baber/WOPTO huggingface dataset:
Patent CA-3185336-A1 (CA)
Title: Small molecule drugs and related methods for treatment of diseases related to a.beta.42 oligomer formation
Inventor: SINGH AMBUJ K
IPC: C07C211/29
Filed: 2018-11-05
Abstract: The present invention provides small molecule drugs and pharmaceutical compositions for the treatment and prevention of diseases related to the formation of A1342 oligomers in a subject. It further provides a method ofreducing formation of or disrupting A(342 oligomers in a subject, the method comprising the step of administering to the subject in need thereof a therapeutically effective amount of a pharmaceutical composition.
Patent CA-3189028-A1 (CA)
Title: Constructing and programming quantum hardware for quantum annealing processes
Inventor: MOHSENI MASOUD
IPC: G06N20/00
Filed: 2014-12-31
Abstract: Quantum adiabatic computations may become non-adiabatic due to excitations caused, e.g., by thermal fluctuations. Instead of remaining at the instantaneous ground state, the evolving quantum state initially started at the ground state of the initial Hamiltonian can reach an excited state of the evolving Hamiltonian. Quantum hardware may be constructed and programmed to suppress such excitations from an instantaneous ground state to a higher energy state during an early stage of the computation. Quantum hardware may further be constructed and programmed to assist relaxation from higher energy states to lower energy states or the ground state during a later stage of the computation.
Patent CA-3190123-A1 (CA)
Inventor: SCHECHNER ALEXANDER
IPC: F24F5/00
Filed: 2021-07-16
Abstract: The document describes a system for climate-control of interior spaces (4) of a building (6), which spaces are connected via at least one waste air duct (10), wherein one or more interior spaces (4) are provided with a climate-control device (34) which has an inflow (38) for external air, which inflow provides fresh air or recirculated air to the interior space(s) (4), and which is connected to a fluid circuit (32) of a heat pump (30), wherein the waste air duct (10) and a further fluid circuit (28) of the heat pump are connected to an energy accumulator (14) arranged outside the building (6), wherein the energy accumulator (14) is designed for energy transfer and for energy storage with a heat exchanger (18) in a liquid reservoir (16), which is connected to the further fluid circuit (28) of the heat pump (30) via the heat exchanger (18), wherein the waste air is guided into the liquid reservoir (16) via a heat exchanger (26).
Patent CA-3190804-A1 (CA)
Title: Proteines de fusion comprenant des proteines de lait et leurs compositions
Inventor: JOHNSON TIMOTHY SCOTT
IPC: C12N9/08
Filed: 2021-08-05
Abstract: La présente invention concerne d'une manière générale une protéine recombinante, des compositions comprenant une telle protéine recombinante, et des procédés de production d'une telle protéine recombinante et de telles compositions.
Patent CA-3197920-A1 (CA)
Inventor: BROUGH DOUGLAS E
IPC: A61K47/42
Filed: 2021-11-23
Abstract: Provided herein are multi-antigenic human papilloma virus (HPV) molecular vaccine constructs for use and treatment of HPV associated disorders and pathologies; such as HPV molecular vaccines targeting HPV6 and HPVll associated pathologies.
Patent CA-3198712-A1 (CA)
Title: Method and system for preparing blanks for forming cartons
Inventor: WALSH JOSEPH C
IPC: B65D5/06
Filed: 2021-10-14
Abstract: A method of preparing a blank for forming a carton includes obtaining a blank, positioning the blank in a blank feeder assembly of a system for preparing blanks, moving the blank from the blank feeder assembly to a conveyor assembly of the system, and activating the conveyor assembly to move the blank along a coating applicator assembly of the system, the coating applicator assembly having a container defining a reservoir holding a volume of a coating and an applicator wheel rotatably supported at least partially in the reservoir of the coating applicator assembly. The method further includes applying a portion of the coating from the reservoir to a portion of the blank.
Patent CA-3200268-A1 (CA)
Inventor: HSU CHE-WEI
Filed: 2023-05-23
Abstract: A torque sensor includes a sleeve member configured to be mounted on a center shaft, and a tubular sensor body arranged coaxially with the sleeve member. At least one outer surface of the sleeve member includes one or more magnetostrictive elements. The tubular sensor body includes a bobbin for mounting a sensor coil. An induced current in the sensor coil is detected in response to pedaling by a user. The tubular sensor body includes one or more inclined surfaces inclined with respect to a radial direction of the torque sensor, the one or more inclined surfaces being coupled with the sleeve member or the center shaft.
