baber/WOPTO huggingface dataset:
Patent CA-2984961-A1 (CA)
Title: Sel de sodium d'inhibiteur de transporteur d'acide urique et sa forme cristalline
Inventor: WU GUAILI
IPC: C07D215/36
Filed: 2016-05-26
Abstract: La présente invention concerne un sel de sodium d'un inhibiteur de transporteur d'acide urique et sa forme cristalline. En particulier, la présente invention concerne le sel de sodium d'un inhibiteur de transporteur d'acide urique (URAT1), et le cristal de type I associé et leur procédé de préparation. La présente invention concerne le 1-((6-bromo-quinoléine-4-yl)thio)cyclobutyl-formiate de sodium (le composé de formule (I)), et le cristal de type I associé et leur procédé de préparation. Le cristal de type I du composé de formule (I) obtenu dans la présente invention présente de bonnes propriétés de stabilité de la forme cristalline et de stabilité chimique, et le solvant de cristallisation utilisé présente une faible toxicité et entraîne peu de résidus, et peut être mieux utilisé dans un traitement clinique.
Patent CA-2985860-A1 (CA)
Inventor: ZHANG KEFEI
IPC: A61N5/067
Filed: 2016-03-01
Abstract: An imaging dot matrix laser treatment instrument, comprising: a locating insertion tube (1) comprising a hollow tube open at two ends, configured to locate a treatment region and define a laser beam path; a beam combiner lens component (2) comprising a hollow tube having openings at two ends thereof and a lateral opening arranged at a side thereof, wherein one end of the beam combiner lens component is connected to one end of the locating insertion tube (1); a camera head (3) connected to the beam combiner lens component (2) via the lateral opening to form an image of the treatment region; a laser scanning component connected to another end of the beam combiner lens component (2) to generate, according to the image of the treatment region, a laser beam scanning the