baber/WOPTO huggingface dataset:
Patent EP-2960341-B1 (EP)
Inventor: JACKSON DAVID B
IPC: G01N33/74
Filed: 2008-11-28
Granted: 2018-06-27
Abstract: There is disclosed a molecular composition(s) of a novel tissue protective erythropoietin (EPO) binding receptor protein complex, termed NEPOR. Presence of NEPOR components on a tumour allows EPO to impinge on the survival of associated cells thereby enhancing tumour progression and negatively effecting patient survival. There is disclosed that presence of NEPOR represents a prognostic biomarker for poorer patient outcome. Thus, the method disclosed is for stratifying patients having a tumour as suitable (i.e. NEPOR not present) or non-suitable (i.e., NEPOR present) for EPO treatment, comprising: (a) isolating a tissue sample from an individual who is receiving or is a candidate for receiving erythropoietin, (b) determining the level of expression of the NEPOR gene(s) (mRNA) and/or the presence of the NEPOR gene product (protein) from the isolated tissue, and (c) correlating the presence of an NEPOR gene expression product or the presence of NEPOR protein to a physiological response to the treatment with erythropoietin. Furthermore, by disclosing the molecular compositions of NEPOR species, there are disclosed methods for rationally identifying/designing NEPOR modulating therapeutics. Thus, the present disclosure provides methods for treating neurological insults such as stroke (via enhancement of NEPOR activity) and cancer (via down-regulation of cyto-protective signaling from NEPOR).
Patent EP-0012603-B1 (EP)
Title: Method and apparatus for tracking an optically readable information track
IPC: G11B7/08
Filed: 1979-12-12
Granted: 1984-04-04
Abstract: pparatus. anc a related method formaintaining an incl. dent beam of radiation (19) in alignment wan the centerlne of a movable optically readable information track (13) wherein the track comprises a succession of light-reflecting (15) and light-scattering (17) regions representative of a frequency modulated carrier and the sides of the track are adapted to scatter incident radiation in predetermined directions. The apparatus includes photodetector means (41,43) for sensing the amount of radiation scattered by each side of the track and for generating an error signal (71) indicative of the deviation of the incident beam relative to the centerline (51) of the track, along with means (37) responsive to the error signal for controllably moving the incident beam into alignment with the centerline of the track
Patent EP-0023547-B1 (EP)
IPC: B24B9/00
Filed: 1980-06-12
Granted: 1983-07-27
Abstract: A method and a device for the automatic removal of burrs or fins from workpieces such as castings by a grinding process. A feed for moving the workpiece perpendicular to the grinding wheel radius is provided for grinding along the length of the burr. A second constant velocity feed of reversible and alternating direction is provided for moving the grinding wheel radially into the workpiece. The load or circumferential torque on the grinding wheel is monitored to detect the abrupt increase in torque occurring when the grinding wheel has cut through the burr and encounters the body of the workpiece, whereupon the direction of the radial feed is reversed so that the grinding process follows the contour of the workpiece.
Patent EP-0031879-B1 (EP)
IPC: G21F9/16
Filed: 1980-10-28
Granted: 1984-03-28
Abstract: 1. Device for immobilizing in concrete radioactive wastes in waste drums, with the ingredients of the mixture being filled into the drum and concrete being produced directly after mixing of those ingredients in that drum ; with a shielded and alpha-tight cell to which the feed opening of the empty drum can be connected by means of an opening in the cell floor, which opening can be closed by means of a double lid, which can be swung out of the way ; with a hollow shielding cylinder extending into the cell from the top, the interior of which accommodates the mixing tools after their withdrawal from the drum, and from which they can be lowered into the drum for mixing and lifted back into the cylinder, respectively ; with a shielding plate (6) installed in the cylinder (2) in a vertical sliding bearing so that its top is sealed relative to the cylinder (2), which plate holds the driving mechanism (8, 9) for the mixing tools (3) ; with another driving mechanism (10) attached to the plate (6), by means of which a central section (7) turning in the plate (6) and accommodating the bearing fixture of the mixing tools can be turned around its center axis (17) ; with the guide ring (22) constituing the upper extension and bearing fixture of the plate (6) holding one end (30) of a bellows (13) around the driving mechanism, the other end (31) of which bellows is indirectly connected to the wall of the cell (1) and to the base plate (34), respectively, supporting the cylinder (2), the bellows (13) being attached to the upper inner rim (32) of a hollow sheet metal cap (33) open at the top and resting on the base plate (34) ; and with lifting elements (11) for lowering and lifting, respectively, the plate (6) holding the mixing tools (3), wich are located above that plate, i.e., outside the shielding opposite the contaminated interior (27) of the cell (1).
