baber/WOPTO huggingface dataset:
Patent CN-1243822-A (CN)
Inventor: ZHENG YAN
IPC: C07C211/63
Filed: 1999-04-09
Abstract: 本发明涉及一种阳离子聚合物单体二甲基二烯丙基氯化铵的制备方法。它是用等摩尔配比的氯丙烯、二甲胺和氢氧化钠为原料,用密闭低压、高温、带压交替加碱和氯丙烯的一步法合成二甲基二烯丙基氯化铵。本制备方法不分离中间产物,操作步骤少,反应速度快、收率高、成本低、无“三废”排放。本单体主要用于合成含有机阳离子的水溶性聚合物,如用于合成新型聚合物驱油剂和钻井液处理剂、水处理剂和杀菌剂,以及作为日化和造纸工业的原料。
Patent CN-1269141-A (CN)
Title: 一种植物生长混合调节剂的生产方法
Inventor: TANG GENGJI
IPC: A01N63/00
Filed: 1999-04-05
Abstract: 一种植物生长混合调节剂的生产方法,涉及到一种植物生长混合调节剂生产方法及用该法生产的一种植物生长的混合调节剂,其特征是用脱酰几丁质、谷氨酸、春雷霉素、井岗霉素及化学原料、动物骨粉萃取液复合而成。实现了用添加剂浸(拌)种育苗,可提高单产12%以上,叶面喷施可提高单产8—10%以上,施用瓜果、蔬菜效果更佳。适宜农村及农业使用。
Patent CR-20120443-A (CR)
Title: Derivados de (imidazopirimidina-7-il)-heteroarilamida y su uso como inhibidores de pde10a
Inventor: ALVAREZ SANCHEZ RUBEN
IPC: A61K31/519
Filed: 2012-08-24
Abstract: La invención se refiere a nuevos derivados de imidazopirimidina de la fórmula (I) en la que R1, R2 y R8 tienen los significados definidos en la descripción y en las reivindicaciones, así como a sus sales y ésteres fisiológicamente aceptables. Estos compuestos inhiben la PDE10A y pueden utilizarse como medicamentos.
Patent CR-20130139-A (CR)
Title: Derivados de 4-(5-ciano-pirazol-1-il)-piperidina como moduladores de gpr 119
Inventor: MASCITTI VINCENT
IPC: A61K31/454
Filed: 2013-03-22
Abstract: En la presente se describen compuestos que modulan la actividad del receptor GPR119 acoplado a la proteína G y sus usos para el tratamiento de enfermedades relacionadas con la modulación del receptor GPR119 acoplado a la proteína G en animales.
Patent CR-20140446-A (CR)
Title: Un concepto novedoso de soldadura fuerte
Inventor: SJÖDIN PER
IPC: C22C19/00
Filed: 2014-09-25
Abstract: La presente invención se refiere a una mezcla de por lo menos una fuente de boro y por lo menos una fuente de silicio, en donde la mezcla comprende boro y silicio en una relación en peso de boro a silicio dentro de un intervalo de aproximadamente 5:100 a aproximadamente 2:1, en donde el silicio y el boro están presentes en la mezcla en por lo menos 25% en peso, y en donde la por lo menos una fuente de boro y la por lo menos una fuente de silicio están libres de oxígeno
Patent CR-20160475-A (CR)
Title: Derivados de ácido 1-amino-2-ciclobutiletilborónico
Inventor: LI JING
IPC: C07F5/02
Filed: 2009-09-25
Abstract: La presente invención provee nuevos compuestos útiles como inhibidores de proteasoma. La invención también provee composiciones farmacéuticas que comprenden los compuestos de la invención y métodos de uso de las composiciones en el tratamiento de diversas enfermedades.
