baber/WOPTO huggingface dataset:
Patent PE-21191-A1 (PE)
Title: Dispositivo de filtro
Inventor: TUCKER MARTIN ROBILLIARD
IPC: B01D25/00
Filed: 1989-09-28
Abstract: CARACTERIZADO POR COMPRENDER BACTERIAS GRAM-NEGATIVAS PRODUCTORAS DE EXO-POLISACARIDO SOBRE SOPORTE DE MATERIAL PERMEABLE AL AGUA QUE NO SEA TOXICO PARA LOS MICRO ORGANISMOS Y LOS SERES HUMANOS, RESISTENTE A TEMPERATURAS COMPRENDIDAS ENTRE -15°C Y 65°C Y QUE NO SEA FACILMENTE BIODEGRADABLE. EL PRESENTE FILTRO ES PARA EL TRATAMIENTO DE AGUAS, A FIN DE HACERLAS POTABLES
Patent PL-237362-A1 (PL)
Title: Thermal shield securing device
IPC: F02B77/02
Filed: 1982-07-08
Abstract: An attachment for a heat shield is intended to protect the face of the cylinder head comprising one of the walls of the combustion chamber of the cylinder of an internal combustion engine in which the transfer of gases is controlled by valves having seats inserted into the cylinder head. The inserted seats of the valves are provided with an annular rim which, when the seat is fitted into a bore in the cylinder head, presses against the wall of the cylinder head the heat shield. Application is to insulating the inner walls of a heat engine cylinder head or to creating hot points in the combustion chamber of the cylinder head.
Patent PL-270559-A1 (PL)
Title: Piston internal combustion engine with filling degree increasing due to resonance vibrations of fresh gas
IPC: F02B27/00
Filed: 1988-02-10
Abstract: A reciprocating piston-type internal combustion engine includes an intake gas conduit assembly in which intake gas resonance oscillations are generated for increasing the charging efficiency of the cylinders. The intake gas conduit assembly has a feed resonance system including a feed resonator vessel connected with the intake ports of a group of cylinders whose suction strokes do not significantly overlap and a feed resonance pipe communicating with the feed resonator vessel. The intake gas conduit assembly further has an auxiliary resonance system including a closed auxiliary resonator vessel and an auxiliary resonance pipe opening into the auxiliary resonator vessel, an intermediate resonator vessel coupled with the auxiliary resonance pipe and the feed resonance pipe and an intake gas inlet pipe coupled with the intermediate resonator vessel. The feed resonance system and the auxiliary resonance system are tuned to one another by a dimensional selection such that at a predetermined first resonance rpm of the engine the intake gas oscillations generated in the feed resonance pipe and the auxiliary resonance pipe by intermittent suction strokes of the cylinders forming the group are in phase effecting an increase in the charging efficiency and the intermediate resonator vessel is dimensioned such that at a predetermined second resonance rpm of the engine in an operational rpm range the oscillations in the feed resonance pipe and the auxiliary resonance pipe are of opposite phase, effecting an increase in the charging efficiency.
Patent PL-289217-A1 (PL)
Title: Method of obtaining a novel ethylene/pentene-1 copolimer and ethylene/pantene-1 copolimer mixture
Inventor: KIOKA MAMORU
IPC: C08F210/14
Filed: 1991-02-27
Abstract: The present invention relates to a novel ethylene/pentene-1 copolymer whose molded film has a good balance between impact resistance and tear properties and high transparency, also is prominently reduced in a variation of the transparency even after subjected to a heat treatment, and further shows high blocking resistance, provided that the copolymer fulfills specific requisites. The invention also relates to a process for the preparation of the above-mentioned ethylene/pentene-1 copolymer and a formulation of the ethylene/pentene-1 copolymer composition using a stabilizer. According to the invention, there can be obtained an ethylene/pentene-1 copolymer composition which is excellent in heat stability in the molding stage, long-term heat stability and weatherability.
