baber/WOPTO huggingface dataset:
Patent CR-20230378-A (CR)
Title: Process for preparing a conjugate linking moiety
Inventor: MAGUIRE ROBERT JOHN
IPC: C12P7/02
Filed: 2022-01-07
Abstract: The present invention relates to processes for preparing linkers that are useful in the conjugation of therapeutic molecules (e.g., cytotoxic agents) with targeting moieties (e.g., proteins, peptides, antibodies, nanoparticles, nucleic acids). During said processes lipases like lipase B from Candida antarctica were used for enantioselective resolution of (S,S)-2-benzylthiocyclohexanol or (S,S)-2-benzylthiocycloheptanol in presence of acylating agent which are reduced for deprotection to yield (S,S)-2-mercaptocyclohexanol or (S,S)-2-mercaptocyclopentanol which can then be used for linking therapeutic with targeting moieties.
Patent EC-SP003840-A (EC)
Title: Biblioteca de sustancias, procedimiento para su preparacion y el suso de esta biblioteca de sustancias para la investigacion de sustancias activas
Inventor: GERLACH MATHIAS
IPC: C07D213/57
Filed: 2000-12-21
Abstract: La invención se refiere a una biblioteca de sustancias, procedimiento para su preparacion y el uso de esta biblioteca de sustancias para la investigación de sustancias activas
Patent EC-SP034861-A (EC)
Title: Formas cristalinas de azitromicina
Inventor: LI ZHENG JANE
IPC: C07H/
Filed: 2003-11-21
Abstract: La presente invención se refiere a las formas cristalinas de azitromicina, un antibiótico útil en el tratamiento de infecciones.
Patent EC-SP045362-A (EC)
Title: Composición pesticida que comprende un éster lactato como inhibidor de crecimiento de cristal
IPC: A01N25/04
Filed: 2004-10-13
Abstract: La presente invención se refiere al campo de las composiciones pesticidas, particularmente al uso de ésteres de ácido lactato como un inhibidor de crecimiento de cristal en dichas composiciones.
Patent EC-SP066342-A (EC)
Title: Sistema de transacciones y pagos mediante teléfono movil digital
Inventor: GARCIA RUANO LUISA
IPC: G06Q20/00
Filed: 2006-02-02
Abstract: Permite el empleo de cualquier tipo de teléfono móvil como medio activador de medios de pago, a través de cualquier red de telefonía móvil(3) de cualquier tecnología de cualquier país conectado al sistema. Comprende una pluralidad de centros procesadores de operaciones y pagos(1) de diferentes países, que están interconectados entre sí mediante procesadores de direccionamiento internacional(2) para realizar transacciones y pagos entre usuarios-pagadores y beneficiarios asociados al sistema seleccionado entre el mismo y diferente país. Los centros (1) tienen una estructura específica para efectuar diferentes tipos de compras, consultas, modificaciones, y autenticación de medios de pago. La invención prevé que los distintos mensajes intercambiados puedan ser hablados. Además la invención permite utilizar un teléfono móvil de un beneficiario como TPV(22),para realizar transacciones.
Patent EC-SP961888-A (EC)
Title: Dispositivo para la sujecion de un componente para fluido
Inventor: EICHER JOACHIM
IPC: B05B1/00
Filed: 1996-10-04
Abstract: La sujeción de un componente que se encuentra bajo la presión de un fluido requiere medidas especilaes, en el caso que el componente consista en un material resistente al desgaste, duro y por tanto generalmente frágil y que puede ser destruido por tensiones localmente incrementadas. Un componente para fluido de este tipo, por ejemplo de silicio/vidrio, se dispone en una pieza moldeada elastómera, por ejemplo de goma de silicona, cuyo contorno está adaptado al contorno externo del componente y al contorno interno de un sujetador. Debido a la "sujeción flotante" no resultan puntas de tensión locales no aceptables ni deformaciones del componente para fluido. El dispositivo es particularmente adecuado para la sujeción de un componente para fluidos que se encuentra bajo alta presión a base de vidrio o silicio en una realización en miniatura.