Patent CA-3201369-A1 (CA)
Inventor: GOVER CHRISTOPHER
IPC: F02C7/32
Filed: 2023-05-17
Abstract: A gas turbine engine assembly includes an engine core and an electric machine. The engine core includes a first rotating structure, a second rotating structure, a combustor and a flowpath. The first rotating structure includes a first structure turbine rotor. The second rotating structure includes a second structure compressor rotor, a second structure turbine rotor and a second structure shaft connecting the second structure compressor rotor to the second structure turbine rotor. The second structure compressor rotor, the combustor, the second structure turbine rotor and the first structure turbine rotor are arranged sequentially along the flowpath. The electric machine is arranged within the engine core. The electric machine includes an electric machine rotor and an electric machine stator adjacent the electric machine rotor. The electric machine rotor is rotatable with the second rotating structure and located between the second structure compressor rotor and the first structure turbine rotor.
Patent CA-3201491-A1 (CA)
Inventor: GROVER MATTHEW
IPC: H04N21/434
Filed: 2021-11-12
Abstract: In one aspect, a method includes transmitting a request for supplemental content tor use by a content-presentation device that is scheduled to perform a content-modification operation at a start-time and, in response to the request: receiving, into a first buffer of the content- presentation device, first supplemental content having a first video quality that is higher than or equal to a predefined threshold, and receiving, into a second, different buffer of the content- presentation device, second supplemental content having a second video quality lower than the predefined threshold. The method also includes within a predefined time period before the start-time, determining whether an entirety of the first supplemental content has been received into the first buffer. The method also includes based on the determination, selecting supplemental content from a set of supplemental content that includes the first and second supplemental content, and performing the content-modification operation using the selected supplemental content.
Patent CA-3202485-A1 (CA)
Inventor: BHASKAR KARTHIK
IPC: A61M5/38
Filed: 2021-12-22
Abstract: Un dispositif de ventilation d'air peut comprendre un adaptateur comprenant un corps tubulaire ayant un intérieur creux définissant un trajet d'écoulement de fluide, et un bouchon d'évent couplé de façon détachable à au moins une partie du corps tubulaire. Le bouchon d'évent peut comprendre une surface circonférentielle interne définissant une chambre interne du bouchon d'évent, et le trajet d'écoulement de fluide de l'adaptateur peut mettre en communication fluidique l'adaptateur avec la chambre interne du bouchon d'évent. Le bouchon d'évent peut en outre comprendre un matériau polymère superabsorbant disposé dans la chambre interne. Le matériau polymère superabsorbant peut être configuré pour (i) absorber un liquide entrant dans la chambre interne à partir du trajet d'écoulement de fluide, et (ii) se dilater en volume lorsque le liquide est absorbé dans le matériau polymère superabsorbant. L'air entraîné dans le liquide entrant dans la chambre interne peut être évacué vers l'extérieur du dispositif de ventilation d'air par l'intermédiaire du bouchon d'évent.
Patent CA-3204768-A1 (CA)
Inventor: JORGE TIAGO MIGUENS RIJO BRANCO
IPC: G05D1/02
Filed: 2021-12-21
Abstract: L'invention concerne un dispositif de manipulation de charge pour lever et déplacer un ou plusieurs conteneurs empilés dans un système de stockage comprenant une structure de cadre de grille supportant une pluralité de pistes agencées selon un motif de grille pour définir une structure de grille au-dessus du ou des empilements de conteneurs, le motif de grille comprenant une pluralité de cellules de grille et chacun du ou des empilements de conteneurs étant situé à l'intérieur d'une empreinte d'une seule cellule de grille, le dispositif de manipulation de charge comprenant : i) un ensemble de roues comprenant une première et une seconde paire de roues ; l'ensemble de roues étant entraîné par un mécanisme d'entraînement ; ii) un dispositif de levage pour soulever un conteneur de stockage de l'un des empilements de conteneurs dans un espace de réception de conteneur du dispositif de manipulation de charge ; iii) un moyen de détection de position pour la mesure de la position du dispositif de manipulation de charge par rapport à la structure de grille ; iv) un dispositif de commande en communication avec le moyen de détection de position et le mécanisme d'entraînement, le dispositif de commande étant configuré pour commander le mouvement du dispositif de manipulation de charge d'une position actuelle à une position commandée sur la structure de grille par : a) la détermination d'une demande de couple d'anticipation sur l'ensemble de roues à un instant donné à partir d'un profil de commande de mouvement prédéterminé ; b) la compensation de la demande de couple d'anticipation à partir d'une position mesurée du dispositif de manipulation de charge sur la structure de grille à l'instant donné pour calculer une demande de couple sur l'ensemble de roues.
