baber/WOPTO huggingface dataset:
Patent SE-7902660-A (SE)
Inventor: OHRNELL G
IPC: H02J9/02
Filed: 1979-03-23
Abstract: An emergency power circuit is designed in event of power outage to connect a battery 1 to an emergency light source 2. The battery can be connected via a connection device 3 either to a charging circuit 5, 6, 7 which is energised from a power supply network or to the emergency light source. The connection device is arranged so that, during normal power supply, it maintains the battery connected to the charging circuit. According to the invention, a time connection circuit 9 is connected to the connection device and contains at least two time control circuits 10, 11, designed to put out pulses in sequence with different pulse periods. The pulses, in turn, control a transistor 12 which interrupts the power supply to a relay 8, whereupon the charging circuit is disconnected and the battery is connected to the emergency light source. This connection is maintained for a certain determined time corresponding to a first pulse time, after which a new pulse controls the transistor so that the battery is again connected to the charging circuit and is kept in this connection for a time corresponding to a second pulse period. In this way, one has a fully automated connection of the battery to the emergency light source, which must be done with a certain determined time interval in order for the battery to retain its charge capacity. <IMAGE>
Patent TR-22192-A (TR)
IPC: C01B25/41
Filed: 1985-06-07
Abstract: Solid, free-flowing, essentially nonfriable powdery detergent particulates of recrystallized sodium tripolyphosphate hexahydrate having high absorption capacity and a pore volume of at least 0.70 cm3/g, at lest 80% of the intercrystalline porosity thereof comprising pore sizes ranging from 0.5  mu m to 30  mu m, are prepared by (i) spraying water or an aqueous medium over a first fraction of anhydrous sodium tripolyphosphate, the majority of which fraction comprises phase 1 tripolyphosphate, (ii) spraying water or an aqueous medium over a separate second fraction of anhydrous sodium tripolyphosphate, which second fraction essentially consists of phase 2 triplyphosphate, (iii) intimately admixing said first and said second sprayed fractions, (iv) suspending the resulting admixture in water or an aqueous medium, and then (v) drying the resulting suspension, e.g., by atomization.
Patent BG-100641-A (BG)
Title: In ovo vaccination against coccidiosis
Inventor: EVANS NIGEL A
IPC: A61K35/00
Filed: 1996-06-05
Abstract: The method of domestic poultry vaccination against coccidiosis consists in the administration of an effective immunization dose of live Eimeria sporocysts or oocysts or mixtures thereof in the egg.
Patent BG-101296-A (BG)
Title: Structure for excavation reinforcement
Inventor: KRINGS JOSEF
IPC: E02D17/08
Filed: 1997-03-07
Abstract: The structure consists of a basic box (3) of reinforcing slabs (5) supported at some distance by means of braces (8) having a front edge (7) at their upper skirting, and a knife-edge support (6) on their lower skirting, and at least one of the tiers of the supporting slabs (5) of one superstructural box (4) of supporting slabs (5) coaxially positioned on the basic box, which slabs are shaped and aligned like the supporting slabs of the basic box. It is recommendable that connection devices should be designed on the line of impact of the supporting slabs lying one on top of the other thus forming a modular system consisting only of basic slabs, or basic boxes, respectively, and connecting components.
Patent BG-101297-A (BG)
Title: Supporting plate
Inventor: KRINGS JOSEF
IPC: E02D17/08
Filed: 1997-03-07
Abstract: The supporting plate is used in making formworks of excavations in underground works as part of a supporting box or when reinforcement is made with smooth bars. It is convenient for assembly and stable in folding. The plate (13) contains a triangular hollow profile (9) on the lower edge of its knife-type support (12) in which a solid steel ring (18) is inserted for the suspension having a straight part (21) and a rounded part (20) of the outer perimeter the axial external contour of which matches the surface of roofing sheet steel surrounding the ring (18). The straight part (21) forms part of the edge of the "knife" support (12) and the rounded part (20) is welded to the bordering parts of the hollow profile (9).
