baber/WOPTO huggingface dataset:
Patent CA-2871536-A1 (CA)
Inventor: BRUECKNER THORSTEN
IPC: G01N21/25
Filed: 2013-04-25
Abstract: The present invention relates to a method for determining the amount of a specific analyte by photometric assays, wherein the specific analyte in a sample reacts with an analyte specific reaction partner in a reaction mixture. At least two calibration curves are generating, the first calibration curve recorded at a first wavelength is optimized for low concentrations of the specific analyte thereby maximizing the lower detection limit and, the second calibration curve recorded at a second wavelength is optimized for high concentrations of the specific analyte thereby maximizing the upper detection limit. The optimized lower detection limit and the optimized upper detection limit results in an extended dynamic range.
Patent CA-2873720-A1 (CA)
Inventor: NG GORDON YIU KON
IPC: A61P35/00
Filed: 2013-05-08
Abstract: La présente invention concerne des hybrides d'anticorps monovalents. Dans des modes de réalisation spécifiques, il s'agit d'un hybride d'anticorps monovalent comprenant : un hybride polypeptidique de liaison d'antigène qui se lie de manière monovalente à un antigène ; et un hybride polypeptidique dimère de Fc comprenant un domaine CH3, ledit hybride comprenant deux polypeptides monomères de Fc, un polypeptide monomère de Fc étant fusionné à au moins un polypeptide provenant de l'hybride polypeptidique de liaison d'antigène. Les présentes molécules thérapeutiquement nouvelles comprennent des hybrides monovalents qui présentent une augmentation de la densité de liaison et de Bmax (liaison maximale à un rapport cible à anticorps de 1:1) à une cellule cible présentant ledit antigène comparativement à un hybride d'anticorps bivalent monospécifique correspondant présentant deux régions de liaison d'antigène. Des procédés de génération d'hybrides d'anticorps monovalents qui montrent une efficacité d'effecteur supérieure comparativement à l'hybride d'anticorps bivalent correspondant à des concentrations équimolaires sont décrits dans la description. Des procédés de génération d'hybrides d'anticorps monovalents qui inhibent de manière inattendue la croissance de cellules tumorales, qui peuvent être internalisés et qui montrent une plus grande efficacité comparativement à un hybride d'anticorps divalent à des concentrations de saturation équimolaires sont décrits dans la description. Des hybrides d'anticorps monovalents destinés au traitement de maladies exprimant HER2 sont décrits.
Patent CA-2874020-A1 (CA)
Inventor: HABRAKEN JAN
IPC: B65D83/06
Filed: 2013-07-18
Abstract: An exemplary aspect comprises a container apparatus comprising: (a) a housing forming a reservoir; (b) a cover configured to fit on the top of the housing, and comprising a first door; (c) a first divider having at least one point in contact with the inner surface of the housing; and (d) a second divider having at least one point in contact with the inner surface of the housing; wherein the first divider and the second divider divide the reservoir into three joined compartments: a first compartment between the first divider and an inner surface of the housing, a second compartment between the first divider and the second divider, and a third compartment between the second divider and an inner surface of the housing.
Patent CA-2874420-A1 (CA)
Inventor: DE LUCCHI OTTORINO
IPC: C07D413/12
Filed: 2014-02-11
Abstract: Object of the present invention is an improved process for the preparation of key intermediates for the synthesis of statins.
Patent CA-2876500-A1 (CA)
Inventor: BURKETT DAVID H
IPC: A61B17/00
Filed: 2013-06-28
Abstract: Intravascular devices, systems, and methods are disclosed. In some embodiments, side-loading electrical connectors for use with intravascular devices are provided. The side-loading electrical connector has at least one electrical contact configured to interface with an electrical connector of the intravascular device. A first connection piece of the side-loading electrical connector is movable relative to a second connection piece between an open position and a closed position, wherein in the open position an elongated opening is formed between the first and second connection pieces to facilitate insertion of the electrical connector between the first and second connection pieces in a direction transverse to a longitudinal axis of the intravascular device and wherein in the closed position the at least one electrical contact is electrically coupled to the at least one electrical connector received between the first and second connection pieces.
Patent CA-2877034-A1 (CA)
Inventor: EL-AHMAD YOUSSEF
IPC: C07D487/04
Filed: 2013-06-21
Abstract: The invention relates to novel pyrimidinone-based heterocyclic compounds which are parasite growth inhibitors, having the general formula (I) in which Y is a morpholine chosen from three bridged morpholines, L is a bond or a linker, n = 0 or 1 and R2 is a methyl group when n = 0 and a hydrogen atom when n = 1. Process for the preparation thereof and therapeutic use thereof.
