baber/WOPTO huggingface dataset:
Patent CA-2434668-A1 (CA)
Title: Novel approach to design glycopeptides based on o-specific polysaccharide of shigella flexneri serotype 2a
Inventor: GRANDJEAN CYRILLE
IPC: A61K47/48
Filed: 2003-07-07
Abstract: As part of a program for the development of synthetic vaccines against the pathogen Shigella flexneri, the conformational behavior of the O-specific polysaccharide (O-SP) of S. flexneri 5a and of four related synthetic pentasaccharide fragments was studied with a combination of NMR and molecular modeling methods. The NMR conformational analysis based on 1H and 13C chemical shifts analysis, inter-residue distances evaluation a s well as one- and three-bond heteronuclear coupling constants measurements shows that the conformation of one of the four related pentasaccharides closely mimics the conformational features of the native O-SP in solution. Inhibition ELISA demonstrated that a protective monoclonal antibody specific for S. flexneri 5a shows a higher affinity for this pentasaccharide when compared with the others. A complete conformational search was carried out on the pentasaccharides using the CICADA algorithm interfaced with MM3 force field. Boltzman-averaged inter-residue distances and 3J C,H coupling constants were calculated for the different conformational families and compared to data obtained by NMR on all pentasaccharides. Experimental data are consiste nt with only one conformational family. From these informations, several models of the O-SP have been built with the molecular builder POLYS. The models in agreement with NMR data consist o f right-handed helices presenting the branched glucosyl residue toward the external surface of their cylinder.
Patent CA-2434865-A1 (CA)
Inventor: PETERSON WAYNE
IPC: E21B19/24
Filed: 2003-07-10
Abstract: An apparatus for use in setting production slips, includes a body having a pair of arms positioned on a common plane. The pair of arms are adapted to engage an upper peripheral edge of a casing bowl. The pair of arms being separated by a pipe receiving channel which extends in from a peripheral edge of the body between the pair of arms and is adapted to accommodate a pipe, while the pair of arms support the production slips. Gripping members are provided on the body. The gripping members enable the body to be gripped and pulled from the casing bowl in order to cause the production slips to fall by force of gravity and wedge the pipe in the casing bowl.
Patent CA-2435332-A1 (CA)
Title: System and method providing distributed welding architecture
Inventor: BLANKENSHIP GEORGE DARYL
IPC: G05B19/418
Filed: 2002-01-22
Abstract: A system and method provides a distributed welding architecture in accordanc e with the present invention. The system includes a welder (124, 126, 128) operatively coupled to a server and a network interface to enable a network architecture, the network architecture serving a network that communicates with at least one remote system (30, 140, 310, 806). The remote system (30, 140, 310, 806) includes at least one remote interface (70) to communicate wi th the network architecture, wherein the remote system (30, 140, 310, 806) accesses at least one HTTP socket to establish web communications with the welder (124, 126, 128) and loads at least one application from the welder (124, 126, 128). The remote system (30, 140, 310, 806) accesses at least one Welding Application socket via the at least one application to exchange information between the welder (124, 126, 128) and the remote system (30, 14 0, 310, 806), wherein the at least one application includes at least one of a weld configuration component (74), a weld monitoring component (78), and a weld control component (82) to interact with the distributed welding system.
Patent CA-2438868-A1 (CA)
Title: Modulators of kcnq potassium channels and use thereof in treating migraine and mechanistically related diseases
Inventor: DWORETZKY STEVEN I
IPC: A61P25/06
Filed: 2002-02-14
Abstract: Compounds which function as modulators, particularly, openers, of human KCNQ potassium channel proteins or polypeptides, particularly, central nervous system(CNS)-located KCNQ potassium channels, and heteromultimers thereof, an d their use in the treatment of migraine are provided by the present invention . One novel type of potassium channel polypeptide openers provided by the present invention is the fluorooxindole compounds, described for the first time as therapeutics for the treatment of migraine by preventing the asynchronous firing of neurons. Other KCNQ potassium channel opener compound s that are also useful in the treatments of the invention include 2,4- disubstituted pyrimidine-5-carboxamide derivatives. One or more of the compounds according to the present invention may be utilized alone, in combination, or in conjunction with other treatment modalities for reducing, ameliorating and/or alleviating migraine or diseases similar to, or mechanistically related to, migraine, e.g., cluster headache.