Patent EC-SP961905-A (EC)
Title: Manufactura de fideos
Inventor: LECHTHALER JUERG
IPC: A21C3/04
Filed: 1996-10-23
Abstract: Proceso para la manufactura de fideos, en el cual se prepara una mezcla de sémola o harina de cereal y agua en una amasadora de tornillos gemelos, la mezcla es convertida en una cinta de pasta para lo cual se la presiona obligándola a pasar a travás de una matriz provista con un orificio de salida oblongo, la cinta es laminada y es cortada en forma de fideos.
Patent FI-19991963-A (FI)
Inventor: PIETILAEINEN ERKKI
IPC: G01N21/78
Filed: 1999-09-16
Abstract: The invention concerns a method for determination of the charge state of filtrate from fibre pulp used in the making of paper and cardboard. In the method, a sample from the fibre is filtered through a filter and an indicator colour is added to the filtrate. The absorbency of the filtrate is measured and the charge state of the solution corresponding to the measured absorbency is read off from the corresponding place on a previously constructed calibration curve. In the first embodiment of the invention, the calibration curve is made by taking a sufficient quantity of samples from the same anionic sample and different quantities of cationic substance are added to these samples so that at least some of the samples become cationic and others anionic. The charge state for the filtered samples is determined in known manner, for example, by cationic titration or potentiometric measurement, after which one measures the absorbencies of the samples corresponding to the charge state of the sample, and draws a calibration curve or constructs a table where a given absorbency corresponds to a given charge state. <IMAGE>
Patent FI-20165686-A (FI)
Inventor: RAKI Olli
IPC: C03B37/029
Filed: 2016-09-14
Abstract: A sealing arrangement for a drawing furnace including a vertical center hole with surrounding heating elements for receiving a glass preform including a tapered portion connected to an extension rod. A sealing with an opening is arranged on top of the furnace. The arrangement includes an outer annular bushing arranged on top of the furnace and an inner annular bushing with a first and an opposing second vertical end. The inner bushing is positionable to surround at least part of the tapered portion with the first end positioned to the region of the beginning of the tapered portion and the second end includes protrusions on the outer surface. As the inner bushing is inserted in the outer bushing it is arranged to be movable within the outer bushing and the protrusions form supports for holding the second end of the inner bushing above the center hole.
Patent GB-1050645-A (GB)
IPC: F42B3/16
Abstract: 1,050,645. Blasting caps. DYNAMIT NOBEL A.G. Feb. 11, 1964 [Feb. 11, 1963], No. 5764/64. Heading F3A. A delay action fuze for a blasting cap comprises a tube 5 of porous sintered metal or plastics containing a delay charge 4 and an initiating charge 3 which is placed adjacent an explosive charge 2 in a copper alloy casing 1. An electric igniter 6 is contained in the casing and has wires 8 passing out through a plug 7-and an aperture 9. Suitable materials for the sintered tube are tin-bronze, copper, chromenickel steel, nickel, polystyrene, vinyl polymers or copolymers, polymethacrylate, polytetrafluorethylene or polyalkalenes.
Patent GB-1051569-A (GB)
IPC: F16J15/14
Abstract: 1,051,569. Connecting pipes to plates &c. TEXTRON Inc. May 25, 1965 [March 25, 1965], No. 22203/65. Heading F2G. [Also in Division F4] A tubular member 12 is joined to an article 22 into which extends a circular, tapered aperture 12 by positioning the correspondingly tapered end of the tube in the aperture and pressing the tube and the article together to cause the tube to engage in the aperture and to distort an adhesive coating 16, which covers the tapered end at least of the tube, into intimate contact with the walls 24 of the aperture. The adhesive, which is of polypropylene and/or epoxy resin and/or urethane cures itself after assembly. Alternatively it may be a plastic material filled with finely divided metal particles and which may be burnt out to leave the metal filler securely bonded in place. Figure 2 shows a construction in which a tube tapered at both ends is used to join the two sections 20 and 21 of a radiator of which the internal spaces are shown in part above and below the tube. A space 26 is allowed to accommodate the flow of adhesive additional to that which extrudes outside at 30a.