Patent BG-101610-A (BG)
Title: Refrigeration panel with counterimpact protection
Inventor: ALEKSANDROV JANCHO TS
Filed: 1997-06-12
Abstract: The panel shall find application in civil engineering, e.g.in fruit and vegetable storages. Its structure is protected fromthe impacts caused by the root crops. A heat insulation U-shapedcomponent (3) with elastic spheres (4) is fitted in the panel,between the outer layer (1) in each recess (18) of the innertrapeze-like layer (10). Profile (3) runs along the whole width ofthe panel and by its open side is facing recesses (18). Betweenlayer (1), elastic layer (10) and two adjacent components (3) aheat insulation layer (2) is fitted. An elastic layer (5) isfitted along the whole length of the panel between components (3),layer (2) and the inner trapeze-like layer (10). The inner layer(10) is protected by an elastically formed body (15) which isconnected to elastic spheres (7 & 4) by means of a flexibleconnection part (6). Sphere (7) is fitted between the recesses(18) of layer (10) and the cylindrical part (8) of body (15).1 claim, 5 figures
Patent BG-103550-A (BG)
Title: Double embossed sheet
Inventor: DONA MARINUS J
IPC: B29C33/42
Filed: 1999-07-05
Abstract: The sheet is transparent and is suppled with two-side lenticular row (4). The relief (7) of at least one of the rows (7) has cross section having at least two bends (11-14) thus improving the visibility of the Moire model formed by the two rows. The sheet can be used as a sign for avoiding any fakes. 13 claims, 4 figures
Patent BG-103754-A (BG)
Title: Substituted 4-arylmethylene-2-imino-2,3-dihydrothiazoles, their derivatives and application in the pharmaceutical industry
Inventor: CHEETHAM SHARON C
IPC: C07D417/12
Filed: 1999-09-24
Abstract: The compounds, including their pharmaceutically acceptable salts in the form of individual enantiomers, racemates and other enantiomer mixtures have the general formula where Ar is phenyl, naphthyl or benzo(b)thiophenyl each of which can optionally be substituted; R1 & R2 can be the same or different meaning individually H, alkyl group with 1 to 6 carbon atoms, alkenyl group with 3 to 6 carbon atoms, cycloalkyl group with 3 to 7 carbon atoms, cycloalkylmethyl group the ring of which is with 3 to 7 carbon atoms, aryl or heteroaryl group,  optionally substituted, arylalkyl or heteroarylalkyl group, optionally substituted, or R1 and R2 form alkylene chain optionally substituted with one or more alkyl group with 1 to 3 carbon atoms so that together with the atoms to which they are adjuncted can form 5- or 6-member ring, R3 is H, aryl or heteroaryl group, optionally substituted, arylmethyl group optionally substituted, or alkoxyalkyl group with 3 to 6 carbon atoms, and R4 & R5 can be the same or different and individually mean alkyl group with 1 to 3 carbon atoms, and R4 & R5 together with the atom to which they are adjuncted, form cycloalkyl ring containing 3 to 6 carbon atoms. The invention also relates to a method for the preparation of the above compounds, to compositions containing them and to their application for the treatment of depression, anxiety, Parkinson, neurological disease and as a neuroprotective means. 17 claims
Patent BG-113024-A (BG)
Title: Device for non-invasive electrical stimulation of the endorphinergic center of the brain in human and animals
Inventor: ARNAUDSKI NIKOLAY
IPC: A61N1/32
Filed: 2019-11-08
Abstract: The invention relates to a device for non-invasive electrical stimulation of the endorphinergic center of the human and animal brain and finds application in the field of human and veterinary medicine. The device consists of a power supply unit (1) which is connected on the one side to a low voltage power supply unit (2), on the other side to a control circuit board (3) and an external communication unit(4). The low voltage power supply unit (2) is connected via a main board (5) to a main processor (6) to which is connected a quartz resonator (7). The main processor (6) is connected via a digital-to-analog converter (8) and an analog-to-digital converter (9) to a current generator (10) with leads to electrodes(11). The control board (3) comprises a processor (12) which is connected to the main processor(6) via an optron(13) which is connected to the current generator (10), a touch-screen display (15) and an external communication unit(4) via a second optron(14) . The device, by means of an external communication unit (4) has remote access for control and communication via the Internet, mobile operator or other type of wired or wireless communication. The device uses an electric current with different characteristics in the frequency range from 60 Hz to 90 Hz for different stimulations with quasi-resonant frequencies with options for variations.
