baber/WOPTO huggingface dataset:
Patent NZ-266359-A (NZ)
Title: Use of tiazofurin and ribavirin to prepare medicament for treatment of neoplastic disease
Inventor: WEBER GEORGE
IPC: A61K31/70
Filed: 1994-05-05
Abstract: The present invention relates to the treatment of neoplastic disease in warm blooded animals using the sequential administration of tiazofurin and ribavirin. Tiazofurin is administered first in a high dose in order to facilitate a sharp decrease in IMP DH activity. These gains are consolidated by the continual administration of tiazofurin until the hematological levels have stabilized and remission is achieved. Once the patient is in remission, ribavirin is administered in steadily tapering dosages until the minimum dosage that will retain the beneficial effect of the tiazofurin is achieved. The IMP DH activity, GTP concentration, and hematological data is continually monitored throughout the treatment and dosages adjusted.
Patent NZ-266400-A (NZ)
Title: Casting method for eutectic alloy system: adding particulate material to molten stream to extract heat at point of casting
Inventor: DOLMAN KEVIN FRANCIS
IPC: B22D27/04
Filed: 1994-05-20
Abstract: PCT No. PCT/AU94/00264 Sec. 371 Date Jun. 18, 1996 Sec. 102(e) Date Jun. 18, 1996 PCT Filed May 20, 1994 PCT Pub. No. WO94/27763 PCT Pub. Date Dec. 8, 1994The present invention relates to eutectic alloy systems, such as white irons, in which a primary phase grows out of the melt when the melt is cooled below the liquidus temperature and comprises pouring the molten metal alloy at a temperature at or above the liquidus in a stream into a casting mould to form a casting and introducing a particulate material into the stream of molten metal to extract heat from the molten metal alloy to undercool the molten metal alloy from the pour temperature into the primary phase solidification range between the liquidus and the solidus temperatures of the alloy and thereby initiate primary phase nucleation and restrict primary phase growth. The primary function of the particulate material is to act as a heat sink but the particulate material may at least partially dissolve in the melt and may act as a seeding agent for the primary phase. The invention is described with particular reference to high chromium hypereutectic white irons.
Patent NZ-270659-A (NZ)
Title: Mammalian protein which binds to a gst-fkbp-rapamycin complex, dna therefor and diagnostic compositions
Inventor: MOLNAR-KIMBER KATHERINE LU
IPC: A61K48/00
Filed: 1995-03-08
Abstract: This invention comprises novel Rapamycin-FKBP12 binding proteins of mammalian origin for identification, design and synthesis of immunomodulatory, anti-restenosis or anti-tumor agents, as well as fragments of the proteins and the DNA, cDNA, antisense RNA and DNA segments corresponding to the proteins. This invention also comprises methods for isolating the proteins and therapeutic uses related to the proteins.
Patent NZ-273367-A (NZ)
Title: Preparation of 3<beta>-hydroxy (or lower acyloxy)-16,17-ene-17-(2-pyridyl)-substituted steroids using a palladium complex catalysed cross coupling reaction
Inventor: POTTER GERARD ANDREW
IPC: C07J43/00
Filed: 1994-09-22
Abstract: A method of preparing a 3 beta -hydroxy- or 3 beta -(lower acyloxy) 16,17-ene-17-(3-pyridyl)-substituted steroid, wherein the 3 beta -(lower acyloxy) group of the steroid has from 2 to 4 carbon atoms, which comprises subjecting a 3 beta -hydroxy-16,17-ene-17-iodo or -bromo steroid to a palladium complex-catalysed cross-coupling reaction with a (3-pyridyl)-substituted borane in which the pyridine ring is substituted at the 5-position by an alkyl group of 1 to 4 carbon atoms or is unsubstituted thereat, in a proportion of at least 1.0 equivalent of borane per equivalent of steroid, in an organic liquid which is a solvent for the 3 beta -hydroxy steroidal reaction product, and optionally esterifying the resulting 3 beta -hydroxy steroidal reaction product with an esterifying agent effective to replace the hydroxy group by a said lower acyloxy group, which method comprises (a) carrying out the reaction with not more than 1.2 equivalents of borane per equivalent of steroid or (b) crystallising the product of the cross-coupling reaction from a mixture of acetonitrile and methanol.
