baber/WOPTO huggingface dataset:
Patent DE-602005023658-D1 (DE)
Inventor: SZCZEPEK WOJCIECH
IPC: C07D401/04
Filed: 2005-12-30
Abstract: An improved process for the preparation of imatinib base and its pharmaceutically acceptable acid addition salts by (a) reacting 2-methyl-5-nitroaniline with cyanamide in the presence of hydrochloric acid to obtain 1-(2-methyl-5-nitrophenyl)guanidine hydrochloride; (b) converting 1-(2-methyl-5-nitrophenyl)guanidine hydrochloride to 1-(2-methyl-5-nitrophenyl)guanidine nitrate; (c) condensing 3-acetylpyridine with N,N-dimethylformamide dimethyl acetal to obtain 3-(dimethylamino)-1-(3-pyridinyl)-prop-2-en-1-one; (d) reacting 3-(dimethylamino)-1-(3-pyridinyl)-prop-2-en-1-one with 1-(2-methyl-5-nitrophenyl)guanidine nitrate to obtain N-(5-nitro-2-methylphenyl)-4-(3-pyridinyl)-2-pyrimidineamine; (e) reducing N-(5-nitro-2-methylphenyl)-4-(3-pyridinyl)-2-pyrimidineamine using hydrazine in the presence of Raney nickel to obtain N-(5-amino-2-methylphenyl)-4-(3-pyridinyl)-2-pyrimidine-amine; (f) condensing N-(5-amino-2-methylphenyl)-4-(3-pyridinyl)-2-pyrimidine-amine with 4-chloromethylbenzoyl chloride in the presence of an inorganic base to obtain 4-(chloromethyl)-N-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)benzamide; and (g) condensing 4-(chloromethyl)-N-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)benzamide with an excess of N-methylpiperazine to obtain imatinib base; and adding water or a mixture of water and an organic solvent; and isolating said imatinib base. The process allows for using simple starting materials, while simultaneously avoiding a laborious isolation and purification of intermediates and the final product, thereby facilitating scale-up.
Patent DE-602005024371-D1 (DE)
Inventor: GRIES WILLI-KURT
IPC: G03F7/32
Filed: 2005-05-10
Abstract: The invention relates to a method of making a lithographic printing plate comprising the steps of providing a photopolymer printing plate precursor that is photopolymerizable upon absorption of light in the wavelength range from 300 to 700 nm, exposing said printing plate precursor with light in the range from 300 to 700 nm and processing said exposed precursor with an aqueous alkaline developer, characterized in that the alkaline developer comprises a polyethyleneoxide/polypropyleneoxide surfactant having a specific composition. The method leads to less depositions in the developing apparatus and on the processed printing plates and the developer used has an increased sedimentation stability.
Patent DE-602005025775-D1 (DE)
Inventor: COLGIN MARK A
IPC: G01N33/558
Filed: 2005-07-25
Abstract: An immunoassay test device is provided for detecting the presence of a molecule differentially associated with appendicitis in a sample from a patient suspected of having appendicitis. The device includes a first antibody specific to the molecule, a support for the first antibody, means for contacting the first antibody with the sample, and means for detecting binding of the first antibody with the molecule. MRP-8/14 and haptoglobin are examples of molecules differentially associated with appendicitis. In one embodiment, the device is in a flow-through format for testing blood samples.
Patent DE-602005025938-D1 (DE)
Inventor: OLSEN GERT
IPC: A63H19/30
Filed: 2005-11-10
Abstract: The present invention relates to a rail element, which has a connecting means ( 2 ) and is adapted to be connected to a second rail element ( 12 ) to form a toy railway. The rail element consists of a ramp element ( 1 ) having a ramp surface ( 3 ) which rises obliquely upwards from the base plane of the rail element, towards the connecting means ( 2 ). The rail element also has first and second border parts ( 8, 9 ) with first and second border surfaces ( 10, 11 ), which rise from the ramp surface ( 3 ) and are oriented towards the same. The distance between the border surfaces ( 10, 11 ) decreases towards the connecting means ( 2 ).
Patent DE-602005026676-D1 (DE)
Inventor: FUJIKAWA HARUHIKO
IPC: A61Q11/02
Filed: 2005-09-06
Abstract: A dental-plaque detection system and dental-plaque detection method which are excellent in the detection accuracy of dental plaques and also capable of improving the situation to stain sites other than dental plaques (such as interdental parts and gums) are provided. The dental-plaque detection system includes a dental-plaque staining agent, which contains at least one selected from yellow pigment of beni-koji, turmeric extracts, and curcumin; and a light-emitting apparatus, which outputs light having a wavelength within a range of 250 to 500 nm to an object in the oral cavity where the dental-plaque staining agent is attached. The dental-plaque detection method includes attaching a dental-plaque staining agent, which contains at least one selected from yellow pigment of beni-koji, turmeric extracts, and curcumin onto an object in the oral cavity; and thereafter irradiating light having a wavelength within a range of 250 to 500 mn onto the object.
