baber/WOPTO huggingface dataset:
Patent AT-E326972-T1 (AT)
Inventor: UENO RYUJI
IPC: A61K31/557
Filed: 1998-09-30
Granted: 2006-06-15
Abstract: Combined administration of isopropyl unoprostone and Latanoprost enhances their ocular hypotensive effect synergistically.
Patent AT-E207563-T1 (AT)
Inventor: HABE WOLFGANG
IPC: E02D5/76
Filed: 1999-03-24
Granted: 2001-11-15
Abstract: The assembly has a tie (5) in a drilled hole in spaced fixing positions, axially symmetrical to the drilling. In a single fixing position, the mounting assembly consists of an one-piece belt (1) which is closed by a belt lock (17). The belt is formed of bend-resistant hinged (18) links (8) which are provided with clamps (9) for the tie.
Patent AT-E226910-T1 (AT)
Inventor: POHLER ANDREAS
IPC: B65D83/44
Filed: 1999-09-22
Granted: 2002-11-15
Abstract: The device has a connecting channel(14) on the axially movable tube section(5) in the spray head housing and which by movement of the tube section relative to the spray head is selectively connected to only one feed channel(13) or simultaneously to both feed channels(12,13) so as to supply one(11) or both(10,11) nozzles. The connecting channel is an annular cut-out in the outer region(16) of the tube section, and its extent in the operating direction is greater than or the same as the spacing of the feed channels.
Patent AT-E227660-T1 (AT)
Inventor: STREUBEL WOLFGANG DIPL-ING
IPC: B60K15/035
Filed: 1999-09-25
Granted: 2002-11-15
Abstract: The vehicle has a fuel tank (1) with refueling tube (4), operational ventilation tube (11), and refueling ventilation tube (12). Operational and/or refueling ventilation tubes are components of a multi-channel tube (9). The multi-channel tube also contains the refueling tube, a compensation vessel, and an expansion compensator.
Patent AT-E285085-T1 (AT)
Inventor: SZYMANSKI JACEK
IPC: G05B19/02
Filed: 1999-07-27
Granted: 2005-01-15
Abstract: Characteristic values for an industrial control process are stored in field units (1 -3), each equipped with an HTTP server (7) enabling the unit to construct, in response to an external request, an HTML page in which the values are embedded. Real time updating of the values is performed using either locally acquired data or that obtained over the communication network.
Patent AT-E260684-T1 (AT)
Inventor: BRANDENBERGER HARRY
IPC: A61M5/148
Filed: 1999-03-30
Granted: 2004-03-15
Abstract: The unit for advancing liquids in a sterile, non-pulsating manner, from or in a process chamber, comprises a container (11) which can be closed off with respect to the surroundings, and which has a member (1,4,7) for connecting a bag (10) inside it. The bag is used to hold or deliver the liquid. The inner chamber is connected to a pump (21) by a second member which is used to deliver an incompressible medium. The container has a support for the bag.
Patent AT-E236390-T1 (AT)
Inventor: PHILLIPS ROGER
IPC: G01N27/24
Filed: 1999-02-03
Granted: 2003-04-15
Abstract: The integrity and quality of the internal or inside coating of a container, such as a can, is measured by attaching an electric terminal to the can, inserting an electrode into the can, applying an electric signal to either the electric terminal or the electrode, and measuring the current flowing between the terminal and the electrode as an electrolyte is being added to the can. By measuring the electric signal as the level of electrolyte is being varied, an indication can be achieved of the quality and integrity of the coating at various parts of the can.
Patent AT-E364333-T1 (AT)
Inventor: MCCALLUM TIMOTHY P
IPC: A42B1/24
Filed: 1999-02-12
Granted: 2007-07-15
Abstract: A hat has a storage pocket on the inside of the hat which is located entirely within a dead space at the front portion of the hat extending from a location spaced above a hat band towards the crown of the hat. When a hat is worn, there will be a dead space inside the hat where the hat does not contact the wearer's head, which typically extends from a location just above the hat band to the crown of the hat, due to the difference in curvature between the wearer's head and the hat itself. By positioning a storage pocket in this area, unsightly bulges are avoided, as well as discomfort due to stored items pressing against the wearer's head.
