baber/WOPTO huggingface dataset:
Patent AU-2020395612-A1 (AU)
Title: Methods of activating cytotoxic leukocytes using PTP1B and PTPN2 inhibitors
Inventor: TIGANIS TONY
IPC: A61K31/662
Filed: 2020-12-04
Abstract: The present invention generally relates to methods of activating cells via the inhibition of PTP1B and PTPN2 for use in therapy. For example, the invention relates to preparing cells ex vivo for use in immunotherapy, particularly cancer immunotherapy. More specifically, the invention relates to methods for the preparation of leukocytes, particularly T cells, exhibiting cytotoxic properties for use in adoptive cell transfer. The invention also relates to cells and compositions including them for cancer immunotherapy. The invention also relates to methods of immunotherapy, particularly cancer immunotherapy.
Patent AU-2020407110-A1 (AU)
Title: Selective white blood cell lysis for immunoassay systems
Inventor: SAMBURSKY ROBERT P
IPC: C12Q1/04
Filed: 2020-12-18
Abstract: A test strip with selective white blood cell (WBC) lysis for release of WBC contents and the capture and holding of red blood cells (RBC), allowing for fast clearance and result interpretation and more accurate results at early time points due to the lack of red color interference caused by background red heme color of lysing of RBCs. The removal of the red color interference enhances both visual and digital interpretation of test strips, such as test strips of an immunoassay test. The test strip enhances the detection of both intracellular proteins of WBCs and extracellular proteins of RBCs simultaneously such as MxA and CRP, MxA and PCT, MxA and HNL, and MxA and IL-6, MxA and myeloid cells (sTREM-1), MxA and angiopoietin 2, MxA and vascular endothelial growth factor (VEGF) or its soluble vascular endothelial growth factor receptor-1 (sVEGFR1), MxA and heparin binding protein (HBP) or other combinations.
Patent AU-2020416625-A1 (AU)
Title: Method and device for the automated arrangement of tunnel lining segments
Inventor: SENG FREDERIC
IPC: E21D11/40
Filed: 2020-12-31
Abstract: The invention relates to a device for the automated installation of at least one tunnel lining segment of a tunnel lining ring, said device being couplable to a tunnelling machine, • having a manipulator with at least one tool for receiving, holding and placing the at least one tunnel lining segment, and with at least one actuator for moving the at least one tool, the at least one tool being movable by means of the at least one actuator in the radial, tangential and/or axial direction in relation to the machine axis of the tunnelling machine in the space of the tunnel section created by the tunnelling machine, • having at least one tool position sensor, which is provided on the manipulator and/or tool, for sensing the respective actual position and actual location of the tool in the space of the tunnel section, • having at least one tunnel lining segment sensor, which is provided on the manipulator and/or tool, with which an actual position and/or actual location of at least one section of at least one already arranged tunnel lining segment can be sensed, and/or with which an actual position and/or actual location of the tunnel lining segment to be placed can be sensed, • having a controller, which accesses installation data of the tunnel lining segments and which accesses the measurement data of the at least one tool position sensor and the at least one tunnel lining segment sensor, and with which the at least one actuator and the at least one tool can be controlled on the basis of the installation data and measurement data in order to move the tool from the receiving position to the target placing position of the respective tunnel lining segment and to orient same in the actual placing position and to arrange same against the at least one already placed tunnel lining segment of the tunnel lining ring, wherein at least two tunnel lining segment sensors are provided, and wherein the tunnel lining segment sensor is a time-of-flight camera.
Patent AU-2020430267-A1 (AU)
Title: Main beam for fan blade and manufacturing method therefor
Inventor: LIANG YUAN
IPC: F03D1/06
Filed: 2020-02-18
Abstract: A main beam (100) for a fan blade, comprising: one or more carbon fiber pultruded bodies (101), wherein each carbon fiber pultruded body (101) comprises one or more carbon fiber pultruded plates (101a), which are stacked in the thickness direction and formed by solidifying a first pouring material, wherein a glass fiber pouring material is arranged between every two carbon fiber pultruded plates (101a); one or more inserts (102) arranged adjacent to the carbon fiber pultruded bodies (101) in a direction perpendicular to the thickness direction of the main beam (100); one or more covering layers (103) that cover the carbon fiber pultruded bodies (101) and/or the inserts (102) on both sides in the thickness direction of the main beam (100); and a second pouring material (101b) that infiltrates the carbon fiber pultruded bodies (101), the inserts (102) and the covering layers (103). By means of the main beam, various properties of the blade such as rigidity can be adjusted while the consumption of carbon fibers are reduced, and the adherence of the main beam to a curved mold is improved and the defects of bubbles and wrinkles etc. are reduced, thus increasing the required rigidity of the main beam and prolonging the service life of the main beam. Further disclosed are a method for manufacturing the main beam and a wind driven generator comprising the main beam.
