baber/WOPTO huggingface dataset:
Patent AU-2020316335-A1 (AU)
Title: Multilamellar RNA nanoparticles
Inventor: SAYOUR ELIAS
IPC: A61K9/127
Filed: 2020-07-17
Abstract: The present disclosure provides a nanoparticle comprising a positively-charged surface and an interior comprising (i) a core and (ii) at least two nucleic acid layers, wherein each nucleic acid layer is positioned between a cationic lipid bilayer. Methods of making such nanoparticles are further provided herein. Additionally, related cells, populations of cells, pharmaceutical compositions comprising the presently disclosed nanoparticles are provided. Methods of increasing an immune response against a tumor in a subject, methods of delivering RNA molecules to an intra-tumoral microenvironment, lymph node, and/or a reticuloendothelial organ in a subject, and methods of treating a subject with a disease are furthermore provided.
Patent AU-2020350221-A1 (AU)
Title: Combination cancer therapy and cytokine control therapy for cancer treatment
Inventor: NOVIK SHAI
IPC: C07K19/00
Filed: 2020-09-16
Abstract: Compositions disclosed herein, and methods of use thereof included those for inhibiting or reducing the incidence of cytokine release syndrome or cytokine storm in a subject undergoing CAR T-cell therapy, methods of treating a cancer or tumor, methods of reducing tumor load, methods of reducing the size or growth rate of a cancer or a tumor, and methods of extending of the survival of a subject suffering from a cancer or tumor, wherein the subjects are administered compositions comprising apoptotic cells or apoptotic cell supernatants. Compositions and methods of use thereof may increase the efficacy of a CAR T-cell cancer therapy. Disclosed herein are also methods for slowing, reducing, inhibiting, or eliminating metastatic spread of a cancer or a tumor in a subject, comprising administering a combination therapy comprising an early apoptotic cell population and one or more cancer therapeutic agents.
Patent AU-2020363903-A1 (AU)
Title: Prodrugs of myeloperoxidase inhibitors
Inventor: DUBOWCHIK GENE M
IPC: C07D487/04
Filed: 2020-10-09
Abstract: Disclosed are prodrugs of myeloperoxidase (MPO) inhibitors, methods of treating MPO related disorders, e.g., multiple system atrophy, amyotrophic lateral sclerosis, and Huntingtons disease, and methods of neuroprotection, which include administering to a patient in need thereof the prodrugs, pharmaceutical compositions including the prodrugs, and kits including the pharmaceutical compositions and instructions for use.
Patent AU-2020370874-A1 (AU)
Title: Continuous or periodical transdermal delivery of exogenous molecule
Inventor: ESSALIK ABDELTIF
IPC: A61K9/00
Filed: 2020-12-03
Abstract: It is provided a method and device for delivering transdermally a molecule non-invasively to a subject comprising irreversibly electroporating a region of the skin.
Patent AU-2020372333-A1 (AU)
Title: Methods for treating a hematological cancer and the use of companion biomarkers for 2-(2,6-Dioxopiperidin-3-yl)-4-((2-fluoro-4-((3-morpholinoazetidin-1-yl)methyl)benzyl)amino)isoindoline-1,3-dione
Inventor: ANTON MARIA SORAYA CARRANCIO
IPC: A61P35/00
Filed: 2020-10-20
Abstract: A method of identifying a subject having a hematological cancer who is likely to be responsive to a treatment compound, comprising administering the treatment compound to the subject having the hematological cancer; obtaining a sample from the subject; determining the level of a biomarker in the sample from the subject; and diagnosing the subject as being likely to be responsive to the treatment compound if the level of the biomarker in the sample of the subject changes as compared to a reference level of the biomarker; wherein the treatment compound is Compound 1, Compound 2, or Compound 3.
Patent AU-2020389892-A1 (AU)
Title: Pneumatic hydraulic safety system
Inventor: SHI FENG
IPC: F15B13/06
Filed: 2020-07-14
Abstract: A pneumatic hydraulic safety system, comprising an air storage tank (4), a pressure switch (9), a two-position two-way switching valve (10), a three-position five-way reversing valve (11), a shuttle valve (12), a two-position two-way pneumatic control valve (13), a pneumatic motor (15), a hydraulic pump (18), an oil tank (27), a pneumatic control hydraulic valve (22), and a hydraulic cylinder (25.1, 25.2). By means of coordination of the three-position five-way reversing valve (11), the shuttle valve (12), the two-position two-way pneumatic control valve (13), and the pneumatic control hydraulic valve (22), the pneumatic motor (15) is in a stop or start state, and thus expansion or contraction of the hydraulic cylinder (25.1, 25.2) is enabled according to requirements, so that safe operation can be ensured, noise is reduced, the problem of energy waste is solved, and good practicability is achieved because expansion and contraction of the hydraulic cylinder can be switched according to requirements.
