baber/WOPTO huggingface dataset:
Patent ES-2250617-T3 (ES)
Inventor: RAPIN JEAN
IPC: A61K38/06
Filed: 2002-02-05
Granted: 2006-04-16
Abstract: The invention relates to the use of specific tripeptides for the treatment of postlesional diseases of ischemic, traumatic or toxic origin. The tripeptide derivatives satisfy formula (I), wherein X represents OH, (C<SUB>1-5</SUB>)alkoxy, NH<SUB>2</SUB>, NH-C<SUB>1-5</SUB>-alkyl, N(C<SUB>1-5 </SUB>alkyl)<SUB>2</SUB>; R<SUB>1 </SUB>is a residue derived from any of the amino acids Phe, Tyr, Trp, Pro, each of which may optionally be substituted by a (C<SUB>1-5</SUB>) alkoxy group, a (C<SUB>1-5</SUB>) alkyl group or a halogen atom, and Ala, Val, Leu, or Ile; R<SUB>2 </SUB>is a residue which is derived from any of the amino acids Gly, Ala, Ile, Val, Ser, Thr, His, Arg, Lys, Pro, Glu, Gln, pGlu, Asp, Leu and Asn; R<SUB>3 </SUB>and R<SUB>4 </SUB>independently represent H, OH, (C1 -C5) alkyl, or (C<SUB>1-5</SUB>)alkoxy, provided that R<SUB>3 </SUB>and R<SUB>4 </SUB>are not both OH or (C<SUB>1-5</SUB>)alkoxy; R<SUB>5 </SUB>represents H, OH, (C<SUB>1-5</SUB>)alkyl or (C<SUB>1-5</SUB>)alkoxy; and wherein R<SUB>0 </SUB>preferably represents a cinnamoyl residue; or pharmaceutically acceptable salts thereof.
Patent ES-2387981-T3 (ES)
Title: Composición y actividad antiviral de derivados de piperazina azaindoloxoacética sustituidos
Inventor: WANG TAO
IPC: C07D471/04
Filed: 2002-01-02
Granted: 2012-10-05
Abstract: Un compuesto de Fórmula I, incluyendo sales farmacéuticamente aceptables del mismo,en la que:Q esy entonces R2 está seleccionado entre el grupo que consiste en hidrógeno, halógeno y metoxi; yR3 es hidrógeno;o Q es:y R2 es halógeno o hidrógeno y R3 es hidrógeno; R4 es B;B está seleccionado entre el grupo que consiste en fenilo sustituido, heteroarilo sustituido y C(O)R7 en la que dichoheteroarilo está opcionalmente sustituido y fenilo está sustituido con uno a tres halógenos iguales o diferentes o deuno a dos sustituyentes iguales o diferentes seleccionados entre el grupo F;F está seleccionado entre el grupo que consiste en alquilo (C1-6), cicloalquilo (C3-6), arilo, heteroarilo, heteroalicíclico,hidroxi, alcoxi (C1-6), tioalcoxi (C1-6), ciano, halógeno, carbonilo, bencilo, -NR42C(O)-alquilo (C1-6), -NR42C(O)-cicloalquilo (C3-6), -NR42C(O)-arilo, -NR42C(O)-heteroarilo, -NR42C(O)-heteroalicíclico, un N-amido cíclico, -NR42S(O)2-alquilo (C1-6), -NR42S(O)2-cicloalquilo (C3-6), -NR42S(O)2-arilo, -NR42S(O)2-heteroarilo, -NR42S(O)2-heteroalicíclico, -S(O)2 NR42R43, NR42R43, alquil (C1-6)C(O)NR42R43, C(O)NR42R43, NHC(O)NR42R43, OC(O)NR42R43,NHC(O)OR54, alquil (C1-6)NR42R43, COOR54 y alquil (C1-6)COOR54 en la que dicho alquilo (C1-6), cicloalquilo (C3-6),arilo, heteroarilo, heteroalicíclico, alcoxi (C1-6), están opcionalmente sustituidos con uno a tres halógenos iguales odiferentes o de uno a dos sustituyentes iguales o diferentes seleccionados entre el grupo G;G está seleccionado entre el grupo que consiste en alquilo (C1-6), cicloalquilo (C3-7), arilo, heteroarilo, heteroalicíclico,hidroxi, alcoxi (C1-6), tioalcoxi (C1-6), tioariloxi, ciano, halógeno, nitro, carbonilo, tiocarbonilo, bencilo, -NR48(O)-alquilo(C1-6), -NR48C(O)-cicloalquilo (C3-6), -NR48C(O)-arilo, -NR48C(O)-heteroarilo, -NR48C(O)-heteroalicíclico, un N-amidocíclico, -NR48S(O)2-alquilo (C1-6), -NR48S(O)2-cicloalquilo (C3-6), -NR48S(O)2-arilo, -NR48S(O)2-heteroarilo, -NR48S(O)2-heteroalicíclico, sulfonilo, -S(O)2 NR48R49, NR48R49, (C1-6)alquilo C(O)NR48R49, C(O)NR48R49, NHC (O)NR48R49,OC(O)NR48R49, NHC(O)OR54, alquil (C1-6)NR48R49, COOR54 y alquil (C1-6)COOR54;R1 es hidrógeno;m es 2;R5 es hidrógeno;R6 no existe;R7 está seleccionado entre el grupo que consiste en arilo, heteroarilo y heteroalicíclico, en la que dicho arilo,heteroarilo y heteroalicíclico están opcionalmente sustituidos con uno a tres halógenos iguales o diferentes o conuno a dos sustituyentes iguales o diferentes seleccionados entre el grupo F
