baber/WOPTO huggingface dataset:
Patent ES-2285774-T3 (ES)
Inventor: FREIRE ERNESTO
IPC: G16B15/30
Filed: 1998-06-02
Granted: 2007-11-16
Abstract: A computer-based method for the identification of binding targets in proteins and other macromolecules. More particularly, the invention includes an algorithm aimed at predicting binding targets in proteins. This algorithm, named Woolford, requires knowledge of the high resolution structure of the protein but no knowledge of the location or identity of natural binding sites or ligands. Binding targets in the protein are identified and classified according to their expected optimal affinities. Binding targets can be located at the protein surface or at internal surfaces that become exposed as a result of partial unfolding, conformational changes, subunit dissociation, or other events. The entire protein is mapped according to the binding potential of its constituent atoms. Once binding targets are identified, optimal ligands are designed and progressively built by the addition of individual atoms that complement structurally and energetically the selected target. This algorithm is expected to have significant applications in structure-based drug design since it allows: 1) identification of binding targets in proteins; 2) identification of additional targets if the primary target is known; 3) design of ligand molecules with optimal binding affinities for the selected target; and 4) refinement of lead compounds by defining the location and nature of chemical groups for optimal binding affinity.
Patent ES-2170501-T3 (ES)
Title: Composicion farmaceutica antivirica que comprende acido glicirrizico y al menos una proteina que posee actividad antivirica.
Inventor: POMPEI RAFFAELLO
IPC: A61K38/47
Filed: 1998-05-06
Granted: 2002-08-01
Abstract: Una composición farmacéutica que comprende ácido glicirrícico y al menos una proteína que presenta una actividad antiviral.
Patent ES-2198743-T3 (ES)
Title: Proceso para la produccion de carbonatos aromaticos.
Inventor: TOJO MASAHIRO
IPC: C07C68/06
Filed: 1998-09-16
Granted: 2004-02-01
Abstract: Se refiere a un proceso para la producción de carbonatos aromáticos, el cual comprende la tran-sesterificación, en presencia de un catalizador que contiene un metal, un material de inicio seleccionado del grupo que consiste en un dialquil-carbonato, un alquil aril carbonato y una mezcla de los mismos, con un reactivo seleccionado del grupo que consiste en un compuesto monohidroxi-aromático, un alquil-aril-carbonato y una mezcla de los mismos.
Patent ES-2257818-T3 (ES)
Title: Polipeptidos de la malaria.
Inventor: WAHLGREN MATS
IPC: C12P19/26
Filed: 1998-09-18
Granted: 2006-08-01
Abstract: Un polipéptido aislado que se origina a partir de una proteína de membrana de eritrocitos infectados por malaria, que comprende 400-500 aminoácidos de la parte amino terminal de la secuencia según SEQ ID NO: 1.
Patent ES-2226220-T3 (ES)
Title: Maquina procesadora que incluye una estructura de reduccion de ruido.
Inventor: MATSUOKA MITSUO
IPC: B21D24/02
Filed: 1999-03-23
Granted: 2005-03-16
Abstract: Máquina procesadora que incluye una estructura de reducción de ruido que comprende: una estructura fija (2, 41, 50); una estructura amovible (6, 42) verticalmente amovible con respecto a dicha estructura fija (2, 41, 50); un miembro portador (4) para soportar una pieza de trabajo (W), estando dicho miembro portador (4) dispuesto verticalmente entre dicha estructura fija (2, 41, 50) y dicha estructura amovible (6, 42) y siendo verticalmente amovible con respecto a dicha estructura fija (2, 41, 50); un dispositivo amortiguador (43, 44, 3) para presionar verticalmente dicho miembro portador (4) en dirección hacia dicha estructura amovible (6, 42), incluyendo dicho dispositivo amortiguador (43, 44, 3) una almohadilla amortiguadora (44) que soporta dicho miembro portador (4); una palanca de arranque (11) unida mediante pivote a dicha estructura fija (2, 41, 50), siendo dicha palanca de arranque (11) conectable a dicha porción (51) de dicha almohadilla amortiguadora (44); y una leva operativa (20¿) fijada a dicha estructura amovible (6, 42) de forma que pueda conectarse con dicha palanca de arranque (11) tras el desplazamiento de dicha estructura amovible (6, 42), haciendo pivotar de esta forma dicha palanca de arranque (11) hasta su conexión con dicha porción (51) de dicha almohadilla amortiguadora (44) y accionando la misma, permitiendo de este modo que dicho miembro portador (4) se desplace hacia arriba antes de que dicha estructura amovible (6, 42) choque contra dicho miembro portador (4) y/o contra la pieza de trabajo (W) situada en dicho miembro portador (4).
