baber/WOPTO huggingface dataset:
Patent NZ-595984-A (NZ)
Title: Production of encapsulated nanoparticles at commercial scale
Inventor: DODD AARON
IPC: A61K9/14
Filed: 2010-04-23
Abstract: 595984 The present disclosure relates to methods for producing particles of a biologically active material using dry milling processes as well as compositions comprising such materials, medicaments produced using said biologically active materials in particulate form and/or compositions, and to methods of treatment of an animal, including man, using a therapeutically effective amount of said biologically active materials administered by way of said medicaments. The method comprises the steps of: Dry milling a solid biologically active material, a facilitating agent and a millable grinding matrix selected from: lactose anhydrous, lactose monohydrate and mannitol, in a mill comprising a plurality of milling bodies, for a time period sufficient to produce particles of the biologically active material dispersed in an at least partially milled grinding material, Wherein the average particle size, determined on a particle number basis, is equal to or less than 2000 nm, or Wherein the particles have a median particle size, determined on a particle volume basis, equal or less than 2000 nm, and Wherein the total combined amount of biologically active material and grinding matrix in the mill at any given time is selected from the group consisting of: 1 kg, 2kg, 5 kg, 10 kg, 20 kg, 30 kg, 50 kg, 75 kg, 100 kg, 150 kg, 200 kg, 500 kg, 1000 kg, 1500kg and 2000 kg. Bioactive materials used in the method may include: cyclosporin A, progesterone, celecoxib, cilostazol, ciprofloxacin, 2,4-dichlorophenoxyacetic acid, anthraquinone, creatine monohydrate, glyphosate, halusulfuron, mancozeb, metsulfuron, salbutamol, sulphur, tribenuran and estradiol Facilitating agents used in the method may include surfactants such as: sodium lauryl sulfate, sodium docusate, sodium deoxycholate, Nlauroylsarcosine sodium salt, benzalkonium chloride, cetylpyridinium chloride, cetylpyridinium bromide, benzethonium chloride, PEG 40 stearate, PEG 100 stearate, poloxamer 188, Brji 72, Brji 700, Brji 78, Brji 76, Cremophor EL, Cremophor RH-40, Dehscofix920, Kollidon 25, Kraftsperse 1251, Lecithin, Poloxamer 407, polyethyleneglycol 3000, polyethyleneglycol, 8000, polyvinylpyrrolidone, sodium dodecylbenzenesulphonic acid, sodium octadecyl sulphate, sodium pentane sulphonate, soluplus HS15, Teric305, Tersperse 2700, Terwet 1221, Terwet 3785, Tween 80 and polysorbate 61.
Patent NZ-599032-A (NZ)
Title: Modulation of huntingtin expression
Inventor: HUNG GENE
IPC: C07H21/04
Filed: 2010-09-10
Abstract: Disclosed is a single-stranded modified oligonucleotide consisting of 12 to 30 linked nucleosides, targeted to a nucleic acid encoding huntingtin and capable of inhibiting huntingtin expression, wherein the linked nucleosides comprise at least 8 contiguous nucleobases of a sequence recited in SEQ ID NO: 22, 32, 6, 9, 10, 11, 12, 13, 14, 15, 18, 19, 20, 21, 23, 24, 25, 26, 27, 28, 29, 30, 33, 35, or 36, wherein the oligonucleotide comprises mixed phosphorothioate and phosphodiester internucleoside linkages, and wherein the sequences are as disclosed in the complete specification. Also disclosed is the use of said single-stranded modified oligonucleotide in the manufacture of a medicament for Huntington’s disease.
Patent NZ-604136-A (NZ)
Title: Methods for the manufacture of fuel pellets and other products from lignocellulosic biomass
Inventor: HARRIS KENNETH HILLEL PETER
IPC: A23K10/32
Filed: 2011-06-08
Abstract: Disclosed is a pellet used as a fuel source prepared by a process comprising the steps of: introducing a lignocellulosic biomass having a moisture content of less than about 30% by weight into a reactor; applying a vacuum to the reactor (which is preferably less than 500 torr and more preferably less than 200 torr); injecting steam having a temperature of between about 180°C and about 235°C into the reactor; maintaining the biomass in the reactor between about 1 and about 12 minutes; removing the treated biomass from the reactor; and forming the treated biomass into fuel pellets.
