baber/WOPTO huggingface dataset:
Patent PT-1499274-E (PT)
Title: Multiple-chamber medical container and bag for enclosing same
Inventor: NAGAO KATSUYOSHI
IPC: B65D81/32
Filed: 2003-04-25
Abstract: A multiple-chamber medical container 1 comprises a container body 5 having two chambers 9, 11 for containing medicaments therein and a partitioning weak seal portion 13 for separating the chambers 9, 11 from each other, a medicinal outlet portion 7 attached to the container body 5 for discharging the medicaments from the chambers therethrough, and an openable small container 15 disposed in the first chamber 9 and having a medicament enclosed therein, the partitioning seal portion 15 being openable so as to cause the chambers 9, 11 to communicate with each other for use. The small container 15 can be opened by opening the partitioning weak seal portion 13.
Patent PT-1532124-E (PT)
Title: Use of nitrile derivatives as medicament.
Inventor: BAILEY ANDREW
IPC: C07D295/18
Filed: 2003-06-23
Abstract: The present invention relates to compounds and compositions for treating diseases associated with cysteine protease activity. The compounds are reversible inhibitors of cysteine proteases S, K, F, L and B. Of particular interest are diseases associated with Cathepsin S. In addition this invention also discloses processes for the preparation of such inhibitors.
Patent PT-1594833-E (PT)
Title: 1-phenylalkanecarboxylic acid derivatives for the treatment of neurodegenerative diseases
Inventor: VILLETTI GINO
IPC: C07C233/11
Filed: 2004-02-19
Abstract: 1-Phenylalkanecarboxylic acid derivatives, the processes for the preparation thereof and the use thereof in the treatment and/or prevention of neurodegenerative diseases such as Alzheimer's disease.
Patent PT-1580093-E (PT)
Title: Vehicle, especially rail guided vehicle, comprising articulated interconnected bodies
Inventor: KUECHLER THOMAS
IPC: B61G5/00
Filed: 2005-03-11
Abstract: u Track-guided vehicle comprises hinges (SNWG *>, SWG *>) supporting a freight car (MWK) and permitting oscillations about a longitudinal axis of the car. The oscillations of the car are coupled in the hinges so that the oscillation angle of the freight car in one hinge (SWG *>) and the oscillation angle of the freight car in the other hinge (SNWG *>) stay together. The freight car is supported over both hinges. Preferred Features: The oscillation movements of the freight car is dampened in the hinges.
Patent PT-1757150-E (PT)
Title: Inter-mode/inter-rat handover
Inventor: REXHEPI VLORA
IPC: H04L12/56
Filed: 2005-06-14
Abstract: There is disclosed a method of packet switched handover in a communications system having at least two modes of operation, the method comprising, at a terminal of the system, associating identifiers of each mode of operation, and responsive to a packet switched connection handover to a new mode, allocating the connection from an identifier of the existing mode to the associated identifier of the new mode.
Patent PT-1856073-E (PT)
Title: A process for the preparation of an 11-(4-substituted-i-piperazinyl)dibenzo[b,f][1,4]thiazepine derivative
Inventor: COMELY ALEXANDER CHRISTIAN
IPC: C07D295/18
Filed: 2005-12-21
Abstract: Method for preparing an 11-piperazinyl-dibenzo[b,f][1,4]thiazepine derivative (I), or salt, by reacting the 11-oxo compound (II) and a piperazine (III) in presence of a titanium tetra(alkoxide) (A). Method for preparing an 11-piperazinyl-dibenzo[b,f][1,4]thiazepine derivative of formula (I), or salt, by reacting the 11-oxo compound (II) and a 4-A-piperazine (III) in presence of a titanium tetra (alkoxide) Ti(OR)4 (IV). [Image] A : hydrogen, 2-hydroxyethyl or 2-(2-hydroxyethoxy)ethyl; R : 1-8C linear or branched alkyl. ACTIVITY : Tranquilizer; Neuroleptic. No test details given. MECHANISM OF ACTION : Antidopaminergic.
Patent PT-1874748-E (PT)
Title: 2 -aminocarbonyl substituted piperazine or diaza-cyclic compounds as apoptosis protein inhibitor (iap) modulators
Inventor: ECKL ROBERT
IPC: A61P35/00
Filed: 2006-04-13
Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, solvates, hydrates or pharmaceutically acceptable formulations thereof. These compounds may be used to modulate cellular proliferation and to prevent and/or treat proliferative diseases.