Patent ES-2209279-T3 (ES)
Inventor: LANZA FABRIZIO
IPC: B65B31/04
Filed: 1999-05-21
Granted: 2004-06-16
Abstract: A hand-held suction pump for creating a vacuum in a container (2) provided with a suction valve (3), comprising an elongated outer casing in which an electric motor (7) and a piston pump (14, 15) driven by the motor (7) are accomodated, wherein the pump chamber (14) of the piston pump is connected by an inlet valve and a suction duct (28) to a hollow tip (34) at the free end of the casing for direct coupling with the suction valve of the container, the pump chamber being further connected by an outlet valve to an exhaust duct (29) having a duct opening on the outer surface of the wall of the outer casing for porting an exhaust flow to the exterior of the outer casing. In order to reduce noise caused by the exhaust flow, the duct opening of the exhaust duct (29) is overlapped by a baffle (38) which is separated by a gapped distance from the outer surface of the wall of the outer casing so as to deflect the exhaust flow exiting the duct opening by a substantial angle. <IMAGE>
Patent ES-2213953-T3 (ES)
Inventor: ELLER MARTIN
IPC: F23Q7/00
Filed: 1999-08-02
Granted: 2004-09-01
Abstract: The glow plug has an integral tube (1) providing a glow plug body and a sleeve enclosing heating and regulating coils (4,5). The tube has a glow plug body section (16) with a reduced diameter enclosing a glow element heating coil (4), a regulating section (16a) of slightly greater diameter, enclosing a regulating coil (5) and a connection section (16b) of greatest diameter enclosing a connection conductor (10).
Patent ES-2177197-T3 (ES)
Inventor: SPIJKER ENGBERT
IPC: F16D48/06
Filed: 1999-07-06
Granted: 2002-12-01
Abstract: A continuously variable transmission (1) is provided with: an endless transmission means (14) for transmitting a driving torque; a clamping force means (13-1, 13-2) coupled with the endless transmission means (14) for applying a clamping force there on; a control means (15) coupled with the clamping force means (13) for influencing the driving torque by controlling the clamping force applied on the endless transmission means (14); and a clutch (16) coupled with the control means (15), whereby the control means (15) is arranged to control the clutch such that said clutch (16) is allowed to slip continuously. The net effect of a practical implementation of the transmission in a vehicle is a fuel saving which, if a slip of around 5 rpm is permitted, amounts about 3-4%.  <IMAGE>
Patent ES-2204082-T3 (ES)
Inventor: LEFEVRE DIDIER
IPC: G01N1/31
Filed: 1999-07-19
Granted: 2004-04-16
Abstract: The device includes a stocking section (16) for new slides (18) placed in a pile, with an extractor unit (22) for extracting a slide from the pile, and a depositing post (34) for depositing a drop of blood (38) on a slide. There is a spreading post (48) for spreading a drop of blood and producing a blood smear (50). There is a marking post (79) having a marking head for marking an identification on the reserved zone (46) of the slide. There is also a drying post (80) for drying the smear, with a coloring post (90) for staining the smear. There is also an exit post (92) for evacuating the slide, and transfer unit for displacing the slide between the posts.
