baber/WOPTO huggingface dataset:
Patent IL-132348-A0 (IL)
Title: Gene directed antibody-enzyme prodrug therapy
IPC: C12R1/91
Filed: 1998-05-05
Abstract: The invention provides a gene construct encoding a cell targeting moiety and a heterologous prodrug activating enzyme for use as a medicament in a mammalian host wherein the gene construct is capable of expressing the cell targeting moiety and enzyme as a conjugate within a target cell in the mammalian host and wherein the conjugate is directed to leave the cell thereafter for selective localisation at a cell surface antigen recognised by the cell targeting moiety.
Patent IL-140093-A0 (IL)
Title: Glycopeptide derivatives and pharmaceutical compositions containing the same
IPC: C07K7/06
Filed: 1999-12-22
Abstract: Disclosed are derivatives of glycopeptide compounds having at least one substituent of the formula: —Ra—Y—Rb—(Z)x where Ra, Rb, Y, Z and x are as defined, and pharmaceutical compositions containing such glycopeptide derivatives. The disclosed glycopeptide derivatives are useful as antibacterial agents.
Patent IL-149576-A0 (IL)
Title: New process
IPC: C07C67/08
Filed: 2000-11-29
Abstract: The present invention relates to novel resolution methods, which are useful in the preparation of enantiomerically enriched intermediates which in their turn are useful in the prepartion of compounds with a pharmacological effect on the insulin resistance syndrome (IRS). It is such a process that the present inventions sets out to define, and more particularly for the preparation of the (S)-enantioner of certain 2-ethoxy-3-(4-hydroxyphenyl)propanoic acids and derivatives thereof.
Patent IL-150021-A0 (IL)
Title: Ferrule with relief to reduce galling
IPC: F16L19/10
Filed: 2000-12-20
Abstract: High localized loading, galling, and high torque forces have been generally eliminated or greatly reduced in a two ferrule tube fitting assembly through suitable modification of the rear ferrule so as to redirect the reaction forces acting between the front ferrule and the drive nut. The rear ferrule has a cylindrical interior wall that closely surrounds the tube end and is provided on the interior cylindrical wall with a circumferentially continuous radial recess that is located between the nose and rear wall of the rear ferrule. The rear ferrule also has a radially external wall that is substantially conical and additionally shaped to extend radially outward toward the enlarged diameter portion or flange of the rear ferrule. The rear ferrule further includes a contoured face on the rear driven surface of the ferrule that engages the drive surface of the drive nut.
Patent IL-154655-A0 (IL)
Title: Clamping apparatus with a clamping chuck and a work piece carrier releasably connectable thereto
IPC: B23Q3/02
Filed: 2003-02-27
Abstract: The apparatus has a clamping chuck (1) has a central opening (2) for receiving a clamping pin (11) which clamps a workpiece carrier (10), and gas outlet openings (6) located in conical inserting portion (3) of central opening for blowing a gaseous medium against exposed surface portions (12,12a) of clamping pin to clean the surfaces upon inserting clamping pin into central opening of clamping chuck.  The workpiece carrier is releasably connected to the clamping chuck. The workpiece carrier has a flat bottom surface (10a) and comprising the clamping pin protruding from the flat bottom surface. The clamping chuck comprises a clamping mechanism for fixing the clamping pin of the workpiece carrier in the central opening. The clamping pin has a rear section adjacent to the flat bottom surface of the workpiece carrier. The exposed surface portions of the clamping pin engages the conical inserting portion of the central opening for aligning the position of the clamping pin in X or Y directions.
Patent IL-155314-A0 (IL)
Title: Hydrophilic coatings for medical implements
IPC: A61L29/08
Filed: 2003-04-09
Abstract: Compositions, methods, devices and kits utilizing water-based hydrophilic coating formulations on medical implements. The composition for applying a coating comprises a sulfonated polyester, water, and a surface active agent. Methods for coating a medical implement comprise providing an aqueous dispersion comprising sulfonated polyester and surface active agent, contacting the medical implement with the aqueous dispersion, and drying the medical implement.
