baber/WOPTO huggingface dataset:
Patent CA-2318355-A1 (CA)
Title: Chimeric proteins for the treatment of diabetes
Inventor: MATIS LOUIS A
IPC: C07K14/62
Filed: 1998-12-23
Abstract: Novel chimeric fusion proteins comprising immunodominant epitopes of GAD and insulin are provided. Also provided are immunomodulatory methods for the use of such proteins for both the prevention and treatment of Type 1 diabetes mellitus. The chimeric fusion proteins of the invention are useful in predicting risk of onset of Type 1 diabetes, determining prognosis of Type 1 diabetes patients early in disease progression, and in evaluating patients for suitability as recipients of transplants of pancreatic cells or tissues. The administration of the proteins of the invention in accordance with the immunomodulatory methods of the invention results in beneficial effects on disease development and severity in patients suffering from or predicted to be at risk of developing Type 1 diabetes, as well as on the outcome of transplants of pancreatic cells or tissues in Type 1 diabetes patients.
Patent CA-2320574-A1 (CA)
Title: Radar for space-borne use
Inventor: WHEADON NIGEL SPENCER
IPC: G01S7/02
Filed: 2000-09-22
Abstract: Faraday Rotation causes rotation of the plane of polarisation of plane polarised radiation emitted by a radar e.g. a synthetic aperture radar and, if returns polarised in orthogonal planes are measured at the synthetic aperture radar in order to determine polarimetric characteristics of the ground, which could show up features of the ground such as crop patterns, tho measurements made at the SAR are contaminated by the Faraday Rotation. In the invention, the transmitted plane polarised beam is pre-rotated in transmitter 9, the radar returns in receiver 13 are mathematically adjusted in signal formatting 14, 15 to compensate for just the pre-rotated angle, to produce data streams on downlink uncontaminated by the Faraday Rotation. The Faraday Rotation may be estimated by external means 11, 12, or by performing correlation 10 of the orthogonally polarised radar returns to establish a minimum, while the pre-rotation angle and mathematical correction of the returns arc being iteratively adjusted, at which Faraday Rotation is assumed to be compensated.
Patent CA-2320760-A1 (CA)
Title: Flat lighting device, and an operating method
Inventor: HITZSCHKE LOTHAR
IPC: F21Y103/37
Filed: 1999-11-11
Abstract: The invention relates to a flat lighting device (1) comprising a light-conducting plate (2) and at least two electrical light sources (3, 4) which can be used to couple light into a light-conducting plate (2). A first light source (3) is adjacent to the light-conducting plate (2) and a second light source (4) is arranged behind the first light source (3), as seen from the light-conducting plate (2), in such a way that the light which is emitted from the second light source (4) during operation can enter at least partially the light-conducting plate (2) by traversing the first light source (3). In dimming operation, the first light source (3) which is closest to the light-conducting plate (2) is switched off and softens the light flux which is to be coupled from the second light source (4) into the light-conducting plate (2).  In this way, extreme dimming is possible without the light source changing its electrical or luminous characteristics.
Patent CA-2323326-A1 (CA)
Inventor: CHU JINCHI
IPC: H04L29/02
Filed: 2000-10-16
Abstract: A communications network includes packet-based networks (12, 21) that are coupled to various network elements. A method and apparatus is provided to implement telephony services in the communications network. The architecture for providing the telephony services may include several layers, including a network elements layer (104), an interface layer (102), and a services/application layer (100). The services/application layer (100) is decoupled from the specific implementations of the network elements layer (104) so that a more flexible and convenient mechanism is provided to create telephony services. The telephony services may be implemented in software modules written in one of several possible languages, such as a telephony scripting language (TSL) or other language. The interface layer (102) includes various components, including translation components (110) to interpret and execute the modules that are in the services/application layer (100), communications components (112) to provide mechanisms to send commands to the network elements layer (104) to perform specified telephony services, and representation components (114) that describe the functions, tasks, and other details associated with network elements.
Patent CA-2325744-A1 (CA)
Inventor: WARING ALAN J
IPC: A61K9/127
Filed: 1999-02-04
Abstract: Described herein are liposome complexes and the individual components thereof for intracellular and/or intranuclear delivery of substances. Methods of use of the provided liposome complexes and components are also described. Generally, the liposome complexes described herein include a non-cationic lipid, a fusogenic peptide and a substance to be delivered to the cell and/or nucleus. In some of the liposome complexes described herein, the fusogenic peptide does not contain multiple positive charges at neutral pH and above. In these liposome complexes, two additional components are used in assembling the liposome complex with DNA.
