baber/WOPTO huggingface dataset:
Patent CA-2421551-A1 (CA)
Inventor: JONES MILFORD D
IPC: A23G9/06
Filed: 2001-07-17
Abstract: A cryogenic processor (10) is provided for liquid feed preparation of a free-flowing frozen product. The cryogenic processor (10) includes a freezing chamber (12) having a substantially conical shape, at least one feed tray (48) overlying the freezing chamber (12) arranged and adapted to receive liquid composition from a delivery source (50), the tray (48) having a plurality of orifices (44) for discharge of uniformly sized droplets of the composition from the feed tray (48), whereby the droplets are delivered by gravity into the freezing chamber (12) therebelow. The cryogenic processor (10) also includes at least one sensor (66) associated with the feed tray (48) for determining a depth of liquid composition in the feed tray (48), at least one valve associated with a liquid composition delivery line (52), the valve being configured to control the rate at which liquid composition is delivered from the delivery source (50) to the feed tray (48) and a controller responsive (68) to the at least one sensor for controlling a position of the valve, and therefore the rate at which liquid composition is delivered from the delivery source (50) to the feed tray (48).
Patent CA-2422710-A1 (CA)
Title: Osteogenic fusion devices
Inventor: MCKAY WILLIAM F
IPC: A61F2/30
Filed: 2001-09-19
Abstract: An interbody osteogenic fusion device (10) is provided that includes opposite end pieces (11, 12) with an integral central element (13). The end pieces are sized to maintain the height of an intervertebral disc space. The central element has a much smaller diameter so that the osteogenic fusion device forms an annular pocket around the central element. An osteogenic material is disposed within the annular pocket (24) between the opposite end pieces. In one embodiment, the osteogenic material constitutes a collagen sheet (30) soaked in a solution containing a bone morphogenetic protein. The osteogenic fusion device is configured so that the osteogenic material is in direct contact with the adjacent vertebral bone.
Patent CA-2423045-A1 (CA)
Inventor: HAVENGA MENZO JANS EMCO
IPC: C12N15/62
Filed: 2001-09-25
Abstract: The invention provides means and methods for transduction of a skeletal muscle cell and/or a muscle cell specific precursor thereof. Provided is the use of a gene delivery vehicle derived from an adenovirus, having a tropism for said cells, for the preparation of a medicament. In a preferred aspect of the invention, said gene delivery vehicle comprises at least a tropism determining part of an adenoviral fiber protein of subgroup B and/or F. More preferably, said gene delivery vehicle comprises at least part of a fiber protein of an adenovirus of stereotype (11, 16, 35, 40 and/or 51) or a functional part, derivative and/or analogue thereof.
Patent CA-2424222-A1 (CA)
Inventor: DINSMORE CHRISTOPHER J
IPC: A61K31/506
Filed: 2001-09-28
Abstract: La présente invention se rapporte à des composés bicycliques fondus qui inhibent la prényl-protéine transférase et la prénylation de la protéine oncogène Ras. Cette invention concerne également des compositions chimiothérapeutiques contenant les composés de ladite invention ainsi que des procédés pour inhiber la prényl-protéine transférase et la prénylation de la protéine oncogène Ras.
Patent CA-2425313-A1 (CA)
Inventor: NELSON FREDERICK WILLIAM
IPC: F15B15/28
Filed: 2003-04-14
Abstract: The invention disclosed is a steering system providing steered wheel angle sensing for vehicles having a spaced pair of steered wheels, a two-way hydraulic steering cylinder operatively connected to the steered wheels, and a hydraulic circuit connected to the cylinder. The invention includes a hydraulic two-way valve, a hydraulic pump for supplying fluid under pressure to the circuit and being hydraulically connected to the valve, the cylinder having a single moveable shaft therein to move, in opposite directions to steer the wheels in one of two angular directions, a hydraulic motor in the circuit between the cylinder and the valve, an output shaft on the motor adapted to rotate in one of two directions depending on the direction of flow of fluid through the motor, and a pair of sensors adjacent the shaft to determine the direction of motion of the shaft, and hence an angular steering position of the wheels.
