baber/WOPTO huggingface dataset:
Patent CA-3089949-A1 (CA)
Inventor: BJURSTEN HENRIK
IPC: A61B17/00
Filed: 2019-02-06
Abstract: The present disclosure relates to negative pressure-based gripping system for gripping and retaining a target, preferably a moving target, such as a heart of a human or animal, in a fixed position, comprising: a catheter having a tubular body; a proximal end; and a remotely operable and flexible distal end section with a distal opening; a negative pressure generator, such as a vacuum pump, in connection with the tubular body; and a control unit configured to position the distal end of the catheter, wherein said control unit is further configured to control an operation of the negative pressure generator such that a negative pressure is generated in the tubular body to grip the target by the distal opening of the catheter upon positioning of the distal opening adjacent to the target. The disclosure further relates to method for gripping and retaining a target, preferably a moving target, such as a heart of a human or animal, in a fixed position in relation to the device.
Patent CA-3093273-A1 (CA)
Title: Compositions and methods for treatment of insulin resistance
Inventor: MERALI SALIM
IPC: A61P3/10
Filed: 2019-03-07
Abstract: In certain embodiments, this disclosure relates to methods of treating or preventing type 2 diabetes, pre-diabetes and conditions characterized by an increase in the levels of AIC, glucose, insulin, homeostasis model of assessment of insulin resistance (HOMA-IR), oxidative stress in adipose tissue, and earbonvlation of GLUT4 comprising administering an effective amount of a compound of Formula I-III as described herein, to a subject in need thereof.
Patent CA-3095426-A1 (CA)
Inventor: NAM KIYEAN
IPC: C07D487/04
Filed: 2019-04-11
Abstract: The present invention relates to pyrazolo [1,5 -a] [1,3,5 ]triazine and pyrazolo[1,5-a] pyrimidine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of cell proliferative diseases, inflammatory diseases, immunological diseases, cardiovascular diseases and infectious diseases. Furthermore, the present invention is directed towards pharmaceutical compositions containing at least one of the pyrazo lo [1,5-a][1,3,5 ]triazine and pyrazolo [1,5-a]pyrimidine derivatives and/or pharmaceutically acceptable salts thereof.
Patent CA-3097816-A1 (CA)
Title: Active control system for rolling behaviors of high-speed trains
Inventor: ZHANG CHUNWEI
IPC: B61D49/00
Filed: 2020-11-02
Abstract: The present application relates to vibration control, and more particularly to an active control system for rolling behaviors of high-speed trains. The active control system includes a sensor, a controller and an output device. The output device includes a power unit, an output unit and a casing. The casing includes a bottom plate, an annular side plate and a cover plate, and is further provided with a through hole which penetrates through the bottom plate and the cover plate. The power unit includes a motor and a speed-increasing gear set. The speed-increasing gear set includes a main speed-increasing gear and a secondary speed-increasing gear engaged with each other. The main speed-increasing gear is provided on the motor. The output unit includes a rotation inertia ring, a torque transmission ring and a connecting ring. The connecting ring is fixed on the bottom plate. The rotation inertia ring is fixed to the connecting ring through the torque transmission ring. An outer circumference of the rotation inertia ring is provided with teeth, and the rotation inertia ring engages with the secondary speed-increasing gear through the teeth. The active control system of the invention applies active control torque to the shaking, rolling and nodding of the train body to control the vehicle body.
Patent CA-3102527-A1 (CA)
Inventor: HUSSEY JAMES JOSEPH
IPC: A61P35/00
Filed: 2019-06-04
Abstract: La présente invention concerne une formulation aqueuse pharmaceutique comprenant de la 1-(4-{[4-(diméthylamino)pipéridin-1-yl]carbonyl}phényl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phényl]urée ou un sel d'acide organique ou inorganique pharmaceutiquement acceptable correspondant, un acide organique ou inorganique pharmaceutiquement acceptable, une bêta-cyclodextrine ou une gamma-cyclodextrine pharmaceutiquement acceptable et de l'eau, qui est une solution claire, à condition que l'acide organique ou inorganique (y compris un sel correspondant) ne soit pas un acide sulfonique. Une telle formulation est particulièrement appropriée pour une administration par voie intraveineuse ou parentérale à un patient.
