baber/WOPTO huggingface dataset:
Patent JP-2018510966-A (JP)
Title: 元素ロジウムを生成する方法
IPC: C22B3/22
Filed: 2016-02-01
Abstract: 元素ロジウムを生成する方法であって、（１）ハロゲン化水素酸で−１から＋２のｐＨ値に調整したジエチレントリアンモニウムヘキサハロゲノロジウム酸塩の水性懸濁液を準備する工程と、（２）ジエチレントリアンモニウムヘキサハロゲノロジウム酸塩の完全な変換のために十分な量の還元剤を、工程（１）で準備した前記懸濁液に添加し、元素ロジウムの形成が完了するまで反応を進行させる工程と、（３）工程（２）において形成した前記元素ロジウムを、工程（２）において形成したハロゲン化水素水性組成物から分離する工程とを含み、ハロゲンが臭素および／または塩素である、方法が開示される。【選択図】なし
Patent JP-2018505828-A (JP)
Title: 手動テーピング器具
IPC: B65H35/07
Filed: 2016-01-18
Abstract: 手動テーピング装置。改良された手動操作式テーピング装置であって、貼着されるテープのリーディング端部を制御するもので、これは、引戻し機構によって行われ、テープが切断された直後、又は制動作用若しくは接着グリップ作用若しくはその両方の直後にテープのリーディング端部が引き戻されるようにし、また、テープのカッティング制御機構及びカッティングナイフの安全保持機構を含む。装置はまた、テープ貼着中、装置を、テープと装置との間を相対移動する方向に確実に移動させるためのガイドを含むことができる。【選択図】 図２ｂ
Patent JP-2017537166-A (JP)
Title: 癌免疫療法におけるアジュバントとしてのブロモドメイン阻害剤
IPC: A61K39/395
Filed: 2015-12-04
Abstract: 本明細書は、抗原提示細胞におけるブロモドメインタンパク質の阻害がより炎症性であり、免疫抑制分子PDL1のより低い発現を示し、寛容性T細胞の応答性を回復する能力を有することを示す。したがって、癌免疫療法を受けている対象にブロモドメイン阻害剤含有組成物を投与することを伴う、対象における癌免疫療法中にT細胞活性化を促進するための方法が開示される。対象にブロモドメイン阻害剤と免疫刺激剤とを共投与することを含む、癌を治療するための方法もまた開示される。【選択図】 なし
Patent JP-2018510509-A (JP)
Title: ピークホールドドライバによって制御されるソレノイドバルブのドロップアウトの確保
IPC: H01F7/18
Filed: 2016-03-17
Abstract: ソレノイドバルブにおいてソレノイドコイルを制御するシステム及び方法は、監視又は漏洩電流がピークホールドドライバで用いられることを可能にするコントローラを提供する。コントローラは、前記ソレノイドコイルの適切なドロップアウトを確保するために、前記ソレノイドコイルが直ぐに再度通電状態にされることを防ぐドロップアウト電圧の検出後に、遅延時間を導入する。遅延時間は、ソレノイドコイルの電流に関してコントローラがアクションを取らない間に待機時間を課し、ソレノイドコイルが非通電状態となり、その通常開位置又は通常閉位置にバルブを戻すことを可能にする。遅延時間のこのような使用は、コントローラが電源オンサイクルを既に終ええた場合に限定されてもよい。ソレノイドコイルを通電状態にするためにコントローラによって必要とされる応答時間が、最小化され、よって、バルブのスタートアップ時間を低減する。【選択図】図１
Patent JP-2018510470-A (JP)
Title: イオン−イオンプラズマ原子層エッチングプロセス及びリアクタ
IPC: H05H1/46
Filed: 2016-01-15
Abstract: オーバーヘッド電子ビーム源を有するリアクタは、原子層エッチングプロセスを実行するためのイオン−イオンプラズマを生成することができる。
Patent JP-2018514176-A (JP)
Title: 充電方法、充電装置、及び端末
IPC: H02J7/04
Filed: 2015-05-19
Abstract: 充電方法、充電装置、及び端末が開示される。当該方法は、充電ケーブルを使用することによって端末の充電ポートへ充電装置が挿入されていることが検出されたときに、充電ポートの第１電圧値を特定する段階と、第２充電電流を設定する段階と、第２充電電流における、充電ポートの第２電圧値を特定する段階と、第１電圧値、第２充電電流、及び第２電圧値に従って充電ケーブルのケーブルインピーダンスを計算する段階と、充電ケーブルのケーブルインピーダンスに従って充電装置の適切な充電電流を調整する段階とを備える。従って、端末は種々の充電装置に適応でき、充電に関するユーザエクスペリエンスが改善する。
Patent JP-2018516159-A (JP)
Title: ホットタック強度を改善するための炭酸カルシウムの分散容易性
IPC: C09D7/80
Filed: 2016-03-23
Abstract: 本発明は、押出コーティング材料の製造方法、この方法により製造された押出コーティング材料、押出コーティング材料を含む物品、および押出コーティング材料のラミネーション方法における使用に関する。
Patent JP-2018517636-A (JP)
Title: コンベヤ用送り込み及び送り出しアッセンブリ
IPC: B65G21/06
Filed: 2016-04-21
Abstract: コンベヤにおいて、送り込みアッセンブリおよび送り出しアッセンブリを使用し、そのそれぞれが、コンベヤフレームに取付けることのできるノーズバーアッセンブリを具えて、コンベヤベルトをリターン方向と搬送方向との間で移行させる。送り出しアッセンブリは更に、駆動スプロケットと、コンベヤベルト上の駆動要素と駆動スプロケットとの係合を確実にするリミッタとを具える。リミッタプレートは、駆動スプロケットに対するリミッタの適切な配置を確実にする。送り込みアッセンブリおよび送り出しアッセンブリは、交換、クリーニングまたはメンテナンスが楽になるように、コンベヤフレームに容易に取付けることができ、かつコンベヤフレームから容易に取外すことができる。 【選択図】図２
Patent JP-2018516067-A (JP)
Title: イヌ血管内皮成長因子へ結合する抗体およびイヌ血管新生関連疾患の処置におけるその使用
IPC: A61K45/00
Filed: 2016-04-06
Abstract: 本明細書に開示されるのは、イヌ血管内皮成長因子を阻害することができる抗体および増殖性疾患などのイヌ血管新生関連障害の処置におけるその使用である。
Patent JP-2018518865-A (JP)
Title: ブロードキャスト送信および受信のための方法およびデバイス
IPC: H04B7/06
Filed: 2015-04-20
Abstract: 互いに関連付けられている、ビーム掃引パターンを使用する、ブロードキャストされるメッセージの送信および受信のための、ネットワークノード（６００；７００）、クライアントデバイス（８００；９００）と、それらのネットワークノードおよびクライアントデバイスでの方法とが開示される。第１のビーム掃引パターンと、第２のビーム掃引パターンとの間の関連付けに関する情報を伴うクライアントデバイスは、ページングメッセージの受信のために監視すべき、とき、および、ところを、パイロットメッセージの受け取りに基づいて決定し得る。このことは、ＵＥに対する電力効率改善を、掃引モードで送信される、ブロードキャストされるメッセージを監視するときにもたらす。【選択図】図４
Patent JP-2018517459-A (JP)
Title: 流体ポンプ用ロータならびにその製造方法および金型
IPC: A61M1/10
Filed: 2016-04-29
Abstract: 圧縮性の流体ポンプ、特に、血管を通じて患者の身体に導入可能な血液ポンプ用のロータであって、１つ以上のインペラ要素１５を備え、展開状態と圧縮状態との間で圧縮および展開可能であり、少なくとも一部が繊維１０、１１、１３、１８、１９強化プラスチック材料で構成され、回転軸線１４周りに回転するように構成され、当該ロータ４２の展開状態において、繊維１０、１１、１３、１８、１９の第１の割合すなわち３０％超、特に、５０％超が、回転軸線に最も近く存在する第１の端部１０ａ、１１ａ、１３ａから回転軸線の遠くに存在する第２の端部１０ｂ、１１ｂ、１３ｂへと実質的に真っ直ぐ延びることを特徴とするロータが開示される。本発明によれば、ロータは、機械的応力を繰り返し受けた場合であっても、その形状を非常によく維持する。
Patent JP-2018515516-A (JP)
