baber/WOPTO huggingface dataset:
Patent CA-3144416-A1 (CA)
Title: Optimized bacteria engineered to treat disorders involving the catabolism of leucine, isoleucine, and/or valine
Inventor: LI NING
IPC: A61K35/74
Filed: 2020-06-19
Abstract: The present disclosure provides recombinant bacterial cells that have been engineered with genetic circuitry which allow the recombinant bacterial cells to sense a patient's internal environment and respond by turning an engineered metabolic pathway on or off. When turned on, the recombinant bacterial cells complete all of the steps in a metabolic pathway to achieve a therapeutic effect in a host subject. These recombinant bacterial cells are designed to drive therapeutic effects throughout the body of a host from a point of origin of the microbiome. Specifically, the present disclosure provides recombinant bacterial cells comprising a heterologous gene encoding an improved leucine catabolism enzyme with higher activity and/or specificity for leucine over other branched chain amino acids, such as isoleucine or valine. The disclosure further provides pharmaceutical compositions comprising the recombinant bacteria, and methods for treating disorders involving the catabolism of leucine, isoleucine, and/or valine using the pharmaceutical compositions disclosed herein.
Patent CA-3144837-A1 (CA)
Title: Blade pitch control
Inventor: MARGER THIBAUT
IPC: B64C11/40
Filed: 2022-01-05
Abstract: A blade pitch control assembly comprising a pitch control actuator (1) having a coarse actuator chamber having a coarse chamber area and a fine actuator chamber having a fine chamber area, the coarse chamber area being biased to a feather position, and a primary pitch control valve (2) configured to control the flow of pressurised fluid to the coarse actuator chamber and the fine actuator chamber, respectively via a coarse fluid line and a fine fluid line; the assembly further comprising a hydraulic protection system located between the actuator and the primary pitch control valve, configured to bypass the primary pitch actuator in response to a trigger; wherein the hydraulic protection system comprises a hydraulic protection system valve located between the coarse fluid line and the fine fluid line, wherein activation of the hydraulic protection system valve fluidly connects the coarse fluid line and the fine fluid line so as to balance fluid pressure between the coarse chamber and the fine chamber.
Patent CA-3147467-A1 (CA)
Inventor: MOCHRIE DOUGLAS
IPC: G06Q30/02
Filed: 2022-02-02
Abstract: Devices for symbiotic display of ads on mobile devices are provided. A mobile device has a display screen that includes an ad display for displaying ad content and an operating system display for operating system and applications. Ads are constantly displayed on the ad display independent to the content displayed on the operating system display. The display screen may have an aspect ratio of 18:9 with a 2:9 ad display and a 16:9 operating system display. The ad display and operating system display may be separate touch screens that are contiguous or a single touch screen that is divided into two or more distinct displays as a function of an operating system or application. The ad display may be in an auxiliary display device connected to the mobile device. A system and method for applying symbiotic targeted advertising is also provided.
Patent CA-3148284-A1 (CA)
Title: Unite d'affichage publicitaire et panneau d'antenne antivol
Inventor: CASTAGNE CHRISTOPHE JEAN DOMINIQUE
IPC: G08B13/24
Filed: 2020-07-21
Abstract: Une unité d'affichage publicitaire faisant appel à une antenne antivol comprend un corps d'antenne et un panneau d'antenne installé sur le corps d'antenne. Le panneau d'antenne comprend un recto et un verso. Le panneau d'antenne comprend un écran d'affichage sur le recto ou le verso. L'écran d'affichage peut être un écran à LED ou un écran LCD. L'écran d'affichage peut être opaque ou transparent.
Patent CA-3150405-A1 (CA)
Inventor: TANAKA SIMON
IPC: B29C64/386
Filed: 2020-07-29
Abstract: The present invention relates to a method of imposing quality requirements on a 3D model (1) including support structures (2) to be built by an additive manufacturing apparatus comprising: a platform (3) for holding the 3D object corresponding to the 3D model (1), the method comprising: a step of defining the surface geometry and the orientation of the 3D model (1) with respect to the platform (3), wherein the surface geometry includes surface segments; characterized by further comprising: a step of attributing a degree of quality (L;H) to the surface segments respectively against post-processing for the subsequent removal of the support structures (2); a step of calculating, based on the defined orientation, the surface geometry and the degree of quality (L;H) attributed, the positions on the surface segments where the support structure (2) may be added; and a step of adding the support structure (2) to the 3D model (1) based on the calculated positions and the degree of quality (L;H) attributed.