Patent WO-2021168513-A1 (WO)
Inventor: MELLOS HEIDI
IPC: A61F13/511
Filed: 2021-02-26
Abstract: A protective garment, gussets for protective garments, and individual gusset layers, being a moisture wicking layer, a core moisture absorbing layer and a moisture impermeable layer, and combinations thereof. The moisture wicking layer including a double knit fabric wherein a technical face of the fabric forms an eyelet mesh utilising both hydrophilic and hydrophobic yams and a technical back of the fabric forms an interlock utilising only hydrophilic yams. The moisture absorbing layer including a sinker terry fabric knit comprising sinker loops with plush loops made form synthetic fibres treated with a hydrolysing enzyme that splits the fibres into fibrils. The moisture impermeable layer including a base fabric knit laminated with a polyurethane sheet.
Patent AU-2021201661-A1 (AU)
Title: Systems and methods for determining path confidence for unmanned vehicles
Inventor: SCHUBERT Martin Friedrich
IPC: G05D1/12
Filed: 2021-03-16
Abstract: SYSTEMS AND METHODS FOR DETERMINING PATH CONFIDENCE FOR 
UNMANNED VEHICLES 
ABSTRACT 
Examples implementations relate to determining path confidence for a vehicle. An 
example method includes receiving a request for a vehicle to navigate a target location. The 
method further includes determining a navigation path for the vehicle to traverse a first segment 
of the target location based on a plurality of prior navigation paths previously determined for 
traversal of segments similar to the first segment of the target location. The method also 
includes determining a confidence level associated with the navigation path. Based on the 
determined confidence level, the method additionally includes selecting a navigation mode for 
the vehicle from a plurality ofnavigation modes corresponding to a plurality of levels of remote 
assistance. The method further includes causing the vehicle to traverse the first segment of the 
target location using a level of remote assistance corresponding to the selected navigation mode 
for the vehicle.
Patent AU-2021202007-A1 (AU)
Title: Anticipatory dispatch of UAVs to pre-staging locations
Inventor: BLAKE JESSE
IPC: G06Q10/06
Filed: 2021-03-31
Abstract: ANTICIPATORY DISPATCH OF UAVS TO PRE-STAGING LOCATIONS 
ABSTRACT 
An example method involves determiningan expected demand level fbr a first type of 
a plurality of types of transport tasks for unmanned aerial vehicles (UAVs), the first type of 
transport tasks associated with a first payload type. Each of the UAVs is physically 
reconfigurable between at least a first and a second configuration corresponding to the first 
payload type and a second payload type, respectively. The method also involves detemining 
based on the expected demand level for the first type of transport tasks, (i) a first number of 
JAVs having the first configuration and (ii) a second number of UAVshavingthesecond 
configuration. The method further involves, at or near a time corresponding to the expected 
demand level, providing one or more UAVs to perform the transport tasks, including at least 
the first number of UAVs,
Patent AU-2021202032-A1 (AU)
Title: Substituted picolinic acids and pyrimidine-4-carboxylic acids, method for the production thereof, and use thereof as herbicides and plant growth regulators
Inventor: GERHARD HOFFMANN MICHAEL
IPC: A01N43/40
Filed: 2021-04-01
Abstract: SUBSTITUTED PICOLINIC ACIDS AND PYRIMIDINE-4-CARBOXYLIC ACIDS, 
METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS 
HERBICIDES AND PLANT GROWTH REGULATORS 
3 4 
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R
2 
x 
A N COOR 
The invention relates to a carboxylic acid derivatives of benzoheterocyclyl pyridines and 
benzoheterocyclyl pyrimidines of general formula (1) and to the use thereof as 
herbicides. (1) In said formula (1), X stands for N or CH, A stands for a benzo-fused 
heterocycle, and R', R2, R3, and R4 stand for groups such as hydrogen and organic 
groups such as alkyl.
