baber/WOPTO huggingface dataset:
Patent DE-69624898-D1 (DE)
Inventor: GRIFANTINI RENATA
IPC: C07H21/04
Filed: 1996-10-31
Granted: 2003-01-02
Abstract: In an improved process for the preparation of D- alpha -amino acids by the stereoselective conversion of racemic mixtures of 5-substituted hydantoins with an enzymatic system produced by a microorganism, the improvement consists in the fact that a microorganism is used transformed with the plasmid pSM700 cultivated at a temperature of between 20 DEG C and 28 DEG C. The use of this microorganism allows an improvement in the expression of the enzymatic system and an increase in the conversion rate of the racemic hydantoin to D- alpha -amino acid. <IMAGE>
Patent DE-69628685-D1 (DE)
Inventor: KRAEMER ESTEBAN LAKOS
IPC: B01F5/00
Filed: 1996-01-19
Granted: 2003-07-24
Abstract: A process for manufacturing compositions dispensable as sprays, aerosols, characterized by comprising the steps of:   maintaining in a pressurized reactor vessel (5) the active ingredient or mixture of active ingredients and additives of the composition, and a liquified propellant; said additives including dispersion stabilizing surfactant agents of said active ingredients and of the additives in the liquid phase of the propellant, under a nitrogen atmosphere which is free of oxygen; maintaining said mixture under constant recirculation (22,23) under high pressure conditions, forcing said mixture through plates with a plurality of micro-apertures until obtaining a uniform dispersion of the active ingredient, or ingredients, particles; said particles being coated with a film of said stabilizing surfactants agents; completing the volume by adding the necessary propellant to the dispersion obtained in the previous step in order to obtain the final composition; and fractioning the resulting composition into dispensing containers (20) by filling the containers through the dosage valve of the container; said valve being already crimped on each container before filling.   <IMAGE>
Patent DE-69629177-D1 (DE)
Inventor: MILJKOVIC DUSAN
IPC: A61P35/00
Filed: 1996-12-12
Granted: 2003-08-28
Abstract: Methods and compositions are provided which increase the cellular uptake of bioactive materials by covalently bonding such compounds to carbohydrate moieties through chemical linkers using other than glycosidic bonds. Numerous carbohydrates, linkers and bioactive materials can be joined in this way to form novel compositions, which are collectively referred to herein as glinkosides. Preferred glinkosides are preferentially taken up by glucose receptor and/or other cellular receptors, and once inside the cells, the glinkosides are cleaved into a sugar, a linker or linker fragments, and a biologically active compound. Various aspects of the invention include processes for synthesizing glinkosides, glinkoside compositions, and methods of treating diseases using glinkosides.
Patent DE-69629946-D1 (DE)
Inventor: CIMINO W
IPC: A61B18/00
Filed: 1996-04-04
Granted: 2003-10-16
Abstract: A single ultrasonic surgical apparatus can provide a substantial cutting effect on tissue, a substantial coagulation effect on tissue, and an appropriate blend of simultaneous cutting and coagulation effects on tissue. The ultrasonic surgical apparatus is comprised of a handpiece which incorporates a transducer and a surgical tool, a source of electrical energy, a controller, and a switch. The apparatus may be operated at two frequencies within the ultrasonic spectrum, where the first frequency is selected at the low end of the spectrum for enhanced tissue cutting performance, and the second frequency is approximately three times higher for enhanced tissue coagulation performance. The two frequencies may be operated selectively or concurrently, and may be independently adjustable as to amplitude. The transducer may be composed of magnetostrictive or piezoelectric elements. The surgeon to set the desired amplitude of the mechanical vibrations. The transducer is mounted within the handpiece at a location that corresponds to a vibration node common to both the first frequency and the second frequency. Also claimed is a method for use, including the steps of: developing an ultrasonic resonance at a first frequency; developing an ultrasonic resonance at a second frequency which is approximately three times greater than the first frequency; resonating an ultrasonic transducer at the first frequency concurrently with the second frequency; and supporting the transducer where the nodes of vibration at the first frequency are substantially coincident with the nodes of vibration at the second frequency.
Patent DE-69630033-D1 (DE)
Inventor: BECKER S
IPC: C12R1/19
Filed: 1996-06-05
Granted: 2003-10-23
Abstract: Immununological compositions and methods for making and using them. The compositions contain at least one antigen and at least one lipoprotein and optionally an adjuvant. The lipoprotein can itself be antigenic or immunogenic. The antigen can be influenza HA and the lipoprotein a recombinantly expressed product having an OspA leader for lipidation and PspA for the protein portion. The antigen can be OspC and the lipoprotein OspA. The components of the composition are co-administered. A potentiated immunological response is obtained by the compositions and methods.
