baber/WOPTO huggingface dataset:
Patent NZ-522391-A (NZ)
Title: Use of fluoroalkoxybenzylamino derivatives of nitrogen containing heterocycles as substance P antagonists
Inventor: CHAPPELL PHILLIP BRANCH
IPC: A61P25/14
Filed: 2001-05-02
Abstract: Disclosed herein is a use of fluoroalkoxybenzylamino derivatives of nitrogen containing heterocyclic compounds, and specifically those compounds of the formula (I), (wherein X1 is H, alkoxy or alkyl; X2 and X3 are H, halo, alkyl or as defined in the specification; and Q is an N-containing saturated heterocyclic group as shown in the specification) or their pharmaceutically acceptable salts, for treating various CNS and other disorders.
Patent NZ-522591-A (NZ)
Title: Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1
Inventor: KURZ GUIDO
IPC: A61K31/4709
Filed: 2001-05-22
Abstract: Disclosed are compounds of formula (I), wherein: T is substituted thienyl or substituted phenyl, A is optionally substituted aryl or heteroaryl, and B is hydrogen or alkoxycarbonyl, or is linked to A to give a 6-membered aromatic or non-aromatic ring. The compounds are used for the manufacture of medicaments for the treatment of diseases mediated by 11-beta -hydroxysteroid dehydrogenase type I enzyme, such as diabetes and obesity.
Patent NZ-526175-A (NZ)
Title: Nucleic acid adjuvants
Inventor: HAYNES JOEL R
IPC: A61K39/39
Filed: 2001-11-26
Abstract: An adjuvant composition comprising first and second nucleic acid sequences is described to enhance an immune response against an antigen. The first nucleic acid sequence is a truncated A subunit coding region obtained or derived from a bacterial ADP-ribosylating exotoxin. The second nucleic acid sequence is a truncated B subunit coding region obtained or derived from a bacterial ADP-ribosylating exotoxin. The first and second nucleic acid sequences are operably linked to, or are each operably linked to, a promoter active in a mammalian cell. Use of the first and second nucleic acid is disclosed to be for the manufacture of a medicament for enhancing an immune response in a vertebrate subject against an antigen of interest. The antigen can be from a bacterial, viral or parasitic pathogen; and from the group consisting of an influenza virus, Herpes Simplex Virus (HSV) or a papilloma virus. A proviso explains that each of the truncated subunit coding regions has a 5' deletion and encodes a subunit peptide not having amino terminal bacterial signal peptide. A particle delivery device loaded with a particulate vaccine composition is also described.
Patent NZ-526695-A (NZ)
Title: Essential genes from c.albicans and a method for screening antimycotic substances using said genes
Inventor: LALANNE JEAN-LOUIS
IPC: C12Q1/68
Filed: 1999-09-13
Abstract: A polynucleotide having the sequence as shown in SEQ ID NO:4 and functionally equivalent fragments thereof, wherein the functional fragment has a sequence identity of at least 50% are described. The polynucleotide is used in methods for screening of antimycotic substances. Also described are diagnostic compositions for fungal infections comprising the polynucleotide, the protein or an antibody directed against the protein encoded by the polynucleotide. (62) Divided out of 510237
Patent NZ-527431-A (NZ)
Title: Inhibitor of monoamine uptake
Inventor: MATTIUZ EDWARD LOUIS
IPC: A61P17/02
Filed: 2002-02-20
Abstract: A compound of formula (I), namely, R-(-)-N-methyl 3-((2-methyl-4-hydroxyphenyl)oxy)-3-phenyl-1-aminopropane, useful in inhibiting the uptake of norepinephrine and serotonin in mammals.
Patent NZ-537144-A (NZ)
Title: Water repellent compositions for wood preservatives
Inventor: CUI FUTONG
IPC: C09K3/00
Filed: 2003-05-14
Abstract: Disclosed is a wax emulsion water repellent composition, comprising: a wax; a non-ionic surfactant having an HLB value greater than 11; an anionic surfactant comprising a monoethanolamine salt of a natural or synthetic carboxylic acid, present in an amount effective to stabilize said composition while it is used repetitively to pressure-treat wood; and water. Also disclosed are methods of treating wood using said composition and wood treated by the said composition.
