baber/WOPTO huggingface dataset:
Patent CZ-304983-B6 (CZ)
Title: Preparation process and novel intermediates of elvitegravir synthesis
Inventor: RÁDL STANISLAV
IPC: C07D215/56
Filed: 2012-10-12
Abstract: In the present invention, there is disclosed a process for preparing a compound of the general formula II, comprising halogenations of 2,4-dimethoxyacetophenone of the general formula III on a core to yield a compound of the general formula IV, which provides by the reaction with dialkylcarbonates in the presence of strong bases, benzoylacetate of the general formula V, which provided by the reaction with agents of the general formula Mei2NC(ORe1)i2 or (Mei2N)i2CORe1 an intermediate of the general formula VI, which reacts with (S)-(+)-valinol to yield the compound of the general formula II.
Patent CZ-304894-B6 (CZ)
Title: Lipophilic analogs of protected aminoalkyl substituted glycines and process for their preparation
Inventor: DROŽ LADISLAV
IPC: C07C233/47
Filed: 2012-12-31
Abstract: In the present invention, there are disclosed lipophilic analogs of protected amino acids of the general formula I, in which Ri1 a Ri2 represent independently on each other groups such as H, alkyl containing 3 to 40 carbon atoms, and PG represents Fmoc, Boc or Cbz protecting group. The lipophilic analogs can be prepared by two-stage synthesis resulting from a protected N,O-ditrimethyl silyl derivative II and a corresponding fatty acylation agent III, wherein LG denotes a halogen or another activating group (reaction 1). The product of this reaction is an intermediate IV, which can be transferred by an easy hydrolysis and in dependence on reaction conditions to the substance I (reaction 2). Thus, the product I is obtained in a high yield and purity without occurrence of oligomeric and degradation side products. The preparation process of the present invention can be used for the synthesis of substances in multi-kg amounts for pharmaceutical production.
Patent CZ-304679-B6 (CZ)
Title: Deviation correction method of active magnetic bearing components and/or assembly for mounting of a rotating working means
Inventor: MORAVEC MILAN
IPC: D01H4/10
Filed: 2013-03-22
Abstract: Prior beginning of operation of an active magnetic bearing, there are determined mechanical and/or electrical and/or mounting deviations of at least one component of the active magnetic bearing assembly and/or deviations of the entire assembly of the active magnetic bearing. The determined deviations and/or correction values determined therefrom are recorded into a memory (M), which forms part of the active magnetic bearing assembly. Subsequently, these deviations and/or correction values determined therefrom and stored in the memory (M) are used for adjusting the system of determining position of the rotating working means in the active magnetic bearing during operation thereof. The active magnetic bearing for mounting a rotating working means comprises means arranged within a base body for generation of magnetic field in which the rotating working means is arranged. It further comprises position sensors (A) of the rotating working means, whereby a detector (D) of the position sensor output signal and evaluation circuits (VO) are assigned to each of the position sensors (A). The memory (M), being arranged in the active magnetic bearing assembly, stores values of production variances and/or electrical and/or mounting deviations of at least one component of the active magnetic bearing assembly and/or variances and deviations of the entire active magnetic bearing assembly and/or the memory (M) stores values of correction variables generated from such variations and deviations. T7he memory (M) is connected or it can be connected with a control system (RS) and/or detectors (D) of the output signal of the positions sensors (A) and/or with evaluation circuits (VO).
Patent CZ-304584-B6 (CZ)
Title: Process for preparing pearlescent pigment based on graphite/TiO2
Inventor: MATĚJKA VLASTIMIL
IPC: C09C1/36
Filed: 2013-10-15
Abstract: The present invention relates to a process for preparing pearlescent pigment based on graphite covered with a layer of titanium dioxide prepared from titanyl sulfate, which exhibits, in case of a suitably performed heat treatment method, a different range of coloring, and by selection of a suitable graphite particle size it can exhibit a high metallic luster. In addition, there has been determined, that the so prepared product is also electrically conducting, what significantly extends its possible use if compared with classic pearlescent pigments.
Patent CZ-308445-B6 (CZ)
Title: Device for contactless transmission of electrical energy to a rotating part
Inventor: Kavalír Tomáš
IPC: H02J50/80
Filed: 2017-09-29
Abstract: The device for the rotating parts (1) comprises a receiving part (2) and a transmitting part (3) located at the working distance. They can have at least one communication data channel. The device is adapted to transmit electrical energy through a resonant electromagnetic coupling. The receiving part (2) comprises at least one receiving antenna (4). The receiving antenna (4) has its own rectifier (5). The outputs of the rectifiers (5) are interconnected by a DC bus (6). The transmitting part (3) comprises at least one transmitting antenna (7) with a transmitter (8). The resonant electromagnetic coupling between the transmitting part (3) and the receiving part (2) is dynamic. The receiving antenna (4) is connected to the connected circuits via impedance matching (9). The orientation of the receiving antennas (4) on the rotating parts (1) is adapted to receive radial or axial electrical energy. The transmitting part (3) is placed on the moving parts (10).
