baber/WOPTO huggingface dataset:
Patent EP-4153192-A1 (EP)
Inventor: RODRIGUEZ RAPHAËL
IPC: C07K16/28
Filed: 2021-05-19
Abstract: The invention relates to methods and pharmaceutical compositions for the treatment of Cytokine Release Syndrome (CRS). The invention also relates to methods for the diagnosis of patients suffering from Cytokine Release Syndrome. The inventors investigate iron homeostasis and the role of CD44-mediated iron endocytosis in the severe inflammatory response and Cytokine Release Syndrome, particularly in SARS-CoV-2 patients. The inventors demonstrate that during activation of Ml macrophages, iron endocytosis is upregulated in a CD44- dependent manner and that CD44 protein levels increase. This effect is specific to Ml macrophages, whereas levels of the canonical iron endocytosis protein TfRl/CD71 remain unchanged. In the present invention, the inventors provide in vitro evidences towards a direct role of CD44-mediated iron endocytosis in the severe inflammatory response such as Cytokine Release Syndrome observed in SARS-CoV-2 patients. Thus, the present invention relates to an antagonist of CD44/Hyaluronic Acid pathway for use in the treatment of cytokine release syndrome in a subject in need thereof, particularly severe CO VID- 19-related cytokine release syndrome.
Patent EP-3916096-A1 (EP)
Inventor: LEE JI HYUN
IPC: C12N15/77
Filed: 2021-02-19
Abstract: Provided are a microorganism of the genus Corynebacterium which produces a purine nucleotide, and a method of producing a purine nucleotide using the microorganism.
Patent EP-4150210-A1 (EP)
Inventor: FRANCAVILLA MATTEO
IPC: F03G3/00
Filed: 2021-05-11
Abstract: A system for energy conversion comprises a support structure (2) which has a descent channel (3) and an ascent channel (4) connected at respective lower ends and a sealing device (10) applied at the upper end of the descent channel (3). The system further comprises at least one extensible element (E), switchable between a compressed configuration and a dilated configuration and sliding inside the support structure (2) along a path extending from the descent channel (3) to the ascent channel (4). The system further comprises a plurality of locking means (8) configured to individually and reversibly constrain respective portions of the extensible element (E) to the support structure (2).
Patent EP-4164532-A1 (EP)
Inventor: PAPINI ILAN MEIR
IPC: A61B18/14
Filed: 2021-06-10
Abstract: L'invention concerne un mécanisme pour générer au moins deux indicateurs de contact indiquant si un ballonnet gonflable d'un cathéter de thérapie par ballonnet est en contact avec les limites d'une cavité anatomique. Le mécanisme obtient un modèle anatomique de la cavité anatomique, détermine un emplacement d'un cathéter de thérapie par ballonnet par rapport à la cavité anatomique, et utilise ces informations, conjointement avec une ou plusieurs propriétés géométriques du ballonnet gonflable, pour dériver les deux indicateurs de contact ou plus.
Patent EP-4118310-A1 (EP)
Title: Twin-jet piston cooling nozzle made of plastic material
Inventor: PEROTTO STÉPHANE PASCAL
IPC: F01M1/08
Filed: 2021-04-21
Abstract: Disclosed is a fluid nozzle, in particular for an engine piston cooling fluid, comprising a hollow supply body (11) which is connected to a conduit structure (15) provided with a free end (15.2) forming a discharge end provided with orifices (17a, 17b) for discharging the fluid, the supply body and the conduit structure forming a single piece made of plastic material.
Patent EP-4211515-A1 (EP)
Inventor: BERTHEVILLE BERNARD
IPC: G04B37/22
Filed: 2021-07-07
Abstract: L'invention concerne un article décoratif réalisé dans un matériau cermet comportant en poids entre 70 et 97% d'une phase céramique et entre 3 et 30% d'une phase d'un liant métallique, le liant métallique comprenant au moins un élément ou son alliage choisi parmi la liste constituée du ruthénium, du rhodium, du palladium, de l'osmium, de l'iridium, du platine, de l'or et de l'argent, la phase céramique comportant une phase de nitrures et optionnellement une phase d'oxydes et/ou d'oxynitrures, ladite phase de nitrures étant présente, par rapport au poids total du matériau cermet, dans un pourcentage compris entre 70 et 97% et ladite phase d'oxydes et/ou d'oxynitrures dans un pourcentage compris entre 0 et 15%. La présente invention se rapporte également au procédé mis en oeuvre pour réaliser cet article.