Patent GB-1052309-A (GB)
IPC: C07C11/12
Abstract: 1,052,309. Diolefins. BRITISH HYDROCARBON CHEMICALS Ltd. Aug. 10, 1965 [Oct. 20, 1964], No. 42780/64. Heading C5E. Acyclic diolefins are obtained by decomposing a cycloalkane sulphonic acid to a cycloalkene and pyrolysing the latter. The cycloalkene is obtained by the process of Specification 1,022,959. In the preparation of isoprene 1 -methylcyclohexene is preferably separated from other isomers and pyrolysed alone. The decomposition and pyrolysis may be effected simultaneously but preferably sequentially.
Patent GB-1053124-A (GB)
IPC: B41M5/41
Abstract: 1,053,124. Coated paper; coated regenerated cellulose. R. B. RUSSELL. April 15, 1964, No. 15634/64. Heading B2E. [Also in Division G2] A transfer sheet used in thermographic transfer process comprises a support either of paper weighing about 12 pounds per ream of 3000 square feet or of clear regenerated cellulose 1.5 mils thick coated on one side with a dyed heat transferable wax layer and on the other side with eithera wax layer which may contain an infra-red transparent dye, or an infra-red transparent polymeric layer. Specified polymers are regenerated cellulose, carboxymethyl cellulose, cellulose acetate, nylon, polyvinyl acetate, poly-ethylene terephthalate. The dyed wax layer is preferably applied at 5 lbs per ream of 300 square feet.
Patent GB-1053442-A (GB)
IPC: H01L29/73
Abstract: 1,053,442. Semi-conductor devices. MOTOROLA Inc. May 10, 1965 [May 18, 1964], No. 19651/65. Heading H1K. A field effect transistor is produced in a wafer comprising an N-type silicon layer 34<SP>1</SP> epitaxially deposited on a P-type silicon substrate 40, Fig. 4B (not shown), by oxidizing both major faces and selectively etching the oxide layer on the N-type surface to leave a circular region of oxide, Fig. 4D (not shown). Boron is diffused into the wafer to form P-type region 58 which reaches substrate 40 to completely isolate N-type region 34. During this diffusion a layer of borosilicate glass forms over the surface of the wafer. An annular aperture is etched in the masking layer and a second boron diffusion performed to form P-type top gate region 31 which defines the channel 33, the circular drain 30 and the annular source 32. Phosphorous is diffused into the drain and source regions to form N+ type enhancement regions 35, 36. The thin layer of phosphosilicate glass that forms is removed by etching, an annular region of masking layer 48 is removed over gate region 31, and the oxide layer is removed from the lower face of the wafer Fig. 4J (not shown). A layer of aluminium is evaporated on to the top surface and etched to form drain, top gate, and source contacts 25, 26, 27, and a layer of gold 44 is deposited on the lower face of the wafer. A plurality of devices may be produced simultaneously in the same wafer which is then cut into individual dice which are encapsulated by soldering layer 44 to a metal header 14, Fig. 1 (not shown), and thermocompression bonding fine wires to the contacts 26, 27, 25 and to the ends of lead-out wires 16, 17, 18. Wire 16, which is connected by fine wire 21 to the top gate contact 26 is also connected by fine wire 23 to header 14 which makes contact with region 40 part of which operates as the lower gate. The encapsulation is completed by welding cap 11 to header 14. The device is tested and classified according to its parameters. The device may be produced as part of a monolithic integrated circuit. Complementary devices may also be produced, but in these N+ type enhancement regions are unnecessary since the impurity concentration of the gate is sufficiently high for it to be unaffected by the aluminium contact.
