baber/WOPTO huggingface dataset:
Patent NZ-617507-A (NZ)
Title: Halogen-alkyl-1,3 oxazines as bace1 and/or bace2 inhibitors
Inventor: WOLTERING THOMAS
IPC: C07D413/12
Filed: 2012-06-04
Abstract: The present disclosure provides compounds of formula (I) having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present disclosure are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer’s disease and type 2 diabetes. Examples of compounds of formula (I) are: (S)-N-(3-(2-amino-4-(difluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl)-4-fluorophenyl)-5-cyanopicolinamide and (S)-N-(3-(2-amino-5,5-difluoro-4-(fluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl)-4-fluorophenyl)-5-cyanopicolinamide.
Patent NZ-618111-A (NZ)
Title: Freeze-dried aripiprazole formulation
Inventor: HIRAOKA SHOGO
IPC: A61K9/19
Filed: 2012-06-07
Abstract: Disclosed are spray freeze-dried aripiprazole powder formulations that exhibit improved dispersibility in a homogenous suspension when reconstituted with water. The freeze-dried aripiprazole formulations are obtained by a process comprising the steps of spray-freezing an aripiprazole suspension containing (I) aripiprazole, (II) a vehicle for the aripiprazole, and (III) water for injection, and drying the formulation.
Patent NZ-629177-A (NZ)
Title: Processing biomass
Inventor: MEDOFF MARSHALL
IPC: A23K10/32
Filed: 2007-10-26
Abstract: Disclosed is a method comprising: burning a lignin-containing residue to generate energy, wherein the lignin-containing residue is a post-distillate solid produced by: irradiating a lignocellulosic material, saccharifying the lignocellulosic material utilizing an enzyme, fermenting the saccharified material utilizing an organism to produce a fermentation product, and distilling the fermentation product from the lignin-containing residues, wherein irradiating comprises treating with electron beam radiation.
Patent NZ-703647-A (NZ)
Title: Notum protein modulators and methods of use
Inventor: STULL ROBERT A
IPC: C07K16/40
Filed: 2011-08-26
Abstract: Disclosed is an isolated anti-Notum antibody with the CDRs of the antibodies designated SC2.D2.2, SC2.A109, SC2.D23, SC2A101 or SC2.D57 as defined herein.
Patent NZ-706745-A (NZ)
Title: Methods of treatment of pancreatic cancer
Inventor: DESAI NEIL P
IPC: A61P35/00
Filed: 2011-05-20
Abstract: Disclosed is a method of treating pancreatic cancer in an individual in need thereof comprising administering to the individual an effective amount of a composition comprising nanoparticles comprising a taxane and an albumin, wherein the individual has progressed on a gemcitabine-based therapy. The pancreatic cancer is recurrent, resistant or refractory pancreatic cancer. The treatment can occur after at least 6 months after prior therapy, such as gemcitabine-based therapy. The therapy can be a mono-therapy or a combination therapy with another chemotherapeutic agent such as vandetanib.
Patent NZ-714501-A (NZ)
Title: Credential management system
Inventor: NEAFSEY JEFFREY S
IPC: H04L9/00
Filed: 2013-02-13
Abstract: Disclosed is an apparatus, for receiving a credential request from a customer computer to assign a virtual credential to a mobile device and transmitting the virtual credential to the mobile device wherein the credentials are of at least two different types. The apparatus includes one or more servers in communication with a plurality of customer computers. The one or more servers are configured with non-transitory computer executable instructions to manage credentials of a plurality of different formats and for at least two different regions, to allocate portions of the credentials to customers, to receive credential requests from the customer computers to assign virtual credentials from the portion of allocated credentials to end-users, to generate virtual credentials in response to the credential requests, and to deliver the virtual credentials to mobile devices. The one or more servers are configured with non-transitory computer executable instructions to encrypt the virtual credentials, to encapsulate the encrypted credentials in packages, and to deliver the virtual credentials to the mobile devices by transmitting the packages to the mobile devices. Each virtual credential is of a particular format and encoded for a particular region for each end-user and their respective mobile device. The plurality of different formats include prox, MIFARE classic, MIFARE DESFire EV1, optical, bar code, and QR code, wherein at least one of the formats includes either MIFARE classic or MIFARE DESFire EV1.
