baber/WOPTO huggingface dataset:
Patent JP-3519736-B2 (JP)
IPC: A61K31/505
Filed: 1993-08-25
Granted: 2004-04-19
Abstract: A method and composition for the treatment of humans infected with HIV that includes administration of an HIV treatment amount of an enantiomerically pure  beta -D-dioxolanyl purine nucleoside of formula (I), wherein R is OH, Cl, NH2, or H, or a pharmaceutically acceptable salt or derivative of the compound, optionally in a pharmaceutically acceptable carrier or diluent.  <CHEM>   <IMAGE> <IMAGE>
Patent JP-3760210-B2 (JP)
IPC: B05C11/02
Filed: 1996-08-09
Granted: 2006-03-29
Abstract: There is disclosed a method for applying sealant material between spaced-apart substrates in an insulated glass assembly. The method is sequential and employs extrusion nozzles and smoothing plates. The smoothing plates move in concert with the extrusion nozzles to ensure uniform distribution of the sealant material from the spacer, spacing the substrates, to the perimeter of the substrates. The smoothing plates ensure a uniform and planar surface at the perimeter. The method of operation is automated and accordingly, the sealant can be applied in an expedited manner with a high degree of precision and uniformity.
Patent JP-3352088-B2 (JP)
IPC: B30B1/32
Filed: 1992-04-22
Granted: 2002-12-03
Abstract: PCT No. PCT/EP92/00891 Sec. 371 Date Feb. 22, 1993 Sec. 102(e) Date Feb. 22, 1993 PCT Filed Apr. 22, 1992 PCT Pub. No. WO92/18264 PCT Pub. Date Oct. 29, 1992.Method and Apparatus for carrying out an operation, such as pressing, riveting, cutting, etc., on a mechanical workpiece which operation comprises at least one stroke, or movement, along a predetermined path, of at least two active members (6,7) each being arranged on a carrying unit (1,2). The mechanical workpiece is first positioned between the active members (6,7). Thereafter the carrying units (1,2) for the active members are approached to each other in a first part of the stroke. The carrying units (1,2) are then locked to each other at the end of said first part of said stroke and a second part of said stroke is carried out by way of the relative movement between the active members (6,7) to achieve the desired effect on the said workpiece.
Patent JP-2860603-B2 (JP)
IPC: A61P9/12
Filed: 1994-07-04
Granted: 1999-02-24
Abstract: wherein A, B, D, E, and F are each independently nitrogen or carbon; R1 is hydrogen, C1 to C6 alkyl, -(CH2)nR7, or C1 to C3 alkyl-aryl; R2, R3, R4, R5 and R6 are each independently hydrogen, C1 to C6 alkyl, aryl, C1 to C3 alkyl-aryl, halogen, cyano, nitro, -(CH2)mNR8R9, -(CH2)mOR9, -SR8, -SO2NR8R9, -(CH2)mNR8SO2R9, -(CH2)mNR8CO2R9, -(CH2)mNR8COR9, -(CH2)mCONR7R9, or -(CH2)mCO2R9; R2 and R3, R3 and R4, R4 and R5, and R5 and R6 may be taken together to form a five- to seven-membered alkyl ring, a six-membered ary ring, a five- to seven-membered heteroalkyl ring, having 1 heteroatom of N, O, or S, or a five- to six-membered heteroaryl ring having 1 or 2 heteroatoms of N, O, or S; R7is -OR10, -SR10, -SO2NR10R11, -NR10SO2R11, -NR10CO2R11, -NR10COR11, -CONR10R11, or -CO2R10; R8, R9, R10 and R11 are each independently hydrogen, C1 to C6alkyl, or C1 to C3 alkyl-aryl; m is 0, 1, or 2; n is 2, 3, or 4; and the above aryl groups and the aryl moieties of the above alkyl-aryl groups are each independently phenyl or substituted phenyl, wherein said substituted phenyl may be substituted with one to three of C1 to C4 alkyl, halogen, hydroxy, cyano, carboxamido, nitro, or C1 to C4 alkoxy, and the pharmaceutically acceptable salts thereof. These compounds are useful in treating migraine and other disorders and are new. These compounds are useful psychotherapeutics and are potent serotonin (5-HT1) agonists and may be used in the treatment of depression, anxiety, eating disorders, obesity, drug abuse, cluster headache, migraine, pain, and chronic paroxysmal hemicrania and headache associated with vascular disorders, and other disorders arising from deficient serotonergic neurotransmission. The compounds can also be used as centrally acting antihypertensives and vasodilators.
