baber/WOPTO huggingface dataset:
Patent IL-100054-A0 (IL)
Title: 1,3-bis-(3-(mono-or poly-hydroxy)acylamino-5-(mono-or poly-hydroxy-alkyl)aminocarbonyl-2,4,6-triodo-benzoyl-amino)-hydroxy-or hydroxyalkyl-propanes,their methods of preparation and x-ray contrast media containing them
IPC: C07C237/04
Filed: 1991-11-14
Abstract: Symmetrical or asymmetrical 1,3-bis-[3-(mono- or poly-hydroxy)acylamino-5-(mono- or polyhydroxyalkyl)-aminocarbonyl-2,4,6-triiodo-benzoyl-amino]-hydroxy- or hydroxyalkyl-propanes, useful to constitute the opacifying component of X-ray contrast media, are described.
Patent IL-107708-A0 (IL)
Title: Proteins
IPC: A61K38/00
Filed: 1993-11-22
Abstract: The invention relates to ligand binding variable domains (V-mins) having structural rearrangement of the binding domain of immunoglobulins and other Ligand binding members of the immunoglobulin superfamily. The minimal elements necessary to retain good antigen binding affinity, the complementarity determining region (CDRs) and the central beta barrel structure for the Fv fragment, may be retained positioned appropriately in space by cyclic permutation of the central beta barrel structure and leaving the strands of the beta -barrel intact. The invention is also independently based on recognising that after cyclic permutation of the central beta barrel the framework region which supports the CDRs can be pared down through creation of novel linkages in the structure.
Patent IL-113109-A0 (IL)
Title: Recombinant viruses, their preparation and their use in gene therapy
IPC: C12N15/09
Filed: 1995-03-23
Abstract: Recombinant adenoviruses comprising a heterologous DNA sequence coding for glial-derived neurotrophic growth factor (GDNF) are provided. The recombinant adenoviruses are useful in a method of expressing GDNF in a cell, wherein the cell is present in a mammal suffering from Parkinson's disease, comprising infecting said cell with a replication-defective recombinant adenovirus comprising a DNA sequence encoding GDNF operably linked to a promoter by administering the adenovirus into cells of the central nervous system. The recombinant adenoviruses of the invention are also useful in a method of treating Parkinson's disease comprising administering into cells of the central nervous system of a mammal suffering therefrom a replication defective recombinant adenovirus comprising ITRs, an encapsidation sequence and a DNA sequence encoding GDNF operably linked to a promoter, wherein the adenovirus E1 gene is non-functional and GDNF is expressed at a level that provides a therapeutic effect.
Patent IL-117742-A0 (IL)
Title: Seek actuator for optical recording
IPC: G11B7/085
Filed: 1996-03-31
Abstract: An assembly for controlling the position of a lens (122) in an optical data storage and retrieval drive includes a carriage that suspends a lens holder using a plurality of flexures (260,262). A lens is mounted in the lens holder such that the center of mass of the suspended lens holder lies on the optical axis of the lens, and also coincides with the center of mass of the lens. The lens holder is capable of relative motion with respect to the carriage (106) with at least one degree of freedom. The center of mass of the carriage lies within 0.1mm of the optical axis, proximate the center of mass of the lens holder. Suspensory forces acting on the lens holder are symmetric about the optical axis. A coarse magnetic drive moves the carriage in a tracking direction, and exerts forces on the carriage that are balanced and symmetric about the optical axis, so that moments about the center of mass of the carriage are effectively absent. Inertial forces acting on the carriage, and forces reactive to the magnetic drive forces are also balanced and symmetric with respect to the optical axis, and produce insubstantial moments about the center of mass of the carriage. There is a fine tracking and a focusing drive for the lens holder. Both of these drives produce balanced and symmetric forces about the optical axis, such that moments about the optical axis are absent. Inertial forces and reactive forces acting on the suspended lens holder are also symmetric about the optical axis. As a result the objective lens moves along its optical axis, and in its tracking direction without change in attitude, and its focal point can be precisely controlled with respect to the surface of a storage medium being read or written. <IMAGE>
Patent IL-146921-A0 (IL)
Title: Translation and locking mechanism in missile
IPC: F42B15/36
Filed: 2000-06-02
Abstract: A translation and locking mechanism for a projectile that is lying in a standby position within a rocket motor in a missile, wherein the projectile is translated with respect to the rocket motor by means of a pyrotechnic charge before the rocket motor is ignited. The rear end of the projectile includes at least one radially spring biased lock and the front part of the rocket motor includes an internal circumferential groove that the at least one lock snaps into when the at least one lock is translated to the groove.
