baber/WOPTO huggingface dataset:
Patent CN-100516085-C (CN)
Inventor: YE JIANG
IPC: C07K1/14
Filed: 2007-07-06
Granted: 2009-07-22
Abstract: 本发明公开了一种提取蜈蚣酸性蛋白的方法，它包括有以下步骤：a.将蜈蚣细粉，加入无水乙醇脱脂，在冰水浴中超声波振荡，过滤；b.取滤渣，加入磷酸盐缓冲液，在冰水浴中超声波振荡，渗漉提取，渗漉液离心获取上清液，上清液过滤；c.将滤液置于半透膜中，浓缩透析留取浓缩液；用磷酸溶液调节浓缩液的pH值至偏酸性后，真空再次浓缩；d.将浓缩液加入无水乙醇至醇浓度达40～50%，离心获取半固体状沉淀，该沉淀用中性磷酸盐缓冲液溶解后，冷藏。本发明方法提取的蜈蚣酸性蛋白药理活性高。本发明同时公开了用本发明方法提取蜈蚣酸性在制备预防心力衰竭药物中的应用；在制备抑制心肌纤维化药物中的应用。在制备抑制心肌肥厚药物中的应用。
Patent CN-100493216-C (CN)
Inventor: ZHIHONG SUN
IPC: H04M3/51
Filed: 2007-04-03
Granted: 2009-05-27
Abstract: 本发明公开了一种本发明实施例提供一种集团总机的集团总机短信处理方法、集团总机的Portal服务器以及邮件服务器，用以解决现有集团短信查询时成功率较低的问题。本发明实施例通过将不可识别的非规定格式集团短信封装成邮件，发送到指定邮箱中，邮箱服务器通知短信坐席人工处理非规定格式的集团短信，从而为非规定格式的集团短信提供的一个完整处理流程，提高了响应集团总机短信的成功率，提升了集团成员对集团总机的满意度和感知度。
Patent CN-100539152-C (CN)
IPC: H01L27/092
Filed: 2007-03-16
Granted: 2009-09-09
Abstract: 本发明提供一种半导体结构及其形成方法，该方法以扩散地形程序(diffusion topography engineering，DTE)形成半导体结构。首先在半导体基板中形成沟槽隔离区以定义扩散区。在含氢环境下，对半导体基板进行DTE程序，且在扩散区上形成MOS元件。DTE程序造成硅迁移，形成圆形或T形的扩散区表面。此方法更可包括在进行DTE程序前，使扩散区的一部分形成凹陷。在DTE程序后，此扩散区形成倾斜表面。本发明能够改善各MOS元件内部的应力，从而提高元件的性能。
Patent CN-100507023-C (CN)
Inventor: YONGRUI WU
IPC: C21D1/26
Filed: 2007-08-15
Granted: 2009-07-01
Abstract: 一种冷硬钢带1/10硬度调质退火工艺，属金属热处理技术领域，用于解决冷硬钢带退火处理后如何达到高强度和高塑性的问题。特别之处是，所述方法包括一段升温至450℃±10℃；一段保温及吹扫；二段升温至500℃+10℃；二段保温及吹扫；冷却出炉等步骤。本发明方法可在冷轧氮氢和全氢罩式光亮退火炉上使用，适用于普碳钢、低碳钢和优质低碳素钢冷硬钢带调质退火。采用该工艺方法可消除钢带轧制加工内应力，提高钢带的塑性和韧性，达到钢带高强度和高塑性的使用要求。经检验，采用该方法加工的产品主要力学性能指标为：洛氏硬度(HRB)80-94；抗拉强度660-720MPa。此外，本发明还具有退火周期短，加工成本低等优点。
Patent CN-100549541-C (CN)
Title: 空调器
Inventor: WAN KIM CHI
IPC: F24F1/00
Filed: 2007-12-13
Granted: 2009-10-14
Abstract: 本发明公开了一种空调器，该空调器能够通过按钮触摸从按钮的前面发光并执行相应的操作。该空调器包括用于显示信息的显示部分，和按钮部分，该按钮部分中安装有多个按钮组件，以通过人体的接触来执行开关操作。每个按钮组件包括带电导体、用于发光的按钮LED，和用于限制由按钮LED产生的光的行进方向的引导件。
Patent CN-100480481-C (CN)
Title: 四角锥球面网壳无脚手架施工型钢托撑式吊装机具
Inventor: XIN ZHUO
IPC: E04G21/14
Filed: 2007-10-30
Granted: 2009-04-22
Abstract: 本发明公开了一种四角锥球面网壳无脚手架施工型钢托撑式吊装机具。首先在地面进行组件安装，每个组件均包括一个球和四根杆件，然后，用提升机具把组件提升起来，配合吊升就位并同时人工在上面进行“四杆连四球”施工安装。一圈与一圈安装叠加后，即构建成整个四角锥球面网壳。本发明的吊装机具为型钢托撑式拔杆，零件包括一根型钢、一根拔杆、两根带手拉葫芦或电动葫芦的缆风绳、一个滑轮、一个卷扬机及一根钢索、若干个螺栓。这些零件简单、轻便、价廉，而所组装起来的吊装机具却可以解决四角锥球面网壳重型构件的高净空安装难题。与传统施工方法相比较，本发明方法具有施工工效高、工期短、施工方便、安装质量优良率高、施工成本低的特点。
