baber/WOPTO huggingface dataset:
Patent CA-2606025-A1 (CA)
Title: Method for improving pharmacokinetics of protease inhibitors and protease inhibitor precursors
Inventor: STRANIX BRENT RICHARD
IPC: A61K31/135
Filed: 2006-04-26
Abstract: The present invention provides methods for improving the pharmacokinetics of protease inhibitors and protease inhibitor precursors and pharmaceutical composition comprising protease inhibitors or protease inhibitor precursors of formula I and a cytochrome P450 monooxigenase inhibitor; Formula (I) when the compound of formula I comprises an amino group, pharmaceutically acceptable ammonium salts thereof, wherein R1 may be, for example, (HO)2P(O)-, (NaO)2P(O)-, alkyl- CO- or cycloalkyl-CO-, wherein X may be, for example, F, CI, and Br, and wherein R2 and R3 are as defined herein.
Patent CA-2606656-A1 (CA)
Title: Locator and closure device and method of use
Inventor: GINN RICHARD S
IPC: A61B17/00
Filed: 2006-04-24
Abstract: The present invention is directed to a device (100) which is capable of both locating a punctured blood vessel wall and sealing the puncture in the vessel . In one embodiment, the device includes an elongate deployment member (7) having a sealing element (160) releasably disposed within a distal end thereof, said deployment member being coupled to a first actuator (8) configured to retract said deployment member relative to said sealing element, and an elongated indicator member (6) having a proximal end and a distal end, said indicator member extending through a lumen in said deployment member such that the distal end of said indicator member extends distally of the distal end of the deployment member, and said indicator member being coupled to a second actuator (2) configured to retract said indicator member relative to said deployment member.
Patent CA-2607613-A1 (CA)
Inventor: HAEMHOUTS PAUL D
IPC: A01G9/14
Filed: 2006-04-19
Abstract: Disclosed are light transmissive panels in general and, in particular, extruded multi-walled thermoplastic sheet structures having corrugated shaped wall(s) and/or surface(s) for use as roof and wall elements in greenhouses, said sheet structures having increased light transmission with combination of improved durability, good insulating properties and reduced maintenance requirements.
Patent CA-2609062-A1 (CA)
Title: Oligonucleotides or their functional homologues, a composition comprising the same and a method of treating b cell neoplasm
Inventor: YU YONG-LI
IPC: A61K31/7088
Filed: 2006-02-13
Abstract: The invention provides nine oligonuleotides with sequences of SEQ ID NO: 1-9 or their functional homologues or a composition comprising the same and a method for treating B cell neoplasm by using the oligonuleotides or their functional homologues or the composition comprising the oligonuleotides. The oligonuleotides induce the apoptosis of B cell neoplastic cells, up-regulate CD40 on B cell neoplastic cells and stimulate the production of IL-10 from B  cell neoplastic cells.
Patent CA-2609181-A1 (CA)
Inventor: LEE JAMES
IPC: A47B96/06
Filed: 2007-11-01
Abstract: A bracket for securing a shelf to a frame includes a body portion having an opening to receive a first segment of a U-shaped shelf support member and a body channel on a surface to receive a second segment of the U-shaped shelf support member. The bracket can be used in a shelving system having a shelf mounted between a left and a right frame each having one or more mounting holes along a vertical length to receive the bracket. When the bracket is mounted to the frame, the opening and the channel are aligned substantially parallel to a vertical axis of the frame.
Patent CA-2609730-A1 (CA)
Title: System, method, and article of manufacture for multi-player gaming from an off-site location
Inventor: ANGELL ROBERT CHARLES
IPC: G07F17/32
Filed: 2006-05-23
Abstract: A system, method, and article of manufacture are disclosed that comprise receiving, from one or more client terminals, two or more purchase requests, wherein each of the purchase requests identifies a wager for one or more multi-player games. A wager result is then determined for each wager at the time of purchase and stored in a database. Once all the wagers for an instance of a game are received, an outcome, such as a set of cards, is determined for each player and, if appropriate, the house (the host of the game). The outcome for each player is based on the previously determined wager result(s) and the type of game played. The outcome(s) are then stored with the wager(s) and wager result(s) in a transaction history file corresponding to each of the game's patrons (players) and in a game status file. A patron may then submit a request at a client terminal to reveal the results of the wager(s) and, optionally, the outcome of the game at either the gaming facility where the wagers were placed or at an off-site location.
