baber/WOPTO huggingface dataset:
Patent MX-2010000617-A (MX)
Title: Compounds and methods for kinase modulation, and indications therefor.
Inventor: ARTIS DEAN R
IPC: C07D231/40
Filed: 2008-07-16
Abstract: Compounds of formula I active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases. Formula (I) wherein Ar is optionally substituted heteroaryl; R2 is hydrogen, lower alkyl or halogen; U is selected from the group consisting of -S(O)2-, -C(X)-, -C(X)-N(R10)-, and -S(O)2-N(R10)-; R3 is optionally substituted lower alkyl, optionally substituted C3.6 cycloalkyl, optionally substituted heterocycloalkyl, optionally substituted aryl or optionally substituted heteroaryl; and wherein R1, R3, R4, m, L1, X R10 are as described herein.
Patent MX-2010002056-A (MX)
Title: Breathing-gas delivery and sharing system and method.
Inventor: FUHRMAN BRADLEY P
IPC: A61M16/00
Filed: 2008-08-22
Abstract: A device, system, and method for isolating a ventilator from one or more patients in which the delivery conditions of gas delivered to an isolation device from a ventilator may drive the delivery of breathing-gas delivered to one or more patients, the breathing-gas having the same or different delivery conditions. In one embodiment, an isolation device may have a housing and a movable partition. The movable partition may be joined to the housing, The movable partition may have a patient side on a first side of the partition and an actuating side on a second side of the partition. The isolation device may include an inlet pressure regulator on the actuating side and/or an exhaust pressure regulator on the patient side. These regulators may alter the delivery conditions (including, but not limited to, pressure and volume) of breathing-gas delivered to a patient.
Patent MX-2010002463-A (MX)
Title: Plants having increased yield-related traits and a method for making the same.
Inventor: FRANKARD VALERIE
IPC: A01H5/00
Filed: 2008-09-19
Abstract: The present invention relates generally to the field of molecular biology and concerns a method for increasing various plant yield-related traits by increasing expression in a plant of: (i) a nucleic acid sequence encoding a <u>G</u>rowth-<u>R</u>egulating<u>F</u>actor (GRF) polypeptide; and of (ii) a nucleic acid sequence encoding a <u>sy</u>novial sarcoma <u>t</u>ranslocation (SYT) polypeptide, wherein said yield-related traits are increased relative to plants having increased expression of one of: (i) a nucleic acid sequence encoding a GRF polypeptide, or (ii) a nucleic acid sequence encoding a SYT polypeptide. The present invention also concerns plants having increased expression of (i) a nucleic acid sequence encoding a GRF polypeptide; and of (ii) a nucleic acid sequence encoding a SYT polypeptide, wherein said plants have increased yield-related traits relative to plants having increased expression of one of: (i) a nucleic acid sequence encoding a GRF polypeptide; or (ii) a nucleic acid sequence encoding a SYT polypeptide. The invention also provides constructs useful in the methods of the invention.
Patent MX-2010004047-A (MX)
Title: A system and method for reshaping soft tissue.
Inventor: COHEN ADI
IPC: A61F2/12
Filed: 2008-10-22
Abstract: A system and method for soft tissue (such as breast, buttocks tissues, arms and neck lifting and shaping/reshaping) shaping is provided, comprising a cradling member for cradling soft tissue and an anchoring system for fixing the cradling member to posture tissue in at least one location. The cradling member has a top side and a bottom side, wherein at least one of the top side or bottom side may be fitted with at least one inflatable compartment.
Patent MX-2010012043-A (MX)
Title: Dose counter and lockout mechanism.
Inventor: SUGIANTO ALFRED
IPC: A61M15/00
Filed: 2009-05-07
Abstract: A medicament dispenser, in particular a metered dose inhaler, which is able to count the number of time the dispenser is activated and then disable the device, which then prevents any additional medicament from being dispensed. Additional embodiments include a medicament dispenser which are adapted to display either the number of activations that have occurred or the number of activations remaining.
Patent MX-2010012260-A (MX)
Title: Inhibitors of protein kinases.
Inventor: MICHAELIDES MICHAEL R
IPC: C07D487/04
Filed: 2008-12-11
Abstract: Compounds that inhibit Aurora-kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed. One embodiment of this invention, therefore, pertains to compounds that inhibit Aurora-kinases, the compounds having formula I and therapeutically acceptable salts thereof.
Patent MX-2010012505-A (MX)
Title: Method and system for manufacturing intaglio printing plates for the production of security papers.
