baber/WOPTO huggingface dataset:
Patent JP-4180826-B2 (JP)
IPC: C07K14/18
Filed: 2001-03-15
Granted: 2008-11-12
Abstract: The present invention relates to the IL-12p40 subunit mutant gene which can produce IL-12 (interleukin 12) of human and mouse origin with high activity, the expression vector including above mutant gene and the use of them to DNA vaccine adjuvant. Particularly, it relates to IL-12p40 mutant gene which inhibits the secretion of IL-12p40 but normally secretes active IL- 12p70 by making mutation at Asn-222 (human) or Asn- 220 (mouse) amino acid of IL-12p40, which acts as a competitive inhibitor of active form of IL-12, IL-12p70. Therefore, the IL-12p40 mutant gene of the present invention can be useful for DNA vaccination and gene therapy against various diseases, for example, AIDS, hepatitis C or hepatitis B, cancer, influenza, tuberculosis and malaria, which essentially require cellular immune responses for their therapy.
Patent JP-4927286-B2 (JP)
IPC: C12N1/21
Filed: 2001-03-12
Granted: 2012-05-09
Abstract: The present invention relates to novel subtilases having an improved wash performance on egg stains. The present invention also relates to isolated nucleic acid sequences encoding the subtilases, nucleic acid constructs, recombinant expression vectors, host cells comprising the nucleic acid construct, and methods for producing and using the subtilases of the invention. Further, the present invention relates to cleaning and detergent compositions comprising the subtilase enzymes of the invention as well as to use of such enzymes in detergent compositions and for removal of egg stains.
Patent JP-4753521-B2 (JP)
IPC: H04Q9/00
Filed: 2001-04-17
Granted: 2011-08-24
Abstract: The invention concerns a method and a device for monitoring enablement of an electrical apparatus connected to a power grid. The method consists in: transmitting (A) from a specialised transmitter (ES) to the electrical apparatus (EA) a coded information message comprising an enablement information, in accordance with an enablement control code; and in receiving (B) by means of a receiver (R) equipping the electrical apparatus (EA) said information message. The latter is decoded (C) in accordance with specific enablement data integrated in the receiver (R) to generate decoded enablement data. The enablement of the electrical apparatus (EA) is granted (D, E) if the decoded data are in conformity with the integrated specific enablement data and enablement is refused (D, F) otherwise. The invention is useful for protecting electrical appliances against theft, for managing service delivery on a distant site, monitoring contractual terms.
Patent JP-3853279-B2 (JP)
IPC: H01S5/0232
Filed: 2002-10-10
Granted: 2006-12-06
Abstract: A semiconductor laser device that is suitable for mass production, that permits an improved wire layout, and that permits miniaturization includes leads disposed through each of two side faces of an insulating frame member so as to run from outside to inside the insulating frame member, an LD and a light-receiving element mounted inside the insulating frame member, and wires laid inside the insulating frame member so as to connect the leads to the electrodes of the LD and the light-receiving element. Inside the insulating frame member, the tip of one lead is extended farther inward than the edge of an element mount portion that faces the tip of another lead that is disposed through the same side face of the insulating frame member.
Patent JP-4885408-B2 (JP)
IPC: A61K9/48
Filed: 2001-07-17
Granted: 2012-02-29
Abstract: The present invention provides a biodegradable article formed from enzyme-synthesized amylose using phosphorylase, wherein the enzyme-synthesized amylose is composed of glucose monomers exclusively bonded by  alpha -1,4-glucosidic likage and has a weight average molecular weight of not less than 100 kDa, preferable not less than 600 kDa. The enzyme-synthesized amylose employed in the present invention has a molecular weight distribution (Mw/Mn) of not more than 1.25 and can be chemically modified if desired. The biodegradable article of the present invention can be produced by (a) the enzyme-synthesized amylose and/or its modified one, or a combination of the amylose (a) and another polymer material (b).
