baber/WOPTO huggingface dataset:
Patent BG-103842-A (BG)
Title: 5,7-disubstituted 4-aminopyrido [2,3-d]pyrimidine compounds and their application as adenosinekinase inhibitors
Inventor: BHAGWAT SHRIPAD S
IPC: C07D471/04
Filed: 1999-10-29
Abstract: The method of adenosinekinase inhibition includes the application of a compound with the formula where R1 & R2, separately, are selected from H, lower alkyl, C1-C6 alkoxyC1-C6 alkyl, arylC1-C6 alkyl, -C(O)C1-C6 alkyl, -C(O)aryl, -C(O)heterocyclyl, or can be bound together with the nitrogen to which they are attached forming 5-7-member ring optionally containing 1-2 additional heteoratoms selected from O, N or S, R3 is of the group including lower alkyl, lower alkenyl, lower alkynyl, cycloalkyl, aryl, arylalkyl, heteroaryl, heterocyclic group, heteroarylalkyl or heterocycloalkyl where the heteroaryl or the heterocyclic group are directly or indirectly bound by a ring carbon atom, R4 is from the group including lower alkyl, lower alkenyl, lower alkynyl, cycloalkyl, aryl, arylalkyl, heteroaryl, heterocyclic group, heteroarylalkyl or heteorcycloalkyl, and the pinctured line --- means optional presence of a double bond provided that the suitable valencies are preserved. The invention also relates to a pharmaceutical composition containing therapeutically effective quantity of the compound in a combination with a pharmaceutically acceptable carrier, to a method for the treatment of cerebral ischaemia, epilepsy, pain killing, inflammation and sepsis in mammals where therapeutically effective quantity of the compound is administered, and to a method for the preparation of the above compounds and compounds with formula I. 19 claims
Patent BG-105142-A (BG)
Title: Oxazolidinones to treat eye infections
Inventor: COCHRAN ROBERT
IPC: A61P31/04
Filed: 2001-01-10
Abstract: The present invention involves a method of treating an ophthalmic infection in an useful warm blooded mammal who is in need of such treatment which comprises topical administration of an ophthalmologically effective amount of oxazolidinone. 17 claims
Patent BG-105497-A (BG)
Title: Device for metering and monitoring the consumption of active electric power
Inventor: KISHKILOV ORLIN V
IPC: G01R21/133
Filed: 2001-05-08
Abstract: The device comprises a metering unit (1), one of the outputs (2) of which is coupled to a calculation and control unit (3), coupled two-way to a unit for light and digital indication (4) and a unit for cutting off the supply of electric power to the user (5). Unit (1) has a second output (6) for a signal for wrong connection of the electric meter, and a third output (7) for a signal for the presence of mains voltage. These two outputs are connected to the respective inputs of the calculation and control unit (3), to which a unit for energy independent memory (8) is two-way connected, units (1 and 5) are connected in series to the mains phase. The device can also include a unit for internal switching of billing rates (10), a unit for external switching of billing rates (11), and supply unit (12), as well as a transceiver unit (13), connected by means of an input-output line (15) to a central dispatcher point (16), or to a mobile operator-bills collector. 5 claims, 1 figure
Patent BG-106505-A (BG)
Title: Fungicides
Inventor: DEATH NORMAN J
IPC: A01N47/12
Filed: 2002-03-11
Abstract: The invention relates to a new fingicidally active compound of formula a method of combating fungi at a locus infested or liable to be infested therewith, and an agricultural composition where X is H or O-A+ and A is a radical 1 claim
Patent BG-112066-A (BG)
Title: A method for heat absorption using solar energy through a central heating system
Inventor: KOSTADINOV MIHAIL
IPC: F03G6/00
Filed: 2015-07-29
Abstract: The proposed method for heat utilization from solar energy via a central power plant allows for transference of heat from solar energy, gathered from sun collectors in a single building to a secondary building where that heat is to be used. For this purpose, the buildings must be connected via a pipe network fitted for carrying heat energy. In large cities where central heating is used- TPP- this method can be applied by using a network of pipes and heat stream management systems. Such operators, responsible for management, are the given district heating distribution companies. The so collected solar energy in a single building can be transferred to a second building where it can be used for heating water or central heating. Not only can central heating networks gather energy by placing panels on buildings, but also sun collectors can be placed in specially configured solar parks, which have the purpose of solar energy collectors.
