baber/WOPTO huggingface dataset:
Patent EP-1594854-B1 (EP)
Inventor: HYNES JOHN
IPC: C07D417/02
Filed: 2004-02-06
Granted: 2010-09-01
Abstract: The present invention provides thiazolyl-based compounds of formula (I), useful for treating p38 kinase-associated conditions, wherein ring A is phenyl or pyridyl, and X, Y, B, R<SUP>2</SUP>, R<SUP>3</SUP>, Z<SUP>1 </SUP>m and n are as defined herein. The invention further pertains to pharmaceutical compositions containing at least one compound according to the invention useful for treating p38 kinase-associated conditions, and methods of inhibiting the activity of p38 kinase in a mammal.
Patent EP-1601587-B1 (EP)
Inventor: LANCESSEUR DIDIER
IPC: B65D43/16
Filed: 2004-03-03
Granted: 2006-06-14
Abstract: A device for dispensing oblong objects comprising: (i) a main dispensing opening for allowing the objects to be dispensed to pass therethrough one by one; (ii) at least one other opening of elongate shape, one of whose sides opens into the main dispensing opening, the elongate opening having an opening width equal to or greater than a minimum thickness of the object to be dispensed; and (iii) guide surfaces for guiding the objects to be dispensed. The guide surfaces lie along front sides of the elongate opening and face the objects to be dispensed, so as to collect and guide the objects toward at least one of the elongate openings.
Patent EP-1640716-B1 (EP)
Inventor: TANAKA YOSHIYUKI
IPC: C12N5/00
Filed: 2004-03-09
Granted: 2011-03-02
Abstract: A blood cell separation membrane capable of separating blood cells from serum and plasma while preventing blood cell hemolysis. Such a blood cell separation membrane can be obtained by impregnating a porous membrane capable of separating cells from fed blood with a solution containing a hydrophobic aminocarboxylic acid, a protein derived from silk, Tris, TES, ϵ-aminohexanoic acid, tranexamic acid or heparin and drying the impregnated membrane.
Patent EP-1606293-B1 (EP)
Inventor: BERGHAUSEN JOERG
IPC: A61K31/04
Filed: 2004-03-15
Granted: 2009-08-19
Abstract: The present invention relates to cephalosporin of formula (I) in crystalline form. The compound of formula (I) in crystalline form is useful as antibiotics having potent and broad antibacterial activity; especially against methicillin resistant Staphylococci (MRSA) and Pseudomonas aeruginosa.
Patent EP-1608311-B1 (EP)
Inventor: GRIND MARGARETHA
IPC: A61K31/397
Filed: 2004-03-19
Granted: 2010-07-28
Abstract: According to the invention there is provided a cholesterol lowering therapy method and a method for modification of lipid (triglyceride), lipoprotein, and apolipoprotein profiles associated with an increased risk of cardiovascular complications comprising the administration of a low molecular weight thrombin inhibitor, or a pharmaceutically acceptable derivative thereof, to a patient in need thereof.
Patent EP-1633541-B1 (EP)
Inventor: HOFMANN MICHAEL
IPC: B27N3/00
Filed: 2004-06-03
Granted: 2012-05-30
Abstract: The invention relates to a board consisting of a derived timber product, wherein wood chips or fibres and plastic particles or fibres are compressed with a binding agent according to a hot-pressing method in order to form a board. Some of the wood chips or fibres are substituted by a ground or defibrated agglomerate of mixed plastics from the waste disposal, and the particle size of wood chips or fibres and ground agglomerate is approximately the same.
Patent EP-1711972-B1 (EP)
Inventor: MELOSI MARIO
IPC: C25B1/12
Filed: 2004-06-23
Granted: 2010-02-10
Abstract: Electrochemical cells modules made up of couples of catalytic multilayer porous electrodes forming the anodes and the cathodes and delimitating external gaseous areas and internal areas containing the electrolyte wherein the pressure modulators, generating two pressure cycles independently synchronized but of opposite phase, act at the inlet and at the outlet of the electrolyte and the multilayer porous electrodes are weeping on the gas side. According to a preferred embodiment the multilayer porous electrodes are hydrophobic and conductive on the gas side, the conductive and catalytic middle layers are hydrophobic and hydrophilic, the non-conductive and non-catalytic layer on the electrolyte side is hydrophilic.
