baber/WOPTO huggingface dataset:
Patent CA-2409991-A1 (CA)
Inventor: ZHU ZHENPING
IPC: A61P35/00
Filed: 2001-05-24
Abstract: La présente invention concerne une protéine bispécifique de liaison à l'antigène. Le procédé selon l'invention consiste à optimiser l'avidité desdites protéines bispécifiques de liaison à l'antigène pour le(s) antigène(s), et à conserver dans le même temps leur capacité à faire office d'anticorps naturel, notamment leur capacité à activer la cytotoxicité induite par des compléments et la toxicité cellulaire dépendant des anticorps. Or, les immunoglobulines IgG naturelles sont monospécifiques et bivalentes, c'est-à-dire qu'elles possèdent deux domaines de liaison spécifiques du même épitope. En revanche, l'immunoglobuline du type IgG selon l'invention est bispécifique et bivalente dans la mesure où elle comporte un domaine de liaison sur chaque chaîne légère spécifique d'un épitope et une domaine de liaison sur chaque chaîne lourde spécifique d'un second épitope. De par leur conception, les protéines de liaison à l'antigène selon l'invention, peuvent être produites avec efficacité, de manière que la quasi totalité des protéines de liaison à l'antigène produites soient assemblées selon la configuration voulue.
Patent CA-2411690-A1 (CA)
Title: Forage preservative applicator system
Inventor: DOHRMANN ROGER W
IPC: A01D75/00
Filed: 2002-11-13
Abstract: A forage preservative applicator system for efficiently and accurately providing forage preservatives to forage during harvesting. The forage preservative applicator system includes a support base, a reservoir positionable upon the support base for storing a volume of biological solution, a valve fluidly connected to the reservoir, a pump fluidly connected to the valve, and a dispensing tube fluidly connected to the pump for dispensing the biological solution into the forage being harvested. A flush container is preferably attached to the reservoir and fluidly connected to the valve far allowing flushing of the dispensing tube. At least one ice pack is preferably utilized within the reservoir for maintaining the temperature of a biological solution at the desired temperature for extending the useful life of the biological solution.
Patent CA-2415754-A1 (CA)
Inventor: STERN EDITH
IPC: G08G1/0962
Filed: 2001-07-23
Abstract: Le système et le procédé de l'invention sont destinés à la détermination et la notification automatisées de la proximité; ils servent à permettre à un usager ou un client d'une entreprise ou d'un autre établissement (p.ex., d'une bibliothèque publique, d'une installation nationale, etc.) d'obtenir automatiquement un service prédéterminé, à l'arrivée à une destination associée à l'entreprise ou l'établissement, et ce sans devoir communiquer oralement avec les représentants de l'entreprise/établissement. Un dispositif de communication portatif et sans fil est transporté par les utilisateurs de ces services. Le dispositif, désigné PLAD ("pervasive location aware device", ou "dispositif sensible à la position prédominante") reçoit un programme et des paramètres de notification de proximité associés à chaque destination à visiter, lorsque le service est réservé en fonction de la destination. A mesure que l'utilisateur suit ces destinations, le PLAD est actionné et utilise les paramètres et informations du programme acquises pendant le processus de réservation afin d'effectuer une transmission de notification de proximité caractéristique de cette invention lorsque le dispositif atteint une gamme prédéterminée de proximité par rapport à la destination. A cette fin, le PLAD calcule la distance jusqu'à chaque destination valable en ce moment et à laquelle un service est réservé, et envoie un signal de notification de proximité à une adresse associée à une destination correspondante lorsque la distance jusqu'à cette destination est inférieure à une valeur de rayon limite, acquise pendant le processus de réservation. L'équipement récepteur à cette adresse utilise le signal de notification de proximité pour exécuter rapidement un service réservé lorsque l'utilisateur du PLAD arrive à la destination respective. Le PLAD peut aussi être utilisé dans un contexte opposé, lorsque son utilisateur se trouve dans un lieu déterminé, et le service est fourni à ce lieu par un véhicule transportant un autre PLAD, manipulé par une entreprise/établissement, et ce pour prévenir l'utilisateur de l'arrivée proche de ce véhicule.
