baber/WOPTO huggingface dataset:
Patent CY-1111638-T1 (CY)
Inventor: DIAKONOV YURI
IPC: A63B21/22
Filed: 2011-06-30
Abstract: An exercise barbell comprises a pair of rings connected by a pair of curved bars. The rings rotatably support handle members. Extensions of the bar on the exterior of the two rings support crescent-shaped weights which conform to the outer diameter of the ring and to one another. The weights are relatively flat so the entire apparatus lies in a single plane. A straight bar connecting the opposed sides of the two rings supports a sliding weight which may be moved to one side of the bar or the other to allow asymmetrical exercises.
Patent CY-1113087-T1 (CY)
Title: Ανθρωπινα αντισωματα εναντιον δελτα-παρομοιου προσδεματος 4
Inventor: PAPADOPOULOS NICHOLAS J
IPC: C07K16/22
Filed: 2012-09-04
Abstract: Απομονωμένο ανθρώπινο αντίσωμα ή θραύσμα ανθρώπινου αντισώματος που δεσμεύεται ειδικά με ανθρώπινο Δέλτα-παρόμοιο πρόδεσμα 4 (hDll4) και παρεμποδίζει την δέσμευση του hDll4 με υποδοχέα Notch. Το ανθρώπινο αντίσωμα ή θραύσμα αντισώματος αντι-hDll4 δεσμεύεται με hDll4 με συγγένεια ≤ 500 pM, όπως μετράται με συντονισμό επιφανειακών πλασμονίων.
Patent CY-1114590-T1 (CY)
Title: Εμβολια πεπτιδιου για καρκινους που εκφραζουν ογκο-συναφη αντιγονα
Inventor: TSUNODA TAKUYA
IPC: C07K14/745
Filed: 2013-11-08
Abstract: Η παρούσα εφεύρεση παρέχει πεπτίδια που έχουν αλληλουχία αμινοξέος όπως εκτίθεται στη SEQ ID NO: SEQ ΙD ΝΟ: 19, 22, 30, 34, 344, 358, 41, 44, 46, 48, 78, 376, 379, 80, 100, 101, 110, 111, 387, 112, 394, 114, 116, 117, 121, 395, 133, 135, 137, 426, 174, 178, 186, 194, 196, 202, 210, 213, 214, 217, 223, 227, 228, 233, 254, 271, 272 ή 288, καθώς επίσης πεπτίδια που έχουν τις ανωτέρω αναφερθείσες αλληλουχίες αμινοξέος, όπου 1, 2 ή μερικά (π.χ., μέχρι 5) αμινοξέα έχουν υποκατασταθεί, απαλειφθεί ή προστεθεί, υπό την προϋπόθεση ότι τα πεπτίδια έχουν κυτταροτοξική διεγερσιμότητα Τ κυττάρου. Η παρούσα εφεύρεση επίσης παρέχει φάρμακα για θεραπεία ή αποτροπή ασθένειας που συνδυάζεται με υπερ-έκφραση των CDH3, EPHA4, ΕCΤ2, ΗΙG2, ΙΝΗΒΒ, ΚIF20A, ΚΝΤC2, ΤΤΚ ή/και URLC10, π.χ. καρκίνων, που περιέχουν ως δραστικό συστατικό ένα ή περισσότερα από αυτά τα πεπτίδια. Τα πεπτίδια της παρούσας εφεύρεσης βρίσκουν περαιτέρω χρησιμότητα ως εμβόλια.
