baber/WOPTO huggingface dataset:
Patent AT-E252889-T1 (AT)
Inventor: MISHRA AWADHESH K
IPC: A61K9/10
Filed: 1999-08-18
Granted: 2003-11-15
Abstract: Irritation upon injection of a formulation containing propofol is reduced or substantially eliminated by administering a stable, sterile, and antimicrobial aqueous dispersion comprising a water-insoluble microdroplet matrix of mean diameter from about 50 nm to about 1000 nm consisting essentially of about 1% to about 15% of propofol, up to about 7% of a propofol-soluble diluent, and about 0.8% to about 4% of a surface stabilizing amphiphilic agent. The aqueous phase includes a pharmaceutically acceptable water-soluble polyhydroxy tonicity modifier. The propofol-containing dispersion is devoid of additional bactericidal or bacteriostatic preservative agents.
Patent AT-E256845-T1 (AT)
Inventor: CUOCCI BRUNO
IPC: F24C15/02
Filed: 1999-10-21
Granted: 2004-01-15
Abstract: A gasket in elastomeric material is described for the thickness of doors of domestic cooking ovens or household appliances in general on the door abutment surface (7) of which there are provided, possibly equally spaced apart from each other, anchoring wings or tongues (6, 8) protruding to the outside. The gasket is formed of an elongated element (1) of elastomeric material, as a known tubular section provided with a peripheral continuous wing (11) frontally projecting, with the back wall (1a) of the section showing, spaced apart from each other, elongated slots (3) obtained by removal of material, in each of which there is inserted a rigid member (2) with central through hole (5) and groove- or U-shaped contour (4) substantially matching with the slot edge.
Patent AT-E239539-T1 (AT)
Inventor: NIERS LOUIS ANTONIUS HUBERTUS
IPC: B01D35/143
Filed: 1999-12-30
Granted: 2003-05-15
Abstract: A filtering device including a casing with an inlet space for liquid to be filtered and an outlet space for filtered liquid; a substantially cylindrical filtering element of the disposable type, which is removably placed within the casing to function therein as a liquid permeable partition between the inlet space and the outlet space; a unique information containing micro circuit or chip provided in the filtering element, adapted to function as an identification label and cooperating with a receiver provided in the casing, so as to provide for a periodical or continuous exchange of information between the micro circuit and the receiver. The micro circuit is embedded, at a circumferential location, in an annular seal provided at a terminal edge of the cylindrical filtering element, the seal enabling the filtering element to sealingly engage an annular seat between the inlet space and the outlet space. The receiver is provided in the seat and includes a flat annular coil, the average diameter of which corresponds with that of the annular seal.
Patent AT-E277896-T1 (AT)
Inventor: CHANDRAMOULI SITHAMALLI V
IPC: C07C227/16
Filed: 1999-12-17
Granted: 2004-10-15
Abstract: Methods for stereoselective substitution in which a (mono or un)-alpha-substituted unprotected beta-amino ester compound or salt thereof is reacted with an aliphatic electrophile in the presence of a base selected from alkyl lithium compounds, lithium hydride, lithium amide, lithium dialkyl amides and alkali hexamethyldisilylamines.
Patent DE-20909114-T1 (DE)
Title: Cryosphäre
Inventor: LEE BEN
IPC: B65D81/02
Filed: 2020-12-08
Abstract: Gehäusebaugruppe für eine Tieftemperatur-Aufbewahrungsanlage, wobei die Gehäusebaugruppe Folgendes umfasst:ein erstes Gehäuse,eine erste Polsterkomponente, die mit dem ersten Gehäuse verbunden ist,ein zweites Gehäuse, das gegenüber dem ersten Gehäuse angeordnet ist, wobei das zweite Gehäuse dafür konfiguriert ist, sich mit dem ersten Gehäuse zu verbinden,eine zweite Polsterkomponente, die mit dem ersten Gehäuse verbunden ist,wobei das erste Gehäuse und das zweite Gehäuse dafür konfiguriert sind, ein Dewargefäß in denselben aufzunehmen.
