baber/WOPTO huggingface dataset:
Patent CA-3101131-A1 (CA)
Title: Compositions and methods for preventing and treating coronavirus infection - sars­cov-2 vaccines
Inventor: LANGEDIJK JOHANNES PETRUS MARIA
IPC: C12N15/85
Filed: 2020-11-28
Abstract: COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING CORONAVIRUS    Abstract The invention relates to immunogenic compositions and vaccines containing a coronavirus (e.g., Wuhan coronavirus (2019-nCoV; also referred to as SARS-CoV-2)) protein or a polynucleotide encoding a coronavirus (e.g., Wuhan coronavirus (2019-nCoV;  SARS-CoV-2)) protein and uses thereof. The invention also provides methods of treating and/or preventing a coronavirus (e.g., Wuhan coronavirus (2019-nCoV; SARS-CoV-2)) infection by administering an immunogenic composition or vaccine to a subject (e.g., a human). The invention also provides methods of detecting and/or monitoring a protective anti-coronavirus (e.g., Wuhan coronavirus (2019-nCoV; SARS-CoV-2)) antibody response (e.g., anti-coronavirus antibody response, e.g., anti-2019-nCoV antibody response, e.g., anti-Spike antibody response, e.g., anti-Spike neutralizing antibody response). The present invention relates to isolated nucleic and/or recombinant nucleic acid encoding a coronavirus S protein, in particular a SARS-CoV-2 S protein, and to the coronavirus S  proteins, as well as to the use of the nucleic acids and/or proteins thereof in vaccines. <1093966> Date Recue/Date Received 2020-11-28
Patent CA-3101186-A1 (CA)
Inventor: FLORCZAK KELD
IPC: A01K11/00
Filed: 2019-05-20
Abstract: An animal ear tag (100) contains control circuitry (230) for generating data relating to an animal (A) to which the animal ear tag (100) is attached. An antenna (240) in the tag (100) emits a wireless signal including the data, and an energy storage (130) provides electric energy to the control circuitry (230) and the antenna (240). The energy storage (130) is arranged in a first part (P1) of the animal ear tag (100) and the antenna (240) is arranged in a second part (P2) of the animal ear tag (100). When attached to the animal (A), the first and second parts (P1; P2) are interconnected via a shaft member (210) inserted through an ear (E) of the animal (A) in such a manner that the first part (P1) is located on a first side (S1) of the ear (E) and the second part (P2) is located on a second side (S2) of the ear (E). When the first and second parts (P1; P2) are interconnected, the energy storage (130) is located off-centered (dOFF) from a symmetry axis (C-S) of the shaft member (210). As a result, the tag (100) becomes relatively fixed in a well-defined orientation.
Patent CA-3101251-A1 (CA)
Title: Bleomycine pour imiter l'effet de rayonnements ionisants sur des cellules t
Inventor: TORRO ADELINE
IPC: G01N33/68
Filed: 2019-06-07
Abstract: La présente invention concerne un procédé pour imiter les effets de rayonnements ionisants sur des cellules, les cellules étant mises en contact avec de la bléomycine.
Patent CA-3102162-A1 (CA)
Title: Phenolic-based metamaterials and methods of forming phenolic-based metamaterials
Inventor: ALBERTELLI ALDINO
IPC: C08K7/20
Filed: 2019-05-30
Abstract: The present invention relates tophenolic-based metamaterials and methods for preparing phenolic-based materials. The present invention also relates to composites formed from phenolic-based metamaterials. More specifically, the present invention is concerned with phenolic materials formed by heating phenolic resin mixtures.
Patent CA-3105994-A1 (CA)
Inventor: LAKINS MATTHEW
IPC: A61K39/395
Filed: 2019-07-12
Abstract: The invention relates to specific binding members that bind CD137. The specific binding members comprise a CD137 antigen-binding site located in a constant domain of the specific binding member and find application in the treatment of cancer and infectious diseases, for example.
Patent CA-3107021-A1 (CA)
Inventor: PALLISTER DAVID M
IPC: H01M8/04029
Filed: 2019-07-24
Abstract: The disclosed technology relates to a heat transfer system and heat transfer method employing a heat transfer fluid. In particular, the technology relates to an aqueous heat transfer fluid with low electrical conductivity, low flammability, and low freeze point that provides excellent peak temperature reduction in a heat transfer system, such as that for cooling battery modules in electric vehicles.
