baber/WOPTO huggingface dataset:
Patent NZ-503432-A (NZ)
Title: Azabenzimidazole-based compounds for modulating serine/threonine protein kinase function
Inventor: MCMAHON GERALD
IPC: C07D/
Filed: 1998-09-23
Abstract: The use of an azabenzimidazole-based compound of formulae I, II, or III in the manufacture of a medicament for modulating the function of serine/threonine protein kinase, wherein: (a) R1, R2, R3, and R4 (i) hydrogen; (ii) saturated or unsaturated alkyl; (iii) NX2X3, where X2 and X3 are hydrogen, saturated or unsaturated alkyl, or homocyclic or heterocyclic ring moieties; (iv) halogen or trihalomethyl; (v) a ketone of formula -CO-X4, where X4 is hydrogen, alkyl, or homocyclic or heterocyclic ring moieties; (vi) a carboxylic acid of formula -(X5)n-COOH or ester of formula -(X6)n-COO-X7, where X5, X6, and X7 are alkyl, or homocyclic or heterocyclic ring moieties and where n is 0 or 1; (vii) an alcohol of formula (X8)n-OH or an alkoxy moiety of formula -(X8)n-O-X9, where X8 and X9 are hydrogen, saturated or unsaturated alkyl, or homocyclic or heterocyclic ring moieties, wherein said ring is optionally substituted with one or more of alkyl, alkoxy, halogen, trihalomethyl, carboxylate, nitro, and ester and where n is 0 or 1; (viii) an amide of formula -NHCOX10, where X10 is alkyl, hydroxyl, or homocyclic or heterocyclic ring moieties, wherein said ring is optionally substituted with one or more of alkyl, alkoxy, halogen, trihalomethyl, carboxylate, nitro, and ester; (ix) -SO2NX11X12, where X11 and X12 are hydrogen, alkyl, or homocyclic or heterocyclic ring moieties; (x) a homocyclic or heterocyclic ring moiety optionally substituted with one, two, or three of alkyl, alkoxy, halogen, trihalomethyl, carboxylate, nitro, and ester moieties; (xi) an aldehyde of formula -CO-H; and (xii) a sulphone of formula -SO2-X13, where X13 is saturated or unsaturated alkyl, or homocyclic or heterocyclic ring moieties; (b) Z1 and Z2 are nitrogen, sulfur, oxygen, NH and NR4, provided that if one of Z1 and Z2 is nitrogen, NH, or NR4 then the other of Z1 and Z2 is nitrogen, sulfur, oxygen, NH, or NR4; and (c) Z3 and X1 are nitrogen, sulfur, and oxygen.
Patent NZ-511387-A (NZ)
Title: System and method for frequency up-conversion
Inventor: SORRELLS DAVID F
IPC: H04B7/12
Filed: 1999-10-18
Abstract: A method of up-converting a signal comprises firstly of gating a first reference signal (3106) under the control of a first modulated information signal (3104) to generate a first gated reference signal (3114, 3502). An up-converted information signal (3506) is obtained by isolating at least one harmonic of the first gated reference signal.
Patent NZ-512726-A (NZ)
Title: Device for carrying out chemical reactions
Inventor: HEIMBERG WOLFGANG
IPC: B01J19/00
Filed: 1999-12-16
Abstract: A device for carrying out chemical reactions comprising a  reaction slider in which a plurality of through  openings are  configured as reaction chambers and a selection  slider which  is  arranged  on the upper surface  of  the  reaction slider  and  which  has  at  least  one  traversing  control opening.   The selection slider is displaceable relative  to the  reaction  slider  in  such a manner  that  the  control opening   thereof  is  aligned  with  one  of  the  reaction chambers  of  the  reaction  slider  so  that  a  traversing connection  for  supply  of  the  reaction  chamber  with  a predetermined  reagent  is formed.  The  device  is  further provided  with  a  slider  for  chemical  agents  which   is arranged  below the reaction slider and which is  configured with   through  openings  for  feeding  chemicals   to   the individual  reaction chambers of the reaction slider.   Also provided  is  a  means  for impinging  the  sliders  with  a predetermined   force   and   further   provides   a   valve arrangement with which chemicals can be fed to the  chemical slider as a premix.
Patent NZ-516109-A (NZ)
Title: Amphiphilic drug-oligomer conjugates with hydrolyzable lipophile components and methods for making and using the same
Inventor: EKWURIBE NNOCHIRI
IPC: A61K47/48
Filed: 2000-06-19
Abstract: Hydrolysable drug-oligomer conjugates, pharmaceutical compositions comprising such conjugates and methods for making and using such conjugates and pharmaceutical compositions. For example, a conjugate of insulin, PEG and oleic acid can be orally administered.