Patent CY-1118243-T1 (CY)
Title: Νεα κατασκευασματα μεταφορεα και μορια συζευγματος φορτιου μεταφορεα
Inventor: BONNY CHRISTOPHE
IPC: C07K14/16
Filed: 2016-11-09
Abstract: Η παρούσα εφεύρεση αφορά νέα κατασκευάσματα μεταφορέα του γενικού τύπου (I), DILLLxDm(LLLyDn)a και παραλλαγές αυτών. Η παρούσα εφεύρεση αφορά επίσης μόρια συζεύγματος φορτίου μεταφορέα, συγκεκριμένα συζεύγματα των νέων κατασκευασμάτων μεταφορέα με ένα τμήμα φορτίου, π.χ. πρωτεΐνες ή πεπτίδια, νουκλεϊκά οξέα, κυτταροτοξικούς παράγοντες, οργανικά μόρια, κτλ. Η παρούσα εφεύρεση επιπλέον αποκαλύπτει (φαρμακευτικές) συνθέσεις, οι οποίες περιλαμβάνουν αυτά τα συζεύγματα και μεθόδους αγωγής και χρήσης οι οποίες συμπεριλαμβάνουν τέτοια κατασκευάσματα μεταφορέα.
Patent CY-1120501-T1 (CY)
Title: Προερχομενα απο εζρινη πεπτιδια και φαρμακευτικες συνθεσεις αυτων
Inventor: HOLMS RUPERT
IPC: C07K7/08
Filed: 2018-03-26
Abstract: Η παρούσα εφεύρεση σχετίζεται με το πεδίο της ιατρικής, ειδικότερα, με το πεδίο της χημικής και φαρμακευτικής βιομηχανίας και αφορά προερχόμενα από εζρίνη πεπτίδια, ειδικότερα ένα πεπτίδιο που περιέχει μία αλληλουχία αμινοξέων του γενικού τύπου (I) Χ1 EKKRRETVERE Χ2Χ3, όπου κάθε Χ παριστά ένα υπόλειμμα μη πολικού αμινοξέος. Η χρήση των πεπτιδίων ως ανοσοδιεγερτικά μέσα και ειδικότερα για χρήση στη θεραπεία και την πρόληψη αντι-ιικών, αντιβακτηριακών και αντιμυκητησιακών λοιμώξεων και τη θεραπεία νόσων του ΓE σωλήνα, ειδικότερα ελκωδών διαταραχών του ΓE σωλήνα. Η παρούσα εφεύρεση σχετίζεται, επίσης, με φαρμακευτικές συνθέσεις που περιέχουν τα πεπτίδια. Επιπλέον, η εφεύρεση σχετίζεται με μεθόδους θεραπείας των μολυσματικών και ελκωδών νόσων του ΓE σωλήνα που περιέχουν τη χορήγηση των πεπτιδίων σε ασθενείς που το χρειάζονται.
Patent CY-1126136-T1 (CY)
Title: Μεθοδοι θεραπειας της αρθριτιδας
Inventor: HONG KEELUNG
IPC: A61K9/127
Filed: 2023-07-10
Abstract: Στο παρόν κείμενο περιλαμβάνονται μέθοδοι για την θεραπεία της αρθρίτιδας, οι οποίες περιλαμβάνουν τη χορήγηση μιας σύνθεσης παρατεταμένης αποδέσμευσης που περιέχει λιποσώματα τα οποία περιλαμβάνουν με τη σειρά τους ένα ή περισσότερα φωσφολιπίδια, χοληστερόλη, και έναν θεραπευτικό παράγοντα. Η σύνθεση παρατεταμένης αποδέσμευσης μπορεί να χορηγηθεί ενδοαρθρικά.
Patent GR-900300082-T1 (GR)
Title: Use of dapiprazole for the manufacture of a pharmaceutical composition inhibiting the development of tolerance in the analgesic treatment with morphine
Inventor: SILVESTRINI BRUNO
IPC: A61K31/495
Filed: 1991-07-31
Abstract: Use of dapiprazole for the manufacture of a pharmaceutical composition inhibiting the development of tolerance in the analgesic treatment with morphine of a subject in need of said treatment. Pharmaceutical composition comprising from 2 to 20 mg of dapiprazole
Patent HR-P20151418-T1 (HR)
Title: ANTIGEN BINDING MOLECULES WITH INCREASED Fc RECEPTOR BINDING AFFINITY AND EFFECTOR FUNCTION
Inventor: UMANA PABLO
IPC: C07K16/28
Filed: 2015-12-23
Abstract: The present invention relates to antigen binding molecules (ABMs). In particular embodiments, the present invention relates to recombinant monoclonal antibodies, including chimeric, primatized or humanized antibodies specific for human CD20. In addition, the present invention relates to nucleic acid molecules encoding such ABMs, and vectors and host cells comprising such nucleic acid molecules. The invention further relates to methods for producing the ABMs of the invention, and to methods of using these ABMs in treatment of disease. In addition, the present invention relates to ABMs with modified glycosylation having improved therapeutic properties, including antibodies with increased Fc receptor binding and increased effector function.
