baber/WOPTO huggingface dataset:
Patent ES-2065075-T3 (ES)
Inventor: CHARTRAIN PIERRE
IPC: F24C7/08
Filed: 1992-01-13
Granted: 1995-02-01
Abstract: The oven includes a cooking enclosure fitted with a movable door (3) hinged to the front face (2) of the said oven and equipped with a fastener (4) comprising a nose (5) and a notch (6). The fastener penetrates into an opening (9) in the front face in order to actuate a movable interlocking element (7). According to the invention, the interlocking element includes a pivoting wheel (20) positioned on a platen (14) fixed to the inner front face of the oven. The said wheel includes a first face (A) comprising two stop contacts (22 and 23), a safety interlock consisting of a locking finger (25) fixed to the second face (B) of the wheel and controlled by a safety pin (24) protruding through a slot (23') transversely to the first face (A) and intended, either to abut with the catch lock (26) of the platen, or to permit rotation of the wheel. Application to all closing devices. 
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Patent ES-2074297-T3 (ES)
Title: Dispositivo para activacion del sistema de columna vertebral humano.
Inventor: STOJANOVIC BRANISLAV
IPC: A61H7/00
Filed: 1992-03-23
Granted: 1995-09-01
Abstract: UN DISPOSITIVO PARA LA ACTIVACION DEL SISTEMA DE LA COLUMNA VERTEBRAL HUMANA. EL DISPOSITIVO COMPRENDE, AL MENOS, UN SEGMENTO (1) QUE TIENE UNA PLURALIDAD DE PROTUBERANCIAS (2) SEPARADAS POR RANURAS (3). LAS PROTUBERANCIAS (2) TIENEN EN SUS LATERALES UNA PLURALIDAD DE MUESCAS (4) CADA UNA, ESTANDO DISPUESTAS MUESCAS ADICIONALES (6) EN LA PARTE SUPERIOR DE, AL MENOS, CADA TERCERA PROTUBERANCIA (2). SE PUEDEN UNIR VARIOS SEGMENTOS (1) EN FILA HACIENDO QUE LAS PROTUSIONES (8) EN LA PARTE FRONTAL DE UNO DE LOS SEGMENTOS Y LOS ORIFICIOS CORRESPONDIENTES EN LA PARTE POSTERIOR DEL SIGUIENTE SEGMENTO (1) SE ENGANCHEN ENTRE SI. LA FILA, FORMADA DE LA MANERA DESCRITA, SE PUEDE UTILIZAR PARA EL TRATAMIENTO DE TODA LA COLUMNA VERTEBRAL SENCILLAMENTE PONIENDOLA CONTRA EL CUERPO PARA QUE LOS PARES DE PROTUSIONES DE CADA PROTUBERANCIA 2 SE APLIQUEN A LA COLUMNA VERTEBRAL A AMBOS LADOS DE LA MISMA. AL PONER LA FILA EN UNA BOLSA DE SUJECION CON SOPORTES ALREDEDOR DEL CUERPO, ES POSIBLE LLEVAR EL DISPOSITIVOEN LA POSICION ERGUIDA DEL CUERPO, POR EJEMPLO, DURANTE CUALQUIER ACTIVIDAD.
Patent ES-2093132-T3 (ES)
Inventor: AST HANS-PETER
IPC: G09F3/02
Filed: 1992-04-02
Granted: 1996-12-16
Abstract: The invention relates to a label, the underside of which is to be adhesively bonded, by means of an adhesive which is essentially completely soluble in a washing liquid, to an object, especially to an object made of plastic, and preferably to a bottle crate made of plastic, which label is characterised in that the adhesive is disposed on the underside of the label in the form of a pressure-sensitive layer essentially completely soluble in the washing liquid. <IMAGE>
Patent ES-2088049-T3 (ES)
Title: Dispositivo de extraccion de cartuchos.
