baber/WOPTO huggingface dataset:
Patent NZ-569653-A (NZ)
Title: A method of diagnosis and treatment of cancer involving LM04
Inventor: VISVADER JANE ELLEN
IPC: C12Q1/68
Filed: 2002-09-12
Abstract: Disclosed is a method of monitoring an aberrant cell or a cell growth or a predisposition to the development of an aberrant cell or a cell growth in a subject. The disclosed method comprises: i. contacting cells or cell extracts in a biological sample from said subject with a molecule having specificity and binding affinity for LM04 or antigenic portion of LM04 or epitope on LM04 and screening for the level of molecule-LM04 complex formation; or ii. screening a biological sample from said subject for the level of a transcription product of a gene encoding LM04; wherein an elevated presence of said complex or said expression product relative to a normal cell or cell extract is indicative of an aberrant cell. (62) Divided Out of 531532
Patent NZ-573028-A (NZ)
Title: Substituted pyridyl amide compounds as modulators of the histamine h3 receptor
Inventor: LETAVIC MICHAEL A
IPC: C07D213/65
Filed: 2007-05-25
Abstract: Disclosed are (4-alkyl/cycloalky-[1,4]diazepan-1-yl)-[(aryloxy)-pyridinyl]methanone and (4-alkyl/cycloalky-piperazin-1-yl)-[(aryloxy)-pyridinyl]methanone derivatives as represented by the general formula (I), wherein R1 is alkyl or saturated monocyclic cycloalkyl; m is 1 or 2; X is N or CH; Yis N or CRa; Ra is H, -Z-Ar, -CH2NRbRc, -CN, -CO2alkyl, -CO2H, or -CONRbRc; where Rb and Rc are each independently H or alkyl; and R2 is H or -Z-Ar; with the proviso that one of X and Y is N and one of Ra and R2 is -Z-Ar; where Z is O or S; and Ar is a phenyl or monocyclic heteroaryl group unsubstituted or substituted with one, two, or three R3 substituents; where each R3 substituent is independently selected from the group consisting of: halo, alkyl, OH, alkoxy, alkylthio, cyano, amido and nitro; or a pharmaceutically acceptable salt thereof. Further disclosed is a pharmaceutical composition which comprises a an effective amount of a compound as defined above, for treating a disease, disorder, or medical condition mediated by histamine H3 receptor activity (including conditions such as dementia, Alzheimer's disease, cognitive dysfunction, mild cognitive impairment, pre-dementia, attention deficit hyperactivity disorders, attention-deficit disorders, and learning and memory disorders).
Patent NZ-574239-A (NZ)
Title: Hybrid fusion proteins for malaria vaccines
Inventor: COHEN JOSEPH D
IPC: A61K39/015
Filed: 2007-07-16
Abstract: Disclosed is an immunogenic hybrid fusion protein comprising: a) At least one repeat unit from the repeating region of a type I circumsporozoite protein of P. vivax; b) At least one repeat unit from the repeating region of a type II circumsporozoite protein of P. vivax; and c) Surface antigen S from Hepatitis B virus, or a functional fragment thereof. Also disclosed are compositions comprising the hybrid fusion protein and an adjuvant, and the use of the hybrid fusion protein in the manufacture of a medicament for treating or preventing malaria.
Patent NZ-576922-A (NZ)
Title: Filling prohibiting device for the neck of a vessel which uses vessel geometry and surface tension properties to allow only one directional flow
Inventor: GRANGER JACQUES
IPC: B65D49/00
Filed: 2007-12-06
Abstract: Disclosed is an anti-refilling device. It is designed to be fixed irreversibly to the neck of a container containing a liquid and to be closed by a stopper cap. The device has an axis coinciding with the axis of the neck when it is fixed on the latter. The device presents an axial dispensing duct for the liquid through which a transverse wall extends, fixed irreversibly to the anti-refilling device and provided with a number of traversing channels. Each of the traversing channels is connected to an external opening, directed towards the outside of the container and an internal opening, directed towards the inside of the container. The smallest dimension of the external opening is lower than a critical dimension determined according to the critical surface tension of the material making up the transverse wall. The smallest dimension of said internal opening is greater than the critical dimension.
Patent NZ-577728-A (NZ)
Title: Von willebrand factor- and factor viii-polymer conjugates having a releasable linkage
Inventor: BOSSARD MARY J
IPC: A61K47/48
Filed: 2007-12-27
Abstract: A von Willebrand Factor or Factor VIII moiety-polymer conjugate having a releasable linkage. The linkage is derived from 9H-flouroene and the polymer is a water-soluble polymer, in particular polyethylene glycol (PEG). The conjugate can be used for treating a bleeding disorder.
