baber/WOPTO huggingface dataset:
Patent DE-69433747-D1 (DE)
Inventor: LI YI
IPC: C12N5/06
Filed: 1994-08-16
Granted: 2004-06-03
Abstract: A human CGRP receptor polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for identifying antagonists and agonists to such polypeptide. Antagonists against such polypeptides may be used therapeutically to treat cancer, arthrits, pain, diabetes, migraine and inflammation and agonists which may be used to treat hypercalcemia, obesity, hypertension, and disorders of bone remodelling. Diagnostic assays are also disclosed which detect the presence of mutations in the nucleic acid sequences which encode the receptor polypeptide.
Patent DE-69435285-D1 (DE)
Inventor: MARCATO FORREST C
IPC: E01C23/16
Filed: 1994-01-14
Granted: 2010-05-06
Abstract: A method and apparatus for applying a traffic stripe (10) having improved reflectivity includes a vehicle having an apparatus (50) for applying the traffic stripe, an applying assembly (52) for dispensing a reflective material over the traffic stripe, another applying apparatus (66) for applying an anti-adhesion agent, and a deformation apparatus (64) disposed rearward thereof for forming interval grooves in the traffic stripe. The application of the anti-adhesion agent directly onto the traffic stripe or onto the deformation apparatus prevents the freshly applied traffics tripe from lifting off the road surface and adhering to the deformation apparatus. <IMAGE>
Patent DE-69517092-D1 (DE)
Inventor: MIHM JOSEPH J
IPC: B60R21/26
Filed: 1995-06-12
Granted: 2000-06-29
Abstract: An air-bag module (10) comprises an inflatable vehicle occupant restraint (12), an inflator (18) having first and second axial end walls (64, 66), and a diffuser (20) having first and second end walls (90, 92). A chamber (94) extends between the first and second end walls (90, 92) of the diffuser (20). The first axial end wall (64) of the inflator (18) is supported in the chamber (94) at the first end wall (90) of the diffuser (20), and the second axial end wall (66) of the inflator (18) is supported in the chamber (94) at the second end wall (92) of the diffuser (20). The module (10) further includes an end cap (26) which is fastened to the first end wall (90) of the diffuser (20) in a fastened position. The end cap (26) imparts an axially directed supporting force to the inflator (18). The supporting force urges the inflator (18) axially inward of the chamber (94) at the first end wall (90) of the diffuser (20), and urges the inflator (18) axially outward of the chamber (94) at the second end wall (92) of the diffuser (20).
Patent DE-69517435-D1 (DE)
Inventor: REINDERS ANTONIUS
IPC: B32B27/08
Filed: 1995-09-22
Granted: 2000-07-13
Abstract: PCT No. PCT/NL95/00318 Sec. 371 Date Jun. 2, 1997 Sec. 102(e) Date Jun. 2, 1997 PCT Filed Sep. 22, 1995 PCT Pub. No. WO96/09928 PCT Pub. Date Apr. 4, 1996The invention provides a light-transmitting cover foil intended to be arranged adheringly to a surface, for instance the surface of a carrier plate, optionally bearing information such as letters, numbers, images or the like, which foil consists of a laminate comprising: a first layer plastically deformable only at a relatively high first temperature, for instance in the range of 120 DEG  C.-200 DEG  C. and comprising for instance polycarbonate, PMMA, PVC, ABS, PP, PE, which first layer is provided before, during or after joining together to the other layers with a structure, for instance a texture and/or pattern pressed out of its main surface by exerting pressure and increasing temperature to at least the said first temperature, for instance by applying a heated profile roller; a second layer adhered thereto consisting of a dimensionally stable carrier layer comprising for instance polycarbonate, PMMA, PVC, polyester/PET, ABS; and a third layer adhered thereto which is meltable and thus thermally-activated at a relatively low second temperature, for instance in the range of 50 DEG  C.-90 DEG  C. and which consists of a hot-melt layer or glue layer, comprising for instance EVA, EEA, EBA, EMA, GBA or other low-melting plastics including polyolefins and copolymer esters, polyacetate esters, softened PVCs; which said layers are mutually connected by adhesive agents, for instance by making use of coextrusion.
