baber/WOPTO huggingface dataset:
Patent NZ-542139-A (NZ)
Title: Pyrimidin-4-one derivatives and their use as p38 kinase modulators
Inventor: DURLEY RICHARD
IPC: C07D239/00
Filed: 2004-03-29
Abstract: Disclosed is a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein L and M are independently selected from -O-, -CH2-, -S-, -N(R)-N(R)-, -C(=O)- and -SO2-, and the remaining substituents are as defined in the specification. The compounds are useful for treating diseases caused by unregulated p38 MAP kinase activity.
Patent NZ-543724-A (NZ)
Title: 8beta-hydrocarbyl-substituted estratrienes as selectively active estrogens
Inventor: PETERS OLAF
IPC: A61P25/28
Filed: 2001-04-12
Abstract: Disclosed are 8beta-Substituted estra-1,3,5(10)-triene derivatives of general formula I' in which its substituents are as described in the specification. These estratrienes are used as pharmaceutically active substances that have in vitro a higher affinity to estrogen receptor preparations of rat prostate than to estrogen receptor preparations of rat uterus and which in vivo preferably have a preferential effect on bone material as compared to uterus and/or a pronounced effect with respect to the stimulation of the expression of 5HT2a receptor and transporter. The invention further relates to the production of these compounds and to their use in therapy.
Patent NZ-544868-A (NZ)
Title: Dynamic wheel balance weight with flowing media attached to the outside of a tire rim
Inventor: FOGAL ROBERT D JR
IPC: B60B1/00
Filed: 2004-07-15
Abstract: A balancing system for a tire/wheel assembly and a method balancing tire/wheel assembly using the system is disclosed. One or more balance weights (10) are attached to the non-pressurized side of the tube well of the tire/wheel assembly or a rim flange of the tire/wheel assembly. Each weight includes a cartridge (20) with an interior chamber (30) at least partially filled with a flowable balance media (40). The cartridge (30) is longitudinally arcuate, at least when attached to the tire/wheel assembly, about an angle of 180 degrees or less. The one or more weights (10), in combination, extend less than 360 degrees about the rotational axis of the tire/wheel assembly when the weights are attached to the tire/wheel assembly.
Patent NZ-548663-A (NZ)
Title: Child carrier
Inventor: BARTLETT DOUGLAS JAMES
Filed: 2006-07-21
Abstract: A child carrier (100) comprising: a compartment (102) adapted to house one or more children; a media system (200) comprising a child screen disposed in the compartment for displaying images to the one or more children when present in the compartment and an adult screen oriented to display images externally of the compartment for viewing by an adult disposed outside of the compartment; a support system (104) for supporting the compartment upon a surface (106), the support system including a plurality of wheels; and an attachment assembly (112) for removably attaching the child carrier to a shopping cart (110) without use of tools.
Patent NZ-550777-A (NZ)
Title: Underwater air/mixed gas exhaust system
Inventor: SCHULTZ TRENT M
IPC: B63C11/16
Filed: 2004-07-12
Abstract: Disclosed is an underwater exhaust system for an underwater breathing apparatus. The system is configured to lower the exhalation effort and to direct water adjacent the exhaust valve to reduce the likelihood of water entering the system or gas free flowing from the system. The system includes an air regulator housing, at least one exhaust coupled to the air regulator housing and at least one bubble deflector coupled to the air regulator housing, the bubble deflector defining an air space on a water interface side of the exhaust. The bubble deflector has at least one air inlet passage.
Patent NZ-553939-A (NZ)
Title: Heterocyclic diamide insecticidal agents with cyclopropyl or cyclobutyl substituents
Inventor: O'SULLIVAN ANTHONY CORNELIUS
IPC: C07D409/14
Filed: 2005-10-10
Abstract: Disclosed are heterocyclic benzene diamide derivatives of formula I, wherein each of E and Z, which may be the same or different, represents oxygen or sulfur; B is cyclopropyl or cyclobutyl which may be mono- di-, or trisubstituted by halogen, C1-C4alkyl, hydroxyl, cyano, C1-C4alkoxy or C1-C4alkylthio; D is phenyl or an aromatic heterocycle such as a pyridyl or pyrazole moiety, the other substituents are as defined herein. Also disclosed is a pesticidal composition, which comprises at least one compound as defined above for controlling insects or representatives of the order Acarina. A process for the preparation of the above compounds is further disclosed.
