baber/WOPTO huggingface dataset:
Patent CA-2463685-A1 (CA)
Title: Novel .beta.-phenyl-.alpha.-oxysubstituted propionic derivatives: process for its preparation and their use in the preparation of pharmaceutically important compounds
Inventor: DAS SAIBAL KUMAR
IPC: A61P3/10
Filed: 2002-10-15
Abstract: The present invention relates to novel propionic acid derivatives. More particularly, the present invention relates to beta-phenyl alpha-oxysubstituted propionic acids of the general formula (I). The present invention also relates to processes for the preparation of compounds of the formula (I) and their use in the preparation of compounds of formula (II).
Patent CA-2464269-A1 (CA)
Title: Method and apparatus for scrubbing gases, using mixing vanes
Inventor: TRIVETT ANDREW
IPC: F01N3/04
Filed: 2002-11-28
Abstract: A scrubber for exhaust gases comprises a series of nested counter-flow passages including a hot plenum having a star-shaped section. Exhaust gases from the hot plenum surge through a liquid bath and flow in a reverse direction through an inclined array of flat, overlapping, spaced mixing vane s, causing turbulence in the exhaust gases and the formation of highly disperse d tiny bubbles, which enhance the solution of gaseous pollutants into the scrubbing liquid. Mist eliminator vanes strip entrained liquids from the exhaust gases. The hot plenum, reheats the exhaust gases to an unsaturated level. The scrubber is highly effective in reducing particulate matter, stripping sulphur dioxide and nitrogen dioxide from exhaust gases, and reducing the heat signature and visual evidence thereof.
Patent CA-2464633-A1 (CA)
Title: Protective apparel
Inventor: BEADLE BRIAN ALAN
IPC: A62B18/04
Filed: 2002-09-03
Abstract: Apparel suitable for providing protection against noxious agents, wherein the apparel comprises a laminate material that provides a substantially effective barrier against the noxious agents. It is preferred that the laminate material comprises two or more layers, at least one of which is a barrier layer that is a substantially effective barrier against the noxious agents and at least one of which is a protective layer that protects the at least one barrier layer.
Patent CA-2465127-A1 (CA)
Inventor: MACISAAC GARY
IPC: H04L12/24
Filed: 2001-11-16
Abstract: A system and method of analyzing data traffic associated with messages being sent through a communications network is provided. The method comprises receiving data traffic, obtaining characteristics of data traffic and identifying packet flooding by analyzing the characteristics. The system and method may analyze the data traffic to determine whether the data traffic is not bursty. The system and method may also correlate characteristics of the data traffic to a Hurst parameter. The system and method may respond to packet flooding by terminating a connection associated with data traffic. Denial of service attacks can be prevented by analyzing statistics regarding the network data traffic.
Patent CA-2465980-A1 (CA)
Title: Erosion resistant drilling head assembly
Inventor: LOOPER PATRICK M
IPC: E21B33/08
Filed: 2002-09-27
Abstract: A rotary drilling head assembly for a well bore, including an erosion resistant bowl apparatus. The bowl comprises a bowl member (1), the bowl member (1) having a central receiving cavity (1A) configured to receive a rotary sealed bearing assembly (3), the bowl member (1) having a discharge nozzle extending therefrom, the discharge nozzle (40) fluidly communicating with the receiving cavity (1A), and at least one diverter member (102) extending from an inner surface of the receiving cavity (1A) of the bowl (1), the diverter member formed and configured to disrupt patterns of fluid flow within the bowl (1) during drilling operations. The apparatus preferably includes at least one nozzle diverter member (108) extending from an inner surface of the discharge nozzle (40). A plurality of diverter members (102) preferably extend from an inner surface of the receiving cavity (1A) of the bowl (1) and from the discharge nozzle (40).
Patent CA-2472901-A1 (CA)
Title: Lifesaving floatation and breathing device
Inventor: STEWART ROBERT E
IPC: A62B7/02
Filed: 2004-07-05
Abstract: This lifesaving floatation and breathing device comprises first and second inflatable bags having similar bag volumes, and a mouthpiece communicating with both bags. A pressurized gas cylinder filled with breathable gas is mounted to one of the bags. This pressurized gas cylinder has a gas volume and a gas pressure therein. The device also has an inflator mechanism mounted thereto for transferring the breathable gas from the pressurized gas cylinder into one of the bags. One of the characteristics of the device is that the volume of each bag is a mathematical product of the gas volume inside the cylinder and a ratio of the gas pressure inside the cylinder over atmospheric pressure. Either bags can accept the full content of the cylinder at atmospheric pressure, thereby obviating the need for a pressure regulator or flow control orifice therein.
