baber/WOPTO huggingface dataset:
Patent JP-4031028-B2 (JP)
IPC: C12Q1/6881
Filed: 1994-03-07
Granted: 2008-01-09
Abstract: PCT No. PCT/EP94/00654 Sec. 371 Date Oct. 23, 1995 Sec. 102(e) Date Oct. 23, 1995 PCT Filed Mar. 7, 1994 PCT Pub. No. WO94/21818 PCT Pub. Date Sep. 29, 1994The invention relates to a method for typing or subtyping one or more HLA-B alleles characterized by the sequence GCCA at position 30 to 33 of exon 2 (with said numbering being according to Zemmour and Parham, 1992), liable to be present in a sample, with said method comprising at least the following steps: (i) amplifying HLA-B alleles with at least one 5' end amplification primer selected from the following list: 5' -AGGTATTTCTACCCGCCA-3' (B25P) or sequence variants thereof, in combination with an appropriate 3' end primer being chosen from the same alleles as the above defined 5' end primers, with said 5' and 3' end primers being possibly labelled; and, (ii) hybridizing the amplified product, being labelled during or after amplification, at appropriate conditions with one or more suitable probes selected from region 15 to 261 of the HLA-B exon 2 region, with said numbering being according to Zemmour and Parham 1992, (iii) washing at appropriate washing conditions, (iv) detecting the hybrids formed; and, (v) inferring the allele present from the observed hybridization pattern.
Patent JP-3798427-B2 (JP)
IPC: C07C227/18
Filed: 1995-03-13
Granted: 2006-07-19
Abstract: The invention relates to DL-hydroxyphenylamino acid esters of formula    <IMAGE>  (1)  wherein n is 3 to 12 and m is 2 or 3. The compounds are useful as therapeutic agents having antiinflammatory, analgesic, antiallergic and antiasthmatic properties, and also as cosmetic compositions.
Patent JP-3388753-B2 (JP)
IPC: G01N33/76
Filed: 1996-03-22
Granted: 2003-03-24
Abstract: Water soluble hybrid phthalocyanine derivatives useful in competitive and noncompetitive assays immunoassays, nucleic acid and assays are disclosed and claimed having (1) at least one donor subunit with a desired excitation peak; and (2) at least one acceptor subunit with a desired emission peak, wherein said derivative(s) is/are capable of intramolecular energy transfer from said donor subunit to said acceptor subunit. Such derivatives also may contain an electron transfer subunit. Axial ligands may be covalently bound to the metals contained in the water soluble hybrid phthalocyanine derivatives. Ligands, ligand analogues, polypeptides, proteins and nucleic acids can be linked to the axial ligands of the dyes to form dye conjugates useful in immunoassays and nucleic acid assays.
Patent JP-4359859-B2 (JP)
IPC: A61P15/16
Filed: 1997-04-24
Granted: 2009-11-11
Abstract: The present invention relates to novel compounds of general formula (I) which can be used for treating medical disorders resulting from a deficiency in growth hormone.
Patent JP-3983811-B2 (JP)
IPC: H04B17/00
Filed: 1997-09-23
Granted: 2007-09-26
Abstract: The present invention is a method and apparatus for providing a received signal quality metric which is optimally designed to control the transmission power of a transmitter in a closed loop power control system. The present invention is described in the context of a spread spectrum communication system but it is equally applicable to other types of communication systems. In the present invention, the power control system is described for controlling the power of transmissions from a base station to a mobile station, referred to as forward link transmissions.
Patent MD-2750-B2 (MD)
Title: Piston liquid meter
Inventor: MOROYANU GEORGE
IPC: G01F11/00
Filed: 2000-03-24
Abstract: The invention relates to the mechanical engineering and is meant for liquid metered pouring out into vessels. The piston liquid meter includes an external cylinder and a rotary internal cylinder, coaxially placed therein, into the bases and lateral walls of which there are made inlet and outlet ports, correspondingly, which overlap by turns. The regulating cover is mounted onto the external cylinder by means of a threaded connection. The piston is placed into the cavity of the internal cylinder. With the piston it is joined a rod, freely installed into the central duct of the hollow shaft, rigidly fixed in the upper part of the internal cylinder and into the regulating cover. The free end of the rod is joined by means of a link with the driving shaft, which is kinematically joined with the transmission mechanism, the driving member of which is mounted onto its shaft, coupled with the driving shaft by an electromagnetic clutch, and the driven one is mounted onto the hollow shaft. The meter is additionally provided with a mechanism for regulating cover displacement, which contains a reversible electric motor, a gear-wheel joined with it, which engages into mesh with the gear ring, made onto the lateral outer surface of the regulating cover, and a dip stick, mounted onto a calibrated rule and coming in contact with the lower part of the regulating cover. The transmission mechanism is made in the form of a Maltese-cross movement. The four inlet ports, made into the base of the internal cylinder, are uniformly placed round a circumference, and the four outlet ports, made into its lateral wall, are uniformly placed between them and are misaligned about the inlet ones at an angle of 45o.