Patent NZ-541551-A (NZ)
Title: Use of caspase enzymes for maturation of engineered recombinant polypeptide fusions
Inventor: KELLY ANDREW GRAHAM
IPC: C12P21/06
Filed: 2004-02-23
Abstract: A method for producing a polypeptide of interest in a biologically active form comprising: 1) producing, in a suitable non-human host, a fusion protein comprising an aminoterminal polypeptide, a linker sequence comprising a caspase group II recognition site and the polypeptide of interest, 2) cleaving said fusion protein by a caspase suitable for recognizing said caspase group II recognition site, which specifically cleaves the fusion protein at the junction of the linker sequence and the amino-terminal amino acid residue of the mature polypeptide of interest, and 3) isolating the biologically active polypeptide of interest.
Patent NZ-541852-A (NZ)
Title: Viral polymerase inhibitors
Inventor: BEAULIEU PIERRE L
IPC: C07D513/04
Filed: 2004-01-19
Abstract: Disclosed is an isomer, enantiomers, diastereoisomer or tautomer of a compound represented by formula I wherein A is N, B is C and the rest of the substituents are disclosed within the specification. Also disclosed is the above compound for use as a inhibitor of RNA dependent RNA polymerase, specifically as an inhibitor of HCV polymerase.
Patent NZ-542879-A (NZ)
Title: Real-time communications between telephone and internet users
Inventor: BOLE-FEYSOT YANN
IPC: H04L29/06
Filed: 2004-04-13
Abstract: A method of establishing a communications link between a first terminal having a dedicated routable address operating in a first network and a second terminal operating in a second network in which each terminal is identified by an alias address to which one of a number of routable addresses may be allocated is disclosed. The call set up request from the first terminal includes the address of an interworking function via which calls from the first network for the second network are routed. The call set up request is routed to the interworking function and the first terminal also signals to the interworking function the alias address for the terminal on the second network. The routable address allocated to the alias address is ascertained via the interworking function, and a link is established between the first and second terminals via the routable address. The first terminal can be a 3G mobile terminal operating in a 3G mobile network and the second terminal can be a PC operating on an IP network (H.323) and the second terminal alias address is an email address of the user of the PC. The 3G mobile terminal does not "dial" an email address and instead requests that a conventional telephone call (voice or video) be set up with the Inter-Working Function (IWF). The IWF function then sets-up the IP connection with the H.323 terminal on the basis of an email address sent to the IWF by the first terminal.
Patent NZ-545913-A (NZ)
Title: Quinazoline derivatives
Inventor: BRADBURY ROBERT HUGH
IPC: C07D401/12
Filed: 2004-09-15
Abstract: Disclosed is a quinazoline derivative of the Formula I wherein the substituents are disclosed within the specification. Also disclosed is the use of the above derivative or a pharmaceutically-acceptable salt thereof in the manufacture of a medicament for use in the treatment of cancer.
Patent NZ-550602-A (NZ)
Title: Plants comprising herbicide resistance gene encoding aryloxyalkanoate dioxygenase
Inventor: WRIGHT TERRY R
IPC: C12N15/82
Filed: 2005-05-02
Abstract: Disclosed are transgenic plants that are resistant to the herbicides 2,4-dichlorophenoxyacetic acid (2,4-D) and aryloxyphenoxypropionate (AOPP). The plants comprise a gene that encodes the enzyme aryloxyalkanoate dioxygenase (AAD) which is capable of degrading both 2,4-D and AOPP herbicides in an enantiospecific manner.
Patent NZ-553427-A (NZ)
Title: Hydrogen enriched hypochlorite free ionized water and method of producing same
Inventor: SATO KIMIHIRO
Filed: 2007-02-23
Abstract: A method of forming hydrogen-enriched hypochlorite free neutral ionized water comprising the steps of: dissolving a non-hypochlorite generating salt in water and subjecting the water containing the salt to a single electrolysis step only whilst continuously stirring the water during the electrolysis step at a temperature in the range from 4 to 9 degrees C.
Patent NZ-554494-A (NZ)
Title: RNAi modulation of RSV, PIV and other respiratory viruses and uses thereof
Inventor: BARIK SAILEN
IPC: A01N43/04
Filed: 2005-10-21
Abstract: Provided is the use a first and a second siRNA agent in the manufacture of a medicament for reducing levels of a viral titer from a Respiratory Syncytial Virus (RSV) and a Parainfluenza Virus (PIV), in a cell of the respiratory tract of a subject, wherein said first siRNA agent comprises a sense and antisense strand consisting of specified sequences; and wherein said second siRNA agent comprises a sense and antisense strand of specified sequences, and wherein the medicament co-administers intranasally the first and second siRNA agent.