Patent DE-117201-T1 (DE)
IPC: F24H3/04
Filed: 1984-02-15
Abstract: The high-power electric heating device is capable of heating gas mixtures such as a mixture of hydrocarbons and hydrogen to temperatures and pressures attaining 900 DEG  C. and 60 bar respectively. A central duct connects the gas mixture inlet to the outlet and is constituted by a plurality of superposed independently removable modules. Each module comprises a plurality of electric resistance elements formed by banks of adjacent metallic strips. A peripheral zone of the device contains power supply conductors connected to the modules. By means of passages in the form of slits between the central duct and the peripheral zone, a small fraction of the gas stream is permitted to flow within the peripheral zone.
Patent DE-644037-T1 (DE)
Inventor: MORET DE ROCHEPRISE BERNARD
IPC: B29C48/475
Filed: 1994-09-21
Abstract: The invention relates to a hollow body made of a fluororesin, especially PTFE obtained by pasty extrusion, having a degree of anisotropy less than 1, and preferably substantially equal to 0.5. In order to manufacture such hollow bodies, a powder of fluororesin, especially a powder of as-produced PTFE, is mixed with a lubricant; the mixture is compressed in order to obtain an isotropic compact tubular preform; the said preform is introduced into an extruding press; the preform is pushed back through a passage (18) of reduced cross-section in a die (4, 5) so as to form longitudinally oriented fibres; the said fibres are compressed on leaving the said passage (18) in an internal expansion chamber (21) having an enlarged cross-section, so as to orient the said fibres transversely; and the fibres are delivered through the exit orifice (15a) in the die (4, 15) in order to obtain a hollow body. <IMAGE>
Patent ES-2585129-T1 (ES)
Title: Una hoja, un procedimiento de fabricación y uso de una hoja como tapa para envases
Inventor: JOHANSEN PETER
IPC: B32B27/36
Filed: 2011-11-22
Abstract: Un procedimiento de fabricación de una hoja, en particular, para su uso como una tapa de hoja troquelada para recipientes, tales como recipientes de poliéster (PET), comprendiendo dicha hoja una hoja base de poliéster transparente (PET) (4), caracterizado porque la hoja (2) se hace recubriendo la hoja base de poliéster transparente (4) con una capa adicional (5), que se aplica encima de la hoja base de poliéster transparente (PET) (4) mediante la co-extrusión de una capa de poliolefina (5a) y una capa de soldadura de PET (5b) de poliéster amorfo, para formar la hoja (2).
Patent ES-2140359-T1 (ES)
Title: Control preciso de expresion genetica en celulas eucarioticas mediante promotores que responden a la tetaciclina.
Inventor: BUJARD HERMANN
IPC: C07K14/00
Filed: 1994-06-14
Abstract: ANIMALES TRANSGENICOS QUE PORTAN DOS TRANSGENES, EL PRIMERO CODIFICANDO UNA PROTEINA DE FUNCION TRANSACTIVADORA QUE COMPRENDE UN REPRESOR TET Y UN POLIPEPTIDO QUE SE ACTIVA DIRECTA O INDIRECTAMENTE EN CELULAS EUCARIOTIDAS, Y EL SEGUNDO QUE CONSTA DE UN GEN ENLAZADO OPERATIVAMENTE A UN PROMOTOR MINIMO ENLAZADO OPERATIVAMENTE A AL MENOS UNA SECUENCIA DE OPERADOR DE TET. MOLECULAS DE DNA AISLADAS, (POR EJEMPLO, VECTORES OBJETIVOS) PARA INTEGRAR UNA SECUENCIA POLINUCLEOTIDA QUE CODIFICA UN TRANSACTIVADOR DE LA INVENCION EN UNA LOCALIZACION PREDETERMINADA CON UN SEGUNDO OBJETIVO DE MOLECULA DE DNA MEDIANTE LA RECOMBINACION HOMOLOGA. ANIMALES TRANSGENICOS QUE POSEEN LAS MOLECULAS DE DNA DE LA INVENCION INTEGRADAS EN UNA LOCALIZACION PREDETERMINADA EN UN CROMOSOMA MEDIANTE LA RECOMBINACION HOMOLOGA. TAMBIEN SE MUESTRAN METODOS PARA REGULAR LA EXPRESION DE UN REGULADRO TET UNIDO A UN GEN DE INTERES MEDIANTE LA ADMINISTRACION DE TETRACICLINA O UN ANALOGO DE LA MISMA A UN ANIMAL DE LA INVENCION. EL SISTEMA REGULATORIO DE LA INVENCION PERMITE UNA ACTIVACION O MODULACION CONDICIONAL DE LA EXPRESION DE UN GEN DE INTERES EN UNA CELULA O ANIMAL ANFITRION.
