baber/WOPTO huggingface dataset:
Patent AU-754515-B2 (AU)
Title: Method of using tetracycline compounds to enhance interleukin-10 production
Inventor: GOLUB LORNE M
IPC: A61P31/12
Filed: 1999-09-10
Granted: 2002-11-21
Abstract: The invention is a method of enhancing endogenous interleukin-10 production in mammalian cells and tissues, which includes administering an effective amount of a tetracycline derivative. The method also includes enhancing interleukin-10 production by administering an effective amount of the tetracycline derivative to a mammal. Preferred tetracycline compounds are tetracycline compounds which have been modified to reduce or eliminate their antimicrobial activity. The method can be used to treat medical conditions in mammals characterized by excessive IL-1 and TNF  alpha  production.
Patent AU-595538-B2 (AU)
Title: Amides of N-acylated amino acids as anticonvulsants
Inventor: KOHN HAROLD L
IPC: A61K31/40
Filed: 1986-08-21
Granted: 1990-04-05
Abstract: The present invention relates to an anticonvulsant composition comprising a compound of the formula: <CHEM> where R, R1, R2 and R3 and n are as defined in claim 1 as effective ingredient, together with a pharmaceutically acceptable carrier, said composition being useful in the treatment of epilepsy and other CNS disorders, and the use of the above effective ingredient in the preparation of an anticonvulsant medicament.
Patent AU-534462-B2 (AU)
Title: Bath additives
Inventor: HERMANN CLAUS
IPC: C11D1/29
Filed: 1980-09-19
Granted: 1984-02-02
Abstract: A bath additive or shower gel, comprising 20 to 70% by weight of a detergent blend (consisting of 10 to 90% by weight of an amine C8-18 fatty alcohol sulphate (optionally ethoxylated) and a metal or ammonium ethoxylated C8-18 fatty alcohol sulphate) and 20 to 60% by weight of a cosmetically acceptable oil, gives improved oil deposition.
Patent AU-636172-B2 (AU)
Title: Detection and treatment of infections with immunoconjugates
IPC: G01N33/569
Filed: 1990-08-22
Granted: 1993-04-22
Abstract: The use of: (a) an antibody or antibody fragment which binds to an epitope on a single species of pathogen or an antigen derived therefrom, or (b) an immunoreactive composite of a plurality of chemically linked antibodies or antibody fragments which bind to a plurality of epitopes on a single species of pathogen or an antigen derived therefrom; said antibody or antibody fragment or composite being conjugated to at least one diagnostic or therapeutic agent to form an antibody conjugate; in the preparation of an agent for use in a method of diagnosis or therapy of a focus of infection, wherein a patient infected with a pathogen is injected parenterally with said antibody conjugate, and the conjugated diagnostic or therapeutic agent is targeted to said focus, whereby the diagnostic or therapeutic function thereof is effected. A sterile, injectable preparation for such use is also provided.
Patent AU-785275-B2 (AU)
Title: Cannabinoid patch and method for cannabis transdermal delivery
Inventor: BROOKE LAWRENCE L
IPC: A61K31/352
Filed: 2001-08-29
Granted: 2006-12-14
Abstract: A transdermal structure (10) is provided for delivering cannabis chemical(s) (14) to one's bloodstream. The structure comprises a backing layer (11) which carries the cannabis chemical(s). The chemicals are contained in a film (35) on the backing layer or within a cavity (12) formed in the backing layer. Alternatively, an opening (43) in a secondary layer (42) that overlies the backing layer may be used to create the cavity. The structure is applied to one's skin so that the cannabis chemicals are in contact with the skin. A polymer material (22) which is mixed with the cannabis and placed in the cavity or a membrane over the cavity may be used to control the flow of cannabis chemical(s) into the bloodstream. In an alternative embodiment, a porous material (34) impregnated with cannabis chemical(s) may be used to hold the chemical(s) in the cavity. Because of the relatively slow transdermal flow rate of cannabis materials, it is preferred to utilize permeation enhancers in conjunction with the cannabis carrier or reservoir matrixes or skin contacting adhesive layers (13) <IMAGE>
Patent AU-694056-B2 (AU)
Title: Method for tracing payment data in an anonymous payment system, as well as payment system in which the method is applied
Inventor: ROOIJ PETER JACOBUS NICOLAAS D
IPC: G07F7/10
Filed: 1996-07-05
Granted: 1998-07-09
Abstract: The invention relates to a method for tracing payment data in an anonymous payment system having electronic payment means, such as so-called "smart cards". According to the invention, the user commits himself to a value (w) which may later be used for the tracing by a payment institution. The value (w) is preferably recorded with the help of a so-called one-way function (F) and an (electronic) signature ( sigma ), so that the payment institution does not dispose of the value itself, but is able to verify it on the basis of the stored derivative (w'') of the value. The invention further relates to a payment means and a payment system for application of the method.