Patent ES-2230818-T3 (ES)
Title: Acoplamiento de tubo para conectar un vastago rigido tubular a un tubo de cateter flexible.
Inventor: NADAL GUY
IPC: A61M37/00
Filed: 1999-07-20
Granted: 2005-05-01
Abstract: La invención está relacionada con un dispositivo de acoplamiento tubular para conectar una barra rígida tubular (20) a un tubo de catéter flexible (40), el cual está adaptado para ser configurado alrededor de la mencionada barra rígida tubular. El dispositivo de acoplamiento tubular tiene un lumen interno que se ensancha axialmente hacia el extremo libre proximal del dispositivo de acoplamiento tubular, de forma que el extremo libre proximal (42) del tubo del catéter flexible se expanda radialmente en el ensanchamiento, cuando se configura alrededor de la barra rígida tubular. El ensanchamiento está situado entre el extremo libre proximal del dispositivo de acoplamiento tubular y la brida anular interna (16) extendiéndose desde la pared del dispositivo de acoplamiento tubular. La brida está ranurada, de forma que la mencionada brida esté dividida en sectores diferentes.
Patent ES-2194431-T3 (ES)
Title: Dispositivo de escape de gases para un motor de combistion interna.
Inventor: KRUGER KLAUS GERHARD
IPC: F01N3/28
Filed: 1999-01-06
Granted: 2003-11-16
Abstract: EL DISPOSITIVO DE GAS DE ESCAPE (11) POSEE UN CATALIZADOR (13) Y CONDUCCIONES (15) DE DOBLE PARED PARA LA UNION DE LA SALIDA DE GAS DE ESCAPE DEL MOTOR DE COMBUSTION INTERNA CON EL CATALIZADOR (13). EL DISPOSITIVO (11) MUESTRA DOS ENVUELTAS (31.32) DE UNA SOLA PIEZA, A PARTIR DE LAS CUALES SE FORMAN APROXIMADAMENTE CADA UNA DE LAS MITADES DE LA PARED DE CARCASA (27) DEL CATALIZADOR (13) Y LAS MITADES DE LAS PAREDES (19) EXTERIORES DE LAS CONDUCCIONES (15) DE AFLUENCIA DIFERENTES. CADA ENVUELTA (31,32) SE CONFIGURA A PARTIR DE UNA PORCION ORIGINALMENTE PLANA MEDIANTE CONFORMACION PLASTICA. DESPUES SE SUELDAN UNA CON OTRA LAS ENVUELTAS (31,32). ESTO PERMITE QUE LAS CONDUCCIONES (15) Y LA CARCASA (25) SE ELABOREN A PARTIR DE POCAS PARTES DE MANERA RAPIDA ASI COMO ECONOMICA Y QUE A TRAVES DE LAS TENSIONES ORIGINADAS POR MODIFICACION DE TEMPERATURA EN LAS ENVUELTAS (31,32) SE MANTENGA REDUCIDA LA CESION TERMICA AL MEDIO AMBIENTE EN LOS GASES DE ESCAPE CALIENTES, QUE CIRCULAN EN OPERACION A LOS MEDIOS (35) DE CATALIZADOR.
Patent ES-2230831-T3 (ES)
Title: Metodo y sistema para medir el rendimiento durante una actividad de ejercicio fisico.
Inventor: DAMEN ERIK P N
IPC: G01P7/00
Filed: 1999-02-04
Granted: 2005-05-01
Abstract: Un sistema para la medida de la velocidad de una persona mientras corre o camina a lo largo de una superficie. Un sensor de aceleración único (8) mide la aceleración en dirección frontal y proporciona una señal de aceleración que se amplifica (10) y se muestrea a continuación mediante un convertidor analógico a digital (12). La señal digital se procesa en un microprocesador (14) que ejecuta un algoritmo que determina la longitud de zancada y la duración de la zancada a partir de la señal de aceleración digitalizada y calcula la velocidad y la distancia recorrida. La información así obtenida se transmite por medio de un transmisor de frecuencia de radio (16) y se recibe en un receptor de frecuencia de radio (18) en un reloj u otro dispositivo (2) que comprende un monitor (20) que puede ser visto por el corredor o caminante. La velocidad y la distancia recorrida son sustituidas en el monitor (20), junto con otra información útil, tal como velocidad media, velocidad máxima, distancia total recorrida, calorías consumidas y pulso cardíaco.