Patent JP-4227407-B2 (JP)
IPC: A61K38/08
Filed: 2001-10-18
Granted: 2009-02-18
Abstract: The invention relates to a vaccine which comprises at least one antigen and a peptide comprising a sequence R1—XZXZNXZX—R2, whereby N is a whole number between 3 and 7, preferably 5, X is a positively charged natural and/or non-natural amino acid residue, Z is an amino acid residue selected from the group consisting of L, V, I, F and/or W, and R1 and R2 are selected independently one from the other from the group consisting of —H, —NH2, —COCH3, —COH, a peptide with up to 20 amino acid residues or a peptide reactive group or a peptide linker with or without a peptide; X—R2 may also be an amide, ester or thioester of the C-terminal amino acid residue, as well as the use of said peptide for enhancing a patient's adaptive immune response to an antigen.
Patent JP-4890733-B2 (JP)
IPC: A61K38/00
Filed: 2001-11-16
Granted: 2012-03-07
Abstract: The invention relates to pharmaceutical compositions of an approx 60kDa polypeptide (or its encoding nucleic acid molecules) or functionally equivalent molecules or fragments thereof from  Mycobacterium tuberculosis  or related prokaryotes in the treatment of non-cancerous pathological conditions such as autoimmune and allergic disorders.
Patent JP-4594585-B2 (JP)
IPC: H04M1/72415
Filed: 2001-11-14
Granted: 2010-12-08
Abstract: The location of unmodified wireless assets in a wireless communication network may be identified using time differences of arrivals of a communication sequence at different network receivers. Time-stamping devices may include correlator circuits in parallel with signal decoders to time-stamp communication sequences. Cellular wireless networks may be frequency-multiplexed to increase spatial time-stamping density. Tags may be attached to passive assets to provide location identification information to network devices. Locations of assets broadcasting standard 802.11 radio frequency structures may be identified. Noise inherent in correlating a communication sequence may be reduced by using a selected correlation function.
Patent JP-4054372-B2 (JP)
IPC: B21D53/04
Filed: 2001-12-07
Granted: 2008-02-27
Abstract: Fabrication of a one side flat aluminum integrated circuit panel consists of preparing the surface of two aluminum alloy sheets, depositing on one of the sheets an anti-weld ink in reserved zones corresponding to the circuit design, roll-bonding the sheets and expanding the channels corresponding to the non-welded zones with a pressurized fluid. One of the sheets is made of series 1000 alloy and the other is made of an alloy of iron and manganese in which Fe+Mn is greater than 0.8 wt %, preferably greater than 1% or even 1.5%.  An Independent claim is also included for the continuous fabrication of integrated circuit panels formed from at least three metal strips.
Patent JP-4284495-B2 (JP)
IPC: B29C33/76
Filed: 2002-02-05
Granted: 2009-06-24
Abstract: Process and apparatus (10) for forming plastics by heating an open mold (12) and contacting the open mold (12) with plastic particulate material (16) held within a container (14) to form a melted skin on the mold (12), and resulting articles made therefro. The mold (12) is provided with a carrier (18), which may include heating and cooling lines for achieving a desired mold temperature. Single skin molded articles may be multi-layered with or without paint on the surface. Multiple skin moled articles may include sandwiched layers of plastic filler or expandable foam filled centers, with or without various inserts or reinforcements.
Patent JP-4164023-B2 (JP)
IPC: H04B1/04
Filed: 2002-04-10
Granted: 2008-10-08
Abstract: A method for digital transmission using an AM transmitter includes operating an output stage of the AM transmitter in a linear mode and correcting the supply voltage of the output stage in the linear mode as a function of an instantaneous drive so as to improve efficiency. The correcting is performed by operating the modulator of the AM transmitter as a switched-mode power supply unit so as to deliver a corrected supply voltage to the output stage, and scanning an envelope of a complex modulated data signal so as to control the correcting. A time constant during the scanning of the envelope enables immediate following of a rise in the envelope. The complex modulated data signal is delayed after the scanning so as to perform the correcting during the delay and prevent an overdriving of the output stage.
Patent JP-4215636-B2 (JP)
IPC: C12M1/00
Filed: 2002-07-05
Granted: 2009-01-28
Abstract: The invention relates to a biochip comprising a substrate presenting a reflecting main surface and wherein the main surface presents localized sites that are made sensitive to fluorescence detection by a transparent layer having optical thickness (2k+1)λ/4 where k is a positive or zero integer and where λ designates a wavelength lying between a wavelength λ0 at which fluorescence is excited and a wavelength λ1 at which fluorescence is emitted. The biochip can be manufactured by depositing a transparent layer of thickness mλ′/2 on a substrate and by making studs or wells of thickness (2k+1)λ/4 in said layer to form said sensitive sites.
