Patent GB-628315-A (GB)
Title: Improvements in or relating to dentifrice base and process of preparing the same
IPC: A61K8/04
Filed: 1944-09-19
Abstract: A free-flowing granular composition is prepared by moistening finely-divided particles of a polishing material having a particle size of 1 to 10 microns with an aqueous solution of a wetting agent, agglomerating the moistened material and drying the product, the wetting agent comprising a sulphonic acid having the formula <FORM:0628315/IV (c)/1> in which R is an alkyl group having 8-18 carbon atoms, Ar is an aromatic hydrocarbon nucleus, X is hydrogen, hydroxyl or halogen and m and n are whole numbers, or an alkali metal calcium or magnesium salt of such an acid.  Specified polishing materials are dicalcium phosphate dihydrate, tri-calcium phosphate, precipitated chalk, calcium sulphate in the form of its various hydrates, magnesium carbonate and the insoluble form of sodium metaphosphate.  Specified wetting agents are sodium lauryl sulphobenzoates, e.g. the metasulphobenzoate, or other sodium or potassium salts of octyl, decyl, dodecyl, tetradecyl, hexadecyl or octadecyl esters of sulphobenzoic and sulphosalicylic acids or mixtures thereof.  The Specification as open to inspection under Sect. 91 comprises also the employment, in addition or instead of the above specified wetting agents, of compounds of the general formula R1-SO3Y or R-O-SO3Y in which R1 is an alkylated aromatic residue of the formula R-Ar, R, and Ar being as above specified, and Y being hydrogen, an alkali metal, calcium or magnesium.  Specified compounds are sodium lauryl sulphate, alkylated benzene sulphonic acids in which the alkyl group may be decyl, dodecyl, or tetradecyl or their sodium salts, and sulphated octyl, decyl, dodecyl, tetradecyl, hexadecyl or octadecyl alcohols or mixtures thereof.  This subject-matter does not appear in the Specification as accepted.ALSO:A free-flowing dentifrice base is prepared by moistening finely divided particles of a dentifrice polishing material having a particle size of 1 to 10 microns with an aqueous solution of a wetting agent, agglomerating the moistened material and drying the product, the wetting agent comprising a sulphonic acid having the formula:  <FORM:0628315/VI/1> in which R is an alkyl group having 8-18 carbon atoms, Ar is an aromatic hydrocarbon nucleus, X is hydrogen, hydroxyl or halogen and m and n are whole numbers, or an alkali metal calcium or magnesium salt of such an acid.  The resulting dry granules should have a particle size of 10-35 mesh. Specified polishing materials are dicalcium phosphate dihydrate, tri-calcium phosphate, precipitated chalk, calcium sulphate in the form of its various hydrates, magnesium carbonate and the insoluble form of sodium metaphosphate.  Specified wetting agents are sodium lauryl sulphobenzoates, e.g., the meta-sulphobenzoate, or other sodium or potassium salts of octyl, decyl, dodecyl, tetradecyl, hexadecyl or octadecyl esters of sulphobenzoic and sulphosalicylic acids or mixtures thereof.  The Specification as open to inspection under Sect. 91 comprises also the employment, in addition or instead of the above specified wetting agents, of compounds of the general formula R1-SO3Y or R-O-SO3Y in which R1 is an alkylated aromatic residue of the formula R-Ar-R, and Ar being as above specified, and Y being hydrogen, an alkali metal, calcium or magnesium.  Specified compounds are sodium lauryl sulphate, alkylated benzene sulphonic acids in which the alkyl group may be decyl, dodecyl, or tetradecyl or their sodium salts, and sulphated octyl, decyl, dodecyl, tetradecyl, hexadecyl or octadecyl alcohols or mixtures thereof. This subject-matter does not appear in the Specification as accepted.