baber/WOPTO huggingface dataset:
Patent IL-89222-A0 (IL)
Title: Preparation of metal-radionuclide-labelled proteins,certain novel compounds used therein and radiopharmaceutical compositions containing the labelled proteins
IPC: C07D333/36
Filed: 1989-02-08
Abstract: The invention relates to a method of preparing a protein or a proteinaceous material labelled with a metal-radionuclide and intended for diagnostic or therapeutic application, by reacting a protein or a proteinaceous material with an agent for coupling the radionuclide to the protein or the proteinaceous material, a protein conjugate being formed, and by then complexing the radionuclide with the conjugate thus formed to a radionuclide complex. A coupling agent is used which consists at least substantially of a thio compound of the general formula Y-R-S-X, wherein X is a hydrogen atom or a suitable protective group, R is a branched or non-branched, optionally substituted hydrocarbon radical having 1-10 carbon atoms, which may be interrupted by one or more hetero atoms, and Y is at least one terminal reactive group capable of reacting with a functional group from the protein or the proteinaceous material; or a cyclic condensation product of the thio compound of formula (I) having 5-7 ring atoms, wherein X and Y together constitute a reactive group capable of reacting with a functional group from the protein or the proteinaceous material; or a water-soluble salt of this condensation product. The invention also relates to novel compounds useful as coupling agents and protein conjugates made from them. The invention further relates to the labelled protein or proteinaceous material thus obtained and to a kit for the preparation of a radiopharmaceutical composition which comprises a protein conjuguate formed by reaction of a protern or a proteinaceous material with the coupling agent mentioned hereinbefore.
Patent IL-91721-A0 (IL)
Title: Method of providing a gating means and products produced thereby
IPC: B22D17/14
Filed: 1989-09-21
Abstract: The present invention relates to the use of a gating means in combination with a spontaneous infiltration process to produce a metal matrix composite body. Particularly, a permeable mass of filler material or a preform (2) is spontaneously infiltrated by molten matrix metal (5) to form a metal matrix composite body. A gating means (3) is provided which controls or limits the areal contact between molten matrix metal (5) and the filler material or preform (2). The use of a gating means (3) provides for control of the amount of matrix metal (5) which can contact the preform (2) or filler material which may result in less machining of a formed metal matrix composite body compared with a similar metal matrix composite body made without a gating means (3) and/or ameliorates the tendency of a formed metal matrix composite body to wrap due to the contact between the formed composite body and matrix metal carcass.
Patent IL-92046-A0 (IL)
Title: Determining seed viability
IPC: G01N33/48
Filed: 1989-10-18
Abstract: A method of determining the viability of crucifer seed, for example cabbage seed by detecting leakage of sinapine from non-viable seeds.
Patent IL-99244-A0 (IL)
Title: Penem compounds
IPC: C07D499/897
Filed: 1991-08-20
Abstract: PCT No. PCT/JP91/01100 Sec. 371 Date Feb. 19, 1993 Sec. 102(e) Date Feb. 19, 1993 PCT Filed Aug. 16, 1991 PCT Pub. No. WO92/03444 PCT Pub. Date Mar. 5, 1992Antibiotic penem compounds are represented by the following formula:    <IMAGE>  (I)  wherein R represents a group of the following formula:   <IMAGE>   in which R1 is a linear or branched, C1-C6 alkyl group, R2 is a particular substituted or unsubstituted alkyl, aryl or aralkyl group, n is an integer of 1 or 2, and R3 represents a specific substituted or unsubstituted alkyl, aryl or aralkyl group. Antibiotic compositions for oral administration are also described.
Patent FI-20010058-A0 (FI)
Inventor: JOHANSSON TOR
IPC: A22C13/00
Filed: 2001-01-11
Abstract: The invention relates to smokable sausage casings which are based on polyamide and polymers containing polyamide blocks and polyether blocks. The said smokable, heat-shrinkable tubular sausage casings are particularly suitable for the manufacture of cooked meat sausages, scalded-emulsion sausages, cooked or rapidly fermented sausages containing fat and smoked ham. The smokable sausage casing comprises 15-85 wt % of a polyamide (i) or a combination of polyamides (i) and 15-85 wt % of a polymer (ii) containing polyamide blocks and polyether blocks or a combination of polymers (ii).