Patent DE-602005027195-D1 (DE)
Inventor: WISE RICHARD S
IPC: H01L21/768
Filed: 2005-04-21
Abstract: A method of forming a wiring structure for an integrated circuit includes the steps of forming a plurality of features in a layer of dielectric material, and forming spacers on sidewalls of the features. Conductors are then formed in the features, being separated from the sidewalls by the spacers. The spacers are then removed, forming air gaps at the sidewalls so that the conductors are separated from the sidewalls by the air gaps. Dielectric layers above and below the conductors may be low-k dielectrics having a dielectric constant less than that of the dielectric between the conductors. A cross-section of each of the conductors has a bottom in contact with the a low-k dielectric layer, a top in contact with another low-k dielectric, and sides in contact only with the air gaps. The air gaps serve to reduce the intralevel capacitance.
Patent DE-602006002670-D1 (DE)
Inventor: TILLE THOMAS DR
IPC: G01N21/27
Filed: 2006-07-06
Abstract: A radiation source emits radiation in the form of pulses. During a pulse, a number of individual values are recorded in order to produce an average value. During the first radiation pulse the first individual value is compared with a predetermined threshold, and if the threshold is exceeded, an alarm signal is generates. An independent claim is included for a gas sensor apparatus.
Patent DE-602006007540-D1 (DE)
Inventor: BURGESS PATRICK E
IPC: G08G1/01
Filed: 2006-01-10
Abstract: This disclosure describes a Radio Frequency Identification (RFID) vehicle management system and method. For example, an RFID tag may be coupled with a particular vehicle and operable to store identifying information associated with the vehicle and to automatically communicate the identifying information to an RFID tag reader via a wireless communication. In another example, the method may include querying a first RFID tag coupled with a first vehicle for identifying information of the first vehicle. A second RFID tag coupled with a second vehicle for second identifying information of the second vehicle. The first identifying information and the second identifying information is dynamically communicated to a user.
Patent DE-602006008197-D1 (DE)
Inventor: AKIBA YOSHITAKA
IPC: B25C1/08
Filed: 2006-02-18
Abstract: A combustion-type power tool (1) includes a cylinder (10), a piston (11), a head (16), a combustion chamber frame (9), an ignition unit (18), a trigger (6), a control member. The combustion chamber frame is abuttable on the head to provide a combustion chamber in cooperation with the head and the piston. The trigger is operated by a user for driving the fastener into a workpiece. The control member detects that the combustion chamber has been provided and the trigger has been operated, and allows the ignition unit to ignite the combustible gas only when the control member detects that both the combustion chamber has been provided and the trigger has been operated.
Patent DE-602006011160-D1 (DE)
Inventor: SASSI ALDO
IPC: A63B24/00
Filed: 2006-09-12
Abstract: Eccentric cycle ergometer comprising an actual ergometer (1) and a bicycle (10), wherein said ergometer (1) transmits movement via a cogged belt (6) to a crown wheel (8) mounted in line with the rear hub of the bicycle, so that the transmission of the movement to the crown wheel (11) takes place via the chain (12) of the actual bicycle, which is wound on said crown wheel (12). The cycle ergometer also comprises a control panel (20) connected to a power unit (21), said control panel (20) being provided with a touch screen (22) whereby it is possible to set any one of the following operating modes: 
constant rate, constant power, constant torque.
Patent DE-602006011199-D1 (DE)
Inventor: WONG EMILE
IPC: C13B40/00
Filed: 2006-10-25
Abstract: The invention concerns a powdery compressible saccharose composition comprising at least 99.1 wt. % of saccharose, having a residual moisture content not more than 0.1 wt. % based on the composition total weight, said composition consisting of hollow particles, optionally agglomerated together in the form of granules.
Patent DE-602006013716-D1 (DE)
Inventor: CASSARINO GIANCARLO
IPC: D06C7/02
Filed: 2006-12-21
Abstract: A rubber belt comprising at least one layer of a plurality of tightly packed elastic yarns or fibers and at least one layer of silicone rubber. A method of manufacturing a rubber belt is also disclosed. The method comprises the steps of wrapping one or more elastic yarns or fibers onto a mandrel, where the one or more elastic yarns or fibers form one or more layers on the mandrel; adding a liquid high viscosity silicone rubber on top of the one or more layers; and heating the mandrel in order to polymerize the silicone rubber.