Patent CN-1316873-A (CN)
Title: 柔性印刷基板
Inventor: KENMEI KUTO
IPC: H05K1/03
Filed: 2000-12-20
Abstract: 本发明提供一种柔性印刷基板，该柔性印刷基板具有对于金属箔有良好粘结强度的聚酰亚胺层，而且在金属箔浸蚀前后不发生卷曲。本发明使用在金属箔上将聚酰胺酸清漆成膜、酰亚胺化形成聚酰亚胺层的柔性印刷基板，作为聚酰亚胺层，显示有10－30×10 －6 (1/K)的线性膨胀系数，而且显示至少酰亚胺化温度的软化点。
Patent CN-1407185-A (CN)
Title: 离散凸起透水管
Inventor: LI LANYING
IPC: E02D19/20
Filed: 2001-09-13
Abstract: 本发明公开了一种离散凸起透水管，包括渗透过滤层和带孔或缝的透水管，其特征在于所述带孔或缝透水管上设有离散状凸起，离散状凸起之间形成流水通道。本发明优点是透水率高、排水效率高。广泛应用于土壤地下排水，结构体的渗水排除等。
Patent CN-1404062-A (CN)
Title: 盒式盘
Inventor: GYOCHAN CHON
IPC: G11B23/03
Filed: 2001-12-31
Abstract: 本发明提供了一种盒式盘，该盒式盘包括有用于容纳盘的壳体，设置在壳体上的透明窗口，以便于外部光线能够对壳体中的盘进行访问。在该盒式盘中，光线经过设置在盒式盘一侧面上的封闭透明窗口对盘进行访问。这样，就能够防止诸如灰尘这样的外界物质进入到盒式盘中。
Patent CN-1449570-A (CN)
Title: 电阻器及其制造方法
Inventor: TOSHIKI MATSUKAWA
IPC: H01C17/28
Filed: 2001-08-30
Abstract: 提供一种电阻器，可提高上面电极与端面电极电连接的可靠性及提高第一薄膜与第二薄膜的贴附力，能提高可靠性。在基板的一个主面上形成的上面电极由第一上面电极层和重叠在该第一上面电极层上的贴附层构成，同时设置在所述基板的边缘并与所述一对上面电极电连接的端面电极由位于基板边缘的第一薄膜和由Cu系合金薄膜构成的与该第一薄膜电连接的第二薄膜和由镍镀层构成的覆盖所述第二薄膜的第一镀膜和覆盖所述第一镀膜的第二镀膜构成。
Patent CN-1454059-A (CN)
Title: 新型醋海藻粉末或颗粒及其制造方法
Inventor: YOSHIHIDE HAGIWARA
IPC: A23L17/00
Filed: 2001-09-11
Abstract: 本发明提供了含有丰富的易吸收状态的海藻矿物质和食物纤维的深受喜爱的醋海藻粉或颗粒及其制造方法。
Patent CN-1471699-A (CN)
Inventor: GEORGE EDWARD VICTOR
IPC: H01J11/18
Filed: 2001-10-26
Abstract: 本发明公开了一种改进的发光板，该发光板具有夹在两个衬底(10，20)之间的多种微量组分(40)。每种微量组分(40)包含能电离的气体或气体混合物(45)，这时将足够大的电压通过至少两个电极施加到微量组分(40)中。本发明也公开了一种改进的微量组分的激励方法。
Patent CN-1405777-A (CN)
Title: 多位磁存储单元
Inventor: NICOR J H
IPC: G11C11/14
Filed: 2002-08-09
Abstract: 一种磁存储单元(10)包括串连的第一和第二磁阻器件(12，14)。第一和第二磁阻器件(12，14)具有不同的矫顽磁力(L1，L2)的第一和第二传感层(18，14)。磁随机存取存储器(MRAM)器件(812)可以包括这些存储单元(10)的阵列。
Patent CN-1461542-A (CN)
Title: 同步检测装置
Inventor: HIROSHI AZAKAMI
IPC: H04L7/06
