baber/WOPTO huggingface dataset:
Patent CA-2343656-A1 (CA)
Title: Trex, a novel gene of traf-interacting ext gene family and diagnostic and therapeutic uses thereof
Inventor: SATO TAKA-AKI
IPC: C12Q1/68
Filed: 1999-09-17
Abstract: This invention provides an isolated nucleic acid molecule encoding a Tumor necrosis factor Receptor-Associated Factor (TRAF) protein-interacting hereditary multiple extoses (TREX) protein. This invention also provides vectors comprising the isolated nucleic acid molecule encoding a TREX protein.  This invention further provides a purified TREX protein and antibodies thereto. This invention provides oligonucleotides comprising a nucleic acid molecule of at least 15 nucleotides capable of specifically hybridizing with a unique sequence included within the sequence of an isolated nucleic acid molecule encoding TREX protein. This invention provides an antisense oligonucleotide comprising a sequence capable of specifically hybridizing with a unique sequence included within a genomic DNA molecule encoding a Tumor necrosis factor Receptor-Associated Factor (TRAF) protein-interacting hereditary multiple extoses (TREX) protein. This invention provides a monoclonal antibody directed to an epitope of a TREX protein. This invention provides methods of inhibiting TREX protein interaction with a TRAF protein;  of inhibiting overexpression of TREX protein; of inhibiting growth of a tumor;  of treating abnormalities in a subject associated with overexpression of TREX.  This invention provides pharmaceutical compositions comprising oligonucleotides effective to prevent overexpression of a TREX protein or antibodies effective to block binding of a TREX protein to a TRAF protein;  screening for compounds which inhibit TREX protein and TRAF protein binding;  of detecting predispositions to cancers comprising TREX mutations; and of diagnosing cancer comprising TREX mutations.
Patent CA-2345450-A1 (CA)
Inventor: COHEN MICHAEL
IPC: C04B35/111
Filed: 2001-04-27
Abstract: The invention provides a sintered, alumina ceramic product comprising about 90-97.5 w/w% Al2O3, about 0.5-1.0 w/w% MgO, about < 0.05-1.0 w/w% SiO2, about 4.5-7.5 w/w% ZrO2 and about 0.07-0.13 w/w% HfO2.
Patent CA-2345994-A1 (CA)
Inventor: BOSETTO ANTONIO
IPC: A61M1/34
Filed: 2000-07-28
Abstract: A dialysis machine comprises: means for calculat-ing (60) a filtration factor (FF) as a function of the ultrafiltration rate (UFR) and of a plasma flow rate (Q p); first comparison means (65) for comparing the filtration factor (FF) with a limit value of admissibility; and signaling means (70) for generating a signal (A) indicating the result of the comparison.
Patent CA-2346697-A1 (CA)
Inventor: WASOWICZ JANET M
IPC: G10L15/00
Filed: 1999-10-07
Abstract: L'invention se rapporte à un outil d'apprentissage permettant le contrôle d'au moins un traitement auditif, d'une sensibilisation phonologique, d'un traitement phonologique et de l'aptitude à la lecture d'un sujet. Cet outil d'apprentissage peut faire appel à divers jeux graphiques (102) conçus pour développer la capacité d'un sujet à réagir à un ensemble particulier de traitements auditifs, à une sensibilisation phonologique, à un traitement phonologique ainsi que pour développer son aptitude à la lecture. Ce système peut mettre en oeuvre la technologie de reconnaissance de la parole de manière à offrir à l'utilisateur une possibilité d'interaction avec les jeux.
Patent CA-2346729-A1 (CA)
Inventor: VAN BROECK DIDIER
IPC: C07D211/64
Filed: 1999-10-04
Abstract: La présente invention concerne les composés de formule (I) sous forme racémique ou optiquement pure, leurs procédés d'obtention et les compositions pharmaceutiques en contenant. Ces composés sont des antagonistes sélectifs du récepteur NK¿3?.
