baber/WOPTO huggingface dataset:
Patent AU-2014224049-B2 (AU)
Title: HIV antigens and antibodies
Inventor: KILLIAN M SCOTT
IPC: A61K39/395
Filed: 2014-02-28
Granted: 2018-11-29
Abstract: The present invention relates to a method for reducing the occurance and/or severity of viral infections. The method embodies procedures for expanding HIV from the blood of HIV antibody negative donors and deriving a non-infectious virus particle product that is antigenic. The procedures for deriving the antigenic, non-infectious virus particle product are optimally designed to maintain the integrity of the envelope proteins while maximizing the depletion of capsid proteins and RNA. The resulting virus particle product, when introduced into humans or non-human animals, enables the production of antibodies that target the natural envelope macromolecular structure that is required for infectivity. The present invention can be applied to producing virus stocks from the blood of HIV-seronegative donors, for deriving non-infectious virus particles that retain intact envelope proteins, for producing anti-viral antibodies, and for administering anti-virus antibodies to patients.
Patent AU-2014233393-B2 (AU)
Title: Cell culture compositions with antioxidants and methods for polypeptide production
Inventor: VIJAYASANKARAN NATARAJAN
IPC: C12N5/00
Filed: 2014-03-14
Granted: 2020-05-28
Abstract: Cell culture media comprising antioxidants are provided herein as are methods of using the media for cell culturing and polypeptide production from cells. Compositions comprising polypeptides, such as therapeutic polypeptides, produced by the methods herein are also provided.
Patent AU-2014235734-B2 (AU)
Title: Container for surgical object and fluid monitoring system
Inventor: KASSAM MAHMOOD S
IPC: A61F13/84
Filed: 2014-03-12
Granted: 2016-09-22
Abstract: A container (101) for a system, method, and computer readable storage medium, for monitoring at least one of surgical object and fluid placed into the container are provided. The container includes a rigid top member (103) including at least one port opening (206) therein, having a recessed portion (902) of the underside of the rigid top member (103) along an outer perimeter, a rigid retaining ring (706) sized and shaped to match the size and shape of the recessed portion along the outer perimeter, and a flexible bag body (102) having an open top portion and a sealed bottom portion, an outer perimeter of the open top portion being folded over (704) the rigid retaining ring, the rigid retaining ring with the folded over perimeter of the open top portion of the flexible bag body being mated and locked in the recessed portion of the underside of the rigid top member along the outer perimeter in a fluid-tight seal arrangement.
Patent AU-2014246658-B2 (AU)
Title: Antibodies against human RYK and uses therefor
Inventor: MACHEDA MARIA LUISA
IPC: A61P25/28
Filed: 2014-04-02
Granted: 2018-10-04
Abstract: The present invention relates to antibodies and antigen-binding fragments thereof that bind RYK, in particular human RYK and their use in regulating RYK-associated activities. Specifically there is provided an isolated monoclonal antibody or antigen- binding fragment or derivative thereof that specifically binds to the extracellular domain of human RYK, in particular, the antibody or antigen-binding fragment thereof, binds specifically to the WIF domain of human RYK. Preferably, the antibodies of the present invention modulate RYK-associated activity, which includes RYK mediated signal transduction activity and modulation of the interaction of Wnts with RYK and, preferably, modulate Wnt induced signaling. In particular, the antibodies inhibit the binding of Wnt5a and inhibit Wnt induced phosphorylation of Dishevelled (Dvl) 2 and/or Dvl3 proteins.
Patent AU-2014326975-B2 (AU)
Title: Multiaptamer target detection
Inventor: OCHSNER URS A
IPC: C12N15/115
Filed: 2014-09-24
Granted: 2020-05-07
Abstract: Described herein are compositions comprising a first aptamer, second aptamer and a target that are capable of forming a ternary complex, and wherein the first aptamer and the second aptamer comprise C-5 pyrimidine modification schemes that are different, and methods of making and using such compositions.