Patent NZ-275314-A (NZ)
Title: Imidazo[1,5-a]quinoline derivatives, preparation and medicaments
Inventor: JACOBSEN ERIC JOHN
IPC: C07D471/04
Filed: 1994-10-27
Abstract: PCT No. PCT/US94/12197 Sec. 371 Date May 13, 1996 Sec. 102(e) Date May 13, 1996 PCT Filed Oct. 27, 1994 PCT Pub. No. WO95/14020 PCT Pub. Date May 26, 1995Imidazo[1,5-a]quinolines of formula (I) which are useful pharmaceutical agents for the treatment of anxiety, sleep disorders, panic states, convulsions and muscle disorders.    <IMAGE>  (I)
Patent NZ-276935-A (NZ)
Title: Microemulsion cleaning composition, anionic and/or nonionic surfactant, hydrocarbon or perfume, and grease release agent
Inventor: MISSELYN ANNE MARIE
IPC: C11D1/83
Filed: 1994-11-18
Abstract: An improvement is described in microemulsion compositions which contain an anionic detergent, a nonionic surfactant, a grease release agent, a hydrocarbon ingredient, and water which comprises the use of a water-insoluble odoriferous perfume as the essential hydrocarbon ingredient in a proportion sufficient to form either a dilute o/w microemulsion composition containing, by weight, 1% to 20% of an anionic detergent, 6 to 50% of a cosurfactant, 1% to 10% of a grease release agent, 0.4% to 10% of perfume and the balance being water as well as all purpose hard surface cleaning composition or light duty liquid detergent compositions which contain a grease release agent.
Patent NZ-285435-A (NZ)
Title: Medicated wipe impregnated with a lipophilic emollient and an active ingredient
Inventor: GOODMAN MICHAEL
IPC: A61K9/70
Filed: 1995-05-17
Abstract: A wipe, comprising an absorbent woven or non-woven fabric, cloth or tissue substrate, impregnated with a pharmaceutically active agent, wherein the agent is a substance effective in stimulating melanocytes to produce melanin and/or is effective in a topical treatment of a skin condition in combination with electromagnetic radiation falling in the range of 220-700nm.
Patent NZ-304150-A (NZ)
Title: Substance delivery device
Inventor: JELLIE HUGH PHILIP
IPC: A61M31/00
Filed: 1996-03-25
Abstract: An implantable drug delivery device, intended for implantation in animals, includes a body 1 with retention arms 3.  The arms are flexible along their length and capable of contacting the surfaces of the body cavity into which it is inserted.  The flexibility of the arms is such that the arms can withstand compressive forces without the arms breaking, or damaging the walls of the body cavity.  The body may contain reservoirs from which a drug or other substance is pumped under microprocessor control.  Divisional filed as 500444
Patent NZ-332192-A (NZ)
Title: Patch containing isosorbide dinitrate comprising a flexible substrate having a pressure sensitive adhesive layer containing an acrylic and polyvinyl acetate based adhesive a plasticising component and isosorbide dinitrate
Inventor: HIDAKA OSAFUMI
IPC: A61K31/34
Filed: 1998-01-06
Abstract: The present invention relates to an isosorbide dinitrate-containing patch, in which an adhesive layer comprising an adhesive composition is formed on a flexible support, and the adhesive composition consists of an acrylic-based adhesive (A), a polyvinyl acetate-based adhesive (B), a plasticizing component (C) and isosorbide dinitrate (D), and satisfies the following weight ratios (1) through (3) of each of the components:     (1) A:B = 70:30 to 10:90, (2) the weight ratio of the component C based on the adhesive composition is 10 to 40% by weight, and (3) the weight ratio of the component D based on the adhesive composition is 20 to 35% by weight.   Provided is a patch excellent in percutaneous absorption, handleability, resistance to skin irritation, sustained release, adhesivity, etc. <IMAGE>