Patent JP-3332377-B2 (JP)
IPC: A61P35/00
Filed: 1990-07-05
Granted: 2002-10-07
Abstract: A therapeutic combination, useful in the treatment or prevention of benign prostatic hyperplasia, includes an antiestrogen and at least one further active ingredient selected from the group consisting of inhibitors of aromatase activity and inhibitors of 5 alpha -reductase activity. Pharmaceutical compositions and kits useful for such treatment are also provided.
Patent JP-3339053-B2 (JP)
IPC: E04B9/02
Filed: 1997-08-06
Granted: 2002-10-28
Abstract: A filter medium with excellent flame-resistant properties and an air filter unit using the same are provided which have a flame-resistant air permeable supporting material on at least one surface of a polytetrafluoroethylene (PTFE) porous film and which can be used as a ceiling device, etc. <IMAGE>
Patent JP-2803908-B2 (JP)
IPC: C07D205/08
Filed: 1994-09-14
Granted: 1998-09-24
Abstract: Hydroxy-substd. azetidinone derivs. of formula (I) and their salts are new. Ar1,Ar2 = aryl (opt. substd. by 1-5 gps. R4); Ar3 = aryl (opt. substd. by 1-5 gps. R5); X, Y, Z = CH2, CH(1-6C alkyl) or C(di(1-6C alkyl); R, R2 = OR6, OCOR6, OCOOR9 or OCONR6R7; R1, R3 = H, 1-6C alkyl or aryl; q, r = 0 or 1; m, n, p = 0-4, provided that i) at least one of q and r is 1, and the sum of m, n q and r is 1-6, and ii) when p is 0 and r is 1, the sum of m, q and n is 1-5; R4 = 1-6C alkyl, OR6, OCOR6, OCOR9, O(CH2)sOR6, OCONR6R7, NR6R7, NR6COR7, NR6COOR9, NR9, NR6CONR7R8, NR6CONR7R8, NR6SO2R9, COOR6, CONR6R7, COR6, SO2NR6R7, S(O)tR9, O(CH2)uCOOR6, O(CH2)uCONR6R7, lower alkylCOOR6, CH=CH-COOR6, CF3, CN, NO2 or halogen; R5 = OR6, OCOR6, O(CO)R9, O(CH2)vOR6, -O(CO)NR6R7, NR6R7, NR6COR7, NR6COOR9, NR6COOR9, NR6CONR7R8, NR6SO2R9, COOR6, CONR6R7, COR6, SO2NR6R7, S(O)tR9, -O(CH2)uCOOR6, O(CH2)uCONR6R7, lower alkylCOOR6 or -CH=CH-COOR6; s = 1-5; t = 0-2; u = 1-10; v = 1-5; R6, R7, R8 = H, 1-6C alkyl (opt.substd. with aryl) or aryl; and R9 = 1-6C alkyl (opt. substd. with aryl) or aryl.
Patent JP-2851422-B2 (JP)
IPC: A61K47/26
Filed: 1990-06-29
Granted: 1999-01-27
Abstract: PCT No. PCT/FR90/00484 Sec. 371 Date Feb. 28, 1992 Sec. 102(e) Date Feb. 28, 1992 PCT Filed Jun. 29, 1990 PCT Pub. No. WO91/00106 PCT Pub. Date Jan. 10, 1991.The present invention relates to injectable multi-phase solutions of W/O/W type, usable as vaccines or as vehicles of active substances in human and veterinary medicine, which are pharmaceutically acceptable in each one of their constituents, stable for at least 12 months in storage at 4 DEG  C., of viscosity less than 300 mPas and comprise at least the following constituents: an oily adjuvant composed of: a water-immiscible oily phase representing between 20 and 70% of the formula, an emulsifying system selected so that the inversion point of the resulting emulsion ranges between 25 DEG  and 45 DEG  and represents between 2 and 10% of the formula, an aqueous phase containing the antigens or the active substances and representing between 20 and 78% of the formula and obtained in a single mixing operation.