Patent CA-2481543-A1 (CA)
Inventor: WARREN BRENT
IPC: B03B9/02
Filed: 2004-09-14
Abstract: A drilling fluid for use in high oil viscosity formations containing tar, sand and oil entrained therein. The drilling fluid can be comprised of a polymer in an amount from between .05% and 5% by volume, a solvent in an amount from between 1% and 20% by volume and de-emulsifier in a.n amount from between .05% and 10% by volume.
Patent CA-2484726-A1 (CA)
Inventor: MCKAY DAVID
IPC: A23G9/22
Filed: 2004-10-12
Abstract: The present invention relates to an apparatus and method for grasping, retaining, inverting, coating and transporting a plurality of frangible conical confection shells. The present invention also relates to a modular and reconfigurable manufacturing system for producing frozen cone confections and the like.
Patent CA-2484959-A1 (CA)
Title: Quinoline derivatives as caspase-3 inhibitor, preparation for producing the same and pharmaceutical composition comprising the same
Inventor: KIM SUNG-GYU
IPC: A61P25/16
Filed: 2003-04-30
Abstract: The present invention relates to new quinoline derivatives of formula (1) or their pharmaceutically acceptable salts with caspase-3 inhibitory activity and their preparation methods, wherein R2 is H; halogen; C1-6alkyl; C 1-6 alkoxy;  C1-6 alkoxyalkyl; or C3-6cycloalkyl; R1 is formula (a); -CN; or formula (b); R  is H; C6-14aryl unsubstituted or substituted by halogen, C1-6 alkyl, C1-6 alkoxy or amino; 5 - 15 membered heterocyclic group unsubstituted or substituted by halogen, C1-6 alkyl, C1-6 alkoxy or amino; or -(CH2)n-CHR4R5.  The present invention relates to a pharmaceutical composition for treating caspase-associated diseases by inhibiting the activity of caspase-3 which comprises the compound of formula (1) or its pharmaceutically acceptable salt.
Patent CA-2485496-A1 (CA)
Inventor: HECHT GIL
IPC: B22F3/035
Filed: 2003-05-20
Abstract: The present invention provides a method for producing a powdered metal compact for a cutting head to be used in a metal cutting tool. The powdered metal compact is produced in a punch and die assembly and has apertures communicating between a coolant channel and recesses.
Patent CA-2487433-A1 (CA)
Title: Total spinal support
Inventor: KEILHAUER ED
IPC: A47C7/46
Filed: 2003-05-26
Abstract: The invention provides a support device for use in supporting a user's spine while in a seated position, including lower, top and intermediate sections merged smoothly in a rigid piece. The device extends the entire length of the user's spine from occipital region to coccyx, and includes lateral support for maintaining a centred spinal position. The device preferably sits on the seat of a chair or automobile seat and leans against the back of the seat to support the user's spine. The intermediate section of the device is preferably narrow to sit flush with the user's back between the shoulder blades (scapulae) and allowing the user to rotate to either side in the seat. The support is preferably constructed with a flocked or fabric-covered foam exterior over a rigid plastic armature.
Patent CA-2488435-A1 (CA)
Title: Laparoscopic bipolar electrosurgical instrument
Inventor: SCHMALTZ DALE F
IPC: A61B18/14
Filed: 2003-06-03
Abstract: A laparoscopic bipolar electrosurgical instrument (10) for sealing tissue includes a handle (14) having an elongated tube (13) affixed thereto. The tube includes first (15) and second (16) jaw members having electrically conductive sealing surfaces (39, 40) attached to a distal end (12) thereof which are movable from a first position for approximating tissue to a second position for grasping tissue therebetween. The handle (14) includes a fixed handle (50) and a handle (52) which is movable relative to the fixed handle to effect movement of the jaw members (15, 16) from the first position to the second position for grasping tissue. The jaw members connect to a source of electrosurgical energy such that the opposable sealing surfaces are capable of conducting electrosurgical energy through tissue held therebetween. A stop (33, 90, 95) is included for maintaining a minimum separation distance between opposing sealing surfaces (39, 40). A ratchet (60, 62) is also included to maintain a closure force in the range of about 7 kg/cm2 to about 13 kg/cm2 between opposing sealing surfaces.
