baber/WOPTO huggingface dataset:
Patent MX-2016016488-A (MX)
Title: Substituted azetidine derivatives as taar ligands.
Inventor: GUIDO GALLEY
IPC: A61K31/4155
Filed: 2015-08-24
Abstract: The present invention relates to a compound of formula I wherein R1 is hydrogen, methoxy or fluoro; R2/R2' are independently from each other hydrogen, methoxy or fluoro; R3/R4 are independently from each other hydrogen or halogen; R is hydrogen or fluoro; L1 is -CH2-, -NR'-, -0-, -S-, CF2- or CH=; R' is hydrogen or lower alkyl; L2 is a bond, -C(0)NH-, -NH-, -CH2NHC(O)-, -NHC(O)- or -NHC(0)NH-; R is hydrogen, halogen, lower alkoxy, cyano or is phenyl optionally substituted by one or more substituents, selected from halogen, lower alkyl substituted by halogen or lower alkoxy, or is a five or six membered heteroaryl, selected from pyridinyl, pyrimidinyl, pyrazinyl, pyridazinyl or pyrazolyl, which heteroaryls are optionally substituted by one or more substituents, selected from halogen, lower alkyl, lower alkoxy, cyano, cycloalkyl, lower alkyl substituted by halogen, lower alkoxy substituted by halogen or by phenyl substituted by halogen; N is a ring nitrogen atom in position 1 or 2; or to a pharmaceutically suitable acid addition salt thereof. The compounds of formulas I have a good affinity to the trace amine associated receptors (TAARs), especially for TAAR1 and may be used for the treatment of depression, anxiety disorders, bipolar disorder, attention deficit hyperactivity disorder (ADHD), stress-related disorders, psychotic disorders such as schizophrenia, neurological diseases such as Parkinson's disease, neurodegenerative disorders such as Alzheimer's disease, epilepsy, migraine, hypertension, substance abuse and metabolic disorders such as eating disorders, diabetes, diabetic complications, obesity, dyslipidemia, disorders of energy consumption and assimilation, disorders and malfunction of body temperature homeostasis, disorders of sleep and circadian rhythm, and cardiovascular disorders.
Patent MX-2017000383-A (MX)
Title: Automotive windbreaker.
Inventor: FLORENTINO MORENO CASTILLO
IPC: B60J9/04
Filed: 2017-01-05
Abstract: The present disclosure is related to an automotive windbreaker where the driver will have another option to cool off in addition to the air conditioning: a windbreaker. The main function is to introduce air from the outside to the inside, and can be installed on any car door, mainly that of the driver. When the vehicle is moving, the air hits this fin and ends inside the Automobile. The components are three galvanized sills joined by screws, an acrylic sheet, four screws, four pressure nuts and six washers. The first sill is bent to give the same a C shape and in its two final sides are formed folds in the form of a half-closed hand, this is to fasten the same to the edge of the door, and for safety, two holes are drilled where a screw crosses; this screw joins the second sill. The second sill with some folds giving the same an inverted L shape, two holes are drilled, one to insert in the screw of the first sill and the second, to hold the third sill. This third sill, once joined to the second, will be the one that holds the acrylic that has the shape of a half cylinder. The measures of the windbreaker can vary but not its operation nor the assembly procedure.
Patent MX-2017007886-A (MX)
Title: On-demand system for drawing and purifying well water.
Inventor: ANISH MEHTA
IPC: B01D61/02
Filed: 2015-12-16
Abstract: This disclosure provides systems and methods for generating potable water from contaminated water sources, particularly well water. By eliminating the purified water holding tank, employing a combination of source tank with carbon and reverse osmosis filters in series, and using an actuated pump to supply impure water from the source, a simple on-demand system is provided that is especially adapted for use in remote locations. The system and method are particularly useful where only direct current power, such as from a solar photovoltaic panel power, is available.
Patent MX-2017007931-A (MX)
Title: Novel crystal forms of the monosodium salt of foramsulfuron.
Inventor: Martin Krüger
IPC: C07D239/52
Filed: 2015-12-10
Abstract: The present invention relates to a novel crystal form of the monosodium salt of foramsulfuron (formula (I)), a method for producing said crystal form, the use therof in agrochemical preparations as well as certain compositions, mixtures and/or agrochemical preparations containing said crystal form. The invention also relates to a novel monomethanol solvate of the monosodium salt of foramsulfuron.
Patent MX-2017008036-A (MX)
Title: Fungal genome modification systems and methods of use.
