baber/WOPTO huggingface dataset:
Patent CA-2445412-A1 (CA)
Title: High performance jack for telecommunication applications
Inventor: RUETSCH RANDOLPH
IPC: H01R12/58
Filed: 2003-10-17
Abstract: The present invention relates to an electrical connector for telecommunications applications, including a circuit board and first and second electrical contacts, extending from the circuit board along first and second paths, respectively, the second path crossing the first path. A third electrical contact extends from the circuit board along a third path, and-a fourth electrical contact extends from the circuit board along a fourth path, the fourth path crossing the third path. At least four electrical terminals extend from the circuit board and at least four electrically conductive traces on the circuit board electrically couple each of the first, second, third and fourth electrical contacts to a respective electrical terminal.
Patent CA-2445746-A1 (CA)
Inventor: JENSEN MICHAEL
IPC: A61K39/00
Filed: 2002-04-30
Abstract: La présente invention concerne des immunorécepteurs chimériques transmembranaires, désignés sous le nom de "zétakines", comprenant un domaine extracellulaire contenant un ligand récepteur soluble lié à une région support pouvant fixer le domaine extracellulaire à une surface cellulaire, une région transmembranaire et un domaine de signalisation intracellulaire. Les zétakines, lorsqu'elles sont exprimées sur la surface des lymphocytes T, dirigent l'activité des lymphocytes T vers les cellules spécifiques exprimant un récepteur pour lequel le ligand récepteur soluble est spécifique. Les immunorécepteurs chimériques de zétakine représentent une nouvelle extension des immunorécepteurs basés sur des anticorps servant à rediriger la spécificité antigénique des lymphocytes T, et peuvent être utilisés dans le traitement de divers cancers, en particulier via les systèmes à cytokines autocrines/paracrines utilisés par les affections malignes humaines. Dans un mode de réalisation préféré, l'invention concerne un immunorécepteur spécifique au gliome comprenant le domaine extracellulaire cible du mutant IL-13 spécifique au IL-13R.alpha.2 IL-13(E13Y) lié à la région Fc de l'IgG, le domaine transmembranaire de la CD4 humaine, et la chaîne zéta CD3 humaine.
Patent CA-2446051-A1 (CA)
Title: Phthalazine derivatives with angiogenesis inhibiting activity
Inventor: BOLD GUIDO
IPC: A61P27/02
Filed: 2002-05-03
Abstract: The invention relates to new phthalazine derivatives of formula (I), wherein R1 and R2: a) are independently in each case a lower alkyl; b) together form a bridge of subformula (I*), wherein the bond is achieved via the two terminal C atoms and m is 0 to 4; or c) together form a bridge of subformula (I**), wherein one or two of the ring members T1, T2, T3 and T4 are nitrogen, and t he others are in each case CH, and the bond is achieved via atoms T1 and T4; A, B, D, E and T are independently N or CH subject to the proviso that at least one and not more than three of these radicals are N; X is imino, oxa, or thi a; Y is hydrogen, substituted or unsubstituted aryl, substituted or unsubstitut ed heteroaryl, or unsubstituted or substituted cycloalkyl; and wherein the bond s characterized in subformula (I*) by a wavy line are either single or double bonds; to an N-oxide of a compound of formula I; a tautomer or mixture of tautomers of a compound of formula (I) of an N-oxide thereof; and a pharmaceutically acceptable salt of a compound of formula (I), of an N-oxide or of a tautomer ormixture of tautomers thereof; processes for their preparation and pharmaceutical uses.
