baber/WOPTO huggingface dataset:
Patent CA-2356532-A1 (CA)
Title: Noninvasive vascular therapy
Inventor: CHEN JAMES
IPC: A61K41/00
Filed: 2000-01-14
Abstract: The present invention is drawn to methods and compounds for transcutaneous photodynamic therapy ("PDT") of a target tissue or compositions in a mammalian subject, which includes administering to the subject a therapeutically effective amount of a photosensitizing agent or a photosensitizing agent delivery system or a prodrug, where the photosensitizing agent or photosensitizing agent delivery system or prodrug selectively binds to the target tissue; and irradiating at least a portion of the subject with light at a wavelength absorbed by the photosensitizing agent or if prodrug, by a prodrug product thereof, where the light is provided by a light source, and where the irradiation is at low fluence rate that results in the activation of the photosensitizing agent or prodrug product. These methods of transcutaneous PDT are useful in the treatment of specifically selected target tissues, such as: vascular endothelial tissue; abnormal vascular wall of tumors; tumors of the head and neck; tumors of the gastrointestinal tract; tumors of the liver;  tumors of the esophopharyngeal; tumors of the lung; lymphoid tissue; lesions in the vascular system; bone marrow and tissue related to autoimmune disease.
Patent CA-2357196-A1 (CA)
Title: Microcomposant du type micro-inductance ou microtransformateur
Inventor: FEDELI JEAN-MARC
IPC: H01F10/12
Filed: 2001-09-11
Abstract: Microcomposant inductif (1), tel que micro-inductance ou microtransformateur, comportant un bobinage métallique (2) ayant la forme d' un solénoïde, et un noyau magnétique (4) incluant un ruban en un matériau ferromagnétique, positionné au centre du solénoïde (2), caractérisé en ce qu e le noyau comporte au moins un ruban supplémentaire en un matériau ferromagnétique (13), séparé de l'autre ruban (12) par une couche de séparation (14) en un matériau amagnétique dont l'épaisseur est telle que les rubans (12,13) situés de part et d'autre de la couche de séparation (14) sont couplés antiferromagnétiquement.
Patent CA-2357209-A1 (CA)
Title: Cannula assembly
Inventor: BOOTH CHARLES S
IPC: A61M5/165
Filed: 2001-09-07
Abstract: Cannulas, as well as cannula assemblies including gas filters, are disclosed.
Patent CA-2360451-A1 (CA)
Inventor: MOGYOROSI TAMAS
IPC: A61K31/44
Filed: 2000-02-24
Abstract: The invention relates to N-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboximidoyl chloride, its stereoisomers and the acid addition salts thereof, pharmaceutical compositions containing the same, the use of these compounds in the treatment of pathological insulin resistance, and for the treatment of pathological conditions associated therewith, for the treatment of pathological insulin resistance, and the treatment of pathological conditions associated therewith, by simultaneous treatment and prevention of diabetes-induced chronic complications, especially retinopathy, neuropathy and nephropathy and/or with simultaneous increasing pathologically decreased peripheral neuroregeneration caused by diabetes and methods of treatment.
Patent CA-2360908-A1 (CA)
Title: Complexes bis-terpyridine-platinum (ii)
Inventor: LOWE GORDON
IPC: C07D213/22
Filed: 2000-01-18
Abstract: L'invention porte sur des complexes 2,2':6',2"-terpyridine Pt(II) de la structure (I) qui possèdent des propriétés leur conférant une grande utilité comme agents antitumoraux.
Patent CA-2364190-A1 (CA)
Inventor: VANDENBROUCKE ERIC
IPC: G01V1/16
Filed: 2001-12-11
Abstract: - Méthode et dispositif d'exploration sismique d'une zone souterraine immergée, utilisant des récepteurs sismiques couplés avec le fond de la masse d'eau.  - On utilise des unités d'acquisition comprenant une flèche où sont localisé s des récepteurs sismiques, un compartiment de mesure pour l'acquisition et la mémorisation des données reçues par les récepteurs et des moyens de flottaison amovibles et sélectifs. Les unités d'acquisition sont mouillées et, par l'effet de la gravité, elles viennent se ficher dans le fond et coupler les récepteurs avec les formation s sous- jacentes. On détecte dans un premier temps leurs positions respectives, on réalise des opérations d'acquisition sismique en utilisant une source immergée, de maniè re à collecter des données sismiques sur la formation et ensuite on actionne les moyens de flottaison pour faire remonter tout ou partie des unités d' acquisition ou bien on fait descendre jusqu' au voisinage des différentes unités un moyen de collecte de s données (véhicule ou unité passive de collecte).  - Applications à la prospection ou la surveillance sismique d'un gisement d'hydrocarbures par exemple.