Patent JP-4176145-B2 (JP)
IPC: D21H13/24
Filed: 1994-10-20
Granted: 2008-11-05
Abstract: Thermally bonded absorbent structures for catamenial products, in particular catamenial pads, that provide improved ability in acquiring, distributing and storing aqueous body fluids, especially menstrual fluids, as well as better fit and comfort for the user of the products. These structures comprise an optional thermally bonded secondary topsheet, a thermally bonded absorbent core having a relatively higher capillary suction primary fluid distribution layer, an optional but preferred relatively lower capillary suction secondary distribution layer, a storage layer having absorbent gelling material, and an optional fibrous "dusting" layer. These thermally bonded absorbent structures are particularly useful with catamenial pads having a primary fluid pervious topsheet selected from apertured formed film topsheets and high loft nonwoven topsheets.
Patent JP-3847784-B2 (JP)
IPC: H01H50/02
Filed: 1996-03-05
Granted: 2006-11-22
Abstract: PCT No. PCT/DE96/00385 Sec. 371 Date Sep. 19, 1997 Sec. 102(e) Date Sep. 19, 1997 PCT Filed Mar. 5, 1996 PCT Pub. No. WO96/29720 PCT Pub. Date Sep. 26, 1996In the case of the relay, an insulating wall which has at least three insulating layers is formed between the magnet system and a live metal part, in that the insulating wall is formed from a wall base having at least one insulating gap, and in that the insulating layer is formed in the insulating gap by insulating material which is inserted in liquid form and is subsequently cured.
Patent JP-3959531-B2 (JP)
IPC: A63H3/48
Filed: 1997-12-09
Granted: 2007-08-15
Abstract: The invention relates to a mechanical model of an animal, especially a toy dog with forelegs and hind legs which are pivotally arranged around a first pivot with a rotation axis perpendicular to the direction of movement of the animal model, wherein the forelegs are articulated by a first drive mechanism with a first gear unit and a first drive axis. Said arrangement is configured in such a way that at least one hind leg is pivotally arranged around a second pivot, wherein the rotation axes of the hind leg are tilted in relation to each other at a given angle and a second drive mechanism is provided for selectable movement of the hind leg around the second pivot.
Patent JP-4346692-B2 (JP)
IPC: C07C403/00
Filed: 1998-04-29
Granted: 2009-10-21
Abstract: A process for the isolation of crystalline carotenoid compound from microbial biomass comprising disrupting the microbial cell walls, separating cellular debris from the carotenoid-containing residue, washing one member of the group consisting of the microbial biomass, the disrupted cell mass and the carotenoid-containing reside with a solvent to remove lipid, suspending the obtained carotenoid crystals in water to float the crystals, recovering the crystals and, optionally, further purifying the crystals which avoids the use of large amounts of solvent of carotenoid extraction process.
Patent ES-2183718-B2 (ES)
Title: Nuevo procedimiento para la preparacion de hidroxiarilglicinas, alcoxiarilglicinas y sus glicinatos.
Inventor: SIERRA RODRIGUEZ MIGUEL ANGEL
IPC: C07C229/36
Filed: 2001-06-14
Granted: 2004-03-16
Abstract: Nuevo procedimiento para la preparación de hidroxiarilglicinas, alcoxiarilglicinas y sus glicinatos. La presente invención consiste en un nuevo procedimiento para sintetizar hidroxiarilglicinas, alcoxiarilglicinas y sus glicinatos químicamente puros y con buenos rendimientos. Estos compuestos son muy interesantes como precursores para la obtención de productos farmacéuticos y agroquímicos.
Patent ES-2215492-B2 (ES)
Title: Amortiguador acustico regulable.
Inventor: MUNOZ MOLINA JUAN
IPC: E04F15/22
Filed: 2004-05-13
Granted: 2005-05-01
Abstract: Amortiguador acústico regulable, de especial utilización en la construcción para la realización de suelos flotantes de hormigón y bancadas ajustables, minimizando los efectos acústicos y vibraciones que puedan generarse, caracterizado principalmente por una base metálica y un silentblock de caucho, una vez atornillados y regulados en altura, se instala sobre ellos un panel hidrófugo constitutivo de base para la colocación de un mallazo, sobre el cual se vierte el hormigón constituyéndose un suelo flotante. La invención que se presenta aporta las principales ventajas de proporcionar un mayor aislamiento acústico, evitando las vibraciones que pueden generarse, a la par que proporciona una mejor adaptabilidad al suelo.
