baber/WOPTO huggingface dataset:
Patent CA-3095866-A1 (CA)
Inventor: KANAI NAOHIKO
IPC: C07D263/32
Filed: 2019-04-03
Abstract: L'invention concerne un cristal d'un composé d'oxazole spécifique ayant une activité inhibitrice spécifique dirigée contre PDE4, et présentant une excellente stabilité. Plus particulièrement, l'invention concerne un cristal d'un composé d'oxazole représenté par la formule (5), le cristal ayant des pics à des angles de diffraction 2? (°) de 9,6 ± 0,2, 19,1 ± 0,2, et 21,2 ± 0,2 dans un motif de diffraction de rayon X sur poudre mesuré à l'aide de rayons X caractéristiques CuKa.
Patent CA-3096397-A1 (CA)
Title: Protection deployable pour dispositifs d'imagerie par resonance magnetique portables
Inventor: MCNULTY CHRISTOPHER THOMAS
IPC: G01R33/44
Filed: 2019-04-19
Abstract: Selon certains aspects, l'invention concerne un appareil comprenant un dispositif de protection déployable, configuré pour être couplé à un dispositif d'imagerie médicale portable, le dispositif de protection déployable étant en outre configuré pour, lorsqu'il est déployé, éviter l'empiètement à l'intérieur d'une frontière physique par rapport au dispositif d'imagerie médicale portable. Selon certains aspects, l'invention concerne un appareil comprenant un dispositif de protection déployable, configuré pour être couplé à un système d'imagerie par résonance magnétique portable, le dispositif de protection déployable étant en outre configuré pour, lorsqu'il est déployé, délimiter une frontière à l'intérieur de laquelle une intensité de champ magnétique d'un champ magnétique généré par le système d'imagerie par résonance magnétique portable est supérieure ou égale à un seuil donné.
Patent CA-3096511-A1 (CA)
Inventor: SARAGNESE DANIEL
IPC: C08F6/14
Filed: 2019-04-23
Abstract: The present invention is in the field of manufacturing drug-loaded microparticles, and specifically provides processes for producing approximately homogenously sized drug loaded microparticles with high drug loading and reproducible drug release profiles, and which may be provided in a significantly reduced time period.
Patent CA-3096514-A1 (CA)
Title: Coating comprising mcral-x coating layer
Inventor: RAMM JUERGEN
IPC: C23C14/32
Filed: 2019-04-24
Abstract: Coated substrate comprising a substrate (1) comprising a metal substrate surface (11) coated with a coating system (7) consisting of or comprising a functional coating film (5), said functional coating film (5) consisting of or comprising at least one MCr Al-X coating layer, whereas ° the at least one MCr Al-X coating layer is deposited directly on the metal substrate (11), or ° the at least one MCr Al-X coating layer is deposited on an intermediate coating layer (3) that is formed of at least one substrate matching layer (31), wherein the at least one substrate matching layer (31) is deposited directly on the metal substrate surface (11), wherein the layer deposited directly on the metal substrate surface (11), it means respectively the MCr Al-X coating layer if it is deposited directly on the metal substrate surface (11) or the substrate matching layer (31) if it is deposited on the metal substrate surface (11) exhibits: ° epitaxial growth in part or totally, or ° heteroepitaxial growth in part or totally.
Patent CA-3097021-A1 (CA)
Inventor: PATHAPATI TRINATH
IPC: G01N30/46
Filed: 2018-12-31
Abstract: The present invention relates to a method for separating one or more components from a liquid feed mixture in an EBA-SMB operating mode without the need of pumps at the outlets of the EBA columns. The present invention also relates to a simulated moving bed separation device with expanded bed adsorption columns which can be used in the method according to the invention.
Patent CA-3097062-A1 (CA)
Title: Anticorps de liaison a pd-1 et leurs utilisations
Inventor: LI JOHN
IPC: A61P35/00
Filed: 2019-04-12
Abstract: L'invention concerne un anticorps monoclonal isolé ou un fragment de liaison à l'antigène qui se lie de manière spécifique à PD-1 humain. L'invention concerne également une molécule d'acide nucléique codant pour l'anticorps ou le fragment de liaison à l'antigène, un vecteur d'expression, une cellule hôte et un procédé d'expression de l'anticorps ou du fragment de liaison à l'antigène. La présente invention concerne en outre un immunoconjugué, une molécule bispécifique, un récepteur antigénique chimérique, un virus oncolytique et une composition pharmaceutique comprenant l'anticorps ou le fragment de liaison à l'antigène, ainsi qu'une méthode de traitement utilisant un anticorps anti-PD-1 selon l'invention.