Patent CA-2349412-A1 (CA)
Title: Single crystal vane segment and method of manufacture
Inventor: FRASIER DONALD J
IPC: C22C1/02
Filed: 1999-11-04
Abstract: The present invention contemplates a multi-airfoil vane segment (50) produced as a single crystal casting from a rhenium containing directionally solidified alloy. The single crystal casting containing grain boundary strengtheners.
Patent CA-2353288-A1 (CA)
Title: Skin of an airplane door
Inventor: KLOCKOW GUNTHER
IPC: B64C1/14
Filed: 2001-07-19
Abstract: The invention relates to a skin of an airplane door, which conforms to the surrounding surface contour of the fuselage, and which during the flight is exposed to a pressure load direction. It is an object of the invention to provide the skin of an airplane door with a clearly smaller dimension for the purpose of a light construction, thus permitting a weight reduction of the door. The object is achieved in that the skin is performed against the pressure load direction and connected with supports of a door frame. During flight at cruising altitude, the internal fuselage pressures deform the skin away from a predetermined shape so as to conform the exterior of the skin with adjacent exterior surfaces of the fuselage, thereby minimizing flow resistance.
Patent CA-2354610-A1 (CA)
Title: Human secretory phospholipase a2
Inventor: HANASAKI KOHJI
IPC: G01N33/573
Filed: 1999-12-07
Abstract: A gene encoding human secretory phospholipase A2 (PLA2); an expression vector having this gene; and a transformant having this expression vector transferred thereinto. The PLA2 protein can be produced by culturing this transformant.
Patent CA-2356777-A1 (CA)
Title: Pseudopeptide compounds having an inhibiting activity with respect to paths activated by proteins with active tyrosine kinase activity and pharmaceutical compositions containing same
Inventor: VIDAL MICHEL
IPC: C07K5/08
Filed: 1999-12-24
Abstract: The invention concerns a compound corresponding to general formula (I) wherein, in particular: R2 represents a phenylmethyl or naphthylmethyl or cyclohexylmethyl radical, 2- and 3-pyridinylmethyl, substituted on the cycle in meta or para position by an acid group or an alkyl radical of the type (CH2)n (with n = 3 or 4) substituted in terminal position by an acid group; and R3 represents a hydrogen group or a linear or branched C1-C4 alkyl or alkylcycloalkyl with a C3-C6 cycloalkyl. The invention also concerns the use of a compound of general formula (I) for preparing a pharmaceutical composition for treating diseases related to proliferative processes, cancers and/or metastases.
Patent CA-2359449-A1 (CA)
Title: Phenanthridine-n-oxides with pde-iv inhibiting activity
Inventor: GUTTERER BEATE
IPC: A61P43/00
Filed: 2000-01-13
Abstract: The N-oxides of the compounds of formula (I), in which R1, R2, R3, R31, R4, R5, R51 and R6 have the meanings indicated in the description, are novel active bronchial therapeutics.
Patent CA-2362393-A1 (CA)
Inventor: ROOBOL CHRISTIAAN
IPC: H04L12/56
Filed: 2000-02-11
Abstract: La présente invention améliore la fiabilité d'une transmission de données du fait que ce sont plusieurs unités de données dans un groupe ou un bloc qui sont analysées plutôt que des unités de données individuelles. Par exemple, au moment où un émetteur désire envoyer, ou bien a besoin d'envoyer, une requête d'appel sélectif à un récepteur, il peut y avoir plus d'une unité de données disponible pour l'envoi sous forme de groupe. Tous les champs d'appels sélectifs des unités de données faisant partie de ce groupe sont déterminés pour indiquer une requête d'appel sélectif. Lorsque le récepteur reçoit ce groupe d'unités de données, il envoie les informations d'état demandées à l'émetteur si le champ d'appel sélectif d'au moins une des unités de données reçue faisant partie du groupe indique une requête d'appel sélectif. En outre, si le champ d'appel sélectif de plusieurs unités de données faisant partie du groupe indique une requête d'appel sélectif, le récepteur n'envoie qu'une seule fois les informations d'état demandées.