Patent CA-2416644-A1 (CA)
Inventor: WOOD CHARLES
IPC: E04G11/38
Filed: 2003-01-20
Abstract: A system of interconnecting structural components for supporting and forming suspended concrete stabs that allow removal of form panels without disturbing the slab support posts (shores). Additional features of the system accommodate changes in suspended slab thickness, horizontal slab dimensions that are not multiples of the basic component dimensions, slab edge cantilevered form panels, attachment to walls and remote manipulation of form panels from the floor below using an erection staff. The primary system components are panels, support posts, telescopic beams, adjustable hanger connections, wall hangers, wall beams, raking shore assemblies and erection/stripping staffs. Form panels are directly supported by the shores without the use of an intermediate member (usually a beam) that is common practice in the concrete forming industry. The system reduces the number of required components that in turn reduces the capital cost to the user and improves his labor efficiency and quality of the concrete surface.
Patent CA-2422251-A1 (CA)
Inventor: DINGEMANS THEODOROUS
IPC: C09K19/38
Filed: 2001-03-15
Abstract: Main chain thermotropic liquid crystal esters, ester-imides, and ester-amides were prepared from AA, BB, and AB type monomeric materials and were end-capped with phenylacetylene, phenylmaleimide, or nadimide reactive end-groups. The resulting reactive end-capped liquid crystal oligomers exhibit a variety of improved and preferred physical properties. The end-capped liquid crystal oligomers are thermotropic and have, preferably, molecular weights in the range of approximately 1000-15,000 grams per mole. The end-capped liquid crystal oligomers have broad liquid crystalline melting ranges and exhibit high melt stability and very low melt viscosities at accessible temperatures.  The end-capped liquid crystal oligomers are stable for up to an hour in the melt phase. These properties make the end-capped liquid crystal oligomers highly processable by a variety of melt process shape forming and blending techniques including film extrusion, fiber spinning, reactive injection molding (RIM), resin transfer molding (RTM), resin film injection (RFI), powder molding, pultrusion, injection molding, blow molding, plasma spraying and thermo-forming. Once processed and shaped, the end-capped liquid crystal oligomers were heated to further polymerize and form liquid crystalline thermosets (LCT). The fully cured products are rubbers above their glass transition temperatures. The resulting thermosets display many properties that are superior to their non-end-capped high molecular weight analogs.
Patent CA-2423295-A1 (CA)
Title: Quick release drill bit for down-hole drills
Inventor: LYON LELAND H
IPC: E21B17/07
Filed: 2001-09-24
Abstract: A retainer device (10) is provided for retaining a drill bit (12) within a percussive drill assembly casing (2). The retainer device (10) includes a generally annular body (16) having a central axis and an inner circumferential shoulder portion (18) disposable within the casing (2) such that the body axis (17) is substantially collinear with a casing axis (2a). The shoulder (17) is deflectable between a first position (P1), where the shoulder (18) is contactable with the bit head (14) to retain the bit (12) within the retainer body (16), and a second position (P2). The second position (P2)is spaced radially outwardly from the first position such that the bit head (14) is displaceable through the body (16) in a direction along the casing axis (2a).  Also, the retainer device (10) includes a spacer (24) that locates the retainer body (16) at a desired axial position within the casing (2) and a centralizer (26) that centers the body (16) about the casing axis (2a).
Patent CA-2424644-A1 (CA)
Title: Preparation of torasemide
Inventor: MCKENZIE DAVID JOHN
IPC: C07D213/74
Filed: 2003-04-07
Abstract: The stable polymorphic form of torasemide, Modification I, is prepared from other, unable torasemide forms, by forming a solution of the starting polymorphic form of torasemide in water and methanol, stirring for at least 20 hours and then phase separating the solid torasemide modificartion I from the liquid medium.
Patent CA-2425072-A1 (CA)
Title: Wt1 fusion polypeptides and methods for wt1 immunotherapy
Inventor: VEDVICK THOMAS S
IPC: A61K48/00
Filed: 2001-10-03
Abstract: Compositions and methods for the therapy of malignant diseases, such as leukemia and cancer, are disclosed. The compositions comprise one or more of  a WT1 polynucleotide, a WT1 polypeptide, an antigen-presenting cell presenting  a WT1 polypeptide, an antibody that specifically binds to a WT1 polypeptide; o r a T cell that specifically reacts with a WT1 polypeptide. Such compositions may be used, for example, for the prevention and treatment of metastatic diseases.
