baber/WOPTO huggingface dataset:
Patent EP-0371998-B2 (EP)
Inventor: ROBINSON RANDY R
IPC: C07K16/00
Filed: 1988-07-25
Granted: 1999-11-03
Abstract: cDNA genetic sequences, vehicles containing same as well as hosts transformed therewith, for the production of chimeric immunoglobulin molecules, functional fragments thereof and immunoglobulin derivatives exhibiting novel functional properties comprising human constant region modules and non-human variable region modules, or for class switching antibody molecules and/or chains.
Patent EP-0348366-B2 (EP)
Inventor: JOHANSSON HANS ERIK
IPC: D21H23/76
Filed: 1989-05-09
Granted: 2001-10-24
Abstract: A process for the production of paper by forming and dewatering a suspension of cellulose containing fibres, and optional fillers, on a wire. The forming and dewatering is carried out in the presence of a combination of an aluminum compound, a cationic retention agent and a polymeric silicic acid having a high specific surface area. The combination of substances improves dewatering and retention of fines and fillers.
Patent EP-0385465-B2 (EP)
Inventor: HETZENECKER HEINZ
IPC: B29C48/13
Filed: 1990-03-01
Granted: 1999-06-16
Abstract: A plastic pipeline, especially for sewage, having a smooth inner pipe and a corrugated outer pipe, connected thereto, which can be connected via sleeve joints to an identical or a different conventional, standardised pipe, the latter being a co-extruded or composite pipe which is broadened in its one end region into a pipe sleeve. <IMAGE>
Patent EP-0489837-B2 (EP)
Inventor: WAYNER ELIZABETH
IPC: C07K7/06
Filed: 1990-08-31
Granted: 2013-11-13
Abstract: The present invention relates to a method for inhibiting the adhesion of one cell to another comprising interfering with the interaction between the extracellular matrix receptor and its ligand. The invention is based upon the discovery that the  alpha 4 beta 1 extracellular matrix receptor promotes adhesion of lymphocytes to endothelial cells via attachment to a defined peptide sequence. Prior to the present invention, the ligand of the  alpha 4 beta 1 receptor had not been identified, nor had the function of the  alpha 4 beta 1 receptor in lymphocyte attachment been known. By preventing the interaction between the  alpha 4 beta 1 receptor and its ligands using antibodies or defined peptide sequences, the present invention enables, for the first time, specific intervention in the migration of lymphocytes through the vascular endothelium and into tissues. The present invention, therefore, has particular clinical utility in suppression of the immune response, in various specific embodiments of the invention, the adherence of lymphocytes to endothelium may be inhibited systemically, or may, alternatively, be localized to particular tissues or circumscribed areas. Accordingly, the present invention provides for treatment of diseases involving autoimmune responses as well as other chronic or relapsing activations of the immune system, including allergy, asthma, and chronic inflammatory skin conditions.
Patent EP-0827748-B2 (EP)
Inventor: MARTIS LEO
IPC: A61P7/08
Filed: 1993-12-10
Granted: 2006-08-02
Abstract: The solution contains as osmotic agents both dectrose and polypeptides. The polypeptides are synthetic and are 4 to 10 amino acids long.
Patent JP-S6226734-B2 (JP)
IPC: G06F11/10
Filed: 1982-06-25
Abstract: A data processing system provides a diagnostic circuit having a scan-out function, that includes error checking. A scan-out address check code is generated by a sending unit and another scan-out address check code is generated by a receiving unit. The scan-out address check codes are compared in the sending unit, and an error in the scan-out operation can be detected.
Patent JP-H089634-B2 (JP)
Inventor: STUEBER WERNER DR
IPC: G01N33/53
Filed: 1992-05-08
Abstract: Amidinophenylalanine derivatives of the formula I <IMAGE> the synthesis of these compounds, the use thereof and pharmaceutical compositions which contain these compounds are described.
Patent JP-H0439863-B2 (JP)
IPC: A61M60/843
Filed: 1986-05-20
Abstract: An apparatus for wrapping a balloon catheter such as an intra-aortic balloon catheter is disclosed. The wrapping apparatus comprises a housing having a channel which receives the balloon membrane of the intra-aortic balloon. The wrapping apparatus also includes a clutching means located in the channel for exerting a predetermined pressure on the balloon membrane to enable the balloon membrane to be wrapped as the wrapping apparatus is rotated relative to the balloon catheter. The clutching means also permits relatively free rotation of the balloon membrane within the wrapping apparatus after the balloon membrane has been wrapped.The clutching means can include a shoe and a biasing means for biasing the shoe towards the balloon membrane with a predetermined pressure while the balloon membrane is being wrapped, yet enable the balloon membrane to rotate relatively freely within the wrapping apparatus after the balloon membrane has been wrapped to a predetermined degree.The clutching means, alternatively, can include flexible vanes projecting inwardly within the channel such that the vanes contact the balloon membrane during wrapping and provide a predetermined pressure onto the balloon membrane which aids in wrapping yet permits the wrapped balloon membrane to rotate relatively freely within the wrapping apparatus.