Patent JP-4177256-B2 (JP)
IPC: C08J3/075
Filed: 2002-10-01
Granted: 2008-11-05
Abstract: This invention relates to a method for purifying and drying a polymer hydrogel. This invention is based in part upon the discovery that rapid drying of polymer hydrogels can eliminate the problem of unacceptable levels of soluble oligomers caused by prolonged thermal treatment. Rapid drying techniques allow drying hydrogels containing more water than was previously considered possible without a loss in product quality. Furthermore, it was discovered that slurries comprising polymer hydrogels and large quantities of water can be spray dried and that spray drying can be conducted with only minimal oligomer formation.
Patent JP-4223401-B2 (JP)
IPC: G01N27/64
Filed: 2002-09-25
Granted: 2009-02-12
Abstract: An array of probes is provided wherein the probes are maintained in place in bores extending through a housing by a friction force applied to the probes. The friction force can be overcome by another force applied to the probes, thereby allowing the probes to move to a new position within the bore. In one embodiment, the probes contain an internal conduit through which liquid samples are introduced into the probes. Thereafter, the probes are moved to contact a substrate surface to move the probes to a new position, the configuration of which replicates the substrate surface configuration. The housing is then raised a predetermined distance to allow sample to be accurately deposited on the substrate surface from a desired height above the substrate surface. The probes are then returned to their original position.
Patent JP-4440643-B2 (JP)
IPC: C21D11/00
Filed: 2002-11-21
Granted: 2010-03-24
Abstract: A method and device for controlled straightening and cooling of a wide metal strip, especially a steel strip or sheet metal, running out of a hot rolled strip rolling mill, using pinching rollers arranged in the moving direction of the strip behind vertical double rollers, said pinching rollers producing a tensile stress acting in a longitudinal direction. According to the invention, the range of use of conventional sheet metal cooling systems can be extended to obtain a more even surface of said steel strip with an increased cooling effect. This is achieved by displacing the metal strip or sheet metal between a pre-straightening machine and splash cooling facility in defined conditions of tensile stress by adjusting the tensile stress and by cooling said strip or sheet metal inside said splash cooling facility between successive pairs of pinching rollers and by additionally controlling the tensile stress.
Patent JP-4248406-B2 (JP)
IPC: H04M11/00
Filed: 2003-02-11
Granted: 2009-04-02
Abstract: A communications switch comprising a plurality of numerically identified input traffic ports, a plurality of numerically identified output traffic ports, at least one significant label extractor and at least one numerical processor, the communications switch being arranged whereby each message entering the communication switch by a numerically identified input traffic port contains a header, which header contains a label stack, which label stack includes at least one valid label, of which one valid label is a significant label. The numerical value of the significant label contained within the header of a particular message which entered the communications switch via a particular numerically identified input traffic port is extracted by the at least one significant label extractor and is supplied to one of the at least one numerical processors. The numerical processor uses the significant label of the particular message and the numerical value of the particular numerically identified input traffic port to form a numerical result which directly equates to the number of the numerically identified output traffic port by which the particular message leaves the communications switch and wherein the numerical result is equal to the modulo addition of the numerical value of the significant label and the numerical value of the particular numerically identified input traffic port.
Patent JP-4615864-B2 (JP)
IPC: A61P19/08
Filed: 2003-02-20
Granted: 2011-01-19
Abstract: Compounds formula (IA) or (IB), wherein W represents HO(C═O)—, HONH(C═O)— or H(C═O)N(OH)—; X represents —O— or —S—; and R1, R2, and R3 are as defined in the description and claims, are inhibitors of matrix metal oproteinases, in particular MMP9 and/or MMP12.
Patent JP-4458854-B2 (JP)
IPC: F16K47/08
Filed: 2003-03-19
Granted: 2010-04-28
Abstract: A noise reduction device for use in a fluid flow system comprises a central section and an outer annular section. The outer annular section is designed to reduce the velocity of an annular fluid flow relative to a central core fluid flow. The central section of the device has a plurality of apertures, while the annular section has upstream apertures communicating with a pressure reduction chamber and downstream apertures. The upstream apertures of the annular section are smaller than, and off set from, the downstream apertures of an annular section to increase the pressure reduction and further reduce the velocity of the fluid flow in an annular section. A method is also described for reducing noise transmissions from a piping system wherein the fluid flow through the piping system is separated into an annular fluid flow and a core fluid flow, and the velocity of the annular fluid flow is reduced relative to the core fluid flow.