Patent CA-2426144-A1 (CA)
Inventor: BURGER KEITH M
IPC: A61B18/12
Filed: 2000-10-17
Abstract: La présente invention concerne des méthodes et des dispositifs de traitement de la pneumopathie obstructive chronique réversible, et plus particulièrement, un dispositif permettant d'échanger l'énergie avec le tissu des voies aériennes tel que celui qu'on trouve dans les voies aériennes des poumons humains. L'échange d'énergie avec ledit tissu de voies aériennes diminue la capacité des voies aériennes à comprimer et/ou à diminuer, à l'intérieur des voies aériennes, la résistance au flux d'air à travers les voies aériennes. Ladite invention concerne aussi une méthode permettant de diminuer la sensibilité ou la résistance au flux d'air des voies aériennes et implique le transfert d'énergie vers les parois de voies aériennes ou à partir desdites parois afin de prévenir ou diminuer la compression des voies aériennes et autres symptômes des pneumopathies. Le traitement permet de diminuer la capacité des voies aériennes à se contracter au moment d'un rétrécissement aigu des voies aériennes, il permet de diminuer le bouchon dû au mucus des voies aériennes, et/ou permet d'augmenter le diamètre des voies aériennes. Les méthodes décrites dans la présente invention permettent un traitement plus long et/ou plus efficace des pneumopathies que les thérapies auxquelles on a recours d'ordinaire, et supprime les problèmes d'observation du traitement par le patient. Il faut aussi y ajouter des étapes supplémentaires qui permettent de diminuer la capacité du poumon à produire au moins l'un des symptômes de pneumopathie obstructive réversible et de diminuer la résistance au flux d'air à travers un poumon.
Patent CA-2427739-A1 (CA)
Inventor: DAVIDSON JANET
IPC: G06F17/30
Filed: 2001-11-01
Abstract: A system and method for automatically integrating data with guidelines to generate displays containing the guidelines and data. The automated system and method can integrate patient data with treatment guidelines to assist a healthcare provider, such as a physician or the like, in providing treatment to the patient. The system and method employ a data storage component, adapted to store guideline data representing guidelines for assessing a condition of an entity, guidelines for taking action on the entity, or both, and to store feature data representing at least one feature of the entity. The system and method further employ an output device, adapted to output at least one diagram representing the guideline data, with the diagram including at least one component representing a relationship of at least a portion of the feature data to at least a portion of the guideline data. The guideline and feature data could pertain to a medical condition, such as diabetes, and the output device could output the diagram as a display or a printed diagram.
Patent CA-2429924-A1 (CA)
Title: Method and system for delivering targeted surveys and offers to the home using internet devices
Inventor: HARICH AMY
IPC: G06Q30/00
Filed: 2001-03-01
Abstract: Published without an
Patent CA-2429964-A1 (CA)
Title: Membranes ioniques servant a separer du soufre organique de solutions hydrocarbonees liquides
Inventor: SAXTON ROBERT J
IPC: B01D61/24
Filed: 2001-12-21
Abstract: L'invention concerne des méthodes de séparation de composés sulfurés d'un mélange hydrocarboné à l'aide d'une membrane ionique. Des membranes ioniques préférées sont des membranes du type Nafion® (polymères d'acide perfluorosulfonique) ou leurs dérivés. Des applications préférées incluent l'élimination de contaminants de naphtas légers soumis à un craquage.
Patent CA-2431041-A1 (CA)
Title: New drug combinations of norepinehrine reuptake inhibitors and neuroleptic agents
Inventor: WONG ERIK HO FONG
IPC: A61K31/535
Filed: 2001-12-27
Abstract: A composition comprising: (a) a pharmaceutically effective amount of one or more norepinephrine reuptake inhibitors or a pharmaceutically effective salt  thereof; and (b) a pharmaceutically effective amount of one or more neuroleptic agents or a pharmaceutically effective salt thereof is provided.  The composition is useful in treating disorders or diseases of the central nervous system, and particularly useful in treating schizophrenia.
Patent CA-2432558-A1 (CA)
Inventor: MAIWALD FRANK
IPC: D04H1/42
Filed: 2003-06-17
Abstract: A copper casting mold for the continuous casting of steel melts is provided, in the presence of zinc and or sulfur in the thermally most greatly stressed contact region with the steel melt, with an at least single-layer diffusion barrier layer made of at least one metallic/metalloid material.