Patent NZ-616509-A (NZ)
Title: Preparation of maytansinoid antibody conjugates by a one-step process
Inventor: LI XINFANG
IPC: C07K16/00
Filed: 2012-03-29
Abstract: Disclosed is a process for preparing an antibody maytansinoid conjugate comprising the step of: (a) contacting an antibody with a maytansinoid to form a first mixture comprising the antibody and the maytansinoid, then contacting the first mixture with a bifunctional crosslinking reagent comprising a linker, in a solution having a pH of about 4 to about 9 to provide a second mixture comprising (i) the antibody maytansinoid conjugate, wherein the antibody is chemically coupled through the linker to the maytansinoid, (ii) free maytansinoid, and (iii) reaction by-products.
Patent NZ-619404-A (NZ)
Title: Compositions and methods for controlling a honey bee parasitic mite infestation
Inventor: PROBASCO GENE
IPC: A01P7/02
Filed: 2012-06-05
Abstract: Disclosed are methods and compositions for controlling a honey bee parasitic mite or for the treatment or prevention of a parasitic mite infestation in a honey bee hive. In particular embodiments, the invention provides a miticidal delivery device, wherein the device is a strip comprising about 30-35% potassium salts of hop beta acids, solvent and an emulsifier.
Patent NZ-620614-A (NZ)
Title: Can manufacture
Inventor: PRESSET ALAIN
IPC: B21D51/26
Filed: 2012-07-24
Abstract: A method for manufacture of a metal can body, comprises a first stretching stage, a second stretching stage and a drawing operation. The first stretching stage comprises positioning a sheet metal cup with a sidewall and an integral base, clamping an annular region on the base to define a first enclosed portion which includes a central part of the base, and deforming and stretching at least some of the first enclosed portion to thereby increase the surface area and reduce the thickness of the base. The second stretching stage comprises stretching a second enclosed portion of the base, the second portion including the same area or a second area than the first enclosed portion, the second area including the central part of the base, in which the step of clamping the annular region of the base is adapted to restrict or prevent metal flow from radially outside the annular region into the first enclosed portion during stretching. The drawing operation comprises drawing the cup into a can body by pulling and transferring material outwardly from the stretched and thinned base.
Patent NZ-625768-A (NZ)
Title: Fire actuated release mechanism to separate electronic door lock from fire door
Inventor: ELLIS DAVID D
IPC: E05B49/02
Filed: 2012-12-07
Abstract: Disclosed is an electronic door lock (12). The lock (12) includes a housing mechanically mountable to a first side of a fire door (10), wires (22) extending out of the housing and into the fire door (10) and a circuit board mounted within the housing. A fire actuated mechanical release mechanically releases the housing from a first side of the fire door (10) when a second side of the fire door (10) is exposed to a fire. A fire actuated electrical release electrically and mechanically disconnects the wires (22) from the circuit board when the second side of the fire door (10) is exposed to a fire. The mechanical release and electrical release cooperate to release the housing from connection to the first side of the fire door (10) and allow the housing to move sufficiently away from the fire door (10) to prevent ignition of any components of the electronic door lock (12) when the second side of the fire door (10) is exposed to a fire.
Patent NZ-627724-A (NZ)
Title: Ground anchor
Inventor: COLLINS BRIAN EDWARD
IPC: E02D5/80
Filed: 2013-08-09
Abstract: A ground anchor G includes an open ended hollow tubular body 1 adapted to accommodate a spigot 6 of a drive tool 8 such that the spigot 6 can be inserted through one end of the body 1. The body 1 is dimensioned and configured that once the spigot 6 is inserted an end of the spigot 6 is retained to sit flush with or slightly protrude through the open end of the body 1 so that the end of spigot 6 is in direct contact with the ground as the anchor G is being inserted in to the ground by the drive tool 8 so as to enable the end of the spigot to engage and subsequently break through hard ground and/or rocks that are in the path of the ground anchor being driven into the ground. An attachment means 3 is situated on the body 1 such that its longitudinal axis is offset to the central longitudinal axis of the body. An elongate means 4 is pivotally connected to a connecting means on the attachment means 3. Upon insertion of the ground anchor G into the ground by the drive tool a pulling force is applied to the elongate means 4 causing the hollow tubular body 1, due to the offset positioning of the attachments means 3 relative to the central longitudinal axis of the body 1, to pivot and transversely cross lock across the preformed hole in order to resist and prevent the body 1 and hence the ground anchor G from being removed from the ground.
Patent NZ-701408-A (NZ)
Title: Proteins that bind pi16 and uses thereof
Inventor: EASTAFF-LEUNG NICOLA GA-LING
IPC: C12N5/0783
Filed: 2011-04-18
Abstract: Discloses isolated populations of cells enriched for regulatory T (Treg) cells expressing PI16 and use of these populations in the manufacture of medicaments. Also discloses a method of diagnosis comprising detecting the ratio of PI16+ regulatory T cells to PI16- Treg cells from a site of inflammation.
