baber/WOPTO huggingface dataset:
Patent PT-2004183-E (PT)
Title: Mazindol combination in the treatment of attention deficit/hyperactivity
Inventor: KONOFAL ERIC
IPC: A61K45/06
Filed: 2007-04-11
Abstract: Use of mazindol (I) for the preparation of a drug for the preventive and/or curative treatment of the attention deficit hyperactivity disorder (ADHD) or at least one of these symptoms in a patient. An independent claim is included for a composition comprising (I) and excipients for the preventive and/or curative treatment of ADHD or any of its symptoms. ACTIVITY : Nootropic; Tranquilizer; Hypnotic; Muscular-Gen; Neuroprotective; Antiparkinsonian; Metabolic. MECHANISM OF ACTION : Dopamine inhibitor; Noradrenalin reuptake inhibitor. No biological data given.
Patent PT-2135414-E (PT)
Title: Method for optimizing a minimal-phase transmission characteristic and associated transmission system
Inventor: DETERT THORBEN
IPC: H03H17/02
Filed: 2008-03-28
Abstract: The invention relates to a method for optimizing a transmission segment having a minimal-phase transmission characteristic (9; 9') from a transmission segment having a non-minimal-phase transmission characteristic (8) upstream of an equalizer (7), generating the transmission segment having a minimal-phase transmission characteristic (9; 9') from the transmission segment having a non-minimal-phase transmission characteristic (8) and a prefilter (6;6<SUP>(1)</SUP>, 6<SUP>(2)</SUP>,..., 6<SUP>(n)</SUP> ). In order to determine the transmission characteristic (H
Patent PT-2130554-E (PT)
Title: Albumin-free factor viii formulations
Inventor: BJORNSON ERIK
IPC: A61K38/43
Filed: 2000-02-22
Abstract: A Factor VIII composition formulated without albumin, comprising the following formulation excipients in addition to Factor VIII: 4% to 10% of a bulking agent selected from the group consisting of mannitol, glycine and alanine; 1% to 4% of a stabilizing agent selected from the group consisting of sucrose, trehalose, raffinose, and arginine; 1 mM to 5 mM calcium salt; 100 mM to 300 mM NaCl; and a buffering agent for maintaining a pH of approximately between 6 and 8. Alternatively, the formulation can comprise 2% to 6% hydroxyethyl starch; 1% to 4% of a stabilizing agent selected from the group consisting of sucrose, trehalose, raffinose, and arginine; 1 mM to 5 mM calcium salt; 100 mM to 300 mM NaCl; and a buffering agent for maintaining a pH of approximately between 6 and 8. In a further embodiment, the formulation can comprise: 300 mM to 500 mM NaCl; 1% to 4% of a stabilizing agent selected from the group consisting of sucrose, trehalose, raffinose, and arginine; 1 mM to 5 mM calcium salt; and a buffering agent.
Patent PT-2085188-E (PT)
Title: Spreading pliers
Inventor: BATTENFELD KURT
IPC: B25B7/04
Filed: 2009-01-27
Abstract: The pliers (1) have a transmitting mechanism for transmitting actuating force of a user applied at hand levers (2, 3) to actuating forces at expanding jaws (4, 5). Another transmitting mechanism is interconnected between the jaws and expanding elements (8, 9) for converting a pivoting movement of the jaws into a translatory movement of the expanding elements in a direction of an expanding axis (43) or a parallel movement of the expanding elements. The expanding elements are movably guided together by direct support in the direction of the axis and are rotatably supported around the axis.
Patent PT-561639-E (PT)
Inventor: TURNER WILLIAM WILSON JR
IPC: C07K7/06
Filed: 1993-03-18
Abstract: Provided are compounds of the formula (1): <CHEM>  wherein R' is hydrogen, methyl or NH2C(O)CH2-;     R'' is methyl or hydrogen;     R is hydroxy or hydrogen;     R1 is hydroxy, hydrogen, or hydroxysulfonyloxy;     R7 is hydroxy, hydrogen, hydroxysulfonyloxy or phosphonooxy; R2 is a novel acyl side chain. Also provided are novel formulations, methods of inhibiting fungal and parasitic activity, and a process for preparing dideoxy (R=H) forms of the compounds.