Patent CA-3110311-A1 (CA)
Inventor: COURNIA ZOE
IPC: C07D213/81
Filed: 2019-08-23
Abstract: The invention relates to novel compounds of formula (I)                                                                                        a tautomer, hydrate, solvate, or a pharmaceutically acceptable salt thereof, wherein L is independently H or OH; X is independently N or C; Y is independently H or =0; Z is independently S or NH; and Ri is independently mono- or polycyclic aryl, heteroaryl, or cycloalkyl. These compounds are useful in medicine, specifically in treating or preventing cancerous diseases in a mammal, and to pharmaceutical compositions comprising such compounds, optionally together with other pharmaceutically active compounds, as well as pharmaceutical formulations comprising such compounds or pharmaceutical compositions. The invention further discloses methods of manufacturing such compounds.
Patent CA-3111512-A1 (CA)
Title: Procedes et compositions pour induire une plasticite neurale
Inventor: SILVER JERRY
IPC: A61K47/62
Filed: 2019-08-29
Abstract: L'invention concerne un procédé de promotion de la plasticité compensatoire de cellules neurales épargnées après une lésion neuronale, comprenant la mise en contact des cellules neurales épargnées avec une quantité efficace d'un agent thérapeutique comprenant un peptide thérapeutique, le peptide thérapeutique comprenant une séquence d'acides aminés ayant au moins 70 % d'identité avec SEQ ID NO:32.
Patent CA-3112436-A1 (CA)
Inventor: PUTTICK DEBBIE
IPC: A01H5/10
Filed: 2019-02-15
Abstract: Provided are variants of the Camelina sativa acetohydroxyacid synthase (AHAS) enzyme that provide camelina plants with increased tolerance to Group 2 herbicides, such as for example thifensulfuron-methyl. Also provided are polynucleotides encoding the variant AHAS enzymes, and plants, plant parts, seeds and cells containing the variant polynucleotides and polypeptides. Uses of the plants and seeds are also disclosed, such as for producing progeny, for growing plants in a field, or for introgression of the herbicide resistance trait into another camelina variety.
Patent CA-3115408-A1 (CA)
Inventor: KOGA JEFFREY
IPC: B65F3/00
Filed: 2021-04-16
Abstract: A refuse vehicle comprising a chassis, a body assembly coupled to the chassis, the body assembly defining a refuse compaitnient, one or more sensors coupled to the body and configured to provide data relating to the presence of an obstacle within an area near the refuse vehicle, a controller configured to receive the data from the one or more sensors, determine, using an obstacle detector and the data, the presence of an obstacle within the area and initiate a control action, wherein the control action includes at least one of controlling the movement of the refuse vehicle, controlling the movement of a lift assembly attached to the body assembly, or generating an alert.
Patent CA-3117911-A1 (CA)
Title: Antibacterial agent against enterobacterium which contains equol as active ingredient
Inventor: TATEDA KAZUHIRO
IPC: A61P35/00
Filed: 2019-10-29
Abstract: Provided is an antibacterial drug against an enterobacterium that can cause an infection in a human body, such as Clostridioides difficile. An antibacterial agent against an enterobacterium, which contains equol as an active ingredient.
Patent CA-3123887-A1 (CA)
Inventor: JEN FREDA E -C
IPC: A61K39/095
Filed: 2019-12-20
Abstract: This invention relates generally to polynucleotides, polypeptides, compositions, methods and uses for eliciting an immune response to Neisseria, methods for immunizing a subject against a Neisseria infection, and methods for preventing and/or treating a Neisseria infection in a subject. More particularly, the invention relates to antigenic Neisseria polypeptides and encoding polynucleotides, and related uses and methods, including use for preparing compositions and medicaments for eliciting an immune response to Neisseria, for immunizing a subject against a Neisseria infection, and for preventing and/or treating a Neisseria infection in a subject. The invention also relates to methods for producing therapeutic anti-Neisseria antigen-binding molecules, and therapeutic uses of those antigen-binding molecules.
Patent CA-3126637-A1 (CA)
Title: System and method for enabling one or more transfer features associated with a real-time transfer protocol
Inventor: DUNJIC MILOS
IPC: G06F16/90
Filed: 2021-08-03
Abstract: A server computer system, comprises a processor; a communications module coupled to the processor; and a memory coupled to the processor, the memory storing instructions that, when executed, configure the processor to receive, via the communications module and from a client device, a signal including a request to configure a transfer of data to a particular data record; determine that the particular data record is associated with a third party server; obtain a trust score associated with the particular data record; determine that the trust score satisfies trust criteria; and responsive to determining that the trust score satisfies trust criteria, enable one or more transfer features associated with a real-time transfer protocol.