Inventor: FOND OLIVIER
IPC: A47J31/34
Filed: 1992-06-25
Granted: 1996-08-01
Abstract: LA INVENCION SE REFIERE A UN DISPOSITIVO DE EXTRACCION DE CARTUCHOS QUE CONTIENEN UNA SUSTANCIA PARA LA PREPARACION DE UNA BEBIDA PREVISTO PARA SER MONTADO SOBRE UNA CABEZA DE EXTRACCION (1) QUE COMPRENDE UN SISTEMA DE INYECCION DE AGUA PRIMARIO (26, 7), UN ANILLO DE APRIETE PRIMARIO (2) CON RAMPAS DE APRIETE (3) COAXIALES CON EL SISTEMA DE INYECCION DE AGUA Y UNA JUNTA DE ESTANQUEIDAD (4). ESTE DISPOSITIVO COMPRENDE UN MEDIO DE FIJACION SECUNDARIO, UN PORTACARTUCHO (14) Y UN ORGANO DE AGUA SECUNDARIO (19, 18), COMPRENDIENDO DICHO MEDIO DE FIJACION SECUNDARIO EN EL EXTERIOR PATILLAS DE AJUSTE (10) PREVISTAS PARA INTRODUCIRSE SOBRE LAS RAMPAS DE APRIETE DEL ANILLO DE APRIETE PRIMARIO, EN EL INTERIOR UN ANILLO DE APRIETE SECUNDARIO (11) QUE PRESENTA RAMPAS DE APRIETE (12) SOBRE LAS QUE SE INTRODUCEN PATILLAS DE FIJACION DEL PORTACARTUCHO.
Patent ES-2202299-T3 (ES)
Title: Conjunto distribuidor de liquido.
Inventor: PETRICH TULLIO
IPC: B01D3/00
Filed: 1992-01-31
Granted: 2004-04-01
Abstract: UN CONJUNTO DISTRIBUIDOR QUE CONSTA DE UNA PLACA DISTRIBUIDORA ADAPTADA PARA POSICIONAMIENTO HORIZONTAL Y FIJACION A UN DISTRIBUIDOR DE LIQUIDO DE COLUMNA DE PROCESO PARA LA DESCARGA SIMETRICA DEL LIQUIDO DEL MISMO. LA PLACA DISTRIBUIDORA CONSTA DE UN MIEMBRO QUE TIENE PAREDES LATERALES FORMADAS ALREDEDOR DEL MISMO Y UNA MULTITUD DE ABERTURAS A PRESION DENTRO DEL MISMO. LA PLACA DISTRIBUIDORA ESTA CONSTRUIDA PARA RECOGER EL LIQUIDO DESCARGADO DEL DISTRIBUIDOR DE LIQUIDOS, EXTENDIENDO EL LIQUIDO A TRAVES DEL MISMO Y PERMITIENDO UNA DESCARGA IGUAL DE VELOCIDAD BAJA DEL LIQUIDO DEL MISMO EN UN COLCHON DE EMBALAJE DEBAJO DEL MISMO.
Patent ES-2117036-T3 (ES)
Inventor: CHEONG CATHERINE LOUISE
IPC: C08G101/00
Filed: 1992-11-06
Granted: 1998-08-01
Abstract: A polyurethane foam suitable for use as a wound-contact layer in a wound dressing is made by mixing 1 part by weight of an isocyanate-capped prepolymer having from 0.5 to 1.2 meq NCO groups/g with from 0.4 to 1.0 parts by weight of water in the presence of from 0.05 to 0.4 parts by weight of a C<5> to C<7> monohydric alcohol, and then drying the product. The monohydric alcohol is preferably methanol, and the isocyanate-capped prepolymer is preferably an isocyanate-capped ethyleneoxy/propyleneoxy copolymer.
Patent ES-2054601-T3 (ES)
Inventor: CAPUT DANIEL
IPC: C12N1/21
Filed: 1992-03-27
Granted: 1996-04-01
Abstract: The present invention relates to a protein possessing a cytokine type activity, or a precursor of this protein, which comprises the following amino acid sequence (a1): <IMAGE> in which Xaa represents Asp or Gly.o
Patent ES-2090574-T3 (ES)
Inventor: EHRET PHILIPPE
IPC: D06M101/18
Filed: 1992-09-30
Granted: 1996-10-16
Abstract: The storage system is made of a nonwoven made of filaments of thermoplastic polymers, shaped into a closed pouch containing a water-soluble active component. The pouch is intended to ensure a prolonged release, proceeding linearly, of the active component into an aqueous medium. For a given active component, the desired diffusion kinetics are obtained by adjusting the surface of the nonwoven and the degree of hydrophilicity of the latter, according to the availability of the active component. For this purpose, the nonwoven is impregnated either with a polysiloxane or a quaternary ammonium salt or with a perfluoro compound or a paraffin-acrylic resin.
