baber/WOPTO huggingface dataset:
Patent CA-2266050-A1 (CA)
Title: Piperazine derivatives
Inventor: BOETTCHER HENNING
IPC: C07D409/12
Filed: 1997-09-03
Abstract: A piperazine derivative of the formula I  (see formula I) in which R1 may be substituted pyridyl or phenyl, and R2 may be monosubstituted or unsubstituted pyridyl, pyrimidinyl or pyrazinyl or substituted phenyl. The piperazine derivative is a dopamine ligand with a selectivity for the D4 receptor and is suitable for the treatment and prophylaxis of states of anxiety, depression, schizophrenia, obsessions, Parkinson's disease, tardive dyskinesia, nausea and disorders of the gastro-intestinal tract.
Patent CA-2267964-A1 (CA)
Inventor: CAMPBELL RONALD W
IPC: E04B2/00
Filed: 1997-09-05
Abstract: A prefabricated framing unit (10) for constructing non-load-bearing walls and partition is disclosed. The framing units have vertical studs (14) which both pivot in respect to the horizontal members (12), to allow collapsing of the unit (10), and telescope to allow the unit to be raised to fit the space between ceiling and floor without measuring and cutting to height.
Patent CA-2270476-A1 (CA)
Title: Improved coating or sealing composition
Inventor: CHAUVETTE GAETAN
IPC: C09D7/12
Filed: 1996-11-01
Abstract: The present invention relates to a coating or sealing composition comprising:  (A) a material comprising: at least one agent adapted to form a coating or sealer, and at least one additive defining a chemical and/or a U.V. stabilizer and/or antioxidant; and (B) a volatile excipient in which the above ingredients are either dispersed or disolved.
Patent CA-2272700-A1 (CA)
Inventor: CHOW VINCENT Y
IPC: G01D21/00
Filed: 1997-11-25
Abstract: The present invention relates to a transmission method and device for efficient compression of digital data. The invention uses an optoelectronic coupler to receive light signals from a light transmitter at two bandwidths. A  modulated signal generator is coupled to the transmitter which converts voltage phase data signals to light signals. The data signals are modulated with a plurality of master profiles and subprofiles with different cycle time variations. The optoelectronic coupler has a pair of photodiodes. Light filters disposed on both diodes allow either the first or second bandwidth of light to pass. Conductors electrically couple the anode of the each photodiode to the cathode of the other photodiode which produce the voltage phase signal.  A signal receiver is connected to the coupler and decodes the voltage phase signal.
Patent CA-2274756-A1 (CA)
Title: Methods and pharmaceutical compositions for inhibiting tumour cell growth
Inventor: TONTONOZ PETER
IPC: A61K31/422
Filed: 1997-12-11
Abstract: Methods for inhibiting proliferation of a PPAR.gamma.-responsive hyperproliferative cell using PPAR.gamma. agonists are described.  Pharmaceutical compositions as well as methods for diagnosing and treating a PPAR.gamma.-responsive hyperproliferative cell are also described.
Patent CA-2274938-A1 (CA)
Title: Novel digital cryptography method by selector box
Inventor: SABBAN DANIEL
IPC: H04L9/10
Filed: 1998-10-09
Abstract: The invention concerns a cryptography method for data recorded in the form of bits on a medium by an arithmetic unit for processing input data m, for supplying output data m', comprising at least a data processing step whereby the arithmetic unit uses a function C¿k? (m) dependent on a key k. The function C¿k? (m) comprises a selector box M adapted for processing selector box input data (x¿1?, ..., x¿j?, ..., x¿r?) with r?2, where x¿1?, ..., x¿r? are bit blocks, to supply selector box output data, (y¿1?, ..., y¿j?, ..., y¿s?), s?2, where y¿1?, ..., y¿s? are bit blocks, said selector box which, when all selector box input data, except one, are fixed, produces for each selector box output data a value obtained by permutation of the value of the unfixed selector box input data.