Patent NZ-333802-A (NZ)
Title: Antitumor antisense sequences directed against R1 and R2 components of ribonucleotide reductase
Inventor: WRIGHT JIM A
IPC: A61P35/00
Filed: 1997-08-01
Abstract: An antisense oligonucleotide comprising at least seven to about thirty-five nucleotides and a sequence complimentary to a sequence of a mammalian ribonucleotide reductase gene, or an analogue thereof.  The oligonucleotide is capable of inhibiting the proliferation of neoplastic cells.  Also disclosed is a method of evaluating a compound for its ability to regulate a Ras signalling pathway by assaying for an agonist or antagonist of the interaction of R2 and Raf-1 and/or Rac-1.  The method comprises providing a reaction mixture containing R2 and Raf-1 and/or Rac-1 under conditions which permit the interaction of R2 and Raf-1 and/or Rac-1, in the presence of a test compound; detecting the formation of complexes between R2 and Raf-1 and/or Rac-1 or activation of a Ras signalling pathway; and comparing to a control reaction in the absence of the test substance.  Lower levels of complexes or activation in the reaction mixture indicate that the test compound interferes with the interaction of R2 and Raf-1 and/or Rac-1, and higher levels indicate that the test compound enhances the interaction of R2 and Raf-1 and/or Rac-1.
Patent NZ-333866-A (NZ)
Title: Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents
Inventor: VENKATESHWARAN SRINIVASAN
IPC: A61L15/58
Filed: 1997-08-29
Abstract: A method of preparing a pressure sensitive adhesive matrix patch comprising the steps of: a) mixing an effective amount of a hydrophilic salt form of a drug like ketorolac tromethamine or diclofenac sodium with an aqueous dispersion of a hydrophobic pressure sensitive adhesive, wherein the aqueous dispersion comprises a water phase, b) film casting the mixture, evaporating the water phase to obtain a hydrophobic pressure sensitive film having the drug fully dissolved in it, c) laminating a release liner to the first surface of the matrix film and a drug impermeable backing layer to second surface. These patches are used for transdermal delivery of a pharmaceutical agent.
Patent NZ-334208-A (NZ)
Title: Prefabricated fireplace with ceramic fibre one piece fireplace box and decorative log set in box
Inventor: SHIMEK RONALD JOHN
IPC: F24C15/00
Filed: 1999-02-16
Abstract: Fireplace box 40 is formed in one piece from reinforced ceramic fibre.  Decorative log set 59 and decorative surround frame are provided for a prefabricated fireplace without the need for a separate housing.
Patent NZ-335993-A (NZ)
Title: Non-azeotropic refrigerant composition
Inventor: ROBERTS NEIL
IPC: C09K5/04
Filed: 1997-11-28
Abstract: Provided is a non-azeotropic refrigerant composition having a vapour pressure at -20oC of from 70 to 190kPa, at +20oC of from 510 to 630kPa and at +60oC of from 1620 to 1740 kPa, which composition comprises: 1 From 60 to 99% by weight of 1,1,2,2-tetrafluoroethane (R134), 1,1,1,2-tetrafluoroethane (R134a), difluromethoxytrifluoromethane (E125) or a mixture of two or more of these; 2 From 1 to 10% by weight of an unsubstituted hydrocarbon of the formula CnHm in which n is at least 4 and m is at least 2n-2; and 3 Up to 39% by weight of a vapour pressure depressant; and optionally 4 Up to 20% by weight of a flammability suppressant. Such a composition is reported to have substantially no ozone depletion potential and is sufficiently compatible with the conventional mineral oil lubricants to be used with them, and where in the operating performance is equal to or superior to conventional fluorocarbons.
