baber/WOPTO huggingface dataset:
Patent ES-8400407-A1 (ES)
Title: 2(1H)-pyridinones and preparation thereof.
IPC: C07D213/85
Filed: 1982-09-07
Abstract: Novel 1-R1-3-Q-5-(3-R min -4-R sec -phenyl)-6-R-2(1H)-pyridinones where R1 is hydrogen, lower-alkyl or lower-hydroxyalkyl, R is lower-alkyl and, R min and R sec are each hydrogen, amino or hydroxy, at least one of R min or R sec being other than hydrogen, or R is nitro and R sec is hydroxy, are useful as cardiotonics. Also known compounds where R is hydrogen are useful as cardiotonics. Both novel and known compounds can be prepared by a novel process which comprises reacting 1-R1-1,2-dihydro-2-oxo-5-(3-R min -4-R sec -phenyl)-6-R-nicotinonitrile, where R1 and R are defined as above, R min is hydrogen, hydroxy, methoxy or amino and R sec is hydrogen, hydroxy, amino or methoxy, at least one of R min and R sec being other than hydrogen, or R min is nitro and R sec is hydroxy with 85% phosphoric acid.
Patent ES-8502107-A1 (ES)
Title: process for the production of isochromans and indane precursors used in this process.
IPC: C07C15/44
Filed: 1982-12-29
Abstract: Process for the preparation of indanes with the formula < CHEM > wherein R3 represents a hydrogen atom or a methyl group at least one of R1 and R2 represents a methyl group and the other represents a hydrogen atom or a methyl group and R4 and R5 which may be the same or different represent alkyl groups having form 1 to 3 carbon atoms in which alkenes selected from the group consisting of propylene, 2-methyl-but-1-ene, 2-methyl-but-2-ene, 2-methyl-pent-1-ene, 2-methyl-pent-2-ene, 3-methyl-but-1-ene, isobutylene and diisobutylene, are reacted with a styrene with the formula < CHEM > wherein R1 represents a hydrogen atom or a methyl group in the presence of phosphoric acid. The indanes (or their precursors) can be reacted with an alkylen oxide and subsequently with formaldehyde to yield isochromanes.
Patent ES-8405764-A1 (ES)
Title: 4-Substituted mercapto-2-oxo-1-azetidinesulfonic acid salts and process for their preparation.
IPC: C07D205/095
Filed: 1983-01-12
Abstract: Antibacterial activity is exhibited by beta -lactams having a sulfonic acid salt substituent in the 1-position, an acylamino substituent in the 3-position and a substituted mercapto substituent in the 4-position.
Patent ES-8404672-A1 (ES)
Title: Cyclohexane dione derivatives, their use as herbicides, herbicidal compositions containing them, and methods of preparing them.
IPC: C07C49/255
Filed: 1983-01-28
Abstract: The invention concerns novel compounds of the formula I < IMAGE > I wherein: X is selected from halogen, nitro, cyano, alkyl, substituted alkyl, hydroxy, alkoxy, substituted alkoxy, alkenyl, alkynyl, alkenyloxy, alkynyloxy, acyloxy, alkoxycarbonyl, alkylthio, alkylsulfinyl, alkylsulfonyl, sulfamoyl, substituted sulfamoyl, amino, substituted amino, and the groups formyl and alkanoyl and the oxime, imine and Schiff base derivatives thereof R1 is selected from hydrogen, alkyl, alkenyl, alkynyl, substituted alkyl, alkylsulfonyl, arylsulfonyl, acyl and an inorganic or organic cation R2 is selected from alkyl, substituted alkyl, alkenyl, haloalkenyl, alkynyl and haloalkynyl R3 is selected from alkyl, fluoroalkyl, alkenyl, alkynyl, and phenyl m is an integer chosen from 3 to 5. The compounds of the invention show herbicidal properties and plant growth regulating properties and in further embodiments the invention provides processes for the preparation of compounds of formula I, intermediates useful in the preparation of the compounds of formula I, compositions containing as active ingredient a compound of formula I, and herbicidal and plant growth regulating processes utilizing compounds of formula I.