Patent CA-2447245-A1 (CA)
Inventor: HUANG XIAOJUN
IPC: G01V1/48
Filed: 2003-10-28
Abstract: Divulgation d'une méthode pour déterminer la lenteur du cisaillement de formations entourant un puits de forage dans la terre. Cette méthode comprend : la transmission de l'énergie sonique aux formations à partir d'une source de dipôle dans le puits de forage; la mesure des signaux des éléments d'onde orthogonaux qui ont traversés la formation à plusieurs endroits de réception dans le puits, endroits respectivement espacés à plusieurs distances du dispositif de transmission; la transformation des signaux dans le domaine de fréquences et la séparation des parties dispersives et non dispersives des signaux transformés; la détermination de la lenteur de cisaillement de la formation, lente et rapide, à partir des asymptotes de faible fréquence des parties dispersives des signaux transformés. On divulgue aussi des méthodes connexes pour déterminer la direction du cisaillement et l'ampleur de l'anisotropie des formations anisotropes entourant un puits de forage, et l'appareillage connexe.
Patent CA-2449961-A1 (CA)
Title: A catheter
Inventor: VALE DAVID
IPC: A61F2/95
Filed: 2002-06-27
Abstract: Published without an Abstract
Patent CA-2452354-A1 (CA)
Inventor: LEMAURE BERNARD
IPC: A23K20/195
Filed: 2002-06-28
Abstract: L'invention concerne une composition d'aliment pour animaux permettant de réguler le poids vif et de prévenir l'obésité et des troubles associés chez les animaux. Cette composition comprend, comme principe actif, au moins un végétal ou un extrait de végétal permettant de stimuler la dépense énergétique et/ou le brûlage des graisses. L'invention concerne également un procédé permettant d'améliorer la santé des animaux, notamment par prévention de l'obésité et de troubles métaboliques associés à l'obésité chez les animaux. L'invention concerne enfin un procédé permettant d'accroître la dépense énergétique, de réguler l'homéostasie du glucose et d'améliorer l'activité et la mobilité de l'animal.
Patent CA-2454365-A1 (CA)
Inventor: POOLE ROBERT N
IPC: B25B7/12
Filed: 2002-07-19
Abstract: L'invention concerne une pince étau réglable comprenant des moyens de serrage fixes présentant un manche et une mâchoire fixe opposée, une mâchoire coopérante montée pivotante sur les moyens de serrage fixes et un levier monté pivotant sur la mâchoire coopérante. Un guide est fixé à proximité du manche et un élément de verrouillage est disposé sur le guide aux fins de mouvement alternatif et de blocage. Au moins un élément de sollicitation fixé contraint l'élément de verrouillage en direction de la mâchoire fixe. Un bras est monté pivotant sur le levier et une cam est montée pivotante sur le bras et sur l'élément de verrouillage, de manière à pouvoir être déplacé entre un premier état permettant à l'élément de verrouillage d'effectuer un mouvement alternatif le long du guide et un second état prenant appui contre le guide et bloquant l'élément de verrouillage en prise par friction contre le guide.
Patent CA-2454684-A1 (CA)
Title: Eukaryotic cells and method for preserving cells
Inventor: OLIVIER ANN E
IPC: A61K35/36
Filed: 2002-08-05
Abstract: A dehydrated composition is provided that includes freeze-dried eukaryotic cells. The eukaryotic cells are loaded with an oligosaccharide (e.g., trehalose) which preserves biological properties during freeze-drying and rehydration. The oligosaccharide loading is conducted at a temperature of fr om greater than about 25~C to less than about 50~C, more preferably at about 35~C, with the loading solution having the oligosaccharide in an amount from about 10mM to about 100mM. These freeze-dried eukaryotic cells are rehydratable. A process for preserving and/or increasing the survival of dehydrated eukaryotic cells, including storing dehydrated eukaryotic cells having a residual water content greater than about 0.15 gram of water per gr am of dry weight eukaryotic cells.