Patent CN-100533668-C (CN)
Inventor: LIFENG LIU
IPC: H01L21/266
Filed: 2008-09-16
Granted: 2009-08-26
Abstract: 本发明涉及一种半导体器件的离子注入方法，硅片放入离子注入内机，把具有网孔的丝网制成与硅片相同形状的阻挡网，阻挡网贴附在硅片表面，离子注入机向硅片表面注入离子，阻挡网的网丝阻挡了离子向硅片表面的注入，离子只能经阻挡网的网孔注入到硅片表面，在硅片表面形成网格状分布。本发明不用光刻胶制作，没有污染，操作简单，提高了生产效率，与光刻法具有相同效果，保持了半导体器件的优质特性。本发明由于阻挡网可以重复使用，减少了材料浪费，大大降低了半导体器件制造成本。
Patent PT-1151143-E (PT)
Title: Selection of proteins using rna-protein fusions
Inventor: SZOSTAK JACK W
IPC: C07K14/82
Filed: 2000-02-01
Abstract: Described herein are RNA-protein fusion production methods which involve a high salt post-translational incubation step.
Patent PT-1185387-E (PT)
Inventor: DAMASSE JEAN-MICHEL
IPC: C22C38/40
Filed: 2000-04-12
Abstract: The invention concerns a method for continuously casting an austenitic stainless steel strip with a thickness not more than 10 mm, directly from liquid metal, between two cooled horizontal rolls, characterised in that: said steel composition in weight proportions comprises: %C<=0.08%; %Si<=1; %P<=0.04; %Mn<=2; %Cr between 17 and 20; %Ni between 8 and 10.5; %S between 0.007 and 0.040; the rest being iron and the impurities resulting from preparation; the ratio Creq/Nieq ranges between 1.55 and 1.90 with: Creq(%)=%Cr+1.37 %Mo+1.5 %Si+2%Nb+3 %Ti; Nieq(%)=%Ni+0.31 %Mn+22 %C+14.2 %N+Cu; the surface of the rolls comprises contiguous dimples with more or less circular or elliptical cross-section, of diameter between 100 and 1500 mum and depth between 20 and 150 mum; the inerting gas surrounding the meniscus is a gas soluble in steel or a mixture of such gases, or consists of at least 50% by volume of such a gas or mixture of gases.
Patent PT-1194415-E (PT)
Inventor: SIMIG GYULA
IPC: C07D239/46
Filed: 2000-06-29
Abstract: Piperazinylalkylthiopyrimidine derivatives of formula (I), a process for preparing them, and pharmaceutical compositions containing them as active substances. The compounds are useful for the treatment of central nervous system disorders, especially anxiety.