Patent PT-2236600-E (PT)
Title: Phytases
Inventor: KENSCH OLIVER
IPC: A23K1/165
Filed: 2005-10-17
Abstract: The present invention relates to enzymes and processes. In particular, there is described a host cell transformed or transfected with a nucleic acid encoding a bacterial phytase enzyme and variants thereof.
Patent PT-2440467-E (PT)
Title: Vessel and method for making the same
Inventor: HERMAN PETER
IPC: B65D1/26
Filed: 2010-06-11
Abstract: A spouted cup composed of a sheet of flexible material, cut, rolled, and affixed to form a frusto-conically shaped base region (101). The sheet when rolled including an upper region having two opposing flaps (103, 113), each flap delineated from a remaining portion of the sheet by a path (118) along which the sheet is scored, so that the flaps, when folded along their respective paths, define a single elevated drinking portion having a spout (104) formed between an extension of the base region and at least one of the two flaps.
Patent PT-720508-E (PT)
Inventor: CLARK CARL
IPC: B01D61/28
Filed: 1994-09-21
Abstract: A device for the dialysis of a sample. The device embodies a hermetically sealed sample chamber formed by a gasket with dialysis membranes affixed to each side in substantially parallel relationship. The gasket is impermeable to the sample being dialyzed, but is penetrable and reusable such that a needle or the like can be inserted through the gasket into the chamber and then withdrawn without sample being permitted to leak. The gasket is of sufficient thickness to accommodate insertion of a needle. In a further embodiment, the device is fitted into a rigid housing containing windows exposing the dialysis membranes and further containing a channel parallel to the dialysis membranes for directing a needle into the gasket in a direction substantially perpendicular to the edge of the gasket so that the needle can access the chamber without contacting the surfaces of the membranes.
Patent PT-724587-E (PT)
Inventor: BURNS BARRY
IPC: A61P31/04
Filed: 1994-09-29
Abstract: The present invention relates to compositions comprising analogues of purine nucleotides containing a ring-expanded ("fat") heterocyclic ring, in place of purine, and an unmodified or modified sugar residue, pharmaceutically acceptable derivatives of such compositions, as well as methods of use thereof. In particular, these compositions may be utilized in the treatment of certain cancers, bacterial, fungal, parasitic and viral infections, including, but not limited to, Acquired Immunodeficiency Syndrome (AIDS) and hepatitis.
Patent PT-739172-E (PT)
Inventor: HALL JASON HAMILTON
IPC: A42B1/20
Filed: 1995-01-06
Abstract: PCT No. PCT/AU95/00005 Sec. 371 Date May 17, 1996 Sec. 102(e) Date May 17, 1996 PCT Filed Jan. 6, 1995 PCT Pub. No. WO95/18549 PCT Pub. Date Jul. 13, 1995An article of headwear is provided which includes a substantially forwardly projecting peak or visor, an adjustable head engaging band and a length or sheet of material, the head engaging band being attached or attachable to the peak or visor at or near a rear edge thereof, the length or sheet of material being attached or attachable to the peak or visor and extending rearwardly thereof, whereby the peak or visor may be positioned on a wearer's head such that the material covers the wearer's head and hangs therefrom about the shoulders and neck of the wearer, wherein the head engaging band is positioned about a rear of the wearer's head such that the peak or visor is held in position thereon, and the material has a plurality of fasteners to adjust and fasten the material into a plurality of positions to protect a wearer's neck, head, and/or face.
Patent PT-835489-E (PT)
Inventor: GARY SCOTT P
IPC: G11C29/00
Filed: 1996-06-05
Abstract: Errors in data stored in the memory of a computer are detected prior to use of the data. A protected data type is declared in writing a program in which errors in critical data must be detected before the data are used. The invention is preferably implemented on a personal computer system (10) or in a microcontroller for a device. When a protected data item is initialized, both the protected data item and its corresponding bit-inverted form are stored in memory. A constructor function is used to determine the bit-inverted form. Any time that the protected data item is subsequently accessed for use by an application program, either the stored protected data item or its corresponding bit-inverted form are inverted for comparison to the other stored data item. Any difference detected in this comparison indicates that a change has occurred in either or both of the protected data item and its corresponding bit-inverted form within memory. Depending upon the application program in which the invention is used, an appropriate action is taken upon detecting such an error, such as providing an indication of the error and terminating further execution of the program.
