baber/WOPTO huggingface dataset:
Patent EP-4268820-A3 (EP)
Title: Combination therapy of c-c chemokine receptor-9 (ccr9) inhibitors and anti-alpha4beta7 integrin blocking antibodies for the treatment of inflammatory bowel disease
Inventor: EBSWORTH KAREN
IPC: C07K16/28
Filed: 2015-10-05
Abstract: Provided herein are compositions, methods and kits for treating inflammatory bowel disease (IBD) such as Crohn's disease and ulcerative colitis in a mammal in need thereof. The method include administering to a subject with IBD a combination therapy containing a therapeutically effective amount of a chemokine receptor 9 (CCR9) inhibitor compound and a therapeutically effective amount of an anti-a4p7 integrin antibody such as vedolizumab. Also provided herein is a kit containing the CCR9 inhibitor compound and anti-a4p7 integrin antibody.
Patent EP-0028868-A3 (EP)
Title: Bloc de construction en béton
IPC: E04B1/84
Filed: 1980-11-10
Abstract: Bloc de construction en béton dont au moins une face 4 
présente de propriétés d'absorbant acoustique, ce bloc 
étant massif dans sa zone 5 voisine de ladite face et 
délimitée par cette dernière, au moins une partie 
importante des matériaux constituant cette zone 5 étant 
à structure alvéolaire dont les alvéoles s'ouvrent 
sur ladite face 4.
Patent EP-0033214-A3 (EP)
IPC: A61K31/41
Filed: 1981-01-21
Abstract: Process for the preparation of compounds of the formula 
  
and pharmaceutically acceptable salts thereof wherein R₁, R₂, 
R₃ and R₄ which may be the same or different, represent 
hydrogen, halogen, nitro, lower alkyl or lower alkoxy, where 
lower means of up to six carbon atoms, or any adjacent two of 
R₁ to R₄ taken together represent an alkylene group containing 
from 3 to 5 carbon atoms or a 1,4-buta-1,3- dienylene group, 
by removal of CH₂R₅ wherein R₅ is phenyl optionally substi­
tuted with one or two groups selected from C₁₋₄ alkyl, C₁₋₄ 
alkoxy, halogen or nitro from a compound of formula (II): 
  
with an alkali metal C₁₋₄ primary alkoxide.
Patent EP-0065193-A3 (EP)
Title: Process for the manufacture of powdery, finely divided preparations of carotenoids or retinoids
IPC: A23L5/41
Filed: 1982-05-05
Abstract: Finely divided, pulverulent carotinoid or retinoid compositions, in which the carotinoid or retinoid essentially has a particle size of less than 0.5 micron, are prepared by a process wherein a carotinoid or retinoid is dissolved in a volatile, water-miscible, organic solvent at from 50 DEG  C. to 200 DEG  C., if necessary under superatmospheric pressure, within the space of less than 10 seconds. The carotinoid is immediately precipitated, in a colloidally disperse form, from the molecularly disperse solution by rapidly mixing the latter with an aqueous solution of a swellable colloid at from 0 DEG C. to 50 DEG  C., and the resulting dispersion is freed from the solvent and the dispersing medium in a conventional manner.
Patent EP-0073357-A3 (EP)
IPC: B23P19/04
Filed: 1982-08-04
Abstract: An assemblable and stackable crate of plastic material, 
particularly of injection-molded plastic material, for the 
packaging of agricultural products, consists of a bottom (F) 
and of sidewalls (P1, P2) which in a second operative step 
are secured in their erected position of use to the bottom (F). 
Between each one of the sidewalls (P1, P2) and the bottom 
(F) there are provided articulated connection means (1, 3, 
4; 5, 6; L) which permit to raise the sidewalls (P1, P2), 
initially coplanar to the crate bottom (F), in order to form the 
crate by an angular movement through about 90°. Fastening 
joints are also provided between each one of the sidewalls 
(P1, P2) and the bottom (F), as well as between two adjacent 
sidewalls (P1 and P2), each fastening joint consisting of at 
least two cooperating connection elements (7, 8; 9, 10; 12; 
11, 13) which are interengageable following the relative 
raising of the crate sidewall or sidewalls with respect to the 
bottom, and which are adapted for preventing the separa­
tion of the crate sidewalls from the bottom perpendicularly 
thereto, and also the separation of the sidewalls from each 
other.
