baber/WOPTO huggingface dataset:
Patent CA-3087642-A1 (CA)
Inventor: GALBREATH-O'LEARY BRADEN J
IPC: C02F3/02
Filed: 2020-07-22
Abstract: The disclosed lagoon biological treatment system helps existing wastewater treatment facilities meet stricter discharge permits mandated by the EPA  utilizing a facility's existing wastewater treatment infrastructure. Influent is pumped into and processed in an aerated or non-aerated lagoon system, thus initially treating the wastewater to reduce BOD5 (Biochemical Oxygen Demand) and TSS (Total Suspended Solids) to approximately 20-30 mg/L. Then the wastewater is transferred to and processed in a nitrification reactor, where sufficient nitrifying bacteria is present to reduce nitrogen levels to regulation-acceptable levels without needing to regulate temperature of the water in the nitrification reactor. Wastewater may also be further processed in a denitrifying reactor if necessary to meet local requirement.  Post-nitrification polishing of the wastewater is foregone.
Patent CA-3089908-A1 (CA)
Inventor: AVERAY ROBERT DENNIS
IPC: H03M1/12
Filed: 2019-02-08
Abstract: A direct-digital receiver architecture incorporating an analog to digital converter including: input signal reception unit for receiving an analog input signal; an analog frontend applying a variable gain factor to the analog input signal so as to produce a gain adjusted input signal; an analog to digital converter converting the gain adjusted input signal to a corresponding digital signal; a gain level unit for determining the variable gain factor via monitoring of the corresponding digital signal; a gain scaling unit for determining a scale factor depending on the gain level; a gain factor multiplier for multiplying the corresponding digital signal by a scale factor to produce a scaled digital signal; time alignment of analog front-end variable gain factor into to the digital signal processing train; a digital signal processing train cognisant of the dynamic range of the ADC, dynamic range of the analog-front and gain factor and the gain factor for the time domain sample being processed.
Patent CA-3090482-A1 (CA)
Inventor: CHEN PING
IPC: C07D239/94
Filed: 2019-02-07
Abstract: Compounds of the general formula (l):    are provided, together with processes for the preparation of these compounds, compositions containing these compounds, and the uses of these compounds as KRAS  inihibitors, which may be used in the treatment of cancer.
Patent CA-3093623-A1 (CA)
Inventor: BENSTEAD EVAN
IPC: E03C1/04
Filed: 2020-09-18
Abstract: A faucet includes a faucet body and a spout attached to the faucet body and extending from the faucet body along an axis. The spout has an interior defining a fluid path. A cartridge seat is positioned within the faucet body and contacts a valve cartridge positioned offset from the axis. The valve cartridge is fluidically connected to the cartridge seat. A  flexible tube fluidically connects between a fluid outlet of the cartridge seat and the spout, and is positioned entirely within a cavity formed by the faucet body and the spout.
Patent CA-3093989-A1 (CA)
Title: Gas-liquid falling film equilibration system and methods of use
Inventor: MILLER ALEXANDER WHITMAN
IPC: G01N37/00
Filed: 2019-03-21
Abstract: The current disclosure provides a gas-liquid falling film equilibration apparatus, systems incorporating the apparatus, and methods of their use. The apparatus comprises a chamber, an equilibration member within the chamber, liquid and gas inlet and outlets, such that a liquid introduced into the chamber from the liquid inlet contacts the upper portion of the outer surface of the equilibration member. The apparatus finds use in the measurement of dissolved gases in a variety of liquids including the measurement of carbon dioxide in water.
Patent CA-3096561-A1 (CA)
Inventor: VAN LOC
IPC: C12Q1/02
Filed: 2019-03-19
Abstract: A method for obtaining an animal model from conditionally reprogrammed tumor cells for screening anti-tumor drugs and a method for screening anti-tumor drugs using the same.
Patent CA-3096886-A1 (CA)
Title: Systeme et methode de chirurgie refractive au laser basee sur un nomogramme
Inventor: RIEDEL PETER
IPC: A61F9/008
Filed: 2019-05-30
Abstract: La présente invention concerne un système de chirurgie réfractive au laser comprenant un processeur ayant accès à des supports de mémoire stockant des instructions ou des ensembles d'instructions exécutables par le processeur pour identifier un paramètre chirurgical; corriger le paramètre chirurgical sur la base d'un nomogramme spécifique du système de chirurgie réfractive au laser pour fournir un paramètre chirurgical corrigé basé sur le nomogramme; stocker le paramètre chirurgical et le paramètre chirurgical corrigé basé sur le nomogramme dans le support de mémoire en tant que données pour un patient ou pour un ou les deux yeux du patient; et comparer le paramètre chirurgical et le paramètre chirurgical corrigé basé sur le nomogramme pour générer une représentation graphique du paramètre chirurgical, un paramètre de résultat cible associé au paramètre chirurgical, ou les deux, et le paramètre chirurgical corrigé basé sur le nomogramme, pour générer un avertissement sur la base d'une comparaison du paramètre chirurgical corrigé basé sur le nomogramme au paramètre chirurgical ou à une valeur absolue, ou les deux. L'invention porte également sur des méthodes d'utilisation du système.