Patent IL-175551-A0 (IL)
Title: Cancellation of pilot and unwanted traffic signals in a cdma system
IPC: H04B1/10
Filed: 2006-05-10
Abstract: An apparatus for code division multiple access (CDMA) wireless communication comprising a receiver configured to receive a CDMA signal that includes a desired traffic signal and a second signal, the desired traffic signal being spread with a desired traffic spreading code and the second signal being spread with a second spreading code; means for generating a second signal cancellation component including means for generating a second signal strength by despreading the CDMA signal based on the second spreading code; means for generating a second signal cancellation factor by selectively combining the second signal spreading code and the desired traffic spreading code; and means for combining the second signal strength and the second signal cancellation factor to generate the second signal cancellation component; means for generating a despread desired traffic signal by despreading the CDMA signal based on the desired traffic spreading code; and means for combining the despread desired traffic signal and the second signal cancellation component to cancel second signal noise from the despread desired traffic signal.
Patent IL-187506-A0 (IL)
Title: Container with hollow needle
IPC: B67D7/74
Filed: 2007-11-20
Abstract: The container (1) has an envelope (6) that is closed up to an opening (7) for delivering the medicine, an arrangement for connecting (4) the opening to an administration device, whereby the container is designed so that the medicine is delivered by varying at least one region of the envelope, which is made in one piece. Independent claims are also included for the following: (A) a method of manufacturing an inventive device (B) and a device for administering a medicine.
Patent IL-192180-A0 (IL)
Title: Use of c1 inhibitor for the prevention of ischemia-reperfusion injury
Filed: 2008-06-15
Abstract: The present invention relates to the therapeutic and prophylactic use of Cl inhibitor for preventing, reducing and treating ischemia and reperfusion injury. The Cl inhibitor of the present invention is still therapeutically effective when administered after an ischemic period and reperfusion and therefore particularly useful for unforeseen occurrences of ischemic reperfusion such as e.g. a stroke.
Patent IL-195537-A0 (IL)
Title: Synchronization of timing advance and deviation
IPC: H04W56/00
Filed: 2008-11-26
Abstract: A mobile terminal and method for reducing the latency from timing deviation (TD) measurement to time advance (TA) adjustment. The invention uses a deterministic procedure to coordinate time advance (TA) commands and timing deviation (TD) measurements so that failed transmissions or mobile terminals signal propagation changes can be recognized and corrected much more rapidly. Radio resource efficiency is maximized by minimizing signaling overhead through effectively reducing the frequency of time advance commands. This is accomplished by using TA commands signals which include a Connect Frame Number (CFN) to specify particular radio frames for time advance (TA) adjustment. The potential for timing deviation (TD) measurements to be incorrectly processed in conjunction with adjusting a physical reception window and calculating mobile termination location is minimized, without excessive command signaling requirements. <IMAGE>
Patent IL-207126-A0 (IL)
Title: Method and related compositions for reduction of fat
IPC: A61K31/575
Filed: 2010-07-21
Abstract: Compositions and methods useful in the reduction of localized fat deposits in patients in need thereof using pharmacologically active detergents are disclosed. The pharmacologically active detergent compositions can additionally include antiinflammatory agents, analgesics, dispersion or anti-dispersion agents and pharmaceutically acceptable excipients. The pharmacologically active detergent compositions are useful for treating localized accumulations of fat including, for example, lower eyelid fat herniation, lipodystrophy grid fat deposits associated with cellulite and do not require surgical procedures such as liposuction.
