baber/WOPTO huggingface dataset:
Patent CA-2835261-C (CA)
Inventor: CRAMP SUSAN MARY
IPC: A61K31/335
Filed: 2012-05-07
Granted: 2019-06-04
Abstract: The invention provides tricyclic compounds and their use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of making various tricyclic compounds are provided. The compounds are contemplated to have activity against methionyl aminopeptidase 2.
Patent CA-2835357-C (CA)
Title: Methode, systeme et appareil pour fournir des notifications pour differents espaces de travail
Inventor: GERIS RYAN ALEXANDER
IPC: G06F3/00
Filed: 2013-11-27
Granted: 2022-11-15
Abstract: Il est décrit une méthode, un système et un appareil servant à fournir des notifications à différents espaces de travail. L'appareil en question comprend un processeur, une mémoire et un dispositif de notification. Le processeur peut gérer un premier et un deuxième espace de travail qui se distinguent comme suit : l'association des données stockées en mémoire avec soit le premier espace de travail, soit le deuxième espace de travail; l'association des comptes avec soit le premier espace de travail, soit le deuxième espace de travail. Le processeur peut également contrôler l'appareil de notification lorsque le premier espace de travail constitue l'espace de travail actuel, et ce, afin de présenter de premières notifications associées au premier espace de travail seulement, sans présenter de deuxièmes notifications associées au deuxième espace de travail.
Patent CA-2839142-C (CA)
Inventor: PLOGER FRANK
IPC: A61F13/00
Filed: 2012-06-21
Granted: 2019-04-16
Abstract: The present invention is directed to novel non-woven fabrics containing growth and differentiation factor proteins. Said fabrics are specifically designed to accelerate tissue regeneration and wound healing processes of mammalian tissues. Furthermore, the invention provides wound dressings, pads or implants comprising the novel non-woven fabrics.
Patent CA-2844491-C (CA)
Title: Mounting face system
Inventor: WOLTERS LAURENS G J
IPC: B65G23/08
Filed: 2012-08-13
Granted: 2019-10-22
Abstract: A motorized drum has a drum shell having an inner periphery and a central axis, with a motor and a reducer disposed therewithin for delivering rotary power to the drum shell at a determined region thereof. A mounting face system has a mounting face arrangement that receives components to be attached to alter the length of the motorized drum. The mounting face arrangement is disposed at an end of the motorized drum distal from the region where the reducer delivers power to the drum shell. The mounting face arrangement limits the flexure of the attachable components such that the deflection curve is continuous to reduce stress concentration.
Patent CA-2844937-C (CA)
Inventor: WALTON J RODNEY
IPC: H04B7/01
Filed: 2007-05-22
Granted: 2015-02-10
Abstract: Techniques for performing phase correction for wireless communication are described. Received pilot symbols and received data symbols may be obtained from an orthogonal frequency division multiplexing (OFDM) and/or multiple-input multiple-output (MIMO) transmission. First phase information is obtained based upon the received pilot symbols. Second phase information is obtained based upon the received data symbols. The phase of the received data symbols is corrected based upon the first and second phase information (directly and/or indirectly). For example, the phase of the received data symbols may be corrected based upon the first phase information, detection may be performed on the phase corrected data symbols to obtain estimated data symbols, the second phase information may be obtained based upon the estimated data symbols, and the phase of the estimated data symbols may be corrected based upon the second phase information. The phase correction may also be performed in other manners.
Patent CA-2846369-C (CA)
Inventor: NAZARE MARC
IPC: A61P19/02
Filed: 2011-09-19
Granted: 2018-11-13
Abstract: The present invention relates to N-[4-(1H-pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]- sulfonamides of the formula I, wherein Ar, R1, R2 and n have the meanings indicated in the claims. The compounds of the formula I are valuable pharmacologically active compounds which modulate protein kinase activity, specifically the activity of serum and glucocorticoid regulated kinase (SGK), in particular of serum and glucocorticoid regulated kinase isoform 1 (SGK-1, SGK1), and are suitable for the treatment of diseases in which SGK activity is inappropriate, for example degenerative joint disorders or inflammatory processes such as osteoarthritis or rheumatism. The invention furthermore relates to processes for the preparation of the compounds of the formula I, their use as pharmaceuticals, and pharmaceutical compositions comprising them.