Patent ES-8401059-A1 (ES)
Title: Bicyclic phenol ethers, process for their preparation and medicines containing these compounds.
IPC: A61K31/34
Filed: 1983-03-10
Abstract: The present invention provides bicyclic phenol ethers of the general formula: < IMAGE > (I) wherein R1 is a hydrogen atom or a lower alkyl radical, R2 is a hydrogen atom or an acyl radical, X is an oxygen or sulphur atom or an -NH- group Y is a -CO-CHR3- group or a < IMAGE > group R3 is a hydrogen atom, a lower alkyl radical which can be optionally substituted by an aryl radical, or a cycloalkyl radical containing 3 to 7 carbon atoms and R4 and R5, which can be the same or different, are hydrogen atoms, lower alkyl radicals, lower alkyl radicals, alkenyl radicals containing 2 to 16 carbon atoms, which can be optionally substituted by an aryl radical, or an aryl radical or R4 and R5, together with the carbon atom to which they are attached, form a cycloalkyl ring containing 3 to 7 carbon atoms and the salts thereof with pharmacologically acceptable acids. The present invention also provides processes for the preparation of these compounds, as well as pharmaceutical compositions containing them.
Patent ES-8503018-A1 (ES)
Title: Bonded reinforced plastic structures.
IPC: B29C65/52
Filed: 1984-02-02
Abstract: A bonded reinforced plastic structure which comprises reinforced plastic parts of sheet molding compound or bulk molding compound, coated with a primer coat and bonded together with a thermoplastic block copolymer. The primer coat comprises a moisture-curable polyisocyanate. The block copolymer comprises from 40 to 80 weight percent crystalline polyester or polyamide segments and 20 to 60 weight percent amorphous polyamide or polyether segments and has a crystalline melting point of at least 155 DEG C. The bonded structure is adapted to survive the hot environment of paint curing ovens.
Patent ES-8504256-A1 (ES)
Title: DNA sequence for messenger RNA encoding poly:peptide
IPC: C12P21/02
Filed: 1984-04-16
Abstract: Construction of a DNA sequence for a messenger RNA encoding a polypeptide comprising a functional protein, or a bioactive part of it, is effected by (a) provision of a fragment of the DNA sequence encoding a C-terminal portion of the polypeptide (the fragment conforming in sequence to the natural sequence of this polypeptide); (b) provision of a fragment of the DNA sequence encoding the N-terminal portion of the poly-peptide; and (c) ligation of the 2 fragment (a) and (b) in proper reading frame relation to one another. Fragment (b) has its nucleotides sequentially arranged to provide on transcription messenger RNA that (1) properly encodes the respective portion of the amino acid sequence of the polypeptide and (2) demonstrates levels of conformational structure insufficient to interfere with its accessibility for efficient ribosomal translation. The DNA sequence is exclusive of the hybrid DNA sequence of human growth hormone (as dislosed in Nature 281,544 (1971)).
Patent ES-8602040-A1 (ES)
Title: Absorbent vegetable material and process for making same.
IPC: D21C9/10
Filed: 1984-08-10
Abstract: Highly absorbent, pectin-containing materials from vegetable origin are disclosed. A process for preparing such materials from pectin-containing agricultural by-products is also disclosed.
Patent ES-8607905-A1 (ES)
Title: New carboxy-alkyl-heterocyclyl-alkyl-indane(s) and analogues - useful as strong selective inhibitors of thromboxane a2
IPC: A61K31/415
Filed: 1984-08-24
Abstract: Indane and tetrahydronaphthalene derivs. of formula (I) and their salts are new. Z = CH2 or CH=CH; one of R1, R2 = (CH2)m-COOR3; and the other = (CH2)n-X; X = 1-imidazolyl, 5-thiazolyl or pyridyl; R3 = H or 1-6C alkyl; n = 1-6; m = 0-5. (I) where R1 = (CH2)n-X; R2 = (CH2)m-COOR3; n = 1 or 2; m = 0 or 1 are specifically claimed.
