baber/WOPTO huggingface dataset:
Patent WO-9011742-A2 (WO)
Inventor: HESSABI IRADJ
IPC: A61F5/01
Filed: 1990-04-06
Abstract: Un appareil pour améliorer la marche et la locomotion de personnes handicapées (2) comporte deux manchons (6, 14) qui se fixent sur les parties du corps (3, 4/3,5) des deux côtés de l'articulation (1), au moins un générateur de force se présentant sous la forme d'un ressort sous pression de gaz (7) et/ou d'un vérin hydraulique (8) actionnable manuellement, agencé entre les deux manchons (6, 14), et deux disques de support (10, 11/12, 13) interconnectés au niveau d'une articulation multipoints (9) et fixés chacun à un manchon (6, 14). Le générateur de force (7/8) est monté de manière articulée de chaque côté de l'articulation multipoints (9). Cet appareil pour améliorer la marche et la locomotion possède également un chariot (27) pourvu d'une plate-forme (28) et de quatre roues (29, 30). Les deux roues avant (29) sont fixées de manière excentrique sur un essieu commun (31) et sont mutuellement décalées de 180° dans leur position excentrique. Les deux roues arrière (30) sont chacune montées centralement sur leur propre essieu (32) et on peut faire varier télescopiquement la distance des roues arrière et de leur essieu (32) par rapport à l'essieu avant.
Patent WO-9600576-A2 (WO)
Title: Neue klinische anwendungen von polyen-makroliden
Inventor: STANKOV GEORGI
IPC: A61K9/00
Filed: 1995-06-28
Abstract: Die vorliegende Erfindung betrifft die Verwendung wenigstens eines Polyen-Makrolids zur Herstellung eines Arzneimittels zur Behandlung von Erkrankungen, die mit einer Störung des Energieumsatzes assoziiert sind. Insbesondere erlaubt die vorliegende Erfindung eine gezielte Stimulation der Energieumwandlung in menschlichen Zellen, d.h. eine Stimulation des Zellmetabolismus und damit die Behandlung von oder die Vorbeugung bei einer Reihe von Krankheiten.
Patent WO-9842497-A2 (WO)
Inventor: HERBRECHTSMEIER PETER
IPC: B29C35/08
Filed: 1998-03-23
Abstract: Procédés fiables et efficaces servant à fabriquer des moulages, en particulier, des lentilles ophtalmiques, telles que des lentilles de contact. Ces procédés présentent une série d'améliorations, y compris des améliorations concernant les conditions de coulage du prépolymère liquide dans des moules de lentilles, l'appariement des parties mâle et femelle du moule, la réutilisation des moules, la séparation des lentilles et des moules (démoulage), la manipulation des lentilles et l'inspection en ligne. L'invention également des séries cycliques d'étapes de traitement. Elle concerne, de plus, un outil de moulage amélioré comprenant une partie de moulage mâle et une partie de moulage femelle dans chacune desquelles est située une pluralité de moitiés de moules.
Patent WO-9939692-A2 (WO)
Inventor: CARLI FABIO
IPC: A61K47/14
Filed: 1999-02-05
Abstract: Process for the preparation of pharmaceutical compositions comprising one or more polymers and one or more drugs by the extrusion and spheronization technique, wherein said polymers belong to the group of the cross-linked amphiphilic polymers.
Patent WO-9942602-A2 (WO)
Title: Procede de preparation par fermentation de cytostatiques et de formes cristallines
Inventor: HOFMANN HANS
IPC: C12P/
Filed: 1999-02-17
Abstract: L'invention concerne un procédé permettant de concentrer des épothilones dans un milieu de culture, un procédé destiné à produire des épothilones, un procédé visant à séparer des épothilones A et B, et une souche obtenue par mutagenèse, conçue pour produire des épothilones. L'invention concerne également différents aspects liés à ces procédés, ainsi que des formes cristallines d'épothilone B.
