baber/WOPTO huggingface dataset:
Patent CA-2234894-C (CA)
Inventor: FISCHELL ROBERT E
IPC: A61F2/958
Filed: 1998-04-14
Granted: 2006-11-21
Abstract: The present invention is a balloon angioplasty catheter that combines a catheter shaft having increased pushability with an elongated, gradually tapered, highly flexible, lubricity coated, distal tip that is specifically designed to penetrate through a tight stenosis. The distal end of the tip is formed as a very thin-walled, tapered, frustrum of a cone that is capable of following a guide wire through even the most tortuous coronary arteries. The proximal end of the tip has a diameter that is equal to or slightly larger than the diameter of an angioplasty balloon that is wrapped around a catheter shaft at a distal section of the balloon angioplasty catheter. One embodiment of the invention includes a thin-walled tube lob at the proximal end of the distal tip which extends over the distal end of the angioplasty balloon. This design can prevent the distal end of the wrapped pre-deployed balloon from engaging the arterial wall as it is pushed through a tight stenosis. The balloon angioplasty catheter can be designed with the capability for either or both a rapid exchange or over-the-wire mode.
Patent CA-2236925-C (CA)
Inventor: CLEGG JAMES CHRISTOPHER STEPHE
IPC: A61K47/10
Filed: 1996-11-11
Granted: 2006-10-31
Abstract: A microparticle contains DNA coding for a polypeptide and oral administratio n of the microparticle leads to its expression. DNA coding for an immunogen is for stimulating antibody formation in a recipient and DNA coding for a non-immunogenic polypeptide is for gene therapy applications. DNA is incorporated into the microparticle withou t destruction of its function.
Patent CA-2237347-C (CA)
Title: Method for high speed spin winding of a coil about a continuous lamination core
Inventor: LAWRENCE GREG
IPC: H01F41/08
Filed: 1997-09-10
Granted: 2006-04-18
Abstract: A method for high speed spin winding a coil on a continuous lamination core. A two piece or hinged bobbin (26) having two flanges (30, 34) is placed around a leg of the transformer core (22) and snapped together. Both flanges include an outwardly facing surface which defines a concentric groove (46). One flange includes passages (54) for receiving printed circuit board terminating pins (58) which are installed prior to winding the coil. The other flange has a circumferential gear (30) located in its outwardly facing surface.      The core with bobbin and terminating pins installed is placed into a spin winding fixture. A bobbin bearing (62) having a bearing surface including a circumferential ridge (74) is placed adjacent the outwardly facing surfaces of the two flanges (30, 34) such that the circumferential ridges (74) are partially received within the concentric grooves (46) of the outwardly facing surfaces of the two flanges (30, 34). A wire feeder terminates the leading end of the coil wire on one of the terminating pins (58). A drive gear engages the circumferential gear (30) on the flange and rotates the bobbin at high speed drawing wire from the wire feeder. The wire feeder moves back and forth between the two flanges to uniformly wind the coil wire on the bobbin. The wire feeder terminates the trailing end of the coil wire on the other terminating pin and then cuts the wire off. The terminating pins are pressed further into the flange until the desired length for printed circuit board connection extends outwardly from the opposite side of the flange.
Patent CA-2238003-C (CA)
Title: Impedimetric detection system and method of production thereof
Inventor: ROSSAU RUDI
IPC: C12Q1/6825
Filed: 1996-11-29
Granted: 2005-02-22
Abstract: A sensor for identifying molecular structures within a sample solution is disclosed. The sensor comprises an insulating layer with a plurality of interspaced channels therein having essentially the same direction. Said channels have a bottom and at least two opposite side-walls along said direction. The channels furthermore have submicron dimensions. A metal coating is applied on one of said two opposite side-walls of essentially each channel and on top of the dielectric layer inbetween said channels thereby forming an impedimetric device with said sample solution within and between adjacent channels. Probes for specifically binding to said molecular structures can be applied, said probes being applied to either the insulating part of the channels (said bottom and the other side-wall of said channels), or to the surface of the electrodes or both, the insulating part of the channels and the surface of the electrodes. Furthermore, means are provided for applying a voltage on the metal coatings; and means for measuring the impedance inbetween the electrodes. Furthermore, a method of fabricating a sensor for identifying molecular structures within a sample solution is disclosed. This method comprises the steps of forming a plurality of interspaced channels in an insulating layer, said channels having essentially the same direction, said channels having a bottom and at least two opposite side-walls along said direction; depositing a metal layer on said insulating layer while aligning said insulating layer with respect to the metal deposition source such that the bottom of said canals a nd the side-walls of said canals along the deposition direction are shadowed and not covered by metal to thereby form an impedimetric device with said sample solution within and between adjacent channels; and applying probes for binding to said molecular structures, said probes being applied to either the insulating part of the channels (said bottom and the other side-wall of said channels), or to the surface of the electrodes or both, the insulating part of the channels and the surface of the electrodes, facing the deposition direction.