Patent NZ-719185-A (NZ)
Title: Crystalline forms of therapeutic compounds and uses thereof
Inventor: ENLOW ELIZABETH
IPC: C07D491/107
Filed: 2014-10-31
Abstract: Described herein is certain crystalline forms of 7-(3-(4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxyquinazolin-7-yloxy)propyl)-2-oxa-7-azaspiro[3.5]nonane, as well as pharmaceutical compositions employing the crystalline forms. Also provided are particles (e.g., nanoparticles) comprising such crystalline forms or pharmaceutical compositions. In certain examples, the particles are mucus penetrating particles (MPPs). The present invention further relates to methods of treating or preventing diseases using crystalline forms or pharmaceutical compositions.
Patent NZ-719754-A (NZ)
Title: Synergistic pesticidal compositions and related methods
Inventor: GOMEZ LUIS E
IPC: A01N43/56
Filed: 2014-10-17
Abstract: A pesticidal composition comprises a synergistically effective amount of a pyrethroid-based or pyrethrin-based sodium channel modulator compound and a pesticide selected from N (3 chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl)-N-ethyl-3-((3,3,3-trifluoropropyl)thio)propanamide (I), N (3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl)-N-ethyl-3-((3,3,3-trifluoropropyl) sulfinyl) propanamide (II), or any agriculturally acceptable salt thereof. A method of controlling pests comprises applying the pesticidal composition near a population of pests. A method of protecting a plant from infestation and attack by insects comprises contacting the plant with the synergistic pesticidal composition.
Patent NZ-719952-A (NZ)
Title: Pesticidal compositions and related methods
Inventor: BUYSSE ANN M
IPC: A01N43/647
Filed: 2014-10-17
Abstract: A pesticidal composition comprises a pyridine triazole compound of formula (I) or any agriculturally acceptable salt thereof, wherein R1, R2, R3, R4, R5, Z, and x are as described herein. A method of controlling pests comprises applying the pesticidal composition near a population of pests.
Patent NZ-721256-A (NZ)
Title: Arrangement and method for deep soil preparation
Inventor: MØRK SINDRE KJEANG
IPC: A01B79/00
Filed: 2015-01-07
Abstract: An arrangement for the deep strip tillage of a soil (2) is disclosed, in which a secondary working element (11) includes one or more working element sections (111), a first working element section (111a) exhibiting a larger working depth than a primary working element (10) in a working position. Each working element section (111a, 111b, 111c, 111d) comprises a share arrangement (112) arranged between plate-shaped first and second shanks (113a, 113b). The first and second shanks (113a, 113b) are attached to side edges (112a, 112b) of the share arrangement (112) and form borders between a loose-soil channel and a portion of the non-tilled soil, or each working element section (111a, 111b, 111c, 111d) of the share arrangement (112) form the desired width of the channel. There are further working element sections (111b, 111c, 111d) each exhibiting a larger working depth than the preceding working element section (111a, 111b, 111c). The working element sections (111a, 111b, 111c, 111d) exhibit a horizontal spacing, viewed rearwards from the first working element sections (111a) relative to the working direction (WD) of the secondary working element, and the centre lines of successive working element sections (111a, 111b, 111c, 111d) are arranged in the same plane. A method of establishing strip-shaped, deep loose-soil channels (23) in a soil (2) arranged for storing water and receiving part of the root system of a vegetation is disclosed as well.
Patent NZ-759145-A (NZ)
Title: Method and mixing device for controlling the introduction of a pulverulent material into a liquid for an inline mixing method
Inventor: TACKE LUDGER
IPC: B01F5/10
Filed: 2018-04-03
Abstract: The invention relates to a method for controlling the introduction of a pulverulent material (P) into a liquid (F) consisting of at least one component for an inline mixing method according to the preamble of claim 1 or the preamble of sub-claim 2 and to a mixing device for carrying out the method, said method and mixing device ensuring that the disadvantages of the prior art which have become known are prevented. This is achieved by a first method in that, among others, • the pulverulent material (P) is supplied in a discontinuous manner in pulses by means of a chronological sequence of metering pulses (i), each of which is characterized by a mass flow of the pulverulent material (ṁP), a duration of the metering pulse (Δt1), and a time interval between adjacent metering pulses (Δt2), • a time-dependent power consumption (l(t)) is ascertained which is proportional to a stirring and/or shearing and homogenizing power required for a temporarily available mixing product (M*), and • at the end of the time interval between adjacent metering pulses (Δt2) and in the event of a deviation of the time-dependent power consumption (l(t)) from the reference power consumption (lo) by more than a specified tolerance, either upwards or downwards, the duration of the metering pulse (Δt1) for the following metering pulse (i) is shortened in the first case and lengthened in the second case while maintaining the ratio (V = Δt1/Δt2).
