baber/WOPTO huggingface dataset:
Patent NZ-524691-A (NZ)
Title: Calcium binding proteins
Inventor: SONDEREGGER PETER
IPC: C12N5/079
Filed: 2001-09-13
Abstract: A pharmaceutical composition comprises an amino acid sequence at least 50% identical to a sequence selected from SEQ ID NO: 2, 4 and 6 and having calcium binding activity and/or the capacity to bond to the ARP2/3 complex. The polypeptides and nucleic acid encoding them can be used in the preparation of medicament fro treatment of disorders of the nervous system a cancer. Also described are transgenic non-human animals and the use of the DNA sequences for the production of antigens and antibodies and in diagnosis.
Patent NZ-525887-A (NZ)
Title: Adjuvant combination formulations
Inventor: HAGEN MICHAEL
IPC: A61K39/39
Filed: 2001-11-08
Abstract: Described is an antigenic composition comprising a selected antigen in combination with a adjuvant comprising: a) an aminoalkyl glucosamine phosphate (AGP) compound, preferably 2-[(R)-3-Tetradecanoyoxytetradecanoylamino]ethyl 2-Deoxy-4-O-phosphono-3-O[(R)-3-Tetradecanoyoxytetradecanoyl]-2-[(R)-3-Tetradecanoyoxytetradecanoylamino]-beta-D-glucopyranoside (AGP compound 529) b) granulocyte macrophage stimulating factor or interleukin-12
Patent NZ-527628-A (NZ)
Title: Refractory metal plates with uniform texture and methods of making the same
Inventor: JEPSON PETER R
IPC: C22F1/00
Filed: 2002-02-20
Abstract: A method (10) of forming sputtering target from ingots of tantalum or niobium of requisite purity by the process of cutting the ingot to short lengths (12) and pressure working (14, 22, 30, 34) the ingot along alternating essentially orthogonal work axes. Intermediate anneals (18, 26, 38) are applied as necessary to establish a uniform texture thickness-wise and area-wide throughout the target, including the center. The uniform texture is a substantially constant mix of grains with orientation (100) and (111), thereby improving sputtering performance by providing a more predictable sputter rate to control film thickness.
Patent NZ-538010-A (NZ)
Title: Method of producing reinforced, formed fabrics
Inventor: GAUTIER GERARD
IPC: B29C70/44
Filed: 2003-06-25
Abstract: A method of manufacturing a shaped reinforced cloth, comprising discontinuous reinforcing elements and a membrane which encases the reinforcing elements, wherein the cloth is produced as one piece by pressing successive portions, and, in order to form the portions of the cloth, a plurality of elements in strip form, comprising materials of the reinforcing elements and the membrane, are arranged on a preparation support, so that each element in strip form overlaps partially with the adjacent elements in strip form, and the plurality of elements in strip form is brought to and pressed portion by portion in a press provided with pressing means with an adjustable form, so as to form at the discharge from the press a cloth which comprises flat portions and/or portions shaped in three dimensions substantially according to the form which the pressing means have when the corresponding portion is pressed.
Patent NZ-540105-A (NZ)
Title: Comparing the expression level of apoptosis-specific eIF-5A with the expression levels of proliferating eIF-5A for identifying an incidence of ischemia and reducing apoptosis in mammalian tissue
Inventor: THOMPSON JOHN E
IPC: C12Q1/68
Filed: 2003-10-22
Abstract: Methods of identifying an incidence of ischemia in mammalian tissue, particularly mammalian heart tissue are described. Further, a method of reducing apoptosis in mammalian tissue, preferably heart tissue, is provided. These methods involve measuring and comparing the gene expression levels of both apoptosis-specific eIF-5A and proliferating eIF-5A and correlating an incidence of ischemia when the expression level of apoptosis-specific eIF-5A is higher than proliferating eIF-5A. In the method of reducing apoptosis in mammalian tissue, there is provided an agent that inhibits expression of apoptosis-specific eIF-5A. Preferred agents are antisense oligonucleotides to human apoptosis-specific eIF-5A. A bar chart is shown depicting the percentage of apoptosis occurring in RKO cells following transient transfection. RKO cells were transiently transfected with pHM6-LacZ, pHM6-eIF5A1, pHM6-eIF5A2, or pHM6-truncated eIF5A1. Cells transfected with pHM6-eIF5A1 showed a 25% increase in apoptosis relative to control cells transfected with pHM6-LacZ. This increase was not apparent for cells transfected with pHM6-eIF5A2 or pHM6-truncated eIF5A1.
