baber/WOPTO huggingface dataset:
Patent PT-763036-E (PT)
Inventor: LAUFER STEFAN
IPC: C07D517/04
Filed: 1995-05-31
Abstract: PCT No. PCT/EP95/02077 Sec. 371 Date Mar. 28, 1997 Sec. 102(e) Date Mar. 28, 1997 PCT Filed May 31, 1995 PCT Pub. No. WO95/32970 PCT Pub. Date Dec. 7, 1995The present invention relates to heterocyclic compounds of the formula in which R1-R7, B, a and X have the meanings recited in the specification. These compounds are usable in the treatment of diseases of the rheumatoid variety and for the prevention of allergically induced diseases.
Patent PT-811073-E (PT)
Title: Use of immune modulators for making medicaments ot inhibit immune responses against co-administered recombinant viruses
Inventor: WILSON JAMES M
IPC: A61K39/235
Filed: 1996-02-23
Abstract: A method of reducing immune response during gene therapy is provided which involves co-administration of the viral vector bearing a therapeutic transgene and a selected immune modulator capable of inhibiting the formation of neutralizing antibodies and/or CTL elimination of the vectors upon repeated administration.
Patent PT-827500-E (PT)
Inventor: DAELE GEORGES HENRI PAUL VAN
IPC: A61P1/00
Filed: 1996-05-15
Abstract: The present invention concerns novel (2-morpholinylmethyl)benzamide derivatives having the formula the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein R1 is C1-6alkyl, C2-6alkenyl or C2-6alkynyl; R2 is hydrogen, halo or C1-6alkylsulfonylamino; R3 is hydrogen or C1-6alkyl; L is a radical of formula R4-C(=O)-Alk- (a); R5-C(=O)-N(R6)-Alk- (b); or R7-C(=O)-O-Alk- (c); wherein each Alk is independently C1-12alkanediyl; R4 is hydrogen, hydroxy, C1-6alkyl, C1-6alkyloxy, amino, mono- or di(C1-6alkyl)amino or an optionally substituted heterocyclic ring; R5 and R7 each independently are hydrogen, C1-6alkyl, C1-6alkyloxy, amino, mono- or di(C1-6alkyl)amino or an optionally substituted heterocyclic ring; R6 is hydrogen or C1-6alkyl; and aryl is phenyl or phenyl substituted with 1, 2 or 3 substituents selected from halo, C1-6alkyl or C1-6alkyloxy. It further relates to pharmaceutical compositions comprising them, processes for preparing said compounds and compositions, and the use thereof as a medicine, in particular in the conditions involving a decreased gastric emptying.
Patent PT-835362-E (PT)
Inventor: DRIVER RONALD WILLIAM
IPC: F01C21/10
Filed: 1996-06-05
Abstract: A rotary machine has a rotor (450) eccentrically mounted in a casing and having a plurality of vanes (206) connected to oscillating arms (209) via cranks (208), the cranks having elements (400, 401) pivotally embracing a radial outer end of arm (209). The arms (209) can be radial. The rotor (450) has outer parts (457, 458) connected to intermediate part (450) by grooves (453) and rings (452) resisting radial expansion. The rotary machine can be used in a fuel-injected engine for example to derive energy from the difference in air pressure between ambient and the inlet manifold. <IMAGE>
Patent PT-927560-E (PT)
Inventor: PAREL JEAN-MARIE
IPC: A61M37/00
Filed: 1998-12-17
Abstract: The instrument for the transfer of an active ingredient e.g. a medication into the eyeball, by iontophoresis, has a reservoir (15) for the medication which can be applied to the patient's eye. The reservoir has at least one active surface electrode (11) opposite an ocular tissue, at the periphery of the cornea (C). It also has a return electrode (12) and an electrical current generator. The return electrode is preferably in contact with the patient's closed eyelids (22,24). The reservoir has a number of compartments as ring segments, for different medications, each with its own active electrode.