Patent GB-1084139-A (GB)
IPC: F41C9/00
Abstract: 1,084,139. Toy cartridges. DE LUXE TOPPER CORPORATION. Feb. 15, 1966 [May 26, 1965], No. 6474/66. Heading F3A. A toy cartridge comprises a shell 20 open at both ends and provided with a rearwardly directed latching shoulder 30 in an aperture 29, a coiled compression spring 21 surrounding a firing pin 22, a bullet 25 provided with a forwardly directed latching shoulder 28 formed on a resilient finger 27 and a post 26, on the bullet Fig. 1 (not shown), adapted to press against one end of the spring to deform the spring into a stressed position when the shoulders are latched together. When the firing pin is moved forwards the outwardly inclined surface 35 co-operates with the surface 36 on the resilient finger and cams the finger radially inwards so as to disengage the latching shoulders and enable the bullet to be propelled forwardly by the spring 21. In a modification a shoulder 49 on a protuberance 48 is disengaged from an annular shoulder 41 on the shell when an elongated stem 47 of the bullet is struck at 50. The bullet 46 is expelled by a tension spring 44. The cartridge is made of moulded plastics and the firing pin is made of metal.
Patent GB-1084246-A (GB)
IPC: B63B27/24
Abstract: 1,084,246. Filling or emptying tanks. WHESSOE Ltd. July 13, 1964 [July 31, 1963], No. 30343/63. Heading B8T. A liquid control system for filling or emptying a series of containers, e.g. tanks in a ship, each of which containers has an inlet/outlet valve V operable by a control switch and by upper and lower limit switches TL, BL, is actuated by the liquid level in the containers, the system being such that each control switch, except the first in sequence, is operated by a limit switch in the preceding container, so that manual operation of the first control switch initiates filling or emptying all the containers. Manual operation of the control switch (not shown) for a first tank to a filling position actuates a relay to open the valve V and as the tank fills a float F actuates a level gauge L to drive cams CT, CB for operating the upper and lower level limit switches TL, BL. When the first tank is full the top limit switch TL opens to de-energize the relay actuating the valve V on the first tank and to energize a similar relay associated with a control switch and valve on the second tank for filling the second tank, the procedure continuing until all tanks are filled. For emptying, the manual switch on the first tank is set to empty and the operation is performed in reverse with the lower level switch BL operating the control switch for the .valve of the subsequent -tank. Several containers may be filled or emptied simultaneously by providing them with a common control switch.
Patent GB-1226233-A (GB)
IPC: F42B7/08
Filed: 1969-02-12
Abstract: 1,226,233. Over-powder wads for shotgun cartridges. P. J. HOWSAM, and J. D. BARTON. 22 Jan., 1970 [12 Feb., 1969], No. 7480/69. Heading F3A. A one-piece, synthetic plastics, over-powder wad for a shotgun cartridge comprises a cylindrical portion 2, Fig. 2, having a terminal recess 6, and a plurality of outwardly diverging leaves 4 defining a shot pouch 7 having a substantially conical outer surface, the leaves being separated by slits 5 and having inclined edges 4a, 4b, Fig. 4, so that the leaves may overlie each other to form a substantially cylindrical outer surface while in the cartridge case and in the barrel of the shotgun. Apertures 3, Fig. 2, in the portion 2 provide a cushioning effect at the time of firing. In another embodiment, Figs. 8 and 9, the cushioning effect is provided by four webs 9, each of which has a weakening 10 to enable rotation as well as longitudinal collapse at the time of firing.
Patent GB-1227685-A (GB)
IPC: F16H7/14
Filed: 1969-06-11
Abstract: 1,227,685. Belt gearing. SANKO SEISAKUSHO CO. Ltd. 11 June, 1969, No. 29513/69. Heading F2Q. A power transmission includes a driven pulley 1 fixed on the shaft 21 of a driven unit 20 (e.g. an air blower) fixed on a bed 17, and driving pulleys 2, 3 each fixed to the shaft 7a, 8a of a drive unit 7, 8 (e.g. an electric motor) mounted on a support 11 having wheels 15, 16 rollable on rails 18, 19 on the bed, one of the drive units 8 being adjustable (e.g. by a bolt 12 threaded at 12a) relative to the support 11, the pulley 1 being connected by belts 4, 5, 6 to the other pulleys 2, 3.
