baber/WOPTO huggingface dataset:
Patent CA-2598271-A1 (CA)
Title: Pharmacokinetically improved compounds
Inventor: SWEETNAM PAUL
IPC: A61K31/53
Filed: 2006-02-21
Abstract: A compound of formula A having improved non-specific binding characteristics and pharmacokinetic properties is provided: or pharmaceutically acceptable salt, stereoisomer, or hydrate thereof, wherein R1 is lower alkyl, R2 and R3 are independently selected from lower alkyl, and lower alkenyl and lower alkynyl, wherein the lower alkyl, lower alkenyl, and lower alkynyl may be optionally substituted with one or more halogen, lower alkoxy, hydroxy, CN, NO2, amino, acylamino, amido, carbonyl, and alkylthio, A is N or C-H, B is N, C-H, C-(SO2-R4), or C-CO-R4, D is N, C-H, C-(SO2-R4) or C-CO-R4, E is N or C-H, wherein only one of A, B or E may be N, and one of B or D is C-(SO2-R4) or C-CO-R4, R4 is a group having the formula: in which each R , R , R and R are independently selected from H and lower alkyl, wherein the lower alkyl may be optionally substituted with one or more halogen, lower alkoxy, hydroxy, CN, NO2, amino, acylamino, amido, carbonyl, and alkylthio; and additionally or alternatively R6 and R5 together form a 5- or 6-membered ring, or R6 and R7 together form a 3 to 6 membered ring; R9 is independently selected from H and lower alkyl, wherein the lower alkyl may be optionally substituted with one or more halogen, lower alkoxy, hydroxy, CN, NO2, amino, acylamino, amido, carbonyl, and alkylthio; alternatively R and R together with the nitrogen to which they are attached form a 5- or 6-membered ring; n is 1 to 4; and m is 1 to 6.
Patent CA-2601997-A1 (CA)
Title: Control device
Inventor: NILSAGARD JONAS
IPC: G06F3/033
Filed: 2006-03-17
Abstract: A control device (1 ) for providing four position parameters of an object (7) attached to a displacement device (6) using a rotatabie structure (2) with three determinable position parameters: x and y tilt and rotational angle around a z axis; the forth parameter being position in the z direction of the displacement device (6).
Patent CA-2603121-A1 (CA)
Inventor: LENTI KIM M
IPC: C22B15/00
Filed: 2006-03-31
Abstract: A method of operating a channel induction furnace so as to receive electric arc furnace (EAF) dust, basic oxygen furnace (BOF) sludge/dust and/or other iron and volatile metals containing materials as a feed stream on a batch, continuous or semi-continuous basis together with a iron-containing material feed, and therefrom produce an iron-containing hot metal or pig iron product while recovering iron value from the feed materials and recovering volatile metal components contained in the feed materials.
Patent CA-2609578-A1 (CA)
Title: Ethernet voltage source apparatus and method
Inventor: O'CONNOR MICHAEL JERRY
IPC: H04L12/10
Filed: 2007-11-05
Abstract: An Ethernet voltage source apparatus and method. The apparatus includes an electrical connector, a receiving circuit electrically connected to the Ethernet cable connector, a voltage regulator/power conditioning circuit electrically connected to the receiving circuit, and a first interface output connector electrically connected to the voltage regulator/power conditioning circuit. The receiving circuit receives a first voltage signal and an Ethernet data signal from the Ethernet cable. The receiving circuit separates the first voltage signal from the Ethernet data signal. The voltage regulator/power conditioning circuit generates a second voltage signal from the first voltage signal. The second voltage signal is configured as a first power source for an industrial/commercial device. The first interface output connector is configured to electrically connect the second voltage signal to the industrial/commercial device.
Patent CA-2609626-A1 (CA)
Title: Composition comprising l-arginine, crataegus, artichoke flavonoids and citruilline for improving blood flow in working muscles
Inventor: MOLINO MICHELE
IPC: A61K31/352
Filed: 2007-11-27
Abstract: A nutritional composition and method is provided for increasing blood flow to skeletal muscle in an individual by supporting the biological activity of nitric oxide comprising therapeutically effective amounts of L-arginine, Crataegus extract and Artichoke flavonoids.
