baber/WOPTO huggingface dataset:
Patent DE-60315723-T2 (DE)
Inventor: GREGORY MATTHEW ALAN
IPC: A61K31/436
Filed: 2003-07-16
Granted: 2008-06-19
Abstract: The present invention relates to production of polyketides and other natural products and to libraries of compounds and individual novel compounds. One important area is the isolation and potential use of novel FKBP-ligand analogues and host cells that produce these compounds. The invention is particularly concerned with methods for the efficient transformation of strains that produce FKBP analogues and recombinant cells in which cloned genes or gene cassettes are expressed to generate novel compounds such as polyketide (especially rapamycin) FKBP-ligand analogues, and to processes for their preparation, and to means employed therein (e.g. nucleic acids, vectors, gene cassettes and genetically modified strains).
Patent DE-60315962-T2 (DE)
Inventor: YAMANO TORU
IPC: C07D213/55
Filed: 2003-03-05
Granted: 2008-05-29
Abstract: The present invention provides a method for producing an optically active  beta -hydroxy ester compound represented by the general formula: <CHEM> wherein R<1> represents an optionally substituted hydrocarbon group and the like, R<2> represents a nitrogen-containing heterocyclic group different from R<1>, which is represented by the general formula: <CHEM> wherein the ring may be substituted and the like, R<3> represents an optionally substituted hydrocarbon group and the like, R<4> and R<5> represent, the same or different, a hydrogen atom, a halogen atom and the like, the symbol "*" represents an optically active center, which comprises reacting in the presence of a cinchona alkaloid and the like a compound represented by the general formula: <CHEM> wherein R<1> and R<2> are as defined above with a compound represented by the general formula: <CHEM> wherein R<3>, R<4> and R<5> are as defined above, and X is a halogen atom.
Patent DE-68923286-T2 (DE)
Inventor: ANILIONIS ALGIS
IPC: C12Q1/68
Filed: 1989-08-31
Granted: 1996-03-07
Abstract: Peptides and proteins related to an epitope comprising an outer membrane protein of Haemophilus influenzae are described. The peptides and proteins can be prepared by methods including novel and improved methos of purification from H. influenzae cultures, and by recombinant DNA and chemical synthetic techniques. Additionally, recombinant vectors containing nucleotide sequences encoding PBOMP-1 and PBOMP-2 related peptides, proteins and fusion proteins are also described. Recombinant vectors include plasmid DNA and viral DNA such as human viruses, animal viruses, insect viruses and bacteriophages that direct the expression of the PBOMP-1 and PBOMP-2 related peptides, proteins, and fusion proteins in appropriate host cells. The peptides, proteins, fusion proteins and viruses both ''live'' and ''inactivated'' are used as immunogens in vaccine formulations to protect against H. influenzae infections. The peptides, proteins and fusion proteins are also used as reagents in immunoassays as well as to prepare immunoglobulins for passive immunization. Use of the nucleotide sequences encoding the PBOMP related peptides, proteins and fusion proteins in hybridization assays is also described.
Patent DE-68923752-T2 (DE)
Inventor: SWAVING ERLAND CHARLES JUSTUS
IPC: H01J29/04
Filed: 1989-09-18
Granted: 1996-04-11
Abstract: The invention relates to an electron gun comprising a cathode-unit composed of a cathode shaft 53 which is surrounded by a heat reflection screen 56. A connection piece 55 is secured to the head end of the cathode shaft 53. A holder 59 containing electron-emitting material 60 is located on the connection piece 55. The cathode shaft 53 is suspended in the heat reflection screen 56 by means of suspension wires 57, each wire being secured to the heat reflection screen with one end which is at least clsoe to the head end of the heat reflection screen 56; and the other end 58 being located between the connection piece 55 and the holder 59.
Patent DE-68927440-T2 (DE)
Inventor: HECK JOSEPH
IPC: H03L7/091
Filed: 1989-08-07
Granted: 1997-05-15
Abstract: A sample-and-hold type phase detector provides a linear positive or negative going ramp signal that may be used to linearly control a phase-locked loop over approximately a +/-360 DEG  phase range.
Patent DE-68928689-T2 (DE)
Inventor: SEAMONS JOHN K
IPC: G06F3/06
Filed: 1989-10-06
Granted: 1998-09-24
Abstract: In a computer system equipped with a magneto-optical disk drive having high data density, and therefore lengthy format times, and also requiring an erase step before each write operation, a system and method for decreasing user waiting time is provided. The system and method format the disk on a continuous basis during "disk-idle" periods rather than all at once. The system and method also erase disk portions belonging to deleted data in advance during disk-idle periods, so they are ready for the next write operation.
