baber/WOPTO huggingface dataset:
Patent PT-1037687-E (PT)
Title: Device for enhancing transdermal agent flux
Inventor: WONG PATRICK S-L
IPC: A61K9/70
Filed: 1998-12-09
Abstract: A device ( 3 ) comprising a sheet member ( 6 ) having a plurality of microprotrusions ( 4 ) for penetrating the skin and a rigid support ( 15 ) contacting and extending across the sheet member ( 6 ) for transmitting an applied force evenly across the length and width of the sheet member ( 6 ) to reproducibly and reliably penetrate the skin with the microprotrusions ( 4 ).
Patent PT-962457-E (PT)
Inventor: FOX DAVID NATHAN ABRAHAM
IPC: A61K31/4427
Filed: 1999-06-01
Abstract: The present invention relates to a compound of the formula:- <CHEM> or a pharmaceutically acceptable acid addition salt or solvate thereof, wherein     R is C3-C7 cycloalkyl, (C3-C7 cycloalkyl)C1-C4 alkylene or benzyl; R<1> is phenyl optionally substituted by 1 or 2 substituents each independently selected from fluoro and chloro;   X is O or NSO2R<2>; and R<2> is C1-C4 alkyl or halo(C1-C4)alkyl, together with processes for the preparation of, intermediates used in the preparation of, compositions containing and uses of, such compounds having tachykinin antagonist activity.
Patent PT-1159747-E (PT)
Title: Cables with a recyclable coating
Inventor: ALBIZZATI ENRICO
IPC: C08L23/08
Filed: 1999-12-21
Abstract: Cable, in particular for medium-voltage or high-voltage electrical power transmission or distribution, for telecommunications or for data transmission, comprising a conductor and at least one coating layer based on a non-crosslinked polymer material comprising a thermoplastic reactor elastomer with an ethylene-based elastomeric phase co-polymerized with an alpha-olefin and a propylene-based thermoplastic phase, in which the said elastomeric phase in the said thermoplastic reactor elastomer is at least 45% by weight relative to the total weight of the thermoplastic reactor elastomer, and the said thermoplastic reactor elastomer has value of enthalpy of fusion of peaks present below 130° C. and attributable to polyethylene sequences, such as HIFAX(R) KS080.
Patent PT-1112194-E (PT)
Inventor: FLIEGE DIETER
IPC: B60J7/10
Filed: 1999-09-01
Abstract: The invention relates to a side-rail coupling for tarpaulin covers of vehicle superstructures, notably a coupling for the upper side-rails of cover frames which can be assembled and comprise separable longitudinal sections of running or guide rails for a telescopic tarpaulin cover. The side-rails (3) have at least one hollow profile chamber and running or guide rails connected to same and serve to support and guide rollers or roller bogies (4) on which hoops (5) carrying the tarpaulin are supported laterally against the cover frame. Adjacent longitudinal sections of the side rails (3) can be removably coupled using coupling elements which engage the hollow profile chamber in a positive fit. To improve handling, reduce weight and increase operating safety the invention provides for the coupling elements to be embodied by profiled material sections whose cross-sectional shape is substantially congruent with the inside cross section of the hollow profile chamber and are fitted with at least one bolt element for each of the longitudinal side rail (3) sections to be coupled together. The bolt elements can be moved against a spring force into a position perpendicular to the longitudinal axis of the longitudinal sections and cooperate with a complementary recess configured in the walls of the hollow profile chambers of the longitudinal side rail (3) sections to be coupled.
Patent SG-72785-G (SG)
Title: 2-(1-piperazinyl)-2,4,6-cycloheptatrien-1-one derivatives, processes for their preparation, intermediates used in the processes and the preparation thereof and pharmaceutical compositions containing the derivatives
IPC: C07D233/76
Filed: 1985-10-05
Abstract: 2-(1-Piperazinyl)-2,4,6-cycloheptatrien-1-one derivatives of formula   <CHEM> and therapeutically acceptable acid addition salts thereof exhibit dopamine-receptor stimulating activity in a mammal and are useful for treating hyperprolactinemia, galactorrhea, amenorrhea, impotence, Parkinsonism, diabetes, acromegaly, hypertension and other central nervous system disorders. In the formula R<1> is hydrogen or a specified substituent, R<2> is hydrogen or lower alkyl and R<3> is hydrogen or a specified radical. Processes for preparing the derivatives and pharmaceutical compositions containing them are also disclosed.