Patent CA-2848016-C (CA)
Inventor: OLSEN JOHN
IPC: G08C17/02
Filed: 2005-01-10
Granted: 2019-02-19
Abstract: The invention is directed to a data collection and evaluation system that includes a telematics device for collecting, time-stamping, and storing vehicle sensor data. Example of the type of data collected include door data, ignition data, speed data, global positioning data, and diagnostic and trouble code data. The system further includes an external data acquisition device, such as a mainframe computer system or a hand-held computing device like an iPAQ. The external data acquisition device is configured to communicate with the telematics device over a wireless network, which enables the telematics device to transmit the time-stamped data to the external data acquisition device and receive information and instructions from the external data acquisition device. The ability of the system to automatically collect and transfer data and communication with an external data acquisition device allows for the automation of fleet management processes, vehicle maintenance and repair processes, and certain security features.
Patent CA-2849105-C (CA)
Inventor: COHEN MATTHEW
IPC: A61F2/02
Filed: 2012-10-01
Granted: 2019-11-05
Abstract: A hernia repair device includes a mesh configured to extend across a tissue defect and a plurality of filaments coupled to the mesh. The filaments are coupled to the mesh in proximity of an outer periphery thereof and extend from a central portion of the mesh. Each filament includes a plurality of barbs disposed along at least a portion of the length thereof. Each filament further includes a needle disposed at a free end thereof.
Patent CA-2851777-C (CA)
Inventor: EVANS DAVID A
IPC: B22F7/08
Filed: 2012-10-02
Granted: 2018-08-14
Abstract: A method of making a sintered article (4) in which a solid object (3') is embedded includes forming a green body (1) of compressed particles with the solid body (3) is partially embedded. The green body includes an opening (6) across which the solid body extends. The green body is sintered to form a sintered body and the opening permits deformation of the solid body in response to stress applied during the sintering process. A sintered article (4) in which a solid body (3') is at least partially embedded includes an opening (6). The solid body extends across the opening so that the solid body can deform within the opening. The opening in the solid body prevents distortion of the sintered body from a planar configuration during sintering, even when the green body is relatively thin.
Patent CA-2863230-C (CA)
Inventor: JACKSON GREGORY R
IPC: A61B/
Filed: 2004-09-03
Granted: 2016-07-19
Abstract: The present method describes a new method for the measurement of dark adaptation. The dark adaptation status of subjects may then be used to identify those subjects who are at risk of developing and/or who are currently suffering from a variety of disease states having their clinical manifestations in impaired dark adaptation. The disease states include, but are not limited to, age related macular degeneration, vitamin A deficiency, Sorsby's Fundus Dystrophy, late autosomal dominant retinal degeneration, retinal impairment related to diabetes and diabetic retinopathy. An apparatus for administering the test method described is also provided.
Patent CA-2863759-C (CA)
Inventor: READER JOHN CHARLES
IPC: A61P35/00
Filed: 2013-02-04
Granted: 2020-04-14
Abstract: La présente invention concerne un composé de formule (1) utile comme modulateur de l'activité des kinases Aurora et des kinases FLT3 : et ses sels ; où R1 est un groupe hydrogène ou alkyle en C1-2 ; et R2, R3 et R4 sont identiques ou différents et chacun est choisi parmi un groupe hydrogène, alkyle en C1-2, fluor, chlore, alcoxy en C1-2 et trifluorométhyle, à condition que pas plus de deux R parmi R2, R3 et R4 soient autres qu'un groupe hydrogène. L'invention concerne également des compositions pharmaceutiques contenant les composés et leur utilisation en médicine, en particulier dans le traitement du cancer.
Patent CA-2877794-C (CA)
Inventor: FROYMAN ROBRECHT
IPC: A61P31/04
Filed: 2013-06-25
Granted: 2020-08-04
Abstract: The present invention relates to a pharmaceutical composition and methods of treating and/or preventing mastitis in non-human mammals. More particularly, the present invention relates to the treatment of mastitis in cows. The pharmaceutical composition comprises a mixture of a phosphonic acid and at least one antimicrobial wherein the phosphonic acid is selected from the group consisting of fosfomycin, alafosfalin, and a pharmaceutically acceptable salt thereof, and wherein the antimicrobial is selected from the group consisting of enrofloxacin, moxifloxacin, pradofloxacin, .beta.-lactams, macrolide-streptogramin-lincosamides, and a pharmaceutically acceptable salt thereof.
Patent CA-2878564-C (CA)
Title: Diazepinone derivatives useful for the treatment of fragile x syndrome, parkinsons or reflux disease
Inventor: BEHNKE DIRK
IPC: A61P1/04
Filed: 2013-08-21
Granted: 2021-08-03
Abstract: (see formula I) The invention relates to compound of the formula (I) or a salt thereof, wherein the substituents are as defined in the specification; to its preparation, to its use as medicament and to medicaments comprising it. The compounds of the invention are mGluR5 antagonists and are therefore potentially useful in the treatment of a wide range of disorders, such as fragile X  syndrome, L-dopa induced dyskinesias in Parkinson's Disease and Gastro-Esophageal Reflux Disease.