Patent RO-126701-A0 (RO)
Title: Apparatus and method for acquiring the skills required in the activity of stimulating the growth of a new-born baby or infant
Inventor: SULTANA GEORGETA
IPC: A61B5/053
Filed: 2011-03-14
Abstract: The invention relates to an apparatus and a method for a person to acquire the skills to be employed in stimulating the harmonious growth of a new-born baby or infant. According to the invention, the apparatus consists of a testing module (A) preferably having the shape and size of a baby or infant which, in each of some main interest zones (a, b, c, d and e), namely the femur, abdomen, breast, forearm and back, has one of some strain gauges (8, 9, 10, 11 and 12) oriented along the longitudinal muscle development axis, intended to take over the mechanical strain and convert it into easy measurable electric signal which is sent, by means of a connection cable (B), to a programming, measuring and controlling module (C) wherefrom the electric values are sent, by means of a serial connection cable (D), to a data storing and processing module (E). According to the invention, the method comprises the following stages: starting, calibrating/gauging, the working procedure and the evaluation, an algorithm (F) stored in the memory of a programmer (22) as a computer program being employed for carrying out said stages.
Patent RO-127124-A0 (RO)
Title: Process for making a passive radiator with free cooling
Inventor: SCHEUSAN EUGEN
IPC: F21V29/505
Filed: 2011-10-06
Abstract: The invention relates to a process for making a passive radiator employed for cooling heated power LEDs with operating conditions of 1...100 W. According to the invention, the process consists in making a metal structure of a radiator consisting of a base plate (2) made of aluminium and some cooling fins (3) joined to one another in a number of joining points (1), by means of a press with pneumo-hydraulic cylinder, a punch and a counter punch.
Patent RO-129266-A0 (RO)
Title: Test dummy biofidelic neck technical system for experimental tests
Inventor: CIUNEL STEFANITA
IPC: G09B23/32
Filed: 2013-08-13
Abstract: The invention relates to a system represented by a neck of a dummy which is used for experimental tests in any field of interest. According to the invention, the system consists of three subassemblies (A1, A2 and A3), the first subassembly (A1) comprises seven cervical vertebrae (C1, C2, C3, C4, C5, C6 and C7), each having a certain constructive shape and four intervertebral discs (8, 9, 10 and 11) made of a material having physical, chemical, viscoelastic and mechanical properties compatible to the human intervertebral discs, between the first two vertebrae (C1 and C2) there are no discs, the second subassembly (A2) comprises several flanges (14, 15, 17 and 19) and a driving motor (18) which carries out a rotary motion about its own axis and the third subassembly (A3) comprises some elastic elements (22) made of a shape-memory material which are fixed on the cervical vertebrae (C1...C7), in groups of five, diametrically opposed, on two perpendicular directions, having a certain configuration (C3-C6, C5-C7, C4-C6, C3-C5 and C4-C7), simulating the action of cervical muscles.
Patent AP-2002002452-A0 (AP)
Title: The method of treating drug resistant mycobacterium tuberculosis infection.
Inventor: KHAMAR BAKULESH MAFATLAL
IPC: A61P31/06
Filed: 2001-06-26
Abstract: Multidrug resistance to anti-tuberculous drugs poses threat in the treatment of tuberculosis. These strains are resistant to at least tow first line anti-tuberculous drugs such as inh and rifampicin. Frequently, such mdr strains show resistance to all commonly used firstline agents i.E inh, rifampicin, streptomycin, ethambutol and pyrazinamide. Isoniazid is the most widely used anti-tuberculous drug. Resistance to isoniazid can occur by increased expression on inha or by mutations that lower the enzyme's affinity to nadh. Mutatios in katg, which encodes catalase peroxidase, is the most common source of resistance. Another mechanism of isoniazid resistance occurs by defects in nadh dehydrogenase (ndh)of the respiratory chain.INcreases expression of ahpc has been suggested as another mechanism of inh resistance in mycobacteria. The present invention provides method of treating drug resistance for mycobacterium tuberculosis infection. According to present invention, a method is provided to employ penicillin with inh. This reduces the mic of inh and makes resistant organisms sensitive. The level of penicillins required for reversal of inh resistance is kown to be achieved and maintained by therapeutic doses of penicillins.
