baber/WOPTO huggingface dataset:
Patent CA-3021828-A1 (CA)
Inventor: KUWAHARA ATSUSHI
IPC: A61L27/38
Filed: 2017-04-21
Abstract: L'invention concerne un procédé de production de cellules associées à la rétine ou d'un tissu rétinien, ce procédé comprenant les étapes (1) à (3) : (1) une première étape consistant à cultiver des cellules souches pluripotentes, en l'absence de cellules nourricières quelconques, dans un milieu de culture contenant 1) un inhibiteur du mécanisme d'action de signalisation de la famille TGFß et/ou un agoniste du mécanisme d'action de signalisation de Sonic Hedgehog et 2) un facteur de maintien d'état non différencié ; (2) une deuxième étape consistant à cultiver en suspension les cellules, lesquelles sont obtenues dans la première étape, dans un milieu de culture contenant un inhibiteur du mécanisme d'action de signalisation des protéines Wnt, de manière à former des agrégats de cellules ; et (3) une troisième étape consistant à cultiver en suspension les agrégats, lesquels sont obtenus dans la deuxième étape, en présence ou en l'absence de l'inhibiteur du mécanisme d'action de signalisation des protéines Wnt, dans un milieu de culture contenant un agoniste du mécanisme d'action de signalisation des protéines BMP, de manière à obtenir des agrégats contenant des cellules associées à la rétine ou un tissu rétinien.
Patent CA-3022554-A1 (CA)
Inventor: AHUJA SANJEEV
IPC: A61K39/02
Filed: 2017-05-09
Abstract: La présente invention concerne des procédés pour tester la présence et/ou l'activité de composants du système du glutathion et de composants du système de la thiorédoxine pendant le processus de fabrication de protéines contenant des liaisons disulfure. La présente invention concerne en outre des procédés pour diminuer la réduction de liaisons disulfure pendant le processus de fabrication, et pour abaisser le potentiel de réduction de protéines contenant des liaisons disulfure. L'invention concerne des compositions, des kits et des procédés pour diminuer la réduction et diminuer le potentiel de réduction de protéines contenant des liaisons disulfure pendant des processus de fabrication de protéines.
Patent CA-3022902-A1 (CA)
Inventor: PARK JAE HYUN
IPC: A61B17/32
Filed: 2017-05-15
Abstract: According to one embodiment of the present invention, provided is a handpiece punching needle used for separating, from the skin tissue of a patient, the follicle of hair to be extracted, while the punching needle rotates. The punching needle according to one embodiment of the present invention has a slit part at one side of a front end portion thereof, the slit part is formed to extend rearwards from the front end portion of the punching needle along the longitudinal direction of the punching needle, and the punching needle can be formed such that the punching needle is mounted on and used in a handpiece so as to allow a portion or all of the slit part to be exposed to the front of the handpiece. According to one embodiment of the present invention, the punching needle enables the inside of the punching needle to be directly and visually checked through the slit part formed on the punching needle, and can be formed such that the hair to be extracted can be inserted into the punching needle from a lateral side thereof through the slit part formed on the punching needle.
Patent CA-3024426-A1 (CA)
Inventor: HARRINGTON ERIK
IPC: B64C13/28
Filed: 2018-11-15
Abstract: A secondary flight control system is provided. The secondary flight control system comprising: a first flight control surface system; a second flight control surface system; and a power distribution unit operably connected to the first flight control surface system and the second flight control surface system, wherein the power distribution unit is configured to generate torque to actuate the first flight control surface system and the second flight control surface system.
Patent CA-3024479-A1 (CA)
Inventor: BLACKWELL WILLIAM
IPC: A61K38/26
Filed: 2017-05-15
Abstract: L'invention concerne des polypeptides isolés qui sont des analogues sélectifs du récepteur du glucagon et des dérivés peptidiques correspondants. Ces analogues sont sélectifs du récepteur du glucagon humain avec une solubilité, une stabilité thermique et des propriétés physicochimiques améliorées par rapport au glucagon endogène natif. La présente invention concerne également des méthodes d'utilisation de tels polypeptides dans une large gamme d'indications thérapeutiques et diagnostiques, ainsi que des procédés de production de tels polypeptides. Ces analogues sont utiles, seuls ou en combinaison avec d'autres peptides thérapeutiques, dans des méthodes de traitement de l'obésité, du diabète, de troubles métaboliques et d'autres troubles ou maladies.
