baber/WOPTO huggingface dataset:
Patent NZ-507792-A (NZ)
Title: Melanocortin 1 receptor selective compounds
Inventor: SZARDENINGS MICHAEL
IPC: C07K19/00
Filed: 1999-05-05
Abstract: The compound of formula (1) is described wherein: R1, R2, R2a, R3, R4, R5, R6, R7, R8, R9, R10, R11 and R12 are each selected from H and methyl; R13, R14, R15 and R16 are selected from H and an alkyl group selected from methyl, ethyl, propyl, isopropyl, or wherein optionally one hydrogen in R13 and one hydrogen in R14 is exchanged for a bond between R13 and R14, or wherein optionally one hydrogen in R15 and one hydrogen in R16 is exchanged for a bond between R15 and R16, and wherein L1 and L2 are linker groups which are independently selected from the group consisting of single bond, methyl, ethyl; R19, R20 and R21 are selected from H and -CH2X, where X is H, alkyl, substituted alkyl, heteroalkyl, substituted heteroalkyl, alkenyl, substituted alkenyl, heteroalkenyl, substituted heteroalkenyl, alkynyl, substituted alkynyl, heteroalkynyl, substituted heteroalkynyl, cycloalkyl, substituted cycloalkyl, cycloheteroalkyl, substituted cycloheteroalkyl, cycloalkenyl, substituted cycloalkenyl, cycloheteroalkenyl, substituted cycloheteroalkenyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, functional group; NT is selected from H, hydroxyl, alkyl, amino acid analogue, polypeptide and functional group, and CT is selected from hydrogen, hydroxyl, alkyl, amino acid, amino acid analogue, polypeptide and functional group, and wherein each asymmetric center (*) is in R or S configuration; moiety A and moiety B are optionally exchanged for H, Hydroxyl, alkyl, amino acid, amino acid analogue, polypeptide of functional group; and optionally moiety D and moiety E are exchanged for amino acid or amino acid analogue The compound is capable of inhibiting NO(nitric oxide) production or the formation of nitrite, and is capable of decreasing the formation of interleukin 1 (IL-1), interleukin 6 (IL-6), and/or tumour necrosis factor a (TNF- a), to decrease production of nitric oxide and/or to down- regulate the activity of nitric oxide synthase (NOS), and is capable of stimulating the production of interleukin 8 (IL-8) and/or interleukin 10(IL-10). The compound can be used in the manufacture of a medicament for immunomodulation, for contact hypersensitivity, sensitization by a hapten, for affecting the induction of hapten tolerance, oedema, inflammation of blood vessels or vasculitis, for normalization of white blood cell counts, for stimulation of cAMP, allergy, hypersensitivity, bacterial infection, viral infection, inflammation caused by toxic agent, fever, autoimmune disease, radiation damage by any source including UV-radiation, X-ray radiation, g- radiation, a- or b-particles, sun bums, elevated temperature, mechanical injury and hypoxia, for inflammatory diseases of the skin, in the abdomen, of the eye and tear glands, ear, nose , mouth, heart, liver, pancreas, kidney and joints, and for stimulating pigment formation in epidermal cells, such as skin tanning for cosmetic reasons, or any other condition where darkening of skin colour is desired.
Patent NZ-508015-A (NZ)
Title: Stabilized pharmaceutical preparations of gamma- aminobutyric acid derivatives and process for preparing the same
Inventor: AOMATSU AKIRA
IPC: A61K9/16
Filed: 1999-05-10
Abstract: A stabilized pharmaceutical preparation of a 4-amino-3- substituted-butanoic acid derivative that can be obtained by incorporating an amino acid as a stabilizer is disclosed.
