baber/WOPTO huggingface dataset:
Patent CA-2496319-A1 (CA)
Title: Mammalian megakaryocyte progenitor cell
Inventor: WEISSMAN IRVING L
IPC: A61K35/28
Filed: 2003-09-12
Abstract: A substantially enriched mammalian hematopoietic cell population is provided, which is characterized as a progenitor cell committed to the megakaryocyte lineage. Methods are provided for the isolation and culture of these cells.  The cell enrichment methods employ reagents that specifically recognize CD9 and CD41, in conjunction with other markers expressed on lineage committed progenitor cells. These cells give rise exclusively to megakaryocytes and platelets, as evidenced by their growth and differentiation in vitro and in vivo.
Patent CA-2499998-A1 (CA)
Inventor: WITTORFF HELLE
IPC: A23G4/02
Filed: 2003-09-24
Abstract: The invention relates to chewing gum comprising at least two different biodegradable polymers. According to the invention, a chewing gum comprising at least two different biodegradable polymers exhibits an improved texture prior to any adding of for example softeners. It has been realized that the desired chewing gum texture properties, contrary to every expectation and an y prior art disclosures, may actually be obtained when combining biodegradable chewing gum polymers, for example in the gum base or in the final gum.</SDOA B>
Patent CA-2500717-A1 (CA)
Title: Modular solarium
Inventor: THERRIEN MARTIAL
IPC: E04H15/00
Filed: 2005-04-18
Abstract: A solarium including a plurality of modules that can be assembled at different angles and positions using flexible junctions. The modules are assembled so as 5to allow disassembly in order to easily change the dimensions and shape of the solarium.
Patent CA-2501248-A1 (CA)
Inventor: ARNOLD JOHN G JR
IPC: F23L17/02
Filed: 2005-03-18
Abstract: Coiffe pour l'orifice d'évacuation d'une cheminée, destinée à améliorer l'extraction de la fumée et à fournir une protection contre l'entrée d'animaux et de débris. La coiffe comprend des parois latérales constituées de tôle métallique plate formant un boîtier tubulaire, un sommet fixé aux parois latérales par des attaches, plusieurs ouvertures à lames dans une partie inférieure des parois latérales afin d'aspirer l'air et plusieurs ouvertures d'évacuation situées dans une partie supérieure des parois latérales, au-dessus des ouvertures à lames. Les ouvertures d'évacuation sont du moins égales à une superficie de la section transversale de l'orifice d'évacuation. Les parois latérales ont une partie non perforée entre les parties inférieure et supérieure. Un ensemble interne d'armature et de montage est fixé au bord inférieur de chaque paroi latérale. Des moyens d'ancrage et de nivellement ancrent l'ensemble de montage et d'armature à la cheminée et mettent la coiffe au niveau de la cheminée.
Patent CA-2502057-A1 (CA)
Title: Bracket assembly for securing mirrors to walls
Inventor: BOUCHARD ANDRE
IPC: F16B13/04
Filed: 2005-03-21
Abstract: A bracket assembly for mounting mirrors to walls comprises a bracket and an anchor. The anchor includes a threaded stem for securing the anchor to the wall and a connector adapted to protrude outwardly of the wall when the anchor is mounted to the wall. The bracket includes a socket adapted to receive the connector and an arm for bearing against the mirror and holding the same against the wall. The socket and the connector include cooperating locking elements. Once the anchor has been installed to the wall via the threaded stem, the socket is engaged over the connector so as to secure the bracket to the anchor via the locking elements with the bracket concealing the anchor. The mirror is held between the arm and the wall. The connector defines knurls that engage a skirt in the socket thereby providing a plurality of locking positions along an axis of the anchor, whereby a distance between the arm and the wall can be varied to accommodate mirrors of various thicknesses. The locking elements are also adapted to prevent the bracket from rotating relative to the anchor about the axis thereof.
Patent CA-2502320-A1 (CA)
Inventor: CHANG SOU-JEN
IPC: A61K31/401
Filed: 2003-10-22
Abstract: The present invention relates to the use of compounds of formula (I) for the treatment of epilepsy, bipolar disorder, psychiatric disorders, migraine, pain, or movement disorders, and to provide neuroprotection.
Patent CA-2504537-A1 (CA)
Inventor: ATHALYE SANJEEV ARVIND
IPC: H04L12/18
Filed: 2004-09-13
Abstract: A method and a system for providing signaling in cellular telephone system providing broadcast services to fully integrate broadcast services with the services provided by the cellular telephone systems. The signaling method coordinate interaction between an access network and the subscriber station to allowing the subscriber station to decode the broadcast service, to receive paging messages while receiving the broadcast service, to properly transitio n between operation states, and other functions known to one of ordinary skill in the art.
