baber/WOPTO huggingface dataset:
Patent EA-202192323-A1 (EA)
Title: Рекомбинантный аденоассоциированный вирус для лечения grn-ассоциированной нейродегенерации взрослых
Filed: 2020-02-21
Abstract: Предложен рекомбинантный AAV (rAAV), подходящий для применения при лечении нейродегенерации у взрослых, вызванной гаплонедостаточностью гранулина (GRN), такой как связанная с програнулином (PGRN) лобно-височная деменция (ЛВД). rAAV содержит (a) капсид аденоассоциированного вируса 1 и (b) геном вектора, упакованный в капсид AAV, причем указанный геном вектора содержит инвертированные концевые повторы AAV, кодирующую последовательность для програнулина человека и регуляторные последовательности, которые управляют экспрессией програнулина. Также предложен способ для лечения пациента-человека с PGRN-ЛВД и другой нейродегенерацией у взрослых, вызванной гаплонедостаточностью гранулина (GRN), включающий доставку в центральную нервную систему (ЦНС) рекомбинантного аденоассоциированного вируса (rAAV), имеющего капсид AAV аденоассоциированного вируса 1 (AAV1), при этом указанный rAAV дополнительно содержит геном вектора, упакованный в капсид AAV, при этом указанный геном вектора содержит инвертированные концевые повторы AAV, кодирующую последовательность програнулина человека и регуляторные последовательности, которые направляют экспрессию програнулина.
Patent EA-202192800-A1 (EA)
Title: Способы противоопухолевой терапии
Filed: 2020-04-13
Abstract: Изобретение относится к способам лечения опухоли у нуждающегося в этом субъекта, предусматривающим введение субъекту комбинации эффективной дозы вектора, содержащего ген химерного белка на основе Fas, функционально связанный с промотором, специфическим в отношении эндотелиальных клеток, и эффективной дозы ингибитора контрольной точки иммунного ответа. Согласно некоторым аспектам настоящего раскрытия ингибитор контрольной точки иммунного ответа представляет собой антагонист PD-1 или антагонист PD-L1.
Patent ES-2193803-A1 (ES)
Title: Supporting device for vertical rising doors.
Inventor: MIR DARNACULLETA ANGEL
IPC: E06B9/84
Filed: 2000-06-29
Abstract: This device is applicable to doors fitted with a shaft (2) driven by a motor (3) designed to cause vertical movement of the door (1) by a rotary motion. The said device includes: a fixed body (5) through which passes the shaft (2), a brake (6) mounted so that it can move longitudinally on the portion of the shaft (2) housed in the body (5), retractable stops (8) mounted on the sides of the body (5), means for pushing the stops (8) to their operating position, means for holding the stops (8) in the inoperative position and means for actuating the means for holding the stops (8), causing their release and lateral movement of the brake (6) against the body (5) when the shaft (2) is rotating at a high speed.
Patent ES-2179742-A1 (ES)
Title: Fabrication of sacrificial shuttering for lightweight concrete e.g. walls consists of vibration of a uniform expanded polystyrene beads, cement, water and sand mixture after moulding
Inventor: PRINCIPE CENTENO ROBERTO
IPC: E04G11/40
Filed: 2000-08-09
Abstract: The fabrication of sacrificial shuttering of lightweight e.g. walls comprises pouring of a uniform mixture of expanded polystyrene beads, cement, water and sand, for pressing or e.g. vibration after setting in the mould. The product can have specific shape, profile, physico-chemical and mechanical properties as desired.
Patent ES-2199001-A1 (ES)
Title: Pipe work support comprises base and fixing parts, base with rigid section and elastomer block with several parallel hollows and fastening part with rigid section with elastomer block
Inventor: BLANCHET LUCIEN
IPC: F16L3/223
Filed: 2000-09-07
Abstract: Pipe work support comprises base part (1) and fixing part (2). Base has rigid section (4) and elastomer block (5) comprising face fixed to rigid section and opposite face with parallel hollows (8',8). Fastening part comprises rigid section (10) and elastomer block (11). The two parts are passed through by holes (3) for assembly screws and have stops (9) which limit compression of elastomer blocks during tightening of screws.