Patent ES-8607318-A1 (ES)
Title: Chemical compounds
IPC: C07D501/56
Filed: 1985-04-08
Abstract: 7-[2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(substituted)-iminoacetamido]-3 -[3-(quaternaryammonio)-1 - propen-1-yl]-3-cephem-4-carboxylates of the formula < IMAGE > in which R<1> and R<2> are as defined herein and < IMAGE > is a quaternary ammonio group as defined herein, and salts, solvates, hydrates and esters thereof, are potent antibacterial agents. Processes for their preparation and intermediates in such processes are described.
Patent ES-8603591-A1 (ES)
Title: Method and device for the automatic oversuction on electrolysis containers for the production of aluminum.
IPC: C25C3/06
Filed: 1985-04-30
Abstract: Appts. for increased suction extraction of hot waste material in dusty or gaseous form comprises a series of vessels closed at its periphery by two or more covers. The covers are sealed together and are supported on the periphery of the vessel. A duct is connected to a centralised suction extraction system positioned over each vessel to collect the waste. The temp. T of the gases in each duct is measured and compared with reference values T1 and T1', when T is not more than T1 the suction extraction is increased and stopped when T is at least equal to T1'. The process is also claimed.
Patent ES-8606608-A1 (ES)
Title: Casing seal attachment.
IPC: F22B37/20
Filed: 1985-05-03
Abstract: A transition seal plate for connecting a casing to a membrane wall of a vapor generator. The plate has a generally corrugated edge which is weld connected to the membrane wall and is formed with arcuate surfaces which overlap circumferential surface portions of the tubes within the membrane wall, and protrusions which project into the spaces between the circumferential surface portions.
Patent ES-8702658-A1 (ES)
Title: Ultrasonic nondestructive tubing inspection system.
IPC: G01N29/28
Filed: 1985-06-24
Abstract: A system for measuring the extent of tube wall erosion in an inspection region of a heat exchanger tube of a nuclear steam generator, uses an ultrasonic means driven helically inside the eroded tube which may be filled with a fluid (e.g., water) to minimize ultrasonic wave attenuation. A control means cooperates with the ultrasonic means to produce a map of the tube wall thickness in an inspection region.
Patent ES-8604195-A1 (ES)
Title: Indole compounds.
IPC: C07D401/04
Filed: 1985-07-12
Abstract: 1-Pyridyl-indole derivs. of formula (I), their pyridyl N-oxides, and their salts are claimed. In (I), Ar = opt. lower alkyl-substd. 3- or 4-pyridyl R1 = H, halogen, CF3, lower alkyl, OH, acyloxy, etherified OH, lower alkylthio, lower alkylsulphinyl and/or lower alkylsulphonyl, or two adjacent residues R1 can form an alkylenedioxy gp. p = 1 or 2 R2 = H or lower alkyl R3, R4 = H or -A-B, at least one (but not both) being H A = 1-12C alkylene, 2-12C alkynylene or alkenylene, lower alkylenephenylene, lower alkylene-(thio or oxy)-lower alkylene, (lower alkylene) -phenylene-(lower alkylene or alkenylene) or alkadienylene with 4-12C atoms B = COOH, esterified carboxy, CONH2, mono- or di-(lower alkyl)carbamoyl, CN, hydroxycarbamoyl, 5-tetrazolyl or opt. lower alkyl-substd. 4,5-dihydro-2-oxazolyl. - Specifically claimed are 11 cpds., including 3-(4-carboxybutyl) -N-(3-pyridyl)indole and (E)-3-(4-carboxy-3-pentenyl) -N-(3-pyridyl)indole.
Patent ES-8603669-A1 (ES)
Title: Elimination of limonene and limonoic acid from citrus fruit juices
IPC: A23L/
Filed: 1985-07-03
Abstract: The process consists of (a) separating in (1) the pulp from juice obtained by squeezing the citrus fruit; (b) eliminating in (2) the limonene and limonoic acid from the juice, using an adsorbent of activated carbon type; (c) washing in (4) the pulp at least once, with part of the treated juice and/or water; (d) separating in (6) the wash liquor from the washed pulp; and (e) homogenising the washed pulp with the treated juice, the weight of pulp being equal to the weight of cloudy juice at the start of the treatment. The juice obtained has agreeable organoleptic characteristics suitable for industrial manufacture.