Patent PT-837976-E (PT)
Inventor: ANDERSSON HANS
IPC: E06B9/58
Filed: 1996-06-18
Abstract: PCT No. PCT/SE96/00792 Sec. 371 Date Mar. 4, 1998 Sec. 102(e) Date Mar. 4, 1998 PCT Filed Jun. 18, 1996 PCT Pub. No. WO97/01015 PCT Pub. Date Jan. 9, 1997Safety blinds for installation in an opening in a building such as a door or window includes a closure covering the opening, a plurality of projections along the side edges of the opening and a plurality of corresponding apertures along the side edges of the closure, whereby locking the projections into the openings prevents the closure from opening and also prevents the side edges of the closure from being displaced from the side edges of the opening. In another embodiment, the projections from the closure cooperate with a continuous channel along the edge of the opening whereby the projections can move within the channel for opening and closing the closure and can be locked in position for again preventing the closure from being opened.
Patent PT-917430-E (PT)
Inventor: KONIECZNY-JANDA GERHARD
IPC: A23K20/189
Filed: 1997-05-06
Abstract: The invention relates to the preparation of enzyme pregranules with stable activity which can be incorporated into particles of a granular animal feed. The invention further relates to the pregranules with stable activity which are obtained by the preparative processes and can be incorporated into granular animal feeds.
Patent PT-1007232-E (PT)
Inventor: HARTOG HUIBERT WILLEM DEN
IPC: B21B1/26
Filed: 1997-06-09
Abstract: Method for the manufacture of a steel strip, wherein molten steel is cast into a slab, conveyed through a furnace, roughed in a roughing apparatus and finish-rolled in a finishing apparatus. The method comprises an endless or semi-endless process having either step a or step b, wherein a and b respectively comprise (a) manufacturing a ferritically rolled steel strip, wherein the slab is rolled in the roughing apparatus in the austenitic range and then cooled to a ferritic structure, and wherein the strip is rolled in the finishing apparatus at speeds essentially corresponding to the entry speed into the finishing apparatus, and (b) manufacturing an austenitically rolled steel strip, wherein the strip leaving the roughing apparatus is heated to the austenitic range and is rolled in the finishing apparatus and then cooled down to the ferritic range. In both step a and b, there is no material connection between the steel in the continuous casting machine and the steel being rolled in the finishing apparatus, and the strip is fed from the roughing apparatus to the finishing apparatus without intermediate storage. Additional steps include cutting the ferritically or austenitically rolled strip, after reaching the desired finished thickness, to portions of the desired length, and coiling the cut portions.
Patent PT-908176-E (PT)
Inventor: BJORKMAN SVEN
IPC: A61K31/445
Filed: 1998-09-18
Abstract: Stable, aqueous form of (+)-(R)-thalidomide or (-)-(S)-thalidomide contains the enantiomer of thalidomide dissolved in pure form in isotonic glucose solution and has a pH ≤ 5.5. An Independent claim is also included for the production of the aqueous thalidomide solution, comprising: (a) adding (+)-(R) or (-)-S-thalidomide to isotonic glucose at pH 4-5; (b) shaking until dissolution is complete; and (c) treating with ultrasound and filtering under aseptic conditions. Use of pure enantiomers of thalidomide allows water-stable solutions that do not give rise to toxicological effects. The enantiomers have higher solubility in water than the racemate. At pH ≤ 5.5, hydrolysis of thalidomide does not occur. Solutions are suitable for parenteral administration.
Patent PT-1044203-E (PT)
Inventor: HUDKINS ROBERT L
IPC: A61P25/14
Filed: 1998-12-30
Abstract: Compounds defined by the following general structure are disclosed: These compounds display pharmacological activities, including inhibition of tyrosine kinase activity and enhancement of the function and/or survival of trophic factor responsive cells, e.g., cholinergic neurons.
Patent PT-1074473-E (PT)
Inventor: MAZZONI ANDREA
IPC: B65B25/24
Filed: 1999-08-05
Abstract: A method for packaging skeins (3) shaped as a circular ring of a flexible element (33) of elongated shape, in particular a cable or a hose, wherein the turns (2) are held unitarily to each other, comprises the following phases: sustaining the skein (3) in overhang towards a binding station (9) holding it by the clamping of opposite planar faces (4) of the skein (3) effected in correspondence with at least a first portion (5a) of the skein (3); binding the skein (3) in correspondence with at least its second, free, portion (5b) which projects from the first held portion (5a); rotating the skein (3) around its own axis of symmetry (3a) by a predetermined angle ( beta ) with respect to the position of the skein (3) in the previous binding phase; and binding the skein (3) again in correspondence with its own rotated position. The invention further relates to a machine (1) that realises the method.  <IMAGE>
Patent PT-1073907-E (PT)
Inventor: MOOS ERICH
IPC: H02J13/00
Filed: 1999-03-05
Abstract: The method involves dividing communication channels (m) into communication groups (GRI,GRII,GRIII) with the same characteristics or parameter values, with one free communication channel within each communication group selected. A selection center (Z) is held in a waiting position when all the communication channels are occupied, until at least one of the communication channels is free.