Patent CA-2434296-A1 (CA)
Inventor: MULLIN JOHN GUILFOYLE JR
IPC: C07D277/40
Filed: 2002-01-18
Abstract: La présente invention concerne de nouvelles diaminothiazoles qui sont des inhibiteurs sélectifs de Cdk4. Ces composés et les sels et esters de ceux ci répondant aux normes pharmaceutiques sont des agents antiprolifération qui conviennent pour le traitement des tumeurs solides ou la lutte contre celles-ci, en particulier des tumeurs du sein, du colon, du poumon et de la prostate. Cette invention concerne aussi des compositions pharmaceutiques contenant ces composés ainsi que des intermédiaires qui interviennent dans la préparation de ces composés.
Patent CA-2435563-A1 (CA)
Title: Long lasting growth hormone releasing factor derivatives
Inventor: BENQUET CORINNE
IPC: A61P5/10
Filed: 2002-02-01
Abstract: This invention relates to growth hormone releasing factor (GRF) derivatives.  In particular, this invention relates to GRF peptide derivatives having an extended in vivo half-life, for promoting the endogenous production or release of growth hormone in humans and animals.
Patent CA-2436095-A1 (CA)
Inventor: EKSTAM CHARLES L
IPC: F02M37/54
Filed: 2002-02-20
Abstract: A diesel fuel delivery system contains a variety of components that individually and in combination improve fuel economy and reduce environmenta l pollution. System improvements include a neck-stabilized check valve member (600), a fuel heating element (140), a screen water separator (118), a stres s relieving groove in a fuel pump cavity, a divider wall in the filter head, a n inverted cup (854) formed in the filter head with improved positioning of th e fuel ports, and a nonspilling filter head for use in retaining fuel while changing the fuel filter.
Patent CA-2437507-A1 (CA)
Title: Method and system for completing a transaction between a customer and a merchant
Inventor: TALBERT VINCENT W
IPC: G06Q20/00
Filed: 2002-02-07
Abstract: A computer-implemented method and system for completing a transaction betwee n a customer (10) and at least one merchant (20), including the steps of: (a) initiating a transaction by the customer (10) with a merchant (20); (b) communicating an authorization request, including customer data and transaction specific data, by the merchant (20) to a transaction system (26) ; (c) authenticating the customer (10) by the transaction system (26); (d) authorizing the transaction by the transaction system (26); (e) communicatin g the authorization response by the transaction system (26) to the merchant (20); and (f) completing the transaction between the merchant (20) and the customer (10). An apparatus for implementing the method is disclosed.</SDOAB >
Patent CA-2438353-A1 (CA)
Inventor: SAKURAI SHIGEO
IPC: F02C7/00
Filed: 2001-06-18
Abstract: An operation monitoring unit 11 for acquiring process data from sensors 10 installed to a gas turbine and operation information of the gas turbine; communication units 12, 14 for transmitting each of said two kinds of data on the gas turbine acquired in the operation monitoring unit 11; an analysis server 16 which calculates values of equivalent operating time using each of the two kinds of data obtained through the communication units 12, 14, the value of equivalent operating time evaluating a degree of damage of a diagnosed position for each of a plurality of degradation -and-- damage modes, and calculates a value of whole equivalent operating time by adding the values of equivalent operating time for the individual degradation-and-damage modes; and a facility management unit 15 client-server systemized using the analysis server 16 and a WWW browser 20 or WWW server 19 are provided. By acquiring the above -described two kinds of data relating to the gas turbine during operating the gas turbine into the analysis server 16 through the communication units 12, 14, a highly accurate analysis result of damage condition can be speedy obtained from values of equivalent operating time for a plurality of degradation -and-damage modes.  Further, it is also possible to provide convenienc e that a person in a remote site can speedy and easily view the analysis results using the WWW  browser 20 through the client server system.
Patent CA-2439093-A1 (CA)
Inventor: NEFF C ANDREW
IPC: G06Q50/00
Filed: 2002-02-20
Abstract: A facility for transmitting a ballot choice selected by a voter (301) is described. The facility encrypts the ballot choice (302) with a first secret known only to the client to generate a first encrypted ballot component. The facility also encrypts the ballot choice with a second secret known only to the client (303), the second secret chosen independently of the first secret, to generate a second encry pted ballot component. The facility then generates a proof (304) demonstrating that the first and second encrypted ballot components are encrypted from the same ballot choice. The facility sends the first and second encrypted ballot components and the proof (311) to a vote collection computer system.