Patent CN-1305709-A (CN)
Title: 锚头蚤、中华蚤、水蛛等防治药剂的制备方法
Inventor: LIN BIRUN
IPC: A01N43/90
Filed: 2000-12-28
Abstract: 本发明是锚头蚤、中华蚤、水蛛等防治药剂的制备方法,其重量百分配方比为:阿维菌素:0.1～2、增效剂:1～5、表面活性剂:5～25、有机溶剂:78～93.9;其制备方法是把阿维菌素及增效剂与所选用表面活性剂置于反应釜中,在一温度、反应釜转速条件下反应一定时间,再加入所选用有机溶剂继续搅匀反应一定时间,便制得本发明药剂,本发明药剂使用安全、对鱼无药害、持效期长、不污染环境、对鱼类的寄生虫杀灭力强,有利于水产业的稳产、高产。
Patent CN-1342075-A (CN)
Title: 脂质体制剂
Inventor: JIRO FUJISAKI
IPC: A61K31/7042
Filed: 2000-03-10
Abstract: 本发明提供一种含2－哌啶酸衍生物的脂质体制剂,该制剂具有能处理诸如脑梗塞等紧急情况的优异的快速作用。一种脂质体制剂,其特征是含有包封在脂质体内的本说明书所述2－哌啶酸衍生物或其可药用盐作为活性组分,其中卵磷脂主要是作为形成脂质体的类脂,该脂质体制剂不含胆固醇作为稳定剂。
Patent CN-1346700-A (CN)
Title: 助催化多金属氧化物催化剂
Inventor: CHATWITEY S
IPC: C07C57/05
Filed: 2001-09-27
Abstract: 一种包含助催化混合金属氧化物的催化剂用于将烷烃或烷烃与烯烃的混合物气相氧化成不饱和羧酸,和用于将烷烃或烷烃与烯烃的混合物气相氨氧化成不饱和腈。
Patent CN-1618040-A (CN)
Inventor: BLEES MARTIN H
IPC: B41K1/50
Filed: 2001-11-16
Abstract: 在平版印刷工艺中例如形成一层表面图案的本发明印模(10)包括一印模体(1)，该印模体有第一面(11)和第二面(12)，第一面(11)上有印刷面(2)，第二面(12)上相叠有载体(4)和液槽(3)。载体(4)中有通道(5)，使得液体从液槽(3)经印模体(1)传送到印刷面(2)上。该印模可制作成一圆筒，以连续进行平版印刷过程。该过程可得到微米或亚微米级的图案。该印模(10)还可装在一更大设备中。
Patent CN-1396686-A (CN)
Title: 面发光半导体激光器的制造方法及采用该激光器的传感器
Inventor: KOKKI MORI
IPC: G11B7/126
Filed: 2002-01-18
Abstract: 带光检测部的面发光式半导体激光器的制造方法及采用该激光器的传感器。在半导体基板上的第1第2区域上，叠层形成第1和第2导电型半导体层。第1区域中第2导电型半导体层上形成与基板垂直发出光的光谐振器。第2区域中用第1第2导电型半导体层构成光电二极管。第1区域中第2导电型半导体层厚1μm以上并用作向光谐振器注入电流的下部电极。构成光电二极管的第2导电型半导体层，在刻蚀后厚度不足1μm。
Patent CN-1414799-A (CN)
Title: 移动通信双频段室内信号光纤分布系统
Inventor: CHEN JIANBIN
IPC: H04B10/25
Filed: 2002-09-21
Abstract: 本发明涉及一种移动通信双频段室内信号光纤分布系统，该发明将移动通信双频段信号送入同一直放机进行功率放大、同频转发，在天线端口实现双频段的信号覆盖，节省直放机、馈线和天线等资源50％。采用光纤传输，衰减小、频带宽、抗电磁干扰，同射频电缆相比，安装方便，特别适用于高层建筑室内双频信号的覆盖。
Patent CN-1405136-A (CN)
Title: 3取代5，6，7，8四氢－4a，8a甲叉－2－酮萘、合成方法及其用途
Inventor: TIAN WEISHENG
IPC: C07C49/737
Filed: 2002-11-05
Abstract: 本发明涉及一种3取代5，6，7，8四氢－4a，8a甲叉－2－酮萘化合物、合成方法和用途。该化合物具有的结构式Ⅰ不仅合成方法简便，适合工业化生产，而且能用于合成结构式为Ⅱ的海洋天然产物spiniferin－1的二氢衍生物(±)dihydrospiniferin－1。
Patent CN-1419160-A (CN)
Title: 幕帘式快门装置
Inventor: SHUJI ICHINOSE
IPC: G03B9/40
Filed: 2002-10-24
Abstract: 一种幕帘式快门装置，具有遮光性的叶片(1)、安装在叶片(1)上的铆销(2)和相对该铆销(2)可滑动卡合并使叶片(1)作开闭动作的臂(5)，铆销(2)的表面硬度比臂(5)的表面硬度硬，具体地说，臂(5)的表面硬度是Hv300～600，铆销(2)的表面硬度是Hv450～1000，在臂(5)和铆销(2)上实施化学研磨处理，而在铆销(2)上镀镍、镀铬、镀钯或镀铑。铆销(2)和臂(5)的材料硬度打字相同，或铆销(2)的材料硬度较硬，此时在铆销(2)或臂(5)上也可镀金。