Patent CA-2439961-A1 (CA)
Inventor: CHEN ZHI
IPC: A61P31/04
Filed: 2002-03-22
Abstract: Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as "Zcytor16".
Patent CA-2443609-A1 (CA)
Title: Balloon catheter with two radiopaque markers on the balloon and method of manufacture
Inventor: SARGE JEFFREY A
IPC: A61F2/958
Filed: 2002-06-06
Abstract: A stent delivery device which includes a balloon catheter (10) having at least one radiopaque region or portion (20) on the balloon (16) which mark the end(s) of the stent mounted on the balloon (16) for delivery.
Patent CA-2446491-A1 (CA)
Title: Compositions including vitamin-based surfactants ad methods for using same
Inventor: CHADWICK RICHARD
IPC: C11D1/68
Filed: 2002-04-26
Abstract: Compositions for caring for contact lenses and eyes include a liquid aqueous medium and a vitamin derivative component present in an amount effective as a surfactant in the composition. The compositions can be used to clean, soak, re-wet and, with the inclusion of a disinfectant, disinfect contact lenses. In addition, the compositions are effective as artificial tears and eye wash solutions. Methods for contact lens care and eye care are also disclosed.
Patent CA-2447963-A1 (CA)
Title: System and method for life sciences discovery, design and development
Inventor: BAEK OCK KEE
IPC: G16B50/40
Filed: 2003-10-31
Abstract: A system and method of providing automation, data management and collaboration facilities between researchers and disciplines in a cost efficient and centrally managed and maintained manner for research programs in the life sciences disciplines and the like is provided. The system and method provides an end to end information technology system which allows researchers from multiple research disciplines, and in geographically diverse locations, to cooperate in research efforts. Management of large amounts of experimental and reference information is inherently provided to meet diverse requirements of the researchers and regulatory agencies, while appropriate security of the managed information is maintained.
Patent CA-2451226-A1 (CA)
Inventor: EDSTROM MATTHEW
IPC: B29C48/17
Filed: 2002-06-26
Abstract: L'invention concerne un procédé de préparation d'un pain de toilette comprenant des stries de plaquettes bien définies. Ce procédé consiste à extruder un pain de toilette présentant des plaquettes au moyen d'une extrudeuse dotée d'une barrière perforée à travers la section transversale de celle-ci, la barrière étant placée à une distance suffisante de l'araignée, de manière que des stries de plaquettes bien définies puissent être observées à l'oeil nu dans le pain fini. D'une manière générale, la barrière perforée est située à au moins environ 60 %, de préférence à au moins environ 70 %, de l'araignée, tel que mesuré à partir de l'araignée en direction de l'orifice de sortie conique de l'extrudeuse. Généralement, une longueur normalisée conique d'extrudeuse de l'araignée à l'orifice conique est comprise entre environ 483mm et environ 560mm.
Patent CA-2451624-A1 (CA)
Title: Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
Inventor: TROLLSAS OLOF MIKAEL
IPC: A61L24/08
Filed: 2002-06-14
Abstract: Crosslinkable compositions are provided that readily crosslinkin situ to provide biocompatible, nonimmunogenic crosslinked biomaterials. The compositions contain at least three biocompatible, nonimmunogenic components having reactive functional groups thereon, with the functional groups select ed so as to enable inter-reaction between the components, i.e., crosslinking. I n a preferred embodiment, a first component is polynucleophilic, a second component is polyelectrophilic, and at least one third component contains on e or more functional groups reactive with the nucleophilic moieties one the first or second component. At least one of the components is a polyfunctiona l hydrophilic polymer; the other components may also comprise hydrophilic polymers, or they may be low molecular weight, typically hydrophobic, crosslinkers. Methods for preparing and using the compositions are also provided. Exemplary uses include tissue augmentation, biologically active agent delivery, bioadhesion, and prevention of adhesions following surgery o r injury.