Patent ES-8705237-A1 (ES)
Title: Catheter for detecting intracardiac electric potential fields
IPC: A61M23/00
Filed: 1985-08-09
Abstract: A distal end portion is provided with a series of sensor electrodes distributed over its surface. A series of insulated electrical conductor wires are connected to respective sensor electrodes and to a unit for receiving and processing signals picked up by the electrodes. - The distal end portion is ellipsoidal shaped that, when it is inserted in a cardiac chamber, the sensor electrodes are spaced from the wall of the cardiac chamber, and has a volume of between 1/5 and 1/10th of the volume of the chamber. The electrodes are distributed on a series of circumferences lying in planes spaces from each other and perpendicular to the major axis of the ellipsoidal end.
Patent ES-8606301-A1 (ES)
Title: Prepn. of antifungal 2-butanol deriv.
IPC: C07D249/08
Filed: 1985-12-18
Abstract: Prepn. comprises (a) reacting 1-(4-chlorophenoxy) -3,3-dimethyl-2-butanone with diethyl-(1,2,4-triazol-1-yl)methyl phosphonate in basic medium, e.g. potassium tert-butoxide, sodium amidate and sodium hydrate to give 2-((4-chlorophenoxy) methyl) -3,3-dimethyl -1-(1,2,4-triazol-1-yl) -2-butene (b) oxymercurating in presence of mercuric salts, e.g. mercuric sulphate, nitrate or acetate and (c) reducing with sodium hydrates in basic medium to give cpd. (I). Steps, (b) and (c) take place in solvents like dioxan-1,2-dimethoxyethane.
Patent ES-8707020-A1 (ES)
Title: Colour cathode ray tube including a channel plate electron multiplier.
IPC: H01J31/12
Filed: 1986-02-10
Abstract: A colour cathode ray tube including a screen (16) comprising at least two sets of phosphor stripes luminescing in different primary colours. A channel plate electron multiplier (44) is mounted parallel to, but spaced from, the screen (16). The electron multiplier (44) comprises a stack of juxtaposed substantially planar apertured dynodes (DI to Dn) with the apertures therein aligned to form channels. An apertured extractor electrode (48) is mounted on the output side of the electron multiplier (44). Preferably two or more foraminous deflector electrodes (50, 52) are mounted on the extractor electrode. The apertures in the foraminous deflector electrodes (50, 52) have the same pitch as the channels of the electron multiplier but are offset laterally relative to each other and to the axes (A) of the channels by amounts which allow the emergent electron beam from each channel to pass through to the screen (16) without impinging upon the deflector electrodes (50, 52). By applying a potential difference between the deflector electrodes (50, 52) an electron beam emerging from its respective channel is deflected laterally onto a respective one of its associated group of phosphor stripes. The apertures in the deflector electrodes (50, 52) may be circular, elliptical or polygonal for example square, rectangular or hexagonal.
Patent ES-8800435-A1 (ES)
Title: Immunoassays for denatured protein analytes, particularly HB Alc, and monoclonal antibodies thereto.
IPC: A61K39/395
Filed: 1986-07-01
Abstract: Binding of a particular protein by an antibody reagent involving denaturation of the protein and use of an antibody reagent specific for binding a linear peptide epitope therein. Denaturation by chemical or physical means effectively exposes or enhances the exposure of the linear peptide epitope for binding by the antibody reagent which is preferably raised against a synthetic peptide immunogen. The technique is particularly useful in performing immunoassays for protein analytes, such as a glycosylated protein, in aqueous test samples. Monoclonal antibodies are also provided which are specific for the glucosylated terminal peptide sequence in the beta-subunit of human hemoglobin and are therefore useful in the determination of Hb Alc.