Patent NZ-520601-A (NZ)
Title: Locking mechanism for portable electric tool
Inventor: LAM CHIN HUNG
IPC: B25F5/02
Filed: 2002-08-07
Abstract: A locking mechanism for adjustably positioning opposing housing members of a portable electric tool which are pivotally connected to one another along a pivot axis (24).  The locking mechanism comprises: a first housing member (14) including a channel (114) formed adjacent a proximal end, the channel being spaced apart from the pivot axis; a second housing member (16) pivotally connected to the first housing member rotatably adjustable about the pivot axis between a first position and at least one second position, the first and second housing members cooperating along a common plane perpendicular to the pivot axis; a spring (104) disposed within the channel of the first housing member; a pin (106) biased against the spring shiftable in the passage between a locked position and an unlocked position; and a locking member (108).  The second housing member includes a plurality of apertures (118) formed through a proximal end alignable with the channel in the first housing member to form a passage (120) therebetween.  The locking member is disposed adjacent the plurality of apertures in the second housing member, and includes at least one projection (132) extending through one of the plurality of apertures to selectively position the pin in the passage relative to the common plane.  The locking member engages in an upper end of the pin to position the pin between the locked position wherein the pin extends through the common plane and cooperates with both the channel and aperture to lock the first housing member relative to the second housing member, and the unlocked position wherein the upper end of the pin is postioned below the common mating plane (22) allowing the first housing member to rotate relative to the second housing member about the pivot axis.
Patent NZ-520648-A (NZ)
Title: Bevel adjustment mechanism for a compound miter saw
Inventor: BRAZELL KENNETH M
IPC: B27B5/29
Filed: 2002-08-09
Abstract: A miter saw (10) including a base (12), a turntable (14) rotatably mounted to the base having a planar upper surface, a fence assembly (26) affixed to the base, a saw assembly (46) including an elongate arm (54) having a fixed end pivotally attached to the turntable, a distal end forming a handle (60) and a central region therebetween, a motor assembly disposed on the elongate arm, the motor assembly including a rotary spindle supporting a cutting disk (32) and a motor operatively connected to the rotary spindle, and a bevel adjustment mechanism (40) for adjusting the angle of inclination of the cutting disk relative to the turntable upper surface (28). The bevel adjustment mechanism includes a first knuckle (44) for adjusting the angle of inclination of the cutting disk about a tilt axis (48), the first knuckle including a fixed portion (80) mounted to the turntable adjacent to an outer periphery of the turntable, a locking flange (88) extending radially outward of the tilt axis, a rotatable portion (84) cooperating with the fixed portion having a first flange (94) with an arcuate channel (98) spaced radially outward of the tilt axis and a second flange (96) having a scale provided thereon, and a locking member (92) extending through the arcuate channel in the first flange and into a passage in the locking flange of the fixed portion. The second flange is on an opposite side of the tilt axis to the first flange, the scale on the second flange cooperates with an indicator on the fixed portion, and the first and second opposing flanges lie in a plane generally perpendicular to the tilt axis.
Patent NZ-520849-A (NZ)
Title: Barrel for an injector
Inventor: SIMMONDS WAYNE
IPC: A61D7/00
Filed: 2002-08-19
Abstract: A barrel for an injector including at a front end thereof an open bore adapted to receive therein a tip member, the length of the bore enabling at least a portion of the tip member to be accommodated therein so that an internal surface of the bore extends over and at least partially encases the said tip member, thereby, in use, strengthening a connection between the barrel and the tip member, wherein an internal surface of said bore is adapted to accommodate at least one sealing means to provide a substantially liquid tight seal between said tip member and said bore.
Patent NZ-521133-A (NZ)
Title: Human herpesvirus 6A and 6B transfer factors for the treatment of chronic fatigue syndrome and multiple sclerosis and methods to produce the transfer factors
Inventor: WILSON GREGORY B
IPC: A61K35/20
Filed: 2001-02-02
Abstract: A cell-free fluid of a mammary gland secretion of a human herpesvirus-6A ( HHV-6A ) or human herpesvirus-6B ( HHV-6B ) immunized lactating mammal is described. The fluid can be in the form of a lyophilized product and preferably the mammal is a bovine. The lyophilized product can be used in the manufacture of a medicament for treating chronic fatigue syndrome or multiple sclerosis.