Patent CA-3204788-A1 (CA)
Title: Antibodies comprising an antigen-binding site that specifically binds to two different epitopes and methods of making them
Inventor: FUH GERMAINE
IPC: C07K16/24
Filed: 2014-12-18
Abstract: The invention provides dual specific antibodies and methods of making and using such antibodies. In general, the dual specific antibodies are generated by identification of a monospecific antibody having light chain variable region VL residues that are electrostatic or hydrophobic and altering the nucleic acid sequence encoding one or more solvent accessible residues in the VH of the antibody either alone or in combination with alteration of the nucleic acid sequence encoding the VL of the antibody. The altered VH and the VL are expressed and dual specific antibodies, or antigen-binding fragments thereof, are selected. Exemplary dual specific antibodies are also provided as well as methods of using the antibodies.
Patent CA-3205168-A1 (CA)
Inventor: MALJUSCH ARTJOM
IPC: C08G65/40
Filed: 2022-01-10
Abstract: La présente invention concerne des composés (polymères) et un procédé de préparation de ces derniers. L'invention est destinée à être utilisée dans le domaine de l'électrochimie. Les propriétés conductrices d'anions des composés divulgués, rendent ce matériau approprié pour la préparation de membranes conductrices d'anions. L'objet de la présente invention est de fournir un matériau facile à préparer, présentant des propriétés conductrices d'anions appropriées et un gonflement contrôlé. Des précurseurs peu coûteux doivent être utilisés pour la synthèse. Ce problème a été résolu par la fourniture de composés caractérisés par au moins une unité de formule (I) avec X étant un élément de structure comprenant au moins un atome d'azote avec une charge positive liée à C1 et à C2 et lié par l'intermédiaire de deux liaisons à un ou deux radicaux hydrocarbonés, comprenant de 1 à 12 atomes de carbone et Z étant un élément de structure comprenant un atome de carbone lié à C3 et à C4 et au moins un noyau aromatique à 6 chaînons lié directement à l'un des atomes d'oxygène, ledit cycle aromatique à 6 chaînons étant substitué en position 3 et 5 par un groupe alkyle identique ou différent ayant de 1 à 4 atomes de carbone
Patent CA-3207590-A1 (CA)
Inventor: ZHANG XUEJUN
IPC: C07D471/04
Filed: 2022-02-08
Abstract: A pyridopyrimidinone derivative as represented by formula I, and a tautomer, a stereoisomer, a hydrate, a solvate, a pharmaceutically acceptable salt thereof or a prodrug thereof. The pyridopyrimidinone derivative has a good SOS1 inhibitory effect.
Patent CA-3207714-A1 (CA)
Title: Pyrrolopyridine derivative preparation method
Inventor: KIM KYUNGJIN
IPC: C07D471/04
Filed: 2021-01-11
Abstract: The present invention relates to a method for preparing a pyrrolopyridine derivative compound exhibiting antiviral activity, and a novel intermediate used therein. The preparation method of the present invention enables reaction steps to be reduced through effective process development and a high purity pyrrolopyridine derivative compound to be prepared in a high yield, and thus enables production costs to be remarkably reduced so as to be economical and to be suitable for mass production.
Patent CA-3208293-A1 (CA)
Inventor: MEDINA RICCARDO
IPC: B28D7/04
Filed: 2022-01-11
Abstract: An apparatus (1) for moving worked pieces (P) is described, comprising: - a piece-supporting plane (5) configured to support one or more worked pieces (P); - a first gripping device (30) and a second gripping device (40), respectively defining a first and a second gripping plane (32, 42) of a worked piece (P); wherein the apparatus (1) is configured to move the first and the second gripping device (30, 40) among: i) a picking position wherein the first or the second gripping device (30, 40) is configured to pick up a worked piece (P) laid on the piece-supporting plane (5); ii) an exchange position wherein the first gripping device (30) and the second gripping device (40) are mutually oriented such that the first and the second gripping planes (32, 42) of the worked piece (P) are facing each other to allow transferring the worked piece (P) from the first gripping device (30) to the second gripping device (40), or vice versa; and iii) a laying position, wherein the second gripping device (40) or the first gripping device (30) is configured to release the worked piece (P) being transferred in the exchange position in a piece storage area (6).