Patent CA-3102917-A1 (CA)
Inventor: HIETANIEMI MATTI
IPC: D21H21/18
Filed: 2019-07-10
Abstract: A method for manufacturing a multi-layered fibrous web, which comprises at least two fibrous layers, wherein each of the layer is formed from one or more fibre stocks, the fibrous layers are combined prior to subjecting the multilayered fibrous web to wet-pressing and drying, and in which method at least one layer of the multi-layered fibrous web is formed from the fibre stock comprising at least 50 weight-% of chemi-thermomechanical pulp (CTMP), hardwood kraft pulp and/or recycled fibre material calculated from the thick stock applied to the particular layer approach system, and to which fibre stock is added a first strength component and a second strength component, wherein the first strength component is a cationic strength agent and the second strength component comprises a synthetic amphoteric polymer composition having a net charge from -3 to +1 meq/g (dry), at pH 7.
Patent CA-3103560-A1 (CA)
Title: Prediction d'evenement de risque cardio-vasculaire et leurs utilisations
Inventor: STERLING DAVID
IPC: G16B40/30
Filed: 2014-11-03
Abstract: Abrégé : Il est décrit des méthodes et méthodes informatiques servant à évaluer une personne en vue de prévoir son risque de souffrir un événement cardiaque au cours dune période dun an à cinq ans. Dans le cadre des méthodes en question, on sélectionne au moins deux biomarqueurs parmi le complément C7 dangiopoiétine-2 1VIMP12, la troponine cardiaque I, la protéine 4 liée à langiopoiétine, le complexe CCL18/PARC alpha 1-antichymotrypsine, lalpha-2-antiplasmine GDF11 et le GDF11 combiné avec le FSTL3. Les méthodes en question sont particulièrement utiles pour ce qui est de prévoir les événements cardiaques chez les patients atteints, et chez les patientes atteintes, de coronaropathie. Date reçue / Date Received 2020-12-22
Patent CA-3105948-A1 (CA)
Inventor: HAN CHUNG DEAN
IPC: G06T9/00
Filed: 2019-07-10
Abstract: In a three-dimensional data encoding method, a bitstream is generated by encoding a plurality of sub-spaces in a target space that comprises a plurality of three-dimensional points, the bitstream comprising a plurality of encoded data corresponding to the plurality of sub-spaces. In generating the bitstream, a list of information about the plurality of sub-spaces, which are mapped to a plurality of identifiers allocated to the plurality of sub-spaces, is stored in first control information shared by the plurality of encoded data in the bitstream (S4531), and the identifiers, allocated to the sub-spaces that correspond to the encoded data, are stored in each of the headers of each of said plurality of encoded data (S4532).
Patent CA-3109569-A1 (CA)
Title: Method and apparatus for hybrid event service
Inventor: SOURA KEITH
IPC: H04N9/80
Filed: 2019-07-15
Abstract: The system provides an event driven system that sits between the enterprise ecosystem and the client system. The system creates a bridge between systems that produce actionable information and systems that consume events related to that information. It coordinates data-change events between those internal microservices for the client, providing a simple, well-typed interface for change events that may drive downstream actions in a consuming service. In one embodiment, the system can intercept those messages, decorate them with client-specific configuration data, and send them to the appropriate downstream client systems, all the while tracking the state of events to provide an auditable window into the system. Events are designed to help an appropriately credential ed and authorized consuming system dynamically call the enterprise's API resources in post-processing by providing relative linking as an out-of-the-box attribute of the event messages.
Patent CA-3110000-A1 (CA)
Inventor: GENSCH WALDEMAR
IPC: B65G61/00
Filed: 2019-08-15
Abstract: The invention relates to a palletising device (10) comprising: a compressing device (60), which has a peripheral, closed frame (70), there being on the frame (70) at least one slide (61, 62, 63, 64) which is movable in a horizontal direction; and a setting-down device (50) which defines a transporting face (53) for transporting layers of articles (15). The frame (70) surrounds an opening (67) which passes through in a vertical direction (Z), and the setting-down device (50) is movable in the longitudinal direction (X) relative to the compressing device (60) between a first longitudinal position, in which the transporting face (53) is offset in a longitudinal direction (X) from the frame (70), and a second longitudinal position, in which a projection of the through opening (67) in the vertical direction (Z) meets the transporting face (53).The compressing device (60) and the setting-down device (50) are arranged on a lifting device (20) such that they can move in the vertical direction (Z).The invention also relates to a method for operating a palletising device (10) according to the invention, said method comprising several steps.
