baber/WOPTO huggingface dataset:
Patent JP-4083384-B2 (JP)
IPC: C08G65/329
Filed: 1998-01-23
Granted: 2008-04-30
Abstract: This invention relates to hydrolytically degradable gels of crosslinked poly(ethylene) glycol (PEG) structures. Addition of water causes these crosslinked structures to swell and become hydrogels. The hydrogels can be prepared by reacting two different PEG derivatives containing functional moieties at the chain ends that react with each other to form new covalent linkages between polymer chains. The PEG derivatives are chosen to provide covalent linkages within the crosslinked structure that are hydrolytically degradable. Hydrolytic degradation can provide for dissolution of the gel components and for controlled release of trapped molecules, including drugs. Reagents other than PEG can be avoided. The hydrolysis rates can be controlled by varying atoms adjacent to the hydrolytically degradable functional groups to provide substantially precise control for drug delivery in vivo.
Patent JP-4248746-B2 (JP)
IPC: B01L99/00
Filed: 1999-02-18
Granted: 2009-04-02
Abstract: Provided is a liquid dispensing device for delivering defined volumes comprising (a) a reagent fill channel, (b) one or more metering capillaries connected to the reagent fill channel and having an exit, and (c) one or more sources of gas connected to the reagent fill channel, wherein after filing the one or more metering capillaries the reagent fill channel can be drained of liquid while liquid is retained in the one or more metering capillaries, and the source of gas can be operated to eject the liquid in the metering capillaries.
Patent JP-4488622-B2 (JP)
IPC: C07K7/00
Filed: 1999-07-06
Granted: 2010-06-23
Abstract: The invention relates to new peptides formed of at least seven subsequent amino acids of the amino acids in position 12-40, counted from the N-terminal end, in the sequence constituting human lactoferrin, and preferably modifications thereof. The invention also relates to medicinal products comprising such peptides, especially intended for treatment and prevention of infections, inflammations and tumours. Furthermore, the invention relates to food stuff, e.g. infant formula food, comprising the above mentioned peptides.
Patent JP-3704055-B2 (JP)
IPC: C07D473/00
Filed: 2001-05-07
Granted: 2005-10-05
Abstract: The present invention relates to highly diastereoselective processes for production of cis-nucleosides and nucleoside analogues and derivatives in high optical purity and intermediates useful in those processes.
Patent JP-3591777-B2 (JP)
IPC: A61P25/00
Filed: 2001-12-20
Granted: 2004-11-24
Abstract: The present invention relates to a method of treating disorders of the Central Nervous System (CNS) and other disorders in a mammal, including a human, by administering to the mammal a CNS-penetrant alpha 7 nicotinic receptor agonist. It also relates to pharmaceutical compositions containing a pharmaceutically acceptable carrier and a CNS-penetrant  alpha 7 nicotinic receptor agonist.
Patent JP-3653494-B2 (JP)
IPC: H04N21/63
Filed: 2000-05-10
Granted: 2005-05-25
Abstract: A system includes a content creator (12), a transmitting source (14), and a receiver platform (16) for communicating enhancement data associated with audio/video content according to a protocol without layering capability. A receiver platform (16) detects for a first announcement and a second announcement (402), the first announcement being associated with non-layered enhancement data, and the second announcement being associated with layered enhancement data having a plurality of layers. Each layer includes one or more sources of trigger files or one or more sources of resource files. Alternatives presented in the second announcement are examined (408), the alternatives containing different collections of the layers of enhancement data. One of the alternatives in the second announcement is selected (410) based on the capacity of the second receiver platform. One or more layers containing respective trigger files and resource files associated with the selected alternative are received (412). The enhancement data may include enhancement data according to an Advanced Television Enhancement Forum Specification.
Patent JP-4763954-B2 (JP)
IPC: C07D241/04
Filed: 2000-11-29
Granted: 2011-08-31
Abstract: The invention refers to a novel process for the preparation of {2-[-(alpha-phenyl-p-chlorobenzyl)piperazin-1-yl]ethoxy}acetic acid, which comprises hydrolyzing an N,N-disubstituted {2-[-(alpha-phenyl-p-chlorobenzyl)piperazin-1-yl]ethoxy}acetamide, wherein said substituents are selected from alkyl groups having 1 to 4 carbon atoms optionally substituted by a phenyl group, alkenyl groups having 2 to 4 carbon atoms or cyclohexyl groups, or the substituents together with the adjacent nitrogen atom of the acetoamido group, form a morpholino group.