Patent CN-1549765-A (CN)
Inventor: TOSHIAKI MIYANAGA
IPC: B29B17/04
Filed: 2002-09-02
Abstract: 本发明涉及对在废弃的电视机壳体等上使用的难燃性塑料成形品进行处理，作为再生难燃性塑料再使用的方法。本发明的难燃性塑料的再生处理方法是将从包含难燃性塑料成形品的废弃物回收的难燃性塑料成形品进行破碎处理，并对获得的破碎物进行表面磨削处理，切去其表层部3～30重量％。表面磨削处理可以采用使粉碎物彼此以及/或者使粉碎物与器壁撞击，切去表层部的干式清洗处理。此方法获得的再生难燃性塑料可以单独使用或者将该再生难燃性塑料与同种或不同种的未用的难燃性塑料以5～95∶95～5的重量比混合使用，按UL标准满足V－0或V－2等级。
Patent CN-1589287-A (CN)
Title: 改进的烯烃聚合方法
Inventor: KAYE JOHNSON LYNDA
IPC: C08F210/00
Filed: 2002-11-15
Abstract: 通过在聚合反应中加入硅化合物，该硅化合物中在硅原子上键合有至少一个族15或者16元素的原子，改进了使用族8、9或者10过渡金属与二齿配位体的配合物作为部分聚合催化剂的烯烃聚合反应。该聚合反应通常具有提高的聚合物产率和/或该聚合催化剂具有较长的半寿期。
Patent CN-1698185-A (CN)
Inventor: TERUHIKO TOGAWA TETSUJI NABEYA
IPC: B24B37/005
Filed: 2002-12-06
Abstract: 本涉及一种在研磨半导体晶片等基板后进行平坦化的抛光装置中保持该基板(W)并按压在研磨面上的基板保持装置。本发明的基板保持装置具备内部具有容纳空间的顶圈(topring)主体(2)、和可在顶圈主体的容纳空间内上下运动的上下运动部件(206)，在上下运动部件的下表面上装配具备弹性膜的相接部件(209)，相接部件的弹性膜(291)具备在具有向外凸出的外延凸缘(291a)的同时直接或间接相接于基板的相接部(291b)：和从相接部的外延凸缘基部(291d)向上延伸并连接于上下运动部件的连接部(291c)，连接部由比相接部更富伸缩性的材质形成。
Patent CN-1521987-A (CN)
Inventor: SHAO YONGQIANG
IPC: H04L12/24
Filed: 2003-01-28
Abstract: 本发明公开了一种网络管理系统操作的实现方法，该方法包括：1)在网络管理系统中为链路或节点设置自动显示属性标识；2)在网络管理系统的网络拓扑图上，当定位在任意一条链路或任意一个节点图标时，系统根据自动显示属性标识值判断当前所定位链路或节点是否需要自动显示属性，如果是，则显示该链路或节点属性，进入步骤3)，否则结束；3)直接通过当前所显示的属性进入属性配置界面进行后续操作。本发明的实现方法简化了配置和维护的操作步骤，能够在紧急情况下迅速进行处理，尽可能地减少系统维护带来的时间延误。
Patent CN-1434315-A (CN)
Title: 能够防止光波导元件偏心的光波导配件及其制造方法
Inventor: AKIHIKO SAKAMOTO
IPC: G02B6/24
Filed: 2003-01-24
Abstract: 一光波导元件被插入一管状元件。所述管状元件通过加热被拉长，并且被熔接到所述光波导元件上，因而，可获得一形成体。所述形成体被切割成预定长度，以获得一光波导元件。至少在所述形成体的状态下，管状元件优选地是由其中淀积有晶体的结晶玻璃制成的。
Patent CN-1536709-A (CN)
Inventor: ZHONG SHIZHONG
IPC: H01Q5/10
Filed: 2003-04-09
Abstract: 一种双频倒F型天线，包括制作印刷电路板的底材基板，和形成于基板表面的接地金属层、蜗形金属结构、短路接脚、馈电接脚和终端微带。其中蜗形金属结构更具有一短路端与一开路端，且短路接脚与接地金属层电性连接。此外，由蜗形金属结构的适当位置处向外沿伸，连接至馈电电路，而具有调整匹配阻抗作用的终端微带是制作于基板上，并通过导电贯孔连接蜗形金属结构的开路端。藉由调整蜗形金属结构的螺线圈数，增加天线另一可使用的频段。
Patent CN-1526721-A (CN)
Inventor: ZHOU TAO
IPC: A61P15/12
Filed: 2003-03-06
Abstract: 本发明涉及一种利用含亚砜基的极性吸附树脂从孕马尿中提取雌性激素的方法，在树脂洗脱过程采用淋萃洗脱。含有亚砜基的极性吸附树脂和淋萃洗脱相结合有助于，提高对雌性激素的选择性吸附和解析，以及提高雌性激素的回收率。该方法工艺简单，成本低，有利于工业化生产。