Patent CA-2877294-A1 (CA)
Title: Carbon oxides removal
Inventor: THOMAS DAVID
IPC: C07C1/12
Filed: 2013-06-19
Abstract: A process for reducing the carbon oxide content in natural gas, by producing a carbon oxide containing natural gas from a geological formation through a natural gas delivery system; providing a reaction zone containing at least one catalyst suitable for hydrocarbon conversion in the natural gas delivery system; introducing hydrogen into the carbon oxide containing natural gas to form a reaction mixture; and passing the reaction mixture to the catalyst in the reaction zone to convert at least a portion of the carbon oxides in the natural gas to hydrocarbons.
Patent CA-2877516-A1 (CA)
Inventor: BUTTINI MANUEL
IPC: A61K39/395
Filed: 2013-06-18
Abstract: The present invention provides antibodies directed against C-terminal and central epitopes of ?ß that preferentially bind compact plaques relative to diffuse plaques. The invention also provides methods of treating patients to reduce or eliminate the presence of compact plaques of ?ß and associated symptoms. In one aspect, the present invention provides a method of treating a patient diagnosed with mid- or late-stage Alzheimer's disease, comprising administering to the patient an effective regime of an antibody that binds to an epitope within residues 12-43 of ?ß and preferentially binds compact plaques relative to diffuse plaques. In some cases, the patient has been diagnosed with mid-stage Alzheimer's disease. In some cases, the patient has been diagnosed with late-stage Alzheimer's disease.
Patent CA-2879712-A1 (CA)
Inventor: KENIRY JEFFREY
IPC: C25C3/34
Filed: 2013-05-15
Abstract: L'invention porte sur une cellule électrolytique pour la production de métaux des terres rares. La cellule électrolytique comprend une enceinte de cellule dotée d'un ou plusieurs canaux inclinés disposés dans un fond de l'enceinte de la cellule, le long duquel ou desquels canaux des métaux des terres rares en fusion produits dans la cellule électrolytique peuvent s'égoutter. Une ou plusieurs cathodes sont suspendus à l'intérieur de l'enceinte de cellule suivant un alignement sensiblement vertical avec ledit ou lesdits canaux. Les surfaces opposées respectives de ladite ou desdites cathodes sont inclinées vers le bas et vers l'extérieur en biais par rapport à la verticale. Une ou plusieurs paires d'anodes sont suspendues à l'intérieur de l'enceinte de cellule ; chaque anode de ladite ou desdites paires a une face en regard inclinée par rapport à la verticale et à distance suivant un alignement parallèle avec les surfaces inclinées opposées respectives de ladite ou desdites cathodes pour délimiter une distance anode-cathode pratiquement constante entre elles. La cellule électrolytique comprend également un puisard destiné à recevoir des métaux des terres rares en fusion provenant du canal, le puisard étant à distance et isolé de ladite ou desdites cathodes et de ladite ou desdites anodes. La séparation des métaux des terres rares en fusion de ladite ou desdites cathodes et de ladite ou desdites anodes empêche la réaction et/ou la contamination avec du carbone fugitif provenant de ladite ou desdites anodes ou une contre-réaction avec des dégagements gazeux.
Patent CA-2880116-A1 (CA)
Title: Bar of a support structure for a false ceiling and working process for working the bar
Inventor: CIPRIANI GIUSEPPE
IPC: E04B9/06
Filed: 2012-07-27
Abstract: The present disclosure relates to a bar of a support structure for a false ceiling and to a working process for working the bar. The bar has an elongated shape along a longitudinal direction (L) and includes at least two sheet metal portions (5, 6) located side by side or overlapping, in contact or adherent, the one with the other along said longitudinal direction (L). In the bar a transverse direction (T), extending transverse to, or intersecting, said longitudinal direction (L) is defined. At least one of the sheet metal portion (5, 6) has cuts (9) defining partially cut parts (10, 10A, 1 1, 11A ), wherein a partially cut part (10, 10A, 11, 11A ) of at least one of the sheet metal portions (5, 6) protrudes towards the other of said sheet metal portion (5, 6) to determine an interference of parts, and wherein the cuts (9) are arranged, are directed, or extend along said transverse direction (T).