Patent ES-2200700-B2 (ES)
Title: Tablero tipo sandwich.
Inventor: DEL RIO CARBAJO MARCOS
IPC: B32B27/08
Filed: 2002-07-19
Granted: 2005-10-01
Abstract: Tablero tipo sandwich, de los que constan de varias capas sucesivas y presentan al exterior como cara y/o contracara un film de un polímero de naturaleza acrílica transparente al que se le ha añadido un termoplástico transparente insoluble, o poco soluble, en los disolventes orgánicos y presentando los films superficiales de la cara y contracara similares coeficientes de dilatación térmica, coeficiente de absorción de humedad y gramaje. De aplicación en el campo de la construcción.
Patent ES-2345644-B2 (ES)
Title: Columna de vacio de destilacion de aceite con placa de vaina engrosada en la zona de entrada tangencial de vapor en lugar de un revestimiento interior de acero inoxidable.
Inventor: GREEN ALAN W
IPC: B01D3/10
Filed: 2006-07-26
Granted: 2011-06-13
Abstract: Columna de vacío de destilación de aceite con
placa de vaina engrosada en la zona de entrada tangencial de vapor
en lugar de un revestimiento interior de acero inoxidable. La
columna de vacío (10) para la destilación de aceite incorpora una
placa de vaina engrosada (50) que tiene una placa de envainado (52)
que es más gruesa que el envainado (44) de un tramo o sección (40)
de columna adyacente. El uso de placas de vaina engrosadas (50),
unidas por explosivo o por laminación con rodillos, puede
proporcionar un mejor servicio que los revestimientos interiores
convencionales soldados por puntos o que las placas de carcasa
convencionales con capas superpuestas de soldadura.
Patent ES-2599357-B2 (ES)
Title: Planta termoeléctrica de tres ciclos rankine y una turbina de expansión directa cuyo foco frio procede de la regasificación del gas natural licuado
Inventor: FERREIRO GARCIA RAMÓN
IPC: F01K25/08
Filed: 2015-07-31
Granted: 2017-06-28
Abstract: La presente invención denominada "planta termoeléctrica de tres ciclos Rankine y una turbina de expansión directa cuyo foco frio procede de la sificación de gas natural licuado", es el aprovechamiento del proceso de regasificación del GNL para ser utilizado como foco frio de una planta termoeléctrica. Está constituida por tres ciclos Rankine y una turbina de expansión directa de GN, conectados a un generador eléctrico par medio de un eje. Esta planta es alimentada con calor procedente tanto de la industria como del entorno ambiental basado en agua de mar, ríos, lagos o aire del ambiente. Los ciclos Rankine operan con argón, metano y metano (o R14) respectivamente, mientras que la turbina de expansión directa de GN opera con el gas natural (GN) regasificado y destinado al consumo.
Patent IE-S86763-B2 (IE)
Title: System for control and amplification of inertia by means of a pilot synchronous compensator and electrically stored energy converter
Inventor: RICHARD MCGRATH
IPC: H02P9/00
Filed: 2015-04-17
Abstract: This invention relates to the enhancement of simulated/synthetic inertia systems to respond naturally to a frequency disturbance event by measuring and amplify the real inertial response of a pilot scale grid connected synchronous compensator (1), using a converter (4,9) fed by electrically stored energy sources (5,10). This solution eliminates difficulties with frequency measurement, harmonic distortion of waves, complexity of algorithm, and ensures that the stored energy feeding onto the converter can only be released in proportion to the natural, real inertial response of the pilot synchronous compensator. <Figure 1>
Patent IE-S86993-B2 (IE)
Title: Drugs intermediates 2-ethylhexanoic acid synthesis method
Inventor: YIDA YAN
IPC: C07C51/00
Filed: 2018-04-03
Abstract: Drugs intermediates 2-ethylhexanoic acid synthesis method, comprises the following steps: 3 mol 1-amino-2-bromo-3-ethylheptene, 4-5 mol dimethyl fumarate solution were added to the reaction vessel, controlled the stirring speed at 130-160 rpm, raised the temperature of the solution to 40-48°C, reacted for 2-3 h, washed with potassium nitrate solution for 4-6 times, adjusted the pH to 3-4 with potassium hydrogen sulfate solution, after the solution layered, extracted 5-7 times by 1,3-propanediamine solution, extracted 6-9 times by propylene glycol methyl ether solution, recrystallized from N-propylaniline solution, obtained 2-ethylhexanoic acid.
