baber/WOPTO huggingface dataset:
Patent NZ-578375-A (NZ)
Title: Flow control valve
Inventor: ESVELDT VINCENT
IPC: E21B21/10
Filed: 2008-02-07
Abstract: A flow control valve (1) includes a housing (2) that is provided with an inlet (3) for admitting a fluid at a certain inlet pressure, a restrictor (4) which allows the fluid to be restricted to a discharge pressure, and an outlet (5) for the fluid. The valve includes an actuator (11) that is externally disposed on the housing (2), a rotatable shaft (13), and a piston (16) which is axially movable in a tubular restrictor cage (15) within the housing (2). The actuator (11) allows a rotation of the shaft (13) to be induced and an axial movement of the piston (16) to be induced by rotating the shaft (13) while a cross-section of the restrictor (4) can be adjusted by axially moving the piston (16). For submarine uses, particularly for extracting crude oil and natural gas via large pipe cross-sections, the flow control valve (1) is further provided with primary magnets 17 mounted on the actuator (11), secondary magnets 18 mounted on the shaft (13), and a roller body screw drive (20) mounted on the shaft (13). A rotation of the actuator (11) is transmitted to the shaft (13) by magnetically coupling the primary magnets to the secondary magnets and is converted into the axial movement of the piston (16) by means of the roller body screw drive (20).
Patent NZ-578804-A (NZ)
Title: Spirocyclic phosphodiesterase inhibitors
Inventor: FELDING JAKOB
IPC: A61P29/00
Filed: 2008-02-26
Abstract: Disclosed are PDE4 inhibiting compounds of formula (I) and pharmaceutically acceptable salts, hydrates, N-oxides, or solvates thereof, wherein the substituents are as described within the specification. Examples of compounds of formula (I) include: N-(3,5-Dichloropyridine-4-yl)-7-methoxy-2',3',5',6'-tetrahydro-spiro[1,3-benzodioxole-2,4'(4H)-pyran]-4-carboxamide; and 2-(3,5-Dichloro-1-oxido-pyridine-4-yl)-1-(7-methoxy-2',3',5',6'-tetrahydro-spiro[1,3-benzodioxole-2,4'-(4H)-pyran]-4-yl)ethanone. Further disclosed is a pharmaceutical composition comprising a compound of formula (I), and the use of a compound of formula (I) in the manufacture of a medicament for the prevention , treatment or amelioration of a disease or condition selected from dermal diseases or conditions, or acute or chronic cutaneous wound disorders.
Patent NZ-579668-A (NZ)
Title: Mobile support for wire fence, assembly with a first and a second mobile support and terrain demarcation
Inventor: VLAAR IWAN YVES
IPC: A01K3/00
Filed: 2008-03-17
Abstract: A mobile support (1) is disclosed for supporting a wire-shaped terrain demarcation on the ground, having a plurality of segments (3) rotatable about an axis (centre of hub (6)). Each segment comprises a spoke (4) having a free end, wherein at least one segment (3) has a greater flexibility in an axial direction than in a direction tangential to the axial direction. A terrain demarcation system and an assembly comprising two such a mobile supports (1) is also disclosed.
Patent NZ-583750-A (NZ)
Title: Novel polysaccharide immunogens from clostridium difficile
Inventor: MONTEIRO MARIO ARTUR
IPC: C12P19/04
Filed: 2008-09-11
Abstract: Disclosed are immunogenic Clostridium difficile cell surface polysaccharides. PS-II is a repeating hexasaccharide unit and PS-1 is a repeating pentasaccharide unit. The polysaccharides can be used in vaccines for treating C. difficile infection and associated diarrhoea in a subject.
Patent NZ-587164-A (NZ)
Title: (dihydro)pyrrolo[2,1-a]isoquinolines
Inventor: VAN RIJN RACHEL DEBORAH
IPC: A61K31/551
Filed: 2009-02-06
Abstract: Disclosed is a compound of formula (I), wherein the substituents are as defined in the specification. The compounds are low molecular weight hormone mimetics that selectively activate the FSH receptor useful in the treatment of infertility.