Patent IE-820463-L (IE)
Title: Cephalosporins
IPC: C07D501/34
Filed: 1982-03-02
Abstract: The present invention relates to derivatives of the family of cephalosporins, of formula:    <IMAGE>  (I)  in which   <IMAGE>  is an acid, a salt or an ester of this acid, R1 is a group of form <IMAGE>  in which RA and RB are H or alkyl or form a saturated cyclobutyl or cyclopentyl ring and RC is H or COOH, R2 is a thiazolium salt or a OCOCH2RD group in which RD is a 1,3-thiazol-4-yl group. The invention also relates to a process for preparing the products of formula (I) and to drugs containing said products.
Patent IE-890546-L (IE)
Title: Bone cement
IPC: A61L27/00
Filed: 1989-02-21
Abstract: There is disclosed a bone cement composition comprising (a) a liquid component comprising a monomer of an acrylic ester and (b) a powdered component comprising, based on the weight of the powdered component,   (i) from 0 to about 20 percent of a methyl methacrylate homopolymer,   (ii) from about 30 to about 60 percent of a methyl methacrylate-styrene copolymer, and (iii) from about 30 to about 60 percent of a methyl methacrylate-butyl methacrylate copolymer. i
Patent IE-33791-L (IE)
Title: Moulding concrete pipes.
IPC: B28B21/24
Filed: 1969-06-10
Abstract: Pipes having dense, watertight concrete walls are produced by vibrating a rotating mould suspended on a roller shaft as the mold is being filled, and continuing its rotation without vibration for a short time after the mold is filled. Vibration is attained by ridges or fingers which can be made effective, or not, to vibrate the mold as it is rotating. In one form, fingers on a roller shaft are slidable between ineffective positions and positions where they serially engage a smooth running surface on the mold. In other forms, a mold is movable from a position where it is supported by engagement of a ridged running surface on either the roller shaft or the mold with a cylindrical surface on the other to a position where the cylindrical surface on the mold runs on the roller shaft or on an auxiliary sleeve without vibration.
[US3642413A]
Patent IE-780914-L (IE)
Title: Fibre reinforced building product.
IPC: B28B1/52
Filed: 1978-05-05
Abstract: A fibrous reinforcing element made from oriented polyolefin material for reinforcing a matrix material such as cement has longitudinally varying cross-sections and frayed surface portions from which fibrils extend. The element has cross-sections which vary along its length, a characteristic which combines with the fibrils of the frayed surface portions to facilitate anchoring of the element in the matrix. The anchoring and strength characteristics make the element particularly useful for constructing cement building products or any product produced from a matrix binding agent. The element is in the form of a fiber made from a polyolefin film which is stretched at least fifteen times and then cut by cutting means along lines at least partially transverse to the direction of orientation. In the preferred embodiment a building product formed from a matrix of Portland cement has dispersed therein, a plurality of fibrous reinforcing elements at least a portion of which are the individual polyolefin fibers described in accordance with the invention. By uniquely providing a combination of the inventive fibers with fibers of other types within the cement matrix, improved anchoring and dispersion of the fibers is achieved, while the improved strength characteristics of the elements contributes to a building product of unusually improved strength.
Patent FI-803969-L (FI)
Inventor: STAEHLE HELMUT
IPC: A61K31/415
Filed: 1980-12-19
Abstract: Compounds of the formula   <IMAGE>   wherein R is bromine or trifluoromethyl, and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as bradycardiacs, analgesics and locomotion inhibitors.
