baber/WOPTO huggingface dataset:
Patent LV-13694-B (LV)
Title: Dismountable plate chain with rolling friction joint
Inventor: UZKLINGIS GUNTARS
Filed: 2008-01-11
Abstract: The invention relates to machine building, particularly to dismountable plate chains with rolling friction joints. In the offered technical solution the construction of the axle and plates is changed. In the axle plane surfaces a cam is made but a hole in the operational surface of the plate figural cut. The axle cam is in mesh with the plate in the total outer inner chain link turning angle range. The offered constructive chaugls ensure rolling of the axle and plate operation surfaces without harmful slipping. The way the formulated aim is achieved - increasing of chain application safety and operational life. The chain can bi used in conveyers that au used in industry well as in agriculture.
Patent LV-14753-B (LV)
Title: Method for producing casting moulds for pressure diecasting, particularly for casting aluminium alloy crosspiecies, and a pressure diecasting mould therefor
Inventor: VONHAUSEN MARCUS GEORG
IPC: B22D17/22
Filed: 2012-07-31
Abstract: The offered mould is a combination of a steel fixed mould section (1) and a steel movable mould section (2). Shape defining pieces are located in the fixed mould section (1) and the movable mould section (2). The surface of the shape defining piece in the fixed mould section (1) is shaped as a pentacle. A core (1c) protrudes from the fixed mould section. The bottom of the shape defining piece surface in the fixed mould section (1) is concave. The holes constituting the cooling runners (8) of the movable mould section (2) are distributed symmetrically on both sides of the arms (6). When the fixed mould section (1) is put together with the movable section (2), the outer edges of the moulding piece in the fixed mould section (1) adhere to the outer edges of the moulding piece in the movable mould section (2). Pockets (10) are present in the seat pit surface of the fixed mould section (1), and cooling runner holes (11) and attachment holes (12) pass through the wall of the fixed mould section (1). Cooling and moulding inserts (13) are set in the pockets (10) so that fragments of their surface constitute the fragments of the seat pocket surface in the fixed mould section (1). Cooling runners (13a) of the cooling and moulding insert (13) are present in the cooling inserts (11), with routes resembling a coil. The cooling runners (4) are hydraulically connected with the cooling runners (13a) of the cooling and moulding inserts (13). The cooling and moulding inserts (13) are immobilised in the fixed mould section (1).
Patent NO-134202-B (NO)
Inventor: TEGLE SVEIN
IPC: B65G/
Filed: 1974-06-19
Abstract: Bukk for anvendelse ved ifylling og fordeling av gress i en silo.
Patent NO-162478-B (NO)
Inventor: MATOLCSY GEZA A
IPC: D21F11/14
Filed: 1983-06-28
Abstract: A process and apparatus for the manufacture of high bulk paper, or a high bulk layer of a multi-layered paper, which uses a mixture of fibres in a paper-making bond forming state and substantially dry fibres. The dry fibres may be mixed with the conventional slurry of bond forming fibres shortly before the headbox. The web may be dried primarily by pressing, with the dry fibres remaining incompletely wetted throughout the process and ensuring a bulky product; through-air driers need not be used. The invention also covers the novel product of this process.
Patent NO-158552-B (NO)
Title: Enkeltvirkende hydraulisk aktuator for uttak av lagret fjaerenergi.
Inventor: HEIM EDGAR
IPC: E21B34/02
Filed: 1986-04-04
Abstract: Det er oppfinnelsens formål å tilveiebringe en fjærbetjent ventilaktuator for uttak av lagret fjærenergi hvor det ved bruk av et kompakt og lite plasskrevende fjærsystem kan etableres lukkekrefter som er nøyaktig tilpasset ventilmekanismens lukkekarakteristikk.Dette er oppnådd ifølge oppfinnelsen ved å benytte en robust fjærmekanisme med kort, særdeles kraftig lukkekarakteristikk, men hvor energien fra fjærmekanismen fordeles eller utveksles over ventilens totale lukkebevegelse eller slag og hvor energien eller kraftuttaket kan konsentreres til visse områder.Det nye og karakteristiske konstruktive trekk ved aktuatoranordningen som ifølge oppfinnelsen omfatter en fjærmekanisme og et bevegelig stempel, er at fjærmekanismen og stemplet står i mekanisk drivforbin-delse via en variabel utvekslingsanordning (3, 4, 10).