Patent AU-2001256461-B2 (AU)
Title: Immunotherapeutic methods and compositions
Inventor: DOBBIE JAMES
IPC: C12N5/0786
Filed: 2001-03-26
Granted: 2005-06-30
Abstract: This invention relates to methods and compositions introducing chemical entities into antigen presenting cells. The resulting presentation of said antigens on the surface of the antigen presenting cells gives an effect on the immune system. The invention also relates to the resulting modified antigen presenting cells and pharmaceutical compositions containing these cells. The invention discloses new understandings in adjuvancy and adjuvant preparations, including a series of related peptides and phospholipid vesicles incorporating said peptides.
Patent AU-2002224542-B2 (AU)
Title: Two-wheeled vehicle trailer
Inventor: WITSCHI CHRISTOPHE
IPC: B62K27/14
Filed: 2001-07-18
Granted: 2005-01-13
Abstract: The invention concerns a trailer (21) for a two-wheeler comprising means for being secured (22) on the vehicle, said securing means (22) are arranged in the form of a clamp with two arms (24) whereof the front ends (25) are designed to co-operate with the ends (26) of the rotation shaft of the vehicle rear wheel (23), and said trailer comprises means for clamping (28) said arms (24) adapted to maintain the front ends (25) of said arms (24) engaged with the ends (26) of the rotation shaft of the two-wheeler rear wheel (23).
Patent AU-2002257524-B2 (AU)
Title: Igniter with a safety device for a projectile which is shot from a pipe with angular momentum
Inventor: HAESELICH DETLEF
IPC: F42C15/26
Filed: 2002-03-12
Granted: 2006-05-18
Abstract: The igniter comprises a disk-shaped element ( 15 ) with a central portion ( 16 ) and a boundary portion ( 17 ) surrounding it for interrupting and/or releasing an ignition chain ( 13 a , 13 b) of the igniter. Only the central portion interrupts the chain of ignition and is supported by a holding device ( 19 ). A collecting space is provided around the holding device which, seen in the direction of flight of the projectile, is located below the boundary portion ( 17 ). The central portion ( 16 ) and the boundary portion ( 17 ) are connected with each other by means of a rated breaking point ( 18 ). Upon the initial acceleration of the projectile the boundary portion ( 17 ) is sheared off from the central portion ( 16 ) and received in the collecting space ( 21 ), whereupon the central portion ( 16 ) is also subsequently removed from the ignition chain ( 13 a , 13 b) by the twist of the projectile.
Patent AU-2002259325-B2 (AU)
Title: Aquarium filter system
Inventor: AXELROD GLEN S
IPC: B01D35/027
Filed: 2002-06-03
Granted: 2007-07-19
Abstract: An aquarium filter system comprising a pump, a manually positionable valve assembly, and one or a plurality of interchangeable filter cartridges. The filter cartridges are interchangeable and replaceable without the need to suspend water flow. The filter cartridges may be readily repositioned relative to their location from the pump. In method form, a method of changing filter cartridges in an aquarium filter is disclosed. The method comprises supplying a pump and pumping water to provide a continuous flow of water from the aquarium to one or a plurality of removable filter cartridges. This is followed by isolating any one or plurality of the filter cartridges from the flow of water and replacing any one or plurality of filter cartridges with one or a plurality of unused filter cartridges. This is all accomplished under conditions such that the continuous flow of water is uninterrupted.
Patent AU-2002328402-B2 (AU)
Title: Carba-sugar amine derivatives and treatments for disorder of glycolipid metabolism containing the same as the active ingredient
Inventor: OGAWA SEIICHIRO
IPC: A61P3/06
Filed: 2002-09-02
Granted: 2008-06-12
Abstract: Carba-sugar amine derivatives of formula (2) for treating a glycolipid metabolic disorder:   
wherein R 7  represents an alkyl group or an alkoxyalkyl group having an alkyl glycerol-derived backbone as shown by the following formula (3)   
or an acyloxyalkyl group having an acyl glycerol-derived backbone (in the following structural formula, each of 1 and m is independently an integer of from 0 to 18, each of X independently represents a methylene group or a carbonyl group) and each of R 8 , R 9 , R 10  and R 11  is a hydroxyl group.