Patent CN-1601942-A (CN)
Inventor: QIU HUA
IPC: H04W52/54
Filed: 2003-09-28
Abstract: 本发明有关一种传输格式组合选择平滑处理方法，适用于WCDMA RNC系统中码组合传输信道。该方法包括：先对信令信道进行传输格式的选择；再对非BE信道进行传输格式选择；最后对BE信道进行传输格式选择。在对BE信道进行传输格式选择时，根据用户业务量的突发状态，对信道的传输格式进行限速处理，减缓功率的变化幅度，满足RNC系统对功率的需求。
Patent CN-1517760-A (CN)
Inventor: CHIN-SEUNG CHO
IPC: G02F1/13357
Filed: 2003-05-23
Abstract: 一种背光单元，包括一个发光的点状光源和一个包括有全息图案的光导板，所述全息图案形成为同心圆形状，其中心位于点状光源处。因此，由于可以使得入射到全息图案上的光线的入射方位角恒定，从而可以提高穿过光射出表面射出的光的效率。还有，由于可以使得射出光线的射出方位角的分布范围均匀，所以可以从光射出表面获得均匀的亮度。
Patent CN-1503252-A (CN)
Inventor: JONG-CHIN LEE
IPC: G11B19/12
Filed: 2003-05-30
Abstract: 提供了一种用于考虑盘不平衡来判别盘的类型的方法和装置。该方法包括如下步骤：停止用于使盘旋转的马达的操作；使用在对盘的聚焦操作期间发生反射光和聚焦误差信号，探测与从盘的表面到数据记录层的距离对应的时间；以及通过比较所探测到的时间和参考值，在CD类型和DVD类型之间判别盘的类型。因此，有可能减少因插入盘驱动器的盘的不平衡而导致的盘类型判别错误。
Patent CN-1557015-A (CN)
Inventor: AKIRA KUIBIRA
IPC: H01L21/687
Filed: 2003-03-06
Abstract: 一种半导体制造用保持体，被设置在接受反应气体的处理室内，该半导体制造装置用保持体具有：将被处理物10保持在表面的同时具备用于对被处理物进行加热的电阻发热体2的陶瓷制保持体1、和一端在被处理物保持表面以外的部位支持该陶瓷制保持体1而另一端被固定在处理室上的支持构件6，且设置在该陶瓷制保持体1的被处理物保持表面以外的部位的电阻发热体2的电极端子3以及引出线4被收容在绝缘管5内。根据本发明提供用于对埋设在保持体内的电阻发热体供电的电极端子以及引出线不会发生漏电和打火并且在保持体中可以获得±1.0％以内的均热性的半导体制造装置用保持体。
Patent CN-1691919-A (CN)
Inventor: JEAN-CHARLES LEHEUC
IPC: A61B17/70
Filed: 2003-07-14
Abstract: 一种用于固定一个骨节段的板系统，所述板系统包含一个可啮合到至少第一和第二骨成分的板。用于脊柱固定时，板至少连接到第一和第二椎骨且每个椎骨中至少使用一个骨紧固件。锁紧件连接到板以防止骨紧固件从板上脱落。一种锁紧件是可变锁紧件，允许骨紧固件无冲突地栓牢在板中。第二种锁紧件是一个固定锁紧件，相对板固定骨紧固件。
Patent CN-1681965-A (CN)
Inventor: YOSHINORI MARUMO
IPC: H01L21/288
Filed: 2003-05-23
Abstract: 通过使保持于基板保持部上的基板和板的间隔接近，从处理液喷出部喷出处理液，可以对基板进行无电解镀。由于处理液流过基板和板之间的间隙，所以在基板上产生处理液流，可以向基板上供给新鲜的处理液。其结果，即使在处理液为少量的情况下，也能在基板上形成均匀性良好的镀膜。
Patent CN-86107651-A (CN)
IPC: G01N23/20
Filed: 1986-11-08
Abstract: 一种新型而独特的测角仪在此提出，它用于利用X射线测定样品的角度位置，其测量精度在0.0001°以上，且不会产生位移。该装置为无级可调且稳定。
Patent CN-88101192-A (CN)
IPC: A01F11/06
Filed: 1988-02-03
Abstract: 本发明涉及一种玉米脱粒机，它包括：至少一对滚筒和副滚筒(凹板)。副滚筒由一个可调部分和一个不可调部分组成。本发明的玉米脱粒机具有调节滚筒与副滚筒之间间隙的调节机构。本发明的装置的优点是：使用这种结构的副滚筒，大量节省金属，并提高了筛选能力和整机的生产效率。由于出口可在较宽的范围内调整，脱粒机可适用于具有不同湿度和尺寸的玉米棒而不会损伤谷物。假如异物进入脱粒机，由于预设的安全凹板自动打开，从而可防止滚筒和副滚筒变形。
Patent CN-1040218-A (CN)
Inventor: GUOZHI XUE
IPC: C11B3/06
Filed: 1988-08-04
