baber/WOPTO huggingface dataset:
Patent AU-2016319131-A1 (AU)
Title: Multi-transgenic pig for xenotransplantation
Inventor: AYARES DAVID L
IPC: C12N5/16
Filed: 2016-09-09
Abstract: The present invention is directed to transgenic animals (e.g., transgenic porcine animals) comprising multiple genetic modifications that advantageously render these animals suitable donors for xenotransplanation. The present invention extends to organs, organ fragments, tissues and cells derived from these animals and their therapeutic use. The present invention further extends to methods of making such animals. In certain embodiments, the transgenic animals (e.g., transgenic porcine animals) lack expression of alpha gal and incorporate and express at least four transgenes under the control of at least two promoters.
Patent AU-2016327461-A1 (AU)
Title: Suppressors of premature termination codons as therapeutics and methods for their use
Inventor: ROBERGE MICHEL
IPC: A61P35/00
Filed: 2016-09-23
Abstract: This invention discloses the use of aminoglycoside antibiotics such as gentamicin Bl to suppress premature termination codons during translation and promote the full length read-through of transcripts such as p53 that incorporate nonsense mutations and to treat disease conditions such as cancer caused by such genetic mutations.
Patent AU-2016330046-A1 (AU)
Title: Apparatus and method for electron irradiation scrubbing
Inventor: MICHAN JUAN MARIO
IPC: B01D53/60
Filed: 2016-10-03
Abstract: The present disclosure relates to methods of scrubbing of gas by exposure to electrons and apparatuses therefor. Such methods and apparatuses could be used to reduce harmful emissions created by the burning of fossil fuels, e.g. to power ships. According to one aspect there is provided apparatus for electron irradiation scrubbing, said apparatus comprising: an anode; a cathode a nanostructure located between said anode and said cathode, said nanostructure being configured to field-emit electrons in response to the presence of an electric field between the anode and cathode when a potential difference is established therebetween; and a housing coupled to said nanostructure and configured for locating the nanostructure so that it extends into a container containing gas to be scrubbed such that an interior of said container can be exposed to said electrons. According to further aspects there are provided systems comprising such apparatus and methods making use of it.
Patent AU-2016349632-A1 (AU)
Title: Compositions comprising tumor suppressor gene therapy and immune checkpoint blockade for the treatment of cancer
Inventor: SOBOL ROBERT E
IPC: A61K39/395
Filed: 2016-11-07
Abstract: Provided herein are methods and compositions for treating cancer in an individual comprising administering to the individual an effective amount of at least one immune checkpoint inhibitor and a p53 and/or MDA-7 (IL24) gene therapy. Also provided herein are methods of enhancing anti-tumor efficacy by administering an extracellular matrix-degrading protein. Also provided herein are methods of enhancing anti-tumor efficacy by administering metronomic chemotherapy (for agents described above, 5FU+CTX+GM-CSF) in combination with a p53 and/or IL24 gene therapy.
Patent AU-2016361668-A1 (AU)
Title: MMP-sensitive taxane prodrug
Inventor: LOADMAN PAUL
IPC: A61P35/00
Filed: 2016-11-29
Abstract: The present invention harnesses the differential expression of membrane-type matrix metalloproteinases (MT-MMPs) between human solid tumours and normal tissues to provide a systemically inactive prodrug which is selectively activated at the tumour micro-environment. The present invention provides a prodrug which is a conjugate of a taxane and a selective MT-MMP cleavable delivery vehicle.
Patent AU-2016365724-A1 (AU)
Title: Microfluidic devices and kits and methods for use thereof
Inventor: BEAUMONT KRISTIN G
IPC: B01L3/00
Filed: 2016-12-07
Abstract: In situ-generated microfluidic capture structures incorporating a solidified polymer network, methods of preparation and use, compositions and kits therefor are described. Microfluidic capture structures may be advantageously used for assays performed within the microfluidic environment, providing flexibility in assaying micro-objects such as biological cells. Assay reagents and analytes may be incorporated within the microfluidic capture structures.