Patent CA-2611147-A1 (CA)
Inventor: BUCHTA RICHARD
IPC: A61K31/203
Filed: 2006-05-26
Abstract: A pharmaceutical aerosol foam composition, comprising an effective amount of a pharmaceutically active ingredient, wherein said pharmaceutically active ingredient is a vitamin or analogue thereof; an occlusive agent; an aqueous solvent; an organic co-solvent; wherein the pharmaceutically active ingredient is insoluble in both water and the occlusive agent; and the occlusive agent being present in an amount sufficient to form an occlusive layer on the skin, in use. The pharmaceutically active ingredient can be selected from vitamin D3 and vitamin A and/or their analogues such as calcipotriene, tretinoin, acitretin, etc. In a second embodiment, an oil-in-water emulsion having a vitamin; an occlusive agent; an aqueous solvent; and an organic co-solvent, wherein the occlusive agent is present in an amount sufficient to foam an occlusive layer on the skin. The composition can be used to treat dermatological disorders such as psoriasis.
Patent CA-2611592-A1 (CA)
Inventor: SPENCER ALLAN HARVEY
IPC: A61P35/00
Filed: 2006-06-16
Abstract: There is provided a liquid pharmaceutical formulation for parenteral administration comprising: docetaxel or a pharmaceutically acceptable salt thereof; one or more glycols; and a pharmaceutically acceptable nonaqueous solvent system; wherein the formulation has a pH meter reading in the range of from 2.5 to 7.
Patent CA-2612794-A1 (CA)
Title: Transglutaminase mediated conjugation of growth hormone
Inventor: JOHANSEN NIELS LANGELAND
IPC: C07K14/61
Filed: 2006-06-15
Abstract: A method for PEGylating growth hormone, said method comprising reacting growth hormone with an amine comprising nucleophile which further comprises a first functional group in the presence og TGase to form a transaminated growth hormone, followed by a reaction of said transaminated growth hormone with a PEG which has been functionalised with a second functional group, wherein said first and second functional groups are selected so that they react to form a covalent bond.
Patent CA-2613144-A1 (CA)
Title: Osteosynthesis plate comprising through-openings which are inclined in relation to the plane of the plate
Inventor: JACOBS FRED J
IPC: A61B17/80
Filed: 2006-06-30
Abstract: The invention relates to an osteosynthesis plate (10) for treating fractures of the jawbone. Said plate has a plane and two plate sections (12, 14) which extend essentially inside the plane of the plate and are inclined or staggered in relation to each other. Said plate sections have associated longitudinal axes (16, 18). Through-openings (20, 22) which are inclined in relation to the plane of the plate are formed in both plate sections. The angular orientations of the through-openings inside the plane deviate in relation to a longitudinal axis (16) used as a reference straight line, by less than approximately 60~.  When the plate is used in the region of the jawbone, said small deviation of the angular orientations enables the osteosynthesis plate to be intraorally fixed. In this way, a transbuccal access through the cheek is not required.
Patent CA-2616015-A1 (CA)
Inventor: BOWLER MICHAEL
IPC: G06F12/00
Filed: 2006-07-21
Abstract: A method and apparatus are disclosed for providing a DMA process. Accordingly, a DMA process is initiated for moving data from contiguous first locations to contiguous second locations and to a third location or third locations. Within the DMA process the data from each of the contiguous first locations is retrieved and stored in a corresponding one of the contiguous second locations and in the third location or corresponding one of the third locations. The DMA  process is performed absent retrieving the same data a second other time prior to storing of same within the corresponding one of the contiguous second locations and in the third location or corresponding one of the third locations.
Patent CA-2618845-A1 (CA)
Title: Method for foam injection molding of thermoplastic resin
Inventor: OKAMOTO AKIO
IPC: B29C45/00
Filed: 2006-08-23
Abstract: A method for foam injection molding of a thermoplastic resin, the method comprising the steps of: (1) injecting a thermoplastic resin containing a foaming agent from an injection apparatus (30) to fill a mold cavity (10a) with the resin; (2) immediately after the injection/filling of the resin into the mold cavity (10a), releasing the clamp force of a mold (10) to release the pressure of the resin in the mold cavity (10a); (3) maintaining the pressure-released state in the mold cavity (10a) for a predetermined period of time;  (4) expanding the mold cavity (10a) to cause the foaming of the resin; and (5) cooling and maintaining the resin while opening up the mold cavity (10a).