Patent PL-309168-A1 (PL)
Title: Phenyl-substituted perfluoroalkyl group containing guanidides of alkylene carboxylic acids, method of obtaining them and therapeutic agent containing such compounds
Inventor: SCHWARK JAN-ROBERT
IPC: C07C279/22
Filed: 1995-06-19
Abstract: Perfluoroalkyl-substd. phenylalkenoyl-guanidine derivs. of formula (I) and their salts are new. Ra and Rb=H, halogen, CN, OH, OR6, 1-8C alkyl, Or(CH2)aRf, 3-8C cycloalkyl or NR7R8; r=0 or 1; a=0-4; Rf=1-8C perfluoroalkyl; R6=1-8C alkyl, 1-4C perfluoroalkyl, 3-8C alkenyl, 3-8C cycloalkyl, or phenyl or benzyl ring-substd. by 0-3 of F, Cl, CF3, Me, OMe and NR9R10; R9 and R10=H, 1-4C alkyl or 1-4C perfluoroalkyl; R7 and R8=gps. as defined for R6, or R7+R8=4 or 5 CH2 gps., one of which is opt. replaced by O, S, NH, NMe or NCH2Ph; x and y=0-2; Rc and Rd=H, halogen, CN, OR6, 1-8C alkyl, Or(CH2)aRf or 3-8C cycloalkyl; R1-R5=H, 1-8C alkyl, Or(CH2)aRf, 3-8C cycloalkyl, halogen or CN; provided that at least one of Ra, Rb, Rc, Rd, R1, R2, R4 and R5 is Or(CH2)aRf, and that R3 is not Or(CH2)aRf.
Patent PL-309662-A1 (PL)
Title: Method of obtaining highly reactive urea-modified phenolic resins as a binder for internal layers of chips in production of chipboards
Inventor: BUSCHFELD ADOLF
IPC: C08G14/08
Filed: 1993-12-20
Abstract: PCT No. PCT/DE93/01236 Sec. 371 Date Jun. 29, 1995 Sec. 102(e) Date Jun. 29, 1995 PCT Filed Dec. 20, 1993 PCT Pub. No. WO94/15982 PCT Pub. Date Jul. 21, 1994Urea-modified, highly reactive phenolic resins useful as center-layer bonding agents in the manufacture of particleboard are provided by condensing phenol and formaldehyde until shortly before gelation takes place such that, after addition of urea, relatively low-alkaline, urea-modified phenolic resins are obtained which my optionally be stored and to which, shortly before processing them into glues for center-layer particles, alkali is added in sufficient quantities to ensure rapid cross-linking of the phenolic resin.
Patent PL-310229-A1 (PL)
Title: Method of and apparatus for protecting working area of emptying machines
Inventor: ZHANG HAIPING
IPC: G01V8/12
Filed: 1995-08-30
Abstract: The lateral regions adjacent to the emptying device or devices are protected by barriers (6,7). At least during one time period, i.e. the monitoring phase, of the emptying process, the introduction region between the barriers is protected by a light barrier (18,8,9,14). If the light barrier is interrupted, the emptying process is prevented or interrupted. The light barrier is activated when the emptying device has reached a defined lifting height or when the waste container is locked onto the emptying device.
Patent PL-312714-A1 (PL)
Title: Therapeutic agent
Inventor: DAUNTER BRIAN
IPC: C07D209/46
Filed: 1994-06-24
Abstract: A method for the treatment of an inflammatory complaint including the step of administration of a compound of general formulae (I to XII) described herein in figure or mixtures thereof to a subject suffering from said inflammatory complaint. There is also included a therapeutic agent for relief of inflammatory complaints which includes a compound of general formulae (I to XII) as described in figure or mixtures thereof in combination with an appropriate filler which is preferably dicalcium phosphate. The invention also includes within its scope plant extracts which may contain one or more of the above-mentioned compounds and in particular plant extracts of the genus Umbelliferae, celery (Apium graveolens), parsley (Petroselimun hortense) and dill (Anethum graveolens). It is believed that compounds of the above-mentioned formulae and in particular butylphthalide, sedanenolide and sedanolide (in both cis and trans forms otherwise known as essential oils which are mainly derived from plants) mimic the physiological response of essential fatty acids and also their prostaglandin analogues.
Patent PL-316844-A1 (PL)
Title: Method of and apparatus for baking cakes
Inventor: ROECKER HANS DIPL ING
IPC: A47J37/01
Filed: 1994-12-05
Abstract: PCT No. PCT/EP94/04042 Sec. 371 Date Jun. 5, 1996 Sec. 102(e) Date Jun. 5, 1996 PCT Filed Dec. 5, 1994 PCT Pub. No. WO95/15693 PCT Pub. Date Jun. 15, 1995A process is disclosed for baking cakes in which a baking frame is placed on the oven grating. The space delimited by the baking frame and the oven grating is filled with cake dough and the cake is baked therein.