Patent NZ-336525-A (NZ)
Title: Plastics bag, for packaging liquid, comprising a leaktight chamber and a pocket, adjacent the chamber, housing a pipe for withdrawing liquid from the chamber
Inventor: SAINT-SAUVEUR XAVIER DE
IPC: B65B3/02
Filed: 1997-12-19
Abstract: A bag 30 for packaging liquid formed by a plastic film, comprises a sealed chamber for liquid, a pocket 33 in which is located a conduit (straw 21) for withdrawing the liquid, and means 4 to give access to the inside of the pocket.  An opening is formed through part of the wall of pocket 33, adjacent the chamber, to allow the conduit to penetrate the chamber in a leaktight manner.  The opening is located at the end of a tubular element (seal 7a), of decreasing cross-section, at the point where the section is smallest.  The element is formed from a film of plastic forming one wall of the pocket adjacent to the chamber and is intended to accommodate the conduit and form a seal therearound.  The means for giving access to the inside of the pocket may comprise a tab 4a cut from one of the layers of film forming the chamber .
Patent NZ-336573-A (NZ)
Title: 4-Phenyl substituted phthalazin-1-one derivatives useful for treating airway disorders
Inventor: STERK GEERT JAN
IPC: C07D405/04
Filed: 1998-01-12
Abstract: The phthalazin-1-one derivatives or salts thereof have the formula I wherein: R1 is alkoxy which can be completely or predominantly substituted by fluorine; R2 is alkoxy, cycloalkoxy, cycloalkylmethoxy or alkoxy which is completely or predominantly substituted by fluorine; R3 and R4 are both hydrogen or together form an additional bond; R5 is R6, -CmH2m-R7, -CnH2n-C(O)R8, -CH(R9)2 or-CpH2p-Ar; R6 is hydrogen, alkyl, cycloalkyl, cycloalkylmethyl, alkenyl, alkynyl, phenylalkenyl, polycycloalkyl, naphthyl, pyridyl, pyrazinyl, pyridazinyl, pyrimidyl, quinazolinyl, quinoxalinyl, cinnolinyl, isoquinolyl, quinolyl, indanyl, benzoxazolyl, benzothiazolyl, oxazolyl, thiazolyl, N-methylpiperidyl, tetrahydropyranyl, tetrahydrothiapyranyl or an optionally substituted phenyl; R7 is hydroxyl, halogen, cyano, nitro, nitroxy, carboxyl, carboxyphenyloxy, phenoxy, alkoxy, cycloalkoxy, cycloalkylmethoxy, alkylcarbonyl, alkylcarbonyloxy, alkylcarbonylamino, alkoxycarbonyl, aminocarbonyl, mono- or dialkylaminocarbonyl, amino, mono- or dialkylamino, or an optionally substituted piperidyl, piperazinyl, pyrrolidinyl or morpholinyl; R8 is an optionally substituted phenyl, naphthyl, phenanthrenyl or anthracenyl; R9 is -CqH2q-phenyl; Ar is a naphthyl, pyridyl, pyrazinyl, pyridazinyl, pyrimidinyl, quinazolinyl, quinoxalinyl, cinnolinyl, isoquinolyl, quinolyl, benzimidazolyl, benzoxazolyl, benzothiazolyl, benzotriazolyl, N-benzosuccinimidyl, imidazolyl, pyrazolyl, oxazolyl, thiazolyl, furyl, thienyl, pyrrolyl, 2-alkyl-thiazol-4-yl or an optionally substituted phenyl; m is 1 to 8; n is 1 to 4; p is 1 to 6 and q is 0 to 2. A pharmaceutical composition thereof is useful for treating an airway disorder.
Patent NZ-503251-A (NZ)
Title: Reinforcement assembly for supporting structures comprising CFK panel and anchor
Inventor: SCHWEGLER GREGOR
IPC: E04G23/02
Filed: 1998-08-18
Abstract: A carbon fibre reinforcing assembly for supporting elements (1), such as concrete beams for bridges. The carbon fibre reinforcing assembly comprises a carbon fibre panel (2) and at least one anchor (3). The panel (2) is joined to the anchor (3) by adhesively fixing the split ends of the panel (2') into the receiving grooves (9) of the anchor.  The carbon fibre reinforcing assembly is adhesively fixed (5) to the supporting element (1) and pretensioned with tension rod (8).
