baber/WOPTO huggingface dataset:
Patent WO-2019000042-A1 (WO)
Title: Liquid-liquid mixing device suitable for sample preparation by liquid-liquid extraction
Inventor: SHELLIE ROBERT
IPC: B01D11/04
Filed: 2018-06-28
Abstract: A liquid-liquid mixing device (10, 210) includes a barrel (20, 220) with a liquid port (23) at or adjacent one end. A plunger assembly (30) is reciprocably moveable along an axis in the barrel (20, 220) and includes a seal member (31, 231) and an agitator (50, 250). The seal member (31, 231) is in sealingly slidable engagement with the internal wall of the barrel (20, 220) to define a variable volume chamber (24, 224) therein in communication with the liquid port. The agitator (50, 250) is reciprocably moveable in the variable volume chamber (24, 224), which agitator (50, 250) includes one or more end to end passages (54) through which liquid in the chamber (24, 224) is forced as the agitator (250) reciprocates in the chamber (24, 224). The device (10) also includes a mode selector mechanism (60, 28, 46, 64, 65, 90, 92, 94, 96) for selection between at least two modes of operation for the plunger assembly, wherein the mode selector mechanism (60, 28, 46, 64, 65, 90, 92, 94, 96) is adjustable between two or more modes whereby movement of the plunger assembly (30) effects either movement of the agitator (50, 250) with the seal member (31, 231) or movement of the agitator (50, 250) relative to the seal member (31, 231), depending on the selected mode.
Patent AU-2018203493-A1 (AU)
Title: Breathing tube assemblies with adjustable elbow
Inventor: MILLER JEREMY LIVINGSTON
IPC: A61M16/16
Filed: 2018-05-17
Abstract: Breathing tube assemblies for use with a respiratory therapy device, such as a continuous positive airway pressure (CPAP) device, includes an elbow that permits adjustment of a position of the breathing tube assembly relative to the respiratory therapy device. In some arrangements, the breathing tube assembly includes a breathing tube and a swivel elbow. The breathing tube is rotationally fixed relative to the respiratory therapy device and the swivel elbow rotatable relative to the breathing tube. In other arrangements, the breathing tube assembly includes an elbow that can be coupled to the respiratory therapy device in one of several possible positions. -32- N4t 'I-
Patent AU-2018203515-A1 (AU)
Title: Targeted genome editing in zygotes of domestic large animals
Inventor: TELUGU BHANU PRAKASH V L
IPC: C12N15/85
Filed: 2018-05-18
Abstract: C:\Interwoven\NRPortbl\DCC\AAR\16989406 _.docx-17/052018 A method is provided of targeted genome editing of an animal using site specific homologous integration. A composition comprising a single stranded oligonucleotide or double stranded nucleic acid molecule comprising a nucleic acid molecule of interest and sequences flanking a target locus cleavage site is injected into the zygote of an animal along with a nuclease and a guide nucleic acid molecule that targets the nuclease to a target locus. The composition is injected into the zygote after fertilization and prior to formation of a nucleus. The nucleic acid molecule of interest is recombined into the genome with high efficiency. The process allows for integration of nucleic acid molecules into the genome of animals in which the pronuclei cannot be visually observed during injection.
Patent AU-2018204390-A1 (AU)
Title: Axial piston pump
Inventor: KRONPASS MANUEL
IPC: F04B1/20
Filed: 2018-06-19
Abstract: The invention relates to an axial piston pump, particularly for hydraulic systems, comprising a cylinder drum (1) which can be rotationally driven about an axis (15) in a 5 pump housing (7), and in which piston cylinder units are arranged in a circle at an offset, said pistons (21) being at least indirectly supported on a swashplate (3) by their actuation end (31) which is accessible outside the cylinder drum (1). Between the swept volumes (19) of the piston cylinder units and a stationary fluid inlet and stationary fluid outlet of the pump housing (7), a control device (23) is arranged which comprises fluid 10 channels (25, 26) for the targeted transfer of fluid from the fluid inlet into the swept volumes (19) and from said swept volumes (19) to the fluid outlet. The invention is characterised in that at least one pressure compensation channel (28, 30) is provided in the control device (23), between said fluid channels (25, 26), in order to build or release fluid pressure in the swept volumes (19) in a targeted manner.