Patent EP-4087851-A1 (EP)
Inventor: SZOSTAK MICHAL
IPC: B01J31/00
Filed: 2021-01-08
Abstract: L'invention concerne une nouvelle classe de complexes Pd(II)-NHC hautement actifs portant des anilines en tant que ligands jetables. Ces catalyseurs sont bien définis, stables à l'air et à l'humidité et peuvent être facilement purifiés par des techniques chromatographiques. Une activité et une généralité élevées ont été illustrées dans le couplage croisé de Suzuki-Miyaura par clivage de C-N, C-O et C-Cl. L'invention concerne également des synthèses faciles de ces catalyseurs.
Patent EP-4186337-A1 (EP)
Inventor: RIVA REGGIORI RICCARDO
IPC: A24F40/57
Filed: 2021-07-19
Abstract: L'invention concerne un dispositif de génération d'aérosol (100) qui comprend une première source d'alimentation (120), un dispositif d'aérosolisation (110) configuré pour recevoir de l'énergie provenant de la première source d'alimentation et configuré pour générer un aérosol à partir d'un substrat de génération d'aérosol (170), une seconde source d'alimentation (130) et un circuit de chauffage (160) conçu pour recevoir de l'énergie provenant de la seconde source d'alimentation afin de chauffer la première source d'alimentation.
Patent EP-4189560-A1 (EP)
Inventor: ARCHIMBAUD AURORE
IPC: H01L21/00
Filed: 2021-08-03
Abstract: L'invention concerne un procédé de détermination du niveau d'atypicité d'individus, permettant notamment de détecter statistiquement des individus atypiques dans un jeu de données préalablement récoltées, issues de mesures de paramètres d'individus réalisées par une pluralité de systèmes de mesures, caractérisé en ce qu'il comporte les étapes de : - prétraitement 100 des données; - détermination 200 d'un indice d'atypicité multivarié, ledit indice étant transformé par une fonction f pour être compris entre 0 et 1, sur l'ensemble des mesures pour chaque individu, à partir des données prétraitées; - Identification 300 des individus atypiques.
Patent EP-4185340-A1 (EP)
Title: Nanoparticles, nanofunctionalised substrate and device with antiviral and/or antibacterial and/or antifungal photocatalytic activity
Inventor: BALDI GIOVANNI
IPC: A61L9/00
Filed: 2021-07-22
Abstract: The invention relates to the use of nitrogen-doped TiO2 (TiO2-N) nanoparticles activatable by UV light and/or visible light and/or sunlight, of a substrate nanofunctionalised with said nanoparticles and of a device comprising said substrate and at least one light source configured to emit radiation having a wavelength comprised between 10 and 1500 nm, for killing a virus and/or fungi and/or bacteria. The invention also relates to a method for killing said virus and/or said fungi and/or said bacteria, comprising the steps of: (A) providing said nanoparticles or (A') said substrate or (A") said device; (B) placing said nanoparticles or (B') said substrate or (B") said device in contact with said virus and/or said fungi and/or said bacteria; and (C) irradiating said nanoparticles or (C')/(C") said substrate with a source of UV light and/or visible light and/or sunlight.
Patent EP-4108449-A1 (EP)
Inventor: YAMAZAKI ATSUSHI
IPC: B32B27/36
Filed: 2021-02-16
Abstract: The laminated film comprising a coating layer and an inorganic thin film layer on one surface of a substrate film, wherein the laminated film satisfies the following requirements (a) to (f):(a) the substrate film contains 50% by weight or more and 95% by weight or less of a polyester resin recycled from PET bottles;(b) a surface hardness of an inorganic thin film layer surface of the laminated film is 120 N/mm<sup>2</sup> or less;(c) the coating layer contains a resin having an oxazoline group or a carbodiimide group as a constituent component;(d) a content rate of an isophthalic acid component relative to a total dicarboxylic acid component in a whole polyester resin constituting the substrate film is 0.5 mol% or more and 5.0 mol% or less;(e) both a coefficient of static friction µs and a coefficient of dynamic friction µd of the inorganic thin film layer surface/an opposite surface of the laminated film are within a range of 0.20 to 0.40; and(f) an arithmetic average roughness Ra of the laminated film in a 2-µm square range is within a range of 2.0 to 6.0 nm.
Patent EP-4109062-A1 (EP)
Inventor: FUJITA TOSHIAKI
IPC: H01L37/00
Filed: 2021-02-17
Abstract: Provided is a heat flow switching element that has a larger change in thermal conductivity, has excellent thermal responsiveness, and is capable of directly detecting a temperature change. The heat flow switching element according to the present invention includes: a heat flow control element part 10 including an N-type semiconductor layer 3, an insulator layer 4 laminated on the N-type semiconductor layer, and a P-type semiconductor layer 5 laminated on the insulator layer; and thermosensitive element parts 11A and 11B joined to the heat flow control element part. In addition, the thermosensitive element parts include: a thin-film thermistor portion made of a thermistor material; and a pair of counter electrodes formed facing each other on an upper side and/or a lower side of the thin-film thermistor portion, and the thin-film thermistor portion is laminated on an upper side and/or a lower side of the heat flow control element part.