Patent NZ-560914-A (NZ)
Title: Cellulose solutions in ionic liquids based upon imidazolium cations
Inventor: MAASE MATTHIAS
IPC: C07D233/58
Filed: 2006-04-07
Abstract: Disclosed is a solution comprising cellulose and an ionic liquid comprising anions and cations as solvent, wherein the cations comprise at least one atom selected from the group consisting of nitrogen, oxygen, sulfur and phosphorus which is present in protonated form, and wherein the ionic liquid comprises at least one imidazolium cation of formula (IVe) and oligomers comprising this structure, where the radical R is hydrogen; and the radicals R1 to R4 are each, independently of one another, hydrogen, or unbranched or branched C1-C18 alkyl which is unsubstituted.
Patent NZ-569438-A (NZ)
Title: Benzimidazole derivatives and their use for modulating the GABAA receptor complex
Inventor: LARSEN JANUS S
IPC: C07D235/06
Filed: 2007-03-22
Abstract: Disclosed herein are benzimidazole derivatives of formula (I), wherein substituents are as defined in the specification, pharmaceutical compositions containing these compounds, and methods of treatment therewith. Said compounds are useful in the treatment of central nervous system diseases and disorders which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases
Patent NZ-580968-A (NZ)
Title: Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
Inventor: SOLL MARK DAVID
IPC: C07C253/04
Filed: 2008-05-12
Abstract: Disclosed are aryloazol-2-yl-cyanoethylamine compounds represented by general formula (I) or salts thereof. An example of a compound of formula (I) is N-[2-(5-chloro-2H-benzotriazol-2-yl)-1-cyano-1-methylethyl]-4-trifluoromethoxybenzam ide. The compounds of formula (I) are used to treat an endoparasitic infection in a non-human mammal. Method for making the compounds of formula (I) are also disclosed.
Patent NZ-582443-A (NZ)
Title: Oral pharmaceutical solutions containing telbivudine
Inventor: SEKKAT NABILA
IPC: A61K9/08
Filed: 2008-07-10
Abstract: Disclosed is an oral solution comprising 20-50 mg/mL telbivudine or a pharmaceutically acceptable salt thereof, sodium saccharin, passion fruit flavor, benzoic acid, and citrate buffer, wherein said oral solution is buffered to a pH range of about 4 to about 5.
Patent NZ-587023-A (NZ)
Title: Composition comprising protein and disperse fat
Inventor: HANSEN KAAE OLE
IPC: A23L33/00
Filed: 2009-01-22
Abstract: Disclosed is a method for the manufacture of a composition comprising protein and fat in disperse form, the method comprising the following steps: (i) providing a suspension having a pH value higher than 7.0, said suspension comprising water, proteinaceous material, fat, and optionally alkali; (ii) incubating the suspension from (i) at a temperature in the interval 50 - 150 ºC; (iii) homogenizing the suspension from (ii) to form a dispersion; (iv) and, if desired, subjecting the dispersion from (iii) to a subsequent treatment; wherein the proteinaceous material in step (i) comprises fermented disintegrated vegetable-based proteinaceous material, and/or yeast-based proteinaceous material and wherein the suspension in step (i) comprises at least 5 % fat by weight of dry matter.
Patent NZ-587116-A (NZ)
Title: Compositions comprising phytoestrogens selective for estrogen beta receptor and dietary fibres
Inventor: DI LEO ALFREDO
IPC: A61P1/00
Filed: 2009-02-20
Abstract: Disclosed is the use of a composition comprising at least one phytoestrogen which is a selective agonist of the estrogen receptor-beta and at least one insoluble and indigestible fibre selected from the group consisting of non-starch polysaccharides for the manufacture of a medicament or a nutraceutical for the prophylactic or therapeutic local treatment of intestinal mucosa pathological conditions selected from the group consisting of adenopolyposis and its progression to advanced adenomas and adenocarcinoma, by oral administration.
Patent NZ-593231-A (NZ)
Title: Double paper layer sleeve, typically as cup, with binder between layers having thermally expandable micro-encapsulated particles
Inventor: FU THOMAS
IPC: B65D81/38
Filed: 2007-03-27
Abstract: A thermally expandable material 408 is applied as a binder between two layers of a cup 101 and typically contains expandable microspheres 502.