Patent CA-2504919-A1 (CA)
Title: System of layers for transparent substrates and coated substrate
Inventor: IHLO LARS
IPC: C03C17/245
Filed: 2002-11-07
Abstract: The invention relates to a system of layers for coating the surface of transparent substrates, in particular, a system of layers with low emissivity (Low-E) for glass windows, comprising at least one layer of mixed oxides produced by reactive cathodic sputtering from a metallic target alloy. The mixed oxide layer comprises ZnO, Ti0¿2? and at least one of the oxides Al¿2?0¿3?, Ga¿2?0¿3? and Sb¿2?0¿3? and finds application as upper and/or lower anti-reflection layer, partial layer of an anti-reflecting layer and/or a final finishing layer. Said system of layers is characterised by a high degree of hardness and excellent resistance to the maritime climate.
Patent CA-2505590-A1 (CA)
Title: Bis-aryl sulfonamides
Inventor: WRIGHT J J
IPC: C07D213/74
Filed: 2003-11-18
Abstract: Compounds are provided that act as potent antagonists of chemokine receptors . The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of chemokine receptor - mediated diseases, and as controls in assays for the identification of chemokine antagonists.
Patent CA-2509058-A1 (CA)
Title: Administration de cellules dendritiques partiellement matures in vitro pour le traitement de tumeurs
Inventor: BOSCH MARNIX L
IPC: A61K39/00
Filed: 2003-12-05
Abstract: L'invention concerne des populations de cellules comprenant des cellules dendritiques partiellement matures pouvant être administrées à des individus présentant une tumeur. Les cellules dendritiques partiellement matures, celles mises en contact avec un agent de maturation de cellule dendritique pendant environ 1 à environ 10 heures, ou plus, fixent et traitent de manière efficace des antigènes tumoraux dans la zone du site de la tumeur, achèvent leur maturation, et peuvent ensuite migrer dans les ganglions lymphatiques d'un individu traité. Une fois dans le ganglion lymphatique, les cellules dendritiques pleinement matures présentant l'antigène sécrètent les cytokines appropriées (par exemple, TNF.alpha. and IL-12), et entrent en contact avec des lymphocytes T, induisant une réponse immunitaire anti-tumorale sensible.
Patent CA-2509719-A1 (CA)
Title: Method and apparatus for providing on-demand hot water
Inventor: COLLENS STEPHEN T
IPC: F28D9/00
Filed: 2005-06-10
Abstract: Waste heat from a steam cycle employing a steam boiler is used to heat water, on an on-demand basis, in a steam-to-water heat exchanger wherein the supply of steam into the heat exchanger is regulated so as to maintain the temperature of the heated water exiting the heat exchanger at a relatively constant pre-set temperature. Further waste heat may be recaptured .from the steam boiler steam cycle by pre-heating the incoming cold water being fed into the steam-to-water heat exchanger in the on-demand water heater using the still-hot condensate from the condensation of the steam in the steam-to-water heat exchanger. A condensate-to-water heat exchanger may be employed to pre-heat the cold water infeed to the steam-to-water heat exchanger.
Patent CA-2510310-A1 (CA)
Inventor: CANDAU DIDIER
IPC: A61Q19/00
Filed: 2005-06-21
Abstract: La présente invention est relative à un procédé de photostabilisation vis-à- vis du rayonnement UV d'au moins un dérivé du dibenzoylméthane par au moins un dérivé arylalkyl benzoate et au moins un composé bis-résorcinyl triazine. Un autre objet de l'invention concerne également une nouvelle compositi on cosmétique ou dermatologique, à usage topique, caractérisée par le fait qu'elle comprend au moins, dans un support cosmétiquement acceptable : (a) au moins un filtre UV du type dérivé du dibenzoylméthane et (b) au moins un dérivé arylalkyl benzoate et (c) au moins un composé bis-résorcinyl triazine. La présente invention a également pour objet l'utilisation d'un dérivé arylalkyl benzoate et d'un composé bis-résorcinyl triazine dans une composition cosmétique ou dermatologique comprenant au moins un dérivé du dibenzoylméthane dans le but de d'améliorer la stabilité vis-à-vis des rayon s UV dudit dérivé de dibenzoylméthane.
