baber/WOPTO huggingface dataset:
Patent CA-3091554-A1 (CA)
Title: Formulations for reducing hair loss and/or increasing hair regrowth
Inventor: SEKHAVAT HOUFAR
IPC: A61P17/14
Filed: 2020-08-28
Abstract: The invention relates to formulations comprising 2% to 10% minoxidil, 0.01% to 15% of a prostaglandin analogue, and, optionally 0.01% to 15% finasteride, and to formulations comprising 0.1 to 60% Dapsone and/or 0.1 to 20% Minocycline, tetracycline or doxycycline as an active ingredient. In one embodiment, the prostaglandin analogue is latanoprost. In a preferred embodiment, the composition comprises 5% minoxidil and 0.03% latanoprost. In another preferred embodiment, the composition further comprises 0.1% finasteride. The invention also relates to the use of the formulations to reduce hair loss and/or increase regrowth of hair in a human subject.
Patent CA-3098115-A1 (CA)
Title: Caracteristiques d'interface utilisateur graphique pour mettre a jour un robot conversationnel
Inventor: LIDEN LARS
IPC: G06N3/08
Filed: 2019-04-13
Abstract: L'invention concerne diverses technologies se rapportant à la création et/ou à la mise à jour d'un robot conversationnel. L'invention concerne des interfaces utilisateur graphiques (GUI) qui permettent la mise à jour d'un modèle de réponse mis en oeuvre par ordinateur du robot conversationnel sur la base d'une interaction entre un développeur et des caractéristiques des GUI, les GUI représentant des dialogues entre un utilisateur et le robot conversationnel.
Patent CA-3099920-A1 (CA)
Title: Splicing modulator antibody-drug conjugates and methods of use
Inventor: Pazolli Ermira
IPC: A61K39/00
Filed: 2019-05-31
Abstract: Linker-drug compounds and antibody-drug conjugates that bind to human oncology targets are disclosed. The linker-drug compounds and antibody-drug conjugates comprise a splicing modulator drug moiety. The disclosure further relates to methods and compositions for use in the treatment of neoplastic disorders by administering the antibody-drug conjugates provided herein. In an embodiment, the splicing modulator comprises a pladienolide or a pladienolide derivative.
Patent CA-3100715-A1 (CA)
Title: Inhibitors of integrated stress response pathway
Inventor: DELGADO OYARZO LUZ MARINA
IPC: C07D307/85
Filed: 2019-06-05
Abstract: The present disclosure relates generally to therapeutic agents that may be useful as inhibitors of Integrated Stress Response (ISR) pathway.
Patent CA-3101691-A1 (CA)
Title: Codage de signal optimal base sur des donnees experimentales
Inventor: COULOMBE STEPHANE
IPC: H04N19/587
Filed: 2018-05-09
Abstract: L'invention concerne un procédé et un appareil permettant un codage de signal optimal sur la base de caractéristiques de signal codé associées à des données de référence de paramètres de codage. Des vecteurs de référence de paramètres de codage et des mesures correspondantes de caractéristiques de signal codé sont utilisés pour établir une relation fonctionnelle entre chaque caractéristique et les paramètres de codage. Des vecteurs candidats de paramètres de codage sont identifiés sur la base de limites définies par l'utilisateur à la fois des paramètres de codage et des caractéristiques de signal codé acceptables. Un facteur de mérite est déterminé pour chaque vecteur candidat et le vecteur candidat ayant le facteur de mérite le plus élevé est présenté à un codeur.
Patent CA-3102224-A1 (CA)
Title: Chimpanzee adenovirus chad157 polynucleotides, polypeptides.vectors, compositions, cells and uses thereof
Inventor: AMMENDOLA VIRGINIA
IPC: A61K39/12
Filed: 2019-06-11
Abstract: The present invention relates to isolated polynucleotide and polypeptide sequences derived from novel chimpanzee adenovirus ChAd157, as well as to recombinant polynucleotides, vectors, adenoviruses, cells and compositions comprising said polynucleotide and polypeptide sequences.
Patent CA-3105448-A1 (CA)
Title: Anti-tcr antibody molecules and uses thereof
Inventor: TAN SENG-LAI
IPC: A61K39/00
Filed: 2019-07-03
Abstract: The disclosure provides antibody molecules that bind to TCR Vß regions and multispecific molecules comprising said antibody molecules. Additionally, disclosed are nucleic acids encoding the same, methods of producing the aforesaid molecules, pharmaceutical compositions comprising aforesaid molecules, and methods of treating a cancer using the aforesaid molecules.
