baber/WOPTO huggingface dataset:
Patent DE-69524740-T2 (DE)
Inventor: LOEB A
IPC: C12N9/12
Filed: 1995-05-02
Granted: 2002-08-14
Abstract: The present invention provides isolated nucleic acid molecules encoding a Herpesviridae thymidine kinase enzyme comprising one or more mutations, at least one of the mutations encoding an amino acid substitution upstream from a DRH nucleoside binding site which increases a biological activity of the thymidine kinase, as compared to unmutated thymidine kinase. Within another aspect, one of the mutations is an amino acid substitution within a DRH nucleoside binding site which increases a biological activity of the thymidine kinase, as compared to unmutated thymidine kinase. Also provided are vectors suitable for expressing such DNA molecules, as well as methods for utilizing such vectors.
Patent DE-69531306-T2 (DE)
Inventor: AMICK DEAN
IPC: C22C33/02
Filed: 1995-10-18
Granted: 2004-02-12
Abstract: High specific gravity, lead free shotshell pellets are produced by preparing an iron-tungsten alloy having a specific gravity of at least 8 g/cc, melting the alloy at a temperature of about 1550 DEG -1760 DEG  C., pouring the melted alloy through at least one orifice of a sieve having a specific sized opening so as to produce a desired final product size, and allowing the melted alloy to fall by gravity through a gaseous medium to form drops of molten metal, and cooling the individual molten drops to form spherical metal pellets. A plurality of orifices of different sizes may be used in order to form a desired distribution of shot pellet sizes.
Patent DE-69535363-T2 (DE)
Inventor: SKOTNICKI JERAULD STANLEY
IPC: A61K31/00
Filed: 1995-04-14
Granted: 2007-04-19
Abstract: A compound of structure (I)   
wherein R 1  and R 2  are each, independently, hydrogen or - CO(CR 3 R 4 ) b (CR 5 R 6 ) d CR 7 R 8 R 9  ; 
R 3  and R 4  are each, independently, hydrogen, alkyl, alkenyl, alkynyl, trifluoromethyl, or -F; 
R 5  and R 6  are each, independently, hydrogen, alkyl, alkenyl, alkynyl, -(CR 3 R 4 ) f OR 10 , -CF 3 , -F, or -CO 2 R 11 , or R 5  and R 6  may be taken together to form X or a cycloalkyl ring that is optionally mono-, di-, or tri-substituted with - (CR 3 R 4 ) f OR 10 ; 
R 7  is hydrogen, alkyl, alkenyl, alkynyl, -(CR 3 R 4 ) f OR 10 , -CF 3 , -F, or -CO 2 R 11 ; 
R 8  and R 9  are each, independently, hydrogen, alkyl, alkenyl, alkynyl, -(CR 3 R 4 ) f OR 10 , -CF 3 , -F, or -CO 2 R 11 , or R 8  and R 9  may be taken together to form X or a cycloalkyl ring that is optionally mono-, di-, or tri-substituted with -(CR 3 R 4 ) f OR 10 ; 
R 10  is hydrogen, alkyl, alkenyl, alkynyl, tri-(alkyl)silyl, tri-(alkyl)silylethyl, triphenylmethyl, benzyl, alkoxymethyl, tri-(alkyl)silylethoxymethyl, chloroethyl, or tetrahydropyranyl; 
R 11  is hydrogen, alkyl, alkenyl, alkynyl, or phenylalkyl; 
X is 5-(2,2-dialkyl)[1,3]dioxanyl, 5-(2,2-dicycloalkyl)[1,3]dioxanyl, 4-(2,2-dialkyl)[1,3]-dioxanyl, 4-(2,2-dicycloalkyl)[1,3]dioxanyl, 4-(2,2-dialkyl)[1,3]dioxalanyl, or 4-(2,2-dicycloalkyl)[1,3]dioxalanyl; 
b = 0-6; 
d = 0-6; and 
f = 0-6 
with the proviso that R 1  and R 2  are both not hydrogen and further provided that either R 1  or R 2  contains at least one -(CR 3 R 4 ) f OR 10 , X, or -(CR 3 R 4 ) f OR 10  substituted cycloalkyl group, or a pharmaceutically acceptable salt thereof which is useful as an immunosuppressive, antiinflammatory, antifungal, antiproliferative, and antitumor agent.