Patent PT-1220830-E (PT)
Title: Use of elastase for opening obstructed arteries and veins
Inventor: FRANANO NICHOLAS F
IPC: A61K38/46
Filed: 2000-09-24
Abstract: The invention provides methods to treating an obstructed biological conduit, that include administering to the conduit an agent that can degrade extracellular matrix of obstructing tissue. Particular methods include delivery of an enzyme or a mixture of several enzymes to the area or region of obstruction wherein the enzyme(s) have the capability to degrade extracellular matrix components within the obstruction thereby restoring the normal flow of transported fluid through the conduit. The invention also includes preventively dilating a section of conduit to minimize the risk of obstruction formation.
Patent PT-1226078-E (PT)
Inventor: BYRNE CHARLES MICHAEL
IPC: A23F5/24
Filed: 2000-11-03
Abstract: A container contains coffee, tea or a soft drink saturated with an inert gas and, if necessary or desired, a foam-retaining agent. Alternatively, a bulk container includes coffee, tea or a soft drink and, if necessary or desired, a foam-retaining agent, in association with means for dispensing the soft drink, and means for introducing an inert gas on dispensing. <??>By means of the invention, a non-alcoholic drink is dispensed with a creamy head.
Patent PT-1110551-E (PT)
Inventor: YANAGISAWA HIROAKI
IPC: A61K31/41
Filed: 1995-03-16
Abstract: Use, in the manufacture of a medicament suitable for local application to the eyes for use in combination with a  beta -blocker for the treatment of ocular hypertension and/or glaucoma, of a compound of general formula (I): <CHEM>  wherein:   R<1> represents alkyl, alkenyl or a group of formula R<5>-A-B- (R<5> represents hydrogen, alkyl, cycloalkyl or aliphatic acyl, A represents oxygen or sulfur, and B represents a single bond or alkylene); R<2> represents alkyl, alkenyl or a group of formula -C(R<6>)(R<7>)(R<8>) (R<6> represents hydroxyl or alkoxy, and R<7> and R<8> represent hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, aryl or aralkyl); R<3> represents carboxyl or a group of formula -CON(R<9>)(R<10>) (R<9> and R<10> represent hydrogen or alkyl optionally substituted by 1 to 3 substituents from Substituent group (I)); and optionally substituted by 1 to 3 substituents from Substituent group (I)); and   R<4> represents carboxyl, carboxycarbonyl or tetrazol-5-yl; substituent group (I): aryl, 5- or 6-membered heteroaromatic ring group, halogen, hydroxyl, alkoxy, carboxyl, alkoxycarbonyl, amino, aliphatic acylamide and aromatic acylamide.
Patent PT-1412514-E (PT)
Title: Enzymatic process for the preparation of substituted carboxylic esters
Inventor: STUTZ STEFAN
IPC: C07C69/533
Filed: 2002-04-26
Abstract: A process for the preparation of 2(S)-alkyl-5-halogenpent-4-ene carboxylic esters by enzymatic hydrolysis, comprising the steps: a) enzymatic hydrolysis of racemic 2-alkyl-5-halogenpent-4-ene carboxylic esters in aqueous and alkaline medium in the presence of an esterase; b) isolation of 2(S)alkyl-5-halogenpent-4-ene carboxylic esters by extraction with an organic solvent; c) isolation of 2(R)-alkyl-5-halogenpent-4-ene carboxylic acids from the aqueous-alkaline medium; d) Esterification of 2(R)-alkyl-5-halogenpent-4-ene carboxylic acids, e) subsequent racemization to form 2-alkyl-5-halogenpent-4-ene carboxylic esters; and f) return of the racemate obtained in step e) to step a), if necessary together with fresh racemic 2-alkyl-5-halogenpent-4-ene carboxylic esters. The process permits the undesired R-stereoisomers to be converted into the desired 2(S)-alkyl-5-halogenpent-4-ene carboxylic esters to avoid waste product from the synthesis.