Patent CA-2239596-C (CA)
Inventor: OKADA HIDECHIKA
IPC: C07K16/28
Filed: 1996-12-17
Granted: 2007-07-31
Abstract: The present invention is directed to a sugar-chain--recognizing antibody which belongs to the IgM isotype and which recognizes Gg4Cer(Ga~.beta.1-3Ga~NAc.beta.1-4Ga~.beta.1-4G~.c.beta.Cer ) or GM2 which appears on HIV infected cells, as well as to a therapeutics for HIV diseases containing those IgMs.
Patent CA-2239839-C (CA)
Inventor: VAN ROMER EDWARD W
IPC: F16N31/00
Filed: 1998-06-08
Granted: 2004-11-16
Abstract: A foldable, portable containment is disclosed having ground sheeting which provides a floor section with a peripheral retaining wall made integral with the ground sheeting to contain hazardous spillage from a vehicle moved upon the floor section of the containment. Improved side bracing of the retaining wall is provided by rigid side braces having a rigid vertical leg, an inclined rigid leg which is affixed to a horizontal leg at a hinge. The free end of the horizontal leg abuts the vertical leg so that the inclined leg is anchored a fixed distance away from the retaining wall at an optimum bracing angle for reinforcement. The side braces may be made reversible so that they may be disposed on either an interior side of the retaining wall or an exterior side of the retaining wall to provide a trip profile. In either case, an anchor tab is provided to anchor the inclined leg at the hinge for optimum bracing effect.
Patent CA-2240144-C (CA)
Inventor: TREMBLAY RICHARD
IPC: E21D21/00
Filed: 1998-06-10
Granted: 2002-12-10
Abstract: A mine roof support system which includes a steel anchor rod and a threaded fastener.  The rod has a threaded end portion, and which is adapted for positioning in a bore hole so that the threaded end portion projects outwardly from a rock face.  The threaded fastener includes a body having a pair of opposing end portions and a bore which extends  along  its  central  axis.     Internal  threads complimentary to those on the rod are formed along part of the axial length of the bore, whereby the relative rotation of the fastener and rod moves the rod axially through the bore.   A cap member is detachably coupled to one end portion of the fastener covering part of the bore.  When coupled,  the cap member acts as a positive stop which limits relative movement of the rod axially through the fastener bore, and which when detached allows the fastener to run freely along the threaded portion of the rod.
Patent CA-2240681-C (CA)
Title: Creation and use of multiple gradients in electrophoresis in gel slabs and in capillaries
Inventor: RIGHETTI PIER GIORGIO
IPC: C12Q1/68
Filed: 1997-02-10
Granted: 2004-06-01
Abstract: The present invention refers to the use of multiple gradients (of chemical denutarants, thermal denaturants and of porosity of the gel matrix) for the separation of DNA fragments, amplified by PCR, normal or carrying point mutations, by zone electrophoresis on gel slabs or by capillary electrophoresis in presence of viscous polymer solutions (linear or branched). Such method can be extended to the analysis of mutations in proteins and to the optimization of, e.g., chiral separations in capillaries. The invention includes the use of binary gradients (chemical and porosity gradients or thermal and porosity gradients) or the simultaneous use of 3 gradients for point mutations having a very high melting point. In the case of capillary electrophoresis, the invention extends also to the use of batteries of capillaries, for the simultaneous analysis of a number of samples. Additionally, the invention includes the detection of DNA fragments (or of proteins and other analytes) by laser-induced fluorescence detection and the possibility of operating, in capillary electrophoresis, with mixed polymer solutions and with polyacrylamides obtained with monomers highly resistant to hydrolysis.