Patent CA-2610886-A1 (CA)
Inventor: SONGWE NEVILLE JR
IPC: B62D3/00
Filed: 2006-06-06
Abstract: An instrument panel, for use with a vehicle including a body, wheels, a driver seat, and an engine, is configured to be disposed at least partially in front of the seat and includes a steering wheel disposed in front of the seat, a display configured to provide information to a person seated in the seat, and a modular housing configured to hold the display and the steering wheel, the steering wheel being rotatably connected to the housing, the display connected to the housing, the housing extending substantially an entire width of a passenger area of the vehicle, the modular housing including independent sections that can be removed and replaced independently of any other section of the housing.
Patent CA-2613184-A1 (CA)
Title: Fine-particled polymer dispersions containing starch
Inventor: ETTL ROLAND
IPC: D21H17/37
Filed: 2006-06-23
Abstract: The invention relates to fine-particled polymer dispersions which contain starch and which are obtained by emulsion copolymerisation with redox initiators of ethylenically unsaturated monomers from the group containing (a) 45 - 55 wt. % of at least one, optionally substituted, styrene, methacrylic acid methylester, acrylonitrile and/or methacrylonitrile, (b) 15 - 29 wt.- %  of at least one acrylic acid-C1-C12-alkyl ester and/or a methacrylic acid-C2-C12-alkyl ester and, (c) 0 - 10 wt.- % of at least one other ethylenically unsaturated copolymerisable monomer, in an aqueous medium in the presence of (d) 15 - 35 wt. % of a degraded cationised starch, which has a molar mass Mw of between 1000 - 65 000. The total (a) + (b) + (c) + (d) = 100 % and refers to the total content of solid material. The invention also relates to a method for producing said type of polymer dispersions by means of emulsion polymerisation of the monomers (a), (b) and (c) in an aqueous medium with redox initiators in the presence of (d) cationic starch and to the use of polymer dispersions containing starch as resizing agents for paper, pulp and cardboard.
Patent CA-2617660-A1 (CA)
Title: Multi-drug ligand conjugates
Inventor: VLAHOV IONTCHO RADOSLAVOV
IPC: A61K47/48
Filed: 2006-08-18
Abstract: Described herein are compounds, pharmaceutical compositions and methods for treating pathogenic cell populations in a patient. The compounds described herein include conjugates of a plurality of cytotoxic drugs and vitamin receptor binding ligands. The plurality of drugs may be the same or different.  Similarly, the vitamin receptor binding ligands may be the same or different.  The conjugates also include a linker that is formed from one or more spacer linkers, heteroatom linkers, and releasable linkers.
Patent CA-2618105-A1 (CA)
Inventor: CRENSHAW HUGH C
IPC: B01D11/00
Filed: 2006-08-10
Abstract: Micro fluidic Systems, Devices and Methods for Reducing Diffusion and Compliance Effects at a Fluid Mixing Region (110). According to one embodiment, a micro fluidic device is provided for combining fluids in a mixing region. The micro fluidic device can include a fluid-mixing region connected to a first and second micro scale channel. The micro scale channels can advance fluids to the fluid-mixing region. The micro scale channels can include constricted flow portions. According to another embodiment, the micro scale channels can be connected to waste channels for removing fluid diffused into one of the channels from the other channel. According to yet another embodiment, a micro fluidic system is provided for controlling the flow of fluids through the micro scale channels for reducing or eliminating diffusion between the channels (108).
Patent CA-2620577-A1 (CA)
Title: Mimetiques peptidiques de l'hormone de stimulation des melanocytes
Inventor: ROTH JESSE
IPC: A61K38/16
Filed: 2006-09-01
Abstract: L'invention concerne des peptides présentant une activité d'hormone de stimulation des mélanocytes. L'invention concerne également des vecteurs codant pour ces peptides et des cellules transgéniques comprenant ces vecteurs. L'invention se rapporte en outre à des méthodes destinées à réduire ou prévenir la libération d'une cytokine inflammatoire à partir de cellules de mammifères, ainsi qu'à des méthodes destinées à traiter un mammifère souffrant ou risquant de souffrir d'une affection médiée par une cascade de cytokines inflammatoires. Par ailleurs, l'invention concerne des méthodes destinées à réduire les taux d'une cytokine inflammatoire chez un mammifère, des méthodes destinées à traiter un mammifère présentant un surpoids, des méthodes destinées à réduire les ingesta chez un mammifère et des méthodes destinées à inhiber l'immunité innée dans le système digestif d'un mammifère.