Patent CA-2281175-A1 (CA)
Title: Sunroof opening for vehicle roof panel
Inventor: TAYLOR JOE E
IPC: B62D65/06
Filed: 1999-08-27
Abstract: A method of stamping and punching at several stations, an opening in a vehicle rood panel to provide for sunroof installation is described. A preformed recess is stamped into the top section of the panel to define a perimeter for a sunroof opening. The stamping of the preform comprises locating the roof panel in a stamping press beneath a press die where the die is aligned with the perimeter of the desired position for the sunroof opening.  The preform recess is stamped in the panel where the preform is characterized by having a first bend which defines the opening perimeter and comprises rounded corner portions interconnected a front, rear and two side edges. A downwardly extending flange which becomes a sidewall of the sunroof opening is provided and has a length at least equal to the depth of a sealed portion of the sunroof panel and a second bend extending opposite to the first bend for interconnecting flange to the base portion of the recess. At the subsequent stations the underside surface of the flange of the preform is used to locate the panel for further processing. Preferably, at a subsequent processing station an apparatus is provided for bending lip portions of the depending flange to facilitate insertion of the sunroof. The apparatus has floating backup blocks and stacked stripper block and die block to locate the opening and effect bending of the flange without distorting the precise location of the flanges to ensure a seal with the sunroof panel installation.
Patent CA-2283126-A1 (CA)
Inventor: DORMOY JEAN-ROBERT
IPC: B01J31/14
Filed: 1998-03-05
Abstract: La présente invention concerne une procédé pour la préparation de dérivés 2thiényl-éthylamine de formule générale (I) ainsi que leurs sels d'addition d'acide, dans laquelle R représente un atome d'halogène et R1 représente un groupement alkyle en C1-C4, caractérisé en ce que l'on fait réagir un dérivé thiénylglycidique de formule générale (II), dans laquelle M représente un atome de métal alcalin ou une fraction d'un atome de métal alcalino-terreux, avec un ester de phénylglycine, éventuellement sous forme d'un sel d'acide fort, de formule générale (III), dans laquelle R et R1 ont la même signification que précédemment, en présence d'un borohydrure de métal alcalin de la formule générale (IV): X-Y, dans laquelle X représente un atome de métal alcalin et Y représente un groupement de formule (a): -BH3CN ou (b): -BH(4- W)Zw, dans laquelle Z représente un reste d'acide carboxylique et éventuellement en présence d'un acide carboxylique en C1-C4, ce qui fournit le composé désiré sous forme de base libre que l'on peut traiter si nécessaire, avec un acide pour obtenir un sel d'addition de ce composé.
Patent CA-2286431-A1 (CA)
Title: Sealing mechanism and method for screening machines
Inventor: BALLMAN BRADY P
IPC: B07B1/46
Filed: 1999-10-14
Abstract: A screen frame and screen are secured into sealing engagement within a screening machine by a screen frame sealing mechanism and method which allows the user to simultaneously raise an entire side of the screen frame into sealing engagement. Advantageously, the entire screen frame can be raised into sealing engagement to prevent the escape of fine material being screened and avoid metal-to-metal contact during the screening process from a single location.
Patent CA-2288679-A1 (CA)
Inventor: MANN GEORGE FOBES
IPC: C12N5/10
Filed: 1999-03-17
Abstract: The object of the invention is a process for the production of virus in cell culture with high yield and low levels of contamination by cell proteins, the virus being appropriate to be used in the preparation of seed lots and vaccines. As used herein, the term "virus" means inactivated virus, attenuated virus and recombinant virus, including chimeric virus. The process comprises the steps of: (a) preparing a culture of cells which are permissive to the virus and acceptable as a substrate for vaccine production; (b) suspending the cells in a suitable medium followed by cell seeding at low densities; (c) incubating the cell culture at 30 to 40 ~C for an appropriate period of time;  (d) removing the medium from the cell culture of step (c) and inoculating with seed virus; (e) incubating the cell culture of step (d) at 25 to 40 ~C for an appropriate period of time; (f) removing the medium followed by washing the cells once or more times and replacing the medium; (g) incubating the cell culture of step (f) at 25 to 40 ~C for an appropriate period of time; (h) total or partial harvesting of culture supernatant containing virus with or without addition of stabilizer; (i) optionally, carrying out multiple harvests of virus containing medium, at any desired interval, by replacing the removed medium and re-incubating the culture for an appropriate period; (j) optionally, removing the cell debris and whole cells from the harvested virus;  (l) optionally, virus inactivation and; (m) storing the virus at -45 ~C or lower.
Patent CA-2289376-A1 (CA)
Title: Cargo bed attachment for trucks
Inventor: KARRER ROBERT B
IPC: B60J7/08
Filed: 1999-11-02
Abstract: The present invention provides a hinge which can be used to attach a cover made up of individual parts to a cargo bed of a pick-up truck. The hinge provides adjustments to accommodate variations in the cargo bed so that the cover can be placed on the bed and the parts of the cover located relative to one another to allow the parts to be opened and closed independently. The hinge includes a mechanism which permits lengthwise movement relative to the truck as the cover part is raised angularly about the hinge so that the part does not interfere with adjacent parts as the part is raised or lowered. A cover made up of several parts for attachment to a cargo bed of a pick-up truck is also provided.