Patent CA-3151179-A1 (CA)
Title: Methods and systems for tracking a pipeline inspection gauge
Inventor: JALILIAN SEYED EHSAN
IPC: G01B17/00
Filed: 2021-08-06
Abstract: There is described a method of determining a position of a pipeline inspection gauge (PIG) in a fluid conduit. While the PIG is moving through the fluid conduit, one or more sensors positioned along the fluid conduit are used to detect one or more signals. Parameter data is extracted from the detected one or more signals. The parameter data includes one or more parameters of the detected one or more signals as a function of time and position along the fluid conduit. PIG movement data indicative of a position of the PIG in the fluid conduit as a function of time is generated using the parameter data.
Patent CA-3151301-A1 (CA)
Title: Disposable perforator
Inventor: UJVARI MIHALY GYULA
IPC: A61B17/16
Filed: 2019-07-25
Abstract: The invention relates to a disposable perforator (10) for drilling bone tissue, comprising: - a drive shaft (12) with rotation axis (t), - a drill head (14) having the same rotation axis (t) and being releasably coupled to the drive shaft (12), - a chipping head (16) arranged coaxially around the drill head (14) and being coupled therewith, the chipping head (16) having a proximal portion (161) receiving a distal portion (121 ) of the drive shaft (12), characterised in that a first groove (122) is provided along an external circumference of the distal portion (121 ) of the drive shaft (12) and a second groove (162) is provided along an internal circumference of the proximal portion (161 ) of the chipping head (16), the two grooves (122, 162) facing each other together define a ring shaped nest (92) when the proximal portion (161 ) of the chipping head (16) is inserted in the distal portion (121 ) of the drive shaft (12) and in the assembled state of the perforator (10) a partially cut securing ring (90) is arranged in the ring shaped nest (92) such that it extends into the first and second grooves (122, 162), the perimeter of the securing ring (90) being variable by elastic deformation.
Patent CA-3152552-A1 (CA)
Inventor: DOWNEY PAUL CHARLES
IPC: E04C2/24
Filed: 2022-03-17
Abstract: In an aspect a method of manufacturing an acoustic floor panel is described.  The method may include: combining a binding agent with plastic flakes; passing the plastic flakes and the binding agent to a lamination machine; applying a force to the binding agent and the plastic flakes using the lamination machine to create a plastic sheet; cutting the plastic sheet;  and adding an acoustic insulator to at least a first side of the plastic sheet.
Patent CA-3152717-A1 (CA)
Title: Tool mounting device
Inventor: HENRY JR MARK ANTHONEY
IPC: B25H5/00
Filed: 2022-03-18
Abstract: A tool mounting device may have a base having a first base flange and a second base flange extending therefrom. A tool support may be connected to the first and second base flanges where the tool support may be adapted for selective pivotal motion with respect to the first and second base flanges. The tool support may have a first arm and a second arm and the arms may be connected by an arm base. The arms may also be adapted to support a tool thereon. A biasing member may be connected between one of the base flanges and the tool support.
Patent CA-3154391-A1 (CA)
Inventor: KIRSCHBERG THORSTEN A
IPC: A61K31/501
Filed: 2020-09-11
Abstract: Provided herein are compounds, preferably thyroid hormone receptor beta (THR beta) agonist compounds, compositions thereof, and methods of their preparation, and methods of agonizing THR beta and methods for treating disorders mediated by THR beta.
Patent CA-3155020-A1 (CA)
Title: Wheelend assembly grease tool
Inventor: TREJO JIMENEZ DANIEL
IPC: B60B27/00
Filed: 2020-09-23
Abstract: A grease tool for a unitized wheelend assembly is provided. The grease tool may have a plug with a fluid conduit to place a lubrication source in fluid communication with an inner bearing and a cap with a fluid conduit to place the lubrication source in fluid communication with an outer bearing. The grease tool may include a cylindrical body having an inner bearing support and an outer bearing support. The cylindrical body has an inner rotor and disc and an outer rotor and disc where the inner rotor and the outer rotor cause the discs to move between an extended and retracted position.
Patent CA-3156732-A1 (CA)
Inventor: SEVEN KARL M
IPC: C08L67/00
Filed: 2020-11-03
Abstract: A method includes steps of (a) blending a polymeric composition, including: (i) 5 wt% to 45 wt% of a silanol-functionalized polyolefin based on a total weight of the polymeric composition; (ii) 55 wt% to 90 wt% of a polybutylene terephthalate based on a total weight of the polymeric composition having a melt flow index from 21 g/10 min. to 35 g/10 min. at 250°C and 2.16 kg; (iii) a condensation catalyst; and (iv) 0.5 wt% to 10 wt% of hydroxy terminated poly(dimethylsiloxane) based on a total weight of the polymeric composition; and (b) extruding the polymeric composition.