Patent NZ-554975-A (NZ)
Title: Process for preparing halogenoalkylnitrates
Inventor: RIVOLTA ROMANO
IPC: C07C201/08
Filed: 2005-11-09
Abstract: Disclosed herein is a process for preparing halogenalkylnitrates of formula (I), wherein substituent's are as disclosed in the specification. Also disclosed is a solution comprising a compound of formula (I) and selected solvents as defined in the specification, characterised in that the compound of formula (I) is present in a concentration not higher than 20% by weight.
Patent NZ-564257-A (NZ)
Title: HCV inhibitors
Inventor: GRAUPE MICHAEL
IPC: C07K5/06
Filed: 2006-06-29
Abstract: Disclosed is a compound of Formula (I) e.g. 1-[2S-(3-tert-butylureido)-3,3-dimethylbutyryl]-4R-(7-methoxy-2-pyrazol-1-yl-quinolin-4-yloxy)-pyrrolidine-2S-carboxylic acid (1S-cyclopropylaminooxalylbutyl)amide wherein E, R1, X, R3, R2 and R4 as defined in the specification or a pharmaceutically acceptable salt thereof for treating hepatitis C infections in a patient.
Patent NZ-567541-A (NZ)
Title: Device for preparing hot water and coffee machine provided with such a device
Inventor: HUIBERTS JOHANNES THEODORUS EMERENTIA
IPC: A47J31/54
Filed: 2006-10-17
Abstract: A device (30) for preparing hot water in the making of a beverage is disclosed. The device (30) uses a pressure pump bypass (56) to improve the safety of the system. The device (30) is provided with a pressure pump (34) with a supply pipe (33) for supplying relatively cold water to the pressure pump (34). An outlet (35) connected to a heating pipe (37, 38) is in heat-exchanging contact with a heating body. An outlet valve (39) in the heating pipe (37, 38) controls the flow of water to a coffee holder (42) that accommodates a bed of coffee (43). The heating body comprises a reservoir (36) that is openly connected to the environment, a heating element (40) and water in the reservoir as a heat-exchange medium. A by-pass pipe (54) connects the inlet (57) and outlet (35) of the pressure pump (34) to each other with a pressure-operated valve (56). The reservoir (36) is connected with a cold water supply pipe (46) and with a hot water delivery pipe (47) for delivering hot water from the reservoir (36). The outlet valve (39) comprises an electrically-operated valve. An electrically operated delivery device (48) is incorporated into the hot water delivery pipe (47). A regulating device (55) is connected with the electrically operated valve and with the delivery device (48) for the operation thereof. The regulating device (55) is also connected with a user-operated selection unit (60) for selecting the operation of the outlet valve (39) or of the delivery device (48) in the hot water delivery pipe (47) .
Patent NZ-568647-A (NZ)
Title: One way valve assembly for releasing sterile flowable substance without backflow, with elastomeric membrane
Inventor: GREG PARDES
IPC: B65D5/72
Filed: 2006-11-03
Abstract: A one way valve assembly flows a sterile flowable substance from a source to an outlet orifice and prevents any backflow of contaminants through the one way valve assembly when the flowable substance ceases to flow. The valve assembly includes an elastomeric membrane which aids in preventing any backflow of contaminants when dispensing of the flowable substance is stopped.
Patent NZ-574332-A (NZ)
Title: Methods of treating surfaces with ionic organosilicon compositions
Inventor: METHA PRAKASH VITHALDAS
IPC: B05D3/00
Filed: 2006-08-22
Abstract: Disclosed is a method of treating an inorganic surface comprising applying to the surface an aqueous solution consisting essentially of at least one ionic organosilicon compound wherein the compound and its substituents are defined in the specification. Also disclosed is an article comprising an inorganic surface having a hydrophobic layer bonded to said surface such that said surface exhibits a water exclusion percentage from about 80 to about 100%, said hydrophobic layer comprising a polycondensate of a water soluble ionic organosilicon compound as defined in the specification.
Patent NZ-577811-A (NZ)
Title: Sanitary water conservation device
Inventor: DAVENPORT QUINTIN
IPC: E03C1/12
Filed: 2007-11-28
Abstract: Disclosed is an installation for the intermediate holding and storage of liquid, said installation comprising a sealable housing having an inlet for receiving said liquid and an outlet for discharging said liquid, a holding reservoir pivotally mounted and positioned within said housing to receive and temporarily store a quantity of said liquid, wherein said holding reservoir is an asymmetrically shaped open bucket adapted to automatically move about said pivot from a first position adapted for receiving and storing said liquid to a second inverted position where stored liquid is emptied into said housing under the influence of gravity once the accumulated liquid reaches a sufficient mass wherein said housing includes a tapered and inclined liquid race incorporated into the floor of said housing to divert said liquid directly to said outlet, wherein said race is tapered and inclined toward said outlet such that a two part flow is applied to said waste with most solid material exiting to said outlet in a first flow action and most fluids exiting to said outlet as a second flow action. Also disclosed is a sewerage system incorporating the above installation.