Patent IL-148731-A0 (IL)
Title: Seal assembly
IPC: F16J15/00
Filed: 2000-09-15
Abstract: There is described a seal assembly and a method of sealing parallel, planar, arcuate or convex surfaces. The seal assembly comprises a ring seal provided with a pair of primary sealing lips (9, 10), radially disposed on a first, circumferential face of the ring (8); a second, radial face (13, 14) being provided with means (15, 16) for dispersing pressurised fluid. There is also provided a method of introducing a three way joint into a pipeline.
Patent IL-151327-A0 (IL)
Title: 8,8a-dihydro-indeno [1,2-d] thiazole derivatives, substituted in position 8a, a method for their production and their use as medicaments, e.g. anorectic agents
IPC: A61P3/10
Filed: 2001-02-12
Abstract: The invention relates to polycyclic dihydrothiazoles and to their physiologically acceptable salts and physiologically functional derivatives.Compounds of formula I,in which the radicals are as defined above, and their physiologically acceptable salts and processes for their preparation are described. The compounds are suitable, for example, as anorectics.
Patent IL-152307-A0 (IL)
Title: Oxidising electrolytic method for obtaining a ceramic coating at the surface of a metal
IPC: C25D11/30
Filed: 2001-04-25
Abstract: Process for obtaining a ceramic coating on the surface of a metal having semiconducting properties, such as aluminium, titanium, magnesium, hafnium, zirconium and their alloys, by a physico-chemical transformation reaction of the treated metal. This process consists in immersing the metal workpiece (5) to be coated in an electrolytic bath (3) composed of an aqueous solution of an alkali metal hydroxide, such as potassium hydroxide or sodium hydroxide, and of an oxyacid salt of an alkali metal, the metal workpiece forming one of the electrodes, and in applying a signal voltage of overall triangular waveform to the electrodes, that is to say a signal having at least a rising slope and a falling slope, with a form factor that can vary during the process, generating a current which is controlled in its intensity, its waveform and its ratio of positive current to negative current.
Patent IL-156118-A0 (IL)
Title: Coated cutting tool insert with iron-nickel based binder phase
IPC: B23B27/14
Filed: 2001-12-06
Abstract: The present invention relates to cutting tool insert consisting of a tungsten carbide based hard metal substrate and a coating. The hard metal consists of about 4-15 wt-% binder phase with face centered cubic structure and a composition of 35-65 wt-% Fe and 35-65 wt-% Ni in addition to dissolved elements. As a result, inserts have been produced with at least as good performance in machining as conventional state-of-the-art inserts with Co-based binder phase. The insert can be applied in milling and turning of low and medium alloyed steels as well as stainless steels.
Patent IL-173895-A0 (IL)
Title: Imidazopyridine derivatives and pharmaceutical compositions containing the same
IPC: A61P31/00
Filed: 2006-02-23
Abstract: The compounds of Formula (I) in which R1, R2, R3, R4, R5 and A have the meanings as given in the description are novel effective iNOS inhibitors.