Patent CA-2366880-A1 (CA)
Title: Compositions of polyacids and polyethers and methods for their use in reducing adhesions
Inventor: BLACKMORE JOHN M
IPC: A61K47/36
Filed: 2000-03-23
Abstract: The present invention relates to improved methods for making and using bioadhesive, bioresorbable, anti-adhesion compositions made of intermacromolecular complexes of carboxyl-containing polysaccharides, polyethers, polyacids, polyalkylene oxides, multivalent cations and/or polycations. The polymers are associated with each other, and are then either dried into membranes or sponges, or are used as fluids or microspheres.  Bioresorbable, bioadhesive, anti-adhesion compositions are useful in surgery to prevent the formation and reformation of post-surgical adhesions. The compositions are designed to breakdown in-vivo, and thus be removed from the body. Membranes are inserted during surgery either dry or optionally after conditioning in aqueous solutions. The anti-adhesion, bioadhesive, bioresorptive, antithrombogenic and physical properties of such membranes and gels can be varied as needed by carefully adjusting the pH and/or cation content of the polymer casting solutions, polyacid composition, the polyalkylene oxide composition, or by conditioning the membranes prior to surgical use. Multi-layered membranes can be made and used to provide further control over the physical and biological properties of antiadhesion membranes.  Membranes and gels can be used concurrently. Antiadhesion compositions may also be used to lubricate tissues and/or medical instruments, and/or deliver drugs to the surgical site and release them locally.
Patent CA-2369591-A1 (CA)
Title: Disodium salts, monohydrate, and ethanol solvates
Inventor: CHAUDHARY KIRAN
IPC: C07C231/00
Filed: 2000-04-05
Abstract: The inventors have discovered that the disodium salt of certain delivery agents has surprisingly greater efficacy for delivering active agents than t he corresponding monosodium salt. Furthermore, the inventors have discovered th at the disodium salts of these delivery agents form solvates with ethanol and hydrates with water. The delivery agents have formula (I) wherein R1, R2, R3 , and R4 are indepedently hydrogen, halogen, C1-C4 alkyl, or C1-C4 alkoxy; and  R5 is a substituted or unsubstituted C2-C16 alkylene, substituted or unsubstituted C2-C16 alkenylene, substituted or unsubstituted C1-C12 alkyl(arylene), or substituted or unsubstituted aryl(C1-C12 alkylene). The hydrates and solvates of present invention also have surprisingly greater efficacy for delivering active agents, such as heparin and calcitonin, than their corresponding monosodium salts and free acids. The present invention provides an alcohol solvate, such as ethanol solvate, of a disodium salt of a delivery agent of formula (I) above. Preferred delivery agents include, but are not limited to, N-(5-chlorosalicyloyl)-8-aminocaprylic acid (5-CNAC),N-( 10- [2-hydroxybenzoyl]amino)decanoic acid (SNAD), and sodium N-(8-[2- hydroxybenzoyl]amino)caprylate (SNAC). The invention also provides methods o f preparing the disodium salt, ethanol solvate, and hydrate and compositions containing the disodium salt, ethanol solvate, and/or hydrate.
Patent CA-2372122-A1 (CA)
Inventor: HUFFER SCOTT W
IPC: B65D33/20
Filed: 2002-02-15
Abstract: A flexible container for dispensing liquids is disclosed. The flexible container includes a spout which is integrally formed with a reservoir body of the container. The integral spout includes a cohesive material disposed across the spout opening for providing easy access to the reservoir and which then may be resealed.
Patent CA-2374233-A1 (CA)
Inventor: BECK JEFFREY S
IPC: C10G69/04
Filed: 2000-05-18
Abstract: This is a process for upgrading a petroleum naphtha fraction. The naphtha is  subjected to reforming and the reformate is cascaded to a benzene and toluen e synthesis zone over a benzene and toluene synthesis catalyst comprising a molecular sieve of low acid activity. The preferred molecular sieve is steam ed ZSM-5. The benzene and toluene synthesis zone is operated under conditions compatible with the conditions of the reformer such as temperatures of above  about 800 ~F (427 ~C). In one aspect of the invention, the benzene and tolue ne synthesis catalyst includes a metal hydrogenation component from group VII(B ), specifically rhenium. In one mode of operation, the benzene and toluene synthesis catalyst replaces at least a portion of the catalyst in the reformer. The process produces a product containing an increased proportion of benzene, toluene, and/or xylenes, and a reduced portion of alkylated aromatics, as compared to reformate.