Patent AU-2016365824-A1 (AU)
Title: Fluidic systems involving incubation samples and/or reagents
Inventor: HADDAD DOUGLAS M
IPC: B01L3/00
Filed: 2016-12-08
Abstract: Fluidic devices and methods involving incubation and/or mixing of assay components are provided. In some embodiments, a biological and/or chemical assay may be performed in a fluidic device. The fluidic device may be designed to allow for controlled incubation and/or mixing of two or more assay components. In some such embodiments, the fluidic device may comprise an incubation channel having a relatively large cross-sectional dimension in fluid communication with a detection channel. The incubation channel may allow for adequate mixing and/or incubation of two or more assay components prior to analysis of the assay. In some embodiments, fluidic devices for performing a vitamin D assay are provided.
Patent AU-2017200542-A1 (AU)
Title: Method and system for operating an autonomous energy supply network
Inventor: FRÖHNER WIEBKE
IPC: H02J3/00
Filed: 2017-01-27
Abstract: Method and System for Operating an Autonomous Energy Supply Network Abstract The invention relates to a method for operating an autonomous energy supply network (11) which comprises a number of energy producers (15) and a number of energy consumers (16), wherein a local control device (18) which is adapted to drive the energy producers (15) and/or the energy consumers (16) is provided. In order to reduce the parameterization outlay required for the operation of the autonomous energy supply network, it is proposed for the following steps to be carried out during the method: provision of model data of the autonomous energy supply network (11) in a data memory of a computing device (20) superordinate to the local control device (18), the model data specifying the respective energy producers (15) and their operating parameters; determination of an operating plan for the autonomous energy supply network (11) with the computing device (20) by using the model data, the operating plan specifying the operating state of the autonomous energy supply network (11) during a particular time interval; transmission of the operating plan to the local control device (18); and driving of the energy producers (15) and/or the energy consumers (16) according to the specifications of the operating plan by the local control device (18). The invention also relates to a corresponding system for operating an autonomous energy supply network. Figure 2 a a a 18a 215a 20 21 22 11 la 12a 23 18b c l 12b
Patent AU-2017201765-A1 (AU)
Title: Load position display indicator for an excavation system
Inventor: GUY CHRISTOPHER JAMES
IPC: G01G19/08
Filed: 2017-03-15
Abstract: Abstract LOAD POSITION DISPLAY INDICATOR FOR AN EXCAVATION SYSTEM A load position indicating system includes a portable, stand-alone computing device (32) for use on the loader (12). The stand-alone computing device (32) includes a display, a wireless communication interface (26) configured for peer-to-peer direct communication with an electronic control unit (ECU) (18) mounted onboard the hauler (10), and at least one controller configured to receive a signal indicative of a real time position of an actual center of gravity of a payload carried by the hauler (10), determine a real time position and orientation of the loader (12) relative to the hauler (10), determine a target location for the center of gravity of the payload carried by the hauler (10), calculate a new loading position for a payload to be deposited by the loader (12) onto the hauler (10) based on a difference between the real time position of the actual center of gravity of the payload and the target location of the center of gravity, and display at least one of the new loading position for a payload, the target location for the center of gravity of the payload, and the real time position of the actual center of gravity of the payload on an image representative of the hauler (10) as seen from a perspective of an operator on the loader (12). C13) C') ~ ri C/I -I cy-) riJ F- O w 1 olWf COCI II o F ow CL =WU =D F- CO tCL Z~ C3 o 0 L 01 vi' ~4t 4r
Patent AU-2017202090-A1 (AU)
Title: Inspectable black glass containers
Inventor: SMITH ROGER P
IPC: G01N33/38
Filed: 2017-03-29
Abstract: Abstract of the Disclosure A soda-lime-silica glass container (10) related methods of manufacturing. A black-strikable glass composition having a base glass portion and a latent colorant portion is prepared. The base glass portion includes soda-lime-silica glass materials and one or more blue colorant materials, and the latent colorant portion includes cuprous oxide (Cu 2O), stannous oxide (SnO), bismuth oxide (Bi2O3), and carbon (C). Glass containers may be formed from the black-strikable glass composition, and these glass containers may be heated to a temperature greater than 600 degrees Celsius to strike black therein. The glass containers formed from the black-strikable glass composition may be inspected-before or after striking-by infrared inspection equipment.
