baber/WOPTO huggingface dataset:
Patent NZ-578037-A (NZ)
Title: Humidifier including a device for regulating the degree of humidification of the air flow
Inventor: NADJAFIZADEH HOSSEIN
IPC: A61M16/10
Filed: 2005-09-15
Abstract: Apparatus is disclosed for supplying a mask (7) through which air flows with a regulated degree of humidification. The method of using the apparatus comprises: providing a water reservoir (4) configured such that the air circulates in contact with the surface of water within the reservoir is charged with humidity; providing a heating device (3) for heating the water in the reservoir by circulating an electric current; measuring an average intensity (Iav) of the current passing through the heating device; and controlling of said average intensity (Iav) relative to a reference value (62) Divided Out of 553865
Patent NZ-580313-A (NZ)
Title: Smac mimetic dimers and trimers useful as anti-cancer agents
Inventor: HANSON GUNNAR
IPC: A01N43/76
Filed: 2008-04-11
Abstract: The disclosure relates to small molecule mimics of the SMAC peptide (a second mitochondria-derived activator of caspases, which is a mitochondrial protein) that are dimer-like or trimer-like compounds having two or three amide-containing domains connected by a linker, typical examples of a dimer-like and trimer-like compounds are represented by formula (1) and (2) respectively as shown and described herein. These compounds are useful to promote apoptosis, and pharmaceutical compositions comprising such compounds are suitable for treating conditions including cancer and autoimmune disorders.
Patent NZ-581045-A (NZ)
Title: Building panels mounted to rails which are held on straps
Inventor: LAKE MAURICE
IPC: E04B1/343
Filed: 2009-04-30
Abstract: 581045 A building panel mounting system 10 comprising a rail attachment strap 20 connectable to a support structure 12, the rail attachment strap 20 extending along a longitudinal axis, the rail attachment strap 20 including one or more rail support brackets, a rail having a generally rectangular profile and supported on a bottom surface by one of the one or more support brackets, the rail extending in a direction which is generally perpendicular to the longitudinal axis, a rail attachment profile 40 having an engagement formation removably interlocking with the rail, and a building panel connected to the rail attachment profile 40. A connection location of the rail to the one of the one or more support brackets is variable along an axis which extends perpendicular to a front face of the support structure 12. The engagement formation includes a channel having a web and two arms extending generally perpendicular to the web. The web removably engages an upper surface of the rail, and the two arms are respectively positioned engaging two opposing side surfaces of the rail.
Patent NZ-585406-A (NZ)
Title: Device and method for clamping of a sail to a motorised furling device
Inventor: WALDHAUSER KURT
IPC: B63H9/10
Filed: 2008-10-10
Abstract: 585406 A method for automatically coupling and decoupling the luff (14) of a battened mainsail (1) is disclosed. Stackable luff holders (16) as the connecting link between the sail luff and mast guiding slides (3) are also disclosed, thereby allowing the now free sail luff to be reefed up by means of an in-boom furling boom (8) and allowing the battened mainsail to be hoisted and reefed by means of mast guiding slides.
Patent NZ-588619-A (NZ)
Title: Housing for a fluid flow meter
Inventor: MAY MARTIN PHILIP
IPC: G01F3/08
Filed: 2009-04-17
Abstract: 588619 A fluid flow meter comprising an outer casing having an inlet (11) and outlet (13) and flow connections adapted to be connected so that in operation fluid to be measured flows through the casing, and a mechanical flow measuring unit (12) disposed in the casing to measure the flow through the casing. The casing is of plastics material and in at least two parts (30, 32) which are permanently bonded or connected together (at 34, 36) to enclose the measuring unit. At least one of the casing parts bears upon the housing of the measuring means to seal the housing against the outer casing to resist flow leakage past the measuring means, thereby forming a sealable flow path from the inlet, through the measuring means housing, to an outlet.
Patent NZ-589029-A (NZ)
Title: Method for producing a wheat protein hydrolysate
Inventor: LYNGLEV GITTE BUDOLFSEN
IPC: A23J3/34
Filed: 2009-05-29
Abstract: Disclosed is a method for producing a wheat protein hydrolysate, comprising: a) adding to a composition comprising wheat protein an endopeptidase having at least 70% identity to SEQ ID NO: 1; and b) incubating so as to hydrolyse the wheat protein. Also disclosed is a wheat protein hydrolysate produced by the method and the use of the wheat protein hydrolysate in a food product.
