baber/WOPTO huggingface dataset:
Patent JP-3775684-B2 (JP)
IPC: C07C69/773
Filed: 1993-07-28
Granted: 2006-05-17
Abstract: This invention is directed to the pharmaceutical use of phenyl compounds, which are linked to an aryl moiety by various linkages, for inhibiting tumor necrosis factor. The invention is also directed to the compounds, their preparation and pharmaceutical compositions containing these compounds. Furthermore, this invention is directed to the pharmaceutical use of the compounds for inhibiting cyclic AMP phosphodiesterase.
Patent JP-2644568-B2 (JP)
IPC: A61M5/28
Filed: 1988-07-08
Granted: 1997-08-25
Abstract: PCT No. PCT/DK88/00116 Sec. 371 Date Jan. 11, 1990 Sec. 102(e) Date Jan. 11, 1990 PCT Filed Jul. 8, 1988 PCT Pub. No. WO89/00435 PCT Pub. Date Jan. 26, 1989.Disposable hypodermic syringe comprising a needle (1) which can be retracted and held inside the syringe which moreover comprises a syringe barrel (4, 5) with liquid chamber designed with a piston (14) with a piston rod (7). Opposite the piston (14) the liquid chamber has an entirely or partially yielding end wall (6) with an opening, and the needle (1) is in its end area opposite its point provided with a head (3) which is subjected to the pressure of a spring in the direction toward the yielding wall (6). The piston (14) has a projection with locking means (10) designed to interlock with the opening in the yielding wall (6) when the piston bottoms in that the needle simultaneously snaps into a cavity (9) in the piston through the opening in the yielding wall (6); further usage of the syringe is hereby prevented.
Patent JP-2937477-B2 (JP)
IPC: C23C4/12
Filed: 1991-04-18
Granted: 1999-08-23
Abstract: PCT No. PCT/GB91/00606 Sec. 371 Date Nov. 12, 1992 Sec. 102(e) Date Nov. 12, 1992 PCT Filed Apr. 18, 1991 PCT Pub. No. WO91/16471 PCT Pub. Date Oct. 31, 1991.A method for the spray distribution of metals includes emitting a stream of molten metal particles and a gas nozzle which is rotated about the stream. The gas nozzle is inclined to the axis of the particle stream and in the direction of the stream in order to produce a required distribution of the particle stream on a workpiece.
Patent JP-3474576-B2 (JP)
IPC: C12N1/20
Filed: 1994-09-02
Granted: 2003-12-08
Abstract: PCT No. PCT/DK94/00331 Sec. 371 Date Feb. 14, 1996 Sec. 102(e) Date Feb. 14, 1996 PCT Filed Sep. 2, 1994 PCT Pub. No. WO95/07350 PCT Pub. Date Mar. 16, 1995A protease obtained from Bacillus sp., DSM 8473, is disclosed which has improved hypochlorite stability as compared to other known proteases. The protease is suitable as a detergent additive and may be used singly or combined with other know enzymes in detergent compositions. A process for washing soiled fabric with detergent compositions containing the hypochlorite stable protease is also disclosed.
Patent JP-H0466616-B2 (JP)
IPC: B08B3/02
Filed: 1988-10-13
Abstract: PCT No. PCT/SE88/00532 Sec. 371 Date Apr. 3, 1990 Sec. 102(e) Date Apr. 3, 1990 PCT Filed Oct. 13, 1988 PCT Pub. No. WO89/03251 PCT Pub. Date Apr. 20, 1989.The internal cleaning of a centrifuge rotor is performed by a cleaning liquid is which pumped from a tank via an inlet channel to a central inlet chamber of the rotor during rotation thereof. A separation chamber is connected to the inlet chamber and, at different radial levels, to two outlet chambers via separate outlet passages. Cleaning liquid is discharged from the outlet chambers through a stationary discharge device having separate outlet channels. Part of the cleaning liquid discharged through the outlet channels is returned to the tank via a return conduit. The rest of the cleaning liquid is conducted directly to the inlet channel by means of an overpressure generated in the stationary discharge device. Thereby, it is possible to clean the rotor internally even very close to its rotational axis.