Patent WO-0145515-A2 (WO)
Title: Procede de fabrication de viennoiseries telles que les croissants et autres produits semblables
Inventor: CEMELI DURAN MARC
IPC: A21D6/00
Filed: 2000-12-20
Abstract: L'invention concerne un procédé de fabrication de viennoiseries comprenant les étapes suivantes: pétrissage de la pâte, à base de farine de divers types possibles et d'additifs, en utilisant de la pectine; laminage de la pâte avec l'incorporation de matières grasses et la formation d'une pâte mince laminée; découpe de la pâte laminée en fragments et enroulement de ceux-ci; préfermentation, congélation entre -20 et -40° C, emballage et stockage des produits; et en temps voulu, désemballage et mise en place des produits sur des plateaux métalliques, cuisson à 180° C et refroidissement jusqu'à la température désirée. Ce procédé est utilisé dans la fabrication de viennoiseries, en particulier des croissants et autres produits semblables.
Patent ES-2054538-A2 (ES)
Title: Machine for shaping (profiling) a mitre in inner corners with radius for working in wood
Inventor: AGUAROD TOLOSANA ANTONIO
IPC: B27G5/04
Filed: 1991-10-23
Abstract: Machine which basically comprises two twin units arranged parallel to both sides of the imaginary line which passes through the mitre of the moulding to be produced, each one having a downward movement and another, horizontal- displacement movement for locating the cutting tool in the operational position, which tool is mounted on a horizontally displaceable tool holder, with reciprocating movement of both units which are duly synchronized and regulated. It makes it possible to cut a mitre in the rounded inner corner of the moulding.
Patent WO-9417969-A2 (WO)
Inventor: CASTRO GOMEZ LUIS
IPC: B28D1/06
Filed: 1994-02-01
Abstract: Les améliorations apportées à des machines et à des procédés de coupe de pierre consistent à modifier les anneaux (4), les tensionneurs (2), les châssis (3), les systèmes de tensionnement et autres pièces de la machine afin de tirer le meilleur parti de celle-ci et augmenter la vitesse d'avance. Le tensionnement hydraulique collectif est établi. On améliore l'utilisation des anneaux (4) et de la grenaille. On réduit les temps morts perdus pour changer les anneaux (4). On facilite le début et la fin de la coupe. On utilise un faible débit de boue par rainure de coupe. La boue est constituée de ferrite calcique. On fait en sorte que la boue adhère aux extrémités des anneaux (4) qui font saillie du bloc. La teneur en détritus de coupe dans la boue est limitée. Une machine économique, silencieuse et de grande production est obtenue.
Patent WO-0144467-A2 (WO)
Title: Method for obtaining human cdc25 phosphatases and method for identifying human cdc25 phosphatase modulators
Inventor: GOUBIN-GRAMATICA FRANCOISE
IPC: C07K19/00
Filed: 2000-12-13
Abstract: The invention concerns a  method for obtaining human cdc 25B1, cdc25B2, cdcB3 and cdc25C phosphatases. More particularly, the invention concerns a protein for fusion between human cdc25B1, cdc25B2, cdcB3 or cdc25C phosphatase and the maltose binding protein (MBP) of Escherichia coli, the DNA sequence coding for said fusion protein, a method for preparing said fusion protein and a method for identifying human cdc25B1, cdc25B2, cdcB3 or cdc25C protein modulators.
Patent WO-02062567-A2 (WO)
Title: Multilayer structure having a fluorinated polymer layer
Inventor: HIDALGO MANUEL
IPC: B32B27/08
Filed: 2002-02-05
Abstract: The invention concerns in a first embodiment a structure comprising successively: a first polyolefin layer, an optional binding layer, and a second fluorinated polymer layer. The binder layer may be based on hydrogenated three-block copolymer ABC, or may comprise several layers: an optional layer (L1) comprising a fluorinated polymer and a polymer essentially consisting of alkyl (meth)acrylate units, a layer (L2) based on polyamide with amine ends and a layer (L3) consisting of a polyolefin functionalised with an unsaturated carboxylic acid anhydride, the layer (L3) being in contact with the polyolefin layer. Said structures are useful for making devices for transporting and storing fluids.
Patent WO-2004028109-A2 (WO)
Title: System for transmitting a plurality of plesiochronous flows to a central processing unit
Inventor: LOSSOUARN YANN
IPC: H04J3/24
Filed: 2003-09-18
Abstract: The invention relates to a system for transmitting a plurality of  plesiochronous flows to a central processing unit, for instance, the flows transported by frames according to a bit-oriented protocol such as the HDLC protocol, wherein data flows F1 to Fn are processed in said central processing unit (4). The invention is characterized in that the system comprises a plurality of input circuits (11 to 1n) in which the inputs are provided to enable the reception of plesiochronous data flows (F1 to Fn) and a time multiplexer (2), wherein each of the inputs is connected to the output of an input circuit (11 ; i = 1 to n) and the output is located on a link (3) to said central processing unit (4), the input circuits (11 to 1n) being provided to align the plesiochronous data flows (F1 A Fn) on a same time basis and frequency.