Patent CR-20180322-A (CR)
Title: Compuestos de diamina-arilsulfonamida sustituidos con hidroxialquilamina e hidroxicicloalquilamina con actividad selectiva en canales de sodio activados por voltaje
Inventor: ZHANG TING
IPC: C07D417/12
Filed: 2016-12-14
Abstract: Se divulgan compuestos de fórmula A, o una sal del mismo: Fórmula A, en la que R1, R2 y E se definen en el presente documento, compuestos que tienen propiedades para inhibir los canales de iones Nav1.7 encontrados en neuronas periféricas y simpáticas. También se describen formulaciones farmacéuticas que comprenden los compuestos de fórmula A o sus sales, y procedimientos de tratamiento de trastornos de dolor, tos, y picazón usando las mismas
Patent CR-20200183-A (CR)
Title: Btk inhibitor compounds
Inventor: HENRY KENNETH JAMES JR
IPC: C07D403/14
Filed: 2018-10-30
Abstract: The invention provides BTK Inhibitor compounds, pharmaceutically acceptable salts, pharmaceutical compositions thereof, and methods of using these compounds, salts, or compositions to treat autoimmune diseases such as Rheumatoid Arthritis.
Patent EC-SP044963-A (EC)
Title: 2-(3,5-BIS-TRIFLUORMETIL-FENIL)-N-[6-(1,1-DIOXO-1l6-TIOMORFOLIN-4-IL)-4-(2-METIL ó 4-FLUOR-2-METIL SUBSTITUIDO) FENIL-PIRIDIN-3-IL]-N-METIL-ISOBUTIRAMIDA
Inventor: POLI SONIA MARIA
IPC: A61P11/00
Filed: 2004-01-29
Abstract: La invención se refiere a los compuestos, 2-(3,5-bis-trifluormetil-fenil)-N-[6-(1,1-dioxo-1l6-tio-morfolin-4-il)-4-o-tolil-piridin-3-il]-N-metil-isobutiramida y 2-(3,5-bis-trifluormetil-fenil)-N-[6-(1,1-dioxo-1l6-tio-morfolin-4-il)-4-(4-fluor-2-metil-fenil)-piridin-3-il]-N-me-til-isobutiramida, que pueden ser de utilidad para el tratamiento de la migraña, artritis reumatoide, asma, hiperreactividad bronquial, enfermedad inflamatoria del intestino o para el tratamiento de trastornos incluyendo la enfermedad de Parkinson, ansiedad, depresión, dolor, jaqueca, enfermedad de Alzheimer, esclerosis múltiple, edema, rinitis alérgica, enfermedad de Crohn, daño ocular, enfermedades inflamatorias oculares, psicosis, enfermedad del movimiento, vómito inducido, emesis, incontinencia urinaria, trastornos psicoinmunológicos o psicosomáticos, cáncer, síntomas de abstinencia de drogas adictivas de opiáceos o nicotina, daño cerebral traumático o hiperplasia prostática benigna.
Patent EC-SP045238-A (EC)
Title: Forma de dosis oral que contiene un inhibidor de pde 4 como un ingrediente activo y polivinilpirrolidona como excipiente
Inventor: DIETRICH RANGO
IPC: A61K45/00
Filed: 2004-08-19
Abstract: Se describen formas de dosificación para administración oral de un inhibidor de PDE 4 cuya solubilidad es ligera. Contienen PVP como aglutinante.
Patent EC-SP045345-A (EC)
Title: Tratamiento de la gastroparesia
Inventor: JAKUBOWSKI JOSEPH ANTHONY
IPC: A61K38/26
Filed: 2004-10-08
Abstract: La presente invención se refiere al uso de compuestos de GLP-1 para tratar la gastroparesia. Los pacientes con gastroparesia experimentan generalmente un retraso en el vaciado gástrico. Los compuestos de GLP-1 se pueden usar para regular el vaciado gástrico en estos pacientes.
Patent EC-SP066789-A (EC)
Title: Composiciones sinérgicas
Inventor: TALBOT ROBERT ERIC
IPC: A01N57/34
Filed: 2006-08-25
Abstract: Esta invención se refiere a composiciones disolventes biocidas sinérgicas o de sulfuros metálicos.La presente invención es una invención de selección relativa a la solicitud PCT publicada WO 99/33345 del mismo solicitante.Dicho documento WO 99/33345 describe composiciones biocidas sinérgicas que comprenden "THP", un biopenetrante no tensioactivo compatible con "THP" y opcionalmente un tensioactivo.El término "THP" es definido en el documento WO 99/33345 significando o bien una sal de tetrakis(hidroxialquil)fosfonio o bien una tris(hidroxialquil)fosfina. Para evitar confusiones, se hará referencia en lo sucesivo a "sales de THP" o "THP", respectivamente.Ejemplos de biopenetrantes no tensioactivos descritos en dicho documento WO 99/33345 incluyen derivados fosfonados de ácidos carboxílicos, por ejemplo los telómeros fosfonados descritos en la solicitudes europeas publicadas EP-A-0491391 y EP-A-0861846 del mismo solicitante.
