baber/WOPTO huggingface dataset:
Patent NZ-527164-A (NZ)
Title: Noninvasive measurement of glucose through the optical properties of tissue
Inventor: RUCHTI TIMOTHY L
IPC: G01N21/35
Filed: 2002-01-25
Abstract: Methods and apparatus for noninvasive determination of blood analytes, such as glucose, through NIR spectroscopy utilize optical properties of tissue as reflected in key spectroscopic features to improve measurement accuracy and precision. Physiological conditions such as changes in water distribution among tissue compartments lead to complex alterations in the measured absorbance spectrum of skin and reflect a modification in the effective path length of light, leading to a biased noninvasive glucose measurement. Changes in the optical properties of tissue are detected by identifying key features responsive to physiological variations. Conditions not conducive to noninvasive measurement of glucose are detected. Noninvasive glucose measurements that are biased by physiological changes in tissue are compensated. In an alternate embodiment, glucose is measured indirectly based on natural physiological response of tissue to glucose concentration. A spectroscopic device capable of such measurements is provided.
Patent NZ-531132-A (NZ)
Title: Test enabled application for executing an application on a wireless device
Inventor: CHMAYTELLI MAZEN
IPC: H04B1/38
Filed: 2002-08-15
Abstract: A method for executing an application on a wireless device is disclosed. The method includes the steps of (a) receiving a permission associated with the wireless device, (b) requesting the execution of the application on the wireless device, (c) evaluating the permission associated with the wireless device using a rule stored in the wireless device, and (d) executing the application after evaluation of the permission and the rule indicate that the application is allowed to execute.
Patent NZ-537341-A (NZ)
Title: Quinuclidine amide derivatives as antimuscarinic agents to treat respiratory disorders
Inventor: PRAT QUINONES MARIA
IPC: C07D453/02
Filed: 2003-06-25
Abstract: A compound which is a quinuclidine amide derivative of formula (I) is described. R1 represents a hydrogen atom or a straight or branched lower alkyl group; R2 represents a group of formula (i) or (ii); p is 1 or 2; and the amide group is at positions 2, 3, or 4 of the azabicyclic ring. Use of the compound is described to be in the manufacture of a medicament for the treatment of a pathological condition susceptible to amelioration by antagonism of M3 muscarinic receptors. The condition includes a respiratory, urological or gastrointestinal disease.
Patent NZ-537565-A (NZ)
Title: Self-drilling anchor
Inventor: ERNST RICHARD J
IPC: F16B37/12
Filed: 2004-10-07
Abstract: A self drilling anchor (10) for use in a friable material, comprising: a thin-walled, elongate body (12) having an axis (6), an exterior thread (19, 21, 23), an axial bore (8) adapted to receive an elongated fastener, a proximal end (14), a drilling end (16) opposite the proximal end, and a strengthening member (58) disposed on the body; wherein the exterior thread and the strengthening member together provide sufficient structural support to the body to withstand a torsion force required for the drilling end to penetrate a substrate adjacent the friable material, the substrate having a hardness greater than the hardness of the friable material. (62) Divided out of 535792
Patent NZ-539298-A (NZ)
Title: Method for cardioprotection and neuroprotection by intravenous administration of halogenated volatile anesthetics
Inventor: TRILLO RAUL
IPC: A61K47/24
Filed: 2003-10-09
Abstract: Disclosed is the use of a halogenated volatile anesthetic in the manufacture of a formulation for treating a patient having a tissue that is subject to an ischemic event, wherein the formulation is adapted for parenteral administration of a sub-anesthetic amount of the formulation effective to improve the tissue's resistance to or tolerance of the ischemic event.
Patent NZ-540819-A (NZ)
Title: Navigation system with analysis and merging of multiple similar location results
Inventor: BROADBENT MATTHEW JOHN
Filed: 2005-06-16
Abstract: A navigation device containing map data identifying geographically distributed objects and their locations, each object identified by a series of separate data fields. The user inputs the desired destination data and a control means searches for matching objects amongst the map data and generates a results table. The control means then analyses the results table for duplicate entries and selectively merges these into single entries according to preset criteria, then outputs the merged results table.
