baber/WOPTO huggingface dataset:
Patent EP-4094988-A1 (EP)
Title: Vehicle lighting fixture
Inventor: YAMAMOTO NORIMASA
IPC: F21W103/55
Filed: 2021-01-13
Abstract: Multiple light sources 10 are arranged in an array. A light guide member 20 receives light emitted from the multiple light sources 10 on its back face, and outputs the light thus received from its front face. The light guide member 20 has a base portion 22 such that its back face 22a faces the multiple light sources 10 and such that it extends in the array direction of the multiple light sources 10. Multiple back-face protrusions 24 and multiple front-face protrusions 26 are formed such that they protrude from the back face 22a and the front face 22b of the base portion 22. The front-face protrusion 26 has multiple continuous faces in the circumferential direction along the front face 22b of the base portion 22.
Patent EP-4178481-A1 (EP)
Inventor: SIEBENHAAR GUILLERMO LEONARDO
IPC: A61B46/20
Filed: 2021-07-07
Abstract: A protective barrier (1) for face isolation in orotracheal maneuvers, comprising: an essentially rectangular sheet (2) made of a clear plastic material comprising, on its back side, a plurality of first circumferentially arranged fastening means and second cross- sectionally arranged fastening means substantially dividing the sheet (2) in half thereby defining two sections (5); and at least four sleeves (6) made of a clear plastic material affixed to the sheet (2) in one of the sections (5) defined by the second cross-sectionally arranged fastening means defining an outwardly open arc, wherein said sleeves comprise third fastening means (7) arranged internally and circumferentially on the distal ends of each of the sleeves.
Patent EP-4238077-A1 (EP)
Inventor: PETROVIC ANDREAS
IPC: G08G/
Filed: 2021-07-27
Abstract: Die Erfindung betrifft ein Verfahren zur Bereitstellung von mittels fahrzeugeigenen Sensoren erfassten Informationen über Verkehrsteilnehmer (T1, T2) in einem Fahrzeugumfeld. Erfindungsgemäß werden die erfassten Informationen als Vektoren repräsentierende Datenstrukturen (D) bereitgestellt. Jeder Vektor wird dabei einer Zelle (B1 bis Bn, BB1 bis BBm) eines vorgegebenen fahrzeugfesten Belegungsgitters (B, BB), in welcher sich ein von den jeweiligen Informationen beschriebener Verkehrsteilnehmer (T1, T2) befindet, zugeordnet. Jeder Vektor umfasst zumindest Koordinaten einer zugeordneten Zelle (B1 bis Bn, BB1 bis BBm), in welcher sich der jeweilige Verkehrsteilnehmer (T1, T2) befindet, einen Geschwindigkeitsvektor, welcher eine Geschwindigkeit (v) des jeweiligen Verkehrsteilnehmers (T1, T2) repräsentiert, einen Zeitstempel, welcher einen Zeitpunkt (t1, t2) einer Erfassung des jeweiligen Verkehrsteilnehmers (T1, T2) repräsentiert, und eine Objektklasse, welche einen Typ des jeweiligen Verkehrsteilnehmers (T1, T2) repräsentiert. Die Erfindung betrifft weiterhin ein Verfahren zum Betrieb eines automatisiert betreibbaren Fahrzeugs (F1, F2).
Patent EP-4178594-A1 (EP)
Inventor: GKOUTI ASIMINA
IPC: A61K35/34
Filed: 2021-07-12
Abstract: A method for generating a three-dimensional neuromuscular organoid in vitro is disclosed. This method comprises the following steps: a) providing a first cell culture comprising disease- specific neuromesodermal progenitor cells, wherein 30 % to 90 % of the disease-specific neuromesodermal progenitor cells co-express BRACHYURY/SOX2 and 10 % to 70 % of the disease-specific neuromesodermal progenitor cells co-express TBX6, and cultivating the disease-specific neuromesodermal progenitor cells in a first differentiation medium chosen from the group consisting of i) a non-supplemented serum-free cell culture medium and ii) a serum-free cell culture medium supplemented with at least one of a ROCK inhibitor, an activator of a growth factor signaling pathway, and an activator of an insulin signaling pathway; b) replacing the first differentiation medium by a second differentiation medium within 1 to 3 days after cultivation start, wherein the second differentiation medium is chosen from the group consisting of i) a non-supplemented serum-free cell culture medium and ii) a serum-free cell culture medium supplemented with at least one of an activator of a growth factor signaling pathway, and an activator of an insulin signaling pathway; c) replacing the second differentiation medium by a non-supplemented serum-free cell culture medium within 1 to 3 days after replacing the first differentiation medium by the second differentiation medium; and d) obtaining a three-dimensional neuromuscular organoid from the non-supplemented serum- free cell culture medium.