Patent NZ-578974-A (NZ)
Title: 2-heteroaryl substituted imidazoles, compositions comprising them and methods of their use
Inventor: BAGDANOFF JEFFREY
IPC: A61P29/00
Filed: 2008-02-28
Abstract: Disclosed herein are 2-heteroaryl substituted imidazole compounds of formula I(a), I(b), II(a), II(b), III(a), III(b), wherein the substituents are as defined within the specification, processes for their preparation, compositions comprising said compounds. Said compounds/compositions are useful in the treatment for reducing the number of circulating lymphocytes in a patient, modulating the amount of S1P in a patient, suppressing immune response in a patient, treating, managing or preventing a disease or disorder, wherein the disease or disorder is ankylosing spondylitis, asthma (e.g. bronchial asthma), atopic dermatitis, Behcet's disease, graft-vs-host disease, Kawasaki syndrome, lupus erythematosus, multiple sclerosis, myasthenia gravis, pollinosis, psoriasis, psoriatic arthritis, rheumatoid arthritis, scleroderma, transplant rejection (e.g. of organ, cell or bone marrow), type 1 diabetes or uveitis.
Patent NZ-582695-A (NZ)
Title: An adaptor to minimise the additional distance of a digger bucket from the end of the boom when using a rotation device
Inventor: YRJO RAUNISTO
IPC: E02F3/36
Filed: 2010-01-19
Abstract: An arrangement for fixing a work piece to an end of a boom (1) of a working machine is disclosed. The arrangement allows for rotation of the work piece around three axes. A tilting device is attached to the boom (1) to rotate around a first rotation axis at an articulation pin (5), the tilting device for tilting the work piece about a second axis (15) lying substantially perpendicular to the first rotation axis and lying substantially parallel to a plane through fixing pins of said work piece. The tilting device includes a movable body to which the work piece may be attached directly or indirectly by means of an intermediary piece to rotate about a third axis. The tilting device is fixed to an auxiliary body (9) at two fixing points arranged on substantially opposite ends of the tilting device by fixing pins, the fixing points at the ends of the tilting device defining the second axis (15), the fixing pins substantially not rotating relative to the auxiliary body (9). A coupling section (17) is located at the side of the second axis (15) lying closer to the work piece so as to reduce the distance between the articulation point (17) and the work piece.
Patent NZ-583958-A (NZ)
Title: A carton, a partially formed carton, a method of their making and a blank
Inventor: BOUKREDINE ERIC
IPC: B65D71/36
Filed: 2008-09-28
Abstract: A carton 330 having a reinforced carrying handle, comprising a series of carton walls including a composite end wall, a top wall 314, a bottom wall 318 and a pair of side walls 312, 314. The composite end wall comprises a top end closure panel 324a, 324b hinged to the top wall 314 and having a first-hand gripping means 350a, a first handle reinforcing panel having a second hand gripping means disposed in alignment with the first hand gripping means, and a bottom end closure panel hinged to the bottom wall 318 and having a third hand gripping means disposed in alignment with the first and second hand gripping means. The first handle reinforcing panel 350a is hinged to the top end closure panel by a fold line disposed opposite to and angled acutely to the hinged connection between the top end closure panel and the top wall 314
Patent NZ-586634-A (NZ)
Title: Buoyant actuator with means for opening body to permit water to flow through
Inventor: BURNS ALAN ROBERT
IPC: F03B13/12
Filed: 2008-12-17
Abstract: 586634 A buoyant actuator (19) is disclosed comprising a body defining an exterior surface comprising a plurality of facets (101). The body also includes means for opening the body to permit water flow through the body. A wave energy conversion system (11) using such an actuator is also disclosed.
Patent NZ-589033-A (NZ)
Title: Novel polymorphs of azabicyclohexane
Inventor: HAGEN ERIC J
IPC: A61K31/403
Filed: 2005-08-17
Abstract: The disclosure relates to a composition comprising an acid addition salt of (+)-I-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane enriched for a selected polymorphic form of said acid addition salt of (+)-1-(3 ,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane selected from: Polymorph A, Polymorph B and Polymorph C, each exhibiting an X-ray powder diffraction pattern as measured at crystal sizes of from about 10 to 40 microns characterized by distinguishing peaks at one or more of and at about the 2-theta (degree) values defined in the specification. Also disclosed is a process for producing said Polymorph A, Polymorph B and Polymorph C.