Patent IE-902035-A1 (IE)
Title: Methods of making high performance compacts
IPC: H01H71/00
Filed: 1990-06-07
Abstract: High density compacts are made by providing a compactable particulate combination of Class 1 metals selected from at least one of Ag, Cu and Al, with material selected from at least one of CdO, SnO, SnO2, C, Co, Ni, Fe, Cr, Cr3C2, Cr7C3, W, WC, W2C, WB, Mo, Mo2C, MoB, Mo2B, TiC, TiN, TiB2, Si, SiC, Si3N4, usually by mixing powders of each, step (1); uniaxially pressing the powders to a density of from 60% to 95%, to provide a compact, step (2); hot densifying the compact at a pressure between 352 kg/cm2 (5,000 psi) and 3,172 kg/cm2 (45,000 psi) and at a temperature from 50 DEG C. to 100 DEG C. below the melting point or decomposition point of the lower melting component of the compact, to provide densification of the compact to over 97% of theoretical density; step (3); and cooling the compact, step (4).
Patent IE-913068-A1 (IE)
Title: Heterocyclic compounds
IPC: C07D239/70
Filed: 1991-08-30
Abstract: The invention relates to 3-aryluracils of the general formula  in which R1 is hydrogen, C1-C4-alkyl, C3-C4-alkenyl, C3-C4-alkynyl, C2-C6-alkoxyalkyl or C1-C4-haloalkyl, R2 is hydrogen, C1-C6-alkyl, C2-C6-alkoxyalkyl, C4-C7-cycloalkenyl- C1-C4-alkyl which is optionally substituted on the ring by 1 to 3 C1-C3-alkyl groups, or is C3-C4-alkenyl, C4-C7-cycloalkenyl- C3-C5-alkenyl which is optionally substituted on the ring by 1 to 3 C1-C3-alkyl groups, or is aryl-C3-C5-alkenyl, C3-C4-alkynyl, C4-C7-cycloalkenyl-C3-C5-alkynyl which is optionally substituted on the ring by 1 to 3 C1-C3-alkyl groups or is aryl-C3-C5-alkynyl, R3 is hydrogen or halogen, R4 is hydrogen, halogen or C1-C4-alkyl and R5 is C1-C4-alkyl or C1-C4-haloalkyl, or R4 and R5 together are tri- or tetramethylene, with the proviso that, if R5 is C1-C4-haloalkyl, R1 is other than C1-C4-haloalkyl and R2 is other than hydrogen, and the corresponding enol ethers of those compounds of the formula I in which R1 is other than hydrogen or C1-C4-haloalkyl, and salts of those compounds of the formula I in which R1 and/or R2 are hydrogen. The compounds according to the invention, that is to say the compounds of the formula I and the enol ethers and salts thereof, are herbicidally active and suitable as active substances of herbicides. The invention therefore also embraces herbicides which contain compounds according to the invention as active substances, processes for the preparation of these compounds, and the use of the compounds, or agents, for controlling weeds.
Patent IE-913751-A1 (IE)
Title: Synergism of hiv reverse transcriptase inhibitors
IPC: A61K31/443
Filed: 1991-10-25
Abstract: The combination of certain aminopyridones and anti-HIV nucleoside analogs has been found to synergistically inhibit HIV reverse transcriptase. This combination is useful in the prevention or treatment of infection by HIV and the treatment of AIDS, either as a combination of compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in further combination with other antivirals, anti-infectives, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.
Patent IE-914206-A1 (IE)
Title: Method of washing in particular for washing machines and¹dishwashers using either a low temperature or cold water¹with low tension and immersed electrodes
Inventor: PANDOLFO SALVATORE MARIO
IPC: D06F39/04
Filed: 1991-12-04
Abstract: A method of washing consisting of one,two or more metal electrodes directly immersed in the wator in the 5 place of the usual heating element.These electrodes are - connected to a transformer, preferably a piloted reluctance type, so as to isolate and decouple from the mains and are capable of activating the cleansing agent proposed for washing even with cold water.
Patent IE-904215-A1 (IE)
Title: Cellular or foamed hydraulic compositions
IPC: C04B28/00
Filed: 1990-11-21
Abstract: A cellular or foamed hydraulic composition, comprising about 100 parts by weight of a hydraulic substance, about 25 to less than about 70 parts by weight water and about 0.01 to about 10 parts by weight of a polymeric foam stabilizer having a weight average molecular weight from about 1,000 to about 20,000 and comprising a homopolymer or copolymer of C1-C12 alkyl carboxylic acids, may be used in or as a floor substrate, roof substrate or wall substrate.