Patent AU-2018208848-A1 (AU)
Title: Heterocyclic spiro compounds as MAGL inhibitors
Inventor: BRODNEY MICHAEL AARON
IPC: A61P3/00
Filed: 2018-01-09
Abstract: The present invention provides, in part, heterocyclic spiro compounds of Formula I: and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating MAGL-mediated diseases and disorders including, e.g., pain, an inflammatory disorder, depression, anxiety, Alzheimer's disease, a metabolic disorder, stroke, or cancer.
Patent AU-2018211274-A1 (AU)
Title: Refrigeration cycle apparatus and refrigeration cycle system
Inventor: SUZUKI YASUHIRO
IPC: F25B49/02
Filed: 2018-08-02
Abstract: Provided is a refrigeration cycle apparatus including: a refrigeration cycle configured to circulate refrigerant; a heat exchanger unit configured to accommodate at least a heat exchanger of the refrigeration cycle; and a controller 5 configured to control the heat exchanger unit, in which: the heat exchanger unit includes: an air-blowing fan; and a refrigerant detection unit configured to detect a concentration of leaked refrigerant and to output a detection signal to the controller; and the controller is configured to operate the air-blowing fan when detecting leakage of the refrigerant, and to stop the air-blowing fan triggered by becoming 10 positive from negative of a temporal change of the concentration of the leaked refrigerant.
Patent AU-2018220061-A1 (AU)
Title: Methods of construction and components therefor
Inventor: WHEELER RUSSELL
IPC: E04C2/00
Filed: 2018-08-22
Abstract: A shrinkage facilitator including a conduit adapted to receive therein an elongate starter bar; positioning means in said conduit or connected to said conduit for positioning a starter bar in a predetermined first position in said conduit, said positioning means being adapted to allow relative lateral movement of a starter bar positioned in said conduit from said first position to a second position upon a predetermined force being applied to said conduit or the starter bar.
Patent AU-2018229722-A1 (AU)
Title: Inhibitors of beta secretase
Inventor: VOS ANN MARLEEN
IPC: C07D513/04
Filed: 2018-03-06
Abstract: The present invention relates to tricyclic inhibitors of beta-secretase having the structure shown in Formula (I) and (II) (I) and (II) and the tautomers and the stereoisomeric forms thereof, wherein the radicals are as defined in the specification. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which beta-secretase is involved, such as Alzheimer's disease (AD), mild cognitive impairment, senility, dementia, dementia with Lewy bodies, Down's syndrome, dementia associated with stroke, dementia associated with Parkinson's disease, dementia associated with beta-amyloid, age-related macular degeneration, type 2 diabetes and other metabolic disorders.
Patent AU-2018246214-A1 (AU)
Title: Niraparib compositions
Inventor: WU GEORGE
IPC: A61K31/454
Filed: 2018-03-27
Abstract: The present invention relates to compositions comprising the compound niraparib, in particular certain solid forms of niraparib.
Patent AU-2018247938-A1 (AU)
Title: An implantable medical device
Inventor: O'HALLORAN MARTIN
IPC: A61B18/14
Filed: 2018-04-05
Abstract: 1. A device for occlusion of a body lumen comprises an implantable occlusion apparatus (3) operably attached to an elongated catheter member (4) configured for transluminal delivery and deployment of the occlusion apparatus in the body lumen. The occlusion apparatus comprises a radially expansible element (5) detachably attached to the elongated catheter member, and adjustable between a contracted orientation suitable for 10 transluminal delivery and a deployed orientation configured to occlude the body lumen, an energy delivery element (6, 14, 21) configured to deliver energy to surrounding tissue to heat the tissue, and a sensor (7) configured to detect a parameter of the wall of the body lumen. The energy delivery element (6, 14, 21) and sensor (7) are axially movable independently of the radially expansible element whereby, in use, the energy delivery 15 element and sensor can be transluminally retracted leaving the radially expansible element in-situ occluding the body lumen.