Patent CZ-308120-B6 (CZ)
Title: Nutritional composition
Inventor: KRATOCHVÍL ROMAN
IPC: A23L33/185
Filed: 2018-05-25
Abstract: A nutritional composition containing protein, free amino acids, medium chain triglycerides, glucose, sucrose, isomaltulose and maltodextrin, the nutritional composition comprises 2.5 to 10.5 % by weight of protein, 5.3 to 22.0 % by weight of free amino acids, 4.5 to 9.5 % by weight of medium chain triglycerides, 6.5 to 14.5 % by weight of glucose, 9.5 to 18.5 % by weight of sucrose, 27.5 to 35.5 % by weight isomaltulose and 11.5 to 20.5 % by weight of maltodextrin based on 100% by weight of the total composition. This nutritional composition is useful in muscle tissue regeneration and / or glycemic control
Patent SK-286609-B6 (SK)
Title: N-heteroaryl-substituted spiro-(aza)cyclohexancarboxamid derivatives, method for producing thereof and intermediate, their use and pharmaceutical composition comprising said compounds
Inventor: FUKAMI TAKEHIRO
IPC: A61K31/00
Filed: 2000-08-11
Abstract: Disclosed are compounds of formula (I) wherein Ar1 represents aryl or heteroaryl which may be substituted, n represents 0 or 1, T, U, V and W represent independently nitrogen atom or optionally substituted methine group, where at least two of them represent the said methine group, X represents methine or nitrogen, Y represents optionally substituted imino or oxygen atom. Compounds of the present invention exhibit NPY antagonistic activities and are useful as agents for the treatment of various diseases related to NPY, for example, cardiovascular disorders such as hypertension, nephropathy, heart disease, vasospasm, arteriosclerosis, central nervous system disorders such as bulimia, depression, anxiety, seizure, epilepsy, dementia, pain, alcoholism, drug withdrawal, metabolic diseases such as obesity, diabetes, hormone abnormality, hypercholesterolemia, hyperlipidemia, sexual and reproductive dysfunction, gastro-intestinal disorder, respiratory disorder, inflammation or glaucoma.
Patent SK-284509-B6 (SK)
Title: A method of preparation of acidic and alkaline electrolytes on the basis of chemical additives free water and a device for their preparation
Inventor: CERVENAK JAN
IPC: C02F1/46
Filed: 2001-06-07
Abstract: Electric and magnetic field are individually or simultaneously applied to straight-line flowing water in treatment area in such a way, that the force vectors of electric field and magnetic induction affect perpendicularly the direction of water velocity vector in laminar filaments. The water is treated in a device, utilising the principle of separation of selected ions from contaminated water and their consequential implantation to pure water.
Patent CZ-299606-B6 (CZ)
Title: Process for removing water from brown coal
Inventor: BUSCHSIEWEKE Frank
IPC: C10L9/00
Filed: 2000-03-24
Abstract: The invention relates to a process for dewatering raw brown coal used as a power plant fuel for producing electric current. According to the invention, the process consists in heating the raw brown coal by introducing hot water and/or steam at a working temperature ranging from 60 to 200 degC and feeding it as coal slurry into a solid wall centrifuge (2), the working chamber of which is under a pressure corresponding to the steam pressure at the working temperature wherein water bound in the raw coal is then separated by centrifuging and discharged from the solid wall centrifuge (2) working chamber as excess to be further on used in direct or indirect pre-heating of raw coal to be dewatered.
Patent CZ-302538-B6 (CZ)
Title: System for determining a fluid light energy value for delivery to a biological fluid comprising targets
Inventor: LEE KYU HO
IPC: A61N5/06
Filed: 2000-07-07
Abstract: A fluid light energy value is amount of a light energy that is to be delivered to a fluid in order to maximize a probability that targets receive a light energy, which induces a required result. The system of the present invention is particularly suitable for phototherapy and photophoresis where it is necessary to deliver an effective amount of light energy to targets in a biological liquid.