Patent CA-2453154-A1 (CA)
Title: Dispositif de rembourrage
Inventor: DELUCA DONALD A
IPC: B43K23/08
Filed: 2002-07-08
Abstract: La présente invention concerne d'une façon générale un dispositif de rembourrage qui est adapté pour retenir un milieu fluide de façon à obtenir un effet de rembourrage. Ce dispositif de rembourrage possède un élément de rembourrage qui possède une vessie déformable définissant une chambre de milieu et un milieu fluide, tel qu'un fluide, retenu dans cette chambre. Cet élément de rembourrage est adapté pour être monté sur un article de façon à offrir un effet de rembourrage à un utilisateur. Ce dispositif de rembourrage peut éventuellement posséder un élément de support de façon à offrir un effet de rembourrage additionnel. Cette invention concerne aussi un article rembourré qui possède une prise digitale ou un article manipulé par les doigts sur lequel ce dispositif de rembourrage est monté de façon à offrir à un utilisateur une prise digitale confortable. Cet article rembourré est formé de façon qu'il puisse s'adapter à la prise digitale de son utilisateur et que sa vessie gonflée puissent être déformée par les doigts ou le bout des doigts de son utilisateur.
Patent CA-2454971-A1 (CA)
Inventor: FRALEY LAWRENCE R
IPC: H05K1/11
Filed: 2004-01-09
Abstract: A multi-chip electronic package which utilizes an organic, laminate chip carrier and a plurality of semiconductor chips positioned on an upper surface of the carrier. The organic, laminate chip carrier is comprised of a plurality of conductive planes and dielectric layers and couples the chips to underlying conductors on the bottom surface thereof. The carrier may include a high-speed portion to assure high-frequency connection between the semiconductor chips and may also include an internal capacitor and/or thermally conductive member for enhanced operational capabilities.
Patent CA-2455720-A1 (CA)
Title: Above the motor bellows expansion member for a submersible pump
Inventor: MERRILL DAN A
IPC: F04D13/08
Filed: 2004-01-21
Abstract: A bellows comprises a first fixed end, a second fixed end, a first collapsible section and a second collapsible section. The first collapsible section is in communication with the first fixed end and has a first cross-sectional area. The second collapsible section is in communication with the second fixed end and has a second cross-sectional area. A third collapsible section is between the first collapsible section and the second collapsible section. A first coupling member is between the first collapsible section and the third collapsible section. A second coupling member is between the second collapsible section and the third collapsible section. A volume within the bellows is varied by movement of the first coupling member and the second coupling member towards one of the first fixed end and the second fixed end.
Patent CA-2457500-A1 (CA)
Title: Methods of determining the concentration of an analyte in a fluid test sample
Inventor: DENG YINGPING
IPC: G01N33/487
Filed: 2004-02-05
Abstract: A method of determining the concentration of an analyte in a fluid test sample that in- cludes providing an electrochemical sensor adapted to measure the analyte in the test sample. The test sample sufficiently covers a counter and working electrode of the electrochemical sensor. A first potential is applied between the counter and working electrodes for a first pre- determined time period and the current is measured and the time is recorded. After the first potential is removed or substantially reduced, a second potential is applied between the counter and working electrodes and the current is measured. The concentration of the analyte is determined in the test sample as a function of the current measured. An index is calculated and compared to at least one predetermined parameter to identify when a bias, if any, exceeds a threshold. An error signal or analyte concentration is displayed depending on the compari- son.
Patent CA-2458857-A1 (CA)
Title: Safety cap for fluid dispensing cartridges
Inventor: ANTAL SR KEITH E
IPC: B65D47/20
Filed: 2002-07-17
Abstract: A removable safety cap (10) for use with an ink cartridge or other fluid holding container having a nozzle (34) extending from the dispensing end. The safety cap (10) prevents the flow of ink out of the cartridge or, if ink escapes past the dispensing nozzle seal, prevents the flow of ink outside the cap (10). The cap (10) also enables the ink cartridge to be set upright with the dispensing end down without the need for a nest or fixture to help support the cartridge.
