baber/WOPTO huggingface dataset:
Patent DE-69433901-D1 (DE)
Inventor: HULTGREN SCOTT
IPC: A61P31/04
Filed: 1994-11-18
Granted: 2004-08-19
Abstract: Novel methods for the treatment and/or prophylaxis of diseases caused by tissue-adhering bacteria are disclosed. By interacting with periplasmic molecular chaperones it is achieved that the assembly of pili is prevented or inhibited and thereby the infectivity of the bacteria is diminished. Also disclosed are methods for screening for drugs as well as methods for the de novo design of such drugs, methods which rely on novel computer drug modelling methods involving an approximative calculation of binding free energy between macromolecules. Finally, novel pyranosides which are believed to be capable of interacting with periplasmic molecular chaperones are also disclosed.
Patent DE-69501226-D1 (DE)
Inventor: DEHENNAU CLAUDE
IPC: C08J7/18
Filed: 1995-04-11
Granted: 1998-01-29
Abstract: An article, esp. a film, printed with an ink intended for printing of PVC, has at least a surface region comprising at least one polyolefin that has been treated with oxygen and fluorine and is characterised by the presence in the surface of F and O in concns. such that the atomic ratio O/C measured by ESCA spectroscopy (Electron Spectroscopy for Chemical Analysis) measured at a depth of 1.5 nm is at least 0.00 and the atomic ratio F/C measured in the same way is at least 90% and at most 290% of the O/C ratio.
Patent DE-69502688-D1 (DE)
Inventor: DE SNOO PAUL
IPC: A23L17/00
Filed: 1995-11-22
Granted: 1998-07-02
Abstract: A method for processing fish, in particular salmon, wherein the fish is cut into parts and the fish parts are subsequently bonded together by treating them with a bonding agent preferably consisting of a mixture of fibrinogen and thrombin, characterized in that the fish is cut into slices, whereby said slices vary so little in thickness that when the slices are placed one on top of the other in a mould, with the bonding agent being provided between the respective slices, a massive column of fish is formed as a result of deformation whilst the structure of the slices is retained. <IMAGE>
Patent DE-69506884-D1 (DE)
Inventor: CLARKE MICHAEL JOHN
IPC: E06C7/18
Filed: 1995-06-15
Granted: 1999-02-04
Abstract: An extendable bracket (2) is attached to the underside of a ladder. Ballast is placed on the bracket and the bracket is adjusted for length as necessary. The bracket and ballast assist in securing the top of the ladder against its support and the bottom of the ladder on the ground. <IMAGE>
Patent DE-69517957-D1 (DE)
Inventor: ARTIS R
IPC: C07D409/10
Filed: 1995-02-16
Granted: 2000-08-17
Abstract: The disclosed hexenoic acid side-chain derivatives of mycophenolic acid are therapeutic agents advantageous in the treatment of disease states indicated for mycophenolic acid and/or mycophenolate mofetil, including immune, inflammatory, tumor, proliferative, viral or psoriatic disorders.
Patent DE-69523764-D1 (DE)
Inventor: WALZER FLEXER
IPC: C08F110/06
Filed: 1995-07-28
Granted: 2001-12-13
Abstract: PCT No. PCT/US95/09578 Sec. 371 Date Jul. 14, 1997 Sec. 102(e) Date Jul. 14, 1997 PCT Filed Jul. 28, 1995 PCT Pub. No. WO96/04319 PCT Pub. Date Feb. 15, 1996The invention is directed to a catalyst composition suitable for addition reactions of ethylenically and acetylenically unsaturated monomers comprising a metal oxide support having covalently bound to the surface thereof directly through the oxygen atom of the metal oxide an activator anion that is also ionically bound to a catalytically active transition metal cation compound. The invention includes a preparation process for the invention catalyst composition exemplified by reacting a Lewis acid, such as trisperfluorophenyl boron with residual silanol groups of a silica support, preferably then reacting with a Lewis base such as diethylaniline, so as to prepare a silica bound anionic activator that when combined with a suitable transition metal compound will protonate it so as to form the ionic catalyst system. Use of the invention catalyst to polymerize alpha-olefins is exemplified.
