baber/WOPTO huggingface dataset:
Patent PT-695169-E (PT)
Inventor: KIM SINIL
IPC: A61K9/133
Filed: 1994-04-22
Abstract: PCT No. PCT/US94/04490 Sec. 371 Date Dec. 21, 1995 Sec. 102(e) Date Dec. 21, 1995 PCT Filed Apr. 22, 1994 PCT Pub. No. WO94/23697 PCT Pub. Date Oct. 27, 1994Liposomes containing cyclodextrin in the encapsulated aqueous phase are useful for encapsulation of biologically active substances, especially those which are hydrophilic. The encapsulated cyclodextrin facilitates a slow, controlled release of pharmacologic compounds from the liposomes. The novel methods of the present invention allow the treatment of a variety of pathophysiological states by administering the cyclodextrin-containing liposomes encapsulating the pharmacologic compounds. The present invention also provides a novel method of extending the half life of a pharmacologic compound in an animal.
Patent PT-718349-E (PT)
Inventor: NABER BERNHARD
IPC: C08J11/24
Filed: 1995-12-15
Abstract: The prodn. of recycled polyols (I) from rigid polyurethane (PU) foam comprises glycolysis of the foam with short-chain cpds. contg. PH gps. (II), followed by the addn. of epoxidised natural oil(s) (III) to the reaction mixt. at a temp. which is 10-80 deg. C. below the glycolysis temp. Also claimed is recycled polyol obtd. by this process.
Patent PT-696480-E (PT)
Inventor: BOUGAMONT JEAN-LOUIS
IPC: B05B11/00
Filed: 1995-08-09
Abstract: The pump has a body (1) with a inlet (11) discharging into a measuring chamber (12). The measuring chamber has an inlet valve (20) and a piston (3) with a plunger (30) which has an axial jet (31). The jet enlarges in its lower part into a corolla (32) receiving a flexible membrane lining (4). The jet internal channel (31a) leads to an outlet valve (40). The outlet valve is part of a single deformable piece forming the membrane constituted from a lower U collar (42), assembled on the corolla of the plunger. At the top is fastened an external cylindrical sealing skirt (43) and the piston back, in its rest position, extends an annular flange (44) at the membrane junction on the body. At the upper narrow end of the conical outlet valve a cut-out (4) in the membrane is edged by a lip opening onto the outlet orifice.
Patent PT-734381-E (PT)
Inventor: DORN CONRAD P
IPC: C07D413/14
Filed: 1994-12-13
Abstract: Substituted heterocycles of general structural formula (I) or a pharmaceutically acceptable salt thereof, wherein: R<1> is selected from the group consisting of: hydrogen; C1-6 alkyl, unsubstituted or substituted; C2-6 alkenyl, unsubstituted or substituted; C2-6 alkynyl; phenyl, unsubstitued or substituted; X is selected from the group consisting of: -O-, -S-, -SO-, -SO2-; Y is selected from the group consisting of: a single bond, -O-, -S-, -CO-, -CH2, -CHR5- and -CR<15>R<16>; Z = C1-6 alkyl, are tachykinin receptor antagonists useful in the treatment of inflammatory diseases, pain or migraine, asthma and emesis, and calcium channel blockers useful in the treatment of cardiovascular conditions such as angina, hypertension or ischemia.
Patent PT-781341-E (PT)
Title: Method for the production of recombinant proteins, plasmids and modified cells
Inventor: CROUZET JOEL
IPC: C07K14/50
Filed: 1995-09-14
Abstract: PCT No. PCT/FR95/01178 Sec. 371 Date Mar. 12, 1997 Sec. 102(e) Date Mar. 12, 1997 PCT Filed Sep. 14, 1995 PCT Pub. No. WO96/08572 PCT Pub. Date Mar. 21, 1996Expression plasmids comprising a nucleic acid sequence of interest controlled by a T7 bacteriophage promoter and a stabilizing region comprising all or part of the par region of the RP4 plasmid or a derivative thereof. The invention also concerns the use of said plasmids in the production of recombinant products.