Patent CA-2510713-A1 (CA)
Inventor: LI XIANMING JIMMY
IPC: F23Q3/00
Filed: 2005-06-27
Abstract: Système de combustion comprenant un four ayant une charge thermique et une atmosphère de combustion disposées dans celui-ci; une ou plusieurs lances à carburant conçues pour injecter du carburant dans l'atmosphère de combustion; et un ou plusieurs allumeurs associés à une ou plusieurs lances de carburant et conçus pour allumer le carburant injecté par une ou plusieurs lances à carburant dans l'atmosphère de combustion.
Patent CA-2511997-A1 (CA)
Title: Mitigating denial of service attacks
Inventor: MADHANI SUNIL
IPC: H04L29/06
Filed: 2004-01-27
Abstract: Service attacks, such as denial of service and distributed denial of service attacks, of a customer network are detected and subsequently mitigated by the Internet Service Provider (ISP) that services the customer network. A sensor examines the traffic entering the customer network for attack traffic. When an attack is detected, the sensor notifies an analysis engine within the ISP  network to mitigate the attack. The analysis engine configures a filter router to advertise new routing information to the border and edge routers of the ISP  network. The new routing information instructs the border and edge routers to reroute attack traffic and non-attack traffic destined for the customer network to the filter router. At the filter router, the attack traffic and non-attack traffic are automatically filtered to remove the attack traffic. The non-attack traffic is passed back onto the ISP network for routing towards the customer network.
Patent CA-2514918-A1 (CA)
Title: Method to confer cell culture replication activity to different hepatitis c virus isolates
Inventor: MARKEL ERIC J
IPC: C12N7/02
Filed: 2004-02-09
Abstract: The present invention features methods for producing HCV replicons using HCV  encoding sequences from different isolates. The featured methods are based on the discovered importance of NS3 amino acid position 470 in conferring cell culture replication activity to different HCV isolates.
Patent CA-2518653-A1 (CA)
Inventor: BOULGAKOVA ADILIA
IPC: A41D3/08
Filed: 2005-09-09
Abstract: A blanket structure purposed for facilitating the warmth of an user has a main body dimensioned substantially to receive a user or a support surface. The blanket comprises at least one primary drawstring disposed along a periphery of the main body whereby the primary drawstring can be tightened to form a primary pocket in the main body. An auxiliary body is releasably attached to the main body at a position substantially opposite to the primary drawstring. At least one secondary drawstring is disposed along a periphery of the auxiliary body, the arrangement being such that the primary and secondary drawstrings can be tightened to form primary and secondary pockets in the main body and the auxiliary body, respectively.
Patent CA-2518719-A1 (CA)
Inventor: BABA AKIRA
IPC: B31B7/00
Filed: 2004-02-25
Abstract: Method of fabricating containers made from a cardboard or corrugated paperboard blank (17) having an inner liquid holding bag (11) secured to the inner surface of the paperboard box. The liquid holding bag (11) includes a spout (16) that extends through a spout opening (19) formed in the paperboar d blank (17). During the fabrication process the spout (16) is utilized to precisionally locate the liquid holding bag (11) so that when the panel of t he blank (17) with the spout opening (19) is folded down over the spout (16), t he spout (16) will be properly aligned with the spout opening (19) thus facilitating the automatic assembly of the container. In this automatic assembly process the liquid holding bag (11) is secured to the inner surface of the container at multiple locations such that when the container is opene d into its three dimensional use configuration a passage is opened for filling the bag (11) through the spout (16).
Patent CA-2521534-A1 (CA)
Title: Microfluidic analytical system with accessible electrically conductive contact pads
Inventor: MACLENNAN MARGARET
IPC: G01N27/00
Filed: 2005-09-28
Abstract: A microfluidic analytical system for monitoring an analyte (such as glucose) in a fluid sample (e.g., blood or ISF) includes an analysis module and an electrical device (for example, a meter or power supply). The analysis module includes an insulating substrate and a microchannel(s) within the insulating substrate's upper surface. The analysis module also includes a conductive contact pad(s) disposed on the upper surface of the insulating substrate and an electrode(s), with the electrode(s) being disposed over the microchannel. In addition, the analysis module includes an electrically conductive trace(s) that electrically connects the electrode to at least one electrically conductive contact pad. The analysis module also has a laminate layer disposed over the electrode, the electrically conductive trace, the microchannel and a portion of the upper surface of the insulating substrate. The electrically conductive contact pad of the analysis module has an accessible exposed surface for electrical connection to the electrical device.