Patent CA-3097086-A1 (CA)
Title: Method and system for drying mine tailings
Inventor: FRIED SPENCER
IPC: B03B9/02
Filed: 2019-04-23
Abstract: A method and system to treat and dry fines tailings generated from mining operations, comprising spraying the tailings material into a vacuum chamber operated at less than atmospheric pressure to separate evaporated water from the residual solid materials.
Patent CA-3097149-A1 (CA)
Title: System and methodology to integrate m-tool nozzle with sand screen
Inventor: DIKSHIT ASHUTOSH
IPC: B01D35/02
Filed: 2020-10-23
Abstract: ABSTRACT  A sand control assembly includes a base pipe having at least one perforation, a housing, and at least one inflow control device integrated within the housing via an associated ring secured to the housing and the base pipe, the at least one inflow control device and the associated ring creating a seal. The housing is disposed around the exterior of the base pipe, and the housing is secured to a bypass ring at a first end of the housing and secured to the base pipe at a second end of the housing via a weld end ring. A longitudinal axis of the at least one inflow control device is parallel to a longitudinal axis of the base pipe. Date Reçue/Date Recieved 2020-10-23
Patent CA-3098676-A1 (CA)
Inventor: SPECTOR MARK
IPC: A61F5/451
Filed: 2019-04-29
Abstract: Selon un exemple de l'invention, un dispositif de collecte de fluide comprend une barrière imperméable aux fluides qui définit au moins partiellement une chambre. La barrière imperméable aux fluides définit également une ouverture s'étendant à travers elle. L'ouverture est conçue pour être positionnée adjacente à un urètre féminin ou avoir un urètre mâle positionné à travers ladite ouverture. Le dispositif de collecte de fluide comprend également un conduit au moins partiellement disposé dans la chambre. Le conduit définit au moins une ouverture qui permet à l'intérieur du conduit d'être en communication fluidique avec la chambre. Le dispositif de collecte de fluide comprend en outre une vanne. La vanne comprend une première ouverture reliée au conduit et une seconde ouverture qui peut être reliée par fluide à au moins un élément parmi une source d'air, une source de vide ou un récipient de stockage de fluide. La vanne est conçue pour réguler un écoulement de fluide à travers le conduit en réponse à une direction provenant d'un utilisateur.
Patent CA-3101475-A1 (CA)
Inventor: CHEN THOMAS
IPC: A61P35/00
Filed: 2019-02-07
Abstract: La présente invention concerne l'utilisation de monoterpène, de sesquiterpène ou de leurs dérivés pour perméabiliser la barrière hémato-encéphalique. Dans un mode de réalisation, on utilise de l'alcool périllylique avant ou concurremment avec un agent thérapeutique qui est un lymphocyte à récepteur antigénique chimérique (CAR-T), afin de traiter un cancer du système nerveux central chez un mammifère. Le cancer du système nerveux central peut être un cancer du cerveau. L'alcool périllylique peut être administré par injection intra-artérielle et utilisé à une dose allant de 0,050 à 500 mg/kg du poids corporel. Dans un autre mode de réalisation, l'alcool périllylique est utilisé environ 0,2 à 60 minutes avant l'utilisation du CAR-T, et l'alcool périllylique est utilisé 1 à 15 minutes avant l'utilisation du CAR-T. Selon les modes de réalisation de la présente invention, l'alcool périllylique et le CAR-T peuvent être utilisés séparément ou concurremment.
Patent CA-3111385-A1 (CA)
Title: Sustained-release injectable antibiotical formulation
Inventor: FRIEDMAN MICHAEL
IPC: A61P31/04
Filed: 2019-09-05
Abstract: Provided herein are compositions of injectable antibiotics for veterinary use. The compositions are characterized by forming a gel at animal physiological temperature, said gel being characterized by a stable and repeatable release profile of the antibiotic. The compositions comprise high loading of drug in poloxamer solutions with addition of a co-solvent, and preferably with an addition of a cellulose derivative at least partially soluble in organic solvents. Methods of treatment of veterinary infections are also provided.