Patent NZ-509979-A (NZ)
Title: Soil-applied granules with controlled release of active ingredient(s) (soil-applied CR granules)
Inventor: STADLER REINHOLD
IPC: A01N25/26
Filed: 1999-07-28
Abstract: Soil-applied controlled-release (CR) granules which can be obtained by depositing (i) a coating containing active ingredients and a coating polymer onto a solid carrier or (ii) an active ingredient to a carrier and then a coating polymer is applied, in a fluidized bed with a defined heat input adjusted to from 6000 to 25000 KJ/kg of coating polymer is disclosed. A method for producing the soil- applied controlled-release (CR) granules and a method for combating phytopathogenic fungi, undesirable vegetation growth or undesirable insect infestation and/or for regulating vegetation growth by means of the controlled- release soil-applies granules is also disclosed.
Patent NZ-513575-A (NZ)
Title: Heteroaryl diazabicycloalkanes useful for treating or preventing a disease or a disorder responsive to the activity of nAChR modulators
Inventor: PETERS DAN
IPC: A61P29/00
Filed: 2000-04-27
Abstract: A diazabicycloalkane derivative or any of its enantiomers or any mixture thereof, an N oxide thereof, a pharmaceutically acceptable salt thereof, in a labeled or un-labeled form has the formula (I) wherein: n is 2 or 3; and m is 1, 2 or 3; one of R and R1 is hydrogen, alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, aryl, or aralkyl; and the other of R and R1 is an optionally substituted monocyclic 5 to 6 membered heterocyclic group or bicyclic heterocyclic group, composed of a 5 to 6 membered monocyclic heterocyclic group fused to a benzene ring or R and/or R1, together with the nitrogen atom to which they are attached, form an alkyl-onium salt, a dialkyl-onium salt, a cycloalkyl-onium salt, an alkyl-cycloalkyl-onium salt, a dicycloalkyl-onium salt, an alkyl-cycloalkylalkyl-onium salt, a cycloalkyl-cycloalkylalkyl-onium salt, or a dicycloalkylalkyl-onium salt. The diazabicycloalkane derivative is useful for treating or preventing a disease or a disorder responsive to the activity of nAChR modulators such as Alzheimer's disease, Parkinson's disease, memory dysfunction or attention deficit hyperactivity disorder or a disease caused by smooth muscle contraction, neurodegeneration, inflammation, chemical substance abuse or withdrawal symptoms caused by the cessation of intake of the chemical substance.
Patent NZ-517189-A (NZ)
Title: Device for applying labels
Inventor: GRANERO TORMO RICARDO
IPC: B65C9/28
Filed: 2000-07-27
Abstract: The device comprises a roller (2) carrying a tape (3) to which a plurality of labels (4) is adhered.  The tape runs along a guide-wedge (5) which produces an abrupt change in direction to detach the label (4).  The device is characterised in that a head (10) is connected to a suction circuit (12) and a blower means (13, 15).  The operation of the suction circuit and the blower means is controlled by a pneumatic distributor (16).  When the label (4) has been detached, suction is produced, and it is retained at the head (10), after which the label is blown (4) to project it energetically over the surface of the product (18), the force causing the label to adhere to the product.  The head (10) has a homogeneously multiperforated surface (19) allowing passage of the suction-blowing air.
Patent NZ-519157-A (NZ)
Title: Clamps and hangers
Inventor: LINDSAY BRENDAN JON
IPC: A47G25/34
Filed: 2002-05-23
Abstract: A garment hanger which is an assembly of (i) a unitary moulded component that defines two spaced jaw pairs and (ii) two biasing components, one for each jaw pair, wherein, as assembled, each jaw pair can be opened at least substantially as if articulated from a clamping condition by a mutual squeezing of extensions thereof against the bias provided by its biasing component, yet can be allowed to release to a clamping condition under the effect of such bias, and wherein the moulded component is of a solid plastics material with a moulded flow through link between each jaw of a jaw pair which holds or has held the jaws indexed one to the other ex-mould, in each case, for association with the biasing component, and wherein each biasing component holds its jaws in proximity, one to the other, so as to provide for reproducibility of relative jaw movement, and wherein, when engaging a suitable type garment for the hanger, the jaws open to an extent such that abutment, jaw against jaw, of like garment engaging hangers in a wardrobe, or otherwise similarly supported, will not have the affect of opening the jaws to release the garment, i.e. there being a direct line of force for such contact through each jaw pair that does not have the effect of opening the jaws further than the condition they have assumed in their clamping condition.
