Patent GB-357721-A (GB)
Title: A process for introducing active oxygen into organic compounds
IPC: C07F9/09
Filed: 1930-08-11
Abstract: Stable products capable of evolving oxygen are obtained by using hydrogen-peroxide-phosphate compounds as agents for introducing active oxygen into readily oxidizable organic compounds such as menthol, menthone, paraformaldehyde or thymol. Particularly stable products are obtained when the perphosphates employed are themselves very durable, such as those containing 2 mols. of hydrogen peroxide to 2 mols. of disodium phosphate or to 1 mol. of pyrophosphate.  Such a body may be obtained by mixing a slight excess of 30 per cent hydrogen peroxide with crystallized sodium pyrophosphate, excess of peroxide being removed, e.g. by vacuum distillation; the perphosphates are then dehydrated by heating.  The constituents of the addition products may be employed in stoichiometric proportions, e.g. 1 mol. of formaldehyde to perphosphate equivalent to 1 mol. of hydrogen peroxide, or excess of either constituent may be used.  The individual constituents may be brought together in dry solid form, or may be partly solid and partly liquid, and small quantities of dissolving or emulsifying substances may be used, and these may be removed subsequently.  Another method of procedure is to treat the organic substance with a suitable mixture of hydrogen peroxide and phosphate, for example a mixture containing a slight excess of hydrogen peroxide.  A mixture containing suitable organic compounds, e.g. a mixture containing inert constituents as well as those having an antiseptic action, may also be treated in this way.  The products may be worked up, if desired with the addition of fillers, or of substances promoting solubility such as dextrose, to tablets, powders, pastes, creams or salves.ALSO:Stable products capable of evolving oxygen are obtained by using hydrogen peroxide-phosphate compounds as agents for introducing active oxygen into readily oxidizable organic compounds such as menthol, menthone, paraformaldehyde or thymol. Particularly stable products are obtained when the perphosphates employed are themselves very durable, such as those containing 2 mols. of hydrogen peroxide to 2 mols. of disodium phosphate or to 1 mol. of pyrophosphate.  Such a body may be obtained by mixing a slight excess of 30 per cent hydrogen peroxide with crystallized sodium pyrophosphate, excess of peroxide being removed e.g. by vacuum distillation; the perphosphates are then dehydrated by heating.  The constituents of the addition products may be employed in stoichiometric proportions, e.g. 1 mol. of formaldehyde to perphosphate equivalent to 1 mol. of hydrogen peroxide, or excess of either constituent may be used.  The individual constituents may be brought together in dry solid form, or may be partly solid and partly liquid, and small quantities of dissolving or emulsifying substances may be used, and these may be removed subsequently.  Another method of procedure is to treat the organic substance with a suitable mixture of hydrogen peroxide and phosphate, for example a mixture containing a slight excess of hydrogen peroxide.  A mixture containing suitable organic compounds, e.g. a mixture containing inert constituents as well as those having an antiseptic action, may also be treated in this way.  The products may be worked up, if desired with the addition of fillers, or of substances promoting solubility such as dextrose, to tablets, powders, pastes, creams or salves.ALSO:Stable products capable of evolving oxygen are obtained by using hydrogen-peroxide-phosphate compounds as agents for introducing active oxygen into readily oxidizable organic compounds such as menthol, menthone, paraformaldehyde or thymol. Particularly stable products are obtained when the perphosphates employed are themselves very durable, such as those containing 2 mols. of hydrogen peroxide to 2 mols. of disodium phosphate or to p  1 mol. of pyrophosphate.  Such a body may be obtained by mixing a slight excess of 30 per cent hydrogen peroxide with crystallized sodium pyrophosphate, excess of peroxide being removed, e.g. by vacuum distillation; the perphosphates are then dehydrated by heating.  The constituents of the addition products may be employed in stoichiometric proportions, e.g. 1 mol. of formaldehyde to perphosphate equivalent to 1 mol. of hydrogen peroxide, or excess of either constituent may be used.  The individual constituents may be brought together in dry solid form, or may be partly solid and partly liquid, and small quantities of dissolving or emulsifying substances may be used, and these may be removed subsequently.  Another method of procedure is to treat the organic substance with a suitable mixture of hydrogen peroxide and phosphate, for example a mixture containing a slight excess of hydrogen peroxide.  A mixture containing suitable organic compounds, e.g. a mixture containing inert constituents as well as those having an antiseptic action, may also be treated in this way.  The products may be worked up, if desired with the addition of fillers, or of substances promoting solubility such as dextrose, to tablets, powders, pastes, creams or salves.