Patent CA-2455145-A1 (CA)
Inventor: NIE GUIYING
IPC: C12N9/64
Filed: 2002-07-30
Abstract: The invention relates to a enzyme predicted to be a serine protease, which is specifically expressed in association with embryo implantation and placentation in pregnant uterus. The enzyme of the invention is useful in the evaluation of fertility and monitoring of early pregnancy, placental development and function, fetal development, parturition, and conditions such as pre-eclampsia, intrauterine growth restriction, early abortion, abnormal uterine bleeding, endometriosis, and cancers, and may provide a potential target for contraception. It may also be important in diseases of the heart, testis or ovary, and may play a role in muscle function, including cardiac muscle, skeletal muscle, lung and the diaphragm. In addition the enzyme of the invention is useful in the screening of candidate drugs for fertility control or for treatment of fertility-related disorders.
Patent CA-2456358-A1 (CA)
Title: Electro luminescent switch panel
Inventor: TONDRA AARON P
IPC: H01H9/16
Filed: 2004-01-27
Abstract: A floor care appliance such as a vacuum cleaner is provided having a display panel having at least one indicator light for indicating a status of a feature of the appliance wherein the indicator light is lighted by electro luminescent lighting. The electro luminescent fighting is also used on a control panel for a floor care appliance to backlight one or more switches used to control a feature or mode of the appliance wherein the backlighting indicates a status of the feature or mode associated with a particular switch. The switches and electro luminescent backlighting are embedded between layers of a thin film allowing the display and control panels to be mounted on a curved surface such as the handle of the floor care appliance.
Patent CA-2459531-A1 (CA)
Title: Heterocyclic substituted 2- (4-phenoxy) pyridine derivatives and related compounds as sodium channel blockers for the treatment of neuronal damage and neurodegenerative conditions
Inventor: GOEHRING R RICHARD
IPC: A61P25/28
Filed: 2002-09-06
Abstract: This invention relates to aryl substituted pyridines of Formula (I) or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein: Ar is selected from the group consisting of Ar1, Ar2, Ar3 and Ar4, wherein Ar1 is R1 is selected from the group consisting of an optionally substituted alkyl, amino, alkylthiol, C(O)R10, SO2R10, and OC(O)NH2; R2 is Ym-(CH2)n-Z, wherein Y is O, S or NR11, wherein R11 is hydrogen or alkyl, Z is a saturated heterocyclic ring optionally substituted at one or more carbon atoms, m is 0 or 1, and n is 0-6; or a pharmaceutically acceptable salt, prodrug or solvat e thereof, wherein Ar and R1-R4 are set in the specification. The invention is also directed to the use of compounds of Formula I for the treatment of neuronal damage following global and focal ischemia, for the treatment or prevention of neurodegenerative conditions such as amyothrophic lateral sclerosis (ALS), and for the treatment, prevention or amelioration of both acute or chronic pain, including diabetic neuropathy, as antitinnitus agents , as anticonvulsants, and as antimanic depressants, as local anesthetics, and as antiarrhythmics.
Patent CA-2460795-A1 (CA)
Title: Propylene oxide purification
Inventor: SAWYER GARY A
IPC: C07D303/04
Filed: 2002-08-26
Abstract: A mixture of propylene oxide and methanol is separated by liquid/liquid extraction using water and a hydrocarbon such as n-octane as extractive solvents.
Patent CA-2466541-A1 (CA)
Inventor: FUERSTENAU MAURICE C
IPC: C22B1/00
Filed: 2004-05-06
Abstract: A method for passivating sulfidic iron-containing rock comprising: contacting sulfidic iron-containing rock with a magnesium-containing substance, a manganese-containing substance, and a calcium-containing substance; and adjusting the pH of the system to below about 11, is provided. The method can be used to prevent acid rock drainage of metal-bearing rocks or to produce a pretreated ore or rock which can be contacted with a lixiviating agent to extract metals from the pretreated ore or rock.
Patent CA-2468443-A1 (CA)
Title: Nylon polymer blends and films made therefrom
Inventor: AKKAPEDDI MURALI K
IPC: C08L77/06
Filed: 2002-11-12
Abstract: This invention relates to blends of nylon homopolymers and copolymers with poly(hydroxyamino ether) polymers. More particularly, there are provided blends of nylon 6 and its copolymers with poly(hydroxyamino ether) which for m films having high miscibility, high clarity and good processability.