Patent ES-2166744-T1 (ES)
Inventor: KALNISH GRIGORY IZESLAVOVICH
IPC: A21D2/38
Filed: 1999-03-05
Abstract: According to this method, the seeds previously cleaned and still having their germs are steeped in an aqueous medium (water or activated water with or without nutriments) in an amount of at least 0.6 liter per 1 kg of seeds until the acidity of the aqueous medium reaches 2 to 12 degrees and until the swelling rate of the seeds is characterized by their capacity, under compression, to flatten while loosing the undamaged germ. The aqueous medium where the seeds are steeped is drained and the seeds are ground in order to remove the liquid fraction which is not related to the humid seed mass thus obtained. The dough is kneaded until the target consistency is reached while adding the ingredients indicated in the recipe. The dough is then cut, allowed to rest for 15 to 50 minutes at 35-99° C. while maintaining humidity balance conditions in the dough-atmosphere system, and eventually baked is undertaken at 200 to 300° C., provided that during the first 15 to 200 seconds the dough is in a steam-saturated medium. The seeds can further be additionally washed before their grinding while the liquid fraction removed during the grinding process is used as an ingredient for the dough.
Patent CY-1111336-T1 (CY)
Inventor: MEDVEDEV ALEKSANDR ALEKSANDROVICH
IPC: C03B37/02
Filed: 2011-03-11
Abstract: (57) The invention relates to the production of continuous mineral fibres from earth material, glass and glass-containing materials. The inventive method for producing mineral fibres consists in forming an area for sampling a melt in a feeder where the melt has a density ranging from 2.7 to 3.8 g/cm<3>. The ratio between the height of the melt in a furnace and the heigh of the area for sampling the melt ranges from 1.4 to 50.0. The ratio between the surface area of the melt in the furnace and the surface area of a projection of the area for sampling the melt on a horizontal plane ranges from 10 to 6000. The application of said conditions and operation modes makes it possible to significantly reduce the breakage rate of fibres during drawing and to increase the output.
Patent CY-1113379-T1 (CY)
Title: Πεπτιδια κdr και εμβολια που τα περιλαμβανουν
Inventor: TAHARA HIDEAKI
IPC: A61K38/17
Filed: 2012-01-19
Abstract: Η παρούσα εφεύρεση παρέχει εννεαπεπτίδια επιλεγόμενα από πεπτίδια περιλαμβάνοντα την αλληλουχία αμινοξέων ΑΚΟΛ. ΑΡ. ΤΑΥΤ.: 2, 3, 5, 8, 11 ή 12• εννεαπεπτίδια ή δεκαπεπτίδια επιλεγόμενα από τα πεπτίδια που περιλαμβάνουν την αλληλουχία αμινοξέων ΑΚΟΛ. ΑΡ. ΤΑΥΤ.: 29, 30, 33, 34, 40 ή 46 και πεπτίδια με ικανότητα επαγωγής κυτταροτοξικών κυττάρων Τ στα οποία ένα, δύο ή περισσότερα αμινοξέα αντικαθίστανται ή προστίθενται στις προαναφερθείσες αλληλουχίες αμινοξέων, καθώς και φάρμακα για την αγωγή ή την πρόληψη όγκων, όπου τα φάρμακα περιλαμβάνουν αυτά τα πεπτίδια. Τα πεπτίδια της παρούσης εφευρέσεως μπορούν να χρησιμοποιηθούν ως εμβόλια.