Patent JP-2772219-B2 (JP)
IPC: B60R21/20
Filed: 1993-06-02
Granted: 1998-07-02
Abstract: An airbag assembly 20 includes an inflator 100, a coupling device 300, an airbag 400, a cover 500 and a reaction device 600. The inflator 100 is positioned to supply inflation fluid to the airbag 400. The coupling device 300, the airbag 400, and the cover 500 are coupled to the reaction device 600 with a minimum number of fastening elements 28. The airbag assembly 20 further comprises a heat shield 200 which cradles a rear portion of the inflator 100 and which is coupled to the reaction device 600. The heat shield 200 is coupled to the reaction device by the fastening elements 28.
Patent JP-H0714964-B2 (JP)
IPC: A61K6/884
Filed: 1984-06-29
Abstract: There is described a photopolymerizable composition which contains at least one olefinically unsaturated compound and a photosensitive catalyst containing a diketone plus 4-(N,N-dimethylamino)benzoic acid or lower alkyl ester thereof.
Patent JP-S598640-B2 (JP)
IPC: B66F9/18
Filed: 1976-12-03
Abstract: SLIDER/ROLLER SIDE SHIFTER FOR USE ON A FORKLIFT TRUCK A side shifter frame unit for mounting on a forklift carriage includes sliding bearing shoes disposed in notches formed on a lip of an upper bar of the carriage.  The sliding bearing shoes have a rear surface inclined at an angle steeper with respect to the horizontal than a front upper bar carriage lip surface so that a side shifting unit will not tend to "climb" when the unit is laterally displaced.  A bottom plate of the side shifter utilizes a rolling disc rotatably mounted within a housing for rolling contact with a lower bar of the carriage. The rotatably mounted disc has its axis of rotation directed inwardly and inclined to the face of the lower bar.  In one embodiment of the invention, a side shifter actuator is secured to a bracket which is demountably suspended from the upper bar.
Patent JP-3827476-B2 (JP)
IPC: A61F2/966
Filed: 1999-06-08
Granted: 2006-09-27
Abstract: A device for transporting an appliance to be implanted comprising a tube having a front end, formed with a side window adjacent its front end and inserted into the appliance to be implanted, and a wire inserted into the tube and inserted through the front end of the tube so as to extend along the side window of the tube, the wire taken out of said side window over which the appliance to be implanted is engaged, and then said wire is inserted again into the tube through the side window so as to engage and hold the appliance to be implanted between the wire and the tube;  characterized by that said tube comprises two tube elements each spaced apart and a connector for connecting both tube elements, said side window is formed between both tube elements.  <IMAGE>
Patent JP-H0138798-B2 (JP)
IPC: A61K39/00
Filed: 1987-07-10
Abstract: Processes are provided for the synthesis of the human T-antigenic determinant 2-acetamido-2-deo×y-3-O-(β-D-galactopyranosyl)-a-D-galactopyranoside containing an a-0-glycosidically linked bridging arm O-(CH<sub>2</sub>)<sub>n</sub>COR. The determinant is coupled to carrier molecules to form artificial T-antigens, and to insoluble supports to form T-immunoadsorbents. The artificial T-antigen is shown to elicit a delayed type hypersensitivity reaction as a diagnostic for the presence of cancer in humans.
Patent JP-S6313807-B2 (JP)
IPC: B29C45/26
Filed: 1981-10-30
Abstract: A hot sprue assembly is provided for controlling flow of molten material into the mold cavity of an injection molding machine. The hot sprue assembly is particularly designed for use with an injection molding machine for molding centrally apertured record discs, such as video information discs. The hot sprue assembly includes a hot sprue bushing cooperating with a generally conically-shaped dispersion head to define an open an relatively narrow annular gate through which molten material is injected into the mold cavity, and a central die plug within the mold .avity for cooperating with the dispersion head to mold a central aperture into the disc. Valving of the molten material through the gate is achieved by heating the sprue assembly to create a temperature differential which, during solidification of the material within the mold cavity, permits the material within the mold cavity to solidify up to the gate without substantial solidification of material within the sprue assembly. The gate is disposed at a plane recessed slightly from the general plane of the solidified disc to prevent any surface discontinuities arising by retraction of the sprue assembly when the mold cavity is opened from projecting above the general plane of the disc.