Patent AU-2020467852-A1 (AU)
Title: Method and system of simulations for personalized brain treatments
Inventor: YOUSEFIROSHAN HAMED
IPC: A61F2/00
Filed: 2020-09-09
Abstract: Systems and methods provide a novel approach for decision making and planning of neurovascular treatments and high-fidelity outcome prediction of every potential treatment. The invention, particularly, uses the clinical data of the patients for a personalized treatment planning and simulation in which a personalized anatomical model of the patient is constructed virtually, a neurovascular device implantation may be done virtually and by simulation, a computational fluid dynamics (CFD) simulation is done, and finally by using some post-processing parameters, indices and principles a prediction is made regarding the outcome of each potential treatment. The system comprises one or more processors to receive patient-specific data regarding a geometry of an anatomical structure of the patient and to simulate deployments of different neurovascular devices and their corresponding hemodynamics in anatomical structure models and to generate a report for each potential deploymen.
Patent AU-2021200559-A1 (AU)
Title: Reduced latency server-mediated audio-video communication
Inventor: CARAS JONATHAN
IPC: H04M3/537
Filed: 2021-01-29
Abstract: Video communications between multiple computer systems configured to transmit and 
receive video content. A client transmitter is enabled to transmit a video message for display 
on the client recipient. The client transmitter is configured to transmit or record the video 
message to the video server. The video message is archived by the video server. When the 
client recipient is unavailable during the beginning of the transmission of the video message 
and when the client recipient is available later during the transmission of the video message, 
the client recipient is enabled to display the video message from the beginning of the video 
message while the transmission of the video message is still ongoing.
Patent AU-2021203444-A1 (AU)
Title: Cleaner
Inventor: NAM BOHYUN
IPC: A47L9/28
Filed: 2021-05-26
Abstract: Some embodiments relate to a cleaner. The cleaner may comprise: a suction inlet 
configured to guide air into the cleaner; a suction motor configured to drive a rotation 
of a rotary impeller via an impeller shaft to generate a suction force that suctions air 
into the cleaner through the suction inlet; and a dust separation unit. The dust 
separation unit may comprise: a first cyclone unit configured to separate dust from 
air that is suctioned into the cleaner through the suction inlet; and a second cyclone 
unit disposed at a lower side of the suction motor and configured to separate dust 
from air that is received from the first cyclone unit. The cleaner further comprises a 
printed circuit board (PCB) for controlling an operation of the suction motor, the PCB 
being disposed between the suction motor and the second cyclone unit. The rotary 
impeller, the suction motor, the PCB, and the second cyclone unit may be disposed 
to overlap each other in an extending direction of the impeller shaft.
Patent AU-2021203970-A1 (AU)
Title: Equipment architecture for high definition data
Inventor: KILWORTH TIMOTHY J
IPC: G05B19/042
Filed: 2021-06-15
Abstract: Disclosed is a data processing system, comprising: a plurality of sensors sensing 
variables on a first mobile machine; and a processing system on the first mobile machine 
that receives sensor information from the plurality of sensors and generates low resolution 
data indicative of the sensor information and that generates high resolution data, that is 
higher resolution than the low resolution data, and transmits the low resolution data and the 
high resolution data to another processing system over a transmission link.
Patent AU-2021204767-A1 (AU)
Title: Methods for treating patients with heterozygous familial hypercholesterolemia (heFH)
Inventor: BACCARA-DINET MARIE
IPC: C07K16/40
Filed: 2021-07-08
Abstract: The present invention provides methods for treating hypercholesterolemia. The 
methods of the present invention comprise administering to patients with heterozygous 
familial hypercholesterolemia a pharmaceutical composition comprising a PCSK9 inhibitor.  