Patent SI-1558947-T1 (SI)
Title: X-ray backscatter mobile inspection van
Inventor: ADAMS WILLIAM
IPC: B60R/
Filed: 2003-11-03
Abstract: An inspection system based upon an enclosed conveyance (10) such as a van, capable of road travel, for inspecting objects of inspection that may include persons. The conveyance is characterized by an enclosing body, or skin. A source (30) of penetrating radiation and a spatial modulator (34) for forming the penetrating radiation into a beam, both contained entirely within the body of the enclosed conveyance, irradiate an object (12) with a time-variable scanning profile. A detector module (100) generates a scatter signal based on penetrating radiation scattered by contents of the object, while a relative motion sensor (18) generates a relative motion signal based on a relative disposition of the conveyance and the inspected object. An image is formed of the contents of the object based in part on the scatter signal and the relative motion signal. A detector, which may be separate or part of the scatter detector module, may exhibit sensitivity to decay products of radioactive material.
Patent SI-1618092-T1 (SI)
Title: Aryl-substituted pyrazole-amide compounds useful as kinase inhibitors
Inventor: DYCKMAN ALARIC
IPC: A61K31/4439
Filed: 2004-05-03
Abstract: The present invention provides pyrazole derived compounds of formula (I)   
useful for treating p38 kinase-associated conditions, where W, X, R 1 , R 2 , R 3 , R 4 , R 5 , R 6  and m are as defined herein. The invention further pertains to pharmaceutical compositions containing at least one compound according to the invention useful for treating p38 kinase-associated conditions, and methods of inhibiting the activity of p38 kinase in a mammal.
Patent SI-1721056-T1 (SI)
Title: Gluing construction
Inventor: VOGLER THOMAS
IPC: E05D15/00
Filed: 2005-02-23
Abstract: An adhesive system including a structural component to be mounted to a base structure, the structural component having a first bonding location and a second bonding location. The adhesive system also includes a primary bonding applied to the first bonding location of the structural component to bond the structural component to the base structure, the primary bonding comprising an adhesive of a sufficient strength to securely bond the structural component to the base structure; and a secondary bonding applied to the second bonding location of the structural component to bond the structural component to the base structure, the secondary bonding comprising an elastically stretchable adhesive.
Patent SI-2828287-T1 (SI)
Title: Methods for refolding g-csf from inclusion bodies
Inventor: FELFOLDI FERENC
IPC: C07K14/00
Filed: 2013-03-18
Abstract: New methods for the refolding of recombinant granulocyte colony stimulating factor (G-CSF) from inclusion bodies are disclosed. The methods comprise two refolding steps. In particular, the methods comprise the solubilising of G-CSF with a solubilising agent, the oxidative refolding (first refolding step) of G-CSF in the presence of the solubilising agent and an oxidizing agent, the efficient removal of the solubilising agent, and a second refolding step to complete the folding of G-CSF in the absence of the solubilising agent. Various methods are described for the efficient removal of the solubilising agent from partially refolded G-CSF.
