baber/WOPTO huggingface dataset:
Patent NZ-571326-A (NZ)
Title: Tetrahydropyridothienopyrimidine compounds and methods of use thereof
Inventor: ZHANG CHENGZHI
IPC: A61K31/519
Filed: 2007-03-20
Abstract: Disclosed are tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-amines as represented by the general formula (I), wherein the substituents are as defined herein. Further disclosed is a composition comprising a compound as defined above together with a pharmaceutically acceptable carrier for the treatment or prevention of a cell proliferative disorder such as cancer.
Patent NZ-572585-A (NZ)
Title: 1,3,4-Oxadiazole derivatives as DGAT1 inhibitors
Inventor: PLOWRIGHT ALLEYN THOMAS
IPC: A61K31/4245
Filed: 2007-05-29
Abstract: Disclosed is an oxadiazole amide derivative of formula (I), or a salt thereof, wherein n is 1-3 and R is selected from fluoro, chloro, cyano, methyl, ethyl, methoxy, ethoxy, trifluoromethyl, trifluoromethoxy and difluoromethoxy. Also disclosed is the use of the compound to treat diabetes mellitus or obesity, or to inhibit DGAT1 activity. Also disclosed is a process for synthesising the compound.
Patent NZ-573993-A (NZ)
Title: A structure for supporting planting growth on a slope using bags of supporting, fertilising, and absorbing medium and fasteners
Inventor: CHANG YUSHUN
IPC: E02D17/20
Filed: 2006-06-01
Abstract: A slope planting structure includes containing bags laid on the surface of a slope, stuffing filled in the containing bags, and fasteners. The stuffing composed of plant growing material and absorbent material is filled into the containing bags. The containing bags are laid on the surface of the slope, and then the fasteners are inserted through the containing bags to secure the containing bags on the slope. A connecting buckle is provided between every two of the containing bags for connecting and securing the containing bags transversally. The containing bags are integrated with the slope to secure the slope for providing protection and greening.
Patent NZ-583451-A (NZ)
Title: 4-[(2-N,N-diethylaminocarbonyl)pyrid-5-yl]-spiro[1,2-dihydronaphthalene-2,4'-piperidine] and methods of its use
Inventor: DOLLE ROLAND E
IPC: A61K31/55
Filed: 2010-02-19
Abstract: Spirocyclic heterocyclic derivatives of the structural formula shown herein, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the spirocyclic heterocyclic derivatives are ligands of the delta opioid receptor and may be useful, inter alia, for treating and/or preventing pain, anxiety, gastrointestinal disorders, and other delta opioid receptor-mediated conditions.
Patent NZ-589864-A (NZ)
Title: Apparatus for mixing and dispensing medicament with energy storage devices, typically plungers, for mixing and dispensing
Inventor: EDWARDS ERIC SHAWN
IPC: G16H40/60
Filed: 2007-03-28
Abstract: A medicament container lies in a housing and has a first energy storage (typically a plunger) to mix volumes for a medicament, and a second energy storage (typically another plunger) to expel the mixed volume medicament. Various embodiments are disclosed.
Patent NZ-590950-A (NZ)
Title: Articles of manufacture releasing an active ingredient
Inventor: THEBERGE KARINE
IPC: A61K9/16
Filed: 2009-07-17
Abstract: The present disclosure relates to articles of manufacture having a formulation distributed therein, wherein the formulation comprises an active agent which manifests a desirable property when released from the articles of manufacture. The present disclosure also relates to methods for manufacturing these articles of manufacture, to vehicles for applying the formulation to these articles of manufacture, and to perception indicators indicating the presence and the amount of formulation comprising an active agent applied to an article of manufacture. Particularly the disclosure is directed to An article for applying an active ingredient to an integument of a subject, comprising: a) a substrate in a substantially dry condition and b) the substrate carrying microparticles, wherein the microparticles include the active ingredient dispersed within a carrier material, the microparticles being responsive to conditions established in proximity to the integument to progressively release the active ingredient for transfer to the integument, to the microparticles and to medical uses of the described articles.