Patent NZ-589536-A (NZ)
Title: Safe handling spraying device
Inventor: NISHIMURA TAKASHI
IPC: B05B7/32
Filed: 2008-10-20
Abstract: 589536 A spraying device comprising a reservoir having an air pump or an electric or automated compressor to pressurize the reservoir, an interior of the reservoir defining a first pressure chamber in which water 10 is contained, the reservoir being in fluid communication with and applying pressure to an external surface of a pliable container 12 within which a concentrated chemical product is contained along with a small quantity of air or oil, where the container 12 has a connecting nozzle at its bottom. The nozzle is operable on receipt of a needle of a hose. The hose extends to a mixing device 21. The mixing device 21 is in communication with a pipe drawing water 10 from inside the reservoir and with an outlet pipe having an actuating trigger and a spraying nozzle 27.
Patent NZ-590213-A (NZ)
Title: Blower for positive airway pressure respiratory device with annular seal on outer surface of blower to seal with outer casing and separate inlet from outlet
Inventor: KENYON BARTON JOHN
IPC: F04D25/12
Filed: 2008-06-05
Abstract: Annular seal 406 on the outer surface of the blower 10 is adapted to engage the outer casing 400 to support the blower with the casing and separate the inlet from the outlet of the blower.
Patent NZ-590330-A (NZ)
Title: Structural variants of anti-cd20 antibodies for improved therapeutic characteristics
Inventor: GOLDENBERG DAVID M
IPC: A61K39/395
Filed: 2009-07-21
Abstract: An anti-CD20 antibody with an improved characteristic selected from: a slower off-rate; slower antigen dissociation rate; higher CDC activity; higher ADCC activity; higher apoptotic activity; greater ability to induced cell death in vitro in the absence of cross-linking and greater ability to kill or inhibit the growth of CD20-positive cells in vivo. The antibody is improved by a method that substitutes an amino acid at Kabat position 101 in the third CDR sequence of the heavy chain. The CDR sequences of the unsubstituted antibody are light chain CDR sequences CDRL1 (RASSSVSYIH), CDRL2 (ATSNLAS) and CDRL3 (QQWTSNPPT) and heavy chain CDR sequences CDRH1 (SYNMH), CDRH2 (AIYPGNGDTSYNQKFKG) and CDRH3 (STYYGGDWYFNV). The substitution can be replacing the asparagine at Kabat position 101 with aspartate. The antibody can be veltuzumab. The antibody can be used for treating B-cell mediated immune disease, autoimmune disease, B-cell lymphoma and leukaemia, graft-versus-host-disease (GVHD), organ transplant rejection, immune haemolytic anaemia, allosensitisation and cryoglobulinaemia.
Patent NZ-592019-A (NZ)
Title: Compression clothing made of elastically resilient material, with alternating compressive and non-compressive areas
Inventor: LAMBERTZ BODO W
IPC: A41B11/02
Filed: 2009-10-26
Abstract: Compression clothing (1) to be worn on the skin (2), made of elastically resilient material. Compression means are provided in certain areas, and the areas with a compressive effect are arranged to alternate with areas without compression. The compression means are formed by webs (3) provided on the side of the compression means facing the skin. The webs are provided with a coating (7).
Patent NZ-593639-A (NZ)
Title: Agents that engage antigen - presenting cells through dendritic cell asialoglyco-protein receptor (dc - asgpr)
Inventor: BANCHEREAU JACQUES F
IPC: A61P37/00
Filed: 2008-02-02
Abstract: Disclosed is an ex vivo method for increasing the effectiveness of antigen presentation by an isolated antigen presenting cell comprising the step of providing an isolated dendritic cell asialoglycoprotein receptor (DC-ASGPR) specific antibody or functional fragment thereof to which an antigen is attached, the antigen characterized in that it comprises at least one bacterial, viral, fungal, protozoan or cancer antigen, wherein neither the antigen nor the DC-ASGPR specific antibody or functional fragment thereof is attached to a Cohesin or Dockerin; and contacting the isolated antigen presenting cell with the DC-ASGPR-specific antibody or functional fragment and antigen, wherein the antigen is processed and presented by the dendritic cell that has been contacted with the antibody.
