and 15 to 60 wt% lactate, and a sodium/potassium ratio between 0 to 0.4 wt% whereby the potassium concentration is in the order of 10 to 20 wt%. Additionally a composition comprising, as anions, propionate and a co-anion selected from acetate and combinations of lactate and acetate, and, as cations, potassium and hydrogen, wherein the weight-based ratio of lactate/propionate is in the range of 0 to 20 and the weight-based ratio of acetate/propionate is in the range of 0.05 to 3.5.
Patent NZ-595307-A (NZ)
Title: Atropisomers of 2-purinyl-3-tolyl-quinazolinone derivatives and methods of use
Inventor: EVARTS JERRY B
IPC: A61K31/517
Filed: 2010-03-24
Abstract: ABSTRACT - 595307 The disclosure relates to an optically active composition comprising an atropisomer of formula 1(S) or a pharmaceutically acceptable salt or solvate thereof; wherein the atropisomer of formula 1(S) or a pharmaceutically acceptable salt or solvate thereof is present in excess of its corresponding enantiomer or a pharmaceutically acceptable salt or solvate thereof. Said optically active composition is suitable for the treatment of a condition selected from the group consisting of allergic rhinitis, asthma, atopic dermatitis, chronic obstructive pulmonary disease (COPD), multiple sclerosis (MS), rheumatoid arthritis (RA), and diabetes.
Patent NZ-596185-A (NZ)
Title: Imidazopyrazines for use as kinase inhibitors
Inventor: PASTOR FERNANDEZ JOAQUIN
IPC: A61P37/00
Filed: 2010-04-16
Abstract: There is provided Imidazo[1,2-a]pyrazine of formula (I), wherein R1, R2, R3, R4 and R5 have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. a PI3-K and/or mTOR) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease.
Patent NZ-600439-A (NZ)
Title: Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders
Inventor: DARTEIL RAPHAEL
IPC: A61K31/192
Filed: 2010-11-26
Abstract: Provided herein are 1,3-diphenylprop-2-en-1-one derivatives and pharmaceutical compositions comprising the same for treating liver disorders, in particular those requiring the reduction of plasma level of biochemical markers such as aminotransferases. The 1,3-diphenylprop-2-en-1-one derivatives of General Formula (I) have hepatoprotective properties and can be used in methods for treating liver disorders involving the pathological disruption, inflammation, degeneration, and/or proliferation of liver cells, such as liver fibrosis or fatty liver disease. In one embodiment the compound is 1-[4-methylthiophenyl]-3-[3,5-dimethyl-4-carboxydimethylmethyloxyphenyl]prop-2-en-1-one.
Patent NZ-609422-A (NZ)
Title: Baking pan with a detachable lid or base that is a push fit with the walls of the pan via a flexible seal
Inventor: WILKINSON IAN
IPC: A21B3/18
Filed: 2011-08-31
Abstract: A baking pan (100) is disclosed comprising a body (200) and a detachable part (300). The body (200) comprises at least one side wall (214) defining a first opening. The detachable (300) part comprises a rigid portion (310) that is able to be arranged to close the first opening. A flexible seal (400) is located between the rigid portion (310) and side wall (214) of the base when the detachable part (300) closes the opening. The detachable part (300) may be a removable base or lid and the push fit arrangement prevents leakage from the pan (100).
Patent NZ-610030-A (NZ)
Title: Ostomy pouch with filtering system
Inventor: LESKO MARC
IPC: A61F5/445
Filed: 2011-09-30
Abstract: Disclosed is an ostomy appliance (10) comprising a pouch (18) including a filter (22). Present ostomy pouches with filters suffer from leakage, clogging and insufficient deodorisation. The ostomy appliance (10) comprises two opposing panels (12, 14). The panels (12, 14) are at least partly sealed to one another along their peripheries. The panels (12, 14) form a pouch (18) which captures body waste. One of the opposing panels (14) includes a stomal opening (20) for positioning around a stoma, so that body waste excreted through the stoma is captured in the pouch (18). The pouch (18) comprises a filter (22) for deodorisation of odorous gas from the body waste and an opening for emitting the deodorised gas to the atmosphere. A pleated centre panel (28) is located between the two opposing panels (12, 14) and at least partly covers the filter (22) for protection. The centre panel (28) further deters ballooning of the pouch (18) from gas build up in the pouch (18).
