baber/WOPTO huggingface dataset:
Patent IL-101167-A0 (IL)
Title: Platinum(ii)complexes,processes for the preparation thereof,and pharmaceutical compositions containing the same
IPC: A61K31/555
Filed: 1992-03-06
Abstract: Disclosed herein are novel platinum(II) complexes having a potent anti-tumor activity which are represented by the formula (1),    <IMAGE>  (1)   <IMAGE>  (a)   <IMAGE>  (b)  wherein R1 and R2, which may be the same or different, are a hydrogen atom or a C1-4 alkyl group, respectively, or jointly form a cycloalkane group together with the carbon atom attached thereto; two Xs jointly form a group represented by formula (a) or (b) wherein, R3 is a hydrogen atom or a methyl group; R4 and R5, which may be the same or different, are a hydrogen atom or a C1-4 alkyl group, respectively, or jointly form a cyclobutane together with the carbon thereto; and the absolute configurations at the respective chiral centers in the 4,5-bis(aminomethyl)-1,3-dioxolane moiety are (4R,5R) or (4S,5S); processes for the preparing the same; and their use for treating animal or human cancer. Further, disclosed herein are novel intermediates useful for the preparation of the platinum(II) complexes and processes for preparing said intermediates.
Patent IL-106451-A0 (IL)
Title: Taste-masking composition of bitter pharmaceutical agents
IPC: A61K9/20
Filed: 1993-07-22
Abstract: A pharmaceutical composition having reduced bitterness consisting of a bitter pharmaceutical agent, a taste-masking component and a pharmaceutically acceptable carrier. The taste-masking component is an alkaline earth oxide, an alkaline earth hydroxide or an alkaline hydroxide and does not interfere with the activity of the pharmaceutical agent.
Patent IL-109866-A0 (IL)
Title: Crystalline 3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine (+) l-hydrogentartrate, its preparation and pharmaceutical compositions containing it
IPC: C07D417/04
Filed: 1994-06-02
Abstract: The invention provides crystalline 3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine (+) L-hydrogentartrate, its preparation and use as a therapeutic agent.
Patent IL-119551-A0 (IL)
Title: Straight or branched 9-[(haloacyl) amido]-7-(substituted)-6- demethyl-6-deoxytetracycline intermediates
IPC: C07D203/08
Filed: 1996-11-03
Abstract: The invention provides a novel method for producing compounds of the formula I: <CHEM> wherein X and R are defined in the specifications. The invention also provides a method for making intermediates useful to produce the compounds of formula I. Utilizing a common intermediate, the novel method efficiently produces compounds of the formula I.
Patent IL-124015-A0 (IL)
Title: Pharmaceutical compositions comprising a protein
IPC: A61K38/18
Filed: 1998-04-08
Abstract: Pharmaceutical compositions comprising erythropoietin are provided for treatment of cancer, particularly for treatment of multiple myeloma. Erythropoietin was found to be effective for inhibition of tumor growth, triggering of tumor regression, stimulation of the natural immunological defense against cancer and/or inhibition of cancer cell metastasis.
Patent IL-124953-A0 (IL)
Title: Cosmetic self-tanning agent having a sunscreen effect
IPC: A61Q17/04
Filed: 1997-01-17
Abstract: PCT No. PCT/DE97/00119 Sec. 371 Date Jun. 26, 1998 Sec. 102(e) Date Jun. 26, 1998 PCT Filed Jan. 17, 1997 PCT Pub. No. WO97/25970 PCT Pub. Date Jul. 24, 1997The invention concerns a cosmetic self-tanning agent based on dihyroxyacetone and having a sunscreen effect. The object of the invention is to prepare an agent in which the self-tanning effect occurs shortly after application and over a long period of time, and in which a plurality of color shades can be obtained without additional color components. According to the invention, the agent contains: specific portions of one or a plurality of UV filters selected from the group comprising octylsalicylate, octylmethoxycinnamate and benzophenone-3 and their mixtures; dihydroxyacetone (DHA) in a liposomal carrier system and additionally unencapsulated DHA; an antioxidant selected from the group comprising tocopherol, ascorbic acid, calendula extract and a mixture thereof; a moisturizer selected from the group comprising aloe vera, phospholipids, phospholipid mixtures, sodium hyaluronate, glycerol and mixtures thereof; and cosmetic carrier substances and additives.
