baber/WOPTO huggingface dataset:
Patent CA-2646334-A1 (CA)
Inventor: OLDFIELD ERIC
IPC: A61K31/663
Filed: 2007-03-16
Abstract: The invention provides, inter alia, novel bisphosphonate compounds and methods of making and using. In embodiments, the invention provides compounds and methods in connection with research and therapeutic applications, e.g., for tumor cell growth inhibition, activation of gammadelta T cells, inhibition of farnesyldiphosphate (FPPS) and/or undecaprenyldiphosphate synthase enzymes, bone resorption diseases, cancer, immune disorders, immunotherapy, and infectious diseases. In regards to certain embodiments, a surprising advance has been the recognition that certain structural features can significantly enhance the activity of the compounds. For example, the presence of particular cationic species e.g., phosphonium, sulfonium, and arsonium moieties can contribute to desirable functional activity when positioned near a bisphosphonate moiety. In other embodiments of non-nitrogen containing bisphosphonates, terphenyl and benzyl bisphosphonate compounds and methods are provided. Further variations are also provided.
Patent CA-2646690-A1 (CA)
Inventor: GELIBERT STEPHANE
IPC: F16B37/04
Filed: 2007-03-08
Abstract: The clamping device comprises: a screw member with a bearing head and a shank equipped with a threaded portion, a retainer (10) comprising a base (21) equipped with a through-hole (20) for the passage of the shank of the screw member, and retaining means supported by the base (21) to lie vertically in line with the through-hole (20), and designed to collaborate with the threaded portion in order axially to immobilize the screw member relative to the retainer (10). The retaining means consist of flexible and elastic tabs (22, 23) arranged such that they converge. Their free ends (221, 231) between them determine a gap (d) smaller than the nominal diameter of the threaded portion (15) so that they automatically engage with the threads of the threaded portion (15) when the shank (12) is inserted axially into the through-hole (20). A burr (29) is arranged at the periphery of the through-hole (20) towards the flexible tabs (22, 23) to form an end stop for the free ends (221, 231) when the shank (12) is axially withdrawn.
Patent CA-2646817-A1 (CA)
Inventor: BROWN RANDY J
IPC: E06B3/96
Filed: 2007-03-15
Abstract: A hydrogen fuel element (10, 110, 210) includes a heat-generating pyrotechnic charge (12) which comprises any suitable pyrotechnic material and an ammonia borane encasement (16, 116). The encasement partly (encasement 16) or wholly (encasement 116) encases the pyrotechnic charge (12). An ignition train (14) is powered by electrical leads (28a, 28b) to ignite pyrotechnic charge (12) to heat both the ammonia borane binder it contains and the encasement (16, 116), which itself includes or is made entirely of ammonia borane. Hydrogen is evolved from the heated ammonia borane binder and encasement. The hydrogen fuel element (10, 110) may be encased within a suitable housing (30) which may be made of a carbon open-cell foam.
Patent CA-2650115-A1 (CA)
Title: Dynamic routing of customer telephone contacts in real time
Inventor: GONEN SHLOMO
IPC: H04W4/00
Filed: 2007-07-13
Abstract: A process for dynamic routing of customer contacts to call recipients includes establishing accounts in a call recipient contact system for a plurality of call recipients. The plurality of call recipients are permitted to bid against one another for providing goods and/or services to a customer. A contact list is created and call recipients are ranked from a lowest bidding call recipient to a highest bidding call recipient. The contact is received from a customer and routed to the lowest bidding call recipient on the contact list. The call recipient account receiving the contact and fulfilling the transaction is credited an amount bid by the call recipient.
Patent CA-2650178-A1 (CA)
Title: System for providing actions to reduce a carbon footprint
Inventor: VOLKMAN CURT
IPC: G06Q50/00
Filed: 2009-01-19
Abstract: A system is described for aiding a user in reducing a carbon footprint. The system includes a processor to process inputted energy use information, where the energy use information is specific to the user. The processor determines an outputted emission data in accordance with the inputted energy use information. A screenshot displays the outputted emission data, wherein the emission data includes a custom action for reducing the carbon footprint.