Patent AU-2018250454-A1 (AU)
Title: Wind power generation apparatus, tower and method for suppressing tower shadow effect of tower
Inventor: MA SHENGJUN
IPC: F03D13/20
Filed: 2018-03-19
Abstract: A wind power generation apparatus, a tower and a method for suppressing a tower shadow effect of the tower. The tower is provided with suction through holes extending through a circumferential wall thereof, and the suction through holes are distributed in a 5 circumferential direction of the tower; the tower is further provided with a suction apparatus, and the suction apparatus can perform suction to the suction through holes from outside to inside. With the tower and the method, when the suction through holes at a windward side are suctioned, the adverse influence of the tower shadow effect can be weakened or eliminated, a service life of a pitch varying bearing can be prolonged, a noise can be reduced 10 and a wind energy utilization coefficient can be improved. When the suction through holes at a position of a bypassing flow detachment are suctioned, vortex-induced vibrations can also be suppressed. In addition, suction intensity may be adjusted at any time during suction according to practical situations, which has higher flexibility. When the suctioned airflow is discharged to the inside of the tower, functions of cooling by heat exchange, blocking the 15 outside rainwater, sand, dust and the like from entering a flow guiding hood or a hub can also be performed.
Patent AU-2018251878-A1 (AU)
Title: Shroud assembly
Inventor: SESSA MICHAEL JOSEPH
IPC: E21B17/046
Filed: 2018-04-12
Abstract: A shroud assembly (100) having two semi-cylindrical covers (111,112) having a connector (125) at each end; a plurality of receiver rings (122) for supporting the covers and engaging the connector; and an extender ring (150) configured to move a first receiver ring toward a second receiver ring.
Patent AU-2018253473-A1 (AU)
Title: A Method of Determining a Bet Amount and a Gaming System
Inventor: ROACH NICK GRAHAM
IPC: A63F13/00
Filed: 2018-10-23
Abstract: A method of determining a bet amount in a gaming system comprises determining a number of play combinations to be played by a player, receiving a total bet amount from the player, and determining a bet per play combination amount from the determined number of play combinations and the received total bet amount.
Patent AU-2018254700-A1 (AU)
Title: Control system for an automatic sliding door
Inventor: DREYER ROGER
IPC: E05F15/73
Filed: 2018-04-16
Abstract: A control system for a sliding door operator system (1) having at least one sliding wing (12, 14) and a door header (16) is provided. The control system comprises a first sensor (20a) configured to define a first activation zone (A1), a first wing presence zone (W1) and a first side presence zone (S1). The system further comprises a controller (30) configured to evaluate data from the first sensor (20a) for controlling the operation of the at least one sliding wing (12, 14) in the sliding door operator system (1).
Patent AU-2018256512-A1 (AU)
Title: Devices and methods facilitating sleeve gastrectomy procedures
Inventor: TRIVEDI AMIT
IPC: A61B17/32
Filed: 2018-10-30
Abstract: DEVICES AND METHODS FACILITATING SLEEVE GASTRECTOMY A device for use in bariatric surgery includes a tube member, a coupling member, and a rod member. The tube member includes a proximal portion and a distal portion having a distal end. The coupling member is affixed to the tube member. The rod member includes a proximal portion and a distal portion having a distal end. The rod member is slidably coupled with the coupling member. The distal end of the rod member is fixedly coupled to the distal end of the tube member. The proximal portion of the rod member is translatable relative to the tube member to transition the distal portion of the rod member between a contracted position, wherein the distal portion of the rod member extends along the distal portion of the tube member, and a deployed position, wherein the distal portion of the rod member bows outwardly relative to the tube member.
Patent AU-2018258223-A1 (AU)
Title: Adaptive trigger for a microcurrent stimulation device
Inventor: CLAUDE JOHN
IPC: A61B5/053
Filed: 2018-04-24
Abstract: A microcurrent treatment device includes an adaptive trigger circuit configured to dynamically determine a triggering threshold for applying a therapeutic microcurrent via a treatment electrode to a nerve node on a persons face for treatment of a sinus condition.