Patent DE-69602515-T2 (DE)
Inventor: ASTLE BRIAN
IPC: H04N5/14
Filed: 1996-06-12
Granted: 2000-03-02
Abstract: A system and method for realtime occlusion processing for seamlessly and realistically blending an inserted image such as an advertisement into a region of a live broadcast image without obscuring the action of the live image. The average color and intensity of a synthetic reference image containing at least some of the region to be replaced is compared to the average color and intensity of the current live broadcast image to determine the difference between the two images. The resulting difference image obtained from processing the current image and synthetic, reference image determines areas of the intended insertion region within the current image which are obscured by live action. The processor then generates an occlusion mask based on the difference image and only those pixels that are unoccluded within the intended insertion region are allowed to be inserted into the live broadcast.
Patent DE-69611556-T2 (DE)
Inventor: OETIKER HANS
IPC: F16L33/02
Filed: 1996-02-13
Granted: 2001-08-23
Abstract: An open clamp structure in which overlapping band portions (11a, 11b) are mechanically connected by a spring (25) separate from the clamping band (11); the spring (25) is of low profile having a top portion (26) and lateral portions (27a, 27b) passing over into mutually facing end portions (28a, 28b) which are provided with tongue-like extensions (29a, 29b) adapted to engage in tunnel-shaped embossments (17, 18) in corresponding parts of the clamping band. Means (40, 140) for limiting the extent of stretching to which the spring can be subjected and also providing at the same time a guide function to keep overlapping band portions mutually aligned includes either two tab-like members (41a, 41b) extending in the longitudinal direction within two narrow slot-like openings (42a, 42b) only slightly wider than the thickness of the clamping band and of predetermined length or a tunnel-shaped embossment (141) in the inner band portion extending in an elongated opening (142) of only slightly larger width than the embossment to provide the guide function. <IMAGE>
Patent DE-69614867-T2 (DE)
Inventor: COURTNEY STEPHEN MARTIN
IPC: A61P35/00
Filed: 1996-06-24
Granted: 2002-04-11
Abstract: Compounds of formula (I): wherein: R is halogen; Y is hydrogen, NH2, SH or OH; X is: wherein: either R1 or R2 is a bond, with the other being hydrogen; either R3 or R4 is hydrogen, with the other being hydrogen, OH, OAc or NHAc; R5 is OH or OAc; either R7 or R8 is hydrogen, with the other being OH or OAc; R9 is hydrogen, CH2OH or CH2OAc; with the proviso that when R4 is OH, OAc or NHAc then R8 is hydrogen; and enantiomers of such compounds, are disclosed. Pharmaceutical formulations comprising such compounds, their use in the treatment of various disease states, and methods of treatment employing the compounds are also provided.
Patent DE-69616741-T2 (DE)
Inventor: KANEKO AKIHITO
IPC: H01M4/24
Filed: 1996-08-28
Granted: 2002-05-08
Abstract: A rare earth metal/nickel-base hydrogen absorbing alloy having a composition represented by formula (1): (R1-x Lx )(Ni1-y My )z , (wherein R represents La, Ce, Pr, or Nd; L represents Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu, Y, Sc, Mg, or Ca; and M represents Co, Al, Mn, Fe, Cu, Zr, Ti, Mo, Si, V, Cr, Nb, Hf, Ta, W, B, or C; 0,01 ≤ x ≤ 0.1; 0 ≤ y ≤ 0.5; and 4.5 ≤ z ≤ 5.0), wherein the content of crystals with the number of reversed-phase boundaries present perpendicularly to the C axis of crystal grains in the alloy being 2 to less than 20 per 20 nm in the direction of the C axis is 10 to less than 95 vol.% and the amount of L in the formula (I) present in the reversed-phase region is 60 to less than 95 % of the amount of L added. The negative electrode for the nickel-hydrogen secondary battery can simultnaneously improve all of the initial activity, battery capacity, and battery life.