Patent CA-3112076-A1 (CA)
Inventor: DELEURME JESSE PETER
IPC: B62D37/02
Filed: 2021-03-16
Abstract: Drag reducing walls over the gap between a tractor and trailer are pivotally mounted on each side of the tractor to extend rearwardly so as to position a rear edge of each wall adjacent a corresponding side of the trailer when the tractor is in a position aligned with the trailer. At least one wheel is mounted on the rear edge of each wall so that the at least one wheel on one of the walls contacts, so as to roll over, the corresponding side of the trailer and then the face of the trailer as the tractor turns relative to the trailer, and then as the tractor re-aligns with the trailer contacts so as to roll over the face of the trailer and then the side of the trailer so as to return to the aligned position.
Patent CA-3112310-A1 (CA)
Inventor: SALZER BENJAMIN
IPC: A61K39/00
Filed: 2019-10-04
Abstract: Disclosed is a group of chimeric antigen receptors (CARs) consisting of two, three or four CAR molecules, wherein each member of the group of CARs is different in its amino acid sequence from one another, and wherein each of the CAR molecules of the group comprise at least a transmembrane domain and an ectodomain, wherein the ectodomain comprises one or two antigen binding moieties and/or one or two binding sites to which other polypeptides each comprising at least an antigen binding moiety are able to bind; wherein the ectodomain of each CAR molecule of the group in its prevalent conformation is free of cysteine amino acid moieties which are able to form intermolecular disulphide bonds with other CAR molecules of the group, respectively, and wherein each CAR molecule of the group comprises at least one heterodimerization domain.
Patent CA-3112796-A1 (CA)
Inventor: CHOI YOUNG IL
IPC: A61K9/00
Filed: 2019-10-11
Abstract: La présente invention concerne une composition pharmaceutique pour prévenir ou traiter les maladies rhumatismales inflammatoires, comprenant un inhibiteur de l'histone désacétylase et du méthotrexate en tant que principe actif ; une méthode de traitement utilisant la composition ; et une utilisation de la composition dans la préparation d'un médicament pour le traitement des maladies rhumatismales inflammatoires, la composition pharmaceutique selon la présente invention présentant un excellent effet sur la prévention ou le traitement des maladies rhumatismales inflammatoires.
Patent CA-3116757-A1 (CA)
Title: System and method for machine learning based image generation
Inventor: MASCARENHAS SUSANNA
IPC: G06F40/40
Filed: 2021-04-30
Abstract: An artificial intelligence and machine learning system and method for image generation. The method comprising receiving a word comprising language characters, processing each of the characters in the word into visual elements, generating an image using the visual elements of the characters. The AI system may receive a name of a person such as 'Amy' and may process the name into visual elements that when positioned and oriented relative to each other, form a face.  The letter 'a' may be used as the outline of the face, the letter 'm' positioned within the 'a' may be used to depict closed eyes and the letter 'y' positioned within the 'a' and below the 'm' may be used to depict a nose and mouth.
Patent CA-3118016-A1 (CA)
Title: A slurry drying plant, a method for drying slurry and use of a slurry drying plant
Inventor: AHRENFELDT JESPER
IPC: F26B17/18
Filed: 2018-11-01
Abstract: Disclosed is a slurry drying plant (1) comprising a slurry extruder (3) including a slurry inlet (2) and conveying means (4) arranged to convey the slurry through the slurry extruder (3) and force the slurry out of a plurality of exit openings (5) of the slurry extruder (3) to form a plurality of slurry strings (7), wherein the slurry strings (7) are forced out into a drying chamber (8) in which the plurality of slurry strings (7) is dried. The slurry drying plant (1) further comprises slurry heating means (6) comprising flow means for passing superheated steam past the slurry strings (7) in the drying chamber (8), and inlet pressure detection means (9) for detecting a slurry inlet pressure at the slurry inlet (2). The slurry drying plant (1) also comprises control means (17) arranged to control the conveying speed of the conveying means (4) in response to the slurry inlet pressure. Furthermore, a method for drying slurry and use of a slurry drying plant (1) is disclosed.