Patent AU-2018263520-A1 (AU)
Title: An expelling device and a milking arrangement provided with such a device
Inventor: HAMERTON LANCE
IPC: A01K15/02
Filed: 2018-04-27
Abstract: An expelling device, configured to incite an animal (18) to exit from of a milking stable (14) in which the animal is standing during a milking session and in connection to which the expelling device is configured to be arranged, wherein in the milking stable (14) is of a type which has a front wall element (15) and lateral wall elements (16, 17) and is configured to house an animal (18) that is being milked in said milking stable (14) with its head directed to and close to said front wall element (15). The expelling device comprises a sheet (1) configured to move vertically from an elevated position to a position adjacent to a front end of the milking stable (14) and adjacent to a lateral wall element (16) of the milking stable (14).
Patent AU-2018269372-A1 (AU)
Title: Fundus image capturing
Inventor: MYERS THOMAS A
IPC: A61B3/14
Filed: 2018-05-16
Abstract: An apparatus for producing a fundus image includes: a processor and a memory; an illumination component including a light source and operatively coupled to the processor; a camera including a lens and operatively coupled to the processor, wherein the memory stores instructions that, when executed by the processor, cause the apparatus to capture fundus images and provide controls for re-imaging the fundus.
Patent AU-2018272914-A1 (AU)
Title: Diagnostics of mild or advanced periodontitis based on salivary IL-1beta and MMP-9
Inventor: KOOIJMAN GERBEN
IPC: G01N33/68
Filed: 2018-05-23
Abstract: Disclosed is an in vitro method for assessing whether a human patient suffering from periodontitis has mild periodontitis or advanced periodontitis. The method is based on the insight to determine a selection of three biomarker proteins. Accordingly, in a sample of saliva a patient suffering from periodontitis, the concentrations are measured of the proteins Interleukin-1β (IL-1β), Matrix metalloproteinase-9 (MMP-9) and at least one of the proteins: Interleukin-6 (IL-6), and Matrix metalloproteinase-3 (MMP-3). Based on the concentrations as measured, a value is determined reflecting the joint concentrations for said proteins. This value is compared with a threshold value reflecting in the same manner the joint concentrations associated with advanced periodontitis. The comparison allows assessing whether the testing value is indicative of the presence of advanced periodontitis or of mild periodontitis in said patient. Thereby, typically, a testing value reflecting a joint concentration below the joint concentration reflected by the threshold value is indicative for mild periodontitis in said patient, and a testing value reflecting a joint concentration at or above the joint concentration reflected by the threshold value, is indicative for advanced periodontitis in said patient.
Patent AU-2018276725-A1 (AU)
Title: Lactobacillus curvatus WIKIM55 having activity of promoting hair growth, and composition containing same.
Inventor: CHOI HAK JONG
IPC: A23K10/16
Filed: 2018-05-30
Abstract: The present invention relates to a novel Lactobacillus curvatus WIKIM55 isolated from kimchi, and a composition containing the same. The Lactobacillus curvatus WIKIM55 according to the present invention is a probiotic having activities of promoting hair growth and can be diversely applied for intestinal regulation and promotion of hair growth in humans or animals.