Patent ES-2252460-T3 (ES)
Title: Recipiente portafiltro para una cafeteria y procedimiento para elaborar una bebida de cafe.
Inventor: DE LONGHI GIUSEPPE
IPC: A47J31/06
Filed: 2002-05-10
Granted: 2006-05-16
Abstract: Recipiente portafiltro (1) de una cafetera, que comprende un distribuidor (3), acoplado con dicho filtro (2) y que presenta una salida de pulverización (34, 18) que se extiende sustancialmente en paralelo con respecto a la superficie de una pared de filtrado (13) de dicho filtro, adecuado para pulverizar una bebida de café contra una superficie lateral que se extiende sustancialmente en perpendicular con respecto a dicha superficie de una pared de filtrado (13) de dicho filtro, caracterizado porque dicha superficie lateral es definida por las roscas de un buje dispuesto en la parte delantera de dicha salida.
Patent ES-2289106-T3 (ES)
Title: Tubo protegido de materia plastica y procedimiento de fabricacion de dicho tubo.
Inventor: DEHENNAU CLAUDE
IPC: B29C48/21
Filed: 2002-04-25
Granted: 2008-02-01
Abstract: Procedimiento para la producción de un tubo de capas múltiples de materia plástica, protegido del deterioro de sus propiedades durante su uso y su manipulación, caracterizado porque: a) se aplica una primera capa de protección sobre un mandril tubular a base de una composición polimérica por enrollamiento de al menos un espesor de cintas de composición polimérica no orientada compatible con la composición polimérica de la materia plástica subyacente; b) se aplica seguidamente por sobreextrusión una segunda capa de protección que comprende una composición polimérica no orientada, que forma capa de acabado externa, comprendiendo el indicado mandril: - bien sea una composición polimérica de estructura biorientada - bien una composición polimérica de estructura no orientada provista en superficie de una capa de refuerzo constituida por al menos dos espesores de cintas de refuerzo que comprenden una composición polimérica orientada.
Patent ES-2271270-T3 (ES)
Title: Galleta para la confiteria helada.
Inventor: JUSTI HOLGER WERNER
IPC: A23L7/126
Filed: 2002-06-13
Granted: 2007-04-16
Abstract: Un procedimiento para la fabricación de una galleta reconstituida, en la cual: - se procede a calentar una mezcla que comprende de 50 a 75 partes de grasa, la cual es sólida a la temperatura ambiente, y de 20 a 40 partes de hidratos de carbono, a una temperatura y durante un período de tiempo, que sean suficientes como para asegurar la fusión de la grasa, - se mezclan de 60 a 90 partes de la mezcla precedente, con 10 a 30 partes de partículas de galleta, - la mezcla, se enfría, mediante agitación, a una temperatura inferior a la del punto de fusión de la grasa, - se procede a preparar un jarabe, calentando, mediante agitación, una mezcla que comprende de 50 a 80 partes de por lo menos un hidrato de carbono, de 20 a 50 partes de agua, de 2 a 10 partes de grasa, la cual es sólida a la temperatura ambiente, y de 0, 01 a 5 partes de por lo menos un emulsionante, a una temperatura y durante un transcurso de tiempo que sean suficientes como para asegurar la disolución y emulsión de los ingredientes, - el jarabe de esta forma preparado a una temperatura inferior al punto de fusión de la grasa de la mezcla que comprende las partículas de galleta, se enfría, - se mezclan de 40 a 80 partes de la mezcla que comprende las partículas de galleta, con 20 a 60 partes del jarabe, de tal forma que se obtenga una masa maleable, - se forma la masa, en la forma de una galleta, - y se procede a endurecer la galleta obtenida, mediante la evaporación del agua contenida, de tal forma que se obtenga un producto que tenga una humedad comprendida entre un 1 y un 5%.