Abstract: 本发明涉及一种蓖麻油的精炼工艺，主要是用氢氧化钠碱炼毛油，以中和掉毛油中的游离酸，用沸水连续洗涤碱炼过的毛油，真空脱水，然后用酸性白土和活性炭脱色，最后过滤而得到成品油。
Patent CN-1042672-A (CN)
Title: 集装箱清洗工艺及设备
Inventor: HAOTAO XIE
IPC: B08B1/00
Filed: 1988-11-15
Abstract: 一种集装箱清洗技术，特别是适用于集装箱集散地，例如港口集中清洗集装箱，本技术包括三个步骤。首先将集装箱按污染物性质分类；再将同类污染物集中处理：先将废物，渣清理集中处理，再用水洗箱体；最后处理洗箱废水，采用通用的废水处理系统利用不同的处理工艺分别处理各类废水。本发明还可用于清洗散装船的货仓，也不产生二次污染。
Patent CN-1047067-A (CN)
Inventor: RUDONG YANG
IPC: C01B33/32
Filed: 1989-05-09
Abstract: 本发明为工业生产九水偏硅酸钠提供了一种新方法，其特点是以无水芒硝(无明粉)代替了传统生产九水偏硅酸钠方法中所用的Na 2 CO 3 和NaOH并由两步法变为一步法，工艺简单，原料易得，价格低廉，从而大幅度降低了生产成本，是一种可靠的实用技术。
Patent CN-1039920-A (CN)
Inventor: MAEDA YOSHIHITO
IPC: G11B7/0055
Filed: 1989-06-24
Abstract: 本发明提供了一种采用非晶态－晶态相变进行记录和擦除的光记录介质，其中记录膜结构的光学记录介质处于非晶态时的反射率大于记录膜结构的光学记录介质处于晶态时的反射率，或者记录膜结构的光学记录介质处于非晶态时的吸收率小于记录膜结构的光学记录介质处于晶态时的吸收率。
Patent CN-1054492-A (CN)
Title: 具有涂层台的固体仿形装置和方法
Inventor: CHAPMAN BRIAN G
IPC: B29C67/00
Filed: 1991-03-01
Abstract: 一种固体仿形装置和一种采用有选择地一层一
层地光化辐照液态可光电加工混合物来制造具有多
重横截面的三维物体的方法。该装置包括装混合物
的容器，混合物具有自由表面，在离开平台的预定位
置降下和升起配置器使部分混合物移放到自由表面
上方，辅助装置与该混合物接触并移至平台上方形成
大致均匀的一层混合物。
Patent CN-1091604-A (CN)
Inventor: XIXIN ZHAO
IPC: A23L33/00
Filed: 1993-12-04
Abstract: “黑珍常春葆”营养液，属于人类生活必需中的保
健食品，它是以香菇、银耳和黑木耳为原料、配以蜂蜜
和防腐剂制成的棕红色透明的营养液，对降低血清胆
固醇有明显效果，同时对抗肿瘤有显著作用。
Patent CN-1177987-A (CN)
Inventor: TOMLINSON C E
IPC: C23C22/34
Filed: 1996-01-11
Abstract: 一种关于为金属表面提供具有耐蚀、亲水、低气味和抗生物特性的方法。这方法包括用氟化物,锆和质子酸的溶液对金属进行最初处理。然后再用处于碱性pH下的水溶性硅酸盐的溶液对上述金属进行处理。在每一步骤之后任选使用冲洗步骤,和优选烘箱干燥步骤作为本方法的最后步骤。
Patent CN-1209331-A (CN)
Inventor: WANG ENJIANG
IPC: A61K35/36
Filed: 1997-08-26
Abstract: 本发明属于一种来源于植物的材料配制的药品,是专治深静脉血栓形成的中药。它的组成为:苍术、黄柏、虎杖、银花、公英、丹参、川芎、三棱、香附、红花、甲珠、地龙、牛膝、泽泄。本发明的药物经临床和毒理实验证明,有效率高,服用安全,无副作用,对传统理论有所突破。
Patent CN-1223386-A (CN)
Title: 具有双轴取向着色薄层的照相元件
Inventor: GULA THADDEUS STEPHEN
IPC: G03C1/76
Filed: 1998-12-24
Abstract: 本发明涉及一种照相元件,它包括纸基底、至少一卤化银感光层、所述纸基质与所述卤化银层之间的聚合物片材层,在所述卤化银层的紧下方有着色聚合物薄层。
Patent CN-1264953-A (CN)
Title: 适应回流锡焊的小型马达
Inventor: TADAOTO YAMAGUCHI
IPC: H02K23/00
Filed: 1999-02-23
Abstract: 本发明提供的一种适应能回流锡焊的小型马达,其能用简单的构造解决磁铁热退磁问题。本发明的小型马达,在壳体内收容着磁铁,其特征在于,该磁铁用丙烯基类粘接片、耐热树脂等与构成壳体一部分的托架、轴等金属部件隔离开。
Patent CN-1288891-A (CN)
Title: 6－甲基－4羟基－2－吡喃酮的简便合成方法