Patent CY-1113288-T1 (CY)
Title: Ανασυνδυασμενοι φορεις που βασιζονται επι του τροποποιημενου ιου αγκυρας (mva) ως αποτρεπτικα και θεραπευτικα εμβολια εναντι aids
Inventor: HEENEY JONATHAN
IPC: C12N15/863
Filed: 2012-10-19
Abstract: Η εφεύρεση αφορά σε ανασυνδυασμένους φορείς, οι οποίοι βασίζονται επί του τροποποιημένου ιού Άγκυρας (MVA) ως αποτρεπτικά και θεραπευτικά εμβόλια έναντι AIDS. Οι εφευρετικοί ανασυνδυασμένοι ιοί περιέχουν αλληλουχίες, οι οποίες εισάγονται στην ίδια θέση εισαγωγής MVA και που επιτρέπουν την ταυτόχρονη έκφραση διαφόρων αντιγόνων μιας HIV-1 Env πρωτεΐνης που συνίσταται από gp120 πρωτεΐνη που έχει έλλειψη αλληλουχιών που αντιστοιχούν στην πρωτεΐνη gp41 και μια χιμαιρική πρωτεΐνη σύντηξης Gag, Pol και Nef. Οι προαναφερθέντες ιοί είναι σταθεροί και μπορεί να πυροδοτήσουν ανοσοαποκρίσεις έναντι μιας μεγάλης ποικιλίας αντιγόνων. Αυτοί οι ιοί έχοντας χιμαιρική πρωτεΐνη που προέρχεται από αλληλουχίες του HIV-1 είναι κατάλληλοι για την παρασκευή αποτρεπτικών ή θεραπευτικών εμβολίων έναντι AIDS, ιδιαιτέρως για χρήση ως πρωτόκολλα εμβολιασμού που περιλαμβάνουν διάφορες δόσεις και διαφορετικούς φορείς, όπως καταδεικνύεται με δοκιμασίες που διεξάγονται χρησιμοποιώντας άλλους φορείς από την εφεύρεση που έχουν την ίδια οργάνωση γονιδιώματος, αλλά μια χιμαιρική πρωτεΐνη που προέρχεται από αλληλουχίες παθογόνου SHIV.
Patent CY-1118351-T1 (CY)
Title: ΑΔΕΝΟΪΟΣ ΑΠΟΤΕΛΟΥΜΕΝΟΣ ΑΠΟ ΠΡΩΤΕΪΝΗ ΕΞΩΝΙΟΥ ΚΑΨΙΔΙΟΥ SAdV-39 ΑΔΕΝΟΪΟΥ Ε ΠΙΘΗΚΟΥ ΚΑΙ ΧΡΗΣΕΙΣ ΑΥΤΟΥ
Inventor: ROY SOUMITRA
IPC: A61K48/00
Filed: 2016-12-13
Abstract: Ένας ανασυνδυασμένος φορέας αποτελείται από αλληλουχίες αδενοϊού πιθήκου SAdV-39, -25.2, -26, -30, -37 και -38 και ένα ετερόλογο γονίδιο υπό τον έλεγχο ρυθμιστικών αλληλουχιών. Επίσης αποκαλύπτεται μια κυτταρική σειρά η οποία εκφράζει γονίδιο(α) αδενοϊού πιθήκου SAdV-39, -25.2, -26, -30, -37 και -383. Παρέχονται μέθοδοι χρήσης των φορέων και κυτταρικών σειρών.