Patent NZ-543340-A (NZ)
Title: Detection of leaks in heat exchangers
Inventor: WERNER THOMAS
IPC: G01M3/22
Filed: 2004-04-01
Abstract: A method for the detection of leaks in a heat exchanger having discrete flow paths for working fluid and heat exchange fluid, respectively. The method comprises introduction of a detection fluid within one of the flow paths and allowing air to flow through the other of the flow paths causing the detection fluid to pass in different directions in the one flow path, and detecting any detection fluid which has leaked from the one flow path to the other flow path.
Patent NZ-546037-A (NZ)
Title: Pyrazolo and imidazo-pyrimidine derivatives
Inventor: WICHMANN JUERGEN
IPC: C07D487/04
Filed: 2004-09-27
Abstract: The present disclosure relates to pyrazolo- and imidazo-pyrimidine derivatives, processes for their preparation, pharmaceutical compositions containing said derivatives and their use in the prevention and treatment of disease. More particularly, the present disclosure relates to a compound of formula (I) and the disease is selected from the group consisting of acute and/or chronic neurological disorders comprising psychosis, schizophrenia, Alzheimer's disease, cognitive disorders and memory deficits comprising mild cognitive impairment, age-related cognitive decline, vascular dementia, Parkinsons's disease, memory impairment associated with depression or anxiety, Down's syndrome, stroke, traumatic brain injury, and attention deficit disorder, restricted brain function caused by bypass operations or transplants, poor blood supply to the brain, spinal cord injuries, head injuries, hypoxia caused by pregnancy, cardiac arrest and hypoglycaemia, acute and chronic pain, Huntington's chorea, amyotrophic lateral sclerosis (ALS),dementia caused by AIDS, eye injuries, retinopathy, idiopathic parkinsonism or parkinsonism caused by medicaments, muscle spasms, convulsions, migraine, urinary incontinence, nicotine addiction, psychotic episodes, opiate addiction, anxiety, vomiting, dyskinesia and depression.
Patent NZ-556767-A (NZ)
Title: A process for the extraction of anthocyanins from black rice and composition thereof to treat cardiovascular disease
Inventor: ZAWISTOWSKI JERZY
IPC: A61K36/899
Filed: 2003-03-26
Abstract: Disclosed is the use of a composition comprising an extract of the outer layer of dehulled black rice, said extract comprising cyanidin-3-0-glucoside and peonidin-3-O-glucoside, in the manufacture of a medicament or nutraceutical for the treatment or prevention of hyperlipidemic conditions and/or hypercholesterolemia. This composition may be useful in enhancing and/or preserving the stability of HDL-C and the atherogenic lipioproteins such as LDL-C, VLDL-C, and IDL-C from oxidation, in preventing, reducing, eliminating or ameliorating injuries due to oxidative stress, and in preventing, reducing, eliminating or ameliorating the development of atherosclerotic lesions and inflammation associated therewith. Also disclosed is a process of extracting a composition comprising anthocyanins from black rice, wherein the extract is prepared by the following steps: (a) separating an outer layer, predominantly comprising the pericarp, tegmen, and aleurone layers, from a starchy endosperm in de-hulled black rice; (b) adding a solution of at least one organic solvent and an acid to the separated outer layer sufficient to achieve a pH of between 1 and 4. (c) filtering and removing the solvent and the acid from the separated outer layer to produce a pigment fraction; (d) separating constituents of the pigment fraction; and (e) collecting an anthocyanin composition, comprising cyanidin-3-O-glucoside and peonidin-3-O-glucoside, therefrom.
