baber/WOPTO huggingface dataset:
Patent CA-2622233-A1 (CA)
Title: Improved aav vectors produced in insect cells
Inventor: HERMENS WILHELMUS THEODORUS JO
IPC: C12N15/864
Filed: 2006-10-19
Abstract: The present invention relates to the production of adeno-associated viral vectors in insect cells. The insect cells therefore comprise a first nucleotide sequence encoding the adeno-associated virus (AAV) capsid proteins, whereby the initiation codon for translation of the AAV VP1 capsid protein is a non-ATG, suboptimal initiation codon. The insect cell further comprises a second nucleotide sequence comprising at least one AAV inverted terminal repeat (ITR) nucleotide sequence; a third nucleotide sequence comprising a Rep52 or a Rep40 coding sequence operably linked to expression control sequences for expression in an insect cell; and, a fourth nucleotide sequence comprising a Rep78 or a Rep68 coding sequence operably linked to expression control sequences for expression in an insect cell. The invention further relates to adeno-associated viral vectors with an altered ratio of the viral capsid proteins that provides improved infectivity o f the viral particles.
Patent CA-2630501-A1 (CA)
Inventor: WANG CHUNG-LIN
IPC: C23F11/00
Filed: 2008-04-29
Abstract: The present invention discloses a solderable aluminum-based material, wherein electron donors combine with the non-bonded atoms on the surface of an aluminum-based material. The bonding between the electron donors and the aluminum atoms on the surface generates a protective film to prevent from the formation of an aluminum oxide layer on the surface of the aluminum-based material. The present invention improves the conventional aluminum-based material, and has lightweightness, a low price, a high economic value, a high electric conductivity, a high thermal conductivity and a superior solderability. Thereby, a normal soldering, a total-face soldering or a double-side soldering can be easily performed on the solderable aluminum-based material of the present invention with a common soldering technology.
Patent CA-2631393-A1 (CA)
Title: Execution de pages dynamiques cote-serveur
Inventor: VERMA ABHISHEK
IPC: G06F9/46
Filed: 2006-10-23
Abstract: L'invention concerne un système (30) et un procédé d'exécution en une passe de pages dynamiques à travers plusieurs cycles de requêtes et de réponses. Le système (30) comprend un client (32) et un serveur (34) communiquant l'un avec l'autre. Un conteneur (35) logé dans le serveur gère les requêtes devant aboutir à la présentation d'une page dynamique (36). Le conteneur contrôle le traitement de la page dynamique et, si cette dernière exige des informations supplémentaires pour continuer le traitement, une requête intermédiaire (44) est transmise au client, qui renvoie une réponse intermédiaire (46) contenant lesdites informations supplémentaires. Un miniserveur de notification (38) reçoit la réponse intermédiaire et en transmet les informations à la page dynamique, de sorte que l'exécution puisse reprendre sans interruption.
Patent CA-2631823-A1 (CA)
Title: Ginger fraction for inhibiting human cyp enzymes
Inventor: BLECH STEFAN
IPC: A61K31/12
Filed: 2006-12-20
Abstract: The present invention relates to a process for preparing a ginger fraction, the fraction prepared by this process and the use thereof on its own or combined with drugs for inhibiting human cytochrome P450 (CYP) enzymes (particularly cytochrome P450 3A4, CYP3A4) for positively influencing the oral bioavailability and pharmacokinetics of active substances.
Patent CA-2631985-A1 (CA)
Inventor: CLARK VICTOR D
IPC: A61B19/00
Filed: 2006-12-07
Abstract: The present invention provides a medical system comprising an elongated medical device having a longitudinal lumen, such as a catheter or a needle, and a stylet configured to be inserted into and subsequently removed from the longitudinal lumen. The stylet is configured to have at least one indicator that indicates that the distal end of the stylet is about to exit the lumen as the stylet is being withdrawn during use. Each indicator alerts the user that the stylet is almost completely withdrawn from the lumen such that the user may take proper precautions and prevent the stylet from inadvertently and uncontrollably exiting the lumen. Each indicator may be located in the proximity of the distal end of the stylet and present either a visual, physical, or audible indication. Additionally, the present invention provides a method that indicates the longitudinal position of a stylet relative to an elongated medical device.