Patent PT-971585-E (PT)
Inventor: GOLUB LORNE M
IPC: A61K31/00
Filed: 1998-01-15
Abstract: The invention is a method of inhibiting cancer growth, by inhibiting cellular proliferation, invasiveness, or metastasis, or by inducing cytotoxicity against cancer in mammals. The method employs 6-demethyl-6-deoxy-4-de(dimethylamino)tetracycline (CMT-3) and other functionally related chemically modified, preferably non-antibacterial, tetracycline compounds to inhibit cancer growth. The method is particularly effective to inhibit the establishment, growth, and metastasis of solid tumors, such as tumors derived from colon cancer cells, breast cancer cells, melanoma cells, prostatic carcinoma cells, or lung cancer cells.
Patent PT-983342-E (PT)
Title: Culture medium with soy bean extract as aminoacid source and no protein complexes of animal origin
Inventor: RAPPUOLI RINO
IPC: C12N1/21
Filed: 1998-05-28
Abstract: The invention relates to a medium for culturing pathogenic bacteria to produce an immunogenic factor. The medium comprises non-animal derived proteinaceous material. The invention also relates to the use of the medium to cultivate pathogenic bacteria, obtaining immunogenic factors from the bacteria being cultivated and preparing vaccines using the immunogenic factors.
Patent PT-989931-E (PT)
Inventor: BARRAY ALPHONSE
IPC: B29L22/00
Filed: 1998-06-11
Abstract: A blow molding apparatus and a nozzle operable to provide fluid into an interior of a blank. The blank is supported in a mold such that a neck of the blank emerges from a wall of the mold. The nozzle includes a nozzle tip and an opening that surrounds the neck of the blank. A peripheral edge of the opening comes to rest on the mold and a seal is provided between the opening and the mold. In one embodiment, the seal is held on the nozzle by a locking ring.
Patent SG-68585-G (SG)
Title: High pressure differential switch device
IPC: H01H35/26
Filed: 1985-09-17
Abstract: The invention relates to a switch device (10) which is actuated when a preselected fluid pressure differential is exceeded. A piston (52) exposed to the pressure differential carries a plunger (56) which contacts a lever arm (64) mounted on a shaft (60). A spring (82) normally prevents the shaft (60) from turning but is overcome when an excessive pressure differential is applied across the piston (52). A switch arm (96) mounted on the shaft (60) actuates the switch (104) in response to turning of the shaft (60).
Patent SG-84590-G (SG)
Title: Hair cutting machine,particularly an electric hair cutting machine
IPC: B26B19/06
Filed: 1990-10-22
Abstract: In a hair cutting apparatus, particularly an electric hair cutting apparatus, with a shearing head comprised of a shear plate and a cutting element as well as with a spacer comb adapted to be seated on the shearing head for sliding contact with the skin surface to be treated, with the position of the forward edge of the cutting element being adjustable relative to the skin surface, the spacer comb (3)-upon being seated on the shearing head (2) of the hair cutting apparatus (1)-is adapted to be coupled with the hair cutting apparatus by centrally controlled coupling members (10, 14, 23) cooperating with coupling members (16, 18, 24) of the comb to provide a coupling (13) between the body (7) of the hair cutting apparatus (1) and the spacer comb (3), the coupling members being adapted to move the said spacer comb into its individual ratchet positions producing different lengths of the cut. The coupling members (10, 14, 23) providing for coupling and uncoupling of the spacer comb 3 are controlled by a slide control (11) of the body (7) of the hair cutting apparatus (1) in which all functions of the hair cutting apparatus including enabling and disabling of the drive are incorporated.
Patent IE-780571-L (IE)
Title: Nuclide generator
IPC: A61N5/10
Filed: 1978-03-22
Abstract: Nuclide generators for preparing sterile and pyrogen-free radioactive solutions consist of a generator column which is provided with radiation shielding and connected to a container for eluting agent and has a connection to a container for eluate. The generator and the container for eluting agent are located in vessels with centering devices, wherein the generator column with its radiation shielding is located in a fixed position relative to the vessel between two centering devices and connected via a cannula to the container for eluting agent which is held in a recess of one centering device in a fixed position relative to the generator column. The other centering device has also a recess for guiding and holding the eluate container which is connected to the generator column via a cannula.