Patent CA-2363659-A1 (CA)
Title: Transformateur piezoelectrique
Inventor: KANAYAMA KOUICHI
IPC: H01L41/107
Filed: 2000-02-16
Abstract: Un transformateur piézoélectrique comporte au moins deux substrats piézoélectriques plats (1, 2, 3) possédant chacun des surfaces principales opposées pourvues d'électrodes, lesdits substrats piézoélectriques étant assemblés à l'aide d'au moins deux écarteurs (4a, 4b, 4c, 4d) qui sont disposés entre lesdits substrats. Le premier substrat piézoélectrique (1) et le second substrat piézoélectrique (2) sont agencés de manière qu'un espace soit créé entre eux par au moins deux écarteurs (4a, 4b) et que la face inférieure du premier substrat piézoélectrique (1) soit opposée à la face supérieure du second substrat piézoélectrique (2). Une section d'entrée est formée sur l'un des deux substrats piézoélectriques (1, 2) et une section de sortie est formée sur l'autre substrat piézoélectrique. Ce transformateur piézoélectrique peut délivrer une puissance de sortie élevée.
Patent CA-2363950-A1 (CA)
Inventor: PIKE ROBERT
IPC: H01R13/658
Filed: 2000-02-17
Abstract: An electrical plug connector (1) includes two separate modules, one of which is an electrical contact module (2) that plugs into the housing (4), and the other of which is a printed circuit board (3) that is secured to the housing upon insertion. The contacts (10) of the electrical contact module being arranged to engage terminals (29) of the printed circuit board upon insertion of the respective modules into the connector housing. The plug connector housing includes a pair of latch arms (17) and a guide slot (14), the contact module and the circuit board, each being arranged to be guided by the guide slot during insertion into the housing and to capture one of the latch arms upon completion of insertion. To enable the plug connector to be keyed to a specific receptacle, the plug includes polarization keys (8), and the receptacle includes corresponding slots whose dimensions and configuration or position serve to key the plug to the receptacle. In addition, the receptacle includes a filter block that snaps into the receptacle housing and surrounds the contacts to provide EMI filtering.
Patent CA-2364513-A1 (CA)
Title: Trailing arm suspension with anti-creep automatic reset
Inventor: THOMAS PERRY W
IPC: B60G17/005
Filed: 2000-02-22
Abstract: A trailing arm suspension (10) with a height control valve (70) in combination with an anti-creep device (12) having an automatic reset mechanism (90) that pressurizes the air spring of the trailing arm suspension until the rotatable arm (60) of the anti-creep device (12) is free to rotate from an extended position to a retracted position, even if the ride height is set too low. The automatic reset mechanism (90) adjusts the trailer height to prevent the binding of the trailing arm suspension and the anti-creep device when the height control valve (70) is improperly adjusted.
Patent CA-2364611-A1 (CA)
Inventor: NIRCHIO PETER C
IPC: C07C317/14
Filed: 2000-03-16
Abstract: L'invention concerne des composés de formule (I). R?1¿, R?2¿, R?3¿, R?4¿ et R?5¿ représentent de manière indépendante hydrogène, chlore, brome, fluor, iode, alcoxy C¿1?-C¿3? substitué ou non substitué, linéaire ou ramifié, thioalcoxy C¿1?-C¿3 ?substitué ou non substitué, linéaire ou ramifié, alkyle C¿1?-C¿8? substitué ou non substitué, linéaire ou ramifié, hydroxyle, thiole, -CN, -CF¿3?, -OCF¿3?, -NO¿2?, acétyle, ou NR?6¿R?7¿; R?6¿ et R?7¿ représentent de manière indépendante hydrogène, méthyle, ou éthyle; et X représente iode ou brome. Dans un autre mode de réalisation, l'invention concerne des dérivés sulfonés spécifiques de benzène éthynyle. Le sulfone d'alkynyle aryle, selon l'invention, sert de biocide, y compris, mais sans s'y limiter, de bactéricide, de fongicide et d'agents de préservation. L'invention concerne également un procédé de préparation de sulfone d'alkynyle aryle selon la formule (I), ledit procédé comprenant la mise en contact d'un sulfone d'alkynyle aryle avec N-iodosuccinamide ou N-bromosuccinamide, l'acétone et le nitrate d'argent afin de former le sulfone d'alkynyle aryle halogéné correspondant.