Patent ES-2220190-A1 (ES)
Title: Throat-slitting device and uses thereof
Inventor: CASANELLAS MILA JOSEP
IPC: A22B5/04
Filed: 2002-08-28
Abstract: Sticking trough and corresponding uses. Sticking trough suitable for bleeding an animal suspended vertically head down, which comprises a blood collection recipient (1) for collecting blood from an animal transported by a carry-forward device and means of transport which support the animal's forefeet. The means of transport move at the same speed as the carry-forward device. The sticking trough preferably comprises a railing (23) parallel to the blood collection recipient (1), and the means of transport have compartments (15) each suitable for receiving a foot of the animal. Preferably the sticking trough is used for collection of blood from porcine, bovine, ovine and/or equine livestock and which is suitable for: human consumption, animal consumption, preparation of pharmaceutical products, preparation of veterinary products, medical purposes, and/or biotechnological purposes.
Patent ES-2232246-A1 (ES)
Title: Polygonal shaped oscillating brush tool, has brush inserted into oblique hole, mechanical transmission input shaft attached with rotating sleeve, and double universal joint connected with rear end of housing support
Inventor: MADAULA LATORRE JOSE
IPC: B23B41/04
Filed: 2002-09-26
Abstract: The tool has a housing support (1) provided with a rotating sleeve (3) that is mounted on a shaft (31). The rotating sleeve is provided with an oblique hole (33). An axis (34) of the rotating sleeve is equipped with an axis of a drawing unit. A cap is connected at an anterior end (91) of a brush (9). The brush is inserted on the oblique hole. A mechanical transmission input shaft (4) is attached with the rotating sleeve. A double universal joint (10) is connected with a rear end (92) of the housing support.
Patent ES-2216692-A1 (ES)
Title: Expanding dental implant for inserting into bone, has two pieces joined together by thread, cylindrical stem provided with threaded head that is inserted into threaded hole, and outer part connected with rod
Inventor: ARRIZABALAGA MORENO FEDERICO
IPC: A61C8/00
Filed: 2002-12-18
Abstract: The implant has two pieces joined together by a thread, and a cylindrical stem (3) provided with a threaded head (4) that is inserted into a threaded hole (5). An outer part (2) is connected with a rod, where the outer part includes a screw (8). A lower end of the screw extends toward a lower end to provide better cutting introduction into a host bone. A hole (15) is formed in a bottom of the outer part for introduction of a mechanical element to secure bone fixation.
Patent ES-2264842-A1 (ES)
Title: Sealing bellows, transmission joint equipped with same and method for fixing same
Inventor: NEVIANI CLAUDE
IPC: F16C1/26
Filed: 2001-12-13
Abstract: The invention concerns a bellows (2) comprising a bellows body (10) provided at each end with a lug (12) designed to provide sealed contact with the periphery of a shaft or an element (7) of the joint integral with a shaft. Each lug (12) comprises a radially outer shoulder (16) providing transition between the lug (12) and the bellows body (10), and a support surface (20) designed to receive a member (22) such as a ring or a clamp, for tightly fixing the lug against the shaft or the associated element. The support surface (20) extends from the shoulder (16) and extends further up to the end of the lug (12) without any increase in diameter. The shoulder (16) is adapted to form a longitudinal positioning stop when the fixing member (22) is mounted. The invention is applicable to bellows with lugs fixed by swage-crimping of a closed ring.
Patent ES-2265730-A1 (ES)
Title: Toy ball integrated table apparatus, has main body provided with two handles for controlling and managing rods, which are arranged in moving carts, where main body is made one of wood, acrylic fiber or molded plastic material
Inventor: ESTEBAN PEDRO LUIZ
IPC: A63F7/02
Filed: 2004-09-17
Abstract: The apparatus has a main body provided with two handles for controlling and managing rods, which are arranged in moving carts, where the main body is made one of wood, acrylic fiber or molded plastic material. An inner side of the main body is provided a ramp system such that running game balls reach a finish line. A lift is driven by a drive pulley and fixed with side flanks of the main body. The lift is protected by an outer structure. A fiber glass body is fastened on an outer side of the main body.