Patent NZ-541534-A (NZ)
Title: Polyethelene glycol link glp-1 compounds
Inventor: DIMARCHI RICHARD DENNIS
IPC: A61K47/48
Filed: 2004-03-19
Abstract: Disclosed are GLP-1 compounds coupled to at least one polyethylene glycol molecule or derivative thereof, resulting in a biologically active peptide with an extended half-life and a slower clearance when compared to that of unPEGylated peptide. These PEGylated GLP-1 compounds and compositions are useful in treating diabetes, obesity, irritable bowel syndrome and other conditions that would be benefited by lowering plasma glucose, inhibiting gastric and/or intestinal motility and inhibiting gastric and/or intestinal emptying, or inhibiting food intake.
Patent NZ-543525-A (NZ)
Title: A baking Tray
Inventor: HAMBLIN RONALD GEOFFREY
IPC: A47J37/01
Filed: 2004-04-21
Abstract: A corrugated or other suitable carton board tray for baking a food product in the tray is disclosed. The tray includes a rectangular base (5), upright side walls (7), upright end walls (9), and a locking assembly (15, 17) that releasably holds together the side walls and the end walls in upright positions with the corners of the tray thereby making the corners of the baked food product produced in the tray straight and squared, and the end walls and the side walls can be folded outwards and downwards to provide access to the food product that has been baked in the tray. A blank for forming the tray is also disclosed.
Patent NZ-544703-A (NZ)
Title: Skin regeneration system
Inventor: UPTON ZEE
IPC: A61K35/12
Filed: 2004-07-28
Abstract: Provided is a mammalian cell culture medium comprising: (i) at least one insulin-like growth factor IGF-I or IGF-II, (ii) vitronectin or an integrin receptor-binding fragment thereof, (iii) an absence of serum or an amount of serum which in the absence of said at least an IGF would not support cell growth. Further provided are methods of cell culture using the said medium and use of additional insulin-like growth factor binding proteins (IGFBP) in the medium. Also provided is a method of producing a pharmaceutical composition for aerosol delivery of keratinocytes using the said culture medium.
Patent NZ-553348-A (NZ)
Title: Loan and auctioning system and method
Inventor: A COURT ALAN STANLEY JAMES
IPC: G06Q30/00
Filed: 2007-02-19
Abstract: A system enabling a borrower to conduct a reverse auction for a loan to two or more lenders includes a data communication means allowing communication with a plurality of client computers; a database; and a processing means. The processing means is adapted to communicate with the plurality of client computers via the communication means to exchange data relating to the auction; read and write the data to the database; administer the reverse auction to establish mutually agreeable loan terms between the borrower and at least one of the lenders; and rank bids for the loan lodged by lenders, during and/or at the conclusion of the auction based on a plurality of prioritised criteria specified by the borrower.
Patent NZ-553660-A (NZ)
Title: Fungicidal active ingredient combination of fluoxastrobin, fluquinconazole and triadimenol
Inventor: SUTY-HEINZE ANNE
IPC: A01N43/653
Filed: 2005-09-06
Abstract: Disclosed is an active substance combination comprising compounds of formula (I), (II) and (III), fluoxastrobin, fluquinconazole and triadimenol respectively, which is suitable for controlling phytopathogenic fungi.