Patent ES-2222688-T3 (ES)
Inventor: SEVERTSON STEVEN J
IPC: D21C5/02
Filed: 1999-03-03
Granted: 2005-02-01
Abstract: Methods for controlling wax and other contaminants by improving the dispersion of these materials through the addition of contaminant dispersants to the process of recycling paper and paperboard are disclosed. A preferred contaminant dispersant comprises: a) water; b) a plasticizer; c) an anionic dispersant; d) a surfactant wetting agent; and e) either 1) an acid or lecithin and optionally, a base, or 2) a preneutralized component.
Patent ES-2247790-T3 (ES)
Inventor: HIGUCHI M
IPC: G01N33/566
Filed: 1999-04-13
Granted: 2006-03-01
Abstract: The present invention provides a method for screening substances that promote oligomerization of receptor protein molecules or peptide fragments thereof, which comprises determining whether the receptor protein molecules or peptide fragments thereof are oligomerized when contacted with a test substance; a test kit for screening substances that promote the oligomerization of the receptor protein molecules or peptide fragments thereof, which comprises the receptor protein molecules or peptide fragments thereof and a buffer, and a substance identified by the above method, which promotes the oligomerization of the receptor protein molecules or peptide fragments thereof.
Patent ES-2196849-T3 (ES)
Title: 4-amino-2-aril-pirimidinas sustituidas, su preparacion, su utilizacion y preparados farmaceuticos que las contienen.
Inventor: SCHINDLER URSULA
IPC: A61P11/00
Filed: 1999-08-04
Granted: 2003-12-16
Abstract: La presente invención se refiere a compuestos de la fórmula I en la que R1, R2, R3 y R4 tienen los significados que se indican más adelante, y que son valiosas sustancias medicamentosas para el tratamiento y la prevención de enfermedades, por ejemplo, enfermedades cardiovasculares tales como hipertensión arterial, angina de pecho, insuficiencia cardiaca, trombosis o arterosclerosis. Los compuestos de la fórmula I tienen la capacidad de modular la producción propia del organismo de guanosín-monofosfato cíclico (cGMP) y, en general, son adecuados para el tratamiento y prevención de estados patológicos asociados con niveles alterados de cGMP. La invención se refiere, además a los procedimientos para la preparación de compuestos de la fórmula I, a su uso en el tratamiento y la prevención de los citados estados patológicos y para la fabricación de medicamentos contra los mismos, así como a preparados farmacéuticos que contienen compuestos de la fórmula I. cGMP es un importante mediador intracelular que, a través de la modulación de proteinquinasas, fosfodiesterasas y canales iónicos, dependientes de cGMP, desencadena una serie de efectos farmacológicos.
Patent ES-2234304-T3 (ES)
Inventor: IJDENS PIETER B
IPC: G06F3/06
Filed: 1999-09-23
Granted: 2005-06-16
Abstract: A storage file system is provided for data stored on a storage medium, and particularly for storage of data on optical disc storage medium. Each successive or alternate file of data included in the storage medium is represented by a respective allocation extent list with each allocation extent identifying locations of data segments for each file. Data in some data segments or portions of data segments may be shared by two or more files with each file having a respective allocation extent list entry referencing that segment and each such allocation extent maintaining byte-accurate pointers to the start and end of the data relevant to each file within the data segment. An allocation space table containing respective entries for each reference to a data segment or portion of a data segment, and optionally a free-space table identifying those data segments or portions of data segments available for rewriting, may be provided to allow for rapid reclamation of free within the storage medium.