Filed: 2002-04-05
Abstract: 在输入信号DT中含有以ATSC标准为基准的段同步信号。时钟信号倍频部111对时钟信号CK进行倍频。切换型采样部112从以倍频后的时钟信号定义的若干时刻中选择采样点，在选择的采样点对输入信号DT进行采样。又，切换型采样部112在同步非确立状态的期间可切换采样点。同步检测装置，在段同步确立后，在场同步检测失败前能维持同步确立状态，根据输入信号的位错误率RT，能在时间方向上对同步检测信号进行移位输出。
Patent CN-1530910-A (CN)
Inventor: DU ZHIBIN
IPC: G09G3/28
Filed: 2003-03-13
Abstract: 一种等离子显示板的驱动方法，于奇半帧选取奇数行的显示单元，并使其放电发光，而于偶半帧中，则选取偶数行的显示单元，并使其放电发光。由于本发明所使用的等离子显示板的显示单元为三角排列式，也就是位于奇数行与偶数行的相邻的不同颜色的显示单元呈交错排列。如此，画面闪动的问题将有效地被改善，而提高画面的品质。此外，由于不同行的显示单元分别由不同的共同电极来控制，故本发明更具有减少交越干扰的优点。
Patent CN-1692473-A (CN)
Inventor: VERONIKA POLEI
IPC: H01L27/115
Filed: 2003-01-27
Abstract: 存储单元系包括于一半导体材质中的一源极区域(1)以及一漏极区域(2)，以及，于该源极以及漏极区域之间所提供的一沟道区域(3)之上，一具有一储存层(D’)位于边界层(A、C)之间的三层层结构以及位于该三层层结构之上的一栅极电极(G)，并且，在该沟道区域之上，该储存层(D’)系被由Al 2 O 3 所制成的一蚀刻层(B’)所取代。在制造期间，该蚀刻层(B’)系被侧向地蚀刻出来，因此，该第二边界层(C)系受到底切，而所形成之空隙则是由该储存层(D’)之该材质(D)所填满，再者，提供适当的间隙壁则是使得该存储单元的尺寸可以加以定义。
Patent CN-1649863-A (CN)
Inventor: NEWCOMBE NICHOLAS J
IPC: A61P1/16
Filed: 2003-03-06
Abstract: 本发明描述了式(I)化合物及药学上可接受的盐和在体内可水解的酯，其中R 1 、R 2 、R 3 、R 4 、R 5 和p如本发明说明书中定义。本发明也描述了所述化合物的制备方法及其作为药物的用途，尤其是作为用于在温血动物如人体内产生细胞周期抑制(抗细胞增殖)作用的药物的用途。
Patent CN-1668441-A (CN)
Inventor: JINGYI XU
IPC: B29C48/395
Filed: 2003-07-17
Abstract: 这项发明提供一种包括低L∶D比的螺杆(14a)的注塑成形和吹塑成形系统(10a)。这个系统能够生产微孔聚合物材料。在某些情况下，这个系统可以通过改造传统的聚合物加工系统形成。改造可能涉及改变(例如，机械加工或更换)传统系统已有的零部件和把新的零部件添加到系统中。例如，改造通常涉及用为满足加工微孔材料所需要的条件设计的新螺杆替换传统的聚合物加工螺杆。在其它的情况下，这些系统可能是新制造的。本发明的改造的或新制造的系统与新制造的L∶D比比较高的微孔加工系统相比是相当便宜的。
Patent CN-86106540-A (CN)
IPC: H01H33/662
Filed: 1986-10-14
Abstract: 一种真空断路器行一体的钟形金属端部件，在一个圆柱形陶瓷套的相对两端上钎焊。端部件圆柱形壁的一部分，在与套接触的交接面附近，厚度减薄。钎焊时减薄部分变形，以减少刚性一体端部件的可能造成密封壳断裂的接触面里的应力。
Patent CN-87102273-A (CN)
Title: 内燃机的控制系统
IPC: F02D41/04
Filed: 1987-03-26