Patent DE-69004180-T2 (DE)
Inventor: HARRISON RAYMOND PETER
IPC: B67B7/86
Filed: 1990-07-26
Granted: 1994-05-05
Abstract: A spout is disclosed, for insertion into and securement to a plastic pouch. The spout comprises a tube (11) having a piercing portion (13) separated from a delivery portion (12) by a film securement portion (22) and having fluid flow communication from the piercing portion to the delivery portion. The film securement portion (22) is adapted to secure, with a substantially liquid-tight seal, plastic film which has been pierced by the piercing portion. The piercing portion (13) appears, in one perspective, to have been sliced at an angle to the longitudinal axis from a first location (23) at one side of said tube adjacent the film securement portion to a second location (14) at the other side of the tube, distal from the film securement portion, to form a tip (14) and to provide a slot (25) which aims to aid in draining material from the pouch, and the tip appears, in a second perspective perpendicular to the first perspective, to have been sliced symmetrically about the longitudinal axis of the tube to form a pointed piercing tip furthest away from the film securement portion (22). The contours of these slices are such that when the pointed tip (14) is pushed into the film, the force required remains substantially constant.
Patent DE-69005251-T2 (DE)
Inventor: VAN HOUDENHOVEN FRANCOIS EGBER
IPC: A61K35/39
Filed: 1990-09-17
Granted: 1994-05-05
Abstract: The present invention relates to sulphated glycosamino glycuronan with antithrombotic activity consisting essentially of salts of dermatan sulphate, chondroitin sulphate and heparan sulphate, characterized by     a) an average molecular weight between 4000 and 8000 daltons;   b) a nitrogen content between 2.4 and 3.0%;   c) a sulphur content between 7.5 and 9.5%;   d) a sodium content between 9 and 11%;   e) a dermatan sulphate content between 5 and 25%;   f) a chondroitin sulphate content less than 9%;   g) an anti-Xa activity between 11 and 20 u/mg; and h) an antithrombin III dependent antithrombin activity of less than 1 u/mg. p
Patent DE-69008876-T2 (DE)
Inventor: NOVEL PIERRE
IPC: H02G7/12
Filed: 1990-01-03
Granted: 1994-09-08
Abstract: According to the invention, the two jaws 2 and 3 are produced from an aluminium alloy possessing, on deformation, an extensive plastic phase and which are combined with articulated-lever clamping means capable of exerting on these jaws, at the end of the closing movement, a clamping force bringing, on clamping the conductor, their constituent material into its plastic deformation phase. <IMAGE>
Patent DE-69009835-T2 (DE)
Inventor: WALKER DAVID E
IPC: H02P5/69
Filed: 1990-04-09
Granted: 1994-12-08
Abstract: An electric motor drive system having a first electric motor 10, a first drive shaft 18 to which the first electric motor 10 is coupled, a second electric motor 20 having a higher power rating than the first, a second drive shaft 28 to which the second electric motor 20 is coupled, an epicyclic gear system 30 comprising a sun gear 32 to which the first drive shaft 18 is coupled, a ring gear 34 to which the second drive shaft 28 is coupled, and planetary gears 36 meshing with both the sun gear 32 and the ring gear 34, an output drive 40 coupled to the planetary gears 36, and, a one-way rotation restraining means 42 coupled to the second shaft 28 to permit rotation of the second shaft 28 in one direction and to prevent rotation of the second shaft 28 in the other direction for restraining motion of the second shaft 28 during start up of the first motor 10, and a one-way rotation restraining means 43 coupled to the first drive shaft 18 for restraining rotation of the first shaft 18 during start up of the second motor 20, and clutch means 60 operable to interconnect said first and second motors 10 and 20, during starting of one of said motor, to cause initial rotation of the other of said motors, and a method of operating such an electric motor drive system.
Patent DE-69009932-T2 (DE)
Inventor: STEINMETZ KLAUS
IPC: C04B37/02
Filed: 1990-10-31
Granted: 1994-10-20
Abstract: A composite abrasive compact comprising an abrasive compact bonded to a cemented carbide support is bonded to a metal-containing substrate such as a cemented carbide substrate or the working face of an abrasive or cutting tool using electrical resistance welding. Bonding is achieved between a surface of the cemented carbide support and a surface of the substrate.
Patent DE-69014464-T2 (DE)
Inventor: MATSUNAGA FUJIHISA
IPC: C07C269/06
Filed: 1990-07-24
Granted: 1995-05-11
Abstract: 4,4 min -Diphenylmethane dicarbamates are produced with high selectivity and in high yield by the one-stage condensation of a N-phenyl carbamate with a methylenating agent in presence of zinc halide as catalyst.