Patent CA-2489170-A1 (CA)
Inventor: HIGGINS CHRISTOPHER
IPC: E01D19/12
Filed: 2004-12-01
Abstract: A prestressed or post-tensioned composite structural system for bridge floors, road beds, pedestrian walkways, building floors, building walls, or similar structural elements. The structural system comprises a composite structure comprising an unfilled grating as a base component, and a prestressed, post-tensioned reinforced concrete slab as a top component. The base grating component is preferably a plurality of main bearing bars without any distribution bars or tertiary bars.  The upper portions of the main bearing bars are embedded in the concrete component permitting horizontal shear transfer and creating a composite deck structure which maximizes the use of tensile strength of steel and the compressive strength of concrete.
Patent CA-2492257-A1 (CA)
Title: A damper assembly exploiting a crankshaft
Inventor: JUNEAU NORMAND
IPC: F24F13/14
Filed: 2005-01-11
Abstract: A damper assembly exploiting a crankshaft to induce displacement of a damper means from one position to another.
Patent CA-2494455-A1 (CA)
Title: Electrical fuse relay box and method of manufacture
Inventor: ROOSDORP JOANNES WILLEN MARIA
IPC: B60R16/02
Filed: 2003-07-30
Abstract: A pre-assembled electrical fuse relay box comprising a frame, wherein the frame comprises an upper compartment, a lower compartment, and at least one locking receiver. The fuse box further comprises a plurality of electrical components pre-assembled within the upper compartment, a plurality of connector modules pre-assembled within the lower compartment, an upper cover pivotally mounted on the upper compartment, and a lower cover pivotally mounted on the lower compartment, wherein the connector modules are dimensioned and configured for electrically engaging electrical wires. Each of the upper and lower covers comprises a locking member dimensioned and configured to engage the locking receiver. Moreover, the electrical components comprise relays, circuit breakers, J-case fuses, and blade fuses. The connector modules comprise connection contacts, which extend through the frame and make an electrical connection with the electrical components.
Patent CA-2496790-A1 (CA)
Title: Plant extracts stimulating nitric oxide production and their use in the treatment of inflammation and related diseases
Inventor: MANTIONE KIRK
IPC: A61K31/00
Filed: 2003-08-19
Abstract: The invention relates to nitric oxide (NO) stimulating extracts from various plants. Such extracts contain compounds known as healthin I and healthin II.  Specifically, the invention provides partially purified plant extracts that have NO stimulating activity, methods of isolating and partially purifying such extracts from plant materials. In addition, the invention provides methods and materials for treating diseases and conditions that require modification of cellular levels of NO, for example, diseases and conditions involving inflammation.
Patent CA-2497703-A1 (CA)
Title: Process for the purpose of determining surface evenness errors in band and particularly steel and metal band and further a surface evenness measuring roller
Inventor: NOE ANDREAS
IPC: G01L5/04
Filed: 2005-02-18
Abstract: The invention concerns a process and a surface evenness measuring roller for the purpose of determining surface evenness measurement errors in steel and metal band comprising at least one measuring head having part measuring heads which part measuring heads are integrated respectively offset by 180° into the roller mantel and supported on two force transmitters and are further separated from the roller mantle by means of a circumferential motion gap and are braced with respect to one another by means of at least one tie rod wherein in the course of a measurement of the band tensile stress distribution over the whole band width the band which band is subject to tension over its whole band width wraps around the surface evenness measuring roller with a predetermined arc of contact and thereby exerts pressing forces onto the surface evenness measuring roller from which pressing forces can be determined the band tension distribution.
Patent CA-2500297-A1 (CA)
Title: Digital content delivery and viewing system and method
Inventor: LIM ROBERT C
IPC: H04L29/08
Filed: 2003-09-26
Abstract: A media distribution system (fig. 1) is provided whereby devices (12a-12j) on a network (14) are provided with native-mode, optimized content viewers adapted to receive and present digital content (16a-16d) provided elsewhere on the network. An agent (160) is downloaded to a device, where it gathers information regarding the device environment and uses that information to identify the appropriate application for that device. The appropriate application for a particular device is then downloaded to the device to enable the device to present the content to a user.