Patent PT-755524-E (PT)
Inventor: LION DIDIER
IPC: G01S13/93
Filed: 1995-04-11
Abstract: PCT No. PCT/FR95/00464 Sec. 371 Date Oct. 15, 1996 Sec. 102(e) Date Oct. 15, 1996 PCT Filed Apr. 11, 1995 PCT Pub. No. WO95/28653 PCT Pub. Date Oct. 26, 1995A process for monitoring traffic for automatic vehicle incident detection using radar waves to detect the vehicles, their instantaneous speed and their distance. The process consists in correlating the information obtained regarding vehicles in one and the same distance bracket during two consecutive processing time intervals, so as to determine, at each instant, the acceleration of each vehicle and a prediction of its speed, and in then detecting an incident in a distance bracket by detecting the passing of the speed of a vehicle below a given speed threshold. The advantages of the process resides in rapid incident detection in regard to a road or motorway network, with a view to informing the users rapidly.
Patent PT-800578-E (PT)
Inventor: CHATTERJEE MALAYA
IPC: A61K39/12
Filed: 1995-12-28
Abstract: The present invention provides a monoclonal anti-idiotype antibody 3H1 that escapes immune tolerance and elicits a specific immune response to CEA in mice, rabbits, monkeys, and patients with advanced CEA-associated disease. This invention also provides compositions which can be used in the detection or treatment of CEA-associated tumors mimics a specific epitope on carcinoembryonic antigen and a hybridoma that produces 3H1.
Patent PT-831938-E (PT)
Title: Radiolabeled peptide compositions for site-specific targeting
Inventor: SRINIVASAN ANANTHACHARI
IPC: A61K103/10
Filed: 1996-06-06
Abstract: This invention relates to radiolabeled peptide compositions for radiopharmaceutical use and, more specifically, to radiolabeled peptides for diagnostic or therapeutic use having an unmodified carboxy terminal amino acid. The radiopharmaceutical composition may be used for targeting a selected biological site. The radiolabeled peptide is characterized by having its carboxy terminal amino acid in its carboxylic acid form and the peptide is coupled to a diagnostic or therapeutic radionuclide by a chelating agent. The radiopharmaceutical composition preferably comprises a radiolabeled peptide selected from the group consisting of somatostatin, an analog of somatostatin, a derivative of somatostatin and peptides capable of binding to the somatostatin receptor, where the peptide is coupled to a diagnostic or therapeutic radionuclide by a chelating agent has its carboxy terminal amino acid in its carboxylic acid form.
Patent PT-926970-E (PT)
Inventor: DEGEN HUGO
IPC: A47C23/02
Filed: 1996-09-17
Abstract: The main bridge (6) supporting the load has one or more supporting members (8) more flexible or elastic than it. These members are flat, and protrude from the bridge in the sideways direction, parts of them extending upwards beyond the bridge surface. The members can bend downwards under load, the area nearest the bridge bending at the most through no greater an angle than one further away. Each member can form a wing-type lip sloping upwards. Alternatively, it can be divided into several segments. There can be a flat horizontal supporting member along its outer edge.
