baber/WOPTO huggingface dataset:
Patent CA-3088180-A1 (CA)
Inventor: BROOKS ALAN RICHARD
IPC: C12N15/90
Filed: 2019-01-11
Abstract: Provided include compositions, methods, and systems for modulating the expression, function, and/or activity of a target gene, for example a blood-clotting protein such as Factor VIII (FVIII), in a cell by genome editing. Also provided include compositions, methods, and systems for treating a subject having or suspected of having a disorder or health condition, e.g., Hemophilia A, employing ex vivo and/or in vivo genome editing.
Patent CA-3089155-A1 (CA)
Inventor: FAUTEUX PHILIPPE
IPC: F16H13/06
Filed: 2019-06-03
Abstract: There is described a multistage friction/traction speed adapter. A first drive can include a plurality of free rollers orbiting around a sun element within a frame, transmitting their orbiting movement to guided rollers which do not contact the sun element or the frame. The guided rollers are driven in the orbiting movement and transmit the rotary movement to a carrier via corresponding pins which engage with the carrier. A second drive can include rollers having radial position variation which is prevented from being transmitted to the carrier by providing accommodation at the pin level, either by providing a bushing around the pins with a bore that is eccentric relative to its outer surface, either by engaging the pins into the carriers in portions thereof which are made more flexible. A friction/traction gear at an angle is also disclosed.
Patent CA-3089182-A1 (CA)
Title: Asymmetrical vacuum-insulated gazing unit
Inventor: SCHNEIDER PIERRE
IPC: E06B3/66
Filed: 2019-01-23
Abstract: The present invention concerns a vacuum insulating glazing unit (10) extending along a plane, P, defined by a longitudinal axis, X, and a vertical axis, Z, comprising: a. a first glass pane (1) having a thickness Z1, and a second glass pane (2) having a thickness, Z2, wherein the thicknesses are measured in the direction normal to the plane, P, and wherein Z1 is greater than Z2 (Z1>Z2); b. a set of discrete spacers (3) positioned between the first and second glass panes and maintaining a distance between the first and the second glass panes; c. a hermetically bonding seal (4) sealing the distance between the first and second glass panes over a perimeter thereof; d. an internal volume, V, defined by the first and second glass panes and the set of discrete spacers and closed by the hermetically bonding seal and wherein a vacuum of pressure less than 0.1 mbar is created, characterized in that, a thickness ratio, Z1/Z2, of the thickness of the first glass pane, Z1, to the thickness of the second glass pane, Z2, is equal to or greater than 1.30 (Z1 / Z2 = 1.30), and in that the second glass pane is made of prestressed glass.
Patent CA-3091265-A1 (CA)
Title: Programmable computer io device interface
Inventor: GALLES MICHAEL BRIAN
IPC: G06F13/28
Filed: 2019-02-19
Abstract: Methods and apparatuses for a programmable IO device interface are provided. The apparatus may comprise: a first memory unit having a plurality of programs stored thereon, the plurality of programs are associated with a plurality of actions comprising updating memory based data structure, inserting a DMA command or initiating an event; a second memory unit for receiving and storing a table result, and the table result is provided by a table engine configured to perform packet match operations on (i) a packet header vector contained in a header portion and (ii) data stored in a programmable match table; and circuitry for executing a program selected from the plurality of programs in response to the table result and an address received by the apparatus, and the program is executed until completion and the program is associated with the programmable match table.
Patent CA-3091463-A1 (CA)
Title: System and method for stabilization of multi-path optical interferometers
Inventor: ISLAM MEHEDI
IPC: G01B9/02
Filed: 2020-08-28
Abstract: A system and a method for phase extraction of a multi-path interferometer, the method comprising generating a reference signal of a coherence length longer than an arm length difference of the multi-path interferometer;  splitting the reference signal into a frequency shifted reference signal and an unshifted reference signal;  recombining the frequency shifted reference signal and the unshifted reference signal into a polarization- and frequency- multiplexed reference signal, and feeding the polarization- and frequency- multiplexed reference signal to the multi-path interferometer; detecting frequency shifted and unshifted output signals of the multi-path interferometer; and determining the interferometer phase from the detected signal.
Patent CA-3092759-A1 (CA)
Inventor: MANCINI GIUSEPPE
IPC: B66B5/00
Filed: 2019-03-01
Abstract: Lift installation (2) including at least one car (13) or platform which can be slidably guided in a shaft (4) along respective guide rails (12) and at least one sensor (21a) for monitoring the shaft (4), wherein the at least one sensor (21 a) comprises at least one inclinometer (11) and/or at least one accelerometer (A1) associated with at least one of the guide rails (12).