Patent NZ-523052-A (NZ)
Title: Method for preparing cyclohexane carboxylic acids
Inventor: DIEDERICH ANN M
IPC: C07C225/00
Filed: 2002-12-09
Abstract: A method for preparing 4-substituted-4-cyanocyclohexane carboxylates by forming the cyclohexane ring by treating a a,a-bis(2-haloethyl)-4-benzeneacetonitrile with a dialkyl malonate and decarboxylating the resulting diester is disclosed.
Patent NZ-525209-A (NZ)
Title: Treatment of transgenic corn seeds with clothianidin
Inventor: ASRAR JAWED
IPC: A01N63/10
Filed: 2001-10-02
Abstract: A method for protecting a transgenic corn plant against feeding damages by one or more pests comprises providing a seed for the transgenic plant wherein the seed comprises a transgenic event having activity against at least one or more pests and treating the seed with an amount of clothianidin which in combination with the transgenic event is effective to protect a corn plant which grows from the corn seed against feeding damage by at least one of the one or more pests to a degree greater than would be expected due to either the clothianidin or the transgenic event alone. Preferably the transgenic event comprises the ability to express a Cry3 protein.
Patent NZ-532844-A (NZ)
Title: Use of a cannabinoid receptor agonist for the treatment of gastroesophageal reflux disease
Inventor: LEHMANN ANDERS
IPC: A61P11/04
Filed: 2002-11-20
Abstract: Disclosed is the use of cannabinoid receptor agonists for the manufacture of medicaments for the inhibition of transient lower esophageal sphincter relaxations (TLESRs), for the treatment of gastroesophageal reflux disease (GERD), reflux, regurgitation and managing failure to thrive.
Patent NZ-533932-A (NZ)
Title: MS11 gene product encoding for a phosphoglycerate kinase, and a purine nucleoside phosphatase and glucose-6-phosphate isomerase proteins from Group B streprococcus and their use in treating bacterial infection
Inventor: HUGHES MARTIN JOHN GLENTON
IPC: C07K16/40
Filed: 1999-12-22
Abstract: A peptide encoded by the nucleotide sequence of SEQ ID NO: 3, or a homologue having greater than 70% sequence similarity is described. The peptide sequence can be the amino acid sequence of SEQ ID NO: 4 and can be obtained from Group B streptococcus. The peptide or polynucleotide can be used in a medicament for the treatment of bacterial infections, preferably when the infection is a focal or urinary tract infection. Also described are antibodies and hosts transformed with the peptide.
Patent NZ-535027-A (NZ)
Title: Sheet pile
Inventor: MACDONALD CHRISTOPHER GERARD
IPC: E02D5/08
Filed: 2003-02-03
Abstract: An elongated element (1) having a cross-sectional shape permitting the element to be interlocked with adjacent elements, the element having a basic square shape with interlocking members (4,6,8) on at least three sides of the element, wherein the proportions of the element and the interlocking members are such that the elements can be interlocked in side by side and/or overlapping relationship.
Patent NZ-537304-A (NZ)
Title: Ring-substituted diphenyl azetidinones, method for the production thereof, medicaments containing said compounds, and use thereof
Inventor: JAEHNE GERHARD
IPC: A61K31/195
Filed: 2003-06-04
Abstract: Described is a compound of formula I, wherein R1, R2, R3, R4, R5, and R6, independently of one another, are chosen from:(C1-C30)-alkylene-(LAG)n, wherein at least one carbon atom of the alkylene radical is replaced by aryl or heteroaryl radicals, which may be substituted up to three times by R7, or by (C3-C10)-cycloalkyl or heterocycloalkyl radicals, which may be substituted up to four times by R7, and wherein at least one carbon atom of the alkylene radical may be replaced by -S(O)n-, where n=0-2, -O-, -(C-O)-, -(C=S)-, -CH=CH-, -Ca"C-, -N((C1-C6)-alkyl)-, -N(phenyl), -N((C1-C6)-alkyl-phenyl)-, -N(CO-(CH2)1-10-COOH)- and -NH-; or H, F, Cl, Br, I, CF3, NO2, N3, CN, COOH, COO(C1-C6)-alkyl, CONH2, CONH(C1-C6)-alkyl, CON[(C1-C6)-alkyl]2, (C1-C6)-alkyl, (C2-C6)-alkenyl, (C2C6)-alkynyl, or O-(C1-C6)-alkyl, where at least one hydrogen in the alkyl radical is replaced by fluorine; or SO2-NH2, SO2NH(C1-C6)-alkyl, SO2N[(C1-C6)-alkyl]2, S-(C1-C6)-alkyl, S-(CH2)n-phenyl, SO-(C1-C6)-alkyl, SO-(CH2)n-phenyl, SO2-(C1-C6)-alkyl, or SO2-(CH2)n-phenyl; wherein