Patent DE-69015947-T2 (DE)
Inventor: MANSSON TORE
IPC: B63B27/25
Filed: 1990-10-04
Granted: 1995-08-24
Abstract: When handling bulk material a pressure vessel (10) including at least two members (11, 12) and provided with equipment for mechanically enclosing a portion of the bulk material is used. By means of pressure fluid from a conduit (17, 18) connected to the pressure vessel, a pneumatic evacuation of the enclosed material occurs by way of discharge conduit (20).
Patent DE-69019928-T2 (DE)
Inventor: SUZUKI SADAKATSU
IPC: C07C29/149
Filed: 1990-12-05
Granted: 1995-11-16
Abstract: There is disclosed a process for the production of 1,4-butanediol and tetrahydrofuran by the catalytic hydrogenation in the gas phase of gamma -butyrolactone using a solid catalyst comprising copper and silicon, copper, chromium, and manganese or copper, chromium, manganese and barium, the y-butyrolactone is preferably produced by the liquid phase hydrogenation of maleic anhydride.
Patent DE-69022952-T2 (DE)
Inventor: MATSUI SHIGETOMO
IPC: B28B1/30
Filed: 1990-10-30
Granted: 1996-05-30
Abstract: A tube (1) is formed from a polycrystalline silicon carbide having a density of from 3.18 to 3.21 g/cm<3>, a maximum impurity content of 20 ppm, and imperviousness to fluids by a process which comprises precipitating the silicon carbide (1a) on the surface of a rod-shaped graphite structure (G) by a chemical vapor-phase synthesis method and thereafter removing the graphite structure. A water-jet nozzle of high resistance to abrasive wear can be produced by using this tube as an inner tube thereof to form the flow path for a water jet to be ejected therethrough.
Patent DE-69023300-T2 (DE)
Inventor: NIETO ROBERT L
IPC: A61B5/151
Filed: 1990-08-24
Granted: 1996-04-18
Abstract: A lancet ejector device (60) for use in combination with a lancet injecting mechanism (10). The lancet ejector (60) of the present invention enables the user to eject a lancet (40) from the lancet injecting device without touching a used lancet.
Patent DE-69024067-T2 (DE)
Inventor: MUELLER WALTER BERNDT
IPC: B32B1/08
Filed: 1990-01-22
Granted: 1996-05-09
Abstract: A medical solution tubing (20) useful in combination with medical solution packages and pouches includes an intermediate layer (24) comprising a polymeric material which imparts flexibility to the film; an inner layer (26) comprising a heat resistant polymer; and an outer layer (22) of polypropylene, ethylene propylene copolymer, or modified ethylene propylene copolymer.
Patent DE-69025431-T2 (DE)
Inventor: EVERT CHARLES PETER
IPC: B32B7/02
Filed: 1990-06-12
Granted: 1996-08-14
Abstract: A tubular article formed of multilayer differentially cross-linked heat sealable film suitable for the manufacture of bags used in the packaging of meats. The multilayer film contains at least two layers the inner of which is a heat sealable layer containing an antioxidant cross-linking inhibitor in an amount sufficient to inhibit the cross-linking of that layer by irradiation. Accordingly, upon exposure of the multilayer film to radiation, the outer layer will be cross-linked to a greater extent than the first heat sealable layer.
Patent DE-69029470-T2 (DE)
Inventor: IOANNIS KARRAS
IPC: B60B7/14
Filed: 1990-11-09
Granted: 1997-06-26
Abstract: It's about a hub-cap for the magwheel of the car wheels, with special screw-tubes (3a, 3b) according to the empty space between the cap and the magwheel which fit the hub-cap on a fitting base (2). The base (2) has two screw-tubes (7a) which can be used independently straight to the cap (1).
Patent DE-69111601-T2 (DE)
Inventor: SCHINDLER ANTON
IPC: A61K47/30
Filed: 1991-05-01
Granted: 1996-03-28
Abstract: Random copolymers of caprolactone containing 5-25 mole-% trimethylene carbonate are shaped into tubular devices to form cylindrical capsules to be used for the sustained delivery of drugs after subcutaneous implantation in humans or animals.