Patent CA-2624839-A1 (CA)
Title: Wetness indicating composition
Inventor: AHMED SHARF U
IPC: A61L15/56
Filed: 2006-10-05
Abstract: A wetness indicating composition is disclosed that changes color in response to a change in pH. The composition comprises a water-insoluble, thermoplastic polymer composition, a superabsorbent polymer, a wetness indicator, and surfactant. The wetness indicating composition is useful in disposable absorbent articles, e.g., disposable diapers, feminine napkins, medical dressings and beddings for humans and animals.
Patent CA-2625431-A1 (CA)
Inventor: GASIK MICHAEL
IPC: F28D20/02
Filed: 2006-10-10
Abstract: The invention relates to a phase change material (PCM) heat exchanger device comprising heat exchanger cells (1a, 1b) operating on the regenerative countercurrent principle, phase change material (PCM) accumulators (2, 3) provided in the heat exchanger cells and a vortex tube (6, 7, 8). When the directions of the air, gas and liquid flows are cyclically reversed in the apparatus, energy is recovered into the heat exchanger cell and the PCM  accumulator, and during the subsequent cycle, the energy is released from the heat exchanger cell and PCM accumulator. While one heat exchanger cell and PCM  accumulator is being charged, the other heat exchanger cell and PCM  accumulator are simultaneously discharged. The cool/hot flow from the vortex tube is used to enhance/create needed temperature differences. The invention is applicable to buildings, vehicles, climate control rooms, single or multiple devices such as computers, and in various processes, such as, but not limited to, cryogenic methods, and in space technology and supercritical carbon dioxide applications.
Patent CA-2633088-A1 (CA)
Title: Fold flat seat assembly
Inventor: HOMIER ROBERT I
IPC: B60N2/30
Filed: 2007-01-05
Abstract: A seat assembly includes a seat cushion and seat back for supporting an occupant above a floor in a motor vehicle. The seat back is operatively mounted for pivotal movement relative to the seat cushion between an upright seating position and a rearwardly folded bed flat position. A guide link slidably engages the seat cushion for guiding and supporting the seat cushion between a seating position and a raised position. A drive link couples the seat back to the seat cushion for automatically moving the seat cushion between the seating and raised positions, wherein the seat cushion is aligned horizontally level with the seat back, in response to pivoting the seat back between the upright seating position and the rearwardly folded bed flat position.
Patent CA-2633874-A1 (CA)
Inventor: ENNIS MICHAEL G
IPC: H01H33/44
Filed: 2008-06-05
Abstract: A fault interrupter and a method of operating a fault interrupter to reduce arcing time during fault interruption. Fault interrupter operation is delayed following detecting a peak current such that its operation occurs at a point of the current wave resulting in reduced arcing during fault isolation.
Patent CA-2636757-A1 (CA)
Title: Aminocyclohexanes as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
Inventor: COX JASON
IPC: A61K31/035
Filed: 2007-01-19
Abstract: The present invention is directed to novel substituted aminocyclohexanes of structural formula (I) which are inhibitors of the dipeptidyl peptidase-IV  enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
Patent CA-2639807-A1 (CA)
Inventor: VU AN BINH
IPC: A61B19/00
Filed: 2008-09-23
Abstract: Apparatus that allows at least one feature of a patient's face to be observed while the patient is in a prone position includes a facial cushion, a video camera and a monitor. The facial cushion provides cranial support for a patient in a prone position during a medical procedure. The cushion has a frontal aperture that is dimensioned so that the facial feature of a patient wearing the facial cushion and in a prone position are visible through the at least one aperture. The video camera has a lens disposed for providing a sequence of video signals representing sequential images of the facial features that are visible through the frontal aperture. The monitor is coupled to the video camera for enabling the images of the at least one facial feature to be monitored. The images are monitored by a video monitor and/or a computer.