Patent CA-2426359-A1 (CA)
Inventor: HOLMES JOHN A
IPC: H04Q7/32
Filed: 2001-04-02
Abstract: A hand-held electronic device is provided having a keyboard optimized for use with the thumbs and an inclined thumbwheel for auxiliary data entry and selection. The keyboard preferably includes a plurality of non-uniform shaped keys, such as oblong, oval or rectangular keys, which are organized into two sets of keys that, together, form a QWERTY keyboard. The two sets of non-uniform shaped keys are tilted at complimentary angles to each other and with respect to a common vertical reference through the device. The keys are also uniformly distributed across the device to facilitate optimal thumb typing. The thumbwheel is inclined at an angle for easier operation, and is used for auxiliary data entry and menu selection.
Patent CA-2426492-A1 (CA)
Inventor: PEDERSEN ANDERS GERSEL
IPC: A61K31/216
Filed: 2003-05-08
Abstract: Provided herein is a pharmaceutical composition comprising: (a) an effective amount of one or more of acetylcholinesterase inhibitors) or a pharmaceutically effective salt thereof; and (b) an effective amount of one or more NMDA-antagonist(s). Also provided is the use of the above composition for the manufacture of a medicament for the treatment of mild cognitive impairment or dementia.
Patent CA-2430312-A1 (CA)
Inventor: BABA YOSHINOBU
IPC: G01N27/447
Filed: 2000-11-29
Abstract: To provide a method for analyzing a nucleic acid according to high throughput microcapillary electrophoresis during microchip electrophoresis under non-steady electric field, the method being capable of detecting polymorphism of a large number of genes at a high speed. The present invention is useful for the diagnosis and treatment of diseases such as detection of gene diseases and application to Taylor-made therapy.
Patent CA-2435273-A1 (CA)
Title: Thiol-based naaladase inhibitors
Inventor: SLUSHER BARBARA S
IPC: A61P25/28
Filed: 2002-01-17
Abstract: This invention relates to thiol compounds of the formulae I, II or III (in which the variables are as defined in the claims), pharmaceutical compositions and diagnostic kits comprising such compounds and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, effecting neuronal activity, effecting TGF-.beta. activity, inhibiting angiogenesis, and treating glutamate abnormalities, diabetic neuropathy, pain, compulsive disorders, prostate diseases, cancers and glaucoma.
Patent CA-2437776-A1 (CA)
Title: Protective garment, which is worn with shoulder pad having inflatable bladder, for firefighter or for emergency worker
Inventor: GRILLIOT WILLIAM L
IPC: A41F15/00
Filed: 2003-08-20
Abstract: A protective garment, such as a protective coat or protective coveralls, for a firefighter or for an emergency worker is provided with a shoulder pad, which is worn between the protective coat and a shoulder of a wearer. The shoulder pad is attached detachably, as by a hook-and-loop fastener, to a shoulder strap of suspenders worn by the wearer or to the protective garment. The shoulder pad contains a bladder, which is adapted to be inflated with a suitable fluid, preferably air, so to increase an air space between the protective coat and the shoulder of the wearer. The air space provides thermal insulation between the protective garment and the shoulder of the wearer.
Patent CA-2438648-A1 (CA)
Inventor: KOHLER BURKHARD
IPC: G02B6/122
Filed: 2002-02-11
Abstract: The invention relates to a phosphorus-containing polymer for coating dielectric materials, to processes for its preparation and to its use, as well as to an optical signal transducer having a coating of the polymer and to its use.