Patent FR-2279173-A2 (FR)
Title: Anti-theft security system - has central transmitter receiver to interrogates peripheral transmitter receivers
IPC: G08B26/00
Filed: 1974-07-16
Abstract: The device forms part of a wireless security system, which is inviolable and which has permanent control of its operating state. The principal transmitter-receiver emits and transmits, by regular carrier waves, interrogation signals destined to interrogate peripheral transmitter-receivers which are the only ones able to receive these signals. The peripheral transmitter-receivers in their turn transmit to the principal transmitter-receivers by means of a carrier wave, response signals which only the principal transmitter receiver can receive. An alarm is triggered when the principal transmitter receiver does not receive the response signal from the peripheral-transmitter within a certain time.
Patent FR-2280753-A2 (FR)
Title: Metal structural element - is formed with holes passing through its thickness
IPC: E04B7/10
Filed: 1974-07-30
Abstract: The section can be of sheet metal, with the holes going right through it, over at least part of its surface being equidistantly spaced apart or not. The holes can be perforations made into a solid material before or after placing in position. The sections may be made of a prefabricated mesh of any type, such as expanded metal. Instead of these materials, rods or wires may be used and assembled together, for example by welding. The sections may be used for reinforcement in any molten material of a temperature compatible with the material of the sections. Alternatively, the section can be made from a moulded or cast material such as an asbestos-cement mixture.
Patent FR-2465108-A2 (FR)
Title: Dispositif a soupape pour la distribution de fluide sous pression
Inventor: BUDECKER LUDWIG
IPC: F15B13/06
Filed: 1980-08-20
Abstract: L'INVENTION CONCERNE UN DISPOSITIF A SOUPAPE POUR LA DISTRIBUTION DE FLUIDE SOUS PRESSION. CE DISPOSITIF COMPORTE UN RACCORD DE PRESSION 1 ET TROIS RACCORDS D'UTILISATEUR 2, 3, 4 DONT LE PREMIER EST RELIE A UN ACCUMULATEUR 7. LORSQUE L'ACCUMULATEUR EST CHARGE, C'EST CE DERNIER QUI SERA CHARGE D'ALIMENTER LE PREMIER ET LE TROISIEME RACCORDS D'UTILISATEURS 2, 4. LORSQUE L'ACCUMULATEUR EST DECHARGE, LE TROISIEME RACCORD D'UTILISATEUR 4 COMMUNIQUE PAR LE CLAPET 33 AU PREMIER RACCORD D'UTILISATEUR 2 QUI LUI-MEME EST RELIE A LA POMPE 6. L'INVENTION S'APPLIQUE A LA DISTRIBUTION DE FLUIDE SOUS PRESSION SUR UN VEHICULE AUTOMOBILE.
Patent FR-2466683-A2 (FR)
Title: Seal between piston and cylinder wall - uses set of rings in groove of one part tensioned against other part via ring groove spring
Inventor: STOLL KURT
IPC: F16J9/14
Filed: 1980-10-01
Abstract: The sealing device is used for the mutual seal between concentric parts which are movable axially relative to one another, and comprises a packet-shaped set of rings in a groove of the one part and which have a slot. This part is tensioned against the other part by a spring unit fitted on the base of the ring groove. The slot (12) in the sealing rings (8,9,10,11) is step-shaped. The seal is partic. suitable for fitment in the ring groove of the outer periphery of a piston or the inner periphery ring groove of a cylinder wall.
Patent FR-2527511-A2 (FR)
Title: Machine for briquetting sawdust with binder - employs two mixing chambers and automatic solids compaction and drying
IPC: B27N5/00
Filed: 1982-05-27
Abstract: Machine for forming compacted briquettes of sawdust held together by suitable glue or binding material employs two separate mixing chambers in sequence. The mixt. is withdrawn for briquetting from the second chamber only so that the first chamber is used to achieve thorough mixing. Binding material can be added as a liq. glue or as a solid; if the latter, any water necessary can be added in the form of moisture in the sawdust itself. Used for the prepn. of combustible briquettes from wood waste and sawdust.