Patent PL-335582-A1 (PL)
Title: Tyre incorporating an electrically oriented composite
Inventor: KRISHNAN RAM MUTTHY
IPC: B60C19/08
Filed: 1998-01-26
Abstract: A rubber tire is provided which contains an electrically oriented composite within a rubber composition component of the tire, wherein said composite is composed of at least two electrically conductive metal elements in close proximity to each other and an electrically conductive rubber composition which is in contact with and electrically connects said metal elements together. The invention also contemplates an electrically resistive rubber composition within said tire rubber component which is juxtapositioned to at least a portion of said electrically conductive rubber composition and to at least a portion of at least one of said electrically conductive metal elements.
Patent PL-336522-A1 (PL)
Title: Window/door for a building
Inventor: STRUTH FRITZ
IPC: E06B5/11
Filed: 1998-05-07
Abstract: The invention relates to a window/door for a building having a burglar alarm (11, 111) fitted between the window frame/door frame (1) and the window casement/door leaf (2) which emits an alarm signal. The invention is characterized in that the burglar alarm has a detection zone along the beams of frame, by means of which the penetration of a break-in tool (10) into the first partition line (9) between the window/door frame and the window casement/door leaf is turned into an alarm signal.
Patent PL-338925-A1 (PL)
Title: Improved shuttering for errection of building walls
IPC: E04B2/86
Filed: 1998-08-22
Abstract: A formwork for building bearing walls comprises a plurality of pairs of facing panels (PE, PI) connected together so as to form an inside space between them, said pairs of facing panels being arranged in superimposed rows, the panels of each pair being connected to each others by braces (6) of adjustable length with both the braces (6) and the panels (PE, PI) being left in the wall formed when a cementitious material poured in said inside space has solidified. The so formed walls are provided with bearing partition members and ventilating duct, and are strongly insulated and already finished (FIG. 6).
Patent PL-345809-A1 (PL)
Title: Amide derivatives which are useful as cytokine inhibitors
Inventor: BROWN DEARG SUTHERLAND
IPC: C07D295/135
Filed: 1999-07-29
Abstract: The invention concerns amide derivatives of the Formula (I)wherein R<3 >is (1-6C)alkyl or halogeno; Q is aryl or heteroaryl which optionally bears 1, 2, 3 or 4 substituents such as hydroxy, halogeno, trifluoromethyl, cyano, (1-6C)alkyl, (1-6C)alkoxy, halogeno(1-6C)alkyl, hydroxy-(1-6C)alkyl, di-[(1-6C)alklyl]amino-(1-6C)alkyl, hydroxy-(2-6C)alkoxy, (1-6)alkoxy-(2-6C)alkoxy, di-[(1-6C)alkyl]amino-(2-6C)alkoxy, amino-2(2-6C)alkylamino, N-(1-6C)alkyl-(1-6C)alkylamino-(2-6C)alkylamino, aryl, aryl-(1-6C)alkoxy, heteroaryl, heteroaryl-(1-6C)alkoxy, heterocyclyl, heterocyclyl-(1-6C)alkyl, heterocyclyloxy and heterocyclyl-(1-6C)alkoxy; p is 0-2 and R<2 >is a substituent such as hydroxy and halogeno; q is 0-4; and R<4 >includes optionally substituted aryl, cycloalkyl, heteroaryl and heterocyclyl; or pharmaceutically-acceptable salts or in-vivo-cleavable esters thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines.
Patent PL-353198-A1 (PL)
Title: Use of docetaxel for treating hepatocellular carcinoma
Inventor: CHI CHIN-WEN
IPC: A61K31/00
Filed: 2000-08-29
Abstract: The present invention is based on the finding that docetaxel is significantly more active against hepatocellular carcinoma cells than paclitaxel at concentrations of up to 1 muM. It accordingly provides the use of docetaxel, or a hydrate thereof, in the manufacture of a medicament for use in the treatment of hepatocellular carcinoma.
Patent PL-353999-A1 (PL)
Title: Compositions comprising organosiloxane resins for delivering oral care substances
Inventor: YUE JIANG
IPC: A61P1/02
Filed: 2000-06-09
Abstract: Disclosed is a composition for delivering an oral care substance to the oral cavity, comprising: (a) an organosiloxane resin; (b) a volatile carrier capable of solubilizing the organosiloxane resin; (c) a rheology modifier; and (d) at least one oral care substance. The present invention is also directed to such compositions comprising: (a) an organosiloxane resin; (b) a fluid diorganopolysiloxane polymer; (c) a volatile carrier capable of solubilizing the organosiloxane resin and the fluid diorganopolysiloxane polymer; (d) a rheology modifier; and (e) at least one oral care substance. Further disclosed is a method of using these compositions.