Patent CA-3025780-A1 (CA)
Inventor: CHAMPAGNE MAXIME
IPC: G05D23/19
Filed: 2018-11-29
Abstract: The present disclosure provides a control circuit to control power to a load, a typically load being a heating element. The control circuit is preferably comprised of a switch, such as a TRIAC switch, to switch from a first state to a second state. An energy bank, such as a capacitor, is also provided, the energy bank to store energy to power a thermostat when the switch is in a non-conducting state. The control circuit is also comprised of a drive circuit to actuate the switch back and forth from the first state to the second state. The improved control circuit has been shown to have reduced conducted electromagnetic interference, which is advantageous to meet ever stricter government guidelines for circuitry conducted EMI.
Patent CA-3026104-A1 (CA)
Title: Spouted sachet
Inventor: GROSS-JOHNSTON CALLIE
IPC: B65D35/28
Filed: 2018-11-30
Abstract: Described herein are a packaged food product and methods of making and using the packaged food product. In some embodiments, the packaged food product comprises a spouted sachet or packet containing one or more flowable food products, such as ketchup or other condiments.
Patent CA-3029799-A1 (CA)
Title: Fermeture dotee d'une bande inviolable
Inventor: TAMARINDO STEFANO
IPC: B65D55/02
Filed: 2017-07-20
Abstract: L'invention concerne une fermeture (8) dotée d'une bande inviolable (40), comprenant une bande fixe (42, 142) et un corps mobile (50). La bande fixe (42, 142), avec la bande inviolable intacte, est attachée au corps mobile (50) au moyen d'une portion affaiblie (52, 152). La bande inviolable (40) comprend en outre un anneau inviolable (70, 170) logé, avec la bande inviolable intacte, dans un compartiment intérieur de la fermeture (8) afin d'être caché de la vue. La portion affaiblie (52, 152) se déchire en raison du dévissage de la fermeture (8) et l'anneau inviolable (70, 170) est éjecté hors du compartiment intérieur et se place lui-même, avec le joint d'étanchéité brisé, de façon à séparer un bord fixe (49, 149) de la bande fixe (42, 142) d'un bord mobile (51, 151) du corps mobile (50).
Patent CA-3031702-A1 (CA)
Title: Complexes de penetration cellulaire immolateurs pour l'administration d'acides nucleiques
Inventor: LEVY RONALD
IPC: A61K31/496
Filed: 2017-07-27
Abstract: L'invention concerne, entre autres, des complexes, des compositions et des procédés pour l'administration d'agents thérapeutiques, diagnostiques et d'imagerie, notamment un acide nucléique, dans une cellule. Les complexes, compositions et procédés peuvent permettre la complexation, la protection, l'administration et la libération d'oligonucléotides et de protéines cargo polyanioniques dans des cellules, des tissus et des organes cibles à la fois in vitro et in vivo.
Patent CA-3041543-A1 (CA)
Title: Structure de soutien aux produits du tabac
Inventor: RICHARDSON STEVEN ELLIS
IPC: A24F9/14
Filed: 2019-04-26
Abstract: Il est décrit un appareil servant à supporter des produits de fumage et des cendres dans une pipe afin de prévenir que ces derniers sintroduisent dans une chambre interne de la pipe à partir du fourneau de pipe. Une surface supérieure supporte les produits de fumage et les cendres et prévient quils se rendent plus loin que le fourneau. Des conduites placées à des endroits stratégiques dans la surface supérieure permettent à la fumée de passer, bloquent les cendres et les produits de fumage partiellement brûlés. Une structure de support retient la surface supérieure pendant lutilisation et le nettoyage.
Patent CA-3042945-A1 (CA)
Title: Compositions and methods of treating cancer
Inventor: AVIGAN DAVID
IPC: A61K39/00
Filed: 2017-11-14
Abstract: The present invention provides compositions and methods for treating cancer, wherein the composition comprises: a. a population a cells comprising a dendritic cell/tumor cell fusion or a dendritic cell/extracellular vesicle fusion; and b. an indoleamine-2,3-dioxygenase (IDO) inhibitor and/or a hypomethylating agent (HMA).