Patent CA-2374665-A1 (CA)
Title: Chemical composition and method
Inventor: TENNEY JOEL D
IPC: C01B11/02
Filed: 2000-05-05
Abstract: The invention relates to a novel composition useful as a feed at production of chlorine dioxide, said composition being an aqueous solution comprising from about 1 to about 6.5 moles/litre of alkali metal chlorate, from about 1 to about 7 moles/litre of hydrogen peroxide and at least one of a protective colloid, a radical scavenger or a phosphonic acid based complexing agent, wherein the pH of the aqueous solution is from about 1 to about 4. The invention also concerns a process for producing chlorine dioxide using the novel composition.
Patent CA-2379995-A1 (CA)
Title: 11.beta.-aryl-17,17-spirothiolane-substituted steroids
Inventor: COOK EDGAR C
IPC: C07J33/00
Filed: 2000-07-20
Abstract: The invention is directed to a novel class of 11.beta.-aryl-17,17-spirothiolane-substituted steroid compounds exhibiting binding to the progestin receptor.
Patent CA-2381118-A1 (CA)
Title: An improved power saving function for wireless lans: methods, system and program products
Inventor: BEACH ROBERT
IPC: H04L12/56
Filed: 2002-04-09
Abstract: A wireless data communication system has a first station or mobile unit is linked to a second station configured as an access unit to support packet communication, voice or data, where the voice packets are transmitted in the Continuously Aware Mode (CAM) mode while other packets are buffered by the access point and held until asked for by the first station when in a Power Saving-Poll (PSP) mode. A monitoring apparatus at the access point monitors all transmitted packets and sorts the packets to the mobile unit according to CAM  or PSP mode.  Voice packets are sent out immediately to the mobile unit. Other packets are stored at the access point. The packet arrival rate may vary during transmission and due to random packet delays introduced by propagation characteristic and processing apparatus. The packet arrival rate and delays are taken into account by the first station in an algorithm to determine and extend the normal safe period in which the station receiver may be powered off.
Patent CA-2381718-A1 (CA)
Title: Joint prosthesis
Inventor: KRISHNAN JEGANATH
IPC: A61F2/46
Filed: 2000-09-14
Abstract: A prosthesis (2) for replacing a joint between first and second articulating bones (10, 12), the prosthesis comprising first and second joint members (4, 6) and wherein: the first joint member includes a first mounting member (26) which in use is mounted in an intramedullary canal (22) of the first bone; the second joint member includes a second mounting member (28) which in use is mounted in an intramedullary canal (27) of the second bone; the first joint member has a ball (30) having a first part spherical surface and a slot (34) extending transversely through the ball; the second joint member has a socket (52) having a second part spherical surface which is complementary to first spherical surface and a guide peg (60) which projects from the second spherical surface and in use is located in said slot; and wherein the guide peg is loose fit within the slot thereby permitting biaxial rotation of the second member relative to the first member about at least first and second axes (14, 16).
Patent CA-2385257-A1 (CA)
Inventor: KAWABE TAKUMI
IPC: C12N15/11
Filed: 2000-09-21
Abstract: L'invention concerne des compositions et des méthodes d'inhibition de kinases Chk1 et/ou Chk2. Elle concerne également des compositions et des méthodes d'inhibition du point de contrôle de l'arrêt cellulaire G2, notamment dans des cellules mammaliennes, par exemple, humaines. Lesdites compositions et méthodes de cette invention sont utilisées pour traiter des troubles de croissance cellulaire, tels que le cancer. Notamment, la présente invention concerne des méthodes de sensibilisation sélective des cellules cancéreuses altérées à point de contrôle G1 aux traitements et agents endommageant l'ADN. Elle a aussi trait à des méthodes de criblage de composés capables d'interagir avec des enzymes impliqués dans le point de contrôle de l'arrêt du cycle cellulaire G2, tel que la kinase Chk1 et/ou Chk2/Cds1, lesdits composés étant capables par exemple d'inhiber ces enzymes.