Patent AU-2002348259-B2 (AU)
Title: High pressure gas processing configurations and methods
Inventor: NIELSEN RICHARD D
IPC: B01D53/40
Filed: 2002-11-25
Granted: 2007-03-15
Abstract: Contemplated plants comprise an acid gas removal unit that receives a compressed gas from an injection gas compressor, wherein acid gas is removed from the compressed gas in the acid gas removal unit at a pressure approximately above pipeline pressure.
Patent AU-2002363339-B2 (AU)
Title: Stable liquid pharmaceutical formulation of IGG antibodies
Inventor: KAISHEVA ELIZABET A
IPC: A61P37/06
Filed: 2002-11-08
Granted: 2008-02-07
Abstract: This invention is directed to a stable liquid pharmaceutical formulation comprising a high concentration, e.g. 50 mg/ml or more, of antibody in about 20-60 mM succinate buffer or 30-70 mM histidine buffer, having pH from about pH 5.5 to about pH 6.5, about 0.01-0.1% polysorbate, and a tonicity modifier that contributes to the isotonicity of the formulation. This liquid formulation is stable at refrigerated temperature (2-8° C.) for at least 1 year, and preferably 2 years. This liquid formulation is suitable for subcutaneous injection. The preferred antibodies include Daclizumab, a humanized anti-IL-2 receptor monoclonal antibody; HAIL-12, a humanized anti-IL-12 monoclonal antibody; HuEP5C7, a humanized anti-L selectin monoclonal antibody; and Flintozumab, a humanized anti-gamma interferon monoclonal antibody.
Patent AU-2003216643-B2 (AU)
Title: Method for interpretation of a radio-electrical command
Inventor: MARTY JACQUES
IPC: G01S3/02
Filed: 2003-04-11
Granted: 2009-07-09
Abstract: The order transmission system has an RF order transmitted towards a receiver. The receiver determines whether the RF order comes from a near zone or far zone. A command is executed as a function of the order received, only operating from instruction in the near zone.
Patent AU-2003218905-B2 (AU)
Title: Method of operating a fuel cell
Inventor: AHMED KHALIQ
IPC: H01M8/04223
Filed: 2003-04-22
Granted: 2008-05-08
Abstract: A method of generating hydrogen for use in a fuel cell system, which comprises processing a fuel which is essentially free of organic sulfur-containing compounds to produce a hydrogen-containing stream.
Patent AU-2004286229-B2 (AU)
Title: Control rod mechanism and system
Inventor: TOTI ANDREW J
IPC: F16C/
Filed: 2004-10-21
Granted: 2011-05-12
Abstract: A reversible control rod mechanism adapted for selectively and repeatedly rotating a shaft bidirectionally and thereby moving an attached load bidirectionally.
Patent AU-2005202673-B2 (AU)
Title: Pharmaceutical preparation of recombinant factor VIII lyophilized without albumin as a stabilizer
Inventor: PAIK SANG-HOON
IPC: A61K38/37
Filed: 2005-06-20
Granted: 2007-05-17
Abstract: Disclosed is a lyophilized preparation of recombinant factor VIII used as a therapeutic preparation of hemophilia A. The lyophilized preparation of recombinant factor VIII is prepared by performing lyophilization using a mixture comprising 6 to 100 mM of L-arginine, 3.5 to 50 mM of L-isoleucine, and 10 to 100 mM of L-glutamic acid as a stabilizer for stabilizing the recombinant factor VIII which exhibits an unstable activity during lyophilization, rather than using human blood derived albumin.
Patent AU-2005221862-B2 (AU)
Title: Metal implants
Inventor: PICKFORD MARTIN EDWARD LEE
IPC: A61L27/32
Filed: 2005-03-03
Granted: 2010-03-18
Abstract: A metal implant for use in a surgical procedure is provided with a surface layer that is integral with the metal substrate, and which incorporates a biocidal material. The surface layer is grown by anodizing at a voltage between 50 and 150 V, and the biocidal material incorporated in it by ion exchange. This produces a significantly harder surface than anodizing at low voltage, and generates pits containing ion-absorbing material.
Patent AU-2005240757-B2 (AU)
Title: Device and method for detecting molecular interactions
Inventor: BICKEL RALF
IPC: G01N21/64
Filed: 2005-05-06
Granted: 2011-02-03
Abstract: Device (A) for qualitative and/or quantitative detection of molecular interactions between probes (P) and target molecules (B) comprises (a) a microarray, i.e. a substrate with P immobilized on array elements, on a first surface and (b) a reaction chamber formed between the first surface and a second surface, where the spacing between the two surfaces can be varied. An independent claim is also included for a method for qualitative and/or quantitative detection of molecular interactions between probes (P) and target molecules (B) by adding a (B)-containing sample to the reaction chamber of (A) then detecting any interaction with immobilized (P).