Patent ES-2371879-B2 (ES)
Title: Concentrador de radiación hiperbólico parabólico.
Inventor: GARCIA BOTELLA ANGEL
IPC: F24S23/70
Filed: 2008-10-10
Granted: 2012-06-07
Abstract: Concentrador de radiación hiperbólico parabólico, que comprende una superficie que está generada a partir de un perfil geométrico en dos dimensiones, obtenido de las líneas de flujo, o parte de las mismas, producidas por una fuente de luz Lambertiana que tiene forma de cuña infinita seccionada en su vértice y que no pasen por los vértices de la cuña.#El componente de la invención es especialmente aplicable como concentrador de radiaciones solares.
Patent ES-2379058-B2 (ES)
Title: Dispositivo acoplador de guías de onda, y método de diseño de dicho dispositivo
Inventor: HALIR ROBERT
IPC: G02B6/34
Filed: 2012-02-23
Granted: 2012-10-01
Abstract: Dispositivo acoplador de guías de onda, y método de diseño de dicho dispositivo.#Permite aumentar el ancho de banda del dispositivo, sin que ello suponga un aumento de sus dimensiones, y sin que su repuesta en fase se degrade. El dispositivo acoplador (1) destaca por presentar en su zona de acoplamiento (30) al menos red (31) con un periodo ({lm}) tal que garantice que no se producen fenómenos de difracción, estando dicha red (31) configurada para modificar la variación de las constantes de propagación ({be,1}, {be,2}) de los modos de primer y segundo orden ({hi,1}, {hi,2}) de la zona de acoplamiento (30) respecto a la longitud de onda, de manera que se reduce la variación de la longitud de batido (L{pi}) con la longitud de onda, aumentando así el ancho de banda del dispositivo acoplador (1).
Patent AU-2001258341-B2 (AU)
Title: 8beta-hydrocarbyl-substituted estratrienes for use as selective estrogens
Inventor: HEGELE-HARTUNG CHRISTA
IPC: A61P25/00
Filed: 2001-04-12
Granted: 2007-03-15
Abstract: This invention describes the new 8beta-substituted estratrienes of general formula I in which R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>6</SUP>, R<SUP>6'</SUP>, R<SUP>7</SUP>, R<SUP>7'</SUP>, R<SUP>9</SUP>, R<SUP>11</SUP>, R<SUP>11'</SUP>, R<SUP>12</SUP>, R<SUP>14</SUP>, R<SUP>15</SUP>, R<SUP>15'</SUP>, R<SUP>16</SUP>, R<SUP>16'</SUP>, R<SUP>17</SUP>, R<SUP>17'</SUP> have the meanings that are indicated in the description, and R<SUP>8 </SUP>means a straight-chain or branched-chain, optionally partially or completely halogenated alkyl or alkenyl radical with up to 5 carbon atoms, an ethinyl- or prop-1-inyl radical, as pharmaceutical active ingredients that have in vitro a higher affinity to estrogen receptor preparations of rat prostates than to estrogen receptor preparations of rat uteri and in vivo preferably a preferential action on bone rather than the uterus and/or a pronounced action with respect to stimulation of the expression of 5HT2a-receptors and 5HT2a-transporters, their production, their therapeutic use and pharmaceutical dispensing forms that contain the new compounds. The invention also describes the use of these compounds for treatment of estrogen-deficiency-induced diseases and conditions as well as the use of an 8beta-substituted estratriene structural part in the total structures of compounds that have a dissociation in favor of their estrogenic action on bones rather than the uterus.
