baber/WOPTO huggingface dataset:
Patent MA-38837-A1 (MA)
Title: Inhibiteurs de l'autotaxine contenant un noyau à cycle benzyle-amide cyclique hétéroaromatique
Inventor: SANDHAM DAVID ANDREW
IPC: C07D413/14
Filed: 2014-07-16
Abstract: L'invention concerne de nouveaux composés qui sont des inhibiteurs de l'autotaxine, des procédés de préparation de ces composés, des compositions pharmaceutiques et des médicaments les contenant, ainsi que leur utilisation dans le traitement de maladies et de troubles induits par l'autotaxine.
Patent MA-39320-A1 (MA)
Title: Filtres pour perfuseurs
Inventor: HOLBRO THOMAS
IPC: H04W48/20
Filed: 2015-01-30
Abstract: Dans un réglage de soins aigus, l'apparition rapide des effets thérapeutiques d'un médicament est hautement souhaitable. L'invention concerne des filtres en ligne appropriés pour l'administration rapide d'un agent thérapeutique à base de protéines chargées positivement par l'intermédiaire d'une administration intraveineuse.
Patent UY-24544-A1 (UY)
Title: Composiciones comprendiendo una sal de arilpiperazinil-c2 o c4 alquilen heterociclo y una ciclodextrina
Inventor: SHANKER RAVI MYSORE
IPC: A61K47/48
Filed: 1997-05-06
Abstract: Esta invención se refiere a una composición que contiene una sal de un arilpiperazinil-alquilenoC2 o arilpiperazinil-alquilenoC4 heterociclo (como la ziprasidona) y una ciclodextrina, la cual se utiliza para aumentar la solubilidad. Una composición de una materia que contiene una sal farmacéuticamente aceptable de un compuesto de fórmula (I) y una ciclodestrina, en la que Ar es benzoisotiazolilo o un óxido o un dióxido del mismo, cada uno de ellos opcionalmente sustituido con flúor, cloro, trufluorometilo, metoxi, ciano o nitro; n es 1 ó 2; y X e Y junto con el fenilo al que están unidos forman benzotiazolilo, 2-aminobenzotiazolilo, benzoisotiazolilo, indazolilo, 3-hidroxiindazolilo, indolilo, oxíndolilo opcionalmente sustituido, benzoxazolilo, 2-aminobenzoxazolilo, benzoxazolonilo, 2-aminobenzoxazolinilo, benzotiazolonilo, benzoimidazolonilo o benzotriazolilo. Las ciclodextrinas preferidas son la gamma-ciclodextrina, HPBCD y SBECD. La composición puede contener un complejo de inclusión seco de dicho compuesto formando un complejo con dicha ciclodextrina. El complejo de inclusión sal/ciclodextrina proporciona preferentemente una cantidad de ziprasodona de al menos 2,5 mgA/ml cuando la cantidad de ziprasidona proporcionada por dicho complejo se disuelve en agua al 40% p/v. Se prefieren varias sales de ziprasidona, incluyendo el mesilato, esilato, besilato, tartrato, napsilato y tosilato.
Patent UY-26780-A1 (UY)
Title: Cicloalquil avb3 antagonistas
Inventor: CLARE MICHAEL
IPC: C07D231/38
Filed: 2001-06-15
Abstract: La presente invención se relaciona con una clase de compuestos representados por la fórmula I o una sal farmacéuticamente aceptable de los mismos, composiciones farmacéuticas que comprenden compuestos de la fórmula I y métodos que de manera selectiva inhiben o antagonizan el avB3 y/o avB5 integrin.
Patent UY-29880-A1 (UY)
Title: Composicion para la visibilidad y el impacto de materiales en suspension
Inventor: WISNIEWSKI KAREN
IPC: C11D3/60
Filed: 2006-10-20
Abstract: La invención describe la imagen visual de los materiales suspendidos en una composición líquida.
