Patent SG-11201804669Y-A (SG)
Title: (r)-carbidopa alone or in combination with a steroid for treating pain, inflammation, an inflammatory disease, an immune or autoimmune disease and tumour growth.
Inventor: PRITCHARD MARTYN
IPC: A61P35/00
Filed: 2016-12-07
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau 111111111M 11111111111111111111111111111111111111111111111111111111111111R111111111111111 (10) International Publication Number WO 2017/098237 Al WIPO I PCT (43) International Publication Date 15 June 2017 (15.06.2017) (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art 21(3)) before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) (51) International Patent Classification: A61P 35/00 (2006.01) A61P 19/02 (2006.01) A61K 31/198 (2006.01) A61K 31/573 (2006.01) A61P 29/00 (2006.01) (21) International Application Number: PCT/GB2016/053849 (22) International Filing Date: 7 December 2016 (07.12.2016) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 1521541.1 7 December 2015 (07.12.2015) GB (71) Applicant: PROXIMAGEN LIMITED [GB/GB]; Min- erva Building 250, Babraham Research Campus, Cam- bridge Cambridgeshire CB22 3AT (GB). (72) Inventors: PRITCHARD, Martyn; c/o Proximagen Lim- ited, Minerva Building 250, Babraham Research Campus, Cambridge Cambridgeshire CB22 3AT (GB). RICHARD- SON, Peter; c/o Proximagen Limited, Minerva Building 250, Babraham Research Campus, Cambridge Cambridge- shire CB22 3AT (GB). (74) Agents: GILL JENNINGS & EVERY LLP et al.; The Broadgate Tower, 20 Primrose Street, London EC2A 2ES (GB). W O 20 17 /098 237 Al (54) Title: (R)-CARBIDOPA ALONE OR IN COMBINATION WITH A STEROID FOR TREATING PAIN, INFLAMMATION, AN INFLAMMATORY DISEASE, AN IMMUNE OR AUTOIMMUNE DISEASE AND TUMOUR GROWTH. (57) : The present invention relates to (R)-carbidopa and pharmaceutical compositions thereof, and to a combined prepara- tion of (R)-carbidopa and a steroid, and to the use of the same in the treatment or prevention of medical conditions such as pain, in- flammatory diseases, immune or autoimmune disorders and tumour growth.