Patent WO-2014067666-A1 (WO)
Title: Dental composition
Inventor: KLEE JOACHIM
IPC: C07D307/14
Filed: 2013-11-04
Abstract: A composition comprising a polymerizable compound of the following formula (I) A is a group of the following formula (II) wherein X 1  is CO or CS; X 2   is a single bond, CO, CS, CH 2 , or a group Z[X'Z'] k , wherein X' is an oxygen atom, a sulfur atom or NR, (wherein R is a hydrogen atom, a straight chain or branched C 1-16  alkyl group which may be substituted by a C 3-6  cycloalkyl group, a C 6-14  aryl or C 3-14  heteroaryl group, -COOM, -PO 3 M, -0-PO 3 M 2  or -SO 3 M, a C 3-6  cycloalkyl group which may be substituted by a C 1-16  alkyl group, a C 6-14  aryl or C 3-14  heteroaryl group, -COOM, -PO 3 M, -0-PO 3 M 2  or -SO 3 M, a C 6-14  aryl or C 3-14  heteroaryl group which may be substituted by -COOM, -PO 3 M, -O-PO 3 M 2  or -SO 3 M), Z is a straight chain or branched C 1-4  alkylene group, Z' is a bond, a straight chain or branched C 1-4  alkylene group, and k is an integer of from 1 to 50; is a monocylic, bicyclic or tricyclic cycloalkyl group having 3 to 20 carbon atoms or a monocylic, bicyclic or tricyclic heterocycloalkyi group having 2 to 20 carbon atoms and 1 to 4 heteroatoms selected from oxygen, sulfur and nitrogen atoms, which groups may be substituted with 1 to 3 groups selected from a C 1-16  alkyl group, - COOM, -PO 3 M, -O-PO 3 M 2  or -SO 3 M; R 1  is a hydrogen atom, -COOM, a straight chain or branched C 1-16  alkyl group which may be substituted by a C 3-6  cycloalkyl group, a C 6-14  aryl or C 3-14  heteroaryl group, -COOM, -PO 3 M, -O-PO 3 M 2  or -SO 3 M, a C 3-6  cycloalkyl group which may be substituted by a C 1-16  alkyl group, a C 6-14  aryl or C 3-14  heteroaryl group, -COOM, -PO 3 M, -O-PO 3 M 2  or -SO 3 M, a C 6-14  aryl or C 3-14  heteroaryl group which may be substituted by -COOM, -PO 3 M, - O-PO 3 M 2  or -SO 3 M, R 2  is a hydrogen atom, -COOM, a straight chain or branched C 1-16  alkyl group which may be substituted by a C 6-14  aryl or C 3-14  heteroaryl group, -COOM, -PO 3 M, -O-PO 3 M 2  and -SO 3 M, a C 3-6  cycloalkyl group which may be substituted by a C 1-16  alkyl group, a C 6-14  aryl or C 3-14  heteroaryl group, -COOM, -PO 3 M, -O-PO 3 M 2  or -SO 3 M, or a C 6-14  aryl or C 3-14  heteroaryl group which may be substituted by -COOM, -PO 3 M, - O-PO 3 M 2  and -SO 3 M, L is a single bond or an (n+1 ) -valent linker group; B independently is a group according to the definition of A, a group of the following formula (III) wherein X 1  independently has the same meaning as defined for X 1  in formula (II), CH 2 , or a group [X'Z] k , wherein X' is an oxygen atom, a sulfur atom or NH, Z is a straight chain or branched C 1-4  alkylene group, and k' is an integer of from 1 to 50; R 1  and R 2  are independent from each other and independently have the same meaning as defined for formula (II), a group of the following formula (IV) wherein X 2  independently has the same meaning as defined for X 1  in formula (III) wherein X 1  independently has the same meaning as defined for X 1  in formula (II), CH 2 , or a group [X'Z] k' , wherein X' is an oxygen atom, a sulfur atom or NH, Z is a straight chain or branched C 1-4  alkylene group, and k' is an integer of from 1 to 50; R 1  and R 2  are independent from each other and independently have the same meaning as defined for formula (II), R is a hydrogen atom, a straight chain or branched C 1-16  alkyl group which may be substituted by a C 3-6  cycloalkyl group, a C 6-14  aryl or C 3-14  heteroaryl group, -COOM, -PO 3 M, -O-PO 3 M 2  or -SO 3 M, a C 3-6  cycloalkyl group which may be substituted by a C 1-16  alkyl group, a C 6-14  aryl or C 3-14  heteroaryl group, -COOM, -PO 3 M, -O- PO 3 M 2  or -SO 3 M, a C 6-14  aryl or C 3-14  heteroaryl group which may be substituted by - COOM, -PO 3 M, -O-PO 3 M 2  or -SO 3 M, a group of the following formula (V) wherein X 3  is CH 2 , CO, -CH 2 CO-, CS, or -CH 2 CS-, R 1  and R 2  which are independent from each other and independently have the same meaning as defined for formula (II), or a group [ Z'X"] m E, wherein Z' is a straight chain or branched C 1-4  alkylene group, X" is an oxygen atom, a sulfur atom or NR, (wherein R is a hydrogen atom, a straight chain or branched C 1-16  alkyl group which may be substituted by a C 3-6  cycloalkyl group, a C 6-14  aryl or C 3-14  heteroaryl group, -COOM, -PO 3 M, -O-PO 3 M 2  or -SO 3 M, a C 3-6  cycloalkyl group which may be substituted by a C 1-16  alkyl group, a C 6-14  aryl or C 3-14  heteroaryl group, -COOM, -PO 3 M, -O-PO 3 M 2  or-SO 3 M, a C 6-14  aryl or C 3-14  heteroaryl group which may be substituted by -COOM, - PO 3 M, -O-PO 3 M 2  or -SO 3 M), E is a hydrogen atom, PO 3 M 2 , a straight chain or branched C 1-16  alkyl group which may be substituted by a C 3-6  cycloalkyl group, a C 6-14  aryl or C 3-14  heteroaryl group, -COOM, -PO 3 M, -O-PO 3 M 2  or -SO 3 M, a C 3-6  cycloalkyl group which may be substituted by a C 1-16  alkyl group, a C 6-14  aryl or C 3-14  heteroaryl group, -COOM, -PO 3 M, -O- PO 3 M 2  or -SO 3 M, a C 6-14  aryl or C 3-14  heteroaryl group which may be substituted by - COOM, -PO 3 M, -O-PO 3 M 2  or -SO 3 M, and m is an integer of from 1 to 10; and n is an integer of from from 1 to 6; wherein M which are independent from each other each represent a hydrogen atom or a metal atom; provided that in case L is a single bond, B cannot be a group according to the definition of A or a group of the formula (III) or (IV).