Patent CY-1118453-T1 (CY)
Title: Αυτο-στηριζομενο καλωδιο και συνδυασμος αποτελουμενος απο μια διαταξη αναρτησης και τετοιο αυτο-στηριζομενο καλωδιο
Inventor: EFRAIMSSON LARS
IPC: H01B9/00
Filed: 2017-01-17
Abstract: Παρέχεται ένα αυτο-στηριζόμενο καλώδιο (2) αποτελούμενο από ένα εξωτερικό τμήμα (4) και ένα εσωτερικό τμήμα (6), καθώς επίσης και ένας συνδυασμός ενός αυτο-στηριζόμενου καλωδίου (2) και μιας διάταξης ανάρτησης (50). Το εσωτερικό τμήμα (6) αποτελείται από τουλάχιστον έναν μονωμένο αγωγό (8) και το εξωτερικό τμήμα (4) διαθέτει μια πρώτη εσωτερική επιφάνεια (10) και μια εξωτερική επιφάνεια (12). Η εξωτερική επιφάνεια (12) είναι διατεταγμένη να εμπλέκει με μια διάταξη ανάρτησης (14). Το εσωτερικό τμήμα (6) διαθέτει μια πρώτη εξωτερική επιφάνεια (16), η πρώτη εξωτερική επιφάνεια (16) σε στηρικτική επαφή ενάντια προς την πρώτη εσωτερική επιφάνεια (10). Το εξωτερικό τμήμα (4) αποτελείται από ένα εξωτερικό στρώμα (18) και μια μεταλλική ταινία (20) προσκολλημένη στο πρώτο εξωτερικό στρώμα (18). Το πρώτο εξωτερικό στρώμα (18) διαθέτει την εξωτερική επιφάνεια (12), και η μεταλλική ταινία (20) διαθέτει την πρώτη εσωτερική επιφάνεια (10). Η πρώτη εσωτερική επιφάνεια συνιστάμενη από μέταλλο και προσαρμοσμένη, κατά την διάρκεια τοπικού φορτίου, για εμπλοκή τριβής με το υλικό της πρώτης εξωτερικής επιφάνειας αυξάνει την αποτελεσματικότητα μιας λειτουργικής λαβής μεταξύ της πρώτης εξωτερικής επιφάνειας και της πρώτης εσωτερικής επιφάνειας. Έτσι, μια αυξημένη τριβή, στη πραγματικότητα μπορεί να επιτευχθεί μια εμπλοκή τριβής, όταν μια ακτινικά προς τα μέσα κατευθυνόμενη δύναμη, π.χ. από μια εξωτερικώς παρεχόμενη διάταξη ανάρτησης, εφαρμοσθεί επί του αυτο-στηριζόμενου καλωδίου.
Patent CY-1119503-T1 (CY)
Title: Δισκιο ανθεκτικο σε παραβιαση που παρεχει αμεση απελευθερωση φαρμακου
Inventor: SCHWIER SEBASTIAN
IPC: A61P25/26
Filed: 2017-10-26
Abstract: Η εφεύρεση αφορά σε ένα ανθεκτικό σε παραβίαση δισκίο που περιλαμβάνει υλικό μήτρας σε ποσότητα μεγαλύτερη από ένα τρίτο του συνολικού βάρους του δισκίου· και μία πλειονότητα σωματιδιακών υλικών σε μία ποσότητα μικρότερη από τα δύο τρίτα του συνολικού βάρους του δισκίου· όπου τα εν λόγω σωματιδιακά υλικά περιλαμβάνουν φαρμακολογικώς δραστική ένωση και πολυαλκυλένο οξείδιο· και αποτελούν ασυνεχή φάση εντός του υλικού μήτρας.
Patent CY-1121060-T1 (CY)
Title: Παραγωγα [1,2,4] τριαζολο[1,5-α] πυριμιδινης ως αναστολεις πρωτεασωματος πρωτοζωων για τη θεραπεια παρασιτικων νοσηματων οπως η λεϊσμανιαση
Inventor: BIGGART AGNES
IPC: C07D487/04
Filed: 2018-12-05
Abstract: Η παρούσα εφεύρεση παρέχει ενώσεις του Τύπου Α: ή ένα φαρμακευτικώς αποδεκτό άλας, ταυτομερές, ή στερεοϊσομερές αυτών, όπου οι μεταβλητές είναι όπως ορίζονται στο παρόν. Η παρούσα εφεύρεση παρέχει περαιτέρω φαρμακευτικές συνθέσεις που περιλαμβάνουν τέτοιες ενώσεις και μεθόδους χρήσης τέτοιων ενώσεων για θεραπεία, πρόληψη, αναστολή, ανακούφιση, ή εξάλειψη της παθολογίας ή/και της συμπτωματολογίας μιας ασθένειας που προκαλείται από ένα παράσιτο, όπως η λεϊσμανίαση, η ανθρώπινη αφρικανική τρυπανοσωμίαση και η νόσος Chagas.