Patent CA-3095085-A1 (CA)
Title: Method for increasing the expression level of a nucleic acid molecule of interest in a cell
Inventor: STREITNER CORINNA
IPC: C12N15/82
Filed: 2019-03-26
Abstract: The present invention method for increasing the expression level of a nucleic acid molecule of interest in a cell, preferably a plant cell by means of promoter activating nucleic acid sequences, which are able to increase expression of a nucleic acid molecule of interest in a cell or an organism upon site-specific introduction into a recipient promoter controlling the expression of the nucleic acid molecule of interest. The invention also provides methods to identify such promoter activating elements and methods to introduce them into an organism or a cell to specifically increase the expression of a nucleic acid molecule of interest. Furthermore, the invention also relates to the use of the promoter activating elements to increase the expression of a nucleic acid molecule of interest.
Patent CA-3095261-A1 (CA)
Title: Canola variety 17gn0586r
Inventor: FALAK IGOR
IPC: A01H1/00
Filed: 2020-10-05
Abstract: Provided is a canola variety designated 17GN0586R and seed, plants and plant parts thereof produced from a cross of inbred varieties. Methods for producing a canola variety comprise crossing canola variety 17GN0586R with another canola plant. Methods for producing a canola plant containing in its genetic material one or more traits introgressed into 17GN0586R through backcross conversion and/or transformation, and to the canola seed, plant and plant part produced thereby are described. Canola variety 17GN0586R, the seed, the plant produced from the seed, plant parts and variants, mutants, and minor modifications of canola variety 17GN0586R are disclosed.
Patent CA-3095440-A1 (CA)
Title: Creatine and/or creatinine compositions and related methods
Inventor: NIKOLAIDIS ALEXANDROS
IPC: A23L33/10
Filed: 2019-03-27
Abstract: The disclosure is directed to stable creatine compositions comprising creatinine, compositions comprising creatinine, and methods of using such compositions.
Patent CA-3095661-A1 (CA)
Title: Protection auditive avec lunettes
Inventor: PFANNER ANTON
IPC: A61F11/14
Filed: 2019-03-27
Abstract: L'invention concerne une protection auditive (10) avec des lunettes (12), la protection auditive (10) comprenant au moins un protège-oreille (14, 16) et un serre-tête (18) et les lunettes (12) comprenant deux lunettes (20, 22) pour fixer les lunettes (12) sur la protection auditive (10). Selon l'invention, les lunettes (12) sont fixées à la protection auditive (10) en fixant les branches de lunettes (20, 22) au serre-tête (18).
Patent CA-3099258-A1 (CA)
Inventor: KARMELI RON
IPC: A61B17/064
Filed: 2019-06-12
Abstract: A graft securing system including at least one expandable frame moveable from a collapsed state to an expanded state, and at least one anchor coupled to the frame via an elastic support strut, said anchor including: an anchor base, at least one deflectable prong protruding from said anchor base and having at least one penetration tip and at least one restraining sleeve at least partially slideably moveable along the at least one prong and wherein in the collapsed state, the support strut is biased radially centrally bringing the at least one anchor to point generally axially, parallel to a longitudinal axis of the frame.
Patent CA-3103408-A1 (CA)
Title: Fuel delivery system
Inventor: GRANDA GINO H
IPC: F02M37/04
Filed: 2020-12-21
Abstract: Abstract FUEL DELIVERY SYSTEM       A fuel delivery system having a base, a fuel inlet configured to receive fuel from a secondary fuel supply, a fuel outlet configured to deliver fuel to a machine, a filter assembly and a coalescer configured to filter the fuel, a fuel controller configured to regulate pressure of the fuel that will be delivered to a machine, a boost pump assembly and a main pump assembly configured to pressurize the fuel. Date Recue/Date Received 2020-12-21
Patent CA-3104753-A1 (CA)
Inventor: HESSE ERIC
IPC: C07K16/22
Filed: 2019-06-28
Abstract: The present invention relates to methods and compositions for treating a myopathy in a subject, comprising administering a therapeutically effective amount of a sclerostin antagonist to the subject. The myopathy may be characterized by a loss of skeletal muscle mass, size, strength and / or function. The sclerostin antagonist may be an anti-sclerostin antibody.