Patent CA-3128498-A1 (CA)
Inventor: MELLGARD BJORN
IPC: C07K14/745
Filed: 2020-01-31
Abstract: La présente invention concerne un procédé pour le traitement prophylactique d'un saignement spontané chez un sujet atteint d'une maladie De von Willebrand Sévère comprenant L'administration d'une quantité thérapeutique de facteur de von Willebrand recombinant (rVWF) au sujet.
Patent CA-3135386-A1 (CA)
Inventor: BEHR CONNOR DAVID
IPC: C12P21/00
Filed: 2020-03-31
Abstract: Disclosed herein are eukaryotic host systems for producing recombinant proteins, eukaryotic hosts modified to produce recombinant proteins, and methods of producing recombinant proteins using the same. In certain embodiments, the eukaryotic host system is a plasmodium of the class Myxogastria, such as Physarum polycephalum, modified to produce one or more recombinant proteins, such as human insulin. In certain embodiments, a method of protein production includes collecting one or more recombinant proteins produced by Physarum polycephalum while in a form of multinucleate plasmodia.
Patent CA-3135512-A1 (CA)
Inventor: CHEN BANGCHI
IPC: C07C69/612
Filed: 2019-04-01
Abstract: La présente invention concerne un procédé de préparation d'un dérivé d'acide 2-arylmalonique, un intermédiaire et une utilisation associée. Le procédé selon l'invention utilise un composé cyclohexadiène en tant que matière première, et réalise de manière séquentielle une réaction d'isomérisation, une réaction d'halogénation en présence d'un agent d'halogénation et une réaction d'aromatisation de déshydrohalogénation à une certaine température pour obtenir un dérivé d'acide 2-arylmalonique. Par comparaison avec l'état de la technique, l'invention présente les caractéristiques et avantages remarquables suivants : (1) La réaction ne nécessite pas de catalyseurs métalliques coûteux; (2) la réaction ne nécessite pas l'utilisation de bases fortes ayant des risques potentiels sur la sécurité; (3) la réaction est sûre, les conditions sont modérées, le rendement est élevé, les coûts sont faibles, la présente invention étant ainsi bénéfique pour une production industrielle. (3)
Patent CA-3137339-A1 (CA)
Inventor: RIVERA ABARCA MARCO ESTEBAN
IPC: H02M7/48
Filed: 2019-05-09
Abstract: La présente invention concerne, sans s'y limiter, le domaine de l'électronique de puissance et la régulation non linéaire, et notamment une structure de topologie d'un convertisseur de puissance multiniveau de type pont en cascade. La présente invention concerne une nouvelle configuration de convertisseur de puissance qui comprend un bloc fonctionnel et se compose d'une faible quantité de dispositifs; cinq sources de tension de courant continu, neuf interrupteurs à semiconducteur et deux diodes à semiconducteur. Les interrupteurs (1) et (2) sont des dispositifs complémentaires entre eux. Par ailleurs, l'interrupteur S<sub>3</sub> correspont à un interrupteur bidirectionnel. La présente invention concerne, en outre, une pluralité de blocs fonctionnels connectés en série, chacun d'eux présentant la configuration du circuit.
Patent CA-3139063-A1 (CA)
Title: Kcnt1 inhibitors and methods of use
Inventor: MARTINEZ BOTELLA GABRIEL
IPC: C07D231/02
Filed: 2020-05-01
Abstract: The present invention is directed to, in part, compounds and compositions useful for preventing and/or treating a neurological disease or disorder, a disease or condition relating to excessive neuronal excitability, and/or a gain-of-function mutation in a gene (e.g., KCNT1). Methods of treating a neurological disease or disorder, a disease or condition relating to excessive neuronal excitability, and/or a gain-of-function mutation in a gene such as KCNT1 are also provided herein.