Patent DE-69112589-T2 (DE)
Inventor: MIDDEL JAN
IPC: B07C5/04
Filed: 1991-12-20
Granted: 1996-02-08
Abstract: A process for sorting potatoes based on square size, in which the potatoes are passed through a V-shaped channel, and of each potato the distance between the point of the V-shape and the highest point of the potato is measured, and the square potato size belonging to the measured distance is determined. <IMAGE>
Patent DE-69122096-T2 (DE)
Inventor: PIRES PAUL B
IPC: F16D41/06
Filed: 1991-04-18
Granted: 1997-04-03
Abstract: A one way drive device, for example an overrunning clutch, is disclosed herein and includes a drive member and a driven member which are mounted for clockwise and counterclockwise rotation about a common axis. The drive member includes a planar drive face normal to the common axis and is adapted for connection with a source of power for rotating the planar drive face either clockwise or counterclockwise. The driven member includes a planar driven face which is positioned in close proximity to and in confronting relationship with the drive face. The drive and driven members are coupled to one another through a series of pockets in one of the drive or driven faces and a plurality of cooperating pawls carried by the other face such that when the drive member is driven counterclockwise, it drives the driven member with it an when the drive member is driven clockwise it does so freely, that is, without driving the driven member.
Patent DE-69126010-T2 (DE)
Inventor: PELEGRIN SOLA ENRIQUE
IPC: A61F2/36
Filed: 1991-12-17
Granted: 1997-11-20
Abstract: The insert -1- lacks any widening on the trochantereal part and the internal longitudinal hollow -2- has constant diameter throughout its length. A version with a rib -5- of scant relief on the trochantereal part has been envisaged. The insert has elasticity and power of recovery when it is pressed laterally in the direction of closing the slot -2a-. It requires a simpler and less traumatic operaion for the patient. <IMAGE>
Patent DE-69210177-T2 (DE)
Inventor: DOMANSKY PHILIPPE
IPC: B65D71/00
Filed: 1992-11-03
Granted: 1996-09-05
Abstract: A carton accommodating a plurality of articles has an internal keel structure (K) which protrudes inwardly of the carton to form a separator to space apart adjacent articles on either side of the keel structure. The keel structure comprises carton panel portions pairs arranged in spaced relationship with respect to each other. Each panel portion comprises bracing flaps effective to maintain the portions in an upstanding attitude and to create an article retention aperture with which wall portions of an article cooperates to resist dislodgment of the article from the carton. <IMAGE>
Patent DE-69213053-T2 (DE)
Inventor: HANSSON SOELVE
IPC: B23B5/12
Filed: 1992-03-03
Granted: 1997-01-16
Abstract: A tool for bar peeling of solid or hollow bars includes a rotatable cutter head (11) and a plurality of toolholders (12) distributed around its periphery. Each toolholder is provided with a roughing insert (14) and a distantly provided finishing insert (15). The edge surfaces of each roughing insert intersect with the top surface to define three separate curved cutting edges (16, 17, 18) whereby adjacent pair of edges intersect at angles, that preferably is 120-140 DEG . <IMAGE>
Patent DE-69221510-T2 (DE)
Inventor: WALTER JAMES FREDERIC
IPC: A01N65/00
Filed: 1992-01-01
Granted: 1998-02-19
Abstract: Novel pesticide formulations prepared from neem seeds are disclosed. Two distinct fractions are derived from non-polar, hydrophobic solvent neem seed extracts which are substantially free of azadirachtin, by removing the hydrophobic solvent and cooling the resulting neem oil to form a semi-solid neem wax fraction and a clarified neem oil fraction.
Patent DE-69224301-T2 (DE)
Inventor: CARPENTER LOREN C
IPC: H04H60/31
Filed: 1992-12-09
Granted: 1998-08-20
Abstract: An audience response system in which each audience member is provided with a reflective device (or other radiation source) which is, for example, green on one side and red on the other side. Light from a spotlight is reflected from the reflectors and imaged by a conventional video camera. A computer receives the digitized and processed image, forms a map of the audience, and distinguishes the red from the green reflections. This data is then used by the computer to project an image onto a screen visible to the audience, the image being controlled by the red or green image reflections. The audience thus jointly controls the screen image, for instance for purposes of voting or playing a game. The system also can detect movement (direction and/or velocity) of each radiation source which data is aggregated and thereby manipulates the screen image. Also, the sources each may transmit coded information (such as Morse code or ASCII) to individually identify themselves.
Patent DE-69325170-T2 (DE)
Inventor: RICHARDSON RICHARD
IPC: E06B3/00
Filed: 1993-02-23
Granted: 1999-09-23
Abstract: A refrigerator door construction is disclosed which includes door rail elements formed from a foamed polymeric substance. At least one substantially transparent panel is supported, retained by and sealed in the door rail. Connection elements are provided for connecting the door rail elements. At least one hinge is provided for allowing pivotal movement of the door about an axis. The foam rail element may also form one or more spacer elements between adjacent panels so that separate, discrete spacer bars may be eliminated.