Title: 肝硬変に罹患した患者における細菌感染症の処置のための方法及び医薬組成物
IPC: A61K31/4745
Filed: 2016-05-12
Abstract: 本発明は、肝硬変に罹患した患者における細菌感染症の処置のための方法及び医薬組成物に関する。具体的には、本発明は、肝硬変に罹患した患者における細菌感染症を処置する方法であって、患者に治療有効量のＴＬＲ７及び／又はＴＬＲ８アゴニストを投与することを含む方法に関する。
Patent JP-2018516958-A (JP)
Title: 哺乳動物における非ヒスタミン性掻痒の治療方法
IPC: A61P17/14
Filed: 2016-05-19
Abstract: 非ヒスタミン性掻痒の治療を必要とする哺乳動物を治療する方法であって、治療を必要とする哺乳動物に治療上有効な量のＲＳ−ノルケトチフェン、異性体またはその薬学的に許容される塩を投与して、それにより前記哺乳動物が掻くという要求を低減する方法が、本明細書において開示されている。非ヒスタミン作動性タイプの掻痒は選択的ヒスタミンＨ−１、Ｈ−２およびＨ−４受容体阻害剤での治療に耐性である。ある態様において、非ヒスタミン作動性掻痒は、皮膚疾患、神経疾患、または全身性疾患に関連している。
Patent JP-2018511900-A (JP)
Title: 動的に調整可能な購入予約の更新度合−製品消費入力
IPC: G06Q30/06
Filed: 2016-03-18
Abstract: 自動商品購入予約システムに対して、消費者に所有されている商品の量、ならびにその商品に対する後続の交換日を決定するためのメカニズムが記載される。残っている商品の量は、多数の要因から算出される消費率によって決定されて良い。消費率は、クラスタデータまたは基礎商品に関連した傾向を表すデータに基づいて良い。消費者は、商品購入に基づいてクラスタリングされて良いし、その消費者クラスタの共通消費率は、その消費者に適用されて良い。商品の消費率が変化するにつれて、交換日は、消費率の変化を反映するため動的に更新されて良い。【選択図】図７
Patent JP-2019120339-A (JP)
Title: Tripod type equal velocity universal joint
Inventor: ITAGAKI TAKU
IPC: F16D3/205
Filed: 2018-01-09
Abstract: To provide a tripod type equal velocity universal joint in which a vibration at a vehicle caused by a sliding resistance is reduced, it is directly related to improvement in NVH characteristic and further it shows a superior productivity.SOLUTION: An outer peripheral surface of an outer roller of a roller mechanism has an outside surface and an inside surface that cross with a shaft center line of the outer roller and arranged symmetrically in respect to a plane passing through a center point of the outer roller. The outside surface is formed with an outer tapered surface at an outside part. The inside surface is formed with an inner tapered surface inside of it. The outer tapered surface and the inner tapered surface are connected by a radius protruded at a roller guide surface side. A roller guide surface of a truck groove is constituted by an outer taper guide surface corresponding to an outer taper surface of the outer roller, an inner taper guide surface corresponding to an inner taper surface of the outer roller, and a radius guide surface connecting the outer taper guide surface with the inner taper guide surface.SELECTED DRAWING: Figure 1
Patent JP-2019119968-A (JP)
Title: Pair of garment connectors and garment connected by the same
Inventor: IESAKI TAKASHI
IPC: A41D27/00
Filed: 2018-01-09
Abstract: To provide a garment connector and the like, capable of connecting between an outerwear and an innerwear even when the innerwear has a coupling structure by engagement between one and the other hook components and the outerwear has a coupling structure by a linear slide fastener, or vice versa.SOLUTION: A pair of garment connectors are composed of one and the other garment connector 21 and 22 including strips 25 and 26, fastener elements 27a and 28a, and hook components 29 and 30, respectively. The fastener elements 27a and 28a are not only engaged between right and left outer side elements 15a and 16a of an outerwear 1 but also engaged with right and left inner side fastener elements 59a and 64a of another innerwear 52, respectively, and the hook components 29 and 30 are not only connected between right and left inner side hook components 3 and 4 of an innerwear but also connected to right and left outer side hook components 56 and 58 of another outerwear 51, respectively.SELECTED DRAWING: Figure 4
Patent JP-2019121581-A (JP)
Title: Mass spectrometer and mass spectroscopy method
Inventor: Sakuta masahiro
IPC: G01N27/62
Filed: 2018-01-11