Patent DE-69521276-D1 (DE)
Inventor: BELLUS JACQUES
IPC: C21D1/20
Filed: 1995-12-07
Granted: 2001-07-19
Abstract: Micro-alloyed steel consists of (in wt%): 0.05-0.5 C; 1-2 Mn; 0.05-1.55 Si; 0.1-1 Cr; 0-0.5 Mo; 0-0.3 V; 0-0.01 B; 0-0.03 Ti; and 0-0.1Nb. It has a bainitic structure. A blank of the steel is subjected to surface heat treatment by laser beam, induction heating or electron bombardment, followed by quenching. The heat affected zones are heated to 500-900 degrees C and cooled at a rate of above 500 degrees C/hr..
Patent DE-69527748-D1 (DE)
Inventor: POURPRIX MICHEL
IPC: G01N15/02
Filed: 1995-05-22
Granted: 2002-09-19
Abstract: The spectrometer includes an electrical mobility selector which consists of two concentric discs (18,20). One of the discs (18) presents a circular slit (22) through which an aerosol to be analysed enters the appts. A central suction tube (26) extracts a gas sample from the space between the discs. The discs are conductor and connected to a power source thus generating an electric field (E). A similar circular slit (28) is provided on the second disc (20). A jet of filtered air is injected in the space delimited by the two discs. A mechanical collector 917) traps particles with electrical mobility equal to an adjustable threshold value (Z). <IMAGE>
Patent DE-69531051-D1 (DE)
Inventor: CHAO CHIEN-CHUNG
IPC: B01J20/18
Filed: 1995-09-04
Granted: 2003-07-17
Abstract: In using calcium-exchanged forms of zeolite X as selective adsorbents for nitrogen in PSA air separation process, it has been discovered that, particularly under certain temperature and pressure conditions, superior performance is not, as is generally believed, obtained when the calcium content is at a maximum, but rather when the degree of calcium exchange is in the range of 60 to 89 equivalent percent and only when the framework Si/Al2 ratio of the zeolite is within the range of 2.0 to 2.4
Patent DE-69531902-D1 (DE)
Inventor: EMBLETON JONATHAN KENNETH
IPC: A61J1/05
Filed: 1995-08-30
Granted: 2003-11-13
Abstract: A unit container for a treatment fluid comprises a sealed enclosure of which one wall section thereof is formed with at least one opening. The enclosure is pressuriseable to discharge its contents through the opening or openings, which is or are of sufficient diameter to enable the generation of a jet and/or discrete droplets of treatment fluid discharged therefrom. The one wall section is typically a flat section of the enclosure wall, and the enclosure is typically a blister pack, with the wall section at a planar base of the blister. However, the one wall section may be dome shaped and formed with at least one opening in the top region of the dome. Containers of the invention may be provided in packages, for example in strip form or in planar arrays. Dispensing devices are described for discharging their contents in treatment.
Patent DE-69532187-D1 (DE)
Inventor: MANTEGANI SERGIO
IPC: A61K31/40
Filed: 1995-04-13
Granted: 2004-01-08
Abstract: There are provided compounds of formula (I), wherein R1 is a hydrogen, chlorine or bromine atom or a methyl, methylthio, hydroxy, cyano or carboxamido group; R2 is C1-C3 alkyl or an alkyl group; R3 and R4 are independently a hydrogen atom, a C1-C5 alkyl group, a C3-C5 alkenyl group, a C5-C6 cycloalkyl C1-C3 alkyl group, a phenyl-C3-C5 alkenyl or phenyl group: which groups are optionally substituted by C1-C3 alkyl, C1-C3 alkoxy, triflouromethyl, hydroxy or amino group; or a group of formula (a), wherein R6 is hydrogen atom or a C1-C3 alkyl group and R7 is a phenyl group, a substituted phenyl group as described above or a heterocyclic ring, R5 is a hydrogen or bromine atom or an organic residue and R is H or an organic residue, or a pharmaceutically acceptable salt thereof. A process for their preparation and the pharmaceutical compositions comprising them are also provided.