Patent CA-3113839-A1 (CA)
Title: Method and system for enhancing a user interface for a web application
Inventor: MYERS CHRISTOPHER M
IPC: G06F9/44
Filed: 2019-11-19
Abstract: A computer system for testing a user interface (UI) includes a test execution module and an analysis module. The analysis module is configured to (i) analyze a state of the UI, (ii) in response to determining that the state satisfies criteria for a goal associated with the UI, output a success indicator, and (iii) in response to determining that the state does not satisfy the criteria, output a set of actions. The test execution module is configured to, in response to the output being the set of actions: execute an action from the set of actions; update a test distance, and supplement test data. The test execution module is further configured to (i) in response to the output being the success indicator, store the test distance and the test data in a collection of completed tests and (ii) determine a shortest path to the goal in the UI.
Patent CA-3115783-A1 (CA)
Title: Azeotrope or azeotrope-like compositions of trifluoroiodomethane (cf3i) and 1,1,1,2,2,3,3,-heptafluoropropane (hfc-227ca)
Inventor: JUNGONG CHRISTIAN
IPC: C09K5/04
Filed: 2019-10-10
Abstract: The present disclosure provides azeotrope or azeotrope-like compositions including trifluoroiodomethane (CF3I) and 1,1,1,2,2,3,3-heptafluoropropane (HFC-227ca), and a method of forming an azeotrope or azeotrope-like composition comprising the step of combining 1,1,1,2,2,3,3-heptafluoropropane (HFC-227ca) and trifluoroiodomethane (CF3I) to form an azeotrope or azeotrope-like comprising 1,1,1,2,2,3,3-heptafluoropropane (HFC-227ca) and trifluoroiodomethane (CF3I) having a boiling point of about -24.46oC 0.30oC at a pressure of about 14.40 psia 0.30 psia.
Patent CA-3116266-A1 (CA)
Title: Blood clot removal device, system, and method
Inventor: FORSELL PETER
IPC: A61M60/888
Filed: 2009-01-28
Abstract: ABSTRACT A blood clot removal device for removing blood clots from the vascular system of a patient is implantable in the patient's body. The blood clot removal device comprises a blood flow passageway to be connected to the patient's vascular system to allow circulation of the patient's blood through the blood flow passageway, a filter provided in the blood flow passageway for collecting blood clots occurring in the blood flowing through the blood flow passageway, and a cleaning device for moving blood clots collected by the filter out of the blood flow passageway. By means of such blood clot removal device, the risk of blood clots reaching sensitive areas of the patient's body, such as the brain, is reduced. Date Recue/Date Received 2021-04-23
Patent CA-3118024-A1 (CA)
Title: Handling of pre-formed fabrics
Inventor: BERTIN ANDRE
IPC: B29C49/42
Filed: 2018-11-12
Abstract: A support (100) for handling pre-formed woven fabric layers to be used for conical shell composite components or segments is described. The support comprises a shaped portion (120) having a plurality of peaks (170) and a plurality of troughs (180) extending between first and second longitudinal edges (130, 140). Each peak has a varying amplitude along its extent and is configured to maintain warp and weft fibres of the pre-formed woven fabric layers perpendicular to one another. A clamping member may be used to retain a stack of pre-formed woven fabric layers in place on the support. The support may also be used for forming non-woven fibre layers and stacks formed from such non-woven fibre layers, and, for the subsequent handling thereof.