Patent CA-3105658-A1 (CA)
Title: Vehicule d'administration a base de retrotransposon et ses procedes d'utilisation
Inventor: SCHAFFER DAVID V
IPC: C12N15/52
Filed: 2019-07-11
Abstract: La présente invention concerne un système d'administration de gènes, comprenant : a) un polypeptide R2 de rétrotransposon R2, ou un premier acide nucléique comprenant une séquence nucléotidique codant pour le polypeptide R2 ; et b) un acide nucléique comprenant une séquence nucléotidique hétérologue codant pour un ou plusieurs produits géniques hétérologues, la séquence nucléotidique hétérologue étant flanquée d'une région non traduite (UTR) 3' de rétrotransposon R2 et d'une UTR 5' de rétrotransposon R2, et la séquence nucléotidique hétérologue possédant une longueur d'au moins 200 nucléotides. La présente invention concerne un procédé d'administration d'un ou plusieurs produits géniques d'intérêt à une cellule eucaryote, le procédé comprenant la mise en contact de la cellule avec le système de véhicule d'administration de gène.
Patent CA-3108023-A1 (CA)
Inventor: BAKER RANDY
IPC: G10D3/147
Filed: 2021-02-03
Abstract: The invention relates to the field of music. The problem this invention solves is that an individual with only one functioning hand is unable to hold the steel for a steel guitar in their other hand. It is the steel that varies pressure on various strings to vary the notes that are played with the functional hand and make the steel guitar functional for music. This invention solves that problem through the addition of the rails on either side of the strings and an attached yoke assembly with the damper spring plate that enables differential pressure to be applied to the strings using an artificial hand or a hand with a limited ability to grasp objects.
Patent CA-3108186-A1 (CA)
Inventor: HOPKINS BRIAN T
IPC: A61K31/506
Filed: 2013-06-07
Abstract: ABSTRACT The present invention provides compounds of Formula f: a F cAN (-44, H F F N F )-.eN ) and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same. Uses for the compounds and compositions to treat autoimmune disorders, inflammatory disorders, and cancers are also provided. Date Recue/Date Received 2021-02-04
Patent CA-3108511-A1 (CA)
Title: Support skirt for coking drum
Inventor: SCANDROLI TONY
IPC: C10G9/04
Filed: 2019-04-12
Abstract: An apparatus for improving thermal-mechanical stress resistance in a delayed coking drum having a drum shell. The apparatus includes a support skirt section configured to mount to and to assist in supporting the coking drum above a ground surface. A joining edge joins the support skirt section to an exterior portion of the drum shell. A T-shaped slot is formed in the support skirt section and is located proximate the joining edge. The T-shaped slot may be formed by a vertical slot portion and a horizontal slot portion joined together as a single slot.
Patent CA-3110543-A1 (CA)
Inventor: SLY ADAM
IPC: F42B30/00
Filed: 2021-02-26
Abstract: An explosive delivery system for avalanche control, including a flying drone with remote-control components; a barrel assembly (at times referred to as a DEDS barrel or payload assembly); an explosive payload; and a control unit
Patent CA-3112446-A1 (CA)
Inventor: BROACH ANITA T
IPC: B29C67/00
Filed: 2019-09-11
Abstract: Solid-state additive manufacturing methods for compounding conductive plastic compositions, fabrication of conductive plastic parts and conductive coatings, and plastic recycling are disclosed. Electrically conductive or thermally conductive plastic compositions are compounded and subsequently printed with the solid-state additive manufacturing system. The solid-state fabricated compositions, parts and coatings can also be manufactured to be both thermally and electrically conductive. Solid-state plastic waste recycling methods are also disclosed where various plastic waste materials and shapes are solid-state processed. The plastic waste can be mixed with virgin plastic material or mixed with other types of materials such as metals, ceramics or their combination. The waste plastic feedstock is reinforced with different types of reinforcing particles or fibers, or various additives are added for improving properties of the final deposits.
Patent CA-3112770-A1 (CA)
Title: Membranes for gas separation
Inventor: HO W S WINSTON
IPC: C01B32/158
Filed: 2019-09-16
Abstract: Membranes, methods of making the membranes, and methods of using the membranes are described herein. The membranes can comprise a support layer, and a selective polymer layer disposed on the support layer. The selective polymer layer can comprise a selective polymer matrix and carbon nanotubes dispersed within the selective polymer matrix. The carbon nanotubes can comprise multi-walled carbon nanotubes wrapped in a hydrophilic polymer, such as polyvinylpyrrolidone or a copolymer thereof, such as poly(1-vinylpyrrolidone-co-vinyl acetate). The membranes can exhibit selective permeability to gases. As such, the membranes can be for the selective removal of carbon dioxide and/or hydrogen sulfide from hydrogen and/or nitrogen.