Patent CA-2459188-A1 (CA)
Title: Wellhead production blowout preventer
Inventor: LAM TONY M
IPC: E21B33/06
Filed: 2004-02-27
Abstract: The invention broadly provides a ram incorporating a thermoplastic seal for sealing in the horizontal bore of a wellhead production blowout preventer to close off the vertical bore of the well, the ram being adapted to seal at its front end against either a polish rod of a rod string, or against an adjacent ram. The invention also extends to a BOP including a pair of such rams, wherein, each ram includes (a) a body component with front and rear portions and ends, (b) a seal component with front and rear portions and ends, (c) the body component having an arcuate longitudinal outer surface for conforming with the horizontal bore surface, and having a cut-out in its front portion Which provides a seal support surface to support the seal component in both a vertical and horizontal direction, (d) the seal component having an arcuate longitudinal outer surface for conforming with the horizontal bore surface, and an inner surface which generally conforms to the seal support surface of the body component, the body component and seal components combining, in an assembled form, to form a full bore ram body, which when out of sealing engagement has the front end of the seal component protruding a horizontal distance d beyond the front end of the body component, (e) connectors for connecting the seal and body components while allowing the seal component, during sealing engagement, to be pressed against the seal support surface of the body component, and (f) the seal component providing a sealing surface formed of thermoplastic material around the arcuate outer surface for sealing against the horizontal bore. Thus, as the body component is advanced forwardly into a sealing engagement causing the front end of the seal component to contact either the adjacent ram or the polish rod to seal off the vertical bore, the seal component is pressed against the seal support surface of the body component such that the thermoplastic sealing surface is compressed outwardly to seal against the horizontal bore.
Patent CA-2459663-A1 (CA)
Title: Flavored coffee compositions and methods of making the same
Inventor: HARDESTY DOUGLAS CRAIG
IPC: A23F5/46
Filed: 2002-10-18
Abstract: The present invention relates to non-segregating flavored coffee compositions.  In particular, the present invention relates to novel flavored coffee compositions that minimize or inhibit the segregation and separation of constituent components, and the corresponding processes for making such compositions. The flavored coffee compositions herein are characterized as having a roast and ground, an instant coffee component, or mixtures thereof.  The roast and ground coffee component will have a moisture level in the range of from about 1 % to about 15 %, a particle density in the range of from about 0.1 g/cc to about 0.45 g/cc, and a mean particle size distribution in the range of from about 400 microns to about 1300 microns. The instant coffee components used herein will have a particle density in the range of from about 0.1 g/cc to about 0.8 g/cc, a mean particle size distribution in the range of from about 250 microns to about 2360 microns, and a moisture level in the range of from about 1 % to about 4.5 %. The flavored coffee composition further comprises a flavoring component with a moisture level in the range of from about 1 % to about 7 %, a particle density in the range of from about 0.1 g/cc to about 0.8 g/cc, and a mean particle size distribution in the range of from about 5 microns to about 150 microns. The ratio of coffee component particle size to flavor component particle size is in the range of from about 100:1 to about 5:1.
Patent CA-2460269-A1 (CA)
Title: Alphavirus replicon vector systems
Inventor: DRYGA SERGEY A
IPC: A61P37/04
Filed: 2002-09-06
Abstract: The present invention provides compositions useful in and methods for producing populations of infectious, replication-defective alphavirus replic on particles that contain no replication-competent alphavirus particles, as determined by passage on cells in culture. The compositions include helper a nd replicon nucleic acid molecules that can further reduce the predicted frequency for formation of replication-competent virus and can optimize manufacturing strategies and costs.
Patent CA-2464469-A1 (CA)
Inventor: GRANT EDWARD R
IPC: G01N21/65
Filed: 2002-10-22
Abstract: Pulp and/or paper samples are scanned with a Laser Raman Spectroscopic probe , utilizing Raman spectroscopic technology, to generate Raman spectroscopic images of all or selected ones of the constituents and/or contaminants contained in the sample, to compare the same with a library of Raman spectroscopic fingerprints of known constituents and/or contaminants, and to identify and communicate data on all or selected ones of the constituents and/or contaminants for purposes of controlling the paper making process and/or determination of the quality of the paper produced.