Patent DE-69617441-T2 (DE)
Inventor: ASKEA W
IPC: G01N33/44
Filed: 1996-08-21
Granted: 2002-07-25
Abstract: A system for performing a flexometer test includes a balanced beam supporting an anvil upon which a viscoelastic material is placed, the balanced beam being balanced upon a rotatable shaft and pivotable about the axis of the rotatable shaft, an assembly for applying a static load to the material, a hammer opposite the anvil for applying a dynamic strain to the material, and a sensor which senses permanent dimensional changes in the material.
Patent DE-69701540-T2 (DE)
Inventor: DRATNER JOHANNES
IPC: H05B7/12
Filed: 1997-02-19
Granted: 2000-07-27
Abstract: System for connection of pneumatic and/or hydraulic hoses (11) on composite electrodes (12) for arc furnaces, the electrodes (12) comprising at least one hollow adapter (13) associated at the lower part with a replaceable graphite element (14), the electrode (12) cooperating with an electrode-holder arm (15) and being displaceable axially in relation to that electrode-holder arm (15), the hoses (11) being associated at one end with a first connection assembly (18a) associated with supporting means (17), the adapter (13) including a solidly attached second connection assembly (18b) mating functionally with the first connection assembly (18a), the first (18a) and second (18b) connection assemblies comprising mating connecting elements (19a, 19b) equipped with elements to interrupt the flow of the fluid which can be temporally actuated, the supporting means (17) associated with the first connection assembly (18a) having a first inactive position temporally solid with the electrode-holder arm (15) and a second working position released from the electrode-holder arm (15) and temporally solid with the second connection assembly (18b) associated with the adapter (13), the transition from the first inactive position to the second working position of the supporting means (17) taking place according to the position of the electrode (12) in a defined position of engagement/disengagement. <IMAGE>
Patent DE-69707110-T2 (DE)
Inventor: SKOGLUND B ULF
IPC: G06T11/00
Filed: 1997-03-07
Granted: 2002-06-20
Abstract: The invention relates to a method and an apparatus for providing high fidelity reconstruction built on a grid of an observed sample. An input means (10, 11, 13, 14; 40, 43, 14; 52, 13, 14) provides observed data of the sample. An estimated distribution means (19; 44; 54) provides an initial estimated distribution of the sample. A prejudice distribution means (21, 25, 15; 45, 15; 54, 15) provides a blurred prior prejudice distribution using estimated data. A calculating means (12) calculates in an iterative process for each iteration: a new estimated distribution of the sample using comparison between the estimated distribution in the next preceding iteration and said observed data of the sample from said in-put means; a new prior prejudice distribution on the new estimate less blurred than the prior prejudice distribution in the next preceding iteration. The calculation means (12) continues the iterations until the difference between the new estimated distribution and the next preceding estimated distribution is less than a predetermined condition. The calculated result is presented.