n=0-6, and the phenyl radical is may be substituted one or two times, each substituent chosen independently from: F, Cl, Br, OH, CF3, NO2, CN, OCF3, O-(C1-C6)-alkyl, (C1-C6)-alkyl, and NH2; or NH2, NH-(C1-C6)-alkyl, N((C1-C6)-alkyl)2, NH(C1-C7)-acyl, phenyl, or O-(CH2)n-phenyl, wherein n=0-6, and wherein the phenyl ring may be substituted up to three times, each substituent chosen independently from: F, Cl, Br, I, OH, CF3, NO2, CN, OCF3, O-(C1-C6)-alkyl, (C1-C6)-alkyl, NH2, NH(C1-C6)-alkyl, N((C1-C6)-alkyl)2, SO2-CH3, COOH, COO-(C1-C6)-alkyl, and CONH2. Also mentioned is the use of one or more of the compounds of formula I as a medicament which normalize lipid metabolism and for treating hyperlipidemia, arteriosclerotic manifestations, insulin resistances or lowering the serum cholesterol concentration.
Patent NZ-541452-A (NZ)
Title: Irrigation sprinkler lifter attachement for a vehicle
Inventor: PEARCE GEOFFREY MARK
Filed: 2005-07-26
Abstract: An irrigation sprinkler lifter includes a sprinkler engaging means configured to be connected to a vehicle, and to engage, lift from the ground and carry an irrigation sprinkler when the vehicle is driven. A sprinkler disengaging means is configured to be actuated by a driver of the vehicle to disengage the irrigation sprinkler from the sprinkler engaging means in order to place the irrigation sprinkler back on the ground. The irrigation sprinkler lifter includes an arm configured to attach at a first end to the vehicle and at its other end to the sprinkler engaging means, and to extend substantially horizontally from the vehicle so that the sprinkler engaging means is, in use, held by the arm at a distance from the vehicle and at a height above the ground that is not greater than the height of the irrigation sprinkler.
Patent NZ-542847-A (NZ)
Title: Feed supplement compositions
Inventor: BRUGGER ROLAND
IPC: A23K1/16
Filed: 2004-04-06
Abstract: Disclosed is a process for the preparation of thermostable, discrete, solid particles containing lactoferrin embedded in a protein- and/or starch-based carrier matrix by mixing the carrier matrix, lactoferrin and an optional internal lubricant in a horizontal screw extruder, mixing these components in the extruder under low shear and temperature, extruding and cutting said mixture into pieces and optionally drying said pieces as well as their use as food or animal feed supplements.
Patent NZ-546263-A (NZ)
Title: Penile prosthesis devices
Inventor: KUYAVA CHARLES C
IPC: A61F2/26
Filed: 2004-10-01
Abstract: Penile implant devices and methods are disclosed. A penile implant device in accordance with the present disclosure includes an implantable penile prosthesis pre-connected to a needle by a suture. The needle and suture may also be at least partially enclosed in a sheath or the like. In accordance with the present disclosure, a penile prosthesis is connected to a needle by a suture during a pre-operative storage period of the penile implant device. For example, the penile prosthesis may be connected to the needle during manufacture of the penile implant device.
Patent NZ-550009-A (NZ)
Title: Biodegradable intraocular implants of brimonidine tartrate, and methods for improving vision
Inventor: BURKE JAMES
IPC: A61K9/00
Filed: 2005-04-26
Abstract: Disclosed is a biodegradable intraocular implant comprising: brimonidine tartrate associated with a biodegradable polymer matrix that releases brimonidine tartrate at a rate effective to sustain release of an amount of brimonidine tartrate from the implant for a time effective to reduce ocular vascular occlusion in an eye in which the implant is placed, the time being at least about one week after the implant is placed in the eye, wherein brimonidine tartrate is provided in an amount of from 10 to 40% by weight of said implant. Also disclosed is the use of brimonidine tartrate associated with a biodegradable polymer matrix in the manufacture of a biodegradable implant for reducing ocular vascular occlusion in an eye of a patient wherein the implant is to be placed in an eye of the patient to provide a therapeutically effective amount of brimonidine tartrate to the patient for at least about one week, wherein brimonidine tartrate is provided in an amount of from 10 to 40% by weight of said implant.