Patent FI-810255-L (FI)
Inventor: SLEIGH THOMAS
IPC: C07J41/00
Filed: 1981-01-29
Abstract: New and pharmacologically useful 17-amino-16-hydroxy-steroids of the androstane and oestrane series are disclosed having the formula I: <CHEM> and pharmaceutically acceptable non-toxic acid addition salts thereof, wherein: R1 = H or hydrocarbyl of one to six carbon atoms (preferably lower alkyl, such as methyl); R2 = H or hydrocarbyl of one to six carbon atoms (preferably lower alkyl, such as methyl);  R3 = a free, esterified or etherified hydroxyl group; ring A inclusive carbon atoms 6 and 9 has one of the following configurations: <CHEM>  in which  R4 = a free, esterified or etherified hydroxyl group; R5 = O or H(R7), wherein R7 is a free, esterified or etherified hydroxyl group;  R6 = H or methyl; and the dotted lines represent an optional double bond in 4,5- or 5,6-position;  as well as the enantiomers and racemates of these steroids. The novel compounds have antiarrhythmic properties.
Patent FI-831167-L (FI)
Inventor: FANCHER PHILIP DANIEL
IPC: G08B13/24
Filed: 1983-04-06
Abstract: An article surveillance system employs a label or tag containing a non-linear impedance element, such as a semi-conductor diode, connected to a metal antenna loop configured to pick up two distinct radio frequency transmissions displaced on either side of a selected center frequency. The non-linear impedance element connects opposing sides of a closed loop section at one end of the antenna to form a tuned tank circuit having a resonant frequency twice that of the selected center frequency. A first transmitter generates a tone modulated radio frequency displaced on one side of the center frequency, and a second transmitter generates a continuous wave radio frequency displaced from the center frequency on the other side. Both transmitter signals are fed separately to respective radiating antennae located adjacent to a surveillance area. The antennae are chosen to produce circularly polarized transmission of both frequencies within the surveillance area. The two different frequencies picked up by the transponder antenna are mixed by the non-linear impedance causing the tank circuit to resonate at a single higher frequency equal to their sum, which is double the center frequency; that resonant frequency is reradiated to be picked up by a receiver antenna or antennae suitably placed with respect to the surveillance zone to be detected by a very narrow band receiver responsive to the sum frequency. The modulating tone signal is derived from the received signal to produce a gradually increasing charge that is compared against a preselected threshold level to trigger an alarm for a fixed interval only when the detected signal is of a sufficient strength and duration.
Patent FI-831401-L (FI)
Inventor: RUDOLF HANS-WERNER
IPC: H02H9/04
Filed: 1983-04-25
Abstract: 1. A circuit arrangement for surge voltage protection of interface circuits (SLIC 1 to SLIC 3) constructed of semiconductor components and connected in groups to a supply voltage source to connect two-wire, analogue subscriber connection lines (TL) to telephone exchanges, where the circuit arrangement contains, in respect of each interface circuit, a diode bridge whose diodes (D1 to D4) are normally biased in the blocking direction by the supply voltage and which has one diagonal connected to the two wires of the subscriber connection line (TL) in question and its other diagonal connected to the supply voltage via at least one blocking element (Da, L) which assumes the blocked state when a surge voltage occurs and is common to a plurality of interface circuits, and where the circuit arrangement likewise contains by-pass circuit elements (C, V) common to a group of interface circuits via which leakage currents are diverted from the last-mentioned bridge diagonal to a circuit point which carries reference potential on the occurrence of a surge voltage, characterised in that by-pass circuit elements (C, V) are used which flatten and/or limit voltage swings occurring on the occurrence of surge voltages across the bridge diagonal to which they are connected.
