baber/WOPTO huggingface dataset:
Patent CA-2479150-A1 (CA)
Inventor: JONES A BRIAN
IPC: C07D217/08
Filed: 2003-03-21
Abstract: Composés de formule (I) et sels acceptables sur le plan pharmaceutique et N-oxydes desdits composés. Dans la formule (I), A, B, D et E représentent C ou N à condition qu'un ou plusieurs de ces éléments représentent N, R?1¿, R?2¿, R?3¿, R?4¿, R?5¿ et R?6¿ représentent des substituants simples, n vaut 0 à 3 et y représente un groupe aryle, hétéroaryle, carbocyclyle ou carbocyclyle fusionné. Lesdits composés sont utilisés en tant qu'antagonistes de VR-1 pour traiter des états pathologiques ou des maladies dans lesquels la douleur et / ou l'inflammation prédominent. La présente invention concerne également l'utilisation de ces composés pour fabriquer des médicaments et des compositions pharmaceutiques contenant ces médicaments, ainsi que des méthodes de traitement à l'aide desdites compositions.
Patent CA-2479644-A1 (CA)
Inventor: SJOGREN ERIC BRIAN
IPC: C07D471/14
Filed: 2003-03-27
Abstract: Cette invention concerne les composés représentés par la formule (I) dans laquelle A, Z, Z?1¿, Y, R?1¿ et R?2¿ sont tels que définis dans la description, ainsi que des formulations pharmaceutiques, des méthodes de préparation et d'utilisation de celles-ci pour le traitement de maladies induites par la p38.
Patent CA-2482041-A1 (CA)
Title: 4-chromanone derivatives for treating cellular proliferative diseases and disorders
Inventor: MORGANS DAVID J C JR
IPC: A61K31/4178
Filed: 2003-04-11
Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
Patent CA-2483523-A1 (CA)
Title: Dry disconnect
Inventor: REID AARON
IPC: F16L37/373
Filed: 2004-10-01
Abstract: A dry break coupling assembly for interconnecting components of a fluid handling system. The coupling assembly includes first and second valves, each includes a rotatable valve element for opening and closing a fluid passageway within a valve body. The over-center clamp mechanism is for interlocking the first and the second valves when the valves are in a connected arrangement, allowing the valves to be easily disconnected when the valves are in a closed position, having a pair of projecting bars disposed on an outer surface of a body of a first valve and a pair of clamp assemblies disposed on a body of the second valve. Each clamp assembly includes a clamp arm having a hook end for engaging one of the projecting bars, and a clamp lever for actuating the hook end to engage or disengage the projecting bar. A  yoke assembly is for operatively locking the over-center clamp when the second valve is in an open position, and an automatic locking assembly on each valve for locking the valve into a closed position when they are disconnected.
Patent CA-2484997-A1 (CA)
Title: Substituted pyrazolo-pyrimidine-4-ones
Inventor: HOISCHEN DOROTHEE
IPC: C07D487/04
Filed: 2003-04-22
Abstract: The invention relates to compounds of formula (I), in which Q, R1, and R2 have the meaning indicated in the description, methods for the production thereof, and the use thereof as herbicides and/or nematicides.
Patent CA-2485721-A1 (CA)
Title: Drug delivery device and method for vaporization
Inventor: SONG SOONHO
IPC: A24F42/60
Filed: 2003-05-13
Abstract: Disclosed is a method and device for rapid heating of a coated substance which preferably includes a drug to vaporize for inhalation therapy. A device (10) in accordance with the present invention preferably includes a substrate (20) which has an interior surface (20a) surrounding an interior region and an exterior surface (20b) upon which the coated substance (15) is to be adhered.  Though the substrate is preferably metallic, it does not need to be. A  combustible element (16a.16b) is placed in the interior region of the substrate and a spark or resistance igniter is connected to the combustible element. The igniter is for initiating oxidation of the combustible element.  Preferably, the coated substance is vaporized inside of a housing (30) to allow the vaporized drug to aerosolize and be inhaled by a user.