In certain embodiments, the PCSK9 inhibitor is an anti-PCSK9 antibody such as the 
exemplary antibody referred to herein as mAb316P. The methods of the present invention 
are useful for treating patients with heterozygous familial hypercholesterolemia who are not 
adequately controlled by maximum tolerated dose statin therapy with or without other lipid 
lowering therapy.  
17784553_1 (GHMatters) P42586AU01
Patent AU-2021218176-A1 (AU)
Title: Tag layout for industrial vehicle operation
Inventor: WALTON DANIEL D
IPC: G05D1/02
Filed: 2021-08-20
Abstract: A system comprising a tag layout and an industrial vehicle, wherein: the industrial vehicle 
comprises storage and retrieval hardware, a tag reader, a reader module, and a vehicle 
controller; the storage and retrieval hardware is configured to store and retrieve items from 
selected storage elements positioned along an aisle path; the tag reader and the reader module 
cooperate to identify individual tags along the aisle path; the tag reader comprises two read 
antennas positioned on opposite sides of a longitudinal travel axis of the industrial vehicle; 
the read antennas define respective read ranges and generate respective tag read signals when 
tags enter the respective read ranges of the read antennas; the tag layout comprises individual 
tags along only one side of the aisle path such that one of the read antennas will be positioned 
over the individual tags of the tag layout regardless of the direction of travel of the industrial 
vehicle; the tag reader and the reader module further cooperate to generate a vehicle direction 
signal when the individual tags are identified primarily with reference to tag read signals 
from only one of the two read antennas; the vehicle controller controls vehicle functionality 
partially as a function of the vehicle direction signal.
Patent AU-2021225247-A1 (AU)
Title: Variant adeno-associated viruses and methods of using
Inventor: DUDMAN JOSHUA
IPC: A61K48/00
Filed: 2021-09-03
Abstract: The present disclosure provides AAV variants that exhibit a preference for retrograde 
movement in neurons and methods of using such variants.
Patent AU-2021236513-A1 (AU)
Title: Anti-GD2 antibody for the treatment of neuroblastoma
Inventor: LEUSEN JEANNETTE HENRICA WILHELMINA
IPC: C07K16/30
Filed: 2021-09-23
Abstract: The invention relates to anti-ganglioside GD2 antibodies that comprise an 
antibody variable domain and antibody constant domains, wherein the variable 
domain comprises a heavy and light chain variable region comprising respectively 
at least the CDR3 of the heavy chain variable region of antibody chl4.18 and at 
least the CDR3 of the light chain variable region of antibody chl4.18; and an IgA 
hinge and CH2 domain and to methods of treatment of subjects with a GD2 positive 
tumor, preferably neuroblastoma with these antibodies.
Patent AU-2021240175-A1 (AU)
Title: Model learning apparatus, control apparatus, model learning method and computer program
Inventor: MORIYASU RYUTA
IPC: G05B13/04
Filed: 2021-09-29
Abstract: A model learning apparatus includes: a model storage portion 
configured to store a model used to learn a nonlinear equation of state for 
predicting the output variable y by using the input variable v; and a 
learning portion configured to learn the equation of state by using the model 
and an input-output data set including multiple sets of input variable data 
and output variable data with respect to the model, wherein the model is an 
equation of state including a bijective mapping y that uses the input 
variable v as an input thereof and a bijective mapping < that uses the 
output variable y as an input thereof.
1 
FIG.1 0oo 
p110 p120 
CPU STORAGE MODULE 
CONTROLLER 1111 [ MODEL STORAGE PORTION 121 
DATA SET STORAGE PORTION 122 
LEARNING MODULE ~112 
<-->ROM/RAM ~-130 
COMMUNICATION MODULE -140 
INPUT-OUTPUT MODULE 150
Patent AU-2021259042-A1 (AU)
Title: Robot cleaner and method of controlling robot cleaner
Inventor: SHIN YONGGIL
IPC: A47L11/40
Filed: 2021-04-23
Abstract: The present invention relates to a method of controlling a robot cleaner, which comprises a pair of rotating plates having mops facing the floor surface coupled to lower sides thereof, and is configured to travel by rotating the pair of rotating plates, the method comprising: a region setting step in which a cleaning region on the floor surface is set; and a travel step in which the robot cleaner travels in the cleaning region, wherein in the region setting step, the cleaning region is set by subdividing same into a plurality of sub-regions. Since the plurality of sub-regions are at least partially overlapped with one another, there is an advantage in that while the entire cleaning region is being cleaned, a certain region may be repeatedly cleaned.