Patent CA-2440885-A1 (CA)
Title: Appareil et methode pour preparer du sable de fonderie
Inventor: MCVANE DUANE ALAN
IPC: B22C5/18
Filed: 2002-03-14
Abstract: L'invention porte sur un appareil et des procédés de préparation de mélanges de sables de fonderie comportant une chambre de prémélange d'eau et d'un liant particulaire où se forme une boue d'eau et de liant qui est ensuite transférée dans un malaxeur ou autre mélangeur de sables de fonderie où elle est mélangée au sable de retour puis extraite en vue de la préparation de moules de fonderie. Le liant est de préférence ajouté en courant tombant tandis qu'une pulvérisation d'eau en disperse les particules avec une énergie suffisamment faible pour ne les dévier de leur trajectoire descendante.
Patent CA-2441619-A1 (CA)
Title: Preparation of epoxy-functional resins
Inventor: POURREAU DANIEL B
IPC: C08F216/14
Filed: 2002-03-01
Abstract: A liquid epoxy-functional acrylic resin is disclosed. The resin comprises 10-90 wt % of recurring units of an epoxy-functional allylic monomer and 10-90 wt % of an acrylic monomer that has a homopolymer Tg less that 0oC. The epoxy-functional allylic monomer has the general structure (formula), R is hydrogen, a C1-C10 alkyl, or a C6-C12 aryl group; A is an oxyalkylene group; and n, which is an average number of oxyalkylene groups, is within the range of 0 to about 15.
Patent CA-2441852-A1 (CA)
Title: Titanium dioxide pigment composition
Inventor: SCHMITT VOLKER
IPC: C09C1/36
Filed: 2002-03-12
Abstract: The invention relates to a titanium dioxide pigment mixture comprising a pigment having high greying stability (pigment type A) and a pigment having increased SiO2 and Al2O3 content in flaky precipitation (pigment type B). Sa id mixture provides, for example in paper, a high level of opacity for sufficie nt greying stability. If necessary, the light-fastness of the paper can be further increased by means of known production-conditioned measures on pigme nt type B.
Patent CA-2442245-A1 (CA)
Title: 4,5-dihydro-1h-pyrazole derivatives having potent cb1-antagonistic activity
Inventor: VAN STUIVENBERG HERMAN H
IPC: A61P25/18
Filed: 2002-09-17
Abstract: The present invention relates to a group of novel 4,5-dihydro-1H-pyrazole derivatives which are potent cannabinoid (CB1) receptor antagonists with utility for the treatment of diseases connected with disorders of the cannabinoid system. The compounds have the general formula (Ia) or (Ib) wherein the symbols have the meanings given in the specification. The invention also relates to methods for the preparation of these compounds, an d to pharmaceutical compositions containing one or more of these compounds as an active component.
Patent CA-2443448-A1 (CA)
Title: Optimized board edger and method of operation thereof
Inventor: WEIRATHMUELLER FRIEDRICH
IPC: B27B5/04
Filed: 2002-07-19
Abstract: In a first aspect of the invention, there is provided a new method for edging a wood board. This method comprises the steps of constructing from the scanned images of a wood board, a virtual entity of the wood board; determining from the scanned images an optimized cut line along the virtual entity; displacing the forward edge of the virtual entity ahead of the leading edge of the wood board; displacing the rear edge of the virtual entity behind the trailing edge of the wood board and sawing the wood board along the optimized cut line on the virtual entity. In another feature, the saw blades inside the board edger are mounted in saw collars and are shifted along the arbor by an electric setworks mounted on the top of the saw box and a shifting arm extending vertically between the setworks and a respective saw collar.
Patent CA-2446187-A1 (CA)
Inventor: MORRIS DEBORAH L
IPC: G01N33/52
Filed: 2002-04-30
Abstract: The subject invention comprises a method for diagnosing a clinical event that occurs in a patient's tissue by conducting diagnostic tests on a patient sample obtained from a substance stream in contact with affected tissue. One of the diagnostic tests is an assay for a molecule released from the tissue during the clinical event, and another diagnostic test is an assay for a molecule that is present in the stream and is modified by the clinical event.  The results of the assays are combined in an algorithm to provide a positive or negative diagnosis of the clinical event. In one embodiment, the clinical event is a myocardial infarction, the sample is blood or a component thereof, the molecule released from the affected tissue is a necrotic marker (e.g., troponin), and the modified molecule in the blood component is ischemia modified albumin. In another embodiment, the clinical event is an ischemic stroke, the sample is blood or a component thereof, the molecule released from the affected tissue is a necrotic marker (e.g., S1OOB), and the modified molecule in the blood component is ischemia modified albumin.