baber/WOPTO huggingface dataset:
Patent FR-2751650-B1 (FR)
Inventor: DODEY PIERRE
IPC: C07D401/12
Filed: 1996-07-24
Granted: 1998-10-09
Abstract: PCT No. PCT/FR97/01377 Sec. 371 Date Jan. 25, 1999 Sec. 102(e) Date Jan. 25, 1999 PCT Filed Jul. 23, 1997 PCT Pub. No. WO98/03503 PCT Pub. Date Jan. 29, 1998Compounds selected from the group which consists of the compounds of formula (I), wherein each of X1 and X2 which are the same or different, is halogen or a C1-3 alkoxy group, R1 is H, CF3 or a C1-3 alkyl group, R2 is a hydrogen atom or an OH group, A is group (a), (b) or (c), B is a single bond, -CO-, -CO-CH2-, -CO-CH2-O-, -CO-CH=CH or -SO2-, m is 2 or 3, N is 0, 1, 2 or 3, R3 is a hydrogen atom or a methyl group and W is CH or N, the amidine group C(=NR2)NH2 being in the 2, 3 or 4 position on the aromatic ring, and addition salts thereof, are disclosed. A method for preparing said compounds, and the therapeutical use thereof, particularly for treating diseases in which bradykinin is involved, are also disclosed.
Patent FR-2753706-B1 (FR)
IPC: A61K31/4427
Filed: 1996-09-20
Granted: 1998-10-30
Abstract: N-Substituted cyclic amines of formula (I), their optical and geometric isomers, and their salts are new. X = -CH=, -CH2-, or -O-; R1 = 1-6C alkyl, optionally substituted by one or more halo; R2 = saturated or unsaturated 3 - 6C monocyclic hydrocarbon, optionally substituted by one or more halo or OH, saturated or unsaturated 7 - 10C polycyclic hydrocarbon optionally substituted by one or more halo or OH, 1-13C saturated or unsaturated hydrocarbon optionally substituted by one or more halogens or OH, and additionally may be substituted by phenyl, 3-6C monocyclic, or 7-10C polycyclic hydrocarbons that may themselves be substituted by halo or OH; R = phenyl, biphenylyl, or naphthyl, 5-membered aromatic heterocycle with 1-4 hetero atoms, 6 membered aromatic heterocycle with 1-3 N atoms, saturated or unsaturated aromatic (sic) bicyclic groups of 9 or 10 C atoms with 1-4 heterocyclic atoms, or partially saturated aromatic bicyclic having one or more carbonyl functions; R is optionally substituted by 1-3 groups selected from halo, R1, -O-CO-R1, CN, NO2, R3, SR3, COR3, COOR3, NR3R4, NCOR3, CONR3R4, and SO2NR3R4; R3, R4 = H or R1.
Patent FR-2779345-B1 (FR)
Inventor: LAGARDE ISABELLE
IPC: A61K35/74
Filed: 1998-06-03
Granted: 2003-02-14
Abstract: The invention concerns the use of micro-organism extracts in cosmetic or pharmaceutical compositions for inhibiting body odours.
Patent FR-2781868-B1 (FR)
Inventor: CASTELLANET FREDERIC
IPC: F17C5/06
Filed: 1998-07-29
Granted: 2000-09-15
Abstract: The installation comprises a helium source (2) with an internal volume of at least 7000 liters; a network (4) of secondary pipes (4a, 4b, 4c) each feeding at least one production line (5a, 5b, 5c) using gaseous helium; a main pipe (3, 3a, 3b) connected upstream to the helium source and downstream to the network. Each production line is fed with helium from the helium source The installation comprises a helium source (2) with an internal volume of at least 7000 liters; a network (4) of secondary pipes (4a, 4b, 4c) each feeding at least one production line (5a, 5b, 5c) using gaseous helium; a main pipe (3, 3a, 3b) connected upstream to the helium source and downstream to the network. Each production line is fed with helium from the helium source. Preferred Features: The helium source has an internal volume of at least 8000 liters, and preferably more than 20000 liters or, especially, more than 40000 liters. The source is movable or fixed. The main pipe is also connected to at least one of the following: A heat exchanger (7), a balance capacity (8), means of purifying the helium (9) and a compressor (10). The installation also includes means of controlling the flow and/or the pressure in the main pipe and/or each secondary pipe in the network. The production lines are: Bottle filling lines; balloon envelopes; airbag fillers; helium dosing lines for metalwork; electronic production lines making wafers or printed circuits, or optic fiber production lines. The production lines are independently connected to the main line via the network. The helium extracted from the source is liquid or supercritical. An Independent claim is included for a process for supplying helium using the above device by feeding a main pipe with helium from a source, and channeling the helium to a network of secondary pipes each feeding at least one production line using helium gas. The helium is extracted from the source in liquid or supercritical form and is vaporized to obtain helium gas. The pressure and/or flow of helium in the main pipe is adjusted as a function of the sum of the pressures and/or flows in the secondary pipes.
