baber/WOPTO huggingface dataset:
Patent EA-018745-B1 (EA)
Title: Piping element and manufacturing a piping element
Inventor: JUUTI RAUNO
IPC: B29C48/11
Filed: 2008-05-22
Abstract: A piping element (1 ) comprises at least one flow pipe (4), an insulator (3) arranged outside it and a corrugated outer sheath (2) arranged outside the insulator (3) in such a way that the piping element (1 ) is bendable in its entirety. The outer diameter of the insulator (3) is reduced before conducting it to a corrugator (13) inside the outer sheath (2). In the corrugator (13), the insulator (3) reverts towards its larger outer diameter. The free outer diameter of the insulator layer is formed larger than the smallest inner diameter of the outer sheath (2).
Patent EA-017399-B1 (EA)
Title: Gas-liquid separator
Inventor: HOLTE SVERRE THOMAS
IPC: E21B43/12
Filed: 2008-02-06
Abstract: A gas-liquid separator (19) is disclosed, in particular for separating free water at a downhole position of a gas well. The separator (19) comprises a centrifugal separator (37) within a tubular portion (23) defining a gas inlet (27) and a gas outlet (29). Upstream of the centrifugal separator (37), the tubular portion (23) is provided with a plurality of drain holes (47) through which free water which was centrifugated to the tubular portion (23) enters an annular duct (33) allowing the collected water to flow off due to gravity. Upstream of the drain holes (47), a jet pump (51) is arranged. The jet pump (51) is driven by the gas stream to create underpressure in the duct (33) and to suck back gas which has entered the annular duct (33) through the drain holes (47). The gas-liquid separator (19) has no moving parts and avoids monitoring or controlling of the separating process.
Patent EA-016501-B1 (EA)
Title: Railway car bearing seal
Inventor: FETTY MARK W K
IPC: B61F15/22
Filed: 2011-04-15
Abstract: A bearing assembly is provided having a roller bearing with an inner raceway fitted around the journal portion of an axle. An outer raceway combines with the inner raceway to receive roller elements. An improved lubricant seal arrangement is provided between the wear ring and the supporting outer raceway comprising a slinger element.
Patent EA-019667-B1 (EA)
Title: Sub-cycle based aerosol disinfection system
Inventor: BERENTSVEIG VLADIMIR
IPC: A61L2/22
Filed: 2009-06-30
Abstract: A method of sterilising an object comprising the steps of i) placing an article to be sterilised in a sterilisation chamber; ii) providing a sterilising mist (for example hydrogen peroxide solution) to the sterilisation chamber, thereby to contact said article for a first duration; iii) providing a gas flow to said chamber for a second duration, thereby to displace, where present, said sterilising mist and to remove, where present, condensed mist from said article; wherein the total reduction in micro organisms over a time period encompassing the first duration and the second duration is less than log (6); and wherein steps ii) and iii) are repeated at least once to achieve a predetermined sterilisation parameter such as a predetermined sum total of contact time between the sterilising mist and the article, a predetermined sum total of sterilising mist provided to the sterilisation chamber or a predetermined level of sterilisation.
Patent EA-021126-B1 (EA)
Title: Substituted isoquinolinones and quinazolinones
Inventor: BERGHAUSEN JOERG
IPC: C07D417/12
Filed: 2010-12-21
Abstract: The invention relates to substituted nitrogen containing bicyclic heterocycles of the formula (I), wherein Z is CHor N-Rand X, R, R, R, R, Rand n are as defined in the description. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of MDM2 and/or MDM4, or variants thereof.
Patent EA-023436-B1 (EA)
Title: Method for geophysical survey
Inventor: YU ZHOU
IPC: G01V1/36
Filed: 2011-03-01
Abstract: There are provided herein a new system and method of local attribute match filtering which operate in the local attribute domain via the use of complex wavelet transform technology. This approach is adaptable to address various noise types in seismic data and, more particularly, is well suited to reduce the noise in geophone data as long as an associated hydrophone signal is relatively noise-free.
Patent EA-028836-B1 (EA)
Title: Natural extract from whole banana fruit (musa spp.)