Patent CA-2637024-A1 (CA)
Title: Substituted imidazole derivatives, compositions, and methods of use as ptpase inhibitors
Inventor: QUADA JAMES C
IPC: A61K31/433
Filed: 2007-01-30
Abstract: The present invention provides imidazole derivatives of Formula (I-IV), methods of their preparation, pharmaceutical compositions comprising the compounds of Formula (I-IV), and their use in treating human or animal disorders. The compounds of the invention inhibit protein tyrosine phosphatase 1B and thus can be useful for the management, treatment, control, or the adjunct treatment of diseases mediated by PTPase activity. Such diseases include Type I diabetes and Type II diabetes.
Patent CA-2637393-A1 (CA)
Title: Medical devices having particle-containing regions with diamond-like coatings
Inventor: WEBER JAN
IPC: A61L31/08
Filed: 2006-11-03
Abstract: According to an aspect of the present invention, various medical devices, including implantable or insertable medical devices, are provided, which comprise at least one particle-containing region whose surface is at least partially coated with a diamond-like coating.
Patent CA-2638353-A1 (CA)
Title: Method and system for resource sharing
Inventor: RAO MICHAEL
IPC: G06F21/60
Filed: 2008-07-25
Abstract: Systems and methods for wireless systems provide a mechanism for resource sharing. In an embodiment, private informational content associated with a single user is accessed. Shared informational content associated with the single user and at least one other user is also accessed. The private informational content and the shared informational content are displayed on a same user interface for the single user. Other embodiments are described and claimed.< /SDOAB>
Patent CA-2639000-A1 (CA)
Inventor: LOUIE KENNY WAI-DOON
IPC: G06Q10/06
Filed: 2008-08-20
Abstract: A workflow management system provides a graphical user interface (GUI) tool that allows a user to create and/or edit workflow logic without requiring the re-writing and recompiling of the application software, and without interrupting the operability of the application software at any time. The GUI tool allows the user to simultaneously view and create and/or edit the corresponding application screen where the workflow logic is applied in the application software, while the user creates and/or edits the workflow logic. The user creates and/or edits the workflow logic by selectively combining the available parameters that are provided in spoken language syntax by a context sensitive menu. The workflow logic statements are made available for the application software to call at the appropriate times. The GUI tool works in conjunction with a dynamically configurable database.
Patent CA-2639220-A1 (CA)
Title: Engine starting system
Inventor: GRYBUSH ANTHONY F
IPC: F02N11/14
Filed: 2008-08-28
Abstract: An internal combustion engine including an electrical starting system which integrates several components into a single assembly for easier manufacture and operation of the engine. For example, a safety switch and key are integrated with the electric motor starting system. The starting system includes a starter motor having a drive member in selective driving relationship with the engine crankshaft, and also includes a key and a switch assembled to the starter motor. The switch includes a power connector and a key interface, and the key and key interface are together moveable between a first or "insert/remove"  position in which the key is selectively engageable and disengageable with the key interface, a second or "run" position in which the key is engaged with the key interface and the power connector is not in electrical communication with the starter motor, and a third or "start"  position in which the key is engaged with the key interface and the power connector is in electrical communication with the starter motor.
Patent CA-2639362-A1 (CA)
Title: Report database dependency tracing through business intelligence metadata
Inventor: OLSON JEFFREY J
IPC: H04Q3/64
Filed: 2008-09-02
Abstract: In one embodiment, the present invention provides a data stream reference module 250 that can enable a user to perform forward tracing, backward tracing, and tracing indirect dependencies in a data model and/or metadata model. The tracing is not necessarily along a common hierarchical level but can be from one level to another.
Patent CA-2641280-A1 (CA)
Inventor: HUNTER JIMMY DALE
IPC: B29C48/06
Filed: 2008-10-20
Abstract: Multiple conductor electrical power cords, signal transmitting wiring and cable is insulated with one or more layers or sheathing of a thermoplastic polymer composition with at least the outer layer of the composition containing contaminant resistant or combating agents that inhibit growth of biological contamination. The microbial resistant cord or wiring has particularly advantageous utility of power cords for use with appliances or electrical products in facilities that affect health, such as medical and food related facilities that require safeguarding against contaminating microorganism attack formation, or growth.