Patent EC-SP992875-A (EC)
Title: Inhibidores de la proteina /tirosina/ cinasa /de imidazopiracina sustituidas con heterociclo
Inventor: BARRISH JOEL C
IPC: C07D307/70
Filed: 1999-03-02
Abstract: Se describen nuevas imidazopirazinas sustituidas con heterociclo y sales de las mismas, composiciones farmacéuticas que contienen tales compuestos, y métodos para utilizar tales compuestos en el tratamiento de padecimientos asociados con la proteina tirosina cinasa, como desórdenes inmulológicos.
Patent FI-20001699-A (FI)
Inventor: BOURKE PETER
IPC: B03D1/16
Filed: 2000-07-21
Abstract: The invention relates to a rotor used in the flotation mechanism in the concentration of ores. According to the invention, upper part of the rotor chambers under the rotor cover are formed to be downward inclined from the outer edge of the chambers into the core so that they form an angle between 5 to 70 degrees with the horizontal plane. In addition the upper surface of the rotor cover can be inclined upwards raising from around the rotor shaft towards the outer edge at an angle between 5-70 degrees. With the means inside and above the rotor the slurry is directed upwards through the stator of the flotation mechanism. The developed rotor improves the suspension of coarse particles with high specific gravity within a flotation machine. The invention relates also to a method for inverting the material flow disharging from the rotor.
Patent FI-20045137-A (FI)
Inventor: SAIKKONEN ARI
IPC: F02M37/00
Filed: 2004-04-16
Abstract: A method of operating a gas engine, the gas engine comprising a first fuel feed system (2), a second fuel feed system (3) and a third fuel feed system (4), in which method in the first operation mode the engine is run by introducing gaseous fuel into the engine (1) combustion air via the first fuel feed system (2), and the gaseous fuel is ignited by injecting ignition fuel into the mixture of gaseous fuel and combustion air via the second fuel feed system (3). In the second operation mode of the method the engine is run by still introducing gaseous fuel into the engine (1) combustion air via the first fuel feed system (2) and the gaseous fuel is ignited by injecting ignition fuel into the mixture of gaseous fuel and the combustion air via the third fuel feed system (3).
Patent FR-1212121-A (FR)
Inventor: PORNIN HENRI
IPC: F16H59/04
Filed: 1958-07-31
Granted: 1960-03-22
Abstract: 884,233. Change-speed control; clutches. SIGURET, P., and PORNIN, H. July 29, 1959 [July 31, 1958], No. 26019/59. Class 80 (2). A transmission, particularly for a vehicle, comprises a variable-speed gear in which speed changes are initiated by positive clutches controlled by electromagnetically operated axially movable plungers serving as clutch locking or moving elements. The two-speed gear unit shown in Fig. 1 comprises input and output shafts 2, 7 with pinions 1, 6 meshing with pinions 3, 5 on a layshaft 4, and two electromagnet assemblies 10, 11 for establishing a direct drive and gear drive respectively. For direct drive coil 12 is first energized to establish synchronism between shafts 2, 7 by an armature 18 provided with recesses 21, the engagement of balls 22 with which operates electric contacts 27, 28 to energize coil 13, thereby causing axial displacement of an armature 15 and the forcing of plungers 17 into armature openings 20 to lock shafts 2, 7. Coils 12a, 13a of assembly 11 are operated in a similar manner to establish synchronism and locking of pinion 6 and shaft 7 for gear drive. The transmission shown in Fig. 2 comprises an electromagnetically operated main clutch 30, a unit with electromagnets 10, 11 operating as previously described to establish second and third gears, and a second unit with an electromagnet 37 for first gear and a sliding pinion 5b for reverse drive. In this case the locking plungers 17, 17a are integral with the axially movable armature 15. The main clutch is supplied with current from the vehicle dynamo and the magnets 10, 11, 37 from the battery, under manual or automatic control. Fig. 3 shows a manually operated switch arrangement consisting of three studs I, II, III for the respective ratios, and each provided with three contacts connected to the battery, main clutch winding 31, and the appropriate one of the magnets 10, 11, 37. In automatic arrangements, Figs. 5 and 6 (not shown), energizing of the magnets is controlled by a rotary contact arm (82) driven in accordance with engine speed. In a further transmission. Fig. 7 (not shown), the plungers (123, 124, 125) operate dog-clutch elements.