Patent JP-4744053-B2 (JP)
IPC: C12Q1/689
Filed: 1999-12-17
Granted: 2011-08-10
Abstract: Oligonucleotides used to prime in vitro nucleic acid amplification of 16S rRNA sequences or DNA encoding 16S rRNA sequences for many species within the genus    Mycobacterium     are disclosed. Kits including such oligonucleotides are disclosed. Methods of detecting    Mycobacterium     species using the oligonucleotides in in vitro nucleic acid amplification are disclosed.
Patent JP-4718744-B2 (JP)
IPC: C01G23/07
Filed: 2001-02-09
Granted: 2011-07-06
Abstract: A process for controlling the formation of TiO2 particles in a multi-stage vapor-phase oxidation reactor wherein the process includes the steps of limiting the fraction of TiCl4 converted into TiO2 in the reaction stream of a first or intermediate stage of the reactor under conditions that control the mean residence time distribution of the reacting mass. By running the reaction in this manner, the growth of TiO2 particles produced is so controlled that after subsequent standard finishing steps (e.g. milling) the fraction of particles having an average size of less than 0.5 mum is reduced or minimized.
Patent JP-4355465-B2 (JP)
IPC: G06Q10/00
Filed: 2001-03-23
Granted: 2009-11-04
Abstract: The invention is characterized in comprising: a network (1); a server connected to the network (30); and user side equipment (101) for presenting advertisements to a user while transferring data with the server via the network. Moreover, there is further provided a server (20) for delivering the advertisements to the user side equipment.
Patent JP-4895457-B2 (JP)
IPC: A61K45/00
Filed: 2001-04-18
Granted: 2012-03-14
Abstract: A water soluble, biodegradable reverse thermal gelation system comprising a mixture of at least two types of tri-block copolymer components is disclosed. The tri-block copolymer components are made of a hydrophobic biodegradable polyester A-polymer block and a hydrophilic polyethylene glycol B-polymer block. The drug release and gel matrix erosion rates of the biodegradable reverse thermal gelation system may be modulated by various parameters such as the hydrophobic/hydrophilic component contents, polymer block concentrations, molecular weights and gelation temperatures, and weight ratios of the tri-block copolymer components in the mixture.
Patent JP-4927291-B2 (JP)
IPC: C12N15/02
Filed: 2001-05-18
Granted: 2012-05-09
Abstract: The present invention described and shown in the specification and drawings provides novel recombinant DT-based immunotoxins, and, more specifically anti-T cell immunotoxin fusion proteins. Also provided are immunotoxins that can be expressed in bacterial, yeast, or mammalian cells. The invention also provides means for expression of the immunotoxin fusion protein. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.
Patent JP-4191946-B2 (JP)
IPC: F16J15/06
Filed: 2002-04-03
Granted: 2008-12-03
Abstract: The invention pertains to a seal element (1) for sealing a gas-path leakage-gap (5) between spaced apart first and second components (2,3) of a turbo machinery (22), which first and second components (2,3) having opposing inner and outer surfaces (9,10) situated outside the leakage-gap (5). The seal element (1) comprises a generally gas impervious sealing member (4) and a layer (6) comprising ceramic fibres. The layer (6) covers at least partially said sealing element (1) and defines a sealing surface (21) for contacting outside the gap (5) the outer surfaces (10) of the first and second components (2,3) of the turbo machinery (22). The inventions further pertains to a combustion turbine (22), which comprises plurality of components (2,3) disposed in axial and circumferential direction, said components including guide-blade plates (12) of guide blades (16) and wall components (13), which are spaced apart in the circumferential direction or the axial direction by a leakage-gap (5) sealed off by a seal element (1). <IMAGE>
Patent JP-4215471-B2 (JP)
IPC: B67D1/04
Filed: 2002-09-13
Granted: 2009-01-28
Abstract: The container (1) has a cylindrical lower sidewall (11) and a floor (30) which define a lower beverage chamber (2), and a cylindrical upper sidewall (9) and a top wall (31) which define an upper pressurized gas chamber (3). A lower protective ring (7) is fitted around the floor, while an upper protective ring (8) is fitted around the top wall, to facilitate stacking of the containers. A partition (10), which has an outer edge welded to the upper sidewall lower edge and the lower sidewall top edge, is set between the beverage chamber and the pressurized gas chamber. A valve assembly (4), which includes a riser tube (32) that extends through the partition into the beverage chamber, is installed at the top wall. A tap (25) is connected to the valve assembly.