Patent CA-2641805-A1 (CA)
Inventor: SEEKINS EARL
IPC: B65G23/44
Filed: 2008-10-24
Abstract: This invention relates to a front transport for a check stand which has a combined front roller and motor and an idler roller at the rear end with a conveyor belt going around both rollers. The front transport has a mechanism for adjusting the tension and tracking of the conveyor belt which consists of two bolts on the front end of the front transport near each side for adjusting a shuttle on each in which a motor mount is secured. Each shuttle can be moved back and forth by turning the adjustment bolt. This front transport can have varying lengths as it has break points in the metal frame for reducing the size of the conveyor assembly.
Patent CA-2641897-A1 (CA)
Inventor: PIYABONGKARN DAMRONGRIT
IPC: F16H48/22
Filed: 2007-02-02
Abstract: A control system (50) for a vehicle having first and second wheels (28, 30) is provided that includes a differential apparatus (22) adapted to distribute torque between the first and second wheels (28, 30) and a traction controller (52) for controlling operation of the differential apparatus (22) from vehicle launch up to a predetermined vehicle speed. The traction controller (52) is configured to engage the differential apparatus (22) in a first operating state according to at least one vehicle operating parameter indicative of a low traction operating condition and to further control engagement of the differential apparatus (22) in a second vehicle operating state during the low traction operating condition according to a difference between an actual vehicle yaw rate and a predetermined target vehicle yaw rate. The control system (50) also includes a stability controller (54) for controlling engagement of the differential apparatus (22) at or above the predetermined vehicle speed.
Patent CA-2642833-A1 (CA)
Title: Free ngal as a biomarker for cancer
Inventor: MOSES MARSHA A
IPC: G01N33/574
Filed: 2007-02-16
Abstract: Uncomplexed neutrophil gelatinase associated lipocalin (NGAL) is present at increased levels in individuals with atypical ductal hyperplasia (ADH)3 a major risk factor for future breast cancer development; in individuals that have ovarian cancer; and in individuals that have breast cancer, both invasive and noninvasive. Accordingly, the present invention is directed to measuring uncomplexed NGAL levels in urine as a primary screen to determine if an individual is either at risk of developing, or has developed cancer, e.g., cancer of epithelial origin including breast and ovarian cancer.
Patent CA-2643273-A1 (CA)
Inventor: PETYT ADRIAN
IPC: G01N33/487
Filed: 2007-02-28
Abstract: A biosensor comprising a first and a second substrate and an incompressible element extending between two edges of a sample chamber present between the substrates.
Patent CA-2644483-A1 (CA)
Title: Methods for quantifying the risk of cardiac death using exercise induced heart rate variability metrics
Inventor: HADLEY DAVID MILTON
IPC: A61B5/364
Filed: 2007-03-01
Abstract: A method for assessing cardiac risks in a specific patient based on heart rate variability, comprising: 
providing heart activity data of a specific patient including a windowed time series related to heart rate variability during a heart rate exercise stress test; 
determining a frequency domain value across selected frequency ranges of the heart activity data in different ones of the windowed time series; 
and assessing the risk of a cardiac event based on the frequency domain value. In particular, both the frequency value based on the spectral slope and the aggregate power, based on the square root of the sum of the squares of the original time series, have been found highly predictive of cardiovascular death.
Patent CA-2644594-A1 (CA)
Title: Diagnosis and treatment of prostate cancer
Inventor: LOBERG ROBERT D
IPC: C07H21/04
Filed: 2007-03-01
Abstract: The present invention relates to compositions and methods for cancer diagnosis, treatment and research, including but not limited to, cancer markers and uses of cancer markers. In particular, the present invention provides compositions and methods for targeting MCP-1 in prostate cancer.
Patent CA-2644599-A1 (CA)
Inventor: FORSYTH JOHN R
IPC: F16H3/08
Filed: 2007-03-13
Abstract: An automated triple-clutch multi-speed transmission is adapted to transfer power from the engine to the driveline of a motor vehicle. The transmission includes a first clutch operable for establishing a releasable drive connection between the input shaft and a first driven shaft, a second clutch operable for establishing a releasable drive connection between the input shaft and a second driven shaft and a third clutch operable for establishing a releasable drive connection between the input shaft and a third driven shaft. A first constant mesh gearset is driven by the first driven shaft. A second constant mesh gearset is driven by the second driven shaft. A third constant mesh gearset is driven by the third driven shaft. First, second and third gearset clutches are operable for releasably drivingly coupling the first, second and third gearsets to a countershaft.