Abstract: To provide a mass spectrometer capable of improving detection accuracy of a first substance including a second substance such as an impurity without enlarging the device and capable of shortening a measurement time, and a mass spectroscopy method.SOLUTION: The present invention relates to a mass spectrometer 110 for analyzing a specimen containing a first substance consisting of an organic compound and one or more second substances consisting of an organic compound and overlapping a peak of a mass spectrum with the first substance. The mass spectrometer comprises a peak correction part 217 by which, based on a nonlinear strength relationship F between a peak A that is not overlapped with the peak of the mass spectrum of the first substance and a peak B that is overlapped with the peak of the first substance in the peak of the mass spectrum of a standard substance of each second substance, a total sum of an estimated strength of the peak B calculated at a predetermined time interval based on a strength of the peak A and the relationship F is subtracted from a strength of a peak C of a mass spectrum of the first substance in the specimen, thereby calculating a strength of a net peak D of the mass spectrum of the first substance.SELECTED DRAWING: Figure 10
Patent JP-2019123293-A (JP)
Title: Road surface state determination method and device
Inventor: MASAGO GO
IPC: B60W40/06
Filed: 2018-01-15
Abstract: To provide a method and device for surely and accurately determining a road surface with a less amount of a calculation amount.SOLUTION: A road surface state determination device 10 comprises: a front wheel side acceleration sensor 11 attached to a front wheel of a tire and detects a front wheel acceleration waveform; a rear wheel side acceleration sensor 21 attached to a rear wheel and detects a rear wheel acceleration waveform; feature amount calculation means 13, 23 for calculating a feature amount of a front wheel/rear wheel based on the front wheel acceleration waveform/rear wheel acceleration waveform; storage means 15 for storing a road surface feature amount determined for every road surface state in advance; and means 14, 24, 16 for determining a state of a road surface to which the front and rear wheels contact, based on the feature amounts calculated and the road surface feature amount. The means 14, 16 determines discrimination between a DRY road surface and WET road surface, means 24, 16 determines discrimination between a DRY road surface and ICE road surface, discrimination between a DRY road surface and SNOW road surface or discrimination between a DRY road surface and ICE/SNOW road surface.SELECTED DRAWING: Figure 1
Patent JP-2019126201-A (JP)
Title: Control device of electric vehicle
Inventor: SHIOZAKI JUNICHI
IPC: B60L15/20
Filed: 2018-01-17
Abstract: To provide a control device of an electric vehicle which can improve acceleration performance without the necessity for enlarging a motor and a battery, and raising performance.SOLUTION: In a control device of an electric vehicle having a gear transmission mechanism in which a torque transmission state is switched between a drive state that drive wheels are driven by motor torque outputted by a motor, and a driven state that the motor is driven by torque transmitted from the drive wheel side, when the electric vehicle is accelerated, a drive force for the acceleration is increased by bringing the gear transmission mechanism into the drive state by eliminating the backlash of the gear transmission mechanism by increasing the motor torque to a positive side in a direction in which the drive wheels are driven after temporarily bringing the gear transmission mechanism into the driven state by increasing the motor torque to a negative side in which the drive wheels are braked (step S200; steps S201 to 210).SELECTED DRAWING: Figure 3
Patent JP-2019123408-A (JP)
Title: Container placement implement
Inventor: MIMURA KOHEI
IPC: B60N3/10
Filed: 2018-01-18