Patent GB-1228164-A (GB)
IPC: H01B7/04
Filed: 1967-03-31
Abstract: 1,228,164. Electric cables. J. W. CRISP, A. WATSON, and A. J. CHABOWSKI. 1 July, 1968 [31 March, 1967], No. 14983/67. Heading H1A. [Also in Division H2] A cable having high voltage cores 1, 2 connected to a source 10 through a circuit-breaker 9, is protected by braided sheaths 4, 7 and an intervening sheath consisting of individually insulated helical wires 5. In one arrangement, Fig. 1, a trip coil 11 is connected via a fuse 12 and low-voltage source 13 to sheaths 5, 7, the sheaths 4, 7 being earthed. In another arrangement, Fig. 2 (not shown), trip coil 11 is connected to source 13 via parallel connected contacts (B1), (Al) of relays (B/1), (A/1) connected between a third source (20) and a pair of wires 5, which may feed an auxiliary load.
Patent GB-1229800-A (GB)
IPC: H01H51/28
Filed: 1967-12-04
Abstract: 1,229,800. Electromagnetic relays; electric selectors; mounting electrical equipment. AUTOMATIC TELEPHONE & ELECTRIC CO. Ltd. 28 Nov., 1968 [4 Dec., 1967], No.55127/67. Headings H1L, H1N and H1R. A cross-point relay matrix of the kind described in Specification 1,146,897 in which interlocking partition members provide a plurality of square section compartments in rows and columns for the reception of reed relays, has external partition members 10 (only one shown) of two parallel sides with at least one lug 12, 14 at each end secured to parallel frame members 18. As shown two pairs 12, 13 and 14, 15 of lugs are provided and self-tapping screws 31 pass through slots 16 to secure the matrix to the frame members 18. Optional members 23 may provide channels such as 28 for cabling. The lugs may be bent into recesses 27 to secure the member 23 to the matrix and the member 23 is then secured by screws (not shown) in holes 30, to the frame members 18.
Patent GB-1230825-A (GB)
IPC: A61G12/00
Filed: 1968-08-08
Abstract: 1,230,825. Latches. ITAL-BED CONSTRUZIONE LETTI E. AFFINI S.R.L. 8 Aug., 1968 [5 April, 1968], No. 37863/68. Heading E2A. [Also in Division A4] Spring-loaded latches 15 are pivotally mounted in a wall panel 5, so as to engage a cross bar 37c of a hospital bed, when it is pushed towards the panel. The latches 15 are lowered to release the cross bar, by depressing pedal 15A. The panel 5 is carried by service ducts (1A), 1B and may support accessories such as a hand rail (19B) and an electric light (22). Occupant retaining guards (51, Figs. 12 and 14, not shown) may also be provided.
