baber/WOPTO huggingface dataset:
Patent NZ-611323-A (NZ)
Title: Cyclopropyl amine derivatives as histamin h3 receptor modulators
Inventor: LIU HUAQING
IPC: C07D495/04
Filed: 2007-06-22
Abstract: Disclosed are 1-phenyl-2-aminoalkyl-cyclopropane derivatives as represented by the general formula (I), or a pharmaceutically acceptable salt, ester, or amide thereof, wherein the substituents are as defined in the specification. Representative compounds include 2-methyl-5-[4-((1S,2S)-2-{ [(2S)-2-methylpyrrolidin-1-yl]methyl} cyclopropyl)phenyl]-1,3-benzothiazole; N-[4-((1S,2S)-2-{ [(2S)-2-methylpyrrolidin-1-yl]methyl} cyclopropyl)phenyl]-5-(trifluoromethyl)thieno[3,2-b]pyridine-6-carboxamide, or a salt thereof. Further disclosed is a composition comprising a compound as defined above, and a pharmaceutically acceptable carrier; for the treatment of conditions such as attention-deficit hyperactivity disorder (ADHD), deficits in attention, dementia, and diseases with deficits of memory, learning, schizophrenia, cognitive deficits of schizophrenia, cognitive deficits and dysfunction in psychiatric disorders, Alzheimer’s disease, mild cognitive impairment, epilepsy, seizures, allergic rhinitis, and asthma, motion sickness, dizziness, Meniere’s disease, vestibular disorders, vertigo, obesity, diabetes, type II diabetes, Syndrome X, insulin resistance syndrome, metabolic syndrome, pain, including neuropathic pain, neuropathy, sleep disorders, narcolepsy, pathological sleepiness, jet lag, drug abuse, mood alteration, bipolar disorder, depression, obsessive compulsive disorder, Tourette’s syndrome, Parkinson’s disease, and medullary thyroid carcinoma, melanoma, and polycystic ovary syndrome.
Patent NZ-612461-A (NZ)
Title: Method and apparatus for marking manufactured items
Inventor: CHATELAIN PHILIPPE
IPC: G06Q10/00
Filed: 2011-12-21
Abstract: There is provided a method and apparatus for marking manufactured items. The method comprises providing a cryptographic key (211), in an inactive state, to a point in a supply chain for the manufactured items, providing the cryptographic key (209), in an active state, and an activation code (213) for activating the cryptographic key, to a verification centre (114), and providing the activation code to the point in the supply chain in response to the point in the supply chain transmitting information relating to the received cryptographic key (209, 211). The activation code (213) allows the cryptographic key (211) in the inactive state to be activated to form the cryptographic key (209) in the active state, wherein the verification centre is structured to encrypt the activation code with a public key of an asymmetric key pair associated with a certificate of the cryptographic key. The method further comprises generating, at the point in the supply chain, an identification (ID) code for each manufactured item. The ID code is derived from the cryptographic key in the active state and a dynamic key generated for each batch of manufactured items. The method further comprises providing the dynamic key for each batch of manufactured items to the verification centre, marking each manufactured item with the ID code, and counting the actual or correct number of ID codes marked on the manufactured items.