Inventor: MICHAEL WARD
IPC: C12N15/80
Filed: 2015-12-16
Abstract: Compositions and methods are provided for genome modification at a target site in the genome of a fungal cell. Aspects of methods and compositions are drawn to a guide polynucleotide/Cas endonuclease system for promoting insertion of a donor DNA at a desired target site in a fungal host cell genome.
Patent MX-2017009614-A (MX)
Title: Vehicle control device and vehicle control method.
Inventor: AKIRA SAWADA
IPC: B60T7/12
Filed: 2015-01-26
Abstract: This vehicle control device for reducing the speed of a vehicle by generating a frictional braking force: detects a speed parameter that is proportional to the traveling speed of the vehicle; detects an accelerator operation amount; estimates a disturbance torque acting on the vehicle; and converges, as the speed parameter decreases, a frictional braking amount to a value that is determined on the basis of the disturbance torque when the accelerator operation amount has become equal to or smaller than a predetermined value, and the vehicle is about to stop.
Patent MX-2017012084-A (MX)
Title: Improvements relating to group messaging.
Inventor: DOEDE DE BOER
IPC: H04L12/58
Filed: 2016-03-22
Abstract: A messaging server (1) improves interworking of the Group-chat feature (such as defined in Rich Communications Services (RCS)) with short message services such as SMS. It matches chat invitations in an effective manner. When an RCS-User invites an SMS-User to an RCS Group-chat session, the identification of the RCS-User in the Group-chat to the SMS-User is via the MSISDN of the RCS-User. Using the MSISDN of the RCS-User in the RCS Group-chat invitation to the SMS-User will provide a direct match with the RCS-User MSISDN in the address-book of the SMS-User and therefore provide immediate clarity from who this Group- chat invitation was received. The SMS-User can accept or reject the Group-chat invitation by returning the proper response as requested in the invitation.
Patent MX-2017015608-A (MX)
Title: Epoxidation process.
Inventor: WOJCIECH L SUCHANEK
IPC: C07D303/04
Filed: 2016-06-02
Abstract: A method is provided for improving the performance of a silver-based epoxidation catalyst comprising a carrier. The carrier includes at least 80 percent alpha alumina and has a pore volume from 0.3 mL/g to 1.2 mL/g, a surface area from 0.3 m2/g to 3.0 m2/g, and a pore architecture that provides at least one of a tortuosity of 7 or less, a constriction of 4 or less and a permeability of 30 mdarcys or greater. A catalytic amount of silver and a promoting amount of one or more promoters is disposed on and/or in said carrier. The method further includes the steps of initiating an epoxidation reaction by reacting a feed gas composition containing ethylene and oxygen present in a ratio of from about 3.5:1 to about 12:1, in the presence of the silver-based epoxidation catalyst at a temperature of about 200°C to about 230°C, and subsequently increasing the temperature either stepwise or continuously.
Patent MX-2018000750-A (MX)
Title: Sand-mold 3d printing device with multiple working boxes.
Inventor: RUI MA
IPC: B33Y30/00
Filed: 2016-08-24
Abstract: A sand-mold 3D printing device with multiple working boxes, comprising: a main frame (100), a working box transport system (200), working boxes (300), a working box lifting mechanism (400), a sanding machine (500), a printing head (600), a cleaning means (700), a liquid material system (800), a sand mixing means (900), and an electric system. The printing device comprises two or more working boxes together with a sand mixing tank, a synchronously operated sanding machine, a through-type printing head, a synchronous working box lifting mechanism, an electric system and so on matching with the working boxes. During sanding and printing operations, the two or more working boxes work synchronously. Compared with a sand-mold 3D printing device with a single working box of the same specification, the printing efficiency of the sand-mold 3D printing device with multiple working boxes is improved by times in equal time, so that the costs of the sand mold are reduced and the production needs are satisfied more quickly.
Patent MX-2018001107-A (MX)
Title: Cleaning and removal of wax deposits in oil and gas wells using cationic polymers.
Inventor: MARCUS FAUST JR
IPC: C11D7/22
Filed: 2016-07-26
Abstract: The present invention generally relates to methods for removing deposits in an oil or gas well by contacting the annular fluid in a batch-wise method with an effective amount of a composition comprising a water-soluble copolymer. These methods are advantageous because they can be used as needed to improve well operation. The methods use a water-soluble copolymer comprised of an acrylamide monomer and one or more cationic monomer.