Patent SI-1699301-T1 (SI)
Title: Cream filler composition, method for preparing such a creme filler composition and food comprising such a creme filler composition
Inventor: LANDAZURI THOMAS
IPC: A23P30/40
Filed: 2003-12-30
Abstract: The invention relates to a cream filler composition, which comprises: a lipid fraction composed of a vegetable oil having a SFI of 0 at room temperature, a saturated fat fraction representing between 0% and 5% w/w of the total lipid fraction and a partially hydrogenated fat fraction representing between 0% and 1% w/w of the total lipid fraction, a powder sweetener composition, and a wheat gluten fraction having an increase gliadin content compared to the natural gliadin content in wheat gluten. The invention relates further to a method for preparing such a cream filler composition and food compositions comprising such a cream filler composition.
Patent SI-1778036-T1 (SI)
Title: Hearing protection and/or loudspeaker element
Inventor: PFANNER ANTON
IPC: H04R1/00
Filed: 2005-08-12
Abstract: A hearing protection and/or loudspeaker element (1) is provided which includes a carrier part (2) arranged on a protective helmet (5) and a module (4) which can be actively connected to an outer ear of the wearer to act as a hearing protection and/or loudspeaker module. The carrier part (2) and protective helmet can be fixed to the head of the wearer. The module (4) which acts as the hearing protection and/or loudspeaker module can be adjusted in relation to the loudspeaker part (2) and shifted from a position of rest to a position of use. The module (4) itself is like a plug and is embodied as a part that covers the entrance of the human outer ear.
Patent SI-1941148-T1 (SI)
Title: Turbofan engine for stol aircraft
Inventor: DACRE MIKE
IPC: B64C29/00
Filed: 2006-10-25
Abstract: A module (10) for use with a bypass turbofan engine. The module comprises a hot flow channel through which the hot gas flow generated by the engine can flow and a bypass flow channel (14) through which the bypass air generated by the engine can flow. Part of the bypass air may be re-directed to be exhausted from the module at an angle relative to the longitudinal axis of the module so as to create vertical thrust. The hot flow channel may be separated from the bypass flow channel by a porous separator (12) that allows a degree of mixing between the hot gas flowing in the hot gas flow channel and the cold gas flowing in the cold gas flow channel.
Patent SI-2984262-T1 (SI)
Title: Magnetic hooking device for movable parts of furniture
Inventor: SALICE LUCIANO
IPC: E05F5/00
Filed: 2015-01-15
Abstract: The magnetic hooking device (10) is applicable to a movable part of a piece of furniture and it is hookable to a magnetic opening and/or closing device that is applicable to a fixed part of the piece of furniture; the hooking device (10) comprises a ferromagnetic element (11) with which at least one permanent magnet (12) is magnetically connected. The ferromagnetic element (11) is arranged together with the at least one permanent magnet (12) in a housing body (13) in such a manner as to be magnetically connectable with the opening and/or closing device.
Patent TR-201203732-T1 (TR)
Title: Opioid antagonistlerin topikal bileşimleri ve deri hastalıklarının bu bileşimler ile tedavisi için yöntemler.
Inventor: PISAK IBRAHIM MUSTAFA ISKENDER
IPC: A61K31/485
Filed: 2010-09-28
Abstract: Mevcut buluş, deri hastalıklarının tedavisinde bir opioid antagonisti ya da farmasötik olarak kabul edilebilir bir tuzunun etkili bir miktarının ihtiyacı olan bir hastaya topikal olarak uygulanmasını içeren yöntemlere ilişkindir.
Patent TR-201804106-T1 (TR)
Title: Ssb modülasyon i̇le paralel manyeti̇k rezonans görüntüleme i̇çi̇n tamamen sayisal çok kanalli rf veri̇ci̇
Inventor: FİLİZ ECE FİLCİ
IPC: G01R1/00
Filed: 2016-01-28
Abstract: Buluşta, paralel Manyetik Rezonans Görüntüleme (MRG) cihazı için tamamen sayısal, çok kanallı bir RF verici ortaya koyulmaktadır. MRG sinyal üretimi, modülasyonu ve amplifikasyonu sayısal olarak gerçekleştirildiği için her bir kanalın faz ve genlik ayarı birbirinden bağımsız olarak ve kolayca yapılabilmekte ve dolayısıyla tüm RF sinyal vericisi kanalları yeniden sayısal olarak konfigüre edilebilmektedir. Kanalların ayrı ayrı kontrolü, MRG içerisinde yer alan çok kanallı RF sargısı içerisinde yaratılan homojen manyetik alanla sağlanır. Homojen manyetik alan üretiminin yanı sıra, çok frekanslı MRG sinyal üretimi de mevcut buluş vasıtası ile çok yüksek frekans çözünürlüğü ile kolay bir hale getirilmektedir. Çoklu frekans, daha hızlı görüntü alımını sağlamaktadır ve bu vesile ile MRG operasyon süresi azalmaktadır. Çift Yan Bant (DSB) MRG sinyalinin istenmeyen bandını bastırmak amacı ile RF verici yapısı içinde Sayısal Weaver Tek Yan Bant (SSB) modülasyonu kullanılmıştır. MRG sinyal vericisi içinde yer alan güç yükselteci, istenmeyen yan bandı kuvvetlendirmez, bu vesile ile SSB modülasyonu daha yüksek güç verimliliğine ulaşmaktadır.