Patent CA-2622208-A1 (CA)
Inventor: ABRAHAM MARK A
IPC: F01N3/023
Filed: 2008-02-26
Abstract: A motor vehicle operator interface and control algorithm convey diesel particulate filter regeneration status to the operator. The algorithm also allows new control over heretofore automatic regeneration, through limiting the inhibit function.  The DPF after-treatment operator interface provides multiple status indications to the operator. In a preferred embodiment this is effected using a switched indicator lamp.
Patent CA-2622664-A1 (CA)
Title: Heating assembly
Inventor: KING RAY
IPC: F24H9/20
Filed: 2008-02-28
Abstract: A heating assembly comprising a housing having an air passageway extending therethrough for passage and flow of air through the housing, and at least one heating element is removably mounted to an interior surface of the housing, projecting into the housing, so as to be in direct contact with the air therein. The heating element is supplied with electrical power from a power source for enabling the heating element to heat the air. A thermostatic safety control is provided in association with the heating element, which is adapted to turn the heating element off when a temperature of the air exceeds a pre-determined level. An air blower is also provided for directing heated air within the housing to an area external to the heating assembly. In another embodiment, a remote device can be used to selectively activate, or deactivate, the heating element. The heating assembly can be interconnected to existing air duct work in a home, wherein the heating assembly can work in the home independently of, and without interfering with, an installed furnace.
Patent CA-2622667-A1 (CA)
Title: Device, system, and method of discriminately handling a wideband transmission in a communication network
Inventor: STRULL YESHAYAHU
IPC: H04N7/173
Filed: 2006-09-11
Abstract: Embodiments of the invention provide a method, device and system of discriminately handling a wideband transmission including a legacy frequency signal of a legacy frequency band and an extended frequency signal of an extended 5 frequency band. In some demonstrative embodiments a signal discrimination device includes a signal adjustment module to generate an adjusted signal corresponding to the legacy frequency signal; a first multiplexer to selectively route the legacy frequency signal from a first terminal of the signal discrimination device to the signal adjustment module;  and a second multiplexer to selectively route the adjusted signal 0 to a second terminal of the signal discrimination device, wherein the first multiplexer is able to selectively route an extended frequency signal of the extended frequency band from the first terminal to the second multiplexer, and wherein the second multiplexer is able to selectively route the extended signal to the second terminal. Other embodiments are described and claimed.
Patent CA-2627840-A1 (CA)
Inventor: BLACKMORE ANDREW
IPC: H01B5/08
Filed: 2008-03-31
Abstract: A four layer multi-strand unilay cable of nominally 61 strands is formed without the aid of roll forming drives but rather by reliance on the tension in the strands provided by a pair of drive capstans carried in a single twist cage. The area reduction of the cable in the various roll forming stages is less than about 15 or 16 %, and may be in the range of about 12 - 14 %. The area reduction is greater than 10 %. The process is fed by stationary reels, and the feedstock may be replenished by splicing subsequent stock into the tail end of the stock of the preceding reel without having to cease production. The output reel may be greater than 76 inches in diameter, and may be 84 or 96 inches in some cases.  The line does not employ the large number of roll forming drives and drive metering devices that would be used if all stations were actively driven. The cables so produced are twisted together under tension, and the elements of those cables may tend to bind against each other when formed and twisted. The copper or aluminum cables so formed may then be coated in a plastic dielectric coating.
Patent CA-2634479-A1 (CA)
Title: Thermosetting neutralized chitosan composition forming a hydrogel, lyophilizate, and processes for producing the same
Inventor: SCHUETZ YANNIC
IPC: C08B37/00
Filed: 2005-12-23
Abstract: The aqueous thermosetting neutralized chitosan composition, forming a phosphate-free transparent hydrogel at a temperature higher than 5° C., comprises 0.1 to 5.0 w/w %, based on the total composition, of a reacetylated chitosan having a molecular weight of not smaller than 100 kDa and a deacetylation degree of 40 to 70%, neutralized with an hydroxylated base, and 1 to 30 w/w %, based on the total composition, of a complexing agent selected from polyoses and polyols derived from polyoses. Said composition is useful for the preparation of an injectable formulation.
Patent CA-2634888-A1 (CA)
Inventor: DOMINOWSKI PAUL JOSEPH
IPC: C07H13/12
Filed: 2007-01-15
Abstract: This invention relates to compositions and methods of preparing stable adjuvant diluent stock solutions and final adjuvant solutions comprising glycolipids, weak acids, alcohols, nonionic surfactants and buffers.
