baber/WOPTO huggingface dataset:
Patent NZ-562234-A (NZ)
Title: P-cadherin antibodies
Inventor: BAUER CHRISTOPHER TODD
IPC: A61K39/395
Filed: 2006-04-13
Abstract: Provided is an isolated antibody or antigen-binding portion thereof that binds to P-cadherin and comprises a VH domain and a VL domain, wherein the VH domain comprises: a) a VH CDR1, b) a VH CDR2, and c) a VH CDR3, and wherein the VL domain comprises: d) a VL CDR1, e) a VL CDR2 and f) a VL CDR3, all with specified sequences or variants differing only by 1 or 2 conservative amino acid substitutions. Further provided are corresponding nucleic acid molecules encoding said antibodies, with specified sequences.
Patent NZ-571378-A (NZ)
Title: A quarter turn tap
Inventor: ENGLAND SAM ROBERTSON
IPC: F16K3/32
Filed: 2007-03-02
Abstract: A tap (10) is disclosed. The tap includes a handle, a spindle (12), a body (18), a substantially cup-shaped elastomeric seal (26), and first (28a) and second (28b) complimentarily shaped ceramic valve members. The spindle (12) turns about its longitudinal axis when the handle is turned. The body (18) has a fluid inlet (20), a fluid outlet (22) and an opening (24) for receiving the spindle. The seal (26) has a base (26a) and a sidewall (28b). The seal base (26a) has a fluid inlet opening (38) in fluid communication with the body's fluid inlet (20) and seals around the body fluid inlet (20). The seal's sidewall (26b) has a fluid outlet opening (42) in fluid communication with the body fluid outlet (22) and seals the fluid outlet (22). The first valve member (28a) is adjacent the end of the spindle (12) which is opposite the handle. The first valve member turns in response to turning of the handle, and has at least one opening (36a). The second valve member (28b) is positioned between the first valve member (28a) and the seal base (26b), is restrained against turning relative to the seal base (26b), and has a opening (36) in fluid communication with the fluid inlet opening (38) in the seal base (26b). Moving the handle moves the first valve member (28a) between an opened position, and a closed position. In the open position the first (28a) and second (28b) valve members are aligned, which permits fluid flow from the body fluid inlet (20) to the body fluid outlet (22) via the second valve member openings (36) and the interior of the seal (26). In the closed position, the first valve member (28a) occludes the openings in the second valve member (28b) to prevent said fluid passage.
Patent NZ-573732-A (NZ)
Title: Hydroxylated and methoxylated cyclopenta [d] pyrimidines as akt protein kinase inhibitors
Inventor: MITCHELL IAN S
IPC: A61P35/00
Filed: 2007-07-05
Abstract: Disclosed are (7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazine derivatives as represented by the general formula (I) and resolved enantiomers, resolved diastereomers and salts thereof, wherein: R1 is methyl; R2, R5, Rc, Rd, R8 and R10 are hydrogen; G is an optionally substituted phenyl or 5-6 membered heteroaryl group; R6 and R7 are independently hydrogen, methoxy, substituted alkyl, or heteroaryl, or R6 and R7 together with the nitrogen to which they are attached form a 4-7 membered optionally substituted heterocyclic ring; and wherein the remaining substituents are as defined herein. Representative compounds include compounds such as (S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one. Further disclosed is a pharmaceutical composition which comprises a compound as defined above for use in the prophylactic or therapeutic treatment of hyperproliferative disorders such as cancer.
Patent NZ-574514-A (NZ)
Title: Compositions, suitable for oral administration, comprising a triazolo [4, 5-d]pyrimidin derivate
Inventor: BANKS SIMON
IPC: A61P37/02
Filed: 2007-08-20
Abstract: Discloses a pharmaceutical composition comprising: { 1 S-[1 0, 20, 313 (1 S*,2R*),513]} -3-(7 -{ [2-(3,4-difluorophenyl)cyclopropyl]amino} -5-(propylthio )-3H-1 ,2,3-triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol, a filler of the general structure (I) in the drawing which is a mixture of mannitol and dibasic calcium phosphate dehydrate, a binder which is hydroxypropyl cellulose, disintegrant which is sodium starch glycollate and one or more lubricants. The pharmaceutical composition disclosed has a therapeutic application in the treatment of thrombosis associated conditions.