Abstract: 本发明是一种内燃机控制系统，其中喷油量根据加速器踏板的下压量确定，进气量根据喷油量决定。喷油量和进气量的变化由加速器踏板的下压量变化率来校正。
Patent CN-1032505-A (CN)
Title: 双辊式连铸机
Inventor: HIRATA ATSUSHI
IPC: B22D11/06
Filed: 1988-09-21
Abstract: 水口砖中形成通道的部分(中间包中的高温熔体
通过该通道流入熔池)用硬质耐火材料制造，以防止
形成通道的部分熔化。浸入熔池中的水口砖的底部
用具有很好的隔热性的透气耐火材料制造，因此，即
使在不预热水口砖的情况下，基本上也能防止水口砖
吸收熔池中熔体的热量，并且能避免水口砖的底部凝
固壳的生长。
Patent CN-1054215-A (CN)
Inventor: GUOSHI JIANG
IPC: B32B27/10
Filed: 1991-01-28
Abstract: 可挠复合装饰层压板，属家具及室内装饰用板。
采用改性三聚氰胺浸渍表层纸及装饰纸，用乙烯系热
塑性树脂浸渍无纺布底层，经干燥热压而成，成本低，
韧性好，弯曲半径达19mm以上，可用于平面及曲面
装饰，用纸量少，最小厚度达0.25mm，背面不需砂
毛，易于与其它人造板粘贴，制造工艺简单，无污染，
层间不残留有毒物，是一种价廉、美观、耐磨、耐烫、耐
干燥、耐化学药品污染，具优良装饰性能的装饰板。
Patent CN-1068302-A (CN)
Inventor: ZHENHUA CHEN
IPC: B62D57/024
Filed: 1992-05-16
Abstract: 本发明提供的是一种全方位壁面行走机构，突破
了传统技术，采用一只电机三条传动链以实现伸缩，
升降和旋转的运动，并采用的4层框架式和两组8只
固定吸盘结构，具有较好的负重能力和越障能力，还
具有全方位转向功能以及方位校正功能，使得机构能
正确地向任意确定的方向行走，从而能很好地应用在
许多极限条件的场合，如高楼外侧墙窗的擦洗、喷涂，
以及救护、检测等。
Patent CN-1097080-A (CN)
Title: 用于熔碳燃料电池的填质及其制造方法
Inventor: KWEON HO-JIN
IPC: H01M8/02
Filed: 1994-04-08
Abstract: 用于熔碳燃料电池的填质的制造方法，包括用氨

气饱和γ-铝酸锂并加金属钠的步骤，它可在低温下

制作大直径的γ-铝酸锂颗粒。该填质以直径为

4-10μm的γ-铝酸锂颗粒作为主要成分并具有高强

度。
Patent CN-1156641-A (CN)
Title: 烃类制合成气用催化剂的制备方法
Inventor: CHENG JIYUAN
IPC: C01B3/38
Filed: 1996-12-30
Abstract: 本发明是一种烃类制合成气用催化剂的制备方法，采用α-Al 2 O 3 、MgO、CaCO 3 (或RE 2 O 3 ，重稀土氧化物)为原料，经混合、成型、煅烧得载体，然后将其浸渍、焙烧，制得催化剂。本发明所得催化剂特别适用于在低水碳比、低氧碳比条件下，高温转化制合成气或还原气的反应过程，具有良好的抗高温氧化和抗积炭性能，转化活性高，强度高，寿命长。
Patent CN-1178244-A (CN)
Inventor: FANG JIMING
IPC: C12N15/06
Filed: 1996-09-27
Abstract: 本发明是利用生物工程的方法,通过基因工程技 术构建了一种有双重放大功能的表达载体,并获得一株高效表 达的CHO工程细胞。经微载体和低血清培基高密度灌流培养 和纯化,制备一种治疗冠状动脉梗塞,脑血栓,中央视网膜动静脉 血栓和其他血栓病的药物一重组人糖基化尿激酶原。
Patent CN-1155968-A (CN)
Title: 印刷电路板
Inventor: MOTOO ASAI
IPC: H05K1/11
Filed: 1996-06-06