Patent NO-170335-B (NO)
Inventor: JEFSON MARTIN RAYMOND
IPC: C07D215/56
Filed: 1986-09-17
Abstract: Antibacterial compounds have the formula <CHEM> wherein R<1> is hydrogen, a pharmaceutically acceptable cation, or alkyl; A is CH, CF, CCl or N; Y is alkyl, haloalkyl, cyclopropyl, vinyl, methoxy, N-methylamino, p-fluorophenyl, p-hydroxyphenyl or p-aminophenyl; or A is carbon and is taken together with Y and the carbon and nitrogen to which A and Y are attached to form a five to seven membered ring which is optionally substituted; and R<2> is a bridged-diazabicycloalkyl group.
Patent NO-168841-B (NO)
Inventor: BOLLIAND ROBERT
IPC: D04H3/004
Filed: 1988-06-09
Abstract: The present invention relates to the needling of continuous glass fibre mats. 
<??>The invention consists in subjecting the mat to the action, preferably simultaneous, of needles of different diameters. Perforations of different sizes, preferably uniformly distributed, are thus produced in the mat. 
<??>This mat is intended to be employed as a reinforcement in composite materials based on thermoplastic resins, especially in laminates. 
<IMAGE>
Patent NO-167737-B (NO)
Inventor: RAEYMAEKERS ALFONS HERMAN MARG
IPC: C07D487/06
Filed: 1989-03-17
Abstract: Novel antiviral tetrahydroimidazo[1,4]benzodiazepin-2-ones of formula   <CHEM> a pharmaceutically acceptable acid addition salt or a stereochemically isomeric form thereof, wherein R<1> is hydrogen, C1-8alkyl, C3-6alkenyl, C3-6alkynyl, C1-6alkylcarbonyl, C3-6cycloalkyl, or substituted C1-6alkyl;  R<2> is hydrogen, C1-6alkyl or C3-6alkenyl  R<3> is hydrogen or C1-6alkyl; R<4> is hydrogen; substituted C1-6alkyl; C1-6alkylcarbonyl; C3-6alkenyl; C3-6cycloalkyl; C5-6cycloalkenyl;  R<5> is hydrogen, C1-6alkyl or halo; and  aryl is optionally substituted phenyl; pharmaceutical compositions containing these compounds as active ingredient; processes for preparing said compounds and compositions.
Patent SE-341209-B (SE)
Inventor: TANAKA T
IPC: H01B17/02
Filed: 1969-01-27
Abstract: 1,258,941. Insulators. NIPPON GAISHI K.K. 30 Jan., 1969 [13 June, 1968], No. 5232/69. Heading H2C. Gas pressure in a cement layer of a cap and pin insulator is released through holes formed in the pin or in the cement layer. Holes in the cement securing the pin may be provided by embedding rods of a material which burn away or melt as a result of the flashover. Such materials are synthetic resins (e.g. foam polystyrene) organic fibres, rubber metals (e.g. lowtemperature solder) or wood. The pin may be enlarged at the surface of the cement layer to prevent electrolytic action (Fig. 2A). Specification 1,025,554 is referred to.