[US4188539A]
Patent IE-37552-L (IE)
Title: Electrolytic recovery of metals
IPC: C25C1/00
Filed: 1973-04-19
Abstract: 1362943 Electrolytic recovery of metals CYPRUS METALLURGICAL PROCESSES CORP 2 Feb 1973 [21 April 1972] 5225/73 Heading C7B Metals particularly of Groups IB, IIB, IVA, VA, VIA and VIII of the Periodic Table, e.g. Cu, Ag, Zn, Cd, Pb, As, Sb, Se, Fe, Ni or Co, are recovered from their sulphides and/or mixed sulphides by electrolysis of an aqueous acidic (pH below 3À9) solution of at least one metal halide e.g. Al, Cr, Cu, Fe, Mn, Ni, Zn or rare earth metal halide (Cl, Br, I or F) of concentration 0À5 N to saturation at between 50 and 105C, mixed with the particulate metal sulphide, preferably of particle size smaller than 60 US standard mesh, to dissociate at least some of it into metal ions and elemental sulphur. The metal may be recovered by electro-deposition on the cathode e.g. of steel, Cu, Pb or Al; the anode may be of graphite or coated Ti. A diaphragm cell may be used with anode current density above 12 ASF. FeCl 2 is preferred with chalcopyrite, marmatite or pyrrhotite ores; AlCl 3 with galena ores or Pb-Zn or Pb-Ag concentrates; and ZnCl 2 with Zn ores. The pH may be maintained with HCl. An alkali or alkaline earth metal chloride may be added to the solution.
[GB1362943A]
Patent IE-39112-L (IE)
Title: Automatic frequency corrector
IPC: H04L27/22
Filed: 1974-04-01
Abstract: Correcting device ensuring automatically, at the receiving end, an exact timing of the frequency demodulated at the rated value, that timing being necessary for the demodulation to be effected correctly, the correction being effected by a frequency servo-controlling based on an error signal extracted from a frequency discriminator, by means of a processing of decoded logic signals.
[US3919653A]
Patent IE-42673-L (IE)
Title: Production of amino acids
IPC: C07C227/32
Filed: 1976-04-08
Abstract: The technical problem of preparing amino acids from carbamyl derivatives thereof is solved by reacting such a derivative, which may have been converted to a salt, with an oxidising agent such as nitrous acid in the presence of a cation resin in the acid form.
[GB1490054A]
Patent IE-790892-L (IE)
Title: Relay latching apparatus
IPC: H01H50/32
Filed: 1979-08-08
Abstract: A latching arrangement for a plug-in type of electromagnetic relay employing an insulative mounting sub-base for receiving an insulative relay base. An elongated leaf spring carried by the insulative mounting sub-base and having its ends protruding beyond the top and bottom of the insulative mounting sub-base. A pair of inclined ears formed on the insulative relay base for engaging the ends of the elongated leaf spring and locking the plug-in relay to the insulative mounting sub-base. A spring biased push rod for deflecting the elongated leaf spring for causing its ends to retract and disengage the inclined ears to permit the relay to be unplugged from the insulative mounting sub-base.
[US4174508A]
Patent IE-790945-L (IE)
Title: Arylalkyl and aryloxyalkyl phosphonates; anti-viral agents.
IPC: C07F9/40
Filed: 1979-08-08
Abstract: Arylalkyl and aryloxyalkylphosphonates, useful as antiviral agents, are prepared by reacting an arylalkyl or aryloxyalkyl halide with a trialkyl phosphite, or with an alkali metal salt of a dialkyl phosphonate, trialkyl phosphonoalkanoate or dialkyl phosphonoalkanone.