Patent FR-2782782-B1 (FR)
Inventor: LAMBERTI DOMINIQUE
IPC: F23N5/26
Filed: 1998-09-02
Granted: 2001-01-12
Abstract: The burner (1) carries a combustion head (2) mounted on the cover (3) of a turbine for providing air ventilation, together with an electronic command and security box (4). The protective cover (5) carries on its front side a display (6) comprising a module (7) receiving infra-red signals from a transmitter (8) on the command box (4).
Patent FR-2795522-B1 (FR)
Inventor: LEMANCZYK JERZY MICHAL
IPC: G01R29/10
Filed: 1999-06-23
Granted: 2001-08-10
Abstract: Electromagnetic radiation is emitted from an antenna (2) and detected by a measuring probe (4). The probe (4) has a receiving element (8) mounted on a wave guide support (6) which transmits radiation to real time measuring equipment (50). A screen (7) in the form of a metallic conical skirt is attached to the wave guide support (6) and the probe is mounted on a rear plate (5)
Patent HR-P990416-B1 (HR)
Title: Pharmaceutical compositions containing eletriptan hemisulphate and caffeine
Inventor: HARDING VALERIE DENISE
IPC: A61P3/04
Filed: 1999-12-30
Abstract: PCT No. PCT/EP98/04176 Sec. 371 Date Jan. 27, 2000 Sec. 102(e) Date Jan. 27, 2000 PCT Filed Jul. 1, 1998 PCT Pub. No. WO99/01135 PCT Pub. Date Jan. 14, 1999The present invention provides an aqueous pharmaceutical composition comprising 5 to 200 mg/ml of eletriptan hemisulfate and from 0.5 to 2.0% weight/volume of caffeine.
Patent HU-224397-B1 (HU)
Title: Magnetic system
Inventor: GENSCH OLAF
IPC: H01H71/24
Filed: 1999-08-11
Abstract: The invention relates to a magnetic system for circuit breakers and a method of producing the same. The magnetic system has a sleeve (2) which is housed in a support (1). Said sleeve is enclosed by a coil (3) and has an armature (7) which is slideable in the sleeve. Said armature, in its inoperative position, rests against a dead stop (23) which is formed in the interior of said sleeve and is held therein by a spring-biased plunger (4) which is supported by the armature. Said plunger is impinged by a spring (5) which rests partially on the plunger and partially on an insert (6) in the sleeve. During assembly, the parts are simply inserted into the sleeve in the predetermined order and are fixed in an operative position by inserting the insert or inserting the sleeve into the support, thereby allowing the use of more inexpensive parts and simplifying assembly.
Patent HU-221852-B1 (HU)
Title: Hexahydronaphthalene ester derivatives, their preparation and pharmaceutical compositions containing them
Inventor: ISHIHARA SADAO
IPC: C07C69/712
Filed: 1994-01-28
Abstract: Compounds of formula (I): <CHEM>  [wherein R<1> represents a group of formula (II) or (III): <CHEM> R<2> is hydrogen or a group of formula -OR<3>; R<3>, R<3a> and R<3b> are each hydrogen, a hydroxy-protecting group, alkyl, alkanesulphonyl, halogenated alkanesulphonyl or arylsulphonyl; R<4> is hydrogen or a carboxy-protecting group; R<5> is alkyl, alkenyl, alkynyl, aryl, aralkyl or a fused polycycle; and W is alkylene] and their salts and esters have the ability to inhibit the synthesis of cholesterol, and can thus be used for the treatment and prophylaxis of hypercholesterolemia and of various cardiac disorders.