Patent PT-871754-E (PT)
Title: Method for obtaining retroviral packaging cell lines producing high transducing efficiency retroviral supernatant
Inventor: RIGG RICHARD J
IPC: C12N7/00
Filed: 1996-12-13
Abstract: PCT No. PCT/US96/20777 Sec. 371 Date Apr. 15, 1997 Sec. 102(e) Date Apr. 15, 1997 PCT Filed Dec. 13, 1996 PCT Pub. No. WO97/21825 PCT Pub. Date Jun. 19, 1997This invention provides a method for obtaining a recombinant retroviral packaging cell capable of producing retroviral vectors as well as the recombinant packaging cell obtained by the method. Also provided is a method of producing recombinant retroviral particles obtained by introducing into the packaging cells obtained according to the methods disclosed herein, a recombinant retroviral vector and propagating the resulting producer cells under conditions favorable for the production and secretion of retroviral vector supernatant. The retroviral supernatant produced by these methods also is claimed herein. This invention further provides a method for screening retroviral vector supernatant for high transduction efficiency and methods for producing retroviral vector supernatant for transducing cells with high efficiency in gene therapy applications.
Patent PT-864223-E (PT)
Inventor: BOHM MARKUS
IPC: H04N3/15
Filed: 1997-09-27
Abstract: To avoid the overexposure and underexposure of pixels which occurs with high image contrasts, each pixel contains a local autoadaptive control. With the help of this control, each pixel automatically ends its integration period as soon as it has integrated enough photoelectric current. An analog signal represents the length of the integration period selected by the pixel. Together with the integrated pixel signal, it represents brightness information with high dynamics and with low requirements regarding the dynamics of the individual signals. Because of their local adaptivity, the image sensors are suitable for all applications where high brightness contrasts must be processed, such as guiding a motor vehicle in highway traffic, nature films and astronomy.
Patent PT-952797-E (PT)
Inventor: PHILOT GEORGE GUARANY
IPC: A61F5/01
Filed: 1997-07-18
Abstract: A combined, reconfigurable, multi-purpose external orthopedic fixation device and multi-functional prosthesis, for use alternatively as an external orthopedic fixation device for providing support and/or traction for a sprained, fractured, or broken limb of a warm-blooded animal, especially a human being, and as an artificial prosthesis for providing both substitute elementary limb functionality and substitute multi-purpose specific task functionality of a limb, especially an upper limb, such as a finger, hand, wrist, forearm, or elbow, of a warm-blooded animal, especially a human being, is disclosed. The apparatus includes at least one flexible tubular elongate member having a flexible strengthening rod therein, and a pair of end caps. Other embodiments of the apparatus further include one or a plurality of one or more additional elements including a cushioning support that is slidable along the elongate member; a stop for fixing the position of a cushioning support; a uni-dimensional joint for connecting ends of one or more elongate members together in a two-dimensional configuration; a two-dimensional joint for connecting ends of two or more elongate members together in a three-dimensional configuration; a panel of webbing material for supporting a limb; a rigid support member generally contoured to and for supporting a specific limb; and a variety of implements for performing certain useful functions, such as personal hygiene and grooming, eating, writing, and simple chores, that can be attached to one or more ends of an elongate member in place of the end caps.
Patent PT-1035834-E (PT)
Inventor: EDGREN DAVID E
IPC: A61K9/00
Filed: 1998-11-23
Abstract: A dosage form comprising a composition comprising a drug surrounded by a first coat and a second coat with an exit for administering the drug to a patient; and a method of using the dosage form are disclosed for an indicated therapy.
Patent PT-939231-E (PT)
Inventor: ARBEUS ULF
IPC: F04D3/00
Filed: 1999-02-01
Abstract: The invention concerns a seal device for a submersible machine, such as a pump or a mixer. The seal device is designed as an easily replaceable unit comprising two mechanical face seals (4,6) and (5,7) resp, parted by a room for a barrier liquid in which a pump impeller (10) is located, said impeller circulating the barrier liquid passing it along the seals and through cooling channels in the driving unit of the machine. <IMAGE>
Patent PT-1059915-E (PT)
Inventor: VINCENT LENAERTS
IPC: A61K47/36
Filed: 1999-02-24
Abstract: The present invention is concerned with a solid slow release oral pharmaceutical dosage unit resistant to amylase which comprises a solid dosage unit made up of an admixture of a therapeutic dosage of an orally effective pharmaceutical product, an optional polysaccharide or polyol, and cross-linked high amylose starch, wherein the cross-linking of the high amylose starch has been carried out with a covalent or non-covalent cross-linking agent with from about 0.1 g to about 30 g of cross-linking agent per 100 g of high amylose starch.