Patent UY-29883-A1 (UY)
Title: Nuevos beta-agonistas que contienen indol, procedimientos para prepararlos, y su empleo como medicamentos
Inventor: NETHERTON MATTHEW R
IPC: A61P3/00
Filed: 2006-10-25
Abstract: La presente invención se refiere a nuevos beta-agonistas de fórmula general (I) en la cual los radicales R1 y R2 tienen los significados que se indican en las reivindicaciones y en la memoria descriptiva, a sus tautómeros, sus racematos, sus enantiómeros, sus diastereoisómeros, sus solvatos, sus hidratos, sus mezclas, sus profármados y sus sales, en especial sus sales fisiológiacamente aceptables con ácidos o bases inorgánicos u orgánicos, a procedimientos para preparar estos compuestos, y a su empleo como medicamentos con efecto agonistico beta-3 selectivo.
Patent UY-30786-A1 (UY)
Title: Bioacelerador electromagnético
Inventor: CATALA CRISTIAN GOMIS
IPC: B01J19/12
Filed: 2007-12-12
Abstract: La presente invencion se refiere a un bioacelerador electromagnético para la obtencion de biomasa simulando las condiciones ambientales marinas, que comprenden al menos los siguientes elementos: convertidores de biomasa octogonales (1), tanques de reserva de agua de mar (3), filtros de partículas (4), filtros de luz UV (5), tanques de alimentacion y mezcla (6), bombas de alimentacion de presurizacion (8), manometros (9), controladores de presion (10), tanques de compensacion (11), tanques de expansion con válvula de seguridad (12), intercambiadores de calor (13), termostatos de control de temperatura (14), tanques de realimentacion de agua reciclada (15), bombas de reinyeccion (16), centrifugadoras de separacion de biomasa del agua (17), atemperadores (18), paneles de control (25),bombas de recirculacion (26), densímetros (27), sistema de extraccion mecánica de biomasa por centrifugacion (32) y tanques de acumulacion de biomasa (33).
Patent ES-187419-A1 (ES)
Title: PERFECCIONAMIENTOS EN LOS DISPOSITIVOS DE PULVERIZACIoN DE LiQUIDOS
Filed: 1949-03-12
Abstract: Perfeccionamientos en los disopsitivos pulverización de líquidos especialmente sulfatadoras caracterizados por que se dispone un cuerpo de bomba en el que entra un émbolo buzo hueco dotado de un tubo concéntrico de salida y válvula reguladora de aire llevando asimismo el órgano de dispersión.
Patent ES-188444-A1 (ES)
Title: Perfeccionamientos en los dispositivos empleados para el fregado de suelos
Filed: 1949-05-31
Abstract: Perfeccionamientos en los dispositivos empleados para el fregado de suelos caracterizados porque tanto para el lavado del suelo como para el empapado del agua esparcida sobre dicho suelo llevan una masa esponjosa montada de manera amovible en un soporte que consta de dos mandíbulas de las que una es solidaria de un mango y l otra que está articulada sobre la primera es maniobrable a distancia para ejercer sobre la citada masa esponjosa una presión suficiente para asegurar su exprimido.
Patent ES-193308-A1 (ES)
Title: APARATO PARA PRODUCIR FRiO POR SISTEMA DE ABSORCIoN, MEDIANTE CALOR
Filed: 1950-06-05
Abstract: Aparato para producir frío por sistema de absorción mediante calor caracterizado porque consta de un calderín o depósito que tiene por misión recibir y dar salida a la carga química del aparato éste se carga por un cierre de puntero interior con tapón exterior (2).
Patent ES-253741-A1 (ES)
Title: Improvements relating to the polymerisation of butadiene
IPC: C08F36/06
Filed: 1959-11-26
Abstract: Butadiene is polymerized in the presence of soluble catalysts prepared by contacting a compound of a metal of Group VIII with an alkyl metal compound and ageing the catalyst mixture in predetermined amounts in an inert hydrocarbon solvent at below 50 DEG C. for 5 minutes to 2 hours and mixing the aged catalyst with all the butadiene before the polymerization reaction is started. Specified catalyst components are diethyl aluminium chloride, cobaltous chloride-pyridine complexes, and cobalt diacetyl acetonate while benzene is the specified solvent.