Patent NZ-597064-A (NZ)
Title: Papermaking and products made thereby with high solids glyoxalated-polyacrylamide and silicon-containing microparticle
Inventor: LU CHEN
IPC: D21H17/63
Filed: 2010-06-25
Abstract: Enhancement of papermaking drainage and retention properties of aqueous cellulosic suspensions used for production of paper or paper board with a retention/drainage additive system including high solids glyoxalated polyacrylamide polymers in combination with silicon-containing microparticles is described. The disclosure is also directed to the product of the described process.
Patent NZ-599045-A (NZ)
Title: New maytansinoids and the use of said maytansinoids to prepare conjugates with an antibody
Inventor: BOUCHARD HERVE
IPC: A61K31/537
Filed: 2010-09-30
Abstract: The disclosure relates to maytansinoid compounds of formula (I) which are cytotoxic agents, wherein the variables are as defined in the specification. The disclosure also relates to the use of said maytansinoids to prepare conjugates with an antibody having an affinity for tumor cells. The conjugate and also the compound of formula (I) can be used as anticancer agents, because the antibody makes it possible to have an agent that is selective towards the tumour cells, thus targeting the maytansinoid to a close vicinity of said cells or directly within them, which makes them suitable for treating solid and liquid tumours.
Patent NZ-602041-A (NZ)
Title: Heterocyclic inhibitors of histamine receptors for the treatment of disease
Inventor: NOBLE STEWART A
IPC: A61K31/495
Filed: 2011-03-10
Abstract: The present disclosure relates to compounds and methods which may be useful as inhibitors of H4R for the treatment or prevention of inflammatory, autoimmune, allergic, and ocular diseases. Compounds of the disclosure include: 5-(Piperazin-1-yl)-8-(thiophen-2-yl)tetrazolo[1,5-c]pyrimidine and 5-(Piperazin-1-yl)-8-(thiophen-3-yl)tetrazolo[1,5-c]pyrimidine
Patent NZ-609083-A (NZ)
Title: Methods for radiolabelling synthetic polymers
Inventor: SENDEN TIMOTHY JOHN
IPC: B82Y5/00
Filed: 2009-04-23
Abstract: Disclosed is a method for preparing a radiolabeled synthetic polymer, the method comprising contacting a synthetic polymer with a carbon encapsulated nanoparticle composite having a radioactive particulate core in an aqueous medium comprising an electrolyte concentration or pH selected to promote short-range attractive forces between the nanoparticles and the synthetic polymer by attenuating long- range electrostatic repulsive forces, wherein the synthetic polymer is selected from the group consisting of polystyrene, polypropylene, polyurethane, polyvinyl chloride, polyamides, polystyrene sulphonate, teflon, polyester, polyethylene terephthalate, poly(butylene terephthalate) (PBT), poly(ethylene oxide) (PEO), polylactide (PLA), polyglycolide (PGA), poly(lactide-co-glycolide) (PLGA), poly(e-caprolactone), polydioxanone, trimethylene carbonate, polyanhydride, poly[bis(p-carboxyphenoxyl) propane:sebacic acid; and wherein the carbon encapsulated nanoparticle composite is a carbon encapsulated 99mTc, 113mIn, 111In, 198Au, 64Cu, 213Bi, 57Co, 51Cr, 165Dy, 169Er, 59Fe, 153Gd, 166Ho, 177Lu, 103Pd, 81Rb, 82Rb, 186Re, 188Re, 75Se, 153Sm, 117mSn, 89Sr, 201Th, 90Y, or 169Y nanoparticle having a diameter of 10 to 500 nanometres.
Patent NZ-614776-A (NZ)
Title: Substituted diaminocarboxamide and diaminocarbonitrile pyrimidines, compositions thereof, and methods of treatment therewith
Inventor: BENNETT BRYDON L
IPC: C07D409/12
Filed: 2012-04-20
Abstract: Provided are substituted diaminocarboxamide pyrimidine compounds, of general formula (I), and substituted diaminocarbonitrile pyrimidine compounds, of general formula (IB), where the variables are as defined in the specification. Examples of the compounds include 4-(isopropylamino)-2-((1R,4R)-4-(2,2,2-trifluoroethoxycyclohexylamino)pyrimidine-5-carboxamide and 2-((1R,4S)-4-ethoxycyclohexylamino)-4-((1S,3R)-3-hydroxycyclohexyl-amino)pyrimidine-5-carbonitrile. The compounds are JNK1/JNK2 inhibitors. The compounds may be useful in the treatment of liver fibrotic disorders such as non-alcoholic steatohepatitis, steatosis, cirrhosis, primary sclerosing cholangitis, primary biliary cirrhosis, hepatitis, hepatocellular carcinoma, or liver fibrosis coincident with chronic or repeated alcohol ingestion, with infection, with liver transplant, or with drug induced liver injury.
