baber/WOPTO huggingface dataset:
Patent CA-2364893-A1 (CA)
Title: Recliner assembly having a shaft with an annular recess
Inventor: VILLARROEL RANDY
IPC: B60N2/235
Filed: 2001-12-10
Abstract: A recliner assembly for operatively interconnecting a seat back and a seat cushion allowing pivotal adjustment of the seat back relative to the seat cushion. The recliner assembly comprises an inner disc fixedly secured to the seat cushion and an outer disc fixedly secured to the seat back. The outer disc is rotatably nested within the inner dis and includes an annular rim of gear teeth extending radially inwardly. At least one pawl is adapted for lockingly engaging the annular rim of gear teeth on the outer disc and is disposed between the inner and outer discs. The pawl is radially moveable between a locked position, wherein the pawl is lockingly engaged with the annular rim of gear teeth on the outer disc, and an unlocked position, wherein the pawl is disengaged from the annular rim of gear teeth on the outer disc. A  biasing member extends between the pawl and the inner disc for biasing the pawl in the locked position. A cam shaft assembly is rotatably journaled to both of the inner and outer discs for actuating the pawl between the locked and unlocked positions.  The cam shaft assembly comprises a cylindrical shaft and a cam. The cylindrical shaft has proximal and distal ends. An annular shoulder is formed in the cylindrical shaft disposed between the proximal and distal ends and extending radially outwardly from the shaft. An annular recess formed in the annular shoulder. A ramped surface extends from the annular recess and tapers towards the proximal end. The cam has a center bore and a plurality of teeth extending radially inwardly from the bore. The cam has a hardness greater than that of the shaft. The cam is press fit onto the shaft and locating axially against the annular shoulder, such that material scraped from the shaft during assembly of the cam onto the shaft is displaced into the annular recess to ensure the proper alignment of the cam against the annular shoulder of the shaft.
Patent CA-2368047-A1 (CA)
Inventor: SCHOLS DOMINIQUE
IPC: A61P17/06
Filed: 2000-03-24
Abstract: La présente invention concerne une nouvelle classe de composés hétérocycliques se liant aux récepteurs de chimiokine et inhibant de ce fait la liaison de leurs ligands naturels. Ces composés ont un effet protecteur contre l'infection par VIH grâce à leur liaison aux récepteurs de chimiokine, y compris CXCR4 et CCR5, inhibant ainsi la liaison par ces chimiokines. La présente invention concerne un composé représenté par la formule (I) dans laquelle W désigne un atome d'azote et Y est absent ou W désigne un atome de carbone et Y = H ; R?1¿ à R?7¿ peuvent être les mêmes ou être différents et sont indépendamment sélectionnés entre un hydrogène ou un alkyle en C¿1-6? droit, ramifié ou cyclique ; R?8¿ représente un groupe hétérocyclique substitué ou un groupe aromatique substitué ; Ar représente un cycle aromatique ou hétéroaromatique chacun éventuellement substitué à une position unique ou à des positions multiples, non liantes par des groupes donneurs d'électrons ou des groupes suppresseurs ; n et n' désignent indépendamment 0 à 2 ; X désigne un groupe représenté par la formule (a) ou (b) dans lesquelles le cycle A désigne un cycle à 5 ou 6 chaînons saturé ou insaturé et éventuellement substitué et P désigne un atome de carbone éventuellement substitué, un atome d'azote éventuellement substitué, un atome de soufre ou un atome d'oxygène. Le cycle B désigne un cycle de 5 à 7 chaînons éventuellement substitué. Le cycle A et le cycle B de la formule précédente peuvent être reliés au groupe W à partir de n'importe quelle position en passant par le groupe V, V représentant une liaison chimique, un groupe en (CH¿2?)¿n''? (dans lequel n'' = 0-2) ou un groupe C=O. Z représente (1) un atome d'hydrogène, (2) un groupe alkyle en C¿1-6? éventuellement substitué, (3) un groupe alkyle en C¿0-6? substitué par un groupe aromatique ou hétérocyclique éventuellement substitué, (4) un alkylamino en C¿0-6? éventuellement substitué ou un groupe cycloalkylamino en C¿3-7?, (5) un groupe carbonyle ou un sulfonyle éventuellement substitué. Ces composés comprennent également n'importe quel sel d'addition acide acceptable du point de vue pharmaceutique de ces composés ainsi que leurs complexes métalliques et n'importe quelle forme stéréoisomère et mélange de formes stéréoisomères de ces composés.