Patent CA-2292659-A1 (CA)
Title: Charging method in a mobile telecommunication system
Inventor: LINKOLA JANNE
IPC: H04M15/00
Filed: 1998-06-15
Abstract: The charging principles regarding mobile calls can be improved by providing the mobile station with a locator object, which at certain intervals determines the cell in which the mobile station is currently located. Stored in the mobile station is also a list of areas permitting application of a special rate. The locator object monitors calls made from the mobile station.  When it detects that a call is being started, it checks whether the mobile station was in a special rate area at the time when its location was determined last. If this is the case, then the object will inform the network that the call is entitled to a special rate. As the last location function was executed just before the call setup was started, a special rate call is possible even if the mobile station has moved some distance into the area of a cell applying a normal rate. Placed in a billing centre is a billing object, to which the locator object sends data indicating whether the call was started from a cell or area where a special rate is applicable, as well as data identifying the call. The second object receives the billing records generated by the mobile switching centre, which also contain call identifying data, and compares the call-specific data in them with the data sent by the first object. In this way, the second object can find from the billing records the calls that are entitled to a special rate, regardless of whether the mobile station has moved during call setup from the original cell into a cell where another rate, e.g. a higher rate is applicable.
Patent CA-2293322-A1 (CA)
Inventor: SAWADA TAIICHI
IPC: E04B2/62
Filed: 1998-05-18
Abstract: A frame assembly for a building is disclosed. The frame assembly comprises broadly two vertically spaced horizontally extending frame members (12) interconnected by two horizontally spaced vertically extending frame members (11) thereby forming a rectangle. Each of the members has a central channel opening to one face of the member and two side channels which are positioned on each side of the central channel. The horizontal member has the base webs of the side channels removed at the ends thereof (18). By contrast the vertically extending member has the base web of the central channel removed at the ends thereof (8). The configured ends of respectively the horizontal and vertical members thereby provide complementary mating formations (19, 9) for the attachment of the horizontal (12) and vertical (11) members. Typically attachment of the horizontal (12) to the vertical (11) members occurs by means of fastening elements which extend in three mutually orthogonal axes thereby improving the axial and torsional load bearing properties of the frame assembly.
Patent CA-2293962-A1 (CA)
Inventor: VAN WIJNKOOP MAARTEN
IPC: C07F3/06
Filed: 2000-01-04
Abstract: A method for altering the ratio of isotopes of the metal of a metal alkyl, in that an amount of depleted or enriched metal alkyl in preferably liquid form is contacted with an amount of the metal of the metal alkyl or an alloy of that metal and is held in contact for some time. Preferably, particulate metal or alloy is used, and the metal alkyl and the metal or t:he alloy are contacted and held in contact at a temperature above room temperature. The metal alkyl and/or the metal or alloy can be moved while being held in contact.      The method is applicable in particular to diethylzinc and zinc.
Patent CA-2296070-A1 (CA)
Inventor: NISHIDA EISUKE
IPC: G01N33/573
Filed: 1998-07-03
Abstract: Disclosed is a substantially pure MAPK (mitogen-activated protein kinase) kinase derived from a verte-brate, which is activated by a stimulus induced by TNF-.alpha. and/or by a stimulation of Fas antigen, and which in turn activates SAPK/JNK, but does not activate p38; and also disclosed is a DNA coding for the same. By the use of the novel MAPK kinase and the DNA coding for the same of the present invention, it has become possible to screen a novel substance having the capability to treat or prevent diseases resulting from an excess activation or inhibition of a MAP kinase cascade, and also to provide a diagnostic reagent for such diseases.      In addition, the DNA of the present invention encoding the MAPK kinase can be used as a gene source for gene therapy. Further disclosed are a replicable recombin-ant DNA which comprises a replicable expression vector and, operably inserted therein, the above-mentioned DNA; a cell of a microorganism or cell culture, which is transformed with the above-mentioned replicable recombinant DNA; a polypeptide of a dominant negative form of the above-mentioned MAPK kinase and a DNA coding for the same; and an antibody capable of binding specifically to the above-mentioned MAPK kinase.
