Patent SG-11201801384Y-A (SG)
Title: Peptides and combination of peptides for use in immunotherapy against breast cancer and other cancers
Inventor: MAHR ANDREA
IPC: A61K38/17
Filed: 2016-11-29
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -' Organization International Bureau res., 00) (43) International Publication Date ..... ..sr ,„,„.1 29 June 2017(29.06.2017) WIPO I PCT ID Hit (10) WO International 2017/108345 111111111111111111IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIMIIIIIIIIIIIIIII Publication Number Al (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every CO7K 7/06 (2006.01) C07K 16/28 (2006.01) kind of national protection available): AE, AG, AL, AM, A61K 38/17 (2006.01) CO7K 7/08 (2006.01) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, A61K 39/00 (2006.01) CO7K 14/47 (2006.01) BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (21) International Application Number: HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, PCT/EP2016/079059 KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, (22) International Filing Date: MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, 29 November 2016 (29.11.2016) OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, (25) Filing Language: English TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, (26) Publication Language: English ZW. (30) Priority Data: (84) Designated States (unless otherwise indicated, for every 1522667.3 22 December 2015 (22.12.2015) GB kind of regional protection available): ARIPO (BW, GH, 62/270,968 22 December 2015 (22.12.2015) US GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, (71) Applicant: IMMATICS BIOTECHNOLOGIES GMBH TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, [DE/DE]; Paul-Ehrlich-StraBe 15, 72076 Tibingen (DE). DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, L (72) Inventors: MAHR, Andrea; Kirschenweg 22, 72076 V, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, Tubingen (DE). WEINSCHENK, Toni; Im Morgenrain SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, 15, 73773 Aichwald (DE). HORZER, Helen; Untere GW, KM, ML, MR, NE, SN, TD, TG). StraBe 20, 72070 Tilbingen (DE). SCHOOR, Oliver; Published: Eichhaldenstrasse 19, 72074 Tibingen FRITSCHE, (DE). — 21(3)) Jens; Larchenweg 11, 72144 Dusslingen SINGH, with international search report (Art (DE). Harpreet; 2215 Dryden Rd, Houston, Texas 77030 (US). — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of Agent: KRAUSS, B.; Boehmert Boehmert, Petten- (74) Jan & 48.2(h)) amendments (Rule koferstraBe 20-22, 80336 Miinchen (DE). — with sequence listing part of description (Rule 5.2(a)) 1-1 .4t in i t M GC o (54) Title: PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST BREAST CANCER - AND OTHER CANCERS I N (57) : The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In 1-1 c:::, particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associ - el ated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active phar- 0 maceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.