Patent JP-4574251-B2 (JP)
IPC: H01L21/52
Filed: 2004-07-07
Granted: 2010-11-04
Abstract: Extremely thin chips laminated to a non-ultraviolet ray curing type adhesive tape are peeled from the tape without giving rise to cracks and chippings. In a center portion of a suction block used for peeling off a chip laminated to a dicing tape, three blocks which push the dicing tape upwardly are incorporated. With respect to these blocks, inside the first block having a largest diameter, there is a second block having a diameter smaller than the diameter of the first block. Further, inside the second block, there is a third block having the smallest diameter. To peel off a chip by pushing a back surface of the dicing tape with the blocks, first of all, the three blocks are simultaneously pushed upwardly by a certain amount and, thereafter, the intermediate block and the inner block are further pushed upward, and, finally, the inner block is further pushed upward.
Patent JP-4845367-B2 (JP)
IPC: G03G15/20
Filed: 2004-10-22
Granted: 2011-12-28
Abstract: A fixing apparatus of an image forming apparatus with high productivity for heavy paper is provided that prevents an abnormal temperature rise of a heated material after a continuous printing operation of heavy paper ends. If the value of a temperature sensor that is provided in a non-passing region of the heated material is equal to or greater than a predetermined value at the end of the continuous printing, the cooling device of a pressure member is operated before the apparatus is put into a standby state, so that the heating member is rotated while the pressure member presses the heating member.
Patent JP-4329678-B2 (JP)
IPC: H01L23/50
Filed: 2004-11-11
Granted: 2009-09-09
Abstract: <P>PROBLEM TO BE SOLVED: To suppress the peeling of the inside of a mold resin while suppressing the occurrence of a resin flash on the external connection surface of a lead, in a semiconductor device in which a semiconductor element is mounted on the element mounting part of a lead frame through a die-mount material and which is sealed up with a mold resin so that the external connection surface of the lead of a lead frame is exposed.  <P>SOLUTION: A semiconductor device 100 comprises a lead frame 10 composed of an element mounting part 11 and a lead 12, a semiconductor element 30 which is mounted on the upper surface of the element mounting part 11 through a die mount material 20 of resin electrically connected to the lead 12, and a mold resin 50 which seals them so that the external connection surface 12a of the lead 12 is exposed. A roughening process for improving adhesion to resin is applied to a part positioned inside the mold resin 50 among the surface of the lead frame 10 while no roughening process is applied to the external connection surface 12a of the lead 12.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-4434942-B2 (JP)
IPC: A01M1/20
Filed: 2002-05-06
Granted: 2010-03-17
Abstract: The device forms a single unit that includes the means by which the evaporation of active substances is achieved, as well the means that allow automatically lighting a small lamp or LED that emits a small light illuminating the container (5) of the active substance to be evaporated, allowing to see the content in the dark and, in addition, constituting a light in the dark for the area surrounding the device, with the particularity that the volume of this device does not increase with respect to the devices meant to individually evaporate active substances and emit a light. The design of the device includes a general casing (1) comprising a pinholder body (3) for a plug (7) and the container (5) itself for the active substance, in such a way that the body (3) incorporates a sensor (13) that emits a signal for the automatic activation of the lamp or illumination LED when the light intensity is below a pre-established threshold. <IMAGE>
Patent JP-4449745-B2 (JP)
IPC: B24B37/00
Filed: 2003-04-28
Granted: 2010-04-14
Abstract: A polishing slurry comprising an oxidant, a metal oxide dissolver, a metal inhibitor and water and having a pH from 2 to 5, wherein: 
the metal inhibitor contains one or more types selected from the group (C-group) consisting of aromatic compounds having a triazole skeleton and one or more types selected from the group (D-group) consisting of aliphatic compounds having a triazole skeleton, compounds having a pyrimidine skeleton, compounds having an imidazole skeleton, compounds having a guanidine skeleton, compounds having a thiazole skeleton and compounds having a pyrazole skeleton.