Patent CA-2368352-A1 (CA)
Title: Method for treating neurodegeneration
Inventor: TAKASU YOSHIYUKI
IPC: A61K31/4015
Filed: 2001-02-23
Abstract: N-(2,6-dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl)acetamide is used for the preparation of medicaments, particularly of pharmaceutical compositions containing it as an active ingredient, for the treatment of neurodegeneration, in particular in post-stroke human patients. The early administration of nefiracetam in said pharmaceutical compositions after a stroke allows an improvement of the Activities of Daily Living and the recovery, or at least in improvement in the recovery of, the post-stroke patients.
Patent CA-2369848-A1 (CA)
Title: Human endogenous retrovirus in breast cancer
Inventor: GARRY ROBERT F
IPC: A61K35/76
Filed: 2000-06-30
Abstract: The present invention is related to mammary tumor virus (MTV). MTV represents a group of retroviruses which possess very high homology to mouse mammary tumor virus (MMTV), a virus known to cause neoplastic mammary disease in mice.  As described herein, MTV's have been identified in human, cat, and Rhesus macaque. The present invention specifically provides for recombinant nucleic acids and polypeptides derived from these MTV's as well as methods for using these biological molecules.
Patent CA-2370086-A1 (CA)
Title: Inverted board mounted electromechanical device
Inventor: MARTICH MARK E
IPC: H05K1/14
Filed: 2001-05-10
Abstract: A new board mounted electromechanical device (103) is provided that mounts to a relay substrate (122) to form a low profile reed relay (100). The reed relay (103) is electrically connected to the electrical contacts (128) via a signal traces (130) and additional electrical traces (130) located on the same side of the relay substrate (122) which connect to the relay's signal and shielding. Additional traces (130) on both sides of the signal traces of the reed relay (103) provide a co-planar wave guide to maintain the desired impedance of the signal path. The reed relay (103) is mounted in an inverted manner into a cut-out (134) in the main circuit board (132) so that the other portion of the reed relay (103) itself is sits within the cut-out (134) in the main circuit board (132). As a result, the reed relay component (103) is recessed below the surface of the main circuit board (132) resulting in an overall low profile circuit board.
Patent CA-2370459-A1 (CA)
Inventor: TRAVERT PIERRICK
IPC: G01M17/02
Filed: 2002-02-05
Abstract: The pneumatic vehicle tire has measurement patches at the tread, with embedded monitors, to register the adhesion of the tread against the road surface to give current road conditions and assist in driving. The pneumatic vehicle tire incorporates a monitoring patch (1) on the tread to measure the grip on the road surface. (1) has a center zone (10) and a surrounding zone (11). On functioning normally, the center zone slides along the road, while the tread has a non-slip action to give a measure of the maximum tire grip potential at any time from the center zone, through a monitor embedded in the tire structure to register at least the tangential force on the center zone. An Independent claim is included for a tire grip test, where an initial signal gives the tangential force at the center zone of the measurement patch to register a signal variation which shows a loss of adhesion. An estimate is produced of the friction potential at the contact surface of the center zone of the patch, to give an estimate of the adhesion potential of the tire tread.
Patent CA-2371022-A1 (CA)
Title: Genetically engineered oral commensal organisms as vaccines
Inventor: LEE SONG F
IPC: C07K14/235
Filed: 2000-04-21
Abstract: In accordance with the present invention, there are provided compositions comprising a live oral commensal bacteria, such as a streptococci, that has been genetically modified to express immunogenic fragment(s) of one or more pathogens, such as a mucosal pathogen like B. pertussis, which causes the disease known as whooping cough. The modified organisms are administered orally and/or intranasally. Once an infection of the modified commesal bacteria is established in the oral cavity of the host, the modified organism will continue to express the immunogenic pathogenic fragment(s) so long as the infection persists. Since such oral commensal bacteria generally persist in the oral cavity of humans and other susceptible vertebrates throughout life, the need for booster immunizations is minimized or reduced, providing the host protection against the pathogen throughout life. As native oral commensal organisms are spread from mother to infant as well as between adults by daily contact, invention compositions and methods will be particularly useful for providing immunity in undeveloped countries where conventional vaccines are too expensive to be effectively used.