Patent CA-2325860-A1 (CA)
Inventor: SHAI SHAFRIRA
IPC: G01N21/64
Filed: 1999-03-16
Abstract: The present invention relates to a system to analyse general diagnostic factors in cells and body fluids using a flow cytometer, and in particular to a system featuring a number of different fertility tests, in a simple, expedited format, in order to investigate factors affecting fertility, preferably in a semi or fully automated manner. Specifically, a preparative method has been developed to increase the success of in vitro fertilisation (I.V.F.) and intrauterine insemination (I.U.I.) in cases of immunoinfertility by removing sperm-bound antibodies from sperm cells. A special device has been designed to collect only motile sperm cells from semen samples. Thus, this invention provides improved methods for general diagnostic testing and infertility screening and enables gynecologists to obtain information from an infertile couple in a preliminary test, which until now has been time consuming and only possible to run in sophisticated laboratories.
Patent CA-2329428-A1 (CA)
Inventor: GLASER LAWRENCE F
IPC: A23L1/164
Filed: 1999-04-21
Abstract: A consumer cereal product including at least first (54) and second portions (56), the first portion (54) having a specific gravity less than a liquid, such as milk, so that it floats in the liquid, and the second portion (56) having a specific gravity greater than that liquid so that it sinks therein.  The cereal may also be coated with a soluble coating (52). As the coating dissolves, the cereal may sink, float or even rotate in the liquid. In each case, the cereal is colored, textured, shaped, sized, or otherwise differentiated to provide entertainment to a consumer of the product. The various embodiments can be combined as desired to achieve a cereal product that provides amusement and entertainment to consumers thereof.
Patent CA-2329762-A1 (CA)
Title: Pharmaceutical imidazole combination for locally treating vulvovaginitis and vaginosis
Inventor: VERDIER STEPHANIE
IPC: A61K31/415
Filed: 1999-04-23
Abstract: The invention concerns a pharmaceutical composition comprising a combination of at least two imidazole derivatives having reinforcing synergy against germs which cause infectious vulvovaginitis and vaginosis and selected from the group comprising metronidazole, econazole, miconazole, clotrimazole, terconazole, bifonazole, cloconazole, isoconazole, oxiconazole, sulconazole, tioconazole and their salts, preferably metronidazole combined with econazole. The composition is advantageously in galenic form of a hard or soft capsule having an solid hard or soft outer envelope containing gelatine, enclosing an internal non-aqueous lipophilic liquid or semi-liquid phase wherein the imidazole derivatives are suspended in a lipophilic agent, a water-dispersible agent and a bioadhesive agent.
Patent CA-2330737-A1 (CA)
Title: Flow machine for a fluid with a radial sealing gap between stator parts and a rotor
Inventor: PESEK TOMAS
IPC: F04D29/16
Filed: 2001-01-10
Abstract: Shown with the invention are self-supporting wear rings (1a, 1b) for flow machines with a fluid, which are arranged at a radial sealing gap (18) to a rotor (9), and of which the outer jacket surface (3) is provided with a wear surface (2). The wear rings (1a, 1b), which are fixed in the axial direction, consist of a material with lower thermal expansion coefficients than their support and lie hollowly on their inner jacket surface, with a first conical holder surface (8) encountering with the apex of its cone a second holder surface (8"), which is designed as straight shoulder, in the plane of the latter (19) on the axis of rotation or encountering a second holder surface, which is designed as a conical holder surface (8'), at its cone apex on the axis of rotation (20).
Patent CA-2331363-A1 (CA)
Inventor: BRENNAN WILLIAM J JR
IPC: H04B1/7156
Filed: 2000-03-04
Abstract: A frequency hopping spread spectrum wireless transmission system includes a transmitter (10) and a receiver (38) system. The transmitter (10) is configured to transmit radio frequency data signals in sequential time periods on respective transmit channels according to a predetermined sequence. The data signal in each time period includes information relating the data signal to its position within the predetermined sequence. The receiver (38) system is configured to monitor a plurality of receive channels over a frequency range that includes the transmit channels and to receive the data signals on the receive channels. The receiver (38) system is also configured to determine, upon reception of a first data signal on a first receive channel, a next receive channel based on the first receive channel so that the next receive channel differs from the first receive channel an amount equal to the interval between the data signals position and the next position in the sequence, and to monitor the next receive channel for a next data signal.