Patent EP-0071400-A3 (EP)
IPC: G05D3/12
Filed: 1982-07-21
Abstract: An improved spindle drive train for rotatably driving the 
spindle of a machine tool comprises a frame fastened to 
which is a motor whose shaft extends into the frame. Keyed 
on that portion of the motor shaft extending into the frame is 
a pinion gear which is in meshing engagement with one of 
the gear members of a cluster gear journaled in the frame for 
rotation about and transverse movement along an axis 
parallel to the motor shaft. Journaled into the frame parallel 
to the cluster gear is the tool-carrying spindle which has a 
shaft extending coaxially therefrom within the frame. The 
spindle shaft carries a plurality of gear thereon, each 
dimensioned to meshingly engage a corresponding cluster 
gear member, and each is aligned with one another so that 
when the spindle is at a predetermined angular orientation, 
the teeth on each of the gears line up permitting axial shifting 
of the cluster gear. The gears on the spindle shaft are spaced 
apart such that as the cluster gear is biased along its axis, 
one of the gears on the spindle shaft and its complementary 
cluster gear member engage just as another gear and its 
complementary cluster gear member disengage, assuring 
constant synchronism between the spindle and the motor. 
Motor shaft position is obtained by a resolver fastened 
directly to the motor shaft, thereby preventing excessive 
resolver back lash.
Patent EP-0097760-A3 (EP)
IPC: A23C21/02
Filed: 1983-02-21
Abstract: A beverage comprising whey and milk enzymes used for 
producing hard cheeses in an amount sufficient to provide 
an acidity of about 3,5 pH for the beverage. Optional flavor 
additives, e.g., fruit syrup may also be incorporated. The 
process of producing these beverages is also disclosed.
Patent EP-0100012-A3 (EP)
IPC: G01S/
Filed: 1983-07-08
Abstract: Device for cancelling false spureous radar echoes with 
Doppler filtering method and temporal correlations. The 
device allows a frequency selectivity with a memory on a 
plurality of antenna rotations, which is capable to distin­
guish false echoes from useful echoes, operating on a 
selective attenuation in the space of the frequency and of the 
time.
Patent EP-0100210-A3 (EP)
IPC: F04B51/00
Filed: 1983-07-21
Abstract: The device is used to measure the COP of a mechanical 
vapor-compression system and includes a power transducer 
(31) to measure the power to the compressor motor (11), tem­
perature sensors (43, 48, 46, 45) to measure respectively tem­
peratures of the inlet (14) and outlet (13) of the compressor 
(12) and the inlet (17) and outlet (21) of a fluid expansion 
means (20), and a microprocessor (62) to store losses typical 
of the motor, to store the pressure versus enthalpy characteris­
tics of the system under test, to store the temperature versus 
entropy characteristics of the system and to receive output sig­
nals of the temperature sensors, the microprocessor being 
operable to continuously determine the COP for the system as 
the system is operating.
Patent EP-0099791-A3 (EP)
Title: Equipment for stone extraction, e.g. marble or granite, especially from quarries and for roughing and squaring it
IPC: E21D9/10
Filed: 1983-06-29
Abstract: The machine comprises an automobile vehicle provided with a pivoting boom to which is pivotably mounted a beam carrying a pivotally mounted swingle-bar to which is coupled a rotary plate for supporting a frame provided with guiding uprights for a sawing unit. Hydraulic cylinders and motors are provided for adjusting respective positions of the boom, beam, swingle-bar, rotary plate and motor means of the sawing unit. Means are provided to maintain the frame in a fixed position when working a sawing step.