Patent DE-602006021324-D1 (DE)
Inventor: GROEN HERMAN
IPC: C12N5/16
Filed: 2006-08-23
Abstract: The invention provides a method of producing a stable lymphocyte culture and methods of producing monoclonal antibodies.
Patent DE-602007003358-D1 (DE)
Inventor: FUMALLE CHRISTIAN
IPC: E02D29/14
Filed: 2007-06-27
Abstract: The device has a transversal retaining pin (9) removably fixed in a hole (10) of a bridging element (2) transversal to a housing (8) of an articulation axle (7) to axially retain the axle in the housing against return force of a helicoidal compression spring. The helicoidal compression spring is prestressed in the housing between a bottom (8a) of the housing and an end of the axle. An independent claim is also included for a method of installing a bridging element.
Patent DE-602007007385-D1 (DE)
Inventor: ZHONG YU HUAWEI TECHN
IPC: H04L29/06
Filed: 2007-01-05
Abstract: A method for protecting a Digital Subscriber Line Access Multiplexer (DSLAM) includes: capturing specific protocol packets at an XDSL port by hardware of an XDSL single service board; and sending the captured specific protocol packets to a CPU of the XDSL single service board; determining whether the traffic amount of the specific protocol packets in a time unit exceeds a predefined threshold, if the traffic amount does not exceed the predefined threshold, submitting the specific protocol packets to a CPU of the host; otherwise stopping submitting the specific protocol packets to the CPU of the host. The method and the XDSL single service board provided by embodiments of the present invention need not manually set Media Access Control (MAC) address or maximum MAC address learning number for each XDSL port, which cuts down the maintenance workload, and on the other hand, reduces the loss of important protocol packets and lowers the load of the CPU.
Patent DE-602007008530-D1 (DE)
Inventor: RUEHL PHILLIP C
IPC: B62D21/09
Filed: 2007-02-01
Abstract: A frame rail assembly configured for use in various applications, including automotive vehicles. The frame rail assembly includes two rail portions. The rail portions include apertures each encompassed by a mounting boss. In addition, the frame rail includes spacers sized and configured to receive the mounting bosses in a snug fit to help with alignment. The spacers include at least one dimple in order to guide a mounting bolt though the apertures. The mounting bolt may be employed to hold the frame rail assembly together and attach other components to the frame rail assembly.
Patent DE-602007010594-D1 (DE)
Inventor: HILLAIRET CAROLINE
IPC: C08F4/642
Filed: 2007-03-07
Abstract: The present invention discloses active oligomerisation or polymerisation catalyst systems based on imino-quinolinol complexes.
Patent DE-602007012452-D1 (DE)
Inventor: ROCKEFELLER ALFRED G
IPC: H04N7/14
Filed: 2007-11-05
Abstract: A method for providing a videoconferencing service between two fourth generation wireless terminal types including cellular or wireless mobile and fixed terminals, said fixed terminals to include television receivers with a 4G wireless interface, each terminal employing a video camera, a microphone and loudspeaker. All terminal types will be rendered parametrically compatible by use of subscriber tables which identify called terminal parameters and which contain a class of service sequence which identifies the originating terminal's parameters wherein said class of service sequence is sent to the receiving terminal in an alternate caller ID along with selection characters which cause direct routing to the receiving terminal. The called subscriber may opt out of a video send mode by sending a “canned” video frame advising the caller that video is not available.
Patent DE-602007012957-D1 (DE)
Inventor: TECHEL ANJA
IPC: A01F29/09
Filed: 2007-03-29
Abstract: A cutting implement comprises a substrate (10) having a cutting edge (16), and plurality of hardfacing beads (22) deposited on the substrate (10) transverse to the edge (16) of said substrate.