Patent TR-200002734-T1 (TR)
Title: Kayıt taşıyıcı ve kayıt taşıyıcının taranması için aygıt
Inventor: VLERKEN JOHANNES J L M VAN
IPC: G11B27/19
Filed: 2000-01-11
Abstract: Kanal bitleri cinsinden ifade edilen uzunluklara sahip olan isaretler tarafindan temsil edilen bilgi bloklarinin kaydedilmesi için amaçlanan bir bilgi izine isaret eden bir servo izini içeren bir kayit tasiyici anlatilmistir, bu servo izi bir fiziksel parametrenin bir periyodik farklilasmasina sahiptir. Periyodik farklilasma adresler gibi kayit tasiyici bilgilerin kodlanmasi için modüle edilmektedir. Modülasyon, kayit tasiyici bilgilerinin bir veri bitinin önceden saptanmis sayida bir birinci fazda farklilasma, sonra, birinci fazin tersi bir ikinci fazda ayni sayida  farklilasma ile kodlandigi bir iki-fazli modülasyondur. Bir kayit ve/veya çaldirma cihaz, bir birinci fazda önceden saptanmis sayida farklilasma, sonra, birinci faza ters bir ikinci fazla ayni sayida farklilasmadan kayit tasiyici bilgilerinin veri bitlerinin çekilmesi için bir demodülatöre sahiptir.
Patent TR-200502310-T1 (TR)
Title: Mikrodalga kullanılan bir yıkayıcı/ kurutucu ve kontrol yöntemi.
Inventor: KURAL CEM
IPC: D06F33/74
Filed: 2003-12-22
Abstract: Bu buluş, bir mikrodalga uygulayıcı (2) yardımıyla mikrodalga kullanan, bir mikrodalga detektörü (7) ve bir metal detektörü (8) içeren bir yıkayıcı / kurutucu (1) ve yıkayıcı / kurutucunun (1) mikrodalga detektörü (7) ve metal detektörü (8) ile birlikte emniyetli olarak kullanılmasını sağlayan bir kullanım yöntemi ile ilgilidir.
Patent TR-201515579-T1 (TR)
Title: Fermuarlar için bileşen, fermuar ve fermuarlar için bileşenin üretim yöntemi.
Inventor: KAZUYA MIZUMOTO
IPC: A44B19/42
Filed: 2013-06-13
Abstract: Mevcut buluş, takviye elyafı içeren bir polyamid reçine bileşiminden oluşan bir kalıplanmış bileşen içeren, fermuarlar için bir bileşen sağlamakta olup, burada kalıplanmış bileşenin bir yüzeyinden içe doğru boya aplike edilen bir boya aplikasyonlu tabaka yer almaktadır ve boya aplikasyonlu tabakanın kalınlığı 30 ila 100 mikrometre arasındadır.
Patent DE-3686989-T2 (DE)
Inventor: DAVIDSON EVAN E
IPC: G01R31/28
Filed: 1986-08-08
Granted: 1993-04-22
Abstract: A test system having improved means for reducing driver switching (delta I) noise. The test system employs a tester connected to and electrically testing an integrated circuit device, such as a logic chip. The integrated circuit device has a plurality of input terminals (R5-R54) for receiving an electrical test pattern from the tester. The integrated circuit device also includes a plurality of output driver circuits (D2-D1O2) having outputs connected to the tester. The test system is characterized in that said integrated circuit device includes a driver sequencing circuit (L1-L1O) responsive to at least one control signal (R1-R4) from said tester to sequentially condition said driver circuits for possible switching, whereby delta I noise is reduced during testing.
Patent DE-3751341-T2 (DE)
Inventor: HADLEY MAXWELL RICHARD
IPC: G06F7/68
Filed: 1987-03-02
Granted: 1995-10-12
Abstract: This invention relates to apparatus for producing a periodic output signal having a predetermined period ratio a/b relative to a periodic input signal.Signals from a tachometer on a gearbox are received by a counter timer unit (11), the counter timer unit evaluates the number of clock pulses k° received from a clock (10) within each period of the tacho signal. A control unit receives values of k° from the counter timer and employs an algorithm based on the following equation to calculate a count value n° to be loaded into a register (30) for the next tacho period.where dK represents k<sup>-1</sup> - k°.An accumulator (17) is connected via an adder (31) to the register (30) and at receipt of each clock pulse from the clock (10) adds the count stored in register (30) into the accumulator (17. An output is produced on line (34) when the accumulator (17) overflows.