Patent EP-4100025-A1 (EP)
Inventor: DANIYAN ANTHONY
IPC: A61P35/00
Filed: 2021-02-05
Abstract: The present disclosure provides methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to chimeric antigen receptors (CARs) comprising a mutated CD28 intracellular motif, and cells comprising such CARs. The presently disclosed subject matter further relates to the use of said cells for treating diseases, e.g, for treating cancers.
Patent EP-4104008-A1 (EP)
Title: Freeform contact lenses for myopia management
Inventor: BAKARAJU RAVI CHANDRA
IPC: G02C7/04
Filed: 2021-02-06
Abstract: The present disclosure relates to a contact lens for managing myopia wherein the contact lens comprises of an optical zone about an optical axis and a non-optical peripheral carrier zone about the optical zone; wherein the optical zone is configured with a substantially single vision power profile providing correction for the eye, and a decentred second region configured with one or more meridionally and azimuthally variant power distributions, wherein at least one of the meridionally and azimuthally variant power distribution is devoid of mirror symmetry, the second region located substantially away from the optical centre and configured to provide at least in part a regional conoid of partial blur producing an optical stop signal for the eye; and wherein the non-optical peripheral carrier zone is configured with a thickness profile that is substantially rotationally symmetric to further provide a temporally and spatially varying stop signals to reduce myopia progression.
Patent EP-4085131-A1 (EP)
Inventor: CHEN HONGLIN
IPC: C12N7/01
Filed: 2021-02-05
Abstract: L'invention concerne des virus vivants atténués contre le nouveau coronavirus Sars-CoV-2. Les souches de virus chimériques atténués vivants sont basées sur un virus de la grippe atténué vivant (LAIV), utilisé en tant que squelette maître, qui comprend la délétion de l'élément de virulence virale, la NS1 (protéine non structurale 1) (DeLNS1), modifié pour exprimer un ou plusieurs antigènes du Sars-CoV-2 (ici CoV2Ag). La souche virale chimérique présente de préférence une adaptation à froid spontanée avec une préférence pour croître à entre 30 et 33 °C. La souche DelNS1-Sars-CoV-2-CoV2Ag peut être utilisée pour protéger un sujet qui en a besoin, contre une infection à Sars-CoV-2.
Patent EP-4217600-A1 (EP)
Title: Ensemble comprenant un filtre a air et une vanne de dosage d'air
Inventor: REZOUG AMINE
IPC: F02M35/02
Filed: 2021-07-13
Abstract: La présente concerne un ensemble (1) comprenant un filtre à air (2) comprenant un couvercle (7), ce couvercle (7) comprenant une ouverture (9), une vanne de dosage d'air comprenant une entrée d'air filtré, un joint d'étanchéité (15) disposé entre l'ouverture (9) et l'entrée d'air filtré, caractérisé en ce qu'il comprend des moyens d'indexation du joint d'étanchéité (15) par rapport au couvercle (7).
Patent EP-4205453-A1 (EP)
Inventor: XUE YISHENG
IPC: H04W52/02
Filed: 2021-07-22
Abstract: Des systèmes et des procédés de communication sans fil associés à une économie d'énergie d'une liaison aval d'une topologie en étoile d'un équipement utilisateur (UE) sont fournis. Selon certains aspects, un premier UE peut surveiller la liaison aval connectant un second UE au premier UE pour un message de commande transmis par le second UE au premier UE. Le premier UE peut ensuite établir un mode opérationnel sur la base du résultat de la surveillance du message de commande, tel que, mais sans y être limité, un mode d'économie d'énergie ou un mode actif.
Patent EP-4204363-A1 (EP)
Inventor: ARMSTRONG PAUL B
IPC: C01F17/206
Filed: 2021-08-06
Abstract: A method of making surface-functionalized transition metal oxide nanoparticles comprises: providing a sol comprising transition metal oxide nanoparticles dispersed in an aqueous liquid medium having a pH of less than or equal to 3.5, combining the sol with an extractant composition comprising at least one carboxylic acid and at least one organic amine, and a water-immiscible organic solvent, and separating at least a portion of the organic phase from the aqueous phase and then at least partially removing the water-immiscible organic solvent. The carboxylic acid has from 6 to 30 atoms. The organic amine is represented by the formula R2R3NH, wherein R2 is a hydrocarbyl group having from 6 to 30 carbon atoms, and R3 is H or an alkyl group having from 1 to 4 carbon atoms. The at least one organic amine is present in an amount sufficient raise the pH to at least 5, thereby forming discrete separable aqueous and organic phases. A surface-modified nanoparticle composition, a curable composition and an article comprising the same are also disclosed.