Patent ES-2177526-T3 (ES)
Inventor: MCDONALD GEORGE WALLACE
IPC: B42D15/00
Filed: 1991-12-04
Granted: 2002-12-16
Abstract: PCT No. PCT/GB91/02154 Sec. 371 Date Sep. 22, 1992 Sec. 102(e) Date Sep. 22, 1992 PCT Filed Dec. 4, 1991 PCT Pub. No. WO92/10828 PCT Pub. Date Jun. 25, 1992.Sheet means (10) comprises a sheet of material (12) having mutually transverse sets of concertina folds (14, 16), sealing means (18, 20) to seal the same in a folded condition and defined opening means (18, 20), e.g. a marked and/or weakened break line (54) at which the sealing means can be opened, attachment means (36) for attaching the sheet means (10) to an article (28), diagonally opposite segments (22) of said sheet (12) being adapted one for attachment to the article and the other to be pulled free to open the sheet fully with a single movement once the sealing means have been opened. The penultimate section (80) and ultimate section (86) may project respectively beyond opposite sides (82, 88) of the underlying sections to allow adhesive strips (18, 20) to affix directly to the article (28) or only the ultimate thickness (segment) (26) may be extended (at 90) and so project. Sheet (12) may have a projecting tab (38 )with adhesive portions (40, 46) that folds over to cover the main part of the sheet and attach it to an article or may have a separate cover piece, e.g. in the form of a loop (58) surrounding the folded sheet.
Patent ES-2066602-T3 (ES)
Inventor: MABILE MICHEL
IPC: G01N33/542
Filed: 1992-01-27
Granted: 1995-03-01
Abstract: PCT No. PCT/FR92/00069 Sec. 371 Date Jul. 28, 1993 Sec. 102(e) Date Jul. 28, 1993 PCT Filed Jan. 27, 1992 PCT Pub. No. WO92/13264 PCT Pub. Date Aug. 6, 1992.The present invention relates to a method employing at least one luminescent tracer compound and a luminescent compound used as an internal reference, which, when exposed to the same excitation wavelength, are capable of emitting at difference wavelengths,  lambda 2 and  lambda 1 respectively, either by direct luminescence or by the induction of a luminescent emission, and correcting the measurement of the luminescence emitted by the tracer compound at wavelength  lambda 2 on the basis of the measurement of the luminescence emitted by the reference compound at wavelength  lambda 1.
Patent ES-2126594-T3 (ES)
Inventor: FLOM ATLE
IPC: B32B37/24
Filed: 1992-07-23
Granted: 1999-04-01
Abstract: A laminating method comprises:   (a) applying a moisture barrier layer (8) to the outside of a relatively stiff substrate (1) to form a preliminary laminate (1,8), (b) extrusion laminating the preliminary laminate (1,8), a thermoplastics layer (2) and a film (3,3') comprised of a barrier polymer layer (4), by applying the thermoplastics layer (2) in a molten state to between the inside of the preliminary laminate (1,8) and the film (3,3'), and (c) applying a second moisture barrier layer (7) to the inside of the film (3,3').   <IMAGE>
Patent ES-2095500-T3 (ES)
Inventor: SEDUN FREDERICK S
IPC: A01N37/06
Filed: 1992-12-08
Granted: 1997-02-16
Abstract: An environmentally compatible, non-phytotoxic anti-fungal composition is provided having an active ingredient which comprises a fatty acid metal salt having from 4 to 18 carbon atoms. The metal salt may be formed from metals including calcium, copper, magnesium, and zinc. Additional formulation enhancing agents, such as dispersants, wetting agents and gums, are typically included within the composition. The composition is advantageous in that it exhibits a residual fungicidal effect lasting up to 2 months.
