baber/WOPTO huggingface dataset:
Patent SG-11201803645P-A (SG)
Title: Amine prodrugs of pharmaceutical compounds
Inventor: MARFAT ANTHONY
IPC: A61P25/16
Filed: 2016-11-17
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 26 May 2017(26.05.2017) WIPOIPCT (10) International Publication Number WO 2017/087594 A1 (51) International Patent Classification: A61K 47/48 (2006.01) A61P 25/16 (2006.01) A61K 9/14 (2006.01) (21) International Application Number: PCT/US2016/062400 (22) International Filing Date: (25) Filing Language: (26) Publication Language 17 November 2016 (17.11.2016) English (30) Priority Data: 62/257,533 19 November 2015 (19.11.2015) US (71) Applicant: BIOHAVEN PHARMACEUTICAL HOLD­ ING COMPANY LTD. [US/US]; 234 Church Street, Suite 301, New Haven, CT 06520 (US). (72) Inventor: MARFAT, Anthony; 333 Lantern Hill Raod, Mystic, CT 06355 (US). (74) Agents: VOLLES, Warren K. et al.; IPraxus Legal, LLC, P.O. Box 689, Old Lyme, CT 06371 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. English (§4) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) < Tf ON oo (54) Title: AMINE PRODRUGS OF PHARMACEUTICAL COMPOUNDS <N (57) : Disclose are amine prodrugs and methods of synthesis thereof. In particular, the amine prodrug comprises a drug mo - lecule and at least one or more prodrug appendage moieties and the method for synthesis the amine prodmg comprises a step of coupling the drag molecule and at least one or more prodrug appendage moieties. Also disclosed are exemplary riluzole prodrugs and methods of synthesis thereof. O
Patent SG-11201907049Y-A (SG)
Title: Process for treatment with a beam of ions in order to produce a scratch-resistant high-transmittance antireflective sapphire
Inventor: BUSARDO DENIS
IPC: C30B31/22
Filed: 2018-02-12
Abstract: PROCESS FOR TREATMENT WITH A BEAM OF IONS IN ORDER TO PRODUCE A SCRATCH-RESISTANT HIGH-TRANSMITTANCE ANTIREFLECTIVE SAPPHIRE Process for treatment of a sapphire part with a beam of a mixture of mono- and multicharged ions of a gas which are produced by an electron cyclotron resonance (ECR) source, where: - the voltage for acceleration of the ions is between 10 kV and 100 kV; - the implanted dose, expressed in ions/cm 2, is between (5 x 10 16 ) x (M/14) -1/2 and 10 17 x (M/14) -1/2 , where M is the atomic mass of the ion; - the rate of displacement V D, expressed in cm/s, is between 0.025 x (P/D) and 0.1 x (P/D), where P is the power of the beam, expressed in W (watts), and D is the diameter of the beam, expressed in cm (centimetres). A part made of sapphire having a high transmittance and which is resistant to scratching is thus advantageously obtained. [Figure 1]
Patent AT-398197-B (AT)
Title: Device for composting organic waste materials
IPC: C05F9/02
Filed: 1991-01-03
Granted: 1994-10-25
Abstract: In a device for composting organic waste materials, composed of a composting container which forms a degradation chamber and which is provided with a retention frame 63 for mobile transport and for its horizontal or sloping positioning and which is provided, on one end, with a charge port 66 for charging the container with the waste materials and with a discharge port 61 provided on the opposite end for discharging the compost and with an aeration device arranged inside the degradation chamber, the composting container consists of an elongated cylindrical tube 60 in which a worm conveyor 40 is rotatably arranged in the drive shaft 41 of which there is provided at least one air channel 45 as aeration device, which air channel is connected, on the one hand, to a compressed-air pump or a blower 8 and, on the other hand, to a plurality of air exit ports 44 which are arranged distributed along the drive shaft 41, thus allowing in particular an effective and rapid composting while avoiding aerobic zones in the degradation chamber. <IMAGE>
Patent HU-182091-B (HU)
Title: Process for producing 21-alkyl-pregnane derivatives and pharmaceutical compositions containing them
Inventor: CAIRNS JAMES
IPC: C07J9/00
Filed: 1980-01-21
Abstract: The present invention relates to novel 21-alkylated steroids of the pregnane series having the formula:
     wherein R 1  = alkyl (1-4 C); R 2  = carboxyacyl (1-18 C); X = H, F or Cl; Y = O, H(OH), H(lower acyloxy), H(F) or H(CI) with the proviso that Y is not H(F) when X is F; and the dotted line indicates the optional presence of a double bond, to processes for their preparation and to pharmaceutical compositions containing same. 