Patent CA-2887053-C (CA)
Inventor: SHANKAR RAVI B
IPC: C07F9/40
Filed: 2013-10-08
Granted: 2020-11-17
Abstract: L'invention concerne un sel de carboxylate d'aluminium ayant la formule A1[OCO(CH2)nP(O)( OR1)(OR2)]3 dans laquelle R1 et R2 représentent des groupes hydrocarbyle qui peuvent être éventuellement joints et n est indépendamment un nombre entier compris entre un et quatre, qui est utile pour former un article manufacturé comprenant un polymère composé avec le sel de carboxylate d'aluminium pour former un article en polymère ignifugé.
Patent CA-2889108-C (CA)
Inventor: OLSON WILLIAM A
IPC: A61B17/32
Filed: 2013-10-09
Granted: 2020-12-08
Abstract: In one embodiment, a surgical instrument comprises an articulable harmonic waveguide. The articulable harmonic waveguide comprises a first drive section comprising a proximal end and a distal end. The proximal end of the first drive section may be configured to connect to an ultrasonic transducer. The articulable harmonic waveguide further comprises a first flexible waveguide coupled to the distal end of the first drive section. An end effector extends distally from the first flexible waveguide. The surgical instrument further comprises an articulation actuator to flex the first flexible waveguide.
Patent CA-2896084-C (CA)
Inventor: CUSHINGHAM STEVEN JOHN
IPC: F41H1/02
Filed: 2013-12-23
Granted: 2019-10-22
Abstract: La présente invention concerne des tissus réalisés avec des mélanges de fibres et des réalisations étudiées pour améliorer la protection balistique de même que le confort et/ou l'aptitude à la teinture/l'aptitude à l'impression de ces tissus.
Patent CA-2898860-C (CA)
Title: Predictive neurodevelopment therapy for oral feeding
Inventor: ARON KENNETH
IPC: A61B5/00
Filed: 2014-01-21
Granted: 2023-03-21
Abstract: The present disclosure relates to a therapeutic system and methods of using the therapeutic system. In particular, the present disclosure relates to a system for improving an oral feeding ability of a patient including an assessment device to contact a patient and collect data related to an oral feeding ability of the patient, a computing device containing a processor to execute an assessment and therapy application, and the assessment and therapy application to receive the data related to the oral feeding ability, predict one or more areas of neurological muscle activity that need further development, and develop a neurological therapy treatment for improving the one or more areas of neurological muscle activity that need further development.
Patent CA-2903095-C (CA)
Inventor: LIU XIAOHAI
IPC: C07H19/20
Filed: 2013-03-15
Granted: 2018-02-13
Abstract: Some embodiments described herein relate to modified nucleotide and nucleoside molecules with novel 3'-hydroxy protecting groups. Said 3'-hydroxy protecting groups form a structure -O-C(R)2N3 covalently attached to the 3'-carbon atom wherein R is as defined n the claims. Also provided herein are methods to prepare such modified nucleotide and nucleoside molecules and sequencing by synthesis processes using such modified nucleotide and nucleoside molecules.
Patent CA-2903146-C (CA)
Inventor: SANKARAN SETHURAMAN
IPC: A61B6/00
Filed: 2014-02-27
Granted: 2017-09-05
Abstract: Des modes de réalisation comprennent des systèmes et des procédés pour déterminer une information cardiovasculaire pour un patient. Un procédé comprend la réception de données spécifiques du patient concernant la géométrie du système vasculaire du patient; la création d'un modèle anatomique représentant au moins une partie du système vasculaire du patient basée sur les données spécifiques du patient; et la création d'un modèle computationnel d'une caractéristique du débit sanguin basée sur le modèle anatomique. Le procédé comprend également l'identification d'un ou plusieurs éléments parmi un paramètre incertain, une variable clinique incertaine et une géométrie incertaine; la modification d'un modèle de probabilité basée sur un ou plusieurs éléments parmi le paramètre incertain, la variable clinique incertaine ou la géométrie incertaine identifié; la détermination d'une caractéristique du débit sanguin dans le système vasculaire du patient basée sur le modèle anatomique et le modèle computationnel de la caractéristique du débit sanguin du système vasculaire du patient; et le calcul, basé sur le modèle de probabilité et la caractéristique du débit sanguin déterminée, d'une sensibilité de la réserve de débit fractionnaire déterminé à un ou plusieurs parmi le paramètre incertain, la variable clinique incertaine ou la géométrie incertaine identifié.