Patent EP-4106781-A1 (EP)
Title: Virus myxomateux recombinants et leurs utilisations
Inventor: MOUSSES SPYRO
IPC: A61K39/275
Filed: 2021-02-19
Abstract: La présente invention concerne un virus myxomateux oncolytique recombinant modifié pour exprimer une forme soluble d'une protéine de point de contrôle immunitaire conjointement avec une cytokine/chimiokine et/ou un antigène tumoral. Dans certains aspects, le virus myxomateux oncolytique est un virus compétent de réplication tel que le virus du myxome. L'invention concerne également des procédés de traitement du cancer comprenant l'administration du virus myxomateux oncolytique recombinant exprimant la forme soluble de la protéine de point de contrôle immunitaire.
Patent EP-4095671-A1 (EP)
Inventor: ZHOU XINGCHEN
IPC: G06F3/14
Filed: 2021-02-09
Abstract: This application provides a projection method and a terminal device, and is applicable to the field of projection technologies. The method includes: responding to a screen projection instruction, and obtaining a real-time interface of an application program on which screen projection is to be performed and device information of one or more receive ends; scoring a visual effect, a sound effect, and interaction complexity of a receive end based on the device information, to obtain a user experience score; obtaining, from the real-time interface based on the user experience score, first data on which screen projection is to be performed and that corresponds to each receive end; when the first data on which screen projection is to be performed includes the user interface control, obtaining a control layout file of the user interface control; and sending the first data on which screen projection is to be performed and the control layout file to the corresponding receive end, so that each receive end generates a corresponding display interface based on the received first data on which screen projection is to be performed and the received control layout file. In embodiments of this application, a projection manner with more abundant functions and more flexible operations can be implemented.
Patent EP-4110179-A1 (EP)
Inventor: PURVES CHRISTOPHER QUENTIN
IPC: A61B5/087
Filed: 2021-01-28
Abstract: An apparatus and method for collecting a breath sample are provided. The apparatus has a breath input interface configured to receive exhaled breath, a container connected to the breath input interface for receiving at least some of the exhaled breath, the container having a cavity with a volume that is controllable, and at least one controller configured to control the volume of the cavity to increase at a volume increase rate that is at most equal to a flow rate of the exhaled breath received by the breath input interface.
Patent EP-4122462-A1 (EP)
Inventor: LIU XIBAO
IPC: A61P35/00
Filed: 2021-03-19
Abstract: The present application provides application of butylphthalide or optical isomer, prodrug, deuterium, metabolite, and ring-opening product or ring-opening product salt thereof in the preparation of a drug for preventing, alleviating, or treating peripheral neuropathy, especially chemotherapy-induced peripheral neuropathy, and a use method of butylphthalide and a derivative thereof in preventing or treating peripheral neuropathy, especially chemotherapy-induced peripheral neuropathy. In vivo and in vitro studies show that the drug of the present invention can effectively prevent, alleviate, or treat peripheral neuropathy caused by chemotherapy drugs without affecting the tumor-inhibiting efficacy and pharmacokinetic properties of the chemotherapy drugs.
Patent EP-4208472-A1 (EP)
Inventor: VAN DER LEY PETER ANDRÉ
IPC: C07K14/235
Filed: 2021-09-03
Abstract: The invention pertains to a mutant  Bordetella  OmpA polypeptide. A  Bordetella  comprising said mutant polypeptide has a high blebbing phenotype. Hence, the invention further pertains a method for producing OMVs, wherein the method comprises a step of culturing a population of  Bordetella  bacteria comprising a modified OmpA polypeptide, under conditions conductive for the production of OMVs. In addition, the invention pertains to OMVs produced by a  Bordetella  comprising a mutant OmpA polypeptide, and the use of such OMVs for the treatment and prevention of a  Bordetella  infection.