Patent EP-0130423-A3 (EP)
IPC: H01H51/22
Filed: 1984-06-12
Abstract: A polarized electromagnet comprises a generally E-­
shaped yoke (1) including a pair of outer legs (2, 3) and an 
intermediate leg (6) therebetween, the three legs (2, 3, 6) 
being interconnected by a base portion (4), and a coil (5) 
wound about the intermediate leg (6). A generally U-shaped 
armature (7) comprises a permanent magnet (10) and two 
pole plates (8, 9) attached to both ends of the permanent 
magnet (10). The armature (7) is so positioned that each 
pole plate (8, 9) extends between the intermediate leg (6) 
and a respective one of the outer legs (2, 3) of the yoke (1). 
The armature (7) may be fitted into a generally U-shaped 
resin member (12) integrally molded with portions (13a, 13b) 
extending outwardly to opposite sides of the pole plates (8, 
9) and slidable engaged in guide slots (11a, 11b) provided 
in the outer yoke legs (2, 3). When used in an electromagnet­
ic relay, these projecting portions (13a, 13b) form actuating 
members engaging movable contacts of the relay.
Patent EP-0152516-A3 (EP)
Title: Mine
IPC: F42B23/16
Filed: 1984-07-20
Abstract: 1. A mine having : a casing (10) ; a detonating cap (12) which can be ejected from the casing (10) and contains an explosive charge (16) and an explosive charge igniting device taking the form of a delay-action cap with an ignition point mechanism (18) and an ignition triggering device (19) actuated thereby ; and a propellant charge (13) having a propellant charge ignition device (14) for the substantially vertical ejection of the detonating cap (12) and a sensor for detecting objects from whose detection the activation of the propellant charge ignition device (14) and the explosive charge ignition device (17) is derived, characterized in that the explosive charge ignition device (17) has an ignition point adjuster (19) for adjusting the ignition point in the ignition point mechanism (18), and the sensor is formed by a locating device (42) having at least one receiver (21) and a connected evaluating unit (22) so constructed that it determines from the signals received the ignition point for the propellant charge ignition device (14) and the explosive charge ignition device (17) and delivers corresponding control signals thereto.
Patent EP-0144932-A3 (EP)
Title: Method and apparatus for extruding thermoplastic material
IPC: B29C48/41
Filed: 1984-11-30
Abstract: A gear pump assisted screw conveyor extrusion system utilizing a cartridge heating device disposed axially within the screw and having the drives for the gear pump and the screw correlated in speed to create relatively little pressure in the thermoplastic material being extruded such that relatively little mechanical working thereof occurs. The thermoplastic material is melted in the screw conveyor primarily by heat transfer from the cartridge heater and the gear pump is utilized for conveying the melted material under pressure to a subsequent work station. A relatively deep material-conveying spiral channel is provided in the screw for maximized extrusion output per revolution of the screw and minimized mechanical energy generation by the screw. A motionless mixer may be employed intermediate the screw and the work station to homogenize the melted material for reducing temperature gradients therein. The system advantageously is capable of extruding material at a substantially greater rate and a lower material temperature and with substantially increased power economy than conventional systems utilizing a high pressure, externally heated screw conveyor portion.
Patent EP-0146907-A3 (EP)
IPC: C10L1/02
Filed: 1984-12-17
Abstract: Zur Erzielung einer einphasigen Mischung von Benzin 
und wasserhaltigem Alkohol wird ein Lösungsvermittler 
vorgeschlagen, der etwa 5 - 40 Vol.% eines Stoffes aus der 
Gruppe der C₄- und C₅-Methyl-Ketone,  
20 - 60 Vol.% eines Stoffes aus der Gruppe der C₃- bis 
C₅-, bevorzugt C₄-Alkohole und  
20 - 40 Vol.% eines Glykols  
sowie gegebenenfalls zusätzlich etwa 2 - 8 Vol.% eines 
nichtionogenen Emulgators sowie gegebenenfalls weiter 
zusätzlich ein nichtselbstemulgierendes Glyzerin­
monodioleat enthält.
