baber/WOPTO huggingface dataset:
Patent WO-2021092162-A1 (WO)
Title: Biosynthesis of para-nitro-l-phenylalanine
Inventor: KUNJAPUR ADITYA
IPC: C12N15/67
Filed: 2020-11-05
Abstract: The present invention provides a recombinant cell for producing  para -nitro- L -phenylalanine (pN-Phe). The recombinant cell comprises heterologous genes encoding heterologous enzymes. The recombinant cell expresses the heterologous enzymes and contains a native metabolite. The native metabolite is converted to the pN-Phe in the recombinant cell. The biosynthesized pN-Phe may be incorporated into a target polypeptide in the recombinant cell without requiring exposure of the recombinant cell to exogenous pN-Phe. A cell culture comprising the recombinant cell is also provided. Further provided is a method of producing pN-Phe by a recombinant cell comprising heterologous genes encoding heterologous enzymes. The method comprises expressing a native metabolite by the recombinant cell, expressing the heterologous enzymes, and converting the native metabolite to the pN-Phe in the recombinant cell. The method may further comprise incorporating the pN-Phe into the target polypeptide in the recombinant cell.
Patent WO-2021101891-A1 (WO)
Inventor: PLATTNER KYLE
IPC: G06F3/00
Filed: 2020-11-17
Abstract: Systems and methods for improving graphical displays of field data are described herein. In an embodiment, a system generates a plurality of data files by performing, for each data file of the plurality of data files: identifying a start condition; in response to identifying the start condition, generating a new data file; recording data of an apparatus moving through an agricultural field in the new data file, the data comprising locations of the apparatus during said recording; identifying a stop condition; and, in response to identifying the stop condition, storing the new data file. The system causes displaying a field map corresponding to the agricultural field through a graphical user interface. When the system receives input through the graphical user interface selecting multiple locations on the field map, the system identifies, for each selected location of the multiple locations, a corresponding data file of the plurality of data files and generates and displays through the graphical user interface, a geographic region comprising locations in the identified corresponding data files, the geographic region being bounded by locations in one or more of the identified corresponding data files. The system may further update the graphical user interface to include a data panel corresponding to the geographic region.
Patent WO-2021102299-A1 (WO)
Inventor: RENSLO ADAM
IPC: C07D207/06
Filed: 2020-11-20
Abstract: Disclosed herein, inter alia, are compounds and methods for inhibiting Caspase 6 and the treatment of diseases. Provided is a method of treating a neurodegenerative disease, the method including administering to a subject in need thereof an effective amount of a compound as disclosed herein. Provided is a method of treating axonal degradation, the method including administering to a subject in need thereof an effective amount of a compound as disclosed herein. Provided is a method of treating neuroinflammation, the method including administering to a subject in need thereof an effective amount of a compound as disclosed herein. Provided is a method of treating liver disease, the method including administering to a subject in need thereof an effective amount of a compound as disclosed herein.
Patent WO-2021138098-A1 (WO)
Title: Video player synchronization for a streaming video system
Inventor: DESHMUKH SHAILESH
IPC: H04N21/44
Filed: 2020-12-20
Abstract: Systems, devices and processes are provided to facilitate the streaming of video content. In general, the systems, devices and processes facilitate the synchronized streaming of video content to a plurality of video player devices. Specifically, the systems, devices and processes provide for the synchronized streaming of video content to a plurality of video player devices while also providing the ability selectively restrict timing adjustments. For example, the timing adjustments in one or more of the video player devices can be selectively prevented from occurring at certain times to comply with content-based or other such restrictions. As one example, the systems, devices and processes can be used to prevent timing adjustments from being made in one or more video player devices during the displaying of commercials and/or certain live content on the video player devices.
Patent WO-2021178036-A1 (WO)
Inventor: KILBURG DENISE
IPC: A61K8/19
Filed: 2020-12-31
Abstract: The present disclosure provides stable Pickering-type emulsions comprising glycerin and oil, as well as methods of manufacturing the same. In some aspects, such emulsions further comprise magnesium stearate and a non-ionic surfactant as co-emulsifiers.