Patent AU-2014334478-B2 (AU)
Title: Key and lock
Inventor: OJEDA GONZALEZ-POSADA ALEJANDRO
IPC: E05B19/00
Filed: 2014-10-08
Granted: 2018-04-05
Abstract: The key comprises at least one coding cavity (55) defining a hollow geometry for coding the key. The geometry includes at least one internal undercut (60a, 60b). The lock for validating a key comprises blocking means (21, 22) coupled to a driving part (14) and validating means (25, 26) which are coupled to the blocking means so as to change the state of the blocking means when the key used with the lock has a correct coding. The validating means (25, 26) protrude at least partially into the key cavity of the lock in order to introduce the validating means at least partially into the coding cavity (55) of the key and to sense the inner face of the coding cavity.
Patent AU-2015200559-B2 (AU)
Title: A belt fastener system including a buckle mechanism
Inventor: SKIPPER DEBRA RUTH
IPC: A44B11/28
Filed: 2015-02-05
Granted: 2020-02-27
Abstract: A BELT FASTENER SYSTEM INCLUDING A BUCKLE MECHANISM Abstract A waist belt fastener system includes a belt and a buckle mechanism attached to the belt. The buckle includes a rectangular frame having upper and lower sides that are curved outwardly, creating a convex shape that curves away from the belt wearer. At the rear side of the buckle frame where the buckle attaches to the belt, a fixed tongue member projects away from the buckle frame. This tongue member is fastened to the belt such as by a rivet, firmly anchoring and securing the buckle to the belt and inhibiting movement of the buckle relative to the belt. At the front side of the buckle frame, a fixed prong projects inwardly towards the buckle opening. The prong rests against the belt once it is threaded through the buckle opening. A hook and loop closure system is used to attach the ends of the belt together once the belt is inserted through the buckle opening.
Patent AU-2015201796-B2 (AU)
Title: Rationally designed, synthetic antibody libraries and uses therefor
Inventor: VASQUEZ MAXIMILIANO
IPC: C12N15/13
Filed: 2015-04-09
Granted: 2017-05-11
Abstract: Procedure to overcome the inadequacies inherent in the known methods for generating libraries of antibody-encoding polynucleotides by specifically designing the libraries with directed sequence and length diversity. The libraries are designed to reflect the preimmune repertoire naturally created by the human immune system and are based on rational design informed by examination of publicly available databases of human antibody sequences.
Patent AU-2015202661-B2 (AU)
Title: System and methods for online authentication
Inventor: RONDA TROY JACOB
IPC: H04L9/32
Filed: 2015-05-18
Granted: 2016-02-25
Abstract: A method of authenticating a network client to a relying party computer via a computer server, the network client being configured to communicate with the relying party computer and the computer server, the network client being further configured to communicate with a token manager, the token manager being configured to communicate with a hardware token interfaced with the token manager, the method comprising the computer server: receiving a transaction code from one of the token manager and the network client via a first communications channel; receiving a transaction request from the relying party computer via a second communications channel distinct from the first communications channel, wherein the transaction request comprises a transaction pointer that is associated with the hardware token; correlating the transaction pointer with the transaction code to identify the token manager; transmitting an authentication request message to one of the token manager and the network client via the first communications channel; polling for a response to the authentication request message from one of the token manager and the network client; receiving a credential from one of the token manager and the network client via the first communications channel; and transmitting an authorization signal to the relying party computer in response to the transaction request in accordance with a determination of validity of the credential and data originating from the hardware token, the authorization signal facilitating authentication of the network client to the relying party computer. WO 2010/094125 PCT/CA2010/000227 Z Co
Patent AU-2015222879-B2 (AU)
Title: Nitrobenzaldehyde proton release for manipulation of cellular acidosis
Inventor: GDOVIN MATTHEW
IPC: A61K41/00
Filed: 2015-02-26
Granted: 2019-12-05
Abstract: Certain embodiments are directed to photo-activated compounds for the manipulation of pH in a cell. In certain aspects the photo-activated compound is 2-nitrobenzaldehyde (NBA). Photo-activated compounds can be used as a targeted therapy for a variety of disease states and conditions, such as cancer.