Patent NZ-561458-A (NZ)
Title: Heteroaryl urea derivatives useful for inhibiting CHK1
Inventor: DIAZ FRANK
IPC: A61K31/497
Filed: 2006-03-29
Abstract: Substituted heteroaryl urea derivative compounds useful in the treatment of diseases and conditions related to DNA damage or lesions in DNA replication are disclosed. Particularly disclosed is 1-[5-bromo-4-methyl-2-S-(morpholin-2-yImethoxy)-phenyl]-3-(5-methyl-pyrazin-2-yl)-urea. Methods of making the compounds, and their use as therapeutic agents, for example, in treating cancer and other diseases characterized by defects in DNA replication, chromosome segregation, or cell division, are also disclosed.
Patent NZ-567380-A (NZ)
Title: A wave box unit being a device for generating electricity from sea shore waves
Inventor: WARDROP PETER VIVIAN
IPC: E02B9/08
Filed: 2008-04-14
Abstract: Apparatus for use in converting kinetic energy from moving water to electrical energy, the apparatus comprising a ramped water channel, a water receiving unit, a turbine, and transportation means. The apparatus is formed such that when it is in use as a shore-based installation it can be transported from the shore to a body of water via the transportation means so that the ramped water channel enters the body of water to an adjustable degree such that water contacts and moves up the ramped channel and into the water receiving unit where it drops under gravity and in so doing causes the turbine to turn to facilitate the generation of electricity.
Patent NZ-568165-A (NZ)
Title: Carton with reinforced handle using a side end reinforcement flap
Inventor: BRAND KIRSTEN LAURA
IPC: B65D5/46
Filed: 2006-11-08
Abstract: Disclosed is a carton with a reinforced handle for containing a plurality of articles. The carton comprises: a plurality of panels (30, 40) that extend at least partially around an interior of the carton; at least two end flaps (12, 22, 32) respectively foldably attached to respective panels of the plurality of panels; and a handle (11) in the closed end of the carton having a handle opening (139) for grasping and carrying the carton. The plurality of panels comprises a top panel (30), a bottom panel, a first side panel, and a second side panel (40). The end flaps are overlapped with respect to one another and thereby at least partially form a closed end of the carton. The at least two end flaps comprising at least one side end flap (22, 42) foldably attached to one of the first side panel and the second side panel, and a top end flap (32, 56) foldably attached to the top panel. The at least one side end flap comprises a main panel (70, 72) for at least partially closing the closed end of the carton and a reinforcement panel (80, 82) foldably attached to the main panel and upwardly folded relative to the main panel to at least partially overlap the main panel, the reinforcement panel cooperating with the main panel to form the handle.
Patent NZ-568461-A (NZ)
Title: Quick-fixing element that clips to either side of a bend in a rod that forms part of a tray or similar to connect the tray to a slide
Inventor: WITTGREBE ACHIM
IPC: F24C15/16
Filed: 2006-12-19
Abstract: A quick-fixing element (4) for fixing guide rails (1) to horizontally running rods (5) of a tray is disclosed. The rods are bent away at an angle in the end region from the guide rail (1), characterized in that the quick-fixing element (4) has a first clip-type retaining section (4a), which partially engages around a rod (5) in its longitudinal extent region. A second clip-type retaining section (4b) at the other end of the quick-fixing element (4) partially engages around the rod (5) in its angled end region (5a), and can be pushed in the horizontal direction onto the end region of the rod (5). The quick-fixing element (4) can be used to connect a tray in an oven to the slide attached to the oven wall.
Patent NZ-569625-A (NZ)
Title: Shear resistant rivet and saw chain with shoulder region that is softer than outer surface
Inventor: SEIGNEUR CHRIS
IPC: B23D57/00
Filed: 2006-12-05
Abstract: Disclosed is a saw chain rivet (12) which is shear resistant. The rivet includes a central flange (22) which has a circumferential outer surface with a first hardness, the flange being sized to engage a rivet hole of a first link in a saw chain. The rivet also includes a hub (24) extending from a side (26) of the flange. The rivet finally includes a shoulder region (28) defined by a junction between the flange and the hub. The shoulder region has a second hardness that is less than the first hardness. This defines strength properties of the rivet that resist shear forces at the shoulder and resist wear on the circumferential outer surface.