Patent EP-0123477-A3 (EP)
IPC: G06F3/033
Filed: 1984-04-11
Abstract: A digitiser table is provided under the surface of which 
are located a set of parallel X-conductors (1-6) and a set of 
parallel Y-conductors (14-19) arranged as a grid. They may be 
energised by electric currents to produce patterns of magnetic 
field close to the surface of the table, Means (92, 93; 94, 95) 
enables currents of constant polarity but of varying amplitude 
to be applied to successive pairs of conductors. A pen or 
cursor (22) having sensor means (33) therein responds to the 
local component of magnetic field perpendicular to the sur­
face of the table. The location of the sensor (33) between a pen 
of current carrying conductors is given by the ratio of the 
amplitudes of the currents applied to the two conductors of 
the pair when the resultant magnetic field component per­
pendicular to the surface of the table passes through a null 
value.
Patent EP-0136042-A3 (EP)
Title: Improvements in and/or relating to the carriage of comestibles and in particular to containers and related means and methods suitable for such purposes
IPC: B65D88/74
Filed: 1984-08-17
Abstract: A method and means for transporting a quantity of comestibles (preferably at lowered temperatures) where at least continual monitoring of at least the oxygen level of the atmosphere to which the comestible is subjected is carried out. Preferably the carbon dioxide level is also monitored. Automatic adjustment of the oxygen content and carbon dioxide content in response to the monitoring is carried out using a positive infusion of ambient air and the scrubbing of the gas atmosphere to which the comestibles are subjected respectively. Ideally the comestibles are of a respiring nature such as would be the case with plants (whether cut or uncut), fruit and vegetables and they are carried in a container suitable for shipping where a seal of the container sufficient to ensure that less oxygen from the ambient air can diffuse into the container than is required for respiration by said quantity and sufficient to ensure a product of carbon dioxide by said quantity as a result of respiration than can diffuse from the container.
Patent EP-0136871-A3 (EP)
Title: Fiber optic amplifier
IPC: H01S3/23
Filed: 1984-09-20
Abstract: @ A pair of small diameter optical fibers (12, 14) are arranged in a side-by-side configuration, the first fiber (12) providing a passive guide for pump light, and the second fiber (14) formed of a material, such as Nd:YAG which has amplifying properties at the signal frequency. The signal to be amplified propagates through the second fiber (14) resulting in amplification of the signal. The first fiber (12) is pumped from one or both ends, utilizing a cone shaped rod (50) which is optically coupled thereto. A plurality of pump light sources (60) are mounted on the end face (58) of the rod (50) to introduce collimated pump light into the large end (52) of the cone shaped rod (50). Total internal reflections on the cone walls compress the pump light to a small, fiber-size diameter end (54) for propagation through the pump fiber (12) and absorption by the active fiber (14). The pump light sources (60) are offset from the axis (72) of the rod (50) to excite high order modes in the pump fiber (12) to enhance absorption by the active fiber (14). The pump light sources (60) preferably comprise high power laser diodes (64) and collimating microlenses (62). By utilizing the cone-shaped rod (50) to couple light from the high power laser diodes (64) to the pump fiber (12), high pump power densities can be achieved, yielding increased amplification.
Patent EP-0142990-A3 (EP)
Title: Inspecting articles
IPC: G01N21/88
Filed: 1984-11-16
Abstract: The condition of an article e.g. a multihead tool array is 
compared after having been subjected to some operation 
with its previous condition e.g. before and after a drilling or 
other operation of the tool array by forming an image, e.g. a 
video image, of the article before the operation and automa­
tically comparing it with a second such image formed after 
the operation. Known image enhancement techniques can 
be used, and statistical techniques used in data processing 
equipment to detect significant differences between the 
images.