Patent PT-1453962-E (PT)
Title: Inhibitor oligonucleotides and their use for specific repression of a gene encoding an androgen receptor
Inventor: HAREL-BELLAN ANNICK
IPC: A61K48/00
Filed: 2002-11-08
Abstract: Double-stranded oligonucleotides (I) consisting of two complementary strands (Ia; Ib), each having at one of their 3' and 5' ends 1-5 unpaired nucleotides, forming single-stranded overhangs, are new. One of (Ia) and (Ib) is complementary to a target sequence, of DNA or RNA, that is to be specifically repressed. ACTIVITY : Cytostatic; Virucide; Anti-HIV; Neuroprotective; Ophthalmological; Antidiabetic; Antipsoriatic; Antirheumatic; Antiarthritic. The oligonucleotide hybrid (A) prepared from sequences of formulae ggggaggcagccauugagacTT gucucaauggcugccuccccTT (lower case indicates ribonucleotides and upper case deoxyribonucleotides) was designed to target the junction of the PML/RARalpha fusion gene associated with promyelocytic leukemia. It (500 ng) was introduced into NIH 3T3 cells, co-transfected with a vector (100 ng) that expressed the PML/RARalpha fusion. Western blotting analysis after 48 hours showed greatly reduced expression of the fusion protein, relative to a control without (A). MECHANISM OF ACTION : Antisense inhibition of gene expression.
Patent PT-1585887-E (PT)
Title: Hydraulic or pneumatic machine with tilting blades
Inventor: HOLT CORNELIU
IPC: F01C3/02
Filed: 2002-12-12
Abstract: This invention refers to a hydraulic or pneumatic machine with tilting blades, running either as an engine on a fluid flow or on pressure fluid or as a pump or a compressor. The hydraulic or pneumatic machine on a fluid flow according to the invention consists of a cylindrical casing with inlet and outlet openings, radially arranged, diametrically oposed, along the fluid flowing direction, some disk like rotors with tilting blades, hinged over their front faces and provided with driving mechanisms of their own, and some fixed drums located between the rotors, concentrically to them, making inside the machine some channels, symetrically arranged on one or several stages. Flowing through the channels, the fluid drives the tilting blades causing the movement of the rotors, all the rotors moving to one sense being coupled to the same outlet shaft of the machine. The tilting blades of the hydraulic or pneumatic machine operating according to the invention with pressure fluid, run in variable depth grooves located in the rings between the front faces of the rotors and connected to the fluid circuit, the operation conditions of the machine-motor or pump-being determined by the moving sense of the blade in the groove.
Patent PT-1526856-E (PT)
Title: Pharmaceutical composition comprising estetrol derivatives for use in cancer therapy
Inventor: BENNINK HERMAN JAN TIJMEN COELINGH
IPC: A61K45/06
Filed: 2003-07-11
Abstract: Other aspects of the invention relate to pharmaceutical compositions, drug delivery systems and kits comprising the aforementioned estrogenic component in combination with an estrogen suppressant.
Patent PT-1575969-E (PT)
Inventor: SC NEDJELJKO KUJUNDZIC D
IPC: C07H17/08
Filed: 2003-11-10
Abstract: The invention relates to substituted 9a-N-{N'-[4-(sulfonyl)phenyl]carbamoyl} derivatives of 9-deoxo-9-dihydro-9a-aza-9a-homoerithromycin A and 5-0-desosaminyl-9-deoxo-9-di-hydro-9a-aza-9a-homoerithronolide A, novel semisynthetic macrolide antibiotics of the azalide series general formula (1), wherein R represents H or cladinosyl moiety and R1 represents chloro, amino, phenylamino, 2-pyridylamino, 3,4-dimethyl-4-isoxalylamino and 5-methyl-3-isoxazolylamino group, and pharmaceutically acceptable addition salts thereof with inorganic or organic acids. to the process for their preparation of pharmaceutical composition as well as the use their compositions for sterilization rooms and medical instruments as well as for protection of wall and wooden coatings
Patent PT-1508749-E (PT)
Title: Operating mechanism for kitchen range hood
Inventor: HEDMAN PER-MARTIN
IPC: F24C15/20
Filed: 2004-08-18
Abstract: The invention relates to a kitchen range ventilation arrangement comprising a valve (4) which is designed to regulate an air flow from a kitchen range hood (2) to an outlet duct (3) and which comprises a valve flap (5) which is p ivoted about a first axis of rotation (6), the kitchen range ventilation arrangement moreover comprising an operating device (7) for operation of the valve flap (5). A transmission device (6, 12, 13, 14, 15, 16) connected to the valve flap (5) and the oper ating device (7) is designed such that a swivel movement of the operating device (7) is matched by a swivel movement of the valve flap (5), the swivel movement of the valve flap (5) being of a different magnitude to the swivel movement of the operating device (7).
