baber/WOPTO huggingface dataset:
Patent JP-4209678-B2 (JP)
IPC: A61K31/7105
Filed: 2002-01-09
Granted: 2009-01-14
Abstract: Method for inhibiting expression of a target gene (A) in a cell by introducing at least one oligoribonucleotide (O1) that has a double-stranded (ds) structure consisting of at most 49 sequential nucleotide (nt) pairs, with at least part of one strand (S1) complementary with (A), and has, at least one end, a single-stranded (ss) segment of 1-4 nt. Independent claims are also included for: (a) O1 that target any of 140 gene sequences defined in the specification; and (b) kit comprising at least one O1, at least one other oligoribonucleotide (O2) with same size and structure as O1 but not necessarily having an ss-end, and/or interferon. ACTIVITY : Cytostatic; virucide; protozoacide; antibacterial. No biological data given. MECHANISM OF ACTION : Antisense inhibition of gene expression. No biological data given.
Patent JP-4426184-B2 (JP)
IPC: C12Q1/6837
Filed: 2002-03-28
Granted: 2010-03-03
Abstract: The invention comprises a two-step process for analysis of polynucleotides by chain extension of multiple polynucleotide primers attached to solid supports by first performing PCR of the samples in the presence of multiple oligonucleotides in solution, the oligonucleotides of both sets being similar or identical. This produces immobilized single-strand polynucleotides containing genetic sequence data derived from sample molecules. In a second step, support-bound polynucleotides are interrogated by hybridization with a single labeled oligonucleotide probe or by second-strand synthesis with a primer-dependent polymerase using an oligonucleotide primer and nucleotide monomers, in which either or both of the primer and nucleotide monomers are labeled. Incorporation of label demonstrates the presence of two separate defined-sequence primers within the sample polynucleotide. The presence or absence within the sample of the multiple combinations of primers is demonstrable in a single experiment by use of suitable apparatus, such as an oligonucleotide array.
Patent JP-4282997-B2 (JP)
IPC: A61F2/82
Filed: 2003-01-07
Granted: 2009-06-24
Abstract: A system for bypassing an aneurysm comprises a first prosthesis and at least one second prosthesis communicating with the first prosthesis, and at least one third prosthesis communicating with the first prosthesis. The first prosthesis comprises a proximal end configured to engage a section of artery upstream of a junction between a first artery and a second artery. The second prosthesis is configured to bypass the aneurysm. The third prosthesis is configured to provide a fluid flow channel from the first artery into the second artery. <IMAGE>
Patent JP-4098113-B2 (JP)
IPC: B01D1/26
Filed: 2003-02-20
Granted: 2008-06-11
Abstract: Chromatographic separation process for producing at least two fractions involves at least partially evaporating the solvents of the produced fractions and separating the solvent vapors thus produced. The evaporation stage can be operated entirely using solvent vapors. Part of the solvent vapors separated from the other evaporated fraction is partially recycled. At least one of the fractions is preheated before evaporation.  Chromatographic separation process for producing at least two fractions involves at least partially evaporating the solvents of the produced fractions and separating the solvent vapors thus produced. Two fractions, extract and refined, are evaporated. The evaporation stage can be operated entirely using solvent vapors separated from one of the other evaporated fractions. Part of the solvent vapors separated from the other evaporated fraction is partially recycled, after evaporation of the considered fraction, to upstream of the evaporation stage of the other fraction. At least one of the fractions is preheated before evaporation with the solvent vapors separated from one of the evaporated fractions. The solvent is recycled. The chromatographic separation is type SMB or VARICOL.  An Independent claim is included for a chromatographic device comprising a central separation unit on a chromatographic bed; at least two fraction lines (1A, 1B); at least two evaporators (2A, 2B) connected to the fraction lines; heating fluid lines (3A, 3B) connected to the evaporators respectively; extraction lines (5A, 5B) downstream of the evaporators to receive the at least partially evaporated fractions as a liquid+vapor mixture, and separators (6A, 6B) connected to the extraction lines to receive the solvent in a line (7A, 7B). The two lines (1A, 1B) containing extract and refined respectively. An additional heat exchanger is fitted to the extract line and connected to the refined output line to supply the heating fluid. A solvent and heating fluid line (4B) leaves the evaporator and a line connected this line to the extract line feeding the evaporator for partial recycling. The evaporators are simple or multiple effect. The device also contains a solvent recycling device.