Patent CA-3097223-A1 (CA)
Title: Procede, equipement terminal et equipement de reseau permettant de transmettre des informations de facon repetee
Inventor: LIN YANAN
IPC: H04W72/04
Filed: 2018-10-12
Abstract: La présente invention concerne un procédé, un dispositif terminal et un dispositif de réseau permettant de transmettre des informations de manière répétée, le procédé comprenant l'opération suivante : sur des ressources de domaine temporel continues d'au moins un créneau temporel continu, transmettre K canaux de transmission de liaison montante, les K canaux de transmission de liaison montante étant utilisés pour une transmission indépendante de données cibles, K étant un nombre entier supérieur ou égal à 2, et la transmission des K canaux de transmission de liaison montante sur des ressources de domaine temporel continues d'au moins un créneau temporel continu comprend l'opération suivante : lorsque des ressources de domaine temporel restantes dans un m-ième créneau ne peuvent pas transporter un n-ième canal de transmission de liaison montante complet, transmettre le n-ième canal de transmission de liaison montante dans le (m + 1)-ième créneau ; ou, lorsque les ressources de domaine temporel restantes dans le m-ième créneau ne peuvent pas transporter le n-ième canal de transmission de liaison montante complet, transmettre le n-ième canal de transmission de liaison montante incomplet dans les ressources de domaine temporel restantes dans le m-ième créneau, n étant un nombre entier supérieur ou égal à 1 et inférieur ou égal à k, et m étant un nombre entier supérieur ou égal à 1.
Patent CA-3099182-A1 (CA)
Inventor: DEUBER LOUIS
IPC: A47J42/50
Filed: 2019-02-11
Abstract: The present invention relates to a unit which has a container module (M), the container module (M) comprising at least a coffee bean container (10) and a portioning means (2) for metering coffee beans. The container module (M) is designed as a whole to be connected to a coffee device, this connection enabling metered dispensing of coffee beans from the container module (M) into a grinder (4) of the coffee device, and the coffee bean container (10) being closed before the first use and, after being opened, having an opening through which coffee beans enter the portioning means (2). The coffee bean container (10) is coupled to the portioning means (2) so as to be detachable and reconnectable, a coupling element (11) being arranged around the opening, which coupling element is used for connection to the portioning means (2), and the opening being reclosable when the coffee bean container (10) is separated from the portioning means (2). The unit according to the invention allows economical and environmentally conscious handling and consumption of coffee.
Patent CA-3099635-A1 (CA)
Title: Processus et installation pour la production de methanol
Inventor: ESKESEN SOREN GRONBORG
IPC: C07C31/04
Filed: 2019-06-11
Abstract: Un processus de production de méthanol à partir d'un gaz de synthèse par l'intermédiaire d'une réaction d'équilibre est conduit dans un pré-convertisseur de méthanol à l'intérieur d'une certaine fenêtre opérationnelle, ladite fenêtre opérationnelle étant définie par la zone en dessous d'une courbe approximativement linéaire de la pression partielle de monoxyde de carbone par rapport à la température d'eau bouillante pour des températures d'eau entre 210 et 270 °C. Le méthanol de différentes qualités de produit peut être obtenu en fonctionnant dans des zones spécifiques de la fenêtre opérationnelle.
Patent CA-3099999-A1 (CA)
Inventor: BREWER JR HOLLIS BRYAN
IPC: A61K38/17
Filed: 2019-05-10
Abstract: The present specification is directed to systems, apparatus and methods for prophylactically preventing, or for treating the onset and/or progression of Cerebral Amyloid Angiopathy (CAA), acute stroke conditions, or Alzheimer's disease. The progression of, stabilizing, or improving symptoms related to these conditions are treated by monitoring a pathophysiological change indicative of the conditions in a patient, based on the monitoring, determining if amyloid plaque is present in a perivascular space of the patient, optionally determining an extent of amyloid plaque in the perivascular space, and based on the presence of amyloid plaque in the perivascular space of the patient, determining a treatment protocol for the patient. The treatment protocol includes administering to the patient a high density lipoprotein composition derived from mixing a blood fraction with a lipid removing agent.
