baber/WOPTO huggingface dataset:
Patent SG-11201908055W-A (SG)
Title: Methods for determining potency of adeno-associated virus preparations
Inventor: BENDIK MARIAN
IPC: G01N33/569
Filed: 2018-03-02
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 07 September 2018 (07.09.2018) WIP0 I PCT o °nolo momioolioimo in oimIE (10) International Publication Number WO 2018/160975 Al (51) International Patent Classification: GO1N 33/569 (2006.01) GO1N 33/48 (2006.01) C12N 15/864 (2006.01) (21) International Application Number: PCT/US2018/020676 (22) International Filing Date: 02 March 2018 (02.03.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/467,045 03 March 2017 (03.03.2017) US (71) Applicants: BAXALTA INCORPORATED [US/US]; 1200 Lakeside Drive, Bannockburn, IL 60015 (US). BAX- ALTA GMBH [CH/CH]; Zaehlerweg 4, 6300 Zug (CH). (72) Inventors: BENDIK, Marian; Gabcikova 4, 84105 Bratislava (SK). NECINA, Roman; Mengergasse 44/2, 1210 Vienna (AT). BOEHM, Ernst; Muehlweg 94, 1210 Vienna (AT). GRANINGER, Michael; Gernotgasse 3/11, 1150 Vienna (AT). FIEDLER, Christian; Raaberbahn- gasse 18/36, 1100 Vienna (AT). (74) Agent: SULLIVAN, Nicole R.; Troutman Sanders LLP, 875 Third Avenue, New York, NY 10022 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. = (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) O 1-1 (54) Title: METHODS FOR DETERMINING POTENCY OF ADENO-ASSOCIATED VIRUS PREPARATIONS (57) : Provided herein are methods of measuring the qualitative and/ or quantity attributes of gene therapy vector preparations. O In certain embodiments, the gene therapy vector preparations are Adeno-associated virus (AAV) preparations (e.g., AAV8). In certain \" embodiments the methods comprise determining the potency or dose of the AAV preparation using ELISA, or ELISA in combination 0 with cryogenic transmission electron microscopy (CryoTEM).
Patent IS-2861-B (IS)
Inventor: HAGENAH GERHARD
IPC: E01C5/06
Filed: 2004-03-23
Abstract: An essentially quadrate paving stone having a corresponding base block (21) is provided on all four side surfaces (25, 26) with flange-like, upright spacers (22) which are spaced apart from each other at intervals corresponding approximately to the width of the spacers, making it possible for them to make an interlocking connection with adjacent shaped paving stones of the same type. Furthermore, the bottom side (24) of the paving stone features a number of transverse, gutter-like depressions resulting in the formation of ribs between these depressions. This creates an additional dentification, or anchoring, in the bed surface of the installed paving stones.
Patent IS-2754-B (IS)
Inventor: DIFFERDING EDMOND
IPC: A61P21/00
Filed: 2005-06-29
Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of general formula (B. geometrical isomers, enantiomers, diastereoisomers, mixtures of each of these and pharmaceutically acceptable salts thereof. whereinR<sup>1</sup> is methyl,R<sup>2</sup> and R<sup>4</sup> are hydrogen.R<sup>3</sup> is alkyl or haloalkenyl, andX is -COOH. -COOMe or -COOEt.
Patent AT-403561-B (AT)
Inventor: PESCHEL WOLFGANG DIPL ING
IPC: B60C11/11
Filed: 1995-01-25
Granted: 1998-03-25
Abstract: A vehicle tyre, esp. for winter use, has a tread profile with circumferential and lateral channels forming, on each side of the tyre equator (M-M), a row of shoulder blocks (1) and a pair of central block rows (2, 3), with all blocks having fine lamellae cuts. Both the adjacent blocks (3a) of the circumferential row (3) nearer the tyre equator (M-M) and also the blocks (2a, 3a) of the adjacent block rows (2, 3) are separated by channels with combined broad and narrow sections (6a, 6b, 7a, 7b). Narrow channel sections (6b, 7b) are shallower than the broad channel sections (6a, 7b).