Patent CA-3114020-A1 (CA)
Inventor: BIDRAM FARHANG
IPC: B25J18/00
Filed: 2019-09-24
Abstract: L'invention concerne un appareil manipulateur destiné à fonctionner sur des articles. L'appareil comprend une colonne comportant une partie de montage pour fixer le manipulateur à une base et une partie extensible qui est mobile sur une plage d'extension par rapport à la partie de montage en réponse à une force d'actionnement fournie par un actionneur de colonne. L'appareil comprend également un bras monté sur la partie extensible de la colonne au niveau d'une articulation de bras et pouvant tourner autour de l'articulation de bras en réponse à un couple d'actionnement fourni par un actionneur de rotation de bras. L'appareil comprend en outre un effecteur d'extrémité configuré fonctionnellement pour effectuer une action sur les articles, l'effecteur d'extrémité étant monté au niveau d'une articulation d'effecteur d'extrémité disposée à une extrémité du bras distale par rapport à l'articulation de bras, l'effecteur d'extrémité pouvant tourner autour de l'articulation d'effecteur d'extrémité en réponse à un couple d'actionnement fourni par un actionneur de rotation d'effecteur d'extrémité. La rotation de l'effecteur d'extrémité se produit dans un plan de mouvement d'effecteur d'extrémité et la rotation du bras se produit dans un plan de mouvement de bras, les plans de mouvement respectifs étant sensiblement parallèles l'un à l'autre, et la partie extensible de la colonne est mobile dans une direction perpendiculaire aux plans de déplacement respectifs et la partie extensible de la colonne amène l'articulation de bras à être disposée pour permettre un jeu pour une rotation complète de 360° du bras sur au moins une partie de la plage d'extension de la partie extensible de la colonne afin de fournir une plage de fonctionnement à l'intérieur de laquelle l'effecteur d'extrémité est apte à se déplacer pour fonctionner sur les articles.
Patent CA-3116452-A1 (CA)
Title: Genome editing methods and constructs
Inventor: AURICCHIO ALBERTO
IPC: C12N15/10
Filed: 2019-10-15
Abstract: The present invention relates to a method of integrating an exogenous DNA sequence into a genome of a cell comprising contacting the cell with: a) a donor nucleic acid comprising: - at least one STOP codon and a translation initiation sequence (TIS) or - a ribosomal skipping sequence, and - said exogenous DNA sequence wherein said donor nucleic acid is flanked at 5' and 3' by inverted targeting sequences; b) a complementary strand oligonucleotide homologous to the targeting sequence and c) a nuclease that recognizes the targeting sequence.
Patent CA-3118298-A1 (CA)
Inventor: ROSS JOHN R
IPC: B21D51/40
Filed: 2019-11-05
Abstract: The present invention relates generally to a container that may be sealed and reclosed with a threaded closure. More specifically, the present invention relates to methods of manufacturing a metallic container having an opening with inwardly facing threads. The threads are formed on the metallic container by pressing a neck portion of the metallic container against closure threads of a threaded closure which is inserted at least partially into the opening. The container threads may optionally be formed while the threaded closure is in tension. In this manner, after the container threads are formed, the closure threads can apply a force to the container threads such that the threaded closure is in tension. The container opening may be selectively sealed and reclosed with the threaded closure which releasably engages the container threads. Novel apparatus and methods of sealing metallic containers and forming threads on the metallic containers are also disclosed.
Patent CA-3118314-A1 (CA)
Inventor: SILVER JESSE AMOS
IPC: A61M11/00
Filed: 2019-11-08
Abstract: Selon un aspect, la présente invention concerne un appareil qui peut comprendre une cartouche et un corps de vaporisateur. La cartouche peut comprendre un corps de cartouche définissant un réservoir configuré pour contenir un matériau vaporisable, et un ensemble de vaporisation positionné à l'intérieur du corps de cartouche. Le corps de vaporisateur peut comprendre un réceptacle configuré pour recevoir au moins une partie de la cartouche, et des circuits de commande comprenant au moins un processeur et au moins une mémoire disposée dans le corps de vaporisateur, la ou les mémoires comprenant des instructions qui, lorsqu'elles sont exécutées, provoquent des opérations comportant : le stockage d'un événement indicatif de la détection d'une insertion de la cartouche dans le corps de vaporisateur ; la demande, depuis la cartouche, d'informations de cartouche ; la réception, en réponse à la demande, les informations de cartouche stockées au niveau de la cartouche ; et la configuration, sur la base au moins en partie des informations de cartouche reçues, du dispositif vaporisateur pour vaporiser un matériau vaporisable.
