baber/WOPTO huggingface dataset:
Patent JP-2594743-B2 (JP)
IPC: C12N5/00
Filed: 1993-06-22
Granted: 1997-03-26
Abstract: A method for preparing and isolating a transformation vector containing CSF/cDNA is described. The method comprises:  preparing RNA from a cell that produces CSF;  preparing polyadenylated messenger RNA from said RNA;  preparing single stranded cDNA from said messenger RNA;  converting the single stranded cDNA to double stranded cDNA; inserting the double stranded cDNA into transformation vectors and transforming bacteria with said vector to form colonies; picking pools of 200 to 500 colonies each and isolating plasmid DNA from each pool; transfecting the plasmid DNA into suitable host cells for expressing CSF protein; culturing the transfected cells and assaying the supernatant for CSF activity; and selecting CSF positive pools and screening the colonies used to make the pool to identify a colony having CSF activity. Also described are a cDNA coding for a protein having CSF activity (i.e. CSF/cDNA), a microorganism or cell line transformed with a recombinant vector containing such CSF/cDNA, and a method for producing CSF protein by expressing said CSF/cDNA by culturing a microorganism or cell line. The invention also provides a method of purifying the CSF proteins and the purified proteins so produced.
Patent JP-2618697-B2 (JP)
IPC: C07C213/00
Filed: 1988-08-30
Granted: 1997-06-11
Abstract: Polyfunctional ethylenic monomers of the general formula (I): 
<IMAGE>
 where R = cyano, substituted or unsubstituted acyl, substituted or unsubstituted alkoxycarbonyl or substituted or unsubstituted aryloxycarbonyl; each of R1 and R2 denotes -CHR3R4 where R3 and R4, which are identical or different, denote H or an alkyl, alkenyl or aralkyl, or R1 and R2 together form a radical -CH2(CR5R6)n-CHR7- where n = 0 or 1 and R5, R6 and R7, which are identical or different, denote H or CH3. 
<??>Particular monomers: 2-cyano-4,4-dimethoxy-3-hydroxy-1-butene; 2-cyano-4,4-dibutoxy-3-hydroxy-1-butene; 4,4-dibutoxy- 2-ethoxycarbonyl-3-hydroxy-1-butene; 2-butoxycarbonyl-4,4-dibutoxy- 3-hydroxy-1-butene; 4,4-dimethoxy-2-hydroxyethoxycarbonyl-1-butene; 4,4-dimethoxy-2-dimethylaminoethoxycarbonyl-3-hydroxy-1-butene and 4,4-dimethoxy-2-ethoxycarbonyl-3-hydroxy-1-butene.
Patent JP-3640509-B2 (JP)
IPC: B65D83/76
Filed: 1997-08-05
Granted: 2005-04-20
Abstract: An assembly system for sealing a miniature pump to a small container (R), e.g. of a liquid to be atomised, has the body of the pump made with a sleeve (M) which joins the container with an internal or external force fit. The lateral wall of the pump sleeve or container made with a grooved section (1) which acts as a vent and an adjoining smooth section (2). The two surface sections are designed to slide and engage for their whole height with an opposite smooth surface on the container or sleeve, so that the grooved zone is closed gradually on assembly until the two smooth zones meet. The diameter of the grooved zone is the same or not more than 5 per cent smaller than the diameter of the adjacent smooth zone, and the sleeve has a step at its upper end which acts as a stop for the upper edge of the container.
Patent JP-3731980-B2 (JP)
IPC: H04W8/26
Filed: 1997-08-20
Granted: 2006-01-05
Abstract: A computer network system in which an IP address is assigned not only automatically at a destination of a notebook size PC (portable personal computer) 4, but also information relating to shared resources on the network is obtained at the site from a server 1 through a LAN circuit 2, so that the notebook size PC 4 can be used by connecting to the network even in the absence of the administrator. Henceforth, when the user moves within the same building as his own office, it seems that the occasion of using the portable personal computer by connecting to the network such as the Internet and intranet increases. In such a case, connection and disconnection of the network may be repeated frequently, and setting for such operation is facilitated.
Patent JP-H0720466-B2 (JP)
IPC: H04N5/335
Filed: 1986-09-29
Abstract: An endoscopic system comprises a light source for continuously irradiating an object to be photographed; a solid-state camera element for obtaining image signals from the object; a memory for storing a predetermined unit of the image signals obtained from the solid-state camera element; a display converting device for reading out a unit image under a freezing state from the memory; and a intercepting device for intercepting continuous light of the light source when the display converting device reads out a frozen unit image from the memory, such that pulsed light is irradiated onto the object in synchronous with a timing of transferring a unit image from the solid-state camera element.