Patent NZ-617413-A (NZ)
Title: Method for physically working and/or heating media, in particular liquids, and device for carrying out the method
Inventor: GREGA SAMUEL
IPC: C02F1/48
Filed: 2012-05-03
Abstract: The disclosure relates to a method for physically working and/or heating media, in particular liquids. The method relates to ionisation or polarization of a fluid media followed by exposure to electromagnetic radiation. The disclosure also relates to an apparatus for performing the method
Patent NZ-618219-A (NZ)
Title: Polymer encapsulated non-polymeric particulate material
Inventor: HAWKETT BRIAN STANLEY
IPC: C09C3/10
Filed: 2012-05-31
Abstract: Disclosed is a polymer encapsulated particulate material comprising: a particulate material, a water swellable polymer layer that encapsulates the particulate material capable of changing in volume in response to the presence or absence of water; and an extendable water permeable polymer layer that encapsulates the water swellable polymer layer and stretches to accommodate the volume changes of said water swellable polymer layer. Also disclosed is a method of producing an aqueous dispersion of the polymer encapsulated particulate material comprising: providing a dispersion of the particulate material in a continuous aqueous phase, the dispersion comprising ethylenically unsaturated monomer and a stabiliser; and (a) polymerising a monomer composition that includes ionisable ethylenically unsaturated monomer so as to form the base responsive water swellable non-living polymer layer that encapsulates the particulate material; and (b) polymerising a monomer composition that includes non-ionisable ethylenically unsaturated monomer so as to form the extensible, water and base permeable non-living polymer layer that encapsulates the base responsive water swellable polymer layer. Examples of the ionisable ethylenically unsaturated monomer used to form the water swellable polymer layer are: Methyl methacrylate (MMA), butyl acrylate (BA) and methacrylic acid (MA), and/or acrylic acid (AA). Examples of the non-ionisable ethylenically unsaturated monomer used to form the extendable water permeable polymer layer are: Styrene, methyl methacrylate, and butyl acrylate.
Patent NZ-622017-A (NZ)
Title: Agricultural and horticultural fungicidal composition
Inventor: KUWAHARA RAITO
IPC: A01P3/00
Filed: 2012-09-24
Abstract: The present disclosure provides an agricultural and horticultural bactericide composition comprising at least one compound (A) which is selected from a nitrogenated heterocyclic compound having a specific structure including a compound represented by formula (1) or formula (2) and a salt of the nitrogenated heterocyclic compound and at least one compound (B) which is selected from a specific agrichemically active compound group. [In formula (1), X’s independently represent a halogeno group or a C1-6 alkyl group; n is the number of X’s and represents an integer of 0-6; X’ represents a halogeno group; and R1, R2 and R independently represent a C1-6 alkyl group or a hydroxy group.]
Patent NZ-624957-A (NZ)
Title: Stationary coil and recessed lighting fixture
Inventor: YI-PO HUANG
IPC: F21V29/00
Filed: 2014-05-13
Abstract: A stationary coil (see also 10, figure 2), adapted to displace ceiling fireproof foam or insulation (110) away from a heat dissipation module (see also 21, figure 2), such as a heatsink, of a recessed lighting fixture is disclosed. The stationary coil comprises a bottom end (see 11, figure 1) adapted to be connected to one side of the heat dissipation module, a coiled portion (see 12, figure 2) adapted to coil upward along an outer edge of the heat dissipation module from the bottom end and forming a top surface (13) above the top end (211) of the illumination main body, and a supporting portion extending downward from the top surface. The supporting portion comprises a supporting element (141) and a connecting element (142). The supporting element is connected to the top surface and the connecting element is connected to the top end of the illumination main body to form an interval (h1) between the top surface and the top end. The stationary coil advantageously displaces surrounding fireproof foam (110), or insulation, from around the heat dissipation module to allow sufficient dissipation of heat.
Patent NZ-702644-A (NZ)
Title: Delivery of respiratory therapy
Inventor: KWOK PHILIP RODNEY
IPC: A61M16/08
Filed: 2007-07-27
Abstract: A patient interface comprising: a first loop (LP1) adapted to pass along an underside of a patient’s nose, along the cheek region, above the ears, and over the crown of the patient’s head to define a sealing force against the underside of the patient’s nose in use; and a second loop (LP2) connected to the first loop, the second loop adapted to pass generally over the occipital bone to define a headgear vector at an angle (alpha) between 40°-80° with the first loop in use.
Patent NZ-703689-A (NZ)
Title: Humanized non-human animals with restricted immunoglobulin heavy chain loci
Inventor: MACDONALD LYNN
IPC: C07K16/46
Filed: 2013-03-07
Abstract: Mice, embryos, cells, and tissues having a restricted immunoglobulin heavy chain locus and an ectopic sequence encoding one or more ADAM6 proteins are provided, in various embodiments, mice are described that have humanized endogenous immunoglobulin heavy chain loci and are capable of expressing an ADAM6 protein or ortholog or homolog or functional fragment thereof that is functional in a male mouse. Mice, embryos, cells, and tissues having an immunoglobulin heavy chain locus characterized by a single human VH gene segment, a plurality of human DH gene segments and a plurality of human JH gene segments and capable expressing an ADAM6 protein or ortholog or homolog or functional fragment thereof are also provided.