Patent NZ-703458-A (NZ)
Title: Four-directional grating
Inventor: LIQI DU
IPC: E02D17/20
Filed: 2014-12-24
Abstract: The present invention relates to a reticular plastic tensile structure, and particularly, to a four directional grating. The grating may be used in civil engineering as a reinforcing and strengthening material, or protection and isolation material. Previous tensile reticular structure materials in the art at least have the following problem: the nodes of the grating are easy to be destroyed, and the grating is not resistant to the tangential force of the solum. It is an object of the present invention to overcome or ameliorate at least one of the disadvantages of the prior art, or to provide a useful alternative. The invention provides a four directional grating comprising: a plurality of nodes and a plurality of ribs, wherein the nodes and the ribs are connected to form a plurality of rectangular units, each of the rectangular units comprises four first nodes located at four vertexes of a rectangle, and a second node located at a diagonal intersection of the rectangle, wherein a line connecting two adjacent first nodes of the rectangle is a side of the rectangle, and each of the rectangular units further comprises a first rib located in the direction of a side of the rectangle to connect two adjacent first nodes, a third node located at a midpoint of each side of the rectangle, a second rib located at a diagonal of the rectangle, and a third rib passing through the second node and connecting the third nodes; the nodes comprise the first node, the second node and the third node; the ribs comprise the first rib, the second rib and the third rib; and the thickness of each of the nodes is larger than the thickness of each of the ribs, wherein the first node and the second node have the same size and thickness.
Patent NZ-706650-A (NZ)
Title: Method and apparatus for examining eggs
Inventor: DE KETELAERE BART
IPC: G01N33/08
Filed: 2013-09-04
Abstract: A non-destructive method for determining resistance to cracking of an intact egg, whereby said determining comprises at least one of the following steps a) and b): - a) determining a tensile stress developed in an eggshell of said intact egg, for example a tensile stress at a predetermined load; - b) determining an elasticity of said eggshell; wherein preferably the results of step a) and/or step b) are used in evaluating said resistance to cracking.
Patent NZ-711533-A (NZ)
Title: Method for manufacturing agricultural and horticultural granule formulation
Inventor: TANAKA NOBUYUKI
IPC: B01J2/20
Filed: 2014-03-24
Abstract: Provided is a method for manufacturing an agricultural and horticultural granule formulation, said method comprising molding a powdery pesticide composition into granules using a horizontal extrusion type granulator, characterized in that: the horizontal extrusion type granulator is equipped with a hopper for supplying a mixture of the powdery pesticide composition with water, a screw for kneading and extruding the mixture, a screw case for housing the screw, a screen for molding the kneaded mixture into strands, said screen being provided on a screw case wall on the side remote from the hopper that is in parallel to the screw axis, and a cooling means for cooling a screw case wall on the side of a screw bearing on the side remote from the hopper; and the powdery pesticide composition contains 20-80 wt% in total of component(s) having a solubility in water at a water temperature of 20oC at pH 3-9 of 4,000-500,000 ppm.
Patent NZ-713074-A (NZ)
Title: Bicyclic heterocycles as fgfr inhibitors
Inventor: WU LIANGXING
IPC: C07D471/04
Filed: 2014-04-18
Abstract: The present invention relates to bicyclic heterocycles of Formula IIIa, and pharmaceutical compositions of the same, that are inhibitors of one or more FGFR enzymes and are useful in the treatment of FGFR-associated diseases such as cancer.
Patent NZ-719549-A (NZ)
Title: Method, apparatus and compositions for the prophylaxis and treatment of colony collapse disorder
Inventor: DEL VECCHIO FRANCESCA
IPC: A61K36/886
Filed: 2012-03-14
Abstract: An automated apparatus for the prevention and treatment of the Colony Collapse Disease (CCD) through the administration of nutrients and therapeutic to bee colonies to be treated comprises a box-like container (10) of a material resistant to atmospheric agents which accommodates in its interior at least a first reservoir (9) being liquid-tight fitted with a stirrer (12) and accessible from the outside through a first nozzle (4), an atomizing device (15) of a liquid solution or suspension of nourishment contained in the tank, means for the delivery (2, 1) of the liquid solution or suspension atomized into micrometric drops outside the apparatus, and a control unit (7) programmed for timing the delivery of the solution or suspension to the outside, for the determination of the amount of solution or suspension delivered and for emitting alarm signals in case of malfunctions of the apparatus or reduction of the solution or suspension in a liquid contained in the reservoir (9) below a predetermined level. The apparatus is powered by direct current with the energy supplied by a solar panel (5) located outside of the container and electrically connected to the control unit (7). Further disclosed is a liquid solution or suspension of nutrients that can be delivered in a spray form through the above deceived automated apparatus for the prevention and treatment of the Colony Collapse Disease (CCD). The solution or suspension comprises in a single aqueous solution or suspension of a) tonics and nutritious ingredients, mainly consisting of: milk powder and/or yeasts, sugars and lower organic acids; b) natural antioxidants and antiseptics contained in the extracts of one or more aromatic or medicinal plants selected from: Crocus sativus, Pelargonium graveolens, Monarda citriodora, Myristica fragrans, Origanum vulgare and Origanum majorana; and c) substances medicinal to bees, selected from thymol, oxalic acid, extracts of Thymus vulgaris, extracts of Aloe arborescens, extracts of Beta vulgaris cv. altissima and mixtures of two or more of the same. Also disclosed is a method for the prevention and treatment of the Colony Collapse Disease (CCD) through the administration of nutrients and therapeutic to bee colonies to be treated, consisting in using the above described automated apparatus deliver in a spray form, the above described solution or suspension.