     The novel compounds possess strong anti-inflammatory properties, when applied locally and cause little or no systemic, thymolytic, adrenolytic and salt-retaining effects.
Patent HU-200250-B (HU)
Inventor: TOTH JANOS
IPC: H05B41/00
Filed: 1987-01-21
Abstract: A találmány tárgya elsősorban kisnyomású kisülő fényforráshoz, célszerűen fénycsőhöz (26) használható elektronikus előtét, amely a hálózati frekvenciánál legalább két nagyságrenddel nagyobb frekvenciájú váltakozó feszültséget előállító áramirányítót tartalmaz, melynek kimenete a fénycső (26) elektródáival (27,28) áll összeköttetésben. A továbbfejlesztés értelmében az áramirányító nyitózáróüzemű önrezgő együtemű ínverter és az ínverter kapcsolótranzisztorának (19) kollektorkörébe olyan légréses transzformátor pimer tekercse (18) van beiktatva, melynek menetszáma a szekunder tekercs (230 menetszámához a kapcsolási elrendezés tápfeszültségének és a kapcsolási elrendezés kimenetére csatlakoztatott fényforrás égésfeszültségének megfelelő arányban van illesztve, továbbá a transzformátor primer tekercsével (18) párhuzamosan záróüzemben feszültséghatárol ást végző kondenzátor (17) van bekötve, és az Ínverter kapcsolótranzisztorának (19) bázisa és emittere közé a kondenzátorból (12), transzformátor visszacsatoló tekercsből (13) és a kapcsolótranzisztor (19) bázisáramát meghatározó ellenállásból (16) álló, a kapA leírás terjedelme: 5 oldal, 2 ábra csolótranzisztor (19) záróirányú feszültségét biztosító soros tag van iktatva, és a transzformátornak a primer tekercs (18) és a kapcsolótranzisztor (19) kollektorának közős kivezetésével kapcsolódó, a fényforrás elektródáival (27, 28) villamosán összekötött ffitésmenetel (22,24)vannak  HU 200250A -1-
Patent HU-183326-B (HU)
Inventor: SZANTAY CSABA
IPC: A61P35/00
Filed: 1981-02-11
Abstract: Verfahren zur Herstellung von Apovincaminol-3´,4´,5´-trimethoxybenzoaten der allgemeinen Formel (1), worin R exp 1 eine Methoxygruppe oder ein Halogenatom und R exp 2 Wasserstoff, oder R exp 1 Wasserstoff und R exp 2 ein Halogenatom bedeuten, sowie deren Säureadditionssalze durch Umsetzung von 10-Methoxyapovincaminol mit 3,4,5-Trimethoxybenzoesäure oder einem zur Acylierung geeigneten Derivat dieser Säure. Die Verbindungen der allgemeinen Formel (I) und ihre Säureadditionssalze hemmen die Aktivität des Enzyms Phosphodiesterase und sind daher als Wirkstoff für Arzneimittelpräparate zur Behandlung von mit krankhafter Zellproliferation verbundenen Hautkrankheiten, insbesondere der Psoriase, geeignet. Formel (1)
Patent HU-217241-B (HU)
Inventor: HAMADA TATSUHIRO
IPC: C07D277/38
Filed: 1991-03-11
