baber/WOPTO huggingface dataset:
Patent EA-018453-B1 (EA)
Title: Human monoclonal antibodies to activin receptor-like kinase-1 and use thereof
Inventor: NORTH MICHAEL AIDAN
IPC: A61K39/395
Filed: 2006-09-06
Abstract: The present invention relates to antibodies including human antibodies and antigen-binding portions thereof that bind to the extracellular doman (ECD) of activin receptor-like kinase-1 (ALK-1) and that function to abrogate the ALK-1/TGF-beta-1/Smad1 signaling pathway. The invention also relates to heavy and light chain immunoglobulins derived from human anti-ALK-1 antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to methods of making human anti-ALK-1 antibodies, compositions comprising these antibodies and methods of using the antibodies and compositions.
Patent EA-015687-B1 (EA)
Title: Polymorphs
Inventor: SIEGER PETER
IPC: A61K31/522
Filed: 2007-04-30
Abstract: The invention relates to polymorphic crystal modifications of 1-[(4-methylquinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-(3-(R)-aminopiperidin-1-yl)xanthine, their production and their use for the preparation of a drug.
Patent EA-021923-B1 (EA)
Title: Two-part sealant composition for insulating glass structure, process for forming a cured sealant composition for insulating glass structure, cured sealant composition obtainable by said process, use of such composition in a structure, comprising insulating glass structure, window or door, comprising cured sealant composition
Inventor: HUDSON JOHN MICHAEL
IPC: C09K3/10
Filed: 2008-11-07
Abstract: A two-part sealant composition for insulating glass structures, comprising a first part and a second part. The first part comprises a polymer selected from silane-terminated polyurethanes and silane-terminated polyethers, wherein this polymer is telechelic with di- or tri-functional end-groups which are alkoxy groups and wherein the polymer is present in an amount of up to 100% by weight of the first part of the sealant composition. The second part comprises a plasticiser that is compatible with the polymer and a filler comprising at least 0.5% by weight of residual water, wherein the filler comprises at least one rheological filler, and wherein the filler is present in an amount of 20-80% by weight of the second part of the sealant composition. The first and second parts are separated from one another, and the amount of polymer present in the first part makes up 4-50% by weight of the first and second parts taken together. In use, the first and second parts are mixed to achieve a cured substance having a 48 hour Shore A hardness in the range of 25-70.
Patent EA-018634-B1 (EA)
Title: And method of manufacturing a disposable diaper
Inventor: TAKINO SHUNSUKE
IPC: A61F13/15
Filed: 2008-09-03
Abstract: The aim of the invention is a method of manufacturing a disposable diaper in which the position of an absorption core does not become misaligned from the center of a pair of leg elastic members. The method includes a sheet member manufacturing process (P1), a joining process (P2), and a cutting process (P3). In the sheet member manufacturing process (P1), elastic members are joined, while being stretched, to sheets continuously supplied in the machine direction (MD), and this forms belly side and back side sheet members (20, 30). In the joining process (P2), absorptive panels (4) are joined to the belly side and back side sheet members (20, 30) at constant intervals. Each absorptive panel (4) has a pair of crotch elastic members (42) mounted, while being stretched, on the absorptive panel (4) so as to extend along opposite long sides of a rectangular shape of the absorptive panel (4), and also has the absorption core (5) joined to the absorptive panel (4) so as to be symmetrical about an imaginary center line bisecting the distance between the pair of crotch elastic members. In the cutting process (P3), the belly side and back side sheets to which the absorptive panels are joined are cut.
Patent EA-027969-B1 (EA)
Title: Soap bar composition
Inventor: AGARKHED AJIT MANOHAR
IPC: C11D9/26
Filed: 2013-03-05
Abstract: The present invention relates to a substantially transparent soap bar composition that provides high visual appeal and other sensory attributes of such compositions. Additionally it provides enhanced germ reduction benefits. The described composition comprises 30 to 60% of total fatty matter; 20 to 50% of a polyhydric alcohol; 0.01 to 5% terpineol; 0.01 to 5% thymol; and 5 to 25% water by weight of the composition.