Patent DE-69525039-D1 (DE)
Inventor: STUART W DORSEY
IPC: C12N15/04
Filed: 1995-02-02
Granted: 2002-02-21
Abstract: The invention relates to a heterokaryotic filamentous fungus host capable of producing a heterologous heterodimer comprising at least two subunits. The heterokaryon contains a first and second nucleus; each nucleus contains an expression system for one subunit of the heterodimer. The heterokaryon is prepared by culturing together a first fungus host strain and a second fungus host strain that is homozygous with the first fungus host strain with respect to all heterokaryon compatibility alleles, wherein the first and second fungus host strains are cultured together under conditions wherein neither the first nor the second fungus strain can survive unless the heterokaryotic host is formed.
Patent DE-69526508-D1 (DE)
Inventor: BUTTERFIELD D
IPC: F04B43/12
Filed: 1995-09-08
Granted: 2002-05-29
Abstract: A pumping mechanism moving in movement increments is controlled to space those movement increments in direct proportion to the volume resulting from each movement increment. In a further aspect, movement increments are grouped to result in approximately equal volumes per group. The mechanism moves continuously through the movement increments in each group. Groups are spaced to result in approximately equal flow volumes per group. The number of groups decreases as the flow rate increases. The number of movement increments in each group and the volume of each group increase as the flow rate increases.
Patent DE-69529536-D1 (DE)
Inventor: FRANSSON IVAR
IPC: A47K11/00
Filed: 1995-12-21
Granted: 2003-03-06
Abstract: PCT No. PCT/SE95/01564 Sec. 371 Date Oct. 10, 1997 Sec. 102(e) Date Oct. 10, 1997 PCT Filed Dec. 21, 1995 PCT Pub. No. WO96/32047 PCT Pub. Date Oct. 17, 1996The invention relates to an incinerating toilet, having a basic structure (1) accommodating a preferably insulating block (5), which is rotatable in a horizontal plane, and provided with at least one recess (2, 2', 2'') in its upper surface, this recess opening out in register with at least one opening (3), capped by a lidded seat ring (4), in the upper surface of the structure. The recess (2, 2', 2'') accommodates an outer and an inner receptacle (6, 7) with a space (8) therebetween. An incinerating flame (9), or the like, and an air supply (10) are arranged via a sealing lid (11) over the recess when it is in a position rotated away from the place where the seat ring (4) is situated, this flame and air supply being together intended to incinerate waste deposited by the toilet user in the inner receptacle (7) simultaneously as the combustion gases occurring during incineration may be taken through the space (8), these gases dissipating more heat during their passage through the space for assisting in the vaporization of water and urine in the waste, before the gases reach atmosphere via an outlet (15).
Patent DE-69530487-D1 (DE)
Inventor: MANNING MONNA MARIE
IPC: A61K8/00
Filed: 1995-08-07
Granted: 2003-05-28
Abstract: Disclosed are conditioning compositions for the hair containing compounds of the formula (R<1>)(R<2>)N(CHCH2OC(O)R)2X<->; wherein R<1> is alkyl containing 1 to 6 carbon atoms; R<2> is alkyl containing 1 to 6 carbon atoms, or benzyl; X<-> is an anion; and R is alkyl and alkylene of 12 to 22 carbon atoms having 0 to 3 carbon-carbon double bonds, provided that at least 2 different chain lengths R are present and 0, 1 and 2 such double bonds are present.