Patent NZ-578030-A (NZ)
Title: Method for detection of hop latent virus, primer set for the detection, and kit for the detection
Inventor: OKADA YUKIO
IPC: C12N15/00
Filed: 2007-11-26
Abstract: Provided is a detection method for hop latent virus that comprises an extraction step in which hop latent virus RNA is extracted from a specimen, an amplification step in which a primer set containing four different specified oligonucleotides is used for amplification of cDNA by Reverse Transcription-Loop-mediated isothermal AMPlification (RT-LAMP) using the RNA as template, and a judging step in which hop latent virus is judged to be present when amplification of the specific cDNA has occurred in the amplification step.
Patent NZ-580538-A (NZ)
Title: A method of baking and an oven, where the oven has a control means to deactivate a heating means after a time and a trip temperature
Inventor: WILLETT PAUL EATON
IPC: A21B1/02
Filed: 2009-10-20
Abstract: Disclosed are a baking oven (10) and a method of baking. The oven includes a chamber (11), supporting means (14), heating means (20), a sensor, an interface, and control means. The supporting means support one or more baking trays, and the heating means underlies the baking trays. The sensor provides the oven temperature to the control means, which is also connected to the interface and heating means, and deactivates the heating means after a specific time and temperature is reached. The interface receives a bake program and information of the product being baked.
Patent NZ-588589-A (NZ)
Title: Novel class of spiro piperidines for the treatment of neurodegenerative diseases
Inventor: BRODNEY MICHAEL AARON
IPC: A61P25/28
Filed: 2009-05-04
Abstract: Disclosed is a compound of formula (I), wherein the substituents are as defined in the specification. In particular, there is a NSO2N moiety in the spiro condensed 5 membered ring. The compounds are inhibt production of A-beta peptides and are useful in the treatment of Alzheimer's disease and other neurodegenerative and/or neurological disorders.
Patent NZ-589299-A (NZ)
Title: 2-[Heteroaryl]alkyl-1,2,3,4-tetrahydro-quinoline derivatives for the treatment of cancer etc.
Inventor: DIAMOND MARC
IPC: C07D215/12
Filed: 2009-04-24
Abstract: 589299 Disclosed are 2-[heteroaryl]alkyl-1,2,3,4-tetrahydro-quinoline derivatives as represented by the general formula (I), wherein: each R1 is independently selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, alkoxy, -OR4, -SR4, -NR4R5, cycloalkyl, heterocycloalkyl, aryl and heteroaryl; R2 is selected from the group consisting of hydrogen, alkyl, alkyl-OH, alkenyl and alkynyl; R3 is aryl, optionally substituted with from 1 to 3 R6 groups; R4 and R5 are each independently selected from the group consisting of hydrogen, alkyl, alkenyl and alkynyl; or R4 and R5 are combined with the nitrogen to which they are attached to form a heterocyclic ring having from 5 to 7 ring members and from 1 to 3 heteroatoms each independently selected from the group consisting of N, O and S; each R6 is independently selected from the group consisting of H, alkyl, alkenyl, alkynyl and alkoxy; L is a linker selected from the group consisting of alkylene, alkenylene, alynylene and cycloalkylene; X is a heteroaryl ring having from 5 to 6 ring members and from 1 to 3 heteroatoms each independently selected from the group consisting of N, O and S, optionally substituted with from 1 to 3 R8 groups; each R8 is independently selected from the group consisting of H, alkyl, alkenyl, alkynyl and alkoxy; and salts and hydrates thereof. Representative compounds include { 2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)-vinyl]-1-methyl-1,2,3,4-tetrahydro-quinolin-6-yl} -dimethyl-amine and { 2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)-ethyl]-1-methyl-1,2,3,4-tetrahydro-quinolin-6-yl} -dimethyl-amine. Further disclosed is a pharmaceutical composition comprising a therapeutically effective amount of a compound as defined above or salts or hydrates thereof, optionally in combination with a therapeutically effective amount of a compound selected from the group consisting of an anti-androgen and a LnRH agonist, for the treatment of prostate cancer, ovarian cancer, hepatocellular carcinoma, acne vulgaris, endometriosis, acanthosis nigricans, hypertrichosis, breast cancer, precocious puberty, polycystic ovary syndrome, benign prostatic hyperplasia, alopecia, hirsutism and hypersexuality/paraphilia.