Patent DE-69535733-D1 (DE)
Inventor: SCHUELEIN MARTIN
IPC: D21C9/10
Filed: 1995-10-06
Granted: 2008-04-24
Abstract: An enzyme composition with substantial cellulolytic, especially endoglucanase, activity at alkaline conditions which is derived from or producible by fungi from the genus  Acremonium,  e.g. derivable from or produced by  Acremonium sp., Acremonium persicinum, Acremonium acremonium, Cephalosporium sp., Acremonium brachypenium, Acremonium dichromosporum, Acremonium obclavatum, Acremonium pinkertoniae, Acremonium roseogriseum, Acremonium incoloratum,  and  Acremonium furatum,  provided that the enzyme composition is not immunologically cross-reactive with antibodies raised against endoglucanases (EC 3.2.1.4) from  Humicola insolens,  DSM 1800,  Fusarium oxysporum,  DSM 2672,  Myceliophthora thermophila,  CBS 117.65, or  Cephalosporium sp.,  RYM-202; and a DNA construct comprising a DNA sequence encoding an enzyme exhibiting endoglucanase activity, the enzyme composition or recombinant enzyme being useful e.g. for providing localised variation in the colour density of dyed fabric such as stone-washing of denim, for improving the drainage of an aqueous suspension of paper pulp, for the deinking of recycled paper, in detergent compositions and in fabric softeners.
Patent DE-69535902-D1 (DE)
Inventor: BENOIST CHRISTOPHE O
IPC: A01K67/027
Filed: 1995-05-18
Granted: 2009-02-26
Abstract: A transgenic animal model for arthritis is disclosed. The arthritic condition results from genetic (or immunologic) manipulations that result in the T cell receptor (TCR) repertoire of the animal being substantially limited relative to the TCR repertoire of a wildtype control animal. The TCR repertoire of the arthritic animal, albeit limited, is functionally viable. In a preferred embodiment, the invention relates to transgenic arthritic mice wherein arthritis results from (1) a transgenic allele which encodes and expresses TCR  alpha  and  beta  subunits that combine in T lymphocytes of the transgenic animal to form a TCR that recognizes an antigen comprising one or more epitopes of an oligopeptide derived from amino acids 41-61 of bovine pancreatic ribonuclease and/or (2) polypeptide arthritogenic self antigens derived from endogenous proteins. The transgenic arthritic mice of the invention provides an animal model which faithfully mimics rheumatoid arthritis and by which human arthritogenic and therapeutic anti-arthritic compositions are evaluated. Also provided herein are therapeutic oligopeptides derived from the variable regions of the TCRs of the transgenes of the invention and/or from the amino acid sequence of proteins comprising endogenous polypeptide arthritogenic antigens.
Patent DE-69607105-D1 (DE)
Inventor: VATTEMENT HUBERT
IPC: C04B14/26
Filed: 1996-11-14
Granted: 2000-04-20
Abstract: A high thermal conductivity grout, esp. for injection into buried conduits containing high voltage lines, comprises a mixture of cement, water, bentonite and dolomite, the novelty being that the dolomite consists mainly of particles of less than 50 microns size. Pref. the weight of dolomite in the mixture is at least equal to the weight of water. Also claimed is a method of preparing the above grout.