Patent MX-2018005063-A (MX)
Title: Conditionally active polypeptides.
Inventor: GERHARD FREY
IPC: C07K14/725
Filed: 2016-08-31
Abstract: A non-naturally occurring polypeptide or isolated polypeptide having a ratio of at least 1.3 of an activity in an assay at a first pH in the presence of at least one species having a molecular weight of less than 900 a.m.u. and a pKa up to 4 pH units away from said first pH, to an activity in an assay at a second pH in the presence of the same at least one species. The species has a pKa beween said first pH and said second pH and can be a small molecule. Also disclosed are pharmaceutical formulations including the polypeptide and uses thereof. Methods of producing conditionally active polypeptides are also disclosed.
Patent MX-2018005983-A (MX)
Title: Automatic system and method for delivering a substance to an animal.
Inventor: RAMIN KARIMPOUR
IPC: A61D1/02
Filed: 2016-11-11
Abstract: A system and method for automatically delivering a substance to an animal including a positioning system that positions each animal singularly, a sensor that detects the location of a predetermined targeted area on the animal and an image processor. The system further includes a delivery device having a plurality of delivery outlets for delivering a substance to the targeted area. The sensor, image processor and delivery device are in communication with a computer processor. The sensor activates the image processor which takes at least one image of the animal positioned singularly. The image is communicated to the computer processor and analyzed. The computer processor activates the delivery outlet proximate the predetermined target area on the animal which delivers an effective dosage of substance to the predetermined targeted area.
Patent MX-2018006096-A (MX)
Title: Chimeric cd27 receptors for redirecting t cells to cd70-positive malignancies.
Inventor: GOTTSCHALK STEPHEN M G
IPC: A61K45/06
Filed: 2013-04-26
Abstract: The present invention concerns methods and compositions related to T cells redirected against CD70 for the immunotherapy of CD70-positive malignancies. In aspects of the invention, T cells that are CD70-specific are employed. In particular aspects, there are T cells expressing a novel molecule that comprises the full-length CD70 receptor (CD27) fused to the zeta signaling domain of the T-cell receptor complex. Such T cells recognized CD70- positive tumor cells and have cytolytic activity against CD70-positive cancer cells.
Patent MX-2018006539-A (MX)
Title: Oat-based product and process of manufacture.
Inventor: PIERRE JEAN DUPART
IPC: A23L7/17
Filed: 2016-12-02
Abstract: The invention relates to extruded oat-based products, and their process of manufacture. The invention also relates to compositions which comprise extruded oat-based products, for instance food or beverage compositions.
Patent MX-2018009736-A (MX)
Title: High-strength galvanized steel sheet and method for producing same.
Inventor: KATSUTOSHI TAKASHIMA
IPC: C22C38/00
Filed: 2017-01-30
Abstract: Provided are: a high-strength galvanized steel sheet having exceptional bendability, spot weld crack resistance, stretch-flangeability, and axial crushing stability; and a method for producing the same. This high-strength galvanized steel sheet is provided with a steel sheet and a specific galvanizing layer, the steel sheet having a specific component composition and a steel structure that contains ferrite- and carbide-free bainite in a total area ratio of 25% or less (including 0%), bainite containing tempered martensite and carbide in a total area ratio of 70-97%, martensite and residual austenite in a total area ratio of 3-20%, and residual austenite in an area ratio of 1-5%, the steel structure being configured such that the total area ratio of the ferrite- and carbide-free bainite, the martensite, and the residual austenite is 3-30%, the C level in the residual austenite is 0.10-0.50%, and the average crystal grain size of the carbide-containing bainite and the average crystal grain size of the tempered martensite is 5-20 µm.
Patent MX-2018009872-A (MX)
Title: A roller blind and method of manufacture.
Inventor: YI LIU
IPC: A47H13/00
Filed: 2017-01-20
Abstract: The present invention is related to a roller blind comprising: a length of fabric having a first end connected to a roller tube; a bottom rail have a top piece and a bottom piece releasably secure to one another; a connector for attaching to a second end of the length of fabric; wherein the connector comprises a first retention means adapted to releasably secured to the bottom piece of the bottom rail.
Patent MX-2018011157-A (MX)
Title: Electronic subassembly for a personal care product.