Patent DE-69724775-T2 (DE)
Inventor: TEVLIN JOHN
IPC: B65D79/00
Filed: 1997-08-13
Granted: 2004-03-18
Abstract: The receptacle (1) is in the form of a closed hollow body (2) including a side wall (2a) and two end walls, one of which (2b) called the "emptying" wall, is designed to be manually ruptured in order subsequently to empty the receptacle. The hollow body (2) is made in a single piece, in particular by molding and includes, in its other end wall (2c), called the "filling" wall, an orifice (3) for filling the hollow body; the receptacle also includes means for closing said orifice (3), e.g. in the form of a removable cap (7). Preferably, the receptacle includes an add-on hollow part (8) for containing a gas under pressure and designed to be fixed through the filling wall (2c) of the hollow body (2), being inserted into the hollow body via the filling orifice (3) in said wall, and including one or more escape openings (8b) making it possible, once the hollow part has been fixed through the filling wall (2c) to put the inside of the hollow part (8) into communication with the inside of the hollow body (2). <IMAGE>
Patent DE-69732976-T2 (DE)
Inventor: OHMI TADAHIRO
IPC: F16K7/14
Filed: 1997-12-01
Granted: 2006-02-16
Abstract: The invention relates to a fluid control valve which controls a fluid moving through a valve body by means of opening and closing a portion between a valve seat and a valve holder using a drive unit, wherein:  said drive unit comprises a rod shaped shaft for applying pressure via said valve seat and a valve rod, and a member a which is affixed around said rod shaped shaft,  said member a comprises a magnetic material, and  
a coil having a space between it and the shaft and provided at a position parallel to said shaft moves said member a upwardly and downwardly by electromagnetic induction, and using the force of a spring, as well, the portion between said valve seat and said valve holder is opened and closed, and after an exciting current supplied to said coil is cut off, an exciting current is resupplied to said coil for a brief period after a passage of a short time t.
Patent DE-69806591-T2 (DE)
Inventor: DOYLE LAURENCE
IPC: C01B3/00
Filed: 1998-04-30
Granted: 2003-03-27
Abstract: PCT No. PCT/GB98/01272 Sec. 371 Date Jan. 4, 2000 Sec. 102(e) Date Jan. 4, 2000 PCT Filed Apr. 30, 1998 PCT Pub. No. WO98/50968 PCT Pub. Date Nov. 12, 1998A hydrogen storage material comprising hydride-forming metallic particles and an interface activation composition, wherein the surface of at least some of the hydride-forming metallic particles have a discontinuous or partial deposit of said interface activation composition, such as one or more platinum group metals, is disclosed. The hydrogen storage material demonstrates improved kinetic and oxidation parameters over untreated particles.
Patent DE-69807533-T2 (DE)
Inventor: BIRN VALDEMAR
IPC: F16H55/40
Filed: 1998-10-06
Granted: 2003-01-16
Abstract: V-belt pulley comprising an outer rim (2) provided with at least one V-belt groove (7) formed by turning, said groove (7) having a bottom (9) provided with a plurality of radially through-going and circumferentially interspaced openings (8). The pulley is cast with a rim (2) having a radially inwardly facing surface (4) is provided with a plurality of circumferentially interspaced recesses (5) of such a radial depth that the radially through-going openings are formed by the turning thereof.
Patent DE-69808619-T2 (DE)
Inventor: DEL SOLDATO PIERO
IPC: A61K31/5575
Filed: 1998-06-17
Granted: 2003-06-12
Abstract: Compounds of the general formula A-X1-NO2, or their pharmaceutical compositions, wherein A contains a prostaglandin residue, X1 is a bivalent connecting bridge.
Patent DE-69810453-T2 (DE)
Inventor: VAN RIET PETER GASTON NADIA
IPC: A63C5/00
Filed: 1998-02-24
Granted: 2003-10-23
Abstract: A snowboard binding has at least two substantially rigid elements separate from one another and pivotably positioned on opposite lateral sides of an instep zone of a user's boot or footwear. The movable elements include press-on elements to reduce pressure exerted onto the boot by the movable elements. The movable elements are further connected to control elements that permit the movable elements to pivot and cooperate to separately retain a respective side of the instep zone of the boot.
Patent DE-69821647-T2 (DE)
Inventor: SONNENSCHEIN MENASHE
IPC: H04B11/00
Filed: 1998-06-18
Granted: 2004-12-23
Abstract: An underwater modulator-demodulator (modem) apparatus for transmitting and receiving data at a high rate through water, said modem comprising: a) a transmitting section comprising: data source means, comprising digital data to be transmitted through water; serial-to-parallel data processing means, for splitting a serial data into n parallel channels; n-channel modulator means, for receiving data from said n parallel channels and for modulating the same with n pairs of ultrasonic carriers, thereby producing a modulated signal; and hydrophone means, for receiving said modulated signal from said n channel modulator, and for transmitting same into water; and b) a receiving section comprising: hydrophone means, for receiving a modulated signal from the water, and for conveying the same into an RF circuit; RF circuitry, for amplifying and shaping the received modulated signal, and for conveying the same into serial-to-parallel means; serial-to-parallel means, for receiving shaped data from the RF circuit, and for splitting the same into n parallel channels; n-channel demodulator means, for demodulating said shaped signal conveyed to the demodulator from said RF circuit, and for outputting n channels of digital data; and parallel-to-serial means for receiving n parallel channels of outputted data from the demodulator, and for combining the data into serial data.