Patent CA-3121330-A1 (CA)
Title: Apparatus with multi-stage cross flow membrane filtration
Inventor: JOHANSEN ULRIK
IPC: B01D61/18
Filed: 2019-12-10
Abstract: The present invention relates to an apparatus and a method for cross-flow membrane filtration which may be used for filtration processes requiring a controllable low Transmembrane Pressure (TMP) and at the same time a controllable high cross-flow. This may be the case both for microfiltration and for ultrafiltration processes. Particularly, the apparatus is directed to use in preparation of food ingredients where fractionating is required. An apparatus comprises a plurality of n membrane modules (2,..., n) and a pump, where the membrane module (1) positioned immediately downstream of the pump is named the first membrane module (1a), each membrane module (1) comprises at least one membrane element (4), one inlet (2) for fluid feed and one outlet (3) for fluid feed, one outlet for permeate (6), and a back-pressure control means (9) such as a valve configured to control the pressure and/or the flow at the outlet for permeate (6), each membrane element (4) has a central opening (5) configured to collect permeate and direct the permeate to the outlet for permeate (6), which outlet for permeate (6) is positioned at the same end of the membrane module (1) as the outlet (3) for fluid feed providing concurrent flows in fluid feed and permeate in full length of each membrane module (1). The outlet (3) for fluid feed of the first membrane module (1a) is connected to the fluid inlet (2) of the second membrane module (1b), and if further membrane module(s) is/are present, the outlet (3) for fluid feed of a previous membrane module (n-1) is connected to the fluid inlet (2) of a following membrane module (n), and for the last membrane module (n), the outlet (3) for fluid feed is connected to the fluid inlet (2) for fluid feed of the first membrane module (1a). A method comprises the following steps a), b) and c): a) An amount of fluid feed is continuously pumped with pressure PB through a loop comprising a multiplicity of n membrane modules which modules are serially connected, the fluid feed and permeate flow concurrently through each of the n membrane module(s), b) generated permeate is continuously drained from each membrane module through a permeate outlet, c) the permeate pressure at the permeate outlet of each membrane module is controlled keeping TMP within a desired range.
Patent CA-3121620-A1 (CA)
Title: Compositions and methods for the treatment of liver disorders
Inventor: LIAN BRIAN
IPC: A61K31/192
Filed: 2019-12-04
Abstract: The present disclosure is directed toward the use of thyroid receptor agonists of pharmaceutically acceptable salts thereof, in combination with a second pharmaceutical agent for preventing, treating, or ameliorating fatty liver diseases such as steatosis, non-alcoholic fatty liver disease, and non-alcoholic steatohepatitis.
Patent CA-3124344-A1 (CA)
Title: Quint-focal diffractive intraocular lens
Inventor: LIU YUEAI
IPC: G02B5/18
Filed: 2020-02-20
Abstract: A diffractive quint focal intraocular lens includes a base optic and a diffractive element. The base optic has a base curvature that corresponds to a base power. The diffractive element provides constructive interference in at least five consecutive diffractive orders to create a set of five focal points for vision from near to distance. The constructive interference provides for a near focal point at the highest diffractive order of the five consecutive diffractive orders, a distance focal point at the lowest diffractive order, and three intermediate diffractive orders between the highest and lowest diffractive orders to provide continuity of vision from near to distance with an extended intermediate, an intermediate, and an extended near focal points. The multifocal intraocular lens (i) provides a diffraction efficiency of -100%, (ii) creates almost no positive optical disturbance, (iii) may also reduce longitudinal chromatic aberration.
Patent CA-3125855-A1 (CA)
Inventor: KIM KI HYUN
IPC: C07K19/00
Filed: 2021-04-16
Abstract: Abstract Disclosed herein are an anti-HER2 affibody and a switch molecule including a cotinine-conjugated anti-HER2 affibody. When applied in combination with Cot-sCART, the cotinine-conjugated anti-HER2 affibody reacts with HER2-positive cells to induce immune cell activity, thereby finding advantageous applications as switch molecules in sCART therapeutic agents. Date Recue/Date Received 2021-07-23
Patent CA-3127578-A1 (CA)
Inventor: BESSON NICOLAS
IPC: A61M5/315
Filed: 2020-02-26
Abstract: L'invention concerne un dispositif d'administration de médicament comprenant un boîtier, un ensemble seringue comprenant un cylindre, un bouchon et une canule, au moins une partie de l'ensemble seringue étant positionnée à l'intérieur du boîtier, et un ensemble d'entraînement comprenant un corps de piston conçu pour déplacer le bouchon à l'intérieur du cylindre lors de l'actionnement de l'ensemble d'entraînement, au moins une partie de l'ensemble d'entraînement étant positionnée à l'intérieur du boîtier. Le corps de piston possède une position de pré-utilisation avant le déplacement du corps de piston, une position d'injection dans laquelle le corps de piston déplace le bouchon à l'intérieur du cylindre et une position de post-utilisation dans laquelle le déplacement du corps de piston s'est arrêté. Le dispositif comprend en outre un élément indicateur audio conçu pour émettre une indication audible d'une transition du corps de piston à partir de la position d'injection vers la position de post-utilisation.