Patent JP-2988932-B1 (JP)
Title: テンション制御した巻取機
IPC: B65H23/182
Filed: 1999-01-20
Granted: 1999-12-13
Abstract: 【要約】
【解決手段】  巻取機において、アンリールスタンドの 原反ロールとフィードロールとの間におけるシートのテ ンションは、原反ロールに回転トルクを与える第１のＡ Ｃサーボモータの電流値のみを制御することによって行 われ、フィードロールと巻取ロールとの間におけるシー トのテンションは、フィードロールのための第２のＡＣ サーボモータとサーフェイスロールのための第３のＡＣ サーボモータとの間の速度制御をすることによって、ま たは、巻取ロールに回転トルクを与える第３のＡＣサー ボモータの電流値が所望値となるよう回転数を制御する ことによって行われる。この場合において、シートのテ ンションは、加減速時の慣性（ＧＤ 2  ）を補償した原反 ロール軸または巻取ロール軸にかかるトルクを演算する ことにより求める。
【効果】  巻取機のシステム全体の構成を簡単化でき、 安価なものとすることができ、しかも、タイムラグの少 ない精度の高いテンション制御を行える。
Patent JP-3001057-B1 (JP)
Title: スイッチング電源装置及びその制御方法
IPC: H02M3/28
Filed: 1999-03-02
Granted: 2000-01-17
Abstract: 【要約】
【課題】  入力回路に大容量の電解コンデンサを接続す ること無しに、異常発振の発生を無くし小形で安定で安 全なスイッチング電源装置を提供する。
【解決手段】  スイッチング電源装置において、スイッ チング手段に流れる電流を検出した検出電圧Ｖｐに、一 定の傾きののこぎり波電圧Ｖｎを加えて和電圧Ｖｗを得 る。和電圧のピーク値を一定に保つように、前記スイッ チング手段のオフタイミングを決定することにより、異 常発振に関与するオープンループゲインが小さくなるの で異常発振の発生を防止できる。
Patent JP-3034518-B1 (JP)
Title: ガスガン用レ―ザ―光線照射装置
IPC: F41B11/00
Filed: 1999-03-15
Granted: 2000-04-17
Abstract: 【要約】
【目的】  ガスガンとともに使用して射撃の感触を得る ことができる長射程のレーザー光線照射装置の提供。
【構成】  ガスガン４０の発射操作により噴射したガス の圧力によりスイッチ部２０の接点を閉じてレーザーモ ジュール２８に通電し、誤差なく直進した弾丸の軌道に 相当するレーザー光線５４を目標に照射可能とする。
Patent JP-2872997-B1 (JP)
Title: 施肥機または施肥播種機の施肥部における肥料混和装置
IPC: A01C21/00
Filed: 1998-03-24
Granted: 1999-03-24
Abstract: 【要約】
【課題】簡単に構成して施肥機または施肥播種機の肥料 落下樋の下端から流落する肥料を飛散させると共に土と 混和して肥料濃度を分散し、肥料の濃度障害による作物 の発芽不良を無くして作物の初期生育を向上する上に、 無駄な施肥量を防いで経済的になるようにする。
【解決手段】肥料箱の下方に施肥溝切りコルタを設け、 上記肥料箱の肥料送出し口に上口を臨ませて縦に配置し た肥料落下樋の下端を上記施肥溝切りコルタの後方上部 内に臨ませ、上記施肥溝切りコルタの後方下部内で上記 肥料落下樋の下端の下方には、多数の横方向の羽根を設 けて接地回転する羽根車を回転自在に軸支した羽根車体 を配設して施肥機または施肥播種機の施肥部における肥 料混和装置を構成する。
Patent NL-1041939-B1 (NL)
Title: A solar panel and method for increasing safety and reliability of a solar panel
Inventor: ING PETRUS PAULUS CAROLUS MARIA STASSEN
IPC: H02S50/00
Filed: 2016-06-21
Granted: 2018-01-04
Abstract: A solar panel comprising at its front side a transparent plate and behind said transparent plate a number of photo voltaic cells. The solar panel comprises a strip (7) of electric conductive material surrounding, in front view, one or more of said photovoltaic cell. Said strip (7) of electric conductive material is connected with the lower or higher electric potential of said string, or with earth, or with an external electric potential.