Patent DE-69600203-D1 (DE)
Inventor: NIELSEN JAN S
IPC: C23F13/02
Filed: 1996-01-10
Granted: 1998-05-07
Abstract: An apparatus for corrosion protection of a water system is disclosed, where a hitherto unknown principle for the production of ions of alkaline sensitive metal is used. The apparatus comprises a container (1,14,17), fully or partly flown through by the water, connected as cathode and/or comprising at least one cathode (9,10), the apparatus being provided with at least one anode (3), wherein cathode and anode are connected to a DC source, characterized in that at least one electrode (4), comprising alkaline sensitive metal and electrically isolated from the cathode and the anode connected with the DC source, is provided such that at least a part of the electrical current running through the water from the anode to the cathode, is forced through the electrode comprising alkaline sensitive metal. <IMAGE>
Patent DE-69604598-D1 (DE)
Inventor: MCABEE MICHAEL
IPC: D06M13/432
Filed: 1996-12-11
Granted: 1999-11-11
Abstract: A process for sizing spun yarns by adding urea in an amount of about 10 to 50% by weight of the weight of a polyacrylamide polymer, wherein the polymer and urea are applied in an amount sufficient to impart a high order of abrasion resistance to the yarn.
Patent DE-69614375-D1 (DE)
Inventor: KATZ BRUCE E
IPC: A61K31/505
Filed: 1996-04-10
Granted: 2001-09-13
Abstract: A composition for the treatment of actinic keratoses includes 5-fluorouracil and an alpha hydroxy carboxylic acid. The composition may further include ancillary ingredients. A therapeutic method involving the composition and a kit for carrying out the treatment are also disclosed.
Patent DE-69614781-D1 (DE)
Inventor: VENTOSA DUNJO JUAN
IPC: E01B1/00
Filed: 1996-05-17
Granted: 2001-10-04
Abstract: The rubber Pan (6) has an asymmetry that varies the rigidities on the sides directly in proportion to the stresses applied by the concrete block (4) due to the wheel-rail interaction. The asymmetrical variation can be achieved by decreasing the number of interspaces (8) between the ridges (7). The pan subject of the invention is applicable to double-block sleepers without a spacing bar in order to prevent pitching of the concrete block (4) and therefore gage widening of rails. <IMAGE>   <IMAGE>
Patent DE-69616824-D1 (DE)
Inventor: PEDERSEN E
IPC: B01D21/02
Filed: 1996-02-08
Granted: 2001-12-13
Abstract: PCT No. PCT/DK96/00063 Sec. 371 Date Nov. 19, 1997 Sec. 102(e) Date Nov. 19, 1997 PCT Filed Feb. 8, 1996 PCT Pub. No. WO96/25216 PCT Pub. Date Aug. 22, 1996A method and a basin serve the purpose of sedimenting sludge in waste water, which in a flow is supplied to the basin via an inlet and in clarified condition is removed via an outlet placed opposite to the inlet. In the inlet there has been built in resistances of flow which create a heavy turbulence in the water flowing and transform a substantial part of the energy of flow from the water into energy in the whirls which create the turbulence. Thereby there are created flow conditions which increase the creation of sludge flocs and the succeeding sedimentation of these.
Patent DE-69619272-D1 (DE)
Inventor: SANDMAN ANNIKA
IPC: C22C29/08
Filed: 1996-11-29
Granted: 2002-03-21
Abstract: PCT No. PCT/SE96/01579 Sec. 371 Date Sep. 1, 1998 Sec. 102(e) Date Sep. 1, 1998 PCT Filed Nov. 29, 1996 PCT Pub. No. WO97/20083 PCT Pub. Date Jun. 5, 1997A coated turning insert particularly useful for dry and wet machining in low and medium alloyed steels, stainless steels, with or without raw surface zones under severe conditions such as vibrations, long overhang and recutting of chips. The insert is characterized by a WC-Co cemented carbide with a low content of cubic carbides and a rather low W-alloyed binder phase and a coating including an innermost layer of TiCxNyOz with columnar grains and a top layer of TiN and an intermediate layer of  kappa -Al2O3. The layers are deposited by using CVD-methods.
Patent DE-69619882-D1 (DE)
Inventor: AMMANN NICO
IPC: A23L11/00
Filed: 1996-03-05
Granted: 2002-04-25
Abstract: Mfr. of textured proteins comprises dispersing soya flour, powder or flakes having granulometry 40-400 mu m and an acidifying agent in water at 10-30 degrees C to obtain a mixt. having dry matter content 33-40%, pH 4.8-5.7 and viscosity 5000-12000 mPas; subjecting the mixt. to treatment by steam injection for 5-60s at 120-150 degrees C to form textured pieces and ejecting them, via an ejection nozzle, in the form of distinct pieces; agglomerating the ejected pieces by impact on a deflecting surface which intercepts them so as to form a sausage of agglomerated pieces; shaping and/or cutting the sausage; and drying the prod.