Patent ES-2226590-A1 (ES)
Title: Mechanical stimulation device for stimulating perineal area, has body comprising top portion, bottom portion, interior wall and suspension units, where end of suspension units is connected to pendulum
Inventor: POLO EGUIA MARIA OLGA
IPC: A61H19/00
Filed: 2004-11-08
Abstract: The device has a body (2) comprising a top portion (21), a bottom portion (22), an interior wall (13) and suspension units (5). An end (51) of the suspension units connects the interior wall with the top portion. Another end of the suspension units is connected to a pendulum (4). The pendulum is attached with the interior wall of the body.
Patent ES-2261079-A1 (ES)
Title: Transparency and concealment technique for objects, structures or spaces, involves placing transparency and concealment unit between screen and camera to reproduce image with transparency and concealment effects on screen
Inventor: DE LA PAZ MARTINEZ MANUEL
IPC: G02B27/01
Filed: 2005-04-18
Abstract: The method involves using cameras or an image capturing system arranged at the later portion of a transparency or concealment unit, and screens or an image reproducing system arranged before the transparency or concealment unit. The screens reproduce the images, captured by the cameras, with transparency and concealment effects due to the transparency and concealment unit placed between the screens and cameras.
Patent ES-2294897-A1 (ES)
Title: Woven strip for use as label, is obtained from woven tape, which is cut cross-sectional, where tissue of weave on double slide to determine long face coarse of warping thread is provided and compare length of coarse of threads
Inventor: MASO MARCET JOSE MARIA
IPC: D03D15/567
Filed: 2005-10-14
Abstract: The woven strip is obtained from a woven tape, which is cut cross-sectional, where tissue of the weave on the double slide to determine a long face coarse of warping thread is provided and compare the length of the coarse of threads in opposite of the weave. The thread of warping of a hygroscopic material and has submissive weave, where a stage of moisture, natural or forced during texture or in an immediately later period is provided. Another drying stage is provided that produces shrinking of the long coarse of warping threads.
Patent ES-2299382-A1 (ES)
Title: Lighting management system for hospitals, has base structure of lighting system, which is based on digital addressable lighting interface protocol and sensor is provided that monitors existing natural light
Inventor: PALOTTA ROMERO ROBERTO OMAR
IPC: H05B37/02
Filed: 2006-11-07
Abstract: The system has a base structure of a lighting system, which is based on a digital addressable lighting interface (DALI) protocol. A DALI control unit and a series of connecting electronic equipment are provided that associates different lighting lamps. A sensor is provided that monitors the existing natural light. The control unit is associated through a node in the physical circuit in an automatic programmable interface to enter a signal controlled through the software programmable control unit to conduct a management based on statistical data and extreme variables.
Patent RS-20200730-A1 (RS)
Title: System which uses sea waves to accumulate water at a certain height for electricity generation, optionally desalination
Inventor: GUTOVIĆ ZORAN
IPC: F03B13/12
Filed: 2020-06-18
Abstract: A system that uses sea waves to accumulate water at a certain height for its use to obtain electricity and, if necessary, desalination consists of two or three functionally connected parts whose basic elements are: working float (1) connected to the inner cylinder (3) ) extending along the longitudinal axis of the float comprising a compression cylinder (2), with a stabilizer (30), along which it can, under the influence of sea waves, move up and down by pulling a sealing piston (4) to which it is connected by a rigid connection (5) so that its movement creates conditions, pressure and underpressure, to open one-way valves on the compression cylinder (2), inlet (6) or (7) or both and outlet valve (8) located at the inlet to the buoyancy pipe (9) which can go directly to the storage tank (10) from where the pipe (26) goes vertically downwards so that with the system (29) the controlled amount of water, through it, reaches the turbine (27) connected to the generator (28) by free fall. In order to include desalination in the whole process, the buoyancy pipe (9) bifurcates at a given height into a pipe (12) that goes into a closed evaporator tank (11) whose filling, up to a certain level, closes the tank and activates the pipe (13) which is at a slightly higher height and leads to a flow cooler (24) which comprises a tube (21) into which steam enters at the top of the evaporator (11), while the flow cooler (24) pours into the storage tank (10) at position (25), and condensed, desalinated water comes out of the pipe (23). In order to reduce the influence of the progressive movement of the wave on the working float (1), it can be fitted with arms (32), with floats (35) which ring-shaped or semi-ring-shaped (33) encloses columns (34) firmly buried in the bottom, as well as (or) to surround this part of the system with a barrier in the form of half-walls of the cylinder (37) which are offset from each other and placed so that their ends overlap considerably.