Patent CA-2372551-A1 (CA)
Title: Improved structure and method for testing bond strength and/or removing integrated circuit devices bonded to substrates
Inventor: LANDREVILLE JEAN-LUC L
IPC: G01N33/00
Filed: 2002-02-18
Abstract: The present invention relates to methods and structures for facilitating the removal of integrated circuit devices, microelectronic devices or die from substrates and/or for testing the integrity of the bonding between such devices and the substrate, and preferably where the integrated circuit device is a flip chip. The invention provides. in one embodiment a microelectronic device or die having a ball and stud connector attached to a surface of the device opposite to the surface which is intended to be connected to a substrate. In other embodiments, the invention provides for methods and apparatus for removing one or more die attached to a substrate, or assessing the integrity of the bond between each die and the substrate. Each die having a ball and stud connector attached thereto is positioned or secured in a holder. A mechanism clamped to the ball and stud connector applies a tensile force to the die such that the tensile force is exerted essentially perpendicular to the surface of the substrate to which the die is attached and this results from the interaction of the mechanism and the ball and stud connector.  This results in removal of the die from the substrate without significant damage to the die or the substrate or for assessing the integrity of the bond between the die and the substrate by attaching a ball and stud connector to the die. No application of heat is required.
Patent CA-2373990-A1 (CA)
Title: Pyrrolotriazine inhibitors of kinases
Inventor: QIAN LIGANG
IPC: C07D487/04
Filed: 2000-05-16
Abstract: The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof. The formula (I) compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2, FGFR-1, PDGFR, HER-1, HER-2, thereby making themuseful as anti-cancer agents. The formula (I) compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
Patent CA-2377358-A1 (CA)
Inventor: PETTERSEN KETIL
IPC: D06C19/00
Filed: 1999-10-25
Abstract: Alliage de magnésium présentant une résistance améliorée à la corrosion et contenant magnésium 1,5-5 % en poids Al, 0,6-1,4 % en poids Si, 0,01-0,6 % en poids, Mn et 0,01-0,4 % en poids RE. Procédé servant à améliorer la résistance à la corrosion d'alliage de magnésium, d'aluminium, de silicium dans lesquels on ajoute M, de manière à limiter les impuretés de Fe, ce qui consiste à conserver un niveau bas de Mn et Fe par apport de quantités limitées de RE.
Patent CA-2377720-A1 (CA)
Inventor: OLSON DON B
IPC: B23P17/00
Filed: 2000-06-16
Abstract: A self-supporting, solid surface (SS) work surface (54) adapted to be installed atop a support structure is manufactured from one or multiple modules that are joined together to form a visually single SS work surface.  Each module (46) includes a centrally-disposed molded work surface have a bottom face and a top face, has a given thickness, and has at least a first edge and a second edge. A first molded edge portion is joined to the first edge and extends downwardly from the centrally-disposed molded work surface. A  molded second edge portion is joined to the second edge and extends upwardly from the centrally-disposed molded work surface.
Patent CA-2379776-A1 (CA)
Title: A device for spray dispensing a composition for topical application comprising vitamin e and essential fatty acids
Inventor: PANIN GIORGIO
IPC: A61K8/00
Filed: 2000-07-26
Abstract: A device for spray dispensing a composition for topical application comprisi ng a collapsible container (1) in turn enclosed in a spray bomb filled with a pressurized fluid, wherein said composition comprises: a) one or more volati le silicones, b) at least one component chosen among essential fatty acids, polyunsaturated .OMEGA.-6 or .OMEGA.-3 fatty acids and oils that contain the m and c) vitamin E.
Patent CA-2380135-A1 (CA)
Inventor: GELBARD RICHARD
IPC: G03B13/02
Filed: 2002-04-03
Abstract: A viewfinder for mounting on a camera having a video signal tap, such as a professional video camera, to extend forwardly and laterally of the camera. A pivotable member is connected to a support base for selectively pivoting about a laterally extending axis and being selectively locked in any angular position. A viewing module is releasably connected to the pivotable member to extend rearwardly along the side of the camera and has a CRT facing rearwardly with an eyepiece for viewing the CRT. The viewing module has controls for the CRT on an outwardly facing surface for manually adjusting the controls. Cooperating and releasable electrical connectors are provided between the pivot member and the viewing module for transmitting video signals and electrical power therebetween. An extension member, either of a fixed length or telescoping, may be installed between the pivot member and the viewing module and has the same electrical connectors.