Inventor: MEDASANI MUNISEKHAR
IPC: A61P9/12
Filed: 2010-08-11
Abstract: Provided is a natural extract from whole fruit of banana (Musa Spp.), whether unripe or ripe, containing mainly natural melatonin, serotonin, catecholamines and its precursors; amino acids tryptophan and tyrosine; minerals potassium, magnesium, phosphorous and antioxidants, and containing very minimal or no carbohydrates. Final extract is in liquid, semi solid or powder form. Extract is for animal use, in particular mammals, at doses 1 to 1,000 mg in powder or equivalent to powder per day. Extract is used as nutritional supplement or medicine in liquid, gel, capsule, caplet or tablet form. Physical treatment, enzymatic processes and resin extraction are mainly used for extraction. Food or pharmaceutical grade additives like preservatives or antioxidants are added to the extract for shelf life. Other extracts, vitamins, minerals and amino acids may be added for enhancement of the extract effectiveness. Extract is used for administering to animals for mood elevation, reducing stress, anxiety and depression; increasing Basal Metabolism Rate (BMR) and thermogenesis, and also for treating obesity, hyperlipidemia, hypercholesterol, hypertension, diabetes, sleeping disorders, neurological disorders, muscular disorders, erectile dysfunction and for increasing potassium content in the body.
Patent EA-024565-B1 (EA)
Title: Material handling tool
Inventor: COUTU TIMOTHY M
IPC: E01H5/02
Filed: 2010-08-17
Abstract: The present device is a tool for manipulating a material, such as snow, ice, sand, salt, dirt, gravel, concrete, vegetation, grains, debris and the like, resting on a surface. The tool includes an elongated handle, an elongated shaft, and a compound blade head. The handle is attached to a proximal end of the elongated shaft and the compound blade is fixed to a distal end of the elongated shaft. The tool is capable of pushing and pulling materials when operating either the first tool section or the second tool section. The compound blade head has a first tool section adapted generally for shoveling and digging and a second tool section adapted for chopping and scraping. Tamping, compressing, and leveling is achieved when using the tools in the shoveling/digging position. The structure of the tool is designed to endure the stresses and forces of aggressive and repeated operating.
Patent EA-022494-B1 (EA)
Title: Quinoline amide compounds which are muscarinic m1 receptor positive allosteric modulators
Inventor: KUDUK SCOTT D
IPC: A61K31/47
Filed: 2010-12-13
Abstract: The present invention is directed to quinoline amide compounds of formula (I)wherein all the substituents are disclosed in the claims, which are M1 receptor positive allosteric modulators and can be useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases mediated by the M1 receptor.
Patent EA-029729-B1 (EA)
Title: Apparatus and method for producing packaging
Inventor: KENN CHRISTOPH
IPC: B65B61/18
Filed: 2011-10-25
Abstract: Illustrated and described is an apparatus for producing packaging, in particular composite packaging for liquid foodstuffs, having a cross-sectional area that decreases in the pour-out direction in the gable region, composed of a jacket (1) having a gable region (2) having a plurality of gable faces (6) and of a pour-out element (4), wherein the apparatus has at least one rotatable mandrel wheel (15) having a plurality of mandrels (17) for holding the jackets. Additionally illustrated and described are a method for producing such packaging and a gable press for use with the abovementioned apparatus. In order to allow easier and more cost-effective production, it is proposed that the apparatus has a gable press (28), assigned to a single mandrel-wheel position, for folding the gable region, in order to connect all of the gable faces of the gable region of the jacket to the pour-out element and to seal the protruding ears (7) in the same mandrel-wheel position.
Patent EA-024677-B1 (EA)
Title: Touring or cross-country ski binding
Inventor: WOELLO EVEN
IPC: A63C9/086
Filed: 2011-09-15
Abstract: The present invention relates to a touring or cross-country binding comprising an engagement section (2.1) for pivotal engagement of a ski shoe engagement pin (21); a first housing section (9) provided with an opening (9.2) adapted to receive the engagement section (2.1); at least one resilient element (10) fastenable in front of the engagement section (2.1); and a second housing section (7) connected to the first housing section (9), wherein the resilient element (10) is provided with at least one rear flange (10.1) extending from a rear lower section of the element, wherein the at least one rear flange extends to a position under a bottom surface of the first housing section (9).
