baber/WOPTO huggingface dataset:
Patent CA-2543142-A1 (CA)
Title: Methods and compositions for identifying therapeutic compounds
Inventor: MCDERMOTT MARTIN
IPC: A61K31/7076
Filed: 2004-10-22
Abstract: By the present invention, enzymes responsible for prodrug activation are identified and utilized for the identification of candidate compounds as prodrugs. The present invention includes methods for identifying a candidate compound as a suitable prodrug as well as methods of screening candidate compounds for suitability as therapeutic agents.
Patent CA-2543367-A1 (CA)
Inventor: D ALLESSANDRO ROBERT
IPC: C10G67/04
Filed: 2004-10-20
Abstract: The present disclosure is directed to a multi-stage system and a process utilizing said system with the design of reducing the sulfur-content in a liquid comprising hydrocarbons and organosulfur compounds. The process comprising at least one of the following states: (1) an oxidation stage; (2) an extraction state; (3) a raffinate washing stage; (4) a raffinate polishing stage; (5) a solvent recovery stage; (6) a solvent purification stage; and (7) a hydrocarbon recovery stage. The process for removing sulfur-containing hydrocarbons from gas oil, which comprises oxidizing gas oil comprising hydrocarbons and organosulfur compounds to obtain a product gas oil.
Patent CA-2544074-A1 (CA)
Title: Method for the identification and/or validation of receptor tyrosine kinase inhibitors
Inventor: BARBERIS ALCIDE
IPC: C12Q1/48
Filed: 2003-10-24
Abstract: An in vivo method for the identification and/or validation of receptor tyrosine kinase inhibitors is described. Said method is characterised by the following steps: a) providing host cells comprising a nucleic acid construct encoding a peptide which comprises a tyrosine kinase domain of a receptor tyrosine kinase wherein said peptide lacks a transmembrane domain or a functional fragment thereof and said tyrosine kinase activity in the cytoplasma leads to proliferation arrest, b) contacting said host cells with a candidate compound and c) identification of inhibitors of said tyrosine kinase activity by cultivation of said host cells under suitable conditions such that the modulation of the tyrosine kinase activity by the candidate compound leads to cell growth.
Patent CA-2544667-A1 (CA)
Title: Pool skimmer seal assembly
Inventor: HODAK JERRY
IPC: E04H4/16
Filed: 2006-04-12
Abstract: A seal for a pool skimmer is provided. The seal is attached to the inner periphery of the faceplate via cooperating male/female connectors on the seal and inner periphery of the faceplate at the opening for fluid passage from the pool to the skimmer housing and filter assembly. In this manner, the surface of the seal is generally flush with the faceplate. Moreover, the fasteners which secure the faceplate and the skimmer housing to the pool sidewall remain accessible for later adjustment by the pool owner or pool service personnel with the seal securely in place. The seal may include a ring tab or other member extending from the outer periphery thereof for ease of removal of the seal.
Patent CA-2544977-A1 (CA)
Title: Method and apparatus for a quick blade release folding utility knife
Inventor: WU HARRY CHING LIM
IPC: B26B1/08
Filed: 2006-04-27
Abstract: A utility knife comprising a handle, a blade holder, a slot penetrating the blade holder that is adapted to accept a blade, a recess inside the blade holder that is open to the slot, a button bore between one side of the blade holder and the slot, and a locking mechanism that has a button and a projection. The locking mechanism is configured to move between a locked position in which the projection engages and secures the blade and an unlocked position in which the locking mechanism enters the recess thereby withdrawing the projection from the slot and allowing a blade to be slidably removed from or inserted into the slot. The button on the locking mechanism is accessible through the button bore. Depressing the button moves the locking mechanism from a locked to an unlocked position thereby allowing the blade to slidably move in the slot.
Patent CA-2547716-A1 (CA)
Inventor: GRIS ALEXANDER
IPC: B01F25/60
Filed: 2004-05-10
Abstract: A mixing apparatus (21) for use with a vessel (22) having a contiguous sidewall substantially centered about and defining a longitudinal axis (A), the mixing apparatus having a base plate (25) removably mountable atop the vessel, a table frame (55) removably mountable atop the base plate and a housing (42) removably mountable atop the table frame. The apparatus also features a mixing head (30) comprising a generally annular blade body (72) for immersion into the fluids to be mixed within the vessel, the blade body having a centrally positioned hub member (70) defining a substantially vertically directed hub axis, said hub member being attached to and surrounded by a ring portion defining an orifice having a centre of symmetry. A drive shaft (84) is provided for supporting the mixing head within the vessel and extending from the hub member to the housing. A reciprocating drive assembly (40) is mounted within the housing, the reciprocating drive assembly being operatively connectable to the drive shaft for imparting reciprocating longitudinal movement to the mixing head. A linear bearing assembly (90) is mounted on the table frame in proximal relation to the housing, with the drive shaft operatively slidable within the linear bearing assembly. With this arrangement, the mixing apparatus is positionable atop the vessel with the drive shaft, hub axis and centre of symmetry all being substantially aligned with said longitudinal axis. The housing is easily removable for servicing of the apparatus without disassembly of the remainder of the assembly.