Patent SE-326973-B (SE)
Inventor: KOOCH G
IPC: B41L45/00
Filed: 1967-04-27
Abstract: 1,176,183. Printing-apparatus; addressing machines. SCRIPTOMATIC S.A. 3 May, 1967 [4 May, 1966], No. 20536/67. Headings B6C. and B6D. [Also in Division B8] Ina hectographic addressing machine, a workpiece W, Fig. 4, such as an envelope, passes over a button 130 which actuates a first one-revolution clutch 84, Fig. 12a, which in turn actuates a second one-revolution clutch 83 after an adjustable time delay, the second clutch actuating a master card feed plate 123, Fig. 4, and solvent applying means S. Cylinder tripping.-The first clutch 84 comprises a solenoid 132 energized by depression of the button 130 to retract a core 133 and release the free end 84a of a coil spring in the first clutch 84, thus drivingly connecting a gear (91), Fig. 1 (not shown), driven by the drive train of the machine, to a coaxial notched wheel (135), Fig. 8, (not shown). A latch 136, Fig. 12a, adjustably mounted on the wheel (135), is thereby rotated and caused to engage a trigger arm 137 which releases the end 83a of a coil spring in the second clutch 83 and drivingly connects a gear (79, Fig. 1) to a shaft 80, Fig. 4. A :pin 106, mounted on the shaft 80, and which normally supports a solvent applying roller 105, is thus rotated, allowing the roller 105 to apply solvent to the workpiece W. After one revolution, the second clutch 83 disconnects the shaft 80 from its driving gear (79) and the pin holds the solvent applying roller 105 in non-operative position. Addressing &c. machines.-Rollers 76, 116 apply pressure to the assembly of a master card and moistened workpiece to print on the workpiece, the position of the printed image on the workpiece being governed by the time delay set by the position of the latch 136. The master card is carried by spaced arcuate strips 126 to a collecting tray 31 and the workpiece passes beneath the strips 126, abuts against part of the tray 31 and falls into a collecting tray 32. A master card may be passed through the machine without printing by manual actuation of the solenoid 132 by a button (140, Fig. 1). The master cards may bear a colour code on their printing surfaces, which can be viewed by means of a mirror (143), Fig. 4a (not shown), placed beneath the master card carrier 30. Copying documents.-Solvent is supplied to the solvent-applying roller 105 from a container (111), Fig. 9 (not shown), having a ball valve, by means of a wick (108) leading from a tube (109) which extends from a well (110) beneath the container (111). The workpiece feed tray 29 and collecting tray 32 fold over to form the cover-plate (29a, 32a), Fig. 7 (not shown), for the machine.
Patent YU-46924-B (YU)
Title: Sklopna kolona
Inventor: RADMILA SECEROV-SOKOLOVIC
IPC: B01D17/02
Filed: 1988-09-05
Abstract: SKLOPNA KOLONA, naznačen time, što je sa spoljne strane na rubu poklopca (1) izvedena prirubnica (10) tako da čini nedeljiv spoj sa poklopcem (1), što je na prirubnici (10) postavljen zaptivajući prsten (11), što su na segmentima (4) izvedene na gornjim rubovima sa spoljne strane prirubnice (14) tako da čine nedeljiv spoj sa segmentima (4), što je na prirubnicama (14) postavljen zaptivajući prsten (13), što su na segmentima (4) izvedene na donjim rubovima sa spoljne strane prirubnice (10) tako da čine nedeljiv spoj sa segmentima (4), što je sa spoljne strane na gornjem delu dna (15) izvedena prirubnica (10) tako da čini nedeljiv spoj sa dnom (15), što su na bočnoj strani pri vrhu za poklopac (1) pričvršćeni dovodi (2, 2'), što su na bočnim stranama segmenata (4) i dna (15) pričvršćene cevi (5), što su na bočnim stranama u donjem delu dna (15) pričvršćeni ventilski priključak (6) i monometar (7), što su na dnu dna (15) izvedene cevi (8, 8') i priključak (9), što se izmedju poklopca (1) i dna (15) postavljaju dva ili više segmenata (4) tako da se poklopac (1) segmenti (4) i dno (15) medjusobno vezuju zavrtanjevima ili spojnim stezaljkama, što se izmedju prirubnica (10, 14) sa zaptivajućim prstenovima (11 i 13) postavlja mreža (12), što su sa donje strane mreža poklopca (1) i segmenata (4) pričvršćena plivajuća punjenja (3).
Patent RS-51051-B (RS)
Title: Hexacyclic compounds
Inventor: MURATA TAKESHI
IPC: A61P35/00
Filed: 2002-11-25
Abstract: The present invention relates to hexacyclic compound of the formula [1], wherein Z, R<SUP>3 </SUP>and R<SUP>4 </SUP>are as identified therein, and pharmaceutically acceptable salts thereof. These compounds are useful in the treatment of cell proliferative disorders.
Patent RS-50108-B (RS)
Inventor: DAO VIET DUNG
IPC: B05C1/08
Filed: 2000-12-22
Abstract: Postupak indirektnog nanošenja tankog sloja na podloge velikih površina pomoću jednog narezanog valjka (5), koj ima linije spiralnih ureza, i čija je namena da primi smesu (3) za premazivanje, koji je delimično potopljen u korito ili rezervoar (1) u kome se nalazi pomenuta smesa za premazivanje, naznačen time, što: - navedeni tanak sloj iz postupka za premazivanje ima jednaku debljinu u suvom stanju na pomenutoj podlozi izmedju 5 i 70 μm, - je širina navedene podloge 4 m, - navedena smesa (3) za premazivanje ima abrazivni karakter i što, - po izlasku iz pomenutog korita ili rezervoara (1), deo valjka (5) za nanošenje koji je izdignut, s obzirom na izjednačavanje smese za premazivanje, je u kontaktu sa valjkom (19) za izjednačavanje sa oblogom od elastomernog materijala (21), koji se okreće ili ne u istom smeru rotacije kao i valjak (5) za nanošenje i čija periferna brzina rotacije je različita od brzine valjka (5) za nanošenje. Prijava sadrži još 1 nezavisan i 6 zavisnih patentnih zahteva.