Inventor: JUERGEN BEHRENDT
IPC: B26B21/40
Filed: 2017-03-09
Abstract: An electronic subassembly for a personal care product with a housing defining a chamber. The housing has a tapered guide surface. A first circuit board having a rigid end is positioned within the chamber and a flexible portion positioned outside the chamber. A second circuit board is positioned within the chamber of the housing. The second circuit board has an electrical connector dimensioned to receive the rigid end. An adapter is secured to the first circuit board between the rigid end and the flexible portion. The adapter has a corresponding tapered guide surface that engages the tapered guide surface of the housing to align the rigid end with the electrical connector.
Patent MX-2018012324-A (MX)
Title: Methods for the production and use of myceliated high protein food compositions.
Inventor: BHUPENDRA KUMAR SONI
IPC: A23J1/18
Filed: 2017-04-14
Abstract: Disclosed is a method to prepare a myceliated high-protein food product, which includes culturing a fungi an aqueous media which has a high level of protein, for example at least 20 g protein per 100 g dry weight with excipients, on a dry weight basis. The fungi can include Pleurotus ostreatus, Pleurotus eryngii, Lepista nuda, Hericium erinaceus, Lentinula edodes, Agaricus blazeii, Laetiporus sulfureus and combinations thereof. After culturing, the material is harvested by obtaining the myceliated high protein food product via drying or concentrating. The resultant myceliated high protein food product may have its taste, flavor, or aroma modulated, such as by increasing desirable flavors or tastes such as meaty, savory, umami, popcorn and/or by decreasing undesirable flavors such as bitterness, astringency or beaniness. Deflavoring and/or deodorizing as compared to non-myceliated control materials can also be observed. Also disclosed are myceliated high protein food products.
Patent MX-2018013201-A (MX)
Title: Gas diverter for well and reservoir stimulation.
Inventor: PAUL E MENDELL
IPC: E21B43/16
Filed: 2017-04-05
Abstract: The fracturing methods can provide an advantage over the current fracturing methods. The disclosed fracturing methods can change the fracture gradient of the downhole subterranean formation. For example, one or more of the fracture gradients of the low and high stress zones of the downhole subterranean formation can be changed. Furthermore, the methods of present disclosure, in relation to current practices, can decrease the extent and/or degree of fracturing within low stress downhole formations and increase the degree of fracturing within high stress formations.
Patent MX-2018014306-A (MX)
Title: Article handling device.
Inventor: Robert Scott BOLLINGER
IPC: B25J15/12
Filed: 2017-05-18
Abstract: An article handling device is provided. In one embodiment, a system for article handling is provided. The system has first and second article handling devices that each have one or more gripping assemblies arranged around their periphery. The gripping assemblies are selectably movable between an open position and a closed position based on the relative position of the first and second article handling devices.
Patent MX-2018016054-A (MX)
Title: Methods of treatment using purified (decolorized) aloe vera leaf dry juice.
Inventor: WENJIE LI
IPC: A23L29/275
Filed: 2017-06-15
Abstract: Disclosed herein is a method for improving the health of animal or human microflora using aloe vera. A method of purifying decolorized dried aloe vera leaf juice is also disclosed. The method may include removing an aloe vera leaf from an aloe vera plant, washing and/or sanitizing the leaf, and grinding the leaf into a slurry and subsequently purifying with activated carbon. The method may remove pigmented substances including the undesirable phenolic compounds present in aloe vera latex, and in particular the anthrones aloin A and aloin B, aloesin (a chromone) and aloe-emodin (an anthraquinone). Following purification, the liquid juice may then be spray-dried to form a final dry juice powder.
Patent MX-2019011493-A (MX)
Title: Palm activated drug delivery device.
Inventor: PETER KRULEVITCH
IPC: A61M5/32
Filed: 2012-04-16
Abstract: Disclosed is a device for the parenteral delivery of a medication, such as a drug. The device includes upper and lower housings in which the upper housing is configured to move relative to the lower housing as a result of application of an external force to permit the user of the device to control the rate at which the drug is administered.
Patent MX-2019014113-A (MX)
Title: Combined therapy for nmdar antagonist-responsive neuropsychiatric disorders.
Inventor: JAVITT DANIEL C
IPC: A61K31/42
Filed: 2018-05-24
Abstract: Described herein are compositions, including an oral dosage regimen, for the treatment of NMDAR-related neuropsychiatric disorders such as depression and obsessive-compulsive disorder and that includes an NMDAR antagonist, such as D-cycloserine formulated to produce plasma levels in excess of 25 microgram/mL, combined with more recently developed
Patent MX-2020000493-A (MX)
Title: Absorbent composites.
