baber/WOPTO huggingface dataset:
Patent CR-20160493-A (CR)
Title: Compuestos heteroaromáticos y su uso como ligandos de dopamina d1
Inventor: DAVORE JENNIFER ELIZABETH
IPC: C07D519/00
Filed: 2015-04-09
Abstract: La presente invención proporciona, en parte, compuestos de la Fórmula I: y las sales de estos aceptables desde el punto de vista farmacéutico; procesos para la preparación de; intermediarios usados en la preparación de; y composiciones que contiene estos compuestos o sales, y sus usos para tratar trastornos mediados por D1 (o asociados a D1) que incluyen, por ejemplo, esquizofrenia (por ejemplo, sus síntomas cognitivos y negativos), trastorno esquizotípico de la personalidad, deficiencia cognitiva (por ejemplo, deficiencia cognitiva asociada a esquizofrenia, AD, PD o tratamiento de farmacoterapia), ADHD, enfermedad de Parkinson, ansiedad y depresión.
Patent CR-20190121-A (CR)
Inventor: AZAPAGIC AZUR
IPC: A61M39/28
Filed: 2017-08-17
Abstract: Un equipo de administración para una bomba de infusión incluye un dispositivo de prevención de flujo libre con un émbolo móvil que incluye una superficie de leva que define un perfil irregular a lo largo de una dirección de movimiento del émbolo, en la forma del perfil de la superficie de la leva indica que el equipo de adminstración está autorizado para su uso con la bomba de infusión y puede indicar además el tipo específico de equipo de adminstración. Un sensor en la bomba de infusión detecta el movimiento del émbolo cuando una placa de la bomba de infusión se engancha y genera una señal de perfil en el dominio del tiempo que es representativa del perfil de la superficie de la leva. Un procesador evalúa la señal de perfil y controla el fuincionamiento de la bomba para proteger a un paciente de la carga inadecuada de un equipo de administración, el uso de un equipo de administración no autorizado y/o el uso de un tipo de equipo de administración no válido para un protocolo de infusión elegido.An administration set for an infusion pump includes a free-flow prevention device having a movable plunger that includes a cam surface defining an uneven profile along a direction of movement of the plunger, wherein the shape of the cam surface profile indicates the administration set is authorized for use with the infusion pump and may further indicate the specific type of administration set. A sensor in the infusion pump senses movement of the plunger as a platen of the infusion pump is latched and generates a profile signal in the time domain representative of the cam surface profile. A processor evaluates the profile signal and controls operation of the pump to protect a patient from improper loading of an administration set, use of an unauthorized administration set, and/or use of an invalid type of administration set for a chosen infusion protocol.
Patent CR-20190270-A (CR)
Title: Systems for providing an assembly line grow pod
Inventor: STOTT MARK GERALD
IPC: B65G43/02
Filed: 2018-06-04
Abstract: Systems and methods for providing an assembly line grow pod are provided. One embodiment of a grow pod includes an exterior enclosure that defines an environmentally enclosed volume, a track that that is shaped into a plurality of helical structures defining a path, and a cart that receives a plant and traverses the track. Some embodiments include a sensor for determining output of the plant, a plurality of environmental affecters that alter an environment of the environmentally enclosed volume to alter the output of the plant, and a pod computing device that stores a grow recipe that, when executed by a processor of the pod computing device, actuates at least one of the plurality of environmental affecters. In some embodiments, the grow recipe alters a planned actuation of the at least one of the plurality of environmental affecters in response to data from the sensor indicating a current output of the plant.Se proporcionan sistemas y métodos para proporcionar una canaleta de crecimiento de línea de montaje. Una modalidad de una canaleta de crecimiento incluye un encerramiento exterior que define un volumen ambientalmente encerrado, una pista que se forma en una pluralidad de estructuras helicoidales que forman una ruta, y un carro que recibe una planta y atraviesa la pista. Algunas modalidades incluyen un sensor para determinar el rendimiento de la planta, una pluralidad de afectadores ambientales que altera un medio ambiente del volumen ambientalmente encerrado para alterar el rendimiento de la planta, y un dispositivo de computación de canaleta que almacena una receta de crecimiento que, cuando se ejecuta por un procesador del dispositivo de computación de canaleta, acciona al menos uno de la pluralidad de afectadores ambientales. En algunas modalidades, la receta de crecimiento altera un accionamiento planeado de la al menos uno de la pluralidad de afectadores ambientales en respuesta a los datos del sensor que indican un rendimiento actual de la planta.