Patent ES-2330730-T3 (ES)
Inventor: LOIBL GREGORY H
IPC: F25D3/10
Filed: 2002-03-01
Granted: 2009-12-15
Abstract: A method and device for rapidly changing at least one of the temperature and the state of a liquid in a container is provided. The container is rapidly rotated about its longitudinal axis. A source of a thin film of a medium having a different temperature than the liquid in the container is provided to thermally affect the container while rotating the container. The container is positioned at an angle to the horizontal of less than 45°, and the position of the container with respect to the thin film source is controlled by angling the axis of the container skewed from the axis of the rotating mechanism. The device can be used to cool liquids such as beverages, warm liquids such as infant formula, and/or make ice cream.
Patent ES-2256509-T3 (ES)
Inventor: GERKEMA MARKUS
IPC: C07C51/02
Filed: 2002-08-23
Granted: 2006-07-16
Abstract: The invention relates to a method for the preparation of lactic acid and calcium sulphate, in which (a) an aqueous solution that contains lactate is reacted with sulphuric acid at a temperature that is essentially higher than the transition temperature of calcium sulphate dihydrate (CaSO4.2H2O), with the formation of a mixture that contains calcium sulphate hemihydrate and lactic acid, (b) the mixture from step (a) is subjected to at least one recrystallisation step at a temperature that is essentially lower than the transition temperature of calcium sulphate dihydrate, with the formation of a precipitate of calcium sulphate dihydrate and an aqueous solution of lactic acid, and (c) the precipitate of calcium sulphate dihydrate is separated off from the aqueous solution of lactic acid.
Patent ES-2369846-T3 (ES)
Inventor: THOMAS ANNE CHRISTINE
IPC: C12N5/02
Filed: 2002-05-03
Granted: 2011-12-07
Abstract: A composition and method for enhancing cell growth and increasing the density of cell cultures containing lentivirus-infected host cells comprises adding a suitable quantity of an antibiotic to the culture to destroy harmful bacteria.
Patent ES-2311635-T3 (ES)
Inventor: SMITH TERENCE
IPC: A61K31/4436
Filed: 2002-12-06
Granted: 2009-02-16
Abstract: The present invention relates to compositions comprising 1,2-dihydropiridin-2-one compounds and an immunoregulatory or anti-inflammatory agent. The compositions are useful for the prevention or the treatment of neurodegenerative diseases, for example demyelinating disorders.
Patent ES-2272788-T3 (ES)
Inventor: CHRISTENSEN FLEMMING H
IPC: A22B7/00
Filed: 2002-10-10
Granted: 2007-05-01
Abstract: An apparatus for cutting middles comprises a mainly linear conveyor with conveyor elements (15) for seizing and holding a middle by the spinal column (11) and moving it in the lengthways direction of the spinal column. The middle is moved while being held with the split surface of the spinal column in contact with mainly horizontal surfaces (6) on the conveyor elements (15) and the inner side (20) of the spinal column in contact with oblique surfaces (8) on the elements, and with the spinal column pressed into the wedge-shaped openings which the horizontal surfaces (6) and the oblique surfaces (8) form together. The apparatus has a cutting device (32) for cutting the middle in mainly the lengthways direction of the spinal column during the transport of the middle past the device. The apparatus has a measurement system (21, 29) located upstream of the cutting device (32) which system is designed to measure horizontal positions on the inner surface (20) of the middle a pre-determined distance below the horizontal surfaces (6) of the conveyor elements (14) while the middle is conveyed past the measuring system. It also comprises a calculation unit designed to convert measurement data from this system into control signals and drive means arranged to adjust the positions of the cutting device (32) as a function of the control signals in a plane perpendicular to the transport direction of the middle during transport of the middle past the device. The apparatus detects how much the spinal column has been overcut or undercut during splitting, i.e. it calculates by how much the spinal column is too high or too low in the apparatus compared to the correct cutting position. By means of this information the height of the cutting device can be automatically adjusted to permit a correct cut to be made in the middle.