Patent CA-2548298-A1 (CA)
Inventor: HASEGAWA KOUJI
IPC: A23L1/00
Filed: 2005-07-15
Abstract: [PROBLEMS] A coating device providing excellent workability in spray nozzle installation and replacement, not having complexity in its structure, and advantageous in layout. [MEANS FOR SOLVING PROBLEMS] A rotating drum (2) is driven and rotated about an axis A inclined relative to a horizontal line and has, at one end on the upper side of the inclination, an opening (5). A spray nozzle unit (10) is removably installed on a swing arm (34), and the swing arm (34) is swingable about a swing shaft (34c). The spray nozzle unit (10) can be taken in and out between the inside and outside of the rotating drum (2) by the swing action of the swing arm (34).
Patent CA-2550580-A1 (CA)
Inventor: WANG PING T
IPC: C07J75/00
Filed: 1996-12-11
Abstract: Multiple novel reaction schemes, novel process steps and novel intermediates are provided for the synthesis of epoxymexrenone and other compounds of formula (I): (see formula I) wherein: -A-A- represents the group -CHR4-CHR5- or -CR4-CR5-;      R3, R4 and R5 are independently selected from the group consisting of hydrogen, halo, hydroxy, lower alkyl, lower alkoxy, hydroxyalkyl, alkoxyalkyl, hydroxycarbonyl, cyano, aryloxy;      R1 represents an alpha-oriented lower alkoxycarbonyl or hydroxyalkyl radical; -B-B- represents the group -CHR6-CHR7- or an alpha-or beta-oriented group of formula (III): (see formula III) wherein:     R6 and R7 are independently selected from the group consisting of hydrogen, halo, lower alkoxy, acyl, hydroxyalkyl, alkoxyalkyl, hydroxycarbonyl, alkyl, alkoxycarbonyl, acyloxyalkyl, cyano, aryloxy; and R8 and R9 are independently selected from the group consisting of hydrogen, halo, lower alkoxy, aryl, hydroxyalkyl, alkoxyalkyl, hydroxycarbonyl, alkyl, alkoxycarbonyl, acyloxyalkyl, cyano, aryloxy, or R8 and R9 together comprise a carbocyclic or heterocyclic ring structure, or R8 or R9 together with R6 or R7 comprise a carbocyclic or heterocyclic ring structure fused to the pentacyclic D ring.
Patent CA-2550877-A1 (CA)
Title: Vehicle video processing system
Inventor: ABRAHAM CLAUDE
IPC: B60R1/00
Filed: 2005-02-25
Abstract: Disclosed are various systems and methods for processing and displaying video in a vehicle. In one embodiment, a vehicle video system (101) is provided that comprises a plurality of cameras (103, 106) mounted in a vehicle (100), each of the cameras generating a video image, and the cameras including a plurality of visible light cameras (103) and a plurality of night vision cameras (106).  The vehicle video system (101) also includes a video processing unit (109), where each of the cameras and each of the monitors (113) are electrically coupled to the video processing unit (109). The video processing unit (109) being configured to select at least two subsets of the cameras from which output video images are obtained for display on monitors (113).
Patent CA-2550933-A1 (CA)
Inventor: YAN WEI
IPC: C12Q1/68
Filed: 2004-12-21
Abstract: The invention provides methods for screening multimeric antibodies produced by mammalian cells to find those that exhibit a biological function. The methods can be used to screen large numbers of antibodies, which may be cell surface, secreted, or intracellular antibodies. Antibodies can be screened to find those that bind antigen more avidly or those that compete with a ligand that binds to the antigen for binding. Any biological function that can be tested in vitro can be used to screen the antibodies. Nucleic acids encoding the antibodies that exhibit the biological function can be obtained in a number of ways.