Patent NZ-587158-A (NZ)
Title: Fluid supply assembly with a disposable container placed inside an outer reuseable cup
Inventor: KOSMYNA MICHAEL J
IPC: B05B7/24
Filed: 2005-06-01
Abstract: A fluid supply assembly 45 comprises a flexible, disposable cup 55 having a side wall, an open outlet end, and a closed bottom defining an interior, a disposable lid 350, a reusable cup holder having a side wall, an open upper end, and a lower end, and a reusable outer lid 170 having an integrally connected fitting 505. The disposable lid 350 has an integrally connected fitting with an opening through it, and a sealing portion 380 at an outside thereof. The sealing portion 380 is adapted to fit into the open outlet end of the disposable cup 55, and forms a seal with the sidewall. The seal has an area, wherein the sealing portion 380 extends upward from the outside or downward from the outside. The reusable cup holder is adapted to receive the disposable cup 55 and has a connecting surface at the upper end. The fitting of the reusable outer lid 170 has an opening through it, with the fitting of the disposable lid adapted to fit into the fitting 505 of the reusable outer lid 170. The reusable lid holder has a complementary connecting surface 190 adapted to mate with the connecting surface on the reusable cup holder to seal the reusable cup holder and reusable outer lid 170 together. The reusable outer lid 170 has a projection 197 extending downward from an underside. The projection 197 is adapted to deflect the disposable lid 350 downward, forcing the sealing portion 380 outward against the sidewall thereby increasing the area of the seal.
Patent NZ-589618-A (NZ)
Title: PAEDIATRIC COMPOSITIONS COMPRISING 2-Amino-2-[2-(4-C2-20-alkyl-phenyl)ethyl]propane-1,3-diol FOR TREATING MULTIPLE SCLEROSIS
Inventor: KOVARIK JOHN
IPC: A61K31/137
Filed: 2009-06-19
Abstract: Disclosed is the use of a pharmaceutical composition comprising less than 0.5 mg of a 2-amino-2-[2-(4-C2-20 alkylphenyl)ethyl]propane-1,3-diol compound for the treatment, prevention or delay of progression of multiple sclerosis in a patient, wherein the composition is adapted for oral administration and wherein the patient is a paediatric patient such as an infant, child or adolescent. 2-amino-2-[2-(4-C2-20 alkylphenyl)ethyl]propane-1,3-diol compounds include FTY720 (fingolimod) and FTY720 phosphate.
Patent NZ-590276-A (NZ)
Title: Use of nifurtimox for treating giardiasis
Inventor: HARDER ACHIM
IPC: A61P33/02
Filed: 2009-06-20
Abstract: Disclosed herein is the use of nifurtimox for the preparation of pharmaceuticals for the treatment of diseases caused by Giardia species, particularly diseases caused by Giardia lamblia. Also discloses are compositions containing nifurtimox and an anthelmintic, particularly an anthelmintic cyclooctadepsipeptide.
Patent NZ-591114-A (NZ)
Title: Methods of making liposomes, liposome compositions made by the methods, and methods of using the same
Inventor: ZHANG YUANPENG
IPC: A61K9/127
Filed: 2011-02-11
Abstract: A method for making a liposome formulation comprising liposomes with an entrapped compound or composition that comprises the steps; (i) Solubilising 18 w/w percent of vesicle-forming lipids in 1-12 w/w percent of an aqueous solvent at room temperature; (ii) Separately solubilising an amount of the compound or composition suitable for entrapment by a liposome in 0.00-0.01 w/w/ percent of EDTA at room temperature to form a compound or composition containing solution; (iii) Filtering the solution; (iv) Injecting a stream of the lipid solution into the compound or composition containing solution while mixing; and (v) Allowing the resulting lipid and compound or composition containing solution to hydrate for at least one hour with frequent mixing.