Patent CA-2487929-A1 (CA)
Inventor: VAN DAMME HENDRIK SIBOLT
IPC: C12Q1/02
Filed: 2003-06-03
Abstract: The present invention relates to methods for screening of cellular responses of cellular components comprising:(a) providing cellular components on the surface of a substrate, said substrate having immobilized thereon an array of detector molecules;(b) delivering test compounds to positions on the substrate corresponding to the arrayed detector molecules on the surface of said solid substrate;(c) incubating said test compounds with said cellular components on the surface of the solid support, under conditions allowing the induction of cellular responses;(d) assaying said cellular responses; and,identifying and characterizing the cellular responses induced by said test compounds. The present invention further relates to the uses of said methods as well as microarrays and kits for carrying out said methods.
Patent CA-2490333-A1 (CA)
Title: Production method of dimethylamine
Inventor: HIROHATA JITSUO
IPC: C07C209/02
Filed: 2003-05-19
Abstract: Conventional zeolite catalysts for the preparation of dimethylamine from methanol or a methylamine mixture and ammonia have a disadvantage in that th e selectivity for dimethylamine is steeply lowered when the conversion of methanol becomes 95% or above. The invention aims at overcoming the disadvantage to thereby provide a novel zeolite catalyst attaining a higher selectivity for dimethylamine, a lower selectivity for trimethylamine, and a higher activity for methanol-consumption reaction. A process for preparing dimethylamine by conducting a reaction between methanol and ammonia, among methanol, a methylamine mixture, and ammonia, or between a methylamine mixtu re and ammonia in the presence of a zeolite catalyst in a vapor phase, wherein the reaction is conducted in the presence of a zeolite catalyst treated with a solution of an organophosphorus compound.
Patent CA-2493052-A1 (CA)
Title: Medical device for providing access
Inventor: KATHRANI BITEN KISHORE
IPC: A61B17/02
Filed: 2005-01-14
Abstract: The invention provides, in one embodiment, a multifunctional, multi-piece medical device and related method for providing access to an internal body cavity, such as for use with a vacuum lift shell. The device can include a cannula and a cannula extension. The device provides a conduit between the external environment and operative field inside the patient's body during medical procedures, including diagnostic, therapeutic and surgical procedures. The invention allows entry and exit of air or gas to help create and maintain the operative field.  The invention can be used to provide an open and unobstructed working path, and allows the operative space to be maintained at ambient conditions of pressure and temperature.
Patent CA-2495956-A1 (CA)
Title: Sulfonamides as potassium channel blockers
Inventor: MCNAUGHTON-SMITH GRANT ANDREW
IPC: A61K31/497
Filed: 2003-08-15
Abstract: Compounds, compositions and methods are provided which are useful in the treatment of diseases through the modulation of potassium ion flux through voltage-dependent potassium channels. More particularly, the invention provides sulfonamides, and compositions and methods utilizing sulfonamides that are useful in the treatment of diseases by blocking potassium channels associated with the onset or recurrence of the indicated conditions. Exemplary diseases treatable with the compounds, compositions and methods of the invention include sickle cell disease and glaucoma.
Patent CA-2496256-A1 (CA)
Title: Illumination device
Inventor: DOELL GERHARD
IPC: F21S8/00
Filed: 2005-02-08
Abstract: An electrical illumination device for generating saturated colors with at least two illumination units, the illumination units each having a discharge vessel with a low-pressure discharge and a phosphor coating on the inner wall of the vessel, characterized in that at least one illumination unit has a discharge vessel with a xenon fill and a dielectric barrier discharge (R, G, B).
Patent CA-2497826-A1 (CA)
Inventor: CANNON L EDWARD
IPC: G01N33/543
Filed: 2003-09-08
Abstract: L'invention concerne, entre autres, des traitements et des compositions permettant de modifier la régulation de la durée de vie et les réponses cellulaires à des maladies et des troubles par antagonisation de l'axe GH/IGF-1. L'invention concerne également des méthodes de criblage d'agents pouvant moduler l'axe GH/IGF-1.