Patent NZ-595441-A (NZ)
Title: Mobile monitoring method and device having sensors for measuring the speed, geometry, and images of passing vehicles
Inventor: HANISCH HARALD
IPC: B60R16/02
Filed: 2011-09-29
Abstract: A mobile monitoring device and method for monitoring vehicles is disclosed. The monitoring device includes a first sensor, a second sensor, a camera, and an evaluation device. The first sensor measures the speed of vehicles passing through a first detection range and provides a speed measurement value of a passage of a vehicle with a first time stamp. The second sensor at least indirectly measures the geometry of vehicles passing through a second detection range and provides a geometry measurement value of a passage of a vehicle with a second time stamp. The camera records images of vehicles passing through a third detection range and provides the image of each passage of a vehicle with a third time stamp. The evaluation device is connected to the camera and the first and second sensors. The evaluation device calculates, on the basis of the speed measurement value, the first time stamp, the first detection range, the geometry measurement value, the second time stamp and the second detection range, the place and time at which a passage of a vehicle is to be expected in the third detection range in order to determine a matching image on the basis of the third time stamp and third detection range.
Patent NZ-601550-A (NZ)
Title: Polyanionic multivalent macromolecules for intracellular targeting of proliferation and protein synthesis
Inventor: PAULUS FLORIAN
IPC: A61K47/48
Filed: 2011-01-31
Abstract: ABSTRACT - 601550 The disclosure relates to a hyperbranched dendritic polyanionic macromolecule of sulphated polyglycerol for targeted delivery of diagnostic and therapeutic effector molecules to the cytoplasm and nucleus of proliferating and activated cells. The disclosure also relates to compositions for targeting of intracellular molecules involved in proliferation and protein synthesis of activated cells using polyanionic multivalent macromolecules. In particular aspect, multiple sulfate groups linked to polyglycerol are specifically targeted to the cytoplasm and nucleus of proliferating and activated cells. Particularly disclosed is the use of a pharmaceutical composition comprising a compound of the formula P(OSO3-M+)n(L-G-E)m, wherein P is a polyol macromolecule in which a number n of hydroxyl groups is substituted by sulfate groups OSO3-M+, n being a number > 10, M is a cationic inorganic or organic counter ion to the anionic sulfate group, E is a diagnostic effector molecule selected from the group of fluorescent dyes or chelators for radioactive or paramagnetic metals or a therapeutic effector molecule selected from the group of cytostatics, anti-angiogenetic drugs, photosensitizers and siRNAs, L is a linker or spacer between P and E, G is a reactive group for the covalent attachment between L and E, and m is a number of 1-100, for the preparation of a medicament for treating a disease related to activated NF-kappaB and/or AP-1 and/or elevated synthesis of TGF-beta by intracellular uptake of the compound of the formula P(OSO3-M+)n(L-G-E)m into activated cells or proliferative cells and by inhibiting NF-kappaB and/or AP-1 and/or TGF-beta synthesis in said cells.
Patent NZ-605175-A (NZ)
Title: A mixer assembly
Inventor: CHAMBERS CHRISTOPHER PAUL
IPC: G05D23/13
Filed: 2011-06-28
Abstract: A fluid mixer assembly is disclosed. The mixer accommodates differences in pressure between two feed input water feeds (300, 400). The mixer includes a fluid controller with inlets to receive first and second flows and outlets to outlet those flows controlled in the same or different proportions responsive to its selected control. A manifold with an inlet and an outlet for each of the first and second flows and an inlet and at least one outlet for a mixed flow is also present. An apparatus interposed between the controller and the manifold provides flow paths from the outlets of the manifold each for a separate first and second flow to the respective inlet of the fluid controller, and converging flow paths of the controlled flows from the outlets of the flow controller to provide a mixed flow path into the inlet of the manifold. A venturi may receive a first flow of fluid and a second flow of fluid is introduced to the first flow of fluid near the venturi. The change in pressures induced due to the first fluid passing through a nozzle of the venturi at least in part affects the draw of the second flow of fluid. The venturi can serve several functions including but not limited to, a) at least in part mixing the two or more supply fluids, and b) at least in part compensating for pressure differentials in the supply fluids.
Patent NZ-618213-A (NZ)
Title: A crystalline form of cyclosporine a, methods of preparation, and methods for use thereof
Inventor: GORE ANURADHA V
IPC: C07K7/64
Filed: 2012-05-25
Abstract: The disclosure relates to a crystalline form of Cyclosporine A (abstract figure). The disclosure also relates a pharmaceutical composition comprising this form and the use of this form in the treatment of aqueous deficient dry eye state, uveitis, phacoanaphylactic edophthalmitis, or keratoconjunctivitis sicca (KCS) in an eye, comprising administering to a subject in need thereof cyclosporine A in crystalline form 2 in an ophthalmically acceptable carrier.