Patent PT-1518538-E (PT)
Title: Cosmetic composition in aerosol form comprising the association of a water-dispersible sulfopolyester and of a non-associative polyurethane
Inventor: PATAUT FRANCOISE
IPC: A61K8/85
Filed: 2004-09-27
Abstract: Aqueous composition for cosmetic treatment of keratinic materials comprises a water-dispersible sulfo polyester and a polyurethane, where either the sulfo polyester is derived from isophthalic acid, sulfoisophthalic acid and diethylene glycol or the polyurethane is water-soluble. An independent claim is also included for an aerosol device comprising a composition as above and a propellant.
Patent PT-1696905-E (PT)
Title: Substituted 2-aminotetralines for the preventive treatment of parkinson`s disease
Inventor: FRANK DRESSEN DR
IPC: A61P25/16
Filed: 2004-12-23
Abstract: The invention relates to the use of substituted 2-aminotetralins of general formula (I) as a medicament for the preventive treatment of Parkinson's disease.
Patent PT-1701721-E (PT)
Title: Use of pilocarpine for hypoptyalism treatment
Inventor: PEROVITCH PHILIPPE
IPC: A61K9/00
Filed: 2005-01-07
Abstract: Composition comprises pilocarpine and a bioadhesive polymer for local adhesion to buccopharyngeal tissue. ACTIVITY : None given. MECHANISM OF ACTION : None given.
Patent PT-1919896-E (PT)
Title: Aminoaryl sulphonamide derivatives as functional 5-ht6 ligands.
Inventor: JASTI VENKATESWARLU
IPC: A61K31/4523
Filed: 2005-10-26
Abstract: The present invention provides aminoaryl sulphonamide derivatives of formula (I), useful in the treatment of a CNS disorder related to or affected by the 5-HT6 receptor. Pharmacological profiles of these components include high affinity binding with 5-HT6 receptors along with good selectivity towards the receptor. The present invention also includes stereoisomers, the salts, methods of preparation and medicine containing the aminoaryl sulphonamide derivatives.
Patent PT-2134712-E (PT)
Title: Aspartate of 1-cyclopropyl-6-fluoro-7-(8-methoxyimino-2,6-diaza- spiro [3.4]oct-6-yl)-4-oxo-1,4-dihydro-[1,8] naphthyridine-3-carboxylic acid, method for preparing the same, and antimicrobial pharmaceutical composition comprising the same
Inventor: RYU JEI MAN
IPC: A61K31/47
Filed: 2008-04-14
Abstract: Disclosed are aspartic acid salts of 1-cyclopropyl-6-fluoro-7-(8-methoxyimino-2,6-diaza-spiro[3.4]oct-6-yl)-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid, methods for preparing the same, and antimicrobial pharmaceutical compositions comprising the same.
Patent PT-2173413-E (PT)
Title: Injection device
Inventor: JENNINGS DOUGLAS IVAN
IPC: A61M5/20
Filed: 2008-07-28
Abstract: An injection device comprises a locking mechanism between a syringe carrier (127, figure 3) and a drive mechanism (129, figure 3) of the injection device. The syringe carrier is connected to a latch actuator 137a from which locking arms 171 extend to engage a locking surface 172 on the drive mechanism, such that the syringe carrier can not be moved forward without corresponding forward motion of the drive mechanism. The drive is secured in place by a locking trigger arrangement (102, figure 2a) which bears on the housing of the device. Only when the trigger is released can the drive operate and so move the syringe carrier into its operational position.