Patent IL-177698-A0 (IL)
Title: Fusion proeins comprising modified allergens of the ns-ltps family, use thereof and pharmaceutical compositions comprising the same
IPC: A61K38/00
Filed: 2006-08-24
Abstract: The present invention relates to fusion proteins comprising different allergens of the ns-LTPs family, and their use in the prevention and the treatment of allergic symptoms associated to said allergens. In particular, fusion proteins in the form of heterodimers comprising the major allergens of Parietaria judaica, Parj 1 and Parj 2, are described. Methods of preparation of the fusion proteins by expression in genetically modified host cells and pharmaceutical compositions comprising said fusion proteins are described as well.
Patent IL-186593-A0 (IL)
Title: A process for the purification of 10-deacetylbaccatine iii from 10-deacetyl-2-debenzoyl-2-pentenoylbaccatine iii
Filed: 2007-10-11
Abstract: A process for the preparation of 10-deacetyl-7,10-bis-trichloroacetylbaccatine III with HPLC purity higher than 99% and free from 2-debenzoyl-2-pentenoylbaccatine III by purification of 10-deacetyl-7,10-bis-trichloroacetylbaccatineIII followed by alkaline hydrolysis of the protecting groups in position 7 and 10.
Patent RO-125504-A0 (RO)
Title: Pharmaceutical composition based on plants for treating anorectal affections and process for preparing the same
Inventor: MIRON GHIORGHI
IPC: A61K36/15
Filed: 2009-11-12
Abstract: The invention relates to a pharmaceutical composition used for treating anorectal affections and to a process for obtaining the same. According to the invention, the composition consists, in mass percentage, of 22...25% mixture of oily extract of coniferous resin, oak bark, horsetail (Equisetum arvense L.), yarrow (Achillea millefolium), walnut leaves, celandine, marigold and 75...78% a base for suppositories consisting of a mixture of solid palm-tree oil, bee wax, wool fat, emulsifier of the stearylic cetyl/cetyl stearyl alcohol sodium sulphate type, oily vitamin A, propylene glycol, propolis tincture, propolis oil and distilled water. According to the invention, the process consists in mixing, at a temperature of 50°C, the solid palm-tree oil with the emulsifier, wool fat, vitamin A, propylene glycol, oily propolis extract, afterwards there is added the heated bee wax and a mixture consisting of the oily extracts of coniferous resin, oak bark, horsetail (Equisetum arvense L.), yarrow (Achillea millefolium), walnut leaves, celandine, there is maintained the reaction mass under stirring for 50...70 min and there are added propolis tincture and distilled water, then the mixture is cooled down to the temperature of 45...48°C and it is conditioned as suppository, wherefrom there results a homogenous product with a pH value of 5...5.5 and a peroxide index of maximum 5.
Patent RO-131526-A0 (RO)
Title: Erogonomic seal with intuitive visual- and tactile-marking of unsealing
Inventor: CUC CEZAR
IPC: G09F3/10
Filed: 2016-06-28
Abstract: The invention relates to a seal with intuitive unsealing provided with visual and tactile marks for pointing out a package opening means. According to the invention, the seal has a sandwich-type structure and comprises at least one base material (1) consisting of one or several layers and at least one adhesive (2) to adhere to a substrate (3) represented by a product package, where at least one side has a non-adhesive grasping zone (4) having at least one visual mark (5) and one tactile mark (6) comprising unsealing indications, its constructive shape allowing customization by printing information elements (7) or/and indications (8), while, diametrically opposite to the grasping zone (4), there is an end (9) delimited by some perforations (11) for visual and tactile pointing out of unsealing, when the separated part is detached from the substrate (3) at the limit of the perforations (11).
Patent AP-2003002896-A0 (AP)
Title: Measuring and locating sysytem using bases three and nine and corresponding uses.