Patent DE-69637148-D1 (DE)
Inventor: WELT SYDNEY
IPC: C07K14/00
Filed: 1996-08-05
Granted: 2007-08-09
Abstract: This invention relates to isolated proteins and to peptides which are found on the surface of colon cells and colon cancer cells, as well as to nucleic acid molecules encoding said protein and peptides. The protein and peptides bind to tumor associated antibodies, such as mAb 33. The monomeric protein has a molecular weight of about 43 kD as determined by SDS gel electrophoresis under non-reducing conditions. In addition, this invention relates to the use of said nucleic acid molecules, protein, in monomeric or multimeric form, and to antibodies to said peptides in diagnostic, screening and therapeutic methods. This invention further relates to antibodies specific for said protein, in monomeric or multimeric form, and to antibodies to said peptides.
Patent DE-69703882-D1 (DE)
Inventor: BALL H
IPC: B29C65/00
Filed: 1997-04-04
Granted: 2001-02-15
Abstract: A method and apparatus are provided for forming a joint in an elongate article formed from a thermoplastic material, for example an escalator handrail or a conveyor belt, which also includes a plurality of reinforcing cables and a slider fabric. End parts of the article are held in a mold and heated to remelt the material. Portions adjacent the end parts are chilled, at ends of the mold, to prevent remelting. The molten end parts then fuse, and the molten joint is then cooled to resolidify the material and form the joint. With reinforcing cables being present, these can be cut into an interlace pattern, which advantageously is provided in just a layer of the article rather than extending through the full depth of the article. A top layer can then be replaced by a separate top cap of the material of the body of the article. Where a slider is present, to provide an effective interlacing effect, a bottom layer or portion of a handrail is cut at an inclined angle, to form an inclined joint in the slider.
Patent DE-69704150-D1 (DE)
Inventor: HIDEAKI WATASE
IPC: F02M25/00
Filed: 1997-07-04
Granted: 2001-04-05
Abstract: A gas apparatus for internal combustion engine is disclosed in which recovered hydrocarbon gas vapors from the fuel tank and the hydrocarbon with radical hydrocarbon gas vapors from the crankcase, are mixed together with air and alcohol with water solution in an impeller mixing chamber causing modified hydrocarbon gas vapors and oxygen gas vapors to pass through an electronic ionizer producing negatively charged pre-oxidized hydrocarbon gas vapors, then fed through the air induction system to improve mass of air to mass of fuel ratio in an internal combustion engine. A method for production of negatively charged pre-oxidized hydrocarbon gas vapors is also disclosed. <IMAGE>
Patent DE-69705777-D1 (DE)
Inventor: UYTTERHAEGHE LUC
IPC: B60R19/34
Filed: 1997-06-13
Granted: 2001-08-30
Abstract: Thermoplastic part reinforced by a reinforcing sheet showing on one face of the part is prepared using a mould having a principal cavity defining the general shape of the part and secondary cavities (4,5,6) opening into one wall of the principal cavity and defining excrescences (10,11,12) salient to one of the parts faces; and placing in the mould a reinforcing sheet (8), of reinforcing fibres mixed with the thermoplastic, against one wall of the principal cavity with the sheet covering the secondary cavity openings.
Patent DE-69706188-D1 (DE)
Inventor: MERCER W
IPC: C08L53/00
Filed: 1997-10-28
Granted: 2001-09-20
Abstract: A highly thermally conductive but yet highly conformable composition is made from gel filled with alumina. The use of  alpha -alumina in which at least 10 weight % of the  alpha -alumina particles have a particle size of at least 74  mu m makes possible the high filler levels needed to attain high thermal conductivity, without causing the decrease in elongation and softness normally associated with high filler levels. Further improvements are observed if the  alpha -alumina and the gel (or precursor thereof) are mixed with a specific energy input of at least 10 Joule/g. The input of such specific energy has the effect making the resulting composition more conformable than it otherwise would be. The composition may be internally supported by a flexible matrix such as a fabric or open-celled foam.