Abstract: 适于用焊料凸点对电子零部件进行可靠的高密度安装和可靠电连接的印刷电路板。印刷电路板的安装表面上形成由焊料光刻胶掩模覆盖的焊盘和焊料凸点。焊料凸点位置与通孔位置一致，或使焊料光刻胶掩模的开口直径大于通孔焊区直径，使焊料光刻胶掩模不覆盖通孔。
Patent CN-1197664-A (CN)
Title: 鼠尾草提取物在制备用于治疗杜普伊特伦挛缩之药物中的应用
Inventor: REINHARD MAX
IPC: A61K36/53
Filed: 1998-04-28
Abstract: 描述了鼠尾草提取物在制备用于治疗杜普伊特伦挛缩之药物中的应用,所述提取物特别是从其花中得到的。
Patent CN-1224318-A (CN)
Title: 具有备用基站和卫星站的蜂窝网络
Inventor: AGRAWAL PRATHIMA
IPC: H04W84/02
Filed: 1998-10-13
Abstract: 蜂窝网络包括控制站和一个基站网络,每个小区安装一个基站,一个或多个移动站能在它们漫游通过小区时与基站通信。冗余布署的备用基站与主基站一起引入每个小区的中心区域,冗余布署的备用基站在有关的主基站过载时处理新呼叫、参与由于恶化的信道条件与网络中的拥塞而丢失的数据的重发并辅助越区切换。主卫星站和备用卫星站布署在以山丘或山谷为特征的区域中以扩大主基站与备用基站的通信能力。
Patent CN-1217650-A (CN)
Title: 包括聚(环氧乙烷)和聚乙烯吡咯烷酮的后发泡剃须凝胶
Inventor: SZYMCZAK T J
IPC: A61Q9/02
Filed: 1998-01-30
Abstract: 一种用作后发泡剃须凝胶的组合物,例如包括约3%至约20wt%的表面活性剂体系、总量约0.05%至约10wt%的聚(环氧乙烷)和聚乙烯吡咯烷酮,其中存在的聚(环氧乙烷)与聚乙烯吡咯烷酮的重量比为约1∶10至约10∶1,和约0.1%至约10wt%的后发泡剂(按组合物计)。
Patent CN-1250237-A (CN)
Title: 无线电话的天线
Inventor: YOSHIMI EGASHIRA
IPC: H01Q1/22
Filed: 1999-07-27
Abstract: 这里提供了一种用于无线电话的天线,其中,在棒状天线从无线电话的机壳伸出的状态下,人体的影响是可忽略的,并且可以以接近水平方向的角度发射无线电波,而在棒状天线收回到机壳内的状态下,不会产生不需要的辐射。为了这个目的,电长度为λ/4的螺旋天线20和可通过螺旋天线20的中空部分相对于机壳拉出或收回、电长度为3λ/8并具有感抗的棒状天线10通过一个静电耦合部分30电耦合,其中静电耦合部分30具有在棒状天线10从机壳50伸出的状态下抵偿棒状天线10的感抗的容抗。连接部件12的底部12a的长度被设置为这样一种长度,即使得当棒状天线10收回在机壳50内时,连接部件12的底部12a在其整个长度上通过螺旋线圈12,隔断螺旋天线20和棒状天线10之间的电耦合。
Patent CN-1318103-A (CN)
Title: 肺炎链球菌的核酸和蛋白质
Inventor: PAGE R W F LE
IPC: A61P31/04
Filed: 1999-07-27
Abstract: 本发明描述了新的肺炎链球菌蛋白质以及编码它们的核酸序列。还描述了它们在疫苗和筛选方法中的用途。
Patent CR-20140344-A (CR)
Title: Agonistas de mglu 2/3
Inventor: BAKER STEPHEN RICHARD
IPC: A61K31/16
Filed: 2014-07-17
Abstract: La presente invención se refiere a nuevos agonistas de mGlu2/3 útiles en el tratamiento de trastornos neurológicos o psiquiátricos.