Inventor: CHEN WANGYI
IPC: C07D309/38
Filed: 1999-09-21
Abstract: 本发明涉及一种简便的从丙二酸亚异丙基酯合成6－甲基－4－羟基－2－吡喃酮1的方法,将文献中的三步反应(见式1、2、3)，改进为在混合溶剂中一步进行(见式4)。
Patent CR-20110652-A (CR)
Title: Producto de proteína y procedimiento para preparar un producto de proteína inyectable
Inventor: KELLEHER STEPHEN D
IPC: A23L13/60
Filed: 2011-12-06
Abstract: Se retiene la humedad en alimentos cocinados o descongelados agregando al alimento una suspensión acuosa de proteína muscular animal obtenida de tejido muscular animal. La suspensión acuosa se obtiene mezclando tejido muscular animal triturado con una base de uso permitido en alimentos para formar una solución acuosa básica de proteína muscular animal.
Patent CR-20190201-A (CR)
Title: Naphthyridinone derivatives and their use in the treatment of arrhythmia
Inventor: BARBE GUILLAUME
IPC: C07D471/04
Filed: 2017-10-19
Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; (I) Wherein R1, R3-R6, X2 and X3 are as defined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.La presente invención proporciona un compuesto de fórmula (I) o una sal farmacéuticamente aceptable del mismo; (I) donde R1, R3¿R6, X2 y X3 son como se define en la presente descripción, un método para elaborar los compuestos de la invención, y sus usos terapéuticos. La presente invención además proporciona una combinación de agentes farmacológicamente activos y una composición farmacéutica
Patent CR-20190342-A (CR)
Title: Una fórmulacion agrícola que comprende diacil o diaril urea y una mezcla de nutrientes
Inventor: SHETH RITESH
IPC: C05G1/00
Filed: 2018-01-31
Abstract: Una fórmula agrícola sinérgica que incluye por lo menos una diacil o diaril urea, tal como una N,N¿-diformilurea, y por lo menos una mezcla de nutrientes, tal como una mezcla de micronutrientes y/o macronutrientes. Esta fórmula agrícola sinérgica confiere a las personas con capacitación en la técnica la posibilidad de regular importantes parámetros fenotípicos que dan lugar a una variedad de rasgos de importancia agronómica y hortícola que mejoran los parámetros de rinde de los cultivos más allá de lo que lo hacen sus componentes individuales.