Patent BR-132013001804-E2 (BR)
Title: alongador estrutural para expansão de cabine veicular
Inventor: BORTOLUZZI CARLOS ALBERTO BARCELLOS
IPC: B62D39/00
Filed: 2013-01-24
Abstract: "alongador estrutural para expansão de cabine veicular" o certificado de adição de invenção refere-se ao aperfeiçoamento em estrutura para cabine ou carroceria de um veículo automotor utilitário em substituição ao tem de série, visando expandir o seu espaço interno. o aperfeiçoamento em alongador estrutural para cabine e carroceria de veículo compreende: — um perfil sincronizador (1') que demarca o recorte para a abertura (a> da cabine e que é formado por uma banda de assentamento (10') na superfície externa da cabine, um sulco longitudinal (11') para guiar a substância de vedação, uma projeção com superfície indinada (12') voltada para fora, rebaixos transversais (13') para passagem dos elementos de fixação do perfil (1') na estrutura da cabine e uma borda ortogonal plana (14'> na ponta do perfil <1'); — uma cantoneira (15') de estruturação e acabamento que envolve a borda recortada da cabine e a superfície do perfil (1') que é voltada para o centro do recorte (a); — uma ponteira externa de revestimento <5) com seção transversal substancialmente em ali>, com uma borda livre (51) que contata a superfície inclinada (12') do perfil (1') e com a outra borda (52) dobrada para o interior, substancialmente em 9q0; — uma ponteira interna de acabamento (6) que contata a ponteira externa (5), também com seção transversal substancialmente em «12, com uma borda dobrada (61), substancialmente em 900, que contata a borda (14') da ponta do perfil (1') e outra borda dobrada (62), substancialmente em 900, que contata a borda dobrada (52) da ponteira externa (5); — um elemento de fechamento (3'), substancialmente plano, com cantoneiras extremas (31') que ladeiam as dobras (52) da ponteira externa (5) e as dobras (62) da ponteira interna <6).
Patent MD-955-G2 (MD)
Title: Hexa-ÕmuÚ-acetato(O,O')-ÕmuÚsubÕ3Ú-oxo-tris (N,N'-diethylnicotinamide)-diiron(III)cobalt(II) monohydrate having plant growing,vegetation and productivity regulation activity
Inventor: ŞTEFÎRŢĂ Anastasia
IPC: C07D213/82
Filed: 1997-07-29
Abstract: The invention relates to the new chemical compounds and may be used in the agriculture for plants growing, vegetation and productivity regulation.Summary of the invention consists in the fact that hexa-µ-acetato(O,O')-µ3-oxo-tris(N,N'-diethylnicotinamide)-diiron(III)cobalt(II) monohydrate, characterized by the formula [Fe2CoO(CH3COO)6 (DENA)3] . H2O, where DENA - N,N'-diethylnicotinamide, is used as biologic active compound for plants growing, vegetatioin and productivity regulation in the form of water solution having a concentration of 10-2...10-5 mass.%.r
Patent MD-1984-G2 (MD)
Title: Transport facility
Inventor: BEGANSCHII STANISLAV
IPC: B62D55/24
Filed: 1999-10-07
Abstract: The invention refers to the transport engineering industry, namely to the transportation facilities used in agriculture.The transport facility contains a frame, onto which there are placed the engine, the cab, the loading platform and the hydraulic pumps coupled with the engine, which are hydraulically joined with the hydraulic motors fixed onto the frame. Onto the outlet shafts of the hydraulic motors there are mounted pneumatic rollers provided with brakes and embraced by a collapsible caterpillar band. The hydraulic pumps are made with adjustable, axial pistons provided with a working fluid feed control unit and joined with the outlet shafts of the distributing gearbox, by means of which they are coupled with the engine. The hydraulic motors can be made planetary-rotative and provided with built-in reverses.The result consists in increasing the manoeuvrability of the transport facility.
Patent LU-88666-I2 (LU)
IPC: C07D211/90
Filed: 1979-06-12
Abstract: The present invention relates to new compounds having anti-hypertensive effect, which compounds are of the formulawherein R<sup>1</sup> is selected from the group consisting of -CH<sub>1</sub>, -C<sub>2</sub>H<sub>5</sub>, -CH<sub>2</sub>CH<sub>2</sub>OCH<sub>3</sub>, - CH<sub>2</sub>CH<sub>2</sub>OC<sub>2</sub>H<sub>5</sub>, and (CH<sub>2</sub>CH<sub>2</sub>O)<sub>2</sub>CH<sub>3</sub>, and R<sup>2</sup> is selected from the group consisting of -C<sub>2</sub>H<sub>3</sub>, -CH(CH<sub>3</sub>)<sub>2</sub>, -C(CH<sub>3</sub>)<sub>3</sub>, -CH(CH<sub>1</sub>)C<sub>2</sub>H<sub>3</sub>, -CH<sub>2</sub>CH<sub>2</sub>OCH(CH<sub>3</sub>)<sub>2</sub>, -CH(CH<sub>3</sub>)CH<sub>2</sub>OCH<sub>3</sub>, C(CH<sub>3</sub>)<sub>2</sub>CH<sub>2</sub>OCH<sub>3</sub>, -CH<sub>2</sub>C=CH, and -CH<sub>2</sub>C(CH<sub>3</sub>)=CH<sub>2</sub>, whereby R' and R are not the same, R' is selected from the group consisting of chloro and methoxy, and R' is selected from the group consisting of chloro, methyl, and methoxy, process for the preparation of said compounds, and pharmaceutical preparations containing said compounds.