Patent ZA-826006-B (ZA)
Title: Hydrogenation process
Inventor: BRADLEY MICHAEL WILLIAM
IPC: B01J23/72
Filed: 1982-08-18
Abstract: A multi-stage hydrogenation process for hydrogenating a vaporous aldehyde to a corresponding alcohol utilising a plurality of adiabatic catalytic stages is described. Hydrogenation is allowed to occur substantially completely and adiabatically in each stage. Further vaporous aldehyde or a mixture of hydrogen and vaporous aldehyde is added to the essentially aldehyde-free mixture exiting each catalytic stage prior to entry to the next stage.
Patent ZA-828062-B (ZA)
Title: Heterocyclic compounds
Inventor: HARGREAVES RODNEY BRIAN
IPC: A61K31/54
Filed: 1982-11-03
Abstract: Heterocyclic compounds of the formula:  <IMAGE>  wherein A is a direct link, or is alkylene of 1 to 4 carbon atoms or alkenylene of 2 to 4 carbon atoms; wherein either X is -CR1R2- and Y is -O-, -S- or -NR3-, wherein R1, R2 and R3, which may be the same or different, each is hydrogen or alkyl of up to 4 carbon atoms; or X is -O-, -S- or -NH- and Y is -CR1R2- wherein R1 and R2 have the meanings stated above; and wherein Het is a 5- or 6-membered heterocyclic ring containing 1, 2 or 3 heteroatoms selected from nitrogen, oxygen or sulphur atoms, which ring may be unsubstituted or may bear one or two substituents as set out in claim 1, provided that when X is -CR1R2- and A is a direct link, Het is not unsubstituted 2-furyl; and salts thereof where appropriate; processes for their manufacture and pharmaceutical compositions containing them. The compounds possess cardiotonic and/or antihypertensive activity.
Patent ZA-836701-B (ZA)
Title: Imidazo(1,2-a)quinolines
Inventor: TULLY WILFRED ROGER
IPC: A61K31/435
Filed: 1983-09-09
Abstract: Imidazo[1,2-a]quinolines of formula I   <IMAGE>  [wherein  R1 represents a hydrogen, chlorine or bromine atom;  R2 represents a benzoyl group or a group of formula   <IMAGE> or   <IMAGE> where  R6 and R7 represent alkyl groups, R8 represents a hydrogen atom or an alkyl group and Ph represents a phenyl group;  R3 represents a hydrogen atom or an alkyl group;  R4 represents an alkoxy, hydroxy, acyloxy or alkyl group; and  R5 represents an alkyl group; provided that R1 and R3 do not both represent hydrogen atoms when R2 represents a benzoyl group and R4 represents an alkoxy group] and salts thereof have value in the treatment of anxiety and distress. Intermediates of formula V   <IMAGE> (wherein R1, R3 and R5 are as defined above and R4 represents an alkoxy, acyloxy or alkyl group) and salts thereof may be used in their preparation.
Patent ZA-845723-B (ZA)
Title: Compounds for lowering lipid levels
Inventor: KALLAI-SANFACON MARY-ANN
IPC: A61K31/215
Filed: 1984-07-24
Abstract: A method of lowering lipid levels in a mammal involves the administration of the following N-naphthoylglycine derivatives, or a therapeutically acceptable salt with an organic or inorganic base of the first three listed derivatives: N-[[5-(trifluoromethyl)-6-methoxy -1- naphthalenyl] thioxomethyl] -N- methylglycine, N-[(5-bromo-1 - napthalenyl] thioxomethyl] -N- methylglycine, N-[[6- methoxy -5- (trifluoromethylthio) -1- napthalenyl] -thioxomethyl] -N-methylglycine, and 5-hydroxy -2-[5- (trifluoromethyl) -6- methoxy -1- napthalenyl] -3- methyl- thiazolium hydroxide, inner salt. Compositions for lowering lipid levels may contain these derivatives, optionally with other hypolipidemic agents.