Patent PT-1162414-E (PT)
Inventor: JIROU FUKUDOME
IPC: F25B40/02
Filed: 1999-08-09
Abstract: A refrigerant supercooling circuit comprising a receiver (5) for retention of a liquid-phase refrigerant installed in a refrigerant line (23) connecting a first expansion valve (45) and a plurality of second expansion valves (71), an extraction line (61) for taking out the liquid-phase refrigerant in the receiver (5), a third expansion valve (62) in the extraction line, the portion of the extraction line (61) downstream of the third expansion valve (62) being passed through the receiver (5) or through a supercooling tank (63), the arrangement being such that the degree of opening of the first expansion valve (45) is controlled either according to the refrigerant pressure (P1) on a refrigerant line (21) connecting the delivery side of a compressor (2) and a four-way valve (3), or according to the degree of supercooling (SC) in the outlet of an outdoor heat exchanger (4), or according to the pressure difference across the first expansion valve (45). <IMAGE>
Patent PT-1123029-E (PT)
Inventor: IACCHETTI GIULIO
IPC: A47J37/10
Filed: 1999-10-05
Abstract: A untensil (10) for cooking food, with raised portions (13) in its interior for a cooking with aesthetic characteristics similar to those produced by cooking on a grill, is provided with such raised portions (13) both on its base (11) and on its rim (12'), for improved cooking.
Patent SG-56492-G (SG)
Title: Improvements in and relating to the binding of perforated sheets
IPC: B42B5/10
Filed: 1992-05-29
Abstract: Apparatus for closing wire binding elements (36) of the type formed from a length of wire which is bent to form a series of curved hairpin shaped prongs (2, the curvature of the prongs (2 being such that the element has the appearance of an open sided cylinder with a substantially C-shaped cross-section, the apparatus comprises two opposed 'closing' jaws (9), each having a working surface (30) which is a segment of a cylinder, the diameter of which corresponds to the diameter of a desired binding element (36), when closed, the jaws ( 9) being arranged to rotate in opposite directions about a fixed horizontal axis or pivot centre (24, 24'), the arrangement being such that at the jaws ( 9) pivot a force is applied by their working surfaces (30) to a binding element (36) located therebetween to cause the element (36) to close to a position in which the closed ends or points (26) are brought into the vicinity of the open ends or roots (27), the closing jaws ( 9) being set so that that edge (40) of the working surface (30) which, in use, is located adjacent a bundle of sheets (32) to be bound exactly coincides with the pivot centre (24, 24') of each jaw ( 9) characterised in that means are provided to adjust the position of the pivot centres (24, 24') of each of the jaws ( 9) towards and away from each other so that closing jaws ( 9) of different size may be accommodated.
Patent SG-89186-G (SG)
Title: Concentrating zone method in heterogeneous immunoassays
IPC: G01N33/558
Filed: 1986-11-07
Abstract: Method and apparatus are provided for performing immunoassays employing a device comprising a relatively small test zone referred to as an immunosorbing zone, and a relatively large liquid absorbing zone in liquid receiving relationship with said immunosorbing zone. The immunosorbing zone includes a member of an immunological pair ("mip")-ligand and antiligand-bound to a support. A signal producing system is employed in conjunction with said device having as one component a signal label bound to a mip. The signal producing system provides for production of a detectible signal in the immunosorbing zone in relation to the amount of analyte in a sample.