Patent FR-16C0019-I2 (FR)
IPC: A61K45/00
Filed: 2016-05-17
Granted: 2017-12-08
Abstract: The invention relates a pharmaceutical composition comprising a combination of i the AT 1- antagonist valsartan or a pharmaceutically acceptable salt thereof and ii a NEP inhibitor or a pharmaceutically acceptable salt thereof and optionally a pharmaceutically acceptable carrier and to a method for the treatment or prevention of a condition or disease selected from the group consisting of hypertension, heart failure such as acute and chronic congestive heart failure, left ventricular dysfunction and hypertrophic cardiomyopathy, diabetic cardiac myopathy, supraventricular and ventricular arrhythmias, atrial fibrillation, atrial flutter, detrimental vascular remodeling, myocardial infarction and its sequelae, atherosclerosis, angina whether unstable or stable, renal insufficiency diabetic and non­-diabetic, heart failure, angina pectoris, diabetes, secondary aldosteronism, primary and secondary pulmonary hypertension, renal failure conditions, such as diabetic nephropathy, glomerulonephritis, scleroderma, glomerular sclerosis, proteinuria of primary renal disease, and also renal vascular hypertension, diabetic retinopathy, the management of other vascular disorders, such as migraine, peripheral vascular disease, Raynaud's disease, luminal hyperplasia, cognitive dysfunction such as Alzheimer's, glaucoma and stroke, comprising administering a therapeutically effective amount of the pharmaceutical composition to a mammal in need thereof.
Patent ES-2579161-R1 (ES)
Title: Nanofibras híbridas de aloe vera
Inventor: MONZON MAYOR MAXIMINA
IPC: B82Y5/00
Filed: 2016-03-08
Abstract: Abstract.#La presente invención proporciona nanofibras híbridas que comprenden una mezcla de los componentes de un gel de aloe vera y un polímero sintético seleccionado de poli-3-hidroxibutirato-co-3-hidroxivalerato (PHBV), ácido poli-L-láctico (PLLA) y polidioxanona (PDS), y donde el diámetro promedio de las nanofibras híbridas está comprendido entre 0,3 y 1,5 micras. Asimismo, la presente invención proporciona un método de fabricación de dichas nanofibras híbridas.#Las nanofibras híbridas de la invención pueden ser usadas en prótesis tubulares de reconexión nerviosa tras axotomía de nervios periféricos, en apósitos y suturas para mejorar la reinervación, y por tanto la recuperación sensitiva, de lesiones en órganos sensoriales como la piel (ej. quemaduras, úlceras, incisiones quirúrgicas, etc.) entre otros.
Patent CL-2008003617-S1 (CL)
Title: Perfil metalico de seccion definida y longitud indeterminada, especialmente disenado para uso en la construccion; el cual esta basicamente constituido por un cuerpo laminar central o pletina central que tiene adosados tanto en la superficie de la cara superior como inferior elementos laminares perpendiculares a este.(divisional de sol.2664-06)
Inventor: ANTONIO BENEDITO CARDOSO
Filed: 2008-12-04
Abstract: Perfil metálico.
Patent CL-2010000176-S1 (CL)
Title: Automovil constituido por un capo, en elevacion lateral, presenta una curvatura convexa inclinada en sentido descendente hacia el frente y en planta superior presenta una silueta trapecial isoscelica, cuya base mayor esta dirigida hacia atras con un trazado curvo concavo.
Inventor: NAOYA ISHIKURA
Filed: 2010-03-01
Abstract: automóvil.
Patent CL-2011001037-S1 (CL)
Title: Lateral de neumatico conformado cuatro aros concentricos, uno exterior con salientes triangulares, dos centrales lisos y uno interior formado por cuatro arcos circundantes de extremos biselados y una figura entre dos de ellos de forma triangular de lados convexos.
Inventor: SCHEIFELE KEVIN E
Filed: 2011-05-09
Abstract: Flanco de neumático.
Patent SI-0970236-T1 (SI)
Title: Fermentative production of valuable compounds on an industrial scale using chemically defined media
Inventor: DE LAAT WILHELMUS THEODORUS AN
IPC: C12N15/00
Filed: 1998-02-20
Abstract: The present invention describes the use of chemically defined media for the fermentative production of valuable compounds on an industrial scale. Microbial strains which are suitable for fermentation on an industrial scale using a chemically defined medium include fungal, yeast and bacterial strains. Suitable strains can be obtained as wild type strains or by screening and selection after mutagenic treatment or DNA transformation.