Patent CA-3157046-A1 (CA)
Inventor: PALMER CHARLES F
IPC: C09K23/52
Filed: 2022-04-22
Abstract: Provided is a method and mixture for treating a hydrophobic surface. The mixture comprises a wetting agent comprising; a compound of Formula 1: wherein: R and R' are independently selected from the group consisting of H, C1-24 alkyl, aryl, C1-24 alkylaryl, aryl(C1-24)alkyl, -C(=0)-R1, C(=0)-NHR1, and C(=0)-0-R1 wherein Rlis selected from the group consisting of C1-24 alkyl, aryl, 01-24 alkylaryl, C1-24 arylalkyl; A is an organic moiety derived from the group consisting of alkylene oxides having 4-12 carbon atoms and aryl epoxides having 8-12 carbon atoms; x=1-300; y=0-200; z=0-200; and with the proviso that R and R' cannot be H or ether functionality at the same time; and a compound of Formula 11: where R2 is 01-024 alkyl, aryl, alkaryl; x = 0-20; y = 0-20; z = 1 or 2 and M is H, Na, K, Ca, Mg or Li.
Patent CA-3157451-A1 (CA)
Title: Electronic vapour inhalers
Inventor: GILL MARK
IPC: A24F40/485
Filed: 2015-11-03
Abstract: A cartridge for an electronic vapour inhaler comprises a housing and an induction heating arrangement arranged to inductively heat an induction heatable element of a cartridge or capsule inserted into the housing to heat a flavour-release medium within the cartridge or capsule. A control arrangement is arranged to energize the induction heating arrangement to inductively heat the induction heatable element and thereby heat the flavour-release medium.  The control arrangement may be further arranged to recognise an inserted capsule or cartridge by detecting a characteristic of the induction heatable element and to control the operation of the induction heating arrangement based on the detected characteristic to provide a predetermined heating profile.
Patent CA-3158120-A1 (CA)
Title: Emission de relais de liaison 16 dans un creneau temporel unique de messages multiples
Inventor: CHONGOUSHIAN JOHN H
IPC: H04W72/04
Filed: 2020-10-15
Abstract: Un procédé d'émission et de réception d'une pluralité de messages de Liaison 16 sur un sous-réseau unique dans un créneau temporel unique, comprend les étapes dans lesquelles un terminal d'émission empaquette les messages de Liaison 16 en un message enveloppe à rendement amélioré (message LET enveloppe) et transmet le message LET enveloppe à un terminal de réception, après quoi le terminal récepteur désempaquette les messages de Liaison 16 provenant des messages LET enveloppe, rétablit leur forme originale et les présente à un hôte. La modification de l'hôte n'est pas nécessaire. Les messages de Liaison 16 peuvent être des messages relayés, et le terminal de transmission peut être une terminal de relais. Les messages de Liaison 16 peuvent être concaténés dans les message LET enveloppes, ou un autre algorithme d'empaquetage sans perte, tel que la compression sans perte, peut être appliqué. Les terminaux peuvent être des terminaux JTRS, les messages de Liaison 16 peuvent être des messages de 115 kbps, et le message LET enveloppe peut être un message LET de 2 Mbps.
Patent CA-3158382-A1 (CA)
Inventor: LIM HWAYEON
IPC: C12Q1/6806
Filed: 2020-09-09
Abstract: La présente invention concerne un procédé de raffinage d'acides nucléiques et, en particulier, un procédé de raffinage d'acides nucléiques comprenant : une première étape de cristallisation d'acides nucléiques au moyen d'une solution comprenant un solvant organique hydrophile ; et une seconde étape de séchage des acides nucléiques cristallisés au moyen d'air fortement humide et chaud.
Patent CA-3158647-A1 (CA)
Title: Hideaway headache rack
Inventor: CUNNINGHAM MICHAEL
IPC: B60R9/00
Filed: 2022-05-05
Abstract: A rack comprising: (a) a mounting bracket adapted to mount the rack to a cargo box of a vehicle; and (b) a rotary member in communication with the mounting bracket, wherein the rotary member rotates relative to the mounting bracket to move the rack between an extended position where the rack extends beyond a top edge of the cargo box and a stowed position where the rack in positioned within the cargo box below the top edge.