Patent CA-2439905-A1 (CA)
Title: Long-range prediction of fading signals
Inventor: QIU ROBERT C
IPC: H04L1/12
Filed: 2001-11-16
Abstract: The present invention is an adaptive system, which supports higher peak data rate and throughput in digital wireless communications, compared with other non-adaptive systems. One embodiment of the invention consists of three parts:  the Long Term Prediction system (114) for fast fading DS/CDMA mobile radio channel; the fast feedback system (116) to enable the adaptive transmission;  and, new system blocks (118) that are supported/enabled and changes in the existing 3GPPWCDMA system (102) specifications.
Patent CA-2440246-A1 (CA)
Title: Passive video multiplexing method and apparatus
Inventor: ODRYNA VIC
IPC: G06F3/14
Filed: 2002-03-29
Abstract: A passive video multiplexing method and apparatus for encoding video synchronization signals within a KVM extension system. A Rack Interface Pod (RIP) is provided for receiving video signals from a network server (122) and providing them to a remote user via a local area network (LAN). The analog signals received by the RIP are transmitted to a Rack Connection Manager (RCM) (116) having video processing logic, a supervisory process (94), a KVM switch system (92), and Ethernet interface circuitry (118). A plurality of ARI systems (117) are connected to the RCM (116), and a pluraltiy of network servers (122), intended to be controlled by the remote user, are connected to each ARI (117) by a respective wiring strip or Pod Expansion Module (PEM).
Patent CA-2442339-A1 (CA)
Title: Color space transformations for use in identifying objects of interest in biological specimens
Inventor: DOUGLAS JAMES
IPC: G01N33/483
Filed: 2003-09-23
Abstract: Two color transformations, as described herein, facilitate identification of the objects of interest in the biological specimen. One of the color transformations. a Minus Clear Plus One (MC-1) transformation, can be conceptualized as either translating and rotating ayes of a three-dimensional coordinate space that defines an image of the biological specimen or calculating differences between vectors in the three dimensional coordinate space that defines the image of the biological specimen. The other of the color transformations, a Quantitative Chromatic Transformation (QCT).is a colorimetric transformation that produces three new quantitities from the original red, green, and blue pixel values for each color pixel of an image. These three new quantities, X, Y, and Z can each be related to the quantitative amount of absorbing molecules sampled by that pixel. Application of one or both of the color transformations to the image of the biological specimen results in a transformed image, in which objects of interest are more readily identifiable.
Patent CA-2443374-A1 (CA)
Title: Method of fabricating workpieces with fine-grained structure
Inventor: GOLUBEV VITALY NIKOLAEVICH
IPC: B21C1/00
Filed: 2002-04-02
Abstract: The invention relates to metal forming, in particular to a method for producing metal blanks made of metal and metal alloys using plastic deformation, including long billets having a pre-prepared fine grain structure, more specifically submicro-crystalline and nano-crystalline structures. The inventive method makes it possible to produce blanks having a longitudinal stratification and an inner reinforcement, and can be used for processing blanks made of powdered metals in order to obtain a monolithic article. The plastic deformation is carried out by forming in a mould with t he aid of a profile tool arranged inside a pressing channel of the mould. Said profile tool directs a metal flow and creates a combined upset-shearing- torsion scheme of an intensive plastic deformation accompanied by restoratio n of the cross section of the blank without deforming the continuity thereof. Said method reduces costs for blank processing by using serial equipment, fo r example vertical and horizontal hydraulic presses. The inventive method make s it possible to process blanks made of difficult-to-form and low-ductility alloys, powdered metals and composite materials and to increase metal recove ry.