Patent EA-025344-B1 (EA)
Title: Adhesively bonded window and hardware assembly
Inventor: ACKERMAN MARK S
IPC: B60J1/00
Filed: 2011-10-14
Abstract: An adhesively bonded window and hardware assembly includes a window member (12) presenting a surface (12a), a hardware member (14) having a flange (14a) and a projecting portion (14b) contiguous with and projecting from the flange, an adhesive member (18) disposed between the flange and the surface of the window member and adhesively bonding the hardware member (14) to the window member (12), and a sealing member (20) that envelopes part o the flange, fully surrounds the adhesive member, and bonds to and seals against the surface of the window member. The sealing member (20) serves to protect the adhesive member (18) from heat and humidity in the surrounding environment. The sealing member (20) can comprise an overmolded member formed of a polymer material.
Patent EA-026477-B1 (EA)
Title: Handling device for drill rods and top drive with handling device
Inventor: MOSS JOHANNES
IPC: E21B19/06
Filed: 2012-11-19
Abstract: Claimed is a handling unit for drill rods having a tilt arm 34 and an elevator bracket 30, which can be pivoted under the influence of a tilt cylinder 32, and means for the detecting a position of the at least one elevator bracket 30. For detecting the position of one or each elevator bracket 30 at least one valve 50 is used and also a hydraulic switching control circuit 54 as a part of the handling unit, which continues outside the handling unit, and at least one connecting member 52, which can be moved by means of the tilt arm 34 and for which the at least one valve 50 is provided. One or each valve 50 opens the hydraulic switching control circuit 54 when the connecting member 52 is in a first position or location, and one or each valve 50 closes the hydraulic switching control circuit 54 when the connecting member 52 is in a second position or location. Thus, the state of the switching control circuit 54 can be evaluated as position information.
Patent EA-028791-B1 (EA)
Title: Crystalline form of an androgen receptor modulator
Inventor: SMITH NICHOLAS D
IPC: C07D401/04
Filed: 2013-06-04
Abstract: The present invention relates to a crystalline form B 4-[7-(6-cyano-5-trifluoromethylpyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-N-methylbenzamide that has (a) an X-ray powder diffraction (XRPD) pattern with characteristic peaks at 12.1±0.1° 2-Theta, 16.0±0.1° 2-Theta, 16.7±0.1° 2-Theta, 20.1±0.1° 2-Theta, 20.3±0.1° 2-Theta; (b) unit cell parameters substantially equal to the following at -173°C:and (c) a DSC thermogram with an endotherm having an onset temperature at about 194°C. Also described are pharmaceutical compositions comprising said crystalline form B for treating diseases or conditions that are associated with androgen receptor activity, in particular for treating prostate cancer in a mammal.
Patent EA-033170-B1 (EA)
Title: Method for gstm1 gene expression detection in samples of paraffin-fixed sections of mammary tumor tissue
Inventor: DEMIDCHIK YURY EVGENIEVICH
IPC: C12Q1/68
Filed: 2015-05-21
Abstract: The invention relates to medicine, in particular, to clinical laboratory diagnostics, and may be used for detecting the GSTM1 gene in samples of paraffin-fixed sections of mammary tumor tissue. The invention objective is to develop a method for detecting the GSTM1 gene expression in samples of paraffin-fixed sections of mammary tumor tissue, to provide the possibility of assessing the efficiency of the 2nd phase of xenobiotic biotransformation in the tumor cells (assessing the cells' ability of biochemically inactivating reactive xenobiotic metabolites). The objective is achieved as follows: human RNA is released from the paraffin-fixed sections of mammary tumor tissue, a reverse transcription reaction is conducted to obtain cDNA, which is then used for performing real-time TaqMan PCR with the use of matched pairs of primers and probes: for GSTM1 gene: forward-primer AAGTTGGCATGCCCATGATACTGG, reverse-primer CGTCCCCCATCGTGTACTTCTTTTC, TaqMan probe FAM-CCATCCGCCTGCTCCTGGAATA-BHQ1; for the reference gene HGUS: forward-primer CTCCAAGGAATTTTGCCGATT, reverse-primer GGCGTGAAGATCCGGTTTTTA, TaqMan probe JOE TGTTCAGTCACCGACAGTGCTG-BHQ2, the primers and the probes being introduced in a concentration of 3.2 pmol/μl, and then amplification is conducted according to the following programme: 1 cycle: 95°C - 5 min.; 50 cycles: 95°C - 20 s, 62°C - 20 s, 72°C - 15 s; 1 cycle: 72°C - 10 min, fluorescence detection is conducted at FAM and JOE channels; if the tested material has threshold cycle (Ct) values in the range of 0-20 cycles or 36-50 cycles for the JOE channel (reference gene HGUS), it is concluded that human cells are absent in the tested material and that GSTM1 gene expression cannot be assessed in the sample; if the tested material has Ct values in the range of 21-35 cycles for the JOE channel, it is concluded that human cells are present in the sample and then fluorescence data analysis is conducted for the channel FAM (gene GSTM1), if Ct values in the range of 21-35 cycles are determined for the FAM channel, a conclusion on the presence of GSTM1 gene expression is made, and if the tested material has Ct values in the range of 0-20 cycles or 36-50 cycles for the FAM channel, a conclusion is made on the absence of GSTM1 gene expression.