Abstract: Az iminő-tiazőlin-származékők (I) általánős képletében R1 jelentésehalőgénatőm, halőgénatőmmal szűbsztitűált 1–2 szénatőmős alkil-csőpőrt vagy halőgénatőmmal szűbsztitűált 1–2 szénatőmősalkőxicsőpőrt, R2 jelentése metilcsőpőrt, etilcsőpőrt, klóratőm,brómatőm vagy jódatőm, és R3 jelentése (1–6 szénatőmős alkil)-karbőnil-csőpőrt, benzil-karbőnil-csőpőrt, (3–4 szénatőmős alkenil)-őxi-karbőnil-csőpőrt, (3–4 szénatőmős alkinil-őxi)-karbőnil- csőpőrt,adőtt esetben 1–2 szénatőmős alkőxicsőpőrttal vagy fenilcsőpőrttalszűbsztitűált (1–6 szénatőmős alkőxi)-karbőnil-csőpőrt, adőtt esetbenmetilcsőpőrttal szűbsztitűált (3– 6 szénatőmős ciklőalkil)-karbőnil-csőpőrt, (3–6 szénatőmős ciklőalkőxi)-karbőnil- csőpőrt,benzőilcsőpőrt, N-(1–3 szénatőmős)-alkil-karbamőil-csőpőrt, fenőxi-karbőnil- csőpőrt, halőgénatőmmal szűbsztitűált (1–6 szénatőmősalkil)-karbőnil-csőpőrt vagy halőgénatőmmal szűbsztitűált 1–3szénatőmős alkil-szűlfőnil-csőpőrt, azzal a megkötéssel, hőgy ha R2 jelentése klóratőm, brómatőm vagyjódatőm, akkőr R1 jelentése halőgénatőm vagy halőgénatőmmalszűbsztitűált 1–2 szénatőmős alkilcsőpőrt, és R3 jelentése (1–6szénatőmős alkil)-karbőnil-csőpőrt, adőtt esetben fenil- csőpőrttalszűbsztitűált (1–6 szénatőmős alkőxi)-karbőnil-csőpőrt, benzőilcsőpőrtvagy fenőxi-karbőnil-csőpőrt. ŕ
Patent YU-48521-B (YU)
Inventor: ARH KOVACEVIC MIROSLAV DIPL ING
Filed: 1993-12-23
Abstract: Sistem za oblaganje fasada elementima od pečene gline, se montira - ugrađuje po ugradnji termičkog izolatora 16 preko podloge - nosećeg zida 14 i metalne potkonstrukcije 9, 10, 11, 12, 13 i 15 za nošenje fasadne obloge od pečene gline 100, 101, naznačen time, što se sastoji od fasadne ploče (100), linijskog bloka (101) o držača fasadne obloge (102); i što se montiraju - ugrađuju fasadne ploče (100) 9 linijski blokovi (101) u projektovani položaj horizontalnog ili vertikalnog sloga fasadne ploče, a pomoću dvojnih otvora (4) na bočnim površinama (2, 3) fasadne ploče (100), kanalima za prihvat držača fasadne obloge (6) na bazama linijskog bloka (6), kao i otvora na horizontalnom nosaču fasadne obloge (9), metalne potkonstrukcije, a po,oću veanog elementa, držača fasadne obloge (102) koji prodire kroz otvore (4 i 6') svojim telom (7), fiksira, razmiče i pravi otvorene spojnice po vertikali ili horizontali sa stabilizatorom -graničnikom držača (8) i podmetačem (8'). - Prijava sadrži još 3 zavisna patentna zahteva.
Patent ZA-91830-B (ZA)
Title: Neuroprotective 3-piperidino-4-hydrosychroman derivatives
Inventor: BUTLER TODD WILLIAM
IPC: C07D311/20
Filed: 1991-02-05
Abstract: 3-piperidino-4-hydroxychroman derivs. of formula (I) and their salts are new, where A and B = H or A with B = -CH2CH2-. X = CH2 or O. X1 = H or OH. Z = H, F, Cl, Br or OH. Z1 = H, F, Cl, Br or 1-3C alkyl. n = O or 1; m = 0 or 1-6. When X = 0 (I) pref has cis stereochemistry. (I) are prepd. by hydride redn. of a suitable alpha-aminoketone, using e.g. NaBH4 in THF at -15 to 15 deg.C.
Patent ZA-93794-B (ZA)
Title: Coating compositions, a process for their production and their use for coating water-resistant substrates.
