baber/WOPTO huggingface dataset:
Patent CA-2769663-A1 (CA)
Title: Methods and compositions for detection of a pathogen, disease, medical condition, or biomarker thereof
Inventor: ARAD DORIT
IPC: C12Q1/34
Filed: 2009-07-28
Abstract: Provided are methods for detecting the presence or absence of a pathogen, disease, or medical condition, or biomarker thereof, using an enzymatic activity assay. In one embodiment, the method provided utilizes competitive inhibition of an ezyme for detecting a pathogen, disease, or medical condition, or biomarker thereof, in a subject. The method comprises providing a biological sample from the subject that may or may not contain an endogenous substrate. A test reaction is provided by contacting the biological sample with an enzyme indicative of the biomarker of a pathogen, disease, or medical condition and a substrate comprising a signaling moiety. The enzyme modifies the endogenous substrate and the substrate comprising the signaling moiety. Modification of the substrate comprising the signaling moiety by the enzyme produces a signal from the signaling moiety. Data from a control reaction comprising the enzyme and the substrate comprising the signaling moiety is further provided. The signal produced by the signaling moiety in the test reaction is detected. The presence of the biomarker of the pathogen, disease, or medical condition is indicated by a difference caused by the presence of the endogenous substrate in the biological sample between the signal produced in the test reaction and the data from the control reaction. In another embodiment, there is provided a method of detecting the presence or absence of enzymatic activity in a biological sample indicative of a pathogen, disease, or medical condition, or biomarker thereof, in a subject. The method comprises contacting a biological sample obtained from a subject that may or may not contain an enzyme with a substrate of the enzyme to be detected. The substrate comprises a signaling molecule such that when the enzyme is present in the biological sample, the enzyme modifies the substrate and the signaling moiety emits a signal, indicating the presence of a pathogen, disease, or a medical condition, or a biomarker thereof, in the subject.
Patent CA-2771499-A1 (CA)
Inventor: BERGMANN BERND
IPC: G01N9/24
Filed: 2012-03-16
Abstract: In a method for calibrating at least one detector array formed by a plurality of detectors that is exposed to a high-energy, fan-shaped expanding radiation emanating from an approximately point-like energy source, serving the penetration of a material for measuring physical properties due to the absorption capacity of the material, it is provided that at least two in each case homogeneously formed calibration bodies,whose gradually differing absorption is designed in a way that the absorption capacity of the one calibration body is lower and the one of the other calibration body is higher than the absorbance capacity of the material to be measured, are successively entered into the beam path, and that for each detector element in the detector array and for each calibration body the absorption capacity, i.e., the intensity of the radiation, is measured, and the absorbance capacity of each calibration body is assigned to a known property of these calibration bodies and that the absorption capacity is interpolated in sections between these known properties.
Patent CA-2773003-A1 (CA)
Title: Orally disintegrating pharmaceutical dosage form containing aripiprazole
Inventor: KALYANKAR PARSHWAKUMAR V
IPC: A61K9/16
Filed: 2010-09-09
Abstract: The present invention relates to an orally disintegrating dosage form containing aripiprazole. The formulation of the invention shows a fast disintegration.
Patent CA-2773106-A1 (CA)
Inventor: LAMONTAGNE BRADLEY ALLAN
IPC: E21B7/28
Filed: 2012-03-26
Abstract: A well bore reamer has an elongated body for coupling between members of a well string, a first set of cutting elements on the body at a fixed position, a second set of cutting elements on a sleeve closing around a sleeve carrying portion of the elongated body. The sleeve is slidable along a longitudinal axis of the body and rotatable thereabout. A lower clutch mechanism operates between the sleeve and the elongated body at a bottom end of the body's sleeve carrying portion to block rotation of the sleeve relative to the elongated body in a predetermined direction about the longitudinal axis under sliding of the sleeve into a lowered position adjacent said bottom end of the sleeve carrying portion.
Patent CA-2773555-A1 (CA)
Inventor: KOSLEY RAYMOND WALTER JR
IPC: A61K31/519
Filed: 2010-09-14
Abstract: The present invention relates to a series of substituted dihydro benzocycloalkyl-oxymethyl oxazolopyrimidinones of formula (I) as defined herein. This invention also relates to methods of making these compounds including novel intermediates. The compounds of this invention are modulators of metabotropic glutamate receptors (mGluR), particularly, mGluR2 receptor. Therefore, the compounds of this invention are useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of central nervous system disorders (CNS), including but not limited to acute and chronic neurodegenerative conditions, psychoses, cognition deficit disorders, convulsions, anxiety, depression, migraine, pain, sleep disorders and emesis.