Patent CA-3118316-A1 (CA)
Inventor: OHLSSON HENRIK
IPC: G06N20/00
Filed: 2019-10-31
Abstract: The present disclosure provides systems and methods that may advantageously apply machine learning to accurately manage and predict inventory variables with future uncertainty. In an aspect, the present disclosure provides a system that can receive an inventory dataset comprising a plurality of inventory variables that indicate at least historical (i) inventory levels, (ii) inventory holding costs, (iii) supplier orders, or (iv) lead times over time. The plurality of inventory variables can be characterized by having one or more future uncertainty levels. The system can process the inventory dataset using a trained machine learning model to generate a prediction of the plurality inventory variables. The system can provide the processed inventory dataset to an optimization algorithm. The optimization algorithm can predict one or more inventory management parameters that result in a particular probability of achieving a target service level while minimizing a cost. The optimization algorithm can comprise constraint conditions.
Patent CA-3120993-A1 (CA)
Title: Genetically modified cannabis sativa plants and modified cannabinoid compounds for treatment of substance addiction and other disorders
Inventor: WILLIAMS JONNIE R
IPC: A61P25/32
Filed: 2019-02-11
Abstract: A method of increasing the cannabinoid levels in a genetically modified Cannabis sativa plant includes genetically modifying the plant to induce the overexpression of the gene that controls the expression of tetrahydrocannabinolic acid (THCA) synthase and/or cannabidiolic acid (CBDA) synthase. The overexpression of THCA synthase and CBDA synthase catalyzes an increased synthesis of cannabigerolic acid to tetrahydrocannabinolic acid and cannabidiolic acid, as well as the cannabinoids (3aR)-2,4,4-trimethy1-7-penty1-3,3a,4,9b- tetrahydrocyclopenta[c]chromen-9- - ol and 2-((1 R,5R)-3-methy1-5 -(prop- 1 -en-2-yl)cyclopent-2-en- 1 -y1)-5-p entylbenzene- 1 ,3-d iol. Pharmaceutical compositions comprising the modified cannabinoids produced by the transgenic Cannabis sativa plant or prepared synthetically are used to treat various diseases and conditions.
Patent CA-3121780-A1 (CA)
Title: Method for adjusting the amount of dilution water of a sizing composition, and corresponding calculcating unit
Inventor: PLATON DIANA
IPC: G01N33/38
Filed: 2019-12-19
Abstract: The invention relates to a method for manufacturing a mat of mineral fibres (F), wherein the fibres (F) are formed and a sizing composition obtained from mixing a binder composition with dilution water is applied to the fibres (F), the fibres impregnated with the sizing composition are collected on an open-worked receiving device (52) provided with a fibre-receiving surface and, under the surface, at least one suction sheath (54), and the mat is thermally treated. The method according to the invention comprises a step of determining an optimal amount of dilution water according to the humidity of the air on the fiberising station (12), the humidity of the air drawn in and the flow of air drawn into the at least one suction sheath (54), and the amount of water desired in the mat at the outlet of the receiving chamber (50), and a step of adjusting the amount of dilution water according to the optimal amount thus determined.
Patent CA-3126697-A1 (CA)
Title: Use of renewable energy in olefin synthesis
Inventor: WARD ANDREW MARK
IPC: C10G9/24
Filed: 2020-01-14
Abstract: An olefin synthesis plant comprising: a feed pretreatment section configured to pretreat a feed stream; a pyrolysis section comprising one or more pyrolysis reactors configured to crack hydrocarbons in the feed stream in the presence of a diluent to produce a cracked gas stream; a primary fractionation and compression section configured to provide heat recovery from and quenching of the cracked gas stream; remove a component from the cracked gas stream; and compress the cracked gas stream, thus providing a compressed cracked gas stream; and/or a product separation section configured to separate a product olefin stream from the compressed cracked gas stream, wherein the olefin synthesis plant is configured such that, relative to a conventional olefin synthesis plant, more of the energy and/or the net energy required by the olefin synthesis plant and/or one or more sections thereof, is provided by a non-carbon based and/or renewable energy source and/or electricity.