Patent CA-2296484-A1 (CA)
Inventor: MACPHERSON DAVID CLYDE
IPC: B23K26/04
Filed: 1998-07-17
Abstract: The present invention provides a method for measuring the surface profile of a sample (8), the method including directing light from a light source (2) through a beam splitter (6) to form two split beams, directing the split beams onto a sample surface (8) and a reference surface (10) respectively, reflecting the split beams back through the beam splitter (6); and directing the split beams towards an imaging system (12). The invention also provides a surface profiling apparatus for measuring the surface profile of a sample (8), the apparatus including a light source (2) for generating a source beam, beam splitting means (6) positioned in the path of the source beam for splitting the source beam into split beams, a reference surface (10), a sample surface allowing the split beams to traverse separate paths and return to the beam splitting means (6), reference surface positioning means (14) for positioning the reference surface, and viewing means (12) for imaging combined beams. The invention also provides an apparatus for calibrating a laser for the ablation of a material including the surface profiling apparatus of the invention.
Patent CA-2297092-A1 (CA)
Title: Computer-directed detection of paraproteins
Inventor: SCOLARI CAROLINE
IPC: G01N27/447
Filed: 1998-07-21
Abstract: Identification and quantification of paraproteins in a sample is achieved by Fourier analysis of mobility-based electropherograms obtained from capillary electrophoresis. The use of a computer algorithm to analyze capillary electrophoresis data, provides the clinician with methods of detecting levels of paraproteins in serum as low as 0.05 g/dL. Additionally, an individual paraprotein can be located on an electropherogram and used to monitor its increased or decreased production in an individual.
Patent CA-2300307-A1 (CA)
Inventor: MARTINI SCOTT ALAN
IPC: B32B7/04
Filed: 1998-08-07
Abstract: A disposable wiping article is disclosed having at least a first layer and a second layer. The first layer can comprise a web of nonwoven fibers. The second layer comprises a net like arrangement of filaments which extend between filament intersections. The first layer is intermittently joined to the second layer at discrete, spaced apart locations, wherein portions of the filaments intermediate the filament intersections are not bonded to the first layer. The wiping article can be premoistened and has a macroscopically three dimensional surface with elongated ridges, wherein at least some ridges extend across at least one filament of the second layer.
Patent CA-2301271-A1 (CA)
Title: Purification of a methanol stream
Inventor: JUBIN JOHN C JR
IPC: C07C45/83
Filed: 1998-07-27
Abstract: Acetaldehyde may be effectively removed from a contaminated methanol stream using a distillation method wherein a solvent stream comprised of a relatively heavy polar compound such as water or propylene glycol is utilized as an extractive distillation solvent. Following the separation of the polar compound from the bottoms stream obtained by extractive distillation, the purified methanol may be recycled for use as a reaction solvent in an olefin epoxidation process.
Patent CA-2301333-A1 (CA)
Title: Peptides de prb2/p130 inhibiteurs de l'activite kinase cdk2
Inventor: GIORDANO ANTONIO
IPC: C07K14/47
Filed: 1998-08-06
Abstract: La présente invention concerne des peptides de pRb2/p130 (voir figure) ou des mutants ou fragments de ceux-ci inhibant l'activité kinase cdk2. L'invention concerne également des procédés d'inhibition de l'activité kinase cdk2 dans des cellules à l'aide de ces peptides.
Patent CA-2302844-A1 (CA)
Title: Protege flamme pour bougie a huile
Inventor: BUREAU JACQUES
IPC: F23D3/18
Filed: 2000-03-27
Abstract: Le dispositif appelé « protège-flamme » sert à protéger la flamme d'une bougie à huile tout en augmentant la puissance et l'efficacité de cett e flamme. Le protège-flamme comprend une pièce de forme généralement tubulaire ayant une extrémité inférieure pourvue de crochets de fixation pou r l'attacher à la partie supérieure de la bougie à huile. Elle comprend aussi une extrémité supérieure s'étendant plus haut que la mèche de la bougie à huile lorsque le protège-flamme est fixé à la partie supérieure de la bougie à huile. Elle comprend enfin des ouvertures latérales près de l'extrémité inférieure.  Ces ouvertures latérales agissent comme prises d'air et assurant l'augmentation désirée de la puissance et de l'efficacité de la flamme. Avantageusement, le protège-flamme peut comprendre en outre un bouchon fixable au support supportant la mèche en vue de fermer celui-ci et éviter un écoulement d'huil e hors du contenant de la bougie à huile lors du transport de celle-ci. Ce bouchon est constitué de préférence par un tube creux pourvu d'une extrémité supérieure fermée, ce tube creux étant dimensionné pour s'insérer à serre su r le tube supportant la mèche en vue de recouvrir la mèche et fermer le tube l a supportant. Une attache est prévue pour relier le bouchon à même la pièce tubulaire. Cette attache consiste de préférence en une tige flexible s'étendant depuis l'extrémité supérieure du tube creux jusqu'à un crochet de fixation fixé à même la pièce tubulaire à l'extérieur de celle-ci.