Patent CA-3106242-A1 (CA)
Inventor: LANSING JONATHAN C
IPC: C07K16/28
Filed: 2019-07-11
Abstract: La présente invention concerne des compositions et des procédés de constructions de domaine de liaison à l'antigène Fc technologique, les constructions de domaine de liaison à un antigène Fc comprenant au moins deux domaines Fc et au moins un domaine de liaison à l'antigène.
Patent CA-3107263-A1 (CA)
Inventor: YUKI YOSHIKAZU
IPC: A61K39/04
Filed: 2019-08-02
Abstract: The present invention provides a nanogel intranasal vaccine that induces cellular immunity. Specifically, the present invention relates to a vaccine formulation that comprises a complex of a nanogel, a vaccine antigen, and an adjuvant. The vaccine formulation can efficiently induce cellular immunity and also can induce a systemic and mucosal immune response.
Patent CA-3107830-A1 (CA)
Inventor: SHAND ZACHARY
IPC: G01N27/82
Filed: 2021-02-02
Abstract: Systems, methods, and sensor devices for fluid conduit inspection using passive magnetometry are provided. A method of inspecting a fluid conduit using passive magnetometry includes collecting magnetic flux data from inside the fluid conduit without actively magnetizing the fluid conduit, the magnetic flux data representing a residual magnetization of the fluid conduit, and identifying a conduit condition for the fluid conduit using the magnetic flux data. A computer system includes a memory for storing magnetic flux data collected from inside the fluid conduit without active magnetization of the fluid conduit, the magnetic flux data representing a residual magnetization of the fluid conduit; and a processor in communication with the memory and configured to generate an electronic representation of a conduit condition for the fluid conduit based on the magnetic flux data, wherein the electronic representation is stored in the memory.
Patent CA-3110917-A1 (CA)
Inventor: WINNINGHAM MATTHEW
IPC: B29C65/48
Filed: 2019-09-30
Abstract: A system and method for creating protective sports articles. The system includes a last. A liner of flexible material that defines a pocket is provided. A plurality of padding pieces are provided that each have a bottom surface and an adhesive disposed over the bottom surface. The method includes inserting the last into the pocket of the liner. The method also includes positioning the bottom surface of each of the padding pieces over the liner to engage the adhesive against the liner. The method further includes applying pressure to the padding pieces to bond the adhesive of the padding pieces to the liner to secure the padding pieces to the liner and to form a completed article. The method further includes removing the completed article from the last.
Patent CA-3111077-A1 (CA)
Inventor: MAHR ANDREA
IPC: A61P35/00
Filed: 2016-03-24
Abstract: Abstract The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules. Date Recue/Date Received 2021-03-04
Patent CA-3111859-A1 (CA)
Title: Method and device for establishing session
Inventor: YANG HAORUI
IPC: H04W4/10
Filed: 2019-08-12
Abstract: The present application provides a method for establishing a session, which is applied to a terminal device, and includes: sending a session establishment request to a network device, where the session establishment request is used to request to establish a first session, the session establishment request includes first indication information, and the first indication information indicates that the first session is a deactivated session or an activated session; and receiving a response message of the session establishment request from the network device.  If the number of DRBs has reached a number threshold, the terminal device can request the network device to establish a deactivated first session via the first indication information.  When the number of DRBs is less than the number threshold, the terminal device or the network device can activate the first session.
Patent CA-3113121-A1 (CA)
Inventor: LEIJSSEN JACOBUS JOSEPHUS
IPC: F21V31/00
Filed: 2019-09-18
Abstract: L'invention concerne un système anti-encrassement pour réduire et/ou empêcher l'encrassement d'un objet exposé à des conditions d'encrassement en cours d'utilisation, lequel système comprend une pluralité de dispositifs anti-encrassement (26) pour délivrer un rayonnement anti-encrassement à au moins une partie de l'objet et/ou au moins une partie du système anti-encrassement ; et lequel système anti-encrassement comprend en outre : - un système de transmission de puissance comprenant : - un émetteur de puissance inductive (10) comprenant au moins un élément émetteur inductif (12) ; et - une pluralité de récepteurs de puissance inductive (24) comprenant chacun au moins un élément récepteur inductif ; l'émetteur de puissance inductive et la pluralité de récepteurs de puissance inductive étant destinés à être montés sur l'objet dans une configuration fixe l'un par rapport à l'autre de manière à produire ainsi un couplage inductif entre chacun dudit ou desdits éléments récepteurs inductifs et dudit ou desdits éléments émetteurs inductifs de sorte que la puissance peut être transmise par induction quand le système de transmission de puissance est en cours d'utilisation ; et la pluralité de dispositifs anti-encrassement (26) étant configurés de manière à être entraînés à l'aide d'une puissance transmise à partir d'au moins l'un de la pluralité de récepteurs de puissance inductive quand le système est en cours d'utilisation.