Patent AU-2001271429-B2 (AU)
Title: Thermokinetic mixer, compositions and structural products
Inventor: GOOD ELMER
IPC: B29B7/16
Filed: 2001-06-25
Granted: 2005-06-16
Abstract: The present invention comprises a novel thermokinetic mixer. In one form of the invention, the mixing chamber shaft projections are removable at least in part and replaceable without cutting the projections from the shaft. In another form of the invention, only a tip portion of such projections are removable and replaceable without such cutting. In yet another form of the invention, shaft projections into the mixing chamber comprise a tooth having a substantially reticulated face forming a deflecting surface such that substantially all mixing chamber particles encountering the tooth strike and are deflected at an incident substantially lateral angle from the deflecting surface.
Patent AU-2002234564-B2 (AU)
Title: Template-fixed peptidomimetics as inhibitors of serine proteases
Inventor: DESCOURS ANNE
IPC: C07K7/08
Filed: 2001-12-11
Granted: 2008-11-06
Abstract: Template-fixed beta-hairpin peptidomimetics of the general formulae (I), wherein Z is a template-fixed chain of 7 to 11 alpha-amino acid residues which, depending on their positions in the chain (counted starting from the N-terminal amino acid) are Gly, or Pro, or of certain types which, as the remaining symbols in the above formulae, are defined in the description and the claims, and salts thereof, have the property to inhibit proteases, in particular serine proteases. These beta-hairpin peptidomimetics can be manufactured by a process which is based on a mixed solid- and solution phase synthetic strategy.
Patent AU-2002334929-B2 (AU)
Title: Puncturing means for use in an inhalation device
Inventor: KEVIN STAPLETON
IPC: A61M15/00
Filed: 2002-10-10
Granted: 2006-03-02
Abstract: A puncturing device (1600) for puncturing of a wall, in particular the wall of a capsule containing medication for inhalation. The puncturing device or assembly comprises one or more substantially longitudinal prongs (1620), each having a puncturing surface (1630) at its distal end as well as a primary cutting edge (1640) disposed on the periphery of the prong and terminating at the puncturing surface (1630). A substantially planar face (1650) is disposed on the periphery of each prong (1620) opposite of the primary cutting edge (1640).
Patent AU-2002340659-B2 (AU)
Title: Photodynamic therapy for the treatment of hair loss
Inventor: BOCH RONALD ERWIN
IPC: A61P43/00
Filed: 2002-11-08
Granted: 2008-04-10
Abstract: Photodynamic therapy (PDT) is used to stimulate and/or restore hair growth in areas of hair loss. Methods and compositions relating to PDT treatment for alopecia are disclosed. In light of PDT use to remove unwanted hair by inactivating or destroying hair follicles or destroying the tissue feeding the hair follicles, such methods and compositions relate to a surprising and unexpected discovery. PDT permits a means to treat conditions relating to hair loss such as androgenic alopecia, alopecia areata and drug-induced alopecia.
Patent AU-2002359152-B2 (AU)
Title: A liquid pharmaceutical formulation comprising nicotine for the administration to the oral cavity
Inventor: BERGENGREN GUNNAR
IPC: A61K9/12
Filed: 2002-12-18
Granted: 2006-11-09
Abstract: A liquid pharmaceutical formulation comprising nicotine in any form for administration to the oral cavity being alkalized by buffering and/or pH regulation. The administration is preferably by spraying and most preferably by spraying under the tongue. A method for manufacturing said formulation. Use of said formulation in therapy, such as therapy for treating addiction to tobacco.
Patent AU-2002364204-B2 (AU)
Title: Methods and apparatus for encapsulating a frame for transmission in a storage area network
Inventor: DUTT DINESH GANAPATHY
IPC: H04L29/08
Filed: 2002-12-23
Granted: 2008-04-03
Abstract: Methods and apparatus for encapsulating a packet or frame for transmission in a storage area network are disclosed. A packet or frame compatible with a standard protocol employed in the storage area network is received or generated. The packet or frame is then encapsulated with a virtual storage area network identifier. The packet or frame may further be encapsulated with at least one of a TTL value, MPLS information, and a type of traffic to be carried by the packet or frame. For instance, the type of traffic to be carried by the packet or frame may include Ethernet, Fibre Channel, and Infiniband. Once encapsulated, the encapsulated packet or frame is sent over the storage area network. For instance, the encapsulated packet or frame may be generated as well as transmitted by a switch over an inter-switch link in the storage area network.