Patent JP-H07105354-B2 (JP)
IPC: C23C16/22
Filed: 1987-09-25
Abstract: A plasma enclosure (2) containing two electrodes (3 and 4) coupled to a high-frequency generator (5), the substrate (7) being mounted on one of the electrodes. A gas containing at least one silicon compound is introduced into the enclosure and a plasma (8) is created by a radio frequency between the electrodes. The invention is aimed at obtaining a high rate of deposition of semiconductive amorphous silicon on the substrate at the same time as a small number of faults in the deposited film. This objective is obtained by choosing an optimum value of between 30 and 100 MHz/cm for the f/d ratio between the frequency and the distance separating the electrodes, the frequency being between 25 and 150 MHz. At the optimum frequency the rate of deposition is at a maximum and the number of faults is at a minimum. This process can be employed for the deposition of hydrogenated amorphous silicon or of one of its alloys from different gases or gas mixtures, and for producing doped layers. 
<IMAGE>
Patent JP-4444410-B2 (JP)
IPC: A61C7/14
Filed: 1999-10-08
Granted: 2010-03-31
Abstract: An orthodontic bracket comprises a base (3), a bracket body (2) having an arch wire slot (5), and a locking member (20). (20) is in a U-shaped, has a base side portion (22) and a counter base side portion with the same width as the length of (5), extending on its upper side. (22) is located on a base side and extends along (3). (20) is formed of an elastic member having a notched portion in a center of (22). An orthodontic bracket (1) comprises a base (3) secured to a tooth surface, a bracket body (2) having an arch wire slot (5), and a locking member (20) for opening or closing (5). (2) extends perpendicularly from (3), while (5) extends in a mesiodistal direction in a center of the body. (20), which is structured in a U-shaped cross-sectional configuration has a base side portion (22) and a counter base side portion (21) having the same width as the length of (5) and extending on an upper side of (5). (22) is located on a base side and is extended along (3). (20) is formed of an elastomeric member having a notched portion (23) in a center of (21). (2) has a closing stop groove (6) and an open stop concavity (11). The closing (6) is formed at an open edge portion of (5) so as to stop a tip of (20) in a slot closed position. (11) formed at an edge portion of (2) is located away from (6) so as to stop the tip of (20) in a slot open position. A rib (7) is formed in a longitudinally central portion of (6) to bury (6) in correspondence with (23). An independent claim is also included for a tool (70) for the (1) comprising a fulcrum portion engageable with a portion of (2) and an acting portion engageable with a rear end portion of the base side portion. (20) is operated to slide by using the portion of (2) as a fulcrum and an engaging end portion of the rear end portion as a point of application.
Patent JP-2562586-B2 (JP)
IPC: H03K19/177
Filed: 1986-12-05
Granted: 1996-12-11
Abstract: A device having a number of general registers each allocated an input<sup>/</sup>output port and a number internal "buried" state registers. A user-controlled signal permits observation of the contents of the buried state registers at an input/output port although these registers are not allocated an input! output port. Each register is connected to a logic circuit internal to the device by a dedicated feedback path so that all registers can be used to specify states in a state machine sequencer. A fuse-programmable XOR gate permits a user to control generation of signals at the ports by permitting enabling and disabling of an inverting output buffer. Asynchronous reset and synchronous preset of the registers is prov ided. In addition to the dedicated feedback paths, programmable feedback paths are provided. An output inverter can selectably be enabled from internal signals or from an external pin. The input/output circuit can be deployed in banks, each bank selectably receiving the same or a different clock. The registers can be preloaded via an internally-generated signal or from the external pins. In an alternative embodiment, a programmable AND array and a pair of programmable OR arrays, each serving one of the banks, provides a flexible programmable logic array device with observable buried states.
Patent JP-H0380149-B2 (JP)
IPC: C07C235/26
Filed: 1985-12-27
Abstract: The new compound bis(triphenylphosphine)hydrazinomethoxyrhodium (I) is a catalyst for the stereo-specific hydrogenation of demethyl-6-deoxy-6-methylene-5-hydroxytetracycline to  alpha -6-deoxy-5-hydroxy-tetracycline.