Patent AU-689106-B2 (AU)
Title: Improvements in automatic vehicle location systems
Inventor: PEARCE JOHN NICHOLAS
IPC: G08G1/123
Filed: 1994-05-06
Granted: 1998-03-26
Abstract: PCT No. PCT/GB94/00981 Sec. 371 Date Feb. 8, 1996 Sec. 102(e) Date Feb. 8, 1996 PCT Filed May 6, 1994 PCT Pub. No. WO94/27265 PCT Pub. Date Nov. 24, 1994An automatic vehicle location center includes a control center and a plurality of mobile units. Each mobile unit is able to derive a current position from external radio signals. A prediction is responsive to this current position signal and to predicted motion of the mobile unit to derive a predicted position signal. The predicted and current positions signals are compared and the current position signal is transmitted to the control center in dependence on the result of the comparison. The control center has a predictor, similar to that in each mobile unit, responsive to the current position signal and to predicted motion of the mobile unit to derive a predicted position. This position data is only transmitted from a mobile unit to the control center if the predicted position signal differs significantly from the actual position.
Patent AU-718219-B2 (AU)
Title: Use of aminoadamantane compounds as immunoregulators
Inventor: ELSTNER ERICH F
IPC: A61K31/14
Filed: 1996-08-21
Granted: 2000-04-13
Abstract: The invention is directed to the use of certain aminoadamantane compounds for the preparation of a medicament useful for the treatment of immune deficiency diseases, such as AIDS, wherein the medicament increases the activity of neutrophils in a patient possessing already activated neutrophils through a concentration of the aminoadamantane compound of from 10-6 to 10<-5> M in blood plasma.
Patent AU-590690-B2 (AU)
Title: Asymmetrical ester derivatives of 1,4-dihydropyridine-3, 5-dicarboxylic acid
Inventor: ROBIN JACQUES
IPC: A61K31/44
Filed: 1987-03-19
Granted: 1989-11-09
Abstract: The present invention relates to novel asymmetrical esters derived from 1,4-dihydrophyridine-3,5-dicarboxylic acid, of the formula: <IMAGE>  (I)  in which: R1 represents a C1-C4 alkyl group, R2 represents a C1-C4 alkyl group, a benzyl group, a benzoyl group or a phenyl group optionally substituted by one or more C1-C4 alkoxy, C1-C4 alkyl, cyano, nitro, hydroxyl or trifluoromethyl groups or by one or more halogen atoms, and R3 and R4, which are identical or different, each represent the hydrogen atom, a nitro group or a chlorine atom, their optical isomers and diastereoisomers and also the corresponding addition salts. These novel esters are useful in therapy, especially as antihypertensives.