Patent DE-69632393-D1 (DE)
Inventor: VALENTE A
IPC: G01N21/87
Filed: 1996-01-23
Granted: 2004-06-09
Abstract: A device and method for grading gemstones. The device utilizes an band pass filter and detector array to obtain the spectral response of a complete image. The gemstone is illuminated in a way that provides for analysis of both reflected and transmitted light. The device utilizes multiple lighting angles to construct an composite image that is used to perform the grading of the gemstone. The device provides spectral photometric data for each individual pixel of the image, or any portion of the gemstone image.
Patent DE-69637012-D1 (DE)
Inventor: DORIN GLENN J
IPC: A23L21/15
Filed: 1996-06-07
Granted: 2007-05-16
Abstract: Aqueous formulations of TFPI (tissue factor pathway inhibitor) include L-arginine and/or a solubilising agent selected from the group consisting of: an acetate ion; a sulfate ion; sodium chloride; a citrate ion; an isocitrate ion; glycine; glutamate; a succinate ion; histidine; imidazole; sodium dodecyl sulfate; or a charged polymer. The invention facilitates the solubilization, formulation, purification and refolding of TFPI. <IMAGE>
Patent DE-69638145-D1 (DE)
Inventor: KNECHTLE STUART J
IPC: A61K35/28
Filed: 1996-04-12
Granted: 2010-04-22
Abstract: Provided is a method of treating an immune system disorder not involving T-cell proliferation, comprising administering to the animal an immunotoxin comprising a mutant diphtheria toxin moiety linked to an antibody moiety which routes by the anti-CD3 pathway, or derivatives thereof under conditions such that the disorder is treated. Thus, the present method can treat graft-versus-host disease. Also provided is a method of inhibiting a rejection response by inducing immune tolerance in a recipient to a foreign mammalian donor tissue or cells, comprising the steps of: a) exposing the recipient to an immunotoxin so as to reduce the recipients' peripheral blood T-cell lymphocyte population by at least 80 %, wherein the immunotoxin is anti-CD3 antibody linked to a diphtheria protein toxin, wherein the protein has a binding site mutation; and b) transplanting the donor cells into the recipient, whereby a rejection response by the recipient to the donor organ cell is inhibited, and the host is tolerized to the donor cell.
Patent DE-69704819-D1 (DE)
Inventor: BELTRANI GIOVANNI BATTISTA
IPC: A63B33/00
Filed: 1997-08-08
Granted: 2001-06-21
Abstract: Swimming or diving goggles comprising a one- or two-curved-lens system (1a, 1b) having a progressive cornerless curvature of cylindrical type with vertical axes and variable radius, without curvature in the vertical plane and described by a peculiar geometrical law, according to which the front portion (3a, 3b) located in front of the user's eyes (E1, E2) has a curvature radius not less than 130 mm, and the two lateral portions (4a, 4b) have a lower curvature radius, anyway not less than 25 mm. The distance of the lens or lenses (1a, 1b) from the user's face is extremely reduced and such that two rays (r, s) coming out from the eyes (E1, E2) and lying on the horizontal plane intersect the lens or lenses (1a, 1b) at two point (R, S) such that the perpendiculars (NR, NS) to the inner surface of the lens or lenses (1a, 1b) at those two points (R, S) form an angle (D) not greater than 30 DEG  therebetween. <IMAGE>
Patent DE-69707611-D1 (DE)
Inventor: BRYANT HENRY UHLMAN
IPC: C07C45/65
Filed: 1997-08-27
Granted: 2001-11-29
Abstract: The instant invention provides dihydronaphthalene and naphthalene compounds, intermediates, formulations, and methods for use in the treatment of bone loss or bone resorption . The dihydronaphthalene compounds have the formula: <CHEM>  wherein   R<1> is -H, -OH, -O(C1-C4 alkyl), -OCO(C1-C6 alkyl), -O-CO-O(C1-C6 alkyl) , -O-CO-Ar, -OSO2(C2-C6 alkyl), -O-CO-OAr, where Ar is optionally substituted phenyl; R<2> is -H, -Cl, -F, C1-C4 alkyl, -OH, -O(C1-C4 alkyl), -OCO(C1-C6 alkyl), -O-CO-O(C1-C6 alkyl), -O-CO-Ar,-OSO2(C2-C6 alkyl), or -O-CO-OAr, where Ar is optionally substituted phenyl; R<3> and R<4> are, independently, R<2>, with the proviso that both R<3> and R<4> are not both. hydrogen. R<5> is 1-piperidinyl, 1-pyrrolidinyl, methyl-1-pyrrolidinyl, dimethyl-l-pyrrolidino, 4-morpholino, dimethylamino, diethylamino, diisopropylamino, or 1-hexamethyleneimino; and   n is 2 or 3; or a pharmaceutically acceptable salt or solvate thereof.