Patent EP-0018188-B1 (EP)
IPC: A24D3/02
Filed: 1980-04-14
Granted: 1983-05-04
Abstract: A tobacco smoke filter plug comprises fiber tow fillings in the form of cylinder, composed of an inner core phase and an outer skin layer different from each other in fibrous arrangement structure thereof, the inner core phase consisting of fillings in a folded arrangement structure having a folding axis forming an angle of  alpha  with respect to the central longitudinal axis of the filter plug in cross section, and the outer skin layer consisting of fillings in a folded structure substantially parallel to the central longitudinal axis of the filter plug in cross section and surrounding said inner core phase.
Patent EP-0027051-B1 (EP)
IPC: C25D17/10
Filed: 1980-10-07
Granted: 1984-07-11
Abstract: An electrode for use in electrolytic processes comprises a substrate of film-forming metal such as titanium having a porous electrocatalytic coating comprising at least one platinum-group metal and/or oxide thereof possibly mixed with other metal oxides in an amount of at least about 2 g/m<2> of the platinum-group metal(s) per projected surface area of the substrate. Below the coating is a preformed barrier layer constituted by a surface oxide film grown up from the substrate. This preformed barrier layer has rhodium and/or iridium as metal or compound incorporated in the surface oxide film during formation thereof in an amount of up to 1 g/m<2> (as metal) per projected surface area of the substrate.
Patent EP-0034756-B1 (EP)
IPC: G11B23/02
Filed: 1981-02-11
Granted: 1984-05-23
Abstract: A container for tape-like material wound into a roll or stored in a cartridge, which container consists of a bottom and a top part, which are pivotable relative to one another for the purpose of opening and closing the container and can, when the container is open, be telescoped with the aid of guides on the container, one of the parts possessing means for accommodating the roll or cartridge.
Patent EP-0051263-B1 (EP)
IPC: B23B29/04
Filed: 1981-10-28
Granted: 1986-01-15
Abstract: A quick-change tool holder for a lathe including a tool carriage, the holder comprising a support member adapted to be mounted on the tool carriage, a tool holder member adjacent the support member and including a first bore extending generally perpendicularly from the support member, and a second bore extending at about a right angle from the first bore. The holder also includes a mechanism for attaching the tool holder member to the support member, which mechanism comprises a mounting member which is detachably mounted on the support member, which is received in the first bore in the tool holder member, and which includes a bore. The attaching mechanism also includes a bolt which is received in the second bore, and which is movable between an operating position, wherein the bolt penetrates the bore in the mounting member and secures the mounting member in the first bore in the tool holder member, and a nonoperating position, wherein the bolt is withdrawn from the bore in the mounting member so that the tool holder member is detached from the mounting member.
Patent EP-0045554-B1 (EP)
IPC: G01N33/00
Filed: 1981-07-31
Granted: 1985-04-03
Abstract: Apparatus for measuring one or more polluting components in a certain atmosphere, consisting of a carrier gas supply system (1, 2, 3, 4, 5, 6, 7), a sample cock (8) for the supply of a certain amount of gas to be examined together with a carrier gas, an oven (11) containing a separating means for the components of the gas to be examined, a detector (12), an eliminator (13) for eliminating components which are not to be determined, and an integrator or peak height measuring system (14) for indicating the concentration of the component(s) which have been determined.
Patent EP-0055653-B1 (EP)
IPC: F02M59/36
Filed: 1981-12-15
Granted: 1985-05-22
Abstract: A pump including a hydraulically balanced distributor head (76) housing a pair of opposed plungers (74) actuated by an annular cam (82) and rotatably driven by a shaft (16) in synchronisation with the operation of an engine. The face type distributor head (76) has an outlet part (108) formed in an insert (102) sequentially interconnecting the pumping chamber (84) of the injection pump (14) to a plurality of injection parts (26,30 etc.) symmetrically disposed along the circumference of a circle concentric with the shaft (16) on the internal face of a distributor block (24) enclosing one end of a housing (10).