Patent AT-E375510-T1 (AT)
Inventor: NIENABER VICKI
IPC: G01N33/50
Filed: 1999-03-05
Granted: 2007-10-15
Abstract: X-ray crystallography can be used to screen compounds that are not known ligands of a target biomolecule for their ability to bind the target biomolecule. The method includes obtaining a crystal of a target biomolecule; exposing the target biomolecule crystal to one or more test samples; and obtaining an X-ray crystal diffraction pattern to determine whether a ligand/receptor complex is formed.The target is exposed to the test samples by either co-crystallizing a biomolecule in the presence of one or more test samples or soaking the biomolecule crystal in a solution of one or more test samples. In another embodiment, structural information from ligand/receptor complexes are used to design ligands that bind tighter, that bind more specifically, that have better biological activity or that have better safety profile.A further embodiment of the invention comprises identifying or designing biologically-active moieties by the instant process.In a further embodiment, a biomolecule crystal having an easily accessible active site is formed by co-crystallizing the biomolecule with a degradable ligand and degrading the ligand.
Patent AT-E242935-T1 (AT)
Inventor: NAVALON CARRETERO HERMINIO
IPC: H02P7/29
Filed: 1999-04-15
Granted: 2003-06-15
Abstract: An electronic regulator is presented based on the pulse width modulation (PWM) of a rectangular wave signal of low frequency, with which the speed of a direct current motor is controlled. The object of the invention is that of simplifying the design of the regulator eliminating the classic inductive element, so that the same direct current motor functions as the filter of the output signal provided by the switching component. It is equally an objective of the invention to avoid the noises produced by the switching, for which it works with subsonic switching frequencies, below 50 Hz. <IMAGE>
Patent AT-E215097-T1 (AT)
Inventor: VAN DER LUGT JAN PIETER
IPC: C07B33/00
Filed: 1999-05-04
Granted: 2002-04-15
Abstract: Primary alcohols, especially in carbohydrates, can be selectively oxidized to aldehydes and carboxylic acids in a low-halogen process by using a peracid in the presence of a catalytic amount of a di-tertiary-alkyl nitroxyl (TEMPO) and a catalytic amount of halide. The halide is preferably bromide and the process can be carried out at nearly neutral to moderately alkaline pH (5-11). The peracid can be produced or regenerated by means of hydrogen peroxide or oxygen. The process is advantageous for producing uronic acids and for introducing aldehyde groups which are suitable for crosslinking and derivatization.
Patent AT-E254952-T1 (AT)
Inventor: GRIFFIN JAMES W
IPC: B32B27/30
Filed: 1999-07-08
Granted: 2003-12-15
Abstract: A laminate product is provided. The laminate product includes a first layer of porous expanded polytetrafluoroethylene membrane, and a second layer of woven fabric of polytetrafluoroethylene containing yarn. The membrane preferably has an air permeability of at least 0.01 cfm/ft2 at 0.5 inch water gauge, and a thickness of greater than about 0.5 mil. The woven fabric preferably has a weight of between about 15 ospy and about 30 ospy. The laminate product can be sewn to provide a filter bag for use in pulse jet filter applications.
Patent AT-E304375-T1 (AT)
Inventor: MELIEF CORNELIS J M
IPC: C12N15/09
Filed: 1999-05-21
Granted: 2005-09-15
Abstract: Disclosed is a method and composition for treating tumors or infectious diseases, wherein the composition includes CD40 binding molecules together with CTL-activating peptides, e.g., tumor antigens. Such composition is useful for enhancing the anti-tumor affect of a peptide tumor vaccine, or for otherwise activating CTLs so that the activated CTLs can act against tumurous or infected cells. The CD40 binding molecules can include antibody molecules, as well as homologues, analogues and modified or derived forms thereof, including immunoglobulin fragments like Fab. (Fab')2 and Fv, as well as other molecules including peptides, oligonucleotides, peptidomimetics and organic compounds which bind to CD-40 and activate the CTL response.