Patent DE-69620011-D1 (DE)
Inventor: UCHIYAMA HIROTAKA
IPC: A61K8/891
Filed: 1996-10-16
Granted: 2002-04-25
Abstract: The present invention relates to conditioning shampoo compositions having improved stability and conditioning benefits. These compositions comprise a surfactant system further comprising a detersive anionic surfactant and a stabilizing surfactant; a fatty compound selected from the group consisting of fatty alcohols, fatty acids, fatty alcohol derivatives, fatty acid derivatives, and mixtures thereof; a hair conditioning agent selected from the group consisting of nonvolatile dispersed silicone conditioning agents, hydrocarbon conditioning agents, water soluble cationic polymeric conditioning agents, and mixtures thereof, and water. The present invention also relates to methods for cleansing and conditioning the hair.
Patent DE-69623652-D1 (DE)
Inventor: WALSH DESMOND
IPC: A61K47/24
Filed: 1996-06-20
Granted: 2002-10-17
Abstract: A pharmaceutical and/or veterinary formulation comprising deslorelin and an excipient, the formulation being characterised in that, in vitro, it releases deslorelin into phosphate buffered saline, as hereinbefore described, at 37° C. at a rate of about 2-80 mug/day for at least 200 days. The formulation may be used for prevention of reproductive function, particularly in dogs and cats, and for the treatment, particularly in humans, of prostate and breast cancer and other diseases and conditions where suppression of testosterone or estradiol levels is beneficial.
Patent DE-69629204-D1 (DE)
Inventor: PARKER A
IPC: A61F5/01
Filed: 1996-10-25
Granted: 2003-08-28
Abstract: An ankle brace product including an ankle brace for being custom-formed to the shape of an ankle while flexible and upon hardening providing a rigid, supporting custom fit. The ankle brace product includes an outer container formed of moisture-impervious material and a flexible ankle brace positioned in the container in substantially moisture-free conditions and sealed therein against entry of moisture until use. The ankle brace includes an elongate substrate with a reactive system impregnated into or coated onto the substrate. The system remains stable when maintained in substantially moisture-free conditions and hardens upon exposure to moisture to form a rigid, self supporting structure. An elongate, flexible protective pad is positioned on one side of the substrate along its length to provide a cushioning barrier between the substrate and the skin of a patient when the ankle brace is in use. An outer wrapping encloses the substrate and the protective pad. Alternatively, the outer wrapping covers the substrate and the pad provides protection on the other side of the brace next to the skin. The substrate, protective pad and outer wrapping define a first brace segment for being molded while flexible to the lateral aspect of the foot, ankle and lower leg, a second brace segment for being molded to the medial aspect of the foot, ankle and lower leg, and a heel support of reduced width in comparison with the first and second brace segments for supporting the heel and the molded first and second segments.
Patent DE-69632578-D1 (DE)
Inventor: DEBRY F
IPC: G06T15/04
Filed: 1996-02-15
Granted: 2004-07-01
Abstract: Supplemental data, as textured data, for use with geometric data to produce a display image is expanded by relating between display space and model space. A texture map storing supplemental data is enhanced by first applying new texture data as color, to an image in two dimensional display space. The locations for the data in the dimensional model space are determined and transformed into texture map space to receive the applied new texture data. Texture data is placed in the texture map by scan conversion of texels and blending.
Patent DE-69637115-D1 (DE)
Inventor: ALCIME RYSLER
IPC: A61F2/06
Filed: 1996-10-29
Granted: 2007-07-12
Abstract: An expandable supportive endoluminal graft (31) comprising a tubular support component (32) having a lumen, a compliant graft component forming a cover (33) positioned over said tubular support component and/or a linear (34) positioned along the lumen of the tubular support component, and one or more windows (37) formed through said cover (33) and/or linear (34) and/or tubular support (32) in order to feed outside branch arteries or other vessels. <IMAGE>
Patent DE-69711863-D1 (DE)
Inventor: BOWLES GORDON
IPC: B21D22/04
Filed: 1997-04-30
Granted: 2002-05-16
Abstract: A tubing connector non-releasably connected to a tube of tubing string for use downhole in oil and gas well operations, the connector comprising connector body (1) with an end portion fitted concentrically within or over a corresponding end of the tube (2), the end portion having a plurality of depressions (12) coinciding with corresponding depressions (10) on the corresponding end of the tube (2) whereby the connector body (1) and tube (2) are connected together, the depressions (10) and the tube (2) having been formed by localized plastic deformation of the walls of the tube (2).