Patent JP-3372250-B2 (JP)
IPC: A61M29/02
Filed: 1991-05-06
Granted: 2003-01-27
Abstract: An apparatus is described for selectively inducing the permeation of a liquid to a region of a stenosis in a blood vessel in a patient's body. The apparatus includes an external electrode (13) for positioning outside the patient's body and a catheter (10) carrying an internal electrode (38) for positioning adjacent a stenosis in a blood vessel in the body. The apparatus includes means for inducing an electric field between the internal electrode (38) and the external electrode (13) which is pulsed in phase with the patient's cardiac rhythm. <IMAGE>
Patent JP-2694049-B2 (JP)
IPC: G01N23/04
Filed: 1992-05-14
Granted: 1997-12-24
Abstract: The invention relates to nondestructive testing of internal structure of objects. A method for obtaining internal structure image of an object consists in collimation of the penetrating radiation flow from a source (1) by means of a monocrystal- monochromator (4), subjecting the object (7) to the collimated radiation, collimation of the radiation penetrated through the object by means of a monocrystal (8) and recording of said radiation by means of a detector (9). According to the invention the object is exposed to the asymmetrical reflection of the radiation from the crystal-monochromator (4) and a pseudoflat beam (5) is formed with a wide wave front and with a divergence in the plane of Bragg diffraction at least twice lower than the interval width of Bragg reflection of the monocrystal (8). The latter is oriented in the position of Bragg reflection in relation to the pseudoflat beam (5) formed by the monocrystal-monochromator (4). The method is intended, in particular for diagnostics of polymer and ceramic objects as well as for medical diagnostics. <IMAGE>
Patent JP-3888643-B2 (JP)
IPC: C12P21/08
Filed: 1993-11-04
Granted: 2007-03-07
Abstract: Humanized antibodies are described which are specific to an Fc receptor (FcR). The humanized antibodies have at least a portion of a complementarity determining region (CDR) derived from a non-human antibody, e.g., murine, with the remaining portions being human in origin. The humanized antibodies can be used therapeutically as is or formulated as bifunctional molecules or immunotoxins.
Patent JP-3009924-B2 (JP)
IPC: A61K47/00
Filed: 1993-12-06
Granted: 2000-02-14
Abstract: Stabilized medicinal aerosol solution formulations comprising medicaments that degrade or decompose by interaction with solvents or water, an HFC propellant, a cosolvent and an acid are described. Further, specific medicinal aerosol solution formulations comprising ipratropium bromide or fenoterol, ethyl alcohol, 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoropropane, and either an inorganic acid or an organic acid are described. The acids are present in amounts sufficient to reduce the degradation of the medicaments to acceptable levels.