Patent EP-0150670-A3 (EP)
IPC: B22D11/20
Filed: 1984-12-13
Abstract: Bei einem Verfahren zum Bestimmen und Regeln eines 
Niveaus einer Metallschmelze in einer Giessform, Füh­
rungsrinne od. dgl. wird die Grösse von mittels einer Mess­
spule in der Metallschmelze induzierten Wirbelströmen ge­
messen, welche ein Mass für den Abstand von Messspule 
zu Metallschmelze ist. Dabei werden die Wirbelströme auf 
der Metallschmelzeoberfläche dieser induziert, ihre Grösse 
mit einem Soll-Wert verglichen und nach deren Differenz 
die Zuflussmenge an Metallschmelze geregelt.  
     Eine hierzu bestimmte Vorrichtung sieht vor, dass die 
Messspule (20) über der Metallschmelze angeordnet und 
mit einer elektronischen Einheit (28) verbunden ist, welche 
die Messspule (20) mit dem für die Erzeugung der Wirbel­
ströme notwendigen Wechselstrom versorgt und die Grösse 
der Wirbelströme misst, und dass die elektronische Einheit 
(28) mit einer Regeleinrichtung (9) zum Vergleich der ge­
messenen Ist-Werte der Grösse der Wirbelströme mit ei­
nem Soll-Wert gekoppelt ist, welche eine Einheit (11) zum 
Bestimmen der Durchflussmenge an Metallschmelze durch 
ein Ausflussrohr (2) od. dgl. ansteuert).
Patent EP-0168660-A3 (EP)
IPC: G11B31/00
Filed: 1985-06-19
Abstract: A magnetic recording/reproducing apparatus of small 
size, small weight, and suitable for incorporation into a 
child's toy or the like. A magnetic disc is supported on a 
shaft, the latter being driven rotationally by a wind-up 
spring. A governor is provided for controlling the releasing 
force of the spring to thereby cause the disc to be rotated 
at a constant speed. A magnetic head is moved linearly and 
radially along the disc in synchronism with the rotation of 
the disc supporting shaft and in sliding contact with the disc. 
A spring-biased mode changeover member is provided for 
selecting between the recording and reproducing modes, 
the mode changeover member being normally urged to the 
reproducing mode position.
Patent EP-0175286-A3 (EP)
Title: In vitro cell culture system and method
IPC: C12N5/00
Filed: 1985-09-12
Abstract: In vitro cell culture systems for anchorage-dependent mammalian cells using solid substrates of mitogenic calcium compounds, such as hydroxyapatite and tricalcium phosphate forms of calcium phosphate and calcium carbonate. The calcium solid substrates can be in the form of granules with a particle size of at least 0.050 mm. or in the form of solid bodies and may be either porous or non-porous. Unique features of cells cultured in the stated in vitro cell culture systems include the growth of cells in layers many cells thick, growth of cells that maintain their phenotype and the ability to culture cells for extended periods of time.
Patent EP-0159177-A3 (EP)
Title: Disc separating and feeding apparatus for disc copying machine
IPC: G11B17/10
Filed: 1985-04-09
Abstract: automatic disc separating and feeding apparatus (2) for a disc copying machine (1). The apparatus includes a disc sucking and sliding device for sucking up uppermost one (4b) of stacked discs which compreises a stationary plate (7) and a sliding plate (8) each provided with through-holes (22,23) adapted to form together air vents varied in size depending upon the relative position of the plates (7,8). The vents communicate with a negative pressure chamber (12) enabling the uppermost disc (4b) to be sucked up. It is then transferred sideways to a feeding device (31) to a disc drive (30).
Patent EP-0178187-A3 (EP)
Title: Apparatus and method for continuously producing filled dough pieces
IPC: A21C11/10
Filed: 1985-10-14
Abstract: An apparatus and method for continuously producing filled dough pieces (19) is provided. A pair of toothed rotary disc cutters (2,2') are arranged on a conveyor belt (4) feeding a filled cylindrical dough body (18). A plurality of dividers (5) mounted on the periphery of a wheel (11) are disposed between and above the teeth. The dividers (5) and the teeth (1) rotate about their own axes to flatten the cylindrical dough body and to split it by their cooperatively synchronized movement whereby completely incrusted spherical or variously shaped filled dough pieces (19) are produced.