Patent JP-4324955-B2 (JP)
IPC: G01C19/5628
Filed: 2003-04-18
Granted: 2009-09-02
Abstract: <P>PROBLEM TO BE SOLVED: To prevent a peak-like temperature drift in a physical quantity measuring device for detecting detection vibration excited by an oscillator in response to a physical quantity applied on the oscillator.  <P>SOLUTION: This physical quantity measuring instrument is provided with the oscillator 1A, a support means for supporting the oscillator 1A in a plurality of portions, a driving means for exciting the oscillator 1A with driving vibration, and a detecting means for detecting the detection vibration excited by the oscillator in response to the physical quantity applied onto the oscillator. A spurious mode of vibration exists in the oscillator, and an absolute value of spurious detuning in the oscillator is ≥1000Hz.  <P>COPYRIGHT: (C)2005,JPO&NCIPI
Patent JP-3854261-B2 (JP)
IPC: B32B27/36
Filed: 2003-10-07
Granted: 2006-12-06
Abstract: The pipe (1) for transporting a fluid containing hydrogen is made from three polymer layers (2, 3, 4), the inner one being of a fluoridated thermoplastic. At least two of the layers are separated by an adhesive (5, 6).
Patent JP-4535728-B2 (JP)
IPC: A61P25/24
Filed: 2002-12-23
Granted: 2010-09-01
Abstract: The present invention relates to optionally substituted 1,3,8-triaza-spiro[4.5]decan-2-one compounds as monoamine receptor modulators; compositions comprising the same; methods of inhibiting an activity of a monoamine receptor with said compounds; methods of treating a disease condition associated with a monoamine receptor using said compounds; and methods for identifying a subject suitable for treatment using said compounds.
Patent JP-4447922-B2 (JP)
IPC: B21B41/08
Filed: 2003-01-28
Granted: 2010-04-07
Abstract: Disclosed are a method and a corresponding continuous casting machine ( 1 ) for continuously rolling a metal bar, particularly a steel bar, which is produced at a casting speed and the cross section of which is configured as a thin slab. Said metal bar is bent, dressed, and cut to length as required during cooling and is fed into a first roll stand for rolling once the temperature has been equalized. Optionally the metal bar can still be fed by modifying the casting machine by supporting ( 3 ) a vertically cast continuous slab ( 2 ) having a guide length that is adjusted to the casting rate. One or several segments of said continuous slab ( 2 ) is/are then dressed by bending and straightening, whereupon the continuous slab ( 2 ) is guided by a sling ( 11 ), which is supported from below, into a straightening driver ( 6 ) that is positioned at a distance approximately equivalent to the length of the sling before being cut to length ( 7 ).
Patent JP-4088254-B2 (JP)
IPC: C09K3/00
Filed: 2003-03-04
Granted: 2008-05-21
Abstract: UV absorber compositions are described, comprising (a) from 1 to 99% by weight of a hydroxyphenyltriazine compound of formula (I) wherein R<SUB>1</SUB>, R<SUB>2 </SUB>and R<SUB>3 </SUB>are each independently of the others C<SUB>1</SUB>-C<SUB>18</SUB>alkyl; C<SUB>2</SUB>-C<SUB>10</SUB>,alkenyl; or phenyl-C<SUB>1</SUB>-C<SUB>4 </SUB>alkyl; R<SUB>4 </SUB>is hydrogen; or C<SUB>1</SUB>-C<SUB>5</SUB>alkyl; and (b) from 99 to 1% by weight of a further UV absorber selected from the group of (b) hydroxyphenyltriazines that are different from component (a), (b<SUB>2</SUB>) benzotriazoles, (b<SUB>3</SUB>) dibenzoylmethane derivatives and (b<SUB>4</SUB>) camphor derivatives. The compositions are suitable as UV filters in cosmetic compositions
Patent JP-4347066-B2 (JP)
IPC: F25B17/08
Filed: 2003-04-15
Granted: 2009-10-21
Abstract: A solid sorption heat pump is provided that includes an adsorber/desorber unit including a heat exchanger and a solid sorption material. The adsorber/desorber unit is placed in a common housing, which is sealed against the outside atmosphere, together with a condenser/evaporator unit, and the adsorber/desorber unit and the condenser/evaporator unit are separated from one another by an adsorbant-permeable element. The adsorber/desorber unit includes a thermoconductive absorbent holding body, which is connected in a thermoconductive manner to the heat exchanger. The absorbant holding body holds the sorption material, and provides stability to the adsorber/desorber unit. The interior of the common housing is subjected to the action of a negative pressure. The common housing is provided as a thin-walled sheet metal sheathing that is placed on the absorbent holding body, whereby diverting the collapsing forces generated by the negative pressure to the holding body and/or to the heat exchanger and to the condenser/evaporator unit.