Patent PT-847390-E (PT)
Inventor: MILANESE ALBERTO
IPC: C07D223/22
Filed: 1996-01-03
Abstract: PCT No. PCT/EP96/00004 Sec. 371 Date Dec. 24, 1996 Sec. 102(e) Date Dec. 24, 1996 PCT Filed Jan. 3, 1996 PCT Pub. No. WO96/21649 PCT Pub. Date Jul. 18, 1996A novel process for the preparation of 10-0x0-10,11-dihydro-5H-dibenz(b,f)azepin-5-carboxamide (VI) consists of starting group 10-methoxy-5H-dibenz(b,f)azepine (IV) and subjecting compound (IV) to direct carbamoylation with isocyanic acid generated in situ from cyanates and acids and then subjecting the product to acid hydrolysis of the enol ether. An alternative process to obtain (VI) starts (IV) effecting the hydrolysis reaction before the carbamoylation. In this case the carbamoylating agent is chlorosulfonyl isocyanate.
Patent PT-859578-E (PT)
Inventor: SUEMER AYKUT
IPC: A61F2/46
Filed: 1996-11-08
Abstract: PCT No. PCT/CH96/00395 Sec. 371 Date Jul. 6, 1998 Sec. 102(e) Date Jul. 6, 1998 PCT Filed Nov. 8, 1996 PCT Pub. No. WO97/17040 PCT Pub. Date May 15, 1997An artificial cotyloid socket having a domal outer shell (1) and a domal inner shell (2) subtending between them a cavity (3). Each of the outer and inner shells (1, 2) having a domal wall that merges into a rim (5, 6). The outer and inner shells are undetachably joined to each other at their rims (5, 6). The rim of the outer shell is reinforced and disposed relatively beneath a circle of merging (7). The circle of merging is defined by the intersection of the outer shell domal wall and the outer shell rim. A thickness of the wall continuously increases as one moves from a pole (4) of the outer shell toward the circle of merging (7).
Patent PT-810137-E (PT)
Inventor: RODET ALAIN
IPC: B61C9/38
Filed: 1997-05-15
Abstract: The shell (Cv) of the vehicle bears upon the cross-beam (Tc) through a ball-bearing ring (Cr). The cross-beam is coupled by secondary suspension (Su) to the lateral casings (Pr1,Pr2) of the beam of a reduction bridge implemented in three parts. This bridge combines the functions of a load-carrier, an axle drive and a transmission for the torque from the traction motor(s), whose axes are parallel to the axle. The motor(s) may be flanged to the beam of the bridge or may float with respect to it.
Patent PT-928182-E (PT)
Inventor: REYNOLDS DAVID L
IPC: A61J3/00
Filed: 1997-01-10
Abstract: A system is provided for providing syringes filled with pharmaceuticals whose components must be stored separately, using an active ingredient in a pharmaceutical vial, a diluent in a protosyringe such as a bottomless vial or a cartridge, and a combiner assembly which enables the content of the pharmaceutical vial to be transferred into the protosyringe and converts it into a ready-to-use syringe on activation. The combined assembly included a tubular body having recesses at opposite ends for receiving capped ends of the vial and the protosyringe, and a hub and needle assembly between penetrable sheaths or shields which acts on activation of the assembly to enable the transfer and conversion referred to above. Components of the system may also be used to convert protosyringes and pharmaceutical vials containing pharmaceuticals into delivery systems.
Patent PT-912103-E (PT)
Inventor: BRUCE GRAHAM
IPC: A23C19/068
Filed: 1997-07-21
Abstract: PCT No. PCT/GB97/01957 Sec. 371 Date May 6, 1999 Sec. 102(e) Date May 6, 1999 PCT Filed Jul. 21, 1997 PCT Pub. No. WO98/03073 PCT Pub. Date Jan. 29, 1998Pasta filata cheeses, such as mozzarella, are made in the conventional way, except that the conventional step of heating and stretching is replaced by treatment with a proteolytic enzyme, thereby providing for significant economies in manufacture. Brine treatment may also be replaced by dry salting in this method.