Patent CA-3140605-A1 (CA)
Title: Device for lifting a load
Inventor: ROSSATO ORIETTA
IPC: B66F7/04
Filed: 2020-05-14
Abstract: Device (50) for lifting a load, particularly for lifting a motor vehicle, of the type comprising: - a column (2) with a carriage (8) sliding along said column (2), - a structure (16), which is associated with said carriage (8), for supporting the load to be lifted, - means (6) for moving said carriage (8) along said column (2), thus causing the load supporting structure (16) to rise and/or descend, characterized in that said supporting structure (16) of the load includes: - a single supporting arm (18) which, at a first end thereof, is articulated to said carriage (8), - a longitudinal arm (22) which is associated with said supporting arm (18), at the other end of said supporting arm (18), so as to be able to rotate with respect to said supporting arm (18), said longitudinal arm (22) being telescopic at one or, preferably, both of its two ends, - arms (26) which are provided at one or, preferably, both ends of said longitudinal arm (22) and which develop in a substantially transverse, or in any case angled, direction with respect to said longitudinal arm (22), said arms (26) being provided and/or configured to be engaged by members (28) to support and/or support the load to be lifted.
Patent CA-3140852-A1 (CA)
Inventor: REGAN PAUL
IPC: A61J1/03
Filed: 2021-12-01
Abstract: An add-on medicine carrier comprising a container, a lid structure and an attachment mechanism. The container has at least one sidewall coupled adjacent one end to a base wall to define a chamber sized to receive at least one dose of a medication. The lid structure is configured to detachably mate adjacent to an opposing end the one or more sidewalls. The attachment mechanism is on an outer surface of the base wall to detachably secure the container to a surface of a mobile device.
Patent CA-3143972-A1 (CA)
Inventor: TRUONG AHN
IPC: G01C21/34
Filed: 2020-07-13
Abstract: Systems and methods for route mapping with familiar routes include striking a balance between optimal routes from standard navigation systems minimizing time and distance and a mapping component that suggests familiar routes based on a user's route history. New routes including one or more familiar routes may be suggested to the user when they are not too far out of the way or take too long compared to the optimal routes and when they may be preferable or more comfortable.
Patent CA-3144986-A1 (CA)
Title: Enhancing aav-mediated transduction of ocular tissues with hyaluronic acid
Inventor: BOYE SHANNON E
IPC: A61K31/728
Filed: 2020-06-26
Abstract: Disclosed herein are compositions of rAAV particles and methods for administrating rAAV particles having enhanced transduction properties.
Patent CA-3148386-A1 (CA)
Title: Contamination determination of biosensors used in analyte measurement systems
Inventor: MCCOLL DAVID
IPC: G01N27/327
Filed: 2019-07-24
Abstract: A method for determining contamination of a biosensor in which the biosensor is loaded into a test meter and a sample is then applied. First and second predetermined test voltages are applied between spaced electrodes of the biosensor for respective first and second predetermined time intervals. First and second current values are measured during the respective first and second predetermined time intervals. Reference values are determined based on the measured first and second current values. Based on one or more of the reference values, a determination of contamination is made. Reporting of the analyte concentration of the sample can be suppressed based on the determination.
Patent CA-3149991-A1 (CA)
Inventor: HARMER STUART WILLIAM
IPC: G01S13/88
Filed: 2020-09-03
Abstract: Selon un aspect, l'invention concerne un système permettant d'obtenir des propriétés diélectriques d'un objet, qui comprend une pluralité d'émetteurs-récepteurs destinés à générer un rayonnement dans la région de micro-ondes ou d'ondes millimétriques du spectre électromagnétique. Les émetteurs-récepteurs sont positionnés dans des relations spatialement fixes les uns par rapport aux autres. Le système comprend en outre un dispositif de commande permettant d'activer sélectivement les émetteurs-récepteurs de façon à exposer au moins une partie de l'objet à un rayonnement et à détecter au moins une partie du rayonnement réfléchi par ladite partie de l'objet en réponse à l'exposition à un rayonnement, chacun des émetteurs-récepteurs activés générant un signal en réponse à la détection du rayonnement réfléchi. Les signaux réfléchis sont analysés pour déterminer une pluralité de coefficients de réflectivité correspondant à différents emplacements discrets de l'objet, et les coefficients de réflectivité servent à déterminer la permittivité complexe des emplacements discrets.
Patent CA-3150256-A1 (CA)
Title: Barrier coating layer for an expandable member wellbore tool
Inventor: FRIPP MICHAEL LINLEY
IPC: E21B41/02
Filed: 2019-12-20
Abstract: Disclosed herein are aspects of a barrier coating layer of an expandable member wellbore tool for use in a wellbore. The barrier coating layer, in one aspect, covers at least a portion of the outer surface of the expandable member and has a composition formulated to react with a wellbore fluid and erode within a predetermined amount of time to allow a wellbore fluid to contact and hydrolyze the expandable member.