Patent AT-E376859-T1 (AT)
Inventor: IDEKER RAYMOND E
IPC: A61B5/0402
Filed: 1999-09-15
Granted: 2007-11-15
Abstract: An implantable system for detecting electrical activity from a patient's heart comprises a first sensing electrode configured for positioning through the coronary sinus ostium and within a vein on the left surface of the left ventricle of the heart for sensing electrical activity from the heart, and a detector operatively associated with the first sensing electrode for determining (e.g., diagnosing or prognosing) a medical condition of the heart with the sensed electrical activity. Typically the system further comprises a second sensing electrode configured for positioning in the right ventricle of the heart, where the detector is operatively associated with both the first sensing electrode and the second sensing electrode. The second sensing electrode may be positioned in other locations as well, such as also within a vein on the left surface of the left ventricle of the heart (although spaced apart from the first sensing electrode), in the right atrium, in the superior vena cava, etc. Finally, a third sensing electrode may also be included, with the third electrode positioned in any of the foregoing locations (again, spaced apart from the first and second electrodes), with the detector operatively associated with all of the first, second, and third sensing electrodes. Determination of a medical condition may be carried out by any suitable means, such as by detecting premature beats in the heart. The method is particularly useful for identifying the chamber of premature beat origin.
Patent AT-E220966-T1 (AT)
Inventor: SCHROEDER REINHARD
IPC: B23B19/02
Filed: 1999-10-28
Granted: 2002-08-15
Abstract: A controlled spindle drive is utilized for producing an axially acting clamping force for the purpose of clamping/releasing tools or workpieces on the work spindle of machine tools. A two-part spindle shaft is enclosed coaxially by a ring which can be displaced axially between two end positions. In one end position, the ring connects the two spindle-shaft parts to form a spindle shaft, which acts as a whole, for a normal operation as a machine spindle. In the other end position, the spindle-shaft part with the tool or workpiece mounting, is connected in a fixed manner to the non-rotating spindle housing. The non-secured spindle-shaft part then acts exclusively on the task-specific clamping/release mechanism. The controlled spindle drive, which acts on the non-secured spindle-shaft part, can actuate the clamping mechanism exclusively. Instead of the axially displaceable, coaxially disposed ring, it is possible to use a second controlled spindle drive which drives the spindle-shaft part with the tool or workpiece mounting independently. The drive operations for the two drives are coupled via an axis interpolation.
Patent AT-E288612-T1 (AT)
Inventor: ARNDT RAINER
IPC: B32B3/30
Filed: 1999-12-06
Granted: 2005-02-15
Abstract: The invention relates to a multilayer insulation element (1) comprising a non-woven material layer (4, 6) and a cellular material layer (5). Said layers are arranged on top of each other. According to the invention, the cellular material layer (5) consists of uneven, three-dimensional structured polyimide cellular material in order to meet the requirements such as high sound absorption or sound insulation and/or high heat insulation and/or low liquid water formation at high temperature gradients and/or low surface weight and/or good handleability as fitting elements.
Patent DE-02723813-T1 (DE)
Title: Teststreifen zur bestimmung multipler analyten mit parallelem probenzufuhrsystem
Inventor: ROBERTSON L
IPC: G01N33/543
Filed: 2002-04-08
Abstract: Analysetestvorrichtung mit:  einem Gehäuse, einschließlich eines Vertiefungsteils, der ein Zuführungselement mit mindestens einem Zuführungseinlass festlegt; und  einer Testanordnung, die im Gehäuse angeordnet ist und eine Vielzahl von Testelementen und ein Probenkontaktkissen in Kontakt mit jedem der Vielzahl von Testelementen umfasst; und  einem Zuführungselement zum Steuern einer Rate einer Fluidprobenfreisetzung aus dem Vertiefungsteil an das Probenkontaktkissen.