Patent DE-69711682-D1 (DE)
Inventor: JONES HENRY
IPC: G01S11/00
Filed: 1997-12-04
Granted: 2002-05-08
Abstract: A system for determining the position of each of a plurality of objects in a specified environment by determining the transit times of slowly propagating measurement energy transmitted from a measurement energy transmitter on each object to a plurality of fixed measurement energy receivers in the specified environment, the transmission of the measurement energy being triggered by a burst of high speed propagating trigger energy into the specified environment from a trigger energy transmitter, the measurement energy transmitter on each object being triggered by an object-mounted trigger energy receiver, each burst of trigger energy being encoded so as to trigger one only of the measurement energy transmitters, wherein a coordinating control system determines the order in which the measurement energy transmitters are triggered, in response to updatable information relating to service demands of the trigger energy transmitter and/or objects.
Patent DE-69716947-D1 (DE)
Inventor: BUSER THOMAS
IPC: A61K9/00
Filed: 1997-08-12
Granted: 2002-12-12
Abstract: A topical spreadable composition comprising 5-aminosalicylic acid (5-ASA) as active and monoolein is provided for treatment ulcers, inflammation and lesions of the oral cavity. The composition is spread over and adheres to the lesion, and is preferably prepared in a water free state. Examples of indications that can be treated are oral Crohn's Disease, apthous ulcers, orofacial granulomatosis, oral ulcers associated with Behet's disease and oral lichen planus.
Patent DE-69720227-D1 (DE)
Inventor: BRAUN MARCEL
IPC: A23L33/18
Filed: 1997-12-12
Granted: 2003-04-30
Abstract: A liquid protein hydrolysate-based food is made by partial enzymatic hydrolysis of a protein-containing starting material, packaging under sterile conditions and completing the hydrolysis in the packaging container. A process for producing a food product based on a protein hydrolysate in liquid form comprises: (a) adjusting the pH of a liquid non-hydrolyzed or partially hydrolyzed protein-containing starting material to a value of 6 - 9 by addition of a base before or after sterilization, in the latter case by addition of a sterilized base; (b) adding, under aseptic conditions, a proteolytic enzyme in an amount sufficient to provide the required degree of hydrolysis of the protein in the starting material; (c) packaging the hot material under aseptic conditions and hermetically sealing the packaging containers; and (d) allowing the packaged mixture to complete the hydrolysis within the packaging container.
Patent DE-69726868-D1 (DE)
Inventor: BOGOSIAN GREGG
IPC: C07K14/54
Filed: 1997-07-17
Granted: 2004-01-29
Abstract: A method for producing recombinant peptides and proteins having a diminished retention of N-formyl-methionine by coexpressing a peptide deformylase enzyme is disclosed. Also disclosed are substantially deformylated protein compositions and transformed bacterial cells and DNA vectors useful for acheiving such deformylation.