Patent CA-2774437-A1 (CA)
Inventor: KHOLAIF AHMAD MOHAMMAD MOHAMMAD
IPC: H04L45/85
Filed: 2012-04-12
Abstract: Techniques for efficient scanning for WLANs based on mobile device velocity are described. In one illustrative example, a mobile device identifies whether its velocity is less than or greater than a threshold value. While it is identified that the velocity of the mobile device is less than the threshold value, the mobile device scans to search for one or more WLANs identified in a first subset of WLAN profiles (e.g. "stationary" WLANs). While it is identified that the velocity of the mobile device is greater than the threshold value, the mobile device scans to search for the one or more WLANs identified in a second subset of WLAN profiles (e.g. "mobile" WLANs).  Advantageously, a suitable WLAN may be more efficiently identified with use of a technique which reduces power consumption of the mobile device.
Patent CA-2775065-A1 (CA)
Inventor: MASUDA TAKEYOSHI
IPC: C30B29/36
Filed: 2011-05-19
Abstract: Disclosed are: a silicon carbide substrate which is capable of reducing the production cost of a semiconductor device that uses the silicon carbide substrate; and a method for producing the silicon carbide substrate. Specifically disclosed is a method for producing an SiC bonded substrate, which comprises: a step (S10) of preparing a plurality of single crystal bodies that are composed of silicon carbide (SiC); a step (S20) of forming an assembly; a step (S30) of bonding the single crystal bodies with each other; and a step (S60) of slicing the assembly. In the step (S20), an assembly of single crystal bodies is formed by aligning a plurality of SiC single crystal ingots with an Si layer containing silicon (Si) being interposed between adjacent single crystal ingots. In the step (S30), at least a part of the Si layer is changed into silicon carbide by heating the assembly and adjacent SiC single crystal ingots are bonded with each other by the portion which is changed into silicon carbide in the Si layer. In the step (S60), the assembly wherein the SiC single crystal ingots are bonded with each other is sliced.
Patent CA-2775080-A1 (CA)
Inventor: HSU JU-LAN
IPC: H04W52/02
Filed: 2010-09-20
Abstract: A method and system for wireless communication over a wireless communication medium is provided. A schedule is generated which indicates when a wireless communication station may enter a power saving state in an announcement time (AT) period, based on an idle timeout interval in the AT period. The AT period comprises a period after a beacon transmission in a beacon interval.
Patent CA-2775725-A1 (CA)
Inventor: GENTRY STEVEN RICHARD
IPC: E21B7/28
Filed: 2010-09-30
Abstract: Expandable reamers for enlarging wellbores include a tubular body and one or more blades configured to extend and retract. A sleeve member within the tubular body has open ends to allow fluid to flow therethrough. A fluid port extends through a wall of the sleeve member. A restriction member within the sleeve is movable between first and second positions. In the first position, fluid flow through the downhole end of the sleeve is generally unimpeded, and fluid flow through the fluid port is generally impeded. In the second position, fluid flow through the downhole end of the sleeve member is generally impeded, and fluid flow through the fluid port is generally unimpeded. The restriction member may be configured to move responsive to changes in the rate of fluid flow through the sleeve member. Methods of using such reamers are also disclosed.
Patent CA-2775852-A1 (CA)
Inventor: DITTRICH TILO
IPC: B25C1/08
Filed: 2012-05-02
Abstract: The invention relates to a fastener-setting tool with a combustion chamber (12), in which an electrically driven device (14) for generating turbulence or for flushing the combustion chamber (12) is arranged, and with an electrical energy storage device (24). In order to further simplify the operation [of] a fastener-setting tool, the electrical energy storage device (24) is configured for operation with non-rechargeable primary cells.