Patent NZ-617259-A (NZ)
Title: Fuel nozzle
Inventor: MEYER ULRICH
IPC: F17C5/02
Filed: 2013-11-01
Abstract: Disclosed is a filling nozzle for dispensing a liquid such as urea solution into a tank (16) of a motor vehicle. The filling nozzle includes safety means to ensure that the filling nozzle delivers the correct fuel to a vehicle fuel tank. The filling nozzle includes a main valve (5). A safety valve (7) is arranged downstream from the main valve (5). The safety valve (7) can be moved from a closed position to an open position by means of an opening movement directed in the upstream direction. A safety device (11) comprising a sliding sleeve has an operative connection with the safety valve (7). The operative connection between the safety device (11) and safety valve (7) is realised magnetically (10, 13). The safety device (11) is also designed to detect the insertion of the filling nozzle into a tank (16) provided for the corresponding liquid. The safety device (11) effects the movement of the safety valve (7) from the closed position into the open position when the filling nozzle is inserted into a tank (16) for the corresponding liquid.
Patent NZ-617593-A (NZ)
Title: Media insertion system
Inventor: PATTEN CHRISTOPHER JOHN
IPC: H04N21/81
Filed: 2010-08-02
Abstract: A method of outputting an audiovisual substitutional media item within a media output stream at a media output device is disclosed. The media output stream comprises a video stream and an audio stream, and the media output stream includes a splice-in point. The audio content of the media output stream is decoded from encoded audio data and, if the encoded audio data for the media output stream immediately before the splice-in point arrives too late to be output before the audio content of the substitutional media item from the splice-in point, outputting dummy audio content prior to the splice-in point instead of the audio content of the media output stream. A method of outputting an audiovisual substitutional media item within a media output stream at a media output device is disclosed. The media output stream comprises a video stream and an audio stream, and the media output stream includes a splice-in point and a splice-out point. The method comprises outputting dummy audio content subsequent to the audio content of the substitutional media item if the output of the audio content of the substitutional media item occurs before the splice-out point.
Patent NZ-617710-A (NZ)
Title: Device for extracting solid material on the bed of a body of water, and associated method
Inventor: ESPINASSE PHILIPPE FRANCOIS
IPC: E21C50/00
Filed: 2012-04-27
Abstract: Disclosed is a device (10) and method for extraction of solid material on the bed (12) of a body of water (14). The disclosure notes that current devices which involve the passage of solid material through a pump causes premature wear and tear of pump components. The present device (10) avoids material contacting internal components minimising wear and tear of the components. The device (10) comprises an assembly (22), riser (48), pump (90), separator (42), upstream hose (40) and intermediate pipe (44). The assembly (22) collects material on the bed (12) of the body of water (14). The riser (48) lifts the solid material up towards a floating surface facility (26). The pump (90) which pumps a liquid lifts the solid material collected by the collection assembly (22) in the riser (48) towards the surface facility (26). The pump (90) has an intake inlet and delivery outlet (100). The separator (42) processes the collection stream received from the collection assembly (22) to form a stream having a high content of solid material and a stream having a low content of solid material. The separator (42) includes an injection inlet (64) for injecting the collection stream and at least one lower discharge outlet (68) for discharging the stream with high content of solid material. The upstream flexible hose (40) connects the collection assembly (22) to the separator (42). The intermediate pipe (44) connects the or each discharge outlet (68) for discharging the stream with high content of solid material and a lower section of the riser (48). The delivery outlet (100) of the pump (90) is tapped into the lower section (109) of the riser (48) or into the intermediate pipe (44).
Patent NZ-627419-A (NZ)
Title: Juice extraction module for juicer
Inventor: KIM JONG BOO
IPC: B30B9/14
Filed: 2013-10-30
Abstract: A juicer for shredding, pressing or crushing fruits, vegetables, leaves or roots is described. The juicer is designed such that fruits do not need to be chopped up before being disintegrated or homogenised. The juicer comprises a container (100) having a juice outlet (101); a sieve, grill or net (200) positioned inside the container (100); a screw (300) for extracting the juice of a material by being positioned inside the net (200). The screw or worm is frusto-conical in shape, narrowing in an upward direction and including helical fins or blades that become more closely spaced in a downward direction. The screw also becomes closer to the wall of the juicer in a downward direction. The juicer also has a crushing process part (600) which is connected to the slot (410), wherein the crushing process part (600) is recessed on the lower side of the cover (400) so as to accommodate the crushing part (500) therein.