Inventor: SEGUR PATRICK
IPC: G01C21/20
Filed: 2002-04-05
Abstract: A device to place an incision into matter with a harmonious plasma cloud. A radiofrequency generator system produces pulsed or continuous electromagnetic waveform which is transmitted by an active transmitter incising electrode tip. This generated electromagnetic wave is utilized to initiate a plasma cloud with processes such as thermal ionization and a photoelectric effect which then trigger an Avalanche Effect for charged atomic particles at the surface of the active transmitter incising electrode tip. This electromagnetic wave is impedance matched, frequency matched, power matched and tuned to the plasma cloud in order to sustain and control a harmonious plasma cloud with reduced atomic particle turbulence and chaos. This harmonious plasma cloud forms a coating over the surface of the active transmitter electrode tip as well as acts to reduce the energy needed from the power amplifier of our plasma cutting device. The electromagnetic wave is also used to produce a Pinch Effect to compress, contour, shape and control the harmonious plasma cloud. The electromagnetic wave is furthermore used to trap and contain the plasma cloud without the need of a solid matter containment vessel according to the Magnetic Bottle Effect of physics and a generated centripetal electric field force that acts to pull plasma particles inward toward the activated incising electrode tip. The Tunnelling Effect of physical chemistry is utilized to focus and amplify the energy delivered to the harmonious plasma cloud while shielding matter surrounding the intended path of incision from potential electromagnetic radiation exposure. The invention is an efficient, effective, safe, clean and inexpensive device which can be used to place an incision in matter.
Patent IE-910769-A1 (IE)
Title: NOVEL DERIVATIVES OF 4H-PYRROLO[1,2-a]¹THIENO[3,2-f][1,4]-DIAZEPINE THEIR PROCESS OF PREPARATION¹AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
IPC: A61P3/06
Filed: 1991-03-08
Abstract: Compounds of general formula I: 
<IMAGE>
 in which: 
 
  - R1 denotes a radical of general formula (Z0), (Z1), (Z2), (Z3) or (Z4) 
<IMAGE>
 
  - R2 denotes a methylene radical, a hydroxymethylene radical, a carbonyl radical or a radical of general formula (Y1), (Y2), (Y3) or (Y4): 
<IMAGE>
 
 or forms with R12 and the nitrogen atom to which they are attached a radical of general formula (W): 
<IMAGE>
 R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 and n being as defined in the description. 
<??>Medications.
Patent LU-84224-A1 (LU)
Inventor: EDOUARD LEGILLE
IPC: C21B7/20
Filed: 1982-06-24
Abstract: A drive means for an oscillating spout is presented which includes a control mechanism which directs a control arm to perform the movement required by the spout and a transmission device which acts to transmit the control arm movement and reproduce it as spout movement. The control mechanism consists of a driving rod pivotally connected to an intermediate lever arm and a universal joint connecting the lever arm to the control arm. A novel movable torque means is associated with the universal joint and enables the spout to be moved in and out of a vertical orientation by overcoming the tendency of the components of the control mechanism to become axially locked in a 180 DEG  angle. The movable torque means accomplishes this result by reducing the angle between the intermediate lever and control arm when that angle reaches 180 DEG .
Patent MA-20856-A1 (MA)
Inventor: PAUL JEROME CRABTREE
IPC: C11D3/00
Filed: 1987-01-19
Abstract: Detergent compositions comprising surfactant, at least one detergency builder, and a plurality of rinse cycle suds control prills comprising fatty acid soap, quaternary ammonium salt, and silicone fluid suds suppressor. The granular detergent compositions of this invention provide control of the level of suds on the surface of the water during the rinse cycle without interfering with the level of suds on the surface of the water during the wash cycle of laundering operations.
Patent MA-25767-A1 (MA)
Inventor: MANGEARD PHILIPPE
IPC: E04D13/03
Filed: 2003-01-23
Abstract: A slatted roofing device, includes a frame (1) receiving a lower series (2) of grid-type mounted slats and at least a support (3) superimposed on the frame (1) receiving an upper series (4) of grid-type mounted slats, the support (3) being transversely mobile with respect to the longitudinal direction of the slats on the frame (1) to modify the lateral position of the slats of the upper series (4) relative to those of the lower series (2), the slats shifting from a completely overlapping position when the roof is open to a partial overlapping position when the roof is closed. The device includes an apparatus for lifting the support (3) relative to the frame (1) to allow air to pass through the roof even when the series of upper (4) and lower slats cover the whole roof surface.