Patent JP-H07119638-B2 (JP)
IPC: G01P5/24
Filed: 1990-10-31
Abstract: A measurement system for measuring the time for a signal to pass between two transducers TDR1,2 to allow fluid speed or flow to be determined in a gas meter for example. Each transducer can transmit or receive signals. The system is controlled by a microcontroller 31 and a signal with a phase change acts as a marker which is transmitted from transmitter 21 via matching stage 22,23 from one transducer and is received by the other. On receipt via the matching stage and amplifier 24 it is sampled by capacitor array 25 and detected in detector 29. Amplitude information from array 25 is made available to the microcontroller to compute time of signal travel and hence flow rates.
Patent JP-3594816-B2 (JP)
IPC: G01C3/08
Filed: 1998-10-21
Granted: 2004-12-02
Abstract: In a rangefinder apparatus, a luminous flux is projected from an infrared emitting diode (IRED) toward an object at a distance to be measured and the reflected light of the projected luminous flux is detected by a position sensitive detector (PSD). The signal output from the PSD is arithmetically processed by signal processing circuits and an arithmetic circuit and output as a distance signal. An integrating circuit integrates the distance signal output from the arithmetic circuit as an integration result and a reference voltage, compares the two integration results, and outputs a comparison result signal corresponding to the comparison. According to the signal output from the integrating circuit, a CPU measures the time required for the second integration and detects the distance to the objected according to the time measured. After a lapse of a time from the output of the comparison signal by the integrating circuit, if it is determined that there is an output of the integration result signal, then the measurement of the second integration time is terminated.
Patent JP-4426031-B2 (JP)
IPC: B23C5/22
Filed: 1999-10-26
Granted: 2010-03-03
Abstract: A cutter head (1) is equipped with cassettes (6) and cutting inserts (17) which can be fastened by means of one or more clamping wedges (7, 7a). On the rear side of the individual cassette there is a serration which co-operates with a serration (14) in a rear wall of a recess (5) for the cassette. A bottom wall (10) in the recess is divided into a plurality of part walls (10', 10''), which are spaced-apart by a first abutment surface (21) against which an analogous second abutment surface (22) on the cassette can be pressed. Thanks to this design, the cassette may be rapidly and simply mounted in a basic position in which it is held with good stability. <IMAGE>
Patent JP-2825130-B2 (JP)
IPC: G02B1/04
Filed: 1988-12-15
Granted: 1998-11-18
Abstract: A contact lens of a crosslinked, organic aprotic solvent insoluble, substantially transparent polymer of a derivative of a polyvinyl alcohol having a weight average molecular weight of at least about 2,000, containing an effective amount between about 0.1 and 90 percent, based on the number of hydroxyl groups on said polyvinyl alcohol, of a crosslinked addition reaction product of units of the formula   <CHEM> in the presence or absence of a polymerizable vinylic monomer wherein R<1> is a divalent aliphatic, cycloaliphatic, aryl, aralkyl or alkaryl group; A is -O-, -NH- or -NHCON(R sec )- where R sec  is hydrogen or lower alkyl and A min  is a direct bond; or A is a direct bond and A min  is -O- or -O-CH2-; R<2> is hydrogen or methyl; and R is hydrogen, methyl or -COOR<4> where R<4> is hydrogen or lower alkyl; with the proviso that if R<2> is methyl, R<3> is hydrogen; and wherein the polymerizable vinylic monomer, if present, is hydrophobic or is a mixture of hydrophobic and hydrophilic vinylic monomers in which mixture at least 50 % of vinyl monomers are hydrophobic.
Patent JP-2698779-B2 (JP)
IPC: A61P31/04
Filed: 1995-12-27
Granted: 1998-01-19
Abstract: A method of passively immunizing a mammal against a condition caused by an antigen comprising: administering to the mammal immunizing amounts of an antibody obtained from a domesticated fowl or bovid which has been immunized against the antigen: the mammal being tolerant to the antibody by virtue of having a history of consumption of antibody containing material derived from the egg of a fowl or milk of a bovid.
Patent JP-3499789-B2 (JP)
IPC: A23L17/00
Filed: 1999-12-24
Granted: 2004-02-23
Abstract: The preparation of fish gelatin is new and comprises gelling the skins of fresh or defrosted raw fish, washing the skins and treating them to acid extraction at high temperatures and at an acidic pH.