Patent NZ-525293-A (NZ)
Title: Microblade array impact applicator
Inventor: TRAUTMAN JOSEPH C
IPC: A61B5/15
Filed: 2003-04-11
Abstract: A device for impacting a penetrating member against the stratum corneum that comprises:- (a) A body (12) having a first end and a second end, the first end being adapted to receive the penetrating member; (b) A piston (14) slidably disposed within the body (12) for impacting the penetrating member against the stratum corneum; (c) An impact spring (20) adapted to provide an impact force to the piston (14) and bias the piston out of the first end of the body, wherein the impact spring (20) is energized when the piston is further disposed within the body; (d) A latching mechanism (22, 28) adapted to releasably engage the piston (14) with the body (12) by the use of a single hand after the piston (14) has been sufficiently disposed within the body (12); and (e) A releasing mechanism (46) for disengaging the latching mechanism (22, 28) whereby the impact spring (20) impacts the piston (14) against the penetrating member forcing the penetrating member into the stratum corneum.
Patent NZ-525723-A (NZ)
Title: 1,4-di-substituted piperidine antagonists for melanin-concentrating hormone (MCH) and their use in the treatment of obesity or diabetes
Inventor: MCKITTRICK BRIAN A
IPC: C07D413/06
Filed: 2001-12-17
Abstract: Disclosed herein are compounds represented by structural formula (I) or a pharmaceutically acceptable salt, ester or solvate thereof, wherein: W is R1-CR3R12NR4C(O)- or R11C(O)NR4-; the dotted line is an optional double bond; X is CHR8-, -C(O)-, or -C(=NOR9)-; Y is of formula (II); R1 is optionally substituted cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, heterocycloalkyl or heterocycloalkyl-alkyl; R2 is optionally substituted aryl or heteroaryl; R3 is alkyl, aryl or heteroaryl; R4 and R12 are H or alkyl; R8 is H, alkyl or alkoxyalkyl; R9 is H, alkyl or arylalkyl; R10 is H, alkyl or aryl; R11 is of formula (III), or, when R2 is R6-heteroaryl or R10 is not H, R11 can also be R5-phenyl(C0-C2alkyl; n is 1-3 and m is 1-5; R13 is 1 to 3 substituents independently selected from the group consisting of H, C1-C6 alkyl, halogen, -OH, C1-C6 alkoxy, -CF3, -OCF3, -NO2 and -C(O)CH3; and R14 is 1-3 substituents selected from H, alkyl, halogen, -OH, alkoxy and CF3; and pharmaceutical compositions containing the compounds and methods of using the compounds in the treatment of eating disorders, obesity and diabetes.
Patent NZ-525811-A (NZ)
Title: Resistant starch prepared by isoamylase debranching of low amylose starch
Inventor: SHI YONG-CHEN
IPC: A23L7/10
Filed: 2003-05-13
Abstract: Described is a resistant starch prepared by fully debranching a low amylose starch using isoamylase. Such resistant starch is useful in edible products, including nutritional supplements.
Patent NZ-532452-A (NZ)
Title: Method for producing rooted cuttings of arboreous plants
Inventor: MINATO AKIHISA
IPC: A01G1/00
Filed: 2002-10-01
Abstract: Disclosed herein is a method for producing rooted cuttings of arboreous plants that comprises inserting scions of arboreous plants in a medium and spraying the inserted scions with at least one member selected from the group consisting of carbon dioxide solution, oxygen solution, carbonate ion solution, and hydrogen carbonate ion solution, to accelerate their rooting abilities.