Patent AU-646014-B2 (AU)
Title: Novel platelet-derived growth factor B chain analogs and method for homogeneous production thereof
Inventor: THOMASON ARLEN READ
IPC: A61K38/22
Filed: 1990-12-17
Granted: 1994-02-03
Abstract: Novel platelet-derived growth factor (PDGF) analogs are provided in accordance with the present invention. Also provided is a method for the production of homogeneous quantities of these novel analogs. The novel analogs of the present invention, when refolded, have substantially the same biological activity as naturally occurring PDGF B109. The method of the present invention employs the use of a stop codon on the c-sis gene, or other coding sequence for a precursor protein of PDGF B109, or analogs thereof, at a position corresponding to a location from about amino acid 111 to about amino acid 160. The method of the present invention results in the production of relatively large homogeneous quantities of recombinant PDGF B analogs from high expression host cells, such as E. coli.
Patent AU-768188-B2 (AU)
Title: System and method for ultrasonic laser testing using a laser source to generate ultrasound having a tunable wavelength
Inventor: LORRAINE PETER W
IPC: G01N29/24
Filed: 2000-07-27
Granted: 2003-12-04
Abstract: A system and method for generating ultrasonic displacements on a remote target. The method of the present invention includes the steps of first using a laser to generate a beam having a first wavelength to produce ultrasonic displacements at the remote target. This laser beam will have a first wavelength which can be modulated to alter characteristics of the ultrasonic displacements. These ultrasonic displacements at the remote target can be optimized to enhance the detection optics for collecting phase modulated light from the second pulsed laser beam either reflected or scattered by the remote target; an interferometer to process the phase modulated light and generate at least one output signal, and means for processing the at least one output signal to obtain data representative of the ultrasonic surface displacements on the surface of the remote target.
Patent AU-784910-B2 (AU)
Title: Lentiviral triplex DNA, and vectors and recombinant cells containing lentiviral triplex DNA
Inventor: DUBART KUPPERSCHMITT ANNE
IPC: C12N15/867
Filed: 2000-10-10
Granted: 2006-07-27
Abstract: The present invention provides nucleic acid, vectors, viruses, and recombinant cells comprising triple-stranded structures, such as those resulting from central initiation and termination of HIV-1 reverse transcription at the center of HIV-1 linear DNA genomes. These triplex structures can act as a cis-determinant of HIV-1 DNA nuclear import, allowing infection of non-dividing target cells. In one aspect, the presence of the DNA triplex sequence in an HIV vector strongly stimulates gene transfer in hematopoietic stem cells. The invention also provides methods of using these triplex structures for making recombinant cells, as well as methods of using the recombinant cells to express proteins of interest both  in vitro  and  in vivo.
Patent AU-660146-B2 (AU)
Title: Hip prosthesis
Inventor: SEKEL RONALD
IPC: A61F2/36
Filed: 1991-06-06
Granted: 1995-06-15
Abstract: PCT No. PCT/AU91/00244 Sec. 371 Date Feb. 1, 1993 Sec. 102(e) Date Feb. 1, 1993 PCT Filed Jun. 6, 1991 PCT Pub. No. WO91/18559 PCT Pub. Date Dec. 12, 1991A femoral prosthesis adapted for insertion into the medullary cavity of a femur. The prosthesis including a distal shaft, a neck portion detachable from the distal shaft and a joint head detachable from the neck portion. The distal shaft having two spaced tapered threaded portion thereabout with differing pitch to prevent undesired counter rotation of the prosthesis thereby preventing axial withdrawal of the distal shaft from the femur.
Patent AU-749460-B2 (AU)
Title: Phthalocyanine and use of phthalocyanine as a marking agent
Inventor: MEYER FRANK
IPC: C10L1/22
Filed: 1998-05-13
Granted: 2002-06-27
Abstract: Phthalocyanines of the formulawhereMe is twice hydrogen, twice lithium, magnesium, zinc, copper, nickel, VO, TiO, AlCl, AlOH, AlOCOCH3, AlOCOCF3, SiCl2 or Si(OH)2,at least four of the radicals R1 to R16 are each independently of the others a five- or six-membered saturated nitrogen-containing heterocyclic radical which is bonded to the phthalocyanine structure via a ring nitrogen atom and which can additionally contain further hetero atoms, andany remaining radicals R1 to R16 are each hydrogen, halogen, hydroxysulfonyl or C1-C4-dialkylsulfamoyl,subject to the proviso that tetrakispiperidinylphthalocyanine shall be excluded,and heterocyclyl-substituted phthalocyanines are useful for marking liquids, in particular mineral oils.