Patent EA-023520-B1 (EA)
Title: Method for manufacturing a non-slip glass sheet
Inventor: DENEIL CHRISTINE
IPC: C03C19/00
Filed: 2012-06-20
Abstract: The invention relates to a method for manufacturing a glass sheet having non-slip properties, wherein a portion of one of the surfaces of the sheet is textured. The invention particularly relates to a method for manufacturing a textured glass sheet having non-slip properties, comprising the following consecutive steps: a) a step of texturing the entirety of a surface of a glass sheet; b) a selective protection step during which a portion of the textured surface of the sheet is protected by a protective layer; c) a smoothing step during which the textured areas of the surface not protected by the protective layer are re-smoothed; and d) a finishing step during which the protective layer is removed.
Patent EA-033285-B1 (EA)
Title: Axmi205 variant proteins and methods for their use
Inventor: HIENRICHS VOLKER
IPC: A01N63/50
Filed: 2012-07-27
Abstract: Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for pesticidal polypeptides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated pesticidal nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:7, 8, 9, 10, 11 or 12, the nucleotide sequence set forth in SEQ ID NO:4, 5 or 6, as well as variants and fragments thereof.
Patent EA-033614-B1 (EA)
Title: Cylodextrin complexation methods for formulating peptide proteasome inhibitors
Inventor: LEWIS EVAN
IPC: A61K47/40
Filed: 2013-05-08
Abstract: This invention relates to a method for preparing a pharmaceutical composition comprising the following steps: (i) mixing (a) a compoundor a pharmaceutically acceptable salt thereof; (b) a cyclodextrin containing less than 0.05% w/w sodium chloride (a low chloride cyclodextrin); and (c) water; to form a first combination that is heterogeneous; (ii) contacting the first combination with an organic acid to form a second combination; (iii) mixing the second combination to form a homogeneous third combination; (iv) optionally, sterile filtering the third combination; and lyophilizing the third combination to provide a lyophilizate. Such methods substantially increase the solubility and stability of these proteasome inhibitors and facilitate both their manufacture and administration.
Patent EA-029498-B1 (EA)
Title: ANTI-TUMOUR DRUG BASED ON RECOMBINANT INTERFERON ALPHA-2b IN THE FORM OF MICROPARTICLES FOR PARENTERAL ADMINISTRATION
Inventor: YURKSHTOVICH TATYANA LUKINICHNA
IPC: A61K47/12
Filed: 2015-11-24
Abstract: The invention is related to the field of biotechnology, in particular, to an anti-tumour drug based on recombinant interferon alpha-2b in the form of microparticles, and can be used in medicine. The objective of the invention is producing a novel antitumour drug based on recombinant interferon alpha-2b in the form of microparticles for parenteral administration that provides a stronger anti-tumour effect. Said objective is attained by provision of an anti-tumour drug based on recombinant interferon alpha-2b in the form of microparticles for parenteral administration comprising recombinant interferon alpha-2b, sodium acetate, sodium chloride, ethylene diamine tetracidic acid, d-mannitol and Tween 20, and including microgels of starch phosphate or dextran phosphate as microparticles, the drug being a lyophilisate with the following contents of components in the lyophilisate, mg: recombinant interferon alpha-2b - 10-2∙10IU, starch phosphate or dextran phosphate - 5-10, d-mannitol - 10-20, sodium chloride - 0.001-5.8, sodium acetate - 0-1.6, ethylene diamine tetracidic acid - 0.008-84.1, Tween® 20 - 0-0.1.
Patent EA-033489-B1 (EA)
Title: Wind power plant
Inventor: SHAMSIDINOV DZHUMABOJ
IPC: F03D3/04
Filed: 2016-03-09
Abstract: The invention relates to the field of wind power generation and can be utilized to build small- and mid-size wind power stations. The invention can be utilized in any areas where wind flows are present and enables a significant increase of plant power output due to its higher efficiency factor and effective use of wind flows. The power station casing consists of two identical hollow spheres with truncated upper parts, joined together at their wider side. There are louvres covering the openings of the streamlined spherical surface that may only be opened inside the casing, the wind flowing through them and embracing a cross section area that is significantly larger than the circle contour made by rotor blades; wind flows penetrate inside the spheres, get accumulated and directed towards the nozzle with propeller blades positioned at the upper truncated part of the cone where they rotate the blades while exiting the cone. No change of wind direction affects the operation of the power plant, since every time the louvres facing the wind flow get opened while other louvres are shut closed to rest on their stoppers by air building up the pressure inside the casing of the power station.