Patent AU-2015238729-B2 (AU)
Title: Detaching an adhering charge from an inner wall of a grinding tube
Inventor: BOHNLEIN RUDOLF
IPC: B02C25/00
Filed: 2015-03-12
Granted: 2017-07-20
Abstract: The invention relates to a method for detaching an adhering charge (22) from an inner wall (20) of a grinding tube (6) and to an arrangement (8) for detaching an adhering charge (22) from an inner wall (20) of a grinding tube (6). According to the method, the grinding tube (6) is rotated back in a drive-free manner from a pre-determinable, assumed rotary position (28) by the weight force (30) of the adhering charge (22), wherein at least one movement state variable (40) of the grinding tube (6) is detected and the grinding tube (6) is braked while being rotated back in dependence on the at least one detected movement state variable (40) in order to detach the adhering charge (22) from the inner wall (20) of the grinding tube (6). The arrangement (8) comprises a detecting device (14), a drive unit (10), a braking device (12) and a control device (16) which are each provided to carry out the method according to the invention.
Patent AU-2015255010-B2 (AU)
Title: Material for use in lining pipes
Inventor: TOUGH DAVID PETER
IPC: D03D3/02
Filed: 2015-05-01
Granted: 2020-03-19
Abstract: A material for use in lining pipes is disclosed. Awarp-knitted tubular fabric (24, 64) in which the stitch used (for example a tricot stitch) is of a type that reconfigures as the tube is expanded radially to contract longitudinally is sufficiently flexible and compressible to enable it to conform to pipe structures. The fabric of this invention is infused with resin, which is cured once the liner is in place within the pipe. Potentially, this fabric may be thinner than known prior art materials, but exhibits comparable strength and conformability, which are necessary characteristics in the repair or rehabilitation of pipes. The use of a thinner fabric material reduces constriction of the pipe bore by repair and also offers the potential for cheaper lining material, as less resin is required. The fabric may be knitted from glass fibre yarn, which is non-toxic and a stronger material than generally used in the prior art.
Patent AU-2015296551-B2 (AU)
Title: Hybrid nanopore sensors
Inventor: BOYANOV BOYAN
IPC: G01N33/487
Filed: 2015-07-29
Granted: 2021-06-17
Abstract: In one aspect, a detection apparatus comprises a solid support with an array of solid-state nanopores and a plurality of lipid nanodiscs with protein nanopores, wherein the lipid nanodiscs are disposed on the solid support such that they form seals at the solid-state nanopores. In another aspect, a detection apparatus comprises one or more nanopores that are surrounded by a membrane, wherein each nanopore is tethered to an electrode.
Patent AU-2015301483-B2 (AU)
Title: System and computer method for visually guiding a user to a current interest
Inventor: EPSTEIN SYDNEY NICOLE
IPC: H04W4/021
Filed: 2015-08-14
Granted: 2020-12-10
Abstract: System and computer-implemented method of analyzing tags associated with a sequence of images presented to a user to present a current interest of the user is disclosed. An image from among a plurality of images is presented on an electronic display. The image is associated with a set of tags. An input is received indicating a user's preference for the image. A plurality of tags is processed based on the preference and the set of tags to determine a next set of tags from the plurality of tags. A next image is determined from the plurality of images based on the next set of tags. The next image represents a physical object, different from a physical object represented by the previous image. A sequence of images is generated by repeating the above process with the next image in place of the previous image for present a user's current interest.
Patent AU-2015304438-B2 (AU)
Title: Acid-addition salt of Trk-inhibiting compound
Inventor: TAKEUCHI JUN
IPC: A61P25/06
Filed: 2015-08-17
Granted: 2019-06-20
Abstract: In order to provide an agent for the prevention and/or treatment of Trk-related diseases, the present invention provides a compound that has selective inhibitory activity on Trk, persistently suppresses NGF vascular hyperpermeability, has no drug interactions, and also has exceptional absorbability and solubility in free bases. The compound of the present invention has selective inhibitory activity on Trk, persistently suppresses NGF vascular hyperpermeability, has no drug interactions, and has exceptional absorbability and solubility in free bases, and is therefore useful as a drug for the prevention and/or treatment of Trk-related diseases.
Patent AU-2015310976-B2 (AU)
Title: Microfluidic methods and cartridges for cell separation
Inventor: MERMOD NICOLAS
IPC: B01L3/00
Filed: 2015-09-01
Granted: 2020-09-24
Abstract: The invention discloses a method for selecting cells depending on their level of displaying and preferably secreting a protein of interest from a population of heterogeneously expressing cells, comprising: (a) contacting said cells with magnetic beads coated with an affinity group to the said cells, (b) mixing the said magnetic beads with the cells to capture the cells displaying/secreting the protein of interest, (c) performing at least one washing step to remove the non-captured cells, and (d) recovering the cells to which that magnetic beads have bound.
