baber/WOPTO huggingface dataset:
Patent AU-2019218978-A1 (AU)
Title: Toll-like receptor ligands
Inventor: BAZIN-LEE HELENE
IPC: A61K39/02
Filed: 2019-02-12
Abstract: Toll-like receptor (TLR) ligands having an allose-based core are stable in aqueous formulation and are useful in treating, preventing, or reducing susceptibility to diseases or conditions mediated by TLRs, such as cancer, infectious disease, allergy, autoimmune disease, sepsis, and ischemia reperfusion.
Patent AU-2019241727-A1 (AU)
Title: Spigot ferrule-type fishing rod
Inventor: TSUKAMOTO YASUHIRO
IPC: A01K87/00
Filed: 2019-03-29
Abstract: This fishing rod is provided with a hollow small-diameter rod body which extends in the central axis direction, a hollow large-diameter rod body which extends in the central axis direction, and a spigot ferrule core which links the small-diameter rod body and the large-diameter rod body by being inserted into the small-diameter rod body from the back end and inserted into the large-diameter rod body from the front end. In the fishing rod, on the inner peripheral surface of the small-diameter rod body, a first inclined surface inclined at an angle of 0.1° to 10.0° from the central axis direction is formed which extends from the back end of said inner peripheral surface.
Patent AU-2019243670-A1 (AU)
Title: Humidification chamber and apparatus and systems including or configured to include said chamber
Inventor: SPENCE CALLUM JAMES THOMAS
IPC: A61M16/16
Filed: 2019-03-26
Abstract: In one embodiment, there is provided a humidification chamber for use in a medical humidification system. The humidification chamber may comprise: a base and a top linked by a side wall to define the chamber, the chamber being configured to contain a volume of water; a gases inlet configured to receive a gases flow from a gases source; and a gases outlet, wherein the gases inlet is orientated relative to the side wall to introduce the gases flow to the humidification chamber at a direction substantially tangential to the side wall of the humidification chamber.
Patent AU-2019246764-A1 (AU)
Title: Methods of handling avocados and system
Inventor: MIR NAZIR
IPC: B65D81/28
Filed: 2019-10-08
Abstract: This invention is based on unexpected synergistic effect of a cyclopropene compound and a modified atmosphere package to extend shelf life and/or storage for avocados. Provided is a method of storing avocados comprising the step of exposing avocados to an atmosphere that contains a cyclopropene compound, wherein either (a) the avocados are in a modified-atmosphere package during exposure to the cyclopropene compound, or (b) the avocados are placed into a modified-atmosphere package after exposure to the cyclopropene compound, and the avocados remain in the modified atmosphere package for at least two hours. In some embodiments, the modified-atmosphere package is constructed so that the transmission rate of oxygen for the entire package is from 200 to 40,000 cubic centimeters per day per kilogram of avocados.
Patent AU-2019257249-A1 (AU)
Title: KIR3DL3 as an HHLA2 receptor, anti-HHLA2 antibodies, and uses thereof
Inventor: FREEMAN GORDON J
IPC: A61K38/00
Filed: 2019-04-05
Abstract: The present invention is based, in part, on the discovery of monoclonal antibodies, and antigen-binding fragments thereof, that specifically bind to HHLA2, as well as immunoglobulins, polypeptides, nucleic acids thereof, and methods of using such antibodies for diagnostic, prognostic, and therapeutic purposes.
Patent AU-2019257680-A1 (AU)
Title: Sustained release formulation for local delivery of CDK9 inhibitors
Inventor: HAUDENSCHILD DOMINIK R
IPC: A61K48/00
Filed: 2019-04-23
Abstract: The present disclosure describes a novel sustained-release formulation for the local delivery of CDK9 inhibitors.
Patent AU-2019266231-A1 (AU)
Title: Selection of patients for combination therapy
Inventor: ORDENTLICH PETER
IPC: G01N33/574
Filed: 2019-05-07
Abstract: Described herein are methods for selecting cancer patients for treatment with a combination therapy comprising an HDAC inhibitor and a second therapeutic agent. In particular, methods are provided for the examination of a non-cancer cell type which are CD14-positive, HLA-DR-high and/or CD16-negative, as a therapeutic indicator in the setting of HDAC inhibitor combination therapies.