Patent CA-2465990-A1 (CA)
Title: Method for reducing a particulate material containing a metal, especially iron ore
Inventor: ZELLER SIEGFRIED
IPC: C21B13/06
Filed: 2002-08-28
Abstract: In a process for reducing iron-ore-containing particulate material in at least a two-stage process, reducing gas is conducted through at least two reaction zones consecutively arranged in series and formed by a moving particulate material and the particulate material passes through the reaction zones in reverse order to the reducing gas, with the particulate material being heated in the reaction zone arranged first for the particulate material and being reduced in the further reaction zone.   In order to achieve a maximum preheating temperature without any formation of magnetite, the reducing gas added to the first reaction zone is conditioned such that no or hardly any reduction takes place, although for the particulate material a preheating temperature within the fringe range of starting a reduction is achieved, whereby either the degree of oxidation of the reducing gas is increased or the temperature of the reducing gas is decreased or both measures are carried out jointly and whereby, in the reactor zone arranged second for the iron ore, a temperature level of at least about 600°C, preferably in the range of between 600 and 700°C, in particular of between 620 and 660°C, is adjusted and the iron-oxide-containing material is reduced to wuestite (Fig. 1).
Patent CA-2467476-A1 (CA)
Inventor: SCHOSTAREZ HEINRICH J
IPC: A61P25/28
Filed: 2002-11-19
Abstract: Publié sans précis
Patent CA-2468620-A1 (CA)
Title: Basecoat coating composition having low volatile organic content and composite coating prepared therefrom
Inventor: O'CALLAGHAN PATRICIA
IPC: C09D175/04
Filed: 2002-12-10
Abstract: The invention provides a thermosetting aqueous basecoat coating composition with a pigment to binder ratio of at least about 0.5 that includes a polyurethane polymer, an acrylic polymer, and a crosslinking component that is reactive with at least one of the polyurethane polymer and the acrylic polymer. The polyurethane polymer has a glass transition temperature of 0~C or less. The acrylic polymer has a glass transition temperature that is at least about 20~C higher than the glass transition temperature of polyurethane resin.  The invention further provides a composite coating on a substrate having as a basecoat layer a cured layer of the basecoat composition of the invention and having at least one clearcoat layer over the basecoat layer.
Patent CA-2470284-A1 (CA)
Title: Vehicle navigation system
Inventor: FUNAYOSE YUSUKE
IPC: G01C21/00
Filed: 2004-06-08
Abstract: To provide a navigation system capable of properly displaying direction guide information, which represents a target direction and the like, regardless of forward motion or backward motion. In step S1, the current position of a vehicle is calculated. In step S2, the traveling direction of the vehicle is sensed. In step S3, an operation mode is determined. If the operation mode is a "compass mode," the process goes to step S4, and the orientation of the traveling direction is calculated based on the current. position and the traveling direction. If the operation mode is a "NAVI mode," the process goes to step S5, and a target position T separately set is read. In step S6, a target direction is calculated based on the current position and the target position T. In step S7, whether the motion of the vehicle is forward or backward is determined. If the motion of the vehicle is backward, the process goes to step S8, and direction guide information is corrected by an angle equivalent to 180°.
Patent CA-2473517-A1 (CA)
Title: Vegetation pruning device
Inventor: STONES KEVIN
IPC: B27B17/00
Filed: 2004-07-13
Abstract: A vegetation pruning device (2) includes a pair (4,6) of pivotally coupled arms. A motor bracket (36) with a rotary output drive (34) provides drive to a cutting element (8) which is coupled to the rotary output drive (34). The cutting element (8) is arranged for cutting vegetation (44) presented thereto.
Patent CA-2476370-A1 (CA)
Inventor: LOGAN DEREK
IPC: E21B17/00
Filed: 2004-07-30
Abstract: A compact, robust, wear resistant, and high performance electrically insulating gap sub for use with borehole EM Telemetry is disclosed. In one embodiment, the gap sub may include an externally threaded mandrel separated from an internally threaded housing by a dielectric material. Additionally, some embodiments may include an external gap ring for separating the upper and lower electrical halves of the sub which offers structural support, acts as the primary external seal, and provides an abrasion resistant non-conductive length on the exterior. Some embodiments may include torsion bins to prevent the possible unscrewing of the dielectric filled threaded sections should the dielectric material become damaged or weakened.