Patent AU-2021203186-A1 (AU)
Title: Work area monitoring system and method of operating a work vehicle at a work area
Inventor: JONES AMY K
IPC: G08G1/16
Filed: 2021-05-18
Abstract: A method of operating a work vehicle at a work area and a work area monitoring system for a 
work vehicle are provided. The method includes monitoring a target area in the work area and 
activating a response on the work vehicle directed toward the target area upon satisfaction of a 
work area condition in the work area.  
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Patent AU-2021203256-A1 (AU)
Title: Preparation and composition of medium chain triglycerides containing substantial amount of lauric acid
Inventor: LAO JR DEAN A
IPC: C11C1/00
Filed: 2021-05-20
Abstract: DCC-20/05/2021 
ABSTRACT 
The present invention pertains to an efficient and large-scale process to produce a 
medium-chain triglyceride composition with >95% content for C8 (caprylic acid), C10 
(capric acid) and C12 (lauric acid), with the content of lauric acid at about 5% or more. The 
5 process involves fractionation of fatty acid methyl esters, which are mainly derived from 
coconut or palm kernel, their esterification to glycerol to synthesize medium-chain 
triglycerides, and refining them to significantly increase purity and make them fit for human 
consumption. Such composition can have important uses in food and its preparation, health 
supplements, cosmetics, and medicine, among others.
Patent AU-2021204079-A1 (AU)
Title: Novel peptides and combination of peptides for use in immunotherapy against various tumors
Inventor: MAHR ANDREA
IPC: C07K14/47
Filed: 2021-06-18
Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in 
immunotherapeutic methods. In particular, the present invention relates to the 
immunotherapy of cancer. The present invention furthermore relates to tumor
associated T-cell peptide epitopes, alone or in combination with other tumor
associated peptides that can for example serve as active pharmaceutical ingredients 
of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate 
T cells ex vivo and transfer into patients. Peptides bound to molecules of the major 
histocompatibility complex (MHC), or peptides as such, can also be targets of 
antibodies, soluble T-cell receptors, and other binding molecules.
Patent AU-2021204624-A1 (AU)
Title: System and method for preparing a pharmaceutical compound
Inventor: SANDMANN CHRISTIAN
IPC: G06V30/224
Filed: 2021-07-01
Abstract: A system for preparing a pharmaceutical compound comprises: a computing 
device comprising a user interface providing an operator with instructions for preparing the 
pharmaceutical compound and at least one processor operatively connected to the user 
interface; a scale operatively connected to the at least one processor; and an image capture 
device operatively connected to the at least one processor and the scale and positioned to 
capture an image of at least one of a component used in preparing the pharmaceutical 
compound and the pharmaceutical compound.  
- 1 -
Patent AU-2021205156-A1 (AU)
Title: Tricyclic tetrahydroisoquinoline derivative, preparation method therefor and application thereof in medicine
Inventor: YANG FANGLONG
IPC: A61P25/28
Filed: 2021-01-08
Abstract: The present disclosure relates to a tricyclic tetrahydroisoquinoline derivative, a preparation method therefor and an application thereof in medicine. In particular, the present disclosure relates to a tricyclic tetrahydroisoquinoline derivative represented by general formula (I), a preparation method therefor and a pharmaceutical composition comprising said derivative, a use thereof as an estrogen receptor modulator, and a use thereof in preparing a drug for treating estrogen receptor-mediated or dependent diseases or disorders. The substituents in general formula (I) are the same as those defined in the description.
Patent AU-2021213088-A1 (AU)
Title: Kit, system, and flow cell
Inventor: CHEN TYLER
IPC: C12N15/10
Filed: 2021-01-25
Abstract: An example of a kit includes a library preparation fluid, a sample fluid, and an enrichment fluid. The library preparation fluid includes library preparation beads, where each library preparation bead includes a first solid support, and a transposome attached to the first solid support. The fluid includes a genomic deoxyribonucleic acid sequence. The enrichment fluid includes target capture beads, where each target capture bead includes a second solid support, and capture probes attached to the second solid support. Each of the capture probes includes a single stranded deoxyribonucleic acid sequence that is complementary to a targeted region of the genomic deoxyribonucleic acid in the sample fluid.