Patent SG-20395-G (SG)
Title: Phenol preparation process and propylene recovery therefrom
Inventor: FUKUHARA HIROSHI
IPC: C07C39/04
Filed: 1995-02-08
Abstract: Phenol is produced by (a) reacting benzene with propylene to synthesize cumene, (b) oxidizing the cumene of step (a) into cumene hydroperoxide, (c) acid cleaving cumene hydroperoxide into phenol and acetone, (d) hydrogenating the acetone of step (c) into isopropanol and (e) dehydrating the isopropanol of step (d) into propylene. The propylene from step (e) is useful by itself or is recycled from the step (e) to step (a) of the phenol producing process.
Patent IE-830079-L (IE)
Title: Laminates for packaging
IPC: B32B27/00
Filed: 1983-01-17
Abstract: A laminate web, suitable for conversion into a container for degenerative products, is produced from aluminum foil and an extrusion coating of an ethylene/acrylic acid-type copolymer, utilizing a polyacrylic acid chromium complex primer to enhance the bond at the interface. The laminate web will usually be formed into a tube with the copolymer disposed on the product side, which can advantageously be used to package fluoride toothpaste, and the like.
[CA1201050A]
Patent IE-35379-L (IE)
Title: Erythromycylamine compounds
IPC: C07H17/08
Filed: 1971-02-09
Abstract: 1341021 Erythromycylamine compounds LILLY INDUSTRIES Ltd 31 Dec 1970 [13 April 1970] 17527/70 Heading C2A The invention comprises erythromycin A imine and erythromycin B imine. Also, the invention comprises a process for preparing erythromycylamine compounds of Formula I wherein R 1 and R 2 are different and are hydrogen or an amino group, R 3 is a hydrogen atom or a hydroxy group, R 4 is a cladinosyl group and R 5 is a desosaminyl group in which an erythromycin derivative of Formula II wherein R 3 , R 4 and R 5 are as defined above, R 6 is an =N.NH 2 , a grouping of Formula III or an =NH group, and either R 7 is H or C 1 -C 4 alkyl and R 8 is C 1 -C 4 alkyl, phenyl, nitrophenyl or tolyl and R, and R 8 together with the adjacent carbon represents C 5 -C 7 cycloalkylidene, to reduction by means of a metal, e.g. sodium or aluminium, preferably in the form of' an amalgam, or additionally, when R 6 is an = NH group (imino) to reduction by means of a complex metal hydride, e.g. sodium or potassium borohydride or by means of a complex metal hydride, e.g. sodium or potassium borohydride or by means of hydrogen over a catalyst, e.g. a noble metal or a noble metal oxide catalyst. A process for preparing erythromycin A imine or erythromycin B imine comprises subjecting an erythromycin hydrazone or azine derivative of Formula II, wherein R 6 is =N.NH 2 or the grouping III, to reduction by means of a metal of suitable redox potential or additionally when R 6 is an imino group, to nitrosation. Pharmaceutical compositions having antibiotic properties include one of the above erythromycylamine or erythromycylimine compounds in conjunction with a pharmaceutically acceptable carrier.
[GB1341021A]
Patent IE-780212-L (IE)
Title: De-esterification process for cephalosporin preparation.
IPC: A61K31/545
Filed: 1978-02-01
Abstract: p-Nitrobenzyl esters of cephalosporins are reductively cleaved with zinc and alpha -hydroxycarboxylic acids, e.g., the p-nitrobenzyl ester of the cephalosporin antibiotic, cephalexin, is reacted in an inert solvent with zinc and mandelic acid to provide the antibiotic, cephalexin, as the free acid in yields greater than 85 percent.
[US4091214A]
Patent IE-860225-L (IE)
Title: Foam dispensing device
IPC: B65D47/34
Filed: 1986-01-27
Abstract: A device for use with foamable liquids includes a reservoir (13) adapted to contain a quantity of a foamable liquid and an air pump (77) for supplying air to be mixed with the foamable liquid to form a foam. The foamable liquid reservoir is isolated from the air from the air supplying pump. A mixing chamber (53) is provided in which the foamable liquid and air from the air supplying pump can interact to create the foam. A first passage (37,55) leads from the reservoir of foamable liquid to the mixing chamber and a pump (43) is provided for pumping the foamable liquid from the reservoir through the passage to the mixing chamber. A second passage (51) is provided from the air supplying pump to the mixing chamber to introduce air into the mixing chamber.