Patent CA-2551105-A1 (CA)
Inventor: WELLINGTON SCOTT LEE
IPC: B01J23/22
Filed: 2004-12-16
Abstract: Contact of a crude feed with one or more catalysts produces a total product that include a crude product. The crude product is a liquid mixture at 25~C  and 0.101 MPa. One or more other properties of the crude product may be changed by at least 10% relative to the respective properties of the crude feed.
Patent CA-2551647-A1 (CA)
Inventor: THOMAS JAMES W
IPC: B23K26/40
Filed: 2005-01-06
Abstract: A coating removal apparatus utilizing a common optics path to provide laser pulses to a coated surface (50) and to direct a light illumination (34) reflected from the coated surface to a photosensitive detector and analyzer.  The apparatus is an integrated device including a laser source (12), a beam splitter (14), scanning optics (16), a waste removal apparatus (26), one or more light illuminators (18), a photosensitive detector (20), a comparator (22), and a control logic circuit (24). Alternatively, the laser source is external to the integrated device and a fiber optic cable is used to connect the laser source to the integrated device.
Patent CA-2552371-A1 (CA)
Inventor: KAUL SAVITA
IPC: C11C3/10
Filed: 2003-12-30
Abstract: Fatty acid alkyl esters suitable for use as biodiesel are produced by a sing le step esterification of free fatty acids and transesterification of triglycerides from vegetable oils or animal fats or combinations thereof wit h a lower alcohol (e.g. methanol) in presence of alkyl Tin oxide as catalyst. The ester thus produced is purified by distillation, treatment with an adsorbent, washing with water or combination thereof to give esters suitable for use as biodiesel.
Patent CA-2552829-A1 (CA)
Inventor: HILDEBRAND MELVIN
IPC: C08F10/02
Filed: 2005-01-05
Abstract: Polymer fractions such as polyethylene fractions can be produced that have a PDT less than 2.3 and a M,~ greater than 1,000,000 g/mol, 3,000,000 g/mol, or 6,000,000 g/mol. Such polyethylene fractions are separated from a UHMWPE  parent polymer by first dissolving the parent polymer in a relatively good solvent. The conditions employed for such dissolution are selected to reduce the degradation of the parent polymer. The resulting parent solution is transported into a fractionation column in which a support is disposed. The fractionation column is thereafter operated at conditions effective to form a precipitate on the support comprising the desired polyethylene fraction. The polyethylene fraction may then be recovered from the fractionation column by repeatedly displacing a solvent/non-solvent mixture into the column to dissolve the polyethylene fraction. The relative concentrations of the solvent and the non-solvent are based on a solvent gradient profile of the polyethylene parent polymer.
Patent CA-2558081-A1 (CA)
Title: Process of sulfating select polymers
Inventor: REILMAN RANDALL THOMAS
IPC: C07C305/10
Filed: 2005-03-17
Abstract: A process for sulfating alkoxylated amines, alkoxylated polyols, hydrophobic polyamine ethoxylate polymers, via the use of sulfuric acid.
Patent CA-2558909-A1 (CA)
Title: Technique for determining properties of earth formations using dielectric permittivity measurements
Inventor: SELEZNEV NIKITA
IPC: G01V3/30
Filed: 2006-09-07
Abstract: Techniques for determining formation characteristics use measurements of dielectric permittivity at a number of frequencies. Determined characteristics include the vertical and horizontal formation dielectric constant and conductivity, the formation water conductivity, the water saturation, the cementation and the saturation exponents. In laminated formations these profiles can be determined for each lamina. Also, formation dielectric properties are used in determination of the rock type.
Patent CA-2559920-A1 (CA)
Inventor: MCKAY STUART
IPC: H04N13/363
Filed: 2004-03-29
Abstract: A stereoscopic display (10) comprising a concave mirror (12) that acts as a directional screen, a projection system (18) including a plurality of reflecting surfaces for directing first and second images (19) onto focusing means, and a beam splitter (14) between the mirror (12) and the focusing means for directing light from the focusing means towards the mirror (12) whilst allowing light reflected from the mirror (12) to be transmitted therethrough.  In a preferred embodiment, the focusing means comprise a single lens for focusing both of the first and second images toward the concave mirror.  Ideally, a tracking system (16) is employed to detect movement of a user's head and/or eyes and move the concave mirror so that it tracks any such detected movement.