Patent CA-2498362-A1 (CA)
Title: Automated system for high-throughput electrophoretic separations
Inventor: GONCALVES ANTONIO M
IPC: G01N27/447
Filed: 2003-09-10
Abstract: A cassette (10) is disclosed for use in performing electrophoretic separations on a solid substrate. The cassette includes reservoirs (16) for containing buffer, electrodes (20) for receiving electrical current and a substrate support (22). The cassette is designed to connect with external fluid and electrical sources. A method of conducting electrophoresis separation in both one and two dimensions using a cassette is also disclosed. Furthermore, a novel apparatus for use in performing electrophoresis separation is disclosed.  The apparatus is preferably of modular construction with a docking station for receiving a cassette.
Patent CA-2499931-A1 (CA)
Inventor: WANG YIQUN
IPC: A61M25/00
Filed: 2003-09-23
Abstract: Medical device components and processes are disclosed. For example, tube- shaped catheter components and processes of making tube-shaped catheter components are disclosed. Devices and systems, including medical devices and systems, such as catheters, containing tube-shaped catheter components are also disclosed.
Patent CA-2502768-A1 (CA)
Title: Projectile shooting toy
Inventor: HENRY ROBERT JUDE
IPC: A63H17/00
Filed: 2003-10-30
Abstract: A projectile shooting toy (10) comprises a body housing (20), a projectile delivery tube (110) formed with an interior of the housing and a motor driven projectile firing apparatus having a trigger (36) and projectile cannon (120) pivotally mounted to the body housing. Activation of the trigger causes the cannon to move from a stored position (122) to a deployed position (124), allowing a projectile (100) to enter an inlet (130) of the projectile cannon from the projectile delivery tube. Activation of the trigger further causes a firing ram (142) to abruptly strike the projectile and fire it from the cannon. In a preferred embodiment, the projectile shooting toy is in the form of a helicopter (12).
Patent CA-2502861-A1 (CA)
Title: Multi-axial, orthopaedic rod cross-link connector system for correcting spinal defects
Inventor: JOHNSON CHRISTIOPHER E
IPC: A61B17/70
Filed: 2003-10-28
Abstract: This invention relates to interconnection assemblies 10, 110, 174, 246, 300, 310, 330, 360, for use with spinal fixation systems to treat spinal defects. The interconnection assemblies can include various rod connecting members 12 , 14, 94, 98, 120, 176, 178, 196, 216, 248, 250, 275, 280, 302, 312, 314, 275, 334, 336, and interconnecting elements 16, 140, 180, 200, 332 to secure the rod connecting members to each other in a variable orientations and lengths. The interconnection assemblies can be adjusted to minimize interference with the spinal column, bony processes and associated neural, muscular and ligame nt components of the spine all the while exhibiting a low-profile. The interconnecting elements and related components can be provided as a completely assembled unit that does not inadvertently become disassembled prior to or during implantation.
Patent CA-2503035-A1 (CA)
Title: Method and circuit breaker for reducing arc flash during maintenance in a low voltage power circuit
Inventor: MATSKO JOSEPH J
IPC: H01H71/10
Filed: 2005-03-31
Abstract: Maintenance trip functions override the normal or specified trip functions of a low voltage circuit breaker to reduce pickup currents and/or time delays to effect faster trips, which reduces arc energy produced by faults during maintenance or testing on a live circuit breaker.
Patent CA-2504844-A1 (CA)
Inventor: MORALES HUGO
IPC: E21B41/00
Filed: 2003-10-21
Abstract: The present invention relates to a method of designing a hydraulic fracturing treatment in a subterranean reservoir comprising the steps of a) quantifying reservoir parameters including the bottomhole temperature and the formation permeability, b) assessing the temporary variation in temperature of the formation due to the injection of a treatment fluid and c) designing a fluid optimized for said temporary temperature.
Patent CA-2506290-A1 (CA)
Title: 17beta-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
Inventor: PARUCH KAMIL
IPC: A61P5/28
Filed: 2003-11-14
Abstract: In its many embodiments, the present invention provides a novel class of compounds as inhibitors of type 3 17.szlig.-hydroxysteroid dehydrogenase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with type 3 17.szlig.-hydroxysteroid dehydrogenase using such compounds or pharmaceutical compositions.