Patent CA-3159338-A1 (CA)
Title: Threat mitigation system and method
Inventor: MURPHY BRIAN P
IPC: G06F21/00
Filed: 2020-11-25
Abstract: A computer-implemented method, computer program product and computing system for: establishing connectivity with a plurality of security-relevant subsystems within a computing platform; defining a unified query on a unified platform concerning the plurality of security-relevant subsystems; denormalizing the unified query to define a subsystem-specific query for each of the plurality of security-relevant subsystems, thus defining a plurality of subsystem-specific queries; and providing the plurality of subsystem-specific queries to the plurality of security-relevant subsystems.
Patent CA-3159516-A1 (CA)
Title: Constructions de therapie genique de la microdystrophine et leurs utilisations
Inventor: QIAO CHUNPING
IPC: C07K14/47
Filed: 2020-11-27
Abstract: L'invention concerne, en partie, de nouvelles constructions géniques qui codent pour une protéine de la microdystrophine pour une utilisation en thérapie génique. Les constructions géniques de la microdystrophine et les cassettes d'expression ont été modifiées pour une thérapie améliorée quant à l'efficacité, à la puissance et à la sécurité du sujet lorsqu'elles sont exprimées par un vecteur viral dans des cellules musculaires et/ou des cellules du SNC.
Patent CA-3159650-A1 (CA)
Inventor: DONG SONGTAO
IPC: B01J29/16
Filed: 2020-10-29
Abstract: La présente invention concerne un catalyseur supporté, son procédé de préparation, et son application. Le catalyseur supporté fourni par la présente invention comprend un support et un composant actif métallique supporté sur le support ; le composant actif métallique est choisi parmi au moins l'un élément métallique du groupe VIB et d'un élément métallique du groupe VIII ; le support contient au moins l'un d'un oxyde inorganique résistant à la chaleur et d'un tamis moléculaire ; le support comprend un canal de pore traversant à l'intérieur, et le rapport de la surface de section transversale du canal de pore à la surface de section transversale du support est de 0,05-3 : 100 ; la différence R entre l'absorption d'eau du support et le volume de pore BET n'est pas inférieure à 0,2 mL/g Le catalyseur supporté fourni par la présente invention peut être utilisé comme catalyseur d'hydrogénation, et lorsque le catalyseur supporté est utilisé pour l'hydrocraquage d'huile hydrocarbonée, à la fois une activité catalytique élevée et un rendement en carburéacteur élevé peuvent être obtenus. Le catalyseur supporté fourni par la présente invention peut également être utilisé comme catalyseur de synthèse de Fischer-Tropsch, et lorsqu'Il est utilisé pour la synthèse de Fischer-Tropsch, le catalyseur présente les avantages d'une résistance élevée et d'un rendement d'activité élevé. De plus, du fait d'une résistance à l'écrasement radial élevée sans sacrifier l'activité catalytique, le catalyseur supporté fourni par la présente invention est particulièrement approprié pour être utilisé dans un réacteur à lit fixe.
Patent CA-3161629-A1 (CA)
Inventor: HANAN JAY CLARKE
IPC: B65D41/34
Filed: 2020-11-17
Abstract: An apparatus and methods are provided for a container closure that includes a tether that keeps the closure coupled with a plastic container after the closure has been unsealed to access contents within the container. The container closure comprises a closure portion coupled to a tamper evidence band by a tether bridge. The closure portion threadably engages with a finish portion of the container and seal contents in an interior of the container. The tamper evidence band remains engaged with the finish portion when the closure portion is removed from the finish portion. A multiplicity of thin connections between the tamper evidence band and the closure portion break apart when the closure portion is untightened from the finish portion. The tether bridge remains unbroken and is configured to allow the closure portion to be tilted away from the finish portion by an end-user.
Patent CA-3164932-A1 (CA)
Title: Appareil et methode pour optimiser et adapter le traitement de multiples tumeurs par des champs electriques chez des patients ayant une maladie metastatique
Inventor: TRAVERS PETER F
IPC: A61N1/40
Filed: 2020-12-14
Abstract: La présente invention concerne une méthode d'administration de champs électriques traitant les tumeurs au corps d'un patient. La présente méthode comprend le balayage du corps du patient pour identifier au moins deux zones chargées de tumeurs. Ladite méthode comprend en outre la détermination d'une relation spatiale entre les au moins deux zones chargées de tumeurs. Ladite méthode comprend en outre l'agencement d'un réseau d'éléments d'électrode isolés sur le corps du patient. Ladite méthode comprend en outre la mise en uvre d'au moins deux configurations d'amorçage de sous-réseau pour le réseau d'éléments d'électrode isolés afin de traiter les au moins deux zones chargées de tumeurs en fonction au moins en partie de la relation spatiale entre les au moins deux zones chargées de tumeurs de telle sorte que chaque configuration d'amorçage de sous-réseau traite une zone chargée de tumeurs respective. La présente invention porte en outre sur une méthode de configuration d'un appareil de champ de traitement de tumeur et sur un appareil de champ de traitement de tumeur comprenant un réseau d'éléments d'électrode isolés couplés à un dispositif de commande.