Patent AU-2019271267-A1 (AU)
Title: Bi-directional, water separating flow nozzle
Inventor: SCHAUPP JOHN
IPC: B05B1/26
Filed: 2019-05-16
Abstract: The present disclosure is directed to a fluid separating flow nozzle which has a diffuser housing configured to be secured to a source of compressed fluid, and a diffuser element secured within a portion of the diffuser housing. The diffuser element may have at least one flow path opening forming a flow path through the flow nozzle, a nose portion and a moisture capturing area adjacent the nose portion for capturing moisture particles when a first airflow is directed through the flow nozzle in a first direction. A flow turning element may be incorporated which has a plurality of flow turning structures, and which is in communication with the flow path opening, and which imparts a turning motion to the first airflow and also to a second airflow flowing in a direction opposite to the first airflow. The turning motion helps to displace and eject moisture particles from the nose portion and from the moisture capturing area while the second airflow is occurring.
Patent AU-2019280450-A1 (AU)
Title: A semi-wet milling strategy to fabricate ultra-small nano-clay
Inventor: ZHANG JUN
IPC: C01B33/40
Filed: 2019-06-05
Abstract: A method for producing nano-clays comprising forming a mixture of a clay and water, wherein water is present in an amount of from 2 to 10% by weight of the total weight of clay and water, and milling the mixture of clay and water in the presence of a grinding media to form the nano-clay.
Patent AU-2019306194-A1 (AU)
Title: Gene therapy of hemophilia A using viral vectors encoding recombinant FVIII variants with increased expression
Inventor: ROTTENSTEINER HANSPETER
IPC: C07K14/755
Filed: 2019-07-15
Abstract: The present disclosure provides, among other aspects, codon-altered polynucleotides encoding Factor VIII variants for expression in mammalian cells. In some embodiments, the disclosure also provides mammalian gene therapy vectors and methods for treating hemophilia A. In some embodiments, the present disclosure provides methods for dosing a hemophilia A patient with a polynucleotide, e.g., a codon-altered polynucleotide, encoding a Factor VIII polypeptide.
Patent AU-2019326931-A1 (AU)
Title: Method for controlling an exchange of energy between energy sub-systems in adjusted harmonised conditions; control centre; energy system; computer program; and storage medium
Inventor: AMTHOR ARVID
IPC: H02J3/06
Filed: 2019-08-19
Abstract: The invention relates to a method for controlling an exchange of energy in an energy system (1) having multiple energy sub-0systems (3), each connected for the exchange of energy between energy exchange with one another. In order to provide an improved method for controlling the exchange of energy, the following steps are provided: receiving respective input data (6) from the energy sub-systems (3) via a control centre (2), wherein the input data (6) comprises respective payment compensation conditions of the corresponding energy sub-system (3) for receiving and/or for providing energy; determining optimum conditions (7) based on the input data (6) of all energy sub-systems (3) of the energy system (1) via the control centre (2); and controlling the exchange of energy between the energy sub-systems (3) based on the optimum conditions (7).
Patent AU-2019347751-A1 (AU)
Title: Masked cytokine polypeptides
Inventor: KAROW MARGARET
IPC: C07K14/52
Filed: 2019-09-27
Abstract: Provided herein are cytokines or functional fragments thereof that, in some embodiments, are engineered to be masked by a masking moiety at one or more receptor binding site(s) of the cytokine or functional fragment thereof. In some embodiments, the cytokines are engineered to be activatable by a protease at a target site, such as in a tumor microenvironment, by including a proteolytically cleavable linker. In some embodiments, the proteolytically cleavable linker links the cytokine to the masking moiety, links the cytokine to a half-life extension domain, and/or links the masking moiety to a half-life extension domain. The masking moiety blocks, occludes, inhibits (e.g., decreases) or otherwise prevents (e.g., masks) the activity or binding of the cytokine to its cognate receptor or protein. Upon proteolytic cleavage of the cleavable linker at the target site, the cytokine becomes activated, which renders it capable of binding to its cognate receptor or protein with increased affinity.
Patent AU-2019350695-A1 (AU)
Title: Paint sprayer distributed control and output volume monitoring architectures
Inventor: MANSHEIM MICHAEL J
IPC: B05B12/08
Filed: 2019-09-23
Abstract: A sprayer (1) for spraying fluid includes a pump (9), a motor (4) that drives the pump (9), a drive cycle indicator (27A-C), a wireless module (23) configured to send and receive information, and control circuitry (21). The drive cycle indicator (27A-C) outputs an indication of cycle status of the pump (9). The control circuitry (21) is configured to receive the plurality of cycle status indications of the pump (9), determine a plurality of output values representing paint spray fluid output volume over a plurality of time windows based on the plurality of cycle status indications of the pump (9), store the plurality of output values in memory (22), and cause the wireless module (23) to transmit one or more of the stored plurality of output values externally from the sprayer.