Patent CA-2469187-A1 (CA)
Inventor: KONG NORMAN
IPC: C07D233/26
Filed: 2002-12-09
Abstract: L'invention concerne des composés représentés par les formules I et II, ainsi que des sels et esters de ces composés, acceptables sur le plan pharmaceutique, détaillées dans la description, qui inhibent l'interaction de la protéine MDM2 avec un peptide de type p53 et qui possèdent une activité antiproliférative.
Patent CA-2470703-A1 (CA)
Title: Oral pharmaceutical products containing 17.beta.-estradiol-3-lower alkanoate, method of administering the same and process of preparation
Inventor: ALOBA OLUWOLE T
IPC: A61P25/28
Filed: 2002-12-20
Abstract: A pharmaceutical dosage unit for oral administration to a human female comprising a therapeutically effective amount of 17.beta.-estradiol-3-lower Alkanoate, most preferably 17.beta.-estradiol-3-acetate, and pharmaceutically acceptable carrier is disclosed. Also disclosed is a method for treating a human female in need of 17.beta.-estradiol and a contraceptive method by oral administration of the pharmaceutical dosage unit and a method of preparing a pharmaceutical composition that may be used to form the pharmaceutical dosage unit of the invention.
Patent CA-2470965-A1 (CA)
Title: System biology approach: high throughput screening (hts) platforms with multiple dimensions
Inventor: CHEN TAO
IPC: C12Q1/68
Filed: 2002-12-17
Abstract: This invention provides the systematic and oriented codon-based high- throughput methods for the identification of both known and unknown sequences. The identification are focused on the sequences of ORF of the gene and the corresponding transcriptional and translational products (RNA and peptide sequences) such as 5.prime.-end from the start codon, 3.prime.-end from the stop codon and two consecutive codon sequence which is recognized by a restriction enzyme between 5'-end and 3.prime.-end of a sequence. The present invention provides the relevant genetic algorithms for the sequence identification and library construction, such as 61.sup.(n-1) / 20.sup.(n-1), 61.sup.n / 20.sup.n, 61.sup.(n-2) / 20.sup.(n-2). It also provides the genetic algorithms of 64.sup.(n-1) and 64.sup.n to define 5'-UTR, 3'-UTR in order to deduce oligonucleotide sequences which span start codon and stop codon respectively. The present invention classified oligonucleotides in accordance with the G+C content to provide uniformed hybridization conditions. Applications include PCR, cloning, dot-blot hybridization, library construction, sequence determination, signature sequence and signature signal identification, ELISA, DNA and protein microarrays.
Patent CA-2474650-A1 (CA)
Title: Apparatus for preparing hot beverages, in particular soups
Inventor: FRANCOIS JEAN-JACQUES
IPC: A47J31/41
Filed: 2003-02-03
Abstract: An apparatus for preparing hot beverages, in particular soups, includes a frame (1) containing a heating system (2) for heating water drawn from a water main or, alternatively, from a tank, and for converting the water into pressurized steam. The steam is delivered to a heating chamber (3) having a discharge duct (4) that passes through the heating chamber. A beverage to be prepared is stored in an aseptic pack (61) placed in a removable receptacle (7) housed in the frame (1). The liquid beverage is delivered from the aseptic pack (61) to the discharge duct (4) by a sequential dispenser (6), and is then discharged to a container (5).