Patent CA-3113529-A1 (CA)
Inventor: BENDER JACK
IPC: C22B3/16
Filed: 2019-10-10
Abstract: Disclosed are leaching aids and methods of using the leaching aids. The leaching aids can include one or a combination of compounds. The methods of using the leaching aids can include a process of recovering metal from ore, for example, a process involving leaching, concentration and purification unit operations.
Patent CA-3114063-A1 (CA)
Inventor: SKERLOS STEVEN
IPC: C12M1/107
Filed: 2019-09-30
Abstract: L'invention concerne des bioréacteurs, par exemple pour un traitement biologique, et plus spécifiquement un appareil d'insertion de bioréacteur comprenant des biofilms et des procédés associés. L'appareil d'insertion de bioréacteur prévoit un moyen de circulation du milieu de réaction à l'intérieur du bioréacteur, un support de biofilm et un traitement biologique d'une alimentation d'entrée vers l'appareil de réacteur/d'insertion. L'appareil d'insertion de bioréacteur possède une surface relative élevée pour la fixation d'un biofilm et est en mesure de générer des configurations de circulation complexes et d'augmenter l'efficacité du traitement/conversion biologique dans un réacteur biologiquement actif. La structure de surface élevée incorpore de multiples structures de support à biofilm telles qu'un treillis aux parties d'entrée et de sortie de la structure. Les structures de support à biofilm et les biofilms qui s'y trouvent peuvent augmenter le taux de réaction global du bioréacteur et/ou effectuer une certaine séparation solide/liquide dans le traitement des eaux usées ou d'un autre affluent.
Patent CA-3116529-A1 (CA)
Inventor: PALUMBO ANTONIO
IPC: A01H4/00
Filed: 2021-04-29
Abstract: The present description relates to a plant cutting device for cutting or cloning a plant, and housing the plant for growth. The plant cutting device generally comprises two compaitments that are operatively connected together and displaceable from an open position to a closed position defining an enclosure, a cutter mounted within at least one of the compaitments and configured to cut a plant part when the first and second compaitments are displaced to the closed position, a cut end of the plant part being accommodated within the enclosure; and a growth medium disposed in the first compaitment and/or the second compaitment for contacting the cut end of the plant part allowing for the growth of the plant.
Patent CA-3117536-A1 (CA)
Title: Polypeptides modifies du facteur ix
Inventor: NATHWANI AMIT
IPC: A61P7/04
Filed: 2019-10-30
Abstract: La présente invention concerne des polypeptides modifiés du facteur IX comprenant une mutation à une position correspondant à la position 347 du facteur IX (précurseur) immature de type sauvage, des polynucléotides codant pour les polypeptides, et des traitements utilisant les polypeptides ou les polynucléotides.
Patent CA-3118733-A1 (CA)
Inventor: SCHUESSLER THOMAS
IPC: A61B5/097
Filed: 2019-11-11
Abstract: A module for an oscillometry system of the type having an oscillatory flow source, the module comprises an enclosure adapted to be releasably connected to a core assembly of the oscillometry system. The enclosure defines a breathing flow pathway adapted to be in fluid communication with the oscillatory flow source. A user port is at a first end of the breathing flow pathway configured for receiving a breath of a user. A calibration file specific to the module is programmed as a function of the breathing flow pathway and configured for being used by the oscillometry system to assess breathing parameters for the user.
Patent CA-3119174-A1 (CA)
Inventor: YU CHUNLIAN
IPC: E04F15/00
Filed: 2021-05-19
Abstract: Present invention discbses a foldable three layers chair mat comprising an upper surface rug layer made by woven or knitted rug, allow chair wheels roll on it smoothly; a middle layer made by rigid material seamlessly spliced together by more then tvvo parts, wherein the the rigid layers are glued and bolded by the =rug layer as a hinge, allow to fold; and a lower surfiice anti-skip layer be glued on the lower surface of the rigid layer. The mat has a hard texture but a smooth surface. It can be used not only on had floors such=as wooden fbors but also on soft carpets. Its surtke is covered with soft and beautiful cloth, which is durable and beautiful. The special is that the folds are seamlessly spliced together, and the chair wheels can roll on without any obstacles.