Patent NZ-570677-A (NZ)
Title: Method for the determination of loads on/damage to a mechanical structure
Inventor: SCHREIBER ULRICH
IPC: G01M5/00
Filed: 2007-01-31
Abstract: Disclosed is a method for determining damage to or states of a mechanical structure resulting from loads on the mechanical structure. The rotation of part of the mechanical structure, which is caused by loads on or damage to the mechanical structure, is measured using a fibre-optic rotation sensor which is connected to the part of the structure in a mechanically rigid manner. The loads on, damage to, or states of the mechanical structure are inferred from the rotation measured.
Patent NZ-573769-A (NZ)
Title: Tinting bowl
Inventor: SLOAN ASHLEY
IPC: A45D19/06
Filed: 2007-05-22
Abstract: There is disclosed a tinting bowl device (10) for use with hair treatment substances. The device includes receptacle in the form of a base bowl (12) and a plurality of receptacles in the form of liners (20) nested within the interior of base bowl. The base bowl has a lip (16) which extends around the interior to form a rim. Each receptacle that has a receptacle immediately below it is detachably fixed to that receptacle.
Patent NZ-575919-A (NZ)
Title: Tamper evident device for a container with a slider or a zipper
Inventor: BORTZ GARY
IPC: A44B19/26
Filed: 2007-07-04
Abstract: A security device 10 for a container closeable by a slide fastener having a slider 16, comprises a lower part 12 adapted for attachment to the container, means for attaching the security device 10 to the slider 16, directly or indirectly, an upper part for retaining the attaching means, receiving means 24 for receiving a frangible seal 26 and preventing retraction of the frangible seal 26 except by fracture thereof, and means to limit access to the attaching means and the receiving means. The security device 10 includes an area of weakness 30 adapted to fracture if the security device 10 is prised from the container.
Patent NZ-586779-A (NZ)
Title: Method for controlling diseases on turfgrass
Inventor: TAKAISHI MASANAO
IPC: A01N31/04
Filed: 2010-07-13
Abstract: Disclosed is a method for controlling diseases on turfgrass (such as Curvularia leaf blight, Drechslera leaf spot, Pink snow mold, Rust, Southern blight, Large patch, Fairy rings, Pythium red blight, Pythium snow blight, Crown rust, Brown ring patch, Brown stripe, Take-all, Dollar spot, Anthracnose, Brown patch, Pythium blight, Typhula snow blight and Sclerotinia Snow blight) which comprises applying to turfgrass that has been cut back an effective amount of a compound of formula (I), wherein X1 represents a methyl group, a difluoromethyl group or an ethyl group; X2 represents a methoxy group or a methyl amino group; and X3 represents a phenyl group, a 2-methylphenyl group or a 2,5-dimethylphenyl group. Of particular importance is the use of representative compounds of formula (I) such as a-methoxy-N-methyl-(2,5-dimethylphenoxymethyl)phenylacetamide and methyl 2-[2-(2-methylphenoxymethyl)phenyI]-2-difluoromethoxyacetate. Further disclosed are formulations which comprise the compounds of formula (I).
Patent NZ-588670-A (NZ)
Title: Carba-nucleoside analogs for antiviral treatment
Inventor: CHO AESOP
IPC: A61K31/41
Filed: 2009-04-22
Abstract: Disclosed is a compound comprising a 1,2,4 triazine fused to an imidazole or pyrrole ring which is bound to a tetrahydrofuran as depicted in formula (I). The substituents are as disclosed in the description. Also disclosed is a pharmaceutical composition comprising a compound of formula (I) and the use of a compound of formula (I) in the manufacture for the treatment of a viral infection caused by a virus selected from the group consisting of dengue virus, yellow fever virus, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, Kunjin virus, Murray Valley encephalitis virus, St. Louis encephalitis virus, Omsk haemorrhagic fever virus, bovine viral diarrhoea virus, Zika virus and Hepatitis C virus.