Patent NZ-591361-A (NZ)
Title: Levered packing device to compress disposable gloves into a removable container for dispensing
Inventor: STOLLERY JONATHAN WILLIAM
IPC: B65B67/04
Filed: 2009-08-20
Abstract: A glove stacking apparatus (1, 201) for forming a stack of gloves (100, 285) to be packed into a box (64), the apparatus comprising a receptacle (26) for receiving the stack of gloves 100, the receptacle having: a perimeter wall (24, 25) for containing the stack of gloves; a floor (22, 222) within the perimeter wall for supporting the stack of gloves; and an opening (27) opposite the floor into which additional gloves (70) may be added to the stack of gloves (100, 285) and out of which the formed stack may be removed. The floor is movable relative to the perimeter wall (24, 25), so that, in use the floor (22, 222) may be moved relatively away from the opening (27) so that as gloves (70) are added to the stack of gloves, the perimeter wall continues to contain the stack of gloves; and the floor (22, 222) may be moved relatively toward the opening (27) to remove the stack of gloves (100, 285) from the receptacle (26) through the opening.
Patent NZ-593611-A (NZ)
Title: Modified factor vii polypeptides and uses thereof
Inventor: MADISON EDWIN L
IPC: C07K14/745
Filed: 2008-04-11
Abstract: Disclosed is a modified factor VII (FVII) polypeptide comprising a modification in a FVII polypeptide, allelic and species variant thereof or active fragments thereof, wherein the modification is an amino acid insertion, deletion or replacement at a position corresponding to position D196, K197 or K199, and wherein the replacement is by a hydrophobic or acidic amino acid selected from Val, Leu, Ile, Phe, Trp, Met, Tyr, Cys, Asp, and Glu, and the modified FVII polypeptide exhibits increased coagulant activity and/or increased resistance to inhibitors compared to an unmodified FVII polypeptide.
Patent NZ-593875-A (NZ)
Title: Method of converting biomass into a high sugar-content feedstock
Inventor: MEDOFF MARSHALL
IPC: C12P7/04
Filed: 2010-02-11
Abstract: Disclosed is a method of converting biomass to sugars, comprising: providing a cellulosic or lignocellulosic feedstock, mixing the feedstock with a fluid and a saccharifying agent form a solution or suspension, allowing the feedstock to convert to sugars (saccharify), and controlling the balance of fluid and feedstock, prior to and/or during saccharification, so as to obtain a total sugar content in the suspension or solution of at least 20 per cent by weight after saccharification. The method may also involve reducing the recalcitrance of the biomass by: irradiation with ionising radiation, mechanical treatment, chemical treatment, sonication, pyrolysis, oxidation, or steam explosion.
Patent NZ-594060-A (NZ)
Title: Racket string alignment tool
Inventor: ALEX MNICH
IPC: A63B51/12
Filed: 2009-12-15
Abstract: 594060 A racket string alignment device (10) for aligning crisscrossed strings forming the face of a sports racket. The device features a body (20) in a cup or hemispheric shape adapted for easy gripping by the palm and hand of a user. Projections (16) extending from an axle (22) engaged roller have distal ends adapted to easily engage within rectangles formed by the strings of the face and realign them. The axle is in floating engagement with the body to allow the body to tile while maintaining the axle substantially parallel to the face of the racket formed by the strings. Fluid applicators (34) may be located between the projections to apply emollient to the strings and the rollers may be in a kit form allowing them to be changed for different sized racket faces with different sized rectangles in the crisscross pattern.
Patent NZ-595343-A (NZ)
Title: A piston rod and a drug delivery device incorporating the piston rod, wherein the piston rod comprises at least two axially aligned guideposts configured to engage a drive member of the drug delivery device
Inventor: OAKLAND PHILIP
IPC: A61M5/315
Filed: 2010-03-26
Abstract: 595343 A piston rod (20) for a device and a drug delivery device (1) incorporating the piston rod is disclosed. The piston rod comprises an elongated member having a distal end and a proximal end, wherein the proximal end has at least two sets of guideposts (24), and at least one set has at least two guideposts that are in axial alignment with each other and are configured for transmitting axial and rotational forces from a drive member having at least one internal groove (38).