Patent EP-0195300-A3 (EP)
IPC: C07C15/44
Filed: 1986-03-03
Abstract: Die vorliegende Erfindung betrifft neue Isoxazolidine, 
der Formel I 
  
in welcher  
n für 2 oder 3 steht,  
R¹ für H oder Alkyl steht,  
R² für gegebenenfalls substituiertes Alkyl, Cyclo­
alkyl, Alkenyl, Alkinyl, Aryl sowie für gesättigte 
oder ungesättigte heterocyclische Reste die gege­
benenfalls substituiet sind, steht,  
 
 
A für zwei oder dreiwertige Aryl- oder Heteroaryl­
reste steht, die gegebenenfalls durch Substituenten 
aus der Reihe Alkyl, Aryl, Aralkyl, Alkoxy, Alkyl­
thio, Halogen, CN, OH, Halogenalkyl, Halogenalkoxy, 
Halogenalkylthio, Alkoxyalkyl, gegebenenfalls halo­
gensubstituiertes Methylendioxy oder Ethylendioxy 
substituiert sind.  
     Die neuen Isoxazolidine der Formel I können in Form 
ihrer Enantiomere, Diastereomere sowie als Salze mit 
anorganischen oder organischen Säuren vorliegen.  
     Sie eignen sich als Schädlingsbekämpfungsmittel.
Patent EP-0200926-A3 (EP)
IPC: A61F2/24
Filed: 1986-04-03
Abstract: A prosthetic heart valve comprises a suture ring sup­
porting a stent which surrounds a conduit bearing a plurality 
of flexible valve leaflets. The conduit extends beyond the 
end of the suture ring.
Patent EP-0206066-A3 (EP)
Title: Ciculating fluid-bed combustion device
IPC: B01J8/00
Filed: 1986-06-07
Abstract: In a combustion device with a circulating fluid-bed formed from a fluidised-bed reactor (10), solids separator (20) and return line (28), which in addition to the fluidisation gas supply (16) has at least one supply for oxygen-containing secondary gas (17), and also with at least one fluidised-bed cooler (34) which is equipped with cooling elements (60) and is connected via a line (32) to the solids separator (20) or to the return line (28), as well as with a solids return from the fluidised-bed cooler (34) into the fluidised-bed reactor (10), the fluidised-bed cooler (34) is arranged above the fluidisation gas supply (16) of the fluidised-bed reactor. The fluidised-bed cooler has a common wall (40) with the fluidised-bed reactor (10), which has a passage opening (56) for cooled solids into the fluidised-bed reactor (10). Preferably, the fluidised-bed cooler (34) is arranged between fluidisation gas supply (16) and secondary gas supply (17) of the fluidised-bed reactor (10), and the common wall (40) is cooled. Finally, the fluidised-bed cooler (34) can consist of a number of units equipped with cooling surfaces (60), which respectively have a common wall (40) with the fluidised-bed reactor (10) and a separate solids supply line (32). <IMAGE>
Patent EP-0216170-A3 (EP)
IPC: G06F12/08
Filed: 1986-08-26
Abstract: A system and method for managing a plurality of mass 
storage volumes associated with a multiprocessor computer 
system. Control is allocated to nodes (200, 210, 220, 230) 
which communicate through a commonly accessible mass 
storage device (100). A plurality of worker nodes (200,210,220) 
recognize needs for performance of certain storage mana­
gment functions and communicate those needs to a storage 
node (230) through transmission of signals to the commonly 
accessible storage medium. The storage node then retrieves 
these signals from the commonly accessible storage medium 
and performs the needed functions. Notification of comple­
tion may be communicated to the recognizing worker node by 
transmission of signals from the storage node to the com­
monly accessible storage medium. Recognizing worker 
nodes then retrieve these notification signals to complete the 
communication path.