Patent NZ-582060-A (NZ)
Title: A high pressure water jet cleaner with removable reservoir
Inventor: TURNER JOHN CHARLES
IPC: B05B1/02
Filed: 2009-12-17
Abstract: A high pressure water jet cleaning system, for domestic use, is disclosed. The cleaning system comprises a cleaner body assembly, a removable water reservoir sitting on or within the cleaner body assembly, a high pressure pump housed within the cleaner body assembly, a 3-way valve within the cleaner body assembly, and a fluid coupling system between the water reservoir and the 3 way valve. The 3-way valve within the cleaner body assembly is in fluid connection with a first port to the inlet of the high pressure pump, a second port to the removable water reservoir, and a third port to an external water supply connection point on the cleaner body assembly. The fluid coupling system is located between the water reservoir and the 3 way valve. This allows the water reservoir to be removed from, and reinstalled on or within, the cleaner body assembly quickly and conveniently without the use of tools and without having to carry out a separate action to connect/disconnect the fluid coupling. Therefore, no significant water leakage or air is able to enter the water supply line to the high pressure pump. In operation the high pressure pump draws water either from the water reservoir through the fluid coupling system and the 3 way valve or from the external water supply connection point through the 3 way valve.
Patent NZ-585656-A (NZ)
Title: Allowing a user to join a multiplayer online game and switching them to another server
Inventor: PERLMAN STEPHEN G
IPC: H04W4/00
Filed: 2008-12-04
Abstract: Disclosed is a method of joining a user to an interactive video game. The method includes interacting with a user via first streaming interactive video (1529) originating from a first server (1521) of a hosting service centre (210) and compressed in a compression unit (1530). The user interacts via a client device remote from the hosting service centre (210). The method also includes transitioning the user from the first server (1521) to a second server (1522) that generates second streaming interactive video (1529). The second streaming interactive video (1529) is provided to the client device of the user via the compression unit (1530). To the user, the transitioning from the first server (1521) to the second server (1522) appears perceptually instantaneous.
Patent NZ-587248-A (NZ)
Title: Sewage tanks and grinder pump systems
Inventor: DALEY PAUL
IPC: E02D29/12
Filed: 2005-08-01
Abstract: Disclosed is a sewage tank (20) for use with a pump to convey sewage. The tank comprises a container, which has an upper portion (24) and a lower tapering portion (22) defining a chamber (30), the lower tapering portion having a reduced size compared to the upper portion. The lower portion comprises an outwardly extending member (40) which is spaced below a bottom of the upper portion, spaced below a portion of the lower tapering portion, and is disposed adjacent to a bottom of the lower tapering portion. The lower tapering portion and the outwardly extending member are configured to allow backfilling of material in an area between an upper surface of the member and an outside surface of the lower portion, so that backfill provides sufficient ballast under high ground water conditions.
Patent NZ-590707-A (NZ)
Title: A multi-heat source power plant
Inventor: SINAI JOSEPH
IPC: F03G6/00
Filed: 2009-06-29
Abstract: 590707 A method and apparatus for efficiently operating a multi-heat source power plant using geothermal fluid is disclosed. The method includes pre-heating (2) an organic motive fluid (5) using a geothermal liquid or brine (1) to a temperature less than the boiling temperature of the fluid. Further heat is provided from a concentrated solar energy source (6) to boil the fluid without input of heat from the geothermal liquid or brine (1) to produce organic motive fluid vapour (5'') at a substantially constant temperature. The vapour (5") is then supplied to a vapour turbine (7) for expansion.
Patent NZ-592745-A (NZ)
Title: Scaffold system pivotably connected with l-shaped transom bars to support platform boards
Inventor: KANG JOSEPH SAM
IPC: E04G1/34
Filed: 2009-11-04
Abstract: A scaffold system is disclosed comprising a first main frame (22) with a first pair of generally parallel posts (24, 26) and a first ledger rail (28) extending between and perpendicular to the first pair of posts. An upper end of each post has a male engagement formation (70) which is engageable with a female engagement formation formed in a lower end of a corresponding post to interconnect the posts end to end. A second main frame (30) has a second pair of generally parallel posts and a second ledger rail extending between and perpendicular to the second pair of posts. First and second transom bars (50) extend between the first pair of posts (24, 26) and the second pair of posts. The first and second transom bars (50) have a generally L-shaped profile adapted to receive and support one or more platform boards (100) and are pivotally connected to the posts with collars.
Patent NZ-593221-A (NZ)
Title: Detecting and monitoring left ventricular hypertrophy and congestive heart failure by profiling biomarkers
Inventor: SPINALE FRANCIS G
IPC: G01N33/48
Filed: 2009-11-04
Abstract: Provided is a method comprising measuring the amount of three or more biomarkers in a body fluid sample from a subject, wherein the amount of three or more of the three or more biomarkers compared to a reference amount for the biomarker indicates the presence or risk of diastolic heart failure in the subject, wherein the three or more biomarkers include MMP-2, MMP-8 and TIMP-4. Further provided are specific thresholds for diagnosis and additional markers to be used in conjunction with the three markers.