Patent PT-957914-E (PT)
Inventor: PLACHETKA JOHN R
IPC: A61K31/495
Filed: 1997-08-15
Abstract: This invention comprises a method of treating migraine in a human comprising co-timely administering of a therapeutically effective amount of a 5-HT agonist coordinated with a therapeutically effective amount of an analgesic, particularly a long-acting NSAID, and in some instances, doses below those ordinarily considered as minimum effective doses as to one or both 5-HT agonist and long-acting NSAID. Dosage forms are also included herein.
Patent PT-882823-E (PT)
Inventor: RUPFLIN FRITZ
IPC: D03D49/06
Filed: 1998-04-22
Abstract: The coupling has flanges with tooth structures to be engaged and disengaged with each other for drive transmission The coupling system for a warp beam for the rotary drive at a loom has coupling flanges (2,8) each with toothed structures (3,9) at the end sides. Setting units (19) are at the mounting cap (12) to engage and disengage the tooth structure (9) of the coupling flange (8) at the mounting cap and the tooth structure (3) of the coupling flange (2) at the warp beam tube (1). The mounting cap (12) additionally has clamps (6,17) to lock the flanges (2,8) together when they are engaged.
Patent PT-889056-E (PT)
IPC: C08B37/16
Filed: 1998-06-17
Abstract: Sulfoalkyl ether cyclodextrins are produced by a process of treating an unsubstituted cyclodextrin starting material with an alkyl sultone in the presence of a base. The base is added in a stepwise, pH controlled manner so that substantially the entire initial charge of cyclodextrin starting material is at least partially reacted. Additional base is then added to complete the reaction, and residual alkyl sultone is destroyed. The product advantageously contains low levels of both residual cyclodextrin and residual alkyl sultone.
Patent PT-958289-E (PT)
Inventor: MEERPOEL LIEVEN
IPC: A61K/
Filed: 1998-02-03
Abstract: The present invention concerns novel compounds of formulathe N-oxide forms, the pharmaceutically acceptable addition salts thereof and stereochemically isomeric forms thereof, wherein -A-B- forms a bivalent radical of formula -N=CH- (a), -CH=N- (b), -CH=CH- (c), L represents the acyl moiety of an amino acid; D is an azole containing 1,3- or 1,4-dioxolane derivative as broad-spectrum antifungals; their preparation, compositions containing them and their use as a medicine.
Patent PT-1029233-E (PT)
Inventor: VOJNOVIC BORIVOJ
IPC: G01N21/78
Filed: 1998-06-19
Abstract: A system for measuring the concentration of an assay substance comprising a sensor having an optical fiber (10) on one end of which is coated a body (22). A fluorophor is dispersed within the body (22), the fluorescent activity of which is altered in relationship to the concentration of the assay substance. Light from a source such as an LED (40) is carried by the fiber (10) to the body (22). Light emitted by the fluorophor is carried to a detector unit (54) along the fiber (10). Concentration of the assay substance is determined by measurement of the characteristics of the growth in emitted light following activation of the LED (40).
Patent PT-1027091-E (PT)
Inventor: WATRELOT ANTOINE
IPC: A61M25/00
Filed: 1998-10-05
Abstract: Multipurpose catheter including a small diameter cylindrical body including a first end, a second end, and at least three internal non-coaxial channels. A connection mechanism is disposed adjacent the first end for communicating with the non-coaxial channels. The connection mechanism comprises an ergonomic monobloc head which is sealingly attached to the first end of the cylindrical body. The monobloc head comprises a bulged wall having at least three independent inlets for communicating with the three non-coaxial channels via bores and two walls which continue from the bulged wall. An inwardly curved connecting wall is also included. The connecting wall is disposed adjacent the first end of the cylindrical body and connects the two walls. The two walls comprise first opposite facing inclined surfaces and second opposite facing inclined surfaces having a different inclination. One of the at least three channels is adapted to provide communication between at least one of the independent inlets and an elastically deformable balloon disposed adjacent the second end. Two of the at least three channels are adapted to allow the introduction of one of a liquid and a surgical mandrin. The ergonomic monobloc head is adapted to be gripped by a user.