Patent NZ-720529-A (NZ)
Title: Methods for measuring enzyme activity useful in determining cell viability in non-purified samples
Inventor: ZWEITZIG DANIEL R
IPC: C12Q1/68
Filed: 2011-04-15
Abstract: Disclosed is a method of detecting an NAD-dependent ligase or phosphatase or a mixture thereof as an indicator of the presence of a microorganism in a sample, which method comprises: (a) contacting the sample with a nucleic acid molecule which acts as a substrate for enzyme activity of the NAD-dependent ligase in the sample, while not allowing interfering signals from DNA polymerase; (b) incubating the thus contacted sample under conditions suitable for NAD-dependent ligase activity; and (c) specifically determining the presence (and/or the amount) of an enzyme modified nucleic acid molecule resulting from the action of the NAD-dependent ligase on the substrate nucleic acid molecule, thereby to indicate the presence of the microorganism.
Patent NZ-732730-A (NZ)
Title: Game controller
Inventor: JOYNES MATTHEW
IPC: A63F13/92
Filed: 2015-07-29
Abstract: Disclosed herein is a system for controlling electronic games (e.g. video games). The system includes a computing device, a pair of confinement structures that provide a communication link with the computing device, a pair of control modules and a structural bridge that is a separate and distinct structure from the pair of confinement structures. The structural bridge include a conduit between the control modules and a fastening mechanism. The fastening mechanism facilitates placement of the computing device between the pair of confinement structures and the application of sufficient compressive load being placed on the computing device to securely hold the computing device between the pair of confinement structures, and an ability to remove the compressive load and allow removal of the computing device.
Patent NZ-742560-A (NZ)
Title: Device for sealing pipelines
Inventor: ODORI MAURO
IPC: F16L55/124
Filed: 2016-12-28
Abstract: A device for sealing a pipeline passageway, said device comprising: a rigid tube (2) having a longitudinal centerline oriented at an oblique angle relative to a vertical plane; a stationary disc (3) located toward a lower end of the rigid tube and having a truncated cone profile; a movable disc (4) located opposite the stationary disc and having a truncated cone profile facing that of the stationary disc (3), the moveable disc including a shank (40) passing through the stationary disc; an elastomeric sealing ring (50) located between the stationary and moveable discs and having a side profile complementary to the truncated cone profile, respectively, of the stationary and movable discs; at least one slider (70) projecting transversely from the rigid tube, the at least one slider including two faces (71, 72) parallel to each other but sloping relative to the longitudinal centerline of the rigid tube, the faces configured to engage a complementary portion of the shank; wherein a force applied to the at least one slider causes axial movement of the moveable disc relative to the stationary disc. The device provides a simple and easy to use configuration for a device for sealing pipeline passageways particularly beneficial for use in sealing smaller diameter pipeline passageways.
Patent NZ-744052-A (NZ)
Title: Attractants for rats
Inventor: GRIES GERHARD
IPC: A01N35/02
Filed: 2016-12-09
Abstract: Rat attractant compositions attractive to the rat species Rattus norvegicus are disclosed, which compositions are constituted of compounds found in the headspace volatiles of female urine odor. Said compositions are respectively termed female pheromone blend (FPB) and comprise 2-methyl-butyric acid, 3 -methyl-butyric acid, heptanal, hexanoic acid, 2-phenylacetaldehyde, nonanal, and decanal. Devices including the rat attractant compositions, and methods of using said rat attractant compositions are also disclosed.