Inventor: LEI WANG
IPC: A61F13/511
Filed: 2018-07-18
Abstract: Absorbent composites are provided that include a nonwoven top layer having hydrophilic fibers and an absorbent core layer directly or indirectly attached to the nonwoven top layer, wherein the absorbent core layer comprises a through-air-bonded nonwoven. The absorbent composites may include a combination of (i) a composite-run-off value of less than 50% as determined by ISO 9073-11, (ii) a composite-absorption capacity of at least 600% as determined by ISO 9073, and (iii) a composite-rate of absorption of less than 10 seconds for a 5 ml liquid sample as determined by D824-94. The absorbent composites may include an optional film layer attached to the absorbent core layer.
Patent MX-2020001319-A (MX)
Title: Modulation of heparin-binding epidermal growth factor activity for tympanic membrane healing.
Inventor: PETER LUKE SANTA MARIA
IPC: A61K38/18
Filed: 2015-11-13
Abstract: Compositions arid methods are provided for the generation or treatment of chronic tympanic membrane perforation by modulation of HB-EGF activity. In the methods of the invention, a chronically perforated tympanic membrane is topically contacted with an effective dose of heparin binding-epidermal growth factor, HB-EGF, or an agent having HB-EGF activity, for a period of time sufficient to provide for improved healing of the membrane perforation. In some embodiments the dose of HBEGF is provided in a sustained release formulation; in other embodiments regular administration of a non-sustained release formulation is provided. In some embodiments, a sustained release formulation is biodegradable. In other embodiments sustained release is provided by a device, e.g. a pump or other release device.
Patent MX-2020007193-A (MX)
Title: Maternal supplement.
Inventor: AFFOLTER MICHAEL
IPC: A61K33/30
Filed: 2018-11-29
Abstract: A maternal composition wherein said maternal composition is specifically formulated for a woman who has given birth prematurely or who is at risk of giving birth prematurely.
Patent MX-2020007631-A (MX)
Title: Compositions containing combinations of nitrogen-fixing bacteria and additional agents and their use in fixing nitrogen in plant species.
Inventor: AVIDOV AMIT
IPC: C12R1/41
Filed: 2019-01-21
Abstract: The present invention provides a method for supplying the nitrogen requirements of a plant comprising administering to said plant a combination of non-pathogenic, atmospheric nitrogen-fixing bacteria and one or more activating agents. Many of these activating agents possess potent anti-inflammatory and anti-microbial activity. The method is particularly suitable for use in enabling nitrogen fixation in plant species such as wheat, maize and other cereal crops, in which nitrogen fixation is normally not possible. The invention also provides compositions comprising nitrogen-fixing bacteria and suitable activating agents. In one preferred embodiment, the nitrogen fixing bacteria are of the<i> Rhizobium</i> genus.
Patent MX-2020009247-A (MX)
Title: Dual equipment and vacuum impregnation method.
Inventor: JUAN MATEO GARCIA SANCHEZ
IPC: B01J8/00
Filed: 2020-08-18
Abstract: The present invention relates to a vacuum impregnation system, including dual-function equipment of a cylindrical stainless-steel body for storing a volume of 40 liters with a tori spherical lid composed of six rings that help hermetically seal the container, coupled to a vacuum pump. Said equipment operates by the vacuum impregnation method, being an emerging technology that consists of a procedure used to incorporate compounds dissolved in the impregnation solution into a porous solid, submerged therein, and inserted into a perfectly sealed equipment. The said process reduces the pressure, extracts the air, and eliminates humidity, making the solid porous when returning to the atmospheric pressure. Said compounds take the place of the extracted water and air molecules, sterilizing the impregnated material if necessary.
Patent MX-2020009285-A (MX)
Title: Enhanced safety and reliability for a networked detonator blasting system.
Inventor: TEOWEE GIMTONG
IPC: G05B13/02
Filed: 2019-03-07
Abstract: Ethernet systems, methods and blasting machines are presented for remote turn on of the blasting machine and reliable fire and arm commands issuance. Systems, methods, blasting machines and wireless bridge units are presented for wireless blasting for safe firing of detonators under control of a remote wireless master controller in which the blasting machine is connected by cabling to the wireless bridge unit and power to a firing circuit of the blasting machine is remotely controlled via the bridge unit. The bridge unit or Ethernet primary controller selectively provides first and second firing messages to the blasting machine contingent upon acknowledgment of safe receipt of the first firing message by the blasting machine, and the blasting machine fires the connected detonators only if the first and second firing messages are correctly received from the bridge unit.