Patent MA-22917-A1 (MA)
Inventor: HELMUT KLIMMEK
IPC: C09K23/52
Filed: 1993-06-30
Abstract: PCT No. PCT/EP93/01642 Sec. 371 Date Dec. 29, 1994 Sec. 102(e) Date Dec. 29, 1994 PCT Filed Jun. 26, 1993 PCT Pub. No. WO94/01476 PCT Pub. Date Jan. 20, 1994The present invention relates to water-soluble, acid-groups-containing graft copolymers which are at least partially biodegradable and are based on sugars and monoethylenically unsaturated carboxylic acids, sulfonic acids and/or phosphonic acids or the salts of said acids as well as optional further monomers. The present invention further relates to a process for producing the graft copolymers at temperatures of up to 200 DEG  C. by means of radical polymerization initiators, in that a total mixture of 5-60 %-wt. mono-, di- and oligosaccharides, the derivatives thereof or the mixtures thereof, and 95-40 %-wt. of a monomer mixture comprising at least one monoethylenically unsaturated carboxylic acid, at least one monoethylenically unsaturated sulfonic acid, one monoethylenically unsaturated sulfuric acid ester and/or vinylphosphonic acid or the salts of said acids with monovalent cations, as well as optional further monomers is polymerized. The present invention further relates to the use of the graft copolymers in aqueous systems, for binding multivalent metal ions, inhibiting the water hardness, as additive in detergents and cleaning agents, as textile auxiliary, dispersing agent, in particular for pigments, and as auxiliary agent in the production of paper and leather.
Patent MA-27612-A1 (MA)
Inventor: LEBET ALAIN
IPC: A61B17/92
Filed: 2005-07-15
Abstract: The device has a strike unit (2) to strike a shock wave generator unit (3) for creating waves to transmit to an object to be disintegrated by a shock wave transmitting unit (4). The strike unit is moved by expanding gas under high pressure introduced in an accumulation unit (5) by a gas expansion unit (7), before producing each shock wave. The gas under high pressure is supplied to the unit (5) from a storage unit (6). The stored gas is freed by manual operation of a control unit (8) that is in contact with the accumulation unit (5) and the strike unit (2).
Patent MA-38299-A1 (MA)
Title: Système suiveur solaire photovoltaïque, et procédés d'installation ou d'utilisation d'un tel système suiveur photovoltaïque solaire
Inventor: MENARD ETIENNE
IPC: F24J2/54
Filed: 2014-02-05
Abstract: L'invention concerne un système photovoltaïque solaire à suivi, et des procédés d'installation ou d'utilisation d'un tel suivi comprenant au moins une unité suiveuse à axe double maintenant un réseau de modules photovoltaïques alignés sur le soleil. Ladite unité suiveuse comprend : une paire de sous-cadres portant des modules photovoltaïques, un tube de torsion portant lesdits sous-cadres pivotant autour d'un axe de rotation primaire, une structure de poteau fixée et s'étendant verticalement au-dessus d'une base d'ancrage et étant connectée de manière rotative audit support longitudinal, des moyens de rotation secondaire qui commandent l'orientation desdits sous-cadres autour d'un axe de rotation secondaire correspondant desdits sous-cadres, ledit axe de rotation secondaire étant orthogonal audit axe de rotation primaire et à des moyens d'actionneur pour commander lesdits moyens de rotation primaire et secondaire. Les axes de rotation secondaire sont situés à chaque extrémité dudit tube de torsion, ladite structure de poteau étant centrée par rapport auxdits sous-cadres et lesdits moyens d'actionneur des moyens de rotation à la fois primaire et secondaire étant linéaires.