Patent ES-262136-A1 (ES)
Title: Process of drawing yarns of polymers based on acrylonitrile in hot vapors of organic liquids
IPC: D02J1/22
Filed: 1960-11-02
Abstract: Filamentary yarns and tows of polyacrylonitrile, free from contained solvent, are drawn in a medium comprising the vapour of n-amyl alcohol, isoamyl alcohol, or mixtures thereof, n-amyl acetate, isoamyl acetate, or mixtures thereof, or of cyclohexanone. The term "polyacrylonitrile" includes polymers, copolymers, grafted polymers and mixtures thereof containing 85-100% polyacrylonitrile and up to 15% of one or more copolymerizable ethylenic compounds. The vapour may be maintained at a temperature close to the boiling point of the liquid of which it is the vapour, usually slightly below the boiling point, so that drawing may be effected in the vapour of the boiling liquid. In Examples (1), (3), a polyacrylonitrile untwisted yarn is drawn up to 16,5x in cyclohexanone vapour at 153 DEG C., (2) a yarn of filaments of 85% polyacrylonitrile and 15% polyvinyl acetate twisted 50 turns per metre is drawn 11,4x in amyl alcohol vapour at 131 DEG C., (4) a tow of filaments of a copolymer of 92% acrylonitrile and 8% methyl methacrylate is drawn in saturated isoamyl acetate vapour at 145 DEG C. The process of the invention enables filaments to be drawn to a higher draw ratio than is possible by conventional methods, and for a given draw ratio the process yields filaments of higher tenacity.
Patent ES-265373-A1 (ES)
Title: 5- +-aminopropyl-5h-dibenz[b,f]azepine and the preparation thereof
IPC: C07D223/28
Filed: 1961-03-03
Abstract: The invention comprises 5-(g -aminopropyl)-iminodibenzyl, its acid-addition salts, and its preparation by reduction of 5-(b -cyanoethyl)-iminodibenzyl.
Patent ES-308634-A1 (ES)
Title: 17-acylates of 9alpha-fluoro-11beta, 17alpha-dihydroxy-16-methyl-1, 4-pregnadiene-3, 20-dione and corresponding-11-keto steroids and pharmaceutical compositions thereof
IPC: A61K41/00
Filed: 1965-01-27
Abstract: Novel steroids of the formula <FORM:1070751/C2/1> (wherein X is b -OH or keto and R is C1- 4 alkyl are prepared by acylation of the corresponding 17a -ols. The 11b -OH group may be oxidized to a keto group before or after acylation.ALSO:Anti-inflammatory steroids of the formula <FORM:1070751/A5-A6/1> (wherein X is b -OH or keto and R is C1-4 alkyl) are made up into pharmaceutical compositions for topical use with suitable carriers. The compositions may also contain preservatives, batceriostats and antimicrobial agents, particularly antibiotics.
Patent ES-311548-A1 (ES)
Title: Feeder device for fragile laminar articles
IPC: A21C15/00
Filed: 1965-04-07
Abstract: Wafer sheets 16 form a stack on a platform 14 of a magazine 10 and the section created by a suction head 20 is just insufficient to lift the uppermost wafer from the stack when an opening 22 (Fig. 1, not shown) in the head 20 is fully uncovered by a perforated section 32 in an endless web 24. This web comprises an integral number of pitches each of which is formed by a blank web section 30 and a larger perforated web section 32. A pitch of the web 24 is equal to the length of a wafer sheet. When a blank web section 30 passes across the suction head opening 22 the suction to which the uppermost wafer is exposed is cut-off. As the trailing edge of the blank web section 30 passes the edge 36 (Fig. 1, not shown) of the suction head 20 the increased suction lifts the uppermost wafer on to the suction web 24 and the wafer is carried past the suction head to be deposited on an endless conveyer 28. A lifting mechanism, which raises the platform an amount equal to a wafer thickness when a wafer is removed from the stack, is controlled by a detector 38. A magazine 12 is interchangeable with the magazine 10.