Patent DE-132084-T1 (DE)
IPC: A22C17/04
Filed: 1984-07-04
Abstract: Apparatus for the separation of mixtures of materials of different consistencies, such as meat and bone, or sewage containing solid material, comprises a positive displacement pump (28) feeding the pressurised mixture to a separator (70) which can be separate from the pump or an integral part of its structure. The pump comprises a rotary vaned pump with radially-moving vanes (54a, 54b) of fixed length operating with both their ends always in sealing engagement with the wall of an internal cam (38) also constituting a wall of the pump chamber. The vanes are provided with cutting edges (64) able to shear material such as bone that enters the pump, so that the pump is not jammed thereby.
Patent DE-330433-T1 (DE)
IPC: G01N33/533
Filed: 1989-02-22
Abstract: A method of preparing a labelled specific binding partner, such as a biological probe in the form of an antibody or oligonucleotide probe, using a protected label the corresponding unprotected label being susceptible to inactivation, such as by hydrolysis to yield a non-chemiluminescent form of the label. The specific binding partner is linked to the label, and an adduct of the label is prepared using a protective adduct former which produces a protected label which is less susceptible to inactivation. Particularly preferred labels are the acridiniums and acridans, most preferably the former having the general structure: <CHEM> wherein the phenyl rings are optionally additionally substituted, R1 is preferably an alkyl, and R5 is an optionally substituted hydrocarbon, most preferably a phenyl moiety which is either linked to the specific binding partner, or capable of being linked thereto. Formation of the protected label is preferably an equilibrium reaction which is readily reversible, such as by dilution or oxidation of the protective adduct former. Labels useful in such a method are also disclosed.
Patent ES-2103250-T1 (ES)
Title: Articulos de proteccion polimericos detectables, procedimiento de preparacion y sus aplicaciones.
Inventor: DE RICCI SOPHIE
IPC: G01V15/00
Filed: 1996-11-08
Abstract: ARTICULO DE PROTECCION POLIMERICO HABITUALMENTE UTILIZADO EN LAS CADENAS DE FABRICACION, DE TRANSFORMACION O DE ACONDICIONAMIENTO, PARTICULARMENTE EN EL CAMPO AGROALIMENTARIO, FARMACEUTICO O ALIMENTARIO, DICHO ARTICULO CONTIENE, REPARTIDO DE MANERA HOMOGENEA EN SU CONJUNTO, UN MATERIAL QUE TIENE PROPIEDADES CONDUCTORAS Y/O MAGNETICAS, DETECTABLE POR UN DETECTOR DE PARTICULAS METALICAS. PROCEDIMIENTO DE PREPARACION DE DICHO ARTICULO.
Patent CY-1107525-T1 (CY)
Title: Αναστολεiς μεταλλοπρωτεϊνασης
Inventor: ERIKSSON ANDERS
IPC: A61P9/00
Filed: 2006-10-13
Abstract: Ενώσεις του τύπου (I) όπου το z είναι SO2 ή SO, χρήσιμες ως αναστολείς μεταλλοπρωτεϊνάσης, ιδιαίτερα ως αναστολείς του ΜΜΡ12.
Patent CY-1107621-T1 (CY)
Inventor: CHIEN DAVID Y
IPC: G01N33/576
Filed: 2007-04-26
Abstract: The present invention is directed to assays for detecting antibodies in a sample in a single incubation step. The assays employ universal solid phases and/or universal detectable markers, and facilitate the detection and differentiation of antigens from the same source or from different sources in a single test sample. The present invention includes test kits for performing the methods according to the invention.