Patent AU-2005247466-B2 (AU)
Title: System and method for playing a role-playing game
Inventor: KANE STEVEN N
IPC: A63F3/00
Filed: 2005-05-25
Granted: 2011-09-29
Abstract: A method and apparatus for playing role-playing game is provided that involves wagering. In one example game, players subscribe to multiple game sessions and eliminate other players to become the sole survivor of the game. The players may accrue points by eliminating other players. Further, players may eliminate other players in a combat environment.
Patent AU-2005270068-B2 (AU)
Title: C-Met modulators and method of use
Inventor: BANNEN LYNNE CANNE
IPC: C07D471/04
Filed: 2005-07-01
Granted: 2012-04-19
Abstract: The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. More specifically, the invention provides appropriately functionalized 5,6-fused bicyclics which inhibit, regulate and/or modulate kinase receptor, particularly c-Met, KDR, and flt-3, signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions.
Patent AU-2006201670-B2 (AU)
Title: Production of whole grain shredded products
Inventor: KARWOWSKI JAN
IPC: A23L19/18
Filed: 2006-04-21
Granted: 2011-09-29
Abstract: PRODUCTION OF WHOLE GRAIN SHREDDED PRODUCTS Shredded whole grain products, such as ready-to-eat cereals, and sweet and savory snacks, such as whole gmin shredded corn chips are continuously produced by pelletizing agglomerates of cooked, tempered, whole cereal grain particles. Cooked whole grains, such as corn and other non-gluten or low-gluten containing grains have a tendency to become hard and rubbery after cooking during the cooling and tempering process. The pelletization results in the production of whole grain pellets having a soft, pliable texture, which are shreddable into continuous net-like sheets on a mass production basis. The pelletizing may be at a pressure of about 200 psig to about 600 psig, preferably from about 400 psig to about 500 psig. The pelletizing temperature maybe controlled to provide a pellet temperature of about 80*F to about 120*F, preferably from about 90*F to about I 10*F, upon exiting the pelletizer. KFHI-120 (42905)
Patent AU-2006226764-B2 (AU)
Title: Lightweight concrete compositions
Inventor: WILLIAMS MICHAEL T
IPC: C04B28/02
Filed: 2006-03-22
Granted: 2010-06-24
Abstract: A lightweight concrete composition containing from 10 to 90 volume percent of a cement composition, from 10 to 90 volume percent of particles having an average particle diameter of from 0.2 mm to 8 mm, a bulk density of from 0.03 g/cc to 0.64 g/cc, an aspect ratio of from 1 to 3, and from 0 to 50 volume percent of aggregate; where the sum of components used does not exceed 100 volume percent, and where after the lightweight concrete composition is set it has a compressive strength of at least 1700 psi as tested according to ASTM C39 after seven days. The concrete composition can be used to make concrete masonry units, construction panels, road beds and other articles.
Patent AU-2006270420-B2 (AU)
Title: Automobile panel repair laminate
Inventor: CLEMENTS GEORGE J
IPC: C09J7/22
Filed: 2006-07-06
Granted: 2011-02-24
Abstract: Automobile panel repair laminates include a pressure sensitive adhesive bonded to a support backing. The support backing may be constructed of various materials such as plastically deformable polymeric materials including thermoplastic or thermoset materials and may have various thicknesses depending upon the desired conformability and rigidity necessary for the repair. The support backing may be bonded to the pressure sensitive adhesive by applying adhesion promoters such as solvents. The repair laminate is applied to a back or non-aesthetic side of the automobile panel, and the front side is repaired using standard techniques for filling and finishing.
Patent AU-2006273330-B2 (AU)
Title: Sterilizer selective to cariogenic bacterium, and method for sterilization of cariogenic bacterium
Inventor: SUGAI MOTOYUKI
IPC: A61Q11/00
Filed: 2006-07-25
Granted: 2012-02-09
Abstract: The bacteriolytic effect of a bacterial cell wall lytic enzyme can be increased by the addition of a surfactant to the enzyme. As a result, the time required for the lysis of a cariogenic bacterium with a bacterial cell wall lytic enzyme can be shortened, and the practical utility of a bacterial cell wall lytic enzyme (e.g., automutanolysin) as a prophylactic or therapeutic agent for dental caries can be improved.