Patent JP-4693356-B2 (JP)
IPC: B60G17/017
Filed: 2004-03-09
Granted: 2011-06-01
Abstract: An operating process for a motor vehicle (1) level regulation unit comprises sensing the distance between the body and wheel axles and adjusting this to an ideal value if given limits are exceeded by activating actuators to equalize the level horizontally. Automatic leveling is stopped for safety reasons if inadmissible positions are detected.
Patent JP-4559216-B2 (JP)
IPC: C07K14/765
Filed: 2003-05-15
Granted: 2010-10-06
Abstract: The present invention is a method of purifying recombinant human serum albumin (rHSA) from a solution, which method comprises to subject a cell culture supernatant (CCS) comprising rHSA cation exchange on a bimodal high salt tolerant matrix; hydrophobic interaction chromatography (HIC); anion exchange; and recovering the purified rHSA. The bimodal high salt tolerant cation exchange matrix used enables performing a purification of a cell culture supernatant directly, in the sense that no further dilution thereof is necessary. Due to its high binding capacity, said bimodal cation exchange matrix also allows use of a smaller amount of matrix as compared to a corresponding conventional cation exchanger matrix. Accordingly, the present invention allows substantial savings as regards volumes and consequently operation costs.
Patent JP-4331677-B2 (JP)
IPC: A61M3/02
Filed: 2003-06-04
Granted: 2009-09-16
Abstract: The invention provides an ear irrigation device for injecting a fluid into an external ear canal extending between an external ear and a tympanic membrane. The external ear canal includes an outer portion extending inwardly from the external car and including cerumen-producing glands and an inner portion between the tympanic membrane and the outer portion. The ear irrigation device has a longitudinally extending body including an inward end and an outward end. Also, the ear irrigation device includes an obturator disposed at the inward end. The ear irrigation device is adapted to direct fluid out of the body away from the obturator and both transversely and towards the external ear when the inward end is positioned proximate to the inner portion of the external ear canal.
Patent JP-4511351-B2 (JP)
IPC: A61B1/00
Filed: 2003-07-16
Granted: 2010-07-28
Abstract: A system whereby a magnetic tip attached to a surgical tool is detected, displayed and influenced positionally so as to allow diagnostic and therapeutic procedures to be performed rapidly, accurately, simply, and intuitively is described. The tools that can be so equipped include catheters, guidewires, and secondary tools such as lasers and balloons, in addition biopsy needles, endoscopy probes, and similar devices. The magnetic tip allows the position and orientation of the tip to be determined without the use of x-rays by analyzing a magnetic field. The magnetic tip further allows the tool tip to be pulled, pushed, turned, and forcefully held in the desired position by applying an appropriate magnetic field external to the patient's body. A Virtual Tip serves as an operator control. Movement of the operator control produces corresponding movement of the magnetic tip inside the patient's body. Additionally, the control provides tactile feedback to the operator's hand in the appropriate axis or axes if the magnetic tip encounters an obstacle. The output of the control combined with the magnetic tip position and orientation feedback allows a servo system to control the external magnetic field by pulse width modulating the positioning electromagnet. Data concerning the dynamic position of a moving body part such as a beating heart offsets the servo systems response in such a way that the magnetic tip, and hence the secondary tool is caused to move in unison with the moving body part. The tip position and orientation information and the dynamic body part position information are also utilized to provide a display that allows three dimensional viewing of the magnetic tip position and orientation relative to the body part.