Patent CA-2643936-A1 (CA)
Inventor: BILLIANI JOHANN
IPC: C09D7/47
Filed: 2007-03-04
Abstract: A water-reducible mixture of (meth)acrylic copolymers having a hydroxyl number of from 40 mg/g to 250 mg/g, an acid number of from 15 mg/g to 80 mg/g, a weight average molar mass Mw from 9 kg/mol to 40 kg/mol and a glass transition temperature Tg from -40 °C to 80 °C, based on polymerised monomers comprising at least one alkyl ester A of an olefinically unsaturated carboxylic acid having from 1 to 8 carbon atoms in the alkyl group, at least one hydroxy functional alkyl ester B of an olefinically unsaturated carboxylic acid, at least one aliphatic compound C that has both hydroxy and carboxyl functionalities, or which is a lactone or a cyclic lactone, at least one vinyl monomer D which does not comprise a moiety derived from an olefinically unsaturated carboxylic acid, at least one olefinically unsaturated carboxylic acid E, a process for its preparation, and a method of use thereof in the preparation of paints.
Patent CA-2644488-A1 (CA)
Inventor: KONISHI YASUO
IPC: A61P27/12
Filed: 2007-03-23
Abstract: The invention disclosed relates to the use of anti-glycation agents, such as (S)-isoproterenol, and its prodrug, (S)-isoproterenol dipivalate hydrochloride on the initiation of diabetic cataracts. (S)-Isoproterenol is a strong anti-glycation agent with an in vitro IC50 value of 16.8 ± 0.8 µM. (S)-isoproterenol dipivalate hydrochloride was prepared in eye drop form at 0.1% concentration and was applied to diabetic rats twice a day up to 30 weeks. No cataract was observed in non-diabetic rats with or without treatment of the prodrug. In diabetic rats without treatment of the prodrug (group III), 88% of eyes got cataract at 8.6 ± 1.5 weeks. In diabetic rats with treatment of the prodrug, only 53% of the eyes initiated cataract at 8.6 ± 1.2 weeks, and the remaining 26% of the eyes prolonged the initiation to 17.1 ± 3.1 weeks. Furthermore, no cataract was observed in 21% of the eyes even at 30 weeks.
Patent CA-2649438-A1 (CA)
Inventor: VANGSNESS TODD S
IPC: A61M39/04
Filed: 2007-04-11
Abstract: Published without an Abstract
Patent CA-2650353-A1 (CA)
Inventor: KOEHLER DON
IPC: F16N29/04
Filed: 2009-01-19
Abstract: A method is provided for invoking condition monitoring and predicting parametric equipment and lube condition among a plurality of machines; relying on individual or multiple machine and or lube combinations;  comprising establishing a based routine accepting information from multiple sources to simultaneously calculate and compare measured and projected conditions relative to parameters selected to be critical; including multiple condition monitoring techniques like: lube analysis, vibration analysis, thermography, ultrasound and equipment lube monitoring techniques whereas parameters monitored are variables and a specific parametric value represents condition or a group of variables together represents a condition; said variables are not to be confused with attribute data indicating pass/fail without identifying a specific parametric value. The process outputs the specific parameter and days to exceed specified condemning limit for each combination of equipment and lube selected.
Patent CA-2655455-A1 (CA)
Title: Virtual iptv-vod system with remote satellite reception of satellite delivered vod content and method of providing same
Inventor: RUHNKE WILLIAM
IPC: H04H20/40
Filed: 2009-02-25
Abstract: A virtual system and method is provided for delivery of Video-On-Demand content.  The system comprises one or more communications satellites, i.e., domestic and/or international, positioned and adapted for receiving and relaying packet data communications encapsulating a selected video file. A satellite receiver at a first location or remote node acquires and collects the packet data from the one or more satellites and a buffer computer also at the first location, and in proximity to the receiver, re-compiles the packet data into its original video file from beginning to completion. A Video-On-Demand server is positioned at a second location or main node, remote from the first location, for distributing the video file to one or more Internet Protocol Television subscribers over an interactive communications network. The buffer computer at the remote node is linked seamlessly to the Video-On-Demand server at the main node via an Internet-based Virtual Private Network.