Patent CA-2645494-A1 (CA)
Title: Methods and compositions for making and using polymorphs of cinacalcet
Inventor: LIU BELLE BEI
IPC: C07C211/30
Filed: 2007-03-22
Abstract: The present invention is directed to methods and compositions for making and using a new polymorph of cinacalcet hydrochloride.
Patent CA-2645758-A1 (CA)
Inventor: OTTO GEOFF
IPC: C40B40/04
Filed: 2007-03-29
Abstract: Methods of producing substrates having selected active chemical regions by employing elements of the substrates in assisting the localization of active chemical groups in desired regions of the substrate. The methods may include optical, chemical and/or mechanical processes for the deposition, removal, activation and/or deactivation of chemical groups in selected regions of the substrate to provide selective active regions of the substrate.
Patent CA-2647315-A1 (CA)
Title: System and method of rebalancing a portfolio of separately managed accounts
Inventor: MA PAUL
IPC: G06Q40/00
Filed: 2007-03-26
Abstract: A system and method for rebalancing separately managed accounts utilizing sub-models. Sub-models can be generated automatically by analyzing the restrictions that exist on the individual accounts, or created manually by identifying particular stocks that might fall within a particular industry, sector or other arbitrary classification. An account can be classified as belonging to one or more sub-models. These sub-models allow for a more efficient rebalancing process by allowing transaction decisions to be made according to a particular sub-model rather than at the level of each individual account. These sub-models also allow for more efficient monitoring of large numbers of accounts by allowing analysis of account drift according to both restrictions associated with the account as well as the account's master model portfolio, rather than solely relative to the account's master model portfolio without incorporating the account's restrictions.
Patent CA-2648831-A1 (CA)
Title: Spiro- (tho) benzopyran-2, 4' -piperidine-and cyclohexane derivatives as inhibitors of specific cell cycle enzymes
Inventor: SPEVAK WALTER
IPC: C07D491/10
Filed: 2007-05-03
Abstract: The present invention relates to new heterocyclic compounds of general formula (1) wherein the groups R1 to R7, k, X and Y have the meanings given in the claims and specification, the isomers and salts thereof as well as the use thereof as medicaments. Background to the invention WO 01/36423 describes 3,4-dihydrospiro[chromene-2,4'-piperidine] derivatives for treating diseases of the central nervous system. Spirocyclic heterocycles as .delta.-opioid receptor ligands for treating pain and anxiety states as well as diseases of the gastrointestinal tract are known from WO 2005/033073. The aim of the present invention is to indicate new active substances which can be used for the prevention and/or treatment of diseases characterised by excessive or abnormal cell proliferation.
Patent CA-2649844-A1 (CA)
Title: Pharmacological modulation of positive ampa receptor modulator effects on neurotrophin expression
Inventor: LAUTERBORN JULIE C
IPC: A61K35/30
Filed: 2007-04-19
Abstract: Antagonists of group 1 metabotropic glutamate receptors (mGluR) potentiate the effect of positive AMPA receptor modulators on neurotrophin expression, such as brain-derived neurotrophic factor (BDNF). The findings described herein suggest a combinatorial approach for drug therapies, using both positive AMPA receptor modulators and mGluR antagonists, to enhance brain neurotrophism.
Patent CA-2651974-A1 (CA)
Inventor: CORRIVEAU SYLVAIN
IPC: A63F3/06
Filed: 2009-01-23
Abstract: A method for providing a poker-related game related broadcast show, comprising selecting players, providing each player with a medal indicative of a gaming position order, positioning the players at respective gaming surfaces according to the order associated with the medal provided at step, playing hands of the poker--related game until at least one player is eliminated, handing over the medal of the at least one eliminated player to a winning player and eliminating prizes in accordance with random selections made by the eliminated at least one eliminated player until only one player remains, the remaining player being identified as the grand winner, allowing the grand winner to bring back into play an eliminated prize for each medal possessed by the grand winner and allowing the grand winner to randomly select a prize.