Patent CA-3100252-A1 (CA)
Title: Information reporting method, data transmission method, user equipment and network side device
Inventor: CHEN JINGJING
IPC: H04L1/18
Filed: 2019-04-09
Abstract: Provided are an information reporting method, a data transmission method, a user equipment and a network side device. The information reporting method is applied to a user equipment, and comprises: reporting information of the number of retransmission times to a network side device.
Patent CA-3100405-A1 (CA)
Title: Adeno-associated viral vector-mediated gene therapy for treating fragile x-associated disorders
Inventor: HAMPSON DAVID R
IPC: C12N15/85
Filed: 2019-05-30
Abstract: The present application provides adeno-associated viral vector-mediated gene therapy for treating Fragile X-associated disorders, including Fragile X Syndrome (FXS). In particular, there is provided a vector comprising an adeno-associated virus (AAV) genome or a derivative thereof and a nucleic acid sequence encoding a Fragile X Mental Retardation Protein (FMRP) isoform that lacks exon 12 and includes exon 14 of the full length FMRP gene, such as a human or a murine Group C FMRP isoform. Also provided are related pharmaceutical compositions comprising this vector, and methods and uses thereof for the treatment of Fragile X-associated disorders, including FXS.
Patent CA-3104186-A1 (CA)
Title: Procede et systeme de formation d'emballages
Inventor: WALSH JOSEPH
IPC: B31B50/10
Filed: 2019-07-08
Abstract: L'invention concerne un procédé de formation d'emballages renforcés. Le procédé peut consister à déplacer une ébauche dans le sens machine sur un transporteur d'ébauche, et à former une bande tubulaire pendant le déplacement d'une première bande de matériau et d'une seconde bande de matériau dans le sens machine. La formation de la bande tubulaire peut consister au moins partiellement à étanchéifier ensemble au moins une partie de la première bande et de la seconde bande pour former une marge étanchéifiée de la bande tubulaire. Le procédé peut en outre consister à former une doublure par découpe de la bande tubulaire, à former une ébauche liée par fixation de la doublure à l'ébauche, et à déplacer l'ébauche liée dans le sens machine sur le transporteur d'ébauche.
Patent CA-3106813-A1 (CA)
Inventor: SJOSTROM ANDERS
IPC: G07F19/00
Filed: 2019-07-18
Abstract: The disclosure relates to a cash depositing and dispensing machine (100) comprising:a machine body (105) having outer circumferential walls (106), and an arrangement (110) comprising:a cash input/output unit (120) having an interface (122) for allowing depositing and dispensing of cash, a cash handling unit (130), and a cash storage unit (140), wherein said cash input/output unit (120), said cash handling unit (130), and said cash storage unit (140) being arranged in relation to each other in relation to said machine body (105) between: a closed position (P1) for which the outer circumferential walls (106) of the machine body (105) enclose the cash handling unit (130) and the cash storage unit (140) so as to prevent access thereto, and a service position (P2) and a cash access position (P3) for which at least the cash handling unit (130) protrudes from the machine body (105) so as to allow access thereto.
Patent CA-3109119-A1 (CA)
Inventor: SPINDLER EILEEN
IPC: C12M1/36
Filed: 2019-08-14
Abstract: The present disclosure provides methods, automated modules, and instruments for enrichment of live cells that have been edited by nucleic acid-guided nuclease genome editing. The disclosure provides improved methods and modulesincluding high throughput methods and modulesfor enriching for cells that have been subjected to editing.
Patent CA-3110424-A1 (CA)
Inventor: COOK CHRISTOPHER MICHAEL
IPC: B67D1/12
Filed: 2019-06-14
Abstract: A beverage dispenser 10 includes a gas infusion device 22 configured to infuse a gas into a base liquid to form a gas-infused liquid, a mixing chamber 205 configured to mix the gas-infused liquid and a concentrate to thereby form a reconstituted beverage, a first flow control 210 configured to decrease pressure of the gas-infused liquid prior to mixing with the concentrate, and a second flow control 220 configured to decrease pressure of the concentrate prior to mixing with the gas-infused liquid. A restrictor device 74, 76 downstream from the mixing chamber 205 and configured to apply backpressure on the concentrate and the gas-infused liquid, and a dispensing valve 70 is configured to dispense the reconstituted beverage.