Patent CA-2381343-A1 (CA)
Inventor: KIKUCHI TATSUO
IPC: H01T23/00
Filed: 2000-06-09
Abstract: L'invention concerne une cellule de décharge convenant pour un générateur d'ozone. Cette cellule de décharge comprend un premier ensemble d'électrodes (10) supérieure et inférieure formées de corps rigides plats, qui sont maintenues dans une position opposées l'une à l'autre au moyen de deux éléments (20) d'espacement intercalés entre les deux électrodes de manière qu'un espace est défini entre deux. Dans cet espace est installée une unité diélectrique présentant une structure rigide et comprenant une seconde électrode (32) intercalée entre deux plaques (31) de verre. Une pluralité d'éléments (40) d'espacement sont insérés entre l'unité (30) diélectrique et les premières électrodes (10) de sorte que l'unité (30) diélectrique peut être maintenue dans une position neutre à l'intérieur de l'espace et qu'un espace (50) de décharge est formé de chaque côté de l'unité. L'espace de décharge (G) peut avoir une largeur inférieure à 0,4 mm. Les composants de la cellule et les mécanismes de fixation sont ainsi protégées contre les dommages.
Patent CA-2382331-A1 (CA)
Title: Vaccine against intra-cellular pathogens
Inventor: COLACO CAMILO ANTHONY LEO SELW
IPC: A61K39/00
Filed: 2000-08-18
Abstract: The present invention relates to a method for producing and isolating specif ic immunogenic heat shock proteins induced by heat or tumour necrosis factor treatment of cells infected by intra-cellular pathogens; and vaccines prepar ed from such proteins.
Patent CA-2383545-A1 (CA)
Title: Wavelength division multiplexer/demultiplexer using homogeneous refractive index lenses and transmission grating
Inventor: WADE ROBERT K
IPC: G02B6/34
Filed: 2000-05-31
Abstract: A wavelength division multiplexing device (10) comprises a homogeneous refractive index collimating lens (16) for collimating a plurality of monochromatic optical beams (28), a mirror (18a), a diffraction grating (20), for combining the plurality of collimated, monochromatic optical beams into a multiplexed, polychromatic optical beam (30), and a homogeneous refractive index lens L (22) for focusing the multiplexed, output beam. The WDM is connected via coupling devices (14, 24) to optical fiber (12, 16) or active devices like photodiodes or lasers. In a preferred embodiment, the lenses are made of a material having a high refractive index to keep spherical aberrations low. The WDM may also contain additional boot lenses made of lower refractive index material.
Patent CA-2385156-A1 (CA)
Inventor: FROMENTAL-RAMAIN CATHERINE
IPC: G01N33/566
Filed: 1999-09-01
Abstract: The invention relates to methods of identifying agents that interact with retinoid X receptor dimers. The invention also relates to in vitro chromatin  based DNA template transcription systems.
Patent CA-2390679-A1 (CA)
Inventor: PARISE SERGIO
IPC: H04N7/10
Filed: 2002-06-14
Abstract: A system for self contained, low-power re-broadcast and reception of content signals at least contains a content signal transmitter adapted to transmit/re-broadcast a content signal which it has Frequency Modulated (FM), at least includes one receiver adapted to receive the FM content signal, a cable infrastructure with cables adapted for transmitting in-building content signals, and an antenna connected to a cable and placed in the effective range of the receiver, given predefined maximum antenna power limits (such as those defined by the Federal Communications Commission).    Consequently, receivers which do not have (or have available) coaxial cable jacks, or those which do have coaxial cable jacks but are not physically reachable by coaxial can still receive re-broadcast content signals. In the preferred embodiment, an automatic gain control (AGC) circuit is connected between the cable and the antenna to maintain the signal transmitted power level close to the allowable maximum, while not exceeding it.
Patent CA-2391713-A1 (CA)
Title: Whipstock and retrieval method and apparatus
Inventor: DEWEY CHARLES H
IPC: E21B47/09
Filed: 2002-06-25
Abstract: The retrieval tool includes a cylindrical member having a body, an inner passage, a guide cylinder and an engaging member. The engaging member may slide within the cylindrical member in order to engage a whipstock against an inner surface of the guide cylinder, facilitating removal of the whipstock from a borehole.  A actuating member, piston, retainer and swivel sub may be used to connect the engaging member to the retrieval tool and enhance the mobility of the engaging member within the cylindrical member. A spring may also facilitate locking engagement of the engaging member and whipstock. Contact between the retrieval tool and the whipstock may lead to an increase of pressure within the inner passage, such pressure increasing the engagement between the engaging member and whipstock.
