Patent EA-002660-B1 (EA)
Title: Dyes
Inventor: HOEFFKES HORST
IPC: A61K8/00
Filed: 1998-07-22
Abstract: 1. An oxidation colorant for keratin fibers, in particular for human hair, comprising at least one color formative component in aqueous carrier, characterized in that  (a) it contains a at least one 5,6-dihydroxyindoline derivative corresponding to formula (I):   wherein independently of one another R<1> is hydrogen, an alkyl group with 1-4 carbon atoms or hydroxyalkyl group with 1-4 carbon atoms, R<2> is hydrogen, or hydroxycarbonyl group, wherein hydroxycarbonyl group can present as a salt with a physiologically compatible cation, R<3> is hydrogen or an alkyl group with 1-4 carbon atoms, R<4> is hydrogen, an alkyl group with 1-4 carbon atoms or a group -CO-R<6> where R<6> is an alkyl group with 1-4 carbon atoms, and R<5> is a group as for R<4>, or a physiologically compatible salt of said compounds with an organic or inorganic acid; and (b) no primary intermediate oxidation dye precursors. 2. An oxidation colorant according to Claim 1, wherein the compound corresponding to formula (I) is selected from the group consisting of 5,6-dihydroxyindoline, N-methyl-5,6-dihydroxyindoline, and physiologically compatible salts thereof. 3. An oxidation colorant according to Claim 1 or 2, wherein the color formative component is selected from the group consisting of 1-naphthol, pyrogallol, 1,5-dihydroxynaphthalene 2,7-dihydroxynaphthalene, 1,7-dihydroxy-naphthalene, 5-amino-2-methylphenol, 5-amino-2-methyl-4-chlorophenol, m-aminophenol, resorcinol, resorcinol monomethyl ether, m-phenylenediamine, 1-phenyl-3-methyl-pyrazolone-5, 2,4-di-chloro-3-aminophenol, 1,3-bis-(2,4-diaminophenoxy)-propane, 4-chloro-resorcinol, 2-chloro-6-methyl-3-aminophenol, 2-methylresorcinol, 5-methylresorcinol, 2,6-dihydroxypyridine, 2,6-diaminopyridine, 2,4-diaminophenoxyethanol, and physiologically compatible salts thereof. 4. An oxidation colorant according to Claim 3, wherein color formative component is selected from the group consisting of 2,4-diaminophenoxyethanol, resorcinol, 2-methyl-resorcinol, 2,5-dimethylresorcinol, 4-chlororesorcinol, 5-amino-2-methyl-phenol, 5-amino-2-methyl-4-chlorophenol, 2-chloro-6-methyl-3-aminophenol, m-aminophenol, 1-naphthol, 2,7-dihydroxynaphthalene and physiological compatible salts thereof. 5. An oxidation colorant according to any of Claims 1-5, characterized in that the compound of formula (I) is comprised in the amounts of 0.05% to 10% by weight, preferably 0.2% to 5% by weight, and color formative components - 0.01% to 20% by weight, preferably 0.2% to 5% by weight, in each case calculating for oxidation colorant in total. 6. The use of the compound according to any of Claims 1-5 for coloration of human hair. 7. The method for coloration of human hair using the compound according to any of Claims 1-5, characterized in that the formation of the colorant is carried out with atmospheric oxygen. 8. The method for coloration of human hair using the compound according to any of Claims 1-5, characterized in that the formation of the desired color is carried out by means of repeated applying to the hair a compound and in each case with further oxidizing with atmospheric oxygen.