Patent EP-0051634-B1 (EP)
IPC: C22C32/00
Filed: 1981-04-20
Granted: 1986-08-20
Abstract: Precision molded articles, such as die cavities, pertaining to the field of powder metallurgy, and having high hardness and impact resistance, are made by combining granules of refractory and granules of a first metal or alloy which has a homogeneous crystalline appearance at a temperature below its melting point and a lower Rockwell Hardness than the refractory, mixing the granules with organic binder, molding the granule-binder mixture into a green molded preform, thermally degrading and removing the binder to form a skeletal preform, and infiltrating the preform with a second metal or alloy which will wet the first metal or alloy and has a lower Rockwell Hardness than the first metal or alloy, thereby forming a molded article having refractory granules fully enveloped within a single skeleton of the first metal or alloy, the refractory granules and skeleton being surrounded by layers or matrices of softer metals.
Patent EP-0053129-B1 (EP)
Title: Appareil a couper la vegetation
IPC: A01D34/416
Filed: 1981-04-27
Granted: 1986-08-06
Abstract: Appareil (11) a couper la vegetation avec une tete rotative (19) portant un fil ou ligne de coupe non metallique (21) s'etendant dans un plan de coupe. Une ligne de coupe supplementaire s'etend depuis une bobine d'alimentation (39) se trouvant dans la tete dans le plan de coupe sans action independante de l'operateur. Un mecanisme dans la tete assure une alimentation automatique de la ligne de remplacement lorsque l'extremite libre de la ligne de coupe est reduite a une longueur inferieure a une longueur maximum predeterminee dans le plan de coupe. La longueur de la ligne de coupe est toujours egale a cette longueur maximum predeterminee a toutes les vitesses de rotation, sans ajustement, et dans un mode pas-a positif d'avance de la ligne par segment. Le mecanisme d'alimentation de ligne possede une came d'echappement (56) avec un montage pivotant decentre (46) qui detecte a la fois les forces centrifuges sur la ligne de coupe et les changements de la vitesse de rotation de la tete.
Patent EP-0067165-B1 (EP)
IPC: C30B31/00
Filed: 1981-10-28
Granted: 1989-03-29
Abstract: A method for uniformly and reproducibly boron doping closely spaced silicon wafers (10-12) in a chamber (14) in a single batch by: first, forming a protective layer of silicon dioxide on the wafers by reaction with an oxidant gas; second, depositing boron on the wafers by introducing gaseous BCl<u3>u and H<u2>uO at a low flow rate and pressure (less than 10 torr for superior results which forms B<u2>uO<u3>u; and thirdly, heating the wafers in a non-oxidizing atmosphere to achieve redistribution of the boron in the wafers.
Patent EP-0066859-B1 (EP)
Title: Cathodically depositable aqueous dipping varnish composition
IPC: C25D13/06
Filed: 1982-06-04
Granted: 1984-10-10
Abstract: The invention relates to a cathodically depositable aqueous electro-dip lacquer coating composition containing as synthetic resin binder (A) from 50 to 99% by weight, based on the total quantity of synthetic resin binder, of one or more amino-1,2-epoxy resins, the amino-1,2-epoxy resin or-where several amino-1,2-epoxy resins are present-the mixture of amino-1,2-epoxy resins (a) having an average molecular weight (Mn) of from 700 to 10,000, (b) containing per 1000 molecular weight units from 0.2 to 3.6 lateral or terminal ethylenic double bonds corresponding to a hydrogenation iodine number of from 5 to 90, (c) containing primary and/or secondary alcoholic hydroxyl groups corresponding to a hydroxyl number of from 30 to 450 and (d) having an amine number of from 30 to 150, (B) from 1 to 50% by weight of a substantially non-acid polyester of a polycarboxylic acid containing at least two terminal or lateral, saturated and/or unsaturated  beta -hydroxy ester groups per molecule and having an average molecular weight of from about 1500 to 10,000, and (C) soluble and/or insoluble transesterification catalysts for the thermal crosslinking of (A) and (B) at temperatures above 140 DEG  C. The invention also relates to the use of the coating composition for cathodic deposition from a lacquer bath onto electrically conductive surfaces.