Patent CA-3208929-A1 (CA)
Inventor: PRAKASH OM
IPC: G01N17/04
Filed: 2021-12-23
Abstract: A sensing instrument includes a first electrode, a second electrode that surrounds the first electrode, and a sensing module configured to sense a capacitance of a material by applying a voltage between the first electrode and the second electrode while the first electrode and the second electrode are adjacent to the material. A method of operating a sensing instrument includes applying a voltage between a first electrode and a second electrode while the first electrode and the second electrode are positioned adjacent to a material. The second electrode surrounds the first electrode. The method further includes sensing a capacitance of the material based on a response of the material to the voltage.
Patent CA-3212530-A1 (CA)
Title: Anticorps anti-cldn6 et son utilisation
Inventor: DU LIANG
IPC: A61K39/395
Filed: 2021-03-05
Abstract: L'invention concerne un anticorps anti-CLDN6 ou un fragment de liaison à l'antigène associé ; une molécule d'acide nucléique codant pour celui-ci ; un immunoconjugué, une molécule bispécifique, un récepteur antigénique chimérique et une composition pharmaceutique contenant celui-ci ; et son utilisation pour la prévention et/ou le traitement des tumeurs.
Patent CA-3212721-A1 (CA)
Title: System and method for distribution of encrypted traffic in a multiple independent level security environment
Inventor: BARELLA SCOTT
IPC: H04L9/00
Filed: 2022-05-10
Abstract: What is disclosed is: A system for delivering real-time media traffic, comprising: A secure matrix communicatively coupled to a first bidirectional node, a second bidirectional node, and a control plane, wherein the first bidirectional node is communicatively coupled to a source. The first bidirectional node and the source have a first security level. The second bidirectional node is communicatively coupled to one or more destinations, and the second bidirectional node and the one or more destinations have a second security level. The first bidirectional node transmits a first encrypted real-time traffic to the secure matrix based on a first real-time media traffic received from the source. The control plane, using flow-based programming, configures the secure matrix to direct the first encrypted real-time traffic to the second bidirectional node, wherein the directing is based on the first security level, the second security level, and a security policy.
Patent CA-3213180-A1 (CA)
Title: Illumination device and imaging device
Inventor: YOSHIDA TOHRU
IPC: A61B5/00
Filed: 2020-01-20
Abstract: An illumination device (4) for an imager for imaging a target includes an objective cover (132) including a light transmissive member to direct light from the target to the imager to allow the imager to image the target, and at least one light source (141, 142, 143) located nearer the imager than the objective cover (132) to illuminate the target through the objective cover (132). The at least one light source (141, 142, 143) is located outward from an inverted region that is a region formed by substantially inverting, toward the imager and with respect to the objective cover (132), a region defined by predetermined rays of rays nearer the target from the objective cover (132) in a pencil of rays, the pencil of rays entering, through the imaging lens (41a, 41b), the image sensor (44) from the target in contact with the objective cover (132) and in focus with the imaging lens (41a, 41b).
Patent CA-3213896-A1 (CA)
Inventor: OMURA YOSHIHITO
IPC: A61J3/00
Filed: 2022-03-03
Abstract: A drug feeder is provided which, even when a small amount of remaining drug is retained, can reduce or eliminate the factors resulting in retention of the drug. The drug feeder 10 is provided with an outside rotator 20, an inside inclined rotator 30, a width regulating mechanism 70 which aligns a solid drug carried from above the inside inclined rotator 30 onto the annular top end surface 23 of the outside rotator 20; and a drug dropping detecting means 56 which detects dropping of the drug discharged after alignment. While performing rotation control, a control unit 80 determines that the contained drug is gone when the undetected time interval has reached a final defined time interval. Before stopping the discharge operation, vibration rotation control is performed for rotating while vibrating the inside inclined rotator 30 in order to eliminate retention of any residual drug. Furthermore, in order to eliminate congestion of the drug before that, the width regulating mechanism 70 is controlled and the width of the drug conveyance path at the annular top end surface 23 is increased in stages.