Patent ES-2099313-T3 (ES)
Inventor: GABATHULER WALTER
IPC: B61D1/06
Filed: 1993-05-12
Granted: 1997-05-16
Abstract: Modular concept for the body of a doubledeck railway carriage body which is assembled from a number of modules which are conceived differently with respect to the purpose of use and design, the different modules being capable of being combined differently within an assigned range. A panorama module (1), a first class module (2) and a second class module (3) are present as upper deck modules. The three upper deck modules (1-3), which are provided with an integrated hollow chamber base plate, form, in terms of rigidity, the load-bearing part of the body of the carriage. Below the upper deck modules (1-3), the lower-deck passenger modules (5,7,8,9), the staircase modules (10,13), the entry modules (6), a technical module (4) and, at the ends, the intercommunicating modules (11,12) are added. A driver's stand module (14) completes the double-deck carriage body to form a control carriage body. The modules (1-14) are connected to one another with releasable connections in a positively and frictionally engaging and sealing fashion. <IMAGE>
Patent ES-2099336-T3 (ES)
Inventor: WEBER MANFRED
IPC: D06M101/16
Filed: 1993-09-20
Granted: 1997-05-16
Abstract: Described is a flame-retardant (low-flammability) carpet (floor covering) consisting of a backing material (1), a tied-in pile yarn (2) and a back finish (3), wherein the pile yarn consists of low flammability synthetic fibres, the backing material consists of normal or low flammability synthetic fibres and the back finish consists of a polyurethane composed of the radicals of the formulae I to VII: <IMAGE>  where   A1 is an aliphatic radical having from 2 to 12, preferably 4-10, in particular 4-8, carbon atoms,   A2 is a phenyl radical, preferably an o-, m- or p-phenyl radical, A3 is an aliphatic radical having 2-10, preferably 4-8, carbon atoms, with n and m each being 1 or 2 and n+m being 3 or 4, preferably 3, and each of the n oxygen atoms being attached to A3, B1 is an aliphatic or cycloaliphatic radical having 2-10, preferably 4-8, carbon atoms, B2 is an aliphatic or cycloaliphatic radical having 3-6 carbon atoms, preferably an aliphatic radical having 3 or 4 carbon atoms with p being 1 or 2 and each of the p oxygen atoms being attached to B2, C1 is an aliphatic or mono- or bicyclic cycloaliphatic radical having from 2 to 12 carbon atoms, preferably 5-12 carbon atoms, and D1 is an aliphatic or mono- or bicyclic cycloaliphatic radical having from 5 to 36 carbon atoms, preferably 6-20, in particular 10-16, carbon atoms, the proportions of the radicals I to III, based on their total amount, are within the following limits:     I: 40 to 80 mol%,   II: 10 to 40 mol%,   III: 0 to 25 mol%, the proportions of the radicals IV, V and VI, based on their total amount, are within the following limits:     IV: 65 to 95 mol%,   V: 0 to 19 mol%,   VI: 3 to 16 mol%, the radicals of the formulae I, II and IV form polyester blocks having an average molecular weight from 400 to 6000, and the proportions of the radicals of the formula VII, based on the total amount of all the components of the polyurethane resin, are from 5 to 35 mol%, preferably from 10 to 25 mol%, and a process for producing the flame-retardant carpet. There is further described an aqueous preparation containing this polyurethane resin and its use for textile finishing. <IMAGE>
Patent ES-2210233-T3 (ES)
Inventor: BOOP GREGORY W
IPC: H04J3/12
Filed: 1993-09-21
Granted: 2004-07-01