Patent CA-3151090-A1 (CA)
Title: Patient immobilization device, system and method for immobilizing a patient
Inventor: VOGELE MICHAEL
IPC: A61G7/05
Filed: 2020-04-24
Abstract: The invention relates to a patient immobilization apparatus (100) comprising a planar element (105) made of a non-woven fabric. The planar element (105) has an elongate middle section (110) and a plurality of arms (120; 130), which extend out laterally on both sides of the middle section (110). The patient immobilization apparatus (100) can be provided to the end user, preferably in a folded state. In the folded state, each of the arms (120; 130) is folded laterally on the elongate middle section (110). Parts of the elongate middle section (110), having the arms (120; 130) folded laterally thereon, are advantageously additionally foldable onto each other in the longitudinal direction. Each arm (120; 130) can be folded laterally in part on itself before it is folded laterally on the elongate middle section (110).
Patent CA-3151293-A1 (CA)
Title: Procede et appareil pour la signalisation de parametres de quantification de chrominance
Inventor: CHERNYAK ROMAN IGOREVICH
IPC: H04N19/124
Filed: 2020-09-23
Abstract: L'invention concerne un procédé pour la quantification inverse d'un bloc courant d'une image. Le procédé consiste à : recevoir un flux binaire ; obtenir un drapeau de commande de résidu de composante de chrominance commun (JCCR) à partir du flux binaire ; obtenir des informations de mappage de chrominance à partir du flux binaire sur la base du drapeau de commande JCCR ; obtenir au moins un paramètre de quantification de chrominance (QP) décalé par rapport au flux binaire sur la base du drapeau de commande JCCR ; obtenir une valeur QP pour le bloc de chrominance courant sur la base des informations de mappage de chrominance obtenues et du ou des décalages QP de chrominance obtenus ; exécuter une quantification inverse sur le bloc de chrominance courant à l'aide de la valeur QP déterminée.
Patent CA-3153629-A1 (CA)
Title: Analyses de fluide et constructions de capteurs utilisant des benzenes hexasubstitues
Inventor: HANES ROBERT E
IPC: G01N33/543
Filed: 2020-09-10
Abstract: Les cycles phényliques constituent un échafaudage robuste pour la conception moléculaire, en raison du nombre limité d'atomes de carbone dans le cycle et de la géométrie fixe qui se trouve entre eux. Les groupes alternés des benzènes hexasubstitués peuvent être dirigés vers les faces opposées du cycle phénylique, de telle sorte que les groupes réactifs orthogonaux sont dirigés vers les faces opposées pour faciliter à la fois la fixation en surface et l'introduction de fonctionnalités appropriées pour favoriser la détection d'analytes. Des benzènes hexasubstitués pouvant se lier de manière covalente à une surface et ayant des fonctionnalités susceptibles de favoriser la détection d'un ou plusieurs analytes dans les fluides peuvent être obtenus. Une réponse analytique des benzènes hexasubstitués ou une modification de ceux-ci peut être corrélée à une quantité d'au moins un analyte présent dans un fluide, y compris les fluides complexes à phase unique et à phases multiples.
Patent CA-3156902-A1 (CA)
Title: Compositions, devices and kits for selective internal radiation therapy
Inventor: D'ARIENZO MARCO
IPC: A61N5/10
Filed: 2020-10-31
Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
Patent CA-3161024-A1 (CA)
Inventor: SUN JASON J
IPC: C07K16/18
Filed: 2020-12-18
Abstract: Antibody fusions comprising any antibody or fragment thereof, operably linked, and expressed as a fusion with a label of interest. Plasmids, vectors, host cells, methods, and kits comprising the same are provided. The antibody fusions are useful in the diagnostic and reagent setting.
Patent CA-3166434-A1 (CA)
Inventor: KARREMANS ADRIANUS RUTGERUS ANTONIUS
IPC: A21D13/42
Filed: 2018-09-06
Abstract: The invention relates to a method for preparing a flour tortilla, comprising - preparing a tortilla dough from cereal flour and fat particles, which fat particles at least substantially consist of triglycerides of saturated fatty acids having 8-22 carbon atoms; - shaping the tortilla dough into a tortilla shape; and - heating the shaped tortilla dough, thereby obtaining the flour tortilla. The invention further relates to a flour tortilla dough, comprising fat particles dispersed therein, which fat particles at least substantially consist of triglycerides of saturated fatty acids having 8-22 carbon atoms, and to a flour tortilla that can be obtained by a method according to the invention or made from dough according to the invention.