Patent CA-2882806-A1 (CA)
Title: Polymer beads incorporating solid particulate material
Inventor: ZHAO WEIGUO
IPC: C08K3/10
Filed: 2013-08-28
Abstract: The present invention relates to polymer beads comprising a polymeric matrix and having a pitted surface, the polymeric matrix (i) comprising polymerised monomer residues of (a) at least one mono-ethylenically unsaturated monomer, and (b) at least one crosslinking monomer having at least two ethylenically unsaturated groups separated by at least 4 consecutive acyclic atoms, and (ii) having distributed therethrough solid particulate material and polymeric porogen.
Patent CA-2884367-A1 (CA)
Inventor: LAUKKANEN ANTTI
IPC: C12N5/00
Filed: 2013-09-24
Abstract: The present invention is related to methods and materials for culturing and transporting stem cells in a three-dimensional culture. The materials comprise cellulose nanofibrils in a form of three-dimensional discontinuous entities in a biocompatible hydrogel.
Patent CA-2884771-A1 (CA)
Inventor: MILLETT MARSHALL REED
IPC: H04N13/02
Filed: 2013-09-10
Abstract: Embodiments of the invention describe apparatuses, systems, and methods related to data capture of objects and/or an environment. In one embodiment, a user can capture time-indexed three-dimensional (3D) depth data using one or more portable data capture devices that can capture time indexed color images of a scene with depth information and location and orientation data. In addition, the data capture devices may be configured to captured a spherical view of the environment around the data capture device.
Patent CA-2885395-A1 (CA)
Inventor: BRESSON MATHIEU
IPC: B61L27/00
Filed: 2015-03-13
Abstract: This method comprises: the transmission, by a zone controller (50), of a request to reset the detection equipment (30) of a secondary detection system to the track, following the finding of an inconsistency on the state of occupancy of the zone (14B) between said secondary system and a primary detection system; receiving the reset request by the detection equipment (30); and resetting the detection equipment. At the end of the reset, the detection equipment verifies that no train has been detected as entering and / or leaving the zone between a time of emission by the zone controller of the request in reset and a end of reset time of the detection equipment.
Patent CA-2885534-A1 (CA)
Inventor: RANDALL GUY
IPC: B66C1/62
Filed: 2013-12-02
Abstract: A tool for making up and breaking out a drill string at an exit side of a bore. The tool includes a fixed vice and a moveable vice for torqueing a pipe joint, a roller assembly for threading and unthreading adjacent sections of pipe, and a retainer assembly to retain a detached pipe section. The components of the tool are mounted on a frame, which is pivotally connected to a hydraulic machine such as an excavator. Thus, the tool may be manipulated to remove and add sections of pipe to a drill string remote from the primary horizontal directional drill.
Patent CA-2887195-A1 (CA)
Inventor: ARBESMAN RAY
IPC: F16D69/04
Filed: 2009-10-06
Abstract: A modular brake pad is provided. The pad is made up of a brake backing plate and at least one pre-molded friction element. The friction element is releasably attached to the backing plate using an arrangement of guide rails. The friction element may also be locked to the plate by means of a releasable locking pin that extends through the plate into the friction element. An optional intermediary shim portion can also be provided on the friction element.
Patent CA-2890406-A1 (CA)
Inventor: YAMSHCHIKOV VLADIMIR
IPC: C07K14/18
Filed: 2013-11-06
Abstract: Mutations in the central monomer contact interface of the flavivirus envelope protein which modulate the infectivity of the flavivirus are made. The mutations decrease the ability of the envelope dimer protein to dissociate.
Patent CA-2891852-A1 (CA)
Inventor: PEDERSEN STEEN
IPC: B65B59/04
Filed: 2013-11-20
Abstract: The present invention concerns an apparatus for packing articles (2), wherein the packing is formed by at least one web material (4), wherein typically a plurality of individual juxtaposed runs of web material (4) and a number of more or less packed articles (2) are conveyed on the runs, wherein the apparatus includes first means which during packing of articles (2) join the web material (4) continuously in its longitudinal direction, as well as other means (3) for individual joints (5) and for separation in transverse direction of the web material (4), wherein the mentioned other means (3) are arranged on moving means adapted to move in the same direction and at the same speed as the web material (4) and the articles (2) being packed, called the X-axis, and in a direction against the web material (4) and the articles (2) arranged thereon, called the Y-axis.