Abstract: A serial rate conversion circuit converts the serial rate of a stream of signals, for example, from a SONET overhead data link (ODL) rate of 6.48 Mb/s to and from a data communications channel (DCC) rate of 4.096 Mb/s. The circuit includes a low data flow memory and address select circuit for communicating the stream of serial formatted signals at a low data flowrate and a high data flow memory and address select circuit for communicating the stream of serial formatted signals at a high data flowrate. Clock rate conversion circuitry associates between the low data flow memory and address circuit and the high data flow memory and address select circuit to convert the high data flow serial formatted signals back and forth between the low data flowrate and the high data flowrate while maintaining said stream in a serial format. To provide jitter tolerance during the serial rate conversion process, the high data flowrate frame associates with the low data flowrate frame so that the low data flowrate frame elements are cushioned or buffered by leading and following high data flowrate frame elements. <IMAGE>   <IMAGE>
Patent ES-2081176-T3 (ES)
Inventor: MINTZ MARCUS
IPC: A22C13/00
Filed: 1993-02-17
Granted: 1996-02-16
Abstract: A stockinette member (3) is formed of closely knit or woven threads. A netting arrangement is integrally formed with the stockinette member. The netting arrangement may either be knit in with the stockinette member or the strands (5,7) of the netting arrangement may be laid in. <IMAGE>
Patent ES-2196007-T3 (ES)
Inventor: WARREN KENNETH G
IPC: C07K14/47
Filed: 1992-10-15
Granted: 2003-12-16
Abstract: Human basic myelin protein (h-MBP) has a molecular weight of 18.5 KD and contains 170 amino acid residues. Synthetic peptides ranging in length from 8 to 25 residues and covering the entire length of the protein have been produced. Antibodies to h-MBP (anti-MBP) were found to be neutralized by the synthetic peptides, which span the h-MBP from about amino acid residue (61) to about amino acid residue (106). The synthetic peptides, which cover both the amino (about residues 1 to 63) and carboxy (about residues 117 to 162) terminals of h-MBP did not neutralize purified anti-MBP. Accordingly, intrathecal administration of selected synthetic MBP peptides may be used as a treatment for Multiple Sclerosis by neutralizing anti-MBP.
Patent ES-2098766-T3 (ES)
Inventor: BENCSITS FRANZ
IPC: A01N37/02
Filed: 1993-07-27
Granted: 1997-05-01
Abstract: The present invention relates to the use of natural or synthetic first runnings coconut fatty acid as an insect-repellent agent which is applied to human or animal skin or to clothing.
Patent ES-2118260-T3 (ES)
Inventor: KUDELSKI ANDRE
IPC: H04N7/16
Filed: 1993-10-08
Granted: 1998-09-16
Abstract: PCT No. PCT/EP93/02773 Sec. 371 Date Jun. 9, 1994 Sec. 102(e) Date Jun. 9, 1994 PCT Filed Oct. 8, 1993 PCT Pub. No. WO94/09453 PCT Pub. Date Apr. 28, 1994.A data processing system comprises a set of memory cards (10) and at least one central administration and processing unit (22). According to the invention, the memory cards and the processing unit together form a relational database. Each memory card contains a memory (28) for storing a set of instructions (A1, A2, . . . , An), each instruction containing a logical link with at least one other instruction. The system is applicable notably to pay-TV and other restricted access systems, for example in banking.
Patent ES-2127870-T3 (ES)
Title: Aparato acondicionador de aire utilizable con un amplio margen de tension de alimentacion.