Patent AU-2015343083-B2 (AU)
Title: Neuro-attenuating ketamine and norketamine compounds, derivatives thereof, and methods
Inventor: NIVOROZHKIN ALEX
IPC: C07C225/20
Filed: 2015-11-04
Granted: 2020-07-23
Abstract: The present invention is directed to novel neuro-attentuating norketamine (NANKET) compounds according to any one of formulas (I - shown below), (I-A) and (I-B), or any of the compounds described in Tables A-D, or in any of the Examples provided herein, and pharmaceutically acceptable salts thereof, novel pharmaceutical formulations and novel methods of uses thereof. The present invention also features novel oral neuro-attenuating ketamine (NAKET) and neuro-attenuating norketamine (NANKET) modified-release pharmaceutical formulations, and novel methods of administration thereof, which ensure the steady release of a therapeutically effective amount of ketamine, norketamine, or derivatives thereof from the oral modified-release pharmaceutical formulations without neurologically toxic spikes in plasma concentration of the ketamine, norketamine, or derivatives during the release periods.
Patent AU-2015363779-B2 (AU)
Title: Dosing pump device for dosing metered amounts of a liquid product
Inventor: BALDEE JAAP WILLEM
IPC: A47J31/40
Filed: 2015-12-14
Granted: 2019-12-12
Abstract: A dosing pump for dosing metered amounts of liquid product, includes an inlet adapted to be fluidly connected to a storage container, an output adapted to be connected to a beverage dispensing machine for receiving metered amounts of liquid product, and a dosing chamber arranged for transferring a liquid from the inlet to the output. The dosing chamber is at least partly filled with a liquid different from the liquid product. The different liquid can be a cleaning fluid, or be food compliant. The dosing pump can be included in an exchangeable supply pack filled with the liquid product for connecting to a beverage dispensing machine, and the output can be adapted to be brought into fluid connection with a beverage dispensing machine. When associated with a beverage dispensing machine, the dosing pump can be operated to allow the different fluid to be pumped through the beverage dispensing machine prior to a first dosing cycle of liquid product.
Patent AU-2015364559-B2 (AU)
Title: Immunotherapy treatments and compositions
Inventor: EGGINK LAURA L
IPC: A61K38/00
Filed: 2015-12-17
Granted: 2020-03-26
Abstract: The present invention relates to compositions and kits comprising a peptide that activate the immune response and methods of using the composition for immunotherapy and cancer treatments. The peptide comprises an active peptide sequence of VQATQSNQHTPR. In some embodiments, the peptide may be tetravalent. For example, the peptide has the structure [(VQATQSNQHTPRGGGS)
Patent AU-2015394219-B2 (AU)
Title: Modular animal accommodation
Inventor: LOMIS DIMITRA
IPC: A01K1/03
Filed: 2015-05-11
Granted: 2017-12-07
Abstract: An animal accommodation facility is described including: a number of substantially airtight enclosures; each enclosure having at least one air inlet and at least one air outlet; an air delivery system which draws air from the atmosphere; an air exhaust system which exhausts air to the atmosphere; wherein the air delivery system delivers air to the at least one air inlet of each enclosure; and the air exhaust system receives air from the at least one air outlet of each enclosure; wherein the air delivery system includes a number of air delivery conduits and at least one air delivery conduit is dedicated to each enclosure; and wherein the air exhaust system includes a number of air exhaust conduits and at least one air exhaust conduit is dedicated to each enclosure.
Patent AU-2016207841-B2 (AU)
Title: Downhole actuator device, apparatus, setting tool and methods of use
Inventor: MOYES PETER
IPC: E21B34/14
Filed: 2016-01-18
Granted: 2021-03-25
Abstract: The invention provides an actuator assembly for a downhole tool and a method of use. The actuator assembly comprises an actuator device, which includes a housing and a piston element movable with respect to the housing. First and second fluid paths are configured to couple first and second sides of the piston element to at least one source of fluid pressure in a drive module, and an actuator member is configured to be coupled to a downhole device. The actuator member is movable between a first position and a second position to operate the downhole device in response to a force acting on the piston element. The actuator assembly comprises a pressure release mechanism which is operable to equalise pressure between the first and second fluid paths of the actuator device. The invention may be used in conjunction with a valve module which includes the pressure release mechanism, and the valve member preferably comprises a forward flow position, in which a first side of the piston element is pressurised to urge the piston element in a first direction, and a reverse flow position in which a second side of the piston element is pressurised to urge the piston element in a second direction, opposite the first direction. A preferred embodiment of the invention is setting tool incorporating the actuator assembly.