Patent CA-2893045-A1 (CA)
Title: Insulated wire and motor
Inventor: OYA MAKOTO
IPC: H02K3/32
Filed: 2014-02-04
Abstract: Provided is an insulated electric wire comprising a conductor, an insulation layer including a foam heat-curable resin and which covers the outer circumferential surface of the conductor, and an outside non-foam insulation layer that covers the outer circumferential surface of the insulation layer. The thickness deformation rate of the insulation layer when a pressure of 1 MPa is applied at 25°C is 15%-50%. The pencil hardness of the outside non-foam insulation layer is at least 4H and the ratio between the insulation layer thickness and the outside non-foam insulation layer thickness is 20:80-80:20. Also provided is a motor having this insulated electric wire wound around a stator slot, in a state in which pressure is applied in the direction in which the outer diameter of the insulated electric wire decreases, and the thickness of the insulation layer is reduced.
Patent CA-2899612-A1 (CA)
Title: Lower spine brace
Inventor: BURKE STEVEN
IPC: A61F5/01
Filed: 2014-02-07
Abstract: A brace comprises one or more panels having an aperture or slit that is at least partially defined by a first portion and a second portion. Each panel can couple with a lateral support that is configured to wrap around a portion of a wearer's body. One or both of the first and second portions can comprise an arc that is configured to prevent a twisting of the panel when the brace is tightened around a wearer. One or both of the first and second portions can additionally or alternatively comprise a plurality of protrusions configured to interact with a portion of a lateral support to thereby assist in maintaining a vertical position of the lateral support with respect to the panel.
Patent CA-2899867-A1 (CA)
Title: Suralimentation a ecoulement prioritaire et pression limitee
Inventor: COOLIDGE GREGORY
IPC: F15B11/042
Filed: 2014-01-31
Abstract: L'invention concerne un ensemble distributeur hydraulique comprenant une admission ; une évacuation ; un compensateur de pression en amont de l'admission ; et un tiroir de distributeur de suralimentation à écoulement prioritaire et pression limitée mobile entre une première position et une seconde position et comprenant un corps de tiroir externe et un corps de tiroir interne. Le corps de tiroir externe comprend des encoches de mesure de blocage disposées de sorte que, dans la première position, le tiroir ferme la communication fluidique entre l'admission et le compensateur de pression, et de sorte que, dans la seconde position, le tiroir ouvre la communication fluidique entre l'admission et le compensateur de pression. Le corps de tiroir interne est mobile par rapport au corps de tiroir externe et est conçu pour ouvrir la communication fluidique entre l'admission et l'évacuation et pour contourner le compensateur. L'écoulement entre l'admission et le compensateur est un écoulement pilote réduit.
Patent CA-2900238-A1 (CA)
Inventor: CHANG WONSUK
IPC: C07H21/04
Filed: 2014-02-20
Abstract: The present invention relates to RNAi molecules, and compositions thereof, comprising a 2' internucleoside linkage connecting the nucleotide at position 1 and the nucleotide at position 2 at the 5' end of the antisense strand. Specifically, the invention relates to single- and double-stranded short interfering nucleic acid (siNA) molecules that are capable of mediating RNA interference comprising 5' modified nucleotides that comprise, among other potential modifications, a 2' internucleoside linkage. The invention further relates to 5' modified nucleotides used as reagents to generate the RNAi molecules of the invention and methods of using the disclosed RNAi molecules.
Patent CA-2901086-A1 (CA)
Title: Herbicidal compositions comprising flazasulfuron
Inventor: YAMADA RYU
IPC: A01P13/00
Filed: 2014-02-19
Abstract: Numerous herbicide compositions are currently being developed and used. However, there are cases when the compositions are not always adequate to control unwanted plants to be controlled such as weeds, and thus there is demand for the emergence of a highly active herbicide composition. Accordingly, provided are: a herbicide composition which includes flazasulfuron or a salt thereof, and at least one herbicidal compound selected from the group consisting of imazapic, hexazinone, mesotrione, and salts thereof; and a weed-control method using said composition.
Patent CA-2906137-A1 (CA)
Inventor: LAURENT ALAIN
IPC: C07D409/12
Filed: 2015-09-25
Abstract: The present invention relates to a novel family of covalent kinases inhibitors. Compounds of this class have been found to have inhibitory activity against members of the Tec kinase family, particularly ITK and/or RLK. The present inventions directed to a compound of Formula I (see formula I) or pharmaceutically acceptable salts, solvates, solvates of salts, stereoisomers, tautomers, isotopes, prodrugs, complexes or biologically active metabolites thereof, for use in therapy.