Patent NZ-706387-A (NZ)
Title: Synergistic weed control from applications of aminocyclopyrachlor and aminopyralid
Inventor: MANN RICHARD K
IPC: A01N43/48
Filed: 2013-09-27
Abstract: Disclosed herein are herbicidal compositions comprising a synergistically herbicidal effective amount of (a) aminocyclopyrachlor, or an agriculturally acceptable salt or ester thereof, and (b) aminopyralid, or an agriculturally acceptable salt or ester thereof. Also disclosed herein are methods of controlling undesirable vegetation, which comprise applying to vegetation or an area adjacent the vegetation or applying to soil or water to prevent the emergence or growth of vegetation (a) aminocyclopyrachlor, or an agriculturally acceptable salt or ester thereof, and (b) aminopyralid, or an agriculturally acceptable salt or ester thereof, wherein (a) and (b) are each added in an amount sufficient to produce a synergistic herbicidal effect.
Patent NZ-709318-A (NZ)
Title: Antibody constructs for cdh19 and cd3
Inventor: KING CHADWICK TERENCE
IPC: A61K39/395
Filed: 2014-01-27
Abstract: Metastatic melanoma has a poor prognosis, with a 5 year relative survival of 15%. The present invention provides to an antibody construct comprising a first human binding domain capable of binding to human CDH19 on the surface of a target melanoma cell and a second domain capable of binding to human CD3 on the surface of a T cell for use in treating melanoma. Moreover, the invention relates to a nucleic acid sequence encoding the antibody construct, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention relates a process for the production of the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct.
Patent NZ-712576-A (NZ)
Title: Dna-pk inhibitors
Inventor: COURT JOHN
IPC: C07D417/12
Filed: 2014-03-12
Abstract: The present invention relates to compounds (I) useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
Patent NZ-712598-A (NZ)
Title: Culture method to obtain and maintain a pure or enriched population of mammalian neural stem cells and/or neural progenitor cells that are prone to differentiate into oligodendrocyte-lineage cells in vitro
Inventor: KIDO TSUNEO
IPC: C12N5/0797
Filed: 2012-01-12
Abstract: Disclosed is a method of in vitro culturing and maintaining an expandable neural cell wherein the cell is a progenitor cell or stem cell and wherein the cell maintains its capability to differentiate into neurons, astrocytes, and oligodendrocytes and its ability to differentiate into oligodendrocyte-lineage cells efficiently, the method comprising: a) providing at least one cell which has been isolated and dissociated from a human fetal neural tissue; b) culturing the cell at a temperature of 37°C, in an atmosphere comprising 1-20% O2, and 5% CO2, and in a chemically defined serum-free culture medium, wherein the medium comprises: -at least 5 ng/ml PDGF-AA, -at least 0.5 ng/ml bFGF, and -at least 10 μM 1-thioglycerol; c) passaging the cell from b) to obtain the expandable human neural cell. Also disclosed is an in vitro culture comprising an enriched population of neural cells which have been isolated from a mammalian central nervous system wherein the isolated cell is submerged in chemically defined serum-free culture medium comprising: - at least 5 ng/ml PDGF-AA, - at least 5 ng/ml bFGF, and - at least 10 μM 1-thioglycerol.