Patent IE-39293-L (IE)
Title: Detecting antibiotics
IPC: G01N33/12
Filed: 1974-05-29
Abstract: A method for the rapid determination of the presence or absence of residues of antibiotic such as penicillin, in liquids, for example milk, and meat comprising introducing spores of a microorganism which possesses a high sensitivity for the antibiotic to be determined into an agar medium so that the spores are prevented from starting to germ due to lack of nutrients, but stay alive, and being sufficiently heavily inoculated that after addition of nutrients and incubation at or near optimal temperature in a short time sufficient growth has proceeded so that growth is either observable visually or its indicated by an indicator added to the agar medium, the said spore culture being allowed to solidify in upright test vessels having a cross-sectional dimension sufficiently small to require as little of the agar medium as possible but sufficiently large to enable a correct determination of inhibition of growth of the microorganism to be made, and having a height so that the vessel can contain a sufficient amount of medium and a sufficient amount of sample of liquid to be tested, placing on the agar surface nutrients required for growth, followed, if desired, after a pre-incubation period, by addition of a predetermined amount of sample liquid to be tested to the test vessel, and incubating the contents of the test vessel at or near optimal temperature for a predetermined time so that the extent of growth or inhibition of growth of the microorganism read in a vertical sense, indicates absence or presence of the antibiotic.
[US3941658A]
Patent IE-861336-L (IE)
Title: Thiazolidinedione derivatives
IPC: A61K31/47
Filed: 1986-05-20
Abstract: Hypoglycemic 2,3-dihydro-5-benzo[b]furanyl-2,3-dihydro5-benzo[b]thienyl-, 3,4-dihydro (2H)-6-benzo-pyranyl- and 6-thiochromanyl-thiazolidine-2,4-diones of the formula 
<CHEM>
 and pharmaceutically acceptable salts thereof, method for their use in treatment of hyperglycemic animals and pharmaceutical compositions containing them.
Patent IE-801529-L (IE)
Title: Ketimine magnesium halides
IPC: C07F3/02
Filed: 1980-07-23
Abstract: Fluorinated alkenylamines of the Formula V <IMAGE> Formula V wherein n represents 0, 1, 2 or 3; R1 represents hydrogen or C1-C10 alkyl and Y represents (a), when n represents O, CH2F, (b), when n represents 1, CH2F or CHF2, or (c) when n represents 2 or 3, CH2F, CHF2 or CF3 are novel process intermediates. They are obtained by hydrolysis and subsequent reduction of the corresponding alkenyl fluorinated methyl ketimine magnesium halides, which are novel compounds resulting from reaction of the corresponding alkenyl magnesium halides with the corresponding fluorinated acetonitriles. The fluorinated alkenylamines of Formula V are oxidized while the amino group is protected to provide, after removal of the amine protecting group, the corresponding fluorinated methyl aminoalkanoic acids which are useful pharmacological or anti-bacterial agents.
[US4353828A]
Patent IE-41785-L (IE)
Title: Nickel alloy
IPC: C22C19/03
Filed: 1975-07-22
Abstract: 1449788 Nickel-base alloys HOWMEDICA Inc 20 Aug 1975 [26 Sept 1974] 34684/75 Heading C7A Corrosion-resistant, hot workable, dental alloys have a composition in the following range, in per cent by weight:- Ni 60 - Cr 10 - 25 Mn 0À5 - 1À5 Ga 1 - 7À5 Sn 0 - 9 Mo 0 - 10 Cu 0 - 5 Si 0 - 4 Al 0 - 2 Co 0 - 5 C 0 - 0À2 the total of Ga and Sn not exceeding 10.