Patent FR-2604850-A2 (FR)
Title: Plough bottom with symmetrical ploughshare and mouldboard
IPC: A01B61/04
Filed: 1986-10-13
Abstract: Plough bottom for a reversible plough according to the Claim of the main Patent, characterised in that it comprises a ploughshare 10 of special shape and two special deflectors 14/15, whose pivot pins 12 are carefully positioned with respect to the mouldboard 11.
Patent FR-2623379-A2 (FR)
Title: Improvement to a car tray
IPC: B60N3/00
Filed: 1987-11-23
Abstract: The invention relates to an improvement to a car tray, particularly designed for private cars, which attaches to the back of the front seat at the level of the support bars for the head restraint. The frame 6 supporting the tray has tiltable means of support 8 which have a device 11 for locking at a slope. This locking device 11 is formed from two symmetrical, toothed dishes 12 and 13 applied against each other using a screw 16 and nut 17. Each of the dishes 12 and 13 is integral respectively with the frame 6 and the vertical support rod 9. The invention relates to manufacturers of car accessories.
Patent WO-9831335-A2 (WO)
Title: Use of a serotonin antagonist and/or agonist respectively specific of the 5ht2 and 5ht1d receptor in a cosmetic or dermatological composition for sensitive skin and resulting composition
Inventor: BRETON LIONEL
IPC: A61Q5/10
Filed: 1998-01-14
Abstract: The invention concerns the use of an antagonist of serotonin specific of the 5HT2 receptor or of an agonist of serotonin specific of the 5HT1D receptor in a cosmetic composition or for preparing a dermatological composition for treating sensitive skin. It concerns in particular the use of an antagonist of serotonin specific of the 5HT2 receptor or of an agonist of serotonin specific of the human 5HT1D receptor for preventing and /or treating skin irritation and/or herpes and/or erythema and/or sensations of dysesthesia and /or inflammation and/or itching of the skin or for preparing a cosmetic or dermatological composition.
Patent WO-2004024762-A2 (WO)
Title: Proteine de type il-8
Inventor: FAGAN RICHARD JOSEPH
IPC: C12N15/24
Filed: 2003-09-12
Abstract: L'invention se rapporte à une nouvelle protéine, appelée INSP089, identifiée dans la description comme une protéine du type IL-8. L'invention se rapporte également à l'utilisation de cette protéine et d'une séquence d'acides nucléiques des gènes codants dans le diagnostic, la prévention et le traitement de maladies.
Patent WO-9401199-A2 (WO)
Title: Filter device for a stracheostoma
Inventor: SMITH RORY JAMES MAXWELL
IPC: A61F2/04
Filed: 1993-07-08
Abstract: A device for filtering air that is to be breathed through a tracheostoma, to simulate the role of the nose particularly in patients who have received a tracheostomy comprises a filter (20). The filter comprises a pre-filter (21) formed from electrostatically charged fibres, a first layer (22) formed from activated carbon and a second layer (23) a hydrophilic material such as one that is based on regenerated cellulose material. The filter includes a layer of adhesive by which it can be held in place when in use, and a cover layer (24) on its exposed surface.
Patent WO-9743437-A2 (WO)
Title: Inhibiteurs d'isopentenyle pyrophosphate isomerase (ipi) ou de prenyle transferase
Inventor: BROWN RICHARD JOHN
IPC: C12Q1/533
Filed: 1997-05-12
Abstract: Inhibiteurs soit de prényle transférase (farnésyle pyrophosphate synthase), soit d'isopentényle pyrophosphate isomérase, pouvant être mis en application dans différentes formes thérapeutiques et prophylactiques. L'invention concerne également l'utilisation de ces inhibiteurs dans le traitement de différentes maladies et de troubles du métabolisme osseux, ainsi que dans la recherche, l'isolement, la synthèse et l'évaluation de principes actifs ostéoactifs en tant qu'agents hypolipidémiques et anti-cancer.
Patent HR-P920564-A2 (HR)
Inventor: PALOSI ENDRE
IPC: C07D217/02
Filed: 1992-09-28
Abstract: Sadašnji izum odnosi se na tetrahidro-izokinolinske derivate opće formule (I):u kojoj su: R, R1, R2, R3 i R4 kao što je dato gore, raskida se zaštitna grupa u alkalnoj sredini.