Patent CA-2501006-A1 (CA)
Inventor: EDWARDS FLOYD ALLEN
IPC: G06F3/02
Filed: 2005-03-16
Abstract: A keyboard and multi-line display assembly includes a liquid crystal display and a keyboard having a plurality of keys. At least one key of the keyboard is coupled to the display for contrast control, bypassing a processor of the assembly to which the other keys of the keyboard are coupled for data entry. The contrast control key, which is coupled to the display by a digital potentiometer, allows a user to adjust the contrast of the display on the fly without having to exit a data entry mode or to enter a set-up mode.
Patent CA-2501648-A1 (CA)
Title: Assays to detect or quantify bacterial or viral pathogens and contaminants
Inventor: KARL DANIEL W
IPC: C12Q1/70
Filed: 2003-10-15
Abstract: The present invention provides methods for detecting or quantifying bacteria l and viral pathogens or contaminants in a sample.
Patent CA-2502413-A1 (CA)
Title: Quantitative analysis of protein isoforms using matrix-assisted laser desorption/ionization time of flight mass spectrometry
Inventor: HELMKE STEVE M
IPC: H01J49/00
Filed: 2003-10-30
Abstract: The present invention provides for methods of quantitating the amounts of proteins or peptides, including those that are closely related isoforms, using matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS). Measurement of protein concentrations in vivo has been extremely difficult and problematic, and protein concentrations have not been shown to correlate well with mRNA levels, the standard used in the past. The present invention overcomes the deficiencies of prior methodologies by taking advantage of MALDI-TOF-MS technology and applying it to proteins and peptides in a way that allows for accurate, quantitative measurement in vivo of protein or peptide concentrations.
Patent CA-2504770-A1 (CA)
Title: Excavating tooth point/adapter assembly with rotatably lockable connector structure
Inventor: RUVANG JOHN A
IPC: E02F9/28
Filed: 2003-02-10
Abstract: A replaceable excavating tooth point (12) is telescoped onto an adapter nose (24) and releasably retained thereon by an elongated, flat connector member (60) having an untapered side periphery. The connector member longitudinally extends through aligned point and connector openings (56; 44, 46) and blocks forward removal of the point (12) from the adapter nose. A transverse point sidewall abutment surface (50) facing one end (74/66) of the installed connector member prevents it from moving outwardly through one of the point openings, and a rotatable lock member (62) carried by the other end (72/64) of the connector member and engageable with a groove in the other point opening (44) releasably prevents the connector member from moving outwardly through the grooved point opening. A detent structure (90) releasably holds the lock member in locking and unlocking orientations in which the lock member is prevented from moving parallel to the length of the connector member.
Patent CA-2510663-A1 (CA)
Title: A real time translator and method of performing real time translation of a plurality of spoken word languages
Inventor: JAYARATNE NEVILLE
IPC: G10L15/00
Filed: 2002-12-17
Abstract: A real time translator (101) having a voice receiver or microphone (101), a voice to text converter (102), a text-to-text spoken language translator (10 3) for receiving a first language and translating to a second selected language , a text to speech converter (105) for converting the translated second select ed language to a voice output and a voice emitter or speaker (211) for emitting the voice output. A second voice receiver or microphone (201), a voice to te xt converter (202), a text-to-text spoken language translator (203) for receivi ng a second language and translating to the first selected language, a text to speech converter (105) for converting the translated first selected language to a voice output and a voice emitter or speaker (111) for emitting the voic e output. There is parallel processing of the voice to text conversion and/or text translation and/or the text to voice conversion. Two sound cards (151, 152), or two channels (151A, 151B) operating separately on a sound card (151 ), interface with the first and second voice receivers (101, 201) and first and second voice emitters (111,211) The parallel processing can be by central processing unit (cpu) parallel processing techniques or by software controll ed switching techniques.