Patent NZ-587241-A (NZ)
Title: Method, computer program product and system for enabling clinical decision support
Inventor: ONELL ANNICA
IPC: G01N33/564
Filed: 2009-02-06
Abstract: A computer-implemented method and a computer-implemented system for enabling clinical decision support based on pre-processing test results for a plurality of tested biomarkers to provide reduced input data for subsequent input to a computer-based decision engine is disclosed. The system comprises a component (80) for receiving a patient's test results for a plurality of biomarkers; a component (81) for accessing a predefined structure in which available biomarkers are associated with hosts; a component (82) for reducing the test results to input data; a component (83) for assigning a host value to each host in the set of hosts and a component (84). The test result for each biomarker is at a first level of resolution and at least one host is associated with a plurality of biomarkers. The component (82) reduces the test results to input data by mapping the tested biomarkers to the structure, thereby identifying a set of hosts. The host value is determined by the computing device based on the test results of the tested biomarker(s) mapped to the host. The host value is given in a second resolution of values; Component (84) is for providing reduced input data indicative of the set of hosts and the assigned host values for each host in the set for subsequent input to the computer-based decision engine for generating clinical decision support.
Patent NZ-590344-A (NZ)
Title: Isoxazole derivatives and their use as metabotropic glutamate receptor potentiators
Inventor: CACCIOLA JOSEPH
IPC: A61K31/422
Filed: 2009-06-08
Abstract: Disclosed are compounds of Formula I. Specific examples of compounds of Formula I include: 5-(7-chloro-2-((S)-1-cyclopropylethyl)-1-oxo-2,3-dihydro-1H-isoindolin-5-yl)-N-methylisoxazole-3-carboxamide, 5-(2-Isopropyl-7-methyl-1-oxo-2,3-dihydro-1H-isoindol-5-yl)-isoxazole-3-carboxylic acid dimethylamide, and 7-Chloro-2-((S)-1-cyclopropyl-ethyl)-5-[3-(morpholine-4-carbonyl)-isoxazol-5-yl]-2,3-dihydro-isoindol-1-one. Compounds of Formula I are prepared by a method comprising: converting a 4-bromo-aniline to a corresponding nitrile under Sandmeyer reaction conditions; converting the nitrile to an amide by hydrolysing with a base; diazotizing the amide and then hydrolysing with nitrososulphuric acid to provide a benzoic acid; protecting the benzoic acid as a methyl ester, to produce a benzoic acid methyl ester having a benzylic methyl group; monobrominating the benzylic methyl group with N-bromosuccinimide using benzoyl peroxide as the radical initiator to yield 6-substituted 4-bromo-2-bromomethyl-benzoic acid methyl ester; cyclizing the 6-substituted 4-bromo-2-bromomethyl-benzoic acid methyl ester to an 4-bromo isoindolone with an amine; reacting the 4-bromo-isoindolone under Sonagashira conditions with a protected acetylene; deprotecting the acetylene with a base; reacting the deprotected acetylene with ethyl 2-chloro-2-(hydroxyimino)acetate to generate an isoxazole ester, and hydrolysing the ester to the acid and amidating using isobutylchloroformate and N-methyl morpholine and an appropriate amine to generate an amide of Formula I, or, generating an amide of Formula I from an isoxazole ester by reaction with an amine and heating. Compounds of Formula I are useful for treating neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia.
Patent NZ-591742-A (NZ)
Title: Fine-grained filler substances for photometric reaction films
Inventor: KNAPPE WOLFGANG-REINHOLD
IPC: G01N33/52
Filed: 2009-11-06
Abstract: A diagnostic test element (110) for detecting an analyte in a sample of a bodily fluid (126). The element comprises a test field (116) with at least one detection reagent. The detection reagent is adapted to go through at least one detectable change in the presence of the analyte. The test field comprises a detection layer (118) that comprises the detection reagent and the detection layer comprises particles, wherein 90% of all the particles have a size of less than 10 micrometers. The test field has a loading side for applying the sample and the detection side for detecting a change in the detection reagent. The test field further comprises a removal layer (122) arranged on the side of the detection layer facing the loading side, wherein the removal layer comprise a pigment. The body fluid can be whole blood, the analyte can be glucose and the change in the detection reagent can be an optical change. The particles can be sodium aluminium silicate, aluminium or titanium oxide or a nanoparticulate oxidic matieral of silicon oxide, aluminium oxide and titanium oxide. The pigment can be titanium dioxide, zirconium dioxide, barium titanate, barium zirconate or zirconium silicate.