Patent AU-2021221390-A1 (AU)
Title: A security system
Inventor: SZRENKO MARK
IPC: G08B3/10
Filed: 2021-08-23
Abstract: t-IZI -RUU 
ABSTRACT 
A security system comprising a padlock 1; a detect and transmit system 3 
configured to detect tampering with the padlock and in response thereto wirelessly 
transmit a signal; and a wearable device 5 configured to alarm in response to the 
5 signal to alert a wearer to the tampering.
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Patent AU-2021226497-A1 (AU)
Title: Medical systems, devices, and related methods
Inventor: LYDECKER LAUREN
IPC: A61M1/00
Filed: 2021-02-19
Abstract: A medical system includes a source of a material, a first tube, and a second tube. The material is configured to expand and form a porous body after the material is deployed into a body lumen. The first tube is configured to deliver the material into the body lumen, and the second tube is configured to apply suction to the porous body.
Patent AU-2021237840-A1 (AU)
Title: A system and method for pyrolysis of plastics
Inventor: AZULY AMIT
IPC: C10B7/10
Filed: 2021-03-15
Abstract: A continuous pyrolysis system including a pyrolysis chamber, a heating chamber, a feeding chamber having a pressure input, an output coupled to the pyrolysis chamber, and a feeding opening opened to ambient atmosphere, a flame injector injecting ambient air and combustible material into the heating chamber, a pumping device with an input coupled to the heating chamber, and an output coupled to the pressure input of the feeding chamber, a O
Patent AU-2021240432-A1 (AU)
Title: Defective interfering viral genomes
Inventor: VIGNUZZI MARCO
IPC: A61K39/00
Filed: 2021-03-26
Abstract: Method for producing a defective interfering viral genome (DVG), defective interfering particles comprising the DVG, and methods and uses thereof.
Patent AU-2021275471-A1 (AU)
Title: Autoinjector housing
Inventor: PETIT LOUIS
IPC: A61M5/50
Filed: 2021-05-19
Abstract: Provided herein is a housing assembly for a drug delivery device, including a first housing part having a first proximal end comprising a first engagement portion and a second engagement portion, a first distal end, and a first sidewall therebetween defining a first longitudinal axis and a first interior, the first sidewall comprising one or more windows therethrough; and a second housing part having a second proximal end, a second distal end comprising a third engagement portion and a fourth engagement portion, and a second sidewall therebetween defining a second longitudinal axis and a second interior.
Patent AU-2021292539-A1 (AU)
Title: ADAS comprising bacterial secretion systems
Inventor: TAM HOK HEI
IPC: C12N1/08
Filed: 2021-06-17
Abstract: The invention provides isolated achromosomal dynamic active systems (ADAS), including ADAS comprising secretion systems. These ADAS provided by the invention can be obtained by a variety of means. Various associated methods of making and using these ADAS are provided.
Patent AU-2021297778-A1 (AU)
Title: Compounds for targeted degradation of interleukin-2-inducible T-cell kinase and methods of use
Inventor: GRAY NATHANAEL S
IPC: A61K31/436
Filed: 2021-06-22
Abstract: Disclosed are bispecific compounds (degraders) that target ITK or a zinc finger (ZnF) protein for degradation. Also disclosed are pharmaceutical compositions containing the degraders and methods of using the compounds to treat diseases and disorders characterized or mediated by ITK or ZnF protein activity.
Patent AU-2021330125-A1 (AU)
Title: Beer-flavored beverage
Inventor: OKAJIMA TAKAHO
IPC: C12C5/02
Filed: 2021-03-30
Abstract: Provided is a beer-flavored beverage containing: 4-vinylguaiacol in an amount of 1000 ppb by mass or less; ethyl n-butyrate in an amount of 140 ppb by mass or more; and at least one lactone selected from γ-decalactone and γ-undecalactone. The ratio between the content of ethyl n-butyrate (unit: ppb by mass) and the total content of the lactone (unit: ppb by mass) [ethyl n-butyrate/the lactone] is 1100 or less.