[GB1449788A]
Patent IE-781681-L (IE)
Title: Phosphonic acid derivatives
IPC: C11D3/36
Filed: 1978-08-18
Abstract: 1. Process for the production of N-carboxyalkane-aminoalkane diphosphonic acids, N-carboxy-alkane-azacycloalkane-diphosphonic acids and N-carboxyalkane-aminoaryl-diphosphonic acids of the general Formula I see diagramm : EP0000930,P8,F1 wherein R**1 is a hydrogen atom, or an alkyl radical of formula -(CH2 )xCH3 with x = 0 to 10, or a hydroxy ethyl radical, or a carboxy methyl radical, or a phenyl radical, or an N,N-bis-(carboxyalkyl)-aminoalkyl radical, or a methyl- or ethyl-phosphonic acid radical, or R**1 together with R**2 is an alkylene group with 3 to 5 C-atoms and forms an azacycloalkane ring with the grouping see diagramm : EP0000930,P8,F2 R**2 is a hydrogen atom, or a methyl radical, or the same radical as R**3 , or R**2 together with R**1 is an alkylene group with 3 to 5 C-atoms and forms an azacycloalkane ring with the grouping see diagramm : EP0000930,P8,F3 R**3 is a carboxy-substituted unbranched alkyl radical with the formula (CH2 )m COOH in which m = 1 to 12, or a 2-carboxy-2,2-dimethyl ethyl radical, or a 1,2-dicarboxy-ethyl radical, characterised in that an amino alkane, azacyclo alkane or aminoaryl alkane diphosphonic acid of the general Formula II see diagramm : EP0000930,P8,F4 wherein R**1 is defined as stated in Formula I and R**4 is a hydrogen atom, or a methyl radical, or R**4 together with R**1 is an alkylene group with 3 to 5 C-atoms and forms an azacyclo alkane ring with the grouping see diagramm : EP0000930,P8,F5 is heated with a corresponding unbranched or branched halogen alkane carboxylic acid or halogen succinic acid, its alkali salts, earth alkali salts or alkali-heavy metal salts or its esters in a molar ratio of 1:1 to 1:3 in aqueous medium at a temperature between 50 and 160 degrees C and at a pH value between 4.0 and 12.0 until the reaction is concluded.
[EP0000930A1]
Patent IE-801701-L (IE)
Title: Piping leakage detection
IPC: E21B47/10
Filed: 1980-08-12
Abstract: A method of testing for leaks in tubing and tube joints comprises placing within the tube to be tested a tool having spaced seals so that the seals are arranged on opposite sides of the joint to be tested in engagement at a constant pressure against the internal surface of the tubing. A search fluid such as 1 to 2% helium in air is passed through the tool under pressure and then out from the tool into the annular space between the outside surface of the tool and the inside surface of the tubing between the two seals. The presence of any helium is detected by means of a helium detector for example a mass spectrometer which has a probe extending to a gas trap surrounding the joint to be tested.
[US4429566A]
Patent IE-821857-L (IE)
Title: Amidines
IPC: C07D487/04
Filed: 1982-07-30
Abstract: Novel amidines, especially N,N'- bridged carboxylic acid amidines of the general formula   <IMAGE> in which R1 represents phenyl optionally substituted in the p-position by lower alkylthio having up to and including 4 carbon atoms, by lower alkanesulphinyl having up to and including 4 carbon atoms, by lower alkoxy having up to and including 4 carbon atoms or by halogen having an atomic number of up to and including 35, thienyl or pyridyl optionally substituted by lower alkyl having up to and including 4 carbon atoms, R2 represents carboxymethyl or, secondly, lower alkoxycarbonylmethyl having up to and including, 5 carbon atoms Ph represents 1,2-phenylene optionally substituted in the p-position to the nitrogen atom by lower alkoxy having up to and including 4 carbon atoms or by halogen having an atomic number of up to and including 35 and alk represents vinylene, and salts thereof, have, inter alia, anti-inflammatory activity and can be used in pharmaceutical preparations as an active ingredient in medicaments. They are manufactured according to methods known per se.