Patent CA-2476484-A1 (CA)
Title: A system for sale of consumer goods
Inventor: SCOTT NICHOLAS ARTHUR
IPC: G06Q30/00
Filed: 2003-02-21
Abstract: A system for the sale of consumer goods, wherein the system comprises a device for providing a customer with a non-validated token that represents an article of merchandise. The article is to be paid for by the customer at a checkout unit when the token is checked by said unit. Said checkout unit has a means for prividing a validated token that bears a transaction code. Said checkout unit has a means for communicating with an article dispensing device and providing the article dispensing device with said transaction code after the article has been paid for. The validated token is used to obtain the purchased article from the article dispensing device with the aid of a comparator device within the article dispensing device which compares the transaction code on the validated token with the transaction code communicated by said communication device, wherein the article dispensing device delivers the purchased article when there is a defined code correspondence.
Patent CA-2479695-A1 (CA)
Inventor: YAMAGUCHI JUN
IPC: G01N21/03
Filed: 2003-03-14
Abstract: A micro-chemical system-use chip able to be downsized with a measurement sensitivity enhanced, and a micro-chemical system. The micro-chemical system - use chip (1) comprises a platy glass substrate (10) that has a U-shaped flow path (11) thereinside. The flow path (11) consists of a lengthwise flow path (11a) and a pair of lateral flow paths (11b, 11c) connected to respective en ds of the lengthwise flow path (11a). The glass substrate (10) has two hollow spaces coaxially with the flow path (11a) in the vicinities of the opposite ends of the flow path (11a), and the two hollow spaces house refractive-inde x- profile-type rod lenses (14, 15) respectively. An optical fiber (16) that propagates a detection beam from a light source is connected to the rod lens (14), and an optical fiber (17) that guides the received detection beam to a measuring instrument to the rod lens (15).
Patent CA-2481714-A1 (CA)
Title: Far field source emulator for antenna calibration
Inventor: BARKER DELMAR L
IPC: H01Q3/26
Filed: 2002-08-22
Abstract: A radar antenna for a guided missile is calibrated in flight using a point source of microwave radiation and a lens to emulate a far field source. The microwave source and lens fit behind a metal cap at the leading end of the radome and so do not adversely affect the radar. A variety of techniques to power the point source are disclosed, and a variety of lens arrangements are disclosed. The invention allows a radar antenna to be calibrated in flight, and so insures against mis-calibration due to aging components as well as the heat and mechanical forces associated with storage and/or launch of the missile.
Patent CA-2487017-A1 (CA)
Inventor: RUPCIC RENATA
IPC: C07D235/02
Filed: 2003-05-20
Abstract: L'invention concerne des dérivés de classe de 1-thia-3-aza-dibenzoazulène représentés par la formule (I). L'invention concerne également des sels et des solvates de ces dérivés acceptables sur le plan pharmacologique, des procédés et des intermédiaires destinés à la préparation de ces dérivés ainsi que leurs effets anti-inflammatoires, notamment l'inhibition de production du facteur de nécrose tumorale .alpha. (TNF-.alpha.) et l'inhibition de production d'interleukine-1 (IL-1), ainsi que leur action analgésique.
Patent CA-2487055-A1 (CA)
Title: Utilisation d'un reseau telephonique public commute pour l'authentification et l'autorisation dans des transactions en ligne
Inventor: ROLFE ANDREW R
IPC: G06Q20/40
Filed: 2003-05-22
Abstract: L'invention concerne un système (10) d'authentification et/ou d'autorisation (38) qui incorpore deux canaux de communication (16, 17), et au moins un élément parmi des sources de données de tierce partie, des algorithmes de corrélation géographique, des algorithmes de reconnaissance vocale, des algorithmes de comparaison biométrique vocale, et des mécanismes permettant de convertir des données textuelles en paroles. L'identité d'un visiteur de site (V) peut être vérifiée à l'aide d'une ou de toutes ces caractéristiques combinées à une adresse de visiteur sur l'un des canaux (16, 17).
