baber/WOPTO huggingface dataset:
Patent BR-PI1011144-B1 (BR)
Title: proteína precursora, sequência de ácido nucleico, cassete de expressão, vetor recombinante, método para produzir um peptídeo desejado, e, uso de um peptídeo anfifílico
Inventor: BURGHARD LIEBMANN
IPC: C12N15/74
Filed: 2010-06-02
Abstract: PROTEÍNA PRECURSORA, SEQUÊNCIA DE ÁCIDO NUCLEICO, CASSETE DE EXPRESSÃO, VETOR RECOMBINANTE, MÉTODO PARA PRODUZIR UM PEPTÍDEO DESEJADO, E, USO DE UM PEPTÍDEO ANFIFÍLICO A presente invneção diz respeito a proteínas precursoras de auto-montagem repetitiva, sequências de ácido nucleico e contruções de expressões codificando-as, e a métodos para produção recombinante de peptídeos com o uso de tais proteínas precursoras.
Patent EA-010684-B1 (EA)
Title: Process for the preparation of crystalline polymorph of a platelet aggregation inhibitor drug
Inventor: KOTAY NAGY PETER
IPC: C07D495/04
Filed: 2004-06-30
Abstract: The present invention relates to a new method of preparation of the polymorph form 1 of methyl (S)-(+)-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridine-5-yl-acetate hydrogensulfate of the formula (I).
Patent EA-013738-B1 (EA)
Title: Treating bone-related disorders with selective androgen receptor modulators
Inventor: DALTON JAMES
IPC: A61K/
Filed: 2004-10-12
Abstract: This invention provides method of treating a bone-related disorders, for example osteoporosis, osteopenia, increased bone resorption, bone fracture, bone frailty and/or loss of bone mineral density (BMD), by administrating a therapeutically effective amount of a selective androgen receptor modulator (SARM) represented by a structure of formula IX or XI:
Patent EA-011764-B1 (EA)
Title: Isoxazoline-substituted benzamide compound and pesticide
Inventor: MITA TAKESHI
IPC: C07D261/04
Filed: 2005-03-04
Abstract: An isoxazoline-substituted benzamide compound of the general formula: (1) or a salt thereof, [wherein each of, Aand Aindependently represents a carbon atom or nitrogen atom; G a benzene ring, etc.; X a halogen atom, C-Chaloalkyl, etc.; Y a halogen atom, C-Calkyl, etc.; Ran arbitrarily substituted with R, C-Calkyl, C-Calkenyl, N(R)R, etc.; Ra hydrogen atom, (C-C)alkoxy(C-C)alkyl, etc.; Ra C-Chaloalkyl, etc.; Ra halogen atom, cyano, phenyl substituted with (Z)p1, D-1 to D-60, E-1 to E-49, etc.; Ra phenyl, phenyl substituted with (Z)p1, etc.; Ra hydrogen atom, C-Calkyl, etc.; Z a halogen atom, nitro, C-Calkoxy, etc.; D-1 to D-60 a 5- or 6-membered aromatic heterocycle; E-1 to E-49 a 5- or 6-membered saturated heterocycle; m an integer of 0 to 5; n an integer of 0 to 4; and p1 an integer of 1 to 5], or a salt thereof. Further, there is provided a pesticide comprising any of these compounds.
Patent EA-011655-B1 (EA)
Title: Use of pyrazole derivative for preparing medicines useful for preventing or treatment rental diseases
Inventor: BENSAID MOHAMMED
IPC: A61K31/454
Filed: 2006-02-17
Abstract: The invention concerns the use of a cannabinoid CBreceptor antagonist compound, alone or combined with another active principle, derived from pyrazole, for preparing drugs useful for preventing and treating renal diseases.
Patent EA-016157-B1 (EA)
Title: A method for impregnation of porous objects
Inventor: PETERSEN LARS BORTHY
IPC: C04B41/45
Filed: 2007-06-13
Abstract: The invention relates to a method for impregnation of porous objects comprising the following steps i)-v): i) applying an injection layer of a material comprising acrylic, epoxy or polyurethane onto the surface of at least part of the porous object and allowing at least part of said material to enter into the pores of said object utilizing subatmospheric or superatmospheric pressure; ii) allowing the porous object to return to an atmosphere of normal pressure; iii) optionally at least partly allowing the injection layer to harden; iv) applying a topcoat of acrylic, epoxy or polyurethane onto the area of the porous object impregnated with the injection layer: v) allowing the topcoat to harden; wherein the injection layer applied in step i) and/or the topcoat applied in step iv) comprises pulverized glass having a particle size of 0 run to 100 [mu]m. The invention also relates to porous objects obtained according to this method. The impregnated objects exhibits great strengths and resistance against wear of mechanical, chemical, thermal and/or biological nature.