Abstract: To provide a container placement implement capable of appropriately supporting the container with a receiving member, as well as allowing the container to be taken out smoothly without being interfered by the receiving member.SOLUTION: In a container placement implement 10, turns of a tray 12 and a flap 13 are linked through a link member 14 between a deployed position and a retracted position, and meanwhile the flap 13 can be turned toward a direction separating away from the tray 12 beyond the deployed position without being linked with the tray 12. An elastic sheet member 56 is provided at an upper end 54 of the link member 14, so that the elastic sheet member 56 contacts an abutment part 45 of the flap 13 when the flap 13 turns beyond the deployed position, so as to apply an appropriate resistance against the turn.SELECTED DRAWING: Figure 6
Patent JP-2018082498-A (JP)
Title: Image encoder, image encoding method, image decoder and image decoding method
Inventor: SEKIGUCHI SHUNICHI
IPC: H04N19/157
Filed: 2018-01-19
Abstract: PROBLEM TO BE SOLVED: To provide an image encoder and an image decoder, which can reduce an amount of a memory to be used.SOLUTION: A prediction image of an encoded block is generated in accordance with an encoding mode determined for the encoded block, a difference image between the encoded block and the prediction image is compressed, compression data of the difference image is outputted, the compression data of the difference image is expanded, the difference image after expansion and the prediction image are added, a decoded image is generated, filtering processing on the decoded image is performed, a block distortion occurring in a boundary of the adjacent prediction block in the decoded image is removed, and offset to a reference value of a parameter for determining intensity of a filter is encoded to encoded data. A loop filter section 11 derives the parameter for determining the intensity of the filter in accordance with a condition whether the encoding mode corresponding to at least one of the adjacent prediction blocks to which the filtering processing is applied is an intra-prediction mode or not, and the parameter is used for processing to select one filtering processing from the plurality of different filtering processing.SELECTED DRAWING: Figure 1
Patent JP-2019129940-A (JP)
Title: Lock sewing machine
Inventor: SAWADA TAKUYA
IPC: D05B63/00
Filed: 2018-01-30
Abstract: To perform the detection of opening/closing of a looper cover and a side cover, and the detection of a thread passing switching state by using a single switch.SOLUTION: A lock sewing machine comprises: a looper cover detection member which is actuated by a looper cover making a transition from an open state to a closed state and moves from a non-switching position to a switching position, and which, at the switching position, actuates a switching member to switch a thread-passing mechanism to a sewing-possible state; a side cover detection member which is actuated by a side cover making a transition from an open state to a closed state and moves from a non-detection position to a detection position; and a lever which is connected to the looper cover detection member and the side cover detection member, and which makes a transition between a pressing state of pressing an actuation projection and a non-pressing state of not pressing the actuation projection according to the actuation state of the looper cover detection member and the side cover detection member. The lever is brought into the pressing state when the looper cover detection member moves to the switching position, and the side cover detection member moves to the detection position.SELECTED DRAWING: Figure 1
Patent JP-2018130014-A (JP)
Title: Battery charging method and apparatus
Inventor: HONG JIN-SEOK
IPC: H01M10/48
Filed: 2018-01-30