Patent SG-87894-A1 (SG)
Title: Electrolysis process
Inventor: DR FRITZ GESTERMANN
IPC: C25B1/34
Filed: 2000-05-24
Abstract: The invention relates to a process for the electrolysis of sodium chloride-containing brine with parallel operation of amalgam electrolysis units (5) and membrane electrolysis units (4) with a common brine circuit using a mercury-resistant oxygen consumable cathode in the membrane electrolysis unit (4).
Patent SG-125187-A1 (SG)
Title: Analog electronic clock having reset current conductive structure
Inventor: EBI AKIRA
Filed: 2006-02-03
Abstract: To provide a reset current conductive path between a rest lever (3) and an overhang of a printed circuit board (4) without using a conductive part such as a metal pin and without bending a distal end portion of the reset lever (3). An overhang pattern(4a) accommodated in an embracing recessed portion (l d), which is formed in a plate (1), is bent to a height of the reset lever (3) and a distal end portion of the overhang pattern (4a) reaches a recessed portion which is dug downwardly from a rest lever planar moving surface (1 a). The bent state of the overhang pattern (4a) is held by arm portions of the embracing recessed portion (1 d). Accordingly when a winding stem (8) is pulled by one stage, the reset lever (3) performs the planar movement in the given direction and a distal end portion of the reset lever (3) is brought into contact with the overhang portion (4a). Accordingly it is possible to form a reset current conductive path which transmits a potential applied to the reset lever when the gear train is stopped to an IC which is mounted on the printed circuit board (4).
Patent TR-200903671-A1 (TR)
Title: İçten yanmalı motorlar için döner tip valf sistemi.
Inventor: OEZCAN ERG
IPC: F01L7/04
Filed: 2009-05-12
Abstract: İçten yanmalı motorların emme ve egzoz fazlarını yapmak üzere tasarlanmış, kam tahrik mekanizması ile silindir dış yüzeyinde dönerek çalışan valf sistemidir. Tasarlanan valf mekanizması vasıtasıyla; motor emme açısına geldiğinde silindir yüzeyindeki kanalların valf üst yüzeyine bağlanan kanallar ile üst üste gelmesiyle silindir içerisine hava-yakıt emişinin yapılmasına, valf hava kanalları arasındaki düz yüzeyin silindir üzerindeki kanala denk gelmesi sonucu temas eden iki yüzey arası yağ filmi tabakası oluşturularak sıkıştırma ve yanma basınçlarının korunmasına ve motor egzoz açısına geldiğinde ise silindir üzerindeki kanalların valfin alt yüzeyine bağlanan kanalları ile üst üste gelmesiyle yanmış gazların dışarı çıkması sağlanmaktadır. Bu sistemin uygulanması ile içten yanmalı motorlarda karşılıklı çalışan iki piston yerleştirilerek üst ölü noktadan kaçırılmış bir noktada sıkıştırmanın oluşturulması ile daha yüksek torkun alınacağı krank açılarında yanma başlangıcının oluşması sağlanmaktadır.
Patent TR-201104769-A1 (TR)
Title: Akıllı emanet dolabı yöntemi ve otomasyonu.