Patent CR-20200494-A (CR)
Title: Novel peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers
Inventor: WEINSCHENK TONI
IPC: C07K14/47
Filed: 2016-08-26
Abstract: <p>The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.</p>
Patent CR-20200653-A (CR)
Title: Antibodies that target hiv gp120 and methods of use
Inventor: CARR BRIAN A
IPC: C07K16/10
Filed: 2019-07-02
Abstract: <p>Antibodies that bind to HIV gp120 and neutralize HIV are disclosed. Also disclosed are methods of using such antibodies alone or in combination with other therapeutic agents to treat or prevent HIV infection.</p>
Patent CR-20230244-A (CR)
Title: Anti-tspan8-anti-cd3 bispecific antibody and anti-tspan8 antibody
Inventor: YURI MASATOSHI
IPC: C12N15/63
Filed: 2021-11-15
Abstract: The present invention addresses the problem of providing an anti-TSPAN8-anti-CD3 bispecific antibody and an anti-TSPAN8 antibody each of which can be used for treatment or prevention in human bodies. A human-monoclonal-antibody-producing mouse is immunized with a cancer peritoneal dissemination cell isolated from a patient to produce a 16B11 antibody and a 16B12 antibody each of which has been bound selectively to the cancer peritoneal dissemination cell. These antibodies are anti-TSPAN8 antibodies capable of binding to a region lying between amino acid residue Nos. 126 to 155 in TSPAN8, and exhibit a potent binding activity to TSPAN8 expressed in a cancer peritoneal dissemination cell. Furthermore, an anti-TSPAN8(16B11)-anti-CD3 bispecific antibody which is produced on the basis of the sequence for 16B11 shows cytotoxicity to a TSPAN8-expressing cancer cell in vitro, and shows an anti-tumor activity to a cancer-affected mouse carrying a TSPAN8-expressing cancer cell and extends the survival period of a peritoneal dissemination model mouse in vivo.
Patent EC-SP024374-A (EC)
Title: Derivados del 4,5-dihidro-tiazol-2-ylamina y sus usos como inhibidores de no sintetasa
Inventor: DAMOUR DOMINIQUE
IPC: A61P9/10
Filed: 2002-12-09
Abstract: El presente invento concierne las composiciones farmacéuticas que contienen como principio activo un derivado del 4,5-dihidro- 1,3-tiazol-2-y lamina de fórmula (1), en donde R representa un radical -alq-S-alq-Ar, fenilo o fenil I sustituido por alcoxi o halógeno o una de sus sales farmacéuticamente aceptadas, los nuevos derivados de fórmula (1) y su preparación. Estos compuestos son útiles para prevenir y tratar enfermedades en las que una producción anormal de monóxido de nitrógeno (NO) por efecto de NO-sintetasa inducible (NOS-2) está implicada.
Patent EC-SP034500-A (EC)
Title: Guanidinobenzamidas novedosas
Inventor: BOYCE RUSTUM
IPC: C07D309/14
Filed: 2003-02-28
Abstract: Los compuestos de la fórmula (IA) y (IB) son nuevos donde las variables R1 a través de R10 tienen los valores establecidos en la presente. Tales compuestos tienen uso en tratar enfermedades tales como obesidad y diabetes del tipo II, y pueden proporcionarse como formulaciones farmacéuticas junto con un portador farmacéuticamente aceptable.
Patent EC-SP066343-A (EC)
Title: 6-(1,1-difluoroalquil)-4-aminopicolinatos y uso como herbicidas
Inventor: BALKO TERRY WILLIAM
IPC: A01N43/40
Filed: 2006-02-02
Abstract: Los ácidos 4-aminopicolínicos de la fórmula (I) en la cual Y representa -CF2(alquilo de C1-C3); y W representa -NO2, -N3, -NR1R2, -N=CR3R4 o -NHN=CR3R4 que tienen sustituyentes (1,1-di-fluofoalquilo) en la posición 6 y sus derivados de amina y ácido son herbicidas potentes que demuestran un amplio espectro de control de malas hierbas.