Patent CA-2559981-A1 (CA)
Inventor: BAHR LYMAN G
IPC: F42D1/04
Filed: 2000-01-19
Abstract: An initiator for a secondary explosive receptor charge is provided by forming a length of detonating cord into a helical coil containing a plurality of windings with a cut-off barrier provided by e.g., a separating rib between adjacent windings. The adjacent windings may be not more than about 0.5 inch (12, 7 mm) apart. The detonating cord may be wound about a spindle which may optionally provide the separating rib. The coil may be a tapered coil which may define a taper angle of e.g., from about 2 to 4 degrees. Alternatively, the coil may be a cylindrical coil, or the cord may be configured. in a planar spiral. Optionally, the detonating cord in the helical coil may have a core of explosive material with a loading of less than 15 grains per foot of the cord, e.g., less than 12 grains per foot of the cord, or a loading in the range of from 8 to 12 grains per foot of the cord. The coil may consume about six inches of the cord. Conversely, the detonating cord in the spiral may have a core of explosive material with a loading of at least 2.5 grains per foot, optionally at least 15 grains per foot of the cord.
Patent CA-2564786-A1 (CA)
Title: Procede de reconnaissance et de suivi de supports fibreux, ainsi que les applications d'un tel procede dans le domaine informatique notamment
Inventor: BOUTANT YANN
IPC: G07D7/00
Filed: 2005-04-06
Abstract: L'invention concerne un procédé d'acceptation d'un support fibreux candidat, en papier, carton ou non tissé, en tant que support fibreux authentique, qui comprend les étapes suivantes : comparaison de la signature numérique candidate d'un support fibreux ô au moins une signature numérique authentique d'un support fibreux authentique préalablement enregistrée sur u n support de données numériques, de façon ô émettre une décision pos itive ou négative d'acceptation, caractérisé en ce que : - les signatures numériqu es sont obtenues ô partir d'une caractéristique structurelle obtenue en scrutant un volume du support, - la comparaison détermine, selon une méthode statistique, un indice de similitude entre la signature numérique candidate et la signature numérique authentique, et compare cet indice de similitude avec un seuil d'acceptation donné, choisi pour permettre l'émission d'une décisio n positive d'acceptation dans des cas où la signature numérique candidate ne correspond pas exactement ô la signature numérique authentique ave c laquelle elle est comparée.
Patent CA-2564957-A1 (CA)
Title: Lift-off process for gan films formed on sic substrates and devices fabricated using the method
Inventor: NAKAMURA SHUJI
IPC: H01L33/00
Filed: 2005-03-22
Abstract: One embodiment of a method according to the present invention for fabricating a high light extraction photonic device comprises growing a lift-off layer on a substrate and growing an epitaxial semiconductor device structure on the lift-off layer such that the lift-off layer is sandwiched between said device structure and substrate. The epitaxial semiconductor structure comprises an emitter adapted to emit light in response to a bias. The device structure, lift-off layer and substrate is flip-chip mounted on a submount such that the epitaxial semiconductor device structure is sandwiched between the submount and lift-off layer. The lift-off layer is removed to separate the substrate from the device structure. Different removal methods can be used such as removal by a photo electrochemical etch or by illuminating the lift-off layer with laser light.
Patent CA-2566304-A1 (CA)
Title: Water compatible hydraulic fluids
Inventor: ZAZOVSKY ALEXANDER
IPC: C10M161/00
Filed: 2005-05-25
Abstract: A composition for use in an oil chamber of a tool includes a hydraulic oil;  and a surfactant, wherein the surfactant is present at an amount sufficient to form micelles in the hydraulic oil. The composition may further include an amphiphilic copolymer. A method includes providing a hydraulic fluid composition comprising a hydraulic oil and a surfactant capable of forming micelles in the hydraulic oil; and filling a hydraulic chamber in the tool with the hydraulic fluid composition. The hydraulic fluid composition may further include an amphiphilic copolymer.
Patent CA-2568034-A1 (CA)
Inventor: GRUEBER HEINZ
IPC: B29C65/48
Filed: 2005-05-25
Abstract: A device for applying a polyurethane mixture to a backstitch side of a greige includes: a tensioning roller rotatable in a first direction; an application roller arranged adjacent to the application roller and rotatable in a second direction opposite to the first direction, the tensioning roller and the application roller positioned transversely and adjacent to a path of travel of the greige on the backstitch side of the greige, the tensioning roller rotatable against a feed direction of the greige, the application roller rotatable in the feed direction of the greige; and a dispenser configured to create a puddle of the polyurethane mixture between the tensioning roller and the application roller.