Patent IL-125107-A0 (IL)
Title: Derivatives of antibiotic ge2270 factors c2a, d2 and e
IPC: C07K5/078
Filed: 1997-02-12
Abstract: PCT No. PCT/EP97/00628 Sec. 371 Date Jun. 29, 1998 Sec. 102(e) Date Jun. 29, 1998 PCT Filed Feb. 12, 1997 PCT Pub. No. WO97/30078 PCT Pub. Date Aug. 21, 1997Mono- or di-substituted derivatives of GE2270 factors C2a, D2 and E of general formula (I), wherein W represents a moiety of formula (a), (b) or (c), R1 and R2 representing a variety of substituents, X1 is methyl, X2 is a -CH2-W1 moiety and X3 is methylamino or amino, or X1 is a -CH2-W1 moiety, X2 is methoxymethylene and X3 is methylamino, with the proviso that when X3 is amino, then W must be 2-(aminocarbonyl)-pyrrolidinyl; with the further proviso that when W is 2-(aminocarbonyl)-pyrrolidinyl, then W1 cannot be hydroxy; and the pharmaceutically acceptable salts thereof. The mono- or di-substituted derivatives of antibiotic GE 2270 of formula (I) are antimicrobial agents mainly active against gram positive bacteria.
Patent IL-128164-A0 (IL)
Title: Polisocyanate-based polymer comprising metal salts and preparation of metal powders therefrom
IPC: C08K3/00
Filed: 1997-07-21
Abstract: A polyisocyanate-based polymer having dispersed therein a metal salt, obtained by reacting an organic polyisocyanate with an aqueous composition of a metal salt. The polymer comprises the metal salt in an amount of from at least 10 weight percent based on total weight of the dry salt with the weight of the polyisocyanate-based polymer including salt therein. The polymer on calcination provides a metal-containing powder having an average particle size of 1 micrometer or less. Such metal-containing powders are of value in the preparation of industrial catalysts, ceramics, electronic components, or as fillers in plastics, paints, or cosmetics.
Patent IL-138815-A0 (IL)
Title: Arrangement and method to apply diffusing wave spectroscopy to measure the properties of multi-phase systems as well as the changes therein
IPC: G01J3/44
Filed: 1999-04-06
Abstract: Method and arrangement for measuring the properties of multi-phase systems as well as the changes therein, such as changing interactions between particles in a solution, the arrangement having laser means (1) for producing a laser beam (2), a single source fibre (5) having a first end arranged for receiving the laser beam (2) and a second end arranged for emitting laser light in a multi-phase system (7), at least one detector fibre (8(1), 8(2), ...) arranged for detecting the laser light after being scattered by the multi-phase system (7), processing means arranged for receiving an output signal from the at least one detector fibre and for calculating predetermined parameters with respect to the multi-phase system (7), any one of the at least one detector fibre (8(1), 8(2), ...) being located at predetermined locations with respect to the second end of the source fibre (5). <IMAGE>
Patent IL-143047-A0 (IL)
Title: Assay for phosphatase-targeting toxins
IPC: G01N33/553
Filed: 1999-11-11
Abstract: The invention provides an assay method for determining phosphatase targeting toxins which inhibit protein phosphatases comprising contacting a solid support having an immobilized ligand immobilized thereon with: (i) a sample suspected of being contaminated with toxin and (ii) a non-immobilized ligand, wherein said immobilized ligand is capable of generating directly or indirectly detectable signal when uncomplexed, when complexed by said toxin, when complexed by a complex of said toxin and said non-immobilized ligand or when complexed by said non-immobilized ligand or said non-immobilized ligand is capable of generating a directly or indirectly detectable signal when uncomplexed or when complexed, separating a bound fraction from a non-bound fraction; and directly or indirectly determining the non-immobilized ligand bound to the immobilized ligand (the bound fraction) or non-complexed in aqueous solution (the non-bound fraction).
Patent IL-146920-A0 (IL)
Title: Propelling device for a projectile in a missile
IPC: F42B15/00
Filed: 2000-06-02
Abstract: A propelling device for a projectile that is lying in a standby position within a rocket motor in a missile. The projectile is translated with respect to the rocket motor by means of a pyrotechnic charge before the rocket motor is ignited. The projectile is lying within a translation tube centrally located in the rocket motor. The projectile comprises a power piston in the rear end thereof. The power piston encloses a pyrotechnic power charge and a pyrotechnic squib. The translation tube is sealable closed behind the power piston and forms a closed expansion chamber for the pyrotechnic charges which, by ignition, generate gas pressure that activates the power piston and thus propels the projectile forward within the translation tube.