Patent CA-2909272-C (CA)
Inventor: BOIRA BONHORA JORDI
IPC: B65B55/12
Filed: 2015-10-15
Granted: 2021-02-02
Abstract: Method for the aseptic filling of a bag with a pharmaceutical product or liquid which comprises the following steps: a) a first step in which the cap is inserted in the inlet of the bag; b) a second step in which said cap is raised and the pharmaceutical product or liquid concerned is introduced; c) a third step in which the cap is re-inserted in the inlet of the bag; and d) a fourth step in which the cap and the inlet of the bag are welded.
Patent CA-2912389-C (CA)
Title: Methods and compositions for reducing immunosupression by tumor cells
Inventor: WUCHERPFENNIG KAI W
IPC: C12N15/113
Filed: 2014-06-10
Granted: 2020-01-28
Abstract: The present disclosure provides, in part, methods of discovering immunotherapy targets in vivo, therapeutic compositions (e.g., shRNA, immunoresponsive cells expressing shRNA and/or a chimeric antigen receptors (CAR)), and methods of use thereof.
Patent CA-2912748-C (CA)
Title: Roofing panel with interlocking clipping system
Inventor: ANDERSON ERIC R
IPC: E04D1/12
Filed: 2015-11-23
Granted: 2022-04-12
Abstract: Metal roofing panels have a forward edge portion with a downwardly extending skirt and return flange and a rear edge or headlap portion with an upwardly open channel and a locking tab extending over a portion of the upwardly open channel. A method of installing the roofing panels includes nailing a lower course of panels in end-to-end overlapping relationship to a roof deck. The forward edge portions of panels in the next higher course of panels are then pressed downwardly into the upwardly open channels of the lower course panels. The return flanges of the upper course panels snap beneath the locking tabs of the upwardly open channels thus locking the panels together and forming a watertight connection between courses of panels.
Patent CA-2914871-C (CA)
Title: Method and system for producing methanol using partial oxidation
Inventor: CHAKRAVARTI SHRIKAR
IPC: C07C29/151
Filed: 2015-12-11
Granted: 2021-01-12
Abstract: The present invention relates to a method and system for producing methanol incorporating partial oxidation or autothermal reforming of a hydrocarbon feed stream. The method comprises: (i) producing a first stream of synthesis gas having a module greater than 2.0, in a steam methane reformer (SMR) or in a SMR followed by an autothermal reformer, by reforming a first hydrocarbon feed stream and steam in the presence of a catalyst; (ii) producing a second stream of synthesis gas having a module less than that of the first stream of synthesis gas, by partial oxidation or autothermal reforming of a second hydrocarbon feed stream; (iii) combining the first stream of synthesis gas and the second stream of synthesis gas to form a combined synthesis gas stream; and (iv) synthesizing the combined synthesis gas product stream in a methanol synthesis reactor into a product composition comprising methanol.
Patent CA-2916127-C (CA)
Title: Trousse de fabrication de chapeau et methode de conditionnement associee
Inventor: LOMBARDI DOMINICK
IPC: D04B15/00
Filed: 2015-12-23
Granted: 2018-08-21
Abstract: Trousse permet de créer un vêtement tricoté, comme un chapeau. La trousse comprend une longueur de fil, un dessus, un stabilisateur et facultativement des instructions expliquant comment créer le vêtement à partir du fil, du dessus et du stabilisateur. Une méthode demballage de la trousse est également présentée.
Patent CA-2920001-C (CA)
Inventor: ELPHICK DAVID
IPC: A63C5/00
Filed: 2014-08-01
Granted: 2022-11-29
Abstract: La présente invention concerne un ensemble de snowboard qui comprend un plateau soutenu au-dessus d'une paire de lames longitudinalement espacées. Le plateau a une surface supérieure pour soutenir un utilisateur sur celui-ci et chaque lame a une surface inférieure pour entrer en contact avec de la glace ou de la neige sur laquelle l'ensemble de snowboard est utilisé. Le plateau est soutenu au-dessus des lames par des supports qui sont intercalés entre chaque lame et le plateau. Le plateau est rigide en torsion entre les supports de sorte que, en utilisation, les forces de transfert de poids induites par l'utilisateur puissent être transférées du plateau par l'intermédiaire d'un ou des deux supports et dans une ou les deux lames afin d'orienter l'ensemble. Les supports peuvent être des ensembles de chariot qui permettent aux lames de se déplacer indépendamment par rapport au plateau.