Patent NZ-595309-A (NZ)
Title: Welding head for rail welding
Inventor: VAIA DAVIDE
IPC: B23K11/00
Filed: 2009-04-16
Abstract: Disclosed is a welding head for welding the end of two sections of rail more efficiently. The welding head comprises two half -heads (10) aligned and sliding with regard to one another in a longitudinal direction. Each half -head comprises grip means (12, 13) to grasp a respective section of rail and two electrodes suitable for contact with respective sections of rail in order to carry out a flash butt weld. The head also comprises traction actuator means (20) which extend in a longitudinal direction and are connected to the two half- heads (10) to shift the two half-heads in a longitudinal direction one towards the other, the traction actuator means (20) having a stroke suitable for allowing, during a cycle of welding two sections of rail, simultaneous regulation of rail tensions. A cutting unit (30) removes or trims excess weld material at the end of the welding operation, the cutting unit being set between the half-heads and being configured to slide between and with regard to them in a longitudinal direction by its own actuator organ and configured to move independently of the two half-heads.
Patent NZ-595758-A (NZ)
Title: Thorium-227 for use in radiotherapy of soft tissue disease
Inventor: LARSEN ROY
IPC: A61K51/04
Filed: 2004-04-15
Abstract: 595758 A soft tissue targeting complex of thorium-227, wherein the thorium-227 is chelated by a derivative of 1,4,7,10-tetraazacyclodecane-l,4,7,l0-tetraacetic acid and the thorium-227 is conjugated to a targeting moiety with bioaffinity, excluding bone-seekers, liposomes and folate conjugated antibodies or antibody fragments.
Patent NZ-595833-A (NZ)
Title: Method of producing a lipolytic enzyme
Inventor: MADRID SUSAN M
IPC: A23L29/00
Filed: 2010-04-23
Abstract: Patent No. 595833 Disclosed is a method of producing a lipolytic enzyme comprising the steps of: (i) providing a transformed or transfected Trichoderma reesei cell comprising at least one heterologous nucleotide sequence encoding a lipolytic enzyme; (ii) culturing the cell at a of pH 4 to a pH of 5.5 under conditions to allow for expression of said heterologous nucleotide sequence(s) encoding said lipolytic enzyme; and (iii) isolating, purifying or concentrating the enzyme in a medium at a pH of 5.5 to a pH of 6.5.
Patent NZ-597307-A (NZ)
Title: Rejuvenating coronary artery by improving blood flow with the help of insertion of nano-balls (encapsulated nanoparticles) containing therapeutic agents by non implantable device for tissues and thereby providing in tissue release to address the required cell cycle
Inventor: DOSHI MANISH
IPC: A61M25/04
Filed: 2010-05-21
Abstract: 597307 A drug-delivering medical device for delivering a drug to a target site in a body lumen is disclosed. The drug-delivering medical device includes a balloon catheter and an inflatable balloon positioned on the balloon catheter. The inflatable balloon has a hydrophilic surface. One or more portions of the hydrophilic surface are coated with two or more nano-carriers. A nano-carrier of the two or more nano-carriers includes a drug surrounded by an encapsulating medium. As the drug is surrounded by the encapsulating medium, the surface of the nano-carrier is devoid of the drug. When the inflatable balloon is inflated upon coming in proximity to a target site in the body lumen, about 30% to 80% of the two or more nano-carriers are released from the hydrophilic surface within 15-90 seconds.
Patent NZ-598364-A (NZ)
Title: A method for regulating pneumatic air to a pneumatic actuator
Inventor: TESCHKE ULRICH
IPC: F15B9/12
Filed: 2007-08-08
Abstract: Disclosed is method for regulating pneumatic air to a pneumatic actuator (100). The method comprises the following steps: · Coupling an element (104) to the pneumatic actuator (100), wherein a first force acts of the element (104) and the pneumatic actuator (100) provides a second force on the element (104) opposite the first force; and · Providing a proportional actuator valve (110) wherein, the proportional actuator valve (110) controls the supply of air to and from the pneumatic actuator (100). The proportional actuator valve (110) comprises one or more grooves with non-uniform cross sectional areas, wherein the cross section areas. The cross sectional areas that open for air flow is determined by a change in the first force acting on the element (104).