Patent NZ-592809-A (NZ)
Title: SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS
Inventor: HAAS JULIA
IPC: A61K31/519
Filed: 2009-10-21
Abstract: Disclosed herein are pyrazolo[1,5a]pyrimidine compounds of formula II, wherein the substituetns are as defined within the specification, processes for their preparation, compositions comprising said compunds and uses thereof. Said compounds are useful as Trk kinase inhibitors and as such are useful in the treatment of pain, cancer, inflammation, neurodegenerative disease, Typanosoma cruzi infection and osteolytic disease. Preferred compounds include: · (R)-N-(5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxyazetidine-1-carboxamide; · (R)-3-(5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-1,1-dimethylurea; · (R)-1-tert-butyl-3-(5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)urea; · (R)-1-(5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-phenylurea; · (R)-N-(5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)isobutyramide; · (R)-N-(5-(2-(3-fluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-1-methyl-6-oxo-1,6-dihydropyridazine-3-carboxamide; · (R)-N-(5-(4,4-difluoro-2-(3-fluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxyazetidine-1-carboxamide; · (R)-N-(5-(2-(2-chloro-5-fluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxyazetidine-1-carboxamide; · (R)-2-(5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-ylamino)-2-oxoacetic acid.
Patent NZ-599407-A (NZ)
Title: Methods of preparing mesenchymal stem cells, compositions and kit thereof
Inventor: GOLITHADKA UMESH BAIKUNJE
IPC: C12N5/071
Filed: 2010-11-25
Abstract: Disclosed a method of preparing a Master Cell Bank composition comprising Mesenchymal stem cells, Fetal Bovine Serum (FBS) and Dimethyl Sulphoxide (DMSO), said method comprising acts of: a. obtaining and diluting bone marrow cells in culture media and centrifuging the diluted cells to obtain a first pellet and re-diluting the first pellet with the culture media; b. adding density gradient solution to the re-diluted pellet and centrifuging to obtain a buffy layer at interface; c. re-adding equal volume of the culture media to the buffy layer and centrifuging to obtain a second pellet, followed by suspending the second pellet in the culture media and incubating to achieve about 80% to 85% confluency; d. aspirating the culture media and washing the confluent cells with Dulbecco’s Phosphate Buffered Saline (DPBS), thereafter treating the cells with 0.25% trypsin and re-incubating the treated cells; e. neutralizing the re-incubated cells with neutralization media and re- centrifuging the cells to obtain a third pellet, followed by suspending the third pellet in the culture media and freezing the cells with freezing media comprising about 85% to 95% FBS and about 5% to 15% DMSO; and f. trypsinization of the frozen cells and resuspending the trypsinized cells in the freezing media to obtain the Master Cell Bank composition.
Patent NZ-607630-A (NZ)
Title: Transdermal therapeutic systems with crystallization-inhibiting protective film (release liner)
Inventor: BRACHT STEFAN
IPC: C07J7/00
Filed: 2011-09-02
Abstract: This disclosure relates to a solid transdermal therapeutic system (Fig 1) with at least one single-layer matrix which comprises a matrix polymer supersaturated with gestodene or a gestodene ester, and ethinylestradiol, wherein gestodene is present in an amount of 2.1 mg and ethinylestradiol is present in an amount of 0.55 mg, and a removable protective film directly adjacent to the active-ingredient-containing matrix which is a siliconized or fluoropolymer-coated polyester removable film (release liner), the therapeutic system having a layer order starting, furthest removed from the skin, with a backing layer, an adhesive layer, a release layer, the active-ingredient-containing matrix and the removable protective film, and wherein if any fraction of gestodene or gestodene ester not dissolved in the matrix polymer crystallizes out, it crystallizes out in the form of amorphous or crystalline particles with an average diameter of at most 200 μm, at the interface between removable protective film and active-ingredient-containing matrix or in the active-ingredient containing adhesive matrix, and on an area of less than 2% of the interface between the removable protective film and the active-ingredient containing matrix; and the matrix is free from solubility promoters, crystallization inhibitors and dispersants. The transdermal therapeutic system may contain a UV absorber.