Patent NL-1042058-B1 (NL)
Title: Sieraad
Inventor: CORSTIAAN JOHANNES VAN GOOLEN
IPC: A44C9/00
Filed: 2016-09-12
Granted: 2018-03-20
Abstract: De uitvinding heeft betrekking op een draagbaar sieraad voor de vinger, arm/polsband, halsketting, oorbellen wat geheel uit elementen bestaat en onderling met elkaar uitwisselbaar en passend is. Met name de ring heeft de eigenschap dat deze met één en dezelfde maatvoering van de midden ring uitwisselbaar is en veranderd kan worden van breedte, kleur en/of model 10 zonder dat de gehele ring vervangen behoeft te worden. Omdat de beide uiteinden op maat van de gebruikster/gebruiker zijn en dus èènmalig aangeschaft dient te worden terwijl het toch passend is op de midden ring die voor alle maten/dikten van vingers èèn gelijke maatvoering heeft. Het uitgekiende schroefdraad systeem en de positie van het schroefdraad maken het mogelijk dat alle elementen van zowel de ring als armband als halsketting en oorbellen passend zijn en naar gelang van gewenste look uit te breiden en aan te passen zijn op de gehele sieradenlijn.
Patent NL-1042973-B1 (NL)
Title: Inrichting en Werkwijzen voor het in de Grond Drukken of uit de Grond Trekken van Langwerpige Constructie-elementen
Inventor: PETER VAN HALTEREN JR
IPC: E02D11/00
Filed: 2018-08-29
Granted: 2020-05-29
Abstract: De uitvinding heeft betrekking op een inrichting (50), een systeem (10), en werkwijzen voor het indrukken van een langwerpig constructie-element (34), zoals een paal, buis, of wanddeel, in een grondlaag (30), en/of voor het uittrekken van het langwerpige constructie- element uit de grondlaag, onder gebruikmaking van een aantal langwerpige hulpelementen (40) die in de grondlaag (30) worden geplaats voor het genereren van reactiekrachten.
Patent NL-1043986-B1 (NL)
Title: Verbeterde inrichting voor het inspecteren van de onderzijde van een voertuig
Inventor: CORNELIS GERARDUS THEODORUS VINK
IPC: H04N7/18
Filed: 2021-04-07
Granted: 2022-10-19
Abstract: De onderhavige uitvinding heeft betrekking op een verbeterde inrichting voor de inspectie van de onderzijde van voertuigen met onder meer het doel explosieven te kunnen detecteren ter voorkoming van terroristische aanslagen. Naast de voornoemde toepassing leent het systeem zich ook uitstekend voor het bij grensovergangen detecteren van bij voorbeeld onder voertuigen verstopte smokkelwaar of het bij de poort van een bedrijf uitvoeren van een controle op pogingen tot diefstal van eigendommen van het bedrijf. 1043986
Patent NL-2013323-B1 (NL)
Inventor: PASCAL JOHANNA THEODORUS MARIA HIEL
IPC: H04W4/90
Filed: 2014-08-12
Granted: 2016-09-21
Abstract: De uitvinding heeft betrekking op een meetapparaat, omvattend: - een sensor, voor het meten van de waarde van een parameter; - een baken, voor het verzenden van een aanwezigheidssignaal met al dan niet een communicatie-verzoek naar communicatie-inrichtingen; en - communicatiemiddelen voor het realiseren van een verbinding met een communicatie-inrichting op basis van een reactie van de communicatie-inrichting op het aanwezigheidssignaal of het communicatie-verzoek en voor het verzenden van informatie op basis van de gemeten waarde van de parameter naar de communicatie-inrichting.
Patent NL-2019427-B1 (NL)
Title: Running a subsea riser string.
Inventor: PIETER DIRK MELIS VAN DUIVENDIJK
IPC: E21B19/00
Filed: 2017-08-18
Granted: 2019-02-25
Abstract: Vessel adapted to perform subsea wellbore related operations, involving a riser string that extends between a subsea wellbore and a vessel and that is assembled from releasably interconnected riser sections that each comprise a main riser pipe and at least one auxiliary pipe, vessel comprising an auxiliary pipe filling device adapted to fill the at least one auxiliary pipe of a riser section during a lowering step of said riser running operation, the auxiliary pipe filling device comprising a liquid source, e.g. for water, at least one nozzle adapted to dispense water into said auxiliary pipe, a liquid flow line, connecting the liquid source with the nozzle, and a nozzle mount that is adapted to mount the nozzle in a filling position in which the nozzle is positioned to dispense liquid into the at least one auxiliary pipe of the riser section during said lowering step.