Patent PT-2252643-E (PT)
Title: Dryer configuration for production of polyester particles
Inventor: DEBRUIN BRUCE ROGER
IPC: B29B9/16
Filed: 2009-03-03
Abstract: A process for producing non-solid-stated polyester polymer particles having one or more properties similar to polyester polymer particles that have undergone solid-state processing. In one embodiment, the process comprises (a) forming polyester polymer particles from a polyester polymer melt; (b) quenching at least a portion of the particles, (c) drying at least a portion of the particles, (d) crystallizing at least a portion of the particles, (e) annealing at least a portion of the particles. At all points during and between steps (b) through (e), the average bulk temperature of the particles is maintained above 165° C.
Patent PT-2307420-E (PT)
Title: Nalmefene di-ester prodrugs
Inventor: GUILLAUME MICHEL JOSEPH MAURICE ANDRE
IPC: A61K31/485
Filed: 2009-04-23
Abstract: The present invention relates to prodrugs of nalmefene of formula (I), pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment of substance abuse disorders such as alcohol abuse and alcohol dependence and impulse control disorders such as pathological gambling and addiction to shopping.
Patent PT-2364691-E (PT)
Title: Vegf antagonist formulations suitable for intravitreal administration
Inventor: GRAHAM KENNETH S
IPC: A61K9/00
Filed: 2007-06-14
Abstract: Ophthalmic formulations of a vascular endothelial growth factor (VEGF)-specific fusion protein antagonist are provided suitable for intravitreal administration to the eye. The ophthalmic formulations include a stable liquid formulation and a lyophilizable formulation. Preferably, the protein antagonist has the amino acid sequence showing in SEQ ID No: 4 or amino acids 27-457 of SEQ ID No: 4.
Patent PT-586167-E (PT)
Inventor: CHABRAND CHRISTINE JACQUELINE
IPC: C08F4/44
Filed: 1993-08-23
Abstract: Novel metallocene complexes are disclosed comprising polmerisable olefinic groups for example vinyl. The complexes may be combined with activators such as methyl aluminoxane for the polymerisation of olefins.
Patent PT-660873-E (PT)
Inventor: VEGA JOSE LUIS
IPC: C11D17/06
Filed: 1993-08-30
Abstract: A process in which the bulk density of a particulate detergent material is increased starting from an initial bulk density of at least 600 g/l, by spraying a liquid onto the particles and dusting with a fine powder in one or more rotating drum(s) or mixer(s), characterised in that the particulate detergent material initially has a mean particle size greater than 400 micrometers, and that the increase in the mean particle size during the process is not greater than 60 %. The invention also discloses a detergent composition having excellent dispensing and dissolving properties.
Patent PT-676597-E (PT)
Inventor: FERROLI DANTE
IPC: F24H9/00
Filed: 1995-03-06
Abstract: The present invention relates to a pipe assembly for conveying fumes in steel boilers provided with condensate quick evaporating means, characterized in that it comprises an inner pipe (2) and an outer pipe (3) which define a closed gap (4) therebetween. The main feature of the invention is that between the inner pipe (3) and outer pipe (4) are provided contacting lines extending according to parallel lines which are either helicoidal or not.
Patent PT-820390-E (PT)
Inventor: TAILLE OLIVIER DE LA
IPC: B60R5/04
Filed: 1996-04-05
Abstract: PCT No. PCT/FR96/00525 Sec. 371 Date Jan. 21, 1998 Sec. 102(e) Date Jan. 21, 1998 PCT Filed Apr. 5, 1996 PCT Pub. No. WO96/32301 PCT Pub. Date Oct. 17, 1996A removable rear shelf for a motor vehicle and lateral supports therefor. The shelf includes a pair of front corners and an abutment surface adjacent the front corners on the bottom surface of the shelf. Each of the lateral supports includes a surface on which the bottom surface of the shelf rests when installed in the motor vehicle, a coupling element which receives a front corner of the shelf and permits rotation of the shelf relative to the supports for installation and removal, and an abutment surface which is complementary with the abutment surface on the shelf to prevent rearward movement of the shelf when installed.