Patent EA-016447-B1 (EA)
Title: A novel alpha-(n-sulfonamido)acetamide compound as an inhibitor of beta amyloid peptide production
Inventor: STARRETT JR JOHN E
IPC: A61K31/4245
Filed: 2008-10-14
Abstract: The present invention provides a novel alpha-(N-sulfonamido)acetamide compound, its pharmaceutical composition, processes thereof and a method for the treatment of Alzheimer's disease and other conditions associated with β-amyloid peptide.
Patent EA-020069-B1 (EA)
Title: Liquid formulation of conjugate
Inventor: HINDERER WALTER
IPC: A61K47/48
Filed: 2008-08-27
Abstract: The present invention relates to a liquid pharmaceutical composition comprising a granulocyte colony stimulating factor polypeptide conjugated with a polymer, the composition having a pH value in the range of 4.5 to 5.5. The composition further comprises a surfactant and optionally one or more other pharmaceutically acceptable excipients. Further, the composition of the invention is free from tartaric acid or salts thereof and from succinic acid and salts thereof as buffering agents and does not contain amino acids as stabilizer. The composition has a good storage stability and is especially useful for the prophylaxis and treatment of disorders and medical indications where granulocyte colony stimulating factor preparations are considered as useful remedies.
Patent EA-018042-B1 (EA)
Title: Absorbent article and method of producing the same
Inventor: KASHIWAGI MASAHIRO
IPC: A61F13/15
Filed: 2008-08-15
Abstract: To provide an absorbent article which sustains the flexibility of the front face sheet and shows no glossiness. A sanitary napkin (1) which comprises a front face sheet (2) forming the inner face in the body side, a back face sheet (3) forming the outer face in the cloth side, a liquid-absorbing structure (4) formed between these front and back faces (2, 3), and a cushion sheet (5) formed between the liquid-absorbing structure (4) and the front face sheet (2). The front face sheet (2) has multiple holes (6) that are formed for ensuring liquid-permeability. These holes (6) are formed all over the front face sheet (2) and penetrate the front face sheet (2) in the thickness direction. The front face sheet (2) has multiple peaks (13) toward the cushion sheet (5) side that are formed by a molding treatment. The peaks (13), which are almost round in shape, are formed at almost constant intervals all over the front face sheet (2). The molding treatment for forming the peaks (13) is carried out at a temperature lower than the melting point of the front face sheet (2).
Patent EA-022831-B1 (EA)
Title: Solid materials of {[2s,5r,8s,11s)-5-benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaaza-cyclopentadec-2-yl]acetic acid} and methods for obtaining them
Inventor: JONCZYK ALFRED
IPC: A61P35/00
Filed: 2010-05-20
Abstract: The present invention relates to novel solid materials of {[(2S,5R,8S,11S)-5-benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaaza-cyclopentadec-2-yl]acetic acid}, methods for producing them, and the use of said solid materials in pharmaceuticals.
Patent EA-018910-B1 (EA)
Title: Process for preparing composition comprising biologically active material
Inventor: NAYLOR ANDREW
IPC: A61K9/16
Filed: 2009-07-10
Abstract: A process for preparing microparticles comprising a biologically active material and a polymer and having a mean particle size expressed as the volume mean diameter (VMD) of from 10 to 500 [mu]m, wherein the biologically active material is substantially insoluble in the polymer, which process comprises: a) contacting a mixture of the biologically active material or a precursor thereof, the polymer or a precursor thereof and a processing aid with a supercritical fluid (SCF) which is capable of swelling the polymer under temperature and pressure conditions necessary to maintain the fluid in a supercritical state; b) allowing the supercritical fluid (SCF) to penetrate and liquefy the polymer, whilst maintaining the temperature and pressure conditions so that the fluid is maintained in a supercritical state; c) releasing the pressure to precipitate microparticles comprising the biologically active agent and the polymer.