[US4182759A]
Patent FI-820354-L (FI)
Inventor: MELIN KARL HARVID
IPC: E02F3/34
Filed: 1982-02-04
Abstract: Front end loader intended to be mounted on tractors and functioning in such a way that the length of the lifting arms (13) can be increased or reduced in connection with an alteration of the elevation of the lifting arms (13). The device includes a lifting arm (13) which is bent in angle and consists of a front end part (8) and a rear end part (9). These parts are moveable in relation to each other, thus permitting an elongation or a shortening of the lifting arm (13). The alternation of the length of the lifting arm (13) permits an adaption to different applications such when there are special requirements regarding lifting height or loading capacity.
Patent FI-853562-L (FI)
Inventor: ISAAC OTTO
IPC: A61K/
Filed: 1985-09-17
Abstract: Improved camomile extracts are obtained by extraction of fresh camomile flowers with aqueous lower alkanols and wthout a subsequent heat treatment.
Patent IE-32310-L (IE)
Title: Manufacturing curved glass
IPC: C03B23/031
Filed: 1968-08-26
Abstract: 1,235,464. Bending glass sheets. TRIPLEX SAFETY GLASS CO. Ltd., S. E. KAY, and J. PICKARD. 27 Aug., 1968 [5 Sept., 1967], No. 40600/67. Heading C1M. Glass sheets 7 are bent between dies 1, 2 and retained for a time sufficient to allow thermal equilization to take place. To this end the dies are heated, either by internal resistance heaters, or by similar heaters lining the walls of a compartment surrounding the dies. A conveyer 9 supplies the heated sheets from a furnace. By this thermal control spring-back is minimized. The dies may be of moulded refractory or have a non-stick surface (e.g. a paste containing either boron nitride or an organo-platinum which decomposes to metallic platinum). Alternatively a silica-fibre cloth may be used. A preliminary bending may be carried out for difficult bends. The sheet may subsequently be temper quenched.
[GB1235464A]
Patent IE-33551-L (IE)
Title: Access control equipment
IPC: G06Q40/00
Filed: 1969-08-27
Abstract: 1285444 Access control equipment SMITHS INDUSTRIES Ltd 29 Aug 1969 [30 Aug 1968] 41424/68 Headings G4T G4V and B4X Discloses access control equipment identical with that disclosed in Specification 1,285,443. The invention relates to the gaining of access being dependent upon a reading of a record made of the information carried by the token, rather than a direct reading of the information on the token.
[GB1285444A]
Patent IE-891249-L (IE)
Title: Reducing puckering in a stitching machine
IPC: D05B81/00
Filed: 1989-04-18
Abstract: The apparatus incorporates a number of flexible filamentary stitch-engaging elements (2 or 12 or 17) arranged side by side in close juxtaposition as an endless row of stitch-engaging elements movable in a direction longitudinally of the row of stitch-engaging elements and positioned so that a portion of the row of stitch-engaging elements projects permanently across the line of stitching (5 or 15) at the sewing position. As sewing proceeds at least one stitch-engaging element is always in place below each stitch as it is formed and is then withdrawn as the work piece advances taking with it the stitch-engaging element thus leaving a gap below the stitch.
[WO8910442A1]
Patent IE-841691-L (IE)
Title: Nail polish remover
IPC: A61K8/00
Filed: 1984-07-03
Abstract: The fingernail water removal activity of aqueous acetone based polish removers is lowered by incorporating therein an amine salt of an anionic amidized hydrolyzed collagen, preferably in combination with an acid addition salt of amidized trialkylamine cationic surfactant.