Patent NZ-598420-A (NZ)
Title: Adjustable furniture
Inventor: ROBERTSON DALE
IPC: A47C20/08
Filed: 2010-08-18
Abstract: An article of adjustable furniture 10 having zero-wall functionality, comprises a base 16, an intermediate support 18 and a back support 20. The intermediate support 18 is guided for movement relative to the base 16 by a first guide means, and the back support 20 is guided for movement relative to both the base 16 and the intermediate support 18 by second guide means. The second guide means includes at least one guide associated with the back support 20 and at least one follower associated with the base support 16. The back support 16 is mounted for pivotal movement with respect to the intermediate support 18 about a pivot axis 74 spaced from the second guide means. The first and second guide means are arranged such that, in use, pivoting of the back support 20 relative to the intermediate support 18 causes the intermediate support 18 to move with respect to the base 16. The guide 72 of the second guide means is curvilinear and has one or more curved sections.
Patent NZ-601077-A (NZ)
Title: Use of an adrenal hormone-modifying agent
Inventor: HU QI-YING
IPC: C07D487/04
Filed: 2011-01-13
Abstract: Disclosed are 4-(6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl)-3-fluorobenzonitrile derivatives as represented formula (I), wherein n is 1 or 3; R is hydrogen or -C(O)N(Ra)(Rb) wherein Ra and Rb are independently alkyl, alkyl-aryl, each of Ra and Rb is optionally substituted by one or two alkoxy substituents; R1, R2, and R3, are selected independently hydrogen, halogen, cyano and aryl, said aryl is optionally substituted one or two substituents selected from halogen, with the proviso that no more than one of R1, R2, and R3 is hydrogen; and R4 and R5 are hydrogen; or a pharmaceutically acceptable salt thereof. In particular the use of a compound of formula (I) as defined above for the preparation of a pharmaceutical composition for the treatment of Cushing’s syndrome, Cushing’s disease or hypercortisolemia in a subject is also disclosed. Important compounds of formula (I) include 4’-fluoro-6-(6,7,8,9-tetrahydro-5H-imidazo[1,5-a]azepin-5-yl} biphenyl-3-carbonitrile, 3-bromo-4-(6,7,8,9-tetrahydro-5H-imidazo[1,5-a]azepin-5-yl)benzonitrile, 5-(2-chloro-4-cyanophenyl)-N-(4-methoxybenzyl)-N-methyl-6,7-dihydro-5H-pyrrolo[1,2-c]imidazole-5-carboxamide, 5-(4-cyano-2-methoxyphenyl)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazole-5-carboxylic acid (4-fluorobenzyl)methylamide, 4-(6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl)-3-fluorobenzonitrile, 5-(3-fluoro-4-methoxyphenyl)-6,7-dihydro-5H-pyrrolo[1,2 -c]imidazole, 5-(2-chloro-4-cyanophenyl)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazole-5-carboxylic acid 4-fluorobenzyl ester, 5-(2-bromo-4-fluorophenyl)-6,7,8,9-tetrahydro-5H-imidazo[1,5-a]azepine, 2-bromo-4-(6,7,8,9-tetrahydro-5H-imidazo[1,5-a]azepin-5-yl)benzonitrile, 3-pyridin-3-yl-4-(6,7,8,9-tetrahydro-5H-imidazo[1,5-a]azepin-5-yl} benzonitrile, and 3-chloro-4-(6,7,8,9-tetrahydro-5H-imidazo[1,5-a]azepin-5-yl)benzonitrile. The preferred compound of formula (I) which is disclosed is 4-[(5R)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl]-3-fluorobenzonitrile.