Patent CR-20210587-A (CR)
Title: SMALL MOLECULE INHIBITORS OF NF-kB INDUCING KINASE
Inventor: CHAI WENYING
IPC: C07D513/04
Filed: 2020-05-29
Abstract: The present invention relates to compounds that inhibit NIK and pharmaceutical compositions comprising such compounds and methods of using the same. These compounds and pharmaceutical compositions are envisaged to be useful for preventing or treating diseases such as cancer (such as B-cell malignancies including leukemias, lymphomas and myeloma), inflammatory disorders, autoimmune disorders, immunodermatologic disorders such as palmoplantar pustulosis and hidradenitis suppurativa, and metabolic disorders such as obesity and diabetes.
Patent CR-20210590-A (CR)
Title: Process for preparing xpo1 inhibitors and intermediates for use in the preparation of xp01 inhibitors
Inventor: AUSTAD BRIAN CLINTON
IPC: C07D403/12
Filed: 2020-05-01
Abstract: The present invention provides an improved process for preparation of the (Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylic acid (referred to as compound of the structural formula (III)), which is a useful key intermediate for the synthesis of Selinexor ((Z)-3-(3-(3,5-Bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyrazin-2-yl)acrylohydrazide). The process comprises reaction of the compound of the structural formula (I) (as described herein) with the compound of the structural formula (II) (as described herein) in the presence of a catalyst, an organic base and an ether-containing solvent. The subsequent hydrolysis of the formed compound of the structural formula (IIIa) (as described herein) is performed without isolation of the compound of the structural formula (IIIa), providing compound of the structural formula (III) in high yield and stereoselectivity.
Patent EC-SP003637-A (EC)
Title: Inhibidores triciclicos de poli (adp-ribosa) polimerasas
Inventor: SKALITZKY DONALD JAMES
IPC: C07D487/06
Filed: 2000-08-29
Abstract: Los compuestos de la fórmula mostrada abajo son inhibidores poli(ADP-ribosilo)transferase: Estos compuestos son útiles como terapéuticos en el tratamiento de cánceres y en el mejoramiento de los efectos de embolias cerebrales, traumas a la cabeza, y enfermedades neurodegenerativas.
Patent EC-SP045289-A (EC)
Title: Amidas sustituidas
IPC: C07D239/34
Filed: 2004-09-10
Abstract: Nuevos compuestos de la Fórmula estructural (I) son antagonistas y/o agonistas inversos del receptor de Canabinoide-1 (CB1) y son útiles en el tratamiento, prevención y supresión de enfermedades mediadas por el receptor CB1. Los compuestos de la presente Invención son útiles como drogas de acción central en el tratamiento de psicosis, déficits de memoria, desórdenes de reconocimiento, migraña, neuropatía, desórdenes neuro-inflamatorios incluyendo esclerosis múltiple y síndrome de GuillaEn-Barre, y secuelas inflamatorias de encefalitis viral, accidentes cerebrales vasculares, y traumatosis de cráneo, anomalías de ansiedad, stress, epilepsia, enfermedad de Parkinson, desórdenes en los movimientos y esquizofrenia. Los compuestos también son útiles para el tratamiento de desórdenes por abuso de sustancias, tratamiento de obesidad o desórdenes de obesidad, así como para el tratamiento de asma, estreñimiento, pseudo-obstrucción crónica intestinal, y cirrosis de hígado.