Patent JP-3594311-B2 (JP)
IPC: A61K31/535
Filed: 1994-12-02
Granted: 2004-11-24
Abstract: New and known 5-Ä(2H-pyrrol-2-ylidene)methylÜ-2,2'-bi-1H-pyrrole derivatives, having immunomodulating activity and, represented by the following general formula (I) <CHEM> wherein, subject to a proviso, R1 represents hydrogen, phenyl, C1-C20 alkyl or C2-C20 alkenyl, wherein the alkyl and alkenyl groups may be unsubstituted or substituted by 1 to 3 substituents chosen independently from halogen, C1-C6 alkoxy, hydroxy, aryl and aryloxy; R2 represents hydrogen, C1-C6 alkyl, cyano, carboxy or (C1-C6 alkoxy) carbonyl; R3 represents halogen, hydroxy or C1-C11 alkoxy unsubstituted or substituted by phenyl; R4 represent hydrogen, C1-C6 alkyl or phenyl; each or R5 and R6 independently represents hydrogen, C2-C20 alkanoyl, C3-C20 alkenoyl, phenyl, C1-C20 alkyl or C2-C20 alkenyl, wherein the alkanoyl, alkenoyl, alkyl and the alkenyl groups may be unsubstituted or substituted by 1 to 3 substituents chosen independently from halogen, C1-C6 alkoxy, hydroxy, aryl, aryloxy, cyano, carboxy, (C1-C6 alkoxy)carbonyl, (C3-C4 alkenyl)carbamoyl, aralkylcarbamoyl, arylcarbamoyl and -CONRcRd in which each of Rc and Rd independently is hydrogen or C1-C6 alkyl or Rc arid Rd, taken together with the nitrogen atom to which they are linked, form a morpholino or piperidino ring; or two of R4, R5 and R6 taken together form a C4-C12 polymethylene chain, which can be unsubstituted or substituted by a C1-C12 alkyl, by a C2-C12 alkenyl or by a C1-C12 alkylidene group, wherein the alkyl, alkenyl and alkylidene groups may be in turn unsubstituted or substituted by a substituent chosen from halogen, C1-C6 alkoxy, hydroxy, cyano, carboxy, (C1-C6 alkoxy)carbonyl, aryloxy and aryl; the remaining one being hydrogen or C1-C12 alkyl; and the pharmaceutically acceptable salts thereof, are disclosed.
Patent JP-3313714-B2 (JP)
IPC: A61P9/08
Filed: 1993-05-05
Granted: 2002-08-12
Abstract: PCT No. PCT/FI93/00191 Sec. 371 Date Nov. 22, 1994 Sec. 102(e) Date Nov. 22, 1994 PCT Filed May 5, 1993 PCT Pub. No. WO93/21921 PCT Pub. Date Nov. 11, 1993.A method for preventing or treating myocardial ischemia in a mammalian organism is disclosed. The compound [[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]propanedinitrile or its enantiomer or a pharmaceutically acceptable salt there is administered to a mammalian organism in need of such prevention or treatment. The compound may be administered in its racemic form or in a form which is substantially free of the (+)-enantiomer or substantially free of the (-)-enantiomer.
Patent JP-2824151-B2 (JP)
IPC: A61M5/24
Filed: 1994-03-14
Granted: 1998-11-11
Abstract: A cartridge assembly for holding a lyophilized product, forming a disposable portion of a pen injector includes a cylindrical glass cartridge adapted to receive the product, a closure cap, a cartridge case, and a plunger mechanism. The closure cap is adapted to retain an elastomeric disc seal during lyophilization and includes diametrically opposed ledges. The closure cap and seal are adapted to cover a neck portion of the ampule, the neck portion having on its end a radially extending circumferential flange. The ledges of the closure cap and the flange of the neck portion allow the closure cap to remain open during lyophilization, oxygen purge and nitrogen overlay. An oval-shaped indentation formed on the inside of the closure cap aids in snapping the closure cap about the flange without crimping to retain the closure cap underneath the flange. Reconstitution of the lyophilized drug is accomplished without foaming by use of an obliquely angled connector which causes the diluent to indirectly impinge on the drug. The injection pen and cartridge assembly cooperate such that the length of travel of the plunger rod during retraction is less than the axial length of a recess in the rod tip.