Patent CA-3111757-A1 (CA)
Inventor: KABERG JOHARD LEONARD
IPC: G06V40/70
Filed: 2019-08-22
Abstract: There is provided a method and corresponding system for handling and/or generating anonymous biometric and/or behavioural data. The method comprises the steps of mapping (S1) biometric data originating from a subject into a biometric key using a one-way locality-sensitive hash function or receiving the biometric key. The method also comprises storing (S2) additional anonymous behavioural data bound to this key into an existing biometric trajectory in a database, wherein the behavioural data describes the user behavior of the subject. The method is performed to anonymize biometric data from a multitude of individuals, or subjects, per key, where each biometric key maps to biometric data of several subjects, and such a set of subjects resulting in the same biometric key is called a hash group, and a biometric trajectory is developed for each hash group.
Patent CA-3116802-A1 (CA)
Inventor: LEBLANC DEREK
IPC: A61N5/06
Filed: 2019-10-21
Abstract: The invention provides a system and related equipment for the precise measurement of the output characteristic of a light source, e.g., a dental light curing unit (LCU) or light for photodynamic therapy, using a light collector, a light detector, and a computer programmed to deliver the value of the output characteristic of the light source to the user. The systems allow for the determination of a proper 5 exposure time or the selection of a light source as needed for a specific application. The invention also provides a light device.
Patent CA-3118052-A1 (CA)
Inventor: NAYDENOV VALERI
IPC: B01D1/26
Filed: 2019-10-21
Abstract: The present invention describes a process for continuous fractionation of CTO (crude tall oil) to RTD (refined tall diesel), said process comprising: - when removing a stream of TOP (tall oil pitch) the CTO is fed through at least two evaporation zones arranged in series so that one stream of CTO is fed from a first evaporation zone to a second evaporation zone, wherein a TOP stream is produced and fed from the second evaporation zone, wherein a first vapor stream is produced within the first evaporation zone and a second vapor stream is produced within the second evaporation zone and wherein there is a temperature difference of at least 10°C between the first vapor stream and the second vapor stream; and - feeding the first vapor stream and the second vapor stream into a subsequent fractionation column to produce a stream of RTD from the fractionation column, wherein the first vapor stream and the second vapor stream are being fed to different positions, relative to the column height, in the fractionation column, where different conditions are applied to ensure suitable fractionations of a more fatty acid rich material and a more rosin rich material, respectively, and which different positions in the fractionation column are separated by packing means.
Patent CA-3118332-A1 (CA)
Title: Method for controlling a wind power installation
Inventor: BROMBACH JOHANNES
IPC: F03D7/04
Filed: 2021-05-12
Abstract: The invention relates to a method for controlling a wind power installation (100), wherein the wind power installation (100) has a rotor (106) with rotor blades (108) with an adjustable blade angle (8), and the rotor (106) can be operated with a variable rotational speed (n), and wherein the wind power installation (100) is operated in a partial load range in which sufficient wind is not present to operate the wind power installation (100) with rated power (PN), the wind power installation (100) can be operated as an operating point (302, 308, 310) which can be specified in a changing fashion, and the operating point (302, 308, 310) is characterized by the blade angle (8) and a tip speed ratio (A), and wherein the operating point (302, 308, 310) can be represented in a A8 diagram, wherein in the A8 diagram the tip speed ratio (A) is plotted against the blade angle (8), and the operating point (302, 308, 310) can be represented in the A8 diagram as a value pair composed of a blade angle (8) and tip speed ratio (A), wherein each operating point (302, 308, 310) is assigned a power coefficient (Cp value), and a plurality of operating points (302, 308, 310) with the same Cp value can be represented as an iso-characteristic curve in the A8 diagram, comprising the steps: operating the wind power installation at a normal operating point (302) at which the wind power installation (100) is not operated in a throttled fashion if there is no request for throttling, operating the wind power installation (100) at a throttled operating point (308) at which, in response to a throttle request, the wind power installation (100) is operated with output power (PA) which is throttled in comparison with the normal operating point (302), and changing over the operation of the wind power installation from the throttled operating point (308) to a reserve operating point (310) at which the wind power installation (100) is operated with higher output power in comparison with the throttled operating point (308), in reaction to a power increase request wherein the throttled operating point (308) has an increased tip speed ratio in comparison with the reserve operating point (310), and the throttled operating point (308) lies on an associated iso-characteristic curve in the A8 diagram, and the associated iso-characteristic curve has, at the throttled operating point (308), a negative characteristic curve gradient at which the tip speed ratio decreases as the blade angle increases.