Patent CA-2488201-A1 (CA)
Title: Arthroscopic tissue scaffold delivery device
Inventor: MCRURY IAN D
IPC: A61B17/12
Filed: 2004-11-22
Abstract: A small diameter delivery device capable of delivering a tissue loaded scaffold arthroscopically to a tissue defect or injury site without reducing the pressure at the injury site is provided. The scaffold delivery device of the present invention comprises a plunger system that includes two main components: an insertion tube and an insertion rod. The insertion tube has a flared proximal end for holding a tissue scaffold prior to delivery. An elongate, hollow body extends from the flared proximal end to a distal end of the insertion tube, and defines a passageway that extends through the body for delivery of the tissue scaffold. The insertion rod has an elongate body that extends into a handle at a proximal end and a tip at a distal end. The insertion rod is configured to be removably disposed within the insertion tube for sliding along the passageway to effect delivery of the tissue scaffold through the insertion tube.
Patent CA-2488873-A1 (CA)
Inventor: INTOCCIA AL
IPC: A61F2/958
Filed: 2003-06-09
Abstract: A method for removing an object from a body includes dispensing fluid into t he body lumen, and causing the dispensed fluid to propel the object along the body lumen. A device for removing an object from a body lumen includes a flu id dispenser for dispensing fluid into the body lumen, and a pump in fluid communication with the dispenser.
Patent CA-2489327-A1 (CA)
Inventor: PARKER JOHN M
IPC: B21D39/00
Filed: 2003-03-20
Abstract: A self-attaching nut having an annular pilot (24), an annular flange (30) surrounding the pilot and an annular groove (34) in the bearing surface surrounding the pilot, wherein the bottom wall (36) of the groove has inclin ed rectangular protuberances (42) and the outer wall (40) of the groove has radial channel-shaped grooves (48) spaced between the radial protuberances. During installation, panel metal is driven against the inclined radial protuberances, driving panel metal under the inclined outer wall of the roov e and into the radial grooves in the flange.
Patent CA-2492201-A1 (CA)
Inventor: RUETTIMANN AUGUST
IPC: C07B61/00
Filed: 2003-07-14
Abstract: L'invention concerne un procédé de fabrication d'un isoflavone hydroxylé de formule (I). Ledit procédé consiste à faire réagir 2-hydroxydeoxybenzoïne substitué de façon appropriée de formule (II) avec un anhydride d'acide formique de formule HCOOCOR?3¿, dans laquelle R?3¿ représente C¿2-20?-alkyle ou d'autres groupes divers en présence d'une base ou dans un solvant qui agit comme une base, et si nécessaire à promouvoir l'hydrolyse consécutive de la forme acylée ainsi produite de l'isoflavone hydroxylée de formule I par acidification. 5,7-dihydroxyisoflavones, par exemple, génistéine (5,7,4'-trihydroxyisoflavone) sont des produits de ce processus ayant un intérêt particulier. Les isoflavones présentent plusieurs effets biochimiques utiles.
Patent CA-2493461-A1 (CA)
Title: Drug discovery method
Inventor: OFER DROR
IPC: C12Q1/68
Filed: 2002-07-24
Abstract: A method of obtaining information about a chemically active area of a target molecule, for example for drug discovery, comprising: providing a set of substantially rigid chemical gauges; reacting said target with a plurality of gauges of said set of gauges; assaying a binding of said gauges with said target to obtain a plurality of assay results; and analyzing said assay results to obtain information about said chemically active area.
Patent CA-2493913-A1 (CA)
Title: Ppar alpha selective compounds for the treatment of dyslipidemia and other lipid disorders
Inventor: SAHOO SOUMYA
IPC: A61P25/00
Filed: 2003-07-25
Abstract: A class of chromane and chromene compounds having the structure shown below and pharmaceutically acceptable salts thereof are useful as therapeutic compounds, particularly in the treatment and control of hyperlipidemia, hypercholesterolemia, dyslipidemia, and other lipid disorders, and in delayi ng the onset of or reducing the risk of conditions and sequelae that are associated with these diseases, such as atherosclerosis.