Patent EA-034350-B1 (EA)
Title: Interleukin-2 fusion proteins and uses thereof
Inventor: KLEIN CHRISTIAN
IPC: C07K19/00
Filed: 2015-02-04
Abstract: The present invention generally relates to fusion proteins of immunoglobulins and interleukin-2 (IL-2). More particularly, the invention concerns fusion proteins of immunoglobulins and mutant IL-2 that exhibit improved properties for use as therapeutic agents, e.g. in the treatment of autoimmune diseases and immune-mediated inflammatory diseases. In addition, the present invention relates to polynucleotides encoding such fusion proteins, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the fusion proteins of the invention, and to methods of using them in the treatment of disease.
Patent EA-032717-B1 (EA)
Title: Homogeneous formulation for oral administration comprising omega-3 polyunsatured fatty acids and resveratrol
Inventor: GIANNINI GIUSEPPE
IPC: A61K47/24
Filed: 2015-03-26
Abstract: The present invention relates to homogeneous formulations for oral administration comprising omega-3 polyunsaturated fatty acids (n-3 PUFA) and resveratrol, wherein, to obtain the formulation, the resveratrol is solubilized in a solvent system consisting of omega-3 polyunsaturated fatty acids (n-3 PUFA), or their alkyl esters, and a ionic emulsifier. The composition according to the present invention can be formulated as food or nutritional supplement or medicament in the prevention or treatment of cardiovascular diseases due to lipid metabolism disorders and increased platelets aggregation, as well as damages due to free radicals and/or viral diseases.
Patent EA-033482-B1 (EA)
Title: Modular buoyancy system and flotation element for net cage
Inventor: NAESS ANDERS
IPC: A01K61/00
Filed: 2015-09-08
Abstract: A buoyancy element (1) for constructing a modular buoyancy system (2) for a circularly shaped net cage (3), the buoyancy element (1) including a cage side (11), an opposite straight long side (13), coupling sides (15, 17) between the cage side (11) and the straight long side (13), and the cage side (11) being curved, following the periphery of the net cage (3).
Patent EA-036294-B1 (EA)
Title: Method for separate-suckling raising of medium-wool lambs
Inventor: KAZIKHANOV RASHIT
IPC: A01K67/02
Filed: 2017-12-11
Abstract: The invention relates to agriculture and can be used in livestock, in particular, in lamb raising. The technical objective of the invention is provision of organized, targeted, differentiated by periods raising of lambs in order to realize their genetic potential to a maximum possible extent according to the principle of technological stream-lining of production cycles with a certain sequence: during critical periods of life, from the moment of birth to 3 weeks of age, lambs are grown in small drop herds together with dams; then, from 3 weeks to 1.5 months of age, the lambs are raised with 2-fold access to dams every 2 hours before the 12 o'clock watering with extra nutrition with barley stock feed at a rate of 0.1 kg per head, and from 1.5 to 4 months of age or until ablactation the lambs are grown in large drop herds with one-time access of lambs to dams before the 12 o'clock watering, with an increase in extra nutrition with barley stock feed from 0.2 kg per head for 2-month-old lambs and up to 0.4 kg per head by 4 months of age, gradually increasing the weight of the extra nutrition as the live weight of the lambs increases, and at noon, from 16 hours the lambs are grazed with dams in pasture, leaving them with dams at night time.
Patent EA-039168-B1 (EA)
Title: Set of panels to obtain a furniture product
Inventor: BOO CHRISTIAN
Filed: 2017-01-25
Abstract: A set of panels includes a first panel 2 with a first main plane and a second panel 4 with a second main plane. The first and the second panel are provided with a mechanical locking device for locking a first edge of the first panel 2 to a second edge of the second panel 4 at a junction plane J, wherein the first main plane is essentially perpendicular to the second main plane and the junction plane is extending between the first main plane and the second main plane. The first edge includes an edge tongue 22 that extends from the junction plane. The second edge includes an edge groove 21 at the junction plane. The edge tongue is configured to cooperate with the edge groove for locking together the first and the second edges in a first direction D1 which is perpendicular to the first main plane. The edge tongue 22 includes a tongue groove 10. The edge groove 21 includes a flexible tongue 30 arranged in an insertion groove 20. Said flexible tongue is configured to cooperate with the tongue groove 10 for locking together the first and the second edges in a second direction D2 which is perpendicular to the second main plane. The mechanical locking device comprises a first space 46 between the edge tongue 22 and the edge groove 21 at an opening of the edge groove 21 and at the junction plane in a locked position of the first and the second edges.