Patent CA-3128388-A1 (CA)
Inventor: WILLS KEVIN MICHAEL
IPC: A61F2/30
Filed: 2020-02-06
Abstract: L'invention concerne une doublure d'essai acétabulaire (12) ayant une première extrémité fermée (19), une seconde extrémité ouverte (18), et une paroi de doublure (54) ayant un bord périphérique distal (24). La paroi de doublure acétabulaire peut comprendre une surface intérieure (26), une surface extérieure (57) configurée pour être logée à l'intérieur d'une coque acétabulaire (10), une première découpe (34A) à travers la paroi de doublure, une seconde découpe (34B) parallèle à la première découpe, à travers la paroi de doublure, et une troisième découpe (38) dans la surface intérieure, partiellement à travers la paroi de doublure, la troisième découpe s'étendant entre les première et deuxième découpes, et au moins une languette mobile (22) partant du bord périphérique vers l'intérieur et vers un centre axial (A) de la doublure et ayant des parois latérales (36) définies par l'un des ensembles de découpes, la languette comprenant au moins une saillie (28, 29) sur une surface extérieure de la languette configurée pour être fixée de manière amovible à une partie d'une coque acétabulaire.
Patent CA-3129319-A1 (CA)
Title: Method for calculating the strength and the service life of a process apparatus through which fluid flows
Inventor: STEINBAUER MANFRED
IPC: F28D9/00
Filed: 2019-09-11
Abstract: The invention relates to a method for calculating the strength and the service life of a process apparatus through which fluid flows, wherein: temperatures existing at a plurality of different points of the apparatus are measured at a first time point in order to obtain temperature measurement values (201); the temperature measurement values are used as constraints in a finite element method (203) in order to determine mechanical stresses existing at a plurality of different points in the material of the apparatus as stress values (204); the remaining service life of the material of the apparatus is determined from the obtained stress values (205); the remaining service life of the material of the apparatus is determined also in dependence on data regarding the apparatus that were determined at a second time point (207), which second time point is earlier than the first time point.
Patent CA-3132465-A1 (CA)
Inventor: MUANCHART MANKAEW
IPC: A01G31/02
Filed: 2020-01-29
Abstract: Un équipement et un procédé pour la nutrition des plantes par l'intermédiaire de l'air sont mélangés entre un système aéroponique et un système hydroponique par brumisation. L'équipement injecte la nutrition des plantes par l'intermédiaire d'un système aéroponique rythmique avec un système de commande automatique. L'équipement permet aux plantes de recevoir des nutriments de tailles différentes en même temps et de façon constante, combinés à une nutrition à base de colloïde pour plante par l'intermédiaire du système hydroponique par brumisation. La présente invention permet de réduire l'énergie et les ressources pour la culture et de réduire la main-d'uvre dans l'agro-industrie.
Patent CA-3136282-A1 (CA)
Title: Module de suivi d'injection
Inventor: MARCOZ ALAIN
IPC: A61M5/24
Filed: 2020-01-09
Abstract: La présente invention concerne un module de suivi d'injection adapté et conçu pour être fixé de manière amovible à une extrémité proximale d'un système stylo d'injection pour l'administration d'un médicament. Le module de suivi comprend un corps principal creux adapté et conçu pour être monté de manière coaxiale sur, et s'engager en co-rotation avec, une roue de paramétrage de dose du système d'injection par stylo, et un trou longitudinal central ayant une extrémité proximale et une extrémité distale et un système de suivi d'injection localisé dans le trou à son extrémité proximale. Un système de suivi d'injection est mobile à l'intérieur du trou le long de son axe longitudinal central depuis une première position de suivi dans laquelle le système de suivi d'injection ne se trouve pas en contact de butée avec une surface proximale d'un activateur d'injection du système stylo d'injection, vers une seconde position de suivi dans laquelle le système de suivi d'injection se trouve en contact de butée avec la surface proximale de l'activateur d'injection.
Patent CA-3136969-A1 (CA)
Title: Fusion polypeptide comprising fc region of immunoglobulin and gdf15
Inventor: KIM YEONCHUL
IPC: A61P1/16
Filed: 2020-04-22
Abstract: Disclosed are: a fusion polypeptide comprising growth/differentiation factor 15 (GDF15) and an Fc region of an immunoglobulin; a pharmaceutical composition comprising the fusion polypeptide; and a method for increasing the in vivo duration of GDF15, the method comprising a step for fusing an Fc region of an immunoglobulin.