Patent EP-4203780-A1 (EP)
Title: Method and system for displaying heart rate variability
Inventor: ADDISON PAUL S
IPC: A61B5/00
Filed: 2021-08-24
Abstract: According to an aspect, a method and system for displaying heart rate variability on a display device includes obtaining patient heart rate variability from heart rate information. At least one indicator corresponding to the heart rate variability is superimposed over the heart rate variability on the display device and used to determine a patient status. The patient status is identified as it corresponds to the at least one indicator, such as a color, and communicated to a clinician. The device therefore provides a visual indication of patient status based on the graphic display of the heart rate variability. A minimum threshold value for the heart rate variability is indicated on the display device. An alarm is activated when the minimum threshold value of the heart rate variability is reached and deactivated when the heart rate variability exceeds the minimum threshold value.
Patent EP-4213720-A1 (EP)
Title: Device for measuring an inner width of a pocket arranged in a surgical plane deep to the skin or underlying tissue
Inventor: THORFINN JOHAN
IPC: A61B5/107
Filed: 2021-09-13
Abstract: Device (1) for measuring an inner width (D) of a pocket (11) arranged in a surgical plane deep to the skin or underlying tissue. The device comprises two legs (2, 3), each having a first leg portion (2a, 3a) and a second leg portion (2b, 3b) fixed to each other at a joint connection (2c, 3c). The legs (2, 3) being connected to each other at the joint connections (2c, 3c), such that the legs (2, 3) are pivotable relative each other in a plane (XY), such that when end portions (2a2, 3a2) of the two first leg portions (2a, 3a) are moved towards each other in the plane (XY), end portions (2b2, 3b2) of the second leg portions (2b, 3b) are caused to move apart from each other in the plane (XY). A distance reader (6) gives a distance (B) between abutment surfaces of the end portions (2b2, 3b2) of the second leg portions (2b, 3b) in the plane (XY). An angle (D2, D3) between the first and second leg portions (2a, 3a; 2b, 3b) of each leg (2, 3) at the joint connection (2c, 3c) is 90 to 150 degrees.
Patent EP-4129056-A1 (EP)
Inventor: KAWAI SHIGEKAZU
IPC: A01K67/033
Filed: 2021-02-26
Abstract: There is provided a rearing apparatus for rearing an organism includes: a box-shaped rearing case; at least one perching member that is held in the rearing case and that is capable of perching the organism; and a separating member that is provided in the rearing case and that is movable along the perching member. The separating member is configured to separate the organism perched at the perching member from the perching member by the separating member moving along the perching member.
Patent EP-4131342-A1 (EP)
Title: Wide gap semiconductor device and method for manufacturing wide gap semiconductor device
Inventor: MAEYAMA YUSUKE
IPC: H01L21/28
Filed: 2021-03-23
Abstract: A wide gap semiconductor device has: a wide gap semiconductor layer; and a metal layer 20 provided on the wide gap semiconductor layer. The metal layer 20 has a single crystal layer 21 in an interface region at an interface with the wide gap semiconductor layer. When it is assumed that a lattice constant, in an equilibrium state, of a metal constituting the metal layer 20 is L, the single crystal layer 21 in the interface region includes a first region in which a lattice constant L1 is smaller than L by 1.5% to 8%.
Patent EP-4211244-A1 (EP)
Title: Compositions and methods for cd38 modification
Inventor: LYDEARD JOHN
IPC: C12N15/113
Filed: 2021-09-14
Abstract: Provided herein are gRNA comprising a targeting domain that targets CD38, which may be used, for example, to make modifications in cells. Also provided herein are methods of genetically engineered cell having a modification (e.g., insertion or deletion) in the CD38 gene and methods involving administering such genetically engineered cells to a subject, such as a subject having a hematopoietic malignancy.
Patent EP-4137832-A1 (EP)
Inventor: HUANG QIANG
IPC: A61B1/04
Filed: 2021-04-12
Abstract: The present invention discloses a method for establishing an effective magnetic connection. The method includes a step of effective magnetic connection judgment and a step of effective magnetic connection establishment. When the effective magnetic connection is established, one of the following manners is adopted: Manner 1 is performing searching on planes with different heights, and finding a position where a greatest magnetic field value meets a magnetic field establishment threshold of the effective magnetic connection in the planes to establish the effective magnetic connection; Manner 2 is finding the position where the greatest magnetic field value meets the magnetic field establishment threshold of the effective magnetic connection according to a solution of performing searching in a local space to establish the effective magnetic connection; and Manner 3 is directly moving an auxiliary magnetic sensor array to a position with a relative distance meeting Δd to establish the connection. The present invention further provides an apparatus for establishing an effective magnetic connection. The use of the present invention can ensure that a mobile magnetic source is always in a range of being effectively driven and detected during movement in a large working space.