Patent PT-1144452-E (PT)
Inventor: HEAVNER GEORGE A
IPC: C07K16/28
Filed: 1999-11-02
Abstract: Modified antibodies with improved pharmacokinetic properties are disclosed. The antibodies bind to one or more human integrin receptors selected from the group consisting of GPIIb/IIIa,  alpha <v> beta 3 and Mac-1, and comprise one to about six organic moieties which are covalently bonded to specific sites on the antibodies. The organic moieties can each independently be a hydrophilic polymeric group, a fatty acid group, a fatty acid ester group, a lipid group or a phospholipid group. Also disclosed is a method of treating a human with a disease or disorder in which cells expressing GPIIb/IIIa, alpha v beta 3 and/or Mac-1 play a pathophysiological role. The method comprises administering an effective amount of one or more antibodies of the invention to a human in need thereof.
Patent PT-1077785-E (PT)
Inventor: BELLONI ANTONIO
IPC: B23K9/127
Filed: 1999-12-21
Abstract: Two pipes are arranged, when forming a deep sea pipeline, end to end thereby defining a circumferentially extending narrow angled (less than 10 degrees) groove. Two arc welding torches are arranged directly adjacent to each other on a single carriage that moves around the pipes, thereby forming a twin arc welding system. The position of the arc of each torch is independently oscillated between the walls of the groove to form a weld therein. The arcs are guided automatically by an electronic guidance system, wherein electrical characteristics (such as arc current voltage and/or impedance) of the welding of each torch with regard to one of the two pipes are compared with the corresponding electrical characteristics relating to the other of the pipes. The position of an arc of a torch may thus be aligned with the center line of the groove.
Patent SG-1893-G (SG)
Title: Biologically active fragments of the human antihemophilic factor and method for their preparation and pharmaceutical preparations
IPC: A61K35/16
Filed: 1993-01-05
Abstract: Novel, biologically active fragments of human anti- hemophilic factor, processes for their preparation, pharmaceutical preparations containing them and the use of such fragments in the treatment of patients suffering from haemophilia.
Patent IE-38883-L (IE)
Title: Diazepine derivatives
IPC: A61P25/08
Filed: 1974-02-06
Abstract: 1456161 Thienotriazolodiazepines F HOFFMANN-LA ROCHE & CO AG 7 Feb 1974 [8 Feb 1973] 05683/74 Heading C2C Compounds of the general formula (R 1 = halogen, NO 2 , NH 2 , alkanoyl; R 2 = pyridyl or thienyl optionally substituted adjacent to linking position, phenyl, o-trifluoromethylphenyl, o - halophenyl, o,o<SP>1</SP> - dihalophenyl, o - nitrophenyl; R 3 = H, OH, alkoxycarbonyl, alkanoyloxy; R 4 = H, alkyl, alkanoyl, hydroxyalkyl, mercaptoalkyl, alkoxycarbonyl, aminocarbonyl, haloalkyl, alkoxyalkyl, alkylthioalkyl, aralkoxyalkyl, cyanoalkyl, alkoxycarbonylalkyl, alkoxycarbonylaminoalkyl, alkylcarbonyloxyalkyl, aminocarbonyloxyalkyl, dialkylaminocarbonyloxyalkyl, CN, alkyl NR 5 R 6 , COO alkyl NR 5 R 6 , CONH alkyl NR 5 R 6 ; R 5,6 = H, alkyl, hydroxyalkyl or NR 5 R 6 = monocyclic saturated 5-6 membered ring optionally containing an oxygen or further nitrogen atom; n = 0,1) and their acid addition salts are prepared by (a) cyclizing a compound of the formula (b) -n = O- cyclising a compound of the formula (c) -R 1 = halogen or NO 2 - halogenating or nitrating the corresponding 2-unsubstituted compound, (d) -R 4 = alkanoyloxidizing the corresponding 9-(α-hydroxyalkyl) compound, (e) -R 4 = alkylcarbonyloxyalkyl or aminocarbonyloxyalkylesterifying the corresponding alcohol, (f) -R 4 = alkoxyalkyl, aralkoxyalkyl, alkylthioalkyl or alkyl NR 5 R 6 - reacting a corresponding 9-A. alkyl compound with BR (one of A,B = OH, SH or NHR 5 and the other = leaving atom or group; R = alkyl or (one of A,B = OH) aralkyl, or (B = NHR 5 )H or hydroxyalkyl, or NRR 5 = monocyclic saturated 5-6 