Patent AU-685532-B2 (AU)
Title: Short-acting dihydropyridines
Inventor: ANDERSSON KJELL HJALMAR
IPC: C07D211/90
Filed: 1994-11-03
Granted: 1998-01-22
Abstract: PCT No. PCT/SE94/01031 Sec. 371 Date Dec. 14, 1994 Sec. 102(e) Date Dec. 14, 1994 PCT Filed Nov. 3, 1994 PCT Pub. No. WO95/12578 PCT Pub. Date May 11, 1995Compounds of the general formula    <IMAGE>  I  wherein R1 and R2 are independently selected from the group consisting of hydrogen, chloro, bromo, nitro, cyano, trifluoromethyl, and R3 and R4 are independently selected from straight or branched lower (1-5 carbon atoms) alkyl groups, and including all optical isomers, provided that when R3 is methyl and R4 is tert.-butyl, then R1/R2 are not hydrogen/hydrogen, hydrogen/2'-trifluormethyl, 2'-chloro/3'-chloro, and when R3 is methyl and R1/R2 is hydrogen/3'-nitro, then R4 are not methyl, ethyl, propyl, iso-propyl, tert.-butyl, processes for their preparation, pharmaceutical preparations containing them and the use of the compounds in lowering the blood pressure.
Patent AU-759482-B2 (AU)
Title: Human defensin Def-X, gene and cDNA, composition containing same and diagnostic and therapeutic applications
Inventor: BOUGUELERET LYDIE
IPC: C12N5/06
Filed: 1998-08-28
Granted: 2003-04-17
Abstract: The present invention relates to a novel human polypeptide defensin Def-X, genomic DNA and cDNA encoding Def-X, vectors containing Def-X encoding polynucleotides, and cells transformed with these vectors. The invention also provides for the use of Def-X polypeptides as an antibiotic, a cytotoxic, repair, and endocrine regulatory agent, and as pesticide. Def-X can also be used as agent, a cosmetic or pharmaceutical compositions for the treatment of microbial infections, in particular bacterial, fungal, and viral infections, parasitic infections, cancer, inflammation, and immune deficiencies. The invention provides diagnostic methods and kits for the determination of a microbial or parasitic infection and/or inflammation; also provided are methods of screening for predisposition to immune deficiencies or cancer.
Patent DE-2038991-B2 (DE)
Title: Hot water central heating supply pipe work - has flexible plastics flow and return pipes protected by plastics tubes
IPC: F24D3/10
Filed: 1970-08-05
Abstract: Supply pipe attachment for a hot water central heating installation having riser and downcomer pipes for the flow and return systems, partic. for a circulating pump system has at least one flow header attached to each riserpipe with a flow and a return pipe running to each radiator. The connecting flow and return pipes (4, 5) which run to each individual radiator (6) are produced from flexible plastic material and there supply pipes (4, 5) are laid in a flexible plastics protective tube.
Patent DE-2062853-B2 (DE)
Title: Power factor regulation for rotating frequency changer - allowing reactive current variation during overload peaks for optimum use of commutating machine
IPC: H02K47/20
Filed: 1970-12-21
Abstract: The regulator is intended for use with a motor-generator set, normally an asynchronous machine driving a single phase synchronous machine, for example for supplying a railway tractions system as 16 2/3 Hz. Attached to the motor is a power factor correction machine coupled to the motor rotor. At normal loads the motor is held at a fixed power factor, typically unity. When a sudden overload occurs the fixed power factor condition can lead to the demand for very high voltages from the compensating machine. A voltage limit of the regulator is prevented from being exceeded by reducing the phase compensation of the asynchronous machine. This is achieved by influencing the set value of the regulator working in this direction by measured values. Thus, compensating machines with less iron can be employed.
