Patent RU-2604938-C2 (RU)
Inventor: TUGOLUKOV ALEKSANDR VLADIMIROVICH
IPC: A61B3/113
Filed: 2015-03-06
Granted: 2016-12-20
Abstract: FIELD: medicine. 
     SUBSTANCE: group of inventions relates to medicine. Contactless pupillometr for screening diagnosis of functional state of the body comprises a body, holder, radiator, receiver, temperature sensor, chamber, housing, position indicator, two infrared (IR) light-emitting diode, red light-emitting diode, source of white light, light sensors and computer with software. Body is made of complex shape, which can be divided into two surfaces, forming shield and enclosing boards. Front end side of shield of body has concave shape, that is, in plan is represented by arc in the centre of which there is a temperature sensor, and at the edges are symmetrically arranged radiator and receiver respectively, to that light flux of radiator falls directly on the receiver. Radiator is represented by photo electrosensor, generating light flux. Receiver is represented by photo electrosensor, receiving light flux from the radiator. Temperature sensor is represented by infrared thermometer providing non-contact measurement of temperature. In the inner part of the protecting casing at the center there is a chamber in the casing and position indicator, and on side opposite from the chamber is mounted two infrared light-emitting diode. Casing is made of material capable of uniform distribution of light. Position indicator is located above the chamber and is made of material, surface of the profiled sides of which has a reflecting capacity, with a degree of definition sufficient for reflecting eye contours. Two IR light-emitting diode operate in the range of infrared light, and perform function of constant continuous illumination of right and left eye, respectively. In the upper part of the body there is a light sensor. On rear wall of casing behind the chamber are located red light-emitting diode and a source of white light. When covering the light flux from the emitter to the receiver is activated red light-emitting diode. Enclosing boards of the housing together with a shield, as well as with two IR light-emitting diodes and illumination sensor are created and measured the condition of background illumination. Contactless method of screening diagnosis of functional state of an organism comprises the step of pre-research, stage of analysis and a enclosing step. At the stage of pre-research are carried out registration of identification code of a person, under which information is stored in the future; positioning of the person being tested and creation of background illumination, for this purpose, the person being tested, at continuous operation of two IR light-emitting diodes, not touching surfaces of the case and seeing reflection of the eye on the indicator position, bringing its head to the front end side of the shield body until it overlaps the beam path from the emitter to receiver, thus activating operation of red light-emitting diode. At the stage of analysis, at continuous operation of red light-emitting diode and brighting-up eyes IR light-emitting diodes, is carryed out contactless continuous simultaneous measurement of background lighting readings, temperature of the human body and the pupil reaction of eye in three series changed modes: adaptation, load and reduction. Mode of adaptation lasts from the moment of switching on red light-emitting diode to the moment of switching on white light source; load mode is characterised by the operation of turned-on white light source; recovery mode lasts from the moment of turn off white light source to the moment of blinking red light-emitting diode. At the stage of conclusion is carried out entering in the database of PC under the patient's identification code of measurement. Processing and analysis of measurements. At the same time for measuring the pupil reaction is carried out processing of each image frame in digital form at pixels and by statistical processing of plotting the change of area of the pupil in time, depending on illumination. Then calculation is performed, at least, the following parameters: latent pupil reaction time on white light source (Tlat1), latent pupil reaction time at disconnection of white light source (Tlat2), angle of the pupil reaction on activation of white light source (F1), angle of the pupil reaction on deactivation of white light source (F2), coefficient of reaction (AmplRatio), average area of the pupil before reaction (Average). Then, at least on five researches is carried out formation of individual norms of the testing patient, in which for each value Tlat1, Tlat2, F1, F2, AmplRatio, Average minimum and maximum values are defined with allowance in 10%. During repeated examination is carried out automatic comparison of design parameters of pupillary response of the investigated with the same individual normal values with the issuance epicrisis of functional status of an organism. 
     EFFECT: using the given group of inventions allows increase accuracy of measurements, as well as reduce the time of examination. 
     11 cl, 9 dwg, 2 ex