Patent DE-69728188-D1 (DE)
Inventor: GALLAGHER M
IPC: C22C38/04
Filed: 1997-09-18
Granted: 2004-04-22
Abstract: High strength steel structural members and a method of making same are disclosed by providing high-strength steel material having a specific chemical composition and preferably a tensile strength of at least about 120,000 psi and a yield strength of at least about 90,000 psi and hot rolling the steel material to provide the structural member of desired geometric configuration.
Patent DE-69728695-D1 (DE)
Inventor: MOLANDER DAN
IPC: B29C45/16
Filed: 1997-09-02
Granted: 2004-05-19
Abstract: A method of forming a stackable plastic box blank is described. A net of hinged elements are formed from a first plastic material. A plurality of panels are formed from a second plastic material, with the panels located between the individual elements of the net. The individual panels are then bonded or fused to the hinge elements.
Patent DE-69734408-D1 (DE)
Inventor: RUSELL DAVID B
IPC: B29C67/00
Filed: 1997-12-19
Granted: 2006-03-02
Abstract: Apparatus (3) and method for 3D-printing wherein the volume of applied binder deposited to selected positions in the layer of build material varies.
Patent DE-69806900-D1 (DE)
Inventor: ANSTICE MARY
IPC: A61K6/891
Filed: 1998-01-12
Granted: 2002-09-05
Abstract: A polymerisable cement composition, particularly for dental and biomedical uses, comprises a mixture of polymerisable monomer materials including between 5 and 95% by weight tetrahydrofurfuryl methacrylate (THFMA), and at least 5% by weight secondary monomer, preferably a dimethacrylate; and active filler material, preferably powdered fluoroaluminosillicate glass, capable of undergoing an acid-base reaction in the presence of water with acid or acid derivative groups in the composition. The composition is conveniently in the form of a resin-modified glass-ionomer cement or a compomer composition. The use of THFMA as a monomer material has a number of advantages. THFMA has low shrinkage on polymerisation, good biological acceptability and advantageous water uptake properties in comparison to other monomer systems. The invention also covers a method of preparing a polymerisable cement, and a method of dental treatment.
Patent DE-69807688-D1 (DE)
Inventor: DEVERA L
IPC: C07C211/54
Filed: 1998-06-05
Granted: 2002-10-10
Abstract: This invention provides a method for preparing 4-ADPA by charging nitrobenzene into a reaction zone under hydrogen pressure in the presence of a strong organic base and a catalyst for hydrogenation. The method provides the convenience and economy of a one-step process, while producing improved yields and selectivities. The invention further provides for various embodiments of the foregoing which are suitable for the production of 4-ADPA, and the hydrogenation or reductive alkylation to produce PPD. Important to the invention are the molar ratios of aniline to nitrobenzene and nitrobenzene to the strong organic base and the choice and use of hydrogenation catalyst.
Patent DE-69814146-D1 (DE)
Inventor: BIEDERMANN ANNE
IPC: A61K31/35
Filed: 1998-10-14
Granted: 2003-06-05
Abstract: The present invention relates to methods for inhibiting sebaceous gland activity in mammalian skin comprising administration of a topical composition comprising dehydroacetic acid or pharmaceutically acceptable salts thereof, and a dermatologically-acceptable carrier. The present invention also relates to methods and topical compositions further comprising agents which regulate the oily and/or shiny appearance of skin, and agents which treat acne and related skin disorders in mammalian skin and scalp. Methods of reducing sebum synthesis with the use of dehydroacetic acid, methods of regulating the oily and/or shiny appearance of skin, and methods of treating acne and other skin disorders are also encompassed by the present invention.
Patent DE-69818029-D1 (DE)
Inventor: BEALIN-KELLY JOSEPH
IPC: A61K36/18
Filed: 1998-04-14
Granted: 2003-10-16
Abstract: A throat drop comprises from 60% to 95% of an edible shell and from 5% to 40% of an aqueous filling, by weight of the drop. The filling contains a throat relief agent, from 8% to 95%, by weight, water and from 0.001% to 10%, by weight, of a vesicle-forming agent which encapsulates the throat relief agents with vesicles which are dispersed within the filling. The vesicles have a number average particle size of from about 1 to about 100 mum.