Patent PT-1037819-E (PT)
Inventor: FRESNEL ERIC
IPC: B65D75/00
Filed: 1998-12-08
Abstract: The invention relates to a device for supporting at least one object that is to be suspended from a peg of a display unit. According to the invention, it consists in a sleeve (10) of heat-shrink plastics material having a non-shrunk top portion (10.1) which is flattened face against face and has a through hole (11) for suspending the device, and a bottom portion (10.2) which is shrunk on a top portion of the object(s) concerned so as to enable said object(s) to be suspended.
Patent PT-1098693-E (PT)
Inventor: LISTNER UWE
IPC: B01D47/10
Filed: 1999-07-05
Abstract: Method and apparatus for wet-cleaning crude gas streams, the method involving a flow of the crude gas stream without a pressure drop or with a low pressure drop up to 30 mbar, preferably up to 20 mbar, flowing through one or more parallel venturi throats which is/are sprayed with a scrubbing liquid via one or more periodically pulsating hybrid nozzles.
Patent SG-22785-G (SG)
Title: Hinges,and panel assemblies incorporating such hinges
IPC: E05D1/00
Filed: 1985-03-26
Abstract: A hinge structure comprising first and second hinge bodies adapted for securement thereto of respective members desired to be hingedly connected to one another, the bodies presenting, to each other, confronting faces having parallel first and second hinge edges with corresponding the edges aligned with one another, connecting means in the form of a first web or strap hingedly connecting the first hinge edge of the first hinge body to the second hinge edge of the second hinge body, and a second web or strap hingedly connecting the second hinge edge of the first hinge body to the first hinge edge of the second body, whereby the bodies may be pivoted relative to one another as desired about the one or the other of two alternative pivot axes corresponding approximately to the first and second hinge edges, the first and second webs or straps each corresponding in extent to about one half of the confronting faces of the hinge bodies. The hinge structure advantageously provides a connection between adjacent member such as panels desired to be hingedly connected and permits the panels to swing to either side of the plane of the other panel in a simple, convenient and economic manner as compared with prior art hinge structures.
Patent SG-27295-G (SG)
Title: Frequency limited resonant regulator
Inventor: TRUSKALO WALTER
IPC: H02M3/337
Filed: 1995-02-17
Abstract: In a resonant regulator power supply, a resonant circuit (10) is coupled to a source (S1,S2) of alternating input voltage that is controllable in operating frequency. A power transformer primary winding (W1) is coupled across the capacitive element (CO) of the resonant circuit (10) for generating an output voltage across a secondary winding (W3). A control circuit (50) varies the operating frequency in a negative feedback loop to regulate the output voltage on the positive slope of the frequency characteristic curve. A frequency limiting circuit (60) prevents the operating frequency from passing through the resonance frequency of the resonant circuit. <IMAGE>
Patent SG-32889-G (SG)
Title: Multiple strand elastic means
IPC: C09J5/00
Filed: 1989-05-22
Abstract: An elastic means is provided for a disposable diaper which elastic means has substantially parallel multiple strands of stretched elastic adhered between two layers of fabric by at least one sinusoidal adhesive line.