Patent WO-2021042113-A1 (WO)
Title: Degradation of superabsorbent polymer via oxidative degradation
Inventor: SIMONYAN ARSEN
IPC: C08L101/14
Filed: 2020-08-19
Abstract: A method for degrading crosslinked and poly(acrylic acid)-based superabsorbent polymer (SAP) into soluble polyacrylic acid polymers is disclosed. Degradation is achieved with an oxidative water-soluble salt comprising at least one cation and at least one anion.
Patent WO-2021146422-A1 (WO)
Inventor: TERRY JR
IPC: B25B13/00
Filed: 2021-01-14
Abstract: A dual ratcheting tool having multiple ratchet assemblies and handles for rotating adapters, sockets, and other tools is provided. The dual ratcheting tool includes an upper ratchet assembly independently rotationally and mechanically connected to a lower ratchet assembly; a drive member connected to the upper ratchet assembly and the lower ratchet assembly; an upper handle connected to the upper ratchet assembly, the upper handle having an upper directional switch to set a drive direction of the upper ratchet assembly; and a lower handle connected to the lower ratchet assembly, the lower handle having a lower directional switch to set a drive direction of the lower ratchet assembly. The upper and lower handles of the dual ratcheting tool can independently and in combination can drive a socket more quickly and efficiently than ratchets having a single ratchet assembly and handle.
Patent WO-2022154794-A1 (WO)
Inventor: KEDAIRY FAISAL
IPC: E04B1/19
Filed: 2021-01-15
Abstract: Un élément en béton armé comprend une première poutre en treillis présentant un profil triangulaire, et une seconde poutre en treillis présentant un profil triangulaire, la seconde poutre en treillis présentant une taille inférieure à une taille de la première poutre en treillis. La première poutre en treillis comprend au moins une cavité triangulaire. Une section de la seconde poutre en treillis est positionnée à travers la cavité triangulaire de telle sorte que la seconde poutre en treillis est transversale à la première poutre en treillis. Le positionnement de la seconde poutre en treillis à travers la cavité triangulaire de la première poutre en treillis forme une matrice de poutre en treillis qui est conçue pour fournir un support et un renforcement à une matrice en béton dans un axe x, un axe y, un axe z et une ou plusieurs directions et/ou axes supplémentaires. L'élément en béton armé est résistant aux effets de souffle d'explosifs puissants et/ou aux impacts de projectiles à énergie cinétique.
Patent WO-2021155206-A1 (WO)
Title: Fluid collection assemblies including a skirt cross-reference to related applications
Inventor: JOHANNES ASHLEY MARIE
IPC: A61F5/442
Filed: 2021-01-29
Abstract: An example fluid collection assembly includes a fluid collection assembly defining an opening. The fluid collection assembly includes a fluid impermeable barrier defining at least a portion of a chamber and at least one porous material disposed in the chamber. The opening and the chamber of the fluid collection assembly are configured to receive at least a portion of a penis (e.g., at least the urethral opening of the penis). The fluid collection assembly also includes a skirt. The skirt is configured to attach the fluid collection assembly to an individual. To facilitate attachment to the individual, the skirt may exhibit a high flexibility. The high flexibility allows the skirt to be comfortably attached to the skin about the penis even when the size and/or topography of the skin about the penis varies and/or changes due to movement of the individual.
Patent WO-2021194671-A1 (WO)
Title: Systèmes de laçage et leurs procédés de fabrication
Inventor: MURPHY-REINHERTZ NOAH
IPC: A44B13/00
Filed: 2021-02-22
Abstract: La présente invention concerne des systèmes de laçage pour des articles d'habillement pouvant comprendre un premier élément de lacet continu et un second élément de lacet continu, ayant chacun une partie de réception de lacet fixée à l'article d'habillement, directement ou indirectement, et une partie de laçage pouvant venir en prise avec des ouvertures de boucle respectives de la partie de réception de lacet pour fournir un mécanisme de fermeture. Les articles d'habillement peuvent être des articles chaussants et le système de laçage peut être prévu pour fermer une ouverture dans une partie supérieure de l'article chaussant.