Patent JP-2799208-B2 (JP)
IPC: C07H19/01
Filed: 1988-12-02
Granted: 1998-09-17
Abstract: Compounds of formula I <CHEM> in which [R<1> and R<2>], [R<3> and R<4>] and [R<5> and R<6>] represent a carbon-carbon bond or two hydrogen atoms;  R<2> additionally represents alkyl;  R<7>, R<8> and R<9> represent groups including H or OH,  R<1><0> has various significances including alkyl and alkenyl;  X and Y represent groups including O and (H,OH); R<1><4>, R<1><5>, R<1><6>, R<1><7>, R<1><8>, R<1><9>, R<2><2> and R<2><3> represent H or alkyl; R<2><0> and R<2><1> represent groups including O, (H,OH) and (H,O-alkyl),  n is 1, 2, or 3, and in addition, Y, R<1><0> and R<2><3>, together with the carbon atoms to which they are attached, may represent a neterocyclic ring,  (with certain provisos) are described. Processes for making the compounds and pharmaceutical formulations containing them, eg for use as immunosuppressive agents, are also described.
Patent JP-3987584-B2 (JP)
IPC: A61F2/60
Filed: 1998-05-28
Granted: 2007-10-10
Abstract: A device in a leg prosthesis provided with a shock- and torque absorber intended to absorb shocks as well as rotational movements which occur when the foot hits the ground during walking, running, jumping etc. and comprising two parts (10, 11) which are telescopically displaceable and rotatable with sect to each other. Mhm device further comprises a first resilient member (12) arranged between the two telescopic pars (10, 11) and said resilient member is arranged to be compressed at a telescopic movement of said parts in a retracting direction, that a second resilient member (19) is attached to the outer telescopic part (10) and limitedly displaceable in the inner telescopic part (11) limiting the telescopic movement as well as the rotational movement thereof in the outer telescopic part (10).
Patent JP-3762426-B2 (JP)
IPC: A61K8/73
Filed: 1993-06-29
Granted: 2006-04-05
Abstract: An oral composition for the treatment of dentinal hypersensitivity containing a dentinal hypersensitivity reducing or relieving amount of an active compound selected from casein, a component of casein, a phosphoprotein and a phosphopeptide, or salts thereof containing the amino acyl residues -Ser (P) -Ser (P) -Ser (P) -where Ser (P) is phosphoserine.
Patent JP-3553062-B2 (JP)
IPC: C07K7/52
Filed: 1993-07-27
Granted: 2004-08-11
Abstract: A method of selectively inhibiting biochemical activity of cells induced by neuromedin B. The method includes the step of contacting cells which contain neuromedin B receptor with a cyclic octapeptide, D-Nal-Cys-Tyr-D-Trp-Lys-Val-Cys-Nal-NH2, or an analog thereof.
Patent JP-2643934-B2 (JP)
IPC: C12P21/00
Filed: 1986-09-02
Granted: 1997-08-25
Abstract: A superoxide dismutase originally found in extracellular body fluids and therefore termed extracellular superoxide dismutase (EC-SOD) is prepared by growing a cell line, preferably of mammalian origin, producing EC-SOD and recovering the EC-SOD secreted from the cells or by inserting a DNA sequence encoding EC-SOD into a suitable vector, introducing the recombinant vector into a host cell, growing the cell and recovering the EC-SOD produced. EC-SOD may be used for the prophylaxis or treatment of diseases or disorders associated with the presence or formation of superoxide radicals.
Patent JP-H0577087-B2 (JP)
Inventor: FUROORA ROORENSU HOORU
IPC: G06F1/04
Filed: 1988-06-20
Abstract: Apparatus and method for providing automatic clock de-skewing for a plurality of circuit boards of a data processing system. In a preferred embodiment, each circuit board is of multi-layer construction and contains a clock distribution chip which includes on-chip automatic clock de-skewing circuitry for providing de-skewed clocks to other chips on the circuit board. In a preferred implementation of the clock de-skewing circuitry, feedback circuitry including a multi-tapped delay line and an accurate reference delay are employed in conjunction with a phase comparator for automatically providing de-skewed clocks at the clock ouputs of the clock distribution chip. The accurate reference delay is advantageously provided by a strip transmission line formed in a conductive layer of the multi-layer board containing the chips. In a preferred implementation of the method, a clock distribution chip includes on-chip automatic clock de-skewing circuitry requiring an accurate reference delay which is advantageously provided by a strip transmission line formed on one of the conductive planes of the multi-layer circuit board containing the chips.
Patent JP-3410734-B2 (JP)
IPC: C12N15/29
Filed: 1992-03-10
Granted: 2003-05-26
Abstract: PCT No. PCT/GB92/00423 Sec. 371 Date Dec. 20, 1993 Sec. 102(e) Date Dec. 20, 1993 PCT Filed Mar. 10, 1992 PCT Pub. No. WO92/15691 PCT Pub. Date Sep. 17, 1992.Biocidal proteins isolated from Mirabilis have been characterized. The proteins show a wide range of antifungal activity and are active against gram-positive bacteria. DNA encoding the proteins has been isolated and incorporated into vectors. Plants transformed with this DNA have been produced. The proteins find commercial application as antifungal or antibacterial agents; transformed plants will show increased disease-resistance.