Patent CA-3044065-A1 (CA)
Inventor: SAVEYN PIETER JAN MARIA
IPC: C11D3/382
Filed: 2017-12-07
Abstract: La présente invention concerne des compositions d'adoucissant pour tissus ainsi que leurs procédés de fabrication et d'utilisation. Lesdites compositions d'adoucissant pour tissus liquides comprennent un actif adoucissant pour tissus d'ester d'ammonium quaternaire, des fibres de cellulose et un tensioactif non ionique. Lesdites compositions d'adoucissant pour tissus présentent une stabilité améliorée au gel-dégel tout en offrant également les avantages d'adoucissement recherchés par les consommateurs.
Patent CA-3044760-A1 (CA)
Inventor: FOSTER ROY A
IPC: E01F13/00
Filed: 2019-05-30
Abstract: A temporary barrier system that is configured to be placed adjacent a concrete divider on a roadway wherein the temporary barrier system provides an increased vertical barrier so as to inhibit seeing therepast. The temporary barrier system includes a storage container having the body of the present invention stored in its first position therein. The body of the present invention is planar in manner and stored in a rolled position in the storage container. The body is wrapped around a winding apparatus and includes an end that is configured to be secured to a deployment vehicle. The deployment vehicle traverses away from the storage container to deploy the body to its second position. The body further includes a plurality of support members being configured to be perpendicular to the upper and lower edge. The storage container is configured as a towable trailer.
Patent CA-3045445-A1 (CA)
Inventor: GUO JIANXIN
IPC: A61B17/068
Filed: 2017-11-13
Abstract: An applicator instrument for dispensing surgical fasteners includes an elongated shaft, a housing connected with the elongated shaft, a trigger, a gear train, and a firing system disposed in the housing. The trigger is squeezed for commencing a firing cycle. The firing system includes a storage reel, a spool connected to the storage reel, a drive wheel located distal to the storage reel and the spool, a constant torque spring having a proximal end connected to the spool and a distal end connected to the drive wheel, and a flexible member in contact with the drive wheel. The flexible member has a proximal end connected to the storage reel and a length configured to be driven by the drive wheel toward the distal end of the elongated shaft. During an energy storing stage, the gear train is coupled with the storage reel for rotating the storage reel in a counterclockwise direction, which, in turn, retracts and winds the flexible member onto the storage reel, which rotates the drive wheel in a counterclockwise direction and winds the constant torque spring from the spool onto the drive wheel for storing energy in the constant torque spring.
Patent CA-3047320-A1 (CA)
Inventor: CHAWLA LAKHMIR
IPC: A61K38/10
Filed: 2017-12-19
Abstract: The present disclosure relates to the use of hepcidin in therapeutic methods for the treatment of various conditions in which decreasing serum iron concentration may be beneficial.
Patent CA-3048323-A1 (CA)
Title: Incubation device and system comprising incubation device and rocking platform
Inventor: KAFFKA CHRISTIAN
IPC: G01N1/31
Filed: 2018-09-21
Abstract: Proposed is an incubation device comprising multiple rocking platforms which are each pivotally mounted about a respective axis, each rocking platform having a respective receiving device for mechanically reversibly receiving a respective incubation channel, also comprising a common drive unit for causing common respective rocking movements of each rocking platform from a zero position through a specific angle range as a result of a drive movement of the drive unit, each of the respective rocking platforms being coupled to the drive unit via a respective coupling mechanism, and each of the respective coupling mechanisms elastically resiliently coupling the respective rocking platform to the drive unit, such that when the rocking platform is restrained, despite continuation of the drive movement, the rocking platform remains motionless in a fixed position, but then however, after release of the restraint on the rocking platform, the rocking platform resumes the rocking movement through the specific angle range as a result of the drive movement.
Patent CA-3050232-A1 (CA)
Title: Ceiling system and hanger for suspending ceiling tiles or panels therefrom
Inventor: COOK ANDREW
IPC: E04B9/18
Filed: 2019-07-19
Abstract: A hanger for suspending tiles or panels from a ceiling or roof, and a ceiling system incorporating the hanger, is provided. The hanger comprises a suspension member securable to the ceiling, having a longitudinal axis, and a panel mount coupled to the suspension member and releasably securable to each of a multiple panels to hold the multiple panels in a spaced relation from the ceiling on a common plane.
Patent CA-3050276-A1 (CA)
Title: Structural bonding composite
Inventor: GAGNE BRIAN M
IPC: E06B3/62
Filed: 2018-01-18
Abstract: A structural bonding composite includes a polymeric base member, a first structural adhesive layer on a first side of the base member, a second structural adhesive layer on a second side of the base member opposite the first side, and a reinforcement member secured to a portion of the base member to maintain a predetermined thickness of the base member against compression applied to the first and second sides of the base member.