Patent NZ-592371-A (NZ)
Title: Investigating regions beneath the seabed by analysing differences in reflected electromagnetic radiation at two or more frequencies
Inventor: MAAO FRANK AGNAR
IPC: G01V3/12
Filed: 2009-09-15
Abstract: Disclosed is a method of determining the nature of strata beneath the seabed. The method includes applying an electromagnetic field to the strata at two or more different frequencies and detecting an electromagnetic field response at each frequency. The field response is processed by resolving the field responses at the different frequencies and producing differences by subtracting responses at different frequencies. The difference between each of the two or more frequencies is in the range 0.005 to 5 Hz. The phase and/or amplitude of these differences are analysed to derive the nature of the strata. The method can be applied to magnetic as well as electric field measurements of the field response.
Patent NZ-595223-A (NZ)
Title: Combinations including pneumococcal serotype 14 saccharide
Inventor: COSTANTINO PAOLO
IPC: A61K39/02
Filed: 2010-03-24
Abstract: 595223 Discloses an immunogenic composition comprising a meningococcal lipooligosaccaride (LOS) and a pneumococcal serotype 14 capsular saccharide (CS 14, CS14), wherein the LOS and/or CS 14 do(es) not include Galbeta-4GlcNAcbeta1-3Galbeta1-4Glc (LNnT) tetrasaccharide.
Patent NZ-597405-A (NZ)
Title: Shark-derived squalene containing low levels of polychlorinated biphenyl contaminants for use in vaccine adjuvants
Inventor: NOVICKI DEBORAH
IPC: C07C15/24
Filed: 2012-01-04
Abstract: Disclosed is an oil-in-water emulsion adjuvant comprising shark-derived squalene, wherein the emulsion comprises less than 661 picograms of polychlorobiphenyls (PCBs) per gram of squalene expressed as a toxic equivalent (TEQ). Also disclosed are emulsions which contain no hexachlorobiphenyl, pentachlorobiphenyl, or tetrachlorobiphenyl. The emulsions are useful in the preparation of vaccines and other treatment compositions for prevention or treatment of influenza virus, a human immunodeficiency virus (HIV), hookworm, hepatitis B virus, herpes simplex virus, rabies virus, respiratory syncytial virus, cytomegalovirus, Staphylococcus aureus, chlamydia, SARS coronavirus, varicella zoster virus, Streptococcus pneumoniae, Mycobacterium tuberculosis, Bacillus anthracis, Neisseria meningitidis, Epstein Barr virus or human papillomavirus.
Patent NZ-597830-A (NZ)
Title: Methods and compositions for treating cancer comprising abiraterone acetate and prednisone
Inventor: AUERBACH ALAN H
IPC: A61K45/06
Filed: 2007-08-23
Abstract: 597830 Disclosed herein is the use of abiraterone acetate (II) and prednisone in the treatment of prostate cancer, and refractory cancer, and a pharmaceutical composition thereof. Specifically wherein the therapeutically effective amount of abiraterone acetate is from about 50 mg/day to about 2000 mg/day, more specifically 500 mg/day to 1500 mg/day, more specifically 100 mg/day. Additionally wherein the abiraterone acetate is prepared to be administered in at least one oral dosage form comprising 250 mg of abiraterone acetate. Specifically wherein the therapeutically effective amount of prednisone is from about 0.01 mg/day to about 500 mg//day, more specifically from about 10 mg/day to about 250 mg/day.
Patent NZ-601370-A (NZ)
Title: Cooling and processing biomass materials
Inventor: MEDOFF MARSHALL
IPC: C10G1/00
Filed: 2009-07-15
Abstract: ABSTRACT - 601370 The disclosure relates to a method of producing an alcohol comprising ethanol or n-butanol, which comprises: cooling the biomass material to 280°K (6.85°C) or less; after cooling grinding or comminuting the cooled-biomass material to reduce the recalcitrance of the biomass material; and processing the material to produce a product that is chemically different from the biomass material; wherein processing comprises contacting the material with an enzyme and/or a microorganism, and wherein the method further comprising irradiating the biomass material using an electron beam wherein cooling is performed prior to irradiating and optionally after irradiating, and wherein the biomass material is selected from the group consisting of wood, grasses, rice hulls, bagasse, jute, hemp, flax, bamboo, sisal, abaca, straw, corn cobs, coconut hair, algae, seaweed, and mixtures of any of these.