Patent NL-2021908-B1 (NL)
Title: A torque sensing system
Inventor: BAS JAN EMILE VAN RENS
IPC: B01L3/10
Filed: 2018-10-31
Granted: 2020-05-14
Abstract: A torque sensing system is described comprising: a rotatable shaft having a first part and a second part, the shaft comprising a deformable spring structure between the first and second part; a first readout structure connected to the first part comprising a plurality of first position indicators and a second readout structure connected to the second part comprising a plurality of second position ndicators; an encoder system configured to measure a first rotatory position of the first part of the shaft based on the plurality of first position indicators and a first reference indicator and a second rotary position based on the plurality of second position indicators and a second reference ndicator; and, wherein in response to a first torque applied to the first part and a second torque applied to the second part, the second torque having direction opposite to the first torque, the spring structure providing a relative shift in the rotary position between the first and second part, the first and second absolute rotary position measured by the encoder system defining an angle of twist of the shaft.
Patent NL-2025734-B1 (NL)
Title: Combined type mouse-stopping device capable of adjusting the tilt angle
Inventor: CAIXIA HAO
IPC: A01M29/30
Filed: 2020-06-03
Granted: 2021-09-21
Abstract: This invention provides a tilt angle adjustable combined rat-proof device, relating to the technical ﬁeld of rat-proof devices. A rat-proof device includes a rat-proof plate body, a ﬁxing mechanism and an adjusting mechanism, wherein the rat-proof plate body is inserted into the ﬁxing mechanism 5 so that the rat-proof plate body is able to be clamped, and an upper end of the ﬁxing mechanism is clamped into the adjusting mechanism and is able to slide along the adjusting mechanism so as to drive the rat-proof plate body to move, thereby realizing adjustment of the tilt angle of rat-proof plate body. The device can adjust the tilt angle based on the user’s actual requirements, therefore adapting to the use environment, and it is also extremely convenient in the process of transportation, 10 disassembly and installation.
Patent NL-2029510-B1 (NL)
Title: Modular Mobile Work Apparatus
Inventor: LEENDERT WILHELMUS CORNELIS HUISSOON
IPC: B60K17/28
Filed: 2021-10-26
Granted: 2023-05-23
Abstract: Mobile apparatus comprising a main-frame (1) with displacing means (2) configured to displace the mobile apparatus; a rotating sub-frame (4) rotatably connected to the main-frame, such that the 5 sub-frame is rotatable relative to the main frame; a working arm (567) connected to the sub-frame, wherein the main-frame and/or the sub-frame comprises a plurality of modules respectively comprising energy storage means configured for storing energy; energy transformation means for transforming energy to electrical energy; power train means for driving the displacing means; wherein the modules are connectable through any one of a high voltage, low voltage or bus control 10 system or a combination thereof and wherein the modules are removably mountable. FIG. 1A
Patent NL-2029949-B1 (NL)
Title: Compound enzyme hair-washing and conditioning lotion
Inventor: YUCHENG CHEN
IPC: A61Q5/12
Filed: 2021-11-29
Granted: 2023-06-19
Abstract: The present disclosure provides a compound enzyme hair-washing and conditioning lotion. The present disclosure performs enzyme fermentation and liquid-solid separation of a obtained fermentation liquid to obtain a clear solution as the compound enzyme hair-washing and conditioning lotion. The compound enzyme hair-washing and conditioning lotion is capable of replacing the traditional chemical shampoo, and has ecological safety, use and hair protection effects, which is suitable for use as the enzyme shampoo and conditioner or skin care lotion.
Patent NL-2031615-B1 (NL)
Title: Absorption medium and method for carbon dioxide absorption from flue gas
Inventor: HERMANUS KLEIN TEESELINK
IPC: B01D53/14
Filed: 2022-04-19
Granted: 2023-11-06
Abstract: The invention relates to an absorption medium for the absorption of carbon dioxide from flue gas, wherein said adsorption medium is an amine based absorption medium. The invention also relates to a method and system making use of such absorption medium.