Patent AU-2021268278-A1 (AU)
Title: Systems and methods for distributed data analytics
Inventor: OLSEN LARS
IPC: G06V10/56
Filed: 2021-05-10
Abstract: The invention provides systems and method for generating device-specific artificial neural network(ANN) models for distribution across user devices (105). Sample datasets (140) are collected from devices in a particular environment or use case and include predictions by device-specific ANN models executing the user devices. The received datasets are used with existing datasets and stored ANN models to generate updated device-specific ANN models from each of the stored instances of the device ANN models based on the training data.
Patent AU-2021278069-A1 (AU)
Title: Engineered immune cell and use thereof
Inventor: XING YUN
IPC: A61K35/17
Filed: 2021-05-24
Abstract: An engineered immune cell, which expresses (i) a cell surface molecule that specifically recognizes a ligand, (ii) an exogenous interleukin, and (iii) an exogenous Flt3L, XCL2, and/or XCL1; the engineered immune cell can be used for treating cancer, infection, or autoimmune diseases; and compared with a traditional engineered immune cell, the engineered immune cell has significantly improved tumor killing activity.
Patent AU-2021305373-A1 (AU)
Title: Method of preparing casein hydrolysate
Inventor: RAY COLIN A
IPC: A23L33/19
Filed: 2021-07-06
Abstract: The present invention relates to a method of preparing a casein hydrolysate by hydrolysis of casein with endogenous plasmin, and the casein hydrolysate obtainable by the method. In particular, the present invention relates to a method of preparing a casein hydrolysate without adding any exogenous enzymes such that an organic casein hydrolysate is obtained.
Patent AU-2021309717-A1 (AU)
Title: Method for synthesising 2-bromoglutaric acid diesters
Inventor: PARATIAN JEAN-MICHEL
IPC: C07C67/08
Filed: 2021-07-16
Abstract: The present invention relates to a method for preparing a 2-bromoglutaric acid diester of formula (I), comprising forming a 2-hydroxyglutaric acid diester of formula (II) by reacting butyrolactone acid of formula (BA) with alcohol of formula ROH, in the presence of an acid such as sulphuric acid; and brominating the 2-hydroxyglutaric acid diester of formula (II) by bubbling gaseous hydrobromic acid. The present invention further comprises a 2-bromoglutaric acid diester of formula (I) having a degree of purity determined by HPLC analysis that is greater than or equal to 90%.
Patent AU-2021335406-A1 (AU)
Title: Methods and cells for production of volatile compounds
Inventor: POGREBNYAKOV IVAN
IPC: C12P7/28
Filed: 2021-09-01
Abstract: The present invention relates to thermophilic cells and methods for the microbial production of volatile compounds, including acetone, butanone and isopropanol. Also provided are nucleic acid constructs, vectors and host cells useful in such methods.
Patent AU-2021336896-A1 (AU)
Title: Orbital confinement fusion device
Inventor: LANGTRY ROBIN
IPC: H05H1/02
Filed: 2021-09-02
Abstract: Systems, devices, and methods for generating an orbital confinement fusion reaction are described. An orbital confinement fusion device can include a cathodic inner electrode defining a longitudinal axis of the device. The inner electrode can include an emitter material. The orbital confinement fusion device can include an anodic outer electrode, concentric with the longitudinal axis and defining a chamber between the inner electrode and the outer electrode. The orbital confinement fusion device can also include a plurality of magnetic field generators disposed in a coaxial arrangement relative to the longitudinal axis. The plurality of magnetic field generators can be configured to form a magnetic field parallel to the longitudinal axis in the chamber.
Patent AU-2021344972-A1 (AU)
Title: Detection of circulating tumor cells using tumor-targeted nir agents
Inventor: KULARATNE SUMITH A
IPC: C07K16/30
Filed: 2021-09-16
Abstract: The present disclosure relates to methods and compositions for detecting circulating tumor cells (CTCs) using a compound comprising a targeting moiety and a fluorescence imaging agent.