Patent NZ-594339-A (NZ)
Title: Anti-fgfr3 antibodies and methods using same
Inventor: ASHKENAZI AVI
IPC: A61K39/395
Filed: 2010-03-24
Abstract: 594339 ANTI-FGFR3 ANTIBODIES AND METHODS USING SAME Provided is an isolated anti-FGFR3 antagonist antibody, wherein the antibody comprises six CDRs with defined sequence variants. The antibody can be used to treat various cancers and skeletal disorders.
Patent NZ-597049-A (NZ)
Title: Pharmaceutical oral telmisartan solution
Inventor: LEHNER STEFAN
IPC: A61K9/08
Filed: 2010-05-19
Abstract: 597049 Disclosed is a pharmaceutical solution comprising telmisartan wherein one or more sugar alcohols (such as xylitol, maltitol, sorbitol, mannitol, erythritol and isomaltol) are present up to a total concentration of 40 wt.% to 70 wt.%, preferably 60 wt.% to 70 wt.%, wherein the alcohol or alcohols have a maximum content of 1000 ppm of reducing sugar before they are added to the solution, and wherein the pH of the solution has a value of 10 or higher (and which is obtainable by the presence of meglumine, sodium hydroxide, potassium hydroxide or a basic amino acid such as arginine or glutamine), and wherein the pharmaceutical solution is for treating hypertension or kidney disease in people, particularly children, old people or people having difficulty swallowing; or in animals, particularly dogs or cats.
Patent NZ-598043-A (NZ)
Title: Metering infrastructure smart cards
Inventor: ACOSTA-CAZAUBON JESUS
IPC: G01D4/00
Filed: 2012-02-07
Abstract: Disclosed is an advanced metering infrastructure (AMI) (10) comprising a plurality of generic smart devices (10, 12, 14, 16, 18), each controlled by a corresponding removable smart card (22a-22f). The removable smart card (22a-22f) causes the smart device (10, 12, 14, 16, 18) to perform a function associated with the removable smart card (22a-22f). Each of the removable smart cards (22a-22f) represents a subscriber identity module (SIM) including: a computational platform capable of storing and executing program code; and a set of application programs having program code capable of being executed on the computational platform. Each of the set of application programs is implemented to control an aspect of an associated smart device (10, 12, 14, 16, 18) into which the removable smart card (22a-22f) is inserted.
Patent NZ-599527-A (NZ)
Title: Fragmented hydrogels
Inventor: GONG GLEN
IPC: A61K9/70
Filed: 2010-11-05
Abstract: 599527 Disclosed herein are fragmented polysaccharide based hydrogel compositions and methods of making and using the same are provided. The subject polysaccharide based hydrogel compositions are prepared by combining a polysaccharide component with a hydrophilic polymer and a cross-linking agent. Also provided are kits and systems for use in preparing the subject compositions. In one embodiment the method of making a fragmented hydrogel composition comprises combining in a solution components of a hydrogel composition, comprising a polysaccharide, such as chitosan, carboxymethylcellulose, or carboxymethylchitosan having a molecular weight of 160 Dalton to 80,300 Dalton and comprising at least two reactive nucleophilic groups, a synthetic hydrophilic polymer, such as a multi-armed polyethylene glycol, with amolecular weight of 200 Dalton to 100,000 Dalton and comprising at least twonucleophilic reactive groups, and a synthetic hydrophilic crosslinker, such as a multi-armed polyethylene glycol, with a molecular weight of 200 Dalton to 100,000 Dalton and comprising at least two reactive electrophilic groups; allowing the solution to cure for a sufficient period of time to form a cured hydrogel composition; and fragmenting the cured hydrogel composition to form a fragmented hydrogel composition.