Patent GB-1231337-A (GB)
IPC: C08G63/664
Filed: 1969-04-09
Abstract: 1,231,337. Spinning polyester filaments. ASAHI KASEI KOGYO K.K. 9 April, 1969 [9 April, 1968], No. 18087/69. Heading B5B. A method of spinning polyethylene-1,2- diphenoxyethane-p,p<SP>1</SP>-dicarboxylate filaments comprises extruding a melt of polyethylene- 1,2 - diphenoxyethane - p,p<SP>1</SP> - dicarboxylate having an intrinsic viscosity (measured at 35 C. in a solvent consisting of a 2 : 1 mixture by weight of tetrachloroethane and phenol) of from 0À4 to 1À3 and a residual carboxyl group content of not more than 20 eq./10<SP>6</SP> g. and taking up the resultant filaments at a velocity of not more than 3,500 metres per minute. The polyethylene - 1,2 - diphenoxyethane - p,p<SP>1</SP> - dicarboxylate is produced by subjecting 1,2-bis-(paracarbomethoxy)-phenoxyethane or its esterforming derivatives and ethylene glycol to an ester-interchange reaction in the presence of a catalyst A to form the bisglycol ester of 1,2-bis- (paracarbomethoxy)-phenoxyethane and then subjecting the latter to condensation polymerization in the presence of a catalyst B at elevated temperature and reduced pressure while removing excess glycol. Up to 30 mol. per cent of another glycol or dicarboxylic acid may be added in the production of the polyester. Preferred combinations of catalysts A and B are compounds of barium and tin, or barium and antimony, or calcium and antimony, or manganese and germanium. Preferred proportions of A and B are 0À01 to 0À3% and 0À01 to 0À5% by weight of polyester. The melt thus produced is extruded through a spinneret having holes of diameter 0À25 to 0À9 mm. and length 1À5 to 10 mm., the spinning temperature being from 255 to 320 C. The extruded filaments are passed into a zone maintained at a temperature of from 10 to 180 C., which zone extends between the spinneret and take-up point and is from 30 to 2 m. long. The filaments may be rubbed against a friction means in this zone to regulate evenness in denier. The preferred take-up speed is from 1,800 to 3,500 m./min., resulting in filaments having a yield strength of over 1À0 g./d., an initial modulus of elasticity of over 70 g./d., a breaking strength or tenacity of over 3À0 g./d., and aresidual elongation of less than 80%. Lower takeup speeds, e.g. from 1000 to 1800 m./min., may be used for finer filaments, e.g. of denier 0À3 to 1À5.
Patent GB-1238318-A (GB)
IPC: G03C5/58
Filed: 1968-10-02
Abstract: 1,238,318. Silver dispersion. EASTMAN KODAK CO. 2 Oct., 1968 [2 Oct., 1967], No. 46676/68. Heading C1A. [Also in Division G2] A silver nuclei dispersion is prepared by adding (i) 40 ml. of 10% by weight aqueous sodium hydroxide to (ii) 140 ml. of 10% by weight aqueous dextrin and to this mixture adding with stirring (iii) 100 ml. of 10% by weight aqueous AgNO 3  at 40 C. Silver nuclei are produced due to the dextrin induced reduction of AgNO 3  to metallic silver. The electrostatic separation may be effected at 40-80 C. by allowing the ore to fall freely through a field of strength below 2000 V/cm., e.g. 800-1500 V/cm. The ore is thus separated from insoluble impurities, e.g. clay.
Patent GB-1238633-A (GB)
IPC: C22C38/40
Filed: 1969-02-18
Abstract: 1,238,633. Austenitic stainless steel. ALLEGHENY LUDLUM STEEL CORP. Feb.18, 1969 [April 24, 1968], No.8836/69. Heading C7A. An austenitic stainless steel with improved resistance to stress corrosion cracking comprises: - C 0À07-0À1% Cr 15-20% Ni 9-14À5% Si 1À75-2À5% Mn up to 1% Mo less than 0À05% N less than 0À01% and P up to 0À02% the balance, apart from residual impurities, being Fe; and is so proportioned that 100 x %C + 10 x %Si + %Ni - 100 x %N is at least 36.
Patent GB-1252902-A (GB)
IPC: B60B37/10
Filed: 1968-04-26
Abstract: 1,252,902. Securing hubs on spindles. PEDIGREE WESTLINE Ltd. 25 April, 1969 [26 April, 1968], No. 19984/68. Heading F2U. A wheel hub 3 is secured on a spindle 11 by a plastics tongue 10 slidable in a transverse slot 8 in the hub, in one position of which the end of the spindle may be inserted through an opening 13 in the tongue and in a second position a reduced portion 14 of the opening engages a circumferential groove 12 at the end of the spindle to prevent axial separation of the members. The sides of the tongue are formed with spring portions 15 which engage two sets of recesses in the slot to prevent accidental withdrawal of the tongue in either operative position.