Patent CA-3118389-A1 (CA)
Inventor: LUO QINGMING
IPC: G02B21/00
Filed: 2019-07-30
Abstract: The present disclosure discloses a high-throughput optical sectioning imaging method and imaging system. The method includes: modulating a light beam into a modulated light beam capable of being focused on a focal plane of an objective lens and being defocused on a defocusing plane of the objective lens, the modulated light beam having incompletely identical modulated intensities on the focal plane of the objective lens;  imaging, in different rows of pixels, a sample under illumination of the modulated light beam to obtain sample images in the different rows of pixels; obtaining focal plane images of sample images in the different rows of pixels by demodulation of the sample images according to a demodulation algorithm. The system includes a light beam modulation module, an imaging module and a demodulation module. The present disclosure performs illumination by a light beam having incompletely identical modulated intensities, images a same sample in different rows of pixels, and obtains a focal plane image by using a simpler demodulation algorithm, which simplifies a structured light reconstruction algorithm, improves reconstruction efficiency, and improves an imaging speed of large-size samples.
Patent CA-3120631-A1 (CA)
Inventor: ZABLOTSKAIA POLINA
IPC: G06T7/00
Filed: 2021-06-02
Abstract: Systems and methods for unsupervised multi-object scene decomposition that involve a spatio-temporal amortized inference model for multi-object video decomposition. Systems and methods involve a new spatio-temporal iterative inference framework to jointly model complex multi-object representations and the explicit temporal dependencies between the frames. Those dependencies improve overall quality of decomposition, encode information about object dynamics and can be used to predict future trajectories of each object separately. Additionally, the model can generate precise estimations and output data even without color information. The model has scene decomposition, segmentation and future prediction capabilities. The processor can use the model to simulate future frames of the scene data.
Patent CA-3124616-A1 (CA)
Title: Therapies for squamous cell carcinomas
Inventor: GUALBERTO ANTONIO
IPC: A61P35/00
Filed: 2019-12-20
Abstract: The present invention relates to the field of cancer therapy. Specifically, provided are methods of neoadjuvant therapies or adjuvant therapies to treat squamous cell carcinoma in a subject with a farnesyltransferase inhibitor (FTI) that include determining whether the subject is likely to be responsive to the FTI treatment based on the H-Ras mutant allele frequency.
Patent CA-3126096-A1 (CA)
Inventor: DAIN DAVID
IPC: C07D265/30
Filed: 2011-04-12
Abstract: Il est décrit des procédés de fabrication de viloxazine et de ses divers sels, ainsi que des composés apparentés à la viloxazine, tels que de nouveaux produits réactionnels intermédiaires et des polymorphes de celle-ci. En particulier, les procédés fournissent un Ingrédient Pharmaceutique Actif sensiblement pur de viloxazine HCl tout en évitant des impuretés non désirables. Il est également décrit des procédés de séparation, didentification et de caractérisation de nouveaux polymorphes de viloxazine. Il est également décrit des procédés de synthèse, d'identification et de caractérisation de nouveaux intermédiaires de viloxazine, ainsi que certains métabolites et précurseurs de métabolites importants de viloxazine.
Patent CA-3127164-A1 (CA)
Title: Low pressure starter device for pneumatic pumps
Inventor: GONZALEZ-MORATIEL ALVAREZ ALBERTO
IPC: F16K11/052
Filed: 2020-01-20
Abstract: The invention relates to a low-pressure starter device for pneumatic pumps with a pivoting directional air-control valve, characterised in that the low-pressure starter system consists of a retractable push piston actuated by a variable-tension spring that exerts pressure on the shaft of a pivoting element of the body of the directional valve, during start-up, in an end operating positions, said device being formed by a retractable piston, a sealing gasket, a spring and a spring stop.
Patent CA-3127768-A1 (CA)
Inventor: ABRAMS ROBERT S
IPC: A61J1/14
Filed: 2020-01-24
Abstract: La présente invention concerne un système de récipients, de raccords ou d'autres équipements caractérisé en ce qu'au moins certaines surfaces communes se trouvent en contact avec un produit biopharmaceutique pendant la fabrication, l'emballage, la distribution et l'évaluation de produits biopharmaceutiques. L'invention concerne également des procédés de production de ces systèmes et de personnalisation de surfaces de contact destinées à être utilisées dans ceux-ci.
Patent CA-3129036-A1 (CA)
Inventor: WILKINSON GREY
IPC: C07K14/14
Filed: 2020-02-21
Abstract: L'invention concerne des méthodes de traitement du cancer chez un sujet. Les procédés comprennent l'administration au sujet d'une ou de plusieurs doses d'un virus oncolytique (par exemple, dans un cycle de traitement initial) ; la sélection d'un sujet avec une population de lymphocytes T présentant une clonalité périphérique élevée ; et l'administration au sujet d'une population de lymphocytes T présentant une clonalité périphérique élevée et une ou plusieurs doses ultérieures du virus oncolytique (par exemple, dans un second cycle de traitement).