Patent EP-0075682-B1 (EP)
IPC: C09D5/08
Filed: 1982-08-06
Granted: 1985-05-15
Abstract: 1. Coating material for corrosion protection purposes based on aqueous emulsions and/or dispersions and/or solutions of film-forming binding agents into which pigments are stirred, characterised by an inorganic pigment mixture of transparent-acting compounds increasing the speed of drying and of transparent-acting compounds bringing about the corrosion protection in which the pigments, before introduction into the binding agent, are provided with an organic covering.
Patent EP-0078696-B1 (EP)
IPC: G11B23/087
Filed: 1982-11-01
Granted: 1987-03-04
Abstract: A tape cassette having a swingable cover adapted to cover and protect a tape stretched along the front side of the tape cassette, a cover locking member adapted to prevent swinging of the swingable cover by rotating in the thicknesswise direction of the tape cassette within a groove which is defined between the inner surface of one side wall of the swingable cover and the side wall of the box-like structure of the tape cassette and also between two side walls of the box-like structure which are on the extensions of the one side wall of the swingable cover and the above-mentioned side wall of the box-like structure. The groove serves also as a mis-insertion preventing groove for preventing the tape cassette from being inserted into the cassette holder in a wrong posture. According to this arrangement, it is possible to realize a compact construction while fulfilling all of the requisites for the tape cassettes.
Patent EP-0059655-B1 (EP)
Title: Process for the preparation of epsilon-caprolactam
IPC: C07C409/24
Filed: 1982-02-09
Granted: 1985-07-24
Abstract: This invention relates to a process for the preparation of stable solutions of  epsilon -caprolactone by means of the oxidation of cyclohexanone by a percarboxylic acid containing 2 to 4 carbon atoms. According to the invention, the percarboxylic acid is in the form of a crude solution, such as that resulting from the reaction of hydrogen peroxide with the corresponding carboxylic acid in the presence of a boric acid catalyst with the continuous elimination of water by azeotropic entrainment.
Patent EP-0086826-B1 (EP)
Title: Alpha-branched alkylthiophosphate pesticides
IPC: A01N57/12
Filed: 1982-08-13
Granted: 1986-01-22
Abstract: Novel compounds of the formula <IMAGE> in which R is an  alpha -branched alkyl group of 4 to 8 carbon atoms or cycloalkyl group of 5 to 8 carbon atoms having excellent residual activity when soil incorporated for control of soil borne insects and nematodes.
Patent EP-0100883-B1 (EP)
IPC: D06B19/00
Filed: 1983-07-08
Granted: 1989-03-15
Abstract: 1. An apparatus for supplying and applying foamed scouring solutions on a cloth web (1) or the like wherein a tank (10) is provided which extends over the working width, receives the supplied foam, has an exit cross-section and has at least in one side zone an end limit so arranged that its position is movable in the tank, characterised in that the tank is a receiving tube (10), at least one end boundary of which is in the form of a sealing boundary disc (4) which receives sealingly and movingly a displacement member (13) extending axially through the tube (10).
Patent EP-0102590-B1 (EP)
IPC: C04B35/58
Filed: 1983-08-24
Granted: 1986-12-10
Abstract: The present invention is concerned with a ceramic formed body comprising a ceramic matrix and at least one phase of ceramic incorporation material dispersed therein, characterized by a dense, microcrack-free ceramic base matrix and compressive zones incorporated therein which consist of a mixture of the base matrix material with unstabilized zirconium dioxide particles which are predominantly monoclinic at ambient temperature. The present invention is also concerned with a process for the production of such ceramic formed bodies and with the use thereof as constructional elements in the hot region of heat engines.
Patent EP-0122973-B1 (EP)
IPC: F16K11/10
Filed: 1983-12-20
Granted: 1987-06-24
Abstract: 1. Mixing valve, with a housing (1) comprising a water inlet connection (18), a cold water connection (17) and a mixed water outlet connection (19), with a device for preadjusting the quantity of water flowing into a mixing chamber, and with a flow control valve (21) for adjusting the quantity of water flowing out through the mixed water outlet connection (19), a quantity adjustment shank (2) of the flow control valve and a temperature adjustment sleeve (3) being taken coaxially out of the housing (1), and the temperature adjustment sleeve (3) is provided with a control disc (6) which has two facial kidney-shaped control apertures (8, 9) and with which it rests on two water inlet ports (10, 11), characterised in that the quantity adjustment shank (2) and the temperature adjustment sleeve (3) extend out of the housing (1) with clearance therefrom and with clearance from one another which obviates bearing against each other.