Patent EC-SP066364-A (EC)
Title: Moléculas de lubricina recombinantes y usos de las mismas
Inventor: FLANNERY CARL RALPH
IPC: A61B/
Filed: 2006-02-14
Abstract: Se describen moléculas de lubricina recombinantes y usos de las mismas. Se proporcionan nuevas moléculas de lubricina recombinantes y sus usos como lubricantes, agentes antiadhesivos y/o suplementos intra-articulares para, por ejemplo, articulaciones sinoviales, meniscos, tendones, peritoneo, pericardio y pleura.
Patent EC-SP099686-A (EC)
Title: Planta de tabaco mutagenizada como cultivo de semillas para la producción de aceite para usos energéticos, industriales y alimenticios
Inventor: FOGHER CORRADO
IPC: A23L33/00
Filed: 2009-10-12
Abstract: La presente invención se refiere al desarrollo de plantas de tabaco, modificadas mediante técnicas de mutagénesis, la hibridación interespecífica seguida de poliploidización y tecnologías del ADN recombinante, que se caracteriza por el hecho de ser capaz de producir una cantidad muy alta de semillas y su utilización para la producción de aceite para los ámbitos energético e industrial, tal como el aceite de combustión, biodiesel y aceite lubricante, y para la alimentación animal y humana.
Patent EC-SP941080-A (EC)
Title: Bi esters de metanediol con penicilinas de acido penicilianico 1.1 bioxido
Inventor: BIGHAM ERIC C
IPC: A61P31/04
Filed: 1994-05-05
Abstract: Este invento se refiere a nuevos compuestos químicos, más particularmente está relacionado con nuevos compuestos químicos que son de valor como agentes antibactericidas, son bi-esters de metaneidol, en el cual un grupo hidróxido de metanediol ha sido esterificado con el grupo hidróxido de metanediol ha sido esterificado (con el uso de esters) con el grupo carbóxido del ácido peniciliánico, (de penicilina).
Patent EC-SP941156-A (EC)
Title: 3 bencilaminometil piperidinas substituidas con heteroarilamino y heteroarilsulfonamido y compuestos afines
Inventor: HOWARD HARRY RALPH
IPC: C07D277/36
Filed: 1994-09-06
Abstract: La presente invención se refiere a nuevas 3-bencilaminometil-piperidinas sustituidas con heteroarilamino y heteroarilsulfonamido, a heteroarilsulfonamido, a heterociclos no aromáticos que contienen bencilamino nitrógeno substituído, a composiciones farmacéuticas que comprenden tales compuestos y el uso de tales compuestos en el tratamiento y prevención de trastornos inflamatorios y del sistema nervioso central, asi como otros varios trastornos. Los compuestos farmacéuticamente activos de esta invención son antagonistas del receptor de la substancia P. Esta invención se refiere también a nuevos intermedios empleados en la sintesis de tales antagonistas del receptor de substancia P.
Patent EC-SP951485-A (EC)
Title: Composicion fungicida que comprende una 2- imidazolina- 5 ona
Inventor: LATORSE MARIE PASCALE
IPC: C07D521/00
Filed: 1995-07-26
Abstract: Esta invención tiene por objeto una composición fungicida que comprende un compuesto de tipo 2-imidazolina-5-ona y un procedimiento que utiliza composición y destinado a proteger, con carácter curativo o preventivo, los cultivos contra los ataques fúngicos.
Patent EC-SP951599-A (EC)
Title: Sistema de aplicación de doble solucion
Inventor: HARRIS ROBERT D
Filed: 1995-12-01
Abstract: La presente invención se refiere a un aplicador de doble solución, en particular a un aplicador para limpiar textiles, el cual trae dos o más soluciones reactivas momentáneamente juntas antes de contactar el textil que está por limpiarse.