Patent DE-69326949-T2 (DE)
Inventor: BRACCO UMBERTO
IPC: A23D9/00
Filed: 1993-08-20
Granted: 2000-02-17
Abstract: The fats in a food are partially replaced by a nutritional lipid composition. The fats in a food are partially replaced by a nutritional lipid composition in which: (1) triglyceride fatty acids comprise saturated fatty acids (up to 10 wt.%), monounsaturated fatty acids (50-70 wt.%) and polyunsaturated fatty acids (30-40 wt.%), (2) n-6 fatty acids make up 25-35 wt.% of the total fatty acids, (3) the weight ratio of n-6 acids to n-3 acids is 4.5-8.5:1, and (4) the polyunsaturated fatty acids comprise n-3 and n-6 fatty acids with a degree of unsaturation of at least 3. Independent claims are also included for the following: (1) a food in which the fats have been partially replaced by a nutritional lipid composition in which the average fatty acid composition of the principal triglycerides is (wt.%): C16:0 (3-8), C18:0 (1-5), C18:1 (50-65), C18:2 (20-35), C18:3 n-6 (gamma) (0.2-1), C18:3 n-3 (alpha) (1.5-4), C18:4 n-3 (0.1-0.5), C20:4 n-3 (EPA) (0.2-1), C22:6 n-3 (DHA) (0.1-0.8); (2) a process for producing a food as above in which the nutritional lipid composition is prepared by adding an antioxidant to an oil rich in monounsaturated fatty acids, mixing the various oils at up to 30 degrees C, and packaging the mixture under an inert atmosphere; and (3) whole milk in which the fats comprise anhydrous milk fat (50 wt.%) and the above nutritional lipid composition (50 wt.%).
Patent DE-69327083-T2 (DE)
Inventor: HANSEN CHARLES MEDOM
IPC: C09D5/00
Filed: 1993-09-09
Granted: 2000-05-25
Abstract: A method of producing an article with a coating having friction-reducing properties in wet condition, said coating comprising a binder (a), a hydrophilic polymer (b), as well as, if desired, an osmolality-increasing compound (c), whereby a dispersion is produced from (a) a binder in form of a hardenable prepolymer of a molecular weight of at least 200, (b) one or more hydrophilic polymers, (c) if desired, an osmolality-increasing compound, and (d) a solvent or a mixture of solvents, in which (a) is substantially insoluble, applying said dispersion onto the article, removing the solvent or a portion thereof, and hardening the binder, as well as a coating material for this purpose. A durable coating is obtained having good slide properties even after a long stay in an aqueous environment, such as within a body cavity.
Patent DE-69328610-T2 (DE)
Inventor: RAJARAM RAJ RAO
IPC: C01B32/50
Filed: 1993-12-06
Granted: 2001-01-11
Abstract: A reaction comprising the oxidation of carbon monoxide to carbon dioxide, eg in vehicle exhausts, employs a catalyst composed of metal oxide, eg ceria, particles among which are uniformly incorporated noble metal particles, the particles having such a high interaction that, without hydrogen reduction pre-treatment, the catalyst exhibits the formation of anionic vacancies on the metal oxide surface at a temperature lower than does the corresponding catalyst prepared by impregnation. The catalyst employed is preferably prepared by co-precipitation.
Patent DE-69330816-T2 (DE)
Inventor: KUZNICKI JOSEPH
IPC: H04J3/16
Filed: 1993-05-25
Granted: 2002-04-04
Abstract: A data communication terminal (102) transmits messages to a plurality of data communication receivers (106), and has an input for receiving messages and assigning the same into a plurality of transmission frames which are assigned for transmission to the plurality data communication receivers. The data communication terminal (102) comprises a first memory (210) for storing the received messages, a timer (214) for generating periodic timing signals, a controller (204) responsive to the periodic timing signals, for recovering the stored messages and queueing the same into a second memory (1910) having a predetermined transmission frame queue capacity. A monitoring circuit (1902, 1908) monitors the transmission frame queue capacity of the second memory (1910), and expected transmission frame queue capacities for one or more subsequent transmission frames. The monitoring circuit (1902, 1908) determines when the messages stored within the second memory (1910) will exceed the predetermined transmission frame queue capacity, and enables the storage of the excess messages in a third memory (1912). A frame batching controller (1902) generates designating information designating one or more of the subsequent transmission frames during which the excess messages stored are to be transmitted. A transmitter (104) transmits the messages and designating information stored in the second memory (1910) within the assigned transmission frame, and transmits the excess messages stored in the third memory (1912) within the one or more of the subsequent transmission frames designated by the designating information.