Abstract: PROBLEM TO BE SOLVED: To provide a method and an apparatus for charging a battery using a multi-step constant current system.SOLUTION: Provided are a method and an apparatus for charging a battery through a stage of determining a first charging section in which a current charging rate of the battery is located out of a plurality of predetermined charging sections determined on the basis of a functional relationship between an SOC of the battery and an OCV of a negative electrode of the battery and a stage of charging the battery for a first charging interval at a first charging rate corresponding to the first charging interval.SELECTED DRAWING: Figure 1
Patent JP-2019072453-A (JP)
Title: Downhill instrument
Inventor: MINEGISHI HIDENOBU
IPC: A63C17/06
Filed: 2018-02-01
Abstract: To provide a downhill instrument capable of implementing side slipping even on a field such as a lawn or grassy plain, enabling enjoyment in dynamically sliding down like snow skiing.SOLUTION: Roller skis RS comprise a pair of right and left units, a right side sliding down unit KR and left side sliding down unit KL. A front wheel caster angle αF is set so that the lower end side of a steering shaft 42 of a front wheel 20 is in front of the upper end side thereof. A rear wheel caster angle αR is set so that the lower end side of a steering shaft 142 of a rear wheel 120 is in front of the upper end side thereof. In the case of a player slides down, the right side sliding down unit KR and left side sliding down unit KL can become in an edging state in which each front wheel 20 turns to the inner side in a turning direction of a neutral state and each rear wheel 120 does not turn to the inner side in the turning direction of the neutral state and in a side slipping state in which each front wheel 20 turns to the outer side in the turning direction of the neutral state and each rear wheel 120 turns to the outer side in the turning direction of the neutral state.SELECTED DRAWING: Figure 8
Patent JP-2019134842-A (JP)
Title: Game machine
Inventor: OGURA TOSHIO
IPC: A63F7/02
Filed: 2018-02-05
Abstract: To enhance interest of a game by notification promoting operation.SOLUTION: A game machine can detect a player's first action and second action (step 270FS125), can give a first promotion notification promoting the first action and a second promotion notification promoting a second action (step 270FS123), cab execute action corresponding performance on the basis of either detection of the first action for the first promotion notification or detection of the second action for the second promotion notification (step 270FS126), can give a first frequency notification showing remaining frequency of the first promotion notification given in the prescribed period and can give a second frequency notification showing remaining frequency of the second promotion notification (step 270FS122), and can give the second frequency notification in place of the first frequency notification on the basis that a specific condition is satisfied after the first frequency notification is given.SELECTED DRAWING: Figure 8-1
Patent JP-2018065751-A (JP)
Title: Method for growing group iii nitride crystal
Inventor: HASHIMOTO TADAO
IPC: C30B29/38
Filed: 2018-02-06
Abstract: PROBLEM TO BE SOLVED: To provide a method for growing a group III nitride crystal.SOLUTION: The method for growing a group III nitride crystal comprises: growing a group III nitride crystal, such as GaN on both sides of a seed by an ammono thermal method to form an ingot; slicing the ingot into wafers; slicing a wafer including a first formation seed more thickly than the other wafers so as not to break the wafer including the first formation seed; and using a wafer including a first formation seed crystal as a seed for subsequent ammono thermal growth.SELECTED DRAWING: Figure 1
Patent JP-2019140241-A (JP)
Title: Capacitor
Inventor: ISHIHARA YUKA
IPC: H01G2/08
Filed: 2018-02-09