Patent CA-2243721-C (CA)
Inventor: KINGE RICHARD ARTHUR GEORGE
IPC: H01T15/00
Filed: 1998-07-20
Granted: 2006-12-05
Abstract: Conventional ignition systems have a first capacitor connected by a switch to the primary windings of a transformer. The secondary windings of the transformer are connected to an igniter via a cable. In the present invention, the secondary windings of the transformer are connected to a second capacitor via a rectifier circuit. The igniter is connected to the second capacitor by a cable that also has its own capacitance. In use, the combined charge on the second capacitor and the cable is gradually increased each time that the switch is closed and charge on the first capacitor is transferred to the transformer. The charge on the second capacitor and cable keeps increasing until it is sufficient to fire the igniter.
Patent CA-2246342-C (CA)
Inventor: BRAGDON CHARLES R
IPC: B29C43/16
Filed: 1997-02-11
Granted: 2008-04-22
Abstract: On décrit une prothèse médicale destinée à être implantée dans le corps, formée d'un polyéthylène à poids moléculaire très élevé et traité par rayonnement, et ne présentant pratiquement pas de radiaux libres détectables. Des prothèses préférées présentent une production réduite de particules à partir de la prothèse, lors de l'usure de celle-ci, et elles sont sensiblement résistantes à l'oxydation. On décrit également des procédés de fabrication de tels dispositifs, ainsi que le matériau utilisé pour leur fabrication.
Patent CA-2249820-C (CA)
Title: Fibre link superframe format
Inventor: GAUTHIER JOHN A
IPC: H04J3/16
Filed: 1998-10-06
Granted: 2004-08-17
Abstract: A serial optical link for transmission of payload data is utilised so as to permit transmission of information facility data unrelated to the payload data. A superframe is constructed at the transmission facility made up of a serial series of data frames. Each data frame consists of serially arranged words including a number of payload data words and a non-payload word. One non-payload word of the superframe has information facility data which provides a communication channel from the transmitting facility to the receiving facility for information unrelated to the communication of payload data. Another non-payload word has alarm and status facility data. The information facility data is stored in a FIFO buffer when received. If the FIFO buffer is within two words of being full, a full signal is incorporated in the next alarm and status facility data word which causes the receiving end to suspend sending information facility data words.
Patent CA-2256192-C (CA)
Inventor: RINGLIEN JAMES A
IPC: G06T7/40
Filed: 1998-12-15
Granted: 2006-04-04
Abstract: Infrared and visible light energies are directed through a container onto a CCD camera that is responsive to both the visible and infrared light energy.  Crossed polarizers are positioned on opposed sides of the container, and operate on the visible light energy in such a way as to block transmission of visible light to the camera in the absence of stress variations in the container, which alter polarization of the visible light energy traveling through the container. On the other hand, the polarizers have little or no effect on the infrared light energy, which creates a normally gray intensity of background light at the camera. In this way, incidence of visible light on the camera due to stress variations in the container appears as a bright signal against a normally gray background, while blockage of infrared light due to opaque variations in the container appears as a dark signal against the normally gray background.
Patent CA-2261264-C (CA)
Title: Process and composition for the antiparasitic treatment of the surroundings of animals
Inventor: YENNE SAMUEL PERRY
IPC: C05G3/60
Filed: 1997-07-17
Granted: 2004-03-23
Abstract: Control of darkling beetles by insecticides of 1-arylpyrazole type. Application to animal litter, especially for animal rearing. Mixtures of carbaryl and 1-arylpyrazoles.
Patent CA-2264222-C (CA)
Title: Valve stem with slidable, rotatable air-tight coupling for removably attachable devices
Inventor: LAIRD DAVID NORMAN
IPC: B60C29/06
Filed: 1999-02-26
Granted: 2004-08-17
Abstract: A tire valve stem having an integral pair of O-rings over which a pressure gauge or other device can be mounted by sliding a mating collar provided on the device over the O-rings. The O-rings provide an air-tight seal against the collar, and allow the device to rotate relative to the stem, either during or after mounting, to position the device anywhere within a 360° arc around the stem. The O-rings are located on either side of an orifice which extends through the valve stem, beneath the valve. Air passes from the pressurized valve stem, through the orifice, into an air-tight region between the O-rings, valve stem and collar. A port in the collar allows air to pass through the collar from the air-tight region into the device. A wide variety of devices equipped with collars capable of air-tight, slidable mounting over the O-rings can be provided, such as pressure transducers, pressure sensors, temperature gauges, temperature transducers, tem-perature sensors, or air conduits for coupling to remote equipment.      Any such device can quickly and easily be interchanged with a device previously mounted on the valve stem by sliding the previously mounted device's collar off the valve stem, then sliding another device's collar over the O-rings. For initial shipping purposes, a plain collar having no port and no device can be slidably mounted over the O-rings to prevent air passage beyond the air-tight region. The end user can quickly and easily replace the plain collar with a collar-equipped device suited to a particular application.