Patent CA-3122039-A1 (CA)
Inventor: PATEL SEEMA
IPC: C07K16/28
Filed: 2019-12-06
Abstract: This invention relates to humanised versions of the murine anti-IL17BR antibody D9.2 which comprise mutations of certain residues within the heavy chain and/or light chain variable domains that display improved expression without deleterious effects on specificity or affinity.The humanised antibodies may comprise a heavy chain variable (VH) domain which comprises a VHCDR1 of SEQ ID NO: 1, a VHCDR2 of SEQ ID NO: 2, and a VHCDR3 of SEQ ID NO: 3, for example, a VH domain of SEQ ID NO: 9, SEQ ID NO: 10 or SEQ ID NO: 11. The humanised antibodies may comprise a light chain variable (VL) domain which comprises a VLCDR1 of SEQ ID NO: 4, a VLCDR2 of SEQ ID NO: 5, and a VLCDR3 of SEQ ID NO: 6, for example a VL domain of SEQ ID NO: 13. Antibodies, pharmaceutical compositions and methods of use, for example in the treatment of cancer are provided.
Patent CA-3123307-A1 (CA)
Title: System and method for making a deck of a bridge or other construction
Inventor: DE LA CHEVROTIERE ALEXANDRE
IPC: E01D19/00
Filed: 2019-12-13
Abstract: A bridge or other construction comprising a deck, in which the deck is designed to be lightweight and durable, such as by including aluminum, and readily installable on a main bearing structure of the bridge or other construction (e.g., without welding and/or without drilling or otherwise creating holes into the main bearing structure of the bridge or other construction), even if the main bearing structure of the bridge or other construction is based on different material (e.g., steel).
Patent CA-3124033-A1 (CA)
Inventor: KINTEA DANIEL
IPC: F15D1/04
Filed: 2020-02-05
Abstract: The invention relates to an angle piece (10) for fluidically connecting fluid lines of a vehicle, wherein the angle piece (10) has a channel portion (12) for altering a flow direction of a fluid about an alteration angle (24), wherein an input flow direction (20) of the fluid into the angle piece (10) and an outlet flow direction (22) of the fluid from the angle piece (10) form limbs of the alteration angle (24), characterized in that at least one guide element (30) is arranged in the channel portion (12), which guide element protrudes into the channel portion (12), the at least one guide element (30) altering the flow direction of a part of the fluid by the alteration angle (24). The angle piece (10) thus has a low pressure drop.
Patent CA-3125118-A1 (CA)
Inventor: MOORE LEVI
IPC: H01Q1/42
Filed: 2019-12-12
Abstract: La présente invention concerne une structure de radôme qui peut comprendre un composant de couche d'accord interne et un composant stratifié recouvrant le composant de couche d'accord interne. Le composant de couche d'accord interne peut comprendre une mousse thermodurcie ou une mousse thermoplastique. Le composant stratifié peut comprendre une première couche diélectrique renforcée par des fibres, une deuxième couche diélectrique renforcée par des fibres recouvrant la première couche diélectrique renforcée par des fibres, et une troisième couche diélectrique renforcée par des fibres recouvrant la deuxième couche diélectrique renforcée par des fibres. La première couche diélectrique renforcée par des fibres peut comprendre un premier matériau à faible constante diélectrique. La deuxième couche diélectrique renforcée par des fibres peut comprendre un premier matériau à constante diélectrique élevée. La troisième couche diélectrique renforcée par des fibres peut comprendre un second matériau à faible constante diélectrique.
Patent CA-3125533-A1 (CA)
Title: Conjugates of pattern recognition receptor agonists
Inventor: SPROGOE KENNETT
IPC: A61K47/64
Filed: 2020-01-03
Abstract: The present invention relates to a conjugate or its pharmaceutically acceptable salt, wherein said conjugate is water-insoluble and comprises a carrier moiety Z to which one or more moieties -L2-L1-D are conjugated, wherein each -L2- is individually a chemical bond or a spacer moiety; each -L1- is individually a linker moiety to which -D is reversibly and covalently conjugated; and each -D is individually a pattern recognition receptor agonist. It further relates to pharmaceutical compositions comprising such conjugate and to their use in the treatment of cell-proliferation disorders; and to related aspects.