Patent CA-3051852-A1 (CA)
Inventor: CHO DO-YEON
IPC: A61B17/24
Filed: 2018-01-26
Abstract: L'invention concerne divers modes de réalisation pour l'administration prolongée de médicaments à l'aide d'un réseau d'aiguilles. L'invention concerne également un instrument médical et un procédé associé à celui-ci pour administrer des médicaments dans des tissus tonsillaires et d'autres tissus en tant que moyen de traitement de l'hypertrophie ou de l'inflammation tonsillaire, comme alternative aux procédures de tonsillectomie et d'adénoïdectomie. Dans certains modes de réalisation, l'invention concerne un instrument médical accessible par l'amygdale comprenant une tête d'aiguille ayant des aiguilles, ou des micro-aiguilles, disposées à l'intérieur de celle-ci et pouvant introduire un composé, tel qu'un stéroïde, dans un tissu. Les instruments médicaux permettent l'administration de divers composés, tels que des produits pharmaceutiques, pour une libération contrôlée et prolongée.
Patent CA-3053093-A1 (CA)
Inventor: TAKADA KATSUNORI
IPC: C01B32/162
Filed: 2018-03-01
Abstract: L'invention concerne un nanotube de carbone qui a au moins un défaut cristallin dans une région entre une extrémité et son autre extrémité comme observé dans la direction d'un axe qui s'étend dans une direction, le défaut cristallin ayant une propriété telle que le rapport de l'intensité IG d'un pic apparaissant dans la bande G qui est un pic provenant d'une structure de graphite apparaissant autour d'une longueur d'onde de 1 580 cm-1 sur l'intensité ID d'un pic apparaissant dans une bande D qui est un pic provenant d'un défaut apparaissant autour d'une longueur d'onde de 1 360 cm-1 (c'est-à-dire, G/D) est de 0,1 à 0,5 dans des spectres Raman obtenus à une longueur d'onde d'excitation de 632,8 nm.
Patent CA-3055014-A1 (CA)
Title: Trocar support
Inventor: PACAK JOHN S
IPC: A61B17/34
Filed: 2016-11-17
Abstract: A support apparatus for supporting a trocar while the trocar extends through a body wall of a patient includes an inflatable collar and a slidable abutment collar commonly connected for engagement onto the trocar following which the slide collar is released to slide along the trocar. The inflatable collar is inflated to a set size by a manually operable pump on the slidable collar operated by squeezing finger abutments together up to a latch so that threaded portion expels the inflation fluid. The abutment member is shaped to be received on an outer surface of the trocar and adjustable longitudinally of the trocar sleeve so as to be located at a selected position by a manually movable latch collar. The inflatable collar and slidably collar are held connected by a manually operable release.
Patent CA-3055314-A1 (CA)
Inventor: RIOS ROGELIO
IPC: E21B19/20
Filed: 2018-02-07
Abstract: A tubular transfer system (100) comprising a boom structure (110) having a first frame telescopically coupled to a second frame. A first actuator is configured to extend and retract the first frame relative to the second frame. A clamp mechanism (120) is coupled to the first frame and configured to grip and lift a tubular (10). A second actuator is configured to raise and lower the clamp mechanism (120) relative to the first frame. A tubular transfer system (100) comprising a boom structure (110) having a first frame telescopically coupled to a second frame. A first actuator is configured to extend and retract the first frame relative to the second frame. A clamp mechanism (120) is coupled to the first frame and configured to grip and lift a tubular (10). A second actuator is configured to raise and lower the clamp mechanism (120) relative to the first frame.
Patent CA-3056683-A1 (CA)
Title: Live ink presence for real-time collaboration
Inventor: RODRIGUES MAVIS NATASHA
IPC: G06F17/24
Filed: 2018-04-05
Abstract: A live ink presence indicator is provided to identify what users created what content when multiple users do real-time collaboration within an application using digital ink. A presence manager determines a presence region for a user and a suggested location for rendering a presence indicator.