Patent CY-1107672-T1 (CY)
Inventor: DI PIERRO FRANCESCO
IPC: A61K8/49
Filed: 2007-06-14
Abstract: The present invention relates to pharmaceutical and/or cosmetic compositions containing a combination of the following active principles: a) complex of escin/beta-sitosterol with phospholipids, b) complex of Gingko biloba dimeric flavonoids with phospholipids, c) complex of Centella asiatica triterpenes with phospholipids, and optionally one or both of: d) ethyl ximeninate e) Coleus forskolii standardized extract.
Patent CY-1110367-T1 (CY)
Inventor: HEINEMEIER JÜRGEN
IPC: B31B50/62
Filed: 2008-06-24
Abstract: The flexible plastics packaging bag has a single wall enclosing a space (14) for a substance which may give off gas. The gas pressure relief system consists of a double-wall zone with holes (12) for pressure relief in the inner wall (5). Molded projections may act as spacers for the outer wall (6) defining a gas escape zone (4). The edges (2,3) of the outer wall are held in place by welded or glued seams (7,8). A section of welded seam contains a separating material (11) and may give way to release the gas if the pressure builds up.
Patent CY-1110177-T1 (CY)
Title: Ω-καρβοξυαρυλο υποκατεστημενες διφαινυλουριες ως αναστολεις της raf κινασης
Inventor: RIEDL BERND
IPC: C07D211/78
Filed: 2010-06-10
Abstract: Η εφεύρεση αυτή σχετίζεται με τη χρήση μιας ομάδας αρυλουριών στη θεραπεία ασθενειών στις οποίες μεσολαβεί raf κινάση, και με φαρμακευτικές συνθέσεις για χρήση σε τέτοια θεραπεία.
Patent CY-1110739-T1 (CY)
Inventor: BILLIET-PRADES YVES
IPC: A61J1/00
Filed: 2010-08-17
Abstract: The bushing (190) has a receptacle (16) to receive a dropper neck of a vial with a product and including a shape matching the neck. A body (191) has an upper portion (2) cooperating with the neck part and a lower portion (3) to cover a neck of another vial with another product. The receptacle section varies by decreasing from the portion (2) till the portion (3) for being cooperated with the dropper neck. A stopper (110) has a shape that is complementary to that of the receptacle. A lid cooperates with an external part of the body. The body, stopper and lid are molded in plastic material.
Patent CY-1112209-T1 (CY)
Inventor: PETERS JÖRG
IPC: C07K14/81
Filed: 2011-03-29
Abstract: A method for renaturation of proteins comprising adding to a solution of denatured, chemically modified or reduced proteins a refolding buffer containing a primary, secondary or tertiary amine. Said method has been applied, for example, to Interleukin-4 and bovine pancreatic trypsin inhibitor (BPTI), which were previously (i) solubilized in the presence of guanidinium hydrochloride as chaotropic agent, and (ii) subjected to sulfitolysis.
Patent CY-1114436-T1 (CY)
Title: Μεθοδος μεταφορας ενος αγωγου σε ενα πολλαπλο συστημα αγωγων
Inventor: BALK WILHELMUS HENDRIKUS JOHANNES
IPC: F17D1/00
Filed: 2012-03-14
Abstract: Η παρούσα εφεύρεση σχετίζεται με μια συσκευή και μέθοδο παραγωγής αεριούχου και υγρού συστατικού ρεύματος που ρέει σε τουλάχιστον δύο πολυφασικά, ρέει σε τουλάχιστον δύο αγωγούς, η μέθοδος περιλαμβάνει τουλάχιστον δύο βήματα των: (α) πέρασμα του πρώτου πολυφασικού στον πρώτο αγωγό (10) και μέσα από το πρώτο σύστημα Φύλαξης Τεμαχίου Μετάλλου (12), (β) πέρασμα του δεύτερου πολυφασικού ρεύματος στον δεύτερο αγωγό (20) και ένα δεύτερο σύστημα Φύλαξης Τεμαχίου Μετάλλου (22), (γ) πέρασμα της πρώτης ράβδου χυτού μετάλλου (9) στον πρώτο αγωγό (10) για να δημιουργήσει μια πρώτη ράβδο χυτού τεμαχίου μετάλλου μαζικά στον πρώτο αγωγό και (δ) πέρασμα τουλάχιστον ενός κλάσματος του πρώτου πολυφασικού ρεύματος να ρέει από την πρώτη ράβδο χυτού τεμαχίου μετάλλου στον δεύτερο αγωγό (20) σε μια διασχίζουσα γραμμή (30).