Patent EA-029485-B1 (EA)
Title: Methods of treating cancer selected from lymphoma, leukemia, myeloma, glioblastoma, colorectal cancer and hepatocellular carcinoma using 3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
Inventor: SCHAFER PETER H
IPC: A61K31/5377
Filed: 2013-08-08
Abstract: Provided herein is a method of treating cancer, which comprises administering to a patient 3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione, or an enantiomer or a mixture of enantiomers thereof, or a pharmaceutically acceptable salt thereof, wherein cancer is lymphoma, leukemia, myeloma, glioblastoma, colorectal cancer or hepatocellular carcinoma.
Patent EA-030271-B1 (EA)
Title: Aluminium smelter comprising a compensating electric circuit
Inventor: RENAUDIER STEEVE
IPC: C25C3/08
Filed: 2014-07-30
Abstract: This aluminium smelter comprises a line of cells (50) arranged transversely with respect to the length of the line, one of the cells (50) comprising an anode (52), riser and connecting electrical conductors (54) extending upwards along two opposite longitudinal edges of the cell (50) in order to conduct the electrolysis current to the anode (52), and a cathode (56) passed through by cathode conductors (55) connected to cathode leads connected to routing conductors for routing the electrolysis current to riser and connecting electrical conductors of the following cell (50). Furthermore, the aluminium smelter comprises a compensating electric circuit, different from the electric circuit travelled through by the electrolysis current, extending underneath the cells (50) and possibly being travelled through by a compensating current circulating under the cells (50) in the reverse direction to the overall circulation direction of the electrolysis current.
Patent EA-037738-B1 (EA)
Title: Crystal forms of glutaminase inhibitors
Inventor: STANTON TIMOTHY F
IPC: C07D417/14
Filed: 2015-08-07
Abstract: The invention relates to crystalline salts of a compound having the structure of formula (I), methods for their preparation, and related pharmaceutical compositions comprising the crystalline salt. The invention further relates to methods of treating or preventing cancer or an immunological or neurological disease comprising administering a crystalline salt of the invention.
Patent EA-035993-B1 (EA)
Title: Long-acting injectable formulations comprising an isoxazoline active agent, methods and uses thereof
Inventor: CADY SUSAN MANCINI
IPC: A61P33/14
Filed: 2016-02-26
Abstract: The invention relates to long-acting injectable formulations for combating parasites in animals, comprising at least one isoxazoline active agent, a poloxamer, and a co-solvent. The invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the long-acting injectable formulations of the invention to the animal in need thereof.
Patent EA-036411-B1 (EA)
Title: Feed additive of diacetophenonyl selenide and its application for treatment and prevention of selenium deficiency in animals
Inventor: VORONIN SERGEY PETROVICH
IPC: A23K10/00
Filed: 2018-05-15
Abstract: The invention relates to the field of feed production and concerns improvement of animal feed additives containing selenium. A feed additive of diacetophenonyl selenide for animals includes diacetophenonyl selenide, triacetin, expanded perlite in the following ratio, wt.%: diacetophenonyl selenide - 0.315-3.06; triacetin - 35.68-36.69; expanded perlite - the balance. The feed additive is used for the treatment and/or prevention of selenium deficiency in an animal. The invention also relates to a feed composition for animals comprising the feed additive. The feed additive ensures uniform distribution of selenium over the main feed with a large degree of dilution, the full use of selenium by the body of an animal or a bird, and protection of diacetophenonyl selenide from environmental factors.