Patent NZ-537953-A (NZ)
Title: Injectable multimodal polymer depot compositions and uses thereof
Inventor: CHEN GUOHUA
IPC: A61K9/14
Filed: 2003-07-28
Abstract: An injectable depot composition is disclosed, which comprises: (a) a polymer matrix comprising a plurality of bioerodible, biocompatible polymers; wherein a first of the plurality of polymers is a low molecular weight (LMW) polymer; and a second of the plurality of polymers is a high molecular weight (HMW) polymer; the polymer matrix having a bi-modal molecular weight distribution of the plurality of polymers; (b) a solvent having a miscibility in water of less than or equal to 7% at 25 Deg C, in an amount effective to plasticize the polymer and form a gel therewith; and (c) a beneficial agent dissolved or dispersed in the gel.
Patent NZ-538172-A (NZ)
Title: Liquids packaging
Inventor: BLAKE GRAEME ASHLEY
Filed: 2005-02-10
Abstract: A drinking vessel for a liquids packaging product, the drinking vessel being adapted to engage with and seal the opening of a bottle. The drinking vessel incorporates a frangibly linked portion which is adapted to, (a) engage with the bottle when the drinking vessel is fitted to the bottle to seal the bottle, and to, (b) remain with the bottle when the drinking vessel is subsequently removed from the bottle. The drinking vessel is sized and shaped to allow the frangibly linked portion to expand slightly when engaging the frangibly linked portion with the bottle. Preferably the frangibly linked portion which is adapted to engage with the bottle is in the form of a ring. In a second aspect the invention comprises a liquids packaging product incorporating at least one drinking vessel and at least one bottle adapted to engage with the drinking vessel.
Patent NZ-539072-A (NZ)
Title: Fiber-reinforced decorative laminate
Inventor: KARAM FOUAD TORKUM
IPC: B32B29/02
Filed: 2005-03-29
Abstract: A method for the production of a fiber-reinforced decorative laminate 10 is disclosed. The method includes stacking, in a superimposed relationship, a decorative layer 20, and a fiber-reinforced core layer 30. The decorative layer 20, which includes one or more decorative sheets 22, is at least partially resin-impregnated, and at least partially cured. The fiber-reinforced core layer 30 includes at least one fiber-reinforced sheet that is substantially devoid of cellulose, at least partially resin-impregnated, and at least partially cured, and at least one cellulose sheet. The decorative and core layers 20, 30 are simultaneously cured under heat and pressure, and then cooled under pressure to create the fiber-reinforced decorative laminate 10.
Patent NZ-539145-A (NZ)
Title: Use of FAS gene to develop anthelmintic and/or insecticide
Inventor: GRANT WARWICK NORMAN
Filed: 2005-09-30
Abstract: The use of a nucleic acid molecule encoding fatty acid synthase (FAS) in a nematode or arthropod, to identify or produce FAS as a target for anthelmintic and/or insecticide development.
Patent NZ-542716-A (NZ)
Title: System and method for storing and accessing data in an interlocking trees datastore
Inventor: MAZZAGATTI JANE CAMPBELL
IPC: G06F17/00
Filed: 2004-02-27
Abstract: A system for generating a tree-based datastore comprises a processor; a memory coupled to the processor; and a tree-based datastore generator for creating at least one level of a tree-based datastore. The at least one level of the tree-based datastore comprises a first tree comprising a first root and at least one node of a plurality of nodes, a second tree comprising a second root and the at least one node of the first tree and at least a third tree comprising a third root and at least one of the plurality of nodes of the first tree.
Patent NZ-545337-A (NZ)
Title: Novel method for synthesizing esters of N-[(S)-1-carboxybutyl]-(S)-alanine and use thereof for synthesizing perindopril
Inventor: BREARD FABIENNE
IPC: C07K5/06
Filed: 2004-08-31
Abstract: Disclosed is a method for synthesizing derivatives of formula (I), in which R represents a linear or branched alkyl group (C1-C6), characterised in that a morpholinone is reacted either with allyl bromide or allyl triflate, in the presence of a base, to yield a compound which is hydrogenated in the presence of palladium-on-carbon or with iodopropane, which is subjected to the action of LiOH, then to the action of an esterification reagent, the product then being reacted with an oxidising agent to yield, after deprotection of the amino function, the compound of formula (I). The compounds of formula (I) are useful for synthesizing perindopril and pharmaceutically acceptable salts thereof.