Patent MA-39213-A1 (MA)
Title: Mélanges primaires bitume-polymère, utiles pour la préparation de liants bitume-polymère, produits obtenus a partir de ces mélanges primaires
Inventor: LOUP FRÉDÉRIC
IPC: C08L95/00
Filed: 2015-01-21
Abstract: L'invention vise à fournir à un moindre coût de nouveaux mélanges primaires utiles pour la préparation de bitumes-polymères. Pour ce faire, le mélange primaire selon l'invention comprend : (a) au moins 25 % en poids, de préférence de 25 à 80 % en poids, de polymère, (b) au moins une résine tackifiante thermoplastique de masse moléculaire moyenne comprise entre 100 et 3 000 g/mol, (c) et/ou un ou plusieurs (mono) esters alkyliques -de préférence méthyliques- d'acides gras en c16-c18, en particulier d'huile de tournesol, d'huile de lin, d'huile de colza, d'huile de soja, et/ou d'huile de tournesol isomérisée ou non; l'ester (c) étant nécessairement présent lorsque la résine tackifiante (b) a un indice d'acide mesuré selon la norme nf en iso 660 inférieur à 50 mg koh/g. L'invention a également pour objet les bitumes-polymères, les émulsions, les enduits/enrobés obtenus à partir de ce mélange primaire et leurs procédés de préparation.
Patent MA-39407-A1 (MA)
Title: Compositions de cyclodextrine et de dérivés de budésonide et procédés associés
Inventor: MAES PAUL
IPC: A61P11/00
Filed: 2015-03-30
Abstract: La présente invention concerne de nouvelles compositions pharmaceutiques utiles, formulées avec un composé de cyclodextrine et un dérivé de budésonide pour le traitement et/ou la prévention de maladies inflammatoires pulmonaires. La présente invention concerne également une nouvelle technique analytique utile destinée à la détection et à la quantification de ??-ß-cd en solution. Plus spécifiquement, la présente invention concerne l'utilisation d'une analyse 1h rmn validée pour la détection et la quantification de cyclodextrines directement dans des formulations pharmaceutiques sans étapes d'extraction ou de séparation pour des formulations liquides.
Patent UY-23759-A1 (UY)
Title: Derivados de amida heterociclica
IPC: C07D275/00
Filed: 1994-04-13
Abstract: Procedimiento para producir derivados de amida heterocíclica y particularmente amidas derivadas de ácidos benzoheterociclilalcanoicos (y tetrazoles y acilsulfonamidas relacionados) de estructura general representada en la figura 1, así como o una sal farmacéuticamente aceptable de dichos compuestos, donde: R1.L representa radicales amidicos; R2 es hidrógeno, halógeno, alquilo C1-4 o alcoxi C1-4; Q es fenilo optativamente sustituido unao más veces; A1 es alquileno C1-2 o vinileno; A2 es metileno, vinileno o un enlace directo a M; M es un grupo acídico. El procedimiento consiste, entre otras posibilidades: a-	para aquellos compuestos donde M es un grupo ácido carboxílico, descomponer en un éster adecuado, acilar una amina de fórmula (IV) representada en la figura 2; b-	para un compuesto donde M es un radical 1H-tetrazol-5-il hacer reaccionar un derivado ciano de fórmula general (VII) con un un azido de metal alcalino representado en la figura 3. Ejemplo no limitante de un compuesto preparado según la invención: 4-(5-hexanamidoindol-3-ilmetil)-3-metoxibenzoato de metilo. Estos compuestos antagonizan las accciones farmacológicas de uno o más de los metabolitos del ácido araquidónico conocidos como leucotrienos, por tanto estos compuestos son útiles en el tratamiento de enfermedades alérgicas o inflamatorias o condiciones de shock endotóxico o traumático.