Patent ES-332043-A1 (ES)
Title: Surgical ligating disk having a noose forming ligature threaded therethrough
IPC: A61B17/12
Filed: 1966-10-07
Abstract: A device used to ligate a blood vessel comprises a disc-shaped member 1, through holes or slots in which is threaded a ligature 5, arranged to provide a noose 8 to be held tight about the blood vessel by a loop 7 of the ligature and by a enlarged or knotted end 6. In embodiments, the ligature is threaded through the disc-shaped member in various ways and, as illustrated in Figures 5 and 6 (not shown), the noose is held between the member and a bar (22) fitted in a groove in the member. The ligature is of catgut, cotton, silk, or nylon, and the member 1, which is about 1 or 2mm. in diameter, is of nylon, stainless steel, or of a gelatin absorbable in the body.. The surface of the member 1 may be roughened.
Patent ES-334627-A1 (ES)
Title: Pharmaceutical Compositions containing Proscillaridin A
IPC: A61K47/22
Filed: 1966-12-17
Abstract: Pharmaceutical compositions for the treatment of cardiac insufficiency comprise proscillaridin A and at least one sympathomimetic compound having positive inotropic cardiac action. The sympathomimetic compound may have the formula: in which R 1 and R 2 may be the same or different and represent hydrogen atoms, alkyl groups with 1-5 carbon atoms or hydroxyl groups, R 3 represents -H or -OH, R 4 represents -H or -CH 3 , and R 5 represents -H, an alkyl group with 1-5 carbon atoms, or an aralkyl group, the aryl moiety of which may if desired be substituted by one or more -OH, and the alkylene moiety of which contains 1 to 3 carbon atoms, which may be in the form of physiologically compatible acid addition salts thereof e.g. the hydrochloride, sulphate, tartrate, maleate, succinate, chlorotheophyllinate or methanesulphonate. Examples of sympathomimetics include noradrenalin, adrenalin, phenylepherine, paredrinol, nor-adrianol, p-hydroxy-ephedrine, metar aminol, isoproterenol, metaproterenol, effortil, synephrin 1-(4-hydroxy phenyl)-2-n-butylaminoethanol-1 and 1-(3, 5-dihydroxy phenyl)-2-[#-(p-hydroxyphenyl)-isopropylamino]-ethanol-1. T h e composition may also contain one or more water-soluble hydroxyalkyl-theophylline or theobromine derivative e.g. 7-#-hydroxy propyl-theobromine or theophylline or 7-(#-#- dihydroxypropyl)-theophylline. The compositions may be administered orally or parenterally in the form of dosage units containing conventional excipients, e.g. tablets, coated tablets, sustained release forms, ampoules, solutions and drops.
Patent ES-335611-A1 (ES)
Title: Water-soluble basic azo dyestuffs
IPC: C09B31/02
Filed: 1967-01-13
Abstract: The chlorides of 1-amino-4-, -5- and -8-[[alpha]- (N - trimethylamino) - acetyl] - naphthalene and 2 - amino - 6 - and - 8 - [[alpha] - (N - trimethylamino) - acetyl] - naphthalene are prepared by reacting a 1- or 2-acetylaminonaphthalene with aluminium chloride and chloracetyl chloride in presence of carbon disulphide, removing the carbon disulphide when evolution of HCl has ceased, decomposing the product with ice, reacting the filtered product with trimethylamine and finally hydrochloric acid. Equivalent amounts of dimethylamine, triethylamine, N-methylpiperidine or pyridine may be used.
Patent ES-337007-A1 (ES)
Title: Improvements in devices for modifying static electricity and its effects on the human body in automobile vehicles
IPC: H05F3/00
Filed: 1967-02-18
Abstract: A device suitable for treating travel sickness comprises a perforated case of electrically conductive material having means whereby it may be suspended on a wearer's body, the case containing at least one watersoluble salt. A metal chain may provide the means for suspension and the case, which may be of stainless steel, may comprise two parts secured together. The salt may comprise an exemplified mixture of salts and may be contained in a cotton bag within the case.