Patent DE-69712058-D1 (DE)
Inventor: BEDNAR R
IPC: B23D51/00
Filed: 1997-05-06
Granted: 2002-05-23
Abstract: A reciprocating saw having a main body and a spindle mounted in the main body and movable between a retracted position and an extended position. The saw further includes a biasing member operatively associated with the spindle. The biasing member can include a spring that acts on an inner end of the spindle to bias the spindle toward either the extended position or the retracted position.
Patent DE-69726746-D1 (DE)
Inventor: SHERMAN C
IPC: A61B17/58
Filed: 1997-09-24
Granted: 2004-01-22
Abstract: A multi-axial bone screw assembly includes a bone screw having a partially spherical head. The bone screw head is truncated at an upper surface in which a tool receiving recess is defined. The assembly includes a receiver member including a central bore that defines a tapered recess to receive the head of the bone screw. The bore of the receiver member also defines a channel communicating with the recess and configured to receive a spinal rod therein. A portion of the channel is threaded to receive a set screw above the rod. The assembly also includes a crown member disposed between the rod and the head of the bone screw. As the set screw is tightened into the receiver member, the set screw compresses the rod against the crown member, which presses the head of the bone screw into the tapered recess. In one embodiment, the head of the bone screw includes a flared edge that penetrates at least the crown member as the assembly is tightened.
Patent DE-69728706-D1 (DE)
Inventor: WALDRON STEPHEN NORMAN
IPC: F25D3/10
Filed: 1997-02-13
Granted: 2004-05-27
Abstract: A method of controlling the temperature in an enclosure comprises the step of providing means for dispersing a vaporised cryogenic life supporting gas within the enclosure to supplement and/or replace a mechanical refrigeration system 14 normally provided therein. Such cryogenic gas being breathable allows for an operator to enter the enclosure without presenting any hazard thereto. Additionally, the chilling capacity of such a cryogenic system is significantly greater than that available in any presently known mechanical system and hence enhanced overall operation may be achieved. <IMAGE>
Patent DE-69730145-D1 (DE)
Inventor: KIGAWA KOJI
IPC: C12Q1/68
Filed: 1997-08-29
Granted: 2004-09-09
Abstract: A method for targeting, enriching, detecting and isolating a double-stranded nucleic acid target sequence by adding heterologous probes to the reaction system along with the reduced amount of homologous probes in the process of homologous pairing and/or strand exchange between the homologous probe and the target sequence in the presence of a RecA-like recombinase.
Patent DE-69736780-D1 (DE)
Inventor: WEI ZIPING
IPC: C07K14/505
Filed: 1997-08-01
Granted: 2006-11-16
Abstract: This invention provides compositions consisting essentially of a polypeptide and a water-soluble polymer covalently bound thereto at the N-terminal ±-carbon atom via a hydrazone or reduced hydrazone bond, or an oxime or reduced oxime bond. This invention also provides methods of making the instant compositions, pharmaceutical compositions comprising same, and kits for use in preparing same.
Patent DE-69737626-D1 (DE)
Inventor: HAGEN HELGE
IPC: E06B3/66
Filed: 1997-09-08
Granted: 2007-05-31
Abstract: A spacer frame is disclosed having a polygonal, preferably mainly square frame where the frame surrounds glass panes of a sealed glass window unit by forming an upper and a lower horizontal part, at least two side parts, all of which form at least one linear listing or frame. The frame additionally has corresponding asymmetric corner keys and symmetric corner keys, each having legs. The upper horizontal part of the spacer frame preferably has a design which facilitates installation of a mechanism for a blind or pleated sheet which can be fixed underneath the spacer frame thereby hanging between respective panes of the sealed glass unit. The asymmetric corner-keys are connected with one leg to spacer elements and the other leg to the upper horizontal spacer listing elements which has two profile elements. In connection with the spacer element permanent magnets are located in two identical sets positioned on each side of an inner glass pane of the sealed unit. One set of magnets is positioned between the glasses in a holding unit, and one set of corresponding magnets with converse polarity is placed outside the holding unit. Associated with such magnets there is provided a gear assembly for moving and controlling the blind or pleated sheet in a sealed manner between the glass panes of the window.
Patent DE-69801773-D1 (DE)
Inventor: VIGANO' GIORGIO
IPC: B62D1/18
Filed: 1998-12-11
Granted: 2001-10-25
Abstract: The present invention consists in giving access into transportation vehicles, by means of pivoting the major part of the body shell, on low placed lateral axes, in order to facilitate entrance and exit from three sides of the vehicle, including the front side; and without necessity of the space normally required by traditional doors.