Patent CA-2652065-A1 (CA)
Title: Method of optimizing train operation
Inventor: BECK MARSHALL G
IPC: B60T17/22
Filed: 1998-09-11
Abstract: A method of optimizing train operation includes determining conditions of location, track profile and train forces of the train. Next, a set of preliminary train restraint operating parameters are determined from the determined conditions. Also, at least one of a set of preliminary train optimizable operating parameters to minimize train forces, to maximize fuel efficiency and to minimize time to destination is determined. The determined set of preliminary train operating parameters are weighted and combined. Optimized train operating parameters are determined from the weighted and combined preliminary train operating parameters. Engineering train and access is also performed.
Patent CA-2652327-A1 (CA)
Title: Paper trimmer assembly
Inventor: FALENDYSZ GREGORY
IPC: B26D7/02
Filed: 2007-05-10
Abstract: A trimmer assembly for cutting a sheet or sheets of material. The trimmer assembly includes a carriage assembly that is removably connected to a base. The carriage assembly comprises a carriage and a saddle, with a blade fitting within the carriage. The carriage assembly is slidably positioned on a rail, the rail being rotatable relative to the base. A the cut-line indicator (23), such as a print guard (21), is positioned between the rail and the base, and has a cut-line indicator edge (41) for defining a cutting path of the blade.
Patent CA-2654487-A1 (CA)
Inventor: MAHDI ABBAS
IPC: E21B43/26
Filed: 2009-02-17
Abstract: A method of determining when to stop pumping proppant during hydraulic fracturing in a wellbore is described. By accurately detecting tip screen-out with a bottom hole pressure gauge mounted to a perforating gun, the optimal amount of proppant can be supplied to a fracture while avoiding the risks associated with wellbore screen-out.
Patent CA-2654837-A1 (CA)
Title: Process for the preparation of sterically hindered nitroxyl ethers
Inventor: SCHONING KAI-UWE
IPC: C07D211/94
Filed: 2007-06-25
Abstract: The present invention relates to a novel process for the preparation of specific sterically hindered nitroxyl ethers from their corresponding sterically hindered nitroxyl radicals by reacting it with an aldehyde and a hydroperoxide. This nitroxyl ether formation may be carried out from different starting nitroxyl radicals, which are subsequently further reacted to the desired compounds. The compounds prepared by this process are effective as stabilizers for polymers against harmful effects of light, oxygen and/or heat and as flame-retardants for polymers.
Patent CA-2656067-A1 (CA)
Inventor: LYTTLE C RICHARD
IPC: A61K31/136
Filed: 2007-06-22
Abstract: The present invention is directed toward methods for treating vasomotor symptoms, (e.g., hot flashes and night sweats) in a patient in need thereof comprising administering a SERM as described herein.
Patent CA-2657164-A1 (CA)
Inventor: KAUSHAL SHALESH
IPC: A61K38/00
Filed: 2007-07-27
Abstract: Methods are disclosed for treating ophthalmic conditions related to the production of toxic visual cycle products that accumulate in the eye, and are associated with reactions of the visual cycle during medical procedures that expose the eye to light, most commonly the various forms of ophthalmic surgery. Compounds and compositions useful in the these methods, either alone or in combination with other therapeutic agents, are also described, along with methods of screening for new agents useful in said treatments.
Patent CA-2657620-A1 (CA)
Title: Skin lesion exciser and skin-closure device therefor
Inventor: BERKY CRAIG B
IPC: A61B17/32
Filed: 2007-06-08
Abstract: A device for excising tissue and closing a wound that results from excision of the tissue includes structure defining an aperture into which tissue to be excised is exposed. The device also includes a cutting member for excising the tissue, a closure member for closing the wound, and an actuatable drive member associated with the structure. The drive member is actuatable to move the cutting member relative to the aperture for excising the tissue that is exposed in the aperture and for closing the wound with the closure member.
Patent CA-2658544-A1 (CA)
Inventor: GIANNITSIOS DEMETRIOS
IPC: A61M5/44
Filed: 2006-09-07
Abstract: A device for injecting a high viscosity material into a cannula, comprising a container being non-compliant and having an outlet adapted to communicate with the cannula for transferring the high viscosity material thereto, a pressure applicator in fluid communication with the container, the pressure applicator defining a fluid flow path through which an incompressible fluid is displaceable, and a material-moving member interrupting the fluid flow path and defining an incompressible fluid receiving portion on one side thereof in communication with the fluid flow path and a high viscosity material receiving portion in communication with the outlet of the container on an opposed side. The material-moving member being displaceable by a pressure of the incompressible fluid acting thereagainst to force the high viscosity material out of the high viscosity material receiving portion of the container and into the cannula.