Patent CA-2387096-A1 (CA)
Inventor: EASTON MICHAEL J
IPC: F16K17/04
Filed: 2002-05-21
Abstract: A snap-type safety relief valve is provided that is designed for use under specified operating conditions on a pressure vessel or a flow line having a pressurized gas therein. The safety relief valve comprises: (a) a body attachable to the pressure vessel or flow line, the body comprising a chamber therein and an inlet and an outlet, the inlet comprising an inlet valve seat, the outlet being adapted to attach to outlet piping; (b) a disk member closable on the inlet valve seat; (c) a mechanism in the body biasing the disk member to rest on the inlet valve seat with a set force such that when the pressure in the pressure vessel exceeds a set pressure resulting from the set force, the disk member is lifted from the inlet valve seat; and (d) a secondary orifice between the chamber and the outlet, the secondary orifice being sized so that gas flows from the inlet valve seat into the chamber in a sonic flow and so that gas flows from the chamber through the secondary orifice in a sonic flow when the valve opens due to a pressure in the pressure vessel or flow line exceeding the set pressure during testing under the specified operating conditions. A method of designing a low blow-down snap-type safety relief valve is provided, as is a method of relieving pressure from a pressurized system using a snap-type safety relief valve.
Patent CA-2388317-A1 (CA)
Inventor: GAMELIN MARTIN
IPC: F24F3/044
Filed: 2002-05-31
Abstract: An air duct valve arrangement for use ain an air circulation system comprising an air handler unit and an air treatment unit. The valve arrangement being disposed to prevent short-circuiting of the air treatment unit, but not to hinder the operation of the air handler unit.
Patent CA-2388402-A1 (CA)
Inventor: SILVER LAURENCE E
IPC: A01K87/00
Filed: 2002-05-31
Abstract: A tip to be placed on a fishing rod. Conventional fishing rods usually terminate in an "eye" or "roller" end on the fishing pole. A more proper term for the end attachment on a pole is a "terminal guide" rather than an "eye". They are made in several sizes to fit various size shapes on fishing poles, however, they follow the industry standard of 64ths of an inch, i.e. a number four is 4/64ths inch hollow. A key innovation of the present invention is that it is conical (tapered) on the outside so that if the line did wrap around the tip, all that is necessary to get the line to unwrap is to hold the tip downward so gravity will unwrap the line as it peels off. The inside is hollow and shaped to fit the distal end of a fishing pole. Additionally, they are much thinner in cross section than all existing Terminal Guides that have an "eye" at the end. It is this "eye" (and its braces) on the normal tip that acts as a holder of the wraps. One of the things that makes the present invention tip unique is that it eliminates the raised "eye" and/or rollers on normal poles that acts as bumps or snags to hold the fishing line as it wraps.
Patent CA-2388566-A1 (CA)
Inventor: MAHAJAN PRAMOND B
IPC: C12N15/82
Filed: 2001-01-05
Abstract: L'invention concerne des acides nucléiques mutM isolés et leurs protéines codées. La présente invention concerne également des méthodes et des compositions de modification des niveaux de mutM de maïs dans les plantes afin d'améliorer l'efficacité de transformation, la recombinaison homologue et/ou les modifications des gènes ciblés. L'invention concerne en outre des cassettes d'expression de recombinaison, des cellules hôtes, des plantes transgéniques, et des compositions d'anticorps.
Patent CA-2390055-A1 (CA)
Inventor: FRYDMAN LARRY G
IPC: A47C20/02
Filed: 2000-07-14
Abstract: A stress reducing device is defined by a dual use orthopedic pillow having a low density polyurethane foam outer region, a high density polyurethane foam middle region that are provided in removably attachable layers, so that the size of the device may be adjusted to accommodate different sizes and preferences of individual users.  The pillow advantageously includes leg clasps for securely engaging the inner thighs of an individual in a sideling position defined by a stem and a pair of crescent shaped buttresses. The buttresses resist rotation to the prone and supine lying positions. The high foam within the stem separates the knees to reduce spinal stress. Advantageously, a supine sleeping position is added by positioning said pillow under the legs to flatten out the spine while supporting the legs at the thigh and calf regions.
Patent CA-2390146-A1 (CA)
Inventor: TWYDELL ROLAND
IPC: B01J13/00
Filed: 2000-11-15
Abstract: A pesticidal composition comprises, as the sole pesticidally-active componen t, a storage-stable aerated gel composition comprising 30 to 97 % by weight of water, 0.2 to 5 % by weight of a gelling agent selected from xanthan gum, sodium alginate and neutralised carboxyvinyl polymer and 2 to 5 % by weight of a fine particulate hydrophobic silicone-treated silica having a surface area  of from 80 to 300 m2/g. The composition is in the form of fine particles of an aqueous gel containing the water and gelling agent, the surfaces of which fi ne particles are coated with a coating of the finely particulate hydrophobic silica. The composition is useful in a method of controlling pests, particularly insects and acarids.