Patent JP-4436460-B2 (JP)
IPC: C07D517/06
Filed: 1998-02-26
Granted: 2010-03-24
Abstract: The invention concerns compounds of formula (I) in which R1 represents a sulphur or selenium atom, R2 represents hydrogen or alkyl, -R3-R4-R5- represents a chain of formula -CH2-CH2-CH2-, -CH(R7)-CH2-CH2-, -CH2-CH2-CH(R8)-, -CH2-CH(R9)-CH2-, -CH2-CH2-S-, -CH2-CH2-SO-, -CH2-CH2-SO2-, -CH2-CH2-Se-, -CH2-CH2-O-, -CH2-CH2-CO-, -CH2-CH2-N(R10)-, -CH2-CO-N(R10)-, -CH2-CF2-CH2-, -CH2-CF2-CH(OH)-, -CH2-CH(R13)-S-, -CH2-CH(R13)-SO-, or -CH2-CH(R13)-SO2-, R6 represents a polyfluoroalkyl, polyfluoroalcoxy or polyfluoroalkylthio radical, R7 represents alkyl, -CH2OH, -CH2-SO2-alk or -CH2-NR11R12, R8 represents alkyl, hydroxy, -CH2OH, -NR11R12, -CH2-NR11R12, -S-alk, -SO-alk, -SO2-alk, thienyl, furyl, phenyl, or phenyl substituted, R9 represents alkyl or -CH2OH, R10 represents hydrogen or alkyl, R11 represents hydrogen or alkyl, -CO-alk or -CO-CF3, R12 represents hydrogen or alkyl, or R11 and R12 form with the nitrogen atom to which they are bound a heterocyclic compound, R13 represents alkyl or -CH2OH, their salts, their methods of preparation, medicines containing them and the intermediates.
Patent PL-161855-B2 (PL)
Title: Harvesting attachment
Inventor: CZERNEK BOGUSLAW
IPC: A01D51/00
Filed: 1990-05-07
Abstract: 1. Gathering attachment, consisting of a frame, support, ejector, chain gear, screen, tighteners and beam wheels, characterized in that it is fastened detachably, so as to allow back-and-forth movement, through an intermediate fastener (14), to a dung spreader (1) in its rear part and on the frame (7) a double chain wheel (11) collecting the driving force from the spreader (1) and transferring it to the ejector (2) and gatherer (10), while the chain wheel (4) of the ejector (2) operates on the outside of the chain (6), and the gatherer (10) has a regulating beam wheel (9), whereas the ejector (2) has a directing screen (3) on its perimeter.<IMAGE>
Patent EA-004155-B2 (EA)
Title: Swath trailed reaper, device for horizontal stabilization of reel and driving device for cutting unit of the reaper
Inventor: KIM VALERIY MIKHAJLOVICH
IPC: A01D34/03
Filed: 2002-10-17
Abstract: The invention relates to agricultural machinery, in particular, to trailed swath reapers.The technical result is aimed at enhancing longitudinal stability of the reaper operated at any “heavy field conditions” and providing optimum conditions for the reaper transporting.According to the invention the trailed swath reaper comprises a trailed unit, a support frame with a self-adjusting full-circle wheel, the frame comprises left wheel and right tongues, a support and a crossbar connecting the wheel tongue to the support, the lower tying to brackets for connecting the trailed unit to the support frame, kinetically connected a platform thereto with working organs and actuating mechanism through a hydro cylinder and a system balancing springs. Two support wheels of the platform are mounted at angles attack and camber, wherein the left wheel is self-adjusting and full circle and the right wheel mounted on the turning axle is kinetically connected to the platform carrier bar, the left wheel tongue, the left wheel tongue is made of two hinge-connected parts with possible their rigid fixation, while the crossbar is rigidly connected to the front part of the wheel tongue by its one end and by its second end to the support through a flange connection. In the device of the reel horizontal stabilization a rod is adjustable over the length by a screw pair and disposed above the carrier bar. In the device of the cutting unit drive a crankshaft is arranged vertically, a rocking arm is designed as a single-shoulder lever, with two semi-axes rigidly connected atop and below thereon, the upper semi-axis is connected to the crankshaft through a connecting rod, the lower semi-axis to a head of the shear blade, both connecting rod and shear blade head are disposed at two mutually-parallel levels.
Patent ES-2338516-B2 (ES)
Title: Maquina perfeccionada para la formacion de armaduras para hormigon.
Inventor: FUERTES RODRIGUEZ MANUEL
IPC: B21F27/10
Filed: 2008-11-06
Granted: 2011-02-09
Abstract: Máquina perfeccionada para la formación de
armaduras para hormigón, constituida por una mesa de montaje (1) y
una mesa dispensadora (2) dispuestas longitudinal y adyacentemente.