Patent CA-2776556-A1 (CA)
Inventor: BOUVERET NICOLAS
IPC: B29C45/14
Filed: 2010-10-01
Abstract: A food container for microwave use comprises at least one compartment for receiving a food item, the container portion having a structural wall defining the lateral sides of the container portion. The structural wall is made of a polymer. A label is secured to the structural wall and covers continuously the lateral sides of the container portion. The label has an inner surface against the structural wall and an outer surface oriented away from the structural wall. The label comprises a substrate defining the outer surface of the label and a metallic ink defining partly the inner surface of the label. The metallic ink defines a continuous coating on the label with openings. The openings have a selected dimension to allow some microwaves to pass therethrough to reach the food item m the compartment. A method for fabricating a food container for microwave use is also provided.
Patent CA-2777233-A1 (CA)
Title: Compositions and methods for treating varicose veins
Inventor: GREENWALD SARAH STEINBERG
IPC: A61K31/375
Filed: 2009-10-12
Abstract: The present invention provides compositions and methods for preventing or treating diseases and disorders, the composition comprising vitamin C, vitamin E, and at least one of an omega-3 fatty acid and an omega-6 fatty acid.
Patent CA-2777690-A1 (CA)
Title: Mass spectrometry quantitation of p450 protein isoforms in hepatocytes
Inventor: WILLIAMSON BRIAN L
IPC: G01N33/483
Filed: 2010-10-14
Abstract: A method for screening a drug for cytochrome P45O (CYP) induction is provided and can include incubating the drug with a microsome-containing biological sample and then quantitating at least one cytochrome P45G isoform. The isofoms can be selected from 2B6, 3A4, ] A2, and 3A5 isoforms. In some embodiments, the method uses liquid chromatography tandem mass spectrometry (LC-MSMS). A quantitated value can be compared to a threshold value and the drug can be determined to exhibit an acceptable CYP induction potential when the quantitated value does not exceed the threshold value. Isolated peptides are also provided.
Patent CA-2778930-A1 (CA)
Title: Compression molding method and reinforced thermoplastic parts molded thereby
Inventor: GIDEON DAVID E
IPC: B29C70/86
Filed: 2010-09-07
Abstract: A fiber reinforced part is formed from a compression molded thermoplastic resin reinforced with individual fibers of differing lengths randomly oriented substantially throughout the part.
Patent CA-2780222-A1 (CA)
Inventor: UMANSKY SAMUIL
IPC: C12Q1/68
Filed: 2010-11-04
Abstract: Described are methods for detection of neuronal pathologies using quantitative analysis in bodily fluids of synapse and/or neurite small RNAs and application of these methods to early diagnosis and monitoring of neurodegenerative diseases and other neurological disorders.
Patent CA-2781351-A1 (CA)
Inventor: MASON ROBERT T JR
IPC: H04W4/12
Filed: 2012-06-22
Abstract: A wireless mesh network, method, and processor-readable storage medium for operating a network that has a control node that communicates with a plurality of communication nodes, at least one of which comprises a battery-powered communication node, are disclosed. The battery-powered communication node is associated with an electric meter and is configured to maintain time- and frequency synchronization with an electric meter or with the network, to transmit a message, and to listen for a response to the message during a polling period after the message is transmitted.
Patent CA-2781407-A1 (CA)
Inventor: BRENZEL MICHAEL P
IPC: A61B17/56
Filed: 2009-01-14
Abstract: Apparatus and methods for bone fracture repair. The apparatus may include a structural support for positioning a first bone segment relative to a second bone segment. The apparatus may include an anchoring substrate. The anchoring substrate may be configured to compress the first bone segment to the second bone segment. The anchoring substrate may transmit tension from a distal bone segment anchor in the first bone segment to a proximal bone segment anchor in the second bone segment. The apparatus may be configured to be deployed percutaneously in an inner cavity of a bone. The apparatus may be installed in an open fracture. The apparatus may be expanded, self -expanding or configured for mechanically actuation. Some embodiments of the apparatus may include a central axis member that may be used in conjunction with expansion of one or both of the structural support and the anchoring substrate to configure the apparatus.