Patent CA-2654075-A1 (CA)
Inventor: GLENN JAMES L
IPC: A47F7/19
Filed: 2009-02-13
Abstract: An organizer having a top panel and a bottom panel with side panels and a rear panel attached between the top panel and the bottom panel. At least one partition panel attaches to the side panels and rear panel so that the side panels, rear panel, top panel, bottom panel, and at least one partition panel define compartments within the organizer. Each compartment corresponds with an opening, wherein the bottom panel serves as a bottom wall for one compartment and wherein the at least one partition panel serves as a bottom wall for another compartment. At least one access panel moveably attaches to a front edge of at least one compartment and bottom wall. The access panel corresponds to a compartment and the opening for that compartment, the opening being located above the bottom wall to which the access panel is attached. The access panel is sized and shaped to pivot in a downward direction to an open position in which the corresponding opening of the corresponding compartment is open. The access panel also can pivot in an upward direction to a closed position in which the access panel substantially covers its corresponding opening.
Patent CA-2654212-A1 (CA)
Title: New chemical compounds
Inventor: SENNHENN PETER
IPC: A61K31/425
Filed: 2007-06-13
Abstract: The present invention enco mpasses co mpounds o f general formula (1) wherein R1, M1, L1 and Q are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or anomalous cell proliferation, and the use thereof for preparing a pharmaceutical composition with the above-mentioned properties.
Patent CA-2654895-A1 (CA)
Inventor: CRUTCHER BERNARD C
IPC: H01R4/50
Filed: 2007-07-25
Abstract: The electrical frame member (70) includes a first leg section (34), a conductor receiving section (74), and a wedge section (30). first leg section (34) is configured to be connected to an electrical isolator (26). The wedge section (30) is integrally formed with conductor receiving section (74) and comprises a wedge connector shell contact surface (75). The wedge connector shell contact surface (75) is angled relative to the conductor receiving section (74).
Patent CA-2656397-A1 (CA)
Inventor: HAN JUNG HOON
IPC: A01N65/00
Filed: 2007-08-31
Abstract: An antibacterial coating comprising a hydrophilic polymer and a hydrophilic water soluble antimicrobial is used to coat surfaces of perishable foods. In some embodiments, the coating is a mixture of gelatinized pea starch and thyme oil.
Patent CA-2657477-A1 (CA)
Title: Device for reducing the power demand for the propulsion of a ship
Inventor: MEWIS FRIEDRICH
IPC: B63H5/00
Filed: 2009-03-09
Abstract: A device (10) for reducing the power demand for the propulsion of a ship, and for broad-built or non-broad-built not-very-fast ships of any type is de-signed in such a way that the device (10), which is affixed to the hull (100) at a short distance upstream of the propeller, comprises a fore-nozzle (20) with fins or hydrofoils (30; 30a, 30b, 30c, 30d) that are arranged within the fore-nozzle, wherein the fore-nozzle, at the top, can be tilted forwards, pref-erably by up to 8°, on a horizontal transverse axis that extends through the centre of the fore-nozzle.
Patent CA-2658086-A1 (CA)
Title: Elevator rope slippage detecting device, and elevator apparatus
Inventor: SHIRATSUKI AKIHIDE
IPC: B66B5/02
Filed: 2004-05-28
Abstract: In an elevator apparatus, a pulley is provided in a hoistway.  A rope that moves together with the movement of a car is wound around the pulley. Further, the pulley is provided with a pulley sensor for generating a signal according to the rotation of the pulley.  The car is provided with a car speed sensor for directly detecting the speed of the car. A control panel is provided with: a first speed detecting portion for obtaining the speed of the car based on information from the pulley sensor; a second car speed detecting portion for obtaining the speed of the car based on information from the car speed sensor; and a determination portion f or determining the presence/absence of slippage between the rope and the pulley by comparing the speeds of the car as respectively obtained by the first and second speed detecting portions.
Patent CA-2658713-A1 (CA)
Inventor: MARCHAL GILLES
IPC: A61K39/00
Filed: 2007-07-25
Abstract: The invention relates to a recombinant vector comprising a mycobacterial FAP protein coding sequence under the transcriptional control of a promoter active under hypoxia conditions and its use for the prevention and the treatment of epithelial tumors.