Inventor: SCHWINDT JUERGEN
IPC: C08G18/62
Filed: 1993-02-05
Abstract: An aqueous two-component coating composition whose binder essentially comprises a combination of   a) a water-dissolved and/or -dispersed polyol component having a hydroxyl number of from 15 to 200 mg of KOH/g, comprising a1) at least one relatively high-molecular-weight, cationically modified, hydroxyl-containing paint resin and optionally a2) up to 10% by weight, based on a1), of a water-soluble reactive thinner, and b) a polyisocyanate component emulsified in the aqueous solution and/or dispersion of component a), in an equivalent ratio between the isocyanate groups of component b) and the active hydrogen atoms of the organic component a) of from 0.5:1 to 5:1, a process for the preparation of coating compositions of this type by mixing the said individual components, and the use of the coating compositions for the production of air- and/or heat-drying coatings.
Patent AT-394544-B (AT)
IPC: C02F11/02
Filed: 1987-05-15
Granted: 1992-04-27
Abstract: A device for the disposal and in particular the hygienic treatment of the sludge formed in a clarification plant has at least one reactor tank (6, 14) into which the sludge to be subjected to arerobic treatment is fed in batches. An aeration device (8) located in the reactor tank comprises a submerged motor, a disk-shaped blade wheel arranged approximately horizontally below the said motor and provided on its under side with approximately radial fins and a covering ring arranged below the blade wheel, a gap being formed between covering ring and blade wheel. Located above the blade wheel is an air channel connected to the atmosphere via an air suction pipe.
Patent AT-403095-B (AT)
Title: Solar radiation measuring sensor for global and diffuse radiation
IPC: G01J1/06
Filed: 1995-07-27
Granted: 1997-11-25
Abstract: The invention relates to a measuring instrument for solar radiation, which measures global radiation and diffuse radiation separately and quantitatively without using moving parts. A relatively large number 1..24 of small light-sensitive sensors of identical type (thermopiles or photodiodes) are arranged around a shadow-casting rod 25 in such a way that when the instrument is set up horizontally, at least one small sensor is completely shadowed, irrespective of the state of the azimuth of the sun. In the case of a simple straight rod, this criterion can be ensured only up to a solar height which grows with the length of the rod. By expanding the shadow rod by a crossbar 27, this requirement is ensured even for any desired solar heights. A glass dome 26 is used as a weather protection means. The sensors are scanned and evaluated cyclically via an analogue multiplexer. The evaluation can be carried out both electronically in the sensor housing and using software in a computer. The smallest sensor signal corresponds to the diffuse radiation, the greatest to the global radiation. If photodiodes are used as the light- sensitive sensors, the instrument can be produced particularly cost-effectively. <IMAGE>
Patent AT-410198-B (AT)
Title: Securing device for hydraulically operated side walls of goods vehicle load platform
IPC: B60P1/44
Filed: 1995-12-01
Granted: 2003-02-25
Abstract: The device has a transverse carrier for the side walls attached to the rear of the vehicle frame with bearing flanges symmetrically placed wrt. the longitudinal central axis with through holes for bearing bolts of side wall lifting and pivoting elements. The transverse carrier is an essentially rectangular cross-section aluminium hollow box extrusion (1). The carrier has upper and lower grooves (3',3'') for shape and force-locking latching of the ends of bearing flange bracket arms (4'',4''') for the lifting and pivoting elements. The bearing flanges are formed from sections of extruded aluminium profile. Bearing flanges on the ends of the side walls have cylindrical through holes (5'',5''') for the bearing bolts and are welded to the load platform.