Patent FI-20031886-A0 (FI)
Inventor: STAACK JENS
IPC: H04W4/10
Filed: 2003-12-22
Abstract: A mechanism and method for initiating a packet-based service session in a public mobile communication system, especially a service session for a group of users are disclosed. In order to accomplish a service initiation even if the terminals of the users are in a disconnected state with respect to the packet-switched domain of the mobile communication system, a triggering message is sent from one user terminal to the other terminals of the group. The triggering message includes information about a packet-based service session to be started, and it may be a message that can be sent via the mobile communication system to a mobile terminal that is in a disconnected state with respect to the packet-switched domain. In response to the reception of the triggering message, the other terminals are brought to a state allowing reception of packets belonging to the packet-based service session. When necessary, this feature involves establishing a connection from the other terminals to the packet-switched domain.
Patent FI-20115592-A0 (FI)
Inventor: PAULASAARI JYRI
IPC: C07D/
Filed: 2011-06-14
Abstract: Synthesis of thianthrene moiety containing silane and germane monomers and their polymerization is presented. The polymers show high refractive index, high transparency and excellent thermal stability. They are useful as dielectric films for semiconductor industry and for optical applications, including high-RI materials in CMOS image sensors. wherein Z is a metalloid, selected from silicon and germanium;
Patent IL-103057-A0 (IL)
Title: Dna sequences encoding gelonin polypeptide
IPC: A61K38/00
Filed: 1992-09-04
Abstract: The present invention provides the nucleotide sequence for a synthetic gene for the plant toxin gelonin and a process for producing, cloning and expressing this synthetic gene. The DNA sequence for a synthetic gene for gelonin as shown in sequence ID NO. 1. The present invention also provides expression vectors containing the DNA sequences for gelonin and cells transformed with these vectors. In addition, an immunotoxin comprising an antibody of conjugated to the protein gelonin.
Patent IL-103688-A0 (IL)
Title: Substituted biphenylpyridones,their preparation and pharmaceutical compositions containing them
IPC: A61K31/4418
Filed: 1992-11-09
Abstract: Substituted biphenylpyridones of the general formula <IMAGE> in which R<1>, R<2>, R<3>, R<4>, R<5> and A have the stated meanings, and D is a radical of the formula <IMAGE> in which R<13> and R<14> have the stated meanings, can be prepared by alkylation of pyridones on the nitrogen. The substituted biphenylpyridones are suitable as active ingredients in pharmaceutical compositions, especially in pharmaceutical compositions which lower blood pressure and have antiatherosclerotic effects.
Patent IL-110968-A0 (IL)
Title: Nucleosides, nucleotides and oligonucleotides comprising tris-4,4',4"-tert-butylphenylmethyl, as protected group and their preparation
IPC: C07H21/04
Filed: 1994-09-14
Abstract: The present invention relates to nucleosides, nucleotides and oligonucleotides whose basic structure contains a primary hydroxyl group protected by tris-4,4',4''-tert-butylphenylmethyl, to processes for the preparation of these nucleosides and nucleotides, to a process for preparing oligonucleotides, and to the use of such protected nucleosides, nucleotides and oligonucleotides.
Patent IL-115245-A0 (IL)
Title: Tumor necrosis factor inhibiting pharmaceuticals
IPC: A61K31/00
Filed: 1995-09-11
Abstract: Pharmaceutical compositions are described for preventing TNF toxicity, comprising as active ingredient the stereospecific (+) enantiomer having 3S, 4S configuration of delta 6 tetrahydrocannabinol type compounds. The compositions are particularly effective in alleviating and even preventing neurotoxicity due to elevated levels of TNF, including septic shock, cachexia and trauma. They are also effective in the treatment of certain chronic degenerative diseases characterized by TNF production, including autoimmune diseases.
Patent IL-124600-A0 (IL)
Title: Method for treating retinal ganglion cell injury using glial cell line-derived neurotrophic factor (gdnf) protein product
IPC: A61K38/18
Filed: 1996-11-22
Abstract: The present invention relates generally to methods for treating injury or degeneration of retinal ganglion cells by administering glial cell line-derived neurotrophic factor (GDNF). The invention relates specifically to methods for treating optic nerve injury or degeneration associated with glaucoma.