Patent EP-1725476-B1 (EP)
Inventor: REGAN PHIL
IPC: F16K17/06
Filed: 2004-08-05
Granted: 2007-10-31
Abstract: The invention is a pressurized gas providing and gas pressure regulating device. The invention is a container with an over pressurized second chamber of pressurized gas that can be released to the exterior of the container when a valve that is integrally connected to a piston that along with a first cylinder forms a first chamber that is filled with a comparably less over pressurized gas that pushes the valve open when the gas pressure outside of the container is too low, thereby permitting the over pressurized second chamber to fluidly connect via the valve and thereby increase the pressure outside the container, such as to a volume of gas located below a piston within a fluid dispenser, the first and second chambers are shaped as cylinders and the first cylinder fits within the second chamber.
Patent EP-1668397-B1 (EP)
Inventor: WILLEMSEN OSCAR H
IPC: G02B26/08
Filed: 2004-07-07
Granted: 2007-05-02
Abstract: A two dimensional scanning device, for use in a projecting display, comprising a surface ( 53 ) suspended by at least two torsion elements ( 55 ) defining a torsion axis (B), and a first actuator ( 60, 61 ) for pivoting said surface ( 53 ) around said torsion axis (B). The scanner further comprises a cantilever beam ( 51 ) having one end fixed in relation to said surface and an opposite end arranged to bend around a bending axis (A) non-parallel to said torsion axis (B). The cantilever beam ( 51 ) is provided with a reflective surface and a second actuator ( 58 ) is arranged to bring said cantilever beam to oscillate at its resonance frequency. The combination of a slow torsion scanner and a faster cantilever scanner 10 provides a two dimensional scanner capable of scanning a laser beam in a raster pattern to project an image.
Patent EP-1635079-B1 (EP)
Inventor: OKADA KOICHI
IPC: F16C19/18
Filed: 2004-06-01
Granted: 2012-05-02
Abstract: According to the present invention, there is provided a bearing apparatus for a wheel of vehicle comprising a hub wheel integrally formed therewith a wheel mounting flange on the periphery at one end thereof, and a double row rolling bearing, the double row rolling bearing comprising an outer member integrally formed therewith a body mounting flange on the periphery thereof and also formed therewith double row outer raceway surfaces, an inner member including said hub wheel and formed therewith double row inner raceway surfaces each arranged opposite to each of said double row outer surfaces, and double row rolling elements freely rotatably contained between said double row outer and second raceway surfaces, said double row rolling bearing being adapted to be applied a predetermined preload  characterized in that : there are arranged a separate outer or inner ring on at least one of said outer and inner members, and a preload varying means arranged at an abutting portion between said outer and inner members for varying the preload applied to the bearing, said preload varying means can be extended or contracted based on an output signal from a detecting sensor for detecting the running condition of vehicle.
Patent EP-1622485-B1 (EP)
Inventor: BOOKER TODD
IPC: A47B88/00
Filed: 2004-05-13
Granted: 2011-10-05
Abstract: A system for releasably securing a drawer to a drawer slide includes a drawer slide, a catch insert for receiving and securing a portion of a locking lever, a drawer, a locking lever comprising at least one tooth, pivotably mounted to the drawer and a spring for releasably engaging the at least one tooth in contact with the catch insert. The catch insert can be mounted in the aperture provided in the drawer slide and can include a plurality of ridges and grooves aligned in a direction parallel to the sliding direction of the drawer, and can extend in a direction perpendicular to the sliding direction of the drawer. The locking lever can include a plurality of teeth, which are aligned in a direction parallel to the sliding direction of the drawer, and can extend in a direction perpendicular to the sliding direction of the drawer.
Patent EP-1638526-B1 (EP)
Inventor: EDELMAN ELAZER R
IPC: A61K31/675
Filed: 2004-06-24
Granted: 2010-04-28
Abstract: A method of treating an acute myocardial infarction by administering to an individual an effective amount of a formulation which inhibits and/or depletes phagocytic cells with high specificity, thereby suppressing the inflammatory response that occurs during and following acute myocardial infarction. The formulation comprises an agent which is an intracellular inhibitor that is released within the targeted phagocytic cells, specifically macrophage/monocytes, and inhibits and/or destroys the macrophages and/or monocytes, thereby reducing the final zone of infarct and improving cardiac repair and myocardial remodeling. Since macrophages and monocytes possess the unique ability to phagocytose large bodies, the agent is formulated into a specific size such that it can enter cells primarily via phagocytosis.; Thus, the specifically sized formulation selectively targets monocytes/macrophages. The formulation may comprise an encapsulated agent, an embedded agent or a particulate agent, wherein the formulation is of a specific size, such that it can enter cells primarily via phagocytosis. The formulation is preferably in the size range of 0.03-1.0 microns.