Patent CA-3214147-A1 (CA)
Inventor: WEHRMEYER GERHARD
IPC: B23Q17/09
Filed: 2022-04-14
Abstract: The invention relates to a cutting wheel (103) for a tunnel boring machine, in which cutting wheel, for the purpose of monitoring the condition of at least one mining tool (112, 115, 118) during removal of a geological structure present, during tunneling, at the cutting wheel (103) in a tunneling direction, a tool condition monitoring device is provided, which device has at least one support part (121, 124, 127) which is installed separately and at a distance from the or a relevant mining tool (112, 115, 118). In the relevant support part (121, 124, 127), a current-conductor element is embedded, which is interrupted in terms of its ability to carry current after a wear limit which is characteristic of the condition of the relevant mining tool (112, 115, 118) has been reached. In this way, the condition of mining tools (112, 115, 118) can be reliably determined during a relatively simple maintenance operation or retrofitting with a support part (121, 124, 127).
Patent CA-3216546-A1 (CA)
Title: Water-soluble unit dose article including water-soluble core construction
Inventor: KNIGHT JONATHON D
IPC: C11D17/04
Filed: 2022-05-06
Abstract: A single unit dose article includes a water-soluble core substrate comprising a water- soluble resin. The water-soluble core substrate contains a carrier solvent with an active cleaning formulation, wherein upon contact of the carrier solvent with the water-soluble core substrate, the water-soluble core substrate exhibits shrinkage or swelling. Also disclosed are methods of making the single unit dose article.
Patent CA-3217131-A1 (CA)
Title: Techniques d'amplification pour la caracterisation d'acides nucleiques
Inventor: GORMLEY NIALL ANTHONY
IPC: C12Q1/6844
Filed: 2022-04-28
Abstract: L'invention concerne des techniques d'amplification d'acides nucléiques. Des modes de réalisation comprennent la génération d'acides nucléiques concaténés à l'aide d'une amplification en cercle roulant de matrices, par exemple, à partir d'un ADNc d'un ARNm pleine longueur ou à partir de matrices synthétiques, et le séquençage et/ou la détection des acides nucléiques concaténés. Dans certains modes de réalisation, la technologie de l'invention comprend des réactions d'amplification qui comprennent des interactions CRISPR-Cas qui génèrent des amorces en raison des interactions CRISPR-Cas, les amorces étant à leur tour utilisées en tant que partie de réactions d'amplification détectables. Les techniques d'amplification décrites peuvent utiliser des oligonucléotides ou des amorces synthétiques.
Patent CA-3219759-A1 (CA)
Inventor: LIMEM SKANDER
IPC: A61F2/12
Filed: 2022-05-09
Abstract: L'invention concerne des implants absorbables imprimés en 3D qui peuvent être utilisés pour reconstruire le mamelon avec des tissus régénérés, ce qui permet une meilleure satisfaction sur le plan esthétique. Les implants sont constitués de plans parallèles de filaments qui sont décalés et liés les uns aux autres pour former des réseaux macroporeux (130) avec des structures à cellules ouvertes comprenant des formes cylindriques. Le réseau macroporeux (130) peut être entouré d'une enveloppe (120) ou d'un revêtement, ou peut être au moins partiellement rempli d'un hydrogel. Les implants sont particulièrement adaptés à une utilisation dans les procédures de chirurgie plastique, par exemple pour reconstruire le mamelon après une mastectomie totale et une reconstruction mammaire.
Patent CA-3221485-A1 (CA)
Title: Display-system for displaying product or price information
Inventor: FILALI ANSARY TARIK
IPC: G06Q30/02
Filed: 2021-07-01
Abstract: A display-system for displaying product and/or price information that comprises: - at least one electronic display device to display content, which is represented by content data, - a data provision system that is arranged to provide the content data to the at least one electronic display device, - a detection stage that is designed to automatically detect a discrepancy + in the content that is intended to be displayed by the electronic display device, and/or + in the content already displayed by the electronic display device, wherein the detection stage is designed to trigger at least one action when a discrepancy is detected.
Patent CA-3223099-A1 (CA)
Title: Cobalt and/or cerium doped zeolites for bifunctional catalytic hydroisomerisation
Inventor: IIDA TAKAYUKI
IPC: C10G45/62
Filed: 2022-06-08
Abstract: Provided herein are methods for hydroisomerization of a hydrocarbon feedstock comprising contacting the hydrocarbon feedstock with hydrogen and a catalyst to yield a hydrocarbon product having an increase in branched hydrocarbons relative to the hydrocarbon feedstock. The present catalysts comprise a heteroatom-doped Beta zeolite having a trivalent cation as a framework metal oxide, an extra-framework species comprised of cerium and/or cobalt, and from 0.01 to 1.5 wt.% of a group VIII or VIB metal, or a combination thereof.