Patent CY-1115721-T1 (CY)
Inventor: MIELE SERGIO
IPC: C05G3/90
Filed: 2014-11-07
Abstract: Localized fertilization with excellent results is obtained through the use of a microgranular fertilizer composition where the composition granules have size within the range of 0.1 to 1.5 mm.
Patent CY-1116695-T1 (CY)
Title: Συνθεση περιεχοντας υπερ-μικρονοποιημενο παλμιτοϋλ-αιθανολαμιδιο
IPC: A61K9/14
Filed: 2015-09-16
Abstract: Η παρούσα εφεύρεση σχετίζεται με μια σύνθεση για φαρμακευτική ή κτηνιατρική χρήση, περιλαμβάνοντας παλμιτοϋλαιθανολαμίδιο. Ειδικότερα, η παρούσα εφεύρεση σχετίζεται με μια φαρμακευτική σύνθεση για ανθρώπινη ή κτηνιατρική χρήση, περιέχοντας μια θεραπευτικώς αποτελεσματική ποσότητα παλμιτοϋλαιθανολαμιδίου στην υπερ-μικρονοποιημένη μορφή, όπου περισσότερο από το 90% κατά βάρος παλμιτοϋλαιθανολαμίδιο έχει μεγέθη σωματιδίων χαμηλότερα από τα 6 μικρά, μαζί με φαρμακευτικώς αποδεκτά έκδοχα.
Patent CY-1118184-T1 (CY)
Title: Μεθοδοι συνθεσης και/ή καθαρισμου ενωσεων διαμινοφαινοθειαζινιου
Inventor: WISCHIK CLAUDE MICHEL
IPC: C07D279/18
Filed: 2016-11-03
Abstract: Η εφεύρεση αυτή σχετίζεται γενικά με το πεδίο της χημικής σύνθεσης και καθαρισμού, και ειδικότερα με μεθόδους σύνθεσης και/ή καθαρισμού ορισμένων ενώσεων του 3,7 διαμινο-φαινοθειαζιν-5-ίου (αναφερόμενες στο παρόν ως «ενώσεις διαμινοφαινοθειαζινίου») περιλαμβάνοντας Χλωριούχο Μεθυλοθειονίνιο (MTC) (επίσης γνωστό ως Μπλε του Μεθυλενίου). Η παρούσα εφεύρεση επίσης σχετίζεται με τις προκύπτουσες (υψηλής καθαρότητας) ενώσεις, συνθέσεις οι οποίες τις περιλαμβάνουν (π.χ., δισκία, κάψουλες), και τη χρήση τους σε μεθόδους εξουδετέρωσης παθογόνων, και μεθόδους ιατρικής αντιμετώπισης, προφύλαξης και διάγνωσης, κλπ., για παράδειγμα, μιας ταυπάθειας˙ μιας νόσου συσσώρευσης της tau πρωτεΐνης˙ νόσου Alzheimer (AD)˙ νόσου Pick˙ Προϊούσας Υπερπυρηνικής Παράλυσης (PSP)˙ μετωποκροταφικής άνοιας (FTD)˙ FTD και παρκινσονισμού σχετιζόμενου με το χρωμόσωμα 17 (FTDP-17)˙ συμπλέγματος άρσεως αναστολών-άνοιας-παρκινσονισμού-αμυοτροφίας (DDPAC)˙ εκφύλισης της ωχράς σφαίρας, της γέφυρας, της μέλαινας ουσίας (PPND)˙ Guam-ALS συνδρόμου˙ εκφύλισης της ωχράς σφαίρας, της μέλαινας ουσίας, του σωματίου του Luys (PNLD)˙ φλοιοβασικής