Patent NZ-606389-A (NZ)
Title: Method and device for the sterile connection of pipes
Inventor: SCHWALM MICHAEL
IPC: A61M39/10
Filed: 2011-08-05
Abstract: 606389 Disclosed is device (10) for sterile connection of medical tubes (1a, 1b) and for quick connections which generate minimal waste. The device (10) comprises providing a first receiving device (20a); a second receiving device (20b); heating means and separating means. The first receiving device (20a) receives a first tube (1a). The second receiving device (20b) receives a second tube (1b). The heating means heats a separating region of the first tube (1a) arranged on the first receiving device (20a) and a separating region of the second tube (1b) arranged on the second receiving device (20b). The separating means separates each of the first (1a) and second tubes (1b) in the heated separating region into a first and a second tube portions. The first (20a) and second (20b) receiving devices are each designed to hold the respective first tube portion such that it extends at least in part along a plane and at least one of the two receiving devices (20a, 20b) is mounted rotatably about an axis of rotation that runs at least approximately perpendicularly to the plane. The device (10) is deigned such that after separation of the first (1a) and second (1b) tubes, an end of the first tube portion of the first tube (1a) can be brought into mechanical contact with an end of the first tube portion of the second tube (1b) with rotation of the first and/or second receiving device (20, 20b) about the axis of rotation.
Patent NZ-615009-A (NZ)
Title: Flash defrost system
Inventor: DAVIES THOMAS WILLIAM
IPC: F25B41/04
Filed: 2012-02-10
Abstract: Disclosed is a vapour compression refrigeration system with a defrost circuit that includes a compressor (1) arranged to re-circulate refrigerant through a condenser (2), an expansion device (4) and an evaporator (5). To achieve rapid thermodynamically efficient defrosting of the evaporator, hot refrigerant from the condenser is stored in a defrost receiver (6) before passing through the expansion device (4). In a defrost phase, a valve arrangement (7-10) forms a closed defrost circuit connecting the evaporator (5) to the defrost receiver (6) via defrost valve (10) to allow hot fluid to pass from the defrost receiver to the evaporator and liquid refrigerant in the evaporator flows to the defrost receiver (6) via drain valve (9). In a pre-defrost phase, the valve arrangement closes the fluid input to the evaporator (5) and the compressor operates to partially evacuate the evaporator before the evaporator is connected to the defrost receiver, so that flash flooding of the evaporator with hot vapour occurs. A phase change medium (11) may be included to store heat from the condenser output and return it to the evaporator during defrost. Additional heat may be supplied to the defrost liquid to further increase the defrost speed.
Patent NZ-619325-A (NZ)
Title: Combinations comprising a fungicidal strain and an active compound
Inventor: SCHOFL ULRICH
IPC: A01N63/02
Filed: 2008-09-16
Abstract: Disclosed is a fungicidal composition for controlling phytopathogenic harmful fungi, comprising 1) a fungicidal strain (I) selected from a) the Bacillus substilis strain with NRRL Accession No. B-21661, and b) the Bacillus pumilus strain with NRRL Accession No. B-30087, or a mutant of these strains having all the identifying characteristics of the respective strain, or a metabolite produced by the respective strain that exhibits activity against plant pathogenic fungi, and 2) at least one other fungicide selected from the active compound group: carbamates selected from the group consisting of propamocarb, and propamocarb hydrochloride; in a synergistically effective amount.
Patent NZ-619614-A (NZ)
Title: Insulated container
Inventor: LESER CHRIS K
IPC: B65D81/38
Filed: 2012-06-07
Abstract: Disclosed is an insulated container with a body of an insulating polymer where localized plastic deformation in at least one selected region of the body is enabled by reducing the polymer density by foaming the region. The insulative cup comprises a body including a sleeve-shaped side wall and a floor coupled to the body to define an interior region bounded by the sleeve-shaped side wall and the floor. The body comprises a sheet comprising insulative cellular nonaromatic polymeric material configured to provide a means for enabling localized plastic deformation in at least one selected region of the body to provide a plastically deformed first material segment having a first density located in a first portion of the selected region of the body and a second material segment having a second density lower than the first density located in an adjacent second portion of the selected region of the body without fracturing the insulative cellular non-aromatic polymeric material so that a predetermined insulative characteristic is maintained in the body. The insulative cellular non-aromatic polymeric materials comprises a polypropylene base resin having a high melt strength, a polypropylene homopolymer resin, at least one nucleation agent, and gas means for expanding the resins to reduce density.
Patent NZ-624933-A (NZ)
Title: Aqueous dispersions and precursors thereof
Inventor: PALAIKIS LIANA VICTORIA
IPC: C09K21/14
Filed: 2012-12-19
Abstract: Disclosed herein is a powder composition including starch, acrylic acid homopolymer salt, vegetable oil and clay. The powder composition forms an aqueous dispersion having a neutral pH when added to water and is capable of clinging to a surface. The composition may be used as a fire-fighting composition.