Patent CA-2658654-A1 (CA)
Inventor: TURNER ANDREW JOHN
IPC: A61K38/22
Filed: 2007-07-13
Abstract: The invention provides fusion proteins comprising an exendin-4 fused to a transferrin (Tf) via a polypeptide linker, as well as corresponding nucleic acid molecules, vectors, host cells, and pharmaceutical compositions. The invention also provides the use of the exendin-4/Tf fusion proteins for treatment of Type Il diabetes, obesity, and to reduce body weight.
Patent CA-2662501-A1 (CA)
Title: Methods of predicting distant metastasis of lymph node-negative primary breast cancer using biological pathway gene expression analysis
Inventor: WANG YIXIN
IPC: C40B40/10
Filed: 2007-09-05
Abstract: The present invention provides a method for predicting distant metastasis of lymph node negative primary breast cancer by obtaining breast cancer cells; isolating nucleic acid and/or protein from the cells; and analyzing the nucleic acid and/or protein to determine the presence, expression level or status of a Biomarker selected from the pathways in Table 2.
Patent CA-2663122-A1 (CA)
Inventor: BRONDER JOSEPH BERTRAM
IPC: H04L27/26
Filed: 2000-02-17
Abstract: The system for recovering symbol timing offset and carrier frequency error from an orthogonal frequency division multiplexed (OFDM) signal includes a receiver circuit for receiving an OFDM modulated signal representing a series of OFDM symbols, and providing a received signal to an output thereof. A peak development circuit is included for developing a signal having a plurality of signal peaks representing symbol boundary positions for each received OFDM symbol, where each of the signal peaks is developed responsive to an amplitude and phase correspondence produced between the leading and trailing portions of each of the received OFDM symbols. The system includes a circuit for enhancing the signal peak detectability, which includes a circuit for additively superimposing and then filtering the signal peaks, to produce an enhanced signal peak having an improved signal-to-noise ratio. A circuit for establishing a temporal position indicative of the symbol boundary position from at least one of the enhance signal peaks output from the signal enhancing module is also provided. Further, a circuit for recovering the received OFDM signal carrier frequency error corresponding to the temporal position is included.
Patent CA-2663914-A1 (CA)
Title: Goupille de fixation et rondelle utilisees avec un outil de fixation pour fixer une couche d'isolement a un substrat
Inventor: MCCULLOUGH DAVID
IPC: F16B19/00
Filed: 2007-09-05
Abstract: Une pièce de fixation, destinée à être tirée à partir d'un outil de fixation permettant de fixer un isolement à un substrat, comprend une goupille et une rondelle montée sur la goupille de telle sorte que la rondelle se trouve dans une position décalée par rapport à la tête de la goupille au cours de la pénétration de la goupille à travers l'isolement au moyen d'une force appliquée contre la rondelle, et dans une position davantage adjacente par rapport à la tête de la goupille lorsque la goupille a été entraînée dans le substrat par le tir de l'outil. La connexion entre la rondelle et la tige de la goupille est telle que, lorsque la rondelle se trouve dans une position décalée par rapport à la tête de la goupille, elle supporte une charge d'au moins environ 30 N sans déplacement vers la pointe de la goupille, l'outil pouvant être armé avant d'effectuer un tir au moyen d'une force appliquée contre la rondelle lorsque la pointe est mise en prise avec le substrat.
Patent CA-2664563-A1 (CA)
Inventor: KIMBLE EDWARD L
IPC: C07C27/00
Filed: 2007-09-26
Abstract: The GTL process of the invention comprises: reacting a combustible carbonaceous material in a syngas reactor, preferably an autothermal reformer, under conditions to produce a synthesis gas; contacting the synthesis gas with an F-T catalyst to form liquid products and a tail gas; separating the tail gas from the liquid products; separating CO2 from the light products in the tail gas; recovering the light products as additional products for sale or other use and utilizing at least a portion of the separated CO2 as a feed stream to the syngas reactor.