Patent CZ-294865-B6 (CZ)
Title: Process for preparing erythromycin derivatives
Inventor: BONNET ALAIN
IPC: C07H17/08
Filed: 1996-09-10
Abstract: In the present invention, there is disclosed a process for preparing erythromycin derivatives of the general formula VI, in which Z represents a protecting group, wherein the preparation process comprises reacting the compound of the general formula I, in which Ri1 represents either a substituted alkyl containing up to 8 carbon atoms, or an optionally substituted aryl having up to 14 carbon atoms, or Ri1 denotes Rb-O-C(Ra,Rc)-, with formic acid in the presence of sodium bisulfite or sodium metabisulfite, to obtain the compound of the general formula V which is then reacted with a protection agent of the hydroxyl in position 2' to obtain the compound of the general formula IV.
Patent CZ-293901-B6 (CZ)
Title: Thienopyrimidine derivative exhibiting PDE V inhibiting activity, process for its preparation and pharmaceutical composition in which the derivative is comprised
Inventor: JONAS ROCHUS
IPC: A61K31/505
Filed: 2000-06-07
Abstract: In the present invention, there is disclosed a condensed thienopyrimidine derivative of the general formula I, in which Re1, Re2 represent independently on each other a hydrogen atom, the group A, OH, OA or Hal, X represents the group Re4, Re5 or Re6 being substituted with one group Re7, Re4 denotes a straight or branched alkylene containing 1 to 10 carbon atoms, whereby one or two CHi2 can be optionally substituted with -CH=CH-, Re5 represents cycloalkyl group having 5 to 12 carbon atoms or cycloalkylalkylene group containing 5 to 12 carbon atoms in the cycloalkyl moiety, Re6 denotes phenyl or phenylmethyl, Re7    represents COOH, COOA, CONHi2, CONHA, CON(A)i2 or CN, A denotes alkyl containing 1 to 6 carbon atoms, Hal represents fluorine, chlorine, bromine or iodine,  whereby at least one of the symbols Re1 and Re2 represents the OH group, and physiologically acceptable salts thereof are suitable as a phosphodiesterase V retarder for treating diseases of heart circulation system and further for treating potency disorders.
Patent CZ-297736-B6 (CZ)
Title: Crate for fruits or the like products
Inventor: MOSTINI SERGE
IPC: B65D1/36
Filed: 2001-12-20
Abstract: In the present invention, there is disclosed a tray (P) of molded material, in particular for fruit, comprising cells (1, 2) for receiving individual fruits is characterized in that the cells (1, 2) are disposed in successive rows of upper cells (1) and of lower cells (2) wherein the upper cells (1) and the lower cells (2) also present a relative disposition in a staggered configuration.
Patent CZ-298693-B6 (CZ)
Title: Unremovable electrical and mechanical connection, contact element and process for producing such connection
Inventor: JAKOB GERT
IPC: H01R12/62
Filed: 2000-12-01
Abstract: The present invention relates to an unremovable electrical and mechanical connection (4) between a contact element (7) having contacts (31) and a counter-contact element (8) having counter-contacts (27) with a flexible section (39) of the contact element (7) in at least a part of the contacts (31). The invention is further characterized in that the contact element (7) has at least one first and second layer (21, 22) that define an intermediate space (23) between them in the zone of the flexible section (39) in which intermediate space (23) the counter-contact element (8) is disposed. The first and the second layer (21, 22) is provided with one contact (31) each on the layer inner sides (40) facing one another. The counter-contact element (8) has at least one counter-contact (27) on each of its upper and lower side (25, 26).
Patent CZ-297488-B6 (CZ)
Title: Folded-seam connection, method of producing thereof and device for making the same
Inventor: BINGGELI RUDOLF
IPC: B21D39/02
Filed: 2000-12-15
Abstract: In the invented folded-seam connection, a flange-like double fold (1) thereof is provided at the first pipe end (X) and is surrounded by a second double fold (2) of the second pipe end (Y), at least in part form fittingly and with an all around continuous metal seal. There is also disclosed a method of producing a double fold at a first pipe end wherein the method is characterized in that - in a first method step a flange-like double fold is produced at a first pipe end, - in a second method step a folding tab with an internal diameter larger than the flange-like double fold is formed on the other pipe end to be joined, - in a third method step the folding tab is pushed over the double fold and after that the projecting part of the folding tab is pressed and clamped against the flange-like double fold in an abutting manner, so that the flange-like double fold is surrounded in a sealed manner. There is further disclosed a device for making the above-described method, wherein the device is characterized in that a displaceable lower roller (21) is constructed in the form of a hollow shaft, a drive shaft (13) carrying a shaping roller (20) fixed in the axial position thereof is provided in the interior of the hollow shaft, the delivery roller (11) is constructed in the form of a hollow shaft, a drive shaft (12) carrying an upper displaceable shaping roller (10) is provided in the interior of the said hollow shaft, the delivery roller (11) and the shaping roller (12) are arranged in slides (38 and 45 respectively) so as to be displaceable in synchronism, and in addition the two rollers (10, 11) are arranged in a slide (37) likewise displaceable against the axially fixed shaping roller (20) and the displaceable shaping roller( 21).