Patent NZ-602151-A (NZ)
Title: Non-fat dry milk production processes for cheesemaking
Inventor: MERRILL RICHARD K
IPC: A23C9/18
Filed: 2008-10-03
Abstract: 602151 Disclosed is a method of making a powdered dairy composition, the method comprising: adding a buffer compound to a fluid milk composition to give the milk composition a pH of about 5.5 or more; adding oxidoreductase enzymes to the milk composition, wherein the oxidreductase enzyme enzymatically coverts reducing sugars in the milk composition into aldobionate products; adding a sequestrant for calcium and rennet to the milk composition to make treated milk, wherein the sequestrant for calcium binds calcium ions in the treated milk to a level that prevents substantially all aggregation of rennet hydrolyzed milk proteins in the treated milk; forming the treated milk into a milk powder.
Patent NZ-602471-A (NZ)
Title: Antagonists of activin-actriia and uses for increasing red blood cell levels
Inventor: SHERMAN MATTHEW L
IPC: A61K38/00
Filed: 2009-06-26
Abstract: Disclosed is the use of an ActRIIa polypeptide in the preparation of a medicament for the treatment of anaemia and bone loss in a patient in need thereof, wherein the ActRIIa polypeptide comprises an amino acid sequence that is at least 90% identical to the amino acid sequence of SEQ ID NO:3; wherein the sequence is as disclosed in the specification.
Patent NZ-602848-A (NZ)
Title: Methods for obtaining high viable cell density in mammalian cell culture
Inventor: DORAI HAIMANTI
IPC: C12N5/07
Filed: 2009-06-12
Abstract: 602848 Disclosed is a method of increasing viable cell density in a fed batch eukaryotic cell culture comprising the steps of: a) culturing a Chinese Hamster Ovary (CHO) cell line selected from CHO-Kl and CHO-K1SV, wherein said cell line expresses both of the heterologous apoptotic-resistant (apoptoticR) genes E1B19K and AVEN and one or more genes of interest; and b) maintaining a high glucose media feed, containing about 60mM glucose or greater, during the exponential and stationary phases of the cell culture.
Patent NZ-614199-A (NZ)
Title: Pyridinyl- and pyrazinyl -methyloxy - aryl derivatives useful as inhibitors of spleen tyrosine kinase (syk)
Inventor: ATKINSON FRANCIS LOUIS
IPC: C07D403/12
Filed: 2012-03-08
Abstract: Provided are pyridinyl- and pyrazinyl- methyloxy-aryl derivatives of the general formula (I), where the variables are as defined in the specification. Examples of the compounds include 7-(2-(methyloxy)-6-{ [(4-methyl-2-pyridinyl)methyl]oxy} phenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine and 7-(5-fluoro-2-{ [(4-methyl-2-pyridinyl)methyl]oxylphenyl)-1,2,3,4-tetrahydroisoguinoline. The compounds are inhibitors of spleen tyrosine kinase (Syk). The compounds may be useful in the treatment of autoimmune and/or allergic disorders, particularly dermatological disorders, such as urticaria.
Patent NZ-616573-A (NZ)
Title: Pap system blower
Inventor: MEBASSER SAMUEL AZIZ
IPC: A61M16/06
Filed: 2012-04-18
Abstract: A blower (100), comprising: a housing (120) including an inlet (123) and an outlet (125); a bearing-housing structure (130) provided to the housing and adapted to rotatably support a rotor (170); a motor (140) provided to the bearing-housing structure, the motor including at least a stator assembly (145) adapted to drive the rotor; and an impeller (180) provided to the rotor. The bearing-housing structure includes a bearing shaft (136) having an exterior surface (136(3)) and an interior bearing surface (136(1)). The stator assembly is provided along the exterior surface of the bearing shaft and the rotor is rotatably supported by the interior bearing surface of the bearing shaft.
Patent NZ-625343-A (NZ)
Title: Coating composition for a food or beverage can
Inventor: LOCK KAM
IPC: C09D7/63
Filed: 2012-12-03
Abstract: Disclosed herein is a two component coating composition comprising: a first component comprising an acrylic latex material; and a second component comprising a functional silane material. Also disclosed is the use of the composition for coating food and beverage cans and for repairing a score line on a food or beverage can by applying the composition to the score line.