Patent CA-2364649-A1 (CA)
Title: Process for manufacturing a multi-layer packaging film
Inventor: MARBLER CLAUDE A
IPC: B32B38/04
Filed: 2001-12-07
Abstract: A process for manufacturing a multi-layer packaging film (10) for an easy-open form of packaging (20), having at least one line of perforations (18, 18') which are provided in a plastic surface layer of the packaging and serve as an aid for alignment of a tear line propagating in the packaging film (10) on tearing open the packaging, is such that the perforations (18, 18') are cut into a surface layer which is in the form of a film (14) and the said pre-cut film (14) is joined to the other layers (12) to make up a composite film (10).
Patent CA-2365421-A1 (CA)
Inventor: YUE HENRY
IPC: C12N15/09
Filed: 2000-04-06
Abstract: The invention provides human vesicle associated proteins (VEAS) and polynucleotides which identify and encode VEAS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of VEAS.
Patent CA-2369401-A1 (CA)
Inventor: THIFAULT DOMINIQUE
IPC: D21F5/18
Filed: 2002-01-28
Abstract: The device (10) and method are used for ventilating an offset pocket space (12) located in a drying section of a papermaking machine by injecting air from a heated dry air supply inlet (11). The offset pocket space (12) is situated between a set of three axially-parallel drying cylinders (20) over which consecutive ly runs a paper web (14). A first and a third of these cylinders (20) are vertically spaced from a second one. The paper web (14) is pressed against the first and the third cylinder (20) by a felt (16) which further runs around a felt roll (26) havi ng a rotation axis parallel to that of the cylinders (20). The felt roll (26) is disposed between the three cylinders (20) in an offset position which is closer to th e first cylinder (20) than the third cylinder (20).  The device (10) comprises a first air outlet (50) where a first air stream i s directed into a cleft (34) defined where the felt (16) rejoins the felt roll (26), an d a second air outlet (52) where a second air stream is directed in close proximity to the felt (16) at a location which is upstream of the cleft (34). The second air strea m is in a direction which is substantially opposite the running direction (R) of the felt (16). In use, the device (10) and the corresponding method allow the first air stream  to flow through the felt (16) and lift the paper web (14) away from the felt (1 6) so as to reach the offset pocket space (12). The second air stream creates an air curtain to lower the pressure in a zone between the first (50) and the secon d (52) air outlet, thereby establishing a zone of reduced air pressure in close proximity to the felt (16) at a location which is immediately upstream of the cleft (34).
Patent CA-2369960-A1 (CA)
Title: Water removal in purification of vinyl chloride
Inventor: SMEDING RALPH
IPC: C07C17/383
Filed: 2000-04-20
Abstract: Removal of water in a vinyl chloride monomer purification system is achieved through (1) providing a distillation column for separation of a liquid admixture of vinyl chloride, hydrogen chloride, and water into (a) an essentially pure vinyl chloride product stream and (b) a hydrogen chloride distillate stream; and (2) placing a drying system in fluid communication with the distillation column midsection at a connection point where the water is at sufficient concentration to provide a useful mass transfer flux of water from a withdrawn midsection stream into a drying agent.
Patent CA-2371388-A1 (CA)
Inventor: NEWNES WILLIAM R
IPC: B65G47/22
Filed: 2002-02-12
Abstract: An apparatus for repositioning a workpiece on a lugged conveyor, where the conveyor has lugs for carrying the workpiece spaced apart by a lug space in a downstream direction. The apparatus includes a sensor for detecting the position of the workpiece on the conveyor and relaying position information to a processor, at least one running element mountable in cooperation with the conveyor, a selectively actuable actuator cooperating with the processor for the selective actuation of the running element.