Patent NZ-624110-A (NZ)
Title: An aerosol generating device with air flow nozzles
Inventor: DUBIEF FLAVIEN
IPC: A24F40/485
Filed: 2012-12-05
Abstract: An aerosol generating device 101 comprising a vaporizer for heating an aerosol-forming substrate 115, a plurality of air flow vents 121, and at least one air outlet 123. The air flow vents 121 and the air outlet 123 are arranged to define an air flow route between the air flow vents and the air outlet. In each of the plurality of air flow vents 121 is an air inlet vent arranged to direct air towards the vicinity of the vaporizer in a direction across the surface of the vaporizer so as to manage particle size in the aerosol.
Patent NZ-700749-A (NZ)
Title: Device for facilitating assembly of a product, such as furniture
Inventor: NILSSON PETER
IPC: F16B13/00
Filed: 2013-06-14
Abstract: The present disclosure relates to a device for facilitating assembling of a product involving attaching a first surface, of a first part, to a second surface, of a second part. The device comprises a first unit (9) intended to be embedded in the first surface and a second unit (11) unit intended to be embedded in the second surface, and having a cavity (35) that is open at the second surface. The first unit (9) comprises a piston (17), which is moveable between a retracted position and an extended position, where the piston (17) extends out of the first unit (9). The second unit (11) comprises an activator part (31) that interacts magnetically with the piston (17) such that the piston (17) moves to the extended position, extending into the cavity (35), when the first and second surfaces are in contact and the first and second openings are aligned. A spring (25) is arranged to urge the piston (17) towards the retracted position, the force applied on the piston (17) by the spring (25) being exceeded by the force applied by the activator part (31) when the first and second surfaces are in contact and the first and second units (9 and 11) are aligned.
Patent NZ-704147-A (NZ)
Title: Partially saturated nitrogen-containing heterocyclic compound
Inventor: SHIRASAKI YOSHIHISA
IPC: C07D513/04
Filed: 2013-07-29
Abstract: Provided is a compound which is represented by general formula (I’) and has an excellent PHD2-inhibiting activity or a pharmaceutically acceptable salt thereof. (In the general formula (I’), W, Y, R2, R3, R4 and Y4 are as defined in the description.)
Patent NZ-705596-A (NZ)
Title: Subsea processing
Inventor: HOLM HENNING
IPC: B01D19/00
Filed: 2013-08-06
Abstract: There is described subsea apparatus and a method for processing fluid from a well. In an embodiment, a pipeline may be arranged to carry the multiphase fluid containing liquid and gas from the well. An outlet extending through a wall of the pipeline may let gas out of the pipeline from said region and through the outlet to separate said gas and liquid. A compressor may be connected to the outlet to compress the separated gas. Separated liquid may be conveyed along a sloping portion of the pipe to a low point in the seabed terrain, and may be conveyed to a pump for boosting the flow of liquid. The pump may be located in an excavated hole or glory hole below the seabed. The pipeline extends a substantial distance away from the well, such that the pipeline portion upstream of the outlet acts to cool the fluid in the pipeline and to reduce liquid content in the gas. The use of the pipeline for cooling upstream, reduces or eliminates the need for further cooling equipment upstream of the compressor.
Patent NZ-708757-A (NZ)
Title: Air spring counterbalance
Inventor: BRIAN ROY SKOTTY
IPC: F16F9/04
Filed: 2013-09-24
Abstract: Disclosed is a system for moving a movable barrier, such as a garage door (see figure 11). The system comprises a fluid-based spring counterbalance mechanism (800) with a fluid based spring or rubberised bladder (510) that is located between two plates (520, 530) and is compressed or expanded by a translational cable (550) and pulley or caster (560) system when a garage door is opened or closed e.g. by a rotating shaft (580). The spring opposes the downward force of the garage door or wing.