Patent NZ-610341-A (NZ)
Title: Drug-eluting self-retaining sutures and methods relating thereto
Inventor: AVELAR RUI
IPC: D02J3/00
Filed: 2011-11-03
Abstract: Disclosed is a suture comprising: a filament; a drug associated with the filament; a plurality of tissue retainers formed in the filament; wherein kinetics of the release of the drug is determined by the distribution of the drug in at least one of the filament and the retainer, wherein the filament includes a plurality of braided suture threads.
Patent NZ-613912-A (NZ)
Title: Carton and carton blank
Inventor: PSALIDAS MARIA
IPC: B65D71/22
Filed: 2012-02-10
Abstract: 613912 A carton for packaging one or more articles (B), includes a series of main panels hinged one to the next to form a tubular structure. The tubular structure includes a top panel, first and second side panels and a base panel and at least one display window struck from at least one of the side panels. The at least one window extends from the top panel to the base panel and is interrupted by a retention strap. Part of window is formed from curved weakened line forming a warped surfaced of side panel.
Patent NZ-614970-A (NZ)
Title: A pharmaceutical composition for treating a disease in the oral cavity comprising rebamipide
Inventor: MATSUDA TAKAKUNI
IPC: A61K31/4704
Filed: 2012-03-22
Abstract: Disclosed is a pharmaceutical composition comprising rebamipide (2-(4-chlorobenzoylamino)-3-[2(IH)-quinolon-4-yl] propionic acid) having a concentration between 10-50 mg/ml rebamipide, a mean particle size of less than 500 nm, a dispersing agent, and a viscosity enhancing agent, wherein the dispersing agent is selected from polyvinylpyrrolidone, hydroxypropylmethylcellulose, polyoxyethylene polyoxy-propylene glycol, or carboxymethylcellulose sodium and the viscosity agent is selected from polyvinylpyrrolidone or pullulan. Also disclosed is the use of the pharmaceutical composition as a gargle or a liquid preparation for swish and swallow for preventing and/or treating stomatitis caused by radiotherapy.
Patent NZ-703459-A (NZ)
Title: Tetrahydropyrazolopyrimidine compounds
Inventor: SATOH TAKASHI
IPC: C07D487/04
Filed: 2013-05-31
Abstract: Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis
Patent NZ-704247-A (NZ)
Title: Compositions and treatment for eye diseases and disorders
Inventor: CHANG WEI-WEI
IPC: A61K31/57
Filed: 2013-07-26
Abstract: The present invention relates to compositions and methods for treating eye diseases and disorders. Specifically, the invention relates to the use of an effective amount of progesterone in the manufacture of a pharmaceutical composition for treating ocular surface diseases or disorders by topical administration of the pharmaceutical composition to the forehead or temple region of a subject.
Patent NZ-706882-A (NZ)
Title: Table game system
Inventor: SHIGETA YASUSHI
IPC: G07F17/32
Filed: 2013-07-08
Abstract: A table game system is provided capable of identifying shuffled playing cards used at the time of the occurrence of a problem in a card shoe apparatus, thereby enabling an investigation of the cause thereof or the taking of countermeasures therefor. A card shoe apparatus 2 of the table game system of the present invention includes a barcode reader 100 that reads a barcode provided in a shuffled playing card set 1s, thereby reading a shuffled card ID that uniquely identifies the shuffled playing card set 1s. Also, a lid for enabling the entry/removal of the shuffled playing card set 1s is provided in an upper portion of the card shoe apparatus 2. A sensor S for detecting the opening/closing of the lid is provided under the lid to detect the opening/closing of the lid, thereby detecting replacement of the shuffled playing card set 1s. A control unit further includes a function of storing the following security items in connection with a shuffled card ID: (1) a reading error of a code C of a card 1 in a cord reading unit (in the case of a false card, the code is not present in the card 1 or a false code is printed on the card 1, and these will be determined as irregular by the card reading unit) and (2) replacement of the shuffled playing card set 1s (such replacement is determined by detecting the opening/closing of the lid).
Patent NZ-711758-A (NZ)
Title: Method for sterilizing drinks contaminated with acetic acid bacteria
Inventor: TAUPP MARCUS
IPC: A23L3/358
Filed: 2015-09-04
Abstract: The invention relates to a method and the use of synergistically acting mixtures comprising a) sorbic acid or benzoic acid and/or alkali metal salts and/or alkaline earth metal salts and b) dimethyl dicarbonate and c) sulphur dioxide and/or sulphur dioxide-releasing substances for sterilizing and subsequent preservation of drinks which have been contaminated with acetic acid bacteria.