Patent JP-2563748-B2 (JP)
IPC: A61N1/39
Filed: 1993-07-28
Granted: 1996-12-18
Abstract: An atrial defibrillator (30) provides cardioverting electrical energy to the atria (16, 18) of a human heart (10) in need of cardioversion. The atrial defibrillator includes a first detector (50) for detecting ventricular activations of the heart, a second detector (54) for detecting atrial activity of the heart, and an atrial fibrillation detector (70) responsive to the second detector for determining when the atria of the heart are in need of cardioversion. The atrial defibrillator also includes a cardioverting stage (72, 74, 76) for applying the cardioverting electrical energy to the atria of the heart when the atria of the heart are in need of cardioversion and when the time between immediately successive ventricular activations is greater than a preselected minimum time interval. <IMAGE>
Patent JP-2886290-B2 (JP)
IPC: G01S5/14
Filed: 1990-08-06
Granted: 1999-04-26
Abstract: PURPOSE:To make position measurement achievable at both mobile and fixed radio stations by measuring a pseudo-propagation delay time from both these radio stations with two satellites. CONSTITUTION:First of all, an antenna part 1 of a user unit receives radio waves W11, W12 transmitted out of a ground station via satellites S1 and S2, transferring them to a receiving processor part 3. A clock part 2 genarates transmitting timing for radio waves W21, W22, transferring them to the receiving part 3 and a transmitting part 4 as well. The processor part 3 measures a pseudo-propagation delay time of the W11, W12 from a time difference between the W11, 12 and the radio waves W21, 22. Likewise even in the ground station, the propagation delay time of these W21, 22 is measured. Next, on the basis of relations - distance between a user and a satellite, distance between a ground station and the satellite, a relationship between clock offset and pseudo-propagation delay time, a position is found out of a position measuring processor part of the ground station and the under unit. With this constitution, position measurement and communication service are performable at the same time.
Patent JP-H047181-B2 (JP)
IPC: A22C21/00
Filed: 1983-11-18
Abstract: The invention relates to a method and apparatus for dividing a slaughtered bird into a front half 31 and a back half 28, the body 12, prior to and during the cutting operation, being brought into a position wherein the legs are positioned in front of the rest of the body while, prior to and during the cutting operation, the edge portion 26, forming the boundary with the breast, of the opening 27 present between the legs, is pulled downwards, the body being subsequently divided into two halves starting just above said edge portion 26.
Patent JP-2603309-B2 (JP)
IPC: C08K5/00
Filed: 1988-09-14
Granted: 1997-04-23
Abstract: An olefin polymer composition having improved resistance to deterioration in the presence of chlorinated and nonchlorinated water and having improved resistance to temperatures of 0 DEG C to 100 DEG C, comprises a blend of:   (a) 93 to 99.5 percent by weight of an isotactic polymer of an alpha olefin of 2 to 6 carbon atoms; (b) 0.05 to 0.50 percent by weight of a hindered amine UV stabilizer;   (c) 0.05 to 1.1 by weight of a hindered phenolic thermal stabilizer having a molecular weight above 530;   (d) 0 to 0.5 percent by weight of a nucleating agent;   (e) 0 to 4 percent by weight of a pigment;   (f) 0 to 3.0 percent by weight of a filler; and   (g) >0 to 3.0 percent by weight of a chelating agent.   The composition can be used to fabricate pipes for carrying water and coatings for wire and cable.
Patent JP-2965799-B2 (JP)
IPC: C07K16/00
Filed: 1992-09-17
Granted: 1999-10-18
Abstract: The invention relates to a process for the fermentative production of amino acids, in which a strain of the genera Brevibacterium or Corynebacterium producing one or more amino acids is cultured in a nutrient medium and, at the end of the fermentation, the amino acid(s) is/are isolated from the culture fluid, which process is characterised in that following the strong growth phase the bacterial culture has less assimilable carbon source available than it could metabolise on account of the strain construction and of the amount of the otherwise necessary supplements provided in the nutrient medium.
Patent JP-2726047-B2 (JP)
IPC: H04R1/28
Filed: 1987-10-07
Granted: 1998-03-11
Abstract: Transducer consisting of an enclosure in the shape of a body of revolution about an axis, each end of which is closed off by a loudspeaker, the two loudspeakers, "active" and "passive", being mounted back-to-back on the axis of the enclosure. 