Patent PL-358683-A1 (PL)
Title: Dyeing composition containing an oxidable base of diaminopyrazole, a cationic oxidable base and a coupling agent
Inventor: KRAVTCHENKO SYLVAIN
IPC: A61K8/66
Filed: 2003-02-11
Abstract: A dyeing composition comprises:  (a) at least one 1-alkoxyalkyl-4,5-diamino-pyrazole oxidation base (I); (b) at least one monobenzenoid, dibenzenoid or heterocyclic oxidation base (II) containing aliphatic cationic group(s) (optionally carrying an (un)saturated ring), bonded to at least one ring directly or via amine function(s) carried by the ring; and (c) at least one coupler. A new dyeing composition comprises: (a) at least one oxidation base selected from diaminopyrazoles of formula (I) and their acid addition salts; (b) at least one oxidation base (II) selected from monobenzenoid, dibenzenoid or heterocyclic compounds (optionally as addition salts) containing at least one cationic group Z, bonded to at least one benzene or heterocyclic ring directly or via at least one amine function carried by the ring; and (c) at least one coupler.  R1  =  1-6C alkyl substituted by one or more 1-4C alkoxy groups;  Z  =  cationic group comprising an aliphatic chain, optionally carrying a saturated or unsaturated ring.  Independent claims are also included for the following: (1) an oxidation dyeing method for keratin fibers, involving applying the composition to the fibers and developing the color using an oxidizing agent; and (2) a multi-compartment kit, including one compartment containing the composition and a second compartment containing an oxidizing composition.
Patent PL-364874-A1 (PL)
Title: Control of arthropods in animals
Inventor: HUBER SCOT KEVIN
IPC: A01N47/02
Filed: 2000-12-01
Abstract: A method of controlling parasites in or on an animal comprising administering to the animal a parasiticidally effective, substantially non-emetic 1-arylpyrazole.
Patent PL-366294-A1 (PL)
Title: Holding device
Inventor: SCHULZ RAINER
IPC: F16M13/00
Filed: 2001-08-30
Abstract: The invention relates to an improved holding device for receiving pole-shaped objects, especially trees, christmas trees for example. The inventive device has a plurality of holding elements ( 4-4 c ; 104-104 c), each having a swivel axis ( 7-7 c ; 114-114 c) associated thereto. The holding elements and swivel axes can be moved towards and away from the axis of symmetry and/or central axis ( 115 ), and the holding elements ( 4-4 c ; 104-104 c) and the swivel axes ( 7-7 c ; 114-114 c) associated thereto can be moved by a clamping device ( 2; 102 ), against the force of a spring device ( 10; 13 ).
Patent PL-367464-A1 (PL)
Title: Pharmaceutical composition comprising lumiracoxib
Inventor: KARNACHI ANEES ABDULQUADAR
IPC: A61K47/38
Filed: 2002-08-30
Abstract: Disclosed herein are tablets and methods of treatment comprising the administration of such tablets. The tablets are immediate release tablets that comprise about 400 mg of 5-methyl-2-(2'-chloro-6'-fluoroanilino)phenylacetic acid or a pharmaceutically acceptable salt thereof, where the 5-methyl-2-(2'-chloro-6'-fluoroanilino)phenylacetic acid or a pharmaceutically acceptable salt thereof comprises between 60 and 70% by weight of the tablet. The methods involve the administration of the tablets of the invention to individuals in need of administration of such tablets.
Patent PL-374041-A1 (PL)
Title: Pharmaceutical composition having a delayed active substance release, and method for the preparation thereof
Inventor: HANSHERMANN FRANKE
IPC: A61K31/19
Filed: 2003-05-15
Abstract: Production of a retarded release pharmaceutical composition (A) involves: (a) forming a mixture of active agent (I) and release retarding polymer (II); (b) densifying the mixture by passage between two rollers at a temperature of more than 40 [deg]C under a force of 15-40 kN per cm of roller width; (c) comminuting the densified mixture to the required particle size; and (d) optionally further processing the mixture. An independent claim is included for the composition (A) obtained by the process.