Patent NZ-549414-A (NZ)
Title: Portable type fastener driving tool
Inventor: UEJIMA YASUTSUGU
IPC: B25C1/00
Filed: 2005-03-30
Abstract: A portable fastener driving tool comprises a main body 1 containing a fastener driving rod 17, a motor, which pushes the rod 17 forward in an axial direction, a head part 3 with a fastener guide 35 placed on the front of the main body 1, a fastener magazine which loads a fastener belt N made by connecting multiple fasteners n in a parallel fashion using a suitable material and a power operated fastener feed which feeds the fasteners n from the fastener belt N singly in front of the rod 17 in the direction in which they are arranged. The fastener feed is driven by an electric motor, which is different from the rod driving motor. The tool also includes a first sensor that detects the rod's movement, a second sensor that detects the fasteners n which are being fed and a brake which prevents the fastener feed motor from turning. When the first sensor detects that the rod has moved backwards, the brake will be released and the fastener feed motor will start feeding the fasteners. When the second sensor detects that the fastener feeding is complete it will stop the motor from rotating further by applying the brake.
Patent NZ-552137-A (NZ)
Title: New 4-benzylidene-piperidin derivatives
Inventor: BORZA ISTVAN
IPC: C07D413/12
Filed: 2005-07-21
Abstract: Disclosed are compound of formula (I), wherein the substituents are as defined in the specification, and processes for their preparation. The compounds are NR2B selective NMDA receptor antagonists.
Patent NZ-555529-A (NZ)
Title: A reflector assembly for energy concentrators with an annular array of concentric reflective elements
Inventor: DOL EDO
IPC: F24S23/70
Filed: 2005-12-02
Abstract: Disclosed is a reflector assembly (12) for an energy concentrator (10). The assembly comprises: a support structure (21) and a holding arrangement. The support structure has a plurality of support arms (22) with a reflective arrangement of an array of concentric annular reflective elements (28) spacedly arranged on the support arms, or on elongate mounting strips fixed to each or selected supported arms. Each reflective element has a reflective surface (30) shaped to reflect incident energy waves. The holding arrangement is arranged to hold the reflective elements in an orientation to direct the reflected energy waves thereof in a direction towards a focal zone (16) of the reflective arrangement. The holding arrangement has a set of holding devices for holding each reflective element on the support arms or mounting strips. Each holding device has a first holding member fixed to a support arm or mounting strip and adapted to engage with a part of an adjacent reflective element, and a second holding member having an engagement face adapted to engage with another part of the adjacent reflective element. The second holding member is adjustably positionable relative to the first holding member so that when secured to the first holding member the engagement face thereof causes the adjacent reflective element to be at the orientation.