Patent CA-3166556-A1 (CA)
Title: Method and device for generating target advertorial based on deep learning
Inventor: ZHU JINGTAO
IPC: G06F40/166
Filed: 2020-06-19
Abstract: A deep learning-based target advertorial generating method and apparatus. The method comprises: receiving related information of a target object, matching several adapted target headlines from a headline library according to the related information, the headlines in the headline library being expanded from acquired headlines by means of a third generation model (S1); inputting the target headline into the first generation model to generate at least one target introduction (S2); generating at least one piece of input information that conforms to a preset structure according to the related information and a preset rule, and inputting the input information into a second generation model to generate at least one target body (S3); and assembling the target headline, the target introduction, and the target body to obtain multiple target advertorials (S4). By using deep learning and natural language processing technology, the automatic, intelligent and diversified generation of marketing advertorials can be implemented, the investment of operators is reduced, the production efficiency of marketing advertorials is improved, the problem of low handwriting efficiency is effectively avoided, and the problem of dull template generation is also avoided.
Patent CA-3170223-A1 (CA)
Title: Recipient de collecte d'echantillon
Inventor: UCHIYAMA TAKAYA
IPC: A61J3/00
Filed: 2021-03-23
Abstract: L'invention concerne un récipient de collecte d'échantillon avec lequel il est possible de réduire au minimum un changement du rapport de mélange entre un échantillon collecté et un liquide contenu, même lorsqu'une longue période de temps s'est écoulée depuis la production.?Le récipient de collecte d'échantillon selon la présente invention est un récipient de collecte d'échantillon dans lequel un échantillon est collecté, le récipient de collecte d'échantillon étant pourvu d'un corps principal de récipient comportant une ouverture, un bouchon monté sur l'ouverture, un film barrière positionné sur la surface externe du corps de récipient, et un liquide contenu dans le corps de récipient. La perméabilité à la vapeur d'eau du film barrière à 40 °C et à une humidité relative de 90 % est inférieure ou égale à 0,8 g/m2?jour.
Patent CA-3174521-A1 (CA)
Title: System and method for enforcing montonicity in a neural network architecture
Inventor: FILHO JOAO BATISTA MONTEIRO
IPC: G06N3/08
Filed: 2022-09-14
Abstract: A computer-implemented system and method for training a neural network with enforced monotonicity are disclosed. An example system includes at least one processor and memory in communication with said at least one processor, wherein the memory stores instructions for providing a data model representing a neural network for predicting an outcome based on input data, the instructions when executed at said at least one processor causes said system to: receive a feature data as input data; predict an outcome based on the input data using the neural network; compute a loss function based on the predicted outcome and an expected outcome associated with the input data, the loss function f being dependent on a monotonicity penalty fl computed based on a set of training data including the feature data and on a set of random data; and update weights of the neural network based on the loss function.
Patent CA-3174670-A1 (CA)
Title: Eradication a distance d'agents pathogenes
Inventor: NISSENBAUM ISRAEL
IPC: A61B90/70
Filed: 2021-04-29
Abstract: L'invention concerne un procédé et un dispositif permettant l'éradication à distance d'agents pathogènes comprenant une source de lumière pour émettre une lumière UV dans la plage de longueurs d'onde de destruction d'agents pathogènes, et un milieu de transmission tangible, qui est au moins initialement résistant à la dégradation par la lumière UV. Une interface optique entre la source de lumière UV et le milieu de transmission tangible est fournie grâce à quoi, la lumière UV émise est collectée à partir de la source de lumière et transmise à travers le milieu de transmission tangible, la lumière UV émise par le milieu de transmission tangible et dirigée contre un agent pathogène à proximité de ce dernier étant à un niveau de puissance suffisant pour tuer sensiblement efficacement l'agent pathogène en une période de temps raisonnable. Le dispositif est utilisé pour la désinfection de canaux de biopsie d'endoscopes et pour le traitement d'agents pathogènes chez l'homme et l'animal.