Patent HU-0000271-A2 (HU)
Title: Use of glucagon-like peptide-1 (glp-1) or analogs to abolish catabolic changes after surgery
Inventor: EFENDIC SUAD
IPC: C07K14/605
Filed: 1997-08-26
Abstract: Method (A) for attenuating post-surgical catabolic changes and insulin resistance, comprises administering glucagon-like peptide-1 (GLP-1), a GLP-1 analogue, a GLP-1 derivative, or a salt of this compound. Also claimed are: (1) a method (B) for attenuating post-surgical catabolic changes and hormonal responses to stress, comprising administering a compound which exerts insulino-tropic activity by interacting with the same receptor (or receptors) with which GLP-1, GLP-1 analogues and GLP-1 derivatives interact in exerting their insulino-tropic activity, and (2) a method (C) for attenuating post-surgical catabolic changes and hormonal responses to stress, comprising administering a compound which enhances insulin sensitivity by interacting with the same receptor (or receptors) with which GLP-1, GLP-1 analogues and GLP-1 derivatives interact to enhance insulin sensitivity.
Patent HU-0001650-A2 (HU)
Title: Improved expression vectors
Inventor: HERMANSON GARY
IPC: C12N15/09
Filed: 1997-11-07
Abstract: The present invention provides isolated recombinant nucleic acid constructs comprising a dual bacterial promoter operably linked to a heterologous nucleic acid which encodes a desired polypeptide. The constructs are useful for the expression of the desired polypeptides in bacterial cells at high levels.
Patent HU-0002512-A2 (HU)
Title: Medicinal compositions for application to mucosa
Inventor: KAWABE HIROYUKI
IPC: A61K9/10
Filed: 1999-04-21
Abstract: Aqueous medicinal composition for application to the mucosa comprises a water insoluble or poorly water soluble substance and at least one pharmaceutical and has an osmotic pressure of less than 290 mOsm.
Patent HU-0003623-A2 (HU)
Inventor: METTLER HANS-PETER
IPC: C07C253/14
Filed: 1998-08-26
Abstract: A jelen találmány tárgyát az (I) általános képletű 1-(3-ciklopentiloxi-4-alkoxi-fenil)-4-oxo-ciklohexánkarbonitrilelőállítására szolgáló új eljárás képezi. Az (II) általános képletű 4-ciano-4-(3-ciklopentiloxi-4-alkoxi-fenil)-heptándisav-dialkil-észtertegy bázis jelenlétében a (III) általános képletű 5-ciano-5-(3-ciklopentiloxi-4-alkoxi-fenil)-2-oxo-ciklohexánkarbonsav-alkil-észterré ciklizálják, majd a (III) általános képletű vegyületet egyalkálifém-hidrogénkarbonáttal neutralizálják, majd egyalkálifémkarbonát jelenlétében dekarboxilálják, hogy megkapják az (I)általános képletű végterméket. Ó
Patent HU-0003730-A2 (HU)
Title: Use of gaba analogs such as gabapentin in the manufacture of a medicament for treating inflammatory diseases
Inventor: SCHRIER DENIS
IPC: A61K31/195
Filed: 1998-06-24
Abstract: GABA analogs such as gabapentin and pregabalin are useful to prevent and treat inflammatory diseases.
Patent HU-0102658-A2 (HU)
Title: Pharmaceutical composition containing opioid agonist and antagonist combination
Inventor: COLUCCI ROBERT D
IPC: A61K9/22
Filed: 1998-12-22
Abstract: The invention relates to oral dosage forms comprising a combination of an orally analgesically effective amount of an opioid agonist and an orally active opioid antagonist, the opioid antagonist being included in a ratio to the opioid agonist to provide a combination product which is analgesically effective when the combination is administered orally, but which is aversive in a physically dependent subject when administered at the same dose or at a higher dose than the usually prescribed dose of opioid agonist.