Patent DE-3650080-T2 (DE)
Inventor: CERAMI ANTHONY
IPC: C07K16/00
Filed: 1986-11-05
Granted: 1995-02-16
Abstract: The present invention relates to compositions and methods for inhibiting protein aging. Accordingly, a composition is disclosed which comprises an agent or compound capable of inhibiting the formation of advanced glycosylation end products of target proteins by reacting with the carbonyl moiety of the early glycosylation product of such target proteins formed by their initial glycosylation. Suitable agents may contain an active nitrogen-containing group, such as a hydrazine group, and may further be at least partially derived from amino acids. Particular agents comprise aminoguanidine,  alpha -hydrazinohistidine and lysine. The method comprises contacting the target protein with the composition. Both industrial and therapeutic applications for the invention are envisioned, as food spoilage and animal protein aging can be treated.
Patent DE-3650134-T2 (DE)
Inventor: WILLIAMS STUART KONRADD
IPC: A61L27/50
Filed: 1986-06-04
Granted: 1995-06-22
Abstract: A novel implantable prosthesis for implantation in human patients is disclosed which comprises a synthetic substrate and a Type IV/V collagen surface layer seeded with a confluent monolayer of autologous endothelial cells. In the preferred embodiment, a base layer of interstitial collagen is adhered to the substrate. The Type IV/V collagen surface layer is provided in a laminate comprising an intermediate layer of interstitial collagen which is covalently bound to the aforementioned base layer. A cross linking agent, such as glutaraldehyde, is utilized to covalently bind the interstitial collagen base layer to the substrate, and the collagen intermediate layer to the base layer. The cross linking agent is subsequently deactivated with a soluble peptide, such as lysine. Autologous endothelial cells, such as microvascular endothelial cells derived from adipose tissue, are then seeded at high densities on the pretreated graft material. Those cells adhere in suitable percentages within times compatible with most vascular surgical procedures, and, even more importantly, flatten on that surface to assume the appearance of a natural, cobblestone morphology. The subject surface is resistant to shear stress, and yields good results when tested as a vena cava implant in dog.
Patent DE-3689080-T2 (DE)
Inventor: VIZI SZILVESZTER
IPC: C07D401/04
Filed: 1986-05-23
Granted: 1994-01-27
Abstract: The invention relates to novel racemic or optically active berban derivatives of the general formula (I), whereinR' and R<sup>2</sup> represent independently from the other a hydroxyl, straight or branched chain alkoxy group having 1 to 6 carbon atoms or R' and R<sup>7</sup> together represent a C<sub>1-3</sub> alkylenedioxy group;R<sup>3</sup> and R<sup>4</sup> represent independently from the other hydrogen, straight or branched chain alkyl group, having 1 to 4 carbon atoms and optionally substituted by hydroxyl group, or a C<sub>2-6</sub> alkoxycarbonyl or cyano group; andR<sup>5</sup> represents hydrogen, straight or branched chain alkyl group having 1 to 6 carbon atoms, C<sub>1-7</sub> aliphatic or aromatic acyl group or C<sub>1-7</sub> alkylsulphonyl or arylsulphonyl group and a salt thereof, to pharmaceutical compositions containing them, to the use as well as to process for preparing the novel compounds.The compounds of the general formula (1) are selective a<sub>2</sub>-adrenergic receptor-blocking substances and thus, they may be used for the treatment of depressive illnesses.