Patent WO-2021173511-A1 (WO)
Inventor: SUDDABY LOUBERT S
IPC: A61B17/70
Filed: 2021-02-23
Abstract: A segmented rod assembly for aligning a spine, including a rod, including at least a first segment arranged to be connected to a first vertebra of the spine, the first segment including a first body and at least one tang extending from the first body, and a second segment arranged to be connected to a second vertebra of the spine, the second segment including a second body and at least one channel arranged in the second body, wherein the at least tang is operatively arranged to engage the at least one channel, and at least one tensioning member arranged within the plurality of segments. A method for creating a segmented alignment rod, the method including receiving a request for a segmented alignment rod, receiving at least one image of a deformed spine, generating, a normal spinal curvature, and generating a segmented alignment rod design.
Patent WO-2022182362-A1 (WO)
Inventor: MATTSON HOWARD
IPC: G06F30/17
Filed: 2021-02-26
Abstract: A method of modifying instances of at least one part P comprising at least one entity e in a mechanical component design, is disclosed. A a first part P 1  has a local co-ordinate frame F, and comprises at least one entity e i . A transform T 1  applied to the part P 1  obtains a part instance P 1 T 1  having an instance co-ordinate frame F 1  in a common global space. At least one entity e 1  in the part instance P 1 T 1  is then marked as a positioning entity pe 1  and grouped rigidly with the instance co-ordinate frame F 1 ,. Causing a positioning entity pe 1  to move in the instance co-ordinate frame F 1  causes all positioning entities pe1 in the instance co-ordinate frame F 1  to move rigidly with the instance co-ordinate frame F 1  and any unmarked entities e 1  to move independently of the rigid grouping of positioning entities pe 1 .
Patent WO-2021183557-A1 (WO)
Title: Surfactants for cleaning products
Inventor: ASIRVATHAM EDWARD
IPC: C11D1/46
Filed: 2021-03-09
Abstract: The present disclosure pertains to surfactants for use in the formulation of detergents, foaming agents, emulsifiers, and degreasers. Some aspects of the invention include formulations suitable for cleaning and/or condition fabrics including upholstery. Some formulations are suitable for in home or commercial dry cleaning. Some of the formulations may be suitable for cleaning hard surfaces including plastic surfaces.
Patent WO-2021216728-A1 (WO)
Inventor: KIM YOUNGEUN
IPC: C12Q1/6844
Filed: 2021-04-21
Abstract: The technology described herein is directed to methods, kits, compositions, devices, and systems for detecting a target nucleic acid, such as a viral RNA. In one aspect, described herein are methods of detecting the target nucleic acid. In other aspects, described herein are compositions, kits, devices, and systems suitable to practice the methods described herein to detect the target nucleic acid.
Patent WO-2021217036-A1 (WO)
Title: Chimères de ciblage protéolytique gper
Inventor: SALEM ALIASGER K
IPC: A61K47/55
Filed: 2021-04-23
Abstract: L'invention concerne une molécule comprenant un ligand du récepteur d'œstrogènes couplé à la protéine G (GPER) couplé à un lieur couplé à un ligand d'ubiquitine ligase E3 et des procédés d'utilisation de la molécule. Dans un mode de réalisation, le ligand GPER est un estradiol et le ligand d'ubiquitine ligase E3 est (S,R,S)-AHPC.
Patent WO-2022081206-A1 (WO)
Title: Glacière intelligente
Inventor: Emde Jason
IPC: F25D23/08
Filed: 2021-04-30
Abstract: Glacière intelligente comprenant un corps de glacière et un couvercle de distribution accouplé au revêtement ou au corps de glacière. Le couvercle de distribution est conçu pour fermer une ouverture qui s'étend à travers le corps de glacière et le revêtement dans au moins une cavité du corps de glacière. La glacière intelligente peut maintenir une température de salubrité alimentaire dans la cavité. Le corps de glacière ou le couvercle de distribution comprend un ensemble de distribution comprenant un mécanisme de verrouillage, un actionneur électrique conçu pour empêcher le déverrouillage du mécanisme de verrouillage, et un dispositif informatique. Le dispositif informatique peut déclencher un accès à la cavité du corps de glacière.
Patent WO-2021231948-A1 (WO)
Inventor: HO DAVID
IPC: G01N27/72
Filed: 2021-05-14
Abstract: La présente invention concerne des biocapteurs à base de carbone et des systèmes de biocapteurs. L'invention concerne en outre des procédés de détection rapide d'un matériel cible dans un échantillon biologique à l'aide des biocapteurs et des systèmes de biocapteurs décrits ici pour caractériser un profil d'antigène d'un pathogène et/ou une réponse immunitaire d'un sujet à une exposition à un agent pathogène.