Patent CA-3056922-A1 (CA)
Title: Systems and methods for processing objects, including automated radial processing stations
Inventor: WAGNER THOMAS
IPC: B65G1/137
Filed: 2018-03-22
Abstract: A method of processing objects using a programmable motion device is disclosed. The method includes the steps of perceiving identifying indicia representative of an identity of a plurality of objects and directing the plurality of objects toward an input area from at least one input conveyance system, acquiring an object from the plurality of objects at the input area using an end effector of the programmable motion device, and moving the acquired object toward an identified processing location using the programmable motion device, said identified processing location being associated with the identifying indicia and said identified processing location being provided as one of a plurality of processing locations that are radially spaced from the programmable motion device.
Patent CA-3057365-A1 (CA)
Inventor: NELSON JOSEPH
IPC: B65F3/04
Filed: 2019-10-02
Abstract: A grabber assembly includes a carriage, an adapter assembly, and a grabber arm. The adapter assembly is coupled to the carriage and includes a pin, a first member, a second member, and a sleeve. The first member is configured to receive a first end of the pin and removably fixedly couple with the first end of the pin. The second member is configured to receive a second end of the pin and removably fixedly couple with the second end of the pin. The sleeve extends co-cylindrically with the pin. The grabber arm includes a bushing. The bushing is fixedly coupled with the grabber arm and is pivotally coupled to the pin. The sleeve is positioned within a central bore of the bushing, between the bushing and the pin.
Patent CA-3059637-A1 (CA)
Inventor: BAKKE BART F
IPC: C22B3/46
Filed: 2013-12-19
Abstract: A method of converting at least a portion of cesium sulfate to cesium hydroxide in solution is described. The method may include adding cesium sulfate to a mixed alkali metal formate blend solution and then adding potassium hydroxide to the mixed alkali metal formate blend in order to preferentially precipitate potassium sulfate from the mixed alkali metal formate blend solution, while converting the cesium sulfate to cesium hydroxide in the solution. The method further comprises separating at least a portion of the cesium sulfate from the solution to obtain a resulting solution of cesium hydroxide. In a further method, converting at least a portion of cesium sulfate or rubidium sulfate or both in solution to cesium hydroxide or rubidium hydroxide or both in solution with potassium hydroxide is described.
Patent CA-3060311-A1 (CA)
Inventor: HUNT NEIL
IPC: B60R21/235
Filed: 2018-04-26
Abstract: A method for producing a woven fabric comprises weaving fibers in a warp direction and a weft direction to form a fabric having a top surface and a bottom surface, wherein the warp fibers and weft fibers each comprises one or more filaments of a synthetic polymer having substantially uniform cross-sectional composition. At least a portion of the filaments in the fibers on the top and/or bottom surface of the fabric are then fused together in the presence of a heat transfer liquid or vapor added during the fusing step or added in a prior step of the fabric production process and retained by the filaments. The fusing step produces a treated fabric having a tensile strength in both the warp and weft directions of 1000 N or greater and having, in the absence of any coating, a static air permeability (SAP) of 3 l/dm2/min or lower.
Patent CA-3060706-A1 (CA)
Title: Combined administration of cysteine-aspartic protease inhibitors with p2y12 receptor antagonists protects the heart against myocardial infarction
Inventor: AUDIA JONATHON P
IPC: A61P9/10
Filed: 2018-04-27
Abstract: : The present disclosure generally pertains to methods of treating myocardial infarct involving administering a platelet anti-aggregate, a cysteine-aspartic protease inhibitor, and reperfusion therapy. In certain embodiments, the platelet anti-aggregate is at least one P2Y12 receptor antagonist or Glycoprotein Ilb/IIIa inhibitor, the cysteine-aspartic protease inhibitor is selected from the group consisting of Caspase-1, 4, 5, 11 and 12 inhibitors, and reperfusion therapy is percutaneous coronary intervention. In certain embodiments, the at least one P2Y12 receptor antagonist is selected from the group consisting of cangrelor, ticagrelor, clopidogrel and prasugrel. The disclosed methods provide an improved cardioprotective effect against infarction when compared with the current standard of care.
Patent CA-3061349-A1 (CA)
Inventor: OH DONG JIN
IPC: E04B1/88
Filed: 2019-08-12
Abstract: A sound insulation flooring material according to the present invention in which a heat resistance, sound insulation, and adhesion are improved is implemented by sequentially stacking a plurality of layers, a first balance layer, a second balance layer, a primer layer, a PE foam layer, and a PE  release paper layer. In this case, the primer layer includes a first composition, a second composition, and a curing agent, and the first composition includes a resin, propanol, 1-ethoxy-2-propanol, propyl acetate, isopropanol, butanone, and water.