baber/WOPTO huggingface dataset:
Patent CA-2614191-A1 (CA)
Title: Antisense antibacterial method and compound
Inventor: GELLER BRUCE L
IPC: C12Q1/68
Filed: 2006-07-13
Abstract: An antibacterial antisense conjugate and method of using the same for treating a bacterial infection in a mammalian host are disclosed. The conjugate includes an antisense oligonucleotide conjugated to a carrier peptide that significantly enhances the antibacterial activity of the oligonucleotide. The antisense oligonucleotide contains 10-20 nucleotide bases and has a targeting nucleic acid sequence complementary to a target sequence containing or within 10 bases, in a downstream direction, of the translational start codon of a bacterial mRNA that encodes a bacterial protein essential for bacterial replication, where the compound binds to a target mRNA with a Tm of between 50~ to 600C. The carrier peptide is an arginine-rich peptide containing between 6 and 12 amino acids.
Patent CA-2616156-A1 (CA)
Title: Nasel formulations of recombinant human erythropoietin (rhepo) with low content of sialic acid for the treatment of diseases of the central nervous system
Inventor: SUBIROS MARTINEZ NELVYS
IPC: A61P9/10
Filed: 2006-07-27
Abstract: The invention relates to the biopharmaceutical industry and, in particular, to the development of a medicament which is intended for the treatment of cerebrovascular, neurodegenerative and psychiatric diseases and which contains, by way of active principle, recombinant human erythropoietin (rh-Epo) with a low sialic acid concentration. During rh-Epo production, the glycoprotein is obtained with a different sialic acid concentration when less than 40 % of the molecule thereof is protected with (basic) sialic acid, in which case it is not biologically active by systemic route and is inactivated by hepatic enzymes. Surprisingly, it was found that nasally-administered basic rh-Epo has greater therapeutic benefits than the acid. The inventive basic rh-Epo nasal formulations include bioadhesive polymers which increase the residence time in the nasal cavity, thereby enhancing the therapeutic effect thereof. Said formulations also include other auxiliary substances, such as preservative substances, surfactants, pH regulators, isotonising agents and protein stabilisers.
Patent CA-2617449-A1 (CA)
Title: Peptide conjugate for oral delivery of hydrophilic peptide analgesics
Inventor: BELYEA CHRISTOPHER IAN
IPC: A61P25/04
Filed: 2006-08-02
Abstract: The present invention provides a method of improving the oral delivery of a parent peptide, comprising the step of linking the parent peptide to an added peptide to form a conjugate which has greater oral bioavailability than the parent molecule alone, the added peptide comprising a balance of hydrophobic and hydrophilic residues as defined herein. Conjugates for use in the method are also provided, as are pharmaceutical compositions comprising the conjugate and methods of treatment using the conjugate or pharmaceutical composition.
Patent CA-2619413-A1 (CA)
Inventor: ARMSTRONG DAVID N
IPC: A61B17/12
Filed: 2006-03-16
Abstract: An anoscope for ligating internal hemorrhoids has an outer tubular body with lateral hemorrhoid-receiving apertures coinciding with the normal location of internal hemorrhoids in man, and a generally bullet-shaped head to close the distal end of the anoscope and to protect the operator from escaping gas and bowel content. A rotatable inner obturator has lateral apertures that register with the lateral apertures of the outer tubular body when the anoscope is open and intermediate slats that occlude the lateral apertures when the anoscope is closed.
Patent CA-2619766-A1 (CA)
Inventor: SCHOENBACH KARL H
IPC: A61N1/00
Filed: 2006-08-21
Abstract: Method and apparatus for cellular and intracellular manipulation of cell functions with ultrashort electrical pulses and for targeted delivery of the electrical pulses into cell cultures, patients, and tissues.
Patent CA-2620891-A1 (CA)
Inventor: MEIER THOMAS
IPC: A61P21/00
Filed: 2006-08-22
Abstract: The invention relates to the use of a compound of the formula (I), or a pharmaceutically acceptable addition salt thereof for the preparation of a medicament for the prophylaxis and/or treatment of muscular dystrophy.
Patent CA-2621847-A1 (CA)
Inventor: PICCARIELLO THOMAS
IPC: C12P13/04
Filed: 2006-09-08
Abstract: The invention relates to compositions of amino acid and peptide conjugates comprising T3 and/or T4. The T3 or T4 is covalently attached to at least one amino acid via the N-terminus, the C-terminus, a side chain of the peptide carrier, and/or interspersed within the peptide chain. Also discussed are methods for protecting and administering active agents and methods for treating thyroid disorders.