Patent CA-2266769-C (CA)
Title: Fluorite ceramic material
Inventor: CHRISTIANSEN NIELS
IPC: C04B35/50
Filed: 1999-03-24
Granted: 2006-02-07
Abstract: Ceramic material, having the general formula:      A x B y O2-.delta. wherein x <= 1, y <= 1 and -1 < .delta. < 1;      A is one or more metals selected from the group of Ti, Zr, Hf, Ce and Th or mixtures thereof;      B is at least two metals selected from group 2a, 3b and the lanthanide group of metals.
Patent CA-2267726-C (CA)
Inventor: FRANET ROGER
IPC: A01D43/10
Filed: 1999-04-15
Granted: 2003-08-19
Abstract: A mower-conditioner includes a header suspended from a mobile, main transverse frame by a pair of lower links, a single upper link and a pair of counterbalance springs. The upper link incorporates a threaded spindle to which a crank is coupled for changing the effective length of the upper link which extends between respective bearings carried by the main frame and the header and in this way pivots the header about the horizontal transverse axis defined by the bearings at the forward ends of the lower links so as to change the cutting angle of the cutter bar incorporated in the header. The upper link is mounted for sliding through the bearing carried by the header so as to permit the header to pivot upwardly about the axis in response to the cutter bar coming into contact with an obstacle during cutting operation. A coil compression spring is received on the upper link and biases it to its full effective length, the spring acting to cushion any impact of the cutter bar with an obstacle tending to tilt the header and acting to return the header to its original position once the obstacle is passed. Counterbalance springs are: coupled between opposite ends of the main frame and opposite sides of the header, the springs being substantially vertically oriented with their lower ends coupled close to the bearings at the fronts of the lower links which bearings are in turn displaced only a short horizontal distance from the center of gravity of the header so as to minimize the moments about the bearings due to the weight of the header and the force of the counterbalance springs.
Patent CA-2269204-C (CA)
Title: Anti-erbb2 antibodies
Inventor: FENDLY BRIAN M
IPC: C12N15/02
Filed: 1997-10-09
Granted: 2012-01-24
Abstract: Anti-ErbB2 antibodies are described which bind to an epitope in Domain 1 of ErbB2 and induce cell death via apoptosis. Various uses for these antibodies are also described.
Patent CA-2269863-C (CA)
Inventor: GENDRE FRANCOIS
IPC: C12Q1/689
Filed: 1997-10-27
Granted: 2005-04-05
Abstract: The invention concerns a method for detecting live microbiological contaminants in a food product sample which consists in detecting the presence of mRNA coding for the synthesis of a protein intervening in the synthesis of proteins by said contaminants, more particularly, mRNA coding for an elongation factor.
Patent CA-2275247-C (CA)
Inventor: NISHIOKA YOICHI
IPC: C08G75/0204
Filed: 1998-07-02
Granted: 2005-01-11
Abstract: L'invention concerne un agent ignifugeant exempt d'halogène, qui présente un point de fusion élevé et une faible volatilité et qui n'affecte pas les caractéristiques inhérentes aux résines. Ledit agent ignifugeant comprend un composé phénoxy-phosphazène réticulé produit par la réticulation d'un composé phosphazène avec des groupes de réticulation comme des groupes phénylènes, chaque groupe de réticulation étant placé entre les deux atomes d'oxygène restants après l'élimination des groupes phényles, et la proportion des groupes phényles du composé de phosphazène réticulé est de 50 à 99,9 % de la quantité totale des groupes phényles du composé phosphazène avant sa réticulation. Par ailleurs, l'invention concerne également des compositions de résine contenant ledit agent ignifugeant ainsi que des moulages formés desdites compositions de résine.
Patent CA-2276213-C (CA)
Title: Method of synthesizing phosphorothioate oligonucleotides
Inventor: RAVIKUMAR VASULINGA
IPC: C07H21/00
Filed: 1997-12-12
Granted: 2003-12-02
Abstract: This disclosure presents a method for the synthesis of phosphorothioate oligonucleotides using support-bound phosphoramidite intermediates.  Phosphoramidite intermediates useful in the execution of the method described are also disclosed.
