Patent SG-11201808959Q-A (SG)
Title: Analyte detection methods and apparatus using dielectrophoresis and electroosmosis
Inventor: WEBER MONIKA
IPC: H01J49/00
Filed: 2017-04-14
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 111111111111111111 010111010 11111 0111011111111 010 11111 010 110 111110 111 0111111 Organization 0 International Bureau (10) International Publication Number (43) International Publication Date .....0\"\" WO 2017/181030 A3 19 October 2017 (19.10.2017) WIPO I PCT (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every B03C 5/02 (2006.01) G01N 27/00 (2006.01) kind of national protection available): AE, AG, AL, AM, CO7K 1/28 (2006.01) H01.1 49/00 (2006.01) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, (21) International Application Number: CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, PCT/US2017/027659 DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, (22) International Filing Date: KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, 14 April 2017 (14.04.2017) MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, (25) Filing Language: English SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, (26) Publication Language: English TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (30) Priority Data: (84) Designated States (unless otherwise indicated, for every 62/323,549 15 April 2016 (15.04.2016) US kind of regional protection available): ARIPO (BW, GH, 62/326,665 22 April 2016 (22.04.2016) US GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, (71) Applicant: FLUID-SCREEN, INC. [US/US]; 700 Main TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, Street at LabCentral, Cambridge, MA 02139 (US). EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, (72) Inventor: WEBER, Monika; 350 Third Street, Apt. 1217, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, Cambridge, MA 02142 (US). TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Agent: WEHNER, Daniel, T.; Wolf, Greenfield & Sacks, P.C., 600 Atlantic Avenue, Boston, MA 02210-2206 (US). (74) = = = Title: ANALYTE DETECTION METHODS AND APPARATUS USING DIELECTROPHORESIS AND ELECTROOSMOSIS (54) — = = 4 = = = = = = = FIG. 13 : Methods and apparatus for detection and/or identification of analytes including bacteria using dielectrophoresis and = en en © ,—, cc ,_ 1 (57) \"I r z electroosmotic traps. Switching between different frequencies of an applied electric field results in movement of the analyte between ,-1 dielectrophoresis and electroosmotic trapping states. The use of edge-based sensing techniques enables the use of electrodes with a 0 larger form factor than nanowire sensors. Signal modulation based on analyte contact with the electrode edge is also described. ei C [Continued on next page] WO 2017/181030 A311IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIDEMOMOEIMMIMI100 110 lii0E00# Published: — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) (88) Date of publication of the international search report: 29 March 2018 (29.03.2018)