Patent NZ-766931-A (NZ)
Title: Drying and grinding machine
Inventor: SAKATA KOJI
IPC: B02C13/288
Filed: 2019-02-13
Abstract: To improve operating efficiency of a dry grinding machine, the dry grinding machine includes a rotating shaft; a first blade that is rotationally driven by the rotating shaft; a grinding chamber that houses the first blade; a feed-in section that feeds material to be processed, which is transported by hot wind into the grinding chamber from a direction intersecting the rotating shaft; and a discharging section that is arranged on a side of the first blade opposite the feed-in section, in an axial direction of the rotating shaft, and discharges from the grinding chamber, along with the hot wind, the material to be processed that has been ground by the first blade while being dried by the hot wind fed in from the feed-in section. The grinding chamber has a rotating body shape centered on the rotating shaft, and has a portion where an inner diameter becomes larger closer to the discharging section in the axial direction, at least on the discharging section side of the first blade.
Patent NZ-768993-A (NZ)
Title: A Retaining Wall
Inventor: FAHEEM ISSA PASHA AGHA AL-SALEEM
IPC: E02D29/02
Filed: 2020-10-15
Abstract: It is known to use retaining walls to prevent soil or other types of earth from moving. Retaining walls may for example be used to keep the ground stable under or adjacent to buildings, roads, paths, terraced areas, parks or playing surfaces, etc. A problem with many known retaining walls is that they are undesirably expensive and labour intensive to construct. It is an object of preferred embodiments of the invention to go at least some way towards addressing the above problems. According to the invention there is a retaining wall 1 comprising pre-stressed cementitious columns 2, in each case having a lower end secured at or in the ground. Each column is prestressed by way of metallic strands 10 combined with metallic stirrups 11, wherein the stirrups are in contact with and encircle the strands. The wall has a series of cementitious planks 3 engaged with and extending between pairs of the columns 2. Each plank is reinforced by way of metallic tensioning strands 16 combined with metallic stirrups 17, wherein the stirrups are in contact with and partially encircle a pair of strands, the stirrups being at spaced intervals for reinforcing. There is a body of earth behind the planks that exerts pressure on the columns but is retained by the columns and planks.
Patent NZ-771318-A (NZ)
Title: Organ care solution for ex-vivo machine perfusion of donor lungs
Inventor: HASSANEIN WALEED
IPC: A61M16/00
Filed: 2012-04-13
Abstract: A method of flushing a donor lung prior to preservation on an organ care system (OCS). The method includes: flushing the donor lung ante-grade prior to excising the donor lung from the donor’s body with a first solution comprising a nutrient, a colloid, a buffer, magnesium sulfate anhydrate, and a nitrate; flushing the donor lung retrograde prior to excising the donor lung from the donor’s body with a second solution comprising the nutrient, the colloid, the buffer, the magnesium sulfate anhydrate, and the nitrate; excising the donor lung from the donor’s body; and placing the donor lung on the OCS.
Patent PT-100672-A (PT)
Inventor: WILLIAMS MICHAEL TREVELYAN
IPC: C07C233/14
Filed: 1992-07-09
Abstract: PCT No. PCT/EP92/01497 Sec. 371 Date Jan. 10, 1994 Sec. 102(e) Date Jan. 10, 1994 PCT Filed Jul. 3, 1992 PCT Pub. No. WO93/01162 PCT Pub. Date Jan. 21, 1993.The invention provides the substantially geometrically pure cis-stereoisomeric form of a compound of formula (I) and the substantially geometrically and optically pure cis-stereoisomeric form of a compound of formula (II):    <IMAGE>  (I)   <IMAGE>  (II)  wherein R1 is H or C1-C4 alkyl, together with processes for their preparation. The compounds are intermediates for the preparation of the antidepressant agent known as sertraline.