Patent CA-2278552-C (CA)
Inventor: JAHNSSON MAGNUS
IPC: A61M15/00
Filed: 1998-01-29
Granted: 2007-04-17
Abstract: A generally flat elongated inhaler having a bend in its body at a predetermined distance from the outlet so as to ensure that the outlet is inserted sufficiently far into the mouth of the user and a method of ensuring that such an inhaler is inserted sufficiently far into the mouth of a user by providing a bend in the body.
Patent CA-2279554-C (CA)
Inventor: ALITALO KARI
IPC: A61K48/00
Filed: 1998-02-02
Granted: 2012-09-18
Abstract: Provided are purified and isolated VEGF-C polypeptides capable of binding to at least one of KDR receptor tyrosine kinase (VEGFR-2) and Flt4 receptor tyrosine kinase (VEGFR-3); analogs of such peptides that have VEGF-C-like or VEGF-like biological activities or that are VEGF or VEGF-C inhibitors;  polynucleotides encoding the polypeptides; vectors and host cells that embody the polynucleotides; pharmaceutical compositions and diagnostic reagents comprising the polypeptides; and methods of making and using the polypeptides.
Patent CA-2284656-C (CA)
Title: Aerosol dispensing device
Inventor: BACON RAYMOND JOHN
IPC: A61M15/00
Filed: 1998-03-16
Granted: 2007-05-22
Abstract: The dispenser (1) is for a medicament in an aerosol container (2), which is mounted in a body (3), within a sleeve (4) in a manner allowing air flow to pass the container, with the aerosol outlet tube (5) received in a socket (6) in a block (7) upstanding from the floor (8) of the body. The container is of the type which dispenses a measured dose on depression of the tube towards the container's body (9). The tube (5) is a gas tight seal in the socket (6). The block has a polyethylene tube (11) adhered into a side opening (12) of the block, in communication with the socket (6). The tube has a pair (13, 14) of kinks in it. Its end opposite from the block is adhered into a piston (15) at a throughbore (16). The piston is housed in a cylinder (17) formed in the body (3). To the outside of the cylinder is clipped an extension (18) of the body, having a mouthpiece (19) with an inhalation orifice (20). The arrangement provides an enlargement (21) in the bore (22) of the cylinder (17). The enlargement steps down in diameter to that of the (non-circular) mouthpiece, providing an abutment for a spring (23) acting on the piston and urging it in the direction of the block. Normally the tube is kinked (13, 14) by the action of the spring to such extent that it is obturated and acts as a valve (24). Thus when a dose is released into the socket (6), it is contained by the valve (24). On inhalation through the mounthpiece, the piston is drawn towards the mouthpiece against the action of the spring by the reduced pressure in the mouthpiece.
Patent CA-2285042-C (CA)
Title: Catheter assurant la communication fluidique avec l'intestin grele
Inventor: BENGMARK STIG
IPC: A61B1/005
Filed: 1998-02-02
Granted: 2006-10-17
Abstract: L'invention concerne une sonde assurant la communication fluidique avec l'intestin grêle. Cette sonde comprend un tube (10) qui est destiné à être inséré dans l'intestin grêle par l'estomac et est doté d'extrémités ouvertes (10A, 10B), proximale et distale. Ce tube a une tendance inhérente à former une spirale sur une longueur donnée à partir de l'extrémité distale. Cette sonde comprend également un fil de guidage (14) mobile dans le tube à partir de l'extrémité proximale pour redresser ladite longueur de telle manière qu'elle soit droite lors de son insertion dans l'estomac. Selon l'invention, le tube est doté, au moins sur la longueur donnée, d'une surface extérieure pileuse, dépolie, rugueuse, nervurée ou à ailettes.
Patent CA-2285066-C (CA)
Title: Nutritional formulations containing lacto-n-neotetraose
Inventor: PRIETO PEDRO A
IPC: A23L33/00
Filed: 1998-03-30
Granted: 2010-06-08
Abstract: A nutritional formulation containing an effective amount of Lacto-N-neoTetraose to simulate the growth and/or metabolic activity of Bifidobacterium is provided. A process of inhibiting bacterial infections including the step of feeding the nutritional composition to a subject is also provided.