Patent CA-2782300-A1 (CA)
Inventor: UGA YUSAKU
IPC: A23L7/10
Filed: 2010-12-24
Abstract: Disclosed are a gene which controls the deep-rooted characteristics of a plant, a transgenic plant having said gene transferred thereinto, a method for controlling the deep-rooted characteristics of a plant with the use of said gene, etc. A genetic locus (Dro1 genetic locus) capable of controlling the deep-rooted characteristics of a plant, which was detected between a shallow-rooted rice cultivar IR64 and a deep-rooted rice cultivar Kinandang Patong in a large-scaled segregation population, was examined by high-accurate linkage analysis. As a result, it was clarified that the gene region of Dro1 resides in a 6.0 kbp region located between Dro1-INDEL09, which is an InDel marker, and Dro1-CAPS05, which is a CAPS marker. It was also confirmed that a transgenic plant transformed by the Kinandang Patong type Dro1 gene shows deep-rooted characteristics at a significantly high ratio. It was also confirmed that an individual having the Kinandang Patong type Dro1 gene is resistant to drought.
Patent CA-2784276-A1 (CA)
Inventor: KITO KAZUAKI
IPC: G21C9/012
Filed: 2012-07-05
Abstract: A nuclear power plant has a reactor pressure vessel, a primary containment vessel and a passive pressure suppression pool cooling system. The reactor pressure vessel is installed in the primary containment vessel. A  pressure suppression pool filled with cooling water is formed in a lower portion of the primary containment vessel.  The passive pressure suppression pool cooling system is provided with a steam condensing pool in which cooling water is filled, disposed outside the primary containment vessel, a steam condenser disposed in the steam condensing pool, a steam supply pipe connecting the reactor pressure vessel to the steam condenser, and a condensed water discharge pipe connected to the steam condenser for discharging condensed water generated in the steam condenser. Another end portion of the condensed water discharge pipe is disposed in the pressure suppression pool.
Patent CA-2785469-A1 (CA)
Title: Secreted protein acidic and rich in cysteine (sparc) protein srm/mrm assay
Inventor: KRIZMAN DAVID B
IPC: A61K38/08
Filed: 2010-12-22
Abstract: The current disclosure provides for specific peptides, and derived ionization characteristics of the peptides, from the Secreted Protein Acidic and Rich in Cysteine (SPARC) protein that are particularly advantageous for quantifying the SPARC protein directly in biological samples that have been fixed in formalin by the method of Selected Reaction Monitoring (SRM) mass spectrometry, or what can also be termed as Multiple Reaction Monitoring (MRM) mass spectrometry. Such biological samples are chemically preserved and fixed wherein said biological sample is selected from tissues and cells treated with formaldehyde containing agents/fixatives including formalin-fixed tissue/cells, formalin-f?xed/paraffin embedded (FFPE) tissue/cells, FFPE tissue blocks and cells from those blocks, and tissue culture cells that have been formalin fixed and or paraffin embedded. A protein sample is prepared from said biological sample using the Liquid TissueTM reagents and protocol and the SPARC protein is quantitated in the Liquid TissueTM sample by the method of SRM/MRM mass spectrometry by quantitating in the protein sample at least one or more of the peptides described. These peptides can be quantitated if they reside in a modified or an unmodified form. An example of a modified form of an SPARC peptide is phosphorylation of a tyrosine, threonine, serine, and/or other amino acid residues within the peptide sequence.
Patent CA-2787950-A1 (CA)
Inventor: ICENHOUR CRYSTAL R
IPC: C12S3/20
Filed: 2011-02-16
Abstract: The present disclosure describes an adsorbent and exemplary protocols for extracting nucleic acids, such as DNA and RNA, from complex matrices, such as stool samples and water samples. The adsorbent is activated charcoal coated with a material such as polyvinylpyrrolidone, dextran, or coconut flours. The adsorbent may be used in microcentrifuge spin columns, where it may be present as a slurry in a storage solution. The sample may be prepared by vortexing in a buffer solution, centrifuging, adding a protease to the supernatant, and passing the supernatant through a microcentrifuge spin column containing coated activated charcoal. The key components, including buffer, protease, and spin columns, may be packaged in a kit.
Patent CA-2790502-A1 (CA)
Title: Markers for obesity and methods of use thereof
Inventor: GRANT STRUAN
IPC: C12Q1/68
Filed: 2011-02-22
Abstract: Markers for obesity, particularly childhood obesity, are provided along with methods of use.
Patent CA-2792977-A1 (CA)
Title: Web-based method of personnel management
Inventor: HIXSON AMY
IPC: G06Q10/10
Filed: 2011-03-11
Abstract: The present disclosure provides an application that can be manipulated by users with varying levels of access to schedule tasks for personnel. The application can be accessed remotely, through a web browser or mobile device. In one embodiment, the application is used by models, and their agents and agencies, to manage their schedules.