Patent NZ-593445-A (NZ)
Title: A method and apparatus for determining a mixing regime for use in the preparation of animal feed from a set of ingredients, and a system for producing the animal feed
Inventor: PENFARE TIMOTHY JOHN
IPC: A23K1/18
Filed: 2009-12-03
Abstract: 593445 Disclosed is an apparatus (5) for determining a mixing regime under which ingredients of a set of ingredients are to be mixed in the preparation of animal feed. The apparatus (5) has a main computer (15) configured to store a master table comprising a list of ingredients or categories of ingredients suitable for use in the preparation of animal feeds. This list is cross-referenced with corresponding standard mixing periods. At least one mixing factor is stored for at least some of the ingredients of the master table cross-referenced with the corresponding ingredient. Each mixing factor is adapted to be applied to the standard mixing period of the corresponding ingredient for altering the standard mixing period thereof. This is in response to a non-standard condition being identified in a set of ingredients for which a mixing regime is to be determined. The ingredients are then read from the set of ingredients and standard mixing periods are obtained for at least some of the ingredients of the set of ingredients from the master table. Any non-standard conditions are identified from the set of ingredients, and a mixing factor is obtained from the stored mixing factors for one of the ingredients to compensate for an identified non-standard condition in response to an identified non-standard condition. The mixing periods are obtained for at least some of the ingredients of the set of ingredients to which those ingredients are to be subjected during a mixing cycle of the mixing regime as a function of the corresponding standard mixing periods and any corresponding mixing factors. A loading sequence of the mixing regime is then produced in which the ingredients of the set of ingredients are to be loaded into the mixing apparatus (5) during the mixing cycle for mixing thereof to produce the animal feed. This is done so that the ingredients for which mixing periods are determined are subjected to mixing for the respective corresponding determined mixing periods during mixing of the set of ingredients under the mixing regime.
Patent NZ-594029-A (NZ)
Title: Cna_b domain antigens in vaccines against gram positive bacteria
Inventor: GRANDI GUIDO
IPC: A61K39/02
Filed: 2010-01-12
Abstract: 594029 Disclosed is an isolated Cna_B domain antigen capable of inducing or increasing an immune response to one or more gram-positive bacteria. Also disclosed is a fusion polypeptide comprising said antigen and a further bacterial antigen, a nucleic acid encoding said antigen, a non-human host cell that comprises an expression vector that encodes said antigen, and an isolated antibody that selectively binds to said antigen. Further disclosed is a method for producing said antigen and a method for reducing infection in a non-human patient by a gram-positive bacterium comprising administering said antigen.
Patent NZ-595193-A (NZ)
Title: Modified Proteases That Inhibit Complement Activation
Inventor: MADISON EDWIN L
IPC: A61K38/48
Filed: 2006-10-20
Abstract: Patent No. 595193 Disclosed is the use of a modified non-complement protease, or a catalytically active portion thereof, for formulation of a medicament for inhibiting complement activation to effect treatment of an inflammatory disease or disorder, wherein: the non-complement protease, or catalytically active portion thereof, comprises modifications at an amino acid residue that is a determinant of specificity compared to an unmodified or scaffold protease; the scaffold protease is an MT-SP1 protease or a catalytically active portion thereof; the modified amino acid residue(s) increases one or both of specificity for a target substrate or activity towards a target substrate, wherein the target substrate is a complement protein; and the non-complement protease, or a catalytically active portion thereof, when contacted with any one or more target substrates of a complement pathway, results in cleavage of the target substrate protein such that complement activation in a pathway comprising the target substrate is inhibited, whereby inhibition of complement activation leads to a reduction of inflammatory symptoms associated with the disease or disorder, thereby treating the disease or disorder .