Patent JP-4063048-B2 (JP)
IPC: G10L21/01
Filed: 2002-10-30
Granted: 2008-03-19
Abstract: <P>PROBLEM TO BE SOLVED: To provide a reproducing device capable of starting the synchronous reproduction of performance data at a correct timing for the voice data of the same musical piece of different start time point and end time point, and to provide a reproduction method and program.  <P>SOLUTION: A controller part 6 reproduces the performance data recorded in SMF (Standard MIDI File) read from an FD drive 2 simultaneously with the reproduction of the voice data transmitted from a music CD drive 1. In the SMF, temporal information indicating the start time point and end time point of the musical piece in the voice data is recorded. In the case that there is a time deviation between the reproduction of the voice data and the reproduction of the performance data, a user supplies an adjustment instruction for the start time point and end time point of the performance data to the controller part 6 by using an operation display part 5. The controller part 6 changes the temporal information indicating the start time point and end time point of the musical piece recorded in the SMF according to the adjustment instruction supplied from the user, and adjusts the reproducing timing of the performance data by using the changed temporal information.  <P>COPYRIGHT: (C)2004,JPO
Patent JP-4393063-B2 (JP)
IPC: G03F1/00
Filed: 2000-11-28
Granted: 2010-01-06
Abstract: Techniques are provided for extending the use of phase shift techniques to implementation of masks used for complex layouts in the layers of integrated circuits, beyond selected critical dimension features such as transistor gates to which such structures have been limited in the past. The method includes identifying features for which phase shifting can be applied, automatically mapping the phase shifting regions for implementation of such features, resolving phase conflicts which might occur according to a given design rule, and application of sub-resolution assist features within phase shift regions and optical proximity correction features to phase shift regions. Both opaque field phase shift masks and complementary binary masks defining interconnect structures and other types of structures that are not defined using phase shifting, necessary for completion of the layout of the layer are produced.
Patent JP-3619824-B2 (JP)
IPC: B01D17/04
Filed: 2001-09-07
Granted: 2005-02-16
Abstract: A process for separating an aqueous emulsion including an aqueous phase and an non-aqueous phase into separated aqueous and non-aqueous phases, to provide a recovered non-aqueous phase, and to provide a recovered aqueous phase containing an acceptable level of the non-aqueous phase. In the process, at least one body, and preferably two or more bodies, of polymeric material with a high surface area, typically a foam material or polymer chips, is used in a horizontal flow treatment system to break the emulsion and thus provide both the aqueous and non-aqueous phases as two separate flows. A wide range of polymers can be used in the system as the polymeric material including polyurethane, polypropylene, polystyrene, polyester, and polyethylene. If a very low level of non-aqueous phase in the effluent is required, for example to meet potable water standards, then a Kozlowski polyurethane, as described in U.S. Pat. No. 5,239,040, is preferred as the last Polymeric material body.
Patent JP-4292005-B2 (JP)
IPC: B01J23/00
Filed: 2001-09-07
Granted: 2009-07-08
Abstract: The present invention relates to a composite of cerium, zirconium and samarium components, a catalyst composition containing such composite and the use of the catalyst composition for the treatment of a gas stream to reduce contaminants contained therein. The catalyst composition has the capability of substantially simultaneously catalyzing the oxidation of hydrocarbons and carbon monoxide and the reduction of nitrogen oxides.
Patent JP-4374562-B2 (JP)
IPC: C13B20/16
Filed: 2001-12-28
Granted: 2009-12-02
Abstract: The invention relates to a process of producing a xylose solution from a biomass hydrolysate by subjecting the biomass hydrolysate to nanofiltration and recovering as the nanofiltration permeate a solution enriched in xylose. The biomass hydrolysate used as starting material is typically a spent liquor obtained from a pulping process.
Patent JP-5154732-B2 (JP)
IPC: A61K31/57
Filed: 2002-02-05
Granted: 2013-02-27
Abstract: There is described a bimodal pharmaceutical composition comprising effective amounts of a first active ingredient which substantially comprises a coarse fraction and a second active ingredient which substantially comprise a fine fraction characterized in that the coarse fraction possesses a greater mass median aerodynamic diameter than the fine fraction. There is also described a method of delivering a therapeutically effective amount of a substantially fine active ingredient to the lung of a patient by co-administration with a substantially coarse active ingredient.