Patent JP-4490823-B2 (JP)
IPC: H04N7/24
Filed: 2003-09-19
Granted: 2010-06-30
Abstract: A method and apparatus for the handling of a recorded data stream and associated linear application is disclosed. Linear real-time playback of the data stream and running of the linear application is commenced from a starting point thereof. On entering a non real-time playback phase, select frames from the data stream are mapped using a mapping scheme to create an interactive trick play stream. Events from the linear application are mapped into the interactive trick play stream using the disclosed mapping scheme.
Patent JP-4741276-B2 (JP)
IPC: B23B51/00
Filed: 2005-04-20
Granted: 2011-08-03
Abstract: The invention relates to a cutting tool preferably intended for drilling of the type that comprises a rotatable basic body (4), as well as a replaceable cutting part or loose top (5), which is rigidly connectable to the basic body via a male/female coupling, which includes, on one hand, a female-like groove (11) formed in a front end of the basic body (4), which groove is delimited by a bottom surface (14) and two side surfaces (15), and on the other hand a male part (22) insertable into the groove and protruding rearward from the loose top (5), which male part has an end surface (23) and two flank surfaces (24). In the front part of the basic body (4), a forwardly open slot (12) is formed, which separates two elastically deflectable legs (13) with the purpose of holding the male part (22) clamped in the groove (11), in one of said end and bottom surfaces (23, 14), a seating (28) being formed for the receipt of a projection (27) on the second surface. According to the invention, the seating (28) is larger or wider than the projection (27) in order to enable the male part (22) of the loose top (5) to move a short distance reciprocatingly in the groove (11) and thereby allow self-centring of the loose top.
Patent JP-4186965-B2 (JP)
IPC: B26B19/14
Filed: 2005-07-26
Granted: 2008-11-26
Abstract: A main body (23a) of an inner blade (23) is inserted into an inner blade insertion hole (22d) of an inner blade frame (22) such that the main body (23a) can extend and retreat, a tip end cutting edge (23b) is pushed by a spring (24) such that it comes into contact with an inner peripheral surface (21a) of a slit outer blade (21), the main body (23a) of the inner blade (23) projecting outward from the inner blade insertion hole (22d) is bent rearward in a rotational direction (R), and the cutting edge (23b) of the inner blade (23) is located rearward of the main body (23a) in the inner blade insertion hole (22d) in the rotational direction (R). With this configuration, the cutting edge does not fall forward in the rotational direction, and no gap is generated between the cutting edge and the inner peripheral surface of the slit outer blade.
Patent JP-4592547-B2 (JP)
IPC: H04J13/00
Filed: 2005-08-24
Granted: 2010-12-01
Abstract: A transmission power control method for controlling a transmission power of an E-AGCH including an absolute transmission rate of uplink user data, which is transmitt ed from a cell controlled by a radio base station to a mobile station, includes: notifying, from a radio network controller to the radio base station which controls a serving cell, an offset between the transmission power of the E-AGCR and a transmission power of a DPCH, when the mobile station is performing a soft-handover with the serving cell and non-serving cells; determining, at the serving cell to which the offset is notified, the transmission power of the E-AGCH based on the notified offset; and transmitting, at the serving cell, the E-AGCH to the mobile station using the determined transmission power.
Patent JP-4391978-B2 (JP)
IPC: H04N1/405
Filed: 2005-10-18
Granted: 2009-12-24
Abstract: A system for generating a set of bit masks arrays is provided (350-0 to 350-255) where the bit mask arrays (350-0 to 350-255) are such that clusters of entries of different types are spread across each array and entries of different types within the arrays are either part of a larger cluster of entries of that type or are immediately adjacent to a cluster of entries of that type. When a multi-level image (200) is converted to a half-tone image (300) utilising the bit mask arrays (350-0 to 350-255) a half-tone image (300) which limits the occurrence of small isolated printed or unprinted areas is generated. The bit mask arrays (350-0 to 350-255) are therefore particularly suitable for use with laser printers (28,32) which have difficulty rendering half tone images which comprise small isolated printed and unprinted areas.