Patent ES-337531-A1 (ES)
Title: Apparatus for remotely indicating the level of liquid in a tank
IPC: G01F23/72
Filed: 1967-03-03
Abstract: The level of liquid in a sealed tank 2, Fig. 1, is indicated using a float 8 which comprises an annular magnet 9, housed in the float which is slidable along a non-magnetic steel tube 3, and an associated magnetic core 7 suspended on a stainless steel wire 5 from a disc 6. Between the disc and the core, the wire passes round a pulley 12 mounted on one end of a lever arm 13, the other end of which carries the core 16 of a differential transformer 17, which is thus positioned according to the wire tension. A counterweight 31 is arranged so that for a predetermined "equilibrium" tension, the core 16 is positioned centrally in the transformer 17. As the liquid level changes, the tension in the wire 5 and correspondingly the position of the core 16 will change accordingly due to the change in the Archimidean thrust on the float 8. A signal is thus transmitted from the transformer 17 to a two phase motor 21 which rotates the disc 6, via shaft 41, to re-position the float at the surface of the liquid. The amount of rotation of the shaft, indicating the change in liquid level, may be measured electrically, by mechanically connecting a three turn linear potentiometer (45), Fig. 2 (not shown), to the shaft 41, or pneumatically by controlling the pressure in a power relay 33 according to the rotation of the shaft. Alternatively a digital indication of the rotation of the shaft 41 may be obtained from a step-by-step motor (53), Fig. 3 (not shown), driven by pulses from the motor 21 and a photo-electric cell (56).
Patent ES-344464-A1 (ES)
Title: Improvements in or relating to zinc blast furnace
IPC: C22B19/18
Filed: 1967-08-25
Abstract: The zinc condensing efficiency in a zinc producing blast furnace unit which comprises a feed preparation machine, feed transfer apparatus, furnace charging gear, furnace shaft, gas offtakes and at least one condenser for zinc of the leadsplash type, is improved by introducing free or combined chlorine into the furnace unit. Combined chlorine may be used in the form of hydrogen chloride, ammonium chloride, or the chloride of a Group I or II element. The examples relate to (a) the introduction of chlorine gas into the offtake tube between shaft and condenser, and (b) the charging of sodium chloride briquettes to the shaft.
Patent ES-344717-A1 (ES)
Title: Pneumatic feeding arrangement for supplying fibrous materials
IPC: D01G23/08
Filed: 1967-09-02
Abstract: In a pneumatic feed system for delivering cotton fibres from a container 1 through a radial fan 7 and a branched pipeline 8 to feed shafts 9 associated with cards 10, the pressure increase produced when the cotton fibres in the shafts cover air outlets 12 actuates a device 14 to cut off the motor 4 driving feed rollers 2, 3. When one of the shafts has been emptied again by its delivery roller 11 sufficiently to allow air to escape at a sufficient rate from the outlet 12, the device 14 re-starts the motor 4. The motor 4 can alternatively be controlled by photo-electric cells 15 such that the motor is cut off when all the shafts are filled to the level of the cells.
Patent ES-344735-A1 (ES)
Title: Supercharged internal combustion piston engine
IPC: F02B37/10
Filed: 1967-09-04
Abstract: In an I. C. engine, having an exhaust gas turbine driven supercharger unit 2, Fig.1, additional power is supplied to the supercharger unit by an auxiliary drive comprising a hydraulic positive displacement motor 11 coupled to shaft 5 direct by and without transmission gearing. Operation: Oil is supplied from tank 18 via a transfer pump 20 and a high-pressure pump 16 to a hydraulic motor 11 and is returned to tank 18 via a pressure-maintaining valve 28 which prevents foaming or cavitation. At higher engine outputs when an auxiliary drive is not required the air pressure in a reservoir 8 acts via a signal line 25 on a servomotor 24 to fully or partially open valve 23 to by-pass the motor 11. If the oil flow through motor 11 is greater than the oil flow through pump 16 the motor 11 acts as a pump drawing oil via a line 30 through a relief valve 31. Alternatively pump 16 may be arranged to continuously supply oil to the motor 11. Pump 16 may be driven from the engine crankshaft or by a separate constant or variable speed motor. Valve 28 may be omitted and pump 16 may be the same construction as pump 11. Coupling 10 may be resilient or releasable during operation e.g. an over-running clutch, an electromagnetic coupling, a friction clutch or a hydraulic coupling. In an alternative arrangement the transfer pump is the engine lubricating pump (40), Fig. 2 (not shown) and lines 30 and 17 both lead to the pressure line (42) of the lubricating pump (40).