Patent CA-2443550-A1 (CA)
Title: Diagnosis and treatment of neural disease and injury using microvoltammetry
Inventor: PACIA STEVEN V
IPC: A61B5/00
Filed: 2002-04-08
Abstract: Devices and methods of use thereof for determining the presence and concentration of chemicals in a cell, tissue, organ or organism involve semiderivative voltammetric measurements and chronoamperometric measurements of chemicals, e.g. neurotransmitters, precursors, and metabolites. Methods of diagnosing and/or treating a subject with abnormal levels of neurotransmitters includes those having or at risk of developing epilepsy, diseases of the basal ganglia, athtoid, dystonic diseases, neoplasms, Parkinson's disease, brain injuries, spinal cord injuries, and cancer. Microvoltammetry methods may be performed in vitro, in vivo, or in situ to differentiate white matter from grey matter, diagnose brain tumors, for cancer diagnosis and treatment, and to locate a tumor's position. Broderick probes are used to determine the concentration of the material, e.g. dopamine, norepinephrine, and serotonin, in the brains of patients having epilepsy. In some embodiments of the invention, regions of the brain to be resected or to be targeted for pharmaceutical therapy are identified using Broderick probes. The invention further provides methods of measuring the neurotoxicity of a material by comparing Broderick probe microvoltammograms of a neural tissue in the presence and absence of the material.
Patent CA-2444009-A1 (CA)
Title: Method of manufacturing drag-reducing polymer suspensions
Inventor: JOHNSTON RAY L
IPC: B02C21/00
Filed: 2002-09-27
Abstract: A drag-reducing suspension is described, along with a process for manufacturing the drag-reducing suspension. The drag-reducing suspension is easily transportable, non-hazardous, easily handled, and provides a significant increase in drag-reducing capability over existing products.
Patent CA-2445007-A1 (CA)
Inventor: KONCELIK LAWRENCE J JR
IPC: A63B69/38
Filed: 2001-08-28
Abstract: L'invention concerne un dispositif (10) qui s'attache à du matériel de sport tel qu'un club de golf (18) ou une raquette de tennis (38) qui se déplace selon un mouvement de balayage dans le but de créer un son audible dans des conditions prédéterminées. Il est donc possible de produire des sons audibles suite à des augmentations subites de vitesse. Le dispositif comprend un élément de production de son (12) constitué d'une matière flexible et comprend un élément (14) servant de moyen de fixation. L'élément de production de son (12) peut être fixé de façon permanente à la pièce de matériel de sport par le biais d'un adhésif (40). De façon alternative, l'élément (14) est muni d'un moyen de fixation semi-permanent permettant de fixer et de détacher à souhait le dispositif au matériel de sport. L'élément (14) comprend une bague encliquetable ou une agrafe (24) ou une longueur de matière (2) qui peut être attachée ou enroulée autour d'une partie de matériel de sport. L'agrafe (24) comprend une ouverture rainurée (28) formée par des bras divergents flexibles (26).
Patent CA-2445168-A1 (CA)
Inventor: KNORR ANDREAS M
IPC: A61P11/00
Filed: 2002-04-24
Abstract: Human antibodies that bind to TIMP-1 can be used as reagents to diagnose and treat disorders in which TIMP-1 is elevated, such as liver fibrosis, alcoholic liver disease, cardiac fibrosis, acute coronary syndrome, lupus nephritis, glomerulosclerotic renal disease, benign prostate hypertrophy, colon cancer, lung cancer, and idiopathic pulmonary fibrosis.
Patent CA-2446698-A1 (CA)
Title: Pre-emption of user data sent in signaling channels
Inventor: SEBIRE GUILLAUME
IPC: H04L12/851
Filed: 2001-05-07
Abstract: In the LAPDm a short message service is implemented by pre-emption of every second signalling message when there is a short message to be sent. Same pre-emption mechanism is also needed when the RLC/MAC protocol is used on the data link layer instead of the LAPDm. The mechanism is provided by defining at least two different identities to be used with frames transmitted on the signalling channel; and pre-empting frames on the MAC at least on the basis of the identity relating to a frame. The identities are preferably identified on the basis of the signalling radio bearer of the frame.