Patent AU-2021345273-A1 (AU)
Title: Systems and methods for remote, virtual, in-home, and hybrid virtual-in-home veterinary medicine
Inventor: HERZFELDER BRUCE
IPC: G06Q10/00
Filed: 2021-09-17
Abstract: The present disclosure provides systems and methods for remote, virtual, in-home, or hybrid virtual-in-home veterinary medicine.
Patent AU-2021380964-A1 (AU)
Title: Mass spectrometry system and method for providing an indication of integrity of a biological sample
Inventor: GEYER PHILIPP EMANUEL
IPC: G16B40/10
Filed: 2021-11-19
Abstract: A mass spectrometry system comprises a mass spectrometry apparatus configured to provide mass spectrometry data of a biological sample; and a computer system configured to process the mass spectrometry data to determine a characteristic of the biological sample as integrity data of the biological sample; and output an indication of the similarity to a predetermined sample characteristic as integrity data of the biological sample. A computerized method provides an indication of integrity of a biological sample from mass spectrometry data, the computerized method comprising: processing mass spectrometry data of a biological sample to determine a sample characteristic of the biological sample; and outputting an indication of the similarity to a predetermined sample characteristic as integrity data of the biological sample.
Patent WO-2023064986-A1 (WO)
Title: A device and system for the secure storage of data in a distributed manner
Inventor: ELBAUM HECTOR
IPC: G06F21/72
Filed: 2022-10-19
Abstract: This specification describes a network of storage devices for encrypting and storing data. A first storage device of the network comprises: a mechanism or system for authenticating a user via user interaction directly with the first storage device, a mechanism for connecting over a local connection with one or more user devices, and computer-readable memory for storing electronic data on the first storage device. The first storage device is configured to receive, over the local connection and from a first of the one or more user devices, first data for storage at the first storage device, to encrypt the first data and store the encrypted first data locally in the computer-readable memory of the first storage device; to split the encrypted first data into multiple portions; to apply a cryptographic signature to each of plural groups of one or more of the portions, the cryptographic signature enabling the first storage device to be identified and authenticated by other storage devices of a network of storage devices, to send each of the cryptographically signed groups to a respective other storage device of the network of storage devices, and to create a first record which associates the first data with the other storage devices of the network to which the cryptographically signed groups of were sent. The first storage device is further configured to, responsive to a request to access the first data, the request to access the first data resulting from a user request to access the first data provided to a user device and received at the first storage device via a local connection with the user device, retrieve the encrypted first data from the computer-readable memory, deciypt the encrypted first data, and send, over the local connection with the user device to which the user request to access the first data was provided, the decrypted first data. The first storage device is further is configured to: receive a request for transmission of previously- received, cryptographically signed second data, authenticate the request for the transmission of the previously-received, cryptographically signed second data as having originated from another storage device of the network of storage devices, and having authenticated the request for the transmission of the previously-received, cryptographically signed second data as having originated from another storage device of the network of storage devices, send the previously-received, cryptographically signed second data to the other storage device of the network of storage devices.
Patent AU-2022200697-A1 (AU)
Title: System and method for terrain based control of self-propelled work vehicles
Inventor: OGLESBY MADELINE T
IPC: G05D13/58
Filed: 2022-02-03
Abstract: OF THE DISCLOSURE 
A terrain-based travel assist system and method are provided for stability control in 
a self-propelled work vehicle such as an excavator comprising ground engaging units and at 
least one work implement configured for controllably working terrain. Upon selecting or 
determining a travel mode for the work vehicle, the respective predetermined target positions 
and/or operations of the at least one work implement are retrieved from data storage, 
corresponding to the determined travel mode. Feedback signals are received from sensors 
corresponding to respective current positions and/or operations of the at least one implement, 
and in some embodiments to a vehicle speed. Control signals are generated for automatically 
controlling the at least one work implement to the respective predetermined target positions 
and/or through the respective operations, responsive to the determined travel mode and the 
received feedback signals.  
25
2/5 
104 Sensor 
System 
112 
114-- 5 5 
118 
Steering Implement Speed 
Control Control Control 
126 128 130 
FIG. 2