Patent AU-2017202488-A1 (AU)
Title: Treatment or prophylaxis of proliferative conditions
Inventor: EVERETT STEVEN ALBERT
IPC: A61K31/352
Filed: 2017-04-18
Abstract: H:\iarlnicnvoven\NRPonbl\DCCAAR\5}6599 I_1.DOC- /{)4/20 13 The invention relates to novel compounds for use in the treatment or prophylaxis of cancers and other proliferative conditions that are, for example, characterized by cells that express cytochrome P450 1B1 (CYPiB1) and allelic variants thereof The invention also provides pharmaceutical compositions comprising one or more such compounds for use in medical therapy, for example, in the treatment of prophylaxis of cancers or other proliferative conditions, as well as methods for treating cancers or other conditions in human or non-human animal patients. The invention also provides methods for identifying novel compounds for use in the treatment of prophylaxis of cancers and other proliferative conditions that are, for example, characterized by cells that express CYPiBI and allelic variants thereof The invention also provides a method for determining the efficacy of a compound of the invention in treating cancer.
Patent AU-2017203337-A1 (AU)
Title: Protuberant aneurysm bridging device and method of use
Inventor: STRAUSS BRIAN M
IPC: A61F2/04
Filed: 2017-05-18
Abstract: PROTUBERANT ANEURYSM BRIDGING DEVICE AND METHOD OF A method of placing an endoluminal support, said method comprising the steps of advancing the endoluminal support within a catheter (2) in a collapsed configuration; placing the endoluminal support within vasculature of a patient to permit a distal end portion of the support to expand from the collapsed configuration to an expanded configuration; securing the distal end portion of the endoluminal support within the vasculature in the expanded configuration; after the distal end portion is secured, manipulating a proximal end portion of the endoluminal support to deform a central region of the endoluminal support; and securing the proximal end portion of the endoluminal support within the vasculature to maintain the central region of the endoluminal support in a deformed state.
Patent AU-2017208219-A1 (AU)
Title: Generating a domain ontology using word embeddings
Inventor: PODDER SANJAY
IPC: G06F17/28
Filed: 2017-07-24
Abstract: One or more devices for processing a text, the one or more devices, including one or more processors that generate a set of word vectors from a list of terms determined from another text using a vector model associated with generating the set of word vectors, wherein each word vector is a numerical representation of a term, determine a quantity of term clusters, to be generated to form an ontology of terms in the other text, based on the set of word vectors and using a statistical technique based on error measurements associated with a clustering technique, generate term clusters, representing concepts of the ontology of terms, based on the quantity of term clusters and using the clustering technique, and analyze, by a device of the one or more devices, the text using the term clusters. s.n s. CL :3 :3 o a) - ~co)I EO0*EE m~ Hn C10 0 0Q c 1 cn- - I, E * E Es..0 0. U) U)U)9 E E ___ 0 C)C/C/C/)*-U 'CN ~ )*:0 U)U)~~~ EFH -C) C)I >-- FF -- - -~~~cl ccC 3S-S. . . _l _ cn - 0 :3H0 @L H TOM U, U C) ). C) LIC TlU)
Patent AU-2017222210-A1 (AU)
Title: Stress reducing system and associated method
Inventor: CARLSEN HANS-PAUL
IPC: E21B19/00
Filed: 2017-02-22
Abstract: Stress reducing system and associated method for reducing stresses at a desired position in an offshore production or drilling system, the offshore production or drilling system comprising: a seabed structure, a floating structure and a riser (24) extending there between, the riser being tensioned, the riser (24) comprising at least a first part (45) and a second part (46), which second part (46) is connected to the first part (45) via a flexible connection (20) allowing an axial, angular and/or rotational movement between the first and second parts (45, 46), said stress reducing system comprises: - a first sensor (41) for real-time monitoring of stresses at the desired position, positioned at or close to the desired position (20), - an actuating system (42) arranged at the flexible connection (20, the actuating system (42) being connected to said first and second parts (45, 46), and wherein the actuating system (45, 46) is configured to apply a force to the first or second part (45, 46) when the first and second parts (45, 46) are moved out of a neutral position, - a control system (40) adapted to receive monitoring data from the first sensor (41), wherein the control system (40) is connected to the actuating system (42) and is able of providing instruction signals to the actuating system (42), wherein the control system (40), based on said monitoring data from the first sensor (41), is able to calculate a real-time set of data for control of the applied force of the actuating system (42) and instructing the actuating system (42) to act accordingly, such as to reduce the stress at said desired position.