Patent EA-035681-B1 (EA)
Title: Method for copper-electrolyte slime processing
Inventor: TABETOV BOLAT ZHOLDYBAEVICH
IPC: C25C1/12
Filed: 2019-05-08
Abstract: The present invention relates to pyrometallurgy of non-ferrous metals and can be used for processing copper-electrolyte slimes obtained as a result of processing copper scrap and waste containing non-ferrous and precious metals. The technical result is increased integration of utilization and processing of secondary copper scrap, an increased degree of extraction of copper and precious metals from secondary copper-containing scrap. This is achieved by provision of a method for processing copper electrolyte slimes comprising, according to the invention, removal of copper from the slime to its residual content in the slime of 2.5-3.0%, removal of sulfur from the slime to its residual content of not more than 2.0%, and mixing the slime with sodium carbonate and a carbonaceous reducing agent, followed by pelletizing the loose dusty slime into 25-35 mm pellets of burden, melting the burden granules in reverberatory furnace at a temperature of 800-900°C, followed by pouring of the lead-silver-gold alloy into ingots. The novelty is that copper-electrolyte slimes containing precious metals produced as a result of processing of secondary copper-containing scrap are an independent input product for further production and obtaining a metal alloy collecting gold and silver.
Patent ES-2204267-B1 (ES)
Title: Dispositivo para la fijacion de protesis dentales.
Inventor: RIDAO DALMAU MARCELA
IPC: A61C8/00
Filed: 2002-01-17
Granted: 2005-03-01
Abstract: Dispositivo para la fijación de prótesis dentales. El dispositivo comprende un cuerpo con rosca exterior, incorporable al hueso maxilar, que por su parte superior presenta un alojamiento para recibir un tornillo de fijación de la base portadora del implante, en el que el alojamiento superior tiene su superficie interna en forma de prisma recto rectangular dodecágonal, con un cono de entrada en su borde superior.
Patent ES-2190770-B1 (ES)
Title: Procedimiento para realizar fotografias.
Inventor: MARIN LACUEVA ALFONSO
IPC: F21S8/00
Filed: 2002-01-24
Granted: 2004-06-01
Abstract: Procedimiento para realizar fotografías. Consiste en que se realizan las siguientes etapas: a) Colocar una cámara fotográfica en un espacio en la oscuridad. b) Abrir el obturador de la cámara fotográfica. c) Iluminar al menos una parte del espacio (1 a 10) con al menos una fuente de luz móvil durante un periodo de tiempo determinado. d) Cerrar el obturador de la cámara fotográfica. Mientras el obturador está abierto, se va registrando en la película fotográfica las diferentes iluminaciones realizadas con la al menos una fuente de luz móvil sobre uno o diferentes objetos en la oscuridad que desean plasmar en la fotografía.
Patent ES-2245247-B1 (ES)
Title: Metodo y dispositivo para la comparticion de informacion entre parcelas de memoria de entornos de recursos limitados.
Inventor: CANIS ROBLES JAVIER
IPC: G07F7/10
Filed: 2004-06-09
Granted: 2006-12-16
Abstract: Método y dispositivo para la compartición de información entre parcelas de memoria de entornos de recursos limitados. La presente invención está relacionada con la gestión de información tal y como datos y/o procedimientos residentes en memoria en sistemas con capacidad de procesamiento y almacenamiento reducidos, como por ejemplo los existentes en una tarjeta inteligente. Un método y un dispositivo según la invención permiten que diversas aplicaciones residentes en parcelas de memoria distintas, puedan compartir los datos y/o procedimientos, de manera segura y haciendo un uso óptimo de la capacidad de procesado del sistema al que pertenece la memoria. Un mecanismo de compartición estricto permite asegurar que si una aplicación ha obtenido un dato o procedimiento de otra aplicación o del propio sistema en el que reside el mecanismo, es porque está autorizada a usarlo y por lo tanto no es necesario realizar ninguna verificación. El mecanismo de compartición está basado en que los datos y procedimientos de una aplicación solo pueden ser referenciados por otra durante su ejecución y a través de unos mecanismos de compartición definidos en la presente invención.
Patent ES-2235674-B1 (ES)
Title: Escalera compensada de peldaños modulares.
Inventor: BALAGUER SALVADOR RICARDO
IPC: E04F11/09
Filed: 2005-04-11
Granted: 2006-02-16
Abstract: Escalera compensada de peldaños modulares. Comprende una pluralidad de peldaños idénticos formados por una zona rómbica plana, una espalda triangular angular, una columna cilíndrica vertical y un soporte inferior en forma de L, con solapas laterales de refuerzo. Los peldaños se acoplan mediante tornillos y por superposición de sus columnas verticales y los soportes en forma de L, con desviaciones angulares entre cada par de peldaños determinadas, en las zonas curvilíneas de la escalera, por entrantes y salientes diametrales en las zonas de superposición.
