baber/WOPTO huggingface dataset:
Patent AU-575871-B2 (AU)
Title: Milbemycin derivatives
Inventor: GEHRET JEAN-CLAUDE
IPC: A61P33/00
Filed: 1984-11-01
Granted: 1988-08-11
Abstract: Milbemycin derivatives of the formula I    <IMAGE>  (I)  wherein A has the structure   <IMAGE>  or the structure   <IMAGE>  X is either -CH(OR1)- or -CO-, R1 is hydrogen, a silyl group or an acyl group, and R2 is methyl, ethyl, isopropyl or sec-butyl, can be prepared by singulett oxygen oxidation of the milbemycin derivatives of the formula II herein, wherein X and R2 have the above meanings, and subsequent reduction of the 15- and 14-peroxides obtained as intermediates. Compounds of the formula I can be prepared as such or in the form of compositions for controlling endo- and ectoparasites, in particular nematodes which are parasites of animals.
Patent AU-616018-B2 (AU)
Title: Compact lance with apparatus to prevent twisting of the lance
Inventor: BAYER REINHARDT
IPC: C21C5/46
Filed: 1989-06-16
Granted: 1991-10-17
Abstract: Combustion-tube holders provided in particular for compact lances can be designed to be compact and reliable, in particular in combustion tubes having small diameters, by a bush being provided between the grippers and sealing sleeve. This bush is axially displaceable inside the inner bore of the handle but is secured in the radial direction, in which arrangement, in particular in this secured position, it has an effect on the grippers, i.e. it also locks the same. This safety device against rotation is formed in particular by an elongated hole in the bush and a radial bore in the handle having an inserted shank screw. Advantageous coupling and securing of the combustion tube inside the combustion-tube holder is thus effected by turning the shank screw down onto the outer circumference of the combustion tube. Furthermore, a particularly reliable gas-return and slag-return preventer and a quick-acting valve designed to permit ease of flow are provided in the handle. The quick-acting valve is actuated via an operating lever of ergonomically advantageous design. 
<??>Figure 1 is provided for the publication. 
<IMAGE>
Patent AU-665628-B2 (AU)
Title: Cosmetic composition
Inventor: GUERRERO ANGEL AUGUSTO
IPC: A61K8/30
Filed: 1993-04-13
Granted: 1996-01-11
Abstract: A cosmetic composition is provided that includes an emulsifying copolymer formed from a major portion of a monoolefinically unsaturated carboxylic monomer and a minor portion of a long-chain acrylate or methacrylate ester monomer, a co-surfactant which is an anionic sulphosuccinate and a pharmaceutically acceptable vehicle. The preferred composition is in the form of a clear gel.
Patent AU-566979-B2 (AU)
Title: 2-alkoxyamino sulfonyl-benzene sulfonyl urea derivatives
Inventor: SHIOKAWA KOZO
IPC: A01N51/00
Filed: 1985-01-31
Granted: 1987-11-05
Abstract: Novel herbicides are produced by the novel reaction   <IMAGE> <IMAGE>  +TR  <IMAGE>  in which R1, R2 and R3 each independently is lower alkyl of 1 to 4 carbon atoms, and M is an alkali metal atom.