Patent AT-403700-B (AT)
Title: Gripper head for a thread, in particular for a seam weaving machine
IPC: D03D41/00
Filed: 1996-11-22
Granted: 1998-04-27
Abstract: What is described is a gripper head for a thread 4, in particular for a seam weaving machine, with two gripping jaws 2, 3 movable relative to one another and gripping the thread 4 between them and with a sensor 13 monitoring the bearing of the gripping jaws 2, 3 one on the other and located in the region of the bearing face 12 of one gripping jaw 2. In order to provide advantageous design conditions, it is proposed that the sensor 13 consist of a compressed-air line 14 opening out in the bearing face 12 of the associated gripping jaw 2 and of a measurement transducer 15 for the pressure or the flow in the compressed-air line 14. <IMAGE>
Patent AT-388967-B (AT)
Title: Climbing element with mounts
IPC: E06C9/04
Filed: 1983-06-28
Granted: 1989-09-25
Abstract: Climbing elements, of which the free ends 1 are of tubular design and are enclosed by dowel-like mounts 3 which are profiled on the outside, are anchored in bores of the masonrywork. The task has been to develop a climbing element, with a mount, which, once fastened in the wall of the structure, cannot be removed without the mount being destroyed and which is protected, in particular, against the action of corrosive liquids or gases. This is achieved in that the mounts 3 are positioned in a force-fitting manner on the ends 1 of the climbing element. The climbing element is preferably enclosed by a plastic casing 2 in its tread region, the mounts 3 being welded in a liquid-tight manner to the end region of the plastic casing 2. The climbing element according to the invention is firmly connected to the mount and reliably protected against corrosion. It is no longer possible for it to be drawn out of the masonrywork. <IMAGE>
Patent AT-389446-B (AT)
Title: Use of an 8-chlorobenzothiazepine for the production of a medicament
Inventor: TAKASHIMA KOHKI
IPC: A61K31/55
Filed: 1987-10-08
Granted: 1989-12-11
Abstract: The invention relates to the use of cis-2-(4- methoxyphenyl)-3-acetoxy-5-(2-(dimethylamino)ethyl)-8- chloro-2,3-dihydro-1,5-benzothiazepin-4(5H)-one or of a pharmaceutically acceptable acid addition salt thereof for producing a pharmaceutical composition for improving the composition of lipids in the blood. The improvement consists in increasing the ratio of the amount of HDL-cholesterol to the amount of total cholesterol.
Patent AT-399996-B (AT)
Title: Device for dealing with hot cooking utensils
Inventor: TARSETTI MARGIT
IPC: A47J45/10
Filed: 1988-12-22
Granted: 1995-08-25
Abstract: The invention relates to a device for dealing with hot cooking utensils during cooking on the cooker and with a hot roasting pan in the oven. It comprises two rods 1 and 2, which are connected at one end by means of a spreading spring 3 and at the other end each have two-part gripping claws 5 and 6. The rear part of each gripping claw is longer than the front part. <IMAGE>
Patent CH-633406-B (CH)
Inventor: BOLZT JEAN
IPC: G04C10/00
Filed: 1979-06-29
Abstract: The wheel work (15) of the movement is situated on a face of the plate (1) whereas all the other elements of the watch, with the exception of a bar (11) supporting one of the bearings of the rotor (5) of the motor, are situated on the other face (9) of the said plate. All of these superimposed elements are constituted by the stator (13-14) of the motor, a bridge (8) and the thin, flexible substrate (16) of the electronic module. <IMAGE>
Patent DK-165358-B (DK)
Inventor: NOVOTNY PAVEL
IPC: A61P31/04
Filed: 1985-05-10
Abstract: The present invention provides novel antigenic preparations comprising proteinaceous material associated with adenylate cyclase activity in cultures of B.pertussis, the said preparations being useful as components of acellular whooping cough vaccines. The invention further provides methods for the isolation of such antigenic preparations.
Patent DK-164118-B (DK)
Inventor: BAGINSKI RICHARD MARK
IPC: C11D3/20
Filed: 1986-07-30
Abstract: Granular detergent compositions having an effective suds controlling agent comprising a suds-controlling silicone material which is substantially removed from contact with the surfactant component or alkaline component of the composition by incorporation in, e.g., a polyethylene glycol carrier, with preferably a small amount of fatty acid, in an irregularly shaped particle having a minimum dimension of at least about 0.05 cm. and being substantially free of water soluble inorganic salts.