Patent CA-2304985-A1 (CA)
Title: Lactobacillus helveticus bacterium having high capability of producing tripeptide, fermented milk product, and process for preparing the same
Inventor: YAMAMOTO NAOYUKI
IPC: A23C9/137
Filed: 1998-02-05
Abstract: There is provided a fermented milk product that contains lactic acid bacteria capable of producing a large amount of lactotripeptide and a large amount of active ingredient having hypotensive activity and anti-stress effect, and that can be taken pleasantly as foods or beverages. Lactic acid bacteria of Lactobacillus helveticus having specific bacteriological properties, the bacteria, when cultured in a medium of animal milk containing 9wt% solid of non-fat milk, producing tripeptides Val-Pro-Pro and Ile-Pro-Pro in an amount of 60µg in terms of Val-Pro-Pro per ml medium, and the bacteria exhibiting extracellular proteinase activity of not lower than 400U/OD590. Lactobacillus helveticus CM4 strain (deposited at National Institute of Bioscience and Human-Technology Agency of Industrial Science and Technology, deposition number FERM  BP-6060). A fermented milk product obtained by fermenting an animal milk with these lactic acid bacteria.
Patent CA-2305552-A1 (CA)
Title: Soft, strong hydraulically entangled nonwoven composite material and method for making the same
Inventor: SKOOG HENRY
IPC: D04H1/46
Filed: 1998-10-16
Abstract: A method of making a nonwoven composite material. The method includes the steps of providing a hydraulically entangled web containing a fibrous component and a nonwoven layer of substantially continuous filaments, applying a bonding material to at least one side of said web, and creping the at least one side of the hydraulically entangled web. The bonder material may be an aqueous mixture including a curable latex polymer, a pigment, and a cure promoter. Also disclosed is a nonwoven composite material made of a hydraulically entangled web including a fibrous component, a nonwoven layer of substantially continuous filaments, and regions containing bonder material covering at least a portion of at least one side of the composite material, where at least one side of the web has been creped.
Patent CA-2312124-A1 (CA)
Title: Optical recording medium and recording and/or reproducing method and apparatus employing the optical recording medium
Inventor: YASUDA AKIO
IPC: G11B7/1365
Filed: 2000-06-22
Abstract: An optical recording medium is capable of linear recording in a photon mode. An organic material changed in molecular orientation on light illumination to exhibit birefringence is used as a recording material. For example, a recording layer having, as a recording material, an organic material changed in molecular orientation caused by trans-cis rearrangement, is changed in birefringence with changes in the molecular orientation of the organic material. The recording system which utilizes the changes in the molecular orientation of the organic material has linear characteristics and gives outputs different depending on e.g., the degree or the angle of orientation, thus enabling multi-valued recording.
Patent CA-2312698-A1 (CA)
Inventor: NOZAKI CHIKATERU
IPC: C07K14/18
Filed: 1998-12-08
Abstract: L'invention concerne des oligonucléotides antisens complémentaires d'au moins une partie de l'ARN du virus de l'hépatite C (HCV) et pouvant s'hybrider avec au moins une partie de l'ARN du HCV, ces oligonucléotides étant par ailleurs capables d'inhiber la fonction de l'ARN du HCV. Ces oligonucléotides peuvent être administrés afin d'inhiber l'activité du virus de l'hépatite C in vivo ou in vitro. Ces composés, qui peuvent en outre être utilisés de manière prophylactique ou thérapeutique afin d'atténuer les effets des maladies liées au virus de l'hépatite C, peuvent par ailleurs permettre de diagnostiquer et de détecter les maladies dues au HCV ainsi que les maladies liées au HCV. L'invention concerne également des procédés d'utilisation de ces composés.
Patent CA-2313858-A1 (CA)
Title: Microporous films comprising flocked fibers
Inventor: DABI SHMUEL
IPC: A61Q19/00
Filed: 2000-07-11
Abstract: This invention relates to microporous films comprising flocked fibers. Such microporous films may be used as breathable materials in for example absorbent articles, wound care bandages, and skin care patches.