Patent CA-2665472-A1 (CA)
Title: Knife/firing rod connection for surgical instrument
Inventor: SHAH SACHIN
IPC: A61B17/068
Filed: 2009-05-06
Abstract: A surgical instrument including a frame, an elongate portion, a firing rod and an end effector is disclosed. The elongate portion extends distally from the frame and defines a longitudinal axis. The firing rod is disposed at least partially with the elongate portion and is proximally and distally translatable with respect to the elongate portion. The end effector includes a knife and is disposed at a distal portion of the elongate portion.  Distal movement of the firing rod causes a distal end of the firing rod to link with the knife.  Proximal movement of the firing rod moves the linked knife proximally to a first predetermined position. The knife is unlinked from the firing rod when the firing rod has been translated proximally to a second predetermined position.
Patent CA-2667038-A1 (CA)
Title: Preparation of aggregate jobs for production
Inventor: HESCOCK CHRISTIAN H
IPC: G06F15/00
Filed: 2007-09-20
Abstract: System and method for automated scheduling and creation of gangs of individual jobs for production. Individual jobs and related production parameters and order information are retained electronically in a database of pending jobs awaiting production. Based on production capacity at the production facility and the production parameters of the individual pending jobs in the database, a plurality of gang shells having defined production parameters, but not having specific individual jobs associated therewith, are defined and used for scheduling equipment and personnel at the production facility during a work shift or other desired period of time. The specific individual jobs for a gang are selected from the database relatively shortly prior to the gang's scheduled production time.
Patent CA-2667092-A1 (CA)
Title: Modular wiring system with locking elements
Inventor: LINDENSTRAUS LESLIE
IPC: H02J1/00
Filed: 2007-10-25
Abstract: A modular wiring system comprising a functional unit and a wiring unit. There is also a system for coupling the functional unit to the wiring unit in a rotational manner. This system is formed from at least one locking prong comprising electrically conductive material. When the functional unit is coupled to the wiring unit, the locking prong is both electrically and physically coupled to the functional unit. Alternatively, or in addition, the system for coupling the functional unit to the wiring unit in a rotational manner can include at least one flange coupled to the functional unit and at least one flange coupled to the wiring unit. These flanges operate such that when the functional unit and the wiring unit are coupled together, they are rotated to form a locking connection between the flange on the functional unit and the flange on the wiring unit.
Patent CA-2669130-A1 (CA)
Inventor: SLADOJEVIC ROBERT
IPC: E04G13/06
Filed: 2007-10-31
Abstract: A stairway forming system (10) includes a plurality of stacked, elongate stair riser form carriers (12-20), the carriers (12- 20) being longitudinally displaceable relative to one another. An anchoring unit (24) anchors at least a lowermost riser form carrier (12) in position relative to a substrate (26). A positioning assembly (28) is attached to at least one of the riser form carriers (12-20) and cooperates with the remaining riser form carriers for displacing the carriers (14-20) in unison relative to one other to adopt a staggered operative configuration approximating an angle of the stairway to be formed.
Patent CA-2669873-A1 (CA)
Inventor: ARNOLD WANDA
IPC: B28C7/04
Filed: 2009-06-19
Abstract: A production system and method for manufacturing individual building blocks or panels of lightweight fiber reinforced concrete, the method consisting of generating raw materials, conveying measured ingredients, mixing ingredients in accordance with a formula of additives, fiber, cement powder, water, and specially coated and sized Expanded Polystyrene (EPS) beads, and conveying the resultant lightweight admixture through distribution into molds on casting elements, is provided. The production line for manufacturing the lightweight fiber reinforced concrete panels has a main conveyance system, material lifts, storage racks, climate controlled curing facility, yard conveyor system, cross-transfer units, return conveyor, wash station, drying station, release agent station, framework manufacturing equipment. The main conveyance system has casting elements which are designed to receive in an operable arrangement frames and molds.  The formwork or frames are determined based on the design specifications shapes and sizes determined by a CAD system or such other input, be it mechanical or manual, to achieve the panel output production.