Patent ES-2266616-T3 (ES)
Inventor: MAECKE HELMUT ROBERT
IPC: C07K14/655
Filed: 2002-08-07
Granted: 2007-03-01
Abstract: The present invention relates to novel somatostatin analogues of the general formula: <CHEM> wherein Z may be absent or present and when present is selected from the group consisting of DOTA- and DTPA-based chelators, NOTA-based chelators, carbonyl compounds, hydrazino nicotinamide (hynic) , N4 -chelators, desferrioxamin, NxSy-chelators, all optionally complexed or labeled with a radioisotope, Tyrosine (Tyr) for halogenation, a fluorescent dye or biotin; L may or may not be present and is a linker molecule; X1 is a symmetric or asymmetric diamino acid, containing 3 or 4 consecutive C atoms with a linker to the chelating agent, for example D/L-diamino butyric acid (D/L-Dab) for a more basic character or D/L-Glu for coupling to primary and secondary amino groups; X2 is a positively charged natural or unnatural amino acid or arginine mimic or citrulline, or a neutral amino acid like Asn; X3 is phenylalanine (Phe), Ala- Ä3- (2-thienyl) Ü or  alpha '-, beta -naphthylalanine; X4 is an aromatic amino acid, optionally halogenated, in particular with Cl, Br, I or <18>F.; X5 is threonine (Thr) or serine (Ser); and X6 is phenylalanine (Phe), Ala-Ä3 -(2-thienyl)Ü Ü or  alpha -, beta -naphthylalanine.
Patent ES-2673820-T3 (ES)
Title: Artículos de vidrio producidos ajustando las características de temperatura del vidrio
Inventor: PECORARO GEORGE A
IPC: C03C3/087
Filed: 2002-10-03
Granted: 2018-06-25
Abstract: Una composición de vidrio, que comprende: SiO2 del 70 al 75 por ciento en peso, Na2O del 12 al 15 por ciento en peso, K2O del 0 al 2 por ciento en peso, CaO del 10 al 10,5 por ciento en peso, MgO del 2 al 3 por ciento en peso, Al2O3 del 0 al 2 por ciento en peso, SO3 del 0 al 1 por ciento en peso, Fe2O3 del 0 al 2 por ciento en peso, con la condición de que: Na2O + K2O sea del 12 al 15 por ciento en peso, CaO/MgO no más del 5.
Patent ES-2247422-T3 (ES)
Inventor: DELAGE JEAN-PIERRE
IPC: B60T11/236
Filed: 2002-12-24
Granted: 2006-03-01
Abstract: When an element of the electro-hydraulic brake circuit ( 1 ) is malfunctioning, a master cylinder ( 2 ) can brake the vehicle. A brake actuation simulator ( 8 ) is then disconnected from the master cylinder ( 2 ) by means of an O-ring gasket ( 22 ) after the gasket has been compressed between a groove ( 16 ) in a secondary piston ( 11 ) and a bore ( 24 ) in the master cylinder. In order to prevent the gasket from being extruded from the groove during brake release (or brake pedal release) resulting from sudden braking, the invention makes provision for a pressure relief duct ( 32 ) to be provided inside the secondary piston. Extra pressure can then be discharged during brake release (or brake pedal release) through the brake release duct ( 32 ) from the inside of the chamber ( 30 ) of the simulator towards the primary chamber ( 10 ) of the master cylinder.
Patent ES-2283656-T3 (ES)
Inventor: KREUZER BERND
IPC: B65G49/04
Filed: 2002-02-20
Granted: 2007-11-01
Abstract: The workpiece handling device handles vehicle chassis (22). It is of modular construction. The first module has a handling line, one or several handling regions (14) and a guide device along the line. The second module has one or more carriages (20b. 20c) for the workpieces. The carriages can move along the guide device.