Abstract: To provide a capacitor which enables electrical insulation to be formed between electrode plates and a heat dissipation member at low costs.SOLUTION: In a capacitor, a capacitor element 2, electrode plates 3, 4, and a heat dissipation member 5 are housed in a case 6 and the case 6 is filled with a resin. The case 6 includes an insulation part 62 which is located between the electrode plates 3, 4 pulled to the outside of the resin and the heat dissipation member 5 and secures electric insulation between the electrode plates 3, 4 and the heat dissipation member 5. Further, an insertion hole 5c is provided at the heat dissipation member 5 and the insulation part 62 is inserted into the insertion hole 5c to position the heat dissipation member 5.SELECTED DRAWING: Figure 1
Patent JP-2018149275-A (JP)
Title: Medical guidance device having closed frame arc guide
Inventor: KATO TAKAHISA
IPC: A61B6/03
Filed: 2018-02-16
Abstract: PROBLEM TO BE SOLVED: To provide a medical guidance device in which occurrence of human errors in inserting medical instruments into a subject is reduced, and precision and accuracy of medical surgical operation can be improved.SOLUTION: A medical guidance device comprises: a base plate 2 comprising a base plate opening and a bottom face being worn to a subject; a movable ring 11 rotatably attached to the base plate 2; and a needle guide 21 comprising a ring frame 3 and an arc-shaped guide 4. The arc-shaped guide 4 is attached to the ring frame 3 in two ends of the arc-shaped guide 4, and comprises a guide surface to provide a reference surface for guiding the medical instruments. The ring frame 3 includes a needle guide detachably attached to the movable ring 11 concentrically so that a guidance surface may be rotatable with the movable ring 11 to the base plate 2.SELECTED DRAWING: Figure 4(b)
Patent JP-2019145598-A (JP)
Title: Holding device
Inventor: YAMAMOTO TAKASHI
IPC: H01L21/683
Filed: 2018-02-19
Abstract: To provide a holding device, which can suppress a singular point of a temperature, a high temperature or a low temperature, from being generated, and controls a temperature distribution on a first surface of a ceramic member.SOLUTION: The holding device comprises a ceramic member having a plurality of protrusions formed on a first surface, and holds an object on the first surface. The first surface includes a first surface area and a second surface area which are positioned at positions different from each other and include same number (two or more) of protrusions respectively. In a part without formed protrusions where the protrusions are not formed of the first surface area are formed at least either one of a recessed part which satisfies either one of the fact that the part has a depth less than a length in a first direction of the protrusion and the fact that the part has a depth above the length in the first direction of the protrusion and is formed in an acyclic shape when viewed from the first direction and a protruding part that has a protrusion length less than the length in the first direction of the protrusion and is formed in an acyclic shape when viewed from the first direction, where neither the recessed part nor the protruding part is formed in the part without formed protrusions.SELECTED DRAWING: Figure 5
Patent JP-2018104452-A (JP)
Title: Methods of reducing risk of cardiovascular disease
Inventor: CHARLES L BISGAIER
IPC: A61K45/00
Filed: 2018-02-19
Abstract: PROBLEM TO BE SOLVED: To provide: methods of lowering the plasma LDL-C levels in a patient who is on a stable dose of statin and has an LDL-cholesterol (LDL-C) level above a treatment goal; and methods of decreasing the patient's risk for developing coronary heart disease or having a recurrent cardiovascular event.SOLUTION: The methods comprise administering effective amounts of compounds represented by formula (I) such as baicalin. (In the formula, Rto Rare C-Calkyl, C-Calkenyl, or the like; Yand Yare -COOH, -CHOH, tetrazole, or -COOR; and Ris C-Calkyl, C-Calkenyl, or the like.)SELECTED DRAWING: Figure 1