Patent DK-156421-B (DK)
Inventor: MEYER RAYMOND JOSEPH
IPC: B62D33/06
Filed: 1982-08-31
Abstract: A hinged hatch assembly for the roof of a vehicle cab having an opening formed therein. The assembly includes a hatch which completely covers the opening when in a closed position. The hatch is connected to the roof of the vehicle cab by a pair of support arms. Each support arm contains a first and a second forked end whereby the first forked ends are pivotally attached by brackets to one side of the roof opening and the second forked ends are pivotally attached by brackets to the underside of the hatch. Sandwiched on each side of the brackets between the forked ends of the support arms are frictional elements which are spring loaded to impart a predetermined frictional force on the members. The frictional contact permits the hatch to be opened at various angles and at various positions relative to the plane of the roof and to remain in the desired position irrespective of any vibration or motion imparted into the vehicle. The hinged hatch roof assembly is capable of providing ventilation as well as serving as an escape route from the interior of the vehicle cab.
Patent DK-153021-B (DK)
Inventor: WEBB JOHN THOMAS HIRD
IPC: B66D3/06
Filed: 1984-12-21
Abstract: A winch comprises a capstan (2) provided with a plurality of circumferential grooves (11). The grooves (11) comprise a high friction material and the density of the material of each groove (11) is different, so that the coefficient of friction of the cable bearing surface increases from the load end to the tail end of the capstan (2).
Patent FI-66608-B (FI)
Inventor: WEBER KARL-HEINZ
IPC: C07D335/02
Filed: 1980-12-19
Granted: 1984-07-31
Abstract: Compounds of the steroisomeric formulas   <IMAGE>  and  <IMAGE> wherein R1 and R2, which may be identical to or different from each other, are each phenyl, substituted phenyl, thienyl or furyl; R3 is hydrogen or straight or branched alkyl of 1 to 3 carbon atoms; and R4 is straight or branched alkyl of 1 to 3 carbon atoms; or R3 and R4, together with each other and the nitrogen atom to which they are attached, form a piperidino, 4-amino-piperidino, 4-(lower alkylamino)-piperidino, piperazino, 4-(alkyl of 1 to 2 carbon atoms)-piperazino or morpholino radical; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as antidepressants.
Patent FI-79243-B (FI)
Inventor: WITTWER FRITZ
IPC: A23J3/00
Filed: 1983-03-24
Granted: 1989-08-31
Abstract: An apparatus and method to produce capsules of a moldable hydrophilic polymer composition, preferably gelatin, using a combination of an injection molding device with a microprocessor (28) to precisely control the conditions of time, temperature, pressure and water content of the hydrophilic polymer composition, in a cyclic molding process, are disclosed. The injection molding device comprises a hopper unit (5) for feeding gelatin to an injection unit (1) from which plasticised gelatin is injected into a molding unit (2).
Patent FI-94133-B (FI)
Inventor: KANEKO MASAKATSU
IPC: C07D233/54
Filed: 1986-04-18
Granted: 1995-04-13
Abstract: New griseolic acid derivatives have various groups attached to the sugar part in place of the adenine group of griseolic acid itself. These groups are all purine derivatives or ring-opened purine analogs. The compounds are useful as inhibitors of phosphodiesterases. They may be prepared by replacing the adenine moiety of griseolic acid and/or dihydrodesoxygriseolic acid and/or by replacing other substituent groups.
Patent FI-82048-B (FI)
Inventor: SCHOEN UWE
IPC: C07D471/10
Filed: 1986-08-01
Granted: 1990-09-28
Abstract: Tetraoxo compounds of the Formula (I)    <IMAGE>  (I)  wherein R1 is an alkyl, alkenyl, phenylalkyl or cycloalkylalkyl group, R2 and R3 are each independently an alkyl or phenyl group or together denote an alkylene group, W is a (CH2)n-Q group, in which n is 2 to 10 and Q is (a) a displaceable leaving group X, or (b) Z-R4, where Z is a 1-piperazinyl group, and R4 is in position 4, and is hydrogen or a phenyl, substituted phenyl, N-heteroaryl or substituted N-heteroaryl group; and salts and acid addition salts of said compound, and a method for their preparation. Selected compounds of Formula (I) have been found to have central nervous system affecting activity.