Patent NZ-624195-A (NZ)
Title: Improved method for manufacture of macrobeads
Inventor: SMITH BARRY
IPC: C12N11/04
Filed: 2013-01-30
Abstract: A method for forming a bead of agarose and cells is described. The method seeks to expedite the formation of viable cells entrapped in permeable media for use in diabetes therapy, cancer treatment, stem cell maintenance etc. The method comprises: forming a suspension of cells and agarose; forming the suspension into a bead; coating the bead in a second layer of agarose; dispensing the bead into an oil bath with a temperature gradient so that the bead sinks from high to low temperature.
Patent NZ-625179-A (NZ)
Title: Improved methods for processing biomass
Inventor: MEDOFF MARSHALL
IPC: C12P19/14
Filed: 2012-12-20
Abstract: Disclosed are methods for processing biomass materials that are disposed in one or more porous structures or carriers, e.g., a bag, a shell, a net, a membrane, a mesh or any combination of these. Containing the material in this manner allows it to be readily added or removed at any point and in any sequence during processing. Also disclosed is the addition of an additive such as, e.g., microorganism, a nutrient, a spore, an enzyme, an acid, a base, a gas, an antibiotic, or a pharmaceutical to the structure or carrier to convert the contained biomass into useful products.
Patent NZ-626535-A (NZ)
Title: Transdermal delivery system comprising buprenorphine
Inventor: HILLE THOMAS
IPC: A61P25/04
Filed: 2012-12-12
Abstract: Provided is a transdermal therapeutic system comprising: A) a buprenorphine-impermeable backing layer, and B) a buprenorphine-containing pressure-sensitive adhesive layer on said buprenorphine-impermeable backing layer, the adhesive layer comprising: a) at least one polymer-based pressure-sensitive adhesive, b) an analgesically effective amount of buprenorphine base or a pharmaceutically acceptable salt thereof, and c) a carboxylic acid selected from the group consisting of oleic acid, linoleic acid and linolenic acid, levulinic acid and mixtures thereof, in an amount sufficient so that said analgesically effective amount of buprenorphine is solubilized therein to form a mixture, and the carboxylic acid buprenorphine mixture forms dispersed deposits in the said pressure-sensitive adhesive, wherein said buprenorphine-containing pressure-sensitive adhesive layer is the skin contact layer. The polymer-based adhesive is based on polysiloxanes or polyisobutylenes. The transdermal system is used for the manufacture of a medicament for the treatment of pain where the system is applied to the skin for 168h aka 7 days aka 1 week.
Patent NZ-628130-A (NZ)
Title: Treatment of addiction and impulse-control disorders using pde7 inhibitors
Inventor: GAITANARIS GEORGE A
IPC: A61K45/06
Filed: 2013-05-07
Abstract: Disclosed is the use of an inhibitor of a phosphodiesterase 7 (PDE7) and a dopaminergic agent in the manufacture of a medicament for treating an addiction that is an addiction to an addictive substance or that is the practice of a compulsive behaviour associated with a primary impulse-control disorder or an obsessive-compulsive disorder.
Patent NZ-628880-A (NZ)
Title: Compositions and methods for treating or preventing pneumovirus infection and associated diseases
Inventor: COOK ROBERT O
IPC: C07D257/04
Filed: 2013-06-28
Abstract: The disclosure relates to crystalline polymorphic forms of MDT-637, selected from the group consisting of a crystal form of P-3 dihydrate, P-3 ethanolate, P-3 monohydrate, P-3 anyhydrous, P-2 anhydrous, P-4, P-6, P-7 or P-8, or an amorphous form of P-3 dihydrate, P-3 ethanolate, P-3 monohydrate, P-3 anyhydrous, P-2 anhydrous, P-4, P-6, P-7 or P-8, in a carrier. MDT-637 has the chemical name: phenol, 2,2’-[(4-hydroxyphenyl)methylene]bis[4-[[(5-methyl-1 H-tetrazol-l-yl)imino] methyl]]; alternate name: 5,5’-Bis[1-(((5-methyl-1-H-tetrazolyl)imino)methyl)]-2,2\ 4”-methylidyne trisphenol; molecular formula C25H22N10O3 represented by the structural formula shown herein). The disclosure also relates to crystalline polymorphic forms with physicochemical properties specifically suited for drug production, amorphous formation, composite form, and methods of preparation thereof. The polymorphs described herein are useful for the treatment of respiratory disease, such as disease caused by respiratory syncytial virus.