Patent CA-2639461-A1 (CA)
Inventor: SHARMA DEEPAK KUMAR
IPC: G01N15/00
Filed: 2008-09-11
Abstract: The present invention provides a plurality of samples, each of which includes particles of a predetermined particle dimension, within narrow predetermined limits, dispersed in a carrier at a predetermined particle concentration. The predetermined particle dimension and the predetermined particle concentration are the same for each sample. However, advantageously, each sample has a different predetermined ratio of a value of an optical property of the particles to a value of the same optical property of the carrier. The present invention also provides a method for selecting a target sample from the plurality of samples to assess the measurement accuracy or the detection sensitivity of an optical particle analyzer as the predetermined ratio approaches 1.
Patent CA-2641841-A1 (CA)
Title: Method and apparatus for integrated entity and integrated operations of personalized data resource across the world wide web for online and offline interactions
Inventor: NG JOANNA W
IPC: G06Q30/00
Filed: 2008-10-24
Abstract: Embodiments of the invention provide a method and apparatus for integrated entity of personalized data resource across the WWW with integrated operations. Such embodiments can reside on premises (or service side) as an integrated personalized data resource which is constructed from each of a number of web applications over the Internet that fetch and provide a piece of user information. One embodiment of the invention is directed to a computer that has the method and apparatus associated with the designated user. It is operable to receive informational data from multiple information sources, wherein the data received from each source has a user or web application defined association with a plurality of semantic categories via tagging, and the data received from at least two different sources pertains to the same category (or tag).
Patent CA-2642534-A1 (CA)
Inventor: ROETKER JOHN J
IPC: F25D23/12
Filed: 2008-10-31
Abstract: A refrigerator includes a main body defining a storage space therein and a door for opening and closing the storage space. The refrigerator comprises a water conduit for directing water supplied from an external water source to the main body of the refrigerator. An inlet valve distributes the water supplied from the water conduit into a hot water conduit and a separate cold water conduit. A cold water tank is mounted to one of the main body and the door for cooling the water supplied through the cold water conduit and then storing the cooled water therein. A hot water tube is mounted to one of the main body and the door for receiving the water supplied through the hot water conduit. The hot water tube includes a heater operably installed within the hot water tube and in direct contact with the water therein. The heater generates heat through the application of electric power thereto to heat the water within the hot water tube to a predetermined temperature. The hot water tube heats water on demand so that no separate hot water tank for storing hot water therein is required. A dispenser is installed on the door for dispensing the hot and cold water supplied from the hot water tube and cold water tank to the outside of the refrigerator.
Patent CA-2643200-A1 (CA)
Title: Production of biologically active proteins
Inventor: LUDEVID MUGICA MARIA DOLORES
IPC: C12N5/10
Filed: 2007-02-23
Abstract: A fusion protein that is expressed in a recombinant protein body-like assembly (RPBLA) in host eukaryotic cells and organisms is disclosed. More particularly, a biologically active polypeptide fused to a protein sequence that mediates the induction of RPBLA formation is expressed and accumulated in host cells after transformation with an appropriate vector. The eukaryotic host cell does not produce protein bodies in the absence of the fusion protein. Methods for preparing and using the RPBLAs and the fusion protein are also disclosed, as are nucleic acid molecules that encode the fusion proteins.
Patent CA-2644274-A1 (CA)
Title: Multi-zone gas fireplace system and method for control
Inventor: HILLS DOUGLAS
IPC: F24C3/00
Filed: 2007-03-07
Abstract: A multi-zone gas fireplace system and method for control are provided. An exemplary embodiment of the multi-zone gas fireplace system comprises a firebox, a multi-zone burner system, and a control system. The multi-zone burner system comprises a plurality of burners located in a plurality of zones, a plurality of control valves coupled to the plurality of burners, a gas supply which supplies a gas to the burners, and an ignition source configured to ignite the gas. The control system comprises an input element responsive to a user input, a processor in communication with the input element, and an output element in communication with the processor, such that the control system is operative to automatically provide a variable flame display in conjunction with the multi-zone burner system.