Patent CA-2507556-A1 (CA)
Title: A trailer for towing after a towing vehicle, a system comprising a trailer and a towing vehicle, and a method of steering a trailer around a turning point
Inventor: NEJSUM LARS
IPC: B62D13/04
Filed: 2003-12-02
Abstract: The invention relates to trailer (1) for towing after a towing after a towing vehicle, said trailer (1) comprising a frame (3) configured for carrying a load and having a front end with a coupling (5) configured for connecting the trailer (1) to the towing vehicle and allowing that the trailer (1) and the towing vehicle are able to assume mutually angular positions during turning about a turning point O; and a rear end.  The trailer also has a separate wheel frame (8) that is connected to the frame (3) by means (10) that allow a relative turning of the frame in relation to the wheel frame (8) during turning of the trailer about the turning point, said wheel frame (8) comprising oppositely arranged wheels (4) that support the trailer (1) during the towing and that are arranged at a distance from each other close to a respective longitudinally extending side of the frame (3); and actuator means (15) for producing said relative turning of the frame (3). The invention is characterized in that the connecting means (10) also allow a controlled transversal movement of the frame (3) in a direction towards or away from said turning point (O) simultaneously with said relative turning of the frame (3); and that the trailer (1) comprises actuator means (15) for producing said transversal movement of the frame (3).
Patent CA-2509787-A1 (CA)
Title: Medication administration system
Inventor: HAITIN DAVID
IPC: G16H20/13
Filed: 2002-12-12
Abstract: The present invention comprises a system and method for administering medications to a plurality of patients in a medication institution. A preferred system comprises a workflow program (70) for generating a schedule r, wherein the scheduler coordinates the administration of medications to the patients, a medicine cabinet (30), responsive to said scheduler, for storing medications and dispensing the medications to an authorized user for administration to the patients, the workflow program (70) providing the cabinet (30) with patient specific information relating to said dispensation of the medications including a physician order for each patient, and a medicine cart (50), coupled to the medicine cabinet (30), for instructing sa id authorized user in the administration of said medication to each of said patients. The cart (50) comprises a plurality of patient specific cart drawe rs (51) for storing the medication to be administered to each patient, wherein each cart drawer (51) remains unidentified as patient specific until the medication cart (50) receives said patient specific information, and a cart processor, wherein the cart drawers are filled with medicine from the medici ne cabinet for each patient associated with each patient specific cart drawer (51) in accordance with the respective physician order for each patient.</SD OAB>
Patent CA-2512433-A1 (CA)
Inventor: HAGA HIROYUKI
IPC: H03K17/082
Filed: 2004-01-07
Abstract: A switching circuit having a current detecting circuit for detecting a main switch current waveform in a form of a high-speed real time waveform and outputting it with a low impedance. The current detecting circuit of the switching circuit includes a main switch (11) the ON voltage of which exhibits a resistive characteristic. The gate of the main switch (11) is connected to a driver circuit (4). One of the drain and source of the main switch (11) is connected to a fixed potential (3), while the other is connected to a load circuit (2). The current detecting circuit of the switching circuit further includes a first resistor element (21) having a resistance value that is higher than the ON resistance of the main switch connected to the fixed potential; an auxiliary switch (12) having its source connected to the first resistor element; an amplifier (6) that compares and amplifies a voltage occurring at the first resistor element and the ON voltage of the main switch and outputs them to the gate of the auxiliary switch; and a second resistor element (22) connected to the drain of the auxiliary switch for causing the ON  current of the main switch to be amplified, thereby causing a voltage to occur.
Patent CA-2512689-A1 (CA)
Inventor: JARRETT BRYAN ROBERT
IPC: G01S13/92
Filed: 2004-01-09
Abstract: Systems and methods for measuring the speed and/or direction of a target such as a vehicle in a field of view. The speed of a vehicle is measured using distance measurements, phase measurements, or Doppler shift measurements using a single transducer side fire configured sensor. The speed of a vehicle can be measured using laterally spaced transducers in a side fire or off angle configuration and using a single transducer sensor in a forward fire configuration.