Patent CA-2656456-A1 (CA)
Title: Combination of adapalene and benzoyl peroxide for treating acne lesions
Inventor: LOESCHE CHRISTIAN
IPC: A61K31/192
Filed: 2007-07-12
Abstract: The invention relates to the use of adapalene or a pharmaceutically acceptable salt thereof for the manufacture of a pharmaceutical composition for reducing the number of acne lesions, via daily topical application, in combination or in association with benzoyl peroxide (BPO). The recommended treatment may take the form of a pharmaceutical composition combining adapalene and BPO or a concomitant application of two pharmaceutical compositions, one comprising adapalene and the other comprising BPO.
Patent CA-2657989-A1 (CA)
Title: Adjuvant-sparing multi-dose influenza vaccination regimen
Inventor: DEL GIUDICE GIUSEPPE
IPC: A61K39/145
Filed: 2007-06-15
Abstract: An influenza vaccine is administered by a multi-dose regimen, in which (i) a first dose is administered with an adjuvant and (ii) a later dose is administered either without an adjuvant or with a different adjuvant. Thus the invention provides the benefits of a two-dose regimen without also doubling the supply need for a given adjuvant.
Patent CA-2658728-A1 (CA)
Title: Nouveaux materiaux d'electrode presentant une conductivite de surface elevee
Inventor: RAVET NATHALIE
IPC: H01M4/139
Filed: 2000-04-28
Abstract: La présente invention concerne La présente invention concerne les matériau x d'électrode capables de réaction rédox par échange d'ions alcalins et d'électrons avec un électrolyte. Les applications sont dans le domaine des générateurs électrochimiques (batteries) primaires ou secondaires, les supercapacités et les systèmes de modulation de la lumière de type supercapacité.
Patent CA-2659769-A1 (CA)
Inventor: ABE NORIYUKI
IPC: H02P6/08
Filed: 2007-08-09
Abstract: Provided is a hybrid vehicle capable of improving durability and efficiency of an electric motor which is mechanically connected to an engine, thereby improving the commercial value. In the hybrid vehicle (1), an electric motor (10) includes a rotor (14) having a plurality of permanent magnets (14c) and a rotor (15) having a plurality of cores (15b, 15c). The rotor (14) is connected to the front wheels (4) and the rotor (15) is connected to an engine (3). When the magnetic pole of the rotary magnetic field of an armature (16b) is at an opposed position against the magnetic pole of the permanent magnet (14c) and if one of the magnetic poles of the rotary magnetic field and one of the magnetic poles of the permanent magnet(14c) have different polarities, the other of the magnetic poles of the rotary magnetic field and the other of the magnetic poles of the permanent magnet (14c) have identical polarity and if one of the cores (15b, 15c) is positioned between the magnetic poles of the rotary magnetic field and the magnetic poles of the permanent magnet (14c), the other is positioned between magnetic poles of two adjacent sets of rotary magnetic fields and magnetic poles of the permanent magnet (14c).
Patent CA-2661845-A1 (CA)
Inventor: SATO NATSUKI
IPC: A43B13/42
Filed: 2007-06-29
Abstract: Feeling of ride is enhanced at the time of traveling and stability of the foot part of a sole assembly is enhanced. In the foot part (M) of the sole assembly (1) of shoes, an upper plate (3) made of a hard elastic member and arranged above, a lower plate (4) made of a hard elastic member, arranged below the upper plate (3) and having a curved shape convex downward to form an air gap (S) between the upper plate (3) and the lower plate (4), a foot part out sole (6) provided on the bottom surface (4a) of the lower plate (4), having a grounding surface (6a) and separated in front and back directions from the out soles (5, 7) on the heel (H) side and the forefoot (F) side of the sole assembly (1), and coupling portions (8) provided on the front end side and the rear end side of foot part (M) and coupling the upper plate (3) with the lower plate (4) in the vertical direction are provided.
Patent CA-2667645-A1 (CA)
Title: Feuille presentant un effet tactile et un effet interferentiel et document de securite la comportant
Inventor: CHARIGNON SEBASTIEN
IPC: D21H21/44
Filed: 2007-10-31
Abstract: L'invention concerne une feuille (1) comportant un support (2) et un moye n de sécurisation (3) comprenant au moins une zone présentant un effet inter férentiel (4), caractérisée en ce que ledit moyen de sécurisation (3) compor te en outre au moins un 10 élément de reconnaissance tactile (5) situé dans la même région que ladite zone présentant un effet interférentiel (4). L'inv ention concerne également un document de sécurité et un article à authentifi er comprenant ladite feuille (1).