Patent ES-2306527-T3 (ES)
Inventor: BEAUDOIN ADRIEN
IPC: A23K20/158
Filed: 1999-10-21
Granted: 2008-11-01
Abstract: Provided herein is a method for extracting lipid fractions from marine and aquatic animal material by acetone extraction. The resulting non-soluble and particulate fraction is preferably subjected to an additional solvent extraction with an alcohol, preferably ethanol, isopropanol or t-butanol or an ester of acetic acid, preferably ethyl acetate to achieve extraction of the remaining soluble lipid fraction from the marine and aquatic animal material. The remaining non-soluble particulate contents is also recovered since it is enriched in proteins and contains a useful amount of active enzymes. Also provided herein is a krill extract.
Patent ES-2292259-T3 (ES)
Title: Procedimiento para la produccion o mejora de la respuesta de linfocitos t frente a una celula diana mediante un complejo que comprende una molecula hla de clase i y unos medios de adhesion.
Inventor: SAVAGE PHILIP MICHAEL
IPC: C07K14/705
Filed: 1999-06-04
Granted: 2008-03-01
Abstract: Complejo que comprende una molécula HLA de clase I o un fragmento de la misma, comprendiendo la molécula HLA de clase I o fragmento de la misma: (i) una porción de unión de linfocitos T; y (ii) unos medios de adhesión para adherir selectivamente la molécula HLA de clase I o un fragmento de la misma a una célula diana; en el que la molécula HLA de clase I o un fragmento de la misma se une o se adhiere al péptido de reconocimiento, en el que el péptido de reconocimiento se prepara para ser presentado a dicha molécula HLA de clase I o su fragmento para el reconocimiento de los linfocitos T; en el que los medios de adhesión comprenden: (a) un polipéptido de enlace con una afinidad específica para una molécula sobre la superficie de la célula diana (b) un sistema de acoplamiento para el acoplamiento del polipéptido de enlace a la molécula HLA de clase I o un fragmento de la misma, en el que el sistema de acoplamiento comprende: una primera pequeña molécula unida al polipéptido de enlace, y una segunda pequeña molécula unida a la molécula HLA de clase I, en el que la interacción de las pequeñas moléculas forma un puente estable entre el polipéptido de enlace y la molécula HLA de clase I.
Patent PL-1685563-T3 (PL)
Title: Apparatus and method of playing back a storage medium storing text-based subtitle data including style information
Inventor: KANG MAN-SEOK
IPC: G11B27/10
Filed: 2004-11-09
Abstract: A storage medium includes text-based subtitle data including style information for use with an apparatus and a method of playing back the storage medium. The storage medium includes moving image data, and subtitle data for providing a subtitle for the moving image data. The subtitle data is recorded based on a text to be separated from the moving image data and includes information used to select or change an output style of the subtitle. Accordingly, the subtitle can be output using style information selected by a user, and a style in which a subtitle is output can be changed.
Patent PL-1559844-T3 (PL)
Title: Insulating element and composite thermal compound system
Inventor: Klose Gerd-Rüdiger
IPC: E04B1/76
Filed: 2005-01-26
Abstract: The thermal insulation panel (1), of mineral fibers (2) and a bonding agent and especially mineral and/or glass wool, has projecting ribs (10) on at least one main axis direction at the large surfaces (3,4), on the contact zones (5,6) between the insulation and the outer surfaces. The ribs are at equal intervals, with a semi-circular cross section. The core zone (9) is composed of compressed loops (11) of a primary nonwoven felt, with their deflections bonded together in at least one contact zone. The bonding agent is a mixture of phenol, formaldehyde and urea resins.