Patent EP-1651484-B1 (EP)
Inventor: ULLRICH THORSTEN
IPC: B60T8/40
Filed: 2004-07-08
Granted: 2008-12-03
Abstract: L'invention concerne un procédé visant à éliminer le risque de blessure (risque de pincement) de la personne qui effectue, sur un système de freinage équipé d'un accumulateur haute pression, des travaux de maintenance à l'arrêt sans actionnement de la pédale, une montée en pression étant simultanément active. Le procédé selon l'invention comprend les étapes suivantes : désactivation d'une régulation électronique affectée au chargement de l'accumulateur haute pression et exécutée par une unité de contrôle-commande (16) ; fermeture d'une soupape de séparation (11) affectée à un essieu du véhicule ; ouverture des soupapes d'alimentation (17, 18) affectées à l'essieu de véhicule afin de déplacer le moyen de pression dans les freins de roues (7, 8) de l'essieu du véhicule et détermination simultanée de valeurs (p, ΔV) représentant la pression hydraulique injectée dans les freins de roues (7, 8) ainsi que le déplacement du moyen de pression ; enfin, évaluation des valeurs pour juger de l'état des freins (7, 8) des roues.
Patent EP-1673732-B1 (EP)
Inventor: HOLDEN CARREN M E
IPC: G06Q10/00
Filed: 2004-10-07
Granted: 2009-05-13
Abstract: A method is provided for transforming data from a high-dimensional to low-dimensional design space, and for inspecting the transformed data in such a manner as to permit effective navigation and exploration of the high-dimensional design space. Conveniently, an optimum/conditional value for a prescribed functional representation of the transformed data can be derived by visual inspection of a 2-D image map representation of the transformed data. Significantly, the invention has utility for various aircraft design applications and although this technology has been developed with reference to aircraft aerodynamic design in particular, the design space visualisation and curve-fitting technology developed is general. It should therefore be equally applicable to other disciplines such as cost analysis, structures and computational electromagnetics, in which expensive analysis tools are used to find optima for complicated design problems. It is expected to be particularly useful in multi-disciplinary design and situations where there are multiple optima in the design space.
Patent EP-1795399-B1 (EP)
Inventor: NAKAO MAKOTO
IPC: B60R13/04
Filed: 2004-10-01
Granted: 2011-09-28
Abstract: モール本体に取り付けた状態において、隙間を生じ難くすることができ、かつ優れた意匠性を発揮することができるモールエンドキャップである。引掛部１０は、前面１００ａと後面１００ｂとが互いに向い合いながら傾斜面となり、側面１００ｃが台形形状である四角柱の第１段部１００と、第１段部１００の上段に位置し、前面１０１ａが傾斜面となり、後面１０１ｂが垂直面となり、側面１０１ｃが台形形状である四角柱の第２段部１０１とを備えている。
Patent EP-1685302-B1 (EP)
Inventor: BJOERKLUND ANDERS
IPC: E04G3/00
Filed: 2004-10-06
Granted: 2010-02-24
Abstract: An adjustable height platform (10) is suspended on cables (13) from the vessel roof (6) and comprises at least two parallel and spaced apart beams (11) which are arranged side by side and have a compartmentalised cross- section. The height of each beam can be altered individually. The beams are suspended from the cables and connected via at least one truss (12) extending at right angles to the beams and resting on top of them. The top sides of the beams are flat so that they form a floor (18) on which one can walk and work on safely. The trusses can also be walked and worked on safely and have an overlength which enables them to move the beams in the height and sideways direction.
Patent EP-1673259-B1 (EP)
Inventor: BRADBURN ALAN
IPC: B60R21/239
Filed: 2004-10-14
Granted: 2012-02-01
Abstract: An inflatable air-bag (1) is disclosed which defines an inflatable chamber (3). The air-bag comprises an inner elastic membrane (5) provided in the peripheral wall of the air-bag, there being a vent-hole (7) formed through the elastic membrane (5). An outer membrane (8) is provided on the outside of the air-bag which extends across at least part of the inner membrane (5) and the vent-hole (7). The outer membrane defines a pucker (10) over the inner membrane and the vent-hole (7). The pucker (10) is open so as to define an outlet flow path from the vent-hole (7) when the inner membrane (5) is spaced from the pucker (10). The inner membrane (5) is configured to stretch and seal against the pucker (10) around the vent-hole (7) when the internal pressure within the inflatable chamber (3) exceeds a predetermined value.