Patent CA-2522766-A1 (CA)
Title: Surgical hand access apparatus
Inventor: WENCHELL THOMAS
IPC: A61B17/34
Filed: 2004-04-26
Abstract: A hand access device (100) includes a housing (102) defining a longitudinal axis and having a passageway therethrough dimensioned to permit passage of a surgeon~s arm and a fabric seal (104) mounted within the opening and being dimensioned to form a substantial sealing relation with the surgeon's arm. The fabric seal (104) is elongated extending along the longitudinal axis and may define a general hour glass configuration. A pair of flexible bands (12) may be mounted about the fabric seal. The flexible bands (112) are adapted to engage an outer surface of the seal to bias the fabric seal (104) to a closed position thereof.
Patent CA-2524334-A1 (CA)
Inventor: KONIECZYNSKI DAVID D
IPC: A61B17/70
Filed: 2004-06-10
Abstract: The present invention generally provides a polyaxial fixation device having a shank with a spherical head formed on a proximal end thereof, and a receiver member having an axial passage formed therein that is adapted to polyaxially seat the spherical head of the shank. The polyaxial bone screw further includes an engagement member that is adapted to provide sufficient friction between the spherical head and the receiver member to enable the shank to be maintained in a desired angular orientation before locking the spherical head within the receiver member.
Patent CA-2526343-A1 (CA)
Title: Ancestral viruses and vaccines
Inventor: ROSS HOWARD A
IPC: C07K14/16
Filed: 2004-05-19
Abstract: The present invention is directed to ancestral HIV and FIV nucleic acid and amino acid sequences, methods for producing such sequences and uses thereof, including prophylactic and diagnostic uses.
Patent CA-2527323-A1 (CA)
Title: Methods for predicting drug efficacy in patients afflicted with hypertension
Inventor: HAKONARSON HAKON
IPC: A61K31/401
Filed: 2004-06-04
Abstract: Methods are disclosed for predicting the efficacy of a drug for treating hypertension in a patient, including: obtaining a sample of cells from the patient; obtaining a gene expression profile from the sample in the absence and presence of in vitro modulation of the cells with specific mediators; and comparing the gene expression profile of the sample with a reference gene expression profile, wherein similarity between the sample expression profile and the reference expression profile predicts the efficacy of the drug for treating hypertension in the patient.
Patent CA-2529436-A1 (CA)
Title: Derives de pyrazolidinedione
Inventor: VALDENAIRE OLIVER
IPC: C07C45/00
Filed: 2004-06-16
Abstract: L'invention concerne des dérivés de pyrazolidinédione de formule générale (I), dans laquelle R¿1? désigne un hydrogène, un alkyle éventuellement substitué, un cycloalkyle, un aryle, un arylalkyle, un hétéroaryle, un hétéroarylalkyle ou un alkanoyle; et R¿2? représente un aryle ou un hétéroaryle; des tautomères de ceux-ci; des isomères géométriques de ceux-ci et des tautomères de ces isomères géométriques, notamment des mélanges de composés individuels de formule (I), ou des tautomères de ceux-ci, et des isomères géométriques de ceux-ci ou des tautomères de ceux-ci, des sels d'ajout acides acceptables sur le plan pharmaceutique des composés qui sont basiques; des sels acceptables sur le plan pharmaceutique de composés renfermant des groupes acides avec des bases; des esters acceptables sur le plan pharmaceutique des composés renfermant des groupes hydroxy ou carboxy; des promédicaments de composés dans lesquels un groupe formant un promédicament est présent; ainsi que des hydrates ou solvates de ceux-ci; lesdits dérivés sont actifs comme antagonistes du récepteur de l'adénosine diphosphate des plaquettes et peuvent être utilisés pour la prévention et/ou le traitement de maladies vasculaires périphériques, vasculaires viscérales, hépatiques et rénales, cardio-vasculaires et cérébro-vasculaires ou d'états associés à l'agrégation plaquettaire, notamment la thrombose et, respectivement, pour la fabrication des médicaments correspondants. Quelques composés, mais pas tous, de la formule (I) susmentionnée sont nouveaux.
Patent CA-2530649-A1 (CA)
Title: Antiepileptic agent
Inventor: ICHIKAWA SHUNJI
IPC: A61K31/522
Filed: 2004-06-25
Abstract: An antiepileptic agent which contains either a xanthine derivative represented by the formula (I): (I) (wherein R1, R2, and R3 are the same or different and each represents hydrogen, lower alkyl, lower alkenyl, or lower alkynyl;  R4represents cycloalkyl, -(CH2)n.cndot.R5, or the formula (II); (II) and X1 and X2 are the same or different and each represents oxygen or sulfur) or a pharmacologically acceptable salt thereof as an active ingredient.