Patent AU-2003204138-B2 (AU)
Title: Electronic Purification of Air in Tunnels
Inventor: CRAVERO HUMBERTO ALEXANDER
IPC: B03C3/12
Filed: 2003-05-07
Granted: 2013-07-18
Abstract: ELECTRONIC PURIFICATION OF AIR IN TUNNELS An assembly 10 and associated collectors 12 are installed in a tunnel 11 to remove particle pollution from air within the tunnel 11. The assembly 10 includes the 5 housing 15 through which air passes from inlets 19 to an outlet 21. At the outlet 21 an emitter 22 delivers ions to the air stream passing therethrough with the ions being attached to particles in the air in the tunnel 11, with the charged particles then being attracted to the positively charged collectors 12. ION, Is)3
Patent AU-2003248014-B2 (AU)
Title: Roll-in Cot
Inventor: CAMBRIDGE ALAN RAYMOND
IPC: A61G1/02
Filed: 2003-09-18
Granted: 2008-11-06
Abstract: A roll-in cot having a patient support attached to a wheeled transporter wherein the wheeled transporter comprises leading and trailing collapsible legs having respective proximal ends pivotally connected to a frame and distal ends including wheels wherein at least the leading or the trailing collapsible legs are operable from a locked condition by a release assembly wherein the release assembly comprises a safety and a leg release wherein one of said safety and said leg release comprises a linkage, wherein in an activated condition the linkage prevents the collapse of the collapsible legs, said linkage is connected to a touch bar disposed in front of said collapsible legs whereby engagement of the touch bar against a platform deactivates the linkage and enables the collapsible legs to be collapsed on release of the other of said safety and said leg release.
Patent AU-2003267040-B2 (AU)
Title: Cyclonic fluid separator
Inventor: WILLINK CORNELIS ANTONIE TJEEN
IPC: B04C3/00
Filed: 2003-09-02
Granted: 2006-12-21
Abstract: A cyclonic fluid separator for separating condensable, liquid and/or solid components from a fluid mixture includes an upstream fluid inlet section in which the fluid mixture is accelerated to a supersonic velocity to expand and cool the fluid mixture such that one or more condensable fluid components are liquefied and/or solidified; a downstream separation section in which condensables depleted and condensables enriched fluid fractions are separated and fed into separate outlets; and a midstream vortex generation section which includes a plurality of tilted wings of which the wing tips are located at relatively large mutual spacings and at a small spacing from the inner wall of the midstream vortex generation section such that during normal operation of the separator adjacent to the various wing tips widely spaced vortices of swirling fluid are generated in the fluid stream flowing through the housing, which vortices are still separated from each other at the entrance of the downstream separation section.
Patent AU-2003290176-B2 (AU)
Title: Anchoring device for fixing elements of a particular type on a flat surface
Inventor: ROBERT FRANCOIS
IPC: F16G11/00
Filed: 2003-11-10
Granted: 2008-12-11
Abstract: The anchoring loop (1) consists of a bundle (6) of flexible fibres on one side of a partition, having splayed ends fastened between two plates (3, 4) on the inside of the partition (2). The loop is fastened to a bush (5) and a sleeve (8) of thermo-shrink material that passes through a hole in the partition lined with a second bush (10).  The plates and layer (6a) of fibre ends are fastened together by a bonding material (7) such as a polymerizable resin, and the plate (4) facing away from the partition has drainage holes (9) for surplus bonding material.
Patent AU-2004255503-B2 (AU)
Title: Method for stabilizing a cryoprecipitate of plasmatic proteins for being subjected to a viral inactivation thermal treatment
Inventor: BEGIN EDITH
IPC: A61K38/37
Filed: 2004-07-08
Granted: 2010-12-16
Abstract: The invention relates to a method for obtaining cryoprecipitatable proteins, comprising a viral inactivation step by thermally treating a lyophilisate of these proteins, comprising, before rendering the proteins in the form of a lyophilisate, an initial addition step, to these proteins, of a stabilizing and solubilizing formulation containing a mixture consisting of arginine, at least one hydrophobic amino acid and of tribasic sodium citrate. The invention also relates to a concentrate consisting of at least one cryoprecipitable protein containing the stabilizing and solubilizing formulation introduced according to the method and being suited for therapeutic use.