Patent DE-69801788-D1 (DE)
Inventor: VIOLI JEAN-CHARLES
IPC: F25D11/00
Filed: 1998-05-12
Granted: 2001-10-31
Abstract: The trolley, for use in a collective catering establishment, has a refrigerated cabinet with an access door (25) for containing a number of ready prepared meals on trays (1). It has a cold generator (37) for keeping the cabinet cool, and a heat source on the inside of a cover (2) on the tray for heating a portion of the meal which is to be eaten hot, fed by an energy transmitting unit. The covered part of the tray is heated in a separate chamber on top of the trolley which takes only one or two trays at the time, and the cover incorporates heat diffusion layers with a coating of black PTFE or enamel.
Patent DE-69802378-D1 (DE)
Inventor: BROWN DAVID
IPC: B62D29/00
Filed: 1998-01-30
Granted: 2001-12-13
Abstract: A clamping device for attaching plastic panels against metallic frames/profiles (3), for use in cabins and vehicles, is provided by inserting an end portion of the plastic panel (1) into a preferably conical pocket (2) in the metal profile (3) and locking it in this position by pushing in a cord (4).
Patent DE-69812865-D1 (DE)
Inventor: VANDERSCHAEGHE ALAIN
IPC: B23K9/04
Filed: 1998-12-24
Granted: 2003-05-08
Abstract: A metallic substrate is corrosion protected by single pass weld cladding with a nickel-chromium-molybdenum alloy of low iron content.   A metallic substrate is protected by single pass welding of a cladding of composition (by wt.) more than 80% Cr + Ni, 8-10% Mo, less than 2.5% Fe and balance metals having no effects on corrosion behavior. An Independent claim is also included for a metallic substrate having a cladding deposited by the above process.
Patent DE-69816801-D1 (DE)
Inventor: PERRAUD OLIVIER
IPC: B60M1/08
Filed: 1998-03-16
Granted: 2003-09-04
Abstract: The invention relates to a ground power supply device for electric vehicles (5), the device including power supply segments (52) insulated from each other and each having a length less than half the length of the footprint of the vehicle (5), and being adapted to apply a supply voltage to a segment (52) only when said segment (52) is within the footprint of the vehicle (5), the vehicle (5) having a power supply rubbing member (80), and the device being adapted to apply the supply voltage to two adjacent segments (52) when the rubbing member (80) is in simultaneous contact with the two segments (52) and to earth one of the two segments (52) a short time after said rubbing member (80) has left that segment (52).
Patent DE-69816923-D1 (DE)
Inventor: VAN STRATEN ADRIANUS PETRUS MA
IPC: A47J31/44
Filed: 1998-09-29
Granted: 2003-09-11
Abstract: According to the method for preparing frothed milk or café crème, milk concentrate or coffee concentrate is mixed with water, using a venturi chamber. The venturi chamber comprises a water inlet (56a), a concentrate inlet (54a) and an outlet (88a). Further, a whirl chamber, located downstream of the venturi chamber, is used, which is in fluid communication with the outlet. The water is supplied under pressure via the water inlet to the venturi chamber, so that a reduced pressure is created in the venturi chamber. The concentrate inlet is brought into fluid communication with a stock of milk or coffee concentrate, so that, as a result of the reduced pressure in the venturi chamber, via the concentrate inlet, milk or coffee concentrate is sucked into the venturi chamber. The milk or coffee concentrate and the water then flow together via the outlet to the whirl chamber, and the milk or coffee concentrate and the water are beaten in the whirl chamber to form frothed milk or café crème. <IMAGE>
Patent DE-69824097-D1 (DE)
Inventor: LESENNE YVES
IPC: B65D85/18
Filed: 1998-08-04
Granted: 2004-07-01
Abstract: The procedure consists of placing the gloves (30) flat on two neighboring supports (1,2) positioned so that part of the gloves is on one and another part on the other. A separator card (10) is then placed on one part of the gloves. The other part is folded over onto the card, and the folded gloves and card are moved towards a packaging unit. At least one of the two supports is in the form of a belt or roller mechanism which is used to pass the folded gloves to the packaging unit, where they are enclosed between two layers of welded and thermo-shrink film in a rigid surround with a suspension ring.