Patent NZ-597123-A (NZ)
Title: A farm fence gate hinged horizontally at ground level and retained vertically by springs that lies flat as the gate is driven over
Inventor: MACDONALD PHILLIP CHARLES
IPC: E05F13/00
Filed: 2011-12-15
Abstract: An improved ride-over gate assembly (1) which may enable a vehicle to push the gate (2) down and to drive over it wherein the gate rises to an upright position when the vehicle moves off the gate. The ride-over gate assembly includes a gate, a rocker base (18), a rocker arm (9), and a resilient device connected between a first connector (32) and a second connector (33). The gate has a frame (3), made up of a first side (4), a second side (5), a gate top (6), a gate base (7) and includes horizontal bars (8). The rocker base is attached with respect to the surface on which the gate assembly is located. The rocker arm is attached to the side edge of the gate in the vicinity of the gate base and is located adjacent to the rocker base. The first connector is located on the side of the gate, and the second connector is located on the rocker base such that the resilient device extends substantially parallel to the side of the gate. In one embodiment the resilient device includes a spring (30) that returns the gate to its normal upright position once it has been driven over.
Patent NZ-597589-A (NZ)
Title: Spirocyclic amide derivatives
Inventor: KINDON NICHOLAS
IPC: A61K31/5386
Filed: 2010-07-29
Abstract: Patent No. 597589 Disclosed are N-Butyl-N-(2-(2-(5-hydroxy-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-8-yl)ethylamino)ethyl)-3-(3-(2-(4-(2-isopropylthiazole-4-carbonyl)-1-oxa-4,9-diazaspiro[5.5]undecan-9-yl)ethyl)phenethoxy)propanamide and N-Cyclopentyl-N-(2-(2-(5-hydroxy-3-oxo-3,4-dihydro-2H -benzo[b][1,4]oxazin-8-yl)ethylamino)ethyl)-3-(3-(2-(4-(2-isopropylthiazole-4-carbonyl)-1-oxa-4,9-diazaspiro[5.5]undecan-9-yl)ethyl)phenethoxy)propanamide ditrifluoroacetate.
Patent NZ-601424-A (NZ)
Title: Method for the production of ad26 adenoviral vectors
Inventor: LUITJENS ALFRED
IPC: C12N15/861
Filed: 2011-02-14
Abstract: Discloses a method for producing recombinant adenovirus serotype 26 (rAd26), the method comprising: a) culturing PER.C6 cells as per ECACC deposit 96022940 in a suspension with a perfusion system; b) infecting said cells at a density of between 10x10^6 viable cells/ml and 16x10^6 viable cells/ml with rAd26 c) further culturing the infected cells with a perfusion system to propagate said rAd26 and d) harvesting said rAd26
Patent NZ-606107-A (NZ)
Title: A method for providing a textile product, the product itself and uses thereof
Inventor: REUTELINGSPERGER CHRISTIAAN MATHIAS HUBERTUS GERAR
IPC: D06N7/00
Filed: 2011-06-29
Abstract: The disclosure relates to a method for providing a textile product such as a carpet comprising providing yarns, contacting the yarns that comprise keratin fibres with a support material that comprises cellulose fibres of natural origin to form an intermediate product and bonding the yarns to the support material to form the textile product, wherein the bonding takes place by an in-situ enzymatic polymerization process by applying the lignin at a site where the yarns contact the support material, followed by enzymatically converting the lignin into a binder that bonds the yarns to the support, wherein the enzyme is an oxidoreductase, preferably laccase.
Patent NZ-606782-A (NZ)
Title: Biometric reaction time system and method
Inventor: KELLY MYLES GRAHAM
IPC: B24B7/00
Filed: 2012-12-20
Abstract: A plate locking mechanism (50) for a surface preparation device comprising a connecting plate (30) having a receiving aperture, a base plate (51) and a floating plate (60) capable of: being substantially aligned with the base plate. A fastener extends through a floating plate aperture and engages with a base plate aperture (52) and a resilient member is operatively associated with the fastener to maintain the floating plate in contact with the base plate. When the base plate is located within the receiving aperture (31) of the connecting plate, the floating plate is rotatable to retain the connecting plate in position.
Patent NZ-610906-A (NZ)
Title: Improved complexes and compositions containing curcumin
Inventor: CAVE HAROLD GORDON
IPC: A61K31/661
Filed: 2012-05-22
Abstract: 610906 A complex including a phospholipid and curcumin, characterised in that the phospholipid is sourced from a marine oil. Marine oils are high in omega-3 fatty acids. Also disclosed are compositions comprising the complex and a method for preparing the complex.