Patent DE-3751862-T2 (DE)
Inventor: KIRCHGESSNER DAVID A
IPC: B01J20/04
Filed: 1987-11-11
Granted: 1996-11-28
Abstract: A sorbent is provided for removing sulphur-containing gases from fossil fuel-fired combustors which is a lignosulfonate-modified material comprising calcium hydroxide and/or calcium magnesium hydroxide and an alkali metal lignosulfonate. The sorbent may be introduced downstream of the flame zone of the combustor.
Patent DE-3752212-T2 (DE)
Inventor: CHANDLER CURTIS SEPHUS
IPC: H01R13/658
Filed: 1987-12-16
Granted: 1999-02-11
Abstract: An electrical connector (4) includes a plurality of electrical terminals situated in an insulating housing (5), and the housing (5) is surrounded by shielding means to form a shielded subassembly. The latter is housed within a premolded boot (120) to form the electrical connector (4) which is interconnectable to shielded cable (180). The shielding means comprises first and second shield members (70,100) assembled to the insulating housing (5) and retained in position by windows (84) in the first shield member (70) engaging with ribs (20) on the housing, in conjunction with tabs (104,108) on the second shield member (100) engaging with the first shield member. <IMAGE>
Patent DE-3786930-T2 (DE)
Inventor: POWERS RICHARD
IPC: A23L35/00
Filed: 1987-11-06
Granted: 1993-11-18
Abstract: A conversion device is provided which permits an existing self-contained meat patty forming machine to be adapted for use with a separate, high capacity meat pump, so as to increase the output capacity of the patty former. The conversion structure includes an elongated, apertured meat delivery tube adapted to be used in lieu of an existing pivotal valving tube provided with the original machine, together with an accumulator coupled to the delivery tube. Operation of the separate pumping assembly is governed by that of the accumulator, and, ultimately, the operation of the patty forming apparatus. In this fashion the speed of the separate pumping assembly can be matched with that of the patty former so as to maintain continuous, trouble free operation.
Patent DE-3885069-T2 (DE)
Inventor: MAZANY ANTHONY MICHAEL
IPC: H01F1/04
Filed: 1988-12-13
Granted: 1994-03-10
Abstract: The present invention relates to an oxidation resistant composition for a rare earth magnet or magnet materials, comprising: an amino containing silane, and at least one of the following two compounds,  (1) an epoxy silane,  (2) an epoxy resin, the amount of any one of said three compounds in said two component composition being from about 20 parts to about 80 parts by weight based upon the total parts by weight of said two component composition, and wherein the amount of said remaining compound is from about 80 parts to about 20 parts by weight, based upon 100 parts by weight of said two component composition; and the amount of said amino containing silane and said epoxy silane in said three component composition being from about 5 to about 70 parts by weight per 100 parts by weight of said three component composition, and the amount of said epoxy compound being from about 5 parts to about 90 parts by weight per every 100 parts by weight of said three component composition, and the therewith obtained rare earth magnet or magnet material coated with said oxidation resistant composition.