Patent CA-2446984-A1 (CA)
Title: Internal riser rotating control head
Inventor: WILSON TIMOTHY L
IPC: E21B21/08
Filed: 2003-10-27
Abstract: A system and method provides a holding member for releasably positioning a rotating control head assembly in a subsea housing. The holding member engages an internal formation in the subsea housing to resist movement of the rotating control head assembly relative to the subsea housing. The rotating control head assembly is sealed with the subsea housing when the holding member engages the internal formation. An extendible portion of the holding member assembly extrudes an elastomer between an upper portion and a lower portion of the internal housing to seal the rotating control head assembly with the subsea housing. Pressure relief mechanisms release excess pressure in the subsea housing and a pressure compensation mechanism pressurize bearings in the bearing assembly at a predetermined pressure.
Patent CA-2447786-A1 (CA)
Title: Mousse bioactive de nettoyage et de desencrage
Inventor: PIERCE RAYMOND JOHN
IPC: C11D1/83
Filed: 2002-05-16
Abstract: L'invention concerne un produit liquide aqueux moussant renfermant un liquide aqueux et un agent stabilisant, un tensioactif, une enzyme, et éventuellement un modificateur de viscosité et conservateur. Ce produit est exempt de solvants organiques et est particulièrement utilisé dans les industries de l'impression et des arts graphiques.
Patent CA-2448417-A1 (CA)
Inventor: MING-FU KUO
IPC: A63B53/04
Filed: 2003-11-05
Abstract: A putter comprises a shaft comprising an upper longitudinal groove; a T-shaped grip comprising a bar including a cavity with a first bearing fitted therein, an opposite, threaded projecting cylinder, and a longitudinal channel matingly engaged with the groove; an abutment assembly adapted to urge against a golfer's body and comprising a cylindrical projection having a peg fastened in the cavity; a sleeve including a recess and a nut; and a second bearing fitted in the recess wherein the cylinder passes the second bearing and the sleeve to theradedly secure to the nut; and a bifurcated head pivotably coupled to the shaft for permitting an angle adjustment therebetween. The invention enables even a novice to easily put the ball into the hole while playing since the hit ball tends to roll in a direction as expected.
Patent CA-2448836-A1 (CA)
Inventor: BELLIER ARNAUD
IPC: G01L27/00
Filed: 2003-11-07
Abstract: - Le dispositif (1) pour détecter la défaillance d'un capteur de pression (5 ) d'une centrale anémométrique (2) d'un aéronef comportant au moins deux capteurs de pression (5), comprend des moyens pour acquérir les valeurs de mesures réalisées par les capteurs de pression (5), des moyens pour calculer l'écart entre les valeurs ainsi mesurées, des moyens pour comparer cet écart à une valeur de seuil prédéterminée, et des moyens (13) pour afficher, si ledit écart est supérieur à ladite valeur de seuil, une information de défaillance de la centrale anémométrique (2) sur un dispositif de visualisation (15) qui est monté sur l'aéronef.</SD OAB>
Patent CA-2448851-A1 (CA)
Title: Nontobacco moist snuff composition
Inventor: CALANDRO DANIEL
IPC: A24B15/16
Filed: 2003-11-10
Abstract: \ The present invention provides a nontobacco or herbal moist snuff composition comprising an herbal component comprising, or consisting essentially of, corn silk. The present invention also provides a method of producing a nontobacco moist snuff composition having an herbal component comprising, or consisting essentially of, corn silk. Corn silk has a light texture, smooth mouth feel, uniform appearance, and a smell and taste that is nonexistent or easily disguisable. When corn silk is combined with a suitabl e casing component, the resulting nontobacco moist snuff composition has a light, elastic, and moist texture, a soft and smooth mouth feel, a uniform color an d particle size, and a long lasting and tobacco-like smell and taste with a characteristic tobacco-like "bite."