Patent JP-4499563-B2 (JP)
IPC: C01B33/18
Filed: 2003-07-01
Granted: 2010-07-07
Abstract: Modified silica fillers are prepared by contacting silica with blends or mixtures containing diorganodihalosilanes and monoorganotrihalosilanes in weight ratios of 1:0.1 to 1:2, respectively. While dialkyldichlorosilanes and monoalkyltrichlorosilane such as dimethyldichlorosilane and methyltrichlorosilane, respectively, are most preferred, the blends or mixtures may also comprise compositions containing n-propyltrichlorosilane, phenyltrichlorosilane, cyanopropyltrichlorosilane, and mercaptopropyltriethoxysilane.
Patent JP-4975964-B2 (JP)
IPC: A61K9/127
Filed: 2003-06-26
Granted: 2012-07-11
Abstract: A method for producing a cationic liposomal preparation comprising a lipophilic active compound with physical and chemical stability during manufacturing, storing and reconstituting, and further a cationic liposomal preparation obtainable by this method as well as specific cationic liposomal preparations as well as pharmaceutical compositions are disclosed.
Patent JP-4194564-B2 (JP)
IPC: F02M61/10
Filed: 2005-01-11
Granted: 2008-12-10
Abstract: An injection nozzle for an internal combustion engine has valve means (22, 80) moveable within a bore (24) of a nozzle body (26), the valve means (22, 80) having a first seat (36, 82) and a second seat (40, 102), both being engageable with a seating surface (28), which has a seat cone angle (θS), to control fuel delivery through a nozzle outlet (30). The first seat (36, 82) controls delivery of fuel from a first supply chamber (38) to a delivery chamber (34) and the second seat (40, 102) controls delivery of fuel from a second supply chamber (42) to the delivery chamber (34), the second supply chamber (42) being in communication with the first supply chamber (38) by way of a flow path (46, 54; 92, 94) defined within the valve member (22, 80). By virtue of the provision of the first and second valve seats (36, 82; 40, 102), the flow path (54, 46; 92, 94) and the delivery chamber (34), the injection nozzle exhibits improved fuel delivery characteristics. <IMAGE>
Patent JP-4632353-B2 (JP)
IPC: H01M2/30
Filed: 2005-03-08
Granted: 2011-02-16
Abstract: <P>PROBLEM TO BE SOLVED: To provide the connection structure of a storage element capable of surely conducting positioning in assembly, increasing the fastening torque of a metallic bar, and increasing radiation, and to provide a storage element module equipped with the connection structure.  <P>SOLUTION: The connection structure of the storage element conductively connecting a plurality of storage elements 1 with the metallic bar 3 and fixed to a circuit board 3 is equipped with a support 10 having an element side screwing part screwed to a terminal 1a of the storage element 1 and a board side screwing part formed coaxially with the element side screwing part and screwing with a screwing member on the circuit board side, the metallic bar 2 is interposed between the support 10 and the terminal 1a, the element side screwing part is screwed with the terminal 1a, the circuit board 3 is interposed between the support 10 and the screwing member, and the board side screwing part is screwed with the screwing member 22.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-4645281-B2 (JP)
IPC: H04L69/40
Filed: 2005-04-19
Granted: 2011-03-09
Abstract: An information processing apparatus for performing communication with another information processing apparatus via a network includes an instruction section instructing a transmission of a first packet in order to obtain a response from the other information processing apparatus; a first generation section generating a first time stamp containing a time when the first packet generated on the basis of instructions by the instruction section is sent out to the network; a second generation section generating a second time stamp containing a time when a second packet that is transmitted as a response for the first packet from the other information processing apparatus is obtained from the network; and a computation section computing a round trip delay between the information processing apparatus and the other information-processing apparatus on the basis of the first and second generated time stamps.
Patent JP-4807964-B2 (JP)
IPC: B26F3/12
Filed: 2005-05-06
Granted: 2011-11-02
Abstract: The device comprises a wire bow (2) joined with its lower ends to two vertically positioned conductive elements (4) each secured inside the ceramic housing (1) with two nuts (8a, 8b) attached to its lower ends. The housing (1) is provided with circular openings (13) at both sides in order to be joined with a short bar to the loom or larger industrial weaving or knitting machine. The bar is fixed with a clamping element (16) locked with a screw (21).