Patent JP-3793511-B2 (JP)
IPC: F16D65/18
Filed: 2003-02-05
Granted: 2006-07-05
Abstract: <P>PROBLEM TO BE SOLVED: To compatibly realize the operation feeling of a parking brake mechanism and the braking force, and to easily route cables to operate the parking brake mechanism.  <P>SOLUTION: In a disk brake device with a parking brake mechanism, a lever shaft 22 having a lever 24 connected to an operation cable is rotatably provided on a caliper arm 15a of a brake caliper 15 to convert the rotation of the lever shaft 22 into the thrust of a piston 18 via a cam mechanism 35 and a relay piston 32, and friction pads 12 and 13 are pressed against a brake disk 11 by the thrust of the piston 18 to generate the braking power. The axis L2 of the lever shaft 22 is orthogonal to the axis L1 of the piston 18, and the cam mechanism 35 is constituted of a cam groove 22d formed in an outer circumferential surface of the lever shaft 22, a cam groove 32a formed in an end face of a relay member 32, and a roller 34 abutted on the cam grooves 22d and 32a.  <P>COPYRIGHT: (C)2004,JPO&NCIPI
Patent JP-4308573-B2 (JP)
IPC: B62D21/00
Filed: 2003-05-13
Granted: 2009-08-05
Abstract: The front axle component (1) has a frame provided by cross struts (3,4) extending between 2 side.struts (2), the front cross strut having forwards projecting supports (5) to which a stabiliser (6) is attached via fixing clamps (9). Each fixing clamp has a clamp shell fitting over the stabiliser and fixing screws (12,13) for securing it to the support, with its front end designed for absorbing impact energy in a crash situation.
Patent JP-4390489-B2 (JP)
IPC: A61N5/10
Filed: 2003-07-11
Granted: 2009-12-24
Abstract: An urethral probe device for treatment of prostate hyperplasia comprises an elongated tube (12) extending between a distal end (12c) and a proximal end (12a) to be inserted into the urethra towards the prostate. A catheter probe (11) having an elongated body with a circumferential surface, a distal end (11c) and a proximal end (11a) is movably accomodated within the urethral probe. The elongated body has a longitudinal bore (11b) extending from the distal end towards an outlet opening (11d) in the circumferential surface near the proximal end. A catheter tube (13) having a distal end and a proximal sharp end (13a) is inserted with its sharp end through the longitudinal bore, the outlet opening and through the urethral wall into the prostate. The catheter tube includes means for delivering a certain pre-planned amount of radiation energy to at least one location within the prostate for effecting radiation treatment. The urethral probe allows a quick and more accurate positioning of the catheter probe and the catheter tube relative to the prostate without discomforting the patient. <IMAGE>
Patent JP-4170909-B2 (JP)
IPC: C07C265/10
Filed: 2002-10-17
Granted: 2008-10-22
Abstract: In a process for preparing isocyanates by reacting the corresponding primary amines with phosgene in an inert solvent, use is made of from 0.01 to 50 mol % of a phosphine oxide, based on the total amount of primary amine and isocyanate formed in the reaction solution.
Patent JP-4038180-B2 (JP)
IPC: D06F25/00
Filed: 2003-01-09
Granted: 2008-01-23
Abstract: Door including a hinge assembly, an inner frame and an outer frame joined together at least one thereof is connected to the hinge assembly, a transparent door glass having an edge positioned between, and fixed to, the inner frame and the outer frame, and a handle formed in a form of a recess so that fingers are put into the outer frame from an exterior and pulling the outer frame, thereby forming the handle not projected from the outer frame, to is useful to a drum type washing machine or clothes drier.
Patent JP-4565840-B2 (JP)
IPC: G06F21/34
Filed: 2003-02-12
Granted: 2010-10-20
Abstract: Apparatus and method are disclosed for digital authentication and verification. In one embodiment, authentication involves storing a cryptographic key and a look up table (LUT), generating an access code using the cryptographic key; generating multiple parallel BPSK symbols based upon the access code; converting the BPSK symbols into multiple tones encoded with the access code using the LUT; and outputting the multiple tones encoded with the access code for authentication. In another embodiment, verification involves receiving multiple tones encoded with an access code; generating multiple parallel BPSK symbols from the multiple tones; converting the BPSK symbols into an encoded interleaved bit stream of the access code; de-interleaving the encoded interleaved bit stream; and recovering the access code from the encoded de-interleaved bit stream.