Patent IL-125895-A0 (IL)
Title: The use of an image enhancing moiety in the preparation of bioactivated nmr or optical imaging contrat agent from a prodrug
Inventor: LAUFFER RANDALL B
IPC: A61B5/055
Filed: 1997-03-25
Abstract: The present invention relates to improved diagnostic agents for Magnetic Resonance Imaging and optical imaging. In particular, this invention relates to MRI and optical imaging agents that allow for the sensitive detection of a specific bioactivity within a tissue. These agents are prodrug contrast agents which are bioactivated in vivo in the presence of the specific bioactivity. This invention also relates to pharmaceutical compositions comprising these agents and to methods of using the agents and compositions comprising the agents.
Patent IL-128337-A0 (IL)
Title: Cytostatic hydroxamic acid derivatives
IPC: A61K31/223
Filed: 1997-09-08
Abstract: Compounds of formula I are disclosedwherein R4 is an ester or thioester group, and R, R1, R2, and R3 are as defined in the specification are inhibitors of rapidly dividing tumor cells.
Patent IL-128564-A0 (IL)
Title: Lentiviral vectors
IPC: C12N15/00
Filed: 1997-10-17
Abstract: Retroviral vector particles capable of infecting and transducing non-dividing mammalian target cells, which vector particles may be based on letiviruses such as HIV and which have an RNA genome constructed so as to provide in the DNA provirus a non-lentiviral expression control element in the 5'LTR of the provirus.
Patent IL-138944-A0 (IL)
Title: Process for evaluating chemical and biological assays
IPC: C12Q1/68
Filed: 1999-04-22
Abstract: An analytical process is disclosed, for discriminating data acquired from samples with overlapping distributions, and for improving and assessing the statistical validity of hybridization signal in arrays of assays. The process includes method of convolving data into two or more discrete probability density functions representing signal and nonsignal, discrete fluors, or other convolved independent variables. The system uses the probability density functions to assign hybridization signals, objectively, to one of the modeled distributions. Subsequent processes assess variability inherent to the arrays, and use this assessed variation to establish reliability scores and confidence limits for complete hybridization arrays, and for discrete hybridization assays within arrays.
Patent IL-140944-A0 (IL)
Title: Use of aqueous protective coating compositions for industrial coatings and aqueous coating compositions
IPC: C09D5/02
Filed: 1999-08-11
Abstract: The invention is directed to the use of an aqueous protective coating composition containing a binder system and a combination of associative thickeners for industrial coatings. The combination of associative thickeners contains at least one associative thickener which is not a polyurethane thickener and is selected so that its concentration required by the specific application method is below the critical concentration C*, defined as the thickener concentration at which the coils of the thickener polymers start to overlap of entangle calculated according to the Mark Houwink equation.
Patent IL-143516-A0 (IL)
Title: COMPOUNDS AND METHODS FOR MODULATING ACTIVATION OF NF-k-B
IPC: C07K16/40
Filed: 1999-12-10
Abstract: Compositions and methods for modulating the activation of nuclear factor κB (NF-κB) are provided. The compositions comprise one or more agents that modulate ubiquitination of phosphorylated IκBα and/or IκBβ. Such compositions may be used for treating diseases associated with NF-κB activation. Modulating agents include human E3 ubiquitin ligases, antibodies thereto and variants thereof, as well as related proteins.
Patent IL-150554-A0 (IL)
Title: Obg3 globular head and uses therof for decreasing body mass
IPC: A61P3/10
Filed: 2001-01-10
Abstract: The present invention relates to the field of obesity research. Obesity is a public health problem that is serious and widespread. A compound, globular OBG3, has been identified that reduces weight gain in animals. This compound should be effective for reducing body mass and for treating obesity-related diseases and disorders. These obesity-related diseases and disorders include hyperlipidemias, atherosclerosis, diabetes, and hypertension.
Patent IL-151991-A0 (IL)
Title: Milk sampling apparatus and method
IPC: G01N1/18
Filed: 2001-03-28
Abstract: A milk sampling apparatus for use with an automated milking system. The apparatus may include a cassette wherein milk sample collecting elements may be placed, and at least one filling member capable of being placed above a selected one of the milk sample collecting elements by a positioning system, and capable of bringing a milk sample, representatively taken from milk yielded during the milking of an animal by the automated milking system, in the selected one of the milk sample collecting elements. Further, the milk sampling apparatus may include an agitating device, such as a shaking table, for agitating the milk sample.