Patent PT-103172-A (PT)
Title: Trailed motorized cutter and silo feeder for grass includes a free wheel system for fail safe operation
Inventor: CUNHA AGOSTINHO VILACA DA
IPC: A01F29/06
Filed: 2004-07-19
Abstract: The trailed motorized cutter and silo feeder for grass has a free wheel system preventing mechanical breakdown. The machine cuts the grass to a prescribed length, and is highly versatile.
Patent PT-106007-A (PT)
Title: Painel compósito incombustível, à base de cimento portland, gesso e partículas de madeira
Inventor: NUNES ANGELA MARIA JESUS DE SEQUEIRA SERRA
IPC: B32B13/02
Filed: 2011-11-16
Abstract: O PRESENTE INVENTO DIZ RESPEITO A UM PAINEL COMPÓSITO DE MADEIRA E LIGANTES CIMENTÍCIOS, DE SUPERFÍCIES PLANAS, COM VÁRIAS COLORAÇÕES POSSÍVEIS. ESTE PAINEL É CONSTITUÍDO POR 35 A 85% CIMENTO PORTLAND CINZENTO OU BRANCO; 10 A 20% DE PARTÍCULAS DE MADEIRA RESINOSA DESCASCADA; 10 A 20% DE SULFATO DE CÁLCIO HEMI-HIDRATADO; 0 A 10% DE UM ACELERADOR DE SUPERFÍCIE; 1,5 A 6% DE SOLUÇÃO DE SULFATO DE ALUMÍNIO; 0 A 30% DE CARBONATO DE CÁLCIO; E 0 A 15% DE PIGMENTOS. A INVENÇÃO UTILIZA O PROCESSO DE PREPARAÇÃO PARA O PAINEL VIROC EXISTENTE, AJUSTADO AO NOVO MATERIAL. ESTE PAINEL PARA ALÉM DE SER MUITO RESISTENTE, COM ELEVADAS PRESTAÇÕES AO NÍVEL DA RESISTÊNCIA AO IMPACTO, À HUMIDADE, ÀS VARIAÇÕES TÉRMICAS, AO RUÍDO E AOS FUNGOS E OUTROS MICRORGANISMOS, CUMPRE COM TODOS OS REQUISITOS DA NORMA DE PRODUTO ASSOCIADA.
Patent PT-115407-A (PT)
Title: Estrutura protésica biofuncionalizada com arquitetura de núcleo-invólucro para reparação total ou parcial de tendões ou ligamentos humanos
Inventor: MARIA ASCENSÃO FERREIRA DA SILVA LOPES
IPC: A61F2/00
Filed: 2019-03-28
Abstract: A PRESENTE INVENÇÃO REFERE-SE A UMA ESTRUTURA FIBROSA BIOFUNCIONALIZADA COM UMA ARQUITETURA DE NÚCLEO/INVÓLUCRO PARA REPARAÇÃO PARCIAL OU TOTAL DE TENDÕES OU LIGAMENTOS HUMANOS. A ARQUITETURA BASEADA NUM SISTEMA DE NÚCLEO/INVÓLUCRO CONFERE À ESTRUTURA FIBROSA UM COMPORTAMENTO FÍSICO E MECÂNICO ESPECÍFICO QUANDO ESTA SOFRE CARGA MECÂNICA DE FORMA REPETIDA, COMO ACONTECE COM UM TENDÃO OU LIGAMENTO NATIVO EM USO CONSTANTE NO CORPO HUMANO. O NÚCLEO BASEIA-SE EM VÁRIOS SUBCOMPONENTES, NOMEADAMENTE ESTRUTURAS ENTRANÇADAS MONTADAS PARALELAMENTE, AS QUAIS SÃO ENCERRADAS POR UM INVÓLUCRO ENTRANÇADO. ALÉM DISSO, UMA BIOFUNCIONALIZAÇÃO SELETIVA DAS DUAS PARTES DA ESTRUTURA NÚCLEO/INVÓLUCRO PODE SER APLICADA A FIM DE MELHORAR SELETIVAMENTE OU EVITAR A ADESÃO DE CÉLULAS IN VIVO.