Patent DE-2102090-B2 (DE)
Title: Variable span aircraft wing - has movable outer portion partly covering inner portion and supported by main spar extension
IPC: B64C3/54
Filed: 1971-01-16
Abstract: The variable span aircraft wing has a conventional fixed inner portion and a movable outer portion. That part of the latter inboard of the line of action of the resultant aerodynamic force on it when extended is configured to fit closely over the inner portion. A cantilever-rail extension of the main wing spar projects into the outer portion and carries load-transmitting rollers parallel, and located close to, the line of action. When the wing is fully extended these rollers are up against a stop at the end of the rail.
Patent DE-2142506-B2 (DE)
Title: Fork lift truck combined steering and braking system - has hydraulic rear wheel brakes operated via fixed and variable throttles by front wheel steerage linkage
IPC: B62D11/08
Filed: 1971-08-25
Abstract: The combined steering and braking system is for a mobile crane, fork truck or similar vehicle. It comprises a steering linkage (3) for the steerable wheels (1a, b) which is coupled to a control system (4, 5, 11; 4', 6.12) connected (13) to a hydraulic pump (14) to control the supply to (7, 8) the brake cylinder (17, 17') of the relevant rear wheel (24a, b) and the return to (7a, 8a) drain. Each control system comprises a fixed throttle (11, 12) in a bypass line (9, 10) between the supply (13) and return lines (7a, 8a) and a variable throttle (5, 6) operated (4, 4') by the steering linkage (3). The supply lines (7, 8) to the brake cylinders connect to a point between the two throttles (11, 5 and 12, 6).
Patent DE-2145783-B2 (DE)
Title: Centrifugal friction clutch, engaging above given drive speed - has spring loaded slide bush maintaining engagement when speed drops again
IPC: F16D43/18
Filed: 1971-09-14
Abstract: The centrifugal friction clutch comprises a clutch half (12) on the drive shaft (10), a driven clutch half (20), and centrifugal weights (18) which produce automatic frictional engagement above a given min. speed. A locking bush (32), slidable on the shaft, maintains engagement when the speed subsequently drops below that given value. The shaft clutch half carries double ended (16,38) levers (14) on pivots at right angles to the shaft axis. The weights, which are arranged inside the driven clutch half, are engaged by one end (16) of each lever, whilst the other ends (38) are in contact with the inner conical surface of a spring-loaded (34) locking bush, when the clutch is engaged.(DS).
Patent DE-2215917-B2 (DE)
Title: Rear light cluster for vehicles - has reflector with direct mirror and chrome surfaced edge holding frame
IPC: F16B13/10
Filed: 1972-04-01
Abstract: The main patent describes a complete light fitting incorporating a reflector, a seal to prevent ingress of dirt and moisture and a fitting system. This addition makes manufacture, assembly and fitting easier. The reflector (1) has a directly applied chemical or galvanised mirror finish on a plastic base. It has an outer cover seal (25) of foam plastic. The external cover (13) has an edge frame (26) that fits in a groove cut in the base with a seal (8) being fitted in the groove. The edge frame (26) has a chrome lacquer finish.
Patent DE-2254129-B2 (DE)
Title: Advancing mine gallery coal cutter and conveyor - has towed plates on stops on cylinders engaging hollow guide rail
IPC: E21C35/12
Filed: 1972-11-04
Abstract: On the forward-moving appliance for extracting coal, or similar, and carrying it away, in mine galleries, the extracting machine is guided on a rail with guide channels, on the side of a conveyor. It is moved by cylinder assemblies along the gallery. The guide rail (11) is a self-rail, directly engaged by the forward movement cylinders (17). These have stops (20) on the other side, retaining a towed walling section (19) made of sheet metal plates. Between these and the guide rail are devices (22) guiding a scraper chain or other conveyor belt. The cylinders may be supports for the conveyor.