Patent CA-2449031-A1 (CA)
Title: Water-soluble porphyrin derivatives for photodynamic therapy, their use and manufacture
Inventor: YASHUNSKY DMITRI V
IPC: A61K31/409
Filed: 2002-05-31
Abstract: High purity pharmaceutical-grade water-soluble porphyrin derivatives having a general formula given by formula (1 or 2) and new methods to prepare and use such porphyrin derivatives: wherein B is a ring having the structure: (a) (b) (c) (d) (e) wherein : R1=-CH=CH2, -CH(Oalk)CH3, -CHO, -C(O)CH3, -CH2CH3, -CH(Alk)CH(COAlk)2, -CH2CH(COAlk)2, -CH(Alk)CH2COAlk, -CH(Alk)CH2CH(OH)CH3, and CH2CH2CH(OH)CH3 R2= -CH3, CHO, -CH(OH)Alk, CH=CHAlk, CH2OH, and CH2OAlk; R3= -OH, -Oalk, -NH-Alk, NH-X-COO-(HG)+, -NH-Y-NR8R9, -and NH-Y-OH; R4= -O-(HG)+, -Oalk, -NH-Alk, and NH-X-COO-(HG)+; R5= -O-(HG)+, -Oalk, -NH-Alk, and NH-X-COO-(HG)+; R6=H and COOAlk; R7=-O-(HG)+, -Oalk, -NH-Alk, and NH-X-COO-(HG)+; R8=H  and Alk R9=H and Alk wherein: -NH-X-COO-= the residue of organic amino acid; X  = alkylidene, peptides, oligopeptides and (CH2CH2O)nCH2CH2-, wherein n=1-30; Y  = alklidene and (CH2CH2O)nCH2CH2 -, wherein n1-30; G = a hydrophilic organic amine(CHf.ex. N-methyl-D-glucamine and other amino-group containing carbohydrate derivatives, TRIS, amino acids, oligopeptides); and Alk = an alkyl substituent. An embodiment of the present invention consists of a method to prepare water-soluble porphyrin derivatives comprising the steps of one- or two-step direct acidic alcoholysis of biological raw material producing a crystalline alkyl pheophorbide, conversion of the obtained alkyl pheophorbide into an acidic porphyrin, and reaction of the acidic porphyrin in water or in an aqueous organic solution with a hydrophilic organic amine. Another embodiment of the present invention consists of a method to prepare water-soluble porphyrin derivatives, comprising reaction of acidic porphyrins prepared by any known method in water or in aqueous organic solution with a hydrophilic organic amine. Another embodiment of the present invention comprises the additional step of purification of the resurtant water-soluble porphyrin derivative by reversed phase chromatography using volatile solvents.  The compound disclosed in the present invention can be used as photosensitizers for the photodynamic therapy of cancer, infectious and other diseases as well as for light irradiation treatment in other cases.
Patent CA-2449193-A1 (CA)
Inventor: LE PIOUFLE BRUNO
IPC: B01J19/00
Filed: 2001-06-08
Abstract: L'invention concerne un procédé de fabrication d'une structure microfluidique, en particulier une puce à ADN. Ledit procédé consiste à au moins : fabriquer un micro-moule tridimensionnel doté de moyens de définition d'une géométrie tridimensionnelle comportant au moins des micro-cupules et des micro-rainures ou des micro-canaux interconnectant lesdites micro-cupules et à utiliser uniquement ledit micro-moule afin de mouler une membrane composée d'un matériau polymérique. Ladite membrane comprend lesdites micro-cupules et lesdites micro-rainures ou micro-canaux, ladite membrane constituant une structure microfluidique.
Patent CA-2452530-A1 (CA)
Title: Novel immunosuppressive agent
Inventor: OHTA KEISUKE
IPC: A61K31/7032
Filed: 2001-07-09
Abstract: An immunosuppressive agent comprising, as an effective ingredient, at least one compound selected from the group consisting of compounds represented by general formula (1) below and pharmaceutically acceptable salts thereof:   (see formula 1) wherein R101 represents an acyl residue of a higher fatty acid, and R102 represents a hydrogen atom or acyl residue of a higher fatty acid.