Patent NZ-708382-A (NZ)
Title: Cycloalkyl bis-thiadiazole inhibitors of glutaminase and their use as therapeutic agents
Inventor: SAUNDERS JEFFREY O
IPC: C07D417/14
Filed: 2013-11-21
Abstract: Provided are compounds of formula (II), which can inhibit glutaminase. Pharmaceutical compositions comprising these compounds and uses as glutaminase inhibitors for treating cancers thereof are also provided.
Patent NZ-711541-A (NZ)
Title: Camera cleaning system and method for a milking system
Inventor: ERIKSSON JAN
IPC: A01K1/12
Filed: 2012-11-29
Abstract: Disclosed is a camera cleaning system for a milking system. The milking system comprises a moving arrangement (19), a plurality of milking stalls (19a) arranged thereon for housing a plurality of animals (15) during milking thereof, a robot (10) for performing an animal related operation with respect to the animals (15) in the milking stalls passing by the robot (10), and a camera (14) in response to signals from which the robot (10) is configured to move. The camera cleaning system has a cleaning arrangement (17), a rinsing arrangement (17a) and control means (18). The cleaning arrangement (17) is arranged to clean the lens arrangement of the camera (14) according to a first cleaning scheme. The rinsing arrangement (17a) is arranged to clean the lens arrangement of the camera (14) according to a second cleaning scheme. The cleaning according to the first cleaning scheme is more time consuming than the cleaning according to the second cleaning scheme. The control means (18) is arranged to control the cleaning arrangement (17) and the rinsing arrangement (17a) such that the cleaning according to the first cleaning scheme is performed more rarely than the cleaning according to the second cleaning scheme.
Patent NZ-727358-A (NZ)
Title: Indazole inhibitors of the wnt signal pathway and therapeutic uses thereof
Inventor: HOOD JOHN
IPC: A01N43/54
Filed: 2013-03-13
Abstract: Substituted indazol-imidazo-pyridin derivative compounds of formula (I) that are suitable for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of these indazol-imidazo-pyridin compounds or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, Alzheimer’s disease, lung disease and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components.
Patent NZ-728253-A (NZ)
Title: Medical temperature control apparatus
Inventor: KLAUS JANISCH
IPC: A61F7/00
Filed: 2017-01-12
Abstract: The invention relates to a medical temperature control apparatus comprising a housing, at least one fluid supply device, one temperature control device 2, 3 for the fluid, one fluid outflow device 27 and one pump device 31 for the fluid. The medical temperature control apparatus is particularly provided for the connecting of a temperature-control cuff applied to areas of a patient’s body for heat treatment or cold treatment. The pump device 31 is configured as a displacement pump, preferably as a gear pump, and a pressure limiting device 19, 35 is provided which keeps the pressure of the fluid flowing out of the housing within a predetermined range. The pressure limiting device is a throttle device and comprises a throttle line which is fluidly coupled to the pump device at one end and to the fluid supply device at the other end. This thereby prevents excessive pressure from developing in the fluid outflow device 27 which might damage the cuff.
Patent NZ-740157-A (NZ)
Title: Methods of improving myocardial performance in fontan patients using udenafil compositions
Inventor: YEAGER JAMES L
IPC: A61K31/522
Filed: 2015-06-30
Abstract: The present invention relates generally to the field of using udenafil or a pharmaceutically acceptable salt thereof in patients who have undergone the Fontan operation. Udenafil is administered to patients whose exercise capacity is adversely affected due to a decline in heart function after Fontan palliation, with a total daily dose of 125 mg to 175 mg. Improvement of exercise capacity is determined by maximum oxygen uptake at maximum exercise output (VO2 measurement).
Patent NZ-744786-A (NZ)
Title: Recombinant adenovirus vectored fmdv vaccines and uses thereof
Inventor: Widener Justin
IPC: C12N15/86
Filed: 2017-01-30
Abstract: The present invention encompasses FMDV vaccines or compositions. The invention encompasses recombinant vectors encoding and expressing FMDV antigens, epitopes or immunogens which can be used to protect animals, in particular ovines, bovines, caprines, or swines, against FMDV. Particularly, the present invention relates to the removal of a portion of the natural FMDV sequence resulting in the combination of partial structural proteins such as P1-2A-2B’-3B’-3C or P1-2A-2B-2C’-3A’-3B-3C. This can be applied to different FMDV serotypes such as A24, A12, O1M, Irn or Asia.