Patent IE-800249-L (IE)
Title: Heterotricyclic compounds
IPC: A61P37/08
Filed: 1980-02-08
Abstract: Novel compounds of the formula <IMAGE> I wherein A is selected from the group consisting of nitrogen and =CH-, G is selected from the group consisting of <IMAGE> Z is selected from the group consisting of hydrogen and alkyl of 1 to 5 carbon atoms or taken with Y forms a carbon-nitrogen or carbon-carbon bond, Z' is selected from the group consisting of hydrogen and halogen, Y is hydrogen, or taken with Z is a carbon-nitrogen or carbon-carbon bond or taken with X is =O and X is hydrogen or taken with Y is =O, R is selected from the group consisting of hydroxymethyl, formyl, tetrazol-5-yl, N-(tetrazol-5-yl) carbamoyl, aminomethyl and carbamoyl, R1 is selected from the group consisting of hydrogen, halogen and alkoxy of 1 to 5 carbon atoms and its non-toxic, pharmaceutically acceptable acid addition salts having antiallergic activity and their preparation.
[US4333934A]
Patent IE-880278-L (IE)
Title: Cytochrome p-450 enzymes
IPC: C12P17/06
Filed: 1988-02-02
Abstract: Novel cytochrome P-450sca-1, P-450sca-2 and P-450sca-3 enzymes are produced by cultivation of Streptomyces carbophilus SANK 62585, and are suitable for use in hydroxylation processes.
Patent IE-900303-L (IE)
Title: 18-cyanoprogesterone derivatives
IPC: A61P7/10
Filed: 1990-01-26
Abstract: The present invention is directed to a method for the treatment of hyperaldosteronism and related disorders which comprises administering to an appropriate patient an appropriate 18-cyanopregnane.
[EP0380135A2]
Patent IE-38206-L (IE)
Title: Ó-aminoalkyl-4-hydroxy-3-alkylsulphonylmethylbenzyl alcohols
IPC: C07C315/04
Filed: 1973-03-13
Abstract: 1386028 Alkylsulphonylmethylbenzyl alcohols SMITHKLINE CORP 6 March 1973 [20 March 1972] 10768/73 Heading C2C Novel compounds (I) (including salts thereof) where R is straight or branched C 1-5 alkyl, R 1 is branched C 3-5 alkyl, C 3-6 cycloalkyl or C 3-6 cycloalkyl-methyl or a group of Formula (II): R 2 is H, Me or Et, R 3 and R 4 are H, OH or MeO and R 5 is H or Me, are made by hydrogenating compounds (III): 3 - Chloromethyl - 4 - hydroxyacetophenone, 4- hydroxy- and -benzyloxy - 3 - methylsulphonylmethylacetophenones and 4 - benzyloxy - α- bromo - 3 - methylsulphonylmethylacetophenone are also prepared. Pharmaceutical preparations having bronchodilatory action contain (I) as active ingredient. Administration is orally or parenterally.
[GB1386028A]
Patent IE-810412-L (IE)
Title: Card storage magazine
IPC: B42F17/00
Filed: 1981-02-26
Abstract: A guide unit (9) for the flat objects, the unit includes a plurality of guide paths (12,15,16) and movable along one side of a magazine for holding flexible flat objects transversely to the one side in locations spaced along the one side of the magazine, it being thus possible to place a first such guide path (12) opposite a first such location (6), the other guide paths of the guide unit, which diverge away from the first guide path being placed simultaneously opposite the locations (5,7) adjacent the first location. An ejection device (10) moves any flat objects (8) contained in the neighbouring locations (5,7) outward from the one side of the magazine into the divergent paths (15,16) of the guide unit to provide a clear opening before an object is inserted in the first location.