Patent CA-2622376-A1 (CA)
Inventor: CONROY DAVID
IPC: B67D7/84
Filed: 2006-09-14
Abstract: A bracelet to be worn on the wrist which includes a dispenser for dispensing liquid or powdered materials such as sunblocks or germicides. The dispenser on the palm side of the wrist and when the user presses an activator, the dispenser emits a portion of the material onto the user's palm. The dispenser is approximately the size of a wrist watch. A preferred embodiment of the dispenser employs a pump which will work at any orientation. The pump uses air pressure differences produced by the movement of a piston to pull the material into a chamber and expel it from the chamber through a one-way valve. The one-way valve in a preferred embodiment of the pump is made from a silicon diaphragm which opens when it flexes in response to pressure differences and a support for the diaphragm which permits it to flex in only one direction.
Patent CA-2622502-A1 (CA)
Inventor: MORO LUIGI
IPC: A61K31/567
Filed: 2006-06-08
Abstract: The present invention relates to the use of C3-C10 17.alpha.-esters of 9,11-dehydrocortexolone as agents for inhibiting gonadotrophin secretion. The present invention therefore relates to the use of C3-C10 17 .alpha.-esters of 9,11- dehydrocortexolone for the preparation of a medicine for the treatment of disorders associated with the secretion of gonadotrophin and with the corresponding pharmaceutical compounds. The present invention relates specifically to the use of 9,11-dehydrocortexolone 17.alpha.-butyrate.
Patent CA-2625929-A1 (CA)
Title: Swing assembly
Inventor: TSENG CHUEN-JONG
IPC: A63G9/00
Filed: 2008-03-17
Abstract: A swing assembly includes a main support frame and a swing unit. The main support frame includes left and right upright frames, and a top frame connected to top ends of the left and right upright frames. The swing unit includes a swing chair, and left and right hanging assemblies connected to the swing chair and hung on the top frame. The swing chair includes a seat having left and right seat portions connected to each other and extending respectively to the left and right hanging assemblies. One of the left and right seat portions is pivotal relative to the other one of the left and right seat portions to move between a substantially horizontal position and an inclining position.
Patent CA-2628416-A1 (CA)
Inventor: REINAUER ROBERT L
IPC: G06F17/00
Filed: 2006-11-29
Abstract: Le retardement du lancement de certaines applications peut avoir pour résultat d'améliorer l'efficacité globale d'un système. Les applications devant être retardées peuvent être placées dans un objet contenant ou dans une boîte de sorte qu'elles puissent être tracées et que d'autres applications dépendant des applications retardées puissent être traitées de manière appropriée.
Patent CA-2628797-A1 (CA)
Title: Process for making wood laminates using fast setting adhesives at ambient temperature
Inventor: NIECKARZ GREGORY F
IPC: B32B37/00
Filed: 2006-11-06
Abstract: A process to form a multilayer article comprising pressing a stack comprising two or more panels, wherein each panel comprises a surface layer and a substrate layer, wherein a side of the surface layer is contacted to a side of the substrate layer, and wherein the contacting sides of the surface layer and substrate layer have a fast setting adhesive disposed there between; and wherein pressing comprises applying uniform pressure to the stack orthogonal to the plane of the panels, at ambient temperature and for a time of 0.1 to 20 minutes, and with no subsequent hot pressing. Articles prepared using the method are also disclosed.
Patent CA-2630912-A1 (CA)
Inventor: OVSTETUN FRANK
IPC: C25C3/22
Filed: 2006-11-24
Abstract: The present invention concerns a method and device in connection with an electrolytic cell of the Hall-Heroult type for the production of aluminium.  The method relates to the handling of covers in a superstructure in an electrolytic cell, whereby the cell comprises one or more removable covers mounted side by side. Such covers are removed in connection with operations on the cell and are put back into position when the operations have been completed. In connection with the method in accordance with the present invention, the covers are removed by the total sideways extent of the covers being reduced by the covers being moved together sideways before they are lifted off. The device in accordance with the present invention relates to covering the electrolytic cell, whereby at least one cover is designed with at least one side edge that overlaps an adjacent fixed or movable cover and is mounted with a mutual sideways clearance from the fixed or movable cover stated to allow a certain mutual sideways movement between the covers.