Patent DE-69822494-T2 (DE)
Inventor: YOSHISATO EISHIN
IPC: C07C68/00
Filed: 1998-08-04
Granted: 2005-01-27
Abstract: Aromatic carbonates can be prepared economically and efficiently by reacting an aromatic hydroxy compound with carbon monoxide and oxygen in the presence of a catalyst wherein a palladium compound is supported on a perovskite-type composite oxide represented by the following formula (1) or (1'): M(1-x)M'xM'' Oy (wherein, M is a group IIIB metal; x is a number of 0 to 1; M' is a metal having an ionic radius of 0.90  ANGSTROM  or more; M'' is Mn, Cr, Co, Fe, Ni or Cu; y is a number of 2.5 to 3.5), or L(1-x)L'xL'' Oy (wherein, L is a group IIA or IVA metal taking a divalent state in the form of an oxide; x is a number of 0 to 1; L' is a metal having an ionic radius of 0.90 ANGSTROM  or more; L'' is a group IVA, IVB, or IIIB metal taking a tetravalent state in the form of an oxide; y is a number of 2.5 to 3.5), and the palladium accounts for 0.01 to 15% of the catalyst by weight. <IMAGE>
Patent DE-69830301-T2 (DE)
Inventor: KAUVAR M
IPC: A61P3/10
Filed: 1998-01-15
Granted: 2006-02-02
Abstract: Methods to identify compounds which have at least one characteristic selected from the group consisting of a composition that (a) modulates the kinase activity of insulin receptor; and/or (b) potentiates the insulin activation of insulin receptor; and/or (c) potentiates the stimulation by insulin of cellular glucose uptake; and/or (d) stimulates the uptake of glucose in cells displaying the insulin receptor; and/or (e) lowers blood glucose in diabetic subjects; and/or (f) stimulates IRS-1 phosphorylation; and/or (g) stimulates PI3 kinase activity; and/or (h) stimulates GLUT-4 translocation; are described. Successful substances having such characteristics alter the conformation of the two-lobed cytoplasmic kinase domain or preferentially bind sites which have been identified as modulator binding sites in the insulin receptor  beta  chain. Also, modulation of the activity of the insulin receptor, enhancement of glucose uptake by cells, and other effects significant in the control and management of diabetes are accomplished using compounds of formula (1), wherein each Ar is independently an aromatic moiety; each A is independently a proton-accepting substituent; each R is independently a noninterfering substituent; m is 0, 1 or 2; n is 1-6; and each linker is independently -CH2-, -N=N-, -CH=CH-, -NHCO-, or -NHCONH- or an isostere thereof, wherein when n is 1, at least one Ar must comprise at least 2 fused aromatic rings. Compounds in the genus of formula (1) can also be used for structure activity studies to identify features responsible for the relevant activities.
Patent DE-69833804-T2 (DE)
Inventor: SIU BERNARD
IPC: G01H9/00
Filed: 1998-12-18
Granted: 2006-10-12
Abstract: A nondestructive bond testing system is implemented using a pulse laser that sends a single or multiple pulse(s) of controlled magnitude and bombards an object of interest causing a thermoelastic excitation response. This excitation in turn induces an ultrasonic propagation along or through the surface material. By detecting, capturing and interpreting these thermoelastic propagation signatures, the attachment condition of the joining materials is determined. The technique is a significant improvement over traditional mechanical pull, shear or contact type techniques. The techniques are implemented in automated high speed inspection systems suitable for real time manufacturing application. Particular applications include evaluating material joining in microelectronics manufacture (such as ball bonds) and thin coating processes.