Patent SK-286498-B6 (SK)
Title: Allowing to provide service and charging costs associated with the service
Inventor: BANNELL JOHN LESLEY KINGSFORD
IPC: G07F7/12
Filed: 1999-03-16
Abstract: A system for allowing to provide service and for charging the costs associated with providing the service to a vehicle or to a customer, which system comprises means for providing service to the vehicle, a vehicle recognition system capable of producing characteristic vehicle data, a customer recognition system capable of producing characteristic customer data, a data processing means which is connected to the recognition systems so as to receive the characteristic data, which data processing means includes a storage device including records containing characteristic data of the vehicle and the related customer, a system for comparing the produced characteristic data of the vehicle and the customer with the stored characteristic data,; means for allowing the service to be provided when the produced characteristic data agree to one set of characteristic data of the vehicle and the related customer, and means for charging the costs to an account.
Patent SK-288682-B6 (SK)
Title: Reservoir of dry ice cleaning equipment for dry ice
Inventor: BAKALA LUDOVIT
IPC: B24C7/00
Filed: 2015-08-29
Abstract: Dry ice container for dry ice cleaning equipment includes a dry ice container (1) on the top side closed with a lid (2) and on the lower side provided with an opening (3) for sucking dry ice granulate. The container (1) has a bottom (4) sloping towards the granulate extraction opening (3). A linearly movable member (5) is disposed transversely to the container (1) at the bottom (4). The member (5) is in the form of a trough in which groups of separate openings (5a, 5b, 5c) are formed, to which at least one granulation element (5d) is arranged in the member (5). Each aperture group (5a, 5b, 5c) belongs to one opining(3).
Patent AU-2001257024-B8 (AU)
Title: Control of fruit dehiscence in arabidopsis by indehiscent1 genes
Inventor: YANOFSKY MARTIN F
IPC: C07K14/415
Filed: 2001-04-13
Granted: 2007-05-24
Abstract: The present invention provides methods and compositions that modulate fruit dehiscence in plants.
Patent BR-PI0408457-B8 (BR)
Title: emplastro adesivo contendo agente antiinflamatório não-esteroidal
Inventor: KIYOMI TSURUDA
IPC: A61K31/196
Filed: 2004-03-18
Abstract: "emplastro adesivo contendo agente antinflamatório não-esteroidal". a presente invenção refere-se a emplasto adesivo contendo um agente antiinflamatório não-esteroidal, compreendendo um suporte e uma camada adesiva laminada sobre este suporte, onde a camada adesiva contém um agente antiinflamatório não-esteroidal tendo um grupo carboxila ou seu sal, e polietileno glicol tendo um peso molecular médio de 1000 ou mais.
Patent BR-PI0419032-B8 (BR)
Title: composição farmacêutica de liberação prolongada de hidralazina
Inventor: ALEJANDRO MOHAR BETANCOURT
IPC: A61K9/22
Filed: 2004-09-09
Abstract: composição farmacêutica de liberação prolongada de hidralazina e seu uso como apoio para o tratamento do câncer. a presente invenção se refere a uma forma de liberação prolongada de hidralazina para se utilizar na terapia contra o câncer. esta forma de liberação prolongada de hidralazina permite que se alcance no sangue uma concentração constante do princípio ativo que permite que se apresente o efeito desmetilante da hidralazina sem que apareça sua ação hipotensora, o que permite seu uso na terapia contra o câncer.