Patent NZ-702728-A (NZ)
Title: Uv-blocking silicone hydrogel composition and silicone hydrogel contact lens containing thereof
Inventor: YU-CHIN LAI
IPC: G02C7/04
Filed: 2014-12-05
Abstract: The present disclosure provides a UV-blocking silicone hydrogel composition including a hydrophilic silicone macromer, a UV-blocking monomer, a first hydrophilic monomer, a crosslinker and a polymerization initiator. The hydrophilic silicone macromer has a general formula: V-L-S-(L’-V’)x, wherein V and V’ are independently ethylenically-based polymerizable groups, L and L’ are independently a covalent bond or a linkage group, S is a siloxane group having a chemical structure such as Structure 1 or Structure 2, and x is 0 or 1. A silicone contact lens containing the UV-blocking silicone hydrogel composition is also provided herein.
Patent NZ-728460-A (NZ)
Title: Compositions comprising honey, a preservative and an aqueous carrier and methods of use
Inventor: MOLONEY ANTHONY PETER
IPC: A61P31/00
Filed: 2015-07-20
Abstract: The present invention provides a composition comprising honey, a preservative selected from the group consisting of benzoic acid or a pharmaceutically acceptable salt thereof, and an aqueous carrier, wherein the honey is present in an amount in the range of from 2 to 50% w/w. Uses of the compositions of the invention for the management, treatment or prevention of a respiratory, ophthalmic, ear or vaginal condition in a subject, and for wound management are also described.
Patent NZ-743686-A (NZ)
Title: Methods for forming 3d image data and associated apparatuses
Inventor: GALLAGHER ANTHONY
IPC: G01V3/17
Filed: 2016-11-15
Abstract: A method for forming 3D image data representative of the subsurface of infrastructure located in the vicinity of a moving vehicle. The method includes: rotating a directional antenna, mounted to the moving vehicle, about an antenna rotation axis; performing, using the directional antenna whilst it is rotated about the antenna rotation axis, a plurality of collection cycles in which the directional antenna emits RF energy and receives reflected RF energy; collecting, during each of the plurality of collection cycles performed by the directional antenna: (i) radar data representative of reflected RF energy received by the directional antenna during the collection cycle; (ii) angular position data representative of an angular position of the directional antenna about the antenna rotation axis during the collection cycle; and (iii) translational position data regarding a translational position of the directional antenna during the collection cycle; processing the radar data, the angular position data and the translational position data collected during each of the plurality of collection cycles to form 3D image data representative of the subsurface of infrastructure located in the vicinity of the moving vehicle.
Patent NZ-750355-A (NZ)
Title: Insulin analogs
Inventor: MENTING JOHN GERBRANDT TASMAN
IPC: C07K14/62
Filed: 2017-07-21
Abstract: The present invention relates to insulin analogs, particularly insulin analogs having shortened B chains. The present invention also relates to the crystal structure of insulin from the venom of cone snails and to methods of using the crystal and related structural information to screen for and design insulin analogs that interact with or modulate the insulin receptor. The present invention also relates to therapeutic and prophylactic methods using insulin analogs. In particular, the invention relates to insulin analogs which are monomeric, fast-acting, and comprise a human insulin B chain which further comprises amino acids substitutions of H10D, H10E, or H10Q, and G20Y.
Patent NZ-753163-A (NZ)
Title: Liquid allergen compositions and methods for making the same
Inventor: DOMBKOWSKI ASHLEY
IPC: A23L33/00
Filed: 2017-11-21
Abstract: Liquid mixed allergen compositions of 16 different protein allergens wherein said protein allergens have a combined fat content above 6% are provided. Also provided are methods of making liquid mixed protein allergen compositions wherein said protein allergens have a combined fat content above 6% and administering a liquid mixed allergen composition to a subject.