Patent WO-2022265644-A1 (WO)
Title: System and method to generate augmented training data for neural network
Inventor: ZHANG QILIN
IPC: G06N3/02
Filed: 2021-06-17
Abstract: A robotic system capable of being trained with a plurality of images that are synthetically augmented from an initial image data set includes a training system toward that end. An image augmentation system includes in one form a neural network trained to generate synthetic images using a generative adversarial network which includes the ability to synthesize images having various poses with adjustments to image parameters such as light and color among potential others. In another form the image augmentation system includes a set of images projected or transformed from its original pose to a number of different poses using an affine transform, and the ability to progress across an entire dimensional space of anticipated robot movements which produce various potential poses.
Patent WO-2021263083-A1 (WO)
Inventor: PRATER CRAIG
IPC: G01J3/427
Filed: 2021-06-25
Abstract: Improvements in spectroscopy are disclosed herein that rely on the interaction of both an infrared beam and a probe beam with a sample. These beams are used in a pump-probe arrangement, with a fiber optic probe collecting the beams of infrared and probe radiation from the infrared source and delivering it to the sample. At least a portion of the beam of infrared radiation and the beam of probe radiation overlap one another on the sample. The fiber also collects probe radiation that has interacted with the sample. A detector can use this collected signal to indicate an intensity of the collected probe radiation, and an analyzer can generate a signal indicative of infrared absorption of the sample adjacent the fiber.
Patent WO-2022039885-A1 (WO)
Inventor: NALBANT MEHMET K
IPC: H02J50/10
Filed: 2021-07-23
Abstract: L'invention concerne des dispositifs de transfert de puissance sans fil pouvant être configurés pour négocier les uns avec les autres pour fonctionner. Par exemple, une norme de puissance sans fil peut fournir divers niveaux de distribution de puissance, diverses fréquences de transfert de puissance, diverses tensions de fonctionnement, etc. Il peut exister des instances dans lesquelles il est souhaitable de fournir des dispositifs de transfert de puissance sans fil (à la fois PTx et PRx) qui peuvent offrir une performance améliorée lorsqu'ils sont appariés avec un dispositif compatible. Par exemple, des dispositifs peuvent être configurés pour fonctionner à des niveaux de puissance plus élevés ou plus granulaires, à des fréquences différentes, etc.
Patent WO-2022026454-A1 (WO)
Inventor: FANG JUN
IPC: A61K9/51
Filed: 2021-07-27
Abstract: We have discovered a chemical cocktail that selectively induces a robust expansion of myogenic stem cells from readily-obtainable dermal cells and from muscle stromal cells. By differential plating and lineage tracing, we show that Pax7+ cells were the major source for chemical-induced myogenic stem cells (CiMCs). We further performed single-cell RNA sequencing (scRNA-seq) analysis to characterize the transcriptomic profile of CiMCs and demonstrate a specific expansion of myogenic cells from heterogeneous dermal cell population. Upon transplantation into the injured muscle, CiMCs were efficiently engrafted and improved functional muscle regeneration in both adult and aged mice. Furthermore, an  in situ  therapeutic modality using this cocktail was developed by loading the chemical cocktail into injectable nanoparticles, which enabled a sustained release of the cocktail in injured muscle and a local expansion of resident satellite cells for muscle regeneration in adult and aged mice.
Patent WO-2022055636-A1 (WO)
Title: Saw-based hydrogel testing for detecting viruses or other antigens
Inventor: SERINO ANTHONY
IPC: G01N29/02
Filed: 2021-08-03
Abstract: An apparatus includes a surface acoustic wave (SAW) sensor (100). The SAW sensor includes a piezoelectric substrate (102). The SAW sensor also includes first and second interdigitating transistors (104a-104b) over the piezoelectric substrate. The first interdigitating transistor (104a) is configured to convert an input electrical signal into an acoustic wave. The second interdigitating transistor (104b) is configured to convert the acoustic wave into an output electrical signal. The piezoelectric substrate is configured to transport the acoustic wave. The SAW sensor further includes a detection layer (116) over the piezoelectric substrate and positioned at least partially between the first and second interdigitating transistors. The detection layer includes (i) antibodies (302) configured to bind to one or more biological analytes and (ii) a hydrogel layer (306) over the antibodies.