Patent PT-855972-E (PT)
Inventor: ALLISON GREGORY P
IPC: B60R7/02
Filed: 1996-10-17
Abstract: An interlocking arrangement of storage boxes in the rear section of a passenger vehicle such as a sport utility vehicle. The arrangement preferably includes at least three storage boxes. Two of the boxes are respectively secured to the side walls of the vehicle. These side boxes are spaced from each other and the third box is slidably receivable between them. In the preferred embodiment, the third box has lips on its sides that respectively interlock with lips on the two side boxes to prevent the third box from being removed by lifting it upwardly between the two side boxes. Forward stops on the side boxes prevent the third box from being moved forwardly beyond the side boxes and the vehicle's tailgate in its closed position serves to prevent the third box from being moved rearwardly out of the vehicle. In this manner and with the tailgate in its locked, closed position, the three interlocking storage boxes are securely held in place.
Patent PT-804449-E (PT)
Inventor: FOUACHE CATHERINE
IPC: C07H15/04
Filed: 1996-11-14
Abstract: A novel method for making palatinitol comprising a first step of epimerising isomaltose under conditions enabling a mixture of alpha-D-glucopyranosyl-(1->6)-D-mannose and isomaltose to be achieved, a second step of catalytically hydrogenating the mixture, and a third step of chromatographically depleting the isomaltitol in the hydrogenated mixture to give a roughly equimolecular mixture of alpha-D-glucopyranosyl-(1->6)-D-sorbitol and alpha-D-glucopyranosyl-(1->6)-D-mannitol.
Patent PT-837525-E (PT)
Inventor: GERKE DIETER
IPC: H01R4/24
Filed: 1997-07-09
Abstract: The connector element has cutting clamp contacts (4) in the chamber (17) of a holder part for uninsulated connection of electrical conductors. A sliding part (1) has a bore for holding the conductor inserted into it at an angle and encloses part of the contact in the chamber. The bore in the slider is at an angle to the longitudinal axis of the slider, which coincides with that of the chamber. The conductor is fed on both sides of the cutting clamp contact in the bore. The contact is mounted at an angle to the front wall of the chamber.
Patent PT-915899-E (PT)
Inventor: RILEY DAVID A
IPC: C07H17/08
Filed: 1997-07-28
Abstract: Preparation of 6-O-methylerythromycin A crystal form II comprising: (a) converting erythromycin A to 6-O-methylerythromycin A; (b) treating 6-O-methylerythromycin A with a solvent selected from (i) an 1-5C alkanol (except ethanol or isopropanol), (ii) a 5-12C hydrocarbon, (iii) a 3-12C ketone, (iv) a 3-12C carboxylic ester (except isopropyl acetate), (v) a 4-10C ether, (vi) benzene (optionally substituted by one or more substituents selected from 1-4C alkyl, 1-4C alkoxy, nitro or halo), (vii) a polar aprotic solvent, (viii) a compound of formula HNR1R2 where R1, R2 = H or 1-4C alkyl (provided that R1 and R2 are not both H), (ix) water and a water miscible solvent selected from a water miscible organic solvent and a water miscible alkanol, (x) methanol and a second solvent selected from a 5-12C hydrocarbon, a 2-5C alkanol, a 3-12C ketone, a 3-12C carboxylic ester, a 4-10C ether, benzene (optionally substituted by one or more substituents selected from 1-4C alkyl, 1-4C alkoxy, nitro or halo), (xi) a 5-12C hydrocarbon, a 3-12C carboxylic ester, a 4-10C ether of from 4 to 10 carbon atoms, benzene (optionally substituted by one or more substituents selected from 1-4C alkyl, 1-4C alkoxy, nitro or halo), and a polar aprotic solvent; and (c) isolating the 6-O-methylerythromycin A form II crystals.
Patent PT-978743-E (PT)
Inventor: HECHT REINHARD
IPC: G02B6/50
Filed: 1998-08-07
Abstract: The installation of support rings within large diameter pipes or ducts (14) is made using a robotic vehicle (18) that is supported on wheels (20). The vehicle tows a carriage (12) that latches with a coupling (28). The rings are located in sequence on the carriage and are handled automatically and placed into position.