Inventor: PERRIER JACQUES
IPC: B23K26/02
Filed: 2009-05-05
Abstract: There is described a method for manufacturing intaglio printing plates for the production of security papers, wherein a laser beam (2) is used to engrave intaglio printing patterns (3, 3.1, 3.2, 3.3) directly into the surface of a laser- engravable, especially metallic, printing plate medium (1 ), wherein laser engraving of the printing plate medium (1 ) is carried out layer by layer in several individual engraving steps performed one after the other in register so that the intaglio printing patterns (3, 3.1, 3.2, 3.3) are gradually engraved into the surface of the printing plate medium (1 ) up to desired engraving depths, the surface of the engraved printing plate medium (1 ) being cleaned from residues of the laser engraving process following and between each individual engraving step.
Patent MX-2010013944-A (MX)
Title: Substituted pyrimidone derivatives.
Inventor: SAADY MOURAD
IPC: A61K31/519
Filed: 2009-06-25
Abstract: Pyrimidone derivatives of formula (I) wherein: R1 represents a 4-pyridine ring; R2 represents a hydrogen atom; R3 represents a hydrogen atom; R4 represents : a hydrogen atom; a phenyl ring, this ring being optionally substituted by 1 to 4 substituents selected from a C1-6 alkyl group, a halogen atom, a C1-2 halogenated alkyl group, a hydroxyl group, a C1-6 alkoxy group, a C1-2 halogenated alkoxy group, R5 represents a hydrogen atom, a C1-6 alkyl group, a 4-pyridine group, a phenyl group, these groups being optionally substituted, R6 represents a hydrogen atom, a C1-6 alkyl group, a benzyloxy group, a phenyl C1-6 alkyl group, these groups being optionally substituted, in form of a free base or of an addition salt with an acid. Use in therapeutic.
Patent MX-2011005794-A (MX)
Title: Device and method for catalytic gas phase reactions and use thereof.
Inventor: SCHWEFER MEINHARD
IPC: B01J19/00
Filed: 2009-12-01
Abstract: The invention relates to improved reactors for catalytic, exothermal gas phase reactions having an entrance zone (1), a reaction zone (2) comprising at least one catalyst (4) and an outlet zone (3) for the product gas, viewed in the flow direction of a reactant gas comprising at least one oxidizing agent and at least one component to be oxidized. The reactors have means, such as insulating jackets (6) and/or devices for transporting coolant, at least in the region of the entrance zone (1), wherein said coolants reduce the transport of heat generated in the reaction zone (2) into the entrance zone (1) and thus reduce the risks of advanced ignition of the reactant gas mixture used or the development of undesired secondary reactions in the entrance zone (1) and/or wherein the inside walls of the reactor are designed from inert material, at least in the region of the entrance zone (1). The reactant gas enters the entrance zone (1) as a homogenous gas mixture, with regard to the material composition thereof, via one or more supply lines (30). The reactors can be used particularly for ammonia oxidation, such as in nitric acid systems, in which preferably honeycombed transition metal catalysts having small cross-sections are used as the platinum nets that are conventionally employed.
Patent MX-2011009934-A (MX)
Title: A medicinal antibacterial cream and a process to make it.
Inventor: VANANGAMUDI SULUR SUBRAMANIAM
IPC: A61K9/107
Filed: 2010-03-24
Abstract: The present invention relates to a composition for treating bacterial skin infections along with skin rejuvenation. More particularly, the present invention relates to a pharmaceutical cream comprising a biopolymer, and an antibacterial active ingredient. It discloses a composition for treating bacterial skin infections along with skin rejuvenation containing a) a biopolymer in the form of a) chitosan, b) an active pharmaceutical ingredient (APIs) used in treating bacterial skin infections,. c) a cream base containing primary and secondary emulsifiers, waxy materials, co-solvents, acids, preservatives, buffering agents, anti oxidants, chelating agents, and humectants, and d) water. The active ingredients, namely chitosan, and an antibacterial agent, are incorporated in cream base for use in treating bacterial skin infections.
Patent MX-2011010185-A (MX)
Title: An improved process for the rapid hydrolysis of high solids biomass.
Inventor: COMETTINI MARCO COTTI
IPC: C12P19/02
Filed: 2010-03-31
Abstract: The process for the hydrolysis of ligno-cellulosic biomass comprises the steps of A) Contacting a ligno-cellulosic feedstock, the feedstock comprised of biomass having a dry content and water with at least a portion of a solvent, the solvent comprised of water soluble hydrolyzed species; wherein at least some of the water soluble hydrolyzed species are the same as the water soluble hydrolyzed species obtainable from the hydrolysis of the biomass in the feedstock; B) maintaining the contact between the feedstock of the feedstock stream and the solvent at a temperature in the range of 20Â°C to 200Â°C for a time in the range of 5 minutes to 72 hours to create a hydrolyzed product from the biomass in the feedstock.