Patent JP-4598401-B2 (JP)
IPC: A61K48/00
Filed: 2003-02-28
Granted: 2010-12-15
Abstract: A method of inhibiting endothelial cell proliferation in a mammal is provided. The method comprises the step of administering to the mammal an effective immunological response eliciting amount of a DNA composition comprising a DNA construct operably encoding a VEGF receptor polypeptide and a pharmaceutically acceptable carrier therefor, whereby said mammal exhibits an immune response elicited by vaccine and specific to proliferating endothelial cells. The methods of this invention inhibit vascular endothelial cell proliferation in the tumor micro-environment. Angiogenesis inhibition and subsequent decrease in tumor growth and dissemination is achieved.
Patent JP-3936339-B2 (JP)
IPC: A61K47/48
Filed: 2004-01-21
Granted: 2007-06-27
Abstract: Modified antibodies are disclosed which have been modified by chemical conjugation with a heterobifunctional reagent, such as SPDP. The use of these modified antibodies in the preparation of compositions for the diagnosis and therapy of cancer and other mammalian disease is also disclosed. These diagnostic uses include immunoscintography. The modified antibodies can be further conjugated with labels or biologically active molecules for use in such diagnosis and therapy.
Patent JP-5019703-B2 (JP)
IPC: B32B1/08
Filed: 2004-10-18
Granted: 2012-09-05
Abstract: Multilayer tube for medical purposes, free of PVC and with improved security of peeling, comprises at least 3 layers: a base layer (A), bonded to a connector layer (B) through an intermediate buffer layer (C), each made of different polymers. The tube can be formed into crinkles or loops with diameter up to 50 mm without cracking. - Multilayer tube for medical purposes, free of PVC and with improved security of peeling, comprises at least 3 layers: a base layer (A), bonded to a connector layer (B) through an intermediate buffer layer (C), each made of different polymers. The tube can be formed into crinkles or loops with diameter up to 50 mm without cracking. The new feature is that both (A) and (B) contain at least 25wt.% (on total weight of the layers) of polyolefins (I), while (C) contains over 75wt.% (of its total weight) of a thermoplastic elastomer (II) that is not a polyolefin. An INDEPENDENT CLAIM is also included for a method for preparing the new tube.
Patent JP-4503437-B2 (JP)
IPC: F01L9/10
Filed: 2003-07-30
Granted: 2010-07-14
Abstract: The present invention relates to an electrically operated valve ( 10 ), which has a valve housing ( 11 ); a spool ( 12 ); a first fluid conduit ( 14 ) connecting the valve ( 10 ) with a source of pressurized fluid; a second fluid conduit ( 15 ) connecting the valve ( 10 ) with a reservoir of fluid; and a third fluid conduit ( 16 ) in communication with valve ( 10 ) which delivers fluid to or receives fluid from apparatus which uses the hydraulic fluid flow controlled by the valve ( 10 ). The spool ( 12 ) is biased to a rest position by a pair of opposed springs ( 17,18 ) and in the rest position closes off the first ( 14 ) and second ( 15 ) fluid conduits. A first electric coil ( 19 ) associated with a first end of the spool ( 12 ) when activated displaces the spool ( 12 ) to open the first fluid conduit ( 14 ). A second electric coil ( 20 ) associated with a second end of the spool ( 12 ) when activated displaces the spool ( 12 ) to open the second fluid conduit ( 15 ).
Patent JP-4279786-B2 (JP)
IPC: H01L21/48
Filed: 2003-04-22
Granted: 2009-06-17
Abstract: The rear (1b) of a semiconductor substrate (1) is fixed to the support face (11a) of a substrate support base (11) by vacuum clamping. The thickness of the semiconductor substrate (1) is uniform by planarizing the rear (1b), and the rear (1b) is forcedly free of waviness caused by the vacuum clamping to the support face (11a), so that the rear (1b) functions as the reference face of the planarization of the front (1a). In this state, Au projections (2) on the front (1a) and the surface layer of a resist mask (12) is cut with a single point tool (10) to planarize the surface of Au projections (2) and that of the resist mask (12) so as to be flat continuously. Thus, instead of CMP, the surface of a fine bump formed on a substrate is planarized at low cost low costly and speedily.