Patent IE-891879-L (IE)
Title: Amino Acid Derivatives
IPC: C07D471/04
Filed: 1989-06-12
Abstract: Compounds of the formula <CHEM> wherein R<1> represents alkoxycarbonyl, aralkoxycarbonyl, alkanoyl, cycloalkylcarbonyl, aralkanoyl, aroyl, heterocyclylcarbonyl, alkylsulphonyl, arylsulphonyl, monoaralkylcarbamoyl, cinnamoyl or alpha -aralkoxycarbonylaminoalkanoyl and R<2> represents hydrogen or R<1> and R<2> together with the nitrogen atom to which they are attached represent a cyclic imide group of the formula <CHEM> in which P and Q together represent an aromatic system; R<3> represents alkyl, cycloalkyl, aryl, aralkyl, heterocyclylalkyl, cyanoalkyl, alkylsulphinylalkyl, carbamoylalkyl or alkoxycarbonylalkyl or, when n stands for zero, R<3> can also represent alkylthioalkyl or, when n stands for 1, R<3> can also represent alkylsulphonylalkyl; R<4> represents alkyl, cycloalkyl, cycloalkylalkyl, aryl or aralkyl; R<5> represents hydrogen and R<6> represents hydroxy or R<5> and R<6> together represent oxo; R<7> and R<8> together represent a trimethylene or tetramethylene group which is optionally substituted by hydroxy, alkoxycarbonylamino or acylamino or in which one -CH2- group is replaced by -NH-, -N(alkoxycarbonyl)-, -N(acyl)- or -S- or which carries a fused cycloalkane, aromatic or heteroaromatic ring; and R<9> represents alkoxycarbonyl, monoalkylcarbamoyl, monoaralkylcarbamoyl, monoarylcarbamoyl or a group of the formula <CHEM> in which R<1><0> and R<1><1> each represent alkyl; and their pharmaceutically acceptable acid addition salts inhibit proteases of viral origin and can be used as medicaments for the treatment or prophylaxis of viral infections. They can be manufactured according to generally known procedures.
[EP0346847A2]
Patent IE-782103-L (IE)
Title: Magnetic disk assembly
IPC: G11B17/03
Filed: 1978-10-24
Abstract: A thin flexible magnetic disk rotatably disposed in a cartridge of rigid material and protected thereby. The disk is loosely mounted on a driving hub assembly and has an arrow shaped center hole surrounding a central round hub portion of the hub assembly. A drive pin is carried by the hub assembly and extends loosely through a corresponding hole located in the disk and spaced from the center of the hub assembly and located on a radial line preferably of about 90 degrees with respect to a radial line passing through the apex of the straight hole edges forming the arrow so that the disk is automatically centered on the hub assembly due to any restraint on the disk during its rotation.
[US4149207A]
Patent IE-812166-L (IE)
Title: Aerator for purification of waste water
IPC: B01F3/04
Filed: 1981-09-17
Abstract: A horizontal-axis aerator for use in a waste water purification system includes a cylinder having a horizontal axis, a first series of parallel blades on the surface of the cylinder and extending in directions nonparallel to the axis, and a second series of parallel blades on the surface of the cylinder and extending in directions nonparallel to the axis. The directions of the first series of blades are opposite to the directions of the second series of blades, with respect to the axis. The first and second series of blades intersect each other, such that upon the aerator being partially immersed in a body of waste water to be treated and being rotated therein, at any rotational position of the aerator about the axis, a constant portion of the total blade length of all of the blades of the aerator will be immersed in the waste water.
[US4539112A]
Patent IE-882692-L (IE)
Title: New cephem compound and a process for preparation thereof
IPC: C07D501/04
Filed: 1988-09-06
Abstract: A cephem compound of the formula : <CHEM> wherein R<1> is amino or a protected amino, R<2> is lower alkyl which may have one or more suitable substituent(s), R<3> is COO<(-)>, carboxy or a protected carboxy, R<4> is hydroxy(lower)alkyl or protected hydroxy(lower)alkyl, R<5> is amino or a protected amino, R<6> is hydrogen or lower alkyl, X<(-)> is an anion, and n is O or 1, with proviso that (i) when R<3> is COO<(-)>, then n is 0, and (ii) when R<3> is carboxy or a protected carboxy, then n is 1, and pharmaceutically acceptable salt thereof, processes for their preparation and pharmaceutical compositions comprising them as active ingredient in admixture with pharmaceutically acceptable carriers.
[EP0307804A2]