Patent CA-2921155-C (CA)
Title: Procede et analyse de charge pour plusieurs outils decentres
Inventor: SAMUEL ROBELLO
IPC: G01L5/04
Filed: 2013-09-25
Granted: 2018-07-17
Abstract: Divers modes de réalisation comprennent un appareil et des procédés permettant d'effectuer une analyse de charge pour plusieurs outils décentrés. Des constituants décentrés d'une rame de complétion subissent des forces additionnelles de trainée et de fond de trou dues au contact avec des parois de tubage et de colonne perdue qui peuvent provoquer des charges et des contraintes excessives conduisant à des pannes. Des systèmes et des techniques sont fournis pour analyser de telles situations. D'autres appareils, systèmes et procédés sont également décrits.
Patent CA-2921342-C (CA)
Inventor: LARSEN SCOTT P
IPC: A61B17/82
Filed: 2014-08-12
Granted: 2022-07-05
Abstract: A method and apparatus including at least one suture anchor configured to be implanted into bone and at least one suture assembly configured to extend from the suture anchor and about at least a portion of a fibula when the suture anchor is implanted in a tibia on either side of a fibular notch of the tibia. The suture assembly is selectively adjustable from a non-tensioned condition to a tensioned condition to stabilize and reduce the fibula relative to the tibia.
Patent CA-2927532-C (CA)
Title: Traitement synchronise de donnees par ressources de calcul en reseau
Inventor: KATSUYAMA BRADLEY
IPC: G06Q40/04
Filed: 2010-06-08
Granted: 2016-08-09
Abstract: On propose des systèmes (100, 1000), des procédés et une programmation interprétable par une machine ou dautres produits dinstruction pour la gestion du traitement de données par de multiples ressources informatiques en réseau (106, 1106). Linvention concerne en particulier la synchronisation des demandes associées pour le traitement des données à laide de ressources en réseau distribuées.
Patent CA-2930290-C (CA)
Inventor: WARNER JOHN C
IPC: C07F15/02
Filed: 2014-11-10
Granted: 2023-02-28
Abstract: In one embodiment, the present application discloses compounds that are selective neuroactive agents for the treatment of diseases of the central nervous system (CNS). In one aspect, the neuroactive agents are NCDs of metal chelates, including complexes of iron, copper or zinc.
Patent CA-2932969-C (CA)
Title: Product comprising red clover extract and methods for producing the same
Inventor: JENSEN MICHAEL MOHR
IPC: A61P35/00
Filed: 2013-12-12
Granted: 2021-11-23
Abstract: The invention relates to a composition comprising isoflavones from red clover. The red clover extract has been fermented to obtain a composition comprising aglycone isoflavones. The fermentation is preferably performed by a lactic acid bacteria or fermented dandelion extract.
Patent CA-2933538-C (CA)
Inventor: JANOT CYRIL
IPC: G07F7/08
Filed: 2016-06-16
Granted: 2023-08-29
Abstract: Il est décrit un terminal électronique fixe (100) qui comprend au moins un emplacement (10) conçu pour recevoir de façon réversible un système électronique de gestion de lautonomie du terminal.
Patent CA-2934046-C (CA)
Inventor: NGUYEN MINH-TUAN
IPC: E21B43/26
Filed: 2014-12-18
Granted: 2018-08-07
Abstract: A system for fracturing a hydrocarbon bearing formation includes a valve including a tubular housing having a bore therethrough and one or more flow ports formed through a wall thereof. One or more locator tags are embedded in the housing, and a sleeve is disposed in the housing and movable relative thereto between an open and a closed position. The system also includes a shifting tool comprising a shifter movable between an extended position and a retracted position and operable to engage the valve sleeve. The shifting tool includes a lock that keeps the shifter extended in the locked position and allows the shifter to retract in the unlocked position. The shifting tool also includes an antenna for detecting the locator tags, and an electronics package in communication with the antenna and the actuator for operating the actuator in response to detection of the locator tags.
Patent CA-2940666-C (CA)
Title: Inhibiteurs de tyk2 et leurs utilisations
Inventor: MASSE CRAIG E
IPC: A61K31/437
Filed: 2015-02-27
Granted: 2022-08-23
Abstract: La présente invention concerne des composés, des compositions de ceux-ci, et des procédés d'utilisation de ceux-ci pour l'inhibition de TYK2, et pour le traitement de troubles médiés par TYK2.