Patent MX-2011012021-A (MX)
Title: Immortalized avian cell lines and use thereof.
Inventor: BALLOUL JEAN-MARC
IPC: A61K39/12
Filed: 2010-05-11
Abstract: The present invention relates to specific immortalized avian cell lines expressing telomerase reverse transcriptase (TERT), and exhibiting distinct biologics production patterns. More particularly, the present invention relates to immortalized avian cell line capable of either amplifying Flaviviridae but not capable of amplifying Vaccinia virus strain Copenhagen(VV-COP) nor Modified Vaccinia virus Ankara (MVA), or capable of amplifying both Flaviviridae and Poxviridae. The invention further relates to the use of said immortalized avian cell lines and related methods for producing biologics, including viruses and proteins.
Patent MX-2011013405-A (MX)
Title: Method for obtaining novel derivatives of naphthalene for the in vivo diagnosis of alzheimer's disease.
Inventor: CARRAZANA MARQUIZA SABLON
IPC: C07C43/20
Filed: 2010-04-17
Abstract: The invention relates to chemistry and in particular to the field involved in the organic synthesis of compounds belonging to the category of naphthalene or bicyclic aromatics, used in the detection of amyloid plaques. These novel naphthalene derivatives have general formula: (I), (II), wherein: R represents groups that are independent of one another. In formula (I), R1 represents -alkylenyl-C(O)NH- alkylenyl-R3, -alkylenyl-C(O)O-R4; R3 represents -COOH, -OH, -SH, -NH2, -alkyl-NH, -alkyl-/V- dithiocarbamate of salts of alkaline earth metals; R4 represents H, succinimide group; and R2 represents -H, - alkyl. In formula (II), R1 represents -alkyl, -alkylenyl-halide, -alkylenyl-hidroxyl, -alkylenyl-O- arylsulfonate, alkylenyl-O-alkylsulfonate; R2 represents-halide, -alkylenyl-O-arylsulfonate, - alkylenyl-O-alkylsulfonate, -alkylenyl-halide, -CH(O), -HC=C(CN)2, -HC=CHNO2, - alkylenyl-NH2, -alkylenyl-NH-alkyl, -alkylenyl-alkyl-Î¿/-dithiocarbamate of alkaline salts. The terms "alkyl" and "alkylenyl" refer to linear or branched aliphatic chains, preferably with between 1 and 4 carbon atoms, and the term halide refers to fluorine, bromine or iodine. These compounds are neutral, lipophilic and of low molecular weight, allowing same to pass through the blood-brain barrier and adhere to amyloid plaques. The invention relates to methods for obtaining naphthalene derivatives in good yields, which are practical, economical and can be adapted to larger-scale manufacture. We are not aware of any reference in the prior art to the compounds presented in this application.
Patent MX-2012002599-A (MX)
Title: Cassette with infusion set containing spring-biased anti-freeflow mechanism for peristaltic infusion pump.
Inventor: HIGGINS JAMES ALLEN
IPC: A61M5/142
Filed: 2010-07-08
Abstract: Flow control devices.- In a general embodiment, the present disclosure provides a cassette (30) comprising a housing having a flow restrictor (34), and a tube (36) attached to the housing and positioned adjacent the flow restrictor. The flow restrictor may be so constructed and arranged to rotate from a first position in which the flow restrictor prevents fluid flow through the tube to a second position in which fluid is able to flow through the tube when the cassette is positioned inside a pumping device. As a result, the cassette is designed to prevent free flow of fluid when an enteral feeding tube set is not installed in a pumping device.
Patent MX-2012005491-A (MX)
Title: Flue gas treatment system.
Inventor: KOSS PETER U
IPC: C01B32/50
Filed: 2010-11-11
Abstract: The present invention relates to a gas cleaning system for cleaning a gas stream containing carbon dioxide and sulfur dioxide, said gas cleaning system comprising: a pre-conditioning section (3); a CO<sub>2</sub> removal stage (5); and a post- conditioning section (4); said pre-conditioning section comprising at least two gas- liquid contacting devices (19,20) arranged upstream of the CO<sub>2</sub> removal stage (5) with respect to the flow direction of the gas; and said post-conditioning section comprising at least two gas-liquid contacting devices (30,31) arranged downstream of the CO<sub>2</sub> removal stage with respect to the flow direction of the gas. The present invention further relates to a method for cleaning a gas stream containing carbon dioxide and sulfur dioxide, said method including removing, at least partly, carbon dioxide from the gas stream in a carbon dioxide removal step by bringing the gas stream into contact with a liquid comprising ammonia; contacting the gas stream with liquid in at least two steps upstream of the carbon dioxide removal step; and contacting the gas stream with liquid in at least two steps downstream of the carbon dioxide removal step.