Patent ZA-849160-B (ZA)
Title: -2-(halogenobenzyl)-phenoxy-ethylamine derivatives
Inventor: LACOLLE JEAN-YVES
IPC: A61K31/14
Filed: 1984-11-23
Abstract: This invention is concerned with new  beta -[2-(halogenobenzyl)-phenoxy]-ethylamine derivatives of the general formula    <IMAGE>  (I)  wherein R represents a C1-C8-alkyl group having a linear or branched hydrocarbon chain, R1 and R2, which may identical or different, represent each a C1-C4-alkyl-group, and Ar represents a polychlorophenyl group of the formula    <IMAGE> (II) (in which Y1 is 4-Cl, Y2 is H or Cl, and Y3 is H or Cl, at least one of the Y2 and Y3 being Cl); and their addition salts. These new compounds are useful as pharmaceuticals.
Patent ZA-882878-B (ZA)
Title: Substituted imidazolyl-alkyl-piperazine and-diazepine derivatives
Inventor: PASCAL JEAN-CLAUDE
IPC: A61P7/06
Filed: 1988-04-22
Abstract: Substituted imidazolyl-alkyl-piperazine and diazepine derivatives of Formula A: <CHEM>  wherein:      R<1> is aryl;      R<2> is aryl, C1-4 alkyl, or hydrogen;      R<3> is C1-4 alkyl, hydroxy, or hydrogen;      R<4> is aryl;      R<5> is aryl;      m is two or three;      n is zero, one or two,  provided that when R<3> is hydroxy, n is one or two; and      q is zero, one, two, or three; and the pharmaceutically acceptable salts thereof, are useful for treating mammals having a variety of disease states, such as stroke, epilepsy or epileptic psychotic symptoms, hypertension, angina, migraine, arrhythmia, thrombosis, embolism, acute cardiac failure, irritable bowel syndrome, neurodegenerative diseases such as Alzheimer's or Huntington's chorea, diuresis, ischemia such as focal and global ischemia or cerebrovascular ischemia induced by cocaine abuse, and also for treatment of spinal injuries.
Patent ZA-905460-B (ZA)
Title: Catalyst compositions for the preparation of polymers of carbon monoxide with olefinically unsaturated compounds
Inventor: WONG PIU KWAN
IPC: C08G67/00
Filed: 1990-07-12
Abstract: Catalyst compositions comprising a Group VIII metal and a tetrakisphosphine of the general formula (R<1>R<2>P)4R<5>, wherein R<1> and R<2> represent identical or different optionally polarly substituted hydrocarbyl groups and R<5> represents a tetravalent organic group which connects the four phosphorus atoms and has such a structure that there are at least two carbon atoms between every two phosphorus atoms, and a process for the preparation of polymers of carbon monoxide with one or more olefinically unsaturated compounds using such a catalyst composition.
Patent ZA-921210-B (ZA)
Title: Method for treating systemic lupus erythematosus
Inventor: WARNER LINDA MARIE
IPC: A61K31/445
Filed: 1992-02-19
Abstract: This invention provides a method of treating systemic lupus erythematosus in a mammal in need thereof which comprises administering an effective amount of rapamycin orally, parenterally, intranasally, intrabronchially, or rectally.
Patent ZA-934473-B (ZA)
Title: Modified needle
Inventor: RIVA FRANCA
IPC: B26F1/26
Filed: 1993-06-22
Abstract: PCT No. PCT/GB93/01259 Sec. 371 Date Feb. 23, 1995 Sec. 102(e) Date Feb. 23, 1995 PCT Filed Jun. 17, 1993 PCT Pub. No. WO94/00278 PCT Pub. Date Jan. 6, 1994An apparatus for shaping perforations of sheet material which comprises a first mold structure at one side of the sheet material and a complementary mold structure at the other side of the sheet material to cooperate with the first mold structure wherein the structures are arranged to be reciprocated and are capable of meeting approximately half way through the sheet material whereby to shape the perforations between them. The apparatus can include a needle so that perforations are simultaneously formed and shaped, or it may be used to shape pre-formed perforations. If a needle is included it may be of the ultrasonic type or it may be heated, e.g. electrically heated. If a needle is used, one of the mold structures may be defined by an appropriate formation on the needle, or the structure may be separate.