Inventor: KIKUIRI YOSHIO
IPC: H02M5/458
Filed: 1994-10-26
Granted: 1999-05-01
Abstract: UN ACONDICIONADOR DE AIRE QUE TIENE UN COMPRESOR DE POTENCIA VARIABLE, UN INVERSOR PARA VARIAR LA FRECUENCIA DE MANDO DEL COMPRESOR A TRAVES DE UN CONTROL V/F, UN CONTROLADOR PARA SUMINISTRAR UNA INSTRUCCION DE CONTROL DE FRECUENCIA VARIABLE DE ACUERDO CON LA CARGA DE AIRE ACONDICIONADO AL INVERSOR, Y UN DETECTOR DE VOLTAJE DE ENTRADA PARA DETECTAR UNA ENTRADA DE VOLTAJE GENERADOR AL INVERSOR, EL CONTROLADOR INCLUYE UNOS ELEMENTOS DE REFERENCIA PARA ALMACENAR PREVIAMENTE LOS DATOS DE VALORES V/F CORRESPONDIENTES A VARIAS SECCIONES DE VOLTAJE HACIA LAS CUALES SE DIVIDE UNA GAMA PREDETERMINADA DEL VOLTAJE DE ENTRADA AL INVERSOR EN UN INTERVALO DE VOLTAJE PREDETERMINADO, Y SELECCIONA DATOS QUE REPRESENTAN LA PROPORCION (V/F) DEL VOLTAJE DE SALIDA (V) CORRESPONDIENTE AL VOLTAJE DE ENTRADA DETECTADO, Y LA FRECUENCIA DE MANDO (F) A PARTIR DE LOS ELEMENTOS DE REFERENCIA PARA EXTRAER LA INSTRUCCION DE CONTROL DE FRECUENCIA VARIABLE DEL INVERSOR DE FORMA QUE SE LLEVE A CABO LA OPERACION DE ACONDICIONAMIENTO DE AIRE DE ACUERDO CON LA CARGA DE AIRE ACONDICIONADO.
Patent ES-2107804-T3 (ES)
Inventor: GOBBO STEVEN ALPHONSE
IPC: A23F3/16
Filed: 1993-12-16
Granted: 1997-12-01
Abstract: Tea products as well as a process for their preparation are described. They are prepared by adding high methoxy pectin to an acidified tea extract obtained from low temperature extraction.
Patent ES-2104351-T3 (ES)
Inventor: KIENOW EKKEHARD
IPC: B01J20/20
Filed: 1994-02-04
Granted: 1997-10-01
Abstract: A powdered medium for the cleaning of exhaust gases, e,g. smoke and gases from industrial chimneys, employing the principle of dry adsorption, which includes a mixture of activated cokes with inert materials which have no dust explosiveness To prepare a mixture containing powdered activated cokes, in which mixture the concentration of carbon is up to 30% by weight and which when used in the airstream process under essentially all operating conditions, is not subject to virtually any fluctuations in concentration such that with a concentration of oxygen up to 21% by volume, no dust-explosive fractions can form, at least one inert material component in the mixture is matched in terms of its grain size distribution to the grain size distribution of the activated coke component, so that in a gas medium at rest, the speed of vertical descent of the coarse grain of the inert material components is substantially equal to or greater than the speed of vertical descent of the coarse grain of the activated coke components. The powdered medium can be used in essentially all exhaust gas cleaning systems, in separately operated or upstream or downstream adsorption stages employing the airstream principle.
Patent ES-2138658-T3 (ES)
Title: Sistema de estanqueidad.
Inventor: MOHN FRANK
IPC: F16J15/40
Filed: 1994-04-13
Granted: 2000-01-16
Abstract: UN PISTON QUE SUFRE UN MOVIMIENTO DE VAIVEN DENTRO DE UN CILINDRO SE SELLA CON RESPECTO A LA PARED DEL CILINDRO MEDIANTE UN FLUIDO A UNA PRESION MAYOR QUE LA DE LOS FLUIDOS SOBRE LOS LADOS OPUESTOS DEL PISTON SUMINISTRADO AL ESPACIO (18) ENTRE LOS DOS SELLAMIENTOS (19, 20) QUE FUNCIONAN ENTRE EL PISTON Y LA PARED DEL CILINDRO, SE SUMINISTRA UN ACUMULADOR O UNA CAMARA INTENSIFICADORA AUXILIAR (67) A PARTIR DE LA CUAL EL FLUIDO A PRESION ES SUMINISTRADO AL ESPACIO ENTRE LOS DOS SELLAMIENTOS PARA REGULAR LA