Patent EP-4108523-A1 (EP)
Title: Vehicle light
Inventor: MOCHIZUKI MITSUYUKI
IPC: F21Y115/30
Filed: 2021-02-15
Abstract: The vehicle lamp includes a first lamp unit and a second lamp unit each including a first light source configured to emit an emission beam (visible light), a second light source configured to emit infrared light for sensing having a peak wavelength different from that of the first light source, and a light receiving unit configured to detect an intensity of reflected light of the infrared light emitted from the second light source. The light distribution control is performed on the light emitted from the first light source in accordance with the intensity of the reflected light detected by the light receiving unit, and the peak wavelength of the light emitted from the second light source of the first lamp unit and the peak wavelength of the light emitted from the second light source of the second lamp unit are different from each other.
Patent EP-4211920-A1 (EP)
Title: Evaluating effect of a change made in a communication network
Inventor: LUNDÉN PETTERI
IPC: H04W24/02
Filed: 2021-08-23
Abstract: A computer implemented method for evaluating effect of a change made in a communication network. The method is performed by comparing (302) values of the performance indicator in a cell of interest before and after the change to obtain a first comparison result; comparing (304) values of the performance indicator in a set of reference cells before and after the change to obtain a second comparison result; and evaluating (305) the effect of the change made in the communication network based on difference between the first comparison result and the second comparison result.
Patent EP-4101725-A1 (EP)
Title: Braking system for continental railroad vehicle
Inventor: MUN HYUNG-SUK
IPC: B61H13/34
Filed: 2021-06-01
Abstract: A braking system for a railroad car is proposed. The braking system includes both standard gauge and broad gauge distribution valves that are different types and, and is able to automatically supply a braking pneumatic pressure, which is suitable for braking systems that are applied in different ways in accordance with gauges, without stopping railroad cars by switching a braking pneumatic pressure such that the braking pneumatic pressure is supplied to a distribution valve, which is used for a corresponding gauge of the different types of distribution valves, by movement of wheels at a gauge change section.
Patent EP-4092034-A1 (EP)
Title: Novel compound and organic light-emitting device using same
Inventor: LIM BYEONG YUN
IPC: H01L51/50
Filed: 2021-02-17
Abstract: The present disclosure provides a novel compound and an organic light emitting device including the same.
Patent EP-4122877-A1 (EP)
Title: Fuel cell system
Inventor: TAMURA YOSHIO
IPC: H01M8/0662
Filed: 2021-01-19
Abstract: The present disclosure provides a fuel cell system (100) to which raw material hydrogen containing hydrogen, nitrogen, and carbon monoxide is externally supplied, the fuel cell system (100) including: a carbon monoxide removing unit (1, 2) configured to remove part of the carbon monoxide from the raw material hydrogen to generate a hydrogen-containing gas, and discharge the hydrogen-containing gas; and a first fuel cell (3) configured to generate electric power by using the hydrogen-containing gas. The concentration of the nitrogen contained in the raw material hydrogen is configured to be higher than 25%.
Patent EP-4119549-A1 (EP)
Title: Compound producing method, and compound
Inventor: SUZUKI SHIGERU
IPC: C07D303/48
Filed: 2021-03-09
Abstract: A method by which an intermediate product of an azole derivative can be produced at a lower cost and in a higher yield than those of known production methods is realized. A method of producing a compound of General Formula (III) includes: producing the compound of General Formula (III) by allowing a cyanide compound to act on a ketone derivative of General Formula (II); and washing the compound of General Formula (III) produced in the producing the compound of General Formula (III) with an alkaline aqueous solution.
Patent EP-4079971-A1 (EP)
Inventor: SHIMIZU MINORU
IPC: G06N3/02
Filed: 2021-03-04
Abstract: A target posture for a work implement at work is determined. There is provided a working system, comprising a body, a work implement attached to the body, and a computer. The computer has a trained target posture estimation model (180) to determine a target posture for the work implement to assume at work. The computer obtains a target value for an amount of a work performed by the work implement, a period of time elapsing since the work implement started to work, and mechanical data for operation of the body and the work implement, uses the trained posture estimation model (180) to estimate a target posture from the target value, the elapsed period of time and the mechanical data, and thus outputs the estimated target posture.