Patent CA-2372854-A1 (CA)
Title: Identification of candida albicans essential fungal specific genes and use thereof in antifungal drug discovery
Inventor: DAVISON JOHN
IPC: C12Q1/68
Filed: 2000-05-05
Abstract: The invention relates to the identification and disruption of essential fungal specific genes isolated in the yeast pathogen Candida albicans namely CaKRE5, CaALR1 and CaCDC24 and to the use thereof in antifungal diagnosis and as essential antifungal targets in a fungal species for antifungal drug discovery. More specifically, the invention relates to the CaKRE5, CaALR1 and CaCDC24 genes, to their use to screen for antifungal compounds and to the drugs identified by such.
Patent CA-2374091-A1 (CA)
Title: The combined use of triglycerides containing medium chain fatty acids and exogenous lipolytic enzymes as feed supplements
Inventor: DIERICK NOEL
IPC: A23K50/60
Filed: 2000-06-06
Abstract: The present invention relates to the use of triglycerides (TG) containing medium chain fatty acids (C4 to C12), combined with exogenous lipolytic enzymes (esterases or lipases) as a feed supplement for animals in order to prevent and/or alleviate the problems which are frequently met at this moment. This results in a marked improvement of the growth performances without the use of the classical, but contested, feed additives.
Patent CA-2374965-A1 (CA)
Inventor: SAWANO KIYOSHI
IPC: B22D11/06
Filed: 2001-05-17
Abstract: A ceramic plate for a side weir of a twin drum type continuous casting apparatus, characterized in that it contains 9 mass % or more of Al, has a bending strength at room temperature of 120 MP or more, a bending strength a t 1000.ordm.C of 65 MPa or more, a hardness (Hv) of 50 to 350, a fracture toughness KIC at 1000.ordm.C of 1 Mpa .bullet. m1/2 or more, a heat conductivity at a temperature of room temperature to 1000 .ordm. C of 8 W / (m .bullet. K) or less, an index of the resistance to thermal shock R' of 800 W  / m or more and an contact angle .theta. (wetting characteristics) with molten  steel of 120 ~ or more. The ceramic plate for a side weir can be used for casting molten stainless steel continuously for a long period of time.</SDOA B>
Patent CA-2376244-A1 (CA)
Inventor: BABIN DENIS L
IPC: B23P15/00
Filed: 2001-06-13
Abstract: Selon l'invention, un procédé de fabrication et d'assemblage rapides de systèmes de canaux chauffants consiste à fabriquer plusieurs plaques collectrices, buses d'injection et bouchons, et à ajouter des éléments chauffants aux plaques collectrices. Le procédé consiste également à percer des canaux d'écoulement dans les plaques collectrices, et à placer ces dernières ainsi que les buses d'injection et les bouchons en stock. Le procédé consiste ensuite à enregistrer des commandes indiquant des spécifications pour les systèmes de canaux chauffants, puis à retirer du stock les plaques collectrices, les buses d'injection et les bouchons répondant aux spécifications indiquées dans les commandes. Le procédé consiste enfin à percer des trous dans les plaques collectrices pour les bouchons, à des emplacements indiqués par les spécifications, à insérer les bouchons dans les trous percés des plaques collectrices, et à fixer les buses aux plaques collectrices dans l'alignement des bouchons.
Patent CA-2380376-A1 (CA)
Title: Imageable seamed belts having hot melt processable, thermosetting resin and conductive carbon filler adhesive between interlocking seaming members
Inventor: MANOS CHRISTOPHER P
IPC: F16G3/00
Filed: 2002-04-03
Abstract: A seamed flexible belt having a substrate, a seam having interlocking seam members, and an optional overcoat, wherein the interlocking seam members are held together by an adhesive having a resistive, hot-melt processible, thermosetting resin and carbon filler, for use in electrostatographic, contact electrostatic, digital and other like machines.