Patent AU-2019403406-A1 (AU)
Title: Modified rhodamine dye and use thereof in biological assays
Inventor: EVANS BRIAN
IPC: G01N33/58
Filed: 2019-12-20
Abstract: The present invention is directed to f luorescent rhodamine dyes having spectral properties suited to the creation of multiplex assay systems for use in molecular biology, cell biology and molecular genetics. The rhodamine dyes have the following structure:
Patent AU-2019408014-A1 (AU)
Title: Marine surveying using a source vessel
Inventor: STRAND CHRISTIAN
IPC: G01V1/38
Filed: 2019-12-19
Abstract: An actuation location for actuation of a first source coupled to a first marine survey vessel relative to a position of a second marine survey vessel towing a receiver to enhance illumination of a subsurface location can be determined (1173) based on a survey route of the second marine survey vessel and a priori data of the subsurface location. The first marine survey vessel can be navigated (1174) along a survey route of the first marine survey vessel to the actuation location during a marine survey by changing at least a cross-line position or an in-line position of the first marine survey vessel relative to the survey route of the second marine survey vessel.
Patent AU-2019414427-A1 (AU)
Title: Silencing TGF-beta 1 and Cox2 using siRNAs delivered in combination with immune checkpoint inhibitors to treat cancer
Inventor: EVANS DAVID M
IPC: A61K45/06
Filed: 2019-12-24
Abstract: The present invention provides certain pharmaceutical molecules and compositions and methods of using them to treat cancer. The molecules are small interfering RNA (siRNA) molecules that inhibit TGF-beta 1 and Cox2 in humans and other mammals, which are used alone or in combination with immune checkpoint inhibitors, to treat cancer.
Patent AU-2019436353-A1 (AU)
Title: Game system having function of determining whether to trigger stereo respin mechanism
Inventor: HSU SHUN-TSUNG
IPC: G07F17/34
Filed: 2019-03-18
Abstract: The present invention relates to that a control unit is used for determining whether a game result of a slot game satisfies a specified condition, wherein the specified condition is a plurality of game symbols in the game result, a reward condition may be satisfied when any of the game symbols is replaced, and the game symbol that is replaced is defined to be located at a replacement position; when the control unit determines that the game result satisfies the specified condition, the control unit starts a stereo respin component to generate an alternate game symbol, wherein the alternate game symbol is used for replacing the game symbol at the replacement position to update the game result, furthermore, the control unit re-determines whether the updated game result satisfies the reward condition, and after the reward condition is satisfied, a reward program is performed by means of a reward unit. On this basis, in the present invention, when a player is almost ready to enter the reward program by means of the game result, stimulation feeling as that given by squinting cards is given for the player by means of the stereo respin component, and wining can be expected again so as to enhance interests of the player in playing.
Patent AU-2019452936-A1 (AU)
Title: Bispecific antibody, preparation method therefor and application thereof
Inventor: ZHANG WENJUN
IPC: C12N15/13
Filed: 2019-12-17
Abstract: Provided are a bispecific antibody and a preparation method therefor. The antibody comprises structural domains capable of binding to CD20 and CD3, and a heterodimer Fc region. The structural domains capable of binding to CD20 and CD3 are each independently selected from a Fab region, a ScFv region, or an sDab region. The bispecific antibody targets CD20 and CD3, and mediates T cell-specific killing of tumor cells.
Patent WO-2020232509-A1 (WO)
Inventor: ECKERT DANNY J
IPC: A61B5/08
Filed: 2020-05-22
Abstract: A method of predicting the likelihood of responding to one or more obstructive sleep apnea (OSA) treatments for obstructive sleep apnea (OSA) of a candidate subject, the method including the steps of: (a) measuring a first series of polysomnography and anthropometric parameters for at least a collection of OSA sufferers; (b) correlating the parameters with at least one of the corresponding upper-airway collapsibility (Pcrit), arousal threshold, loop gain and pharyngeal muscle responsiveness measurement of each subject; (c) determining a corresponding description structure describing the correlation of step (d); and (d) utilising the corresponding description structure, in conjunction with a series of polysomnography and anthropometric parameters measured for the candidate subject to predict the likelihood of responding to one or more obstructive sleep apnea (OSA) treatments to thereby provide a clinical decision diagnostic tool for obstructive sleep apnea.