Patent MA-28094-A1 (MA)
Title: Dérivés [3.1.0] bicycliques servant d'inhibiteurs du transporteur de glycine
Inventor: LOWE JOHN A
IPC: A61K/
Filed: 2006-04-14
Abstract: Dérivés [3.1.0] bicycliques servant d'inhibiteurs du transporteur de glycine La présente invention concerne une série d'amines [3.1.0] bicycliques substituées de formule I: dans laquelle A, B, D, Q, V, W, X, Y, Z, R2, R3, R4, R5, R14, R15, R30, o, p, s, t et q sont tels que définis dans le présent mémoire, leurs sels pharmaceutiquement acceptables, des compositions pharmaceutiques les contenant, et leur utilisation pour améliorer la cognition et pour le traitement des symptômes positifs et négatifs de la schizophrénie et d'autres psychoses chez des mammifères, y compris des êtres humains.
Patent MA-20150087-A1 (MA)
Title: Adresse postale electronique
Inventor: KADA AHMED
IPC: G06Q10/00
Filed: 2013-07-18
Abstract: L’adresse postale électronique est une infrastructure et plateforme technique, fonctionnelle et opérationnelle permettant de connecter, dans l’espace numérique marocain, les personnes physiques ou morales de façon sécurisée et confidentielle via l’écosystème de tiers confiance d’un opérateur postal à l’instar des adresses postales électroniques. Cette adresse électronique sécurisée et authentique est orientée pour l’espace numérique marocain. Elle repose sur le nom de domaine « .Post » de l’upu ( union postale universelle). « .Post » est un nom de domaine de premier niveau générique ( generic top-level domain, gtld) sécurisé par les extensions de sécurité dns ( domain name system security extensions- dnssec). Ceci permet de renforcer la sécurité du point le plus haut au point le plus bas du système afin de protéger les usagers de la fraude en ligne. L’adresse postale électronique est unique pour chaque usager, personne morale ou physique. En effet, elle est fonction d’une part de l’identité nationale et en option du certificat électronique de la personne physique, et d’autre part, de l’identité fiscale ou autre identité unique de la personne morale et en option via un certificat électronique qualifié. La plateforme de ladite adresse est basée sur les noms de sous-domaines sous « .Post » de barid al- maghrib et sur l’adresse postale via sa position gps en option. Cette adresse électronique postale est destinée aux applications et systèmes d’échanges de courrier électronique sécurisé et/ou à valeur probante tels que le courrier recommandé électronique et l’email sécurisé. Pour une personne physique l’adresse postale électronique se présente comme suit nom.Prénom.Xxx@postmaroc.Post , xxxx est une fonction de son nom&prénom, son identité biométrique et/ou la position gps de son adresse postale et l’index de son identité numérique. Une adresse électronique postale est liée automatiquement à une ou plusieurs adresses postales.
Patent MA-20150418-A1 (MA)
Title: Sucres alimentaires enrichis de graines de nigelle (nigella sativa )
Inventor: ALAMI OUAHABI FOUZIA
IPC: C12P19/00
Filed: 2014-04-16
Abstract: A l'instar des sucres qui se trouvent sur le marché, sucre d'or, sucre stévia, sucre roux, sucre noir, sucre candi, le sucre à la graine de nigelle (nigella sativa) à très faibles doses viendra enrichir la gamme déjà existante et faire profiter le consommateur des bienfaits ce cette plante médicinale et aromatisante chaque fois que le besoin le dicte. Vu sa richesse en calcium, en zinc, en fer, en potassium, en magnésium, en phosphore, en sodium, en sélénium ; en acides aminés, en vitamines a, 81, 82, 86, pp ; en acide folique ; en lipides, protéines, glucides ... , pour ne citer que certains ; une seule graine de nigelle contient près de 100 produits; elle contribuera à la bonne santé du consommateur si toutefois les dosages sont bien respectés. Pour profiter pleinement du sucre à la graine de nigelle, espacer son utilisation quelques jours puis reprendre à nouveau. Elle reste déconseillée, même à très faibles doses, aux femmes enceintes pendant les 10 premiers jours de la grossesse, aux nourrissons et aux enfants de moins de deux ans. A mentionner sur l'emballage du produit fini.