Patent DE-69712881-D1 (DE)
Inventor: AUDEBERT YVES
IPC: G06F21/35
Filed: 1997-03-21
Granted: 2002-07-04
Abstract: A system including a first unit (2) consisting of a card capable of interacting with a second unit (3) that enables access to a function (1) only under certain conditions. Both units are designed to run software for generating passwords by encrypting a plurality of dynamic variables such as a time-dependent variable and/or a variable dependent on the number of authentication requests received. Encryption is performed using a dynamic encryption key. To synchronise the values of the variables simultaneously but separately generated in the two units, only a few lowest-weight digits of each variable are transferred from the first unit (2) to the second unit (3) by adding them to the transferred password. The synchronisation data is combined with corresponding variables in the second unit in order to calculate a value therein that normally leads to a match between the passwords calculated in the respective units. The match may then enable access to the function.
Patent DE-69714219-D1 (DE)
Inventor: SCHMIDT L
IPC: B29C45/16
Filed: 1997-03-06
Granted: 2002-08-29
Abstract: A multilayer plastic container having enhanced strength for high temperature and pressure applications such as the pasteurization of carbonated juice drinks. The container is commercially cost-effective in comparison to prior art pasteurizable glass containers, and provides all of the advantages of plastic over glass, i.e., lightweight, shatter-resistant, etc. In a particular embodiment, the multilayer container includes inner and outer layers of a relatively high IV virgin PET, e.g., 0.85-0.90 dl/g, and a core layer of post-consumer PET having a substantially lower IV. The container has a relatively tall and slender profile, with high orientation levels in the panel and shoulder, and an oriented thick-walled base with feet. The base preferably has a high profile and angled foot pads which are allowed to move outwardly under creep. According to a method of making a multilayer preform for such container, an enhanced injection rate and mold pressure are utilized to enhance interlayer bonding and prevent separation of the layers in spite of their substantial differences in IV.
Patent DE-69715487-D1 (DE)
Inventor: MORIKAWA MICHIO
IPC: A21C5/08
Filed: 1997-02-07
Granted: 2002-10-24
Abstract: Apparatus for continuously cutting and discharging constant amounts of bread dough, from a mass of bread dough (2) in a hopper (1). The apparatus is characterized by forward projections (5;6) on pairs of opposing rotary cutting blades (4,4') disposed in a bottom opening of the hopper, to draw the bread dough down as the blades rotate. <IMAGE>
Patent DE-69719336-D1 (DE)
Inventor: ISAKSSON MIKAEL
IPC: H04L27/34
Filed: 1997-09-01
Granted: 2003-04-03
Abstract: A multi-carrier transmission system, for example a DMT system. Channel information is transmitted between two transceivers using a plurality of subcarriers. Each subcarrier, or symbol, has a parameter associated with it. The transceivers are adapted to transmit the channel information as a sequence of n groups in which each of the n groups contains information concerning the number of adjacent subcarriers which have the same value as the parameter, together with the actual value of the parameter. The parameter which may have a plurality of discrete values, may be a bit-loading value, or a QAM constellation identifier.
Patent DE-69724098-D1 (DE)
Inventor: OKU TERUO
IPC: A61K31/4439
Filed: 1997-01-31
Granted: 2003-09-18
Abstract: PCT No. PCT/JP97/00233 Sec. 371 Date Aug. 3, 1998 Sec. 102(e) Date Aug. 3, 1998 PCT Filed Jan. 31, 1997 PCT Pub. No. WO97/28153 PCT Pub. Date Aug. 7, 1997This invention relates to a compound of formula (1) wherein R1 is halogen, etc., R2 is halogen, etc., R3 is amino substituted with substituent(s) selected from the group consisting of lower alkyl and acyl, etc., R4 is heterocyclic (lower)alkyl, R5 is lower alkyl, and A1 is lower alkylene, and pharmaceutically acceptable salts thereof, to processes for preparation thereof, to a pharmaceutical composition comprising the same, and to methods of using the same therapeutically in the prevention and/or the treatment of hypertension or the like.