Patent JP-4451378-B2 (JP)
IPC: H04W84/12
Filed: 2005-11-08
Granted: 2010-04-14
Abstract: A setting information notifying method that enables safely and easily exchanging appliance setting information between appliances connected to a home network, the said method comprising steps of that: a portable data media is connected to a first appliance which provides a service in a communication network; the first appliance writes on the data media an appliance setting application which is used in notifying the appliance setting information to the other appliance, a host name of the first appliance, and a digital certification with a first cryptographic key; the data media is reconnected to a second appliance which uses the service of the first appliance; and the second appliance identifies a network address of the first appliance based on its host name, and establishes a cryptographic communication using the first cryptographic key over the communication network, and automatically sends the appliance setting information to the first appliance.
Patent JP-4665762-B2 (JP)
IPC: G01N33/543
Filed: 2004-07-28
Granted: 2011-04-06
Abstract: A substrate surface on which either a substance to detect analyte or an analyte  per se  is immobilized, which surface is formed by a treatment of substrate surface with a liquid which contains uncrosslinked polymer based on polyethylene glycol chain segment, said treatment conducted either simultaneously with the immobilization of said substance or analyte or after said substance or analyte has been immobilized on said surface. The non-specific adsorption of impurity protein or the like which is co-existent in sample for assay is significantly restrained.
Patent JP-4838586-B2 (JP)
IPC: G11B20/10
Filed: 2003-10-01
Granted: 2011-12-14
Abstract: The invention provides a method of recording management information on a recording medium having at least one temporary defect management area, characterized in that the method comprising: recording defect management information on one of the at least one temporary defect management area; and recording indication information being used to identify which area among the at least one temporary defect management area is full.
Patent JP-4375804-B2 (JP)
IPC: B60C9/00
Filed: 2006-01-20
Granted: 2009-12-02
Abstract: <P>PROBLEM TO BE SOLVED: To provide a pneumatic tire improved in durability during run-flat travelling without hindering riding comfort during normal travelling.  <P>SOLUTION: This pneumatic tire is provided with a pair of side reinforcing rubber layers 7 respectively having a crescent-shaped cross section inside a radial carcass 3 formed over from a butt-less part 5 to a side wall part 6. The reinforcing cord layer 8 formed by coating a polyketone fiber cord, which is formed by twisting a plurality of polyketone filament bundles and which satisfies condition of a formula (I) σ≥-0.01×E+1.2 and a formula (II) σ≥0.02 [in the formulas, σ means heat shrinkage stress (cN/dtex) at 177°C, and E means modulus of elasticity (cN/dtex) when 49 N load is applied at 25°C], with coating rubber in at least either of an area A formed over from a belt end part to the maximum width part of a tire side part and an area B formed over from a part near a bead core to a bead filler.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-4102835-B2 (JP)
IPC: G01N33/53
Filed: 2006-03-17
Granted: 2008-06-18
Abstract: Methods and compositions are provided for use of modified or intact phycobilisomes as extremely potent labels in sensitive monitoring kits (e.g., for blood contamination), specific binding assays (e.g., visual, photometric and fluorometric immunoassays) and optoelectronic devices (e.g., biosensors, photoelectric transducers).
Patent JP-5108248-B2 (JP)
IPC: C03B11/00
Filed: 2006-04-17
Granted: 2012-12-26
Abstract: There is provided a glass composition having a devitrification temperature of 1000° C. or below, a glass transformation temperature (Tg) of 535° C. or below and a specific gravity within a range from 3 to 4. The glass composition has a refractive index (nd) within a range from 1.60 to 1.75 and an Abbe number (nud) within a range from 50 to 60.
Patent JP-5010847-B2 (JP)
IPC: G02B27/01
Filed: 2006-04-19
Granted: 2012-08-29
Abstract: Described herein is a transparent-display device for motor vehicles, to be used for presentation of information to the driver and/or to the passengers, said device comprising a plurality of LED sources (2), addressable individually or in groups through a series of conductive paths (30), deposited on a transparent underlayer (1) and connected to a control electronics, in which: i) said LED sources (2) are integrated in the form of dice, i.e., of elements obtained by dividing up a semiconductor wafer and without package; ii) said dice are integrated on, and electrically connected to, said underlayer via technologies of the chip-on-board (COB) type; and iii) said transparent underlayer 1 is pre-arranged for being at least in part superimposed on the windscreen (40) of the vehicle, in such a way that at least part of the information (60) presented to the user is superimposed on the background (50), said background (50) being visible to the user through said windscreen (40).