Patent DE-2749006-B2 (DE)
IPC: G04C10/00
Filed: 1977-11-02
Abstract: A mechanically operating pendulum clock is provided with an electronic correcting device which comprises a quartz oscillator. An electronic frequency divider generates from the oscillation frequency of the quartz oscillator a frequency equal to that of the pendulum. A permanent magnet is arranged on the pendulum to cooperate with a control coil forming an electro-mechanical converter. The control coil is effective at least in the two turning positions of the pendulum. A contact-free pendulum sensor is also provided. A proportional electronic control device includes a converter which produces rectangular signals from the signals emitted by the quartz oscillator and the sensor, and a comparator is adapted, depending upon the reciprocal phase position of the quartz oscillator and sensor signals to transmit delay or acceleration signals to the control coil as well as opposing acceleration or delay signals to the control coil but phase-shifted by 180 DEG .
Patent FR-2663512-B2 (FR)
Inventor: LATREYTE SUZANNE
IPC: A23N7/02
Filed: 1990-06-21
Granted: 1992-10-09
Abstract: The invention concerns a machine for treating produce for peeling it, in particular a nut-husking machine. This machine comprises a tank (1) with a cylindrical wall, a rotary disk (10) dotted with a plurality of teeth (16) projecting above the disk by an adjustable height, means (4-9) for driving the disk into rotation, a sliding gate (24) to recover the processed produce, means for evacuating the wastes and liquid that include a passage (15 ) on the disk circumference, a ring (21) in this passage and a bottom (2) associated with a spout (3), and means distributing the liquid which include a distributor (12) fixed to the center of the disk (10) in order to eject the liquid at the disk in the centrifugal direction.
Patent IE-S62629-B2 (IE)
Title: Open and reseal device (lever type)
Inventor: KELLY MARTINA
IPC: B65D83/00
Filed: 1994-03-22
Abstract: The invention depicts a method of opening and impermanent resealing containers in order to delay the deterioration rate of the product within and to prevent spillage. The design of the device is critical for it's proper operation and so it is capable of two functions by using one lever action i.e. opening and resealing. The device contains 2 seals to ensure maximum protection against spillage. The device also contains a release tab which allows easy reopening without exerting to much pressure and so a lever action takes place by the release tab in the opposite direction also.
Patent IE-S70129-B2 (IE)
Title: Container for use in bulk transportation and storage of fruit and vegetables
Inventor: BROWNE VINCENT
IPC: B65D88/00
Filed: 1995-12-04
Abstract: A container used for bulk transportation of fruit and vegetables consists of a metal cage. Downwardly projecting lugs are provided for mating with a conventional wooden pallet. The container can be stored in premises having high quality flooring without damage to the latter, for this purpose the container is placed resting on a pallet.
Patent IE-S80776-B2 (IE)
Title: Apparatus for selecting a suitably dimensioned buttress
Inventor: WOOD ALFRED EDWARD
IPC: A61B19/00
Filed: 1998-08-26
Abstract: The invention concerns an apparatus for selecting a suitably dimensioned buttress for reconstruction of an annulus of a mitral valve. The apparatus comprises a segment member having a chord to arc length ratio of about 1:2, the chord length approximately relating to the maximum depth of the anterior mitral leaflet from its base to its commissure with the posterior mitral leaflet. Preferably, the chord length approximates twice the maximum depth of the anterior mitral leaflet. A series of such apparatus, of graduated chord length, are provided as a kit of parts to a cardiac surgeon for use in selecting a suitably dimensioned buttress for mitral valve reconstruction for the particular patient involved.