Patent CA-2531149-A1 (CA)
Title: Ultra-stable composition comprising natural oil and their derivatives and uses thereof
Inventor: KLEIMAN ROBERT
IPC: A61Q19/08
Filed: 2003-10-31
Abstract: Compositions comprising long-chain organic molecules obtained from natural oils, particularly plant, bean, seed and nut oils, and their derivatives can be provided with increased oxygen stability by their combination with mixtures of particular classes of antioxidants, particularly combinations of at least one synthetic free-radical terminating antioxidant. The stabilization combination is particularly effective in combination with long-chain oils having less than 5% methylene interrupted unsaturation. The long-chain oil may comprise a natural oil or wax. The long-chain oil may have a percent methylene interrupted unsaturation of less than 5%, less than 3%, or less than 1%. The emollient composition may have at least one supplemental additive, which is a reducing agent present in an amount of from 0.01 to 5% or more by weight of said long-chain oil and the free-radical terminating antioxidant is present in an amount of from 0.01 to 5% by weight of said long-chain oil. The composition preferably has the long-chain oil selected from the class consisting of Macadamia oil and its derivatives, Moringa oil and its derivatives, Babassu oil and its derivatives, and Meadowfoam and its derivatives, High Oleic Sunflower, and having a percentage methylene interrupted unsaturation of less than 5.
Patent CA-2531634-A1 (CA)
Title: Compact high power alternator
Inventor: LAFONTAINE CHARLES Y
IPC: H02K7/09
Filed: 2004-07-12
Abstract: An apparatus for converting between mechanical and electrical energy, particularly suited for use as a compact high power alternator for automotiv e use and "remove and replace" retrofitting of existing vehicles. The apparatu s comprises a rotor with permanent magnets, a stator with a winding, and a cooling system. Mechanisms to prevent the rotor magnets from clashing with t he stator by minimizing rotor displacement, and absorbing unacceptable rotor displacement are disclosed. The cooling system directs coolant flow into thermal contact with at least one of the winding and magnets, and includes a t least one passageway through the stator core. Various open and closed coolin g systems are described. Cooling is facilitated by, for example, loosely wrapping the winding end turns, use of an asynchronous airflow source, and/or directing coolant through conduits extending through the stator into thermal contact with the windings.
Patent CA-2533549-A1 (CA)
Title: Variable direction of view instrument with distal image sensor
Inventor: HALE ERIC L
IPC: G02B23/00
Filed: 2006-01-20
Abstract: A viewing instrument having a variable direction of view is disclosed generally comprising a shaft, a sensor mounted in the distal end of the shaft such that the image plane of the sensor is substantially parallel to the longitudinal axis of the shaft, and a reflecting element that rotates about an axis substantially perpendicular to the longitudinal axis of the shaft. In some embodiments, a negative lens is mounted adjacent the reflecting element, and in certain embodiments, a positive lens is positioned adjacent the image sensor.
Patent CA-2534585-A1 (CA)
Title: Human anti-ngf neutralizing antibodies as selective ngf pathway inhibitors
Inventor: WILD KENNETH D JR
IPC: C12N15/68
Filed: 2004-07-15
Abstract: This invention provides antibodies that interact with or bind to human nerve growth factor (NGF) and neutralize the function of NGF thereby. The invention also provides pharmaceutical compositions of said antibodies and methods for neutralizing NGF function, and particularly for treating NGF-related disorders (e.g., chronic pain) by administering a pharmaceutically effective amount of anti-NGF antibodies. Methods of detecting the amount of NGF in a sample using anti-NGF antibodies are also provided.
Patent CA-2535808-A1 (CA)
Inventor: KADYK LISA
IPC: A61K/
Filed: 2004-08-12
Abstract: Human MELK genes are identified as modulators of the RAC pathway, and thus are therapeutic targets for disorders associated with defective RAC function.  Methods for identifying modulators of RAC, comprising screening for agents that modulate the activity of MELK are provided.
Patent CA-2536929-A1 (CA)
Title: 2-substituted benzimidazole piperidines analogs as selective melanin concentrating hormone receptor antagonists for the treatment of obesity and related disorders
Inventor: GUO TAO
IPC: A61P3/04
Filed: 2004-08-26
Abstract: The present invention discloses compounds of formula (I); wherein Ar, Y, m, n, R1 and R4 are herein defined, said compounds being novel antagonists for melanin-concentrating hormone (MCH), as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such MCH antagonists as well as methods of using them to treat obesity, metabolic disorders, eating disorders such as hyperphagia, and diabetes.