Patent CA-2645234-A1 (CA)
Inventor: MURPHY BRYAN PATRICK
IPC: A61K8/49
Filed: 2007-03-06
Abstract: Compositions for dyeing keratin fibers comprise (a) at least one keratin dyeing compound selected from aromatic systems which comprise at least one boronic acid or boronic ester moiety and which are capable of forming upon oxidation a nucleophile or an electrophile, (b) at least one additional keratin dyeing compound selected from the group consisting of auxiliary developers and auxiliary couplers, and (c) a cosmetically suitable medium. Methods for oxidatively dyeing keratin fibers comprise the steps of applying such compositions in the presence of an oxidizing agent and rinsing the hair. A hair coloring product in kit form comprises a first separately packaged container comprising a composition as described above and a second separately packaged container comprising an oxidizing agent.
Patent CA-2646208-A1 (CA)
Inventor: FREEMAN THOMAS
IPC: A61K35/12
Filed: 2008-12-11
Abstract: Bone marrow stromal cells (BMSC) differentiate into neuron-like phenotypes in vitro and in vivo, engrafted into normal or denervated rat striatum. The BMSC administered into the ventricle did not remain localized to the site of the graft, but migrated throughout the brain and integrated into specific brain regions in various architectonic patterns. The most orderly integration of BMSC was in the laminar distribution of cerebellar Purkinje cells, where the BMSC-derived cells took on the Purkinje phenotype. The BMSC exhibited site-dependent differentiation and expressed several neuronal markers including neuron-specific nuclear protein, tyrosine hydroxylase and calbindin. Treated BMSC implanted intrastriatally stayed in the cortex and the striatum, produced tyrosine hydroxylase which produces the dopamine needed in Parkinson's disease.
Patent CA-2648041-A1 (CA)
Title: Method and apparatus for leak testing
Inventor: LEHMANN MARTIN
IPC: G01L21/12
Filed: 1998-03-10
Abstract: The invention relates to a technique for leak testing closed and filled containers, a method for producing closed and filled containers, and a leak testing apparatus. One aspect of the invention provides a method for leak testing at least one closed container, comprising applying a pressure difference across at least a part of the wall of the container, which part is to be leak tested, and monitoring the pressure on one side of the wall over a test time period as a leak indicative signal, and the method including:  establishing a pressure reference signal; generating a dynamic signal range that represent an acceptable change across the part during the test period with respect to the pressure reference signal; monitoring whether a signal derived from the pressure monitored is, or is not, within the dynamic signal range; and enabling the signal derived from the pressure monitored to update the dynamic signal range, if the signal derived from the pressure monitored is within the dynamic signal range, thereby indicating the container to fulfill a predetermined condition of acceptable pressure change with respect to leakiness.
Patent CA-2648784-A1 (CA)
Title: Distribution de contenu multimedia interactif a l'aide d'un reseau de communications a canal de retour
Inventor: BOVENSCHULTE DAVID
IPC: H04N7/173
Filed: 2007-04-11
Abstract: L'invention concerne des systèmes, des dispositifs et des procédés de guidage multimédia interactifs qui permettent la distribution de contenu multimédia et/ou le contrôle par un utilisateur de contenu multimédia par l'intermédiaire d'un dispositif d'équipement utilisateur capable de s'interfacer avec une source de contenu multimédia à l'aide d'un réseau à canal de retour.
Patent CA-2649208-A1 (CA)
Title: Method for repairing a damaged outer skin region on an aircraft
Inventor: ERDMANN WOLFGANG
IPC: C23C24/04
Filed: 2006-05-26
Abstract: The invention relates to a method for repairing a damaged outer skin region on an aircraft, in which the possibility exists for repairing possible damage to a plated layer, which is adhered to the outer skin of a passenger aircraft and protects the latter in the undamaged state from corrosion. With it, the plated layer can be repeated in the area of existing damage without incidental reworking.
Patent CA-2649757-A1 (CA)
Title: Cushioning member
Inventor: SNOW REBECCA E
IPC: A43B13/20
Filed: 2007-04-26
Abstract: A cushioning member for an article of footwear is disclosed. The article of footwear comprises a sole; and a cushioning member disposed in the sole, the cushioning member comprising: a substantially u-shaped heel chamber having an anterior wall, a curved posterior wall, and medial and lateral sidewalls disposed between the anterior wall and the posterior wall; a forefoot chamber; and a passage connecting the heel chamber and the forefoot chamber, wherein the sole is formed around the cushioning member such that at least a portion of the medial heel sidewall and the lateral heel sidewall are visible.