Patent NL-2034633-B1 (NL)
Title: High-efficiency quick multi-enzyme cleaning solution prepared by continuous flow micro-channel reaction device
Inventor: YIRAN CHEN
IPC: C11D11/00
Filed: 2023-04-19
Granted: 2023-11-16
Abstract: Disclosed is a method for preparing a high-efﬁciency quick multi-enzyme cleaning solution by a continuous ﬂow micro-channel reaction device, which comprises: dissolving a multi-enzyme composition, a stabilizing agent, a defoaming agent and an anti-freezing agent in deionized water to prepare a multi-enzyme concentrated solution A, dissolving lysozyme and a sterilizing agent in 10 deionized water to prepare a mixed cleaning solution B, and respectively and simultaneously pumping the multi-enzyme concentrated solution A and the mixed cleaning solution B into a micro-mixer of the continuous ﬂow micro-channel reaction device, and then making the mixture ﬂow into a micro-reactor for sufﬁcient mixing to obtain the multi-enzyme cleaning solution. Compared with a traditional cleaning solution, the multi-enzyme cleaning solution is creatively 15 prepared by the micro-channel reaction device in the invention, the multi-enzyme cleaning solution is fully mixed in a micro-channel, without needing to add an additional surfactant, the multi-enzyme cleaning solution realizes cleaning while ﬂowing, which is simple and quick, and shortens a cleaning time, meanwhile, a usage amount of the multi-enzyme cleaning solution is controlled at any time, thus saving a cleaning cost, and simultaneously prolonging a service time of 20 the multi-enzyme cleaning solution, so that the multi-enzyme cleaning solution is fully utilized, which reduces a loss of an instrument caused by cleaning, and reduces a medical cost.
Patent RO-111542-B1 (RO)
Title: Stabilized pharmaceutical composition
Inventor: MOHAN B KABADI
IPC: A61K9/08
Filed: 1992-12-10
Abstract: A pharmaceutical dosage form comprising an HMG-CoA reductase inhibitor compound, e.g., fluvastatin sodium, is disclosed which is stabilized against pH-related degradation by an alkaline stabilizing medium capable of imparting a pH of at least 8 to an aqueous solution or dispersion of the composition.
Patent RO-113694-B1 (RO)
Inventor: RîNEA TIBERIU EMIL
IPC: H03K17/56
Filed: 1993-02-24
Abstract: Invenţia se referă la comutaţia - adică conectarea şi deconectarea - de la o sursă a consumatorilor care absorb energie reactivă, cu sau fără absorbţie şi de energie activă, care pune problemele desupracurent la conectare şi de putere de rupere şi supratensiuni interne la deconectare. Înţelegând oscilaţia alternativă (balansul) de energie reactivă între sursă şi consumator şi inerţia fenomenului, s-a elaborat o schemă dezvoltată cu tiristoare şi s-a adoptat comutaţia precisă în raport cu undele tensiune/curent şi s-a făcut alegerea optimă a momentelor şi succesiunea manevrelor. Metoda permite diminuarea/anularea şocurilor de curent şi supratensiunile interne, dar şi reglajul puterii consumatorului sau diferite protecţii. Interesează pentru comutarea tuturor consumatorilor cum ar fi motoarele de 1-25.000 KW şi trafo de 1-1000.000 KVA, de joasă sau înaltă tensiune.
Patent RO-112883-B1 (RO)
Inventor: CALOIANU MARIA
IPC: C05G3/00
Filed: 1996-05-15
Abstract: Invenția se referă la o compoziție
de hidrogeluri bioartificiale cu higroscopicitate
avansată, care reprezintă un material
compozit constituit dintr-un hidrolizat de
colagen cu masa moleculară medie de 5... 20
kDa, un copolimer de anhidridă maleică și un
alt comonomer ales între: stiren, acetat de
vinii, acriionitril, metil metacrilat, acid acrilic,
2-hidroxi-etil acrilat, acrii amidă sau vinii
pirolidonă, cu masa moleculară medie de 5...
50 kDa, glicerină și restul apă, destinat
realizării unor suprafețe vegetale naturale, în
spații închise, pe terenuri aride și din zone
deșertice, temporare sau permanente.
Revendicări: 1
Patent RO-117793-B1 (RO)
Title: Pyridonecarboxylic acid derivatives and pharmaceutical composition containing the same
Inventor: TOMITA KYOJI
IPC: A61P35/00
Filed: 1995-06-06
Abstract: The invention relates to pyridonecarboxylic acid derivatives having a structure corresponding to the general formula (I):, wherein R1 is a hydrogen atom, a lower alkoxy group, a halogen atom, a lower alkyl group which may be substituted with a halogen atom or a phenyl group which may be substituted with a halogen atom; R2 is a carboxyl group or a group convertible to a carboxyl group; R3 is a hydrogen atom, an amino group which may be protected, a halogen atom or a lower alkyl group which may be substituted with a halogen atom; A is CH; m is an integer : 1 or 2, and Y is a cleavable group, as well as to the salts thereof, said derivatives being used as antitumor agents, and to a pharmaceutical composition containing the same.