Patent DE-69903705-T2 (DE)
Inventor: HUPFIELD PETER
IPC: C08G77/06
Filed: 1999-12-01
Granted: 2003-07-03
Abstract: A polymerisation process comprising mixing siloxanes having silicon-bonded groups R' with ionic phosphazene base catalysts and allowing condensation via reaction of Si-R' groups with the formation of a Si-O-Si linkage, R' denoting a hydroxyl group or a hydrocarbonoxy group having up to 8 carbon atoms is claimed. The catalysts may be of the general formulae: <MATH>  or <MATH> in which R<1> is hydrogen or an optionally substituted hydrocarbon group or in which two R<1> groups bonded to the same N atom may be linked to complete a heterocyclic ring, R<2> is hydrogen or an optionally substituted hydrocarbon group, x is 1, 2 or 3, y is 1, 2, 3 or 4 and A is an anion. Also claimed is a process which comprises mixing siloxanes having silicon-bonded groups R' and cyclic or linear siloxanes having no silicon-bonded groups R' with ionic phosphazene base catalysts and allowing the siloxane having silicon-bonded groups R' to condense and the cyclic and linear siloxanes having no silicon-bonded R' groups to polymerise by equilibration.
Patent DE-69904350-T2 (DE)
Inventor: ANDERSSON GUNNAR
IPC: A61J1/20
Filed: 1999-09-21
Granted: 2003-10-09
Abstract: A device for storing and administering a medical fluid comprising a sealed flexible formed container with an opening part in its front end in which an insert is positioned. Over the insert, the container extends into a removable sealing cap. After removal of the sealing cap an injection means is attached to the insert and fluid administration through the insert is admitted in one direction by squeezing the container.
Patent DE-69906061-T2 (DE)
Inventor: CHARI N
IPC: G06F21/12
Filed: 1999-05-25
Granted: 2003-11-06
Abstract: A system and method implemented in an interactive television system for restricting or controlling the access rights of interactive television applications and carousels. The system broadcasts modules from a broadcast station to a plurality of receiving stations, which execute applications containing the modules. In one embodiment, the applications utilize a credential consisting of a producer identification number (ID) and an application ID for each of the grantor and grantee applications, an expiration date, a set of permission data, a producer certificate and a signature. An application requesting access and a carousel granting access may be identified by respective producer and application IDs. The credential utilizes public key encryption to ensure the integrity of the credential. The producer and application IDs may be replaced with wildcards so that rights may be granted to a group of producers or applications.
Patent DE-69907114-T2 (DE)
Inventor: WETTER HERMANN
IPC: B60N2/26
Filed: 1999-11-02
Granted: 2004-02-26
Abstract: The seat portion of a rearward facing child safety seat has static rear part (12) and a movable front part (34) which is movable between a deployed position in which its upper surface is contiguous with that of the rear part (35) and a stowed position leaving an opening (36) in front of the rear part (35) for receiving the legs of an older child (40) occupying the child seat with his knees (42) bent and his feet (44) positioned below the level of the static rear part (35). <IMAGE>   <IMAGE>
Patent DE-69908821-T2 (DE)
Inventor: JOHNSON IAN DAVID
IPC: H04L49/111
Filed: 1999-11-10
Granted: 2004-04-08
Abstract: A data switch for handling packets of information; the switch includes input traffic managers, ingress routers, a memoryless cyclic switch fabric, egress routers and output traffic managers all acting under the control of a switch controller. Each ingress router includes a set of virtual output buffers one for each output traffic manager and each message priority. Each data packet or cell as it arrives is examined to identify the output traffic manager address and its message priority. The switch controller uses a first arbitration and selection process to schedule the passage of the next cell across the switch fabric which the ingress router uses a second arbitration and selection process to select the appropriate virtual output queue for use in the switch fabric transfer.