Patent IE-904598-A1 (IE)
Title: New process for the preparation of nojirimycin and related compounds
Inventor: ANZEVENO PETER BIAGIO
IPC: C07H13/12
Filed: 1990-12-19
Abstract: The present invention relates to an efficient new route for the preparation of (+)-nojirimycin and (+)-1-deoxynojirimycin which involves the steroselective reductive amination of 1,2-O-isopropylidene-5-oxo- alpha -D-glucuronolactone. The reductive amination uses particular oximes of the 5-oxo compound.
Patent IE-920768-A1 (IE)
Title: Proteins and nucleic acids
Inventor: EDWARDS RICHARD MARK
IPC: A61K38/00
Filed: 1992-03-10
Abstract: The nucleic acid and amino acid sequence of equine epidermal growth factor (EGF) and some variants thereof, are disclosed. Also mentioned are vectors and hosts for use in expressing nucleic acid to produce equine EGF (and its variants) by translation. Pharmaceutical compositions containing equine EGF (and its variants) are useful in the healing of wounds and in particular tendonitis in horses.
Patent IE-921182-A1 (IE)
Title: Protective catheter device
Inventor: KAUFMAN JERRY M
IPC: A61M5/158
Filed: 1992-04-14
Abstract: Protective catheter devices are disclosed including a barrel for housing a catheter including a needle extending therefrom. The catheter is slidably retained within the barrel between a fully retracted position and an extended position, in which the needle can be inserted into a patient, and the device includes a locking mechanism for controlling the position of the needle within the barrel, which includes at least two positions; namely, a first position in which the needle is freely slidable within the barrel and a second position in which the needle is locked in its retracted position within the barrel, such that the needle cannot be displaced from its retracted position without repositioning the locking mechanism.
Patent IE-921666-A1 (IE)
Title: Radio system with measurement and adjustment of transfer delay
Inventor: BRYDON ALASTAIR NORMAN
IPC: H04L7/00
Filed: 1992-07-01
Abstract: A radio system has a control centre 10 for providing signals for transmission to a plurality of radio transmitters (13, 14, 15 & 16) each connected to the central source by a digital data link (12). A delay equaliser (11) measures the variable transfer delay of each data link and adjusts the transfer delay of the transfer links to equalise the transfer delays to transmitters, so that the signals from the control can be transmitted from the transmitters substantially in time synchronism. <IMAGE>
Patent IE-940879-A1 (IE)
Title: Liquid anthelmintic selenium compositions
Inventor: HARVEY COLIN MANSON
IPC: A61K9/00
Filed: 1994-11-10
Abstract: A stable liquid anthelmintic composition containing an active ingredient chosen from the groups of avermectins and milbemycins in combination with a liquid carrier and one or more selenium salts selected from the group of selenium salts which in the chosen liquid carrier do not break down the avermectins or milbemycins present in the composition. When the liquid carrier is a non-aqueous carrier, the selenium salt is chosen from the group omprising selenium oxides, selenium dioxide, selenium trioxide, and selenous acid. When the liquid carrier is an aqueous carrier, the selenium salt is chosen from the group comprising selenium edetate, ethylene diamino tetracetic acid selenium as a sodium salt, selenium amino acid chelates, selenium aninoates, selenium ascorbate, selenium aspartates and selenium proteinates.
Patent IE-980490-A1 (IE)
Title: A process for the validation of culture media
Inventor: GEOGHEGAN ANITA MARY
IPC: C12Q1/22
Filed: 1998-06-18
Abstract: A process for making sterile, functional media in an autoclave.  Dehydrated media is dissolved in water purified to predetermined levels and sterilised by autoclaving.  The media is tested for pH, growth promotion ability, sterility and stored under predetermined optimal conditions of light and temperature, not exceeding a predetermined time period.  The prepared media ensures reliable results when used to test microbiological assessment of food, pharmaceutical, chemical and agrochemical products.