Patent TR-199801252-T2 (TR)
Inventor: RAYMOND DALLAIRE
IPC: E06B7/14
Filed: 1996-12-23
Abstract: Yanlamasina kaydirilan kapaklar için, özellikle avlu kapilari ve benzeri kapilarda oldugu gibi sabit bir esik kismi olan yanlamasina kaydirilan kapaklar için drenaj sistemi açiklanmis bulunmaktadir. Drenaj sistemi, bir üst tavani karsisinda kenar yanlarinda yan duvarlarin belirledigi bir drenaj deligi olan kapak düzenini içermektedir. Drenaj deligi, olagan olarak, suyun kapak düzeni içerisinden akmasina olanak veren ancak disaridan havanin içeriye girmesini engelleyen bir kanat parçasi ile kapali tutulmaktadir. Kapak düzeni sabit bir ray içerisinden kesilmis bir drenaj yarigi üzerine monte edilmis bulunmaktadir. Drenajin çalismasinin en etkin sekilde olmasini saglamak için, sabit rayin açilmasi gerekmektedir. Sabit parmaklikta hava deligi açilmasi tercihen, sabit parmaklik için olagan olarak kullanilan uç basliklarinin sabit parmaklikta iç hava basincini büyük ölçüde atmosfer basincinda tutan yarikli uç basliklari ile degistirmek suretiyle gerçeklestirilmektedir.(DEVAMI VAR)
Patent TR-199901662-T2 (TR)
Inventor: SCHROCK ALAN K
IPC: C08G18/48
Filed: 1998-01-13
Abstract: Bu bulus, basinca karsi hassas bir yapiskan katina sahip esyalarin hazirlanmasinda faydali, poliüretandan imal edilen basinca karsi hassas bir yapiskan bilesimidir. Bu bulusun basinca karsi hassas yapiskan bilesimi, suyla veya seçime bagli olarak bir deterjan çözeltisiyle yikanabilir ve daha sonra kurutulduktan sonra baslangiçtaki yapisma gücünün en azindan %60'ini geri kazanabilir.
Patent TR-199902826-T2 (TR)
Inventor: BARNDT RICHARD L
IPC: A23L27/30
Filed: 1998-03-31
Abstract: This invention relates to a low calorie, palatable fiber-containing, sugar substitute composition suitable for use as a substitute for table sugar (for use on cereals, fruits, in hot or iced tea and coffee, etc.) and in the preparation of baked foods and other prepared solid and semi-solid foods.
Patent DE-60001495-T2 (DE)
Inventor: TJIOE TJIEN
IPC: C07D251/60
Filed: 2000-03-02
Granted: 2003-12-18
Abstract: Method for preparing melamine from urea via a high-pressure process in which solid melamine is obtained by transferring the melamine melt to an expansion vessel where the melamine melt is cooled by incorporated ammonia. Excess ammonia gas is added to the melamine melt to produce a gas/liquid mixture having a mass ratio of at least 0.01. This two-phase mixture is then sprayed via a spraying means into an expansion vessel, the expansion vessel having an ammonia environment with a reduced ammonia pressure. The melamine melt is cooled and solidified by the expansion and evaporation of the incorporated ammonia to form melamine powder. The melamine melt is thereby directly converted into a melamine powder after which the melamine powder is cooled further and the ammonia pressure is released.
Patent DE-60002070-T2 (DE)
Inventor: LANGEMAAT WILLEM
IPC: B65B13/04
Filed: 2000-06-22
Granted: 2004-02-26
Abstract: An apparatus for applying a banderole around one or a plurality of products creating an electrostatic attraction between the band material being supplied and the conveyor unit. The conveyor unit is connected to earth potential, and electrodes are positioned in the vicinity of the trajectory to be followed by the band material.
Patent DE-60006411-T2 (DE)
Inventor: WATKINS ANTHONY
IPC: G07C9/00
Filed: 2000-09-19
Granted: 2004-11-11
Abstract: An apparatus is described for counting the number of people crossing from one side of a given threshold to the other. The apparatus comprises a plurality of sensing means (10) for mounting above the threshold, each capable of detecting an item passing beneath it. Processing means compare the detection signals of each pair of adjacent sensing means to prevent the same person from being counted separately by the adjacent sensing means.
Patent DE-60007653-T2 (DE)
Inventor: NOORD JAN
IPC: G01G19/16
Filed: 2000-10-18
Granted: 2004-12-23
Abstract: The invention relates to an apparatus for manipulating in the height and in particular setting down of a load. The apparatus comprises a suspension on a lifting device, which suspension comprises a drive, with which drive the load can be manipulated in the height; a weighing device with which the weight of the load can be determined; a memory connected to the weighing device for storing an initial weight of the load; and comparing means for comparing an actual weight with the initial weight stored in the memory for the purpose of selective energizing of the drive in response to the comparison.