Inventor: KALKAN HABIL
Filed: 2011-05-16
Abstract: Akıllı emanet dolabı yöntemi ve otomasyonu, kullanıcıların bir bedel ödeyerek ve kendilerine ait bir veri girerek eşyalarını teslim edip, sonrasında aynı bilgiyi girerek eşyalarını teslim alma fonksiyonuna sahiptir. Sistem, üzerinde parmak izi giriş paneli (1), şifre giriş paneli ve göstergesi (2), para atma haznesi (3), yüz tanıma için kamera (4), eşya teslim bölmesi (5), hareketli eşya istif kasaları (8) ve eşya taşıma platformu (7) ve elektronik üniteden oluşmaktadır. Para atma haznesine (3) para atılarak başlatılan işlemde öncelikle eşya teslim dolabı açılır (5) ve eşya burada bulunan eşya taşıma platformu (7) üzerine yerieştirilir. Sonrasında veri giriş tercihi yapılarak parmak izi (1), yüz görüntüsü (4) veya şifre giriş (2) panellerinden biri kullanılarak veri girilir. Veri girişi tamamlanınca hareketli platform (7) emaneti boş olan bir kasaya yerieştirir. Kullanıcı eşyasını teslim almaya geldiğinde ise teslim ederken girdiği yeriyi tekrar girer ve otomasyon sistemi ilgili kutuyu (6) sistem içerisinde bulur. Kutuyu taşıyan kasaya erişim için bu kasanın bir tarafı boş olacak şekilde bloklar hareket ettirilir ve platform ilgili kasaya giderek eşyayı alıp dikey koridordan (10) ilerleyerek sabit olan yatay koridora (9) iletir. Bu koridor boyunca ilerleyen kutu emanet teslim bölmesine gelir ve kapak (5) açılarak kullanıcıya teslim edilir.
Patent TR-201500002-A1 (TR)
Title: Dokunmatik kumanda paneli.
Inventor: NURETTİN KÜÇÜKÇALI
IPC: F24H9/20
Filed: 2015-01-02
Abstract: Bu buluş; bir veya birden fazla gaz yakıtlı kazan ve ısıtma devrelerinin kontrolünü sağlayan, ısıtma sistemi kontrolü için kullanılan dokunmatik kumanda paneli ile ilgilidir.
Patent TR-201620204-A1 (TR)
Title: Aksi̇yon kameralar i̇çi̇n hari̇ci̇ bi̇r bulut üzeri̇nde yedekleme ve kontrol ci̇hazi
Inventor: ANIL BERKE KAVRAAL
IPC: H04N5/225
Filed: 2016-12-30
Abstract: Buluş hücresel kablosuz haberleşme (GSM) şebekesi vasıtasıyla aksiyon kameralara (10) haricen takılarak görüntü ve ses gibi medya içeriğinin anlık ve sürekli olarak yedeklenmesi (backup) ve uzaktan kontrolü için bir yedekleme cihazıdır (11). Buluş konusu cihaz SIM kart bağlı olan ve BTS (20), SGSN (21) ve GGSN (22) gibi elemanlar üzerinden bir mobil haberleşme şebekesine bağlı olan bahsedilen yedekleme kiti (11); bağlandığı cihaza veri yolu (data bus) aracılığı ile bağlanarak cihazdan veriyi bir tampon (12) alanına alıp bir GSM şebekesi üzerinden TCP protokolü ile yedekleyen buluttaki bir yedekleme sunucusu (30), yapılan yedekleme (backup) şebeke üzerinden internete (34) erişerek verinin beslendiği kullanıcının belirlediği bir bulut saklama sistemi, ayrıca verinin eksiksiz ve hatasız transfer edildiğini kontrol etmek için verinin sağlamasının kayıt altına alındığı bir sağlama veritabanı (33) içermektedir.