Patent IL-152630-A0 (IL)
Title: Implantable device
IPC: A61B5/20
Filed: 2002-11-04
Abstract: An implantable medical device (10) for insertion into a body cavity. The device comprises an expandable balloon having a torroidal shape defining a hole (80), and an insert (82) configured to be received and secured in the hole. The device may be used in a method for treating urinary incompetence, a method for releasing a substance in the body, a method for monitoring a body cavity, or a method for imaging a body cavity.
Patent IL-152895-A0 (IL)
Title: Octave pulse data method and apparatus
IPC: H04L29/08
Filed: 2000-10-10
Abstract: Methods and apparatus are provided for sending data communications over wireless digital voice communications networks which transmit voice communications in voice frames, each of which contains a digitized segment of a voice communication in a voice frame format. The method including the steps of: encoding the data communication into a plurality of data frames, each of the data frames having the same format as the voice frame format; transmitting the data frames over the wireless digital voice communications network; and decoding the data frames to reconstruct the data communication. The apparatus includes: a processor for encoding the data communication into a plurality of data frames, each of the data frames having the same format as the voice frame format; and a transmitter for transmitting the data frames over the wireless digital voice communications network.
Patent IL-161349-A0 (IL)
Title: Record carrier and apparatus for scanning the record
IPC: G11B7/007
Filed: 2002-09-23
Abstract: A record carrier has a servo track ( 4 ) indicating an information track ( 9 ) intended for recording information blocks. The servo track ( 4 ) has a periodic variation of a physical parameter at a predetermined frequency and modulated parts for encoding position information at regular intervals. The modulated parts start with a bit sync element and are of a data type having a data bit element or of a word sync type having a word sync element. The bit sync element, word sync element and the data bit element being modulated according to a same predetermined type of modulation of the periodic variation. All distances between two adjacent of the elements constituting the modulated parts are unique.
Patent IL-173066-A0 (IL)
Title: Method for operating a laser
IPC: A61F9/008
Filed: 2006-01-10
Abstract: This invention relates to a method for operation of an irradiation laser whereby laser pulse sequences or pulses of varying length are modified during application such that the comparability of recorded transients is retained.
Patent IL-175596-A0 (IL)
Title: Low orbit missile-shaped satellite for electro-optical earth surveillance and other missions
Filed: 2006-05-11
Abstract: A low orbit optical imaging satellite has a long thin satellite body housing an optical telescope arrangement. A major part of the telescope arrangement has its optical axis roughly parallel to the direction of elongation and includes a mirror arrangement deployed to direct a line of sight of the optical telescope out sideways from the direction of elongation. The transverse dimensions of the satellite body are preferably minimized to be close to the optical aperture dimension of the optical telescope, thereby providing a high ballistic coefficient and high orbit lifetime for orbits in the low thermosphere.
Patent IL-191915-A0 (IL)
Title: High purity 17??-cyanomethyl-17??-hydroxy-estra-4,9-diene-3-one and process for the synthesis thereof
Filed: 2008-06-03
Abstract: The invention relates to a new process for the synthesis of high purity 17α-cyanomethyl-17β-hydroxy-estra-4,9-diene-3-one (further on dienogest) of formula (I) from 3-methoxy-17-hydroxy-estra-2,5(10)-diene of formula (V). The invention relates also to the high purity 17α-cyanomethyl-17β-hydroxy-estra-4,9-diene-3-one and pharmaceutical compositions containing that as active ingredient. The pharmaceutical compositions according to this invention contain high purity dienogest of formula (I) in which the total amount of impurities is less than 0.1%, while the amount of 4-bromo-dienogest is under the detection limit (0.02%) as active ingredient or at least one of the active ingredients and auxiliary materials, which are commonly used in practice, such as carriers, excipients or diluents. According to our invention the dienogest of formula (I) is synthesized the following way: i) 3-methoxy-17-hydroxy-estra-2,5(10)-diene of formula (V) is reacted with aluminum isopropylate in the presence of cyclohexanone in an inert organic solvent under heating; ii) the so obtained 3-methoxy-estra-2,5(10)-diene-17-one of formula (IV) is reacted with cyanomethyl lithium at a temperature between 0 and −30° C.; iii) the obtained 3-methoxy-17α-cyanomethyl-17β-hydroxy-estra-2,5(10)-diene of formula (III) is reacted with a strong organic acid in tetrahydrofuran solution; iv) the obtained 17α-cyanomethyl-17β-hydroxy-estr-5(10)-ene-3-one of formula (II) is reacted with 1-1.5 equivalent of pyridinium tribromide in pyridine solution at a temperature between 0 and 60° C., then the obtained crude dienogest of formula (I) is purified by recrystallization and preparative HPLC.