Patent NZ-617165-A (NZ)
Title: Avian-based treatment
Inventor: CHAMBERLAIN JOHN
IPC: A61K35/57
Filed: 2012-05-02
Abstract: The disclosure relates to a the use of a composition comprising avian extract EP-2 in a therapeutically effective concentration together with a pharmaceutically acceptable carrier and/or diluent for treating or preventing proliferative skin disorders, cancers or pre-cancers. The avian extract EP-2 may be isolated from the tail feathers a bird of the order Psittaciformes (parrot), such as sulphur-crested cockatoo (Cacatua galerita), the galah (Cacatua roseicapilla), the Major Mitchell cockatoo (Cacatua leadbeateri leadbeateri) using an organic solvent. The proliferative skin disorder may be eczema (including atopic eczema, allergic contact dermatitis, infantile seborrhoeic eczema, adult seborrhoeic eczema, varicose eczema and discoid eczema), psoriasis (including chronic plaque syndrome, pustular psoriasis, erythrodermic psoriasis or nail psoriasis), and scarring including keloid scarring. The cancer or pre-cancer may be skin cancer (including basal cell carcinoma, squamous carcinoma or melanoma); precancerous skin lesion (such as actinic or solar keratosis); carcinomas (including breast, prostate. lung, pancreatic and colon cancers), sarcoma, lymphoma, germ cell tumour, blastoma, and leukaemia. The disclosure also relates to the use of a synthetic form of EP-2, comprising two or more of nicotinamide, 2,4-ditert butyl phenol, palmitic acid, oleic acid and squalene, for treating or preventing proliferative skin disorders, cancers or pre-cancers.
Patent NZ-617467-A (NZ)
Title: Herbicidal composition comprising flazasulfuron and an inhibitor of protoporphyrinogen oxidase
Inventor: YAMADA RYU
IPC: A01P13/00
Filed: 2012-04-06
Abstract: Provided are herbicidal compositions comprising flazasulfuron and an inhibitor of protoporphyrinogen oxidase selected from a phenylpyrazole compound, a triazolinone compound, a N-phenylphthalimide compound, a pyrimidindione compound, an oxadiazole compound, an oxazolidinedione compound, a thiadiazole compound, pyraclonil, profluazol, flufenpyr-ethyl and their salts. Exemplified compositions include flazasulfuron in combination with pyraflufen-ethyl, cafentrazone-ethyl, saflufenacil, oxadiargyl, flumioxazin, sulfentrazone, pyraclonil, pentoxazone, fluthiacet-methyl, flufenpyr-ethyl and butafenacil.
Patent NZ-618790-A (NZ)
Title: Treatment of coagulation disease by administration of recombinant vwf
Inventor: SCHEIFLINGER FRIEDRICH
IPC: A61P7/04
Filed: 2012-06-11
Abstract: Disclosed is a use of recombinant Von Willebrand Factor (rVWF) in the manufacture of a medicament for treating Von Willebrand Disease or Hemophilia A in a subject in need thereof, wherein the rVWF is a high molecular weight VWF multimer composition in which at least 20% of the total VWF multimer molecules in the composition are VWF decamers or higher order multimers, and wherein the rVWT has a higher specific activity than plasma derived Von Willebrand Factor.
Patent NZ-624707-A (NZ)
Title: Netting material with eyelets
Inventor: JONATHAN DALLAS TOYE
IPC: A01G13/10
Filed: 2013-05-08
Abstract: A netting material (see 10, figure 9A), such as that for bird netting, insect netting, shade netting, wind screen netting, or hail protection netting, is disclosed. The netting material is longer than it is wide and is formed by threads knitted or woven together. The netting material comprises a main portion (see 11, figure 9A) having knitted or woven apertures, a reinforced edge portion (21) at, or adjacent, each longitudinal edge of the netting material and having a longitudinal row of knitted or woven fastening features, and a reinforced intermediate portion (31) between the reinforced edge portions. The reinforced intermediate portion comprises a first longitudinal row (see 35A, figure 9A) of knitted or woven fastening features and a second longitudinal row (see 35B, figure 9A) of knitted or woven fastening features. The first and second longitudinal rows are spaced apart side-by-side in a lateral direction of the netting so that, in use, folding the reinforced intermediate portion of the netting along a longitudinal fold line between the first and second longitudinal rows brings the first and second longitudinal rows together to form a double layered row (36) of fastening features. The row of fastening features of the reinforced edge portions are provided with three longitudinal attachment locations for securing the netting material to a support structure.
Patent NZ-700833-A (NZ)
Title: Methods of producing anamorelin hydrochloride having controlled chloride content
Inventor: GARCIA RUBIO SILVINA
IPC: C07D401/06
Filed: 2013-04-18
Abstract: The present invention relates to particulate forms of anamorelin monohydrochloride or a composition comprising anamorelin monohydrochloride having controlled chloride content, preferably isolated in an amorphous and/or fine particulate state, processes for making the particulate forms, and pharmaceutical compositions comprising the particulate forms.