Patent AU-2021343194-A1 (AU)
Title: Method of thrombus removal and related devices and systems
Inventor: MCLAUGHLIN ROBERT
IPC: A61F2/06
Filed: 2021-09-14
Abstract: A vascular access instrument configured to insert through a vascular access device. The vascular access instrument may include a wire, which may include a proximal end and a distal end opposite the proximal end. The distal end may include a bent shape, which may facilitate removal of a thrombus. The bent shape may include a looped portion. The bent shape may include a S-shaped portion proximate a U-shaped portion. The bent shape may include a spiral. The instrument advancement device may be configured to advance the vascular access instrument from a retracted position within a catheter assembly to an advanced position beyond a distal end of the catheter. The vascular access instrument may include an intraluminal layer, which may bend from an inner portion of the catheter to an outer surface of the catheter around an edge of the catheter forming a distal opening of the catheter.
Patent AU-2021346845-A1 (AU)
Title: Casing for protecting food and beverages products, casing blank and method for manufacturing such casing from the casing blank
Inventor: GUILLAUD-BATAILLE JEAN-CHRISTOPHE
IPC: B65D75/42
Filed: 2021-09-23
Abstract: Casing (1000) for transporting food or beverage product, comprising a side panel part (1200) comprising at least two side panels (1201, 1202), each side panel comprising a peripheral free edge (1211, 1212) and a sealing margin (1221, 1222) along the peripheral free edge, and one band (1100), made from one sheet, and comprising a sealing area which is sealed to the sealing margin (1221, 1222) of both side panels, forming a flange (1300) extending outward. Blank for forming such casing and method for manufacturing such casing.
Patent AU-2021347156-A1 (AU)
Title: Efficient and manufacturable mechanical computing
Inventor: RYLEY III JAMES F
IPC: H03K19/02
Filed: 2021-09-22
Abstract: Logic mechanisms operate to define the position of at least one mechanical output based on the position of two or more mechanical inputs, and employ at least one control element that functions to determine (at least in part) whether an output is moved, and which provides the same function in more than one position. Some mechanisms are configured to determine, based on the input positions, whether a path to transmit motion to an output exists or does not exist. Some mechanisms are configured to determine, based on the input positions, whether or not motion of a driven element can be accommodated without moving an output.
Patent AU-2021361693-A1 (AU)
Title: Systems and methods for detection and tracking of unmanned aerial systems
Inventor: LEE EUGENE
IPC: G08G5/00
Filed: 2021-07-08
Abstract: Radar systems and methods detecting and tracking an unmanned aerial system (UAS) are provided. The radar system and methods can include determining whether or not a UAS is included in the plurality of electromagnetic signals received by the radar system based on one or more expected frequencies that one or more UAS devices use to transmit signals to remote controls. The radar systems and method can also involve switching the radar system into a track mode upon detecting a UAS.
Patent AU-2021391432-A1 (AU)
Title: Cassette for retention of fluid path components for fluid injector system
Inventor: NAPLES ANDREW
IPC: A61M5/14
Filed: 2021-11-30
Abstract: A cassette for holding fluid path components for a fluid injector may include a body defining at least one feature for holding at least one fluid path component for the fluid injector; and a connecting member for removably connecting the body of the cassette to the fluid injector, the connecting member operatively connected to the body, wherein the connecting member comprises at least one pivotable connecting feature protruding from the body, and wherein each of the at least one pivotable connecting feature is configured for removably connecting to a corresponding connecting feature receiver on the fluid injector such that the body is pivotally movable relative to the fluid injector between a first, unlatched position and a second, latched position in which the at least one fluid path component on the body of the cassette is positioned for operative connection to a corresponding feature of the fluid injector.
Patent AU-2021451772-A1 (AU)
Title: Ammonia cracking process
Inventor: SHAW ANDREW
IPC: C01B3/04
Filed: 2021-06-18
Abstract: Ammonia cracking process in which cracked gas is purified in a PSA system are improved by converting residual ammonia in the first cracked gas into further hydrogen and nitrogen by feeding PSA tail gas, or a gas derived therefrom, to a secondary cracking reactor and further processing the second cracked gas.
Patent AU-2022200839-A1 (AU)
Title: Safety corridor arrangement
Inventor: LEWIS MITCHELL
IPC: G09F27/00
Filed: 2022-02-09
Abstract: The invention relates to a safety corridor arrangement for use in emergency situations, 
including an activation means, an operation means, associated with an activation centre, 
and a safety corridor suitable to guide or direct a person on a particular pathway. The 
activation centre, through activation of the activation means can cause operation of the 
operation means, and the operation means creates the safety corridor to guide a person 
along the safety corridor towards an exit. The invention also relates to a point of exit 
arrangement, and methods of use.