Patent CA-2670609-A1 (CA)
Inventor: KUROKAWA KOYA
IPC: G01N27/327
Filed: 2007-11-28
Abstract: It is intended to make it easy to recognize the attachment site of a blood sensor in a blood test device to which the blood sensor is attached by insertion. Especially, it is attempted to make the recognition of the attachment site easy and facilitate the insertion of a blood sensor which is to be attached to a blood test device by a person with visual impairment (in particular, a patient suffering from diabetic retinopathy) for the daily measurement of blood glucose level. More specifically speaking, it is intended to provide a blood test device comprising a housing; an electrical circuit unit contained in the housing; and an attachment site for inserting a blood sensor thereinto that is exposed on the surface of the housing; wherein the surface of the attachment site has a color which is lighter than the surface color of the housing and distinguishable by a patient having impairment in the blue cone.
Patent CA-2672737-A1 (CA)
Title: Anti-viral compounds
Inventor: ANDERSON DAVID D
IPC: A01N43/42
Filed: 2007-12-19
Abstract: Compounds effective in inhibiting replication of Hepatitis C virus ( HCV ) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, coformulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.
Patent CA-2673566-A1 (CA)
Title: Preparation and utility of ccr5 inhibitors
Inventor: GANT THOMAS G
IPC: A61K31/46
Filed: 2007-12-19
Abstract: Disclosed herein are substituted 8-azabicyclo[3.2.1]octane-based anti-infective agents of Formula I, processes of preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.
Patent CA-2680110-A1 (CA)
Inventor: MERGEN GOKHAN
IPC: H04L25/03
Filed: 2008-04-30
Abstract: Disclosed are methods and apparatus for predicting a channel quality indicator in a communication system, and in particular a delayed receiver. A disclosed method for determining the predictive channel quality indicator for a delayed receiver includes determining at least one channel quality indicator from a non-delayed receiver. The method also includes determining another channel quality indicator from the delayed receiver, and then calculating the predictive channel quality indicator for the delayed receiver through a function of the channel quality indicators from the non-delayed receiver and the channel quality indicator from the delayed receiver. Corresponding apparatus are also disclosed.
Patent CA-2680641-A1 (CA)
Title: Method for production of porous ceramic material
Inventor: KUWAYAMA TOMOYA
IPC: C04B38/00
Filed: 2008-03-04
Abstract: The present invention provides a method of producing a porous ceramics material, which rapidly leads formation of a tissue, for example, bone tissue and has a practical strength.   A method of producing a porous ceramics material 11, including step (A): a step of preparing a slurry 21 by dispersing a ceramics raw material in a medium, step (B): a step of filling the slurry 21 in a container 31, and inserting the container 31 in a given direction into a cooling medium 41 having a temperature not higher than the freezing point of the slurry 21 such that the slurry freezes unidirectionally from one end side, step (C): a step of drying the frozen slurry 21 to give a green body, and step (D): a step of firing the green body.
Patent CA-2683648-A1 (CA)
Inventor: NADEN MARK C
IPC: A47J17/16
Filed: 2008-04-03
Abstract: A corn removal device including a housing constructed to be held by a user's hand and adapted to be moved along a surface of an ear of corn. The housing defines a cavity and an opening that accesses the cavity. The corn removal device also includes a blade attached to the housing adjacent to the opening. The blade is adapted to remove corn kernels from the surface of the ear of corn and guide the corn kernels through the opening and into the cavity for storage.
Patent CA-2684223-A1 (CA)
Inventor: HADJIGEORGE GEORGE A
IPC: C10G51/00
Filed: 2008-04-10
Abstract: A system comprising a riser reactor comprising a gas oil feedstock and a first catalyst under catalytic cracking conditions to yield a riser reactor product comprising a cracked gas oil product and a first used catalyst; a intermediate reactor comprising at least a portion of the cracked gas oil product and a second catalyst under high severity conditions to yield a cracked intermediate reactor product and a second used catalyst; wherein the intermediate reactor feedstock comprises at least one of a fatty acid and a fatty acid ester.
Patent CA-2685214-A1 (CA)
Inventor: CHENG XIU XIU
IPC: A61K31/00
Filed: 2002-02-08
Abstract: A pharmaceutical composition designed for once daily dosing of bupropion comprising: (A) a sustained release form of bupropion comprising: (i) a core comprising bupropion or a pharmaceutically acceptable salt or stereoisomer thereof, and (ii) a sustained release component, and (B) an immediate release form of bupropion or a pharmaceutically acceptable salt or stereoisomer thereof.