Patent MA-37500-A1 (MA)
Title: Formulation parentérale d'esmolol
Inventor: WIDMANN RUDOLF
IPC: A61P9/06
Filed: 2013-05-08
Abstract: La présente invention concerne une formulation parentérale de chlorhydrate d'esmolol pour son utilisation dans le traitement d'un patient souffrant de tachycardie qui comprend une poudre lyophilisée constituée de chlorhydrate d'esmolol pur, ladite poudre étant reconstituée pour obtenir une solution i.V. Prête à l'emploi de chlorhydrate d'esmolol à une concentration de 20 à 100 mg/ml, et ladite solution i.V. Est directement administrée au patient. La présente invention concerne également un procédé de production d'une solution i.V. Prête à l'emploi de chlorhydrate d'esmolol par reconstitution d'une poudre constituée de chlorhydrate d'esmolol pur avec un solvant, caractérisé en ce que ledit solvant est un solvant i.V. Dépourvu d'alcool ou d'excipient tampon, en une quantité nécessaire pour obtenir une solution i.V. Prête à l'emploi à une concentration de 20 à 100 mg/ml. La présente invention concerne en outre la solution i.V. Prête à l'emploi contenant une formulation parentérale de 20 à 100 mg/ml de chlorhydrate d'esmolol pur dans un dispositif de perfusion ou consistant en une formulation parentérale de 20 à 100 mg/ml de chlorhydrate d'esmolol pur, d'eau pour injection et/ou de solution saline, et dépourvue de tout alcool ou excipient tampon.
Patent MA-37931-A1 (MA)
Title: Procédés améliorés permettant de traiter un cancer avec une toxicité rénale réduite
Inventor: BOULIKAS TENI
IPC: A61P35/00
Filed: 2012-08-12
Abstract: La présente invention concerne un procédé permettant d'empêcher la croissance d'une tumeur chez un patient atteint d'un cancer ou de traiter un patient atteint d'un cancer, le patient atteint d'un cancer présentant une insuffisance rénale. Le procédé nécessite l'administration d'une quantité efficace de lipoplatine. Un second médicament chimiothérapique peut également être administré au patient. La seconde chimiothérapie peut être administrée avant ou après la thérapie par lipoplatine ou simultanément.
Patent UY-23368-A1 (UY)
Title: Procedimiento para la preparacion de derivados de aminoacido
Inventor: BROADHURST MICHAEL JOHN
IPC: C07C/
Filed: 1992-01-31
Abstract: Un procedimiento para la preparación de compuesos de la fórmula general (I) (figura 1) en donde a representa el grupo (a) o (b) de la figura 2; R1 representa carbamoilo, entre otras posibilidades; R2 representa pirrolidino, entre otras posibilidades; R4 representa benciloxilo, entre otras posibilidades; y sus sales farmaceuticamente aceptables. Como ejemplo no limitante del compuesto preparado por el procedimiento de la invención: N2-[(R)-[hidroxicarbamoilmetil]-4-metilvaleril]-N1, 3-dimetil-L-valinamida. El compuesto se emplea en el control o prevención de enfermedades de la articulaciones degenerativas o para el tratamiento de tumores invasivos, aterosclerosis o esclerosis múltiple.