Patent NZ-714183-A (NZ)
Title: An apparatus for feeding animals
Inventor: JEFFREY DAVID WRIGHT
IPC: A01K5/01
Filed: 2015-11-13
Abstract: An apparatus for feeding animals is provided. An apparatus for feeding an animal comprising: an elongated shaft having a handle end and a proximal end which has a generally T-shaped member; a substantially triangular central link which is adapted to releasably engage with the proximal end of the shaft by way of an aperture which receives the T-shaped member and also having at least one female connecting member; at least one bowl support which is able to releasably engage with the central link and being adapted such that it has at least one male connecting member which releasably engages with the central link female connecting member; and at least one bowl; the apparatus adapted such that the bowl is able to releasably engage with the at least one bowl support and the apparatus is arranged such that in use a user is able to grasp the handle and lift and carry the apparatus. The apparatus makes it much easier for the elderly or people with physical disabilities to feed their pets.
Patent NZ-718053-A (NZ)
Title: Barbecue grill with multiple burner outputs
Inventor: STEPHEN SPENCER
IPC: A47J37/07
Filed: 2014-02-28
Abstract: A barbecue or a portable cooker, comprising a body 10 that further comprises an oven chamber 12, an oval cooking surface 40 being arranged in the body, a middle burner and two side burners being further arranged in the body. The two side burners are on either side of or smaller than the middle burner. The middle and side burners are located to each provide a heating output for a distinct heat zone.
Patent NZ-731374-A (NZ)
Title: Methods for improving safety of blood-brain barrier transport
Inventor: DENNIS MARK
IPC: C07K16/46
Filed: 2013-05-20
Abstract: The invention relates to the use of an antibody which binds to a transferrin receptor (TfR) in the manufacture of a medicament for transporting a compound across the blood-brain barrier (BBB), wherein the antibody is coupled to the compound, and wherein the antibody has an IC50 for the TfR from about 5 nM to about 100 µM and wherein the antibody comprises an Fc region and the effector function of the antibody Fc region or complement activation function of the antibody has been reduced or eliminated relative to a wild-type antibody of the same isotype such that reduction of red blood cell levels in the subject upon antibody administration is decreased or eliminated.
Patent NZ-732756-A (NZ)
Title: Processes for the preparation of a diarylthiohydantoin compound
Inventor: HAIM CYRIL BEN
IPC: C07D401/04
Filed: 2015-12-17
Abstract: Disclosed are processes and intermediates for the preparation of compound (X), which is currently being investigated for the treatment of prostate cancer.
Patent NZ-738961-A (NZ)
Title: Synergistic fungicidal mixtures and compositions for fungal control
Inventor: OWEN W
IPC: A01N43/54
Filed: 2014-12-30
Abstract: The present invention relates to a synergistic fungicidal mixture comprising a fungicidally effective amount of the compound of Formula I: 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2-(1H)-one, and at least one succinate dehydrogenase inhibitor that provides synergistic control of selected fungi. This invention also relates to synergistic fungal composition containing this mixture.
Patent NZ-740480-A (NZ)
Title: A window fastener
Inventor: TOLLADAY IAIN THOMAS
IPC: E05C17/46
Filed: 2016-09-07
Abstract: A window fastener (1) comprising: a base (2), configured for connection to the moveable sash of a window; a flap (3) pivotally connected to the base (2); wherein the base (2) and flap (3) are configured and connected so that the flap (3) can rotate between a closed position and an open position; the base (2) and flap (3) further configured and connected so that the flap (3) can pivot a substantial angle past the closed position, away from the open position. In the prior art, window fasteners or catches had the disadvantage that if the handle is not rotated sufficiently to allow the flap to rotate fully horizontal, the inner end of the flap can fail to clear the upper edge of the base of the window frame. The present invention provides an improved window fastener or spring to attend to this problem.