Patent GB-1006273-A (GB)
Abstract: 1,006,273. Mechanical wave couplings. COMPAGNIE GENERALE DE GEOPHYSIQUE, and INSTITUT FRANCAIS DU PETROLE DES CARBURANTS ET LUBRIFIANTS. May 7, 1963 [May 8, 1962], No. 18087/63. Heading H4J. In an electro-mechanical generator of vibrations for use in seismic prospecting, a coupling between a moving coil assembly 1 and a ground plate 4 comprises a lever 11 flexibly connected by blades 13 and 12, respectively, to an arm 5 formed integrally with plate 4 and an arm 9 attached to the coil, the lever also being pivotally connected by a blade 14 to a massive block 3 which is rigidly attached to the magnet system 2 and suspended by means of a spring 7 from the arm 5. It is stated that the coupling acts in effect as an amplitude transformer, viz. the amplitude of vibration of the plate is lower than that of the coil but the force exerted by the plate on the ground is proportionately higher. More than one coupling may be used (Fig. 2, not shown) and the block 3 may alternatively be attached to the plate 4 by means of a compression spring.
Patent GB-1015976-A (GB)
Abstract: 1,015,976. Cold-cathode tubes. PHILIPS ELECTRONIC & ASSOCIATED INDUSTRIES Ltd. Aug. 25, 1964 [Aug. 28, 1963], No. 34701/64. Heading H1D.  A cold cathode glow discharge trigger tube includes a symmetrical arrangement of a cathode, anode, trigger electrode, and primer electrode, all the electrodes being plate-shaped and supported by their supply wires, the anode and cathode being parallel to one another, and the trigger and primer electrodes at rightangles thereto and extending into slots in the cathode and the anode respectively. Cathode, anode, trigger electrode, and primer electrode, 4, 6, 8, and 10, respectively, are of molybdenum sheet, the remote surfaces of the anode and cathode being coated with nickel, and the tube being filled with argon at 100 to one together with tritium. In manufacture, the electrodes are welded to their support wires which are passed through openings in a powder glass base 1, which is simultaneously sealed to the wires and to the 6 mm. diameter tube 2 which acts as pumping tube prior to sealing off at 3, the electrode surfaces subsequently being cleaned by a discharge.
Patent GB-1051775-A (GB)
IPC: B22F9/08
Abstract: 1,051,775. Powder metallurgy. MANNESMANN A.G. Feb.26, 1964. No. 8023/64. Heading C7D. Semi finished sintered products of nickelchromium steel, such as sheets, wires or tubes are produced from water atomised steel powder which contains carbon and oxygen in stoichiometric amounts to produce carbon monoxide, the powder being compacted then vacuum sintered and finally rolled or pressed. During vacuum sintering decarbonisation and deoxidation take place by reaction of the carbon and oxygen. The carbon and oxygen content of the steel powder is adjusted by adding 0À3 - 1% of carbon to the steel melt prior to atomisation or by mixing steel powders of different carbon and oxygen content. Sintering in vacuum is effected at 1170‹C. and the sintered compact may be hot or cold rolled.
Patent GB-1052655-A (GB)
IPC: G05D1/02
Abstract: 1,052,655. Vehicle control. E. WINTER, A. WINTER, E. WAGNER, R. WAGNER, F. KEIM and L. WAGNER, [trading as ERNST WAGNER APPARATEBAU]. May 13, 1964 [May 17, 1963], No. 19881/64. Heading B7N. In an arrangement for controlling a driverless vehicle which is guided photo-electrically to follow a route defining light-reflecting strip set on the ground and which automatically halts when light reflection is interrupted, each stopping point is provided with means for offsetting a section of the strip to bring the vehicle to a halt. Each stopping point includes a plate 16 on which a part 17 of the light-reflecting guide strip 15 is disposed. The plate can be moved transversely of the strip to offset the part 17 of the guide line when it is required that the vehicle halts at the stopping point. Movement of the plate to interrupt the strip can also raise a mechanical stop element which coacts with a stop member on the vehicle to provide additional means for bringing the vehicle to a halt.