Patent NZ-503537-A (NZ)
Title: Clostridium toxin, and method for preparing immunogenic compositions
Inventor: GIBERT MARYSE
IPC: C12N15/31
Filed: 1998-09-17
Abstract: An isolated nucleic acid comprises the sequence shown in SEQ ID NO: 2 and has transcriptional promoter activity. The nucleic acid can comprise the promoter of the beta 2 toxin of Clostridium perfringens. An immunogenic composition comprising the toxoid of a recombinant beta 2 toxin is described. Also described are vectors that comprise the nucleic acid sequence, cells transfected with the vector and processes for producing the immunogenic compositions.
Patent NZ-506035-A (NZ)
Title: Cheese block forming tower with controller controlling severing of the cheese block in response to curd to cheese conversion pressing time and controlling supply of curd to the tower
Inventor: MISSON GREGORY CHARLES
IPC: A01J25/11
Filed: 1999-12-02
Abstract: A number of cheese block forming towers are fed curds from a central vat. Curd accumulates in each tower and its weight causes whey to be expressed. Individual blocks are severed from the bottoms of the columns of curd by guillotine blades. A controller monitors both the output of each severing device (rate of discharge of blocks and their weight) and the rate of use of curd in each tower. The latter is determined by the same time that the level of curd takes to drop from sensor to sensor. These factors may then be used to adjust the output of severing devices or the charge rate of curd to balance the outputs of the multiple tower
Patent NZ-514832-A (NZ)
Title: Deformable building sheet batten
Inventor: EATON PETER FRANCIS
IPC: E04B9/22
Filed: 2000-04-14
Abstract: A batten (100) for mounting cladding sheets (300) to a wall or frame (50) includes an elongate channel member having a pair of side walls that are spaced apart (120, 140).  The side walls are joined by an intermediate web (110), and a corresponding pair of mounting flanges (125, 145) spaced outwardly from the web (110) and extending laterally from the side walls (120, 140).  The web (110) is constructed for connection to the wall or frame, whereas, the mounting flanges (125, 145) are constructed for connection to the cladding sheets. The overall design of the batten (100) results in preferential deformation of the cladding batten when stress is applied to the cladding sheets (300).
Patent NZ-515517-A (NZ)
Title: A water powered engine with water superheated by electric element at moment of demand, and zero water consumption
Inventor: WHITE WILLIAM LLEWIS
IPC: F01B17/04
Filed: 2001-11-15
Abstract: Disclosed is an internal expansion engine fuelled solely by superheated water which is provided at the moment of demand by an expansion chamber mounted electric heating element. The water is stated to create power via thermal expansion in the engine and the superheated water after use is condensed and recirculated in a closed circuit to arrive at zero consumption of water.
Patent NZ-524573-A (NZ)
Title: New oxabispidine compound useful in the treatment of cardiac arrhythmias
Inventor: BJORSNE MAGNUS
IPC: A61P9/06
Filed: 2001-10-01
Abstract: 4-({3-[7-(3,3-dimethyl-2-oxobutyl)-9-oxa-3,7-diazabicyclo[3.3.1]-non-3-yl]propyl}amino)benzonitrile, benzenesulfonic acid salt, optionally in the form of a monohydrate, useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
Patent NZ-524800-A (NZ)
Title: Gate valve with delayed retraction of counter plate
Inventor: YOUNG STEVEN P
IPC: F16K51/02
Filed: 2002-07-19
Abstract: A valve, such as a gate valve (10), includes a housing (12) having a fluid conduit (14) and defining a valve seat (16) and a support surface (18), a seal plate (20), a counter plate (22), an actuator (34) for moving the seal plate and the counter plate between an open position and a closed position, and a coupling mechanism (50) operatively coupled between the seal plate, the counter plate and the actuator. The seal plate is in sealed engagement with the valve seat, and the counter plate is in engagement with the support surface in the closed position. The coupling mechanism retracts the counter plate from the support surface subsequent to retraction of the seal plate from the valve seat as the valve is opened.