Patent ZA-936006-B (ZA)
Title: Diamond temperature sensor
Inventor: JONES BARBARA LYNN
IPC: G01J5/02
Filed: 1993-08-17
Abstract: A temperature sensor comprises a body (10; 20) of insulating diamond material and a pair of spaced apart electrical contacts (12, 14; 22, 24) applied to the body. The body has a predetermined thickness between the contacts, and the contacts have a predetermined area, so that the sensor has a corresponding capacitance between the contacts which is temperature dependent The diamond body may comprise a diamond crystal, or may be a layer (20) of diamond deposited on a substrate (22) by a CVD process. In the latter case, the substrate may be a semi-conductive silicon layer, which serves as one of the contacts. The other contact (24) may be a metallic contact, or may comprise a layer of doped amorphous semi-conductive material. The sensor is sensitive to ionising radiation as well as to changes in temperature, and is suitable for use in a temperature compensated radiation measuring apparatus.
Patent ZA-937950-B (ZA)
Title: Process for the preparation of lubricating base oils
Inventor: GUICHARD PHILIPPE
IPC: B01J23/40
Filed: 1993-10-26
Abstract: A process for the preparation of a lubricating base oil including contacting a hydrocarbon feed with a catalyst in the presence of hydrogen, which catalyst includes a hydrogenation component supported on an amorphous silica-alumina carrier having a macroporosity in the range of from 5% vol to 50% vol. The hydrocarbon feed is most preferably a slack wax or a synthetic wax. The preferred catalyst for use in the process includes a combination of one or more of the metals cobalt, iron, and nickel, and one or more of the metals chromium, molybdenum, and tungsten on an amorphous silica-alumina carrier having a macroporosity in the range of from 5% vol to 50% vol.
Patent ZA-941812-B (ZA)
Title: Isolated nucleic acid sequence coding for a tumor rejection antigen precursor processed to at least one tumor rejection antigen presented by HLA-A2
Inventor: BRICHARD VINCENT
IPC: G01N33/574
Filed: 1994-03-15
Abstract: The invention relates to nucleic acid molecules coding for a tumor rejection antigen precursor. Specifically, the tumor rejection antigen precursor, or "TRAP", is processed into at least one tumor rejection antigen, which is presented by HLA-A2 molecules. Ramifications of the discovery are also set forth.
Patent ZA-967032-B (ZA)
Title: Pharmaceutical compositions
Inventor: JOHNSON EDWARD STEWART
IPC: A61K31/485
Filed: 1996-08-19
Abstract: In one embodiment, this invention relates to a pharmaceutical composition for oral administration consisting essentially of a gelatin at a concentration up to 5% by weight as a carrier, a solvent, and, as an active ingredient, a dopamine agonist. Alternatively, the invention relates to a composition that takes the form of a solid, unitary fast-dispersing dosage form comprised of a network of an active ingredient after and a water-soluble or water dispersible matrix forming agent or carrier which is inert towards the active ingredient after subliming solvent from the composition in the solid state. The dosage is designed to completely disintegrate within 1 to 30 seconds of being placed in the oral cavity. Compositions which further comprise an anti-emetic and/or an opioid antagonist are also provided herein.
Patent ZA-971279-B (ZA)
Title: Use of 5ht4 receptor antagonists for overcoming gastrointestinal effects of serotonin reuptake inhinitors
Inventor: MEULEMANS ANN LOUISE GABRIELLE
IPC: A61K31/454
Filed: 1997-02-14
Abstract: PCT No. PCT/EP97/00586 Sec. 371 Date Aug. 11, 1998 Sec. 102(e) Date Aug. 11, 1998 PCT Filed Feb. 7, 1997 PCT Pub. No. WO97/29739 PCT Pub. Date Aug. 21, 1997The present invention concerns the use of receptor antagonists of the 5HT4 receptor for avoiding, alleviating, suppressing or overcoming the gastrointestinal side-effects of serotonin reuptake inhibitors. The present invention also concerns pharmaceutical formulations comprising 5HT4-receptor antagonists for alleviating, suppressing or overcoming the gastrointestinal side-effects of serotonin reuptake inhibitors, as well as pharmaceutical compositions comprising 5HT4 receptor antagonists and serotonin reuptake inhibitors.