Patent ES-2288202-T3 (ES)
Title: Recipiente sellado.
Inventor: TSAUR GARRY
IPC: B65D83/00
Filed: 2003-04-28
Granted: 2008-01-01
Abstract: Un recipiente sellado que comprende: un alojamiento alargado (1) con dos extremos longitudinales que están sellados y con uno o más medios (2) de apertura; un separador (3; 6) que separa longitudinalmente el alojamiento (1) alargado en un primer compartimiento continuo y un segundo compartimiento continuo, siendo el separador (3; 6) más corto que el alojamiento alargado (1) para permitir la libre circulación de fluido (4) entre el primer y el segundo compartimiento continuo en ambos extremos longitudinales del alojamiento (1) alargado; usándose el recipiente sellado para almacenar fluido (4) hasta que el fluido (4) es liberado a través de los medios de apertura.
Patent ES-2256619-T3 (ES)
Inventor: BRAHM MARTIN DR
IPC: C08G18/18
Filed: 2003-06-20
Granted: 2006-07-16
Abstract: Catalytic trimerisation of diisocyanate containing at least80 wt.% 2,4- and/or 2,6- diisocyanatotoluene (TDI) to give an isocyanurate containing below 0.1 wt.% monomeric diisocyanate is effected while adding 0.1-25 wt.% (based on diisocyanate) of additional 2,4-TDI and ending reaction optionally by poisoning the catalyst.  Solvent- and isocyanurate group-containing polyisocyanates based on 2,4- and/or 2,6-diisocyanatotoluene (TDI) and with a monomeric diisocyanate content below 0.1 wt.% are obtained by catalytically trimerizing a mixture of diisocyanate (20-80 wt.%) containing at least80 wt.% 2,4- and/or 2,6-TDI; solvent (20-80 wt.%; an alcohol component (0-20 wt.%); and a dialkylaminomethyl group-containing phenolic catalyst at 20-120degreesC while adding 0.1-25 wt.% (based on diisocyanate) of additional 2,4-TDI and ending reaction optionally by poisoning the catalyst.
Patent ES-2248690-T3 (ES)
Inventor: HETHERINGTON RAY
IPC: C08K5/00
Filed: 2003-07-25
Granted: 2006-03-16
Abstract: A curable fluoroelastomer composition comprising at least one fluoroelastomer, a bisphenol curative, and a peroxide curative provides a non-post cure flurorelastomer material suitable for use in the manufacture of, for example. When cured (vulcanized), the composition exhibits an improved compression set resistance, in comparison to the fluoroelastomer cured by the bisphenol curative alone, without performing a post-cure procedure. <IMAGE>
Patent ES-2295574-T3 (ES)
Inventor: LICARI PETER J
IPC: C12N1/21
Filed: 2003-02-25
Granted: 2008-04-16
Abstract: The present invention provides a generalized oxygen-limited cultivation method for myxobacterial strains engineered to heterologously express polyketides synthase (PKS) gene clusters under various oxygen tension conditions, modulating the polyketide congener distribution.
Patent ES-2298559-T3 (ES)
Inventor: VAUGHAN JOSEPH S
IPC: B65D17/34
Filed: 2003-09-19
Granted: 2008-05-16
Abstract: The present invention relates to an improved opening end closure which is adapted for interconnection to a beverage container to prevent premature rupturing and detachment of the tear panel from the center panel. More specifically, the present invention includes an improved cent bead, an enlarged score origination loop, and a pull tab with a cut-out portion with one leg longer than the other leg for selectively orienting the direction of force created on the tear panel away from the hinge portion of the tear panel.
Patent ES-2320988-T3 (ES)
Inventor: SPEELMANS GELSKE
IPC: A23L29/00
Filed: 2003-06-20
Granted: 2009-06-01
Abstract: The present invention relates to a method of preventing or alleviating symptoms of malabsorption in a monogastric mammal which malabsorption is caused by impaired intestinal digestion, said method comprising the enteral administration to said mammal of an effective amount of one or more strains of the genus  Propionibacterium  optionally together with a prebiotic that stimulates gastrointestinal activity of  Propionibacterium.   Another aspect of the invention relates to a dietary supplement comprising at least 10 6  metabolically active cells of the genus  Propionibacterium;  at least 0.5 g of a prebiotic and/or at least 10 6  metabolically active homo fermentative cells of the genus  Lactobacillus  and/or at least 10 6  metabolically active cells of the genus  Bifidobacterium;  and a nutritionally acceptable carrier.