Patent NZ-596510-A (NZ)
Title: Mobile self-contained stone-making and concrete- processing factory
Inventor: TROKE GARY
IPC: B28C5/08
Filed: 2009-05-28
Abstract: A mobile factory 10 for producing concrete products comprises a portable frame 20 for supporting the mobile factory and for enabling the mobile factory 10 to be displaced to a construction site, a receptacle 30 for receiving local aggregate, a batching module 40 for mixing the local aggregate with cementitious material and water to thereby create a batch, a compression station 50 for compressing the batch into a stone product, and a power plant 60 for powering the batching module 40 and the compression station 50. The batching module 40 comprises a measuring module for receiving aggregate and a mixer disposed beneath the measuring module. The mixer has mixing paddles equipped with wear bars.
Patent NZ-596787-A (NZ)
Title: Growth hormone polypeptides and methods of making and using same
Inventor: SILVERMAN JOSHUA
IPC: A61K38/16
Filed: 2010-06-08
Abstract: 596787 Disclosed is a fusion protein, comprising a growth hormone (GH) sequence selected from human growth hormone of SEQ ID NO: 1 and an agonist thereof that is at least 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% identical to the amino acid sequence FPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF, wherein said GH is linked to an extended recombinant polypeptide (XTEN) of at least about 200 amino acid residues, wherein the XTEN is characterized in that: (a) the XTEN sequence comprises at least about 200 contiguous amino acids that exhibits at least 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to a comparable length of an amino acid sequence selected from sequences such as MAEPAGSPTSTEEGTPGSGTASSSPGSSTPSGATGSPGASPGTSSTGS and MAEPAGSPTSTEEGASPGTSSTGSPGSSTPSGATGSPGSSTPSGATGS (b) the XTEN sequence lacks a predicted T-cell epitope when analyzed by TEPITOPE algorithm, wherein the TEPITOPE algorithm prediction for epitopes within the XTEN sequence is based on a score of –9 or greater; (c) it has a subsequence score of less than 10; and (d) the sum of glycine (G), alanine (A), serine (S), threonine (T), glutamate (E) and proline (P) residues constitutes more than about 90% of the total amino acid residues of the XTEN.
Patent NZ-597549-A (NZ)
Title: Tissue repair method and kit - the kit contains a hand held suturing apparatus designed to place and secure a mesh on a body tissue
Inventor: MIZRAHY MOSHE
IPC: A61B17/00
Filed: 2010-06-17
Abstract: Discloses a kit for tissue repair comprising: (A) a mesh placer element; the mesh is attached to the placer element via an application member; (B) a mesh stitcher element for stitching the mesh to tissue, comprising: first and second puncture elements for puncturing tissue; the suture thread is disposed along a portion of first puncture element, where the suture assembly has a mode of operation wherein: the mesh sticher element is designed to close a gap between two distal puncture sites; (C) a tacker for applying a rotary tack for tacking the mesh to tissue comprising: a handle with a first trigger assembly and a second trigger assembly, where the trigger assemblies are coupled to an articulated applicator arm The therapeutic application is for fixing surgical mesh in place during surgery e.g. for a hernia operation.
Patent NZ-597779-A (NZ)
Title: Treatment of inflammatory diseases using placental stem cells
Inventor: EDINGER JAMES W
IPC: A61K35/644
Filed: 2008-02-12
Abstract: 597779 TREATMENT OF INFLAMMATORY DISEASES USING PLACENTAL STEM CELLS Provided is the use of a composition comprising placental stem cells and a matrix or hydrogel in the manufacture of a medicament for treating an individual having scleroderma, mycosis fungoides, or inflammatory bowel disease, wherein said placental stem cells are CD200+, and wherein said placental stem cells do not comprise human totipotent stem cells. The medicament can be combined with various other anti-inflammatory or immunosuppressant drugs.
Patent NZ-597968-A (NZ)
Title: Coated dehydrated microorganisms with enhanced stability and viability
Inventor: CHAIGNEAU PATRICK
IPC: A23L35/00
Filed: 2010-08-13
Abstract: Patent No. 597968 Disclosed is a coated dehydrated microorganism comprising a dehydrated microorganism surrounded by at least one coating, said coating comprising by dry weight at least 25% of hygroscopic salt(s), wherein said hygroscopic salt(s) has a Moisture Uptake Rate (MUR) of at least 20% w/w at 25 oC at 75% relative humidity (RH) after 7 days, and wherein the pH of the coating is compatible with viability of the coated dehydrated microorganism. Also disclosed is liquid coating composition for coating a dehydrated microorganism wherein it comprises at least 25% of a hygroscopic salt or mixture thereof by dry weight of dry solids within the composition, wherein said hydroscopic salt has a Moisture Uptake Rate (MUR) of at least 20% w/w at 25 oC at 75% Relative Humidity (RH) after 7 days, and wherein the pH of said liquid coating composition is from 5.5 to 7.9, preferably from 6 to 7.5.