PRESION ENTRE ELLOS. LOS DOS SELLAMIENTOS ENTRE EL PISTON Y LA PARED DEL CILINDRO PUEDEN ESTAR CONSTITUIDOS RESPECTIVAMENTE MEDIANTE UN PRIMER (19A-19C) Y UN SEGUNDO (20A20C) GRUPO O PLURALIDAD DE SEGMENTOS DE SELLAMIENTO SEPARADOS SELECCIONADOS TENIENDO EN CUENTA EL MATERIAL Y LAS DIMENSIONES DE MANERA QUE REALICEN FUNCIONES ESPECIFICAS. TAMBIEN, UN SISTEMA DE SELLAMIENTO ENTRE UN PISTON Y UN CILINDRO DENTRO DE CUAL EL PISTON SE MUEVE CON UN MOVIMIENTO DE VAIVEN PUEDE COMPRENDER UN SELLAMIENTO DELANTERO (19, 20), QUE TIENE CONVENIENTEMENTE DOS SELLAMIENTOS O GRUPOS DE SEGMENTOS DE SELLAMIENTO SEGUN SE DESCRIBE, SEPARANDO UN FLUIDO DE PROCESAMIENTO O DE TRABAJO (4) QUE ES MOVIDO POR EL PISTON DE UN SEGUNDO FLUIDO (7) EN EL ESPACIO ALREDEDOR DEL PISTON, Y UN SELLAMIENTO DE BARRERA SEPARADO HACIA ATRAS (21A-21C) QUE SEPARA EL SEGUNDO FLUIDO DE UN TERCER FLUIDO QUE LLENA UN ALOJAMIENTO (6) QUE CONTIENE UN MOTOR MEDIANTE EL CUAL ES IMPULSADO EL PISTON.
Patent ES-2196028-T3 (ES)
Inventor: BAILEY AUSTIN
IPC: A61K9/127
Filed: 1994-04-12
Granted: 2003-12-16
Abstract: A liposome composition is provided which contains a liposome having: (i) an outermost lipid bilayer containing, in addition to a neutral, bilayer-preferring lipid, a fusion-promoting effective amount of an ionizable lipid having a protonatable, cationic headgroup and an unsaturated acyl chain; and (ii) a compartment adjacent to the outermost lipid bilayer which contains an aqueous solution having a first pH. External to the liposome in the composition is an aqueous solution having a second pH. The first pH is less than the pKa of the ionizable lipid in the outermost lipid bilayer and the second pH is greater than the pKa of the ionizable lipid in the outermost lipid bilayer, such that there is a pH gradient across the outermost lipid bilayer and the ionizable lipid is accumulated in the inner monolayer of the outermost lipid bilayer in response to the gradient. The liposome can be fused in a controlled manner to another lipid bilayer, for example, the plasma membrane of a mammalian cell, by degrading the pH gradient when fusion is to occur, such that the ionizable lipid is neutral, evenly distributed in the outermost lipid bilayer and, fusogenic. Controlled fusion can be used to control the delivery of a biologically active agent entrapped in the liposome into a cell.
Patent ES-2129654-T3 (ES)
Inventor: PURDIE NEIL
IPC: G01N21/64
Filed: 1994-07-13
Granted: 1999-06-16
Abstract: The present invention relates to the direct quantitative determination of cholesterol and involves the formation of a spectrophotometrically active product of cholesterol obtained by contacting cholesterol with an acyl compound and a perchlorate effective to form the spectrophotometrically active product.
Patent ES-2096482-T3 (ES)
Title: Procedimiento de mejora del molido de materias crudas.
Inventor: GUICQUERO JEAN-PIERRE
IPC: B02C23/06
Filed: 1994-08-04
Granted: 1997-03-01
Abstract: LA INVENCION SE REFIERE A UN PROCESO DE MEJORA DE LA TRITURACION DE MATERIALES CRUDOS CARACTERIZADO EN QUE SE REALIZA LA TRITURACION DE LOS MATERIALES CRUDOS EN PRESENCIA DE UN AGENTE DE TRITURACION QUE COMPRENDE AL MENOS UN ACIDO MONOCARBOXILICO DE CADENA CORTA QUE COMPRENDE AL MENOS OCHO ATOMOS DE CARBONO, ESTANDO LA CANDIDAD DE ESTE AGENTE DE TRITURACION COMPRENDIDA ENTRE 0,01% Y 0,1% EN PESO RESPECTO DE LOS MATERIALES CRUDOS, O BIEN ENTRE 100 Y 1000PPM O GRAMOS/TONELADA.