Patent NZ-526028-A (NZ)
Title: Backlighting system for display screen utilised to control the distribution of power to at least one light source
Inventor: PEASE RICHARD WILLIAM
IPC: H05B41/392
Filed: 2003-05-21
Abstract: A power distribution system for at least one light source 5 within a display apparatus is disclosed. Distribution of power is controlled by detecting the electrical power consumed by the light source, determining whether the consumption is within predetermined limits, and regulating the power supplied to the light source to maintain or return the power consumption within the limits. The invention has particular application to controlling power supplied to backlighting in a multi-layer LCD display.
Patent NZ-529711-A (NZ)
Title: Support for information display unit with at least one display surface
Inventor: L HOTEL FRANCOIS
IPC: A47F5/11
Filed: 2002-05-03
Abstract: The support comprises at least one sheet of a substantially rigid and foldable material having the presentation face (11), stressing means (10, 20, 21) for bending the presentation face (11) of the sheet and means (9, 19, 5) for keeping the presentation face (11) of the sheet in the bent state, which holding means oppose the stressing means (10). The holding means opposing the stressing means (10) for keeping the presentation face (11) of the sheet bent are designed so that their action is exerted at discreet points distributed along the presentation face (11) of the sheet by a plurality of strips (9).
Patent NZ-530597-A (NZ)
Title: Anastomotic device
Inventor: PARK ADRIAN EDWARD
IPC: A61B17/32
Filed: 2002-06-20
Abstract: The present invention is directed to gastrointestinal or enteric (including biliary) anastomosis and the like. The anastomotic device of the invention is a three dimensional woven tube of wire preferably formed from a thermal, smart memory metal. The outer loops or ends of the tube fold or loop back on deployment in a manner which holds the luminal interface of the anastomotic site into apposition at the deployment site. The women tube is deployed using a canula with a retractable outer sleeve.
Patent NZ-533367-A (NZ)
Title: A device for lifting a wearer
Inventor: MANU DEACON TEHANAKORE
IPC: A61F13/06
Filed: 2004-06-08
Abstract: A device for lifting a wearer, the device comprising a sleeve of flexible material adapted to receive and be fastened to a wearer's limb, the sleeve having a pocket which may be filled with material to provide a projecting grip by which the sleeve may be grasped for lifting the wearer.
Patent NZ-535932-A (NZ)
Title: A safety actuation device for a dish-washing machine
Inventor: PARDINI GIANLUCA
IPC: A47L15/42
Filed: 2004-10-14
Abstract: Disclosed is a safety actuation device (4) for a dish-washing machine (1), comprised of a fixing element (15) designed to be fixed to a supporting structure (2) of the dishùwashing machine (1), an electric motor (9), a pin (14) designed to rotate in a circular way, and a transmission assembly (11) for transmitting motion from the motor (9) to the pin (14). The device is comprised of a bar element (17), which has a fixed first end portion (l7a) and a free second end portion (17b) and is designed to move fixedly with the electric motor (9) , and a switch (19), which can be actuated by the bar element (17) and is designed to interrupt electrical supply to the electric motor(9).
Patent NZ-538588-A (NZ)
Title: Drive mechanism for switching installation and method for operating it
Inventor: NITERT GERHARDUS LEONARDUS
IPC: H01H31/00
Filed: 2003-08-15
Abstract: A mechanism for moving a plurality of disconnectors (73) from a position where electrical connections are formed between the respective poles of corresponding switching elements (35) and a rail contact, into a position where the electrical connections are broken is disclosed. The mechanism has a drive shaft (77) attached to a radially projecting strip (78), to which a toggle strip (80) is rotatably secured and able to move in a plane perpendicular to the drive shaft. The other end of the toggle strip is rotatably connected to a disconnector bar (82) which can move in a linear direction and is connected via drive rods (76) to the disconnectors.
Patent NZ-540011-A (NZ)
Title: Energy efficient window
Inventor: WINFIELD ALAN H
Filed: 2002-11-13
Abstract: An energy insulating window includes a pair of outer glass panes (10, 12) held apart by a spacing member (16) and surrounded by a frame. One frame member (26) serves as a desiccant concealing member which holds a removable desiccant cartridge (44) containing desiccant (40). The desiccant cartridge connects to a conduit system (42) providing gas communication to the air space between the glass panes (10, 12).