Patent NZ-599754-A (NZ)
Title: Control of ectoparasites
Inventor: CRAWFORD MICHAEL J
IPC: A01N43/56
Filed: 2008-06-09
Abstract: Abstract - 599754 Disclosed is a method for treating ectoparasites in a non-human mammal, the method comprising administering to the non-human mammal an effective amount of a composition comprising 4-chloro-3 -ethyl-1-methyl-N -[[4-(4-methylphenoxyl)phenyl]methyl]-1H-pyrazole-5-carboxamide (4-chloro-3-ethyl-1-methyl-N-[4-(p-tolyloxy)benzyl]pyrazole-5-carboxamide / tolfenpyrad) or a salt thereof and wherein the ectoparasites are selected from Boophilus spp (cattle ticks), Rhipicephalus spp (ticks in the family Ixodidae), Dermacentor spp, Hyalomma spp, Amblyomma spp, Otobius spp, Ornithodoros spp, Damalinia spp (cattle-biting louse), Bovicola spp (Cattle-biting lice) or Ctenocephalides spp (fleas - a flea genus in the tribe Archaeopsyllini).
Patent NZ-601392-A (NZ)
Title: Live Trap for Trapping Rodents
Inventor: CINK JAMES H
IPC: A01M23/08
Filed: 2009-09-21
Abstract: A live trap 100 is provided for trapping rodents. The live trap includes a housing having an interior space and at least one opening 106 through which rodents enter the interior space of the housing. A first trap mechanism 108 is provided that is positionable in the live trap for trapping rodents within the live trap. A second trap mechanism is provided that is different from the first trap mechanism 108 and positionable in the live trap for trapping rodents within the live trap. The live trap and trap mechanisms are configured for selective releasable securement of each of the respective first and second trap mechanisms in the live trap to permit interchangeable use of the first and second trap mechanisms in the live trap. The first trap mechanism 108 comprises one of a funnel trap mechanism, a swinging gate mechanism, and a ramp mechanism and the second trap mechanism comprises a different one of the funnel trap mechanism, the swinging gate mechanism, and the ramp mechanism.
Patent NZ-610449-A (NZ)
Title: Benzamide derivative with anticancer activity and preparation method and use thereof
Inventor: BAI HUA
IPC: C07C253/30
Filed: 2011-11-03
Abstract: Disclosed is a compound of formula I, such as 4-ethynyl-3-nitrobenzamide, N-methoxycarbonyl-4-ethynyl-3-nitrobenzamide, N-ethoxycarbonyl-4-ethynyl-3-nitrobenzamide and N-propoxycarbonyl-4-ethynyl-3-nitrobenzamide, which is useful for treating cancers.
Patent NZ-611996-A (NZ)
Title: Powder delivery device
Inventor: GREENHALGH PAUL
IPC: A61M35/00
Filed: 2011-12-23
Abstract: A device for the dispensing of medical or surgical powder is of the type in which a generated gas flow entrains the powder to be dispensed and carries the powder from the device via barrel (29). The barrel has a bore including a main portion (294) with a continuous internal surface, and is characterised in that (a) the length of the main portion is at least fifteen times its maximum internal diameter; and/or (b) the internal bore of the main portion is tapered; and/or (c) the barrel has an outwardly flared outlet portion (292).
Patent NZ-613413-A (NZ)
Title: Methods of pest control in soybean
Inventor: VOCK CHRISTOPH
IPC: A01P7/04
Filed: 2012-02-01
Abstract: The disclosure relates a method comprising applying to a crop of soybean plants, the locus thereof, or propagation material thereof, a compound of formula (I), wherein X, R8, and p are as defined in the specification, wherein the method is for controlling and/or preventing infestation of the soybean crop by Euschistus (also known as the stink bug). The method may include combining the compound with an attractant selected from glucose, saccharide, salt, glutamate, citric acid, soybean oil peanut oil and soybean milk.