Patent CA-2635005-A1 (CA)
Inventor: QUESNELLE RANDAL
IPC: E04D13/04
Filed: 2008-06-13
Abstract: According to the invention there is provided a rain channel for protecting a roof from water flowing out of a downspout. The rain channel comprises a base formed by an elongated sheet of flat, water impervious material, and a pair of upstanding, spaced--apart barrier tabs extending a length of the base.
Patent CA-2637328-A1 (CA)
Title: Identification means
Inventor: ROWE CHRISTOPHER
IPC: A61B19/00
Filed: 2006-11-07
Abstract: A pump supplies pressurized air to inflate compression garments, mattresses, cushions, or similar at the desired times and to desired pressures appropriate to the therapy. The garments are each identified by small steps generated in the pressure waveform during inflation, with the identifying means including a flat sheet valve in the connector chamber having vents to atmosphere and being situated along the flow path from the pump to the garment(s). As the air flows through the connection tubing and through the connector a pressure wave is generated by the valve and fed back upstream to a pressure sensor in the pump. The shape of the pressure waveform identifies a particular compression garment, the pump supplying the appropriate inflation regime upon detection of this pressure waveform.
Patent CA-2637373-A1 (CA)
Inventor: VON BORSTEL REID W
IPC: A61K31/12
Filed: 2007-01-22
Abstract: Agents useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, polycystic ovary syndrome, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis are disclosed, wherein n is 1 or 2; m is 0, 1, 2, 3 or 4; q is 0 or 1; t is 0 or 1; R1 is alkyl having from 1 to3 carbon atoms; R2 is hydrogen, halo, alkyl having from 1 to 3 carbon atoms, or alkoxy having from 1 to 3 carbon atoms; A is phenyl, unsubstituted or substituted by 1 or 2 groups selected from: halo, hydroxy, alkyl having 1 or 2 carbon atoms, perfluoromethyl, alkoxy having 1 or 2 carbon atoms, and perfluoromethoxy; or cycloalkyl having from 3 to 6 ring carbon atoms wherein the cycloalkyl is unsubstituted or one or two ring carbons are independently mono-substituted by methyl or ethyl; or a 5 or 6 membered heteroaromatic ring having 1 or 2 ring heteroatoms selected from N, S and O and the heteroaromatic ring is covalently bound to the remainder of the compound of formula (I) by a ring carbon.  Alternatively, the agent can be a pharmaceutically acceptable salt of the compound of formula (I).
Patent CA-2640088-A1 (CA)
Title: Compositions and methods for inhibition leukocyte function
Inventor: SCHWARTZ MARTIN A
IPC: A61K38/00
Filed: 2007-01-24
Abstract: The present invention provides compositions and methods for regulating leukocyte migration and function. The present invention also provides compositions and methods for preventing and inhibiting lung injury and damage associated with neutrophil infiltration of the lung.
Patent CA-2642216-A1 (CA)
Title: New crystal forms and pharmaceutical compositions of (+)-r-zileuton
Inventor: HANKO JASON A
IPC: C07D333/58
Filed: 2007-02-21
Abstract: Crystalline forms of (+)-R-zileuton, which may be used in pharmaceutical applications, are disclosed. Particular single crystalline forms of (+)-R-zileuton are characterized by a variety of properties and physical measurements. As well, methods of producing crystalline (+)-R-zileuton, and using it to inhibit 5-lipoxygenase activity in subjects to treat a number of diseases, are also discussed.
Patent CA-2642440-A1 (CA)
Title: Packing for injection device
Inventor: GYRN STEFFEN
IPC: A61M5/158
Filed: 2007-02-13
Abstract: This invention relates to a packing for an injector device for the placement of a subcutaneous infusion set on a patient. An insertion needle used in conjunction with an injector device is employed for transcutaneous placement of a soft and relatively flexible tubular cannula, followed by removal of the insertion needle and subsequent infusion of medical fluid to the patient through the cannula. The packing according to the present invention can storage an injector device combined with an infusion set and an insertion needle under sterile conditions. The packing comprises at least - a first storage room storing the injector device combined with an infusion set and an insertion needle, - a first part (1) providing a further storage room (9b) isolated from the insertion needle (312, 26), is constructed with a bottom part (2a, 2b) and walls (2c) standing upright form the bottom part (2a, 2b), - a second part which is attached to the first part (1) before use in such a way that the conditions inside the packing remain sterile, and seen from a sectional view through the walls (2c), the walls (2c) are forming at least two sections each formed as a partial circle with at least two centres C1 and C2 and the centres C1 and C2 are placed with a distance D between them.