Patent NZ-560958-A (NZ)
Title: 2-(4-oxo-4H-quinazolin-3-yl) Acetamides and their use as vasopressin V3 antagonists
Inventor: LETOURNEAU JEFFREY
IPC: C07D405/04
Filed: 2006-03-10
Abstract: Disclosed is a 2-(4-oxo-4H-quinazolin-3-yl)acetamide derivative of formula I, wherein the substituents are disclosed herein. Of particular importance are the 2-(4-oxo-4H-quinazolin-3-yl)acetamide derivatives selected from: 2-[2-(3-chloro-4-fluorophenyl)-4-oxo-6-(3-piperidin-1-ylpropoxy)-4H-quinazolin-3-yl]-N-isopropyl acetamide; N-isopropyl-2-[2-(3-methoxyphenyl)-4-oxo-6-(3-piperidin-1-ylpropoxy)-4H-quinazolin-3-yl] acetamide; 2-[2-(4-fluoro-3-methoxyphenyl)-4-oxo-6-(3-piperidin-1-ylpropoxy)-4H-quinazolin-3-yl]-N-isopropylacetamide; 2-{2-(3-chlorophenyl)-6-[3-(4-hydroxypiperidin-1-yl)propoxy]-4-oxo-4H-quinazolin-3-yl}-N-isopropylacetamide; 2-[2-(3-chlorophenyl)-4-oxo-6-(3-piperidin-1-ylpropoxy)-4H-quinazolin-3-yl]-N-isopropylacetamide; (S)-(+)-2-[2-(3-chlorophenyl)-6-(2-methyl-3-pyrrolidin-1-ylpropoxy)-4-oxo-4H-quinazolin-3-yl]-N-isopropylacetamide; 2-[6-(5-dimethylaminomethyl-2-fluorophenyl)-2-(3-methoxyphenyl)-4-oxo-4H-quinazolin-3yl]-N-isopropylacetamide; 2-[6-(3-dimethylaminomethylphenyl)-2-(3-methoxyphenyl)-4-oxo-4H-quinazolin-3-yl]-N-isopropylacetamide; N-tert-butyl-2-[2-(3-chlorophenyl)-4-oxo-6-(3-pyrrolidin-1-ylpropoxy)-4H-quinazolin-3-yl] acetamide and 2-[6-(3-dimethylaminomethylphenyl)-2-(3-methoxyphenyl)-4-oxo-4H-quinazolin-3-yl]-N-isopropylacetamide or a pharmaceutically acceptable salt or solvate thereof. Also disclosed is a pharmaceutical composition which comprises a 2-(4-oxo-4H-quinazolin-3-yl)acetamide derivative in admixture with one or more pharmaceutically acceptable auxiliaries. The use of the above derivatives in the manufacture of a medicament for the treatment or prevention of disorders or diseases influenced by modulation of the activity of the HPA axis is further disclosed, as is the use of the medicament for the treatment or prevention of depression.
Patent NZ-573155-A (NZ)
Title: Electric Socket
Inventor: HUANG FU-HSIANG
Filed: 2008-11-27
Abstract: An electric socket, comprises: a base (10) provided with a plurality of electrodes (11) and conduction 5 members (12) beside the electrodes (11); an upper casing (15) having a plurality of apertures (16) corresponding to the electrodes (11) respectively; a power control unit (20) including a control block (25) beside the conduction members (12) and a plurality of shutter members (26) pivoted on the base (10) and a spring (28). Each of the conduction members (12) is connected to a power source and keeps a predetermined distance away from the electrode (11) in a normal condition. The control block (25) is moved to bend the conduction members (12) toward the electrodes (11) and makes the conduction members (12) contacting the electrodes (11) respectively and each of the shutter members (26) is under the apertures (16) of the upper casing (15) to shut the apertures (16) and may be moved away from the apertures(16), and the spring (28) urges the shutter members (26) to positions of shutting the apertures (16).
Patent NZ-576166-A (NZ)
Title: Metal pipe with inner polyethylene lining and outer pvc film
Inventor: MO RUQUAN
IPC: F16L9/147
Filed: 2007-08-31
Abstract: A film face lining plastic metal pipe comprising a metal pipe body, characterized in that the inner surface of the metal pipe body is lined with innocuous food-level polyethylene or polypropylene layer, and that the outer surface of the metal pipe body is optionally covered with PVC film. An embodiment fully combines the advantages of metal and plastic. With the inner-layer plastic, the pipe is kept clean and sanitary without forming scale and rusting. Meanwhile, the metal pipe is separated from the fluid to prevent the transported fluid from being contaminated by the rust of the metal pipe. Furthermore, the metal pipe has strong mechanical strength, while the PVC film covering the outer surface of the pipe provides good protection to the pipe during use and construction.