Patent EP-1629003-B1 (EP)
Inventor: KABAT DAVID
IPC: C12Q1/70
Filed: 2004-05-03
Granted: 2008-03-12
Abstract: Vif binds to APOBEC3G and induces its rapid degradation, thus eliminating it from cells and preventing its incorporation into HIV-1 virions. Vif contains two domains, one that binds APOBEC3G and another with a conserved SLQ(Y/F)LA motif that mediates APOBEC3G degradation by a proteasome-dependent pathway. Provided herein are methods of exploiting these discoveries to develop compounds useful to inhibit Vif degradation of APOBEC3G, and thereby inhibit viral infection and/or replication.
Patent EP-1670308-B1 (EP)
Inventor: HEYER JOERG
IPC: C07K14/47
Filed: 2004-08-27
Granted: 2012-06-27
Abstract: Chimeric nonhuman mammals useful as inducible spontaneous cancer models are disclosed. The nonhuman mammals are obtained by introducing one or more genetically modified embryonic stem (ES) cells into an early stage embryo, and then implanting the manipulated embryo into a surrogate mother. The ES cells contain a recombinant oncogene, and also may contain a genetic mutation that deletes or inactivates a tumor suppressor gene. Models of different types of cancer are produced by introducing different combinations of genetic mutations into the ES cells that are introduced into the early stage embryo.
Patent EP-1669389-B1 (EP)
Inventor: YOKOTSUKA SHUNSUKE
IPC: C08L71/10
Filed: 2004-09-29
Granted: 2009-08-26
Abstract: To provide a crosslinkable fluorinated aromatic prepolymer which is capable of forming a cured product having a low relative permittivity, high heat resistance, low birefringence and high flexibility, and its uses.  A crosslinkable fluorinated aromatic prepolymer which is obtained by subjecting a compound (Y-1) having a crosslinkable functional group (A) and a phenolic hydroxyl group and/or a compound (Y-2) having a crosslinkable functional group (A) and a fluorinated aromatic ring, to a condensation reaction in the presence of a HF-removing agent, with a fluorinated aromatic compound (B) represented by the formula (1):   
(wherein n is an integer of from 0 to 2, each of a and b which are independent of each other, is an integer of 0 to 3, and each of Rf 1  and Rf 2  represents a fluorinated alkyl group having at most 8 carbon atoms and a compound (C) having at least 3 phenolic hydroxyl groups, and which has crosslinkable functional groups (A) and ether bonds and has a number average molecular weight of from 1×10 3  to 5×10 5 .
Patent EP-1688293-B1 (EP)
Inventor: KUROIWA YASUYUKI
IPC: F16D41/069
Filed: 2004-10-07
Granted: 2009-04-15
Abstract: 自動二輪車は、クランク軸を有する内燃機関と、変速機構と、遠心式発進クラッチと、トルクコンバータとを備えている。遠心式発進クラッチとトルクコンバータは、クランク軸および変速機構の間に設けられている。クランク軸とトルクコンバータの間に内燃機関の駆動力よりも車輪から変速機構側に伝達される駆動力が大きく、かつ、クランク軸の回転速度が所定値以上である時のみ、変速機構からクランク軸へ動力を伝達する一方向クラッチが設けられている。
Patent EP-1797283-B1 (EP)
Inventor: RENAUD PHILIPPE
IPC: F01D5/14
Filed: 2004-11-16
Granted: 2013-12-18
Abstract: There is provided a turbocharger with a variable nozzle assembly having a plurality of cambered vanes positioned annularly around a turbine wheel, each vane (20) being pivotable around a pivot point (Pp) and being configured to have a leading edge (Ple) and a trailing edge (Pte) connected by an outer airfoil surface (2) and an inner airfoil surface (4), said outer airfoil surface (2) being substantially convex and said inner airfoil surface (4) having a convex section at the leading edge (Ple) which has a local extreme (Pex) of curvature and transitions into a concave section towards the trailing edge (Pte). The positions of the pivot point (Pp) and the local extreme (Pex) are set such that, even when the vanes are placed in a closed position, the exhaust gas stream exercises a positive torque on the vanes which tends to open the nozzle.
Patent EP-1747602-B1 (EP)
Inventor: EDWARD BRIAN J
IPC: H01Q5/42
Filed: 2004-07-23
Granted: 2009-03-04
Abstract: A line-replaceable unit (200) for a phased array antenna including a thermally conductive housing (201) having a front face (202) and an opposed rear face (203), at least one open-ended waveguide (204) extending through the housing from the front face (202) to the rear face (203), at least one first radiating element (239) including the waveguide (204) and adapted to emit energy in a first frequency band; and at least one second radiating element (205) positioned on the front face (202) of the housing and adapted to emit energy in a second frequency band distinct from the first frequency band. The waveguide (204) is dimensioned to pass energy in the first frequency band and is exposed to the environment outside the housing at the front (202) and rear (203) faces to define a cooling duct passing through the housing.