Patent IL-175192-A0 (IL)
Title: Display of catheter tip with beam direction for ultrasound system
Filed: 2006-04-25
Abstract: A display of a catheter tip having a beam direction for an ultrasonic system is provided to reduce an operation time of a surgeon by using a three-dimensional ultrasonic image in performing a complex operation. A catheter(28) includes a position sensor and an ultrasonic imaging sensor. A positioning processor is connected to the catheter(28) to determine position information of a part of the catheter(28) based on an electrical signal transmitted by the position sensor. An image processor(42) is operationally connected to the catheter(28), the positioning processor, and a display unit(44). The position sensor transmits an electrical signal which represents position information of a part of the catheter(28) within a patient body. The ultrasonic imaging sensor transmits ultrasonic energy to an object within the patient body, and receives an ultrasonic reflective sound reflected from the object within the patient body. The image processor(42) displays a catheter icon on the display unit(44) in the same orientation as an orientation of the catheter(28) within the patient body based on the position information induced from the position sensor. The image processor(42) generates an ultrasonic image of the object based on the signal transmitted by the ultrasonic sensor. The image processor(42) displays the generated ultrasonic image in real-time on the display(44) in the same orientation as an orientation of the catheter(28) within the patient body based on the position information induced from the position sensor.
Patent IL-176804-A0 (IL)
Title: Flying object for observing the ground
IPC: F42B12/36
Filed: 2006-07-12
Abstract: The machine has a lifting and displacing propulsive unit (3) and an altitude propulsive unit (5) which are placed on both sides of centre of gravity of the machine. The position of the centre of gravity remains fixed, during the combustion of propulsive loads of the propulsive units. The unit (3) has a mass less than that of the unit (5) and close to the centre of gravity of the machine.
Patent IL-178490-A0 (IL)
Title: Treatment of diseases
IPC: C07K16/28
Filed: 2006-10-05
Abstract: The present disclosure relates to a medicament for the treatment of disorders. In particular, but not exclusively, the invention relates to medicaments for restoring or improving neural transmission in damaged nerve cells. Certain aspects of the disclosure relate to medicaments for treatment of non-demyelinating neural disorders. Other aspects of the disclosure relate to medicaments for the treatment of demyelinating disorders.
Patent IL-184574-A0 (IL)
Title: Production of hetero-oligomeric proteins in plants
Filed: 2007-07-12
Abstract: Process of producing in a plant, in plant tissue, or in plant cells a hetero-oligomeric protein comprising at least a first and a second protein subunit, said process comprising expressing in plant cells at least said first and said second protein subunit by  (i) providing to said plant, said plant tissue or said plant cells a plus-sense single-stranded RNA viral vector encoding at least said first and said second protein subunit or  (ii) providing to said plant, said plant tissue or said plant cells a first and a second plus-sense single-stranded RNA viral vector, said first viral vector encoding at least said first protein subunit, said second viral vector encoding at least said second protein subunit, whereby at least said first viral vector and said second viral vector are non-competing viral vectors.
Patent IL-186207-A0 (IL)
Title: Varying properties along lengths of temperature limited heaters
Filed: 2007-09-24
Abstract: A heating system for a subsurface formation is described. The heating system includes a first heater, a second heater, and a third heater placed in an opening in the subsurface formation. Each heater includes: an electrical conductor; an insulation layer at least partially surrounding the electrical conductor; and an electrically conductive sheath at least partially surrounding the insulation layer. The electrical conductor is electrically coupled to the sheath at a lower end portion of the heater. The lower end portion is the portion of the heater distal from a surface of the opening. The first heater, the second heater, and the third heater are electrically coupled at the lower end portions of the heaters. The first heater, the second heater, and the third heater are configured to be electrically coupled in a three-phase wye configuration.
Patent RO-126655-A0 (RO)
Title: Chassis for off-road vehicles and process for carrying out the same
Inventor: CIOBANU MIHAI MĂRŢIŞOR
IPC: B62D21/02
Filed: 2011-04-11
Abstract: The invention relates to a chassis for off-road vehicles made of flat sheet metal and to a process for carrying out the same, the chassis having a plane arrangement, where h = 0 or a spatial arrangement where h ≠ 0 in the vertical plane, depending on the vehicle characteristics. According to the invention, the chassis comprises a left girder (1), a right girder (2) and various cross-bars (3), each girder having two covers (4) and two side members (5), either welded or assembled by riveted plates (6), so as to form a rectangular tubular structure inside of which there can be placed the wiring (7), the piping (8) and the final part of the exhaust installation (12), after which the inside of said structure is filled with polyurethane foam (9). The process claimed by the invention starts by cutting the side members (5) and covers (4) with a numerically-controlled tool with water jet, laser or plasma, simultaneously with making all the holes required for riveting, the holes (11) for the fastening bushings and for passing the wiring (7), the piping (8) and the final part of the exhaust installation (12), bending the semiproduct with a program-controlled machine in order to obtain the final outline given by the h≠ 0 size and corrosion-protecting it by filling with polyurethane foam (9), followed by assembling the covers (4) and side members (5) by riveting or welding.