Patent AT-405171-B (AT)
Title: Method for the at least partial evacuation of air from a liquefied gas tank and a compressed-air air pump based on a venturi tube for use in such a method
IPC: B67D7/06
Filed: 1996-02-02
Granted: 1999-06-25
Abstract: The invention relates to a method for the at least partial evacuation of air from a liquefied gas tank. It is characterized in that a compressed-air air pump based on the venturi tube is used for the suction of air. In one embodiment, provision is made for preferably approximately 10 kg of liquefied gas/m2 tank contents to be added after evacuation of the tank. The invention also relates to a device for carrying out the method. <IMAGE>
Patent AT-404051-B (AT)
Title: Retaining arrangement for a shuttering panel of end shuttering for floors or ceilings
IPC: E04G11/00
Filed: 1997-05-07
Granted: 1998-08-25
Abstract: A retaining arrangement 1 for a shuttering panel 2 of end shuttering for floors or ceilings has an upright which can be braced on the floor-bearing or ceiling-bearing masonrywork M via an anchor rod 11 and is supported beneath the anchor rod 11 by means of a spacer and above the anchor rod, with the interposition of the shuttering panel 2, on the outside of the masonry work. In order to achieve a retaining arrangement which can be handled easily and is nevertheless stable, the invention provides an anchor cross 3 with one longitudinal bar and two transverse bars 4, 5, 6, the longitudinal bar 4 forming the upright, the bottom transverse bar 5 forming the spacer and the top transverse bar 6 forming a panel support, the top and bottom transverse bars 5, 6 are arranged adjustably on the longitudinal bar 4, the longitudinal bar 4 has a threaded rod, which can be fitted through a bore in the masonry work, with tensioning nuts 12 on both sides as the anchor rod 11, and a sleeve 13 with a bearing web 14 which grips beneath the shuttering panel 2 is fitted, such that it can be adjusted with sliding action, on the longitudinal bar 4 between the anchor rod 11 and top transverse bar 6. <IMAGE>
Patent AT-406857-B (AT)
Inventor: BERLIZ GERHARD DIPL ING
IPC: B61L1/20
Filed: 1998-05-20
Granted: 2000-10-25
Abstract: The signaling system has track circuit measurement devices, axle meters etc. and an evaluation circuit via which the system is connected to a voltage supply and which evaluates signal voltages from the signaling system. A separate monitoring device receives signaling system operating parameters, e.g. the supply and signal voltages and if appropriate the phase of the voltage measurement value in the rest state independently of the track-free measurement system. The operating parameters are measured and evaluated against time.
Patent HU-188771-B (HU)
Inventor: BERG HANS
IPC: F01P3/18
Filed: 1982-02-02
Abstract: Anwendungsgebiete der Erfindung sind wassergekuehlte Brennkraftmaschinen mit Abgasturboaufladung und Ladeluftkuehlung der Bauart Luft-Wasser. Ziel ist die Verbesserung des Kuehleffektes. Aufgabe ist es, durch eine wirksame Zwischenkuehlung der Ladeluft bei geringstem zusaetzlichem Bauaufwand eine Leistungssteigerung herbeizufuehren. Die Aufgabe wird geloest, indem das Kuehlwasser nach Durchstroemen des Hauptkuehlers und der Wasserpumpe abgezweigt und ueber einen Wasserkuehler als Nebenkuehler auf naeherungsweise Umgebungstemperatur abgesenkt und ueber den Kuehlwasserraum oder der Saugseite der Wasserpumpe zugefuehrt wird. Die Anordnung des Nebenkuehlers erfolgt vorzugsweise parallel zum Hauptkuehler vor diesem in Stroemungsrichtung der Kuehlluft. Einsatzgebiete sind selbstfahrende Landmaschinen, Fahrzeugmotore.
Patent HU-184245-B (HU)
Inventor: POLONSYKY GYOERGY
IPC: B01F13/00
Filed: 1980-03-07
Abstract: A találmány tárgya sziláid műtrágyakeverő gép többkomponensű szilárd műtrágyaféleségek tetszés szerinti keverési arányú előállításához, amelynek komponensenként tartálya, és ez alatt szállítóberendezése, valamint az utóbbiak alatt gyűjtő szállítóberendezése van. A találmány szerinti műtrágyakeverő gép lényege, hogy bolygatóművel ellátott keverőtartályai és ezek alatt változtatható sebességű szállítócsigái vannak, amelyek meghajtására hajtóműves variátorok szolgálnak. A szállítócsigák ürítő nyílásai alatt gyűjtő szállítószalag helyezkedik el, amely felett több sorban és soronként eltolva keverőekék vannak, amelyek beállíthatók.  1. óbro -1-
Patent IT-1235374-B (IT)
Title: N-phosphono:methyl glycine prepn.