membered ring optionally containing an oxygen or further nitrogen atom), (g) -R 4 = alkylcarbonyloxyalkyl or dialkylaminocarbonyloxyalkyl-reacting the corresponding alcohol with a reactive derivative of the appropriate alkanoic or dialkylcarbamic acid, (h) -R 4 = alkoxycarbonylaminoalkylreacting a corresponding 9-K alkyl compound with L.COO- alkyl (one of K,L = NH 2 and the other = leaving atom or group) or (i) -R 4 = primary hydroxyalkylreducing a corresponding 9-alkoxy carbonyl or alkoxycarbonylalkyl compound, optionally followed by salt formation. The preparation of thienodiagepines of the formulµ and 2-amino, chloroacetamido and aminoacetamido-3-thienyl 2<SP>1</SP>-pyridyl ketone is described. The above compounds are anticonvulsants, sedatives, muscle relaxants, tranquilizerx and anxiolytics and may be administered in the form of pharmacetuical preparations containing them in association with a carrier.
[GB1456161A]
Patent IE-780365-L (IE)
Title: Daunorubicin derivatives
IPC: A61P35/00
Filed: 1978-02-20
Abstract: 9-Desacetyl-9-ethylen oxide daunorubicin hydrochloride is an effective antitumor antibiotic.
[US4251513A]
Patent IE-40836-L (IE)
Title: Benzoxazoline derivatives.
IPC: A01N43/76
Filed: 1975-03-18
Abstract: Compounds represented by the formula <IMAGE> wherein R1 and R2 each are hydrogen or a phenyl; R3 is cyano; R5OCO- in which R5 is a lower alkyl having 1-8 carbons, cycloalkyl having 3-6 carbons, alkenyl having 2-8 carbons, alkynyl having 2-8 carbons or phenyl; R6SO2- in which R6 is a lower alkyl having 1-8 carbons, cycloalkyl having 3 to 6 carbons or phenyl; (R7)(R8)NCO- in which R7 and R8 each are hydrogen or a lower alkyl having 1-4 carbons, cycloalkyl having 3-6 carbons, alkenyl having 2-4 carbons or phenyl, or R7 and R8 together with the nitrogen atom to which they are attached are a 3-7 membered ring which may contain a further hetero atom; or R9CO- in which R9 is a lower alkyl having 1-4 carbons, cycloalkyl having 3 to 6 carbons or phenyl; and R4 is hydrogen or a lower alkyl having 1-4 carbons, AND SALTS THEREOF, HAVING ACTIVITY WHICH INFLUENCES PLANT GROWTH, PROCESSES FOR MAKING SUCH COMPOUNDS, COMPOSITIONS FOR USING THE COMPOUNDS AND METHODS OF USING THE COMPOUNDS TO INFLUENCE PLANT GROWTH ARE DISCLOSED.
[US4028089A]
Patent IE-40874-L (IE)
Title: Extruding tubes
IPC: B29C48/335
Filed: 1975-03-21
Abstract: An improvement in the process of producing a double-walled synthetic plastic tube having a concentric outer tube and an inner tube wherein an outer tube of molten synthetic plastic is extruded from an annular die and passing to a mold cavity formed by a divided mold having two cooperating endless recirculating trains of mold halves which close to complete the mold cavity and an inner tube of molten synthetic plastic is extruded from a die orifice located in the interior of said mold which improvement comprises introducing a first gas into the space between said inner tube and said outer tube before said synthetic plastic has fully hardened, said gas being at a pressure above atmospheric and at a temperature at or above the softening point of said synthetic plastic and permitting said outer inner tubes to cool; an apparatus for carrying out the process comprising an extruder having a first die disposed over a first mandrel to define a first annular space through which molten synthetic plastic can flow en route to a mold cavity of the type described, a second annular die concentric to a first mandrel and a second mandrel concentric to said first die, said second mandrel and said second die disposed to define a second annular space through which additional molten synthetic plastic can flow wherein a first gas channel entering the region between the first annular space and the second annular space is provided to supply fluid gas between the outer wall of the inner tube and the inner wall of the outer tube as the tubes emerge from the respective dies.
[US3996323A]