Patent ES-346914-A1 (ES)
Title: Leached amalgamated zinc anode
IPC: H01M4/42
Filed: 1967-11-08
Abstract: A porous electrode of amalgamated zinc is formed by (a) mixing NH 4 Cl powder, MgSO 4 powder and Zn powder, (b) adding an aliphatic organic liquid, (c) adding Hg 2 Cl 2 , (d) compacting the mixture while it sets, (e) leaching out all chloride ion and (f) drying the compact. In step (b) the liquid may be non-polar, inert and involatile, e.g. deodorized kerosine. In' step (e) the magnesium, ammonium and sulphate ions may also be leached out. The compact may be dried in a preheated oven after washing in MeOH. The dry electrode should be stored in a desiccator. An alkaline cell containing the electrode may be used at temperatures down to - 30 C. In the cell illustrated the depolarizer 12 may comprise HgO, MnO 2 or Ag 2 O and 5-25% of graphite.
Patent ES-347591-A1 (ES)
Title: Switch for electric toy and model railroad installations
IPC: A63H19/32
Filed: 1967-11-24
Abstract: A point, for a model railway or electric toy, has a base 1 with outer rails 2, 3 and inner rails 13, 14, each rail being connected to one of the underside contact plates 18, 15, 17, 16 respectively. A brass component comprising a frog 9, webs 5, 7 and point blades 4, 4' is rivetted to the point base 1 at 12, and a tenon 10' extends under the point base to attach the point blades 4, 4' to the point changeover mechanism (see Fig. 6) via a U- shaped member 34. The point changeover mechanism comprises a supporting plate 19 attached under the point base 1 by tenons 19', a point lever 21, 21', 22, 25 pivoted on a knife edge 20 and a sprung electrical contact bridge which is moved by the projection 25 of the point lever. The contact bridge has two sprung arms 29, 30 which can electrically connect contact plate 15 and plate 17 or plates 16 and 18, and also has a U-shaped member (which is attached to a bias spring 32) which abuts the tenon 10' thereby moving the point blades 4, 4'. The point may be operated by a solenoid.
Patent ES-356617-A1 (ES)
Title: Method and apparatus for induction heating of slabs
IPC: H05B6/02
Filed: 1968-07-29
Abstract: A multi-section cross-field induction coil 14 or 1411, for uniformly heating one or more elongated metal slabs 17 of differing widths, has means for separately applying voltage to each coil section, e.g. A, B, C, D, E, the voltage being substantially proportional to the number of turns in each section. The coaxial coil sections may have the same turns and dimensions, Fig. 4 (not shown), or comprise a large coil section B, a smaller bottom coil section A, and a plurality of smaller, upper coil sections C, D, E, for heating slabs 17c, 17d, 17e, of differing widths. The voltage for the end coil sections is increased slightly to compensate for heat losses. Coil sections may be independently energized or deenergized to allow for loads of differing widths being heated. The coil 14 is vertically disposed, and slab 17 is raised into position for heating by a support beam 50. Coil 14 is water-cooled via inlet 18 and outlet 19, and has shields 28, 29, to reduce heat losses from the top of the coil. By means of autotransformers 34-37 the voltage in coil sections A, C, D and E can be varied. Power factor control capacitances 32 are connected in parallel across each coil section. Specifications 1,207,522 and 1,227,003 are referred to.
Patent ES-357126-A1 (ES)
Title: Production of propylene polymers
IPC: C08F10/06
Filed: 1968-08-10
Abstract: Propylene is polymerized in the gaseous phase in the presence of a Ziegler catalyst system wherein purified propylene (which is suitable for achieving a catalyst activity of at least 3000 parts of polymer per part of catalyst per hour a method of determining the catalyst activity is given in the Specification) is introduced in liquid form into the reaction zone, vaporized and polymerized therein, in the presence of a catalyst whose molar ratio of titanium compound to aluminium compound is in the range of 1: 0À5 to 1: 6. Unpolymerized monomer, on leaving the reaction zone, may be condensed and recycled with fresh monomer. Preferably the reaction is carried out at 10 to 100 atmospheres, 70 to 120 C., and using a catalyst comprising TiCl 3 , AlCl 3 and Al(Et) 3 . The homopolymerization of propylene is exemplified and the process is also applicable to the copolymerization of ethylene and propylene.