Patent CA-2643133-A1 (CA)
Inventor: PRESSMAN NORMAN J
IPC: B01F35/60
Filed: 2002-10-21
Abstract: Apparatus and method for processing specimens, e.g., biological specimens, to extract samples for both liquid (i.e., extracellular) and slide-based (i.e., intracellular) testing. Both types of samples can be obtained from a single fluid specimen. A fluid sampling station removes fluid for a specimen container and places it in a sample receptacle. A specimen acquisition station removes fluid from the container, separates particulate matter (e.g., cells) from the removed fluid, and forms a sample layer of particulate matter, which is transferred to a slide. The two sampling operations can be carried out in any order. The fluid sample receptacle may have a special one-way valve arrangement. The apparatus can be automated so as to process multiple fluid specimens in their respective containers. The machine according to this invention is a "platform instrument" that can produce all required liquid samples and slide-based samples for essentially all cytopathology tests.
Patent CA-2643754-A1 (CA)
Inventor: BALA ARAVIND
IPC: G06F3/048
Filed: 2007-02-23
Abstract: A user can access a searching component that allow the user to enter search terms to search for command associated with a computer program. The most likely command are provided to the user, and a command can be selected fo execution.
Patent CA-2644921-A1 (CA)
Inventor: HALES JOHN
IPC: D05B97/08
Filed: 2008-11-26
Abstract: In the field of garment manufacture there is a need for an improved manner of joining two stretchable fabric portions to one another, in a desired configuration, that produces an unobtrusive join of sufficient strength which is able to accommodate stretching of the fabric portions.   A method of joining first and second stretchable fabric portions (32, 36) to one another in a desired configuration comprises the steps of sewing a first thread (12) through at least one of the first and second fabric portions (32, 36) to define a first stitch formation (14); looping a second thread (16) within the first stitch formation (14) such that the second thread (16) and the first thread (12) overlap one another to create a sewn seam, one of the threads (12, 16) being a fusible thread and the other of the threads (12, 16) being a non-fusible thread; positioning the first and second fabric portions (32, 36) relative to one another in a desired configuration; melting the fusible thread; and forming a plurality of discrete bonding element portions (20) extending along a bonding path (18).  The discrete bonding element portions (20) retain the first and second fabric portions (32, 36) in the desired configuration.   A fabric construction comprises first and second stretchable fabric portions (32, 36) joined to one another in a desired configuration and a plurality of discrete bonding element portions (20) formed from a fusible thread. The discrete bonding element portions (20) extend along a bonding path (18) and retain the first and second fabric portions (32, 36) in the desired configuration.     A garment comprises a fabric construction as described hereinabove.
Patent CA-2645267-A1 (CA)
Inventor: CHAKRABARTY TAPANTOSH
IPC: B08B3/08
Filed: 2008-11-26
Abstract: The use of a solvent for bitumen extraction, either from mined oil sands or in situ.  The solvent includes (a) a polar component, the polar component being a compound comprising a non-terminal carbonyl group; and (b) a non-polar component, the non-polar component being a substantially aliphatic substantially non-halogenated alkane. The solvent has a Hansen hydrogen bonding parameter of 0.3 to 1.7 and/or a volume ratio of (a): (b) in the range of 10:90 to 50:50.
Patent CA-2645514-A1 (CA)
Inventor: BATHON TOBIAS
IPC: F16B12/04
Filed: 2008-12-01
Abstract: Connection device having at least one receiving building component, in particular a wooden body (1), which comprises at least a retention recess (2), in particular a con-tinuous retention recess, and having a composite body (3) which is inserted into the retention recess (2) in the wooden body (1), wherein a composite mass (4) is curably inserted in an interstice (7) in the retention recess (2) between the wooden body (1) and the inserted composite body (3) such that the composite body is substantially frictionally secured in said retention recess (2), wherein an intermediate layer (5), in particular as a formation of the surface of the composite body and/or the composite mass, is at least partially provided between the composite body and the composite mass, providing at least partial decoupling of the composite mass from the composite body.