Patent PT-117620-A (PT)
Title: Sistema automático de abertura e fecho de abas de embalagem
Inventor: MICKAËL FREDON
IPC: B65D5/08
Filed: 2021-12-03
Abstract: A INVENÇÃO REFERE-SE A UM SISTEMA DE ABERTURA E FECHO AUTOMÁTICO DE ABAS DE EMBALAGENS FEITAS A PARTIR DE UMA LÂMINA DEFINIDA E CORTADA DE MATERIAL SEMIRRÍGIDO, COMPOSTA POR UM FUNDO OU BASE (1) DE CUJAS BORDAS LATERAIS EMERGEM FACES LATERAIS (2), UM PAINEL FRONTAL (3), UMA ABA DE FECHO (4), E UMA UNIÃO ARTICULADA EM FORMA DE FOLE (5), CARACTERIZADO POR O SISTEMA DE ABERTURA E FECHO INCLUIR UMA UNIÃO ARTICULADA EM FORMA DE FOLE (5) ENTRE, PELO MENOS, UMA ABA DE FECHO (4) DE UMA EMBALAGEM E UMA SECÇÃO LATERAL (3.1), ONDE A ABA DE FECHO (4) E A SECÇÃO LATERAL (3.1) EMERGEM UMA PELA PARTE SUPERIOR E A OUTRA LATERALMENTE DE UM PAINEL FRONTAL (3) ONDE A REFERIDA UNIÃO ARTICULADA (5) PERMITE, APENAS COM UM LIGEIRO EMPURRÃO NA DIREÇÃO DESEJADA, SER MANTIDA NA POSIÇÃO VERTICAL OU DE FECHO, ONDE A UNIÃO ARTICULADA EM FORMA DE FOLE (5) DEFINE UMA SUPERFÍCIE CONTÍNUA NA QUAL DUAS SUPERFÍCIES SÃO DEFINIDAS, UMA COM UM ÂNGULO ENTRE 30º E MENOS DE 45º E A OUTRA ENTRE 45º E 60º, SENDO O ÂNGULO DE TODA A SUPERFÍCIE CONTÍNUA DE PELO MENOS 90º.
Patent RU-94027687-A (RU)
Inventor: BERND KHUBER
IPC: C08F8/06
Filed: 1994-07-12
Abstract: FIELD: polymers. SUBSTANCE: product: acrylonitrile-base modified polymers adsorbing metal ions were proposed that were synthesized by: a) acrylonitrile-base polymer interaction with hydroxylamine or one of its derivative, or with a mixture of hydroxylamine and one of its derivative, and b) product treatment with oxidizing agent at the stage a). Acrylonitrile-base modified polymer can be used for treatment of sewage or water saturated with heavy metal ions. EFFECT: improved method of synthesis, enhanced effectiveness.
Patent RU-94030795-A (RU)
Inventor: LOSHKAREV G L
IPC: A23J1/18
Filed: 1994-08-17
Abstract: FIELD: food industry. SUBSTANCE: addition is suspension of inhibited yeast envelopes from wine-making production exhibiting negative electrokinetic potential 15-40 mv and specific surface 125-150 m/g. In the process of product making the yeast deposit from wine-making production is washed with drinking water, suspension is heated to 80-85 C, kept at this temperature for 3-4 hr, cooled to 35-40 C and preserved. EFFECT: improved method of addition making. 9 cl
Patent RU-94032111-A (RU)
Inventor: GUMEROV A G
IPC: E02B15/04
Filed: 1994-08-31
Abstract: FIELD: removal of oil from water surface. SUBSTANCE: oil-contaminated spot is covered with frame-supported cloth and, into closed space thus formed, a heat carrier, for example, hot air is supplied, whereas oil collection is effected with intake appliance mounted in the same space. Heat carrier used to heat oil product is returned into heating system to be recycled. Arrangement is provided with heat generator. Collection mechanism together with intake appliance can be displaced over polluted spot. Arrangement is intended to be employed preferably in cold season. EFFECT: enhanced efficiency of oil collection owing to preliminarily heating polluted spot. 3 cl, 3 dwg
Patent RU-94034749-A (RU)
Inventor: KIRIENKO A I
IPC: A61B5/02
Filed: 1994-09-12
Abstract: FIELD: medicine; vascular surgery. SUBSTANCE: method involves localization of the faulty valve by ultrasonic angioscanning, then ultrasonic angioscanning is performed in conditions of dosed compression on the lower extremity. Liquidation of the retrograde blood flow against the background of pneumatic compression is indicative of the need for extravasal correction. EFFECT: simpler and more reliable method.