Patent WO-2021035293-A1 (WO)
Title: Procédés et appareil de pompage amélioré de détecteur d'ions
Inventor: HUNTER KEVIN
IPC: H01J49/00
Filed: 2020-08-24
Abstract: La présente invention concerne de manière générale des procédés pour le fonctionnement d'un équipement analytique scientifique tel que des spectromètres de masse dans le but d'améliorer les performances et/ou la durée de vie. Un tel procédé peut comprendre les étapes consistant à : fournir un flux ionique comprenant des ions ayant une plage de masses, séparer les ions du flux ionique sur la base de la masse, et commander la synchronisation et/ou l'ordre d'impact des ions séparés sur une surface d'émission d'électrons du détecteur d'ions de façon à modifier un ou plusieurs paramètres du détecteur d'ions.
Patent WO-2021102517-A1 (WO)
Title: Agencement et procédé de gestion thermique à changement de phase fluide
Inventor: JAMES MALCOLM BARRY
IPC: B29C33/04
Filed: 2020-11-27
Abstract: Procédé et appareil de refroidissement de gestion thermique à changement de phase fluide pour éliminer la chaleur d'une source de chaleur. Le procédé consiste : à remplir une chambre de refroidissement avec un volume V1 d'un appareil de refroidissement de gestion thermique à changement de phase fluide avec un fluide dans sa phase liquide ; à augmenter le volume de la chambre de refroidissement à un volume V2 pour vaporiser une partie du fluide de sa phase liquide à sa phase vapeur de sorte qu'il n'y ait sensiblement que le fluide dans sa phase liquide et le fluide dans sa phase vapeur à l'intérieur du volume V2 ; à permettre un temps de maintien qui permet à au moins une partie du fluide dans sa phase liquide qui est en contact avec une surface chauffée de la chambre de refroidissement d'être vaporisée ; et à répéter les étapes dans lesquelles la synchronisation des étapes et du temps de maintien entre les étapes est sélectionnée pour réguler l'accumulation de chaleur dans des limites sélectionnées.
Patent AU-2020200064-A1 (AU)
Title: Optimizing loading of a payload carrier of a machine
Inventor: HA CHRISTOPHER
IPC: E02F3/64
Filed: 2020-01-03
Abstract: OPTIMIZING LOADING OF A PAYLOAD CARRIER OF A MACHINE 
A method for loading a payload carrier of a machine includes receiving, from a camera on the 
machine, a two-dimensional image of an interior of the payload carrier as material is loaded into 
the payload carrier. The method further includes filtering the image to identify a contour of the 
loaded material and determining an area of the contour. The method further includes controlling a 
display device indicate the determined area.
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Patent AU-2020200682-A1 (AU)
Title: Systems and methods of secure provenance for distributed transaction databases
Inventor: ZINDER ALEX
IPC: G06F17/00
Filed: 2020-01-30
Abstract: An electronic resource tracking and storage computer system is provided that communicates with a distributed blockchain computing system that includes multiple computing nodes. The system includes a storage system, a transceiver, and a processing system. The storage system includes an resource repository and transaction repository that stores submitted blockchain transactions. A new resource issuance request is received, and a new resource is added to the resource repository in response. A new blockchain transaction is generated and published to the blockchain. In correspondence with publishing to the blockchain, the transaction storage is updated with information that makes up the blockchain transaction and some information that was not included as part of the blockchain transaction. The transaction storage is updated when the blockchain is determined to have validated the previously submitted blockchain transaction. too no 0 wC bD M co UD ti
Patent AU-2020203691-A1 (AU)
Title: Multifunctional training apparatus
Inventor: STROFIELD THOMAS WILLIAM
IPC: A63B17/00
Filed: 2020-06-04
Abstract: The present invention relates to a multifunctional training apparatus comprising a 
base, a front wall, a pair of side walls and a rear wall connected to the base, and 
5 a top comprising a seat portion and a bench portion, wherein the bench portion 
is pivotable relative to the seat portion, and wherein the bench portion is adapted 
to be maintained in a plurality of positions. The present invention alleviates the 
problem of storage and requiring a plurality of personal exercise equipment.