Patent DE-60012105-T2 (DE)
Inventor: MAURIN VERONIQUE
IPC: A61K8/46
Filed: 2000-09-26
Granted: 2005-07-28
Abstract: Anti-dandruff composition contains an acrylic terpolymer comprising 1-6C alkyl (meth)acrylate monomer, heterocyclic vinyl containing a nitrogen or sulfur atom(s), (meth)acrylamide, mono- or di-1-4C alkylamino-1-4C alkyl (meth)acrylate or mono- or di-1-4C alkylamino-1-4C alkyl (meth)acrylamide and monomer from urethane. Anti-dandruff composition comprises a cosmetic medium, an acrylic terpolymer comprising: (a) 5-80 (15-70, especially 40-70) wt.% 1-6C alkyl (meth)acrylate monomer; (b) 5-80 (10-70, especially 20-60) wt.% heterocyclic vinyl containing a nitrogen or sulfur atom(s), (meth)acrylamide, mono- or di-1-4C alkylamino-1-4C alkyl (meth)acrylate or mono- or di-1-4C alkylamino-1-4C alkyl (meth)acrylamide; and (c) 0.1-30 (0.1-10) wt.% monomer from urethane produced by reacting a monoethylenically unsaturated isocyanate and a nonionic surfactant including a 1,2-butylene oxide/ethylene oxide block copolymer with terminal 1-4C alkoxy, an ethylenically unsaturated surfactant monomer obtained by condensing a nonionic surfactant and an  alpha , beta -unsaturated carboxylic acid (anhydride), a (meth)allyl ether of formula (III), and a urethane nonionic monomer produced by reacting a monohydric nonionic surfactant with a monoethylenically unsaturated isocyanate; and anti-dandruff agent(s) from: (1) benzethonium chloride, benzalkonium chloride, chlorhexidine, chloramine T, chloramine B, 1,3-dibromo-5,5-dimethylhydantoin, 1,3-dichloro-5,5-dimethylhydantoin, 3-bromo-1-chloro-5,5-dimethylhydantoin and N-chlorosuccinimide; (2) 1-hydroxy-2-pyridone of formula (I); (3) trihalocarbamides of formula (II); (4) triclosan ; (5) N compounds such as climbazole, ketoconazole, clortrinazole, econazole, isoconazole or miconazole; (6) antifungal polymers such as amphotricine B or nystatine; (7) selenium sulfides; and/or (8) sulfur, cadmium sulfate, allantoin, oil or wood tar, undecylenic acid, fumaric acid or allylamine. CH2CR1CH2OAmBnApR2 (III) R1 = H or CH3; A = propyleneoxy or butylenoxy; B = ethyleneoxy; n = 0-200; m, p = 0 or number smaller than n; R2 = at least 8C hydrophobic group; R3 = 1-17C alkyl, 2-17C alkenyl, 5-8C cycloalkyl, 7-9C bicycloalkyl, cycloalkyl(alkyl), aryl, aryl-1-4C alkyl, aryl-2-4C alkenyl, aryloxy-1-4C alkyl, arylmercapto-1-4C alkyl, furyl-2-4C alkenyl, 1-4C alkoxy, NO2, CN or halogen; R4 = H, 1-4C alkyl, 2-4C alkenyl, halogen, phenyl or benzyl; X = organic base or alkali(ne earth) metal; and Z = halogen or trihalo-1-4C alkyl. An Independent claim is also included for a process for treating wet or dry hair by applying the composition, then after a period of time rinsing with water.
Patent DE-60023318-T2 (DE)
Inventor: VAN WAGENEN C
IPC: C07D/
Filed: 2000-08-18
Granted: 2006-07-20
Abstract: Compound of formula (II) wherein X, Y, and Z are independently selected from the group consisting of N, O, S, C, and CO wherein at least one of X, Y, and Z is a heteroatom; Ar<1> and Ar<2> are independently selected from the group consisting of a heterocyclic or fused heterocyclic moiety and an aromatic moiety; act as antagonist at metabotropic glutamate receptors, and are useful for treating neurological diseases and disorders.