Patent EA-020180-B1 (EA)
Title: A process for preparing an aqueous suspension of an organic pesticide compound
Inventor: FINCH CHARLES W
IPC: A01N25/04
Filed: 2010-07-13
Abstract: The present invention relates to a process for preparing an aqueous suspension of an organic pesticide compound, which has a solubility in water of not more than 2 g/l at 20°C and a melting point of not more than 110°C and which is capable of forming at least one crystalline modification, wherein the organic pesticide compound is present in the form of essentially crystalline particles, which process comprises: a) providing an aqueous emulsion of the organic pesticide compound, wherein the organic pesticide compound is present in the form droplets of an amorphous form of the organic pesticide compound, and b) addition of an aqueous suspension of said organic pesticide compound, wherein the organic pesticide compound is present in the form of essentially crystalline particles, wherein the addition in step b) is performed at a temperature below the melting temperature of the crystalline form of the organic pesticide compound.
Patent EA-022143-B1 (EA)
Title: Device of catadioptric telescope
Inventor: KLEVTSOV JURIJ ANDREEVICH
IPC: G02B7/185
Filed: 2012-10-30
Abstract: A device of catadioptric telescope comprises a main spherical mirror, a correction element comprising two lenses, having a quasi-proximal in the visible spectrum of dispersion coefficient, wherein the first lens following the ray path is made from a glass with greater refraction index serving as a secondary mirror, a three-lens isoplanatic compensator of off-axis aberration, the first lens of which is made as a quasi-afocal negative meniscus with its concavity overlooking the image plane, the second and third lenses are glued, the first surface of the glued block is flat, the rest surfaces with their concavity overlooking the image plane, or a two-lens lens afocal off-axis aberration compensator, the first lens following the ray path is a negative lens made from a glass of "flint" type as a quasi-afocal meniscus with its concavity overlooking the image plane, and the second positive lens is plano-convex lens made from glass of "cron" type with its convexity overlooking the image plane. The main mirror is rigidly fixed on a bushing with elastic leaves. The corrector has radial adjusting gaps in pairs: a reflecting lens carrier and a bearing ring carrier filled with an elastic seal composition after the adjustment completion. The adjusting devices are embodied as two spherical joints, stationary and movable, along the instrument optical axis. Three stretches of the corrector fixing part are positioned after each 120° along the circle and curved with radius of curvature equal to the length of their chord. The bushing end, opposite to the leaves, has a cylindrical collar, to which the bushing of the spherical joint is fixed by a threaded ring, and on that, from both collar sides, bearing rings are arranged abut against the collar by three radially-symmertrical projections, the bearing rings are fixed by stop crews. The rear cover is split, the adjusting screws are positioned in its rear side.
Patent EA-027097-B1 (EA)
Title: Electronic device control system and method
Inventor: KANE AJIT
IPC: H02P27/04
Filed: 2010-10-01
Abstract: There are provided a control system and method. An exemplars' method (3400) includes employing (3404) a look-up table to derive first waveform value data for a multi-phase reference waveform. The exemplary method also includes deriving (3406) second waveform value data corresponding to modifier data for the multiphase reference waveform. The modifier data is added (3408) into the reference waveform to produce a modified reference waveform. The exemplary method additionally includes generating (3410) a plurality of control signals from the modified reference waveform and controlling one or more electronic devices based on the mentioned control signals.
Patent EA-022602-B1 (EA)
Title: Diffuser for cleaning a fluff-laden component
Inventor: GRUNERT KLAUS
IPC: D06F58/24
Filed: 2011-07-04
Abstract: A cleaning diffuser (2) for a fluff-laden component (1) in a domestic appliance for caring for articles of laundry, such as a dryer or washer-dryer, the diffuser (2) being a substantial component of a rinsing arrangement by means of which rinsing fluid (5) can be fed to the component (1) in order to detach the fluff and carry it away, the diffuser (2) being disposed above the component (1) and designed to be suitable for building up dynamic pressure in the rinsing fluid in the diffuser (2) and dividing the rinsing fluid (5), after it has entered the diffuser (2), between two feed ducts (9a, 9b) which are at a distance from one another, are substantially parallel and terminate at the end of the diffuser in a pocket-like wall (10a, 10b) and which, relative to their entire duct length, have a three-dimensional transverse mutual connection in the form of a transverse chamber (11), wherein at least one outlet opening (14) having a width required for evenly distributing the rinsing fluid (5) over the fluff-laden component (1) is provided in the direction from the said connection to the lower side of the diffuser (2).