Patent EC-SP993160-A (EC)
Title: Acidos nucleicos y polipeptidos homologos il-17, vectores,celulas huesped, metodos y usos de los mismos
Inventor: GLASEBROOK ANDREW L
IPC: C12N15/19
Filed: 1999-09-29
Abstract: La presente invención se relaciona con por lo menos un polipéptido homólogo IL-17 nuevo, incluyendo ácidos nucleicos aislados que codifican por lo menos un polipéptido homologo IL-17 polipéptidos homólogos IL-17 vectores, células huesped, transgénicos, quiméricos y métodos para elaborar y usar los mismos, así como anticuerpos y métodos especificos de homólogos IL-17
Patent EE-9900350-A (EE)
Inventor: EIZO TAKAHASHI
IPC: E02D29/12
Filed: 1998-09-09
Abstract: According to the present invention, since an upper surface of a tread is formed of a horizontal portion extending from a central portion to side portions or inclined portions inclined downwardly from side portions or another inclined portions extending from both ends of the horizontal portion or the inclined portions at the angle ranging from 1 to 5 degrees, it enables operators to put their feet on a tread in a more natural state to move up and down under a stable condition, and to reduce their fatigue with their feet or knees when they move up and down in a manhole utilizing the foothold. To this end, in the foothold of the manhole the tread (5 or 23) and side portions (6 or 24) extending from and positioned at both sides of the tread (5 or 23), wherein at least an upper surface of the tread is formed of a horizontal portion (11) extending from a central portion (S) of the tread toward side portions thereof, inclined portions (27) inclined downwardly toward the side portions or inclined portions (12 or 28) inclined upwardly from both ends of the horizontal portion or both ends of the inclined portions (27) at an angle ranging from 1 to 5 degrees. <IMAGE>
Patent FI-20000368-A (FI)
Inventor: KOPSALA PANU
IPC: A61B6/06
Filed: 2000-02-18
Abstract: The invention relates to a method for imaging the head area by using a line detector camera (8) equipped with a digital detector, at which camera is directed an X-ray beam (11) through the object being imaged. In the method is used an apparatus (1) which makes possible the implementation of cephalometric imaging and at least one other imaging method, such as panoramic imaging. The apparatus comprises an X-ray source (5), a primary collimator (6) in conjunction with the X-ray source, a line detector camera (8), which is located to a position further away from the X-ray source (5) for implementing cephalometric imaging and/or to a position closer to the said X-ray source for the said other imaging method, and a secondary collimator (9) in the vicinity of the line detector camera (8) intended for cephalometric imaging. In the method, the radiation emitted from the X-ray source (5) is collimated in cephalometric imaging without turning the X-ray source in such a way that the ray beam (11) bypasses the position of the line detector camera (8) closer to the X-ray source (5).
Patent FI-20001601-A (FI)
Inventor: PERVAN TONY
IPC: E04F13/08
Filed: 2000-07-04
Abstract: The invention relates to a system for laying and mechanically joining building panels, especially thin, hard, floating floors. Adjacent joint edges (3, 4) of two panels (1, 2) engage each other to provide a first mechanical connection locking the joint edges (3,4 ) in a first direction (D1) perpendicular to the principal plane of the panels. In each joint, there is further provided a strip (6) which is integrated with one joint edge (3) and which projects behind the other joint edge (4). The strip (6) has an upwardly protruding locking element (8) engaging in a locking groove (14) in the rear side (16) of the other joint edge (4) to form a second mechanical connection locking the panels (1, 2) in a second direction (D2) parallel to the principal plane of the panels and at right angles to the joint. Both the first and the second mechanical connection allow mutual displacement of joined panels (1, 2) in the direction of the joint.