Inventor: GRAZIELLO DONADELLO
IPC: A01N/
Filed: 1989-06-15
Granted: 1992-06-30
Abstract: A new method for the prepn. of n-phosphonomethyl glycine by the phosphonomethylation of glycine in an aq.-alcoholic soln., characterised in that it comprises: i) reacting glycine with an aq.-alcoholic soln. of HCHO in the presence of a base selected from the gp. consisting of alkali and alkaline earth hydroxides; ii) reacting the soln. thus obtd. with trialkylphosphite and; iii) effecting hydrolysis in an aq. medium and recovering the N-phosphonomethyl glycine by crystallisation.
Patent LT-4840-B (LT)
Title: A measuring method of direct-axis synchronous inductive reactance of a synchronous machine
Inventor: GECYS STEPONAS
IPC: G01R31/34
Filed: 1999-10-05
Abstract: Invention belongs to the field of electromechanical devices and may be used in the production and operation of the synchronous machines for determining their electromagnetic parameters. Mode for determining the inductive longitudinal resistance of the synchronous machines is new for it determines the mean of the resistance by the proportion of the voltages and respective currents. For measurement inductive longitudinal resistance it is needed to measure the voltage of the phase U, current I, electromotive power E, angle of the power factor φ angle among the current and the electromotive power ψ and the active resistance R as the curls temperatures function. Longitudinal resistance X(d) is calculated by the formula:<IMAGE>The dependency of the inductive synchronous longitudinal resistance from the machine's magnetisation is calculated by changing the mean of electromotive power E.
Patent ZA-87591-B (ZA)
Title: Novel derivatives of eryhromycylamine
Inventor: BONJOUKLIAN ROSANNE
IPC: A47C17/66
Filed: 1987-01-27
Abstract: New 9-N-substituted derivatives of erythromycylamine, having the nucleus <CHEM> with superior oral activity against Gram-positive pathogens, are provided.
Patent AT-397539-B (AT)
Title: Window or door
IPC: E06B3/58
Filed: 1992-10-01
Granted: 1994-04-25
Abstract: The invention relates to a window or a door having glass panes 2, in particular insulating glass panes, which are inserted into a wooden frame 1, butt on one side against extensions 3 of the frame 1 and are retained via glazing bars 4, 5 on the opposite side, said glazing bars being inserted, by means of protrusions 7, in grooves 6 arranged on the frame 1, and, in said window or door, the grooves 6 and protrusions 7 run obliquely outwards, with the result that the glazing bars 4, 5 are forced against the frame by retaining means which are pressed in from the side of the panes 2. In order to allow straightforward insertion of the last glazing bar, the ends of a glazing bar 4, which butt against two glazing bars 5 which adjoin at right angles and are provided with a mitre cut 11, are recessed on their surfaces 12, 13 which butt against the frame 1 and the glazing bar 2, said recessing beginning from the air- side tip 16, butting against the adjoining glazing bar 5, and extending to a depth which corresponds to the width B of the adjoining glazing bar 5. <IMAGE>
Patent AT-391770-B (AT)
Title: Electrical multilayer component having a sintered, monolithic ceramic body, and a method for producing the electrical multilayer component
Inventor: UNTERLASS JOSEF DIPL ING
IPC: H01G4/30
Filed: 1987-07-31
Granted: 1990-11-26
Abstract: The sintered monolithic ceramic body 1 of the electrical multilayer component has cavities 2, 3 which are open alternately on opposite end faces 4, 5 and to a minor extent 15, 16 towards the side faces 6, 7; the cavities 2, 3 contain ceramic particles 8 as supporting elements and are completely filled with pressed-in metal, whose melting temperature is considerably lower than the sintering temperature of the ceramic body 1 and preferably, in the liquid state, wets the surfaces of the ceramic layers 9, 10 in the cavities 2, 3; all the edges 17, 18, 20 between the six outer faces 4, 5, 6, 7, 19 are rounded, so that the metal coatings 11, 12 extend as far as the contact layers 13, 14 which are applied after the metal has been pressed in. <IMAGE>
Patent AT-388907-B (AT)
Title: Process and device for final clarification of a gas- saturated liquid
Inventor: MUELLNER JOHANNES DIPL ING DR
IPC: C02F1/20
Filed: 1984-06-27
Granted: 1989-09-25