Patent CA-2333638-A1 (CA)
Title: Polyolefin-tie material free barrier carton with polyethylene terephthalate product contact layer
Inventor: GIBBONS CHARLES E
IPC: B32B27/10
Filed: 1999-05-28
Abstract: A laminate structure for producing paperboard or polymer containers and blow molded bottles containing a barrier structure of layer(s) of polyethylene terephthalate (14) and a layer of ethylene vinyl alcohol copolymer (12), wherein no polyolefin based tie layers are used in the structure. The container or bottle produced therefrom is recyclable and has dimensional stability.
Patent CA-2333725-A1 (CA)
Title: Exemplar workflow used in the design and deployment of a workflow for multi-enterprise collaboration
Inventor: NOTANI RANJIT N
IPC: G06Q10/00
Filed: 1999-06-03
Abstract: An exemplar workflow is disclosed for use in the design and deployment of a workflow for multi-enterprise collaboration. The computer implemented proces s involves allowing a workflow design to include at least one exemplar workflo w. The exemplar workflow is associated with an exemplar node allowing at least one activity to be parameterized over a plurality of nodes within a node group. The process then involves instantiating the workflow such that the at  least one exemplar workflow is instantiated as a plurality of activities eac h associated with a specific node in the node group. The workflow is deployed by distributing the activities over the nodes in the node group to provide mult i- enterprise collaboration.
Patent CA-2335475-A1 (CA)
Inventor: MUNTANE CONDEMINES MIQUEL
IPC: H04B1/38
Filed: 1999-06-21
Abstract: The mobile telephone is divided into two groups of elements: a first radiation emitter-receiver group (6) comprised of the receiver, the emitter, the antenna (2) and a telescopically extensible support rod for the user; and a second personal communication group (7) comprised of the loud speaker (3), the microphone (4), the keyboard (12), the screen (17) and the body (5); both groups communicate either with or without cable. During the communication, the emitter-receiver group is separated from the personal communication group (7) so that the power density of the radiation arriving to the personal communication group and therefore to the user can be lower than 0.1 microW/cm2. In the absence of communication, the emitter-receiver group is inserted nested into a housing provided to this effect in the body. It can be used both for individual and collective applications.
Patent CA-2336781-A1 (CA)
Title: Hypericin and hypericum extract: specific t-type calcium channel blocker, and their use as t-type calcium channel targeted therapeutics
Inventor: SHAN JACQUELINE J
IPC: A61P25/28
Filed: 1999-07-09
Abstract: Hypericin has been shown to specifically inhibit T-type calcium channel activity. Hypericum extract containing hypericin also inhibits T-type calciu m channel activity. Moreover, other chemicals in Hypericum extract showed a synergistic effect to hypericin. In view of this, hypericin or hypericin- containing Hypericum extract can be used as T-channel blockers. Hypericum extract, extract of other species of the Hypericum genus, extract of other plants containing hypericin, hypericin derivatives, hypericin analogs, such as pseudohypericin, and other Hypericum extract constituents can be used as therapeutics targeted at T-type calcium channels for treatment of diseases associated with T-channel abnormality. Methods for administering hypericin a nd Hypericum extract are disclosed.
Patent CA-2336968-A1 (CA)
Title: Quinoline derivatives
Inventor: HEDLUND GUNNAR
IPC: C07D215/56
Filed: 1999-07-14
Abstract: The invention is related to compounds of general formula (I), wherein R is methyl, ethyl, n-propyl, iso-propyl, n-butyl or allyl; R' is methyl, methoxy, fluoro, chloro, bromo, trifluoromethyl, or OCH x F y, wherein x = O - 2, y = 1 - 3 with the proviso that x + y = 3; R" is hydrogen, fluoro or chloro; with the proviso that R" is fluoro or chloro only when R' is fluoro; R4 is hydrogen or pharmaceutically acceptable inorganic or organic cations; R5 is ethyl, n-propyl, iso-propyl, methoxy, ethoxy, chloro, bromo, trifluoromethyl, OCH x F y, or OCH2CH x F y wherein x = 0 - 2, y = 1 - 3 with the proviso that x + y = 3; R6 is hydrogen; or R5, and R6 taken together are methylenedioxy; and any tautomer thereof. The invention also relates to pharmaceutical compositions containing a compound of general formula (I) together with a pharmaceutically acceptable carrier. Included are also processes for the preparation of the compounds of formula (I), as well as methods for the treatment of mammals suffering from diseases resulting from autoimmunity and pathological inflammation by administering of a compound having formula (I) to said mammal.