Patent NZ-759846-A (NZ)
Title: Deep learning-based splice site classification
Inventor: MCRAE JEREMY FRANCIS
IPC: G07D11/18
Filed: 2018-10-15
Abstract: In order to use deep learning-based techniques for training deep convolutional neural networks, a computer-implemented method to predict likelihood of splice sites in pre-mRNA genomic sequences is proposed and includes: training an atrous convolutional neural network, ACNN, on training examples of pre-mRNA nucleotide sequences, including at least 50000 training examples of donor splice sites, at least 50000 training examples of acceptor splice sites, and at least 100000 training examples of non-splicing sites, wherein the training includes inputting one-hot encoded training examples of the nucleotide sequences, wherein each nucleotide sequence comprises at least 401 nucleotides, with at least one target nucleotide and context of at least 200 flanking nucleotides on each side, upstream and downstream of the target nucleotide; and wherein the training further includes adjusting, by backward propagation, parameters of filters in the ACNN to predict scores for likelihood that each target nucleotide in the nucleotide sequence is a donor splice site, an acceptor splice site, or a non-splicing site; whereby the trained ACNN is configured to accept as input a pre-mRNA nucleotide sequence, of at least 401 nucleotides that is one-hot encoded and that includes at least one target nucleotide and context of at least 200 flanking nucleotides on each side, and to score the likelihood that the target nucleotide is a donor splice site, an acceptor splice site, or a non-splicing site.
Patent NZ-784708-A (NZ)
Title: Density flow meter for pharmaceutical formulation dosing
Inventor: WADDINGTON DAVID
IPC: B67C3/28
Filed: 2020-07-29
Abstract: Provided are systems and method for dosing a pharmaceutical formulation. These methods and systems can displace the pharmaceutical formulation through a density flow meter, wherein the density flow meter is configured to measure a density of the pharmaceutical formulation. Next, the pharmaceutical formulation can be dosed into preformed molds and the dosing process can be stopped when the density of the pharmaceutical formulation measured by the density flow meter is below a predetermined threshold. The invention addresses issues of incorrect dosing amount due to ingress of air.
Patent RO-83484-A (RO)
Inventor: LOCATELLI JEAN L
IPC: C08G59/06
Filed: 1981-08-26
Abstract: Glycidyl polyethers of polyphenols are prepared by reacting at least one alkali metal salt of a polyphenol with at least one 1-halogeno-2,3-epoxyalkane, in an anhydrous and essentially aprotic reaction medium, and in the presence of a catalytically effective amount of a catalyst which comprises a cross-linked organic polymeric support, said support having a plurality of catalytically active functional groups covalently coupled thereto, the free valence of said functional groups having the structural formula:   <IMAGE>   The subject process is admirably suited, for example, for the preparation of epoxy resins from the disodium salt of bisphenol A and epichlorohydrin.
Patent RO-84703-A (RO)
Inventor: DUBOST DOMINIQUE
IPC: F16B37/04
Filed: 1982-10-18
Abstract: 1. Fastening device with a retained nut, of the type constituted by a nut (1, 11) slidingly mounted on a support (3, 13) which can be attached in the orifice (7) of a panel (P) or the like, such as for example a metal sheet, to allow the nut (1, 11) to be retained on the panel (P), characterized in that the said support (3, 13) has at least two legs (4, 14) extending right through the nut body (1, 11) by passing through orifices, slots or the like (2, 12) provided in the said nut body (1, 11) substantially along its axis X, X'.
Patent RU-94024145-A (RU)
Inventor: GODIN S M
IPC: A61B5/02
Filed: 1994-07-13
Abstract: FIELD: biomedical technology. SUBSTANCE: method involves initial preparing person to correction, measuring parameters, their analyzing and comparing with possible adaptational reactions, followed by controlling and correcting factors are formed depending on changed person's state; then person is isolated from disturbing physical factors and state of mental sedation is attained, herewith photopletizmographic signals, characterizing bioenergic condition of person, as well as heart rate, breathing rate, saturation level of arterial hemoglobin by oxygen, and blood filling of tissues, are measured. As a result, potential energy store of organism, bioenergic balance factor and type of stable bioenergic reaction, as well as type of adaptational reaction of organism, level of reactivity and balanced homeostasis are defined. EFFECT: higher efficiency during examination of bioenergic state of organism. 1 dwg