Patent EP-3955344-A1 (EP)
Inventor: KWAK NO WOO
IPC: H01M4/36
Filed: 2021-03-22
Abstract: Provided is a positive electrode active material for a secondary battery which includes a composite coating layer formed on a surface of lithium composite transition metal oxide particles, wherein the composite coating layer includes a ferroelectric material and a boron-based oxide containing boron.
Patent EP-4204272-A1 (EP)
Title: Pneumatische sandfördereinrichtung für ein sandungssystem eines schienenfahrzeugs, sandungssystem und verfahren zum betreiben einer pneumatischen sandfördereinrichtung
Inventor: KRISMANIC GEORG
IPC: B61C15/10
Filed: 2021-08-30
Abstract: Eine pneumatische Sandfördereinrichtung (100) für ein Sandungssystem (500) eines Schienenfahrzeugs umfasst eine Hürdeneinrichtung (105), die fluidisch mit einem Sandeingang (200) zum Aufnehmen von Sand aus einem Sandvorratsbehälter (505) gekoppelt ist, wobei die Hürdeneinrichtung (105) ausgeformt ist, um eine Hürde zwischen dem Sandeingang (200) und einer fluidisch mit der Hürdeneinrichtung (105) gekoppelten Mischeinrichtung (110) zu bilden. Außerdem weist die Sandfördereinrichtung (100) die Mischeinrichtung (110) zum Aufnehmen und Weiterleiten von Sand aus der Hürdeneinrichtung (105) mittels Druckluft auf und eine fluidisch mit der Mischeinrichtung (110) gekoppelte Auslaufeinrichtung (115) zum Ausgeben des Sands aus der Sandfördereinrichtung (100) durch einen Sandausgang (203). Dabei sind die Hürdeneinrichtung (105), die Mischeinrichtung (110) und die Auslaufeinrichtung (115) in einem betriebsbereiten Zustand (140) der Sandfördereinrichtung (100) in einer horizontalen Ebene angeordnet.
Patent EP-4200624-A1 (EP)
Inventor: BLACKBURN MICHAEL JOSEPH
IPC: G01R31/3835
Filed: 2021-08-20
Abstract: A method for operating a medical device includes activating a processor that receives electrical power from a battery in the medical device, measuring a temperature within a housing of the medical device, identifying a low battery voltage threshold based on the temperature, measuring a first voltage level of the battery, commencing an operation sequence after measuring the first voltage level of the battery, generating a plurality of voltage comparisons between a reference voltage level and a voltage level delivered from the battery during the operation sequence, and generating, an output indicating a low battery condition if at least one of the first voltage level of the battery is less than the low battery voltage threshold and above a predetermined minimum operating voltage threshold, or at least one voltage comparison indicating the voltage level of the battery is less than the reference voltage level during the operation sequence.
Patent EP-4225979-A1 (EP)
Title: Tissu léger enduit, notamment pour voile de vol
Inventor: VERAN STÉPHANE
IPC: D03D13/00
Filed: 2021-10-04
Abstract: Tissu pour voile de vol, notamment parapente, formé de fils de chaîne et de fils de trame continus et enduit sur une ou ses deux faces par un polyuréthane (PU), le tissu nu présentant un taux de couverture TC compris entre 1,8 et 4, caractérisé en ce que les fils sont en poly(téréphtalate d'éthylène) (PET), en ce que le tissu a une densité comprise entre 30 et 50 fils/cm en chaîne et en trame, en ce que le polyuréthane est un PU réticulé à base polyéther, polyester ou polycarbonate, et en ce que ce PU est issu de la réticulation (1) d'un polyuréthane monocomposant ayant un module à 100% d'allongement inférieur ou égal à 5 MPa, selon la norme DIN 53504, mis en œuvre en phase solvant organique, (2) par un réticulant, à raison d'une proportion de réticulant sec par rapport à l'élastomère sec compris entre environ 5 % et environ 30% en poids.
Patent EP-4229804-A1 (EP)
Title: Multi-slot reference signal triggering
Inventor: GRANT STEPHEN
IPC: H04L5/00
Filed: 2021-10-12
Abstract: There is provided a network node. The network node being configured to communicate with a wireless device. The network node includes a radio interface and processing circuitry configured to transmit a configuration of a set of reference signals via RRC signaling to the wireless device. The radio interface and processing circuitry are further configured to transmit a downlink control information, DCI, that triggers the set of reference signals in multiple slots to the wireless device. In some embodiments the DCI comprise a field which indicates the number of slots in which the DCI should trigger the set of reference signals. In some further embodiments the RRC signaling configures the set of reference signals in a number of slots. There is also provided a method for a network node, a wireless device and a method for a wireless device.