Patent IE-43842-L (IE)
Title: Food product
IPC: A23L19/18
Filed: 1976-02-05
Abstract: A semi-manufactured product, which can be converted into a food product by boiling, baking or frying, is produced by a) extruding a dough, which has been formed by mixing a dough mixture of one or more edible starches or starch-containing materials together with less than 3.5%, based on the dry weight of the dough mixture, of a non-toxic ionic salt with water, the overall starch content of the dough and the amount of free gelatinised starch being chosen so that a partially gelatinised product having a semi-translucent appearance is formed after extrusion; b) cutting the extruded product immediately or shortly after extrusion into pieces of predetermined shape or property; and c) drying the pieces at a temperature of up to 60 DEG C to a moisture content of 9 to 13% to form a semi-manufactured product. The semi-manufactured product obtained is used in particular for the production of cereal-based snack products.
[GB1525631A]
Patent IE-850359-L (IE)
Title: Liposome-gel-composition
IPC: A61K9/127
Filed: 1985-02-14
Abstract: Compositions and methods for maintaining reservoirs of bioactive agents by sequestering the reservoir in a gel matrix are described. In particular, liposomes containing an entrapped bioactive agent are sequestered in a gel matrix. The resulting liposome-gel compositions may be used in vivo or in vitro to provide for sustained release of the bioactive agent. The gel matrix inhibits the dispersion and clearance of the sequestered liposomes without interfering with the ability of the liposomes to release the entrapped bioactive agent. Furthermore, the rate of release of the bioactive agent from the liposome-gel compositions may be varied by altering the composition of the liposomes and/or gels.
[US4708861A]
Patent IE-35061-L (IE)
Title: Dinitrophenyl disulphides
Filed: 1971-04-15
Abstract: Bis(hydroxy, amino, or substituted lower alkyl, alkenyl, or alkynylamino-3,5-dinitrophenyl)disulfide prepared by treating 4-chloro-3,5-dinitrophenyl thiocyanate with an alkali metal hydroxide, carbonate, acid carbonate, or nitrite, ammonium hydroxide, ammonia, or a primary or secondary lower aliphatic amine; useful as intermediates for the synthesis of herbicides.
[US3725479A]
Patent IE-41522-L (IE)
Title: Dispensing instrument.
IPC: A61F6/22
Filed: 1974-03-08
Abstract: 1470571 Catheters; syringes POPULATION RESEARCH INC 8 March 1974 [9 March 1973 31 Jan 1974] 10593/74 Heading A5R A uterine catheter tube 441 has an expandable member 443 at or near the dental end, the expandable member being made of soft, relaxed, flexible, elastic material having a low modulus of elasticity e.g. rubber, and being of sufficient size relative to the dimensions of the catheter tube to expand longitudinally of the catheter tube at least as far as one end thereof, whereby the expandable member can be expanded to substantially fill the uterine cavity and conform to the shape thereof. The instrument comprises a tube 441 insertable into the uterus and through which a balloon 443 on the innermost end may be inflated via apertures 448 from a container 459 by actuating a piston 463. One or more tubes 453 extend through the tube 441 to an outlet passage 452 in a head 417 at the innermost end of the tube 441 and convey medicaments from one or more containers 474 to the outlet passage 452 on operating a piston or pistons 477. The pistons 463, 477 controlling the inflation of the balloon and the dispensing of the medicaments are operated under the control of a single actuator 468 or a pistol grip trigger (320) Figure 27 (not shown) so that the balloon is first partially inflated, the medicament is then dispensed and, finally, the balloon is inflated sufficiently to fill the uterus and thus drive the medicament into the Fallopian tubes. The actuator 468 is initially connected to the plungers 486, 514 of the pistons 463, 477, respectively, by links 501, 518. On first projecting the actuator 468 the plungers 486, 514 are moved to displace the piston 463 and partially inflate the balloon and to project the medicament container 479 so that its forward end is pierced by a needle 472 which communicates with the dispensing tube 471. On continued movement of the actuator, the link 501 is moved away from the actuator but the plunger 514 continues to be displaced to cause discharge of medicament via the tube 471. The link 518 is then. disconnected from the actuator and the first link 501 reconnected so that projection of the plunger 486 recommences and inflation of the balloon is completed. The inflation fluid may be atmospheric air which enters the container 459 through a hole 466. Two medicament containers may be discharged simultaneously using a bifurcated plunger (514A) Figure 37 (not shown). The head (651) may include a chamber in which the contents of the two containers are mixed before discharge. The medicament and inflation fluid containers (44, 51, 53) Figure 1 (not shown) may be separate and independently operable, each container, Figures 4 to 19, (not shown) comprising a sealed cylinder or collapsible container from which the contents are ejected by a manually operable piston which also causes a needle to pierce a wall of the container. The containers may be contained in the same or separate housings. The balloon may be fully expanded to fill the uterus before the fluid is dispensed into the uterus.