Patent EP-0112548-B1 (EP)
IPC: C01B6/04
Filed: 1983-12-20
Granted: 1989-09-13
Abstract: A method of preparing an active magnesium-hydride or magnesium hydrogen-storer system which can reversibly take up H2, comprising contacting finely divided magnesium hydride or metallic magnesium with a solution of a metal complex or of a metal-organic compound of a transition metal of Subgroups IV-VIII of the periodic table, and then removing the solution. The product performs better with regard to speed and efficiency upon repeated hydrogenation and dehydrogenation, as in hydrogen storage and evolution.
Patent EP-0122385-B1 (EP)
IPC: G02B7/24
Filed: 1984-02-11
Granted: 1987-01-07
Abstract: A microscope tube having several sections articulated with respect to each other. A first stationary section (1) is hinged to a second section (2) which can swing upwardly and downwardly, and this is hinged to a third section (3) which hangs downwardly from the second section, the free lower end of the third section being swingable horizontally toward and away from the observer or user of the microscope. The third section has a fourth section (4) hinged to it to tilt on a horizontal axis, and this fourth section carries the eyepiece of the microscope. With this arrangement, the eyepiece may be adjusted to various positions vertically and horizontally to suit the comfort of the observer, and may be tilted to various viewing angles quite independently of its vertical or horizontal position. Mirrors within the tube at the hinge joints direct the optical beam properly from one section into the next section, and these mirrors turn through half the angle of swing when one section swings relative to the next. An additional optical system within the tube forms an intermediate image, and the observer sees the object in proper erect position in proper side-to-side relationship, rather than reversed. Provision is made for attachment of a camera or other desired auxiliary apparatus.
Patent EP-0119627-B1 (EP)
IPC: H03C1/00
Filed: 1984-03-19
Granted: 1990-05-30
Abstract: 1. Modulator circuit realized as a switched capacitor (SC) filter, which is driven by a modulation clock (vphi M , ~v~p~h~i M ), comprising switches, capacitors and at least one operational amplifier (3) whose non-inverting input (5) is connected to a reference potential (1'), and in which an SC integrator driven by two different clock phases (vphi, ~v~p~h~i) is formed with the operational amplifier (3), and in which there is furthermore upstream of the inverting input (5) of the operational amplifier (3) an SC network which consists of a capacitor (6) which is charged during the integrator or network clock phase (vphi), and which delivers its charge during the modulation clock phases (vphi M or ~v~p~h~i M ) with opposite signs to the integration capacitor (7) associated with the operational amplifier (3), characterized in that the capacitor (6) to be charged during the integrator or network clock phase (vphi) is connected downstream of the input terminal (1, 1'), with intermediate connection of series arm and shunt arm switches (13, 14), in that following this capacitor (6) is a switch network (15, 16, 17, 18) which delivers the network clock phases (vphi and ~v~p~h~i) in an alternating manner in the rhythm of the modulation clock (vphi M and ~v~p~h~i M ) to a shunt arm switch (9) and series arm switch (10) respectively, and in that the series arm switch (10) is connected to the inverting input of the operational amplifier, in that provided in the filter output is a switch (11) which is followed by the output terminals (2, 1'), and in that the integration capacitor (7) and an attenuation capacitor (8) are switched between the output (23) and the inverting input (5) of the operational amplifier (3).
Patent EP-0150289-B1 (EP)
IPC: C10B41/00
Filed: 1984-11-12
Granted: 1987-05-06
Abstract: At a coke oven of a coking plant, each operating machine is provided with a U-shaped detector unit equipped with infrared light gates. Each operating station of the coke oven is provided with a signal plate carrying positioning marker elements for fine tuning the positioning of the operating machine at the operating station and with identification marker elements for identifying the respective operating stations. Each infrared light gate includes an infrared light source and an infrared light sensor connected to an electronic evaluation circuit comprising a memory with a reading monitor for detecting and correlating the coded identification markers on the signal plates. The electronic evaluation circuit also includes an electronic position evaluation subcircuit which controls the drive of the respective coke oven operating machine to move the same at a reduced speed if a first positioning pulse is transmitted and to stop the operating machine upon the occurrence of a pair of positioning pulses as well as an identification signal identifying a desired operating station.