Patent CA-2338901-A1 (CA)
Title: Prevention of migraine recurrence
Inventor: JACKSON NEVILLE COLIN
IPC: A61K31/403
Filed: 1999-06-14
Abstract: The invention relates to the use of eletriptan, or a pharmaceutically acceptable salt or composition thereof, for the manufacture of a medicament for the prevention of migraine recurrence and to the use of a 5-HT1B/1D receptor agonist, or a pharmaceutically acceptable salt or composition thereof, for the manufacture of a dual-, sustained-, delayed-, controlled- or pulsed-release pharmaceutical composition for the prevention of migraine recurrence.
Patent CA-2339007-A1 (CA)
Inventor: ANNE-ARCHARD GILLES
IPC: C07D211/58
Filed: 1999-08-03
Abstract: L'invention concerne un procédé pour la préparation des formes cristallines I et II du (R)-(+)-N-[[3-[1-benzoyl-3-(3,4-dichlorophényl)pipéridin-3-yl]prop-1-yl]-4-phényl pipéridin-4-yl]-N-méthylacétamide (osanétant), ainsi que lesdites formes cristallines I et II de l'osanétant. Préférentiellement, l'osanétant à cristalliser est préparé à partir de son benzènesulfonate.
Patent CA-2339577-A1 (CA)
Title: Optical waveform for use in a dwdm optical network and systems for generating and processing same
Inventor: PAVEL LACRA
IPC: H04B10/08
Filed: 2001-03-06
Abstract: An optical signal occupying one or more wavelengths. An optical data signal on each wavelength is modulated with a respective overhead (dither) signal, resulting in a respective dithered optical signal. The amplitude of a particular overhead signal used to modulate the corresponding optical data signal is chosen so that the RMS value of the overhead signal in the dithered optical signal is proportional to the average intensity of the optical data signal. The instantaneous frequency of each overhead signal is time-varying and each possible frequency belongs to a distinct set of frequencies which are all harmonically related to a fundamental frequency. The distinctness of each set of frequencies allows each overhead signal to be uniquely isolated from an aggregate overhead signal. The harmonic relationship among the frequencies allows improved accuracy of RMS detection at a receiver as well as reduced computational complexity, as each possible frequency for each overhead signal can be made to fall at the center of one of the frequency bins of a single FFT of reasonable size performed at a receiver. Methods and systems for generating and detecting such signals are disclosed.
Patent CA-2340124-A1 (CA)
Title: Customizable orthotic with resilient, dynamic support and simplified adjustable foot cushioning and support shoe insert
Inventor: TOLWIN HINDY KELLERMAN
IPC: A43B7/14
Filed: 2000-05-22
Abstract: An adjustable orthotic (40) comprises a top section (42), a pad section (44) comprising pads (48) and, if desired, a bottom section. The top section has a surface which is disposed to contact a user's foot. The pad section is disposed to rest directly on the footbed of a shoe or through the intermediary of a bottom section on the footbed. The pad section includes at least one pad positioned between the top section and the footbed or bottom section. A hook-and-loop fastening system includes one or more hook members (50) and loop members (52) that releasably secure the pad or pads to at least one of the top section, the bottom section and the footbed. The top section may be formed from a component (56) whose material is of a compressible resilient material and, if desired, a conformable non-compressible component. In the absence of the conformable non-compressible component, the hook member or the loop member is directly adhered to the compressible resilient material. The shoe footbed may be recessed to form a cavity into which the orthotic is placed, to provide the shoe with a slim-line fashionable appearance.
Patent CA-2340780-A1 (CA)
Title: Method of creating authenticated verifiable reproductions of electronic documents
Inventor: PETROGIANNIS TOMMY
IPC: G06F21/64
Filed: 1999-09-24
Abstract: A method is described for creating an authenticated, verifiable reproduction of an electronic document. A master document is first created in a first format, and a DACm is created and linked to or stored with the master document. The master document is then opened and the DAC of the opened document is verified.     If the; DAC of the opened document is equal to DACrn, the reproduction can proceed. The master document is then converted or reproduced into a format different from the first format to make a reproduced document. A DACr is created for the reproduced document, and DACm and DACr are either embedded into the reproduced document or stored in a linked storage system.  Accordingly, two different versions of the master document exist, but each can be verified and authenticated separately. The method of the present invention provides for increased security in an environment where electronic documents can be created in one format and converted into another format.