Patent WO-2022040024-A1 (WO)
Title: Wireless anti-static device for esd mitigation
Inventor: STEVENSON DAAN
IPC: B64G1/52
Filed: 2021-08-13
Abstract: A wireless anti-static device is disclosed, including an electronic sensing circuit that measures the polarity and electrostatic potential of the subject relative to its surroundings. Ion guns of positive and negative polarities are able to transfer an arbitrary quantity and polarity of charge from the subject by ejecting ionized air molecules into the surrounding environment. A control unit is programmed to trigger the appropriate ion gun when a corresponding charge is measured on the body, in order to continually maintain the net charge on the body below a desired threshold. The subject is thus effectively grounded relative to its environment without requiring physical tethers to ground.
Patent WO-2022055976-A1 (WO)
Inventor: HUI BING
IPC: H04L5/00
Filed: 2021-09-08
Abstract: A wireless device may determine to trigger a sidelink pre-emption of first resources for a first sidelink transmission, based on: a first priority value of the first sidelink transmission being higher than a first priority threshold, and a second priority value of a second sidelink transmission being lower than a second priority threshold. The wireless device may transmit, in response to the determining, the first sidelink transmission via transmission resources.
Patent WO-2022056240-A1 (WO)
Inventor: LU LIN
IPC: H04W52/28
Filed: 2021-09-10
Abstract: Techniques and apparatus for configurable radio frequency (RF) exposure compliance based on region. An example method of wireless communication by a user equipment (UE) generally includes identifying a region in which the UE is located, selecting at least one of a mode or one or more parameters for RF exposure compliance based on the identified region, and transmitting a signal at a transmission power level based at least in part on the at least one of the selected mode or the selected one or more parameters.
Patent WO-2022066523-A1 (WO)
Inventor: LYNCH RYAN DESMOND
IPC: A61B1/00
Filed: 2021-09-17
Abstract: The present disclosure relates generally to systems and methods for performing endoscopic procedures, and, more particularly, to location and access devices, systems, and methods for gastrojejunostomy procedures. In an aspect a medical device locator (202) may include an elongate member (204) having a proximal end, a distal end, a longitudinal axis, and a length extending along the longitudinal axis. An inflatable member (200) may be disposed about the distal end of the elongate member. The inflatable member may have a first inflated volume and a second inflated volume larger than the first inflated volume. The elongate member may include a fluid lumen extending therealong. The fluid lumen may be in fluid communication with the inflatable member and may be configured to pulsate the inflatable member between the first inflated volume and the second inflated volume.
Patent WO-2022072620-A1 (WO)
Title: Methods of treating fibromyalgia with neuroactive steroids
Inventor: LEVIN ANDREW
IPC: A01N51/00
Filed: 2021-09-30
Abstract: The invention relates to methods of treating fibromyalgia in a human subject by providing the steroid of Formula (I):
Patent WO-2022086769-A1 (WO)
Inventor: UONG DO D
IPC: A61F2/24
Filed: 2021-10-13
Abstract: La présente divulgation concerne un dispositif d'annuloplastie conçu pour être implanté par l'intermédiaire d'un cathéter, un dispositif de serrage appliqué en annuloplastie, et un procédé de réalisation d'annuloplastie. Le dispositif d'annuloplastie comprend un anneau de mise en forme et un élément d'ancrage au tissu. L'anneau de mise en forme comprend un premier élément barre, un deuxième élément barre et un troisième élément barre qui sont reliés par l'intermédiaire d'un élément extensible et compressible. Le premier élément barre, le deuxième élément barre et le troisième élément barre comportent chacun une partie de liaison permettant l'ancrage de l'anneau de mise en forme au tissu physiologique par l'élément d'ancrage au tissu. Un fil de réglage est disposé dans une cavité interne de l'élément extensible et compressible, pour régler la taille de l'anneau de mise en forme, permettant ainsi de régler la taille de l'annulus physiologique.