Patent AU-2017228589-A1 (AU)
Title: Sealing device
Inventor: GOBLE JACOB A
IPC: A61B17/00
Filed: 2017-09-13
Abstract: A medical device for sealing a defect in tissue, the medical device comprising: a plurality of wound wires forming: a first eyelet, a second eyelet, a first disc member, a second disc member, and a defect-occupying portion disposed between the first disc member and the second disc member; and a sealing member in contact with the frame, the sealing member forming a first occluding member with the first disc member and a second occluding member with the second disc member configured to seal a range of defect sizes from a largest defect size to a smallest defect size that is approximately 60% of the largest defect size; and a non-metal attachment member arranged through one of the first eyelet and the second eyelet. 9484623_1 (GHMatters) P100317.AU.1 103 102 111ll
Patent AU-2017232594-A1 (AU)
Title: Method for manufacturing chemical and method for culturing microorganism
Inventor: SAWAI KENJI
IPC: C12P7/06
Filed: 2017-03-16
Abstract: Provided is a method for manufacturing a chemical by culturing a microorganism using a fermentation raw material comprising cane molasses as a main component, collecting a filtered liquid comprising the chemical in which the microorganism has been separated by filtrating a culture solution using a separation membrane, further keeping or refluxing an unfiltered liquid comprising the microorganism in the culture solution, and adding the fermentation raw material to the culture solution and performing continuous fermentation, wherein a microorganism containing a particle having an average particle diameter of 100 nm or more in the centrifuge supernatant of the culture solution is cultured.
Patent AU-2017238706-A1 (AU)
Title: Antibody capable of binding to undifferentiated germ cells of scombridae fish
Inventor: ICHIDA Kensuke
IPC: C12N5/076
Filed: 2017-03-24
Abstract: The present invention relates to a monoclonal antibody that specifically recognizes undifferentiated germ cells of scombridae fish, wherein the monoclonal antibody is an antibody against undifferentiated germ cells isolated from a testis or an ovary of scombridae fish. The present invention provides an antibody that can isolate undifferentiated germ cells of scombridae fish.
Patent AU-2017240185-A1 (AU)
Title: Photosensitive dispersion and use thereof
Inventor: KÖNIG BURKHARD
IPC: A61K6/00
Filed: 2017-03-31
Abstract: The invention relates to a photosensitizer-containing dispersion and to the use thereof.
Patent AU-2017255503-A1 (AU)
Title: Method, device, and computer-readable medium for wagering on a skills-based digital gaming competition with an out-of-game peer wagering module
Inventor: ALEKSEY RUSSELL M
IPC: A63F9/24
Filed: 2017-04-20
Abstract: A method for wagering on a skills-based digital gaming competition, the method executing on a computing device including storage storing a peer-wagering module that is external and distinct from at least one game stored on the storage device or another storage device, the method including: receiving potential game and competitor player data; receiving game competition selection information from the player that includes at least one selected game instance and at least one wager amount; receiving game instance match ID data generated by the transactional server, wherein the game instance match ID data includes at least one of: credential data associated with the player, player wager amount or a board, level, or difficulty setting associated with the selected game instance; and transmitting the game instance match ID data and game initiation data to the game, thereby activating the at least one selected game instance on the computing device.
Patent AU-2017295762-A1 (AU)
Title: Metabolic drug loading of EVs
Inventor: WIKLANDER Oscar
IPC: A61K47/66
Filed: 2017-07-10
Abstract: The present invention relates to methods for metabolically loading extracellular vesicles (EVs) with a pharmacological agent. The methods comprise culturing EV source cells in the presence of a metabolic component comprising a pharmacological agent, which is thereby incorporated into the EV-producing cells and subsequently into the EV. The invention further relates to medical uses and compositions of such EVs.