Abstract: In a biological anaerobic or aerobic process, between the gas introduction in the reactor 1 and the final clarification in the final clarification tank 2, the liquid to be clarified is degassed under reduced pressure 3. This has the effect that in the final clarification tank 2 the liquid is not saturated in gas and therefore does not degas, so that the clarifying function (sedimentation) proceeds independently of gas bubble ascension, that is to say more rapidly, and the separation and removal of the two products is performed before reaching saturation due to the bacterial metabolic products. The inventive device is characterized by a reduced pressure degassing device 3 which is disposed between the reactor 1 having a gas introduction device 17 and the final clarification tank 2. The reduced pressure degassing device 3 is preferably spatially higher than the reactor 1 and the final clarification tank and is connected to a hydraulic compression device 4 for the separated gas. <IMAGE>
Patent AT-388242-B (AT)
Title: Trigger apparatus for automatic handheld firearms, with hammer-action firing
Inventor: STOCKINGER EDUARD
IPC: F41A19/02
Filed: 1984-12-05
Granted: 1989-05-26
Abstract: A trigger apparatus for automatic handheld firearms with hammer-action firing has a hammer 3 which is cocked during the rearward movement of the breech, a locking lever 5 which is controlled by the breech, and an initiating slide 7. The initiating slide 7 can be operated by the trigger against spring force. An interrupter 9 is mounted in the initiating slide 7 and acts only over about half the slide movement as a catch lever for the hammer 3. In order in the case of a trigger apparatus such as this to positively limit the number of shots when the trigger is in the continuous firing position, using relatively simple means, a shot number limiter is provided. This shot number limiter comprises a disc 10 which is mounted in the initiating slide 7 and has latching recesses 10a-10c, and has locking teeth 10d for a sprung locking catch 11. The disc 10 is rotated into the latching recesses 10a-10c by means of successive hammer action when the initiating slide 7 is in the rear position with respect to the barrel direction, with the last latching recess 10c in the rotation direction being in the form of a catch for the cocked hammer 3, however. <IMAGE>
Patent CH-621454-B (CH)
Inventor: ERARD RAOUL-HENRI
IPC: G01C17/04
Filed: 1978-03-03
Abstract: The watch carries a fixed, symbolic image (2.1) of Mecca, which can be seen when it is oriented, over an arc of a great circle, towards Mecca, whilst it is more or less obscured when it is oriented in another direction. The watch has a system composed of two polarised filters, one (8) oriented manually as a function of the location, and the other (9) magnetically by the terrestial magnetic field. <IMAGE>
Patent DK-166022-B (DK)
Inventor: DEVLIN JOHN P
IPC: C07D295/108
Filed: 1984-03-20
Abstract: 1. Bis-(piperazinyl- or homopiperazinyl) alkanes of the general formula I  see diagramm : EP0122488,P21,F1  wherein R1 , R2 , R3 and R4 which may be identical to or different from each other, are each hydrogen, alkyl having 1 to 4 carbon atoms, hydroxyl, alkoxy having 1 to 4 carbon atoms, alkanoyloxy having up to 4 carbon atoms, halogen, trihalomethyl, di-C1-4 alkylamino, C1-4 alkoxycarbonyl, nitro, cyano or acyl having 1 to 3 carbon atoms ; R5 and R6 , which may be identical to or different from each other, are each hydrogen, methyl, hydroxyl, carboxyl, C1-4 alkoxycarbonyl, hydroxymethyl, phenyl or p-chlorophenyl, R7 and R8 are each hydrogen or methyl ; j and k are integers from 0 to 3, their sum being no more than 4 ; m and n are integers from 0 to 3, their sum being no more than 4 ; A is -CH2 - or -CH2 CH2 - ; or R5 and R7 together or R6 and R8 together are oxo, provided k or m is other than O ; or R5 and R7 together and R6 and R8 together are oxo, provided k or m are other than O ; R9 and R10 , which may be the same or different, represent hydrogen or from one to four methyl substituents on the carbon atoms of the piperazine ring (A = -CH2 -) ; R11 , R12 , R13 and R14 , which may be identical to or different from each other, are each hydrogen or methyl ; or R11 and R12 together and/or R13 and R14 together are oxo ; and X is alkylene of 1 to 2 carbon atoms, optionally hydroxy-substituted with the proviso that when A = -CH2 -, R1 to R14 are hydrogen and j, k, m and n are each zero, then X cannot be 1,2-ethylenediol, and physiologically acceptable acid addition salts thereof.