Patent NZ-627262-A (NZ)
Title: Pipe fitting assembly
Inventor: PICTON DAVID JOHN
IPC: F16L47/06
Filed: 2013-07-16
Abstract: А pipe fitting assembly (11) is disclosed. The pipe fitting has а body with a male pipe engagement section (17) which includes а plurality of engagement ridges (21) and а swage collar (15) secured at one end to the body. The swage collar (15) can be crimped or clamped over the male pipe engagement section (17) to hold а pipe (not shown) securely to the pipe fitting. Each male section (17) includes at least one feature, such as a barb (23), which is configured to allow relatively free movement of а pipe onto the male section (17) and to resist movement of а pipe back off the male section. In use, correct engagement of the pipe or hose with the fitting can be detected by the amount of resistance to pulling back on the pipe.
Patent NZ-711976-A (NZ)
Title: Processes and intermediates for making a jak inhibitor
Inventor: LIU PINGLI
IPC: C07F5/02
Filed: 2014-03-05
Abstract: This invention relates to processes of preparing a compound of Formula I, or a salt thereof, comprising reacting a compound of Formula IIIa with a compound of Formula IVa, under Suzuki coupling conditions to form a compound of Formula IIa; deprotecting the compound of Formula IIa by reacting with hydrochloric acid to form 2-(3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)azetidin-3-yl)acetonitrile dihydrochloride salt; and reacting same with a compound of Formula VI in the presence of a reducing agent to form a compound of Formula I, or a salt thereof, useful in the treatment of diseases related to the activity of Janus kinases (JAK) including inflammatory disorders, autoimmune disorders, cancer, and other diseases.
Patent NZ-717499-A (NZ)
Title: Production method for concentrated product using membrane-concentration method and freeze-concentration method
Inventor: KAMIYA TETSU
IPC: B01D61/16
Filed: 2014-08-29
Abstract: Provided is a concentrated product production method using a membrane-concentration method and a freeze-concentration method that efficiently reduce (practically applicable) processing time (concentration time) as required in large-scale (commercial-scale) production. The concentrated product production method using a membrane-concentration method and a freeze-concentration method comprises: a membrane-concentration step in which a fluid to be treated is cooled, the solid-component concentration thereof is membrane-concentrated by at least 1.5 times, and a membrane-concentrated fluid to be treated is prepared; an ice crystal generation step in which the membrane-concentrated fluid to be treated is cooled, ice crystals of the membrane-concentrated fluid to be treated are generated in the membrane-concentrated fluid to be treated, and a mixed fluid is obtained, of ice crystals and concentrated fluid to be treated being membrane-concentrated fluid to be treated further concentrated as a result of the ice crystals being generated; and an ice crystal separation step in which the mixed fluid is separated into concentrated fluid to be treated and ice crystals, and the concentrated fluid to be treated is retrieved.
Patent NZ-718607-A (NZ)
Title: Synthetic route to 2’-deoxy-2’,2’-difluorotetrahydrouridines
Inventor: CHOI HYEONG-WOOK
IPC: C07H19/06
Filed: 2014-10-29
Abstract: The present invention relates to a method of producing compound 1, or a salt thereof; comprising precipitating or crystallizing compound 1 from a solution of compound 2, in the presence of a catalyst, wherein the catalyst is 1,8-diazabicyclo(5.4.0)undec-7-ene (DBU), acetic acid, trifluoroacetic acid, diisopropylethylamine, or ammonium hydroxide.
Patent NZ-721802-A (NZ)
Title: S1p3 antagonists
Inventor: CARAMELLI CHIARA
IPC: C07D213/75
Filed: 2014-11-28
Abstract: The present invention relates to antagonists of the S1P3 receptor formula (A) as herein described and pharmaceutical compositions thereof. The compounds of formula (A) are useful in the preparation of a medicament, in particular for the treatment of Alzheimer’s disease.