Patent MX-2012007676-A (MX)
Title: Antibody formulation.
Inventor: MAHLER HANNS-CHRISTIAN
IPC: A61K47/26
Filed: 2010-12-23
Abstract: This invention relates to a pharmaceutical formulation of an antibody against Epidermal Growth Factor Receptor (EGFR), a process for the preparation and uses of the formulation.
Patent MX-2012008433-A (MX)
Title: Blanking die assembly with at least one device for differentially rotating the blanking unit.
Inventor: PERUCCHI MAURIZIO
IPC: B21D28/00
Filed: 2012-07-19
Abstract: A sheet metal blanking die assembly (1), comprising a lower part (3), an upper part (5) and guide columns (7) arranged to maintain said parts (3, 5) aligned during the movement of the upper part (5) relative to the lower part (3), the die upper part (5) and lower part (3) of the die assembly (1) presenting flat parallel mutually opposing horizontal portions (11, 13), the lower flat portion (13) being adapted to receive the sheet metal, the upper flat portion (11) presenting a plurality of punches (17) which project downwards from it at the moment of blanking when the die assembly (1) is closed by the action of a press, blanking recesses (19) being present in said flat lower portion (13) to receive the respective punches (17), the die assembly (1) presenting at least one differential rotation device for a blanking unit positioned to correspond with at least one blanking position (18, 19, 20), said device comprising a punch holder (31), a guide means (35) and a die (37); said punch holder (31) guide (35) and die (37): - forming a blanking unit (41) adapted to rotate about an axis X within said upper part (5) and lower part (3) of the die assembly (1); - presenting respectively further seats (47, 49 and 51) to house centring means (33), - being able to rigidly rotate mutually by means of said centring means (33).
Patent MX-2012008481-A (MX)
Title: Hydraulic device including a spool valve and method of use thereof.
Inventor: DOYLE MARK
IPC: F15B13/02
Filed: 2011-01-21
Abstract: A spool valve for controlling fluid communication among hydraulic cylinders operating control and slave portions of a surgical device. The spool valve may be used to disconnect the control and the slave portions from one another such that there is no fluid communication between the control and slave portions. The spool valve may be used to engage or allow fluid communication between the control and slave. The spool valve may also be used to allow fluid communication between the slave and control portion and a fluid reservoir, thus allowing the hydraulic system to replenish fluid lost to evaporation, leakage, or other escape. The spool valve includes a body portion having at least two ports and a spool having at least one passageway moveable to a position so as to communicate with the at least two ports.
Patent MX-2013001056-A (MX)
Title: Imidazoline 8-hexyloxyphenyl-2-imidazoline, 8-nonyloxyphenyl-2-im idazoline and 7-nonyloxyphenyl-2-imidazoline and 7-nonyloxyphenyl-2-imidazoline and obtention process.
Inventor: ARELLANO ALICIA RUMUALDA REYES
IPC: A61P31/00
Filed: 2013-01-25
Abstract: The present invention is related to the compounds 7-NONYLOXYPHENYL-2-IMIDAZOLINE AND 7-NONYLOXYPHENYL-2-IMIDAZOLINE and process for obtaining same. These compounds are obtained by a two-step process: an alkylation of 3ùhydroxybenzaldehyde with the corresponding alkyl halide obtaining 81% of isolated yield and a cyclization performed by ethylenediamine, potassium carbonate, triethylamine, iodine and t-butanol, obtaining quantitative yield. Both compounds, 7-NONYLOXYPHENYL-2-IMIDAZOLINE AND 7-NONYLOXYPHENYL-2-IMIDAZOLINE, have in vitro activity against Tripanosoma cruzi; the compounds have been evaluated over blood Trypomastigote from the NINOA and INC-5 strains, in the latter strain presenting an activity practically equal to the drugs of clinical use Nifortimox and Benznidazol at concentrations of 19.2 and 38.4 ÁM. The compounds 7-NONYLOXYPHENYL-2-IMIDAZOLINE AND 7-NONYLOXYPHENYL-2-IMIDAZOLINE, due to the chemical characteristics thereof could lead to molecular gels, which are formed by nanoparticles.
Patent MX-2013001327-A (MX)
Title: Use of hmgb1 as' a biological marker of bowel inflammatory conditions, non-invasive method for its detection in fecal samples and kit thereof.