[US4485037A]
Patent IE-861875-L (IE)
Title: Poly-4-aminopyrrole-2-carboxamido derivatives
IPC: C07D403/14
Filed: 1986-07-14
Abstract: The invention relates to poly-4-aminopyrrole-2-carboxamido derivatives of the following formula <IMAGE> wherein, subject to certain provisos, n is zero or an integer of 1 to 4; R is a) -NHR3, wherein R3 is a') -CON(NO)R4, in which R4 is C1-C4 alkyl either unsubstituted or substituted by halogen; or b') -CO(CH2)m-R5, in which R5 is halogen, oxiranyl, methyloxiranyl, aziridinyl, cyclopropyl or the residue of alicyclic, alpha , beta -unsaturated ketone or lactone, and m is zero or an integer of 1 to 4; b> <IMAGE> wherein either R6 and R7 are the same and are each oxiranemethyl, aziridinemethyl, or C2-C4 alkyl 2-substituted by halogen or by a group -OSO2R8, wherein R8 is C1-C4 alkyl or phenyl, or one of R6 and R7 is hydrogen and the other is as defined above; c) -NO2; d) -NH2; or e) -NH-CHO; each group R1 is, independently, hydrogen or C1-C4 alkyl; R2 is a C1-C6 alkyl group terminating with a basic or acidic moiety or with a free or glycosilated hydroxy group; and the pharmaceutically acceptable salts thereof. The scope of the invention includes also pharmaceutical compositions comprising compounds of the above formula and a process for preparing same. The compounds of the invention can be useful antiviral and antineoplastic agents.
[GB2178036A]
Patent IE-40321-L (IE)
Title: Tool for trimming rubber
IPC: B23C5/08
Filed: 1974-09-16
Abstract: A rasp for the scraping of worn rubber tires has a generally cylindrical body composed of a multiplicity of blades peripherally adjoining one another, the blades being sandwiched between a pair of end disks held together by an axial bolt and bridged by axially extending rods which traverse at least two mounting holes in each blade. The blades may have a polygonal shape, with three or more toothed sides, overlapping one another so that one toothed side of each blade comes to lie along the periphery of the body to define part of a cutting surface. Additional apertures in the blades serve for the circulation of air therethrough, these apertures being flanked by lugs integral with the blades which are bent out laterally to form spacers therebetween; the end disks may also be apertured to facilitate air cooling of the body. Each blade tooth is bounded by four concave arcuate edges defining three sharp points, the middle point projecting radialy beyond the two flanking points; each tooth, or each pair of adjacent teeth, is symmetrical about a radial line.
[US3927447A]
Patent IE-872218-L (IE)
Title: Nicotinamide derivative as a therapeutic agent
IPC: A61P25/28
Filed: 1987-08-19
Abstract: An agent for the treatment of disorders associated with cerebral ischemia which comprises N-(2-hydroxyethyl) nicotinamide nitrate as an active ingredient.
[US4870090A]
Patent IE-46169-L (IE)
Title: Thiazolidine, thiazine and morpholine carboxylic acids and¹esters
IPC: A61K31/54
Filed: 1977-11-25
Abstract: The novel compounds of the general formula I, and their salts, are suitable for alleviating or eliminating angiotensin-induced hypertension. These compounds are prepared by acylating a compound of the formula II with a compound of the formula III. The symbols which are used in the formulae are defined in the claims. The compounds of the formula I in which R4 is a hydrogen atom can be oxidised to the corresponding disulphides. <IMAGE>
[GB1578940A]
Patent IE-832503-L (IE)
Title: 1,2,3,4-tetrasubstituted naphthalenes
IPC: C07D213/71
Filed: 1983-10-26
Abstract: Psoriasis in mammals is relieved by topically administering naphthalenes of the formula:wherein:R<sup>1</sup> and R are lower alkoxy or lower alkylthio;R<sup>3</sup> is hydrogen, lower alkyl, lower alkoxy, optionally substituted phenyl, optionally substituted phenyl lower alkyl, optionally substituted phenyl lower alkoxy, amino, lower alkylamino, lower dialkylamino, halo, cyano, or S(O)<sub>n</sub>R wherein R is lower alkyl; optionally substituted phenyl; optionally substituted phenyl lower alkyl; or optionally substituted heterocyclic aryl of three to nine ring atoms containing one or two heteroatoms selected from the group consisting of nitrogen, oxygen and sulfur, and the pharmaceutically acceptable acid addition salts thereof; and n is 0, 1 or 2; andW is alkyl of one to seven carbon atoms.