Patent CA-2510774-A1 (CA)
Title: Amplified cancer target genes useful in diagnosis and therapeutic screening
Inventor: CAIN COLYN
IPC: C12Q1/68
Filed: 2003-12-19
Abstract: A gene useful as a prognostic indicator of survival of patients afflicted with cancers such as breast cancer is described. Also disclosed are methods for screening potential therapeutic agents, such as antitumor agents, based on their modulation of the expression of a TRIP13 gene, or splice variants thereof, along with methods for diagnosing cancerous, or potentially cancerous, conditions as a result of the expression, or patterns of expression, of such genes, including changes in copy number. Also disclosed are methods for detecting or determining functionally related genes, where disruption of TRIP13 may affect such related-gene expression, as well as methods for treating cancer based on targeting expression products of such genes and determining genes involved in the cancerous process. Methods for identifying, detecting and following patients and others having high levels of amplification/expression of the gene before treatment where differences after treatment serve as markers for indication of success of treatment or for identifying individuals who would benefit from such treatment using this gene marker as a diagnostic and/or prognostic and/or pharmacodynamic or surrogate marker are described.
Patent CA-2517828-A1 (CA)
Inventor: YEAGER JAMES L
IPC: A61K31/00
Filed: 2004-03-22
Abstract: Compositions and methods for the treatment of premature ejaculation are provided wherein a composition comprising a topical anesthetic, a shear-thinning polymeric thickener, a lipophilic component that is selected from the group consisting of an aliphatic C1 to C8 alcohol, an aliphatic C8 to C30 ester, a liquid polyol and mixture thereof, water and a buffer system that provides a buffer system that provides a buffered pH value for the composition in the range of about 3 to about 7.4 is administered to the penile meatus.
Patent CA-2518997-A1 (CA)
Title: Cochlear implant system with map optimization using a genetic algorithm
Inventor: VAN DEN HONERT CHRISTOPHER
IPC: A61N1/05
Filed: 2004-03-11
Abstract: A method for fitting a cochlear implant to a patient uses a genetic algorithm that operates to generate successive generations of multiple groups of values for a parameter subset, after the selection of an initial generation (300), and patient feedback (302) during execution of the genetic algorithm determines the multiple groups of subset values in successive generations. In each generation, half of the groups of values for the parameter subset are selected and used to determine the groups of values for the next generation.  Values for the parameters not included in the subset are selected by any traditional method that does not use a genetic algorithm.
Patent CA-2519511-A1 (CA)
Title: Mutant cholera holotoxin as an adjuvant and an antigen carrier protein
Inventor: HAGEN MICHAEL
IPC: A61P31/00
Filed: 2004-03-11
Abstract: The invention relates to a mutant cholera holotoxin having reduced toxicity, which functions both as an adjuvant and an antigen carrier. In a particular embodiment, the cholera holotoxin is genetically modified at least at amino acid residue 29 of the A subunit, wherein the genetic modification comprises an amino acid substitution of the wild-type glutamic acid at position 29, wherein the substitution is not an aspartic acid.
Patent CA-2521423-A1 (CA)
Inventor: GRUENBACHER DANA PAUL
IPC: A61K9/70
Filed: 2004-03-31
Abstract: The present invention is directed to drug delivery systems which comprise an active ingredient encapsulated within an edible film, wherein the edible film preferably provides for the buccal administration of the active into the bloodstream. The drug delivery systems of the present invention are especially effective in providing for the buccal administration of an encapsulated pharmaceutical active that is highly efficacious in providing sedation and/or sleep benefits.
Patent CA-2523176-A1 (CA)
Inventor: MCKEE TIMOTHY P
IPC: G06F17/30
Filed: 2005-10-11
Abstract: A file system that does not conflate item lifetime with the item's inclusion in an organizational structure of the file system is described herein. In addition, the file system's organizational structure is not limited to directory trees, but instead may use any directed acyclic graph (DAG). Items, once stored into the file system, may be maintained until affirmatively deleted by a client of the file system, regardless of whether the item is part of a DAG or not. Items may be placed in file regions, which are conceptual workspaces for a client to control item lifetime and to organize items into any DAG structure of the user's choosing. Items may be concurrently stored in multiple DAGs, and each file region may have one or more independent DAGs. An item's placement in a DAG may also be used to govern file properties such as namespace, security, privacy, and read/write attributes.
Patent CA-2527369-A1 (CA)
Title: Subgroup b adenoviral vectors for treating disease
Inventor: ASPELUND AMY
IPC: A61K35/761
Filed: 2004-06-22
Abstract: Methods and compositions for treating disease using human subgroup B  adenovirus, vectors derived from such viruses, including expression vector systems in which one or more subgroup B adenoviral genes are replaced by a foreign gene.