Patent CR-20200294-A (CR)
Title: Aminoindanes amides having a high fungicidal activity and their phytosanitary compositions
Inventor: PELLACINI FRANCO
IPC: C07D231/14
Filed: 2011-12-19
Abstract: New aminoindanes amides are described, having general formula (I) the relative phytosanitary compositions and their use for the control of phytopathogenic fungi.
Patent CR-20210221-A (CR)
Title: Azithromycin and roxithromycin derivatives as senolytic drugs
Inventor: LISANTI MICHAEL P
IPC: A61P31/04
Filed: 2019-10-02
Abstract: This disclosure describes the use of azithromycin, roxithromycin, and telithromycin, including derivatives thereof, as senolytic drugs. BrdU was used to induce senescence in model human fibroblast cell lines. Also disclosed are methods for screening compounds for senolytic activity. The SRB assay was used to measure cell viability through protein content. Azithromycin roxithromycin, and telithromycin, clinically-approved pharmaceuticals, were found to be senolytic drugs. However, the closely-related parent compound, erythromycin, showed no senolytic activity. Azithromycin strongly induced both aerobic glycolysis and autophagy in human fibroblasts, but showed bi-phasic effects including on mitochondrial oxygen consumption rates with inhibitory activity at 50 μΜ and stimulatory activity at 100 μΜ. The xCELLigence real-time assay system showed that azithromycin preferentially targets senescent cells, removing approximately 97% (nearly a 25-fold reduction in senescent cells).
Patent EC-SP055635-A (EC)
Title: Agentes citotoxicos que contienen taxanos potentes novedosos y su uso terapeutico
Inventor: BALOGLU ERKAN
IPC: A61P33/00
Filed: 2005-02-28
Abstract: Incluidos dentro del alcance de la presente invención están taxanos potentes que contienen un grupo de enlace. Se incluye también un agente citotóxico que comprende uno o más taxanos enlazados a un agente de enlace celular. Una composición terapéutica para inducir muerte celular en poblaciones celulares seleccionadas que comprende: (A) una cantidad citotóxica de uno o más taxanos enlazados de manera covalente a un agente de enlace celular a través de un grupo de enlace, y (B) se incluye también un portador, diluyente o excipiente farmacéuticamente aceptable. Se incluye también un método para inducir la muerta celular en poblaciones celulares seleccionadas que comprende poner en contacto células de objetivo o tejido que contiene células de objetivo con una cantidad efectiva de un agente citotóxico que comprende uno o más taxanos vinculados a un agente de enlace celular.
Patent EC-SP982476-A (EC)
Title: Dispositivo para sacar un liquido de un deposito cerrado
Inventor: GESER JOHANNES
IPC: F15D1/00
Filed: 1998-04-14
Abstract: Para sacar un líquido de un depósito cerrado que en un aparato portátil tiene una posición espacial variable, hay que adoptar prevenciones para que pueda sacarse el líquido sin inconvenientes, y los más completamente posible. Un depósito cerrado se provee con un medio acumulador poroso de poros abiertos que está configurado como un cuerpo de una sola pieza. Preferentemente rellena tan sólo una parte del depósito, se encuentra al menos en la zona del extremo del racor de toma y toca al menos temporalmente el líquido. El medio acumulador sirve como acumulador previo para el líquido y como barrera contra las burbujas. Contiene permanentemente una cierta cantidad del líquido en la proximidad del extremo del racor de toma, incluso cuando su extremo está situado por encima del nivel del líquido en el depósito. El depósito provisto con el medio acumulador puede utilizarse como depósito de sustancia activa para un medicamento líquido en un nebulizador realizado como aparato manual con elque se produce un aerosol que se puede inhalar.