Patent NZ-756855-A (NZ)
Title: Hexokinase 2-specific inhibitor for use in acute central nervous system injury
Inventor: YAN GUANGMEI
IPC: A61P25/28
Filed: 2018-02-06
Abstract: Provided are applications of a hexokinase 2-specific inhibitor in preparing medicament for preventing and treating an acute central nervous system injury disease that is mediated by microglial activation.
Patent NZ-768080-A (NZ)
Title: Variable guide bearing
Inventor: ELAHI SARMAD
IPC: G01B21/16
Filed: 2019-10-25
Abstract: A guide bearing system including a pad adjuster to traverse at least one bearing in a direction to adjust a radial clearance. The system can further include a sensor for measuring deviations in the radial clearance. In some embodiments, the guide bearing system includes a controller that receives a distance signal from the sensor measuring the radial clearance and signals the pad adjuster to traverse the at least one bearing to compensate for the deviations in the radial clearance.
Patent PT-101070-A (PT)
Inventor: KRISHNAN RAMASAMY
IPC: C09D11/02
Filed: 1992-11-18
Abstract: Printing inks comprising a pigment and an aqueous or non-aqueous solvent (or a mixture of such solvents) have reduced abrasiveness towards printing surfaces (e.g. gravure printing cylinders) by incorporation in the ink of an alkoxylated dibasic phosphate ester and at least one alkali metal salt of a dialkylsulfosuccinic ester.
Patent PT-103456-A (PT)
Title: Turnaround device for loaders and unloaders of bread baking ovens ensures that pieces of dough on introduction into oven remain in same position as that in which received by loader or are inverted when discharged inside oven
Inventor: EDUARDO YUS TOMAS
IPC: A21B3/07
Filed: 2006-04-04
Abstract: The turn-around device for loaders and unloaders of bread-baking ovens ensures that pieces of dough on introduction into an oven remain in the same position as that in which they are received by the loader or are inverted when discharged inside the oven. A frame is provided on which is fitted a mat bearing the dough pieces so that their sides terminate in expansions at the end for discharge from the mat, the inverter being housed between these expansions. The inverter is materialized as a type of rectangular column, in which are included two transversal bars spaced apart by an assembly of lateral pieces. The bars are adapted to the internal face of the expansions of the frame, in which the column is susceptible to swing via pivots. The turn-around device is for loaders and unloaders of bread-baking ovens.
Patent PT-107474-A (PT)
Title: Plataforma cónica flutuante em betão para a geração de energia eólica em mares profundos
Inventor: ABREU MIGUEL MARINHO MENDES
IPC: F03D3/00
Filed: 2014-02-21
Abstract: A INVENÇÃO É UM NOVO TIPO DE ESTRUTURA FLUTUANTE ADEQUADA AO SUPORTE DE APLICAÇÕES COM FORTES SOLICITAÇÕES HORIZONTAIS, COMO É O CASO DOS GERADORES DE ENERGIA EÓLICA. O PRINCIPAL MATERIAL ESTRUTURAL DA PLATAFORMA É O BETÃO ARMADO E ELA É PROJECTADA DE MODO A SE GARANTIR QUE ESTE BETÃO ESTARÁ SEMPRE SOB COMPRESSÃO E COMPLETAMENTE IMERSO. A PLATAFORMA É APTA A SER FUNDEADA EM MARES PROFUNDOS. ELA É COMPOSTA ESPECIALMENTE POR UM CONE ALONGADO INVERTIDO (1), DISPOSTO NA VERTICAL E COM OS CANTOS ARREDONDADOS. NO INTERIOR DESTE ENCONTRA-SE UM SISTEMA DE DISTRIBUIÇÃO DAS CARGAS (2) QUE GARANTE A COMPLETA COMPRESSÃO DAS PAREDES DE BETÃO. NO TOPO DA PLATAFORMA É COLOCADO O GERADOR EÓLICO (3). NA BASE DA PLATAFORMA EXISTE UMA TRELIÇA TRIDIMENSIONAL (4) EM AÇO QUE É USADA PARA LIGAR A PLATAFORMA AOS CABOS DE ANCORAGEM (5).
Patent RU-94005760-A (RU)
Inventor: SIROTA O A
IPC: G01S13/68
Filed: 1994-02-15
Abstract: FIELD: radiolocation equipment. SUBSTANCE: proposed system can be employed for operation as airborne radar in surveillance mode (tracking of target "in passing"). Channel of calculation of extrapolated coordinate using information on range and vertical speed of carrier of airborne radar is inserted into type 1 servo system. This channel compensates for error of system caused by maneuver of target height if mismatch signal exceeds threshold. EFFECT: enhanced operational reliability of proposed angle of elevation tracking system.