Patent EC-SP066460-A (EC)
Title: Formulación de aerosol destinada a la inhalación, que contiene un agente anticolinérgico
Inventor: SCHMIDT FRIEDRICH
IPC: A61K31/4745
Filed: 2006-03-27
Abstract: El presente invento se refiere a formulaciones de medicamentos para la inhalación, que como única sustancia activa contienen un compuesto de la Fórmula (I) (I)en el que X¯ significa un anión que está seleccionado de modo preferido entre el conjunto que consta de cloruro, bromuro, yoduro, sulfato, fosfato, metano-sulfonato, nitrato, maleato, acetato, citrato, fumarato, tartrato, oxalato, succinato, benzoato y p-tolueno-sulfonato, que como disolvente contienen etanol o mezclas de etanol y agua, por lo menos un ácido farmacológicamente compatible, así como eventualmente otras sustancias coadyuvantes y/o compuestos que forman complejos, farmacológicamente compatibles.
Patent EC-SP961668-A (EC)
Title: Variantes de dnasa i humana
Inventor: LAZARUS ROBERT A
IPC: C12N15/10
Filed: 1996-02-21
Abstract: Esta invención está relacionada a los resultados obtenidos en pesquisa deoxiribonucleasa humana I (IDNasa), un fosfodieserasa que es capaz de hidrolizar ácido polideoxiribonucleico. Se relaciona generalmente a formas modificadas (variantes) de la Dnasa I humana y su preparación por métodos de DNA recombinante, para composiciones farmacéuticas por las cuales su utilidad puede ser explotada clinicamente, y métodos de utilizar estas variantes DNasa I y composiciones de la misma, todo según consta en la memoria descrptiva reivindicaciones y dibujos.
Patent EC-SP982422-A (EC)
Title: Barreras a los liquidos en articulos absorbentes
Inventor: RONNBERG PETER
IPC: A61F13/15
Filed: 1998-02-19
Abstract: La invención se refiere a un artículo absorbente, tal como un pañal, una compresa sanitaria, un protector contra incontinencia o artículo análogo, que incluye bordes que se extienden longitudinal y transversalmente, una hoja inferior impermeable a los líquidos, una hoja absorbente, una hoja superior permeable a los líquidos que está destinada a estar junto al usuario durante el uso, y en cada lado de la linea central longitudinal de la hoja superior al menos una barrera longitudinal a los líquidos compuesta de un material alargado, esencialmente inelástico y esencialmente impermeable a los líquidos que tiene dos bordes longitudinales, de los que el primer borde está fijado a la hoja superior permeable a los líquidos o a su hoja inferior impermeable a los líquidos a lo largo o junto al borde longitudinal del artículo y cuyo segundo borde está fijado a un elemento elástico alargado, preestirado de tal manera que forme un borde de barrera fruncido, estirable que está destinado a estar contra el usuario cuando el artículo se lleve puesto. Un elemento en forma de lámina destinado a ser utilizado como barrera a los líquidos en un artículo absorbente, donde el elemento incluye un material alargado, esencialmente impermeable a los líquidos que tienen dos bordes que se extienden longitudinalmente, de los que el primer borde es libre y está destinado a fijarse al artículo absorbente y el segundo borde está fijado a un elemento elástico alargado preestirado de manera que forme un borde de barrera fruncido estirable, donde el elemento elástico se compone de un dispositivo elástico en forma de cinta que tiene un primer y segundo borde longitudinal de los que al menos el primer borde está fijado en estado preestirado al segundo borde del material esencialmente inelástico, de tal manera que los bordes unidos entre si formaran un primer borde de barrera fruncido estirable, e incluyendo una parte libre que se extiende longitudinalmente que forma un segundo borde de barreraestirable, esencialmente liso.