Patent EA-028279-B1 (EA)
Title: Molecularly imprinted polymer, methods of making and utilizing the same
Inventor: YIANNIKOURIS ALEXANDROS
IPC: A23L5/20
Filed: 2010-08-27
Abstract: The present invention relates generally to molecularly imprinted polymers (MIPs). In particular, the present invention relates to reusable, ecologically friendly MIPs that can be produced in relatively large quantities, methods of producing the same, and methods of utilizing the same (e.g., to sequester and/or adsorb target compounds (e.g., mycotoxins)). Polymers and methods of the invention find use in a variety of applications including dietary, therapeutic, prophylactic, food and beverage processing and manufacture, as well as research, quality control and traceability applications.
Patent EA-033142-B1 (EA)
Title: Type-4 tank for compressed natural gas containment
Inventor: NETTIS FRANCESCO
IPC: F17C13/08
Filed: 2011-12-05
Abstract: The present invention relates to a pressure vessel for containing or transporting pressurized gas. More particularly it relates to such vessels for containing or transporting compressed natural gas. The present invention also relates to a method of storing or transporting gas onshore or offshore. Moreover, the present invention relates to a vehicle for transporting gas, in particular compressed natural gas.
Patent EA-032039-B1 (EA)
Inventor: ANDINO RAFAEL VICTOR
IPC: A61M5/20
Filed: 2014-05-02
Abstract: Устройство включает в себя корпус, соединенный с контейнером с лекарственным веществом, соединенным с иглой. Инъекционный узел расположен в корпусе и включает в себя энергонакопительный элемент и исполнительный стержень. Дистальный концевой участок исполнительного стержня расположен в контейнере с лекарственным веществом. Энергонакопительный элемент может создавать силу на проксимальном концевом участке исполнительного стержня, достаточную для перемещения дистального концевого участка исполнительного стержня в контейнере с лекарственным веществом. Это может обеспечить перенос по меньшей мере части вещества из контейнера с лекарственным веществом через иглу, когда дистальный кончик иглы расположен в первой области целевого места. Эта сила является недостаточной для перемещения дистального концевого участка исполнительного стержня в контейнере с лекарственным веществом, когда дистальный кончик иглы расположен во второй области целевого места.
Patent EA-034329-B1 (EA)
Title: Method of producing composite nanocoating on nanostructured titanium
Inventor: ZEMTSOVA ELENA GEORGIEVNA
IPC: C23C22/78
Filed: 2017-11-23
Abstract: The invention relates to the field of nanotechnology, in particular, the production of composite biomaterial based on nanostructured titanium, with nanocoating based on organotitanium nanostructures with inclusions of calcium phosphate nanostructures as osseointegration promoters to produce biomaterial of accelerated acceptability in bone tissue while maintaining the strength characteristics of nanotitanium. Technical result of the claimed method is an increase in the rate of engraftment of biomaterial with bone tissue and longer service life of the coating while maintaining high strength properties of the nanotitanium. The technical and economic efficiency of the claimed invention, as shown by the results of biomedical testing, is determined by obtaining medical implants with improved mechanical properties and accelerated engraftment with human bone tissue. This can lead to an improvement in the quality of human life and decrease in the time of rehabilitation after implantation. The new technology for producing composite nanostructured material based on nanostructured titanium with bioactive nanocoating can be used for implants in dentistry, reconstructive surgery and orthopedics.
Patent EA-034930-B1 (EA)
Title: Nasal dilator
Inventor: JOHNSON MICHAEL RALPH BURGESS
IPC: A61F5/08
Filed: 2015-06-05
Abstract: The invention relates to a nasal dilator comprising a body for insertion into a nasal cavity of a nose, the body including a loop structure having an inner surface, a reverse outer surface, a first side and a second side opposite to the first side, wherein the inner surface defines an aperture and the reverse outer surface is configured for urging against a nasal passage wall of the nose; an arm member having a first end coupled to the loop structure and a free end, the arm member extending outwardly from the loop structure and configured to extend along a nasal passage of the nasal cavity and engage with an internal surface of a nostril of the nose; a platform spanning the aperture defined by the inner surface of the loop structure; and a valve mechanism for controlling fluid flow through the aperture. The invention also relates to a nasal dilator device comprising nasal dilators of the above mentioned type coupled together.