Patent CA-2512775-A1 (CA)
Title: Seal valve, connection port, mix-feed tube, connection device for liquid infusion, circuit and connection system for liquid infusion circuit that are for medical device
Inventor: TAKEUCHI TOSHIAKI
IPC: A61M39/26
Filed: 2004-01-08
Abstract: In a seal valve (20), a valve hole (20b) can be opened by pressing and deforming the seal valve (20) with the head of a male-type connection mouth, such as a mouth portion (401) of an injector (400), without making the head of the male-type connection mouth to penetrate through the seal valve (20). A  connection port, a mix-feed tube, a connection device for a liquid infusion circuit, and a connection system for a liquid infusion circuit use the seal valve with the feature described above, realizing a needle-less environment.
Patent CA-2513051-A1 (CA)
Title: Improved combustor and method of providing
Inventor: PATEL BHAWAN B
IPC: F23R3/28
Filed: 2005-07-22
Abstract: An improved gas turbine engine combustor includes a planar region in which manufacturing tolerances are improved and thus cost of the combustor can be reduced.
Patent CA-2514361-A1 (CA)
Inventor: WARTIAN GEORGE
IPC: E05F3/22
Filed: 2005-08-02
Abstract: A control assembly for use with a door closer on a swinging door. The control assembly has a housing adjacent to the door closer, a clip having an actuating and a locking tab, and a biasing member that yieldably biases the clip to a released position. The actuating tab can be actuated from outside of the housing to engage the locking tab with part of the door closer to maintain the position of the door. The locking tab can automatically be released from the door closer by further opening the door whereupon the biasing member returns the clip to its released position so that the door may close.
Patent CA-2515476-A1 (CA)
Inventor: TESAURO JAMES STANLEY
IPC: G06F3/048
Filed: 2004-03-05
Abstract: The present invention provides a mechanism by which the number of bits used to identify the WIDs for each of the color buffer and the overlay buffer may be programmed into the graphics adapter based on the currently active application environment. With the apparatus and method of the present invention, a programmable WAT color size selection device is provided in a RAMDAC of the graphics adapter. This programmable WAT color size selection device may be dynamically programmed to use varying bit splits of a WID from a WID buffer to obtain different indexes into a color WAT table and an overlay WAT table. In this way, different splits of, for example, an eight bit WID may be obtained based on the setting of the programmable WAT color size selection device such that varying color and overlay capabilities are obtainable dynamically.
Patent CA-2516389-A1 (CA)
Inventor: RAKIB SELIM SHLOMO
IPC: H04N7/16
Filed: 2004-02-26
Abstract: Circuitry and processed carried out thereby are disclosed for transmitting video~on-demand and interactive service data and other service data on an MPEG  multiplex and sending management and control data including conditional access EMM key data in-band in said MPEG multiplex in MPEG packets having the DOCSIS  PID. Processes to send conditional access data by sending ECM messages containing control words encrypted with session keys in said MPEG multiplex and sending EMM messages containing session keys encrypted with private set top box users keys are disclosed. The EMM messages are sent in-band in MPEG  packets having the DOCSIS PID to only the set top boxes that request them and which have ordered an encrypted service. A head end with routing/switching capability to route MPEG transport streams encapsulated in IP packets is also disclosed.
Patent CA-2516418-A1 (CA)
Title: 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-alkoxy-3-quinolinecarbonitriles for the treatment of ischemic injury
Inventor: BOSCHELLI FRANK CHARLES
IPC: A61P9/10
Filed: 2004-02-19
Abstract: Compounds of the Formula (I), wherein X is N, CH n is an integer from 1-3; and R' and R are independently, alkyl of 1 to 3 carbon atoms, and pharmaceutically acceptable salts thereof, with the proviso that when n is 1, X is not N; are useful for inhibiting vascular permeability caused by disease, injury, or other trauma.
Patent CA-2518646-A1 (CA)
Inventor: DUCK NICHOLAS B
IPC: C12N15/82
Filed: 2004-03-10
Abstract: Compositions and methods for conferring herbicide resistance to plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a polypeptide that confers resistance or tolerance to glyphosate herbicides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants. Compositions also comprise transformed plants, plant cells, tissues, and seeds. In particular, isolated nucleic acid molecules corresponding to glyphosate resistant nucleic acid sequences are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:3 or the nucleotide sequences set forth in SEQ ID NOS: 1 and 2.