Patent DE-69829197-D1 (DE)
Inventor: GOLDBLATT LEONARD
IPC: C08F255/00
Filed: 1998-10-28
Granted: 2005-04-07
Abstract: Methods are disclosed for making graft copolymers. The methods comprise the steps of: (a) providing (i) an ethylene/propylene (EP) copolymer or other graftable polymer, (ii) an ethylenically unsaturated sulfur-, nitrogen- and/or oxygen-containing monomer, and (iii) an amount of an initiator sufficient to graft said monomer and EP copolymer or other graftable polymer, (b) introducing said EP copolymer or other graftable polymer into an extruder; (c) introducing said monomer into the extruder; (d) introducing said initiator into the extruder, wherein at least one of the above-identified reactants in (a) is introduced in the presence of a polar solvent; and (e) reacting said EP copolymer or other graftable polymer, monomer and initiator by operating said extruder, thereby forming the graft copolymer. This invention also relates to methods of making a dispersant viscosity index improver and methods for making a lubricating oil. This invention further relates to graft copolymer products made by the aforementioned methods.
Patent DE-69839601-D1 (DE)
Inventor: MOTTRAM DONALD STEWART
IPC: A23L27/20
Filed: 1998-03-18
Granted: 2008-07-24
Abstract: Compositions for generating a cooked flavor in a foodstuff, comprising specified flavor precursors that react on heating to generate the flavor and maintain a reactive association after inclusion in the foodstuff. The compositions may include combination of a sulphur source, e.g. hydrogen sulphide, methane thiol, a sulfur-containing amino acid, thiamine, cystine, sodium sulphide, ammonium sulphide, ammonium polysulphide, onions, garlic, shallots, eggs, methionine, and mixtures thereof, and at least one reductone, e.g. a furanone, a ketone, a pyrone, an aldehyde, a carbonyl compound, isomaltol, maltol, pyruvaldehyde, hydroxyacetone, 3-deoxyglucosone, 5-hydroxy-5,6-dihydromaltol, 2,3-butanedione, 3-hydroxy-2-butanone, a process flavor, cooked vegetable concentrates, soy sauce, and mixtures thereof.
Patent DE-69840911-D1 (DE)
Inventor: TANIGUCHI SHIGERU
IPC: A61K31/74
Filed: 1998-06-19
Granted: 2009-07-30
Abstract: A gelled composition prepared by adding a gelling component to a carrier for adsorption. The composition can significantly improve the taste of the carrier for adsorption, can reduce the dosage, and can be easily administered to a patient.
Patent DE-69842234-D1 (DE)
Inventor: SAARI ALBERT L
IPC: G10D3/00
Filed: 1998-06-08
Granted: 2011-06-01
Abstract: A gun case humidity control device for use in maintaining a desired humidity in the gun case, the device including a protective case, a water vapor permeable pouch and a thickened saturated solution, the solution having a suitable humidity control point.
Patent DE-69903842-D1 (DE)
Inventor: KOMOROWSKI S
IPC: F16H7/12
Filed: 1999-09-15
Granted: 2002-12-12
Abstract: A belt tensioner for tensioning a belt for a motor vehicle comprises a pivot shaft, a pivoting structure mounted for pivotal movement on the pivot shaft, and a pulley mounted for rotation on the pivoting structure. A spring biases the pivoting structure in a direction that moves the pulley mounted on the pivoting structure into tensioning engagement with the belt. A bolt is constructed and arranged to mount the belt tensioner on the motor vehicle engine mount. The bolt is constructed and arranged to be tightened to a predetermined extent for installing the tensioner of the motor vehicle, the predetermined extent is the same extent to which the bolt is tightened during normal operation of the tensioner. A clamping structure applies a predetermined clamping force on the pivot shaft after the bolt is tightened to the predetermined extent. The predetermined clamping force is sufficiently large to maintain the pivot shaft in perpendicular relation to the engine mount and prevent tilting of the pivot shaft when the tensioner is moved into installed tensioning engagement with the belt, yet sufficiently small to permit manual movement of the pivot shaft relative to the mounting bolt for adjusting the amount of tension applied by the tensioner to the belt.
Patent DE-69908584-D1 (DE)
Inventor: FERRUTI PAOLO
IPC: A61K47/48
Filed: 1999-04-28
Granted: 2003-07-10
Abstract: The present invention relates to a non crosslinked block polymer. It also relates to a process for the preparation thereof and to the use thereof particularly in pharmaceutical compositions. The block polymer according to the invention contains sequences of polyethylene glycol linked to sequences of polyester and/or polycarbonate. The polyester sequences are selected in particular from polyfumarate, polymaleate and polysuccinate sequences.