Patent CA-2390618-A1 (CA)
Inventor: GOVARI ASSAF
IPC: A61B5/01
Filed: 2002-06-13
Abstract: A position sensor for a medical device comprises a core made of a high permeable material such as Wiegand effect material comprising a mixture of cobalt, vanadium, and iron. The position sensor has an outer diameter of approximately 0.4 mm and is used in a medical device having an outer diameter of approximately 0.67 mm.
Patent CA-2394592-A1 (CA)
Title: Intumescent floor opening frame
Inventor: WHITTY LARRY
IPC: F16L5/04
Filed: 2002-07-24
Abstract: A frame for bordering conduit access through a building floor has a rigid body portion and a lining of intumescent material on an interior surface of the rigid body portion. The intumescent material has sufficient expansion capacity to close off the opening through the frame under conditions which produce an intumescing of the lining. The rigid body portion itself is preferably made of a metallic material to enhance transfer of heat energy from the rigid body portion to the lining of the frame.
Patent CA-2398588-A1 (CA)
Inventor: RODRIGUES JOSE
IPC: B05D7/14
Filed: 2001-01-29
Abstract: The invention concerns a mobile arm (10) providing a displacement for controlling the object to be covered moving in a horizontal plane on a conveyor or the like, and at the free end of which is mounted a sprayer (17). The pivoting arm (10) is mounted on a base capable of being driven in rotational motion about a substantially horizontal axis (12) substantially perpendicular to the conveying axis. In a first embodiment, it provides a translation movement along a substantially vertical or horizontal axis of the rotary base (6) bearing the arm and in another embodiment, it produces an articulation forming a bend on the arm bearing the sprayer.
Patent CA-2398660-A1 (CA)
Title: Human cyr61
Inventor: YEUNG CHO-YAU
IPC: A61K38/27
Filed: 2001-01-31
Abstract: Polynucleotides encoding mammalian ECM signaling molecules affecting the cel l adhesion, migration, and proliferation activities characterizing such comple x biological processes as angiogenesis, chondrogenesis, and oncogenesis, are provided. Polypeptide compositions are also provided. The polypeptide compositions comprise mammalian ECM signaling molecules, peptide fragments, inhibitory peptides capable of interacting with receptors for ECM signaling molecules, and antibody products recognizing Cyr61. Also provided are method s for producing mammalian ECM signaling molecules, methods for using mammalian  ECM signaling molecules to screen for, and/or modulate, conditions and disorders associated with angiogenesis, chondrogenesis, and oncogenesis; and  ex vivo methods for using mammalian ECM signaling molecules to prepare blood  products. Additionally, modulators, such as peptide modulators, of an ECM signaling molecule activity are provided. Further provided are methods for screening for modulators of a Cyr61 polypeptide-integrin receptor interactio n, as well as methods of treating conditions and disorders associated with such  an interaction.
Patent CA-2402734-A1 (CA)
Title: Catalytic conversion of alkanes to alkenes
Inventor: LEGENDRE OLIVIER
IPC: C07C11/06
Filed: 2001-03-23
Abstract: A process for the catalytic reaction of a C2 to C5 alkane and a sulphur containing compound to produce the corresponding alkene and hydrogen sulphide wherein the reaction mixture is contacted with a catalyst at a temperature of from 300 to 650 ~C wherein the catalyst has a surface area greater than 100 square metres per gram.
Patent CA-2402844-A1 (CA)
Title: Peptide fragments of the equine arteritis virus m protein and their use in diagnostic tests
Inventor: JERONIMO CELIA
IPC: C07K14/08
Filed: 2001-03-16
Abstract: This invention relates to recombinant DNA and polypeptides encoded thereby which have use in the provision of diagnostic test kits and methods of diagnosis for equine arteritis virus (EAV).
Patent CA-2403104-A1 (CA)
Title: Multiple scale cement composite with positive and ductile setting in uniaxial tension
Inventor: ROSSI PIERRE
IPC: C04B28/02
Filed: 2001-03-09
Abstract: The invention concerns a fibre-containing cement composite whereof the cement matrix comprises a water/binder ratio less than 0.25, and consists of cement, granular elements, fine elements with pozzolanic reaction and a fluidising agent. The reinforcement consists of three types of fibres: a) metal fibres with length ranging between 15 and 25 mm, diameter ranging between 0.25 and 0.3 mm in a volume percentage ranging between 0.5 and 3 %; b) metal fibres with length ranging between 5 and 10 mm, diameter ranging between 0.15 and 0.2 mm, in a percentage between 4 and 7 %; c) 1.5 to 5 % of short metal fibres with length less than 3 mm. The uniaxial tensile strength of said composite is not less than 30 MPa. Its exhibits positive and ductile strain hardening behaviour in uniaxial tension.