Patent EA-034101-B1 (EA)
Title: Method for increasing fuel combustion efficiency and device for carrying out said method
Inventor: VOROBIEV LEONID JURIEVICH
IPC: F02B31/04
Filed: 2015-09-24
Abstract: The invention relates to machine building and can be used in an exhaust system of an internal combustion engine of a moving vehicle and a stationary mechanical drive. A method is proposed for increasing the efficiency of fuel combustion by using a device in which standing waves are created to sustain a vibratory combustion mode by organising the gas flow in the device in the form of two interacting flows, a swirling flow and a central flow, which lead to the creation of standing waves. In order to achieve the result, a device with flat deflection plates (5), is used, said plates being mounted in a guide apparatus (4) at an angle of 35-45º to a central axis (6) in order to create a standing wave with peaks of frequencies corresponding to the natural frequency of the atoms in an oxygen molecule. The technical results of the claimed solution are an increase in the efficiency of fuel combustion and a reduction in the amount of harmful substances discharged into the atmosphere.
Patent EA-036317-B1 (EA)
Title: Method of making a paper product and papermaking machine
Inventor: CHOU HUNG LIANG
IPC: D21H27/38
Filed: 2014-11-14
Abstract: The invention provides a method of making a paper product, the method comprising forming an aqueous cellulosic web on a structuring fabric in a papermaking machine; non-compactively dewatering the cellulosic web on the structuring fabric; and drying the cellulosic web to form the paper product, wherein the portion of the structuring fabric on which the cellulosic web is formed has a planar volumetric index of at least about 26, and an absorbent cellulosic sheet made by this method, and a papermaking machine for implementing this method. Furthermore, embodiments of a method of determining fabric characteristics are provided.
Patent EA-039042-B1 (EA)
Title: Ectonucleotidase inhibitors and methods of use thereof
Inventor: BILLEDEAU ROLAND JOSEPH
Filed: 2017-12-21
Abstract: The invention relates to novel heterocyclic compounds of general formula (I) and pharmaceutical compositions thereof. The invention further relates to methods of inhibiting 5'-nucleotidase in a cell and methods of treating a disease or disorder selected from cancer, cerebral and cardiac ischemic diseases, fibrosis, immune and inflammatory disorders, inflammatory gut motility disorder, neurological, neurodegenerative and CNS disorders and diseases, depression, Parkinson's disease, and sleep disorders using the compounds of the invention.
Patent EA-039426-B1 (EA)
Title: Device for three-dimensional printing of buildings and architectural and construction modules
Inventor: RUBANOV YURY KONSTANTINOVICH
IPC: B29C64/20
Filed: 2020-02-25
Abstract: The invention relates to additive technologies by three-dimensional printing and can be used in construction of buildings, architectural and construction modules from hard construction mixes. The technical result consists in obtaining sturdy buildings and architectural and construction modules from hard construction mixes of complex geometric shape. The technical result is achieved by that a device for three-dimensional printing of buildings and architectural and construction modules includes, installed on a platform which is equipped with a movement mechanism, a device for application of a layer of material, comprising a container for material and a vibrator, as well as a device for filling a given amount of the material, wherein the container for material is made in the form of a transformable element of a discrete additive printing consisting of side and end walls, wherein the side walls are made of a plurality of pivotally connected vertical rectangular plates which are, excluding two central opposite plates, made with the possibility of horizontal mutual movement of the opposite plates while simultaneously rotating relative to a vertical plane by equal adjacent angles providing a given curve profile of walls of a building, the end walls are pivotally connected with horizontal tie rods fixed between end vertical plates in an upper edge with the possibility of providing constant distance between the plates, and equipped with mechanisms of rotation relative to the tie rods by angle of not less than 90°, the vibrator with horizontal propagation of acoustic oscillations is made with the possibility of reciprocal input into the layer of material at each discrete printing cycle, and the platform is made with the possibility of rotation around its axis.
Patent ES-2178565-B1 (ES)
Title: Matriceria de troquelado de sellos en materiales metalicos.
Inventor: MARTINEZ-ROMERO MURCIANO PEDRO
IPC: B26D3/10
Filed: 2000-09-25
Granted: 2004-10-16
Abstract: Matricería de troquelado de sellos en materiales metálicos. Las piezas antagonistas de la matricería (1) de corte a troquel de estas láminas metálicas (2), en cualquier metal o aleación, incluso en metales nobles, preimpresas por offset u otro procedimiento o pregrabadas, definen una diversidad de sellos (3), en configuración geométrica de borde en ondulación (4), con línea de corte a troquel optimizada en ondulación (4) perimetral continua, que evita los picos agudos del corte del sello punzonado, equilibra el acabado del corte en las proximidades de las esquinas (7) del sello (3), en ángulos diversos, definiendo un amplio sector circular (8) de vértice.