Patent DE-69724229-D1 (DE)
Inventor: MASCHWITZ A
IPC: C23C14/56
Filed: 1997-01-16
Granted: 2003-09-25
Abstract: The present invention provides an improved method for making a solar control sheet having one or more metal layers. In the prior art solar control sheets, each metal layer would normally be non-porous so that water vapor would not be readily transmitted therethrough. However, in this invention the metal layer is rendered porous because it is deposited on a porosity inducing surface. The porosity inducing surface may be the surface of a porous primer layer or a surface which has been roughened. Consequently when the solar control film of this invention is mounted on a window with a water based mounting media, the water can quickly evaporate through the film without causing undesirable cloudiness which is normally associated with water which becomes trapped between the film and the window.
Patent DE-69724784-D1 (DE)
Inventor: HANSEN NIELS-AAGE
IPC: A61M5/20
Filed: 1997-06-12
Granted: 2003-10-16
Abstract: An automatic needle insertion device for a pen shaped syringe comprising a cartridge holder (2) wherein a cartridge with a drug can be accommodated, and a dose setting and injection part (1) by which a wanted dose may be set an subsequently pressed out from the cartridge by pressing a button (12) projecting from the dose setting and injection part (1). The device comprises a mainly tubular housing (31) in which a tubular pen holder (22) in which a pen can be mounted can be axially displaced in a proximal direction to cock a spring (30) which can thereafter be released to drive the pen holder (22) with the pen a set distance in a distal direction.
Patent DE-69728768-D1 (DE)
Inventor: BOSMANS RENE
IPC: C07D401/14
Filed: 1997-05-02
Granted: 2004-05-27
Abstract: The present invention concerns the compounds of formulathe N-oxide forms, the pharmaceutically acceptable acid addition salts and stereochemically isomeric forms thereof, wherein Alk is C1-6alkanediyl or C3-6alkenediyl; R1 is hydrogen or C1-4alkyl; R2 and R3 each independently are hydrogen, C1-6alkyl or C3-7cycloalkyl; or R2 and R3 may also be taken together with the nitrogen atom to which they are attached, thus forming a pyrrolidine, a piperidine or a perhydro azepine ring; R4 is hydrogen or halo; Q is aryl, aryloxy, di(aryl)methyl or heteroaryl; aryl is naphthyl or phenyl, said naphthyl and phenyl may optionally be substituted; and heteroaryl is quinolinyl, isoquinolinyl, pyridinyl, thienyl, indolyl, 2,3-dihydro-1,4-benzodioxinyl, 2,3-dihydro-benzofuranyl or benzodioxolanyl; said heteroaryls may optionally be substituted; it further relates to processes for their preparation, compositions comprising them as well as their use as a medicine; compounds of formula (I) containing a radioactive isotope; a process of marking dopamine D4 receptor sites; and a process for imaging an organ are disclosed.
Patent DE-69730139-D1 (DE)
Inventor: BLATNY JANET MARTHA
IPC: C12N15/67
Filed: 1997-08-28
Granted: 2004-09-09
Abstract: The present invention provides an expression vector comprising an RK2 minimum replicon together with an expression cassette comprising the regulatory functions of a TOL plasmid, and, in particular, an expression vector comprising a RK2 minimum replicon together with a promoter Pm and/or Pu and a corresponding regulatory gene xylS and/or xylR as derived from a TOL plasmid. Such expression vectors may be used to express desired genes in a wide range of gram negative and gram positive bacterial hosts.