<??>To improve the performance of such a transducer and the quality of the sound transmission, the enclosure (6) is held vertically following its axis of revolution and the side wall (5) of the enclosure (6) consists of a flexible material, known per se, which is incapable of resonating with the fore or aft waves of the loudspeakers (1, 3). 
<IMAGE>
Patent JP-2627905-B2 (JP)
IPC: B01J2/08
Filed: 1987-10-07
Granted: 1997-07-09
Abstract: An apparatus and process for producing liquid droplets having a narrow size distribution. Thin liquid streams are forced under pressure through a plurality of orifices in an orifice plate, the largest of which orifices has a diameter not greater than about three times the diameter of the smallest of those orifices. Also the thin liquid streams are vibrated to cause the breakup of each stream into droplets having a narrow size distribution.
Patent JP-2793587-B2 (JP)
IPC: C07K16/00
Filed: 1987-10-08
Granted: 1998-09-03
Abstract: Receptors are disclosed that are antibodies that exhibit a binding affinity for an immune complex of a monoepitopic antigen and an antibody for such antigen that is substantially greater than the binding affinity for the monoepitopic antigen or the antibody for the monoepitopic antigen apart from the immune complex. Normally, the monoepitopic antigen has a molecular weight less than 1500 and is an organic compound. The antibodies of the present invention find use in a method for determining a monoepitopic antigen in a sample suspected of containing such antigen. The method comprises forming an immune sandwich complex comprising the monoepitopic antigen or an analog thereof, a first monoclonal antibody that binds to the monoepitopic antigen, and a second monoclonal antibody that is an antibody of the present invention and detecting the immune sandwich complex. Compositions of matter and kits for use in conducting an assay in accordance with the invention as well as methods for producing the above receptors are also disclosed.
Patent JP-2646316-B2 (JP)
IPC: C07C239/08
Filed: 1992-09-03
Granted: 1997-08-27
Abstract: HCFC blowing agents such as 141b which are stabilized with diethylhydroxylamine, 1,4-benzoquinone, or 2,6-di-t-butylbenzoquinone.
Patent JP-H0461994-B2 (JP)
IPC: F15B13/042
Filed: 1988-10-26
Abstract: Pressure medium valve having a valve piston located in a valve housing for control of a main pressure medium flow through the valve by the aid of a pilot flow through a variable pilot flow restriction disposed in the valve piston, said pilot flow deriving from the main pressure medium flow and being controllable by means of a control pilot valve. To achieve temperature independent control without area increase in the pilot flow chambers is besides said restriction (17) in the pilot flow direction in front thereof arranged an additonal restriction between the valve piston (2) and the cylindrical wall (15) surrounding the valve piston of the valve housing, said restriction having the form of a peripheral clearance (11) of a substantially greater axial length than height.
Patent JP-H0678274-B2 (JP)
IPC: A61K31/235
Filed: 1988-11-04
Abstract: Compounds of the general formula 
<IMAGE>
 in which
 R<1> denotes hydroxyl, lower alkoxy, amino, mono- or di-lower alkylamino;
 R<2> denotes hydrogen, alkyl, alkoxy or halogen;
 R<3>, R<4>, R<5>, R<6>, R<1><1> and R<1><2> independently of one another denote hydrogen or lower alkyl;
 R<3> and R<5> together denote a methylene or hydroxymethylene group;
 R<7>, R<8>, R<9> and R<1><0> denote hydrogen or lower alkyl; or
 R<1><1> and R<1><2> together denote an oxo group or spirocyclo-lower alkyl; or R<1><1> denotes hydrogen and R<1><2> denotes hydroxyl or acetoxy; and one of the radicals R<1><3> and R<1><4> denotes hydrogen and the other denotes lower alkyl or trifluoromethyl,
 and physiologically tolerable salts of carboxylic acids of the formula I can be used as medicines, in particular for the treatment of neoplasias, acne and psoriasis. The novel compounds can be prepared by synthesis of the C(R<1><3>)=C(R<1><4>) double bond according to Wittig from an appropriate bicyclic and an appropriate monocyclic component and, if appropriate, subsequent modification of functional groups.