Patent PL-377214-A1 (PL)
Title: Beverage dispensing apparatus
Inventor: YOUNKLE MATTHEW C
IPC: B05B1/02
Filed: 2003-03-14
Abstract: A removable nozzle (201) for attachment to a conventional faucet (203) of a beverage dispensing device to permit the dispensing of a pressurized beverages at a high flow rate without producing excessive foaming comprising a streamlined valve assembly and a downward extending nozzle assembly which permits a range of containers to be filled from the bottom.
Patent PL-396734-A1 (PL)
Inventor: GIERZ LUKASZ
IPC: A01C7/06
Filed: 2011-10-24
Abstract: Przedmiotem wynalazku jest mieszalnik do ziarna z nawozami granulowanymi, majacy zastosowanie w pneumatycznych siewnikach do siewu zbóz. Mieszalnik stanowi dyfuzor (1) w postaci pierscieni (9), oddzielonych od siebie przekladkami (10) i polaczony jest dozownikiem ziarna (4) z zasobnikiem ziarna (3) poprzez zawór (6) i dozownikiem nawozu (5) z zasobnikiem nawozu (2) poprzez zawór (6), natomiast od strony wyjscia rura (13) poprzez zawór (6) z ujsciem ziarna (12), a rura (14) poprzez zawór (6) z ujsciem nawozu (11), ponadto zasobnik nawozu (2) poprzez rure (15) z zaworami (6) polaczony jest z ujsciem nawozu (11), a zasobnik ziarna (3) poprzez rure (16) z zaworami (6) polaczony jest z ujsciem ziarna (12).
Patent PL-399105-A1 (PL)
Inventor: GARSTKA JACEK
IPC: A47F10/00
Filed: 2012-05-07
Abstract: Wynalazek dotyczy regalu grzewczego, znajdujacego zastosowanie w gastronomii. Regal grzewczy posiada korpus (1), utworzony z dwóch pionowych slupków (2), zamontowanych z tylu w narozach. Slupki (2) sa polaczone u dolu z bocznymi sciankami obudowy maszynowni (3), zabudowanej od góry grzewcza plyta (4). Powyzej grzewczej plyty (4) sa zainstalowane na wspornikach pólki o dowolnie regulowanym kacie nachylenia. Po bokach korpus (1) ma przezroczyste oslony. Pólki sa podgrzewane, przy czym pólki oraz grzewcza plyta (4) sa zbudowane z dwóch warstw szklanej plyty, pomiedzy którymi jest zainstalowany grzewczy element.
Patent PL-401850-A1 (PL)
Title: Imak noza tokarskiego
Inventor: PRZESTACKI DAMIAN
IPC: B23B29/04
Filed: 2012-12-03
Abstract: Przedmiotem wynalazku jest imak noza tokarskiego, umozliwiajacy zmniejszenie odleglosci katowej pomiedzy miejscem nagrzewania przedmiotu obrabianego, a miejscem skrawania. Imak przeznaczony jest do stanowisk obróbczych, tj. tokarki zintegrowanej ze zródlem dostarczajacym energie cieplna np. wiazka lasera. Imak noza tokarskiego do obróbki mechanicznej przedmiotów na tokarce z zastosowaniem nagrzewnicy laserowej charakteryzuje sie tym, ze na suporcie (2) tokarki zamocowane sa dwie plyty (1A, 1B), z których kazda ma lukowe rowki ustalajace (3) z gniazdami (6) pod kolek ustalajacy (4), przy czym skrajne gniazda (6) rowków ustalajacych (3) usytuowane sa wzgledem siebie w odleglosci katowej ? w granicach 25-80°, ponadto kazda z plyt (1A, 1B) ma otwory (7) na sruby mocujace (5) do mocowania miedzy plytami (1A, 1B) suportu (2).
Patent PL-402417-A1 (PL)
Inventor: PANDAY RADHIKA
IPC: B23K9/173
Filed: 2011-04-04
Abstract: Podawczy srodek poslizgowy do stosowania na elektrodzie spawalniczej zawiera okolo 10 do 40% wagowych co najmniej jednego srodka poslizgowego na bazie mydla, okolo 40 do 90% wagowych co najmniej jednego srodka poslizgowego w postaci czastek stalych wybranego sposród MoS2, WS2, ZnO, grafitu i PTFE oraz do 20% wagowych co najmniej jednego ewentualnego dodatkowego skladnika poslizgowego w postaci czastek stalych.