Patent CA-2908013-A1 (CA)
Title: Ceramic having a functional coating
Inventor: KRAMER GORDIAN
IPC: C04B41/85
Filed: 2014-03-28
Abstract: The invention relates to material composites composed of a ceramic substrate having a functional coating and to the production and use of said material composites.
Patent CA-2908327-A1 (CA)
Title: Mode application de kiosque pour systeme d'exploitation
Inventor: KUSCHER ALEXANDER FRIEDRICH
IPC: G06F9/44
Filed: 2014-05-08
Abstract: L'invention a trait à un procédé qui consiste à changer le mode d'un ordinateur pour passer d'un mode système d'exploitation à un mode kiosque, le mode kiosque fournissant une interface utilisateur qui correspond à une application Web et empêchant l'accès à toute autre application ou au système d'exploitation de l'ordinateur. Ledit ordinateur met automatiquement à jour l'application Web par le biais d'un réseau pendant qu'il fonctionne en mode kiosque, et met automatiquement à jour son système d'exploitation par le biais de ce réseau pendant qu'il fonctionne en mode kiosque. L'ordinateur relance automatiquement l'application Web en réponse à la détection de l'interruption de ladite application pendant qu'il fonctionne en mode kiosque.
Patent CA-2908399-A1 (CA)
Inventor: HAMAKUBO KATSUSHI
IPC: C09D4/02
Filed: 2014-03-27
Abstract: To provide a coating composition capable of forming an acrylic hard coat film that is excellent in adhesion to an antireflection film while having high scratch resistance, and an optical member having a hard coat film that is obtained by using the coating composition. A coating composition containing (A) an acrylate component and (B) zirconia, wherein a mass ratio (B)/(A) of (B) the zirconia to (A) the acrylate component is from 0.1 to 2.0, (A) the acrylate component contains the following components (a-1), (a-2) and (a-3), and a content ratio X of the component (a-1), a content ratio Y of the component (a-2) and a content ratio Z of the component (a-3) satisfies the following conditions (1) and (2), and an optical member having a hard coat film that is obtained by using the coating composition: (a-1): a polyfunctional acrylate compound having 3 or more acrylate groups in one molecule; (a-2): a dendritic aliphatic compound having an acrylate group at an end thereof and (a-3): an acrylate compound having 1 or 2 acrylate groups in one molecule; or a mixture of an acrylate compound having 1 or 2 acrylate groups in one molecule and an acrylate compound other than the components (a-1) and (a-2), the condition (1): in (A) the acrylate component, X is from 40 to 60% by mass, and a total of Y and Z is from 60 to 40% by mass, and the condition (2): in the total of Y and Z, Z is 0% by mass or more and less than 100%  by mass.
Patent CA-2909487-A1 (CA)
Inventor: RASBAND PAUL B
IPC: G06Q30/02
Filed: 2014-03-04
Abstract: Systems (100) and methods (800) for managing Mobile Point Of Sale ("MPOS") services of a retail store (102). The methods involve obtaining customer information specifying sensed activities and locations of customers (114) currently present in the retail store. Next, customer demands of the MPOS services are predicted based on the customer information. The MPOS services facilitate a purchase transaction by a customer for purchasing at least one item (116) offered for sale within the retail store. Thereafter, the MPOS services are managed based at least on the predicted customer demands of the MPOS services. Additionally, the MPOS services can be further managed based on employee information specifying sensed activities and locations of employees (150) within the retail store.
Patent CA-2910363-A1 (CA)
Title: Liquid collector mountable to an object for collecting liquid from the object
Inventor: LEPAGE DANIEL A
IPC: A61J1/05
Filed: 2013-04-23
Abstract: A sweat collector for wearing on a user's head to collect sweat from the user's head and prevent the collected sweat from running into the user's eyes. The sweat collector is at least partly made of nonabsorbent material. The sweat collector comprises a sweat-collecting recess between its inner and outer sides for collecting sweat. The sweat-collecting recess may be configured to retain the collected sweat by surface tension and adhesion. Other types of sweat collectors for collecting sweat from other body parts (e.g., a forearm) are considered. Other types of liquid collectors for collecting liquid other than sweat are considered (e.g., water on a user's head or other body part originating from a bath, pool or other external source; bottled liquid; etc.).