Patent RO-127992-A0 (RO)
Title: Generic solution for connection to digital encryption devices
Inventor: POPESCU IULIAN VASILE
IPC: G06F21/24
Filed: 2012-06-13
Abstract: The invention relates to an application able to connect itself to any type of encryption device for issuance of digital certificates or for temporal marking of documents. According to the invention, the application communicates with a computer specialized in cryptographic activities () (Hardware Security Module) where there are stored certificates and private keys of a certification authority, the certification application () (Certification Authority) requests to the specialized computer () the certificates to be signed only when they are validated by an operator of the authority while, for temporal marking services, after saving a client's request, the application () creates a temporal marking packet and sends it to be signed to the specialized computer () to which it connects itself.
Patent RO-128740-A0 (RO)
Title: Process and composition for preparing bioactive laminated composites
Inventor: PASLARU ELENA
IPC: B65D85/72
Filed: 2013-02-07
Abstract: The invention relates to a process for preparing a composite with antimicrobial activity used for packing food products. According to the invention, the process consists in activating polyethylene films in corona discharge plasma, immersing them into a solution of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide and N-hydroxysuccinimide in a molar ratio of 7:1 or N, N''-carbonyldiimidazole of 20 mM concentration in ethanol, after which the thus activated films are coated by electrospraying with a mixture solution of 2.5% chitosan and 0.5% vitamin E in acetic acid, wherefrom there result a laminated composite having an inhibiting effect upon gram-negative and gram-positive bacteria.
Patent RO-131050-A0 (RO)
Title: Prefabricated modular elements for constructions
Inventor: ADOBRIŢEI CIPRIAN CONSTANTIN
IPC: F24B5/02
Filed: 2015-09-21
Abstract: The invention relates to prefabricated modular elements which can be used in constructions, for building walls, floors and roofs. According to the invention, the modular elements are manufactured by attaching a core consisting of two types of alternating plates, one intermediary plate (2) and one insulating plate (3), between two main plates (1), stiffening them by using some stiffening struts (4), and fixing on the main plates (1) some small metal plates (7) which make the connection between the elements by using some screws (8) and on which some finishing plates (6) are also attached, by means of some screws (9), after some electrical and sanitary plumbing installations (11) have been previously mounted through the space left between the insulating plates (3) and the finishing plates (6).
Patent IE-910588-A1 (IE)
Title: Polymers
IPC: C08F218/04
Filed: 1991-02-20
Abstract: The invention provides a co-polymer having a hub portion from which radiate from 3 to 8 arms where the hub portion is the residue of a tri-functional to octa-functional thiol and each arm is an addition polymer comprising structural units and functional units that are mutually compatible, the functional units including crosslinking substituents capable of undergoing a crosslinking reaction with a crosslinking agent or the same or a complimentary substituent in functional units in another molecule of the same polymer and optionally compatible auxiliary functional units that contain wetting groups.
Patent IE-910632-A1 (IE)
Title: Improvements relating to collection devices
IPC: A01G1/12
Filed: 1991-02-25
Abstract: The present specification discloses a collection device comprising an elongate duct (3) for conveying loose material towards a downstream region thereof from a collection mouth (7) at an upstream end thereof. An air outlet (23,25) is disposed adjacent the collection mouth (7) and arranged to in use direct an air flow transversely to the longitudinal axis of the duct over a curved, generally convex flow control surface (27,29) of the collection mouth (7) such that at least a portion of said air flow follows said curved surface (27,29) and is directed downstream within said duct. <IMAGE>
Patent IE-910777-A1 (IE)
Title: Improvements in and relating to magnetic resonance imaging
Inventor: KUCHARCZYK JOHN
IPC: G01R33/465
Filed: 1991-03-08
Abstract: The invention provides a method of monitoring the vasodilatory or vasoconstrictive effects of a physiologically active substance administered to a human or non-human animal body, said method comprising the steps of: administering said substance into said body; administering into the systemic vasculature of said body a contrast enhancing amount of an intravascular paramagnetic metal containing magnetic resonance imaging contrast agent; subjecting said body to a magnetic resonance imaging procedure capable of generating from magnetic resonance signals from said body a series of temporally spaced images of at least a part of said body into which said agent passes, said procedure being a fast imaging procedure having an image acquisition time of less than five seconds; and detecting temporal variations in said signals or images whereby to monitor the vasoconstriction or vasodilation induced by said substance.