Patent PL-403084-A1 (PL)
Inventor: ADAMSKI MARIAN
IPC: G06F11/07
Filed: 2013-03-11
Abstract: Wynalazek dotyczy układu pamięci podwójnej zawierającej dwa jednakowe obszary pamięci (P1, P2). Układ pamięci podwójnej (M) zawiera komparator (K) z jednobitowym portem wyjściowym komparatora i dwoma wielobitowymi portami wejściowymi komparatora: pierwszym (IK1) i drugim (IK2). Pierwszy port wejściowy komparatora (IK1) połączony jest z wielobitowym portem wejściowo-wyjściowym pierwszego obszaru pamięci (IOP1), zaś drugi port wejściowy komparatora (IK2) połączony jest z wielobitowym portem wejściowo-wyjściowym drugiego obszaru pamięci (IOP2).
Patent PL-403207-A1 (PL)
Inventor: TOMASZEWSKI HENRYK
IPC: B01J21/06
Filed: 2013-03-18
Abstract: Przedmiotem wynalazku jest sposób wytwarzania warstw dwutlenku tytanu o właściwościach hydrofilnych, fotokatalitycznych i bakteriobójczych, zwłaszcza na podłożach ceramicznych i szklanych. Wynalazek ma zastosowanie do oczyszczania powietrza ze szkodliwych dla zdrowia ludzkiego lotnych związków organicznych, do oczyszczania wody, do otrzymywania wyrobów zdolnych do samomycia i samooczyszczania oraz w szpitalnictwie w odniesieniu do szczepów bakteryjnych obecnych w skażeniach szpitalnych. Sposób polega na tym, że w komorze osadzania umieszcza się target ceramiczny TiO2-x, gdzie x=0-1,0, w odległości 1-15cm od pokrywanego podłoża, po czym przez komorę przepuszcza się gaz obojętny, utrzymując jego przepływ w granicach 1,0-15,0cm3/min oraz ciśnienie w komorze 1,0-8,0x10-2 mbarów i następnie prowadzi się proces osadzania warstwy dwutlenku tytanu metodą rozpylania jonowego przy gęstości mocy 1,0-10,0 W/cm2 do osiągnięcia żądanej grubości warstwy.
Patent PL-403650-A1 (PL)
Inventor: PIECHOTA RYSZARD
IPC: B04C5/00
Filed: 2013-04-24
Abstract: Przedmiotem wynalazku jest multicyklon osiowy - trójstrumieniowy do odpylania gazów, gdzie gazy po zawirowaniu na zawirowywaczach, rozdzielane są w obszarze części zbiornikowej na trzy strumienie: osiowy (1), lewy (2) i prawy (3), a ponadto zawirowywacze w części lewej multicyklonu, wymuszają skręt lewy (4) strumieni gazów, a części prawej skręt prawy (5) strumieni.
Patent PL-404167-A1 (PL)
Title: Płatek kosmetyczny nawilżany i włóknina z której ten płatek jest wycinany
Inventor: GAŁWIACZEK ARTUR
IPC: A61Q19/00
Filed: 2013-05-31
Abstract: Przedmiotem wynalazku jest płatek kosmetyczny nawilżany i włóknina, z której ten płatek jest wycinany. Płatek jest nawilżany bezwodnym płynem na bazie oleju. Warstwy licowe (1) i (2) płatka i włókniny zawierają włókna celulozowe hydrofobowe Tencel Biosoft lub jego odpowiedniki o znacznej absorpcji substancji oleistych
Patent PL-404462-A1 (PL)
Title: Sposób wytwarzania optycznie czystego (-)-(S)-6,4'-dihydroksyflawanonu
Inventor: KOSTRZEWA-SUSLOW EDYTA
IPC: C12P17/06
Filed: 2013-06-26
Abstract: Sposób wytwarzania optycznie czystego (-)-(S)-6,4'-dihydroksyflawanonu, o wzorze 2, polega na tym, ze na przygotowana pozywke wprowadza sie szczep Aspergillus niger MB i w momencie osiagniecia przez grzyb koncowej fazy logarytmicznego wzrostu, dodaje sie 6-butyryloksyflawanon w ilosci 10 mg na 100 ml pozywki, przy czym proces transformacji mikrobiologicznej prowadzi sie wodna kultura szczepu przy ciaglym wstrzasaniu, w wyniku czego, przy udziale systemu enzymatycznego szczepu, nastepuje hydroliza wiazania estrowego w pozycji 6, a nastepnie hydroksylacja w pozycji 4' substratu 6-butyryloksyflawanonu. Otrzymany produkt ekstrahuje sie rozpuszczalnikiem organicznym niemieszajacym sie z woda i oczyszcza chromatograficznie.