Patent CA-2382774-A1 (CA)
Inventor: TERRETT JONATHAN A
IPC: A61P17/02
Filed: 2000-05-25
Abstract: The present invention relates to novel anti-angiogenic proteins, related to thrombospondin. More specifically, isolated nucleic acid molecules are provided encoding human METH1 and METH2. METH1 and METH2 polypeptides are al so provided, as are vectors, host cells and recombinant methods for producing t he same. Also provided are diagnostic methods for the prognosis of cancer and therapeutic methods for treating individuals in need of an increased amount of METH1 and METH2. Also provided are methods for inhibiting angiogenesis using  METH1 or METH2.
Patent CA-2383310-A1 (CA)
Title: Device and method for absorbing and radiating heat in very small space by alternately pushing two fluids
Inventor: LIU MING-HWA
IPC: F28D15/06
Filed: 2002-04-25
Abstract: A heat absorbing and radiating device includes a driving unit having communicable first fluid outlets and fourth fluid inlets, a heat-exchange unit communicating at an end with third fluid outlets of the driving unit and at another end with an inlet end of a liquid-gas confluence unit, which communicates at an outlet end with an inlet end of a liquid-gas separation chamber, while the latter communicates at an outlet end with one of two second fluid inlets of the driving unit. The driving unit is provided therein with reciprocatingly movable magnets to alternately push first and second fluids into the heat-exchange unit before them enter the fluid-gas confluence unit, so that hot air is finally released from the liquid-gas separation chamber. Since radiating fins and cooling fan are omitted, the device has reduced volume for use with a heat source in a small space, such as a CPU of a portable computer.
Patent CA-2384529-A1 (CA)
Title: Automated analyzer
Inventor: LEWIS SCOTT C
IPC: G01N33/543
Filed: 1991-08-28
Abstract: An analyzer for performing automated assay testing. The analyzer includes a storage and conveyor system for conveying cuvettes to an incubation or processing conveyor, a storage and selection system for test sample containers, a storage and selection system for reagent containers, sample and reagent aspirating and dispensing probes, a serration system for separating bound from unbound tracer or labeled reagent, a detection system and date collection/processing system. All of the subunits of the machine are controlled by a central processing unit to coordinate the activity of all of the subunits of the analyzer. The analyzer is specifically suited for performing heterogeneous binding assay protocols, particularly immunoassays.
Patent CA-2385028-A1 (CA)
Inventor: MCADAMS JASON D
IPC: F23D14/10
Filed: 2001-07-19
Abstract: A burner arrangement includes a venturi cluster including a plu-rality of venturis arranged for parallel flow. The multi venturi arrangement uti-lizing pressurized fuel as the inducing fluid to induce a flow of air enables the provision of an ultra fuel lean premix of fuel and air. A central burner tube which extends outwardly beyond the delivery end of a primary burner tip and mounts a relatively small capacity nozzle at a substantial distance from the delivery end of the burner tip enabling the ultra fuel lean mixture to expand and slow down such that its linear speed does not exceed the flame speed of the mixture prior to by the flame of the spaced nozzle. A deflector may be positioned adjacent the nozzle to assist in stabilizing the flame after the expansion and slowing process has been completed.
Patent CA-2386591-A1 (CA)
Inventor: NICKS YANA M
IPC: A47L23/20
Filed: 2000-10-20
Abstract: The present invention relates to shoe bags useful in laundering processes, especially for laundering of shoes, particularly leather-containing shoes, such as athletic shoes. The shoe bags of the present invention are preferably used in combination with compositions for treating one or more shoes in need of treatment, and methods and articles of manufacture employing same to treat the shoes prior to and/or during and/or after washing the shoes for imparting a desired benefit to the shoes such as cleaning and/or conditioning and/or disinfecting and/or deodorizing.