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Patent AU-2020214294-A1 (AU)
Title: Urinary pumping device
Inventor: OBRIST DOMINIK
IPC: A61B5/20
Filed: 2020-01-29
Abstract: An urinary pumping device (17) for generating a fluid flow through an urethra of a patient comprises an activation arrangement (117) configured to induce intermittent compression and release of the urethra, and a mounting structure (117) to mount and unmount the activation arrangement (117) to a body of the patient. The mounting structure (117) is configured to position the activation arrangement (117) on the body of the patient such that the urethra of the patient can be intermittently compressed and released by means of the activation arrangement (117).
Patent AU-2020222326-A1 (AU)
Title: Anti-BAG2 antibody and methods of treating cancer
Inventor: KIM SEONG JIN
IPC: A61P35/00
Filed: 2020-02-12
Abstract: The present application discloses an antibody or antigen-binding fragment thereof that binds specifically to a BAG2 polypeptide or fragment thereof, and a method of treating cancer thereof.
Patent AU-2020229690-A1 (AU)
Title: Catheter placing instrument
Inventor: KHALAJ STEVE S
IPC: A61M25/01
Filed: 2020-02-11
Abstract: A catheter placing instrument is provided. The catheter placing instrument includes an elongated body that extends in a longitudinal direction from a proximal end to a distal end. The elongated body has a top surface configured to receive a catheter extending from the proximal end to the distal end. The elongated body includes a catheter insertion section and a grip section. The catheter insertion section includes a catheter locking clamp located at the distal end of the elongated body, and the grip section includes a catheter guide. The catheter placing instrument can be used to place or implant any tubular medical device within a patient's body. A method of placing a tubular medical device at a deep location within a patient's body is also provided.
Patent AU-2020233223-A1 (AU)
Title: In vitro method for assessing the risk of prostate side effect after treatment by ionizing radiation
Inventor: AZRIA DAVID
IPC: G01N33/50
Filed: 2020-03-05
Abstract: The present invention relates to an
Patent AU-2020246764-A1 (AU)
Title: Terminal energy saving method based on bandwidth part
Inventor: YANG TUO
IPC: H04W72/04
Filed: 2020-03-27
Abstract: Provided are a terminal energy saving method and device based on a bandwidth part. The present disclosure realizes a BWP having at least two configuration states or configuration indexes, and configures one of the at least two configuration states or configuration indexes for a terminal by means of a first information domain.
Patent AU-2020257392-A1 (AU)
Title: Gene therapies for Stargardt disease (ABCA4)
Inventor: KHANNA HEMANT
IPC: C12N15/86
Filed: 2020-04-16
Abstract: Aspects of the disclosure relate to compositions and methods useful for delivering minigenes to a subject. Accordingly, the disclosure is based, in part, on isolated nucleic acids and gene therapy vectors, such as viral (
Patent AU-2020281116-A1 (AU)
Title: Motor and Fuel-Powered Hybrid System for a Rocket Thruster
Inventor: CHEN YEN-SEN
IPC: B64G1/40
Filed: 2020-12-03
Abstract: OF THE DISCLOSURE 
A motor and fuel-powered hybrid system of a rocket thruster is disclosed, 
which mainly provides power through an electric motor and a fluid fuel injector. In 
particular, at the beginning stage of the rocket lift-off, the motor drives the 
compressor to provide power to send the rocket into air. When the speed and height 
of the rocket gradually increase, the fuel is ignited to give power to keep propelling 
the rocket, thereby reducing the fluid fuel that needs to be carried on the rocket, 
increasing the rocket's loading space and enhancing the carrying capacity.  
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Patent AU-2020308851-A1 (AU)
Title: Nano-inks of carbon nanomaterials for printing and coating
Inventor: DAS SUPREM R
IPC: C09D11/52
Filed: 2020-06-25
Abstract: Electrically conductive ink compositions are provided that comprise at carbon nanomaterials of one-dimensional, two-dimensional, and quasi-three-dimensional nanostructures and/or their combinations, and/or doping with elements such as nitrogen, boron, sulfur, in certain ratios. The carbon nanomaterials are selected from the group consisting of graphene and graphene oxide particles, carbon nanotubes, and graphene aerosol gels.
Patent AU-2020369151-A1 (AU)
Title: Method for screening IVF embryos
Inventor: MURPHY NICHOLAS MARK
IPC: G16B20/20
Filed: 2020-10-21
Abstract: The present invention relates to methods of screening in vitro fertilization (IVF) embryos for pathogenic genetic variations, such as single nucleotide polymorphisms. In particular, the present invention relates to methods of screening IVF embryos using whole genome sequencing (WGS) data. The present invention also relates to methods of screening in vitro fertilization (IVF) embryos for phenotypic traits.