Patent AR-022516-A1 (AR)
Title: Estructura de cano y metodo de fabricacion
IPC: B29C48/18
Filed: 2000-02-04
Abstract: Una seccion de cano formado a partir de material polimérico que tiene un grosor substancialmente constante en todas sus partes, y el borde terminal de laconexion hembra que tiene una estructura de refuerzo que otorga rigidez al extremo de laconexion hembra e impide la deformacion; la seccion de canopreferentemente tiene un extremo acampanado y la estructura de refuerzo es preferentemente un canal semicircular formado al extremo de la seccion de cano porun mandril, después de laextrusion inicia l de la seccion de cano; junto con un método y un aparato para formar la seccion de cano, un conjunto de canos queincluye tal seccion de cano y un método para formar el conjunto de canos.
Patent AR-023513-A1 (AR)
Title: Articulo absorbente que tiene un revestimiento contacto-cuerpo con locion hidrofilica.
IPC: A61L15/26
Filed: 2000-04-14
Abstract: Un artículo absorbente que tiene un revestimiento contacto cuerpo que incluye una formula de locion hidrofílica sobre la superficie contacto cuerpoexterior del mismo. La formula de locion hidrofílica comprende de alrededor de 10 a alrededor de 90por ciento en peso de un solvente hidrofílico, de alrededorde 5 a alrededor de 90 por ciento en peso de un polietilenglicol de peso molecular superior, y de alrededor de 0 a alrededor de 60 por ciento en peso de unalcohol graso. La formula de locionhid rofílica tiene un efecto adverso reducido sobre las propiedades de absorcion de líquido y absorbentes del revestimientoy del cuerpo absorbente cuando se compara con las formulas de locion lipofílicas o hidrofobicas convencionales. La formula delocio n hidrofílica actua como unlubricante para reducir la abrasion de la piel causada por el revestimiento y también es transferida a la piel para proporcionar una salud de piel mejorada.
Patent AR-033942-A1 (AR)
Title: Compuestos de monofluoroalquilo aplicables en la potenciacion de los compuestos intermediarios utilizables en la sintesis de dichos compuestos de monofluoralquilo; composiciones farmaceuticas formuladas con dichos compuestos potenciadores y metodos para la potenciacion de las funciones de dichos rec
IPC: C07D333/20
Filed: 2000-04-27
Abstract: Se describen y reivindican compuestos monofluoralquilo útiles para la potenciación de la función de los receptores glutamato en mamíferos, y por lo tanto, útiles para el tratamiento de una amplia diversidad de afecciones, como trastornos psiquiátricos y neurológicos. Dichos compuestos responden a la fórmula (1), en la que: A representa SO2, CO2 ó CONH; Ra representa alquilo C1-6, alquenilo C2-6, -alquil C1-4-cicloalquilo C3-8, ó -alquil C1-4-aromático; Rb representa H, alquilo C1-6, alquenilo C2-6, -alquil C1-6-cicloalquilo C3-8, ó -alquil C1-6-aromático; ó Ra y Rb, junto con los átomos de carbono a los que están unidos, forman un anillo carbocíclico C3-8 saturado, un anillo carbocíclico C3-8 saturado, que contiene un heteroátomo seleccionado entre el grupo consistente en azufre y oxígeno, o un anillo carbocíclico C5-8 que contiene un doble enlace; R1 representa un grupo aromático sustituido o no sustituido, un grupo heteroaromático sustituido o no sustituido, o un grupo cicloalquilo C5-8 sustituido o no sustituido; R2 representa alquilo C1-6, cicloalquilo C3-6, fluoralquilo C1-6, cloroalquilo C1-6, alquenilo C2-6, alcoxi C1-4-alquilo C1-4, fenilo no sustituido o sustituido, halógeno, alquilo C1-4 ó alcoxi C1-4, o cuando A representa SO2, un grupo de fórmula R3R4N, en la que R3 y R4 representan, cada uno independientemente, alquilo C1-4, ó junto con el átomo de nitrógeno al que están unidos, forman un grupo azetidinilo, pirrolidinilo, piperidinilo, morfolino, piperazinilo, hexahidroazepinilo u octahidroazocinilo, o sales farmacéuticamente aceptables del mismo. También se reivindican los objetos restantes, mencionados en el título.