Patent NZ-609246-A (NZ)
Title: Rotor blade with heating device for a wind turbine
Inventor: LENSCHOW GERHARD
IPC: F03D11/00
Filed: 2011-10-31
Abstract: 609246 The disclosure relates to a wind turbine rotor blade comprising at least one electrically operable heating mat (400) which is fixed in the interior (200) of the rotor blade (100). Typically the heating mat is a silicone mat and is fixed with silicone to the interior of the rotor blade.
Patent NZ-610025-A (NZ)
Title: Anode assembly and method
Inventor: GLASS GARETH
IPC: C23F13/06
Filed: 2011-11-08
Abstract: A method of protecting steel in concrete using a sacrificial metal element (11) and an activator and a backfill (13) and at least one spacer (12) is disclosed. The method comprises the steps of forming an anode cavity (14) in the concrete (20) for the purposes of installing a sacrificial anode assembly therein, locating the sacrificial metal element and activator (11 coated with the activator) in the backfill (13) in the anode cavity, spacing the activator away from the sides of the anode cavity with the spacer (12), and passing a current from the sacrificial metal element to the steel in the concrete to protect the steel (16) in the concrete with at least one conductor (17) connected to the sacrificial metal element. The backfill is a pliable and viscous backfill and does not harden before the installation process is complete. The backfill accommodates the products of sacrificial metal dissolution, and the sacrificial metal element comprises a metal less noble than steel. The at least one spacer is a resilient spacer placed in compression. A steel reinforced concrete protector for use in the above described method is disclosed. The steel reinforced concrete protector comprising an anode assembly and a separate backfill. The anode assembly comprises a sacrificial metal element (11) and an activator and at least one spacer (12) and the at least one spacer includes a plurality of outwardly extending members that extend away from the centre of the sacrificial anode assembly to an outer limit, and the at least one spacer defines at least one space between the activator and a line connecting two adjacent outer limits of the outwardly extending members, and the sacrificial metal element comprises a metal less noble than steel, and the backfill is a pliable and viscous backfill to fill the space defined by the at least one spacer and the activator.
Patent NZ-631340-A (NZ)
Title: Immunomodulatory agent and uses therefor
Inventor: THOMAS RANJENY
IPC: A61P19/02
Filed: 2013-03-25
Abstract: Disclosed is a method for treating or preventing joint damage in a subject with early rheumatoid arthritis (RA) or incipient RA, the method comprising, consisting or consisting essentially of eliciting an antigen specific tolerogenic response to an aggrecan polypeptide in the subject, thereby treating or preventing the joint damage.
Patent NZ-706407-A (NZ)
Title: Dental device
Inventor: COOPERSMITH ALLAN
IPC: A61C17/22
Filed: 2013-10-02
Abstract: A dental device for interdental cleaning which can be easily manufactured, the dental device comprising: a handle, a stem, the stem having a tip with an end. The tip has a first groove winding therearound extending from a first distal point proximate the end towards the handle at least one complete turn around the tip to a first-groove termination point. The stem has a first flange projecting outward therefrom and winding therearound. The first flange extends away from the handle from a first proximal point towards the end of the tip to a first-flange termination point. The first flange has a series of planar portions interconnected by a series of curved portions. At least a portion of the stem having the first groove and at least a portion of the first flange is suitable for insertion into an area between two teeth, whereby the area between the teeth may be cleaned by the at least a portion of the stem inserted between the teeth. Advantageously, the above flange configuration facilitates easier withdrawal of the device from a mould during manufacturing.
Patent NZ-711776-A (NZ)
Title: Mice expressing a limited immunoglobulin light chain repertoire
Inventor: MURPHY ANDREW J
IPC: C12N15/85
Filed: 2014-03-13
Abstract: A genetically modified mouse is provided, wherein the mouse expresses an immunoglobulin light chain repertoire characterized by a limited number of light chain variable domains. Mice are provided that present a choice of two human light chain variable gene segments such that the immunoglobulin light chains expresses by the mouse comprise one of the two human light chain variable gene segments. In a particular embodiment, a mouse comprises in its germline genome exactly two unrearranged human Vκ gene segments and five unrearranged human Jκ gene segments operably linked to a mouse light chain constant region at the endogenous kappa light chain loci of the mouse, wherein the exactly two unrearranged human Vκ gene segments are a human Vκ1-39 gene segment and a human Vκ3-20 gene segment. Methods for making bispecific antibodies having universal light chains using mice as described herein, including human light chain variable regions, are provided. Methods for making human variable regions suitable for use in multispecific binding proteins, e.g., bispecific antibodies, and host cells are provided.