Patent ES-2288629-T3 (ES)
Inventor: FUHR GUNTER
IPC: A01N1/02
Filed: 2003-11-05
Granted: 2008-01-16
Abstract: The carrier (10) for a sample chamber, especially for the preservation of biological samples at very low temperatures, has a holding frame (20) in two sections (30,40) to position the chambers.  The carrier (10) for a sample chamber, especially for the preservation of biological samples at very low temperatures, has a holding frame (20) in two sections (30,40) to position the chambers. The sections are held together by a release lock (50), with their side surfaces (31,41) against each other and the sample chamber secured between them. The side surfaces are profiled so that, when they are flush against each other, holders (21-25) are formed to take the sample chambers in fixed positions.
Patent ES-2251703-T3 (ES)
Inventor: HOHE HANS-PETER
IPC: H02H3/32
Filed: 2003-08-14
Granted: 2006-05-01
Abstract: The invention relates to a method for monitoring fault currents in an electric AC mains having a predetermined mains frequency. According to the invention, current values of electric currents to be monitored are recorded (12a 12d), after which the recorded current values are converted into digitized current values (14). Afterwards, these digitized current values are used to calculate (16) cumulative current values, from which blocks comprised of the cumulative current values are formed (18) according to the phase position of a mains voltage signal. The blocks are then split (24) into spectral components. The spectral components of the blocks are then monitored (36) with regard to an exceeding of spectral limit values in order to evaluate the danger of the fault current.
Patent ES-2320443-T3 (ES)
Inventor: NAKAMURA YUSUKE
IPC: C12N15/113
Filed: 2003-09-12
Granted: 2009-05-22
Abstract: Objective methods for detecting and diagnosing pancreatic cancer (PNC) are described herein. In one embodiment, the diagnostic method involves determining the expression level of PNC-associated gene that discriminates between PNC cells and normal cells. The present invention further provides methods of screening for therapeutic agents useful in the treatment of pancreatic cancer, methods of treating pancreatic cancer and method of vaccinating a subject against pancreatic cancer.
Patent ES-2268491-T3 (ES)
Inventor: FUCHS RAINER
IPC: A01N43/56
Filed: 2003-11-22
Granted: 2007-03-16
Abstract: Pyrazoline carboxanilides (I) are new.  Pyrazoline carboxanilides of formula (I) are new:  R1  =  halo;  R2, R3  =  CN, halo, haloalkyl, haloalkoxy, alkylthio, haloalkylthio, alkylsulfinyl, haloalkylsulfonyl, alkylsulfonyl or haloalkylsulfonyl;  R4  =  cyanoalkyl. An Independent claim is also included for the preparation of (I).
Patent ES-2254997-T3 (ES)
Inventor: GALASSI CESARINO
IPC: B65D75/32
Filed: 2001-03-28
Granted: 2006-06-16
Abstract: Process for the production of plastic blister packs (13) containing liquid perfumes, wherein forming and sealing are carried out by using a horizontal apparatus, in which for the transport of the films (2 and 6) the fluid of the hydraulic circuit is replaced with air including oil.
Patent ES-2449716-T3 (ES)
Title: Estructura de marco para un reactor electroquímico de tipo filtro prensa
Inventor: SIOLI GIANCARLO
IPC: H01M8/02
Filed: 2004-03-30
Granted: 2014-03-20
Abstract: Componente estructural para celdas electrolíticas de un reactor electroquímico de tipo filtro prensa,que comprende un marco (6) que sirve de soporte para su elemento funcional correspondiente (7, 7a) elegido entreuna lámina bipolar y, respectivamente, un diafragma, comprendiendo dicho marco (6) un primer marco anular (8) yun segundo marco anular (9), siendo ambos estructuralmente independientes uno del otro y estando acopladosentre sí, coaxialmente, uno dentro del otro, estando dicho primer marco anular (8) y dicho segundo marco anular (9)hechos de materiales diferentes, siendo el material del primer marco anular (8) principalmente resistente a lacorrosión por agentes químicos, y estando hecho el material de dicho segundo marco anular (9) de materialcompuesto principalmente resistente a las altas presiones de trabajo de dicho reactor (1).