Patent BR-PI0520435-B8 (BR)
Title: artigo absorvente com ajuste melhorado
Inventor: ELFSBERG CAMILLA
IPC: A61F13/532
Filed: 2005-07-13
Abstract: artigo absorvente com ajuste melhorado. a presente invenção se refere a um artigo absorvente (10) possuindo porções dianteira (12), de gancho (14) e traseira (16) . o artigo compreende um núcleo absorvente (18) de construção unitária e de densidade uniforme, que é definido por um par de bordas longitudinais opostas (20, 22) e por um par de bordas transversais opostas (24, 26) . o núcleo absorvente (18) tem ao menos uma primeira região (28) e uma segunda (30) região, a espessura média do núcleo absorvente (18) nestas primeira e segunda regiões (28, 30) sendo inferior à espessura média do núcleo absorvente (18) circunvizinho às ditas primeira e segunda regiões (28, 30), ditas primeira e segunda regiões de espessura inferior (28, 30) sendo dispostas simetricamente em relação à linha central longitudinal a do artigo de tal maneira que cada uma das primeira e segunda regiões de espessura inferior (28, 30) se estende até a respectiva borda longitudinal (20, 22) do núcleo absorvente. a distância (as) entre ditas primeira e segunda regiões de espessura inferior (28, 30) no sentido transversal variando ao longo do sentido longitudinal do artigo. uma distância mínima (aí) entre ditas primeira e segunda regiões de espessura inferior (28, 30) no sentido transversal ficando situada ao menos na transição (32) entre a porção de gancho (14) e a porção dianteira (12) . o artigo fornece ajuste bom e seguro e elevado conforto ao usuário.
Patent BR-PI0604782-B8 (BR)
Title: elemento estofado para um leito de paciente com uma placa de fundo e mesa de operação com um leito
Inventor: BERNHARD KATZENSTEIN
IPC: A61G7/002
Filed: 2006-11-10
Abstract: elemento estofado para uma maca de uma mesa de operação. a presente invenção refere-se a um elemento estofado (10) para uma maca de paciente com uma placa de fundo (12), duas partes laterais (14) alongadas feitas de espuma indeformável (22), que ficam dispostas ao longo de duas bordas contrapostas da placa de fundo (12), e abrange uma parte estofada (16), que consiste ao menos parcialmente em espuma macia e assim se adapta entre as partes laterais (14) alongadas de tal maneira que encosta ao menos com seus lados externos (32) ao menos parcialmente na parte lateral (14) respectivamente vizinha, sendo que em uma parte lateral (14) ao menos um segmento (28) saliente está de tal maneira executado e disposto que engata em um recesso (34) correspondente no lado externo (32) da parte estofada (16), quando a parte estofada (16) fica disposta entre as partes laterais (14).
Patent BR-PI0713031-B8 (BR)
Title: composto de di-hidro-piran-2-ona, composição farmacêutica, e uso dos mesmos
Inventor: Alberto Rodríguez Vicente
IPC: A61K31/351
Filed: 2007-06-15
Abstract: composto antitumoral, processo para obtenção deste, composição farmacêutica que o compreende e uso deste. são proporcionados compostos antitumorais obtidos a partir de poríferos, da família raspailiidae, gênero lithoplocamia, espécie lithistoides e derivados dos mesmos.
Patent BR-PI0910541-B8 (BR)
Title: compostos de tetrazol
Inventor: JAMES DENNEN O'NEIL
IPC: A01N43/64
Filed: 2009-04-30
Abstract: composto tetrazol e suas composições farmacêuticas para uso na redução da concentração de ácido úrico no sangue ou aumento da excreção de ácido úrico em um sujeito. a presente invenção refere-se a redução de ácido úrico em indivíduos mamíferos e aumento da excreção de ácido úrico através da administração de um composto da fórmula i. os efeitos da diminuição do ácido úrico dos compostos da invenção são usados para tratar ou prevenir uma variedade de condições incluindo gota, hiperuricemia, níveis elevados de ácido úrico que não encontram níveis costumeiramente justificando um diagnóstico de hiperuricemia, disfunção renal, pedras nos rins, doença cardiovascular, risco para desenvolver doença cardiovascular, síndrome de lise tumoral, comprometimento cognitivo, hipertensão essencial com início precoce, e inflamação induzida por plasmodium falciparum. na fórmula i, x é1 ou 2; y é 0, 1, 2 ou 3; e r1 é selecionado do grupo consistindo em hidrogênio, alquila tendo 1 ou 2 átomos de carbono, hidróxi, alcóxi tendo 1 ou 2 átomos de carbono, flúor, cloro, bromo, e amino. a é fenila, substituída ou não substituída por um, dois ou três grupos selecionados do grupo consistindo em halo, alquila tendo 1 ou 2 átomos de carbono, perfluorometila, alcóxi tendo 1 ou 2 átomos de carbono, e perfluorometóxi; ou cicloalquila tendo 3 a 6 átomos de anel em que a cicloalquila é não-substituída ou um ou dois carbonos de anel são independentemente monossubstituídos por metila ou etila; ou um anel heteroaromático de 5 ou 6 membros tendo 1 ou 2 heteroátomos de anel selecionados de n, s e o e o anel heteroaromático é covalentemente ligado ao restante do composto por um carbono de anel.