La mesa de montaje (1) comprende un bastidor de apoyo ( 3 ) fijo,
con brazos (9) emergentes dotados de poleas (10), y una bandeja (4)
con movimiento de elevación y traslación, hacia delante y hacia
atrás, formada por listones (14) con rodillos transversales con
poleas (15) y medios de fijación para los estribos. La mesa
dispensadora (2) comprende un armazón (21) elevable, con un conjunto
de rodillo (24), carril de poleas (25) y pletina de soporte (26),
con movimiento hacia delante y hacia atrás, con un grupo de empuje,
solidariamente acoplado al extremo del carril de poleas (25),
formado por un rodillo listo (31) y uno estriado (32) dispuestos
oblicuamente, y accionados por un motor (33) para empujar las barras
a la mesa de montaje.
Patent ES-2390302-B2 (ES)
Title: Sistema embarcado en vehículos y método para la detección del estado del asfalto
Inventor: LOPEZ NAVARRO JUAN MANUEL
IPC: B60W40/06
Filed: 2012-07-04
Granted: 2013-02-25
Abstract: Sistema embarcado en vehículos y método para la detección del estado del asfalto. El sistema comprende:#- medios detectores de sonido (MR) configurados para registrar el ruido de rodadura generado por la interacción de una rueda (R) del vehículo con el asfalto (C),#y#- un sistema central de proceso (SP) configurado para recibir y analizar la señal procedente de los medios detectores de sonido (MR), y comprendiendo:#un módulo de extracción de características (EC) para extraer unas características espectrales (CE) de dicha señal determinadas durante un proceso previo de entrenamiento;#un módulo de vectores de soporte (DE) para almacenar unos vectores de soporte (VS) obtenidos tras un proceso previo de entrenamiento; y#un módulo clasificador (CL) para ejecutar un algoritmo de máquinas de vectores de soporte sobre las características espectrales (CE) extraídas y los vectores de soporte (VS), y obtener una estimación del estado del asfalto (EA).
Patent ES-2592352-B2 (ES)
Title: Procedimiento para la prevención y/o el control biológico de la marchitez causada por Ralstonia solanacearum, a través del uso de bacteriófagos útiles para ello y composiciones de los mismos
Inventor: GONZALEZ BIOSCA ELENA
IPC: A01N63/40
Filed: 2015-05-26
Granted: 2017-07-10
Abstract: Procedimiento para la prevención y/o el control biológico de la marchitez causada por Ralstonia solanacearum, a través del uso de bacteriófagos útiles para ello y composiciones de los mismos.#Se divulga la caracterización estructural, secuencia genómica y actividad de tres bacteriófagos líticos específicos de R. solanacearum. Se trata de podovirus, que, entre 4ºC y 30ºC, presentan una elevada estabilidad en medio acuoso en ausencia de huésped. Por su alta estabilidad, actividad lítica, elevada especificidad por R. solanacearum y la ausencia de actividad frente a la microbiota asociada a las plantas a proteger, se propone su uso para el control biológico de R. solanacearum en cursos fluviales y aguas de riego, así como un procedimiento para prevenir y/o controlar la marchitez producida por dicha bacteria en el que al menos uno de dichos bacteriófagos, o combinaciones de ellos, se aportan a las plantas y/o suelo en el agua de riego.
Patent AU-2001241850-B2 (AU)
Title: Protein scaffolds for antibody mimics and other binding proteins
Inventor: WAGNER RICHARD W
IPC: C12N15/62
Filed: 2001-02-28
Granted: 2006-09-07
Abstract: Disclosed herein are proteins that include a fibronectin type III domain having at least one randomized loop. Also disclosed herein are nucleic acids encoding such proteins and the use of such proteins in diagnostic methods and in methods for evolving novel compound-binding species and their ligands.
Patent AU-2002225185-B2 (AU)
Title: A combination of a guard bed and a catalyst bed
Inventor: WATSON MICHAEL JOHN
IPC: B01J8/04
Filed: 2002-01-22
Granted: 2005-10-27
Abstract: A combination comprising a bed of a particulate copper-containing catalyst bed, a guard bed in the form of shaped units formed from lead carbonate and/or basic lead carbonate particles having an average (by volume) particle size below 100 mum.