Patent DK-148334-B (DK)
Inventor: HANSON STEEN
IPC: G01P5/26
Filed: 1982-04-07
Abstract: In a method of measuring velocity gradients in a sample volume (2) in a flowing medium, by which method radiation scattered by particles entrained by the medium and irradiated by spatially coherent electromagnetic radiation, in particular laser light, is detected and measured and the difference in Doppler shift in the radiation from different particles in the sample volume (2) used as a measure of the velocity gradient, an optical element (3) is inserted in the radiation path from particles in the sample volume (2) to the detector (4). The optical element (3) has such properties that essentially only radiation scattered simultaneously from particle pairs in the sample volume (2) spaced apart a distance determined by the optical element (3) are made part of the measuring signals to be combined to form the signal which is a measure of the difference in the Doppler shifts and thereby of the velocity gradient in the sample volume (2) defined by the measurement points. The optical element (3) may for example be an optical grating of the absorption, phase or reflection type or intermediate forms, a birefringent element, a Bragg cell, a combination of a totally reflective surface and a beam splitter or possibly a glass plate having one of its surfaces coated with a totally reflective material. The apparatus comprises a source for electromagnetic radiation (1), a detector (4) for receiving radiation scattered from particles in a sample volume (2), means for recording the output signals from the detector (4) and an optical element (3) of the above-mentioned type defining the position of a relevant particle pair.
Patent DK-159701-B (DK)
Inventor: FURUTSU AKIRA
IPC: H02G1/00
Filed: 1984-03-30
Abstract: Disclosed is a machine for automatically banding particularly linear objects in groups with strap-type banding elements having interlockable male and female members at one and the other ends thereof respectively, which comprises a pistol-shaped machine body and an operation lever provided to a grip handle thereof and with which, when the operation lever is triggered, each banding element loaded on the machine body is fed forwardly in the machine body, applied about a group of objects to be banded and received on a front end portion of the machine body and then fastened with its male and female members interlocked to accomplish banding, the machine being characterized by comprising a pusher member driven through triggering of the operation lever to move in a guide path in the machine body from a rear end portion to a front end portion of the machine body while pushing a banding element, a stopper for fixing an end portion of the banding element at a front end portion in the guide groove during a banding operation, and a pusher lever pivotally supported at a front end portion of the pusher member and having a bending face along its front edge which is adapted to bring to be interlocked the male and the female members of the banding element after the movement of the element is stopped by the stopper.
Patent DK-160297-B (DK)
Inventor: HUBELE ADOLF
IPC: A01N37/44
Filed: 1981-07-24
Abstract: The invention relates to novel microbicides of the general formula I <IMAGE>   wherein R is hydrogen or methyl, Ar is a phenyl or  alpha -naphthyl group which is substituted by NH2 or NO2 and further radicals, W is a cyano, ester, alkenyl or alkynyl group, and B is alkyl, alkenyl, cyclopropyl, 2-furyl, 2-tetrahydrofuryl,  beta -(alkoxy)ethyl, triazolylmethyl, methylsulfonylmethyl, alkoxymethyl, alkenyloxymethyl, alkynylmethyl, alkylthiomethyl, alkenylthiomethyl, alkynylthiomethyl, -OSO2-alkyl, -OSO2NH(alkyl) or -N(alkyl)2. The invention also describes plant protection compositions which contain these compounds, a process for the production of the novel compounds and compositions, and a method of controlling phytopathogenic microorganisms which comprises the use thereof.
Patent FI-44564-B (FI)
Inventor: HUKKI R
IPC: B03D1/04
Filed: 1966-06-13
Granted: 1971-08-31
Abstract: 1,058,914. Froth flotation. OUTOKUMPU OY. June 14, 1965, No. 25097/65. Heading B2H. Froth flotation apparatus operating under a common head of vacuum comprises a pre-conditioning and aerating unit 1, into which pulp and gas are introduced via pipes 3, 4, the pulp being fed via a pipe 6 into a flotation chamber 8. Additional gas is introduced via a pipe 13. Froth is collected by a section 10 and directed into a bubble column 19. Preconditioned particles, treated with reagents to be floatable proceed upwards, and unwanted particles downwards, the downward movement being assisted by wash solutions introduced at 21. Final concentrate is drawn into a cyclone 23 for separation of solids and liquids, and concentrate pulp is discharged into a vessel 25 and over a weir 16, vessel 17 and weir 18. Gas separated in the cyclone is directed via a conduit 27 to a vacuum pump. In a further embodiment, five flotation chambers are employed operating under a common head of vacuum. Pulp material is drawn into rough flotation units (28, 29 Fig. 2) and the rough concentrates rise in columns (37, 38) and are combined in a chamber (30), separation of gas being effected in cyclones (41, 42.) Tailing pulp from the chamber (30) is returned to the chamber (28). Further flotation scavenger chambers (31, 32) receive the rougher tailings for further separation and the coarsest tailings are discharged at (53, 54).