Patent CA-2648005-A1 (CA)
Inventor: JUNG JIN-HYUK
IPC: H04J11/00
Filed: 2007-04-12
Abstract: L'invention concerne un procédé permettant de placer des signaux de référence dans un système de communication sans fil. Le procédé consiste à préparer plusieurs sous-trames pour plusieurs antennes, à placer un signal de référence pour une sous-trame et à placer un signal de référence pour une autre sous-trame qui ne chevauche pas le signal de référence de l'autre sous-trame; le signal de référence d'une sous-trame et le signal de référence d'une autre sous-trame sont successivement placés sur des symboles MROF contigus ou sur des sous-porteuses contiguës. Ledit procédé permet d'éviter que l'estimation de canal ou la démodulation de données ne subisse une dégradation de performance.
Patent CA-2651036-A1 (CA)
Inventor: SANTIAGO JUAN G
IPC: H01M8/04
Filed: 2007-05-25
Abstract: A polymer electrolyte membrane fuel cell water management device is provided. The device includes a hydrophilic water transport element spanning from inside the fuel cell to outside the fuel cell and disposed between a gas diffusion layer and a current collector layer in the cell. The transport element includes an intermediate wick outside the fuel cell that is hydraulically coupled to the transport element, and has a transport element structure integrated with a flow field structure within the fuel cell. The device further includes an electroosmotic pump, where the pump is located outside the fuel cell and is hydraulically coupled to the intermediate wick. The hydraulically coupled pump actively removes excess water from the flow field structure and the gas diffusion layer through the transport element, where a key aspect of the invention is the decoupling of water removal from oxidant delivery and reduced parasitic loads.
Patent CA-2651214-A1 (CA)
Title: Tension indicator
Inventor: HARRISON IAN
IPC: B60R22/48
Filed: 2007-05-08
Abstract: The present invention concerns a tension indicator for indicating when a strap (2) has reached a predetermined tension level, comprising an audible signal producing member (7) having an abutment surface for engagement with said strap, said audible signal producing member altering its physical configuration in reaction to tension in said strap reaching a predetermined value, wherein the change in physical configuration creates an audible signal.
Patent CA-2653023-A1 (CA)
Inventor: YAHATA TATSUHITO
IPC: A61K47/02
Filed: 2007-05-25
Abstract: An oral composition comprising 3-[5-[4- (cyclopentyloxy)-2-hydroxybenzoyl]-2-[(3-hydroxy-1,2- benzisoxazol-6-yl)methoxy]phenyl]propionic acid or a salt thereof and polyvinylpyrrolidone. The oral composition is useful as a pharmaceutical composition for oral application having the following properties (1) to (3): (1) no new-type facility is required for the production of the composition; (2) the composition can be produced by a simple process; and (3) the composition can be dissolved stably in the gastrointestinal tract even when the pH value in the gastrointestinal tract varies and therefore is improved in gastrointestinal adsorption.
Patent CA-2653199-A1 (CA)
Title: Additives for foaming polymeric materials
Inventor: GRANLUND NEIL
IPC: C08J9/00
Filed: 2007-04-27
Abstract: A foaming additive and a catalyst additive may be used to foam polymeric materials having a low melt flow rate. The foaming additive may include a blowing agent and a hydrophilic component, and the catalyst additive may include a catalyst and a hydrophilic component. Since both the blowing agent and the catalyst are initially combined with a hydrophilic component, the blowing agent and the catalyst are able to find each other easier after being added to the polymeric materials. This makes it simple and economical to make low density foamed materials using polymeric materials having a low melt flow rate.
Patent CA-2656006-A1 (CA)
Inventor: TAMBAKAKIS STEFANOS
IPC: E04B1/98
Filed: 2006-12-12
Abstract: This invention refers to curtain walls capable of resisting the seismic forces of major earthquakes without breakage of their glass panes and without deformation or distortion of their structure. The above can be achieved through the operational separation of the curtain wall of each storey from those of adjacent storeys, by formation of a sliding line on the top of the windows (2.3), through the mutual hooks of suspension of the windows (6.3, 6.10) so that the displacement of the one storey to be independent from the others. The structure of the curtain wall of each storey confined only to the fixed part of the curtain wall of the storey and consists of the uprights (3.1), the sill-beam (3.2), the lintel-beam (3.3) and the attachments (3.4). There are no uprights in the region of windows. The uprights of the structure of curtain wall of each storey at no case are touching the glass panels. The interstorey drifts (.delta.) are in all directions absorbed by the suspension joints of the windows (7.5) and (7.6) and the angle profiles (10).