Patent AU-2017308060-A1 (AU)
Title: Devices and methods for enabling portable secure communication using random cipher pad cryptography
Inventor: MCCARTHY KEVIN R
IPC: H04L9/08
Filed: 2017-08-11
Abstract: A cryptographic system includes a host device and a cryptographic device. For encryption, the host includes an application that is configured to enable a user to compose an unencrypted message on a user interface and transmit the unencrypted message. The cryptographic device is configured to receive the unencrypted message, encrypt the unencrypted message with RCPs on a non-volatile storage to create an encrypted message, and send the encrypted message to the host, which then transmits the encrypted message through a communication channel. For decryption, the host receives an encrypted message through the communication channel and sends it to the cryptographic device. The cryptographic device decrypts the encrypted message with the RCPs and sends the decrypted message back to the host, which presents the decrypted message on a display. The cryptographic device may be configured to destroy RCPs that have been used up.
Patent AU-2017324844-A1 (AU)
Title: Tablet compositions
Inventor: BHAT SREENIVAS S
IPC: A61K9/20
Filed: 2017-09-06
Abstract: Provided herein is a tablet comprising: 2-methyl-1-[(4-[6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2-yl)amino]propan-2-ol or a pharmaceutically acceptable salt thereof.
Patent AU-2017332498-A1 (AU)
Title: Insect egg conveyor
Inventor: MASSARO PETER
IPC: A01K67/033
Filed: 2017-08-07
Abstract: Example insect egg conveyors are disclosed. One example insect egg conveyor device includes multiple rollers positioned along a path and a drive unit that includes a motor connected to a roller of the multiple rollers to drive the roller and rotate the roller. The device also includes a substrate positioned on the roller and a fluid source positioned along the path. The rollers are arranged to move the substrate along the path and toward the fluid source in response to the motor rotating the roller.
Patent AU-2017358595-A1 (AU)
Title: Josephson junction superconductor device interconnect
Inventor: KIRBY CHRISTOPHER F
IPC: H01L39/24
Filed: 2017-08-03
Abstract: The disclosed method of forming a Josephson junction (JJ) based superconductor device interconnect structure includes forming a base electrode (18) in a coplanar first dielectric layer (16), preferably by a damascene process, depositing a second dielectric layer (20) thereon, forming a first contact (22) through the second dielectric layer to a first end of the base electrode, forming a JJ (30) overlying and in contact with the first contact, and forming a second contact (24) through the second dielectric layer to a second end of the base electrode.
Patent AU-2017361460-A1 (AU)
Title: Customized surgical guide and customized surgical guide generating method and generating program
Inventor: KIM NAM KUG
IPC: A61B17/34
Filed: 2017-11-15
Abstract: The present invention relates to a customized surgical guide device and a customized surgical guide generating method and program. A customized surgical guide generating method according to another embodiment of the present invention comprises the steps of: acquiring body surface data and treatment area data from medical image data by a computer (S100); a first shape data generating step of generating first shape data on the basis of the body surface data, wherein the first shape data is data which corresponds to the shape of the body part cover (S300); a target point setting step of setting one or more target points, wherein the target point is a point which corresponds to the inside or the surface of an area to be treated (S500); setting individual first points on the body surface accessible to the target point with a medical tool (S700); setting a guide tube length on the basis of a distance from the first point to the target point (S900); and generating final shape data in which one or more guide tubes are combined to the first shape data by applying the guide tube length to the first point (S1100).
Patent AU-2017363367-A1 (AU)
Title: Robotic surgical system to reduce unwanted vibration
Inventor: TIMM RICHARD WILLIAM
IPC: A61G1/06
Filed: 2017-11-27
Abstract: A base for a surgical table, carrying optionally a patient and any equipment supportable by the surgical table, includes a base body to which other components of a surgical table can be coupled, a support assembly coupled to the base body to support the base body o the surface, and a load sensor disposed to detect the portion of the total load carried by one of the support members. The support assembly includes at least four support members, each having a surface-engaging end. One of the support members is adjustable to move the one support member relative to a plane defined by the three of the other support members and thereby to change the portion of the total load carried by one of the support members.