εκφύλισης (CBD)˙ ήπιας γνωστικής βλάβης (MCI)˙ καρκίνου του δέρματος˙ μελανώματος˙ μεθαιμοσφαιριναιμίας˙ μιας ιικής μόλυνσης˙ μιας βακτηριακής μόλυνσης˙ μιας πρωτοζωικής μόλυνσης˙ μιας παρασιτικής μόλυνσης˙ ελονοσίας˙ σπλαγχνικής λεϊσμανίασης˙ Αφρικανικής ασθένειας ύπνου˙ τοξοπλάσμωσης˙ γιαρδίασης˙ νόσου του Chagas˙ μόλυνσης από ιό Ηπατίτιδας C (HCV)˙ μόλυνσης από ιό ανθρώπινης ανοσοανεπάρκειας (HIV)˙ μόλυνσης από ιό του Δυτικού Νείλου (WNV)˙ μιας συνουκλεϊνοπάθειας˙ νόσου Parkinson (PD)˙ άνοιας με σωμάτια Lewy (DLB)˙ ατροφίας πολλαπλών συστημάτων (MSA)˙ επαγόμενου από φάρμακα παρκινσονισμού˙ και ανεπάρκειας του αυτόνομου (PAF).
Patent CY-1119073-T1 (CY)
Title: Ισομορφες γλυκοζυλιωσης ανθρωπινης ιστικης καλλικρεινης 1
Inventor: CHARLES MATTHEW
IPC: A61P3/10
Filed: 2017-05-03
Abstract: Παρέχονται παρασκευάσματα γλυκομορφών ανασυνδυασμένης ανθρώπινης ιστικής καλλικρεϊνης-1 (rhKLK1) οι οποίες έχουν έναν καθορισμένο αριθμό μονάδων ολιγοσακχαρίτη ανά KLK1 μόριο. Επίσης παρέχονται μείγματα τέτοιων γλυκομορφών, φαρμακευτικές συνθέσεις οι οποίες περιέχουν τέτοιες γλυκομορφές ή μείγματα αυτών, μέθοδοι λήψης των rhKLK1 γλυκομορφών, και θεραπευτικές χρήσεις αυτών.
Patent CY-1119221-T1 (CY)
Inventor: KREUTZER ROLAND
IPC: C12N15/11
Filed: 2017-06-15
Abstract: A new method to inhibit the expression of a predetermined target gene in a cell, comprises introducing an oligoribonucleotide with double stranded structure (dsRNA) or a vector coding for the dsRNA into the cell, where a strand of the dsRNA is at least in part complementary to the target gene. ACTIVITY : Antiviral; cytostatic; anti-prion. MECHANISM OF ACTION : Double stranded RNA inhibitor of gene expression.
Patent CY-1121027-T1 (CY)
Title: Θeieno[2,3-c]πypania ως διαμορφωτες cftr
Inventor: VAN DER PLAS STEVEN EMIEL
IPC: C07D495/04
Filed: 2018-12-12
Abstract: Η παρούσα εφεύρεση αποκαλύπτει ενώσεις σύμφωνα με το Χημικό Τύπο I: Όπου το R είναι ως καθορίζεται εις το παρόν. Η παρούσα εφεύρεση σχετίζεται με ενώσεις και με τη χρήση αυτών στην αγωγή της κυστικής ίνωσης, με μεθόδους για την παραγωγή αυτών, με φαρμακευτικές συνθέσεις περιλαμβάνοντας τις ίδιες, και με μεθόδους αγωγής κυστικής ίνωσης μέσω χορήγησης μιας ένωσης της εφεύρεσης.