Patent CA-3129228-A1 (CA)
Title: Markers for the diagnosis of biochemical recurrence in prostate cancer
Inventor: KIEBISH MICHAEL ANDREW
IPC: G01N33/574
Filed: 2020-02-06
Abstract: Methods for diagnosing the presence of BCR in prostate cancer in a subject are provided, such methods including the detection of levels of a variety of biomarkers diagnostic of BCR. Compositions in the form of kits and panels of reagents for detecting the biomarkers of the invention are also provided.
Patent CA-3129837-A1 (CA)
Title: Paper coating composition containing high starch levels
Inventor: FOGG JAMES
IPC: D21H21/18
Filed: 2020-02-20
Abstract: Described herein is coating starch composition comprising a starch and a plasticizer, as well as a paper coating composition comprising said coating starch composition, where the paper coating composition contains at least 2% starch, a dry solids content of at least 40%, and a viscosity of less than about 1200 cPs, as well as methods of using and making such compositions, such as, for example, in paper manufacturing processes.
Patent CA-3130420-A1 (CA)
Title: Casque
Inventor: POMERING AMY
IPC: A42B3/06
Filed: 2017-12-12
Abstract: Selon un aspect de la présente invention, un casque comprend une coquille intérieure (3), une coquille extérieure détachable (2) et une couche intermédiaire (4) entre la coquille intérieure et la coquille extérieure. Au moins un élément de connexion (5) est configuré pour raccorder directement la coquille intérieure à la coquille extérieure et permet le glissement entre les deux coquilles lorsque la coquille extérieure est attachée au casque. Lorsquelle est ainsi attachée, la coquille extérieure et la coquille intérieure sont configurées pour glisser lune par rapport à lautre en réponse à un choc. Une interface de glissement est fournie entre la couche intermédiaire et lune ou les deux coquilles extérieure et intérieure.
Patent CA-3133395-A1 (CA)
Inventor: BARNTHOUSE KRISTOPHER
IPC: A61K47/64
Filed: 2020-03-12
Abstract: Methods of manufacture for producing anti-IL-12/IL-23p40 antibodies, e.g., the anti-IL-12/IL-23p40 antibody ustekinumab, in CHO and specific pharmaceutical compositions of the antibody are useful in treating various diseases.
Patent CA-3133655-A1 (CA)
Inventor: EVANS JAMES FREDERICK
IPC: B23K11/00
Filed: 2020-04-03
Abstract: An apparatus for use in a continuous welding system including a welding head configured to remain stationary relative to translating steel sheets or plates. The apparatus includes a hollow elongate body and a port. The body extends between two closed ends. The port is coupled to a non-oxidizing gas source and in communication with the body. The body defines a plurality of openings. The openings are configured to direct non-oxidizing gas towards the steel sheets or plates to simultaneously shield a weld formed by the welding head from atmosphere and cool the weld.
Patent CA-3134616-A1 (CA)
Inventor: JIBAJA HANK
IPC: H04L69/14
Filed: 2020-03-20
Abstract: Methods and systems are provided to generate and obtain data from mobile medical devices such as nebulizers and mobile monitors such as pacemakers and to store provenance parameters for the data in a distributed ledger for use in verifying the source and accuracy of the data. The methods and systems may further be used to reduce readmittance rates at healthcare facilities.
Patent CA-3137683-A1 (CA)
Inventor: DECHASSEY EMMANUEL
IPC: B22D7/00
Filed: 2020-05-12
Abstract: L'invention concerne un lingot, ayant un volume compris entre 0,15 m3 et 0,80 m3 et un rapport surface sur volume compris entre 10 m-1 et 18 m-1, constitué d'au moins un métal, ayant des faces longitudinales s'étendant entre deux faces d'extrémité et comprenant au moins un trou s'étendant à partir d'une desdites faces longitudinales, la distance maximale entre n'importe quel point de la périphérie de trou, jusqu'à sa face longitudinale la plus proche, étant notée MaxL, ledit au moins un trou étant conçu de telle sorte que ladite distance maximale MaxL soit inférieure à la distance minimale, notée MinE, entre n'importe quel point de la périphérie de trou et sa face d'extrémité la plus proche.