Patent JP-2587510-B2 (JP)
IPC: H05K3/00
Filed: 1989-06-15
Granted: 1997-03-05
Abstract: The present invention is directed to the use of multiaxially oriented (e.g., biaxially) thermotropic polymers as a substrate material for the preparation of printed wire boards (PWB). In preferred embodiments, the PWB of the present invention comprises a generic, high density, organic multilayer PWB comprising XYDAR TM  and/or VECTRA TM  films, capable of being employed as a high density leadless perimeter and in grid array ceramic chip packages.
Patent JP-3923081-B2 (JP)
IPC: C07D309/28
Filed: 1996-08-07
Granted: 2007-05-30
Abstract: PCT No. PCT/AU96/00495 Sec. 371 Date Sep. 14, 1998 Sec. 102(e) Date Sep. 14, 1998 PCT Filed Aug. 7, 1996 PCT Pub. No. WO97/06157 PCT Pub. Date Feb. 20, 1997Compounds of formula (I), wherein R1 represents NR5R6, wherein R5 represents H or a hydrocarbon group optionally substituted by one or more of Br, Cl, F, I, CF3, NR7R8, CO2R9, CONR7R8, COR9, OR10 or SR10, or a heteroaromatic group; and R6 represents a hydrocarbon group optionally substituted by one or more of Br, Cl, F, I, CF3, NR7R8, CO2R9, CONR7R8, COR9, OR10 or SR10, or a heteroaromatic group; R2 represents a group SO2R9 or COR9; R3 represents H, C1-6-alkyl or C(=NR11)NR12R13; R4 represents H or C1-6alkyl; R7 and R8 each independently represent H, C1-6alkyl or COR9; R9 represents C1-6alkyl optionally substituted by one or more halogen atoms; R10 represents H, C1-6-alkyl or phenyl; R11, R12 and R13 each independently represent H, C1-6alkyl, amino, hydroxy, cyano or nitro; and X represents O or S; and their pharmaceutically acceptable derivatives are neuraminidase inhibitors useful in the treatment of viral infections.
Patent JP-3481940-B2 (JP)
IPC: A61N1/39
Filed: 1992-04-07
Granted: 2003-12-22
Abstract: An implantable atrial defibrillator provides a pulse of defibrillating electrical energy to the atria of the heart in synchronism with sensed R waves in response to non-coincident sensing of an R wave at first and second areas of the heart. The defibrillating pulse is provided after a predetermined number of consecutive R waves are non-coincidently sensed to assure reliable synchronization. The atrial defibrillator is also operational in a marker mode wherein a number of synchronization marker pulses are delivered to the heart for detection on an externally generated electrocardiogram. The atrial fibrillation detector of the defibrillator is normally disabled and is activated when the sensed ventricular activity indicates a probability of atrial fibrillation to conserve a depletable power source. A plurality of lead systems are also described for use with the atrial defibrillator which reduce the quantity of electrical energy required to defibrillate the heart and ensure that the delivered atrial defibrillating electrical energy is substantially confined to the atria of the heart. <IMAGE>
Patent JP-3518768-B2 (JP)
IPC: D04H1/42
Filed: 1995-10-18
Granted: 2004-04-12
Abstract: The invention is a composition useful in preparing elastomeric articles which comprises: (a) from 70 to 95 parts by weight of one or more monovinylidene aromatic monomer conjugated diene block copolymer(s) and (b) from 5 to 30 parts by weight of a thermoplastic polymer comprising one or more of: i) a copolymer comprising a monovinylidene aromatic monomer and an anhydride; ii) polystyrene; iii) polyethylene; iv) an ethylene vinyl acetate copolymer, or a mixture thereof. At least 40 percent by weight of the block copolymers have the conjugated diene block comprised of isoprene. The weight percent of monovinylidene aromatic monomer in the block copolymer is from 10 to 35 percent by weight and the total block copolymer composition contains no more than 4 percent by weight of a diblock. The total parts of block copolymer and thermoplastic polymer is 100 parts. Films prepared from the composition exhibit a creep compliance of 1.5 MPa<-1> or less, a retention of 60 percent or greater as measured according to ASTM-D2991 at 30 minutes, and a permanent deformation of 10 percent or less as measured according to ASTM-D4649. In another embodiment, the invention comprises elastomeric articles comprising the composition of the invention.