Patent NZ-754635-A (NZ)
Title: A process for producing human milk fat substitutes
Inventor: YAEL HERZOG
IPC: A23D9/02
Filed: 2019-06-19
Abstract: The present invention relates to a process for producing a composition comprising a mixture of 1,3‐dioleoyl‐2‐palmitoyl glycerol, 1,3-dilinoleoyl-2-palmitoyl glycerol and 1-oleyl-2-palmitoyl-3-linoleyl glycerol. The process comprises subjecting palm stearin to enzymatic transesterification with free fatty acid mixture using 1,3‐lipase, wherein said free fatty acid mixture contains greater than 25wt.% linoleic acid and greater than 20wt.% and lower than 70wt.% oleic acid; and the ratio between the content of oleic acid in the free fatty acid mixture to the content of linoleic acid in the free fatty acid mixture is greater than 0.5 and lower than 2. The compositions prepared by the process of the invention are suitable for the preparation of infant formulas and baby foods.
Patent NZ-759206-A (NZ)
Title: Surface painting device for rotor core
Inventor: ZHANG HAITING
IPC: H02K15/02
Filed: 2019-11-14
Abstract: The present invention is aimed at providing a surface painting device for a rotor core with high efficiency and good painting effect. The device comprises a feeding mechanism, a painting mechanism and an unloading mechanism, wherein the feeding mechanism at least comprises a collection box; an opening is formed on a front side of the collection box and a rail arranged obliquely is connected to the collection box; the height of the rail gradually decreases from back to front; the painting mechanism at least comprises a paint storage box, a first driving device and two upper rollers; a front end of the rail is located on upper sides of the upper rollers; a rotor moves along the rail to fall between the two upper rollers, and a circumferential surface of a rotor core comes into contact with circumferential surfaces of the upper rollers; the first driving device is used for rotating the upper rollers; the paint storage box is located on lower sides of the upper rollers; and, axes of the two upper rollers are arranged in parallel.
Patent PT-101236-A (PT)
Title: Commercial juice extractor with high reliability - has motor inside housing and connected to extracting cone with micro-switch and cone to position object to be squeezed
Inventor: ZARATE LUIS CARLOS ORTIZ DE
IPC: A47J19/02
Filed: 1993-03-25
Abstract: The extractor comprises an extruded central cylindrical body (I) housing the electric motor (2). The base or stand (4) is formed by a cylindrical plate cupped at its centre to provide a compartment for the wound up supply cable. Two semispherical bodies (16,20) are fitted on to the upper part of the central body (1) with an outlet pipe (18), for the extracted juice being placed under pressure over the lower body (16). The extraction component is composed of a grooved cone (25) on to which a filter (28) is fitted. An upper lever arm )30) is fixed to the central body (1) to facilitate extraction. The arm is articulated at the centre and supplied with a micro-switch (34) and a cone (33) for positioning the product to be squeezed, along with a sealing lid (32).
Patent PT-101754-A (PT)
Inventor: BUELL KENNETH BARCLAY
IPC: A61F/
Filed: 1995-08-09
Abstract: Absorbent articles having a unique elastic waist feature improving dynamic fit as well as containment characteristics. The elastic waist feature preferably comprises an interconnecting panel zone, a first flexural hinge zone joining the interconnecting panel zone with the containment assembly, an elasticized waistband, and a second flexural hinge zone joining the elasticized waistband with the interconnecting panel zone. The elasticized waistband comprises a shaping panel zone; a waistline panel zone; and a predisposed, resilient, waistband flexural hinge zone joining the shaping panel zone and the waistline panel zone. The waistband flexural hinge zone is predisposed to allow the panel zones to flexurally bend about a defined axis or zone is resilient to provide a restoring force/moment that returns the panel zones to their preceding in-use configuration, especially when the elasticized waistband has been pretensioned by a closure system. The closure system dynamically creates/maintains lateral tension through the elasticized waistband thereby allowing the elasticized waistband to more dynamically expand and contract with the motions of the wearer. The absorbent article additionally preferably comprises a pair of elasticized side panels disposed in the second waist region. The elasticized side panels preferably comprise a "zero strain" stretch laminate and an extension panel. The present invention also relates to alternative waist features comprising "an expansive tummy panel" elasticized waistband.