Patent CA-3086767-A1 (CA)
Title: Oral liquid pharmaceutical compositions of aminosalicylates
Inventor: LIANG ALFRED CHI-YEH
IPC: A61K9/50
Filed: 2019-01-02
Abstract: CA 03086767 2020-06-23 (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 1 11111 1111111 11 111111 111 11111 11111111 1 1 111 1111 1111 111 11111 1111 111 11111111111 111 1111 Organization International Bureau (10) International Publication Number (43) International Publication Date WO 2019/136053 Al 11 July 2019 (11.07.2019) WIPO I PCT (51) International Patent Classification: A 61K 9/00 (2006.01) A61K 9/16 (2006.01) Declarations under Rule 4.17: A61K 9/10 (2006.01) A61K 9/50 (2006.01) ¨ as to applicant's entitlement to apply for and be granted a patent (Rule 4.17(ii)) (21) International Application Number: ¨ as to the applicant's entitlement to claim the priority of the PCT/US2019/012032 earlier application (Rule 4.17(iii)) (22) International Filing Date: Published: 02 January 2019 (02.01.2019) ¨ with international search report (Art. 21(3)) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/613,198 03 January 2018 (03.01.2018) US (71) Applicant: FERRING B.V. [NL/NL]; Polaris Avenue 144, 2132 JX Hoofddorp (NL). (72) Inventors; and (71) Applicants (for US only): LIANG, Alfred Chi-Yeh [US/US]; c/o ',ERRING B.V., Polaris Avenue 144, 2132 JX Hoofddorp (NL). EHRNSPERGER, Eric [11S/11S]; c/o ',ERRING B.V., Polaris Avenue 144, 2132 JX Hoofddorp (NL). SHEN, Xiaohong [US/US]; c/o FERRING B.V., Po-laris Avenue 144, 2132 JX Hoofddorp (NL). = (74) Agent: BRINCKERHOFF, Courtenay et al.; FOLEY & LARDNER LLP, 3000 K Street NW, Suite 600, Washing-ton, District of Columbia 20007-5109 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). re) re) (54) Title: ORAL LIQUID PHARMACEUTICAL COMPOSITIONS OF AMINOSALICYLATES (57) Abstract: Described herein are oral liquid pharmaceutical compositions for the oral administration of an aminosalicylate, as well as methods of making such oral liquid pharmaceutical compositions, and therapeutic methods for using them. The oral liquid phar-maceutical compositions comprise extended-release microparticles formulated with an aminosalicylate, wherein the extended-release microparticles are provided with an outer delayed release coating.