[GB1470571A]
Patent IE-34109-L (IE)
Title: Calcium nitrate blasting slurry compositions
IPC: C06B47/14
Filed: 1970-04-21
Abstract: Slurry blasting compositions of low water content and high density, including substantial proportions of calcium nitrate as an oxidizer component, can be sensitized in various ways to produce economical explosive compositions. Sensitizers may include aluminum powder, granular explosives such as smokeless powder, TNT, etc.; a particularly preferred sensitizer or fuel is ethylene glycol. Solid carbonaceous fuels and conventional thickeners may be added. The calcium nitrate may be produced directly from burned lime with nitric acid and/or other nitrates.
[US3660181A]
Patent IE-850808-L (IE)
Title: Wire dispensing device
IPC: B65H75/34
Filed: 1985-03-29
Abstract: An apparatus for the spooling storage and dispensing of reels of wire in which there is provided means for measuring the pulling force on the wire so that the speed of rotation of the reel is in proportion to this pulling force. In one embodiment this comprises three pulleys (21, 22, 23), two fixed (21, 22) and the third (23) movable towards and away from an in-line position between the pulleys under the influence of the tension imparted to the wire. The movable pulley is connected to a potentiometer (36) which controls the speed of an electric motor used to drive the reel.
Patent IE-820851-L (IE)
Title: Indole derivatives
IPC: C07D209/08
Filed: 1982-04-08
Abstract: Indole derivatives of Formula I <IMAGE> (I) wherein R1 is hydrogen, alkyl of 1-6 carbon atoms, or benzyl R2 is hydrogen, alkyl of up to 4 carbon atoms, free or esterified hydroxyalkyl of up to 4 carbon atoms, or free, amidated or esterified carboxy or carboxyalkyl, R3 is hydrogen or alkyl containing 1-6 carbon atoms, R4 is hydrogen or alkyl containing 1-6 carbon atoms and R5 is hydrogen, or alkyl, alkenyl, or cycloalkyl, all of which per se contain up to 6 carbon atoms, and all of which are optionally substituted by a free or esterified carboxy group or by an optionally substituted phenyl group; or a polymethylene group of up to 8 carbon atoms linking the first indole residue to a second indole residue of Formula Ia <IMAGE> (Ia) wherein R1, R2, R3, and R4 are as defined above, and the physiologically acceptable salts thereof with acids and, optionally, their alkali metal and alkaline earth metal salts, possess valuable pharmacological properties, such as stimulating beta -receptors and prevention of premature labor, are described.
[US4835175A]
Patent FI-820763-L (FI)
Inventor: HOUGAARD TAGE
IPC: F24F13/15
Filed: 1982-03-04
Abstract: In a ventilation damper assembly in which a number of wing-shaped rectangular damper blades (7) are rotatably positioned with parallel axes of rotation between opposite frame members (1) in a rectangular damper frame, lateral tightening at the frame members is obtained without using particular tightening means, by forming each frame member (1) with a substantially convex cross-sectional shape with the minimum distance between the frame members aligned with the bearings (13) for the journals (12) of the damper blades (7), while each damper blade (7) comprises end portions (11) with a curved edge portion (11a) facing the frame members (1).