Patent NZ-550587-A (NZ)
Title: Closure device with multiple colured closure elements
Inventor: BORCHARDT MICHAEL G
IPC: B65D33/25
Filed: 2005-04-13
Abstract: A bag closure device 221 comprises two fastening strips 249 250, with the first fastening strip 249 having first and second male closure elements 245 246 and the second fastening strip 250 having first and second female closure elements 247 248. On the first fastening strip 249 the first male closure element 245 has a first colour and the second male closure element 246 has a second colour. On the second fastening strip 250 the first female closure element 247 has a third colour and the second female closure element 248 has a fourth colour. On interlocking the two fastening strips 249 250, the first male closure element 245 with the first colour will interlock with the first female closure element 247 with the third colour producing a fifth colour. The second male fastening element 246 with the second colour will interlock with the second female fastening element 248 with the fourth colour producing a sixth colour.
Patent NZ-553206-A (NZ)
Title: Method for production of peptides/amino acids from animal and aquatic material using natural decomposing enzymes
Inventor: CARLSSON TOMAS
IPC: A23K1/16
Filed: 2003-07-29
Abstract: Disclosed is a method for producing a protein-free product comprising free amino acids and short peptides, wherein raw protein materials are crushed and hydrolysed with endogenous enzymes and passed through different separation processes, including coagulation of protein residues, in order to obtain the desired product. Further disclosed is a product obtained and uses thereof. According to a second aspect, a protein product enriched with free amino acids and short peptides is produced, wherein the raw protein materials are ground and hydrolysed with endogenous enzymes, and wherein the hydrolysate undergoes various separation processes. The product obtained comprises proteins, short and long peptides, free amino acids and minerals and has a low fat content and salt content. According to a third aspect, hydrolysation of a protein-containing raw material and separation of amino acids/peptides is carried out, wherein the hydrolysation is effected by using the endogenous enzymes of the protein-containing raw material. The hydrolysate is passed through a membrane filter, wherein peptide/amino acids follow a permeate stream, whilst the active enzymes continuously break down any protein residues that are deposited on the membrane surface. Furthermore, an amino acid and peptide product and an oil product are described and the use thereof is disclosed.
Patent NZ-553818-A (NZ)
Title: Methods and apparatus for managing group membership for group communications
Inventor: CORSON SCOTT M
IPC: H04B7/00
Filed: 2005-08-16
Abstract: A communications method for use in a group communications environment including an end node and an access node is disclosed. The method comprises transmitting from a wireless interface module having a connection to an element in the end node to the access node over a wireless communications link a group membership information change request signal requesting a change in group membership and operating a group communication module to monitor for receipt by the wireless interface module of a response determined by the access node to the group membership information change request signal. Also disclosed is the end node for use in a group communications environment comprising means for transmitting a group membership information change request signal requesting a change in group membership; means for receiving a response determined by an access node to a group membership information change request signal previously transmitted by the means for transmitting; and means for detecting a response to a group membership information change request signal which was previously transmitted by the means for transmitting. The end node is a member of zero, one, or more multicast groups at any point in time.
Patent NZ-575620-A (NZ)
Title: Preparation of substituted morphinan-6-ones and salts and intermediates thereof
Inventor: WANG PETER XIANQI
IPC: C07D217/20
Filed: 2007-09-06
Abstract: Disclosed is a process for the preparation of a ketal (1000), wherein the substituents are as defined in the specification, the process comprising converting a hexahydroisoquinoline (800) to a ketal (1000) in a series of steps, the series of steps comprising (a) converting hexahydroisoquinoline (800) to a N-formyl derivative (900) with a formylating agent and (b) converting the N-formyl derivative (900) to the ketal (1000) with a ketalizing agent in the presence of an acid catalyst, whereby the conversion of the hexahydroisoquinoline (800) to the ketal (1000) proceeds without an intermediate crystallization of the N-formyl derivative (900).
Patent NZ-576404-A (NZ)
Title: Compositions and methods for diagnosing and treating cancer involving dll4
Inventor: GURNEY AUSTIN
IPC: C12P21/08
Filed: 2007-09-28
Abstract: An isolated monoclonal antibody that specifically binds to N-terminal fragment of human DLL4 and affects growth of a tumor comprising cancer stem cells is described. Also described is a composition containing the antibody for the purposes of treating cancer.