Patent RO-129827-A0 (RO)
Title: Low capacity water desalting plant
Inventor: MUSCALU VASILE
IPC: C02F1/04
Filed: 2014-04-30
Abstract: The invention relates to a sea water desalting plant needed for providing potable water to a dwelling house. According to the invention, the plant comprises some external water heating modules (A), a heat exchanger (B), some subassemblies (C) for the power supply and control of the modules (A), a general control panel (D) which also performs the control of the power supply and control subassemblies (C), where each module (A) comprises a preferably cylindrical metal tank (1), preferably having a capacity of 1...5 l, wherein there are two electrodes (2 and 3), namely an internal cylindrical electrode and an external helical electrode, respectively, which, by means of some metal upper and lower rods (4 and 5), respectively, with electrical conduction properties, are in contact with a transformer (6) belonging to the power supply and control subassembly (C), some pipes (11 and 12) for hot water delivery and cold water supply, respectively, being connected to an upper wall (b) and a lower wall (c) of the tank (1), respectively, the said electrodes (2 and 3) being preferably made of stainless steel, where the external electrode (3) represents a dipole of an antenna with a wavelength ( λ) of 2450 MHz which provides a vibration of the water molecule leading to the increase of the temperature in the total mass of the water volume, the discharge pipe (11) of the last external module (A) being connected to a heat exchanger (B).
Patent CU-22482-A1 (CU)
Title: Procedimiento para el secuestro de metales que formen sulfuros poco solubles en agua
Inventor: RIVAS HERNANDEZ DIANA FABIOLA
IPC: B01D15/00
Filed: 1995-02-07
Abstract: Relacionado con la Rama Química y otras especialmente interesadas en la eliminación de metales de disoluciones acuosas. Por medio d e este procedimiento es posible secuestrar de una forma efectiva iones de metales pesados mediante el empleo de sorbentes constituidos estructuralmente por un soporte (red polimérica de naturaleza diversa) y microcorpúsculos de un precipitante (sulfuro metálico poco soluble) ocluídos en sus poros o travéculas . La preparación de dichos sorbentes es sencilla desde el punto de vista tecnológico, utilizando materias primas relativamente económicas y accesibles. El proceso de basa en la reacción entre el precipitante y los iones metálicos que determina la formación de un producto aun menos soluble, que queda retenido en el soporte. Esta invención es aplicable en la descontaminación de masas de aguas conteniendo iones de metales pesados y en la recuperación de metales valiosos.
Patent IE-910352-A1 (IE)
Title: Preservatives
IPC: A01N59/00
Filed: 1991-02-01
Abstract: The invention relates to an aqueous preservative composition which comprises a biocidal cation (which may be free cation or may be present as part of a complex) and nitrite ion (which may be free anion or may be present as part of a complex), the composition having a pH of above 6.5 with the proviso that when the pH is above 9.25 and the composition contains ammonia or an amine, the composition may not contain a quaternary ammonium salt. Methods of treating wood with the compositions are also described.
Patent IE-910752-A1 (IE)
Title: A novel substituted-amine compound and a process for the¹preparation thereof
IPC: A61P25/00
Filed: 1991-03-06
Abstract: The invention relates to a substituted-amine compound of the following formula: <CHEM> pharmaceutical acceptable salts of it, processes for preparing it, pharmaceutical compositions comprising it and its use for the manufacture of medicaments.
Patent MA-21998-A1 (MA)
Inventor: BLIN PHILIPPE
IPC: B22D11/06
Filed: 1990-11-14
Abstract: This apparatus, intended for the casting of thin metal products, comprises one or two rolls (1), which are driven in rotation and whose walls are cooled, and lateral walls (3) defining a casting space (4). 
<??>The surface of each roll is divided into at least three circumferential zones, at least one (5) of the said zones having a roughness greater than that of the other zones (6). 
<??>This apparatus permits the implementation of the process according to the invention whereby certain longitudinal zones of the skins of the cast metal, which are solidified in contact with the cooled walls of the rolls, are preferentially driven on their own. 
<IMAGE>