Patent JP-3322100-B2 (JP)
IPC: B05B5/053
Filed: 1995-11-09
Granted: 2002-09-09
Abstract: A rotary atomizing electrostatic coating apparatus having a rotating spray head, and a paint nozzle for feeding paint on the front surface of the spray head, in which the spray head is comprising a spray head main body made of an electrically insulating material, and a plurality of discharge electrodes having nearly band-form pattern extending outward approximately along the rear side shape of the spray head main body from the central side of the spray head main body with a mutual phase difference or extending symmetrically about the axis of rotation of the spray head main body. The plurality of discharge electrodes rotate together with the spray head main body, and the discharge current in the front side direction of the axis of rotation of the spray head is made uniform and increased, thereby enhancing the painting efficiency.
Patent JP-3143507-B2 (JP)
IPC: A61K38/00
Filed: 1991-12-12
Granted: 2001-03-07
Abstract: The process entails human transferrin being pasteurised in the presence of a complexing agent in solution, and the complexing agent with the bound iron being removed. 
<??>This transferrin can be used as pharmaceutical or growth factor.
Patent JP-3515259-B2 (JP)
IPC: B65B13/30
Filed: 1995-12-22
Granted: 2004-04-05
Abstract: A pneumatically powered strapping tool (10), which is modular, comprises a tensioning motor module (200), a sealing motor module (400), a sealing mechanism module (300), and a control valve module (500). The tensioning motor module (200) comprises a pneumatic tensioning motor arranged to coact with a tensioning mechanism (100) driven by such motor for tensioning two overlapped ends of a steel strap drawn from a supply and wrapped around a load. The sealing motor module (200) includes a pneumatic sealing motor, which is arranged to drive the sealing mechanism module (300) for sealing the overlapped ends to each other, after the overlapped ends have been tensioned. The control valve module (500) includes pneumatic control valves (510, 520) for controlling the respective pneumatic motors. The modules (200, 300, 400, 500) and the tensioning means (100) are adapted to be readily assembled and to be readily disassembled without requiring disassembly of any of the modules.
Patent JP-2500848-B2 (JP)
IPC: G01N33/49
Filed: 1993-12-15
Granted: 1996-05-29
Abstract: Improved methods for the determination of clotting times of fibrinogen, APTT and PT are provided. Surprising and unexpected accuracy is obtained by combining a backward-looking approach to determine a desired range of values over times T1 and T2, selected in accordance with predetermined percentages of the observed Vmax, thereby avoiding early false positives due to noise and other inhomogeneities from reagent sample mixing. Thereafter, a regression analysis is performed over the time period T1 and T2 and from the derived function, the coagulation time is determined by calculating the time associated with the predetermined percentage of Vmax.
Patent JP-2790377-B2 (JP)
IPC: C08F283/01
Filed: 1993-05-13
Granted: 1998-08-27
Abstract: Water blown, thermosetting unsaturated polyester-polyurethane hybrid foam compositions are formed by the reaction of an A side composition and a B side composition. The A side composition comprises a polyfunctional isocyanate compound and a free radical initiator. The B side composition comprises a mixture of: (i) an ethylenically unsaturated monomer solution having dissolved therein about 30-90 weight percent of a polyester polyol having at least one ethylenically unsaturated group per molecule which has predominantly hydroxyl end groups; (ii) an amine compound having two or more primary or secondary amine groups in an amount effective to react with the A side composition to form small urea domains finely dispersed within a continuous polyester-polyurethane hybrid phase; and (iii) about 25 to about 150 equivalents water based on 100 equivalents of active hydrogen in the B side. When the A and B side compositions are reacted, the composition will have a ratio of active NCO groups of the isocyanate to active NH groups of the amine compound of between about 10:1 and about 50:1, and an isocyanate index, NCO:(NH + OH + COOH + HOH), of between about 0.5 and about 2.0.
Patent JP-3391796-B2 (JP)
IPC: C07D417/14
Filed: 1995-06-06
Granted: 2003-03-31
Abstract: This invention relates to pyridone-carboxylic acid derivatives of the following formula or salts thereof: <CHEM>     wherein     R1 is a hydrogen atom, a halogen atom, etc.,   R2 is a carboxyl group etc.,   R3 is a hydrogen atom etc.,   A is a nitrogen atom or CH,   m is 1 or 2, and   Y is an eliminable group or a group having the following formula: <CHEM>     wherein     R4 is a hydrogen atom or a lower alkyl group,   Z is a hydrogen atom, a lower alkyl group, etc.,   R5 is a hydrogen atom, a lower alkyl group, etc.,   n is 0 or 1, and   p is 1, 2, 3 or 4   and to processes for the preparation of these compounds, and further to anti-tumor agents which contain the above compounds as effective ingredients.