Patent FR-1453258-A (FR)
IPC: C22B5/04
Filed: 1965-01-14
Granted: 1966-09-16
Abstract: An exothermic composition for maintaining iron and steel liquid during and after casting comprises (percentages by weight):-ferrosilicon 5 to 30% (45 to 90% silicon); bauxite 5 to 25% (less than 5% silica); iron oxides and/or manganese oxides 40 to 70%; aluminium 5 to 20%; magnesium 0.2 to 3%.  Optional ingredients comprise:-up to 5% flux (e.g. CaF2, Na2F2, Na3AlF6), up to 5% burning-promoting material (e.g. alkali metal nitrates or chlorates), and up to 20% filler (e.g. marble powder, heavy spar, coke or charcoal).  Preferred grain sizes for the five main constituents are given, and two specific examples, which include hematite, potassium nitrate, and calcium fluoride, are described.
Patent GB-1051668-A (GB)
IPC: H01R24/84
Abstract: 1,051,668. Two-part couplings. WAGO-KLEMMENWERK G.m.b.H. June 18, 1963 [June 26, 1962; Oct. 9, 1962], No. 24191/63. Heading H2E. A connector comprises two identical coupling halves having projecting guide segments which interfit in only one position, and two coupling rings which cooperate to pull the two halves into engagement. In the embodiment of Fig. 9, the hollow coupling halves 31a, 31b, Fig. 10 (not shown), are each stepped to provide a guide 33 and a cavity 32, which are formed respectively with a diagonal recess 45a and corresponding web 45 and with a peripheral beading 46 and correspondingly-shaped groove 47 so that the abutting faces of the two halves 31a, 31b are sealed on engagement. Identical screw coupling rings 48 are shaped to fit over the coupling halves 31a, 31b, and each ring has two opposed projecting segments 50b, 50e obliquely grooved at 54a, 54b to provide lands 55a, 55b which engage in oblique grooves 52a, 52b formed in two opposed parts of the mating ring 48. The rings 48 may be locked together by interengaging bosses and recesses formed in grooves 52a, 52b and lands 55a, 55b, respectively (Figs. 16, 17, not shown), when the rings are made of elastically yielding material. The coupling rings 48 are retained on the halves 31a, 31b by rings 56 screwed or otherwise secured on to threaded portions 35 of the halves. Bifurcated spring contacts 66 are supported by a plate 63 which bears against a shoulder 37a in each coupling half, and are symmetrically arranged about a plate diameter as shown. A cable 58, Fig. 13 (not shown), is passed into a rear tapered sleeve 36 of each coupling half through a long anti-flexing sheath 57, the cable cores are connected to terminal lugs 70 projecting from the rear of plate 63, and the cable covering 61 is rolled back against an extension 59 of sheath 57. Sleeve 36 is then filled with a casting resin 62 which surrounds extension 59 to anchor the cable 58 and sheath 57 and may also extend as far as plate 63 to provide a watertight coupling. The sleeve 36 may be omitted and the threaded portion 35 of half 31a fixed into a mounting flange (Fig. 14, not shown). An alternative construction of connector (Figs. 1 to 3, not shown) is substantially similar to that described above, with minor differences in the shapes of the coupling halves, coupling rings (Figs. 4 to 7, not shown), and retaining rings. The latter parts may be made of moulded plastic or of metal in either construction. The screw coupling rings of the second connector may be locked together by a spring clip (Fig. 8, not shown), which almost surrounds the overlapping rings and has pins to snap into corresponding holes in the rings. Bayonet-type coupling rings (Figs. 18, 19, not shown) may be used instead of screw-rings. Another form of connector (Fig. 20, not shown) contains rubber sealing rings to provide a watertight coupling.
Patent GB-1054477-A (GB)
IPC: G11C11/04
Abstract: 1,054,477. Magnetic storage devices. TOKO KABUSHIKI KAISHA. July 7, 1965 [July 20, 1964], No. 28822/65. Heading H3B. An electrically-conductive wire coated with magnetic storage material which is used, for example, in a woven matrix store, has two or more concentric thin film coatings each having a different coercive force. The wire may be continuously coated or may have coatings at only those regions where row and column conductors coincide in a woven matrix. Optionally, insulating layers may be provided between the conductor and the inner film and between the two films. In operation, both thin films at a storage location are switched by the coincident application of a word write pulse and a digit pulse, whereas only the film with the lower coercive force is switched by a read pulse. Repeated read-out is therefore possible as the unswitched film restores the switched film to its initial state.