Patent EP-4264093-A1 (EP)
Inventor: MAISCH DIETER
IPC: F16K11/044
Filed: 2021-10-13
Abstract: L'invention concerne un ensemble soupape proportionnelle (100) pour des fluides frigorigènes, comprenant un boîtier de soupape (110) ayant une chambre de corps de soupape (105), un corps de soupape (120) qui est disposé à l'intérieur de la chambre de corps de soupape (105) et est conçu pour pouvoir être transféré entre une première position et une seconde position, le boîtier de soupape (110) ayant un premier siège d'étanchéité (112) et un second siège d'étanchéité (114) et le corps de soupape (120) pouvant être transféré entre le premier siège d'étanchéité (112) et le second siège d'étanchéité (114).
Patent EP-4214188-A1 (EP)
Inventor: MAHAPATRA TRIDIB
IPC: C07C227/02
Filed: 2021-09-16
Abstract: La présente invention concerne un procédé de synthèse d'un composé de formule (Z) ou un sel de celui-ci, formule dans laquelle R, R1, R2, R3 et R10 sont tels que définis dans la description détaillée. Le procédé comprend en outre la synthèse d'un composé diamide anthranilique de formule (I).
Patent EP-4148819-A1 (EP)
Inventor: ZHANG BAOHAI
IPC: H01M4/131
Filed: 2021-04-29
Abstract: The present application provides a positive electrode sheet, a preparation method thereof, and a lithium-ion battery including the positive electrode sheet. The positive electrode sheet includes a positive electrode current collector, and the positive electrode current collector includes a single-sided coated area and a double-sided coated area. In the single-sided coated area, a first coating layer is disposed on a first surface of the positive electrode current collector, the first coating layer includes a first positive electrode active material layer and a second positive electrode active material layer, the second positive electrode active material layer is disposed on the surface of the positive electrode current collector, and the first positive electrode active material layer is disposed on a surface of the second positive electrode active material layer, and a particle size of the first positive electrode active material is larger than a particle size of the second positive electrode active material. The lithium-ion battery including the positive electrode sheet has the following effects: it can effectively improve the problem of lithium precipitation in the single-sided coated area of a negative electrode of the lithium-ion battery having a conventional spirally wound structure, thereby improving the cycle life of the lithium-ion battery, and reducing the cycle expansion of the lithium-ion battery. The compaction of a positive electrode is improved, and the energy density of a battery cell is increased without reducing the rapid charging performance of the battery.
Patent EP-4225872-A1 (EP)
Inventor: SEIFERMANN STEFAN
IPC: C09K11/06
Filed: 2021-10-11
Abstract: The invention pertains to an organic molecule for use in optoelectronic devices. The organic molecule has - a first chemical moiety with a structure of Formula I and - a second chemical moiety with a structure according to Formula II wherein the first chemical moiety is linked to the second chemical moiety via a single bond; # is the binding site of the first chemical moiety to the second chemical moiety; exactly one group selected from R a , R b , and R c  is the binding site of a single bond linking the second chemical moiety to the first chemical moiety; m is 0 or 1, n is 0 or 1, and m + n = 1; and wherein at least one pair of adjacent groups R I  and R II , R II  and R III , R III  and R IV , R V  and R VI , R VI  and R VII , R VII  and R VIII , R IX  and R X , R X  and R XI , R XI  and R XII  R XII  and R XIII , R XIV  and R XV , R XV  and R XVI , R XVI  and R XVII , R XVII  and R XVIII  forms an aromatic ring system which is fused to the adjacent benzene ring a, b, c or d of formula I and which is optionally substituted with one or more substituent R 9 .
Patent EP-4241221-A1 (EP)
Title: Web-based activation of contactless cards
Inventor: RULE JEFFREY
IPC: G06Q20/34
Filed: 2021-10-18
Abstract: Systems, methods, articles of manufacture, and computer-readable media. A computing device may wirelessly receive a network address for a resource from a contactless card that is in an inactivated payment state. A web browser executing on the computing device may access the resource at the network address. The resource in the web browser may operate a card reader of the computing device to receive a cryptogram from the contactless card. The resource in the web browser may transmit the cryptogram to a server. The resource in the web browser may receive, from the server, a response specifying that the contactless card has been transitioned from the inactivated payment state to an activated payment state.