Patent ES-2276628-B1 (ES)
Title: Dispositivo de captura de datos biometricos.
Inventor: LUCAS GOMEZ ANGEL
IPC: G06K9/00
Filed: 2005-12-15
Granted: 2008-06-16
Abstract: Dispositivo de captura de datos biométricos personales en presencia de un agente encargado de la captura, que comprende, por un lado, una pluralidad de equipos de captura de datos destinados a ser operados por el sujeto de la captura, tales como un lector de huellas (19) y un teclado (15) y, por un lado enfrentado al anterior, por una pluralidad de equipos de captura de datos destinados a ser operados por el agente encargado de la captura, tales como un escáner (11) y un lector de tarjetas (13).
Patent ES-2285953-B1 (ES)
Title: "sistema de puerta automatica con banda de seguridad y procedimiento que ejecuta dicho sistema".
Inventor: RENALIAS ZUERAS RICARD
IPC: E05F15/00
Filed: 2007-02-01
Granted: 2008-09-01
Abstract: Sistema de puerta automática con banda de seguridad y procedimiento que ejecuta dicho sistema. Sistema de puerta automática con banda de seguridad, que comprende: - una puerta automática dotada de un motor; - una banda de seguridad situado en un extremo móvil de la puerta; - al menos un dispositivo emisor de radiofrecuencia, situado en una parte móvil de la puerta; - un receptor fijo de radiofrecuencia; - un dispositivo de control del motor conectado al receptor fijo de radiofrecuencia; caracterizado porque: - el emisor dispone de medios para pasar a un estado secundario de menor consumo de energía o estado durmiente, de un receptor de radiofrecuencia y de medios para pasar del estado secundario a un estado principal; - el receptor fijo dispone de un emisor fijo de radiofrecuencia, de medios para requerir del emisor o emisores un envío de señal de estado y de medios de bloqueo en función del estado del emisor o emisores.
Patent ES-2345584-B1 (ES)
Title: Superficie de control de aeronave.
Inventor: VERDE PRECKLER JORGE PABLO
IPC: B64C9/02
Filed: 2007-12-21
Granted: 2011-07-18
Abstract: Superficie de control de aeronave. 
     La invención se refiere a una superficie de
control (3) para superficie aerodinámica sustentadora (2) de
aeronave que comprende una costilla (9) de cierre principal situada
en un extremo de la superficie de control (3) a la que va unida una
barra de torsión principal (8), estando la citada barra de torsión
(8) unida en su otro extremo a un sistema de palancas (14) sobre el
que actúa al menos un actuador (15), de tal forma que se pueda
actuar sobre el giro de la citada superficie de control (3) durante
el vuelo de la aeronave. La invención se refiere también a un método
de actuación de una superficie de control (3) tal.
Patent ES-2334625-B1 (ES)
Title: Composicion para la elaboracion de un licor cremoso de limon 100% natural y artesanal.
Inventor: FIORI MARIA PIA
IPC: C12G3/06
Filed: 2008-06-03
Granted: 2011-01-28
Abstract: Composición para la elaboración de un licor
cremoso de limón 100% natural y artesanal, es una bebida alcohólica
sin conservantes. Contiene una fórmula donde se mezcla primero la
corteza de los limones con el alcohol por un determinado tiempo,
pasado ese tiempo por otro lado se mezcla la leche con el azúcar,
luego se agrega la nata y por último el alcohol ya filtrado, sin la
corteza. Se obtiene un líquido el cual se embotellará y se
conservará siempre en el congelador.
Patent ES-2331284-B1 (ES)
Title: Materiales nanocompuestos con actividad antimicrobiana y el procedimiento para su obtencion.
Inventor: LAGARON CABELLO JOSE MARIA
IPC: C08K3/10
Filed: 2008-06-25
Granted: 2010-09-30
Abstract: Materiales nanocompuestos con actividad
antimicrobiana y el procedimiento  para su obtención. La presente
invención se refiere a nuevos materiales  nanocompuestos con
actividad antimicrobiana, que comprenden una matriz  y nanoaditivos.
Además la presente invención describe un procedimiento  para la
obtención de dichos materiales nanocompuestos y el uso de los mismos
 en distintos sectores de la industria.