Patent LU-75962-A1 (LU)
Inventor: SCHELKMANN WILHELM
IPC: B29D30/58
Filed: 1976-10-08
Abstract: METHOD OF RENEWAL OF THE TREAD ON A WORN PNEUMATIC OF SOLID RUBBER TYRE The invention is concerned with a method of renewal of the tread of a worn pneumatic or solid rubber tyre.  A layer of bonding rubber is applied to the prepared body of the tyre and a prefabricated rubber tread ring is applied.  Gaseous inclusions between the applied layers are avoided or led away and the resulting blank is heated in an autoclave for vulcanizing the bonding rubber.  The tread rins, which on its underside exhibits a rough face of projections and recesses forming a net work of passages, produced in a press mould simultaneously with the production of the tread and kept fit for bonding, is applied to the body coated with the layer of bonding rubber and any gaseous inclusions are led away out of the layers by application of reduced pressure, where upon the lateral outlet openings from the super imposed layers are sealed off, and/or by squeezing out by means of the  exertion of mechanical pressure on the tread.
Patent LU-87468-A1 (LU)
Title: Water intake unit esp. for dammed reservoir - comprises frame with pivoted pipe adjustable by winch to vary level of intake end
Inventor: GUY HANSEN
IPC: E03B3/04
Filed: 1989-03-06
Abstract: A water intake unit, for use especially in a natural or artificial reservoir held back by a dam to draw off water for treatment to produce drinking water, consists of a pipe (10) which is mounted on a frame standing in the water and able to pivot about a horizontal axis. The free end of the pipe is equipped with a strainer (12), and the pivoted end has two bearings (30). The movement of the pipe - so that the intake end remains at a certain depth in the water - is carried out by means of a winch (5) and cable (52). The supporting frame is made from stainless steel and is set in foundations on the bed of the reservoir, and its upper end, above the highest water level, has a cabin containing the winch and its equipment.
Patent MA-22045-A1 (MA)
Inventor: A R BLANCO
IPC: B65D33/10
Filed: 1991-01-18
Abstract: Paper bag with integral carrying device consisting of two main panels (2,1), two side panels (3,4), a bottom panel and a top panel, whereby the integral carrying device is formed by folding over extensions of said main panels and by punching a carrying hole (18) in said folded-over extensions of said main panels. <IMAGE>
Patent MA-25092-A1 (MA)
Title: Brique pour pose a sec
Inventor: TONY J AZAR
IPC: E04B2/06
Filed: 2000-04-03
Abstract: BLOC DE CONSTRUCTION POUR EMPILAGE AVEC D'AUTRES BLOCS DE CONSTRUCTION DU MeME TYPE POUR FABRIQUER UN MUR.LE BLOC DE CONSTRUCTION  POSSèDE DES SURFACES SUPÉRIEURE, INFÉRIEURE, ANTÉRIEURE 1,  POSTÉRIEURE 2  ET D'EXTRÉMITÉ. LES SURFACE ANTÉRIEURE 1  ET POSTÉRIEURE 2 SONT SENSIBLEMENT PLANES. LA SURFACE SUPÉRIEURE PRÉSENTE UNE VERVURE 3  ET LA SURFACE INFÉRIEURE.  LES EXTRÉMITÉSS SONT ENTAILLÉS 7,8  DE MANIE à SE CHEVAUCHER ET POUR DONNER L'APPARENCE D'UN MUR EN BRIQUES.
Patent MA-26288-A1 (MA)
Inventor: BEN-YEHOSHUA SHIMSHON
IPC: A23L3/3544
Filed: 2004-03-30
Abstract: The present invention deals with a microbiocidal aqueous formulation comprising: (i) an effective amount of at least one essential oil component, or derivatives thereof, said derivatives thereof obtained by exposure to light or by oxidation, or mixtures thereof; and (ii) at least one additional stabilizer selected from the group consisting of ethanol in an amount of from 10% to about 50%, an emulsifier, an antioxidant, or an encapsulating agent. The invention is further directed to a method for inhibiting microbial development using said microbiocidal aqueous formulation.