Patent CA-3119629-A1 (CA)
Inventor: LEE JANICE HSIU MEI
IPC: C12N7/06
Filed: 2019-11-14
Abstract: This disclosure relates to methods for use in inactivating viruses. The virus inactivation methods are for use in continuous process manufacturing of a biologic such as an antibody, and include separating an eluate using a column, subjecting said eluate to an orthogonal treatment of low pH and detergent simultaneously wherein, the time for viral inactivation is reduced. In addition, the detergent can be added to buffer system in purification process to achieve the same effect. The biologic in each treatment case is retained.
Patent CA-3119938-A1 (CA)
Title: Method and apparatus for reducing the risk of neonatal neurological injury
Inventor: EVANS MARK
IPC: A61B5/02
Filed: 2019-11-14
Abstract: A method for reducing the risk of neurological injury to a neonatal human child includes the steps of: (I) monitoring in a pregnant patient during labor at least a first set of parameters indicative of a present level of risk for neurological injury to the child as a fetus; (II) during the period between a cervical dilatation of 10cm in the patient and delivery of the child and/or during at least the first 5 minutes following delivery of the child, determining a present level of risk for neurological injury to the child based on the at least first set of parameters at a given point in time during labor that is between a cervical dilatation of 10cm in the patient and delivery of the child, and wherein the determined present level of risk corresponds to one of a plurality of predetermined levels of predicted risk for neurological injury to the child as a neonate; and (III) commencing monitoring the child for one or more postnatal parameters indicative of neurological injury or its onset within the first 5 minutes following delivery of the child, and/or performing one or more measures for treating the child for neurological injury or its onset within the first 60 minutes following delivery of the child.
Patent CA-3124351-A1 (CA)
Inventor: WILLIAMS FREDERICK J
IPC: G01J5/00
Filed: 2019-06-26
Abstract: A method and system are provided relating to washroom traffic. A method comprises communicating, from a hygiene dispenser in a washroom to a washroom controller, use data describing dispense events from the hygiene dispenser, wherein a dispense event defines an actuation of the dispenser to dispense consumable product. A thermal sensor detects thermal events proximate an entrance of the washroom. The thermal sensor communicates to the washroom controller thermal data describing the thermal events. The use data and thermal event data are analyzed to determine a number of dispense events and a number of occupants that entered in the washroom. The number of dispense events is compared to the number of occupants. In response to determining that the number of occupants differs from the number of dispense events by a predetermined measure, a communication is provided specifying that the hygiene dispenser may be malfunctioning.
Patent CA-3130701-A1 (CA)
Inventor: NI YAJIN
IPC: A61K35/17
Filed: 2020-03-20
Abstract: Provided herein are improved methods for robust TCR+ cell depletion and production of populations of TCR- cells, which can be beneficial to minimize the GvHD risk in patients receiving allogeneic CAR T cell therapy. Provided herein are methods that increase the efficiency of depleting TCR+ cells from a population of cells in order to significantly reduce any residual levels of TCR+ cells present in cell populations in which expression of endogenous TCR has been reduced or eliminated. Associated kits and cell populations are also provided.
Patent CA-3131055-A1 (CA)
Title: Curtain wall
Inventor: CLAEYS STEPHANIE CATHARINA R
IPC: E04B2/96
Filed: 2020-03-13
Abstract: A curtain wall that comprises one or more mullions (2) and one or more transoms (3) and panels (4-4A) that are fitted with their edges (5) at least in the mullions (2) and optionally in the transoms (3), characterized in that the aforementioned mullion is assembled from at least an inner profile (2C) and an outer profile (2A) joined together by means of one or more plastic profiles (2B), wherein at least the inner profile (2C) consists substantially of steel.
Patent CA-3131704-A1 (CA)
Inventor: BUTLER ROBERT P
IPC: E04H12/24
Filed: 2016-06-09
Abstract: A prosthetic apparatus for reinforcing a top of a rotted/deteriorating upstanding pole. A prosthetic embodiment ensleeves the pole at its uppermost end to provide an elongate support on which insulators and other various equipment can be mounted in a secure fashion. A second embodiment reinforces a cross arm of a pole. The present invention provides a simplistic and inexpensive fix to preexisting rotting utility poles while also enabling a safe and efficient installation.