Patent UY-25197-A1 (UY)
Title: Un procedimiento para mejorar la producción de 5r clavams
Inventor: BARRY BARTON
IPC: A61K31/424
Filed: 1998-09-30
Abstract: La presente invención se refiere a nuevos genes bacterianos y procedimiento para mejorar la fabricación de clavams, por ejemplo, ácido clavulánico útil como antibiótico. También proporciona nuevos organismos capaces de producir cantidades incrementadas de ácido clavulánico. Un proceso para mejorar la producción de 5R clavam en un microorganismo adecuado que comprende la manipulación de ADN que comprende uno o más genes específicos para la biosíntesis de 5R clavam en S. Clavuligerus que no es esencial para la biosíntesis de 5R clavam, y su inclusión en dicho microorganismo. Dicho proceso comprende la disrupción u otra manera de hacer defectuosas las regiones de ADN que flanquean a cas1. Se presenta un proceso en el que el 5S clavam es clavam-2-carboxilato y/o 2-hidroximetilclavam. Y un proceso para la preparación de una composición que comprende clavulnato de potasio y amoxicilina, comprendiendo dicho proceso la producción de ácido clavulánico y en adelante convertirlo en sal de potasio y la sal de potasio con amoxicilina.
Patent UY-27402-A1 (UY)
Title: Composiciones farmacéuticas de amlodipina y atorvastatina
Inventor: ALANI LAMAN
IPC: A61J3/06
Filed: 2002-07-30
Abstract: Esta invención se refiere a composiciones farmacéuticas que comprenden amlodipina y sus sales farmacéuticamente aceptables, y atorvastatina y sus sales farmacéuticamente aceptables, y un procedimiento para la preparación de las mismas, estuches de ensayo que contienen tales composiciones, así como métodos para usar tales composiciones para tratar sujetos que padecen de angina de pecho aterosclerosis, hipertensión combinada e hiperlipidemia y/o hipercolesterolemia y para tratar sujetos que presentan síntomas de riesgo cardíaco, incluidos sujetos humanos.
Patent UY-28134-A1 (UY)
Title: Formas de dosificación que comprenden un inhibidor de la ptec y un inhibidor de la hmg-coa- reductasa
Inventor: FRIESEN DWAYNE THOMAS
IPC: A61K9/16
Filed: 2003-12-18
Abstract: Una forma de dosificación comprende (1) una despersión sólida amofa que comprende un inhibidor de la proteína de transferencia de ésteres de colesterilo y un polímero ácido potenciador de la concentración, y (2) un inhibidor de la HMG-CoA-reductasa. La dispersión sólida amorfa y el inhibidor de la HMG-CoA-reductasa se combinan en la forma de dosificación de modo que la dispersión sólida amorfa y el inhibidor de la HMG-CoA-reductasa están sustancialmente separados entre sí en la forma de dosificación.
Patent UY-30091-A1 (UY)
Title: Compuestos dímeros agonistas de los receptores de los fgf (fgfr), su proceso de preparación y su aplicación en terapéutica
Inventor: PIERRE FONS
IPC: C07D471/04
Filed: 2007-01-12
Abstract: Compuestos agonistas de los receptores FGF que responden a la fórmula general M1-L-M2 en la que M1 o M2 idénticos o diferentes representan cada uno independientemente el uno del otro una unidad monómera que responde a la fórmula general M. Proceso de preparación y aplicación en terapéutica.
Patent UY-30873-A1 (UY)
Title: Proceso y dispositivo para reutilizacion del efluente liquido generado en el proceso de ennoblecimiento textil, lavanderia, tintoreria y estamparia.
Inventor: SANTOS LEANDRO ZANINI
IPC: C02F9/00
Filed: 2008-01-16
Abstract: Nuevo proceso y dispositivo industrial, comercial y/o residencial, para la realizacion del mismo, aplicado al tratamiento para reciclaje y reutilizacion del agua en los procesos de lavandería, tintorería y estamparía general y en especial en el área textil. Este informe descriptivo se refiere a un nuevo proceso y dispositivo asociado destinado a la reutilizacion del efluente líquido generado en especial en el proceso de ennoblecimiento textil, lavandería, tintorería y estamparía así como para aplicacion en la reutilizacion de efluentes líquidos en general con las características de los efluentes de la industria textil