Patent AU-667353-B2 (AU)
Title: Stirling engine with heat exchanger
Inventor: WEBER ECKHART
IPC: F02G1/055
Filed: 1993-05-03
Granted: 1996-03-21
Abstract: A Stirling engine in which a displacer plate 5 can be moved backwards and forwards between two housing plates 1, 2, the said displacer plate being without sliding friction relative to the ends 10 of the housing along the circumference, is known. It is desirable here for the Stirling engine to be designed for larger output ranges with a reduced outlay on construction by making the housing plates and the displacer plate as large as possible, taking into consideration the resistance to pressure of the housing. This is achieved by virtue of the fact that the two housing plates 1, 2 are held at a distance from one another by struts 3 arranged in a distributed manner, the struts extending at right angles to the displacer plate 5 and passing through the latter, and by virtue of the fact that the displacer plate 5 is guided along its end edges relative to the ends 10 of the housing by linear rolling diaphragms 9. The housing plates are reinforced over the surface area by the struts and the displacer plate is guided exactly parallel with regard to the struts by the rolling diaphragms. <IMAGE>
Patent AU-761468-B2 (AU)
Title: Highly conductive molding compounds and fuel cell bipolar plates comprising these compounds
Inventor: BUTLER KURT I
IPC: H01M8/02
Filed: 2000-03-17
Granted: 2003-06-05
Abstract: A conductive polymer is disclosed which is suitable for use in applications which require corrosion resistance including resistance to corrosion when subjected to acidic flow at temperature ranging from -40 to 140 degrees Fahrenheit and which can be molded into highly intricate and thin specimens which exhibit consistent conductivity, sufficient strength and flexibility, and appropriate surface characteristics. In particular the invention involves molding unsaturated prepolymer resin composition which have high loadings of conductive fillers. Further to enable the necessary characteristics, the compositions include rheological modifiers such as Group II oxides and hydroxides; carbodiamides; aziridines; polyisocyanates; polytetrafluoroethylene (PTFE); perfluoropolyether (PFPE), and polyethylene. Ostensibly, these modifiers act to alter the apparent molecular weight and three dimensional prepolymer network structures correcting rheological deficiencies which otherwise lead to excessive resin particulate separation during the molding process and large variances in bulk conductivity across the plate surface. The composition is disclosed for use in electrochemical cells, such as fuel cells.
Patent AU-676480-B2 (AU)
Title: Homocysteine assay
Inventor: SUNDREHAGEN ERLING
IPC: G01N33/543
Filed: 1993-01-22
Granted: 1997-03-13
Abstract: There is provided a method for assaying homocysteine in a sample, e.g. blood, plasma or urine, which comprises the steps of contacting said sample with a homocysteine converting enzyme other than SAH-hydrolase and at least one substrate for said enzyme other than homocysteine, and without chromatographic separation assessing a non-labelled analyte selected from a homocysteine co-substrate and the homocysteine conversion products of the enzymic conversion of homocysteine by said enzyme.
Patent AU-628877-B2 (AU)
Title: Process for coating metal substrates with a primer powder and with a surface coating applied by dipping, powder primer compositions employed and composite materials obtained
Inventor: DUTHEIL JEAN-YVES
IPC: B05D7/24
Filed: 1989-11-02
Granted: 1992-09-24
Abstract: The present invention relates to the field of coatings of metal substrates applied by dipping. It relates to a method of coating a metal substrate using a surface coat applied by dipping after coating of said substrate with a powder primer. It also relates to powder compositions which can be used as adhesion primer, as well as to composite materials: metal substrates/adhesion primer/surface coat.
Patent AU-632770-B2 (AU)
Title: Solid encapsulated medicament and process and apparatus for preparing same
IPC: A61K9/26
Filed: 1989-11-15
Granted: 1993-01-14
Abstract: The present invention relates to the preparation of encapsulated products containing a solid dosage form prepared with up to 35% of an edible matrix material. The composition may be introduced into the capsule by injection molding or extrusion, and the resulting capsule products exhibit the favorable texture of a capsule in conjunction with the hardness, shelf stability and security of the solid formulation. The composition of the present invention may be prepared and used as a direct tableting granulation as well as the filler or core for the capsule product. A method and corresponding apparatus are likewise disclosed and contemplated herein.