Patent GB-1225625-A (GB)
IPC: B65D25/34
Filed: 1967-06-26
Abstract: 1,225,625. Liquid containers. GRUNDY (TEDDINGTON) Ltd. 26 June, 1968 [26 June, 1967], No. 29298/67. Heading B8D. A liquid container comprises a hollow metal body 10 with end walls and an outer jacket 11 of a synthetic plastics material having a ring extending at each end beyond the end wall of the hollow body to form a rolling ring or chime 13. The jacket may be formed in two parts 11, 11a which can be extruded over the metal body. The two parts may be welded together at their inner abutting ends and each have a thickened circumferential part 12 constituting a rolling ring. The rings 13 may seat on the end wall of the hollow body, one of them serving to protect a bung hole 14 of the hollow body. The jacket may be in more than two parts and have hand-hold apertures and drain holes may be incorporated in the hollow body. Jackets may be made in different colours. The hollow body may be made of stainless steel or an aluminium alloy.
Patent GB-1225985-A (GB)
IPC: E05B65/16
Filed: 1968-02-16
Abstract: 1,225,985. Door fastenings. W. H. MINER Inc. 16 Feb., 1968, No. 7691/68. Heading E2A. Door bolting means for use with a door 22 having a vertical closing edge and adapted to be swingable about a vertical axis towards and away from a second member 20, comprises the combination of a vertically extending bar 32, a guide assembly 18 adapted to be secured to the said door so that a portion projects beyond the closing edge of said door in which portion said bar is rotatably mounted, said projecting portion of said guide assembly having an arm element 86 adapted to be engageable with said second member for aligning said door and said second member in a substantially coplanar relationship with each other when said door is swung toward said second member, vertical alignment keeper means 44 adapted to be mounted on said second member, and vertical alignment keeper engaging means 66 mounted on said bar intermediate the ends thereof. In the construction shown the means 66 is a finger element secured by welding to the bar 32 and the keeper means 44 is a generally U-shaped strap, a buffer plate 62 being secured between the strap and the surface of the member 20; upper and lower wall portions 50 and 52 of the strap are inclined so that when the finger element engages the strap it engages one or other of these inclined surfaces if the door is incorrectly aligned with the member 20 and becomes correctly aligned. Each guide assembly 68 consists of a generally U-shaped strap element 70 having a bight portion 72 and a pair of leg portions 74 and 76; a spacer element 78 is interposed between the leg portions and has an arcuate bearing surface 80 which faces the bight portion 72, the bar 32 being engaged between the bight portion and the bearing surface. As shown the member 20 is a second door and the door 22 holds this second door 20 closed; the door 22 is fastened to a door frame 10 by cam bolts 34 at each end of the bar 32 which engage keeper means 36 on the door frame. In an alternative construction however the second member is part of the door frame and in this case the cam bolts 34 and keeper members 36 are omitted; instead there are two finger elements 66 and two keeper means 44. In each construction the bar 32 is rotated by a hand lever 38 which is pivotally connected to it and which is normally retained in a sealing member 42 secured to the door when the door is in closed position.
Patent GB-1226842-A (GB)
IPC: F16C23/04
Filed: 1968-02-28
Abstract: 1,226,842. Making bearings; stamping; soldering. MINISTER OF AVIATION SUPPLY. 3 March, 1969 [28 Feb., 1968], No. 9612/68. Headings B3A, B3Q and B3R. A shell bearing member 11, for use in a split-shell spherical or part spherical bearing assembly, is formed by pressing together, in a clamping jig 14 provided with an inner portion 10, a liner 13 of bearing material and a backing member 12, there being a layer of deformable joining material between the liner and the backing member, whereby during pressing, in which the shell bearing member 11 is formed, the bearing surface of the liner 13 replicates the surface profile of the portion 10, which corresponds with the inner member of the bearing assembly in which the shell bearing member will be used. The clamping jig may comprise the housing and the inner member of the bearing assembly in which the shell bearing member will eventually be used. The member 10 is machined from steel and the members 12 from a steel socket, which is subsequently cut across. The liners 13 are of PTFE impregnated sintered bronze with a steel backing and are hand formed to the approximate shape of the member 10. The mating surfaces of the liners 13 and members 12 are coated with solder or an adhesive resin and heated while in the jig.