Patent CA-2571390-A1 (CA)
Inventor: EVANS DARIN
IPC: B60R19/34
Filed: 2005-06-20
Abstract: A tubular bumper beam includes mounts for mounting to a vehicle frame and a crush cone in front of each mount. Each crush cone includes a flange engaging a front wall of the beam and includes a tube section extending through the front wall into engagement with a rear wall of the beam. A thermoformed energy absorber includes ridges engaging horizontal channels in the face and recesses receiving the flanges of the crush cones. The energy absorber is thermoformed to include crush boxes. At least two crush boxes include adjacent side walls having root sections bonded together near their base walls for increased strength. This is accomplished by scriving and cutting back a leading edge of one of the blade-shaped protrusions, such that the scrived leading edge leaves the root regions exposed so that the root regions bond together while the plastic material is hot.
Patent CA-2573124-A1 (CA)
Title: Anti-inflammatory medicaments
Inventor: PETILLO PETER A
IPC: A61K31/53
Filed: 2005-06-30
Abstract: Novel compounds and methods of using those compounds for the treatment of inflammatory conditions are provided. In a preferred embodiment, modulation of the activation state of p38 kinase protein comprises the step of contacting the kinase protein with the novel compounds.
Patent CA-2573432-A1 (CA)
Inventor: WOJTKIEWICZ MARK
IPC: A63H5/00
Filed: 2007-01-09
Abstract: Disclosed herein is an activity play set including an upper cabinet portion telescopically movable with respect to a lower cabinet portion. The play set is reconfigurable between a collapsed, lower configuration and an extended, higher configuration. A latch mechanism secures the upper cabinet portion in position relative to the lower cabinet portion. The latch mechanism is fixed to the lower cabinet portion and includes outwardly-biased slide members. As the upper cabinet portion and lower cabinet portion slide relative to each other, the outwardly-biased slide member ends contact and slide along slide walls of the upper cabinet portion. Furthermore, the slide walls of the upper cabinet portion include lock openings to receive the slide member ends. To release the latch mechanism to permit the upper cabinet portion to slide relative to the lower cabinet portion, the slide members are compressed inward to retract the slide member ends from the lock openings in the slide walls.
Patent CA-2574318-A1 (CA)
Title: System for providing video on demand with pause feature
Inventor: RAMAKESAVAN SUNDARAM
IPC: H04N7/16
Filed: 2000-01-10
Abstract: A system for providing video upon request may transmit encrypted video information to one or more recipients for viewing at a later time. The recipient may make a request to view one of the received video files. This request maybe provided to a video transmitter which may provide, in return, video decryption information to allow immediate viewing of the previously received video transmission.
Patent CA-2574406-A1 (CA)
Title: Method for the production of 3-phenyl(thio)uracils and dithiouracils
Inventor: GEBHARDT JOACHIM
IPC: C07D239/54
Filed: 2005-07-13
Abstract: The invention relates to a method for the production of 3-phenyl(thio)uracils and dithiouracils of formula I, wherein the variables have the meanings cited in the description, characterized in that carbamates of formula II, wherein variables X1, X3, Ar and A have the above-mentioned meanings and L1 represents a nucleophilically displaceable nucleofuge, can be reacted with enamines of formula III, wherein variables X2, R1, R2 and R3 have the above-mentioned meanings and L2 represents a nucleophilically displaceable nucleofuge. The invention also relates to intermediate products for the production thereof.
Patent CA-2575085-A1 (CA)
Inventor: BARNHART RANDY C
IPC: H04B7/185
Filed: 2006-03-16
Abstract: In one embodiment, a system for data handling in a distributed communication network includes a data-handling node (DHN) residing at a mission management center (MMC). The MMC manages operations of one or more remote units. The DHN  receives a stream of data units from a routing system. The stream of data units includes both stored mission data (SMD) and telemetry data having originated at the remote units. The DHN, in near real time, extracts the telemetry data from the stream of data units, identifies one or more subsystems of the MMC for receiving the extracted telemetry data, and communicates the extracted telemetry data to the identified subsystems of the MMC for processing.
Patent CA-2575744-A1 (CA)
Title: Iodizing agent and process for preparation thereof
Inventor: SHETH MRUNALBEN VINODRAY
IPC: C01B11/22
Filed: 2004-06-30
Abstract: A method for preparation of iodizing agent for the use in the formulation of iodised salt that offers excellent stability of iodine in iodised salt is developed and the unrefined salt iodised with this compound was tested for its stability in presence of moisture, temperature and metal salts at higher temperature. The hydrotalcite type layered compound was used to prepare such compound and part of carbonate was substituted with iodate anion. The iodising agent exhibited excellent stability of iodine in iodised salt.