Patent NZ-713887-A (NZ)
Title: External ear canal pressure regulation system
Inventor: GEORGE DAVID
IPC: A61M13/00
Filed: 2014-06-27
Abstract: Pain or discomfort associated with a disorder, including neurologically-mediated disorders such as craniofacial pain syndromes or headache syndromes, may negatively impact the quality of life of the sufferer. In addition to the burden upon the individual, chronic neurological conditions may be a significant strain upon family members, employers, and the healthcare system. There would be a substantial advantage in providing a device or methods which can generate one or more stimuli which can alleviate one or more symptoms associated with a disorder, such as craniofacial pain syndromes or headache syndromes, or treat one or more disorders. An external ear canal pressure regulation device comprises a first fluid flow generator capable of generating a first fluid flow; a first earpiece having a first earpiece axial conduit which communicates between first earpiece first and second ends, said first earpiece axial conduit fluidicly coupled to said first fluid flow generator, said first earpiece having a first earpiece compliant external surface configured to sealably engage a first external ear canal of a first ear as a first barrier between a first external ear canal pressure and an ambient pressure, said first fluid flow generator capable of generating a first pressure differential between said first external ear canal pressure and said ambient pressure, said first pressure differential comprising a first pressure differential amplitude; a first pressure sensor which generates a first pressure sensor signal which varies based upon change in a first pressure differential amplitude; and a first pressure signal analyser. The first pressure signal analyser comprises a first pressure differential amplitude comparator which compares a preselected first pressure differential amplitude to said first pressure differential amplitude, said first pressure sensor signal analyzer generating a first pressure differential amplitude compensation signal to which a first fluid flow generator controller is responsive to control said first fluid flow generator to achieve said pre-selected first pressure differential amplitude.
Patent NZ-716013-A (NZ)
Title: On-shelf tracking (ost) system
Inventor: CAMPBELL PATRICK
IPC: G08B5/22
Filed: 2012-03-16
Abstract: A system to be installed on a merchandising unit having one or more inventory zones, one or more units of product, one or more product sensors, a mounting structure, and an electromagnetic signal processor. The one or more inventory zones can present the one or more units of product in several different arrangements. The one or more product sensors, each associated operatively with one of the one or more inventory zones, converts a sensed number of the one or more units of product into a respective analog electromagnetic signal. The mounting structure secures the one or more product sensors to the merchandising unit relative to the one or more units of product so that the one or more product sensors sense a number of the one or more units of product. The electromagnetic signal processor in communication with the one or more product sensors can sample output from the one or more product sensors periodically and converts the analog signal into a digital signal.
Patent NZ-718117-A (NZ)
Title: Optimal soybean loci
Inventor: WEBB STEVEN R
IPC: C12N15/87
Filed: 2014-11-03
Abstract: As disclosed herein, optimal native genomic loci of soybean plants have been identified that represent best sites for targeted insertion of exogenous sequences.
Patent NZ-721756-A (NZ)
Title: Pesticidal fusion protein improvements
Inventor: FITCHES ELAINE CHARLOTTE
IPC: A01P17/00
Filed: 2014-12-11
Abstract: Methods of increasing the biological activity of toxins. Methods of increasing the biological activity of pesticide toxins through the incorporation of pro-regions into nucleic acid constructs for the production of said toxins. In a specific embodiment includes a method of increasing the biological activity of a recombinant toxin, the method comprising: providing a nucleic acid construct comprising: (i) an arthropod toxin encoding sequence, or a sequence of a biologically active fragment or variant thereof, the variant retaining at least 50% of the biological activity of the arthropod toxin and having a nucleic acid sequence which has at least 75% identity to the arthropod toxin sequence, operably linked to (ii) a nucleic acid sequence encoding a pro-region, wherein the pro-region is a sequence between a signal peptide sequence and a mature protein N-terminus; and (iii) a nucleic acid sequence encoding a carrier protein, or a fragment or variant thereof, which is capable of mediating translocation of a fusion protein comprising the arthropod toxin or the biologically active fragment or variant thereof linked to the carrier protein, or the fragment or variant thereof, from an invertebrate gut.