Patent CA-3130825-A1 (CA)
Inventor: GREY SHANE T
IPC: C12Q1/6886
Filed: 2020-02-21
Abstract: La présente invention se rapporte d'une manière générale au domaine de 'immunothérapie. En particulier, la présente invention concerne 13 variants nucléotidiques uniques (SNV) à l'Intérieur de la séquence de codage A20 pouvant affecter de manière différente le système immunitaire. L'expression différente des SNV Identifiés peut être utilisée pour "calibrer" le système immunitaire d'un sujet, par exemple, augmenter ou diminuer la sensibilité et/ou la résistance du système immunitaire. L'invention concerne également des procédés de modulation du système immunitaire d'un sujet par modulation du profil d'expression du SNV a20 chez le sujet. Les procédés et les réactifs de l'invention sont utilisés dans le traitement et/ou la gestion de maladies/états tels que, par exemple, le cancer, une maladie auto-immune, une infection pathogène et un rejet de greffe.
Patent CA-3130942-A1 (CA)
Title: Access control with reader to reader communication
Inventor: SHAIKH NADEEM
IPC: G01S11/00
Filed: 2021-09-15
Abstract: An access control system and a method for operating an access control system are provided. The access control system includes a first access control device and a second access control device, each configured to receive a signal (e.g., an access credential) from a user device. The signal has a first signal strength at the first access control device and a second signal strength at the second access control device. Each of the first access control device and the second access control device include a processor configured to compare the first signal strength and the second signal strength to determine whether the first access control device or the second access control device is closest to the user device. The processor of the access control device closest to the user device may be configured to determine whether the access credential is authorized.
Patent CA-3131702-A1 (CA)
Inventor: VILLARO AMURRIO MIKEL
IPC: F02C7/24
Filed: 2021-09-23
Abstract: The invention provides a guide vane for a vane assembly of a turbo machine, the guide vane comprising: an aerofoil body comprising: a forward portion, a rear portion, and opposite outer surfaces, extending between the forward portion and the rear portion, a liner shaped with a sheet like geometry, the liner being configured for being fixed to the aerofoil body, the liner comprising: a first portion configured for being connected to the forward portion of the aerofoil body, a trailing edge portion shaped with a convex geometry, a first coupling portion extending between the first portion and the trailing edge portion, and configured for being fixed to an outer surface of the aerofoil body, a second portion extending from the trailing edge portion and configured for being connected to the rear portion of the aerofoil body, wherein when the first coupling portion of the liner is fixed to an outer surface of the aerofoil body: the trailing edge portion of the liner extends from the rear portion of the aerofoil body, and the second portion of the liner is connected to the rear portion of the aerofoil body, thus forming a cavity between the rear portion of the aerofoil body and the trailing edge portion of the liner.
Patent CA-3132265-A1 (CA)
Title: Composes n-acyl-{4-[(4-aryl-phenyl)sulfonylmethyl]piperidine} et leur utilisation therapeutique
Inventor: PATEL LISA
IPC: C07D401/12
Filed: 2020-04-17
Abstract: La présente invention concerne d'une façon générale le domaine des composés thérapeutiques. Plus particulièrement, la présente invention concerne certains composés de N-acyl-{4-[(4-aryl- phényl)sulfonylméthyl]pipéridine} de la formule suivante (appelés collectivement ici composés NASMP) qui sont utiles, par exemple, dans le traitement de troubles (par exemple, de maladies) y compris, par exemple, le myélome multiple, le lymphome diffus à grandes cellules B, la leucémie myéloïde aiguë, la leucémie éosinophile, le glioblastome, le mélanome, le cancer de l'ovaire, le cancer résistant à la chimiothérapie, le cancer résistant aux rayonnements, l'arthrite inflammatoire, la polyarthrite rhumatoïde, l'arthrite psoriasique, le psoriasis, la rectocolite hémorragique, la maladie de Crohn, le lupus érythémateux disséminé (SLE), la néphropathie lupique, l'asthme, la bronchopneumopathie chronique obstructive (BPCO), l'Hidradenitis suppurativa, l'hépatite auto-immune, etc. La présente invention concerne également des compositions pharmaceutiques comprenant de tels composés, et l'utilisation de tels composés et compositions, par exemple, en thérapie.