Patent GB-1227214-A (GB)
IPC: F16D65/54
Filed: 1968-06-07
Abstract: 1,227,214. Self adjusting brake linkage. H. O. SCHROTER. 7 June, 1968 [10 June, 1967], No. 27269/68. Heading F2E. A self adjusting linkage for use in a handbrake mechanism comprises a unidirectional ratchet device formed by a ratchet bar 1 sliding in a channel member 4 which carries a pair of pawls 2, 3, pivoted so that they are half-a-tooth out of phase and permit only contraction of the linkage. A further channel member 7 sliding on the bar 1 carries a pawl 8 attached by a tension spring 9 to the main channel 4. A bar 12 attached to the chassis at 13 passes through an abutment 11 on the channel 7 and permits limited movement between a back-stop 6 and an adjustable front-stop 5. When movement of the linkage exceeds this limit the channel 7 and pawl 8 are moved back one tooth on brake application, and the main channel member is pulled back by spring 9 on release.
Patent GB-1227711-A (GB)
IPC: G06F1/04
Filed: 1969-10-21
Abstract: 1,227,711. Data clock synchronizing circuits. INTERNATIONAL STANDARD ELECTRIC CORP. 21 Oct., 1969 [25 Oct., 1968], No. 51476/69. Heading H3A. A system for synchronizing the clocks of data processing equipments includes: means for periodically generating a synchronizing signal from a first "on-line" clock; means associated with a second "stand-by" clock for defining a time "window" within which the synchronizing signal should occur ; and means to synchronize the second clock with the first if the synchronizing signal occurs within the "window", but not if it occurs outside. The "stand-by" unit EST1  generates signals RES, LIG at a "1" level and includes a clock generator comprising an oscillator OSC and two cascaded counters HTP, HTR, various stages of which provide signals for the associated, synchronizing circuit CS. The "on-line" unit EST2, not shown in detail, comprises identical elements to EST1 but the corresponding, signals generated, RES<SP>X</SP>, LIG<SP>X</SP> are at "0" level. When the counters in EST1 reach stages TP121 and TRO, AND gate p3 opens and the next pulse th. from OSC sets bistable RZHTP to provide a "1" output which is applied to AND gate p4.. The next th pulse then sets bi-stable ASY to define the start of the synchronizing "window". The "1" signal from RZHTP is also applied via OR gate p10 to reset counter HTP to TPO. The count in HTP is thus limited to 122 in each clock cycle, although the maximum count of HTP is 127. In the "online" unit EST2 initiation of a corresponding sequence is inhibited by the "0" level LIG<SP>X</SP> signal applied to its p3 gate. Counter HTP in this unit will thus count to its full value of 127 before resetting to TPO. When the "on-line" unit's clock reaches TP126 and TRO, an AND gate, corresponding to p2 of EST1, is opened to provide a signal ESY<SP>X</SP> which is fed to AND gate p12 of EST1. If signal ESY<SP>X</SP> is received by EST1 whilst ASY is in its "1" state, i.e. during the "window", AND gate p12 is enabled to set bi-stables ERSY, MPSY and open gate pl to produce a "1" signal SYN which resets counter HTP in EST1 to TPO again. The timing of this SYN signal such that this resetting occurs as counter HTP in EST2 resets to TPO at the end of its cycle. Signal SYN also resets bi-stable ASY via OR gate p6 to terminate the "window". If no ESY<SP>X</SP> signal occurs before counter HTP in EST1 reaches TP8, the TP8 signal resets bistable ASY via OR gate p6 to terminate the "window". In this case, when the ESY<SP>X</SP> signal arrives AND gate p12 is inhibited, since ASY is in its "0" state, and AND gate p9 is enabled by the "1" ASY signal setting bi-stable FSY to produce a "no synchronization" signal. Under these conditions, the counter HTP in unit EST2 will continue to cycle counting to 127 and counter HTP in unit EST1 will continue to cycle counting to 122 until the relative counts are such that signal ESY<SP>X</SP> does fall within the "window".