Patent EP-1684818-B1 (EP)
Inventor: TANG YIWEN
IPC: A61L27/34
Filed: 2004-11-19
Granted: 2011-12-21
Abstract: A medical article comprising an implantable substrate having a coating is disclosed, the coating comprising a biologically erodable polymer having the glass transition temperature below about −50° C. The biologically erodable polymer can be blended with a polymeric additive which either has the glass transition temperature of about −50° C. or higher, or a degree of crystallinity greater than that of the first polymer.
Patent EP-1576976-B1 (EP)
Inventor: HIEJIMA KATSUHIRO
IPC: A61M5/14
Filed: 2005-03-11
Granted: 2008-12-10
Abstract: A patient-controlled analgesia (PCA) apparatus capable of additional administration simultaneously with continuous injection is provided, in which a drug solution can be administered additionally via a release valve (4,6) while being injected continuously in a slight amount via a flow rate control tube. The period of drug solution injection can be controlled by changing the length of the flow rate control tube, the amount of administration can be selected as desired by changing the size of a sub-reservoir (7), the line is simple, operation is easy, defects such as leakage are prevented, and manufacturing cost is low.
Patent EP-1596351-B1 (EP)
IPC: G06F17/21
Filed: 2005-04-30
Granted: 2010-10-13
Abstract: The method involves storing in the memory of a data processing device the text constituents in different languages. A preselection process defines which language will be used for the marking. The data processing device selects the corresponding text constituents in the preselected language from the memory that correspond to each text constituent of an input data set. The marking letters are assembled with the selected text constituents to form an output data set.
Patent EP-1602432-B1 (EP)
Inventor: BATELAAN DIRK CORNELIS
IPC: B23H7/10
Filed: 2005-05-06
Granted: 2011-09-21
Abstract: The present invention relates to a flexible electrical connection member (16) for conveying current from the machining generator to the machining contact support (17) of a wire electrical discharge machine comprising a function of threading/re-threading the electrode wire automatically, characterized in that it is made up of a single piece made from a material that is a good conductor of electricity and in that the body of the said piece has two series of lateral notches (15) on each side of its main axis and intended to give it good elasticity and allow it to flex repeatedly. <IMAGE> <IMAGE> <IMAGE>
Patent EP-1762877-B1 (EP)
Inventor: AERTSEN ADRIANUS
IPC: G02B21/00
Filed: 2005-09-13
Granted: 2010-11-17
Abstract: Device has digital micro-mirror equipment (2), on which the radiation is reflected before it incidents on the sample (1). The digital micro-mirror equipment is arranged in the optical path. The part of the radiation, which incidents on the micro-mirror, irradiates a position of the sample or misses this position depending upon the switching condition of each individual micro-mirror of the digital micro-mirror equipment. Independent claims are also included for the following: (1) Irradiation method; and (2) Application of a digital micro-mirror equipment.
Patent EP-1659124-B1 (EP)
Inventor: KIMURA KEIZO
IPC: C07D487/04
Filed: 2005-09-27
Granted: 2008-11-12
Abstract: Disclosed is a pyrrolotriazole compound represented by the following formula (I) and having an organic compound incorporated into crystals thereof:   
wherein Org represents an organic compound having at least one carbon atom; and n 15  denotes a positive number.
Patent EP-1676954-B1 (EP)
Inventor: SCHWONKE PAUL A
IPC: D21D5/02
Filed: 2005-12-22
Granted: 2008-01-16
Abstract: A process is described for manufacturing a paperboard from a high consistency slurry containing high levels of crosslinked cellulosic fibers by dispersing the fibers in a screen with a rotor in the screen and then passing the fibers through the screen basket with a hole diameter of at least 2 mm and forming the cellulosic fibers on a foraminous support. Another slurry of regular cellulosic fibers is deposited on at least one side of the first slurry during the formation process. The formed web is dewatered and dried.
Patent EP-1677017-B1 (EP)
Inventor: LINGLET STEPHANE
IPC: B29C49/36
Filed: 2005-12-06
Granted: 2008-02-13
Abstract: The cooling system for a positioning crown gear comprising two rings (4, 7) that can rotate relative to one another and are equipped with rolling tracks and bearings (8) consists of at least one coolant fluid circuit in contact with one of the rings. The system also incorporates a crown gear temperature monitor (19) and a coolant fluid flow regulator to adjust the temperature according to a set reference value. The coolant fluid circuit is basically annular in shape and is made up of curved conduit sections (10a - 10d) fitted against one of the crown gear rings (7). At least one of the conduit sections is equipped with cooling fluid (water) feed and return couplings.