Patent RU-94042553-A (RU)
Inventor: POPOV V I
IPC: H02K3/28
Filed: 1994-11-29
Abstract: FIELD: stator windings of multipole synchronous and induction machines. SUBSTANCE: three-phase fractional-slot (q=12/7) double-layer winding with pole number 2p=14 in slots z=72 has uniformly shifted coils at slot pitch yassembled into 6p=42 coil groups numbered 1G through 42G with coils grouped there in row 2 2 2 1 2 2 1 repeated six times. First phase has series-connected groups number 1G+(3c)G with differentially connected even-numbered groups relative to odd-numbered ones; two other phases have groups whose numbers alternate at intervals of 2p=14 and 4p=28 groups. Novelty is that first and second coils in two-coil groups have turn number (1-x)wand (1+x)wfor groups (1G+7C)G and 5G+(7C)G, (1-x)wfor each of groups 2G+(7C)G, (1+x)wand (1-x)wfor groups 3G+(7C)G and 6G+(7)G; coil of single-coil groups 4G+(7C)G and 7G+(7C)G have turn number (1+x)w, where y=6; k= 1,1, . ..,(2P-1); C=0,1,2,...,(p-2); 2•wis turn number per slot; parameter "x" is chosen within the range of 0,20≅ x≅ 0,35.. EFFECT: improved electromagnetic parameters of winding with fractional slot per pole per phase due to reducing its differential dissipation.
Patent RU-94043895-A (RU)
Inventor: GOMEL SKIJ M V
IPC: B29B17/02
Filed: 1994-12-13
Abstract: FIELD: reprocessing of used plastic and other components of objects. SUBSTANCE: apparatus has casing, drive mounted in casing and parallel rolls with projections positioned on roll surface. One of rolls is connected with drive. Projections are formed as interengageable teeth. Other roll is mounted for loose rotation on spindle fixed in rotary lever. Spindle is secured in casing. One arm of lever is spring-biased to casing and other arm is supported by restrictor screwed into casing. Casing has syringe ampule receptacle with slot for receiving movable knife, which is coupled with handle through lever and spindle. Handle is positioned outside casing. EFFECT: increased efficiency by preventing disposable medical used needles and syringes to be repeatedly used, wider operational capabilities and enhanced reliability in operation. 2 cl, 2 dwg
Patent RU-94044808-A (RU)
Inventor: PCHENTLESHEV V T
IPC: B64C29/04
Filed: 1994-12-21
Abstract: FIELD: aviation. SUBSTANCE: aeroplane is provided with lift-cruise jet engine mounted in nose fuselage along its longitudinal axis; engine has two swivel jet nozzles: one on port and one on starboard from fuselage. Engine nozzles are located in fuselage center. Aeroplane is also provided with lift jet engine located in rear fuselage along its longitudinal axis; jet nozzle of this engine is located on under side of center fuselage, thus lift- cruise jet engine and lift jet engines are located with their nozzles facing each other. EFFECT: enhanced reliability.
Patent RU-94045609-A (RU)
Inventor: DROBYSHEVSKIJ JU V
IPC: G21C5/00
Filed: 1994-12-30
Abstract: FIELD: nuclear energy engineering. SUBSTANCE: method includes neutrons slowing-down, their returning to fission zone and fuel composition circulation. Fuel composition has breeding material with isotopic elements of reproducing fission materials. Fuel composition circulation goes through fast neutrons area and thermal neutrons area of fission zone to cooling zone, besides, composition circulation means going by two ways, which one goes through thermal neutrons area to cooling zone, but another goes through fast neutrons area and cooling zone. Neutrons circulation means neutrons selective returning to thermal neutrons area of fission zone. Nuclear reactor for controlled fission has slowing-down material and fuel composition in closed circuit is distinguished by fuel composition placing in two circulation loops and both loops are connected by interchanging of fuel composition. Moderator is made like hollow device for thermal neutrons directed flow forming, device has channels directed towards fuel composition circuit crossing thermal neutrons area of fission zone only. EFFECT: deeper fuel burning. 8 cl