Patent EP-4143171-A1 (EP)
Inventor: Meiser Emily
IPC: C07D251/44
Filed: 2021-04-28
Abstract: L'invention concerne une composition de soin de la peau topique qui comprend (A) un sucre réducteur, (B) un sulfonate aromatique ayant une surface polaire topologique (tPSA) inférieure à 100 Å2, et (C) un support. L'invention concerne également un procédé d'ajustement de l'aspect de couleur (par exemple, l'angle de teinte, la clarté, la saturation) de la peau, qui implique l'application de la composition de soin de la peau topique sur la peau. La composition de soin de la peau topique permet d'obtenir un bronzage sans soleil profond, riche, durable, avec une tonalité rouge/bronze esthétiquement agréable lorsqu'elle est appliquée sur la peau.
Patent EP-4240439-A1 (EP)
Title: Apparatus for extracorporeal treatment of blood and process of calculating set flow rates in a medical apparatus for extracorporeal treatment of blood
Inventor: POUCHOULIN DOMINIQUE
IPC: A61M1/16
Filed: 2021-10-29
Abstract: A CRRT apparatus comprising a control unit configured to execute a flow-rate setup procedure by receiving a patient prescription comprising clinical prescription parameters, by allowing entry of a set value for a prescribed dialysis dose (D set ) to be delivered, and of a target value for a parameter (nNBL;  Cp 
   HCO3_pat   ) indicative of a steady state acid-base balance in the blood of the patient who has to undergo a CRRT blood treatment, and by determining operating parameters calculating a set value of relevant fluid flow rates including one or more of a fluid flow rate (Q cit ) through the anticoagulant infusion line, a fluid flow rate ( QPBP ) through the PBP infusion line, a fluid flow rate (Q rep.pre ) through the pre-dilution infusion line, a fluid flow rate (Q rep.post ) through the post-dilution infusion line, a fluid flow rate (Q HCO3 ) through the post-dilution bicarbonate infusion line, a fluid flow rate (Q ca ) through the ion balancing infusion line, a blood fluid flow rate (Q b ) through the extracorporeal blood circuit, a fluid flow rate (Q dial ) through the dialysis liquid supply line, and a fluid flow rate (Q eff ) through the effluent fluid line, wherein calculating the set value of the fluid flow rates is based at least on the set value of the prescribed dialysis dose (D set ) and on the target value for the parameter (nNBL;  Cp 
   HCO3_pat   ) indicative of a steady state acid-base balance in the blood.
Patent EP-4247359-A1 (EP)
Inventor: BARRON DENIS MARCEL
IPC: A61K31/352
Filed: 2021-11-18
Abstract: La présente invention concerne un composé de formule générale I destiné à être utilisé dans l'activation de l'AMPK. L'invention concerne également une composition comprenant ledit composé et des procédés d'utilisation de celle-ci, dans l'activation de l'AMPK.
Patent EP-4240522-A1 (EP)
Title: Système de réacteur à lit fixe pour la déshydrogénation oxydante d'éthane
Inventor: GOODARZNIA SHAHIN
IPC: B01J8/02
Filed: 2021-11-05
Abstract: Un système de réacteur à lit fixe pour la déshydrogénation oxydante d'éthane est divulgué, comprenant un lit de catalyseur dans lequel le profil de capacité de catalyse augmente le long de la longueur du lit de catalyseur de l'extrémité amont à l'extrémité aval. Le lit de catalyseur peut comprendre une ou plusieurs sections, à travers un ou plusieurs réacteurs à lit fixe, qui sont identifiées par un changement de capacité de catalyse. La capacité de catalyse, ou la capacité de convertir l'éthane en éthylène, peut être modifiée en changeant le rapport de dilution, la fraction de vide, et ou la température de conversion de 35 %. Un procédé de chargement d'un réacteur à lit fixe avec une capacité de catalyse croissante est également divulgué.
Patent EP-4074634-A1 (EP)
Inventor: JUNG IN SEOP
IPC: H01M50/20
Filed: 2021-06-01
Abstract: The present invention relates to an automatic bolt and nut supply system configured to automatically supply bolts and nuts necessary for each step as much as necessary by type at the time of assembly of a battery pack, the automatic bolt and nut supply system including a plurality of feeders configured to store and supply the bolts and the nuts by type, a conveyance unit configured to convey the bolts and the nuts supplied from the feeders, a reception box configured to receive the bolts and the nuts conveyed by the conveyance unit, and a reception box transfer unit configured to transfer the reception box.