Patent CA-2793218-A1 (CA)
Title: Methods of obtaining natural products from comestible fluids and methods of use
Inventor: RASKIN ILYA
IPC: A23L5/20
Filed: 2011-03-14
Abstract: Described herein is an enriched substance containing a ground edible material comprising one or more concentrated bioactive natural products from plant juice, as well as methods of producing such enriched substances and methods of using such solids to provide beneficial effects to humans or other animals. Enriched foods comprising the enriched substance(s) are also provided. Also provided are non-sorbed natural products such as sugars, fats oils, and carotenoids found in the non-sorbed plant liquor fraction of plant juice.
Patent CA-2794818-A1 (CA)
Inventor: DO TU DIEN
IPC: H04L9/32
Filed: 2012-11-06
Abstract: A token used when a first device authenticates itself to a third device may be associated with a token issue timestamp. Upon receipt of an indication that all previously issued tokens are to be revoked, a second device may store a revocation timestamp. Upon receiving, from the second device, a request for establishing conditions for a file transfer, from the first device, and an indication of a token issue timestamp associated with the request, the second device may compare the token issue timestamp to the revocation timestamp. Responsive to determining, based on the comparing, that the token issue timestamp precedes the revocation timestamp, the second device may deny the request.
Patent CA-2796639-A1 (CA)
Title: Display ads for door handles providing multisensory stimuli
Inventor: ENGLISH LARRY
IPC: G09F13/00
Filed: 2012-11-26
Abstract: A display ad system for door handles may include electronics that provide multisensory stimuli. In one embodiment, an end cap includes light and sound triggered by a motion detector. In another embodiment, an end cap includes fan-directed aromas triggered by a motion detector. In a third embodiment, a flexible grid of LED  lights backlights the display ad in any time sequence desired, and may be motion-triggered as well. A door handle embodiment may also provide a note board surface as an alternative to showing display ads.
Patent CA-2796690-A1 (CA)
Inventor: HABIBI-NAINI SASAN
IPC: B05C17/005
Filed: 2011-04-06
Abstract: The invention relates to a cartridge that is capable of standing, comprising at least one receiving chamber (2) extending in the longitudinal direction for a medium to be discharged, a cartridge base (4) and a cartridge wall (3), which delimit the receiving chamber (2), wherein the cartridge (1) is produced by means of a thermoforming method or a blow molding method and is designed to be collapsible in a controlled manner. The invention further relates to a discharge device for at least one cartridge (1) according to the invention, comprising a support cartridge (20) for receiving the at least one cartridge (1), a closure unit (40) on a first axial end, and a discharge plunger (50) on a second axial end of the support cartridge (20) for collapsing the at least one cartridge in a controlled manner.
Patent CA-2798102-A1 (CA)
Inventor: GEITNER MANUEL
IPC: H01R12/71
Filed: 2011-03-30
Abstract: The invention relates to a clamping carrier element for flat assemblies having a housing. The invention is distinguished in that the clamping carrier element (1) is formed on the upper face of the housing in such a way that a plurality of clamping carrier elements (1) can be stacked one above the other by means of a connection technique.
Patent CA-2801094-A1 (CA)
Inventor: MURIAS RONALD G
IPC: H04L29/02
Filed: 2013-01-04
Abstract: A wireless mesh is used to collect data such as from a seismic survey. Data is collected at sensor nodes and transmitted in packets to aggregator nodes, where they are aggregated and transmitted to a central controller or a processing node for processing, in which the data is recorded on a storage device. Packets and aggregate packets may be compressed, encrypted and have wrappers applied, and these steps may be reversed in processing. The central controller distributes packets to multiple processing nodes for processing in parallel.
Patent CA-2801356-A1 (CA)
Inventor: FIELDER LANCE I
IPC: E21B43/12
Filed: 2011-05-27
Abstract: A method of unloading liquid from a reservoir includes deploying a pumping system into a wellbore to a location proximate the reservoir using a cable. The pumping system includes a multi-section motor, an isolation device, and a pump. The method further includes supplying a power signal from the surface to the motor via the cable and sequentially operating each section of the motor to mimic a multi-phase motor, thereby driving the pump and lowering a liquid level in the tubular string to a level proximate the reservoir.