Inventor: CUCCHIARA SALVATORE
IPC: G01N33/53
Filed: 2011-08-01
Abstract: A non-invasive method for measuring a bowel inflammatory condition in humans through the presence of HMGB1 protein in fecal extracts and the involvement of such protein in the pathogenesis of chronic inflammatory bowel diseases, more specifically of Crohn's Disease (CD) and of ulcerative colitis (UC), comprising an analysis protocol to detect the HMGB1 presence in feces through Western blot assay or ELISA assay using an appropriate antigen-antibody. The invention also comprises the colorimetric kit for implementing such a method.
Patent MX-2013002961-A (MX)
Title: Leds lamp for photo stimulating platelet-rich plasma.
Inventor: PÉREZ MANUEL GONZÁLEZ
IPC: A61N5/01
Filed: 2013-03-15
Abstract: The present invention is related to a Led lamp, particularly referring to a lamp for photo stimulating plasma, which main target is to photo activating cells (platelets) so that the physician, researcher or user may use them in a medical treatment. Essentially, the cells are activated according to the frequencies of the electromagnetic waves and the power emitted by the LEDs, which are simultaneously controlled by an electric-electronic circuit; this may avoid unwanted biochemical and chemical reactions.
Patent MX-2013003293-A (MX)
Title: Thermal cycler.
Inventor: COBB BEN
IPC: B01L7/00
Filed: 2011-09-22
Abstract: We describe a thermal cycler comprising a Peltier- type thermoelectric element (36) used for cooling a sample block (34), and a non- Peltier- type heating device (38) for heating the sample block. The cycler also includes a heat sink (28) connected to the Peltier- type element by a heat pipe (40), which permits thermal energy to transfer from the Peltier- type element to the heat sink. This configuration operates more efficiently than conventional thermal cyclers which use Peltier- type elements for heating and cooling, and allows a more rapid cycling time as well as operation in a wider range of ambient temperatures. Certain embodiments utilise the Peltier- type element as a thermal gate to reduce thermal loss during heating when the Peltier- type element is switched off.
Patent MX-2013006244-A (MX)
Title: Method and apparatus for determination of system parameters for reducing crude unit corrosion.
Inventor: BANKS RODNEY H
IPC: G01N21/75
Filed: 2012-04-26
Abstract: The invention provides a method and apparatus for determining the amount of various materials in a liquid sample. Because the apparatus is particularly resilient It can be used repeatedly with very harsh liquid samples such as boot water from an oil refinery. The apparatus uses at least one volume and/or concentration independent optical analysis method to determine at least one of: the pH, amount of chloride, and/or amount of iron in the sample. The optical property can be eolorimetrie, fluorescent, or both and result from adding dyes, complexlrsg agents, turbidity inducing compounds, and other optically effecting reagents to the sample. Because the measurements are concentration and volume independent they can be done continuously, quickly, and avoid the inconvenient start and stop procedures in prior art measurement regimens. The method further includes using a BDD cell to oxidize materials (such, as sulfoxy compounds) that would otherwise interfere with the optical analysis and/or to sparge the sample with gas.
Patent MX-2013012236-A (MX)
Title: Container forming apparatus and method.
Inventor: AGANOVIC AMER
IPC: B31B50/04
Filed: 2013-10-18
Abstract: An apparatus for forming a container from a blank is provided. The apparatus includes a blank feeder assembly, and a compression assembly including a mandrel assembly, an upper folding arm assembly including a plurality of folding arms moveable between a first position and a second position, a compression plate, and a rollover arm assembly.
Patent MX-2013013031-A (MX)
Title: Implantable medical device having enhanced endothelial migration features and methods of making the same.
Inventor: PALMAZ JULIO C
IPC: A61F2/01
Filed: 2012-05-09
Abstract: An implantable medical device having enhanced endothelial migration features, generally comprises: a structural member including cross-section having a leading edge and a trailing edge interconnected by a third surface region, the leading edge including a second surface region in a generally curvilinear cross-section, and the trailing edge including a fourth surface region in a generally curvilinear cross-section, whereby fluid flow over the second surface region generate shear stress at the second surface region without an eddy region in the second surface region.
Patent MX-2013014588-A (MX)
Title: Absorbent structure for absorbent articles.
Inventor: KREUZER CARSTEN HEINRICH
IPC: A61F13/532
Filed: 2012-06-08
Abstract: Absorbent structures for diapers are provided, comprising, immobilized onto a supporting sheet, an absorbent layer with absorbent material containing superabsorbent polymer particles and therein, in the front region, a first and a second substantially longitudinal channel, each being free of said superabsorbent polymeric particles, for improved fit and/or performance throughout the use thereof.