Patent CA-2343132-A1 (CA)
Title: Improved seal for electrochromic devices
Inventor: TONAR WILLIAM L
IPC: G02F1/15
Filed: 1999-09-20
Abstract: An improved seal member is provided as a part of an electrochromic device to bond two glass elements together in a spaced-apart relationship. In one embodiment the seal member provides improved adhesion to a reflector/electrode on the third surface of an electrochromic mirror, or to a layer of metal on the second or third surface for an electrochromic light filter. This seat member comprises a mixture of an organic resin sealing system and an adhesion promoter, where the adhesion promotor comprises a first and a second region, where the first region interacts with the reflector/electrode or the metal layer, and a second region that interacts with the organic resin sealing system, and may even chemically react with the organic resin sealing system. In another embodiment the seal member is provided with a coefficient of thermal expansion that is closer to glass than a standard epoxy sealing system.
Patent CA-2344703-A1 (CA)
Inventor: KOECHER WOLFGANG
IPC: E04C5/04
Filed: 2001-04-23
Abstract: A Masonry device to facilitate the placement of wire meshing above subflooring. The device enables proper spacing from the subfloor, while providing a rapid means of securing the wire meshing in place. The Stud is fastened to the wire meshing with the blow of a hammer via its specially configured loops.
Patent CA-2348293-A1 (CA)
Inventor: BERARDI ALAIN
IPC: C08F110/02
Filed: 1999-10-21
Abstract: The present invention relates to a process for the polymerisation and copolymerisation of 1-olefins and to a catalyst to be used in said process wherein the catalyst comprises (1) a complex having formula (I) wherein M is Fe[II], Fe[III], Co[I], Co[II], Co[III], Mn[I], Mn[II], Mn[III], Mn[IV], Ru[II], Ru[III] or Ru[IV]; X represents an atom or group covalently or ionically bonded to the metal M; T is the oxidation state of the metal; b is the valency of the atom or group X; and RI  to R7 are each independently selected from hydrogen, halogen, hydrocarbyl, substituted hydrocarbyl, heterohydrocarbyl, substituted heterohydrocarbyl or SiR'3 where each R' is independently selected from hydrogen, halogen, hydrocarbyl, substituted hydrocarbyl, heterohydrocarbyl, substituted heterohydrocarbyl; and when any two or more of R1 to R7 are hydrocarbyl, substituted hydrocarbyl, heterohydrocarbyl or substituted heterohydrocarbyl, said two or more can be linked to form one or more cyclic substituents; (2) an activator which is an alkylalumoxane; and (3) a support material, wherein the atomic ratio of aluminium in the alkylalumoxane (2) to transition metal M in (1) is from 6:1 to 25:1.
Patent CA-2348589-A1 (CA)
Inventor: EVANS JAMES PATRICK
IPC: H05K9/00
Filed: 1998-10-14
Abstract: A shielding enclosure for electronic components, comprises a hollow body, having a sheet metal wall portion (15) and an opening closed by a readily- removable sheet metal panel (9), with interdigitation between an edge zone o f the wall portion (15) and an adjacent edge zone of the panel (9), the interdigitation constituting a U-section channel (14) on the wall portion (1 5) and an interdigitating flange (13) on the panel (9).
Patent CA-2349483-A1 (CA)
Inventor: SIESS THORSTEN
IPC: A61M60/216
Filed: 1999-11-17
Abstract: Disclosed is a blood pump having a pump housing (10) in which an impeller (1 6) is arranged without housing. An external magnetic drive device (33) turns th e impeller (16) via a magnetic coupling (32, 36). The lower side (30) of the wings (19) of the impeller is configured as a support surface (30) which slopes at the following end. A hydrodynamic supporting effect is thus obtain ed during rotation. Said effect raises the impeller (17) from the bottom surfac e of the pump housing (10). As the pump housing does not comprise bearings and  seals, the thrombosis risk and the danger of penetration of foreign bodies into the blood by attrition is reduced.