Patent AU-2018282461-A1 (AU)
Title: Intragastric device for treating obesity
Inventor: SHARMA VIRENDER K
IPC: A61F5/00
Filed: 2018-12-21
Abstract: An intragastric device configured for deployment in a stomach of a person comprises a catheter having a housing and a lumen extending therethrough, a first wire mesh structure having a pre-deployment shape that is compressed within the lumen of the catheter, a post deployment shape that is expanded within the stomach of the person, and one or more openings 5 on an upper portion of the first wire mesh configured to permit food to enter the device, and a second wire mesh structure having a pre-deployment shape that is compressed within the lumen of the catheter, a post-deployment shape that is expanded within the stomach of the person, and one or more openings on a lower portion of the second wire mesh configured to permit food to exit the device. The intragastric device also includes a connection to flexibly couple a lower 0 portion of the first wire mesh structure to an upper portion of the second wire mesh structure such that the two wire mesh structures are in fluid communication with one another. Food enters the upper portion of the first wire mesh structure, passes through both wire mesh structures, and then exits the lower portion of the second wire mesh structure. Optionally, a sleeve is coupled to the lower portion of the second wire mesh structure and extends into a 5 duodenum of a person. WO 2017/052694 PCT/US2016/028509 ,113 114 18 Nj
Patent AU-2018282485-A1 (AU)
Title: Cartridge, process cartridge and electrophotographic image forming apparatus
Inventor: UNEME TETSUSHI
IPC: G03G21/18
Filed: 2018-12-21
Abstract: CARTRIDGE, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS A process cartridge (P) detachably mountable to an electrophotographic image forming apparatus including a main assembly side drive transmission member (62) and a main assembly side urging member (80), the cartridge including a rotatable photosensitive drum (4); a rotatable developing roller (6) for developing a latent image formed on the drum, the developing roller contactable to and spaceable from the drum; an urging force receiving portion (45a) for receiving an urging force from the urging member to space the roller from the drum; a cartridge side drive transmission portion (74) capable of coupling with the main assembly side drive transmission member to receive a rotational force for rotating the roller; a releasing member (72) capable of urging the main assembly side drive transmission member to decouple the cartridge side drive transmission member from the main assembly side drive transmission member by the urging force receiving portion receiving the urging force from the main assembly side urging member. 21R77f;A 1
Patent AU-2018282498-A1 (AU)
Title: System and methods for controlled mud cap drilling
Inventor: FOSSLI BØRRE
IPC: E21B21/00
Filed: 2018-12-24
Abstract: Abstract A subsea drilling method for controlling the bottom hole annular pressure and downward injection rate during mud cap drilling operations from a mobile offshore drilling unit with a low pressure marine riser and subsea blowout preventer. The method called controlled mud cap drilling uses the hydrostatic head of a heavy annular mud (fluid) managed or observed in order to balance the highest pore pressure in the well and to control the injection rate, by using a subsea mud lift pump and a control system to regulate the process. WO 2017/195175 PCT/IB2017/052823 14 a 35c V
Patent AU-2018290749-A1 (AU)
Title: Compositions and methods for identifying and treating resistance to CTLA4 antagonists in leukemia
Inventor: BACHIREDDY PAVAN
IPC: C07K16/28
Filed: 2018-06-26
Abstract: The present invention relates to compositions and methods for identifying and treating resistance to CTLA4 antagonists in neoplasia. In particular, the invention relates to compositions and methods for use in identifying and treating Ipilimumab resistant forms of leukemia.
Patent AU-2018311770-A1 (AU)
Title: Sensor unit and air conditioner
Inventor: YAMASHITA TETSUYA
IPC: A61B5/113
Filed: 2018-07-19
Abstract: This sensor unit (1) comprises a radar (40), a substrate (41) on which the radar (40) is mounted, a cover member (12) that covers the radar (40) and the substrate (41), and an attachment member (13) for attaching the substrate (41) to the cover member (12) such that a transmission/reception surface (40a) of the radar (40) is set apart from the cover member (12) across a prescribed gap.
Patent AU-2018311981-A1 (AU)
Title: Methods for treating active eosinophilic esophagitis
Inventor: RADIN ALLEN
IPC: A61P1/00
Filed: 2018-08-03
Abstract: The present invention provides methods for treating, preventing or reducing the severity of active eosinophilic esophagitis. In certain embodiments, the present invention provides methods of increasing esophageal distensibility. The methods of the present invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4/ interleukin-13 (IL-4/IL-13) pathway inhibitor such as an anti-IL-4R antibody.
Patent AU-2018312964-A1 (AU)
Title: Dental implant assembly
Inventor: ENGMAN FREDRIK
IPC: A61C8/00
Filed: 2018-08-09
Abstract: A dental implant assembly comprising a healing component removably attachable to a coronal end of a dental implant and an impression component having an outer surface, an upper portion and a lower portion and being removably attachable to the healing component. The healing component has an internal bore for receiving at least part of the lower portion of said impression component therein and the internal bore having a shoulder on an inner surface thereof acting as an axial locator providing an endstop for axial movement of said impression component within said bore. The assembly further comprises a rotational locator limiting rotational movement between said impression component and said healing component, the rotational locator comprising a formation on said outer surface of the impression component and/or a formation on said inner surface of said bore of the healing component. Using this assembly, a digital impression recording positional information about the dental implant can be taken without having to remove the healing component from the implant.