Patent NZ-723522-A (NZ)
Title: Structure of the filter assembly of a beeswax separation screw
Inventor: VAARA JUHANI
IPC: A01K59/06
Filed: 2015-01-23
Abstract: The figure FIG 1 shows the present invention of the new structure of the filter assembly of the beeswax separation screw 1 that comprises cylindrical filter components 2,3,4 attached to each other one after the other. One of these cylindrical filter components composes of a cylindrical filter pipe 5, at the ends of which there are mounted flanges 6. The filter components 2, 3 and 4 are tightly attached one after the other with bolts so that the opposite flanges of the filter components 2, 3, 4 mounted one after the other settle against each other. The first filter component 4 of the structure 1 is open at its top under the feed hopper 7 and the following filter components 3 and 2 are closed, the sides of said filter components 2,3 and 4 having small holes on them, through which the increasing pressure forces the honey out. The other end of the filter component 4 Is mounted to the body of the beeswax separation screw with bolts. The structure 1 is beneficial also when composed of only two filter components 4 and 2, mounted one after the other, in case of which the filter component 4 comprises the whole length of the compression zone. The problem the invention is dealing with is in traditional machines needing to have different parts (auger) for different viscosity of honey and wax combinations. Also to improve cleaning and maintenance of the device. The present invention overcomes this by the bolt flanges that can be undone to allow removal of parts. Different beeswax and honey has different consistence and there is a problem of how to separate this easily. The device has a compression zone that gradually adds more pressure for different consistencies.
Patent NZ-725044-A (NZ)
Title: Compounds and compositions for inducing chondrogenesis
Inventor: CHOI HA-SOON
IPC: A61K31/44
Filed: 2015-05-12
Abstract: The present invention provides compounds of formula IA, or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds, and methods of using such compounds for treatment of joint damage or joint injury in a mammal, and for inducing differentiation of mesenchymal stem cells into chondrocytes.
Patent NZ-728493-A (NZ)
Title: A packaging system
Inventor: COOK HUBERT
IPC: B65B61/00
Filed: 2015-07-22
Abstract: In food services, a dispensing device may be used to discharge one or more condiments and such devices may contain separate containers which house different condiments. However these devices are typically time consuming to clean and refill. Preferred embodiments of the present invention seek to provide a packaging system comprising: a) a container comprising first and second openings and an interior; b) a package positioned within the container interior, the package comprising a pouch comprising a front sheet and a rear sheet with a frangible seal positioned between the front and rear sheets, and a flowable product disposed in the pouch; and c) a dispensing assembly, wherein the frangible seal comprises: d) a single label with a first face and a second face, the first face comprising a permanent sealant and the second face comprising a peelable sealant; or e) first and second labels, each label comprising: a first face, wherein the first face of the first label comprises a permanent sealant positioned adjacent the pouch front sheet and wherein the first face of the second label comprises a permanent sealant positioned adjacent to the pouch rear sheet; and a second face, wherein the second face of the first label comprises a peelable sealant positioned adjacent to the second label second face, and/or wherein the second face of the second label comprises a peelable sealant positioned adjacent to the first label second face.
Patent NZ-739482-A (NZ)
Title: An apparatus for mixing and delivering bone cement
Inventor: FOSTER DAVID
IPC: B01F15/02
Filed: 2014-03-18
Abstract: Orthopaedic bone cement is used throughout the world to secure hip, knee and other metallic prostheses in an appropriate medical position. Also, bone cement can be used to replace and/or repair damaged bone, such as a bone void filling and spinal column with degenerative intervertebral discs by permanently stabilising adjacent vertabrae by fusion. Cement may be applied by hand or may be put into a syringe and applied separately. However, this simple mixing has two major drawbacks. Firstly, free methylmethacrylate fumes are emitted from the mixture. Secondly, a very high mixing efficiency is required to produce a homogenous cement material. The specification discloses a device for mixing bone cement material. The device has a mixing body with a chamber, a first end, and a second end. The device has a lid arranged to be fitted to the first end. The device also has means for mixing bone cement material in the chamber, the means for mixing comprising a rod extending through the lid and into the chamber. The device also has means for dispensing bone cement material from said mixing body attached to a second end of the mixing body. The means for dispensing the bone cement material is a plunger movable by the application of force through the chamber. The plunger is provided to set an adjustable volume in the chamber prior to mixing. The device also has means for positioning the plunger between the first and the second end of the mixing body to define a volume of the chamber, and means for maintaining the position of the plunger so as to maintain the volume of the chamber during mixing. The means for positioning the plunger and means for maintaining the position of the plunger comprises a screw thread arranged on an outer surface of the plunger, and a nut having a screw thread to be received by the screw thread arranged on the outer surface of the plunger. The nut also has a recess having a screw thread to be received by a screw thread located at the second end of the mixing body.