Patent AU-2002321596-B2 (AU)
Title: Illumination system
Inventor: ANDERSON KEITH
IPC: H05B44/00
Filed: 2002-08-30
Granted: 2007-07-12
Abstract: A light emitting diode illumination control system is disclosed for driving a current circuit for energizing one or more LED light sources. The system comprises a control system including a microprocessor arranged to control a pulse amplitude modulated (PAM) voltage controlled current circuit, and may employ a monitor for monitoring at least one ambient condition and a microprocessor operable to control the current circuit in response to the monitored condition.
Patent AU-2002356713-B2 (AU)
Title: Multicompartment device for preparing an emulsion
Inventor: WILLIAMS MARTIN ALEXANDER KEIT
IPC: A23G1/00
Filed: 2002-11-25
Granted: 2005-07-07
Abstract: A multicompartment device suitable for preparing a spreadable oil and water emulsion, said a device comprising at least two compartments, separated by at least partially removable separation means, wherein one compartment comprises at least one aqueous phase and another compartment comprises at least one oil phase. Removal of the separation means enables mixing of the ingredients of the at least two compartments to form a spreadable oil and water emulsion.
Patent AU-2003202806-B2 (AU)
Title: Dye mixture and ink containing the same
Inventor: TATEISHI KEIICHI
IPC: C09B67/22
Filed: 2003-01-17
Granted: 2008-11-06
Abstract: A novel compound having sufficiently high fastness to light, heat, humidity and active gas in the environment and a coloring composition using the compound, particularly, an ink for ink jet recording, an ink jet recording method and a method for improving the preservability of formed image, which can form an image having high fastness to light and ozone gas in the environment. A phthalocyanine dye mixture having a specific structure and an ink, an ink for ink jet recording, an ink jet recording method and a method for improving the preservability of formed image, using the phthalocyanine dye mixture.
Patent AU-2003215378-B2 (AU)
Title: Vaginal douches, vaginal douche applicators and methods of vaginal douching
Inventor: ABBOTT DOMINIC C
IPC: A61M3/02
Filed: 2003-02-20
Granted: 2008-05-15
Abstract: A method of treating abnormal biological conditions arising in and/or affecting the vagina involves supplying a flow of water to the vaginal canal while a treatment device having an external surface of stainless steel is disposed therein so as to primarily or preventatively treat an existing or potential abnormal biological condition including fungal, bacterial, viral, inflammatory and neoplastic conditions. The supply of water to the vaginal canal while the stainless steel of the treatment device is disposed therein causes a natural reaction to occur in the vaginal canal which prevents and/or normalizes abnormal biological conditions.
Patent AU-2003229945-B2 (AU)
Title: Duct with spiral groove
Inventor: JONES TREVOR FRANK
IPC: F16L9/00
Filed: 2003-04-25
Granted: 2009-03-26
Abstract: A duct (10) for transporting a two phase mixture has a length portion of circular cross-section (12) leading, via a transition zone (14) in which the duct cross-section changes from circular to lobed, to a zone in which its cross-section exhibits at least one lobe (16) extending helically around and along the duct. The duct has a cross-sectional area which is substantially constant, or which progressively increases, over the transition zone. The transition from circular to lobed cross-section is alternatively smooth and continuous, and the transition zone occupies a duct length in which the or each lobe becomes relocated by at least one position.
Patent AU-2003236500-B2 (AU)
Title: 1-aryl-4-substituted piperazine derivatives for use as CCR1 antagonists for the treatment of inflammation and immune disorders
Inventor: MCMASTER BRIAN E
IPC: C07D405/04
Filed: 2003-06-11
Granted: 2009-01-08
Abstract: Compounds are provided that act as potent antagonists of the CCR1 receptor, and which have been further confirmed in animal testing for inflammation, one of the hallmark disease states for CCR1. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.