Patent IE-812509-L (IE)
Title: Azetidinone derivatives.
IPC: A61P31/04
Filed: 1981-10-27
Abstract: Antibacterial activity is exhibited by  beta -lactams having a sulfate substituent in the 1-position and an acylamino substituent in the 3-position.
Patent IE-852707-L (IE)
Title: Measuring the colour of a material such as paper
IPC: G01N21/86
Filed: 1985-11-01
Abstract: A system is provided for measuring the color of a sample material, and the system includes means for illuminating the sample and a sensor to measure light from the sample. The system also includes sample backing means to receive light transmitted by the sample and reflect the light back to the sample.
[EP0181155A2]
Patent IE-42382-L (IE)
Title: Cyclic amino acids
IPC: A61P25/20
Filed: 1975-12-15
Abstract: The present invention is concerned with new cyclic amino acids and with the preparation thereof.
[US4024175A]
Patent IE-822752-L (IE)
Title: Benzopyranyl alkanoic acid
IPC: C07D311/30
Filed: 1982-11-18
Abstract: The invention concerns [oxo-4-4H-[1]-benzopyran-8-yl]-alcanoic acids and their derivatives, their manufacture, represented by the formula. <IMAGE>   where AR is hydrogen, a phenyl radical which may or may not be substituted thenyl, furyl, naphthyl, a lower alkyl, cycloalkyl, aralkyl radical; B is a linear or branched lower alkyl radical, either saturated or ethylinically unsaturated; R1 is hydrogen or a phenyl radical; X is hydrogen or a lower alkyl or alkoxy radical and n=1, as well as salts, esters, aminoesters and amides. Compounds and their derivatives may be used as medicines, in particular in the control of tumors.
Patent IE-832858-L (IE)
Title: Time division automatic exchange
IPC: H04Q11/04
Filed: 1983-12-05
Abstract: The invention concerns exchanges switching telephone traffic, and in particular digital exchanges which have tie-lines passing therethrough. The exchange comprises control units (UC) and terminal units (UT) which are microprocessor controlled and which are connected to a switching network (RCX) by two-way multiplex links (MU). Some of the terminal units are connected to handle respective PCM junctions. At least one of the terminal units is a mixer and separator unit (UTB) which receives the signalling channels and in particular the signalling channels associated with the tie lines. This mixer and separator unit serves to forward signalling channel information for the tie lines. The terminal units connected to PCM junctions which include tie lines send the tie line signalling to the mixer and separator terminal unit, and also receive said signalling from said mixer and separator unit for onward transmission over a destination PCM junction.
Patent IE-863253-L (IE)
Title: 2-imidazolin-2-yl fused heteropyridine derivatives
IPC: C07D495/04
Filed: 1986-12-12
Abstract: There are provided novel (2-imidazolin-2-yl) fused heteropyridine compounds, and intermediate compounds for the preparation thereof, and a method for controlling a wide variety of annual and perennial plant species therewith.
Patent IE-894203-L (IE)
Title: Eneral delivery universal port assembly
IPC: A61J1/00
Filed: 1989-12-28
Abstract: An enteral delivery universal port assembly fabricated from a first portion (13) and a second portion (14) of different materials. The first portion (13) has a generally cylindrical side wall (15), an annular top surface (25) and a corresponding annular bottom surface. The second portion (14) has a central portion (35) with a peripheral flange (47) extending radially outward therefrom, and an annular portion (40) positionable in superposed adjacent relationship to the annular bottom surface of the first portion (13). Extending upwardly from the surface (45) of the central portion (35) are first and second projections (55, 58), the first projection (55) having a base which is a spikable membrane (60) and the second projection (58) being associated with filter means (68) which allow air to enter the enteral nutritional product container to which the enteral delivery universal port assembly is secured in its operative embodiment.
[EP0380934A1]
Patent NO-781101-L (NO)
Title: Pallkonstruksjon.
Inventor: SVIRKLYS FERDINAND M
IPC: B65D19/00
Filed: 1978-03-30
Abstract: Pall.