Patent SG-11201811252P-A (SG)
Title: Optical cylinder and method of surface treatment of the same
Inventor: MEHTA JODHBIR
IPC: A61F2/14
Filed: 2017-07-26
Abstract: ight penetrates through Optical Cylinder Surface coating W O 18/0 2197 1 Al (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 01 February 2018 (01.02.2018) WIP0 I PCT IiiimmoinionotioloomoiolommomoinvuoimIE (10) International Publication Number WO 2018/021971 Al (51) International Patent Classification: A61F 2/14 (2006.01) (21) International Application Number: PCT/SG2017/050381 (22) International Filing Date: 26 July 2017 (26.07.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 10201606175P 26 July 2016 (26.07.2016) SG (71) Applicants: SINGAPORE HEALTH SERVICES PTE LTD [SG/SG]; 31 Third Hospital Avenue, #03-03 Bowyer Block C, Singapore 168753 (SG). NANYANG TECH- NOLOGICAL UNIVERSITY [SG/SG]; 50 Nanyang Av- enue, Singapore 639798 (SG). (72) Inventors: MEHTA, Jodhbir; 8, Gallery 8, Pulasan Road, #05-01, Singapore 424376 (SG). RIAU, Andri; 35, Ever- green Park, Hougang Avenue 7, #02-06, Singapore 538802 (SG). VENKATRAMAN, Subramanian; c/o Nanyang Technological University, 50, Nanyang Avenue, Singapore 639798 (SG). LIEDBERG, Bo; c/o Nanyang Technolog- ical University, 50, Nanyang Avenue, Singapore 639798 (SG). MONDAL, Debasish; c/o Nanyang Technological University, 50, Nanyang Avenue, Singapore 639798 (SG). (74) Agent: SPRUSON & FERGUSON (ASIA) PTE LTD; P.O. Box 1531, Robinson Road Post Office, Singapore 903031 (SG). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (54) Title: OPTICAL CYLINDER AND METHOD OF SURFACE TREATMENT OF THE SAME Figure 9 (57) : Disclosed is an optical cylinder of a corneal prosthesis comprising: a) an optical cylinder comprising a solid polymer (preferably, PMMA), and b) a plurality of nanoparticles (preferably, hydroxyapatite, HAp) forming a substantially uniform layer on a circumference of the solid polymer surface of the optical cylinder. Also disclosed are methods of surface treatment of optical cylinders of corneal prostheses, and corneal prostheses thereof, comprising contacting an optical cylinder with a mixture comprising an organic solvent, a dispersant (i.e. PMMA), and a plurality of nanoparticles via dip- coating. [Continued on next page] WO 2018/021971 Al MIDEDIMODOMMOHIONMEMIMOMHIEMOVOIMIE (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: — of inventorship (Rule 4.17(iv)) Published: — with international search report (Art. 21(3))