Patent PL-1640445-T3 (PL)
Title: Drum for an installation for aerobic fermentation of waste
Inventor: FELIDJ KARIM
IPC: B01F29/60
Filed: 2005-09-27
Abstract: A rotary drum for aerobic fermentation of waste, comprising ventilation ports with shutters to provide axial circulation of air, is new : A rotary drum for aerobic fermentation of waste, comprising ventilation ports with shutters to provide axial circulation of air. The fermentation drum, measuring up to 40 - 50 m long by 3 - 5 m in diameter and driven so that it rotates about a horizontal or slightly inclined axis (4), has a main cylindrical wall and an outlet with a door (13) in its transverse end wall (6), which also has one or more separate ventilation ports (20, 20a, 20b) with covers (23). The covers are in the form of shutters (28a, 28b) that are held in the closed position by springs (29) on rods (24) and are opened by a force applied against the effort of the springs. The ventilation ports and shutters make up a series of regularly-spaced assemblies (21a, 21b, 21c, 21d) in the drum end wall, and the shutters are opened in sequence by a curved bar (31) outside the drum as they reach the top point in its rotation.
Patent PL-1951436-T3 (PL)
Title: Coating device comprising flowing coating material for smooth or structured surfaces
Inventor: Döhring Dieter
IPC: B05D1/28
Filed: 2005-11-24
Abstract: The sheet (6) guided on a conveying device is first coated with a fluid material (8) guided through a receptacle (5) formed by a foil (3) and two pulleys (4,13) of different diameters. The plane or structured foil (3) is removed from a first drum (1), positioned on top of the coating (8) and the sheet (6) guided to a drying and hardening unit (7). The position of the plane or structured foil (3) is controlled with speed sensors in order to synchronize the motion of the sheet (6) and the foil (3). After passing the drying device (7) the foil is wound up on a second drum (2).
Patent PL-1705387-T3 (PL)
Title: Magazine strip
Inventor: KOLLMAR FRANK
IPC: F16B15/08
Filed: 2006-03-21
Abstract: The strip has a set of parallel intake bodies (5) that are arranged adjacent to each other, where each intake body comprises an inner opening. The inner opening takes up a shank of a fastening unit that is provided with a hub. The intake bodies are connected with each other by a connecting unit (10) that comprises a tear off point (12). An attenuation notch (18) runs in an axial direction of the inner opening.
Patent PL-1733782-T3 (PL)
Title: A method for removing carbon dioxide from sulphur dioxide containing flue gases
Inventor: ANTTILA MIKKO
IPC: B01D53/14
Filed: 2006-06-15
Abstract: A method and an apparatus for removing carbon dioxide (CO 2 ) from sulphur dioxide containing (SO 2 ) flue gases, wherein the flue gases are washed with washing solution in a scrubber (1), which comprises at least two washing stages (1a, 1b). In the first washing stage (1a) the flue gases are washed for removing the sulphur dioxide in the flue gases and after that in the second washing stage (1b) for removing carbon dioxide (CO 2 ). Sodium carbonate solution (Na 2 CO 3 ) is used as washing solution in both the first (1a) and the second washing stages (1b).
Patent PL-1863866-T3 (PL)
Title: Method for producing polymer powders
Inventor: WEISS AXEL
IPC: C08J3/12
Filed: 2006-03-20
Abstract: The present invention relates to the production of a polymer powder with improved powder properties, and to its use as impact modifier for rigid polyvinyl chloride (PVC) applications. The impact modifier is composed of emulsion polymer particles which have a core-shell structure, where the shell is composed of a hard polymer and the core is composed of a soft, crosslinked rubber polymer.
Patent PL-1990566-T3 (PL)
Title: Venting and aerating valve for pipes and fittings
Inventor: GÖTZINGER STEFAN
IPC: F16K24/04
Filed: 2007-05-08
Abstract: A cup-shaped valve body (6) becomes smaller in cross-section towards the bottom for closing and opening a valve outlet (3). A seal cup cooperates with a float (11) on the valve. A cup seal (8) is placed between the valve body and seal cup, and is movable into different closing or opening positions lying across the passage orifices (10) of the valve body. The seal cup has an internal contour that becomes wider towards the top to conform to the external contour of the valve body.