Patent NZ-629568-A (NZ)
Title: Genetically modified animals and methods for making the same
Inventor: FAHRENKRUG SCOTT C
IPC: C12N15/85
Filed: 2013-06-19
Abstract: Disclosed are methods of making a genetically modified non-human artiodactyl or fish, said method comprising exposing embryos or primary cells to an mRNA encoding a TALEN, with the TALEN specifically binding to a target chromosomal site in the embryos or cells and inducing homology directed repair (HDR), cloning the cells in a surrogate mother or implanting the embryos in a surrogate mother, with the surrogate mother thereby gestating an artiodactyl or fish that is genetically modified without a reporter gene and only at the TALEN targeted chromosomal site.
Patent NZ-701824-A (NZ)
Title: Aptamer-based multiplexed assays
Inventor: SANDERS GLENN
IPC: G01N33/543
Filed: 2013-06-07
Abstract: The present disclosure describes methods, devices, reagents, and kits for the detection of one or more target molecules that may be present in a test sample. The described methods, devices, kits, and reagents facilitate the detection and quantification of a non-nucleic acid target (e.g., a protein target) in a test sample by detecting and quantifying a nucleic acid (i.e., an aptamer) where the aptamer-aptamer interactions are significantly reduced or eliminated while maintaining the aptamer-target interaction.
Patent NZ-702850-A (NZ)
Title: Inhaler device
Inventor: DEAMER JOHN
IPC: A61M15/00
Filed: 2013-07-04
Abstract: There is provided a reusable inhaler device in which movement of the inhaler housing lid from an ‘open’ position to a ‘closed’ position causes a punch to pierce the lid of a unit dose blister. The device comprises a housing, a mouthpiece, a seat for receiving a unit dose blister and a punch for piercing a lid of the unit dose blister. The housing comprises a base and a lid pivotally joined by a hinge, such that the lid is pivotable from a first ‘closed’ position in which it abuts the base to define a cavity, to a second ‘open’ position in which the cavity can be accessed. The seat and the punch are adapted to lie within the cavity when the lid is in the first ‘closed’ position and moving the lid from the ‘open’ position to the ‘closed’ position causes the punch to pierce a lid of a unit dose blister received in the seat. Only the lid of the unit dose blister is pierced. The device further comprises a unit dose blister retainer which holds the blister in a predetermined relationship with the housing base as the punch is withdrawn from the blister to ensure the blister is not retained by the punch after use so avoiding a potential misuse scenario.
Patent NZ-727833-A (NZ)
Title: Radar operation with increased doppler capability
Inventor: LEE ROBERT W
IPC: G01S13/95
Filed: 2015-05-26
Abstract: Pulsed Doppler radar systems have limits on unambiguous range and velocity capabilities, and are unable to characterize velocities present in severe weather events. Methods to extend the unambiguous velocity range using multiple pulse-repetition frequencies are unable to characterize the complex spectra encountered in tornadoes. A method, system and computer program product is provided for using reflections of wave energy from one or more reflecting objects to characterize certain properties of these objects through the spectral characteristics of the reflections from them. A repeating sequence of N constant-frequency pulses of width t seconds at interpulse intervals of T seconds is generated for transmission, with each pulse in the sequence having a particular constant phase according to a quadratic phase sequence, which phase is applied to each pulse in a first sense of modulation. The phase of echo energy received from one or more objects reflecting the transmitted repeating sequence of N constant-frequency pulses during each receiving subinterval by the identical quadratic phase sequence used for the transmitted repeating sequence of N constant-frequency pulses is modulated, with a second sense of modulation opposite to the first sense of modulation, so that the net phase modulation applied to echo energy reflected from a particular reflecting object at a particular range r, measured in discrete units of T of round-trip echo time, is a difference between the phase of the transmitted pulses at the time of their transmission and the phase applied to the received echo energy from range r, in either sense of the difference. Unique and discrete frequency translations of the received echo energy as a function of range r of the reflecting objects is produced from the modulated received echo energy N, of magnitude equal to multiples of 1/NT Hz, which frequency translations preserve the spectrum of the received echo energy, forming in combination a composite signal frequency spectrum. Echo-ranging of simple or complex objects is provided, whereby characteristics of echoes can be analysed in the spectral domain for use in radar and other echo-ranging systems.