Patent CA-2392703-A1 (CA)
Title: Human heparanase-related polypeptide and nucleic acid
Inventor: SIEMEISTER GERHARD
IPC: A61P29/00
Filed: 2000-12-18
Abstract: The present invention relates to newly identified polynucleotides, and polypeptides encoded by such polynucleotides, the use of such polypeptides, as well as the production of such polynucleotides and polypeptides. More particularly, a polypeptide of the present invention is a heparanase-related  endoglucuronidase. The invention also relates to vectors and host cells comprising a polynucleotide of the invention. Furthermore, the invention relates to antibodies directed to polypeptides according to the present invention and to pharmaceutical compositions and diagnostic reagents comprising such antibodies, polypeptides or polynucleotides. The invention further relates to a method of altering, modifying or otherwise modulating t he level of expression of the heparanase-related endoglucuronidase in a cell or  in a organism. A further aspect of the invention are assay systems suitable for identifying modulators, e.g. agonists or antagonists of such polypeptide s.
Patent CA-2393623-A1 (CA)
Title: Surface plasmon resonance
Inventor: PERKINS ELAINE ANN
IPC: G01N21/55
Filed: 2000-12-07
Abstract: The surface plasmon resonance apparatus (1) for detecting a soluble and/or particulate analyte comprises a prism sensor (2) providing a metallised sensor surface (3) capable of binding the analyte, and a laser (10) providing a beam (4) for direction at the sensor surface (3). A detector (5) is provided which is capable of detecting light (6), which is internally reflected from the sensor surface (3). Displacement means (7) comprising a vibrator (8) and mirror (9), is operable whereby the excitation beam (4) is displaced over an angular range (A) relative to the sensor surface (3). An analyte sample (15) is disposed on the metallic sensor (3). The detector (5) is used to interpret the light signals (6) internally reflected from the sensor surface (3) so that the sample (15) is analysed. A video camera system (16), which includes a mirror (17), microscope objective (18) and CCD (charge-coupled device) array (19), is used to detect the scattered light emitted from the upper face of the sensor surface (3).
Patent CA-2394950-A1 (CA)
Title: Three dimensional steerable system
Inventor: TRAINOR WILLIAM F
IPC: E21B47/01
Filed: 2000-12-14
Abstract: A steering assembly (20) includes upper (26) and lower (28) tubular housings connected by a universal joint (30). An angle cam (80) is dis-posed on the end of the lower housing and projects into the housing. A plurality of wedge members (90) extend axially from the upper housing and into engage-ment with the angle cam. Drive trains (150) are connected to the wedge members to move the wedge members toward and away from the angle cam to change the angle and azimuth of the lower housing with respect to the upper housing by the universal joint. The lower housing is connected to a bearing pack (16) sup-porting a drill bit (12) so as to change the direction of the drill bit. The steering assembly is connected to composite tubing (520) having conductors (584, 586) in the wall and a processor (514) is at the surface. Data on the position of the bit is transmitted to the processor to change the bend angle and direction of the drilling of the bit.
Patent CA-2396309-A1 (CA)
Title: Pneumatic nailer coiled collation strip
Inventor: GABRIEL WILLIAM L
IPC: F16B15/08
Filed: 2002-07-29
Abstract: A collation strip for use within a nail gun is fabricated from a suitable polypropylene composition and has a relatively large thickness dimension, however, in order to impart enhanced flexibility to the thickened collation strip, the collation strip is provided with a plurality of auxiliary apertures within its spine section, or alternatively within its spine and hinged sections. Such enhanced flexibility permits the collation strip to be utilized under relatively low temperature conditions such that the collation strip will not experience jamming within the nail gun.
Patent CA-2396934-A1 (CA)
Inventor: FARINE PIERRE-ANDRE
IPC: G04G3/04
Filed: 2000-12-07
Abstract: The invention concerns a device (1) comprising a mixer (4) producing a signa l (S4) having a frequency (F4) equal to the difference between two frequencies  (F2, F3) which are those of the two signals (S2, S3) each produced by a generator (2, 3) and which vary parabolically depending on the temperature ( T) with quadratic coefficients (.beta.1, .beta.2) different from each other. In  order to make the frequency (F4) of the signal (S4) produced by the mixer (4 ) at least substantially independent of temperature (T), the generators (2, 3)  are so designed that the relationship of the quadratic coefficients (.beta.1 , .beta.2) is equal to the inverse relationship of the values (F2r, F3r) which  the corresponding frequencies (F2, F3) have at a predetermined temperature (Tr).