Patent NZ-616063-A (NZ)
Title: Method for optimizing combustion engines
Inventor: BOVE FABRIZIO
IPC: F02M27/04
Filed: 2012-03-28
Abstract: Disclosed is a method for treating the air fuel mixture to feed to an internal combustion engine, wherein fuel and coolant is magnetically charged and air is oppositely magnetically charged to optimise combustion efficiency. The method for treating an air-fuel mixture fed to an internal combustion engine comprises the following magnetization steps. A) magnetization and treatment of fuel present inside a tank due to at least one immersion container, equipped with a plurality of holes placed in proximity to a fuel duct and containing at least one cylindrical container, equipped with a plurality of holes, in turn adapted to contain a plurality of magnetic elements spaced from each other by the same number of ceramic spacers. B) magnetization of air fed to the internal combustion engine due to at least one pair of magnets, placed on a suction duct in proximity to the engine and adapted to provide the air fed to the engine with a charge with sign opposite that provided to the fuel fed to the engine. C) transfer of the treated fuel of the tank, by means of the fuel duct, into a passage container containing a sequence of curves made by the aforesaid fuel duct, said duct being equipped with at least one pair of magnets adapted to polarize the fuel with an electric charge with the same sign as that which will be produced by the magnetization following subsequent passages of the fuel in the system. D) further magnetization of the fuel present in the fuel duct due to at least one pair of magnets placed directly in contact with said fuel duct and situated in proximity to the system for injecting said fuel into a combustion chamber, having sign analogous to that induced in step C. E) magnetization of water and/or of liquid for cooling the engine due to at least one pair of magnets placed directly on a tube of the cooling water and/or liquid and capable of creating a charge with sign analogous to that induced in steps c, d.
Patent NZ-631670-A (NZ)
Title: Hitch pin and receiver assembly
Inventor: NICK VERBOEKET
IPC: B60D1/02
Filed: 2014-09-12
Abstract: A hitch pin and receiver assembly, comprises a hitch pin 501 having a first end and a second end, including at least one lug 550 proximal to the first end, fastening means 545, 548 proximal to the second end and a shaft 560 extending between the at least one lug and the fastening means, and, a receiver 502 having two apertures 570 adapted to accommodate the shaft and second end of the hitch pin, but not the head. The receiver includes a complementary structure 575 that allows the at least one lug of the hitch pin to abut a receiver insert and substantially prevent translational movement of the receiver insert relative to the receiver when the fastening means are engaged.
Patent NZ-717149-A (NZ)
Title: Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same for treating various diseases
Inventor: CHEN ROGER SHEN-CHU
IPC: C07D495/04
Filed: 2011-02-10
Abstract: Disclosed herein is a compound of formula (II), wherein the variables are defined in the specification, and the use thereof in the treatment of cancer, a disorder associated with angiogenesis, pain, macular degeneration or a related syndrome, a skin disease, a pulmonary disorder, an asbestos-related disorder, a parasitic disease, an immunodeficiency disorder, a CNS disorder, CNS injury, atherosclerosis or a related disorder, dysfunctional sleep or a related disorder, an infectious disease, hemoglobinopathy or a related disorder or a TNFα related disorder. In one embodiment the compound is 3-(4-(4-(2-morpholinoethoxy)-benzyloxy)-1-oxoisoindolin-2-yl)-piperidine-2,6-dione.
Patent NZ-742660-A (NZ)
Title: Variants of chymosin with improved milk-clotting properties
Inventor: VAN DEN BRINK JOHANNES MAARTEN
IPC: A23L11/60
Filed: 2013-05-22
Abstract: The present invention relates to a method for making an isolated chymosin polypeptide variant comprising the steps: (a): making an alteration in a parent polypeptide having chymosin activity, wherein the alteration comprises a substitution in an amino acid position corresponding to position 311; and (b): producing and isolating the altered polypeptide of step (a) and thereby obtaining the isolated chymosin polypeptide variant, wherein the variant has chymosin activity; and wherein: (i): the amino acid position of the parent polypeptide is determined by an alignment of the parent polypeptide with the polypeptide of SEQ ID NO: 1 (bovine chymosin) – i.e. the polypeptide of SEQ ID NO: 1 is used to determine the corresponding amino acid sequence in the parent polypeptide; and (ii): the parent polypeptide has at least 95% sequence identity with the mature polypeptide of SEQ ID NO: 2 (camel chymosin), which is from amino acid position 59 to amino acid position 381 of SEQ ID NO: 2; and wherein the isolated chymosin polypeptide variant has a chymosin activity giving a higher C/P ratio as compared to the C/P ratio of camel chymosin comprising the mature polypeptide of SEQ ID NO: 2; and wherein said method is not performed within a human body. The present invention also relates to chymosin variants produced by such methods, and to methods for making foods or feed products comprising adding an effective amount of the isolated chymosin polypeptides.