Patent HU-0104101-A2 (HU)
Inventor: TOTH LASZLO DR
IPC: G07C11/00
Filed: 2001-10-04
Abstract: Eljárás egy objektum azonosítására, amelynek során az objektumot azobjektum előre meghatározott, adatbázisban eltárolt azonosító jegyeialapján beazonosítják úgy, hogy az objektum jegyeit csoportosítottantartalmazó legalább egy paraméter és ismeret adatbázist hoznak létre;az objektum azonosítóelemeit előre meghatározott sorrend szerint,szintenkent (501, 502, 503, 504) csoportosítva megismerik; azokinformációértéket feldolgozzák, és a feldolgozás eredményefüggvényében az azonosítás eredményességét megállapítják, illetve azazonosítás eredménytelensége esetén az azonosítást és feldolgozást akövetkező szinten (502, 503, 504) elvégzik. Rendszer egy objektumazonosítására, amely legalább egy paraméter és ismeret adatbázisttartalmaz, és objektumazonosítási alrendszerből és mozgáskövetésialrendszerből van öszszeállítva, ahol az objektumazonosításialrendszer azonosítóelem-adatbázisból, felismerési módszeradatbázisból, azonosítási módszer adatbázisból van felépítve, és amozgáskövetési alrendszer ügyfél-azonosítási adatbázisból és ügyféladatbázisból van felépítve. Ó
Patent HU-0104157-A2 (HU)
Title: Roofing system
Inventor: KAEMPER JAN
IPC: E04D1/30
Filed: 2001-10-08
Abstract: Arrangement for laying roofing tiles, ridge tiles, or other roof covering parts (1) on roof battens in which the under side of the roof covering part facing the batten has a recess interacting with a spring clip (3) fixed to the batten is new. The recess is a groove which protrudes from the under side of the roof covering part. The spring clip has a bar (4) protruding in the direction of the recess and has a blocking piece (5) at one end. Preferred Features: The groove-like recess is formed in a material layer of the roof covering part.
Patent HU-0203050-A2 (HU)
Inventor: BOLOGNA WILLIAM J
IPC: A61K31/137
Filed: 2000-10-04
Abstract: A találmány endometriózis és meddőség kezelésére, valamint atermékenység fokozására alkalmas gyógyszerkészítményekre vonatkozik. Atalálmány szerinti gyógyszerkészítmények (i) gyógyászati szempontbólhatásos mennyiségben az endometriózis vagy a meddőség kezelésére,illetve a termékenység fokozására alkalmas b-adrenerg-agonistavegyületet, továbbá (ii) farmakológiai szempontból elfogadhatóbioadhéziós hordozóanyagot tartalmaznak. A találmány szerintigyógyszerkészítményt a hüvely nyálkahártyáján alkalmazva gyógykezelnilehet az endometriózist és a meddőséget, illetve fokozni lehet atermékenységet. Ó
Patent HU-0300205-A2 (HU)
Inventor: KEEN NICHOLAS JOHN
IPC: C07D401/12
Filed: 2000-09-19
Abstract: A találmány tárgyát az általános képletű vegyületek - ahol X oxigén-vagy kénatom, szulfinil-, szulfonil- vagy -NR6- általános képletűcsoport; R6 hidrogénatom vagy kis szénatomszámú alkilcsoport; R5 adottesetben szubsztituált, legalább egy nitrogénatomot tartalmazó aromásgyűrű; R1, R2, R3 és R4 halogénatom, ciano-, nitro-, alkil-tio-, -N(OH)R1 vagy R9X1- általános képletű csoport, amelyekben R7hidrogénatom vagy alkilcsoport; X1 különböző csoportokat jelent; és R9szubsztituált szénhidrogén-, heterociklil- vagy alkoxi-csoport; azzala fenntartással hogy R2vagy R3 közül legalább az egyiknek a jelentésehidrogénatomtól különböző - és sóik, észtereik, amidjaik vagyprodrogjaik és alkalmazásuk és ezeket tartalmazó gyógyszerkészítményekképezik. Ó
Patent HU-0301339-A2 (HU)
Title: Fused azepine derivatives and their use as antidiuretic agents
Inventor: ASHWORTH DOREEN MARY
IPC: C07D519/00
Filed: 2001-06-21
Abstract: Compounds according to general formulae (1 and 2), wherein G<SUP>1 </SUP>is an azepine derivative and G<SUP>2 </SUP>is a group according to general formulae (9-11) are new. Compounds according to the invention are vasopressin V<SUB>2 </SUB>receptor agonists. Pharmaceutical compositions of the compounds are useful as antidiuretic agents