Patent FI-20030380-A (FI)
Inventor: HEIMALA SEPPO OLAVI
IPC: C22B3/04
Filed: 2003-03-14
Abstract: The invention relates to a method for controlling the partial pressure of oxygen when mutually separating minerals in the different process steps of the separation process. In order to control the partial pressure of oxygen, the gases fed in the different process steps are recirculated in an essentially closed gas circulation created around the equipment used in the different process steps, so that the gas recirculation is controlled by measuring the potential of the slurry containing valuable minerals.
Patent FI-20115822-A (FI)
Inventor: YLI-KOSKI ANTERO
IPC: G02B7/00
Filed: 2011-08-24
Abstract: An apparatus for optically measuring samples, including a radiation source configured to form an excitation beam in an excitation channel, a detector configured to detect an emission beam in an emission channel and a filter configured to be located, in an excitation position, in the excitation channel, and in an emission position, in the emission channel. The apparatus further includes a first filter storage comprising a first set of filter storage positions, a second filter storage comprising a second set of filter storage positions, and a filter transfer mechanism configured to move the filter between the excitation position, the emission position, the first set of filter storage positions and the second set of filter storage positions.
Patent FI-20175659-A (FI)
Title: Method of treating a fiber web and a treatment system for treatment of a fiber web
Inventor: ILOMÄKI JARI
IPC: D21G9/00
Filed: 2017-07-06
Abstract: The invention relates to a method of treating a fiber web, in which the fiber web (W) is calendered in at least one nip (N) of a calender (10), and before the calender (10) in running direction of the fiber web (W) one side of the fiber web or both sides of the fiber web is/are only surface dried in a surface drying zone (Z). The invention also relates to a treatment system for treatment of a fiber web comprising a calender (10) and before the calender (10) in running di-rection of the fiber web (W) located surface drying zone (Z), in which one side of the fiber web or both sides of the fiber web (W) is/are only surface dried.
Patent FR-1602763-A (FR)
Title: Plastic ultra-violet ray absorbing - coatings for glass
IPC: C09J7/22
Filed: 1968-12-31
Granted: 1971-01-25
Abstract: Damage by uv. rays, such as discoloration and ageing of articles exhibited behind windows and shop-windows, is prevented by applying a transparent, optionally coloured, sheet of polyester or other synthetic polymer, coated with an adhesive on the face to be applied to the inner glass surface, and containing uv. ray absorbing material and optionally heat-barrier and vapour-barrier material.
Patent GB-1051030-A (GB)
IPC: C08L9/00
Abstract: 1,051,030. Butadiene polymer-epoxy resin reaction products. K. NEY. Dec. 18, 1963, No. 49905/63. Headings C3B and C3P. Polybutadienes and/or butadiene-styrenes are reacted with an epoxy resinous material and a polyamine hardening agent. The reaction may take place at 30-40‹ or 60-90‹ C. There may also be present metals, or organic substances, e.g. wood or cork or natural or synthetic minerals. Specified amines are diethylamine or methylamine alone or in the presence of trimethylaminomethyl phenol. A specified epoxy resin has the formula
Patent GB-1051282-A (GB)
IPC: G09F3/10
Abstract: 1,051,282. Transfers. CHART-PAK Inc. March 26, 1965 [July 13, 1964; Dec. 31, 1964], No. 12895/65. Heading B6C. A transfer comprises an elongated transfer element 22 having a coating of pressure sensitive adhesive 24 on its underside, and a mask assembly 14 superposed on the upper surface of said element, the assembly having a central region of the same dimensions as the element and coated with a pressure-sensitive adhesive 36. The assembly is offset lengthwise with respect to the element so that one end 22A of the element contacts the adhesive 36 whereas the other end 22B is located beneath one of the non-adhesive end portions 32 of the assembly. A transparent strip 34 forms the upper surface of the assembly. The mask and transfer element may be removed together from a base material 12 having high release properties by lifting the right-hand side of the assembly 14, Figs. 3 and 4 (not shown). The transfer element is located in register on a receptor surface by holding the mask assembly and looking through the central region. The element is transferred by applying pressure to the said region and removing the mask assembly 14, Figs. 5 and 6 (not shown). The mask assembly may be replaced by a single transparent layer coated only in the central region of its lower surface with pressure sensitive adhesive or coated over all its lower surface and treated with a chemical to render the adhesive ineffective in areas outside said region. In a further embodiment, Figs. 9 and 10 (not shown), one end of the bottom surface of the transfer element is not adhered to the base surface so that the element may be used to transfer indicia etc. from one surface to another. The mask assembly may be extended laterally and provided with indexing holes for use in automatic machines.
Patent GB-1052714-A (GB)
IPC: B23K35/04
Abstract: 1,052,714. Welding by fusion. INSTITUT ELEKTROSVARKI IMENI E.O. PATONA. June 18, 1965, No. 25836/65. Heading B3R. An electrode for welding or surfacing comprises a metal ribbon 3 (not shown), folded with its edges inwards to form two concentric casings, the inner casing being formed of both side edges 1, 2 and housing a core 5 and the outer casing containing flux 4. The core 5 is of powdered metal or alloy for alloying and deoxidizing. The electrode may be a manual electrode or a continuous electrode. It may be used for welding steel. No external flux or gas shield is required.
Patent GB-1095425-A (GB)
IPC: B30B9/30
Abstract: 1,095,425. Packaging refuse; boxes; shoots. AUTO PAK CO. Feb. 23, 1965 [March 9, 1964], No. 7737/65. Headings B8C, B8P and B8S. A packer 10 at the bottom of a refuse shoot 16 of a multilevel building has an outlet opening 34 aligned with an inlet opening of a wheeled container 12 releasably connected to the packer for receipt of refuse, the container having projecting parallel bars for engagement by lifting elements of a self-loading vehicle 22 into which refuse, compacted in the container, is periodically emptied. Refuse, gravity fed into a hopper 20 is sensed by interruption of a light beam of a photo-electric control 160 which automatically energizes a pump motor supplying hydraulic fluid to a cylinder 66 to operate a reciprocating compaction blade 42 through levers and links 54, 90, the blade being retracted, to allow refuse to drop into the packer, and then advanced so that a ram surface 44 presses the refuse into the container, the operation continuing so long as refuse remains in the hopper. Hydraulic and electric circuits controlling the operation are described. A pressure responsive switch retracts the blade 42 if it encounters an obstruction and an alarm may be given. The shoot has access doors 18 at each level of the building and an access door in a housing for the packer so that refuse may be placed in the hopper. The container 12, mounted on swivellable wheels, has a hinged, latched lid for a top opening through which refuse is dumped into the vehicle 22, an upwardlly curving baffle to aid composition, and hooks for engagement with chains mounted on pivotable locking levers on the packer. A screen of stretched springs closes the inlet aperture of the container during travel to the vehicle. Entrance of refuse behind the packer blade is prevented by a pivoted baffle plate 60. In a modification the plate 60 is replaced by a pair of overlapping pivoted plates.
Patent GB-1107654-A (GB)
Abstract: 1,107,654. Toothed gearing; shaft couplings. POLYSIUS G.m.b.H. 18 March, 1966 [26 May, 1965], No. 11956/66. Headings F2Q and F2U. The drive to a double-helical gear 8 on the neck of a rotatable drum 1, e.g. a tube mill, comprises one or more drive motors 2 each driving a respective double-helical pinion 7 meshing with the gear 8 via two reduction stages 11, 12, one or both of which is/are planetary, located on axially opposite sides of the respective pinion 7 and connected by a torsionally flexible shaft 5 extending therethrough. The pinion 7 is secured on a hollow shaft 6, secured to the output of stage 12, through which the shaft 5 extends. A single motor 2 may be used, driving two or more parallel gear trains each including a flexible shaft 5 as above.