Patent EA-037941-B1 (EA)
Title: RADIOLABELLED mGluR2/3 PET LIGANDS
Inventor: ANDRES-GIL JOSE IGNACIO
IPC: C07D487/04
Filed: 2016-12-16
Abstract: The invention relates to novel, radiolabeled mGluR2/3 ligands, selective versus other mGlu receptors which are useful for imaging and quantifying the metabotropic glutamate receptors mGlu2 and mGlu3 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a mammal, in vitro or in vivo and to precursors of said compounds.
Patent EA-036863-B1 (EA)
Title: Methanol synthesis from synthesis gases with hydrogen deficiency
Inventor: KOPETSCH HANS
IPC: C07C29/151
Filed: 2017-03-06
Abstract: The invention relates to a process and a plant for the methanol synthesis, in particular for the methanol synthesis from a synthesis gas which has a hydrogen deficiency. According to the invention, a purge gas stream therefor is branched off from the synthesis gas circuit of the methanol synthesis, liberated from methanol traces in a washing device, and then treated in a hydrogen separation device which comprises a membrane separation stage and a pressure swing adsorption stage. Depending on the application and magnitude of the hydrogen deficit the membrane separation stage and the pressure swing adsorption stage can be connected in series or in parallel.
Patent EA-035938-B1 (EA)
Title: Cleaning robot and method of surmounting obstacle
Inventor: HE YANG
IPC: G05D1/02
Filed: 2017-05-04
Abstract: The invention relates to the field of automatic cleaning technology, and specifically, to a cleaning robot (10) and a method of surmounting an obstacle. The method comprises, when a cleaning robot (10) moves, determining whether the cleaning robot (10) is blocked by an obstacle (501); and if so, controlling, according to a determination result, a first driving wheel (131) to surmount an obstacle first, and then a second driving wheel (132) to surmount the obstacle (502). The embodiment resolves a problem in which a cleaning robot is incapable of completing a cleaning task owing to being blocked by an obstacle, and can only continue the cleaning task with external assistance, thereby achieving the effect of independently completing surmounting an obstacle, and enhancing adaptability of the cleaning robot (10) to an environment.
Patent EA-039041-B1 (EA)
Title: Chromatography column qualification in manufacturing methods for produring anti-tnf antibody compositions
Inventor: RANDOLPH PAUL
Filed: 2019-04-19
Abstract: The invention relates to a method of operating a chromatography column in methods of manufacture for producing anti-TNF antibodies, e.g., the anti-TNF antibody SIMPONI (golimumab), and specific pharmaceutical compositions of the antibody. This method involves collecting column outlet signal and accumulated flow parameters at two or more intervals of at least one mobile phase transition front during operation of the chromatography column comprising column packing. A model gamma cumulative distribution curve is determined based on the collected column outlet signal and accumulated flow parameters for the at least one mobile phase transition front. The height equivalent theoretical plate (HETP) value is calculated for the at least one mobile phase transition front using parameters of the model gamma cumulative distribution curve and the quality of the chromatography column packing is assessed based on the calculated HETP value. If during routine column monitoring, an adverse trend in HETP is observed or the control limits are exceeded, the eluate product quality, column process performance, and/or impurity removal data should be evaluated to ensure product quality for the identified batch. Should any of the product quality or column performance fail the criteria set, appropriate corrective action, such as conditioning, repacking or replacing the column, and qualification should be performed prior to release for further use.
Patent ES-2169663-B1 (ES)
Title: Videoretrovisor interior para vehiculos.
Inventor: REYES INIGO VALERIANO
IPC: B60R1/02
Filed: 2000-05-09
Granted: 2003-11-01
Abstract: Videoretrovisor interior para vehículos. Tiene por objeto al mejorar la visión trasera del conductor o piloto en circunstancias en las que se dificulte ésta o sea imposible por los ocupantes, objetos o elementos opacos que la impidan o interfieran. Es un sistema de video compuesto por una cámara situada en la parte posterior del vehículo, que emite una señal de video, y que por medio de un cableado (canal) llega a la pantalla, con forma y apariencia según diseño deseado, para reproducir la señal y hacer las veces de retrovisor convencional.