Patent AU-2016219050-B2 (AU)
Title: Methods and compositions for identifying non-alcoholic fatty liver disease
Inventor: DENNIS EDWARD A
IPC: G01N33/49
Filed: 2016-02-12
Granted: 2022-05-19
Abstract: The disclosure provides methods for differentiating between non-alcoholic fatty liver disease and non-alcoholic steatohepatitis. The method includes measuring eicosanoids and fatty acid levels in a biological sample. The disclosure provides a method of differentiating nonalcoholic steatohepatitis (NASH) from nonalcoholic fatty liver (NAFL) in a subject. The method includes obtaining a biological sample from the subject; treating the sample with an alkaline solution to release esterified eicosanoids and recovering the eicosanoids; and comparing the levels of at least one esterified eicosanoid in the biological sample obtained from the subject to a control sample obtained from a NAFL subject, wherein a difference in the levels of the at least one eicosanoid in the sample obtained from the subject compared to the control is indicative of NASH.
Patent AU-2016219536-B2 (AU)
Title: Optimal phase relationship
Inventor: EICK PETER M
IPC: G01V1/047
Filed: 2016-02-09
Granted: 2021-05-06
Abstract: Improved methods of gather high fidelity vibratory seismic surveys for ZenSeis® systems wherein at least one optimal phase encoding schemes for surveys having 2-8 vibratory sources are disclosed. These encoding schemes can be hard coded into the source controller and will allow for quality data to be obtained on each survey. Further, the data will also have the best separation during inversion processing steps, leading to an optimal seismic survey.
Patent AU-2016225845-B2 (AU)
Title: Elevator tension member
Inventor: GURVICH MARK R
IPC: B29C48/34
Filed: 2016-09-07
Granted: 2018-02-01
Abstract: A belt for suspending and/or driving an elevator car includes a tension member extending along a length of the belt, the tension member including a plurality of fibers bonded in a first polymer matrix, the plurality of fibers extending parallel to and discontinuous along a length of the belt and arranged with one or more lengthwise extending gaps between lengthwise adjacent fibers. A jacket substantially retains the tension member. A method of forming a tension member for an elevator system belt includes arranging a plurality of fibers into a fiber bundle. The plurality of fibers extend parallel to a length of the belt and have one or more lengthwise extending gaps between lengthwise extending fibers. The plurality of fibers is bonded to a first polymer matrix. Va ~ ~ 30 p - A 'I % '. 1~ / *1* I ~f II~s Wt# I - I I - - .. - 'to
Patent AU-2016259298-B2 (AU)
Title: Machine for development and deployment of analytical models
Inventor: DUGGAN DESMOND
IPC: G06F17/00
Filed: 2016-11-14
Granted: 2017-08-24
Abstract: A machine provides a system and interface to allow domain experts and other users to develop, deploy, and iterate on analytical models. The system facilitates building, deploying, and/or training analytical models, by, e.g., exposing analytical model configuration parameters to a user while abstracting model building and model deployment activities. The system can also determine resource loads or execution times for various analytical models and can schedule model execution accordingly. The system also provides a dynamically reconfigurable user interface for controlling the system. col 9 Co * 0) a) co a LU 0) (--C 1 c0011 y CD'~ 0 5O a . Q) 00I o 0 oCD CD-
Patent AU-2016263510-B2 (AU)
Title: Novel azetidine derivatives useful as modulators of cortical catecholaminergic neurotransmission
Inventor: PETTERSSON FREDRIK
IPC: C07D205/04
Filed: 2016-05-20
Granted: 2020-03-12
Abstract: The present disclosure relates to certain novel compounds of Formula (I) and to their utility in modulation of levels of monoamines, dopamine, norepinephrine and serotonin, in cerebral cortical areas of the mammalian brain, and more specifically for the treatment of central nervous system disorders.