Patent AU-605702-B2 (AU)
Title: Derivatives of 5-hydroxy and 5-methoxy 2-amino-pyrimidines as inhibitors of interleukin-1 production
Inventor: WALKER FREDERICK JUDSON
IPC: A61K31/505
Filed: 1989-12-12
Granted: 1991-01-17
Abstract: This invention relates to the use of certain derivatives of 5-hydroxy and 5-methoxy 2-amino-pyrimidines of the formula <CHEM> and the pharmaceutically-acceptable salts thereof, wherein R<1> is H or CH3; R<2> is CH3; R<3> is (C3-C15) straight chain alkyl or (C7-C20)phenylalkyl which may be substituted in the phenyl by one or two fluoro or chloro substituents; and R<4> is H or CH3 to inhibit interleukin-1 production in a mammal. This invention also relates to the use of such compounds for treating interleukin-1 mediated disorders and dysfunctions such as bone and connective tissue metabolism disorders and immune dysfunction in a mammal. The methods of this invention comprise administering an interleukin-1 production inhibiting amount of the compounds and salts of this invention to such a mammal.
Patent AU-579427-B2 (AU)
Title: Signal to noise ratio enhancement using baseband signals in an fm television system
Inventor: MOBLEY JOSEPH G
IPC: H04N5/44
Filed: 1985-10-25
Granted: 1988-11-24
Abstract: In an FM television signal angle modulated with luminance and chrominance information, there exists a high degree of correlation between picture elements occurring one line period apart. In an effort to steer the pass band of a tunable bandpass filter to the instantaneous frequency of the incoming television signal, a steering signal is developed which utilizes this high degree of correlation. For NTSC systems, luminance information is delayed by one-line period (63.5 us in the U.S.A.) and combined with suitable delayed chrominance information to form the filter's steering signal. For MAC systems, one-line delayed luminance and two-line delayed chrominance information are alternately applied to the filter as its steering signal. By steering the pass band of the filter to the incoming signal, maximum signal will be captured with minimum noise, enhancing the signal-to-noise ratio of a color television system.
Patent AU-577648-B2 (AU)
Title: Method for improving the filterability of a polysaccharide containing microbial broth
Inventor: DROZD JAN WILLIAM
IPC: C12P1/00
Filed: 1985-12-12
Granted: 1988-09-29
Abstract: Method of improving the filterability of a microbial broth containing microbial cell matter resulting from the breaking down of cells, which comprises contacting that broth with one or more enzymes having nuclease activity; use of the method for improving the flow of a microbial polysaccharide containing fluid displacement solution which is applied in enhanced oil recovery.
Patent AU-718327-B2 (AU)
Title: Variants of vascular endothelial cell growth factor having antagonistic properties
Inventor: KEYT BRUCE A
IPC: A61P17/06
Filed: 1997-10-10
Granted: 2000-04-13
Abstract: The present invention involves the preparation of vascular endothelial growth factor (VEGF) antagonist molecules comprising variant VEGF polypeptides which are capable of binding to and occupying cell surface VEGF receptors without inducing a VEGF response, thereby antagonizing the biological activity of the native VEGF protein. Specifically, the variant VEGF polypeptides of the present invention comprise modifications of at least one cysteine residue in the native VEGF sequence, thereby inhibiting the ability of the variant polypeptide to dimerize through the formation of disulfide bonds. The present invention is further directed to methods for preparing such variant VEGF antagonists and to methods, compositions and assays utilizing such variants for producing pharmaceutically active materials having therapeutic and pharmacologic properties that differ from the native VEGF protein.
Patent AU-723138-B2 (AU)
Title: Luminal endoprosthesis for ramification
Inventor: FRID NOUREDDINE
IPC: A61F2/856
Filed: 1998-01-16
Granted: 2000-08-17
Abstract: A luminal endoprosthesis for ramification of anatomical conduits in mammals, especially humans, and to a method for manufacturing this endoprosthesis. The latter includes at least one radially compressible and extendable tubular structure and includes at least one base element 12 with a continuous multifilament structure delimiting a longitudinal cavity 14 open at its two ends 16, 18. This at least one base element 12 includes two flexible segments 20, 22 extending one in a continuation of the other, substantially along the same axis in the absence of stress, and at least one lumen 24 opening into the cavity 14.
Patent AU-767840-B2 (AU)
Title: Energy transfer dyes
Inventor: KUMAR SHIV
IPC: C12Q1/6818
Filed: 1999-08-30
Granted: 2003-11-27
Abstract: Energy transfer dyes, their preparation, and their use as labels in biological systems is disclosed. The dyes are preferably in the form of cassettes which enable their attachment to a variety of biological materials. The dyes and the reagents that can be made from them offer a wide variety of fluorescent labels with large Stokes' shifts enabling their use in a variety of fluorescence applications over a wide range of the visible spectrum. The energy transfer dyes may be of the formula:<BR> <BR> D<SB>1</SB>- L<SB>1</SB>-A-L<SB>2</SB>- D<SB>2</SB><BR> <BR> wherein<BR> <SL> <LI>D<SB>1</SB> is a first dye moiety suitable as an acceptor or donor in an energy transfer arrangement; <LI>D<SB>2</SB> is a second dye moiety suitable as a donor or acceptor in an energy transfer arrangement with the first dye; </SL> ```A comprises 5-20 linked atoms, wherein the linked atoms contain at least one aryl or heteroaryl group and wherein the atoms are independently selected from the group consisting of carbon, nitrogen, sulfur, oxygen, phosphorus;<BR> ```L<SB>1</SB> and L<SB>2</SB> comprise a group of linked atoms and L<SB>2</SB> is adapted for attaching to a biological target. The following are specifically claimed 5-FAM-Phe-5-REG-11-ddUTP, 5-FAM-Phe-5-REG-11-ddCTP, 5-FAM-Phe-5-REG-11-ddATP, 5-FAM-Phe-5-REG-11-ddGTP, 5-FAM-Phe-5-ROX-11-ddCTP, 5-FAM-Phe-5-ROX-11-ddUTP, 5-FAM-Phe-5-ROX-11-ddATP, 5-FAM-Phe-5-ROX-11-ddGTP, 5-FAM-Phe-5-TAMARA-11-ddGTP, 5-FAM-Phe-5-TAMARA-11-ddATP, 5-FAM-Phe-5-TAMARA-11-ddCTP, 5-FAM-Phe-5-TAMARA-11-ddUTP, 5-FAM-Phe-5-R110-11-ddATP, 5-FAM-Phe-5-R110-11-ddUTP, 5-FAM-Phe-5-R110-11-ddGTP, and 5-FAM-Phe-5-R110-11-ddCTP. An energy transfer cassette may be of the formula: <EMI ID=1.1 HE=19 WI=43 LX=1009 LY=1917 TI=CF> <PC>```wherein F<SP>1</SP> is a first dye suitable as an acceptor or donor in an energy transfer arrangement;<BR> ```F<SP>2</SP> is a second dye that is suitable as a donor or acceptor in an energy transfer arrangement with the first dye;<BR> ```B is one or more alkyl groups containing from 1 to 30 atoms, wherein said atoms comprise one or more -NH-, -O-, -CH=CH-, -C  I  C- and phenylenyl groups, and wherein said atoms are selected from the group consisting of C<SB>1-4</SB> linear or branched alkyl, hydroxyl, halo, or phenyl;<BR> ```M<SP>3</SP> comprises hydrogen or a reactive or functional group adapted for attaching the energy transfer dye to a target material; and<BR> ```D comprises an atom or group adapted for attaching F<SP>2</SP> to the linker group B.
Patent AU-773371-B2 (AU)
Title: Dual isolation valve with rectangular flow passageways
Inventor: RAINWATER EDWARD L
IPC: F16K27/06
Filed: 1999-08-31
Granted: 2004-05-20
Abstract: A dual isolation valve comprises: a valve body with opposed inlet and outlet ports that defines an inner cavity; a first valve member; and a second valve member. The first valve member (preferably a plug) has a narrower first end and a wider second end and is rotatably mounted within the valve body cavity for rotation about a first axis of rotation substantially perpendicular to the flow axis defined by the inlet and outlet ports. The first valve member includes a substantially rectangular flow passage. The first end of the first valve member extends away from the second end along the first axis of rotation in a first direction, and the first valve member is rotatable between an open position, in which the flow passage is oriented to be generally aligned with and located on the flow axis to enable fluid entering the inlet port to pass through the flow passage, and a closed position, in which the flow passage is oriented to be generally perpendicular to the flow axis to prevent fluid entering the inlet port from passing through the flow passage. The second valve member also has a narrower first end and a wider second end and is rotatably mounted within the valve body cavity for rotation about a second axis of rotation substantially perpendicular to the flow axis. The first end of the second valve member extends away from the second end along the second axis of rotation in a second direction opposite the first direction (such that the first and second valve members are oriented in opposed directions). The second valve member, which also has a substantially rectangular flow passage, is rotatable between an open position, in which the flow passage is oriented to be generally aligned with and located on the flow axis to enable fluid exiting the first valve member to pass through the flow passage to the outlet port, and a closed position, in which the flow passage is oriented to be generally perpendicular to the flow axis to prevent fluid exiting the first valve member from passing through the flow passage to the outlet port. In this configuration, the flow of fluid through valve can be disturbed less than with prior art dual isolation valves while permitting extensive flow through the valve.
Patent AU-684737-B2 (AU)
Title: Use of sterile mesomorphic phases in food products
Inventor: HEERTJE ISAAC
IPC: A23L27/60
Filed: 1993-12-09
Granted: 1998-01-08
Abstract: A process for the preparation of a sterile mesomorphic phase of surfactants, comprising the sequential steps of: (a) preparing a premix comprising surfactants and water at a temperature above the Krafft temperature of the surfactant; (b) sterilising the premix at a temperature above 115  DEG C; and (c) cooling the premix to below the Krafft temperature of the surfactants, said process also comprising (before, during or after step c) the aseptically filling into a suitable package.
Patent AU-626704-B2 (AU)
Title: Improved aqueous cleaner/degreaser compositions
Inventor: VANEENAM DONALD N
IPC: C11D1/22
Filed: 1990-06-12
Granted: 1992-08-06
Abstract: Improved stable, aqueous cleaner/degreaser compositions formulated in the form of totally water soluble solutions comprise: (a) at least one sparingly water soluble organic solvent characterized by: (i) having a watersolubility in the range of approximately 0.2 to approximately 6 weight percent; (ii) not being a hydrocarbon or halocarbon; (iii) having one or more similar or dissimilar oxygen, nitrogen, sulfur or phosphorous containing functional groups; (iv) being a solvent for hydrophobic soilants; and (v) being present in an amount exceeding its aqueous solubility; (b) a solubilizing additive consisting of from approximately 0.1 to approximately 100 weight percent of a surfactant and from 0 to approximately 99.9 weight percent of a coupler, the solubilizing additive being present in an amount not exceeding approximately tenfold that required to completely solubilize the organic solvent; and (c) water. Such compositions exhibit markedly superior cleaning/degreasing efficacy over that achievable with compositions containing infinitely water soluble organic solvents such as butyl cellosolve.
Patent AU-682852-B2 (AU)
Title: C10 taxane derivatives and pharmaceutical compositions
Inventor: HOLTON ROBERT A
IPC: C07C323/50
Filed: 1994-01-14
Granted: 1997-10-23
Abstract: Taxane derivatives substituted on the C10 position with novel substituents are disclosed. The novel compounds have utility as antileukemia and antitumor agents.
Patent AU-673908-B2 (AU)
Title: A process for the preparation of 1,3,5-triazine carbamates from amino-1,3,5-triazines and organic carbonates
Inventor: FLOOD LAWRENCE A
IPC: C07C251/70
Filed: 1994-05-13
Granted: 1996-11-28
Abstract: Provided is a process for preparing an at least bis-carbamate functional 1,3,5-triazine by contacting an at least diamino-1,3,5-triazine, an acyclic organic carbonate and a base, as well as certain novel compositions producible thereby. Also provided are substantially halogen contamination free crosslinker compositions comprising the products obtainable by the process, and curable compositions based upon these crosslinkers.
Patent AU-536650-B2 (AU)
Title: Refractory element
Inventor: GROSJEAN JEAN-CLAUDE
IPC: C21C7/072
Filed: 1980-12-02
Granted: 1984-05-17
Abstract: A device for blowing gas under pressure into a bath of liquid metal comprises a mass of refractory material which is porous at least at an inner portion thereof and placed into a metallic container constituted by an outer metallic envelope closed at one of the ends thereof by a bottom member through a central portion of which a conduit extends for feeding a gas under pressure to the porous inner portion of the mass. A deflector is provided fluid-tightly connected to the bottom inwardly of the envelope in which the wall of the deflector extends parallel to that of the envelope but short of the length of the latter. This permits, on the one hand, to avoid penetration of liquid metal between the envelope and the mass of refractory material to a point where it would block the gas feeding conduit and, on the other hand, to canalize the gas through the porous portion of the mass. The present invention relates likewise to a method of making the above device.
Patent AU-634125-B2 (AU)
Title: (diethylamino-n-oxide) ethylamino-dihydroxyanthracene-9, 10-dione derivatives
IPC: A61K31/135
Filed: 1990-10-12
Granted: 1993-02-11
Abstract: PCT No. PCT/GB90/01574 Sec. 371 Date Apr. 10, 1991 Sec. 102(e) Date Apr. 10, 1991 PCT Filed Oct. 12, 1990.Compounds of formula (I) <IMAGE> (I)  in which R1, R2, R3 and R4 are each separately selected from hydrogen, X, NH-A-NHR and NH-A-N(O)R'R'' wherein X is hydroxy, halogeno, amino, C1-4 alkoxy or C2-8 alkanoyloxy, A is a C2-4 alkylene group with a chain length between NH and NHR or N(O)R'R'' of at least 2 carbon atoms and R, R' and R'' are each separately selected from C1-4 alkyl groups and C2-4 hydroxyalkyl and C2-4 dihydroxyalkyl groups in which the carbon atom attached to the nitrogen atom does not carry a hydroxy group and no carbon atom is substituted by two hydroxy groups, or R' and R'' together are a C2-6 alkylene group which with the nitrogen atom to which R'' and R'' are attached forms a heterocyclic group having 3 to 7 atoms in the ring, but with the proviso that at least one of R1 to R4 is a group NH-A-N(O)R'R'', and physiologically acceptable salts thereof are of value in the treatment of cancer.
Patent AU-733898-B2 (AU)
Title: Immunotoxins and methods of inducing immune tolerance
Inventor: NEVILLE DAVID M
IPC: A61K47/48
Filed: 1998-03-05
Granted: 2001-05-31
Abstract: Provided are novel DT- and ETA-based immunotoxins and a method of treating an immune system disorder not involving T cell proliferation, comprising administering to the animal an immunotoxin comprising a mutant diphtheria toxin moiety linked to an antibody moiety which routes by the anti-CD3 pathway, or derivatives thereof under conditions such that the disorder is treated. Thus, the present method can treat graft-versus-host disease. Also provided is a method of inhibiting a rejection response by inducing immune tolerance in a recipient to a foreign mammalian donor tissue or cells, comprising the steps of: a) exposing the recipient to an immunotoxin so as to reduce the recipients's peripheral blood T-cell lymphocyte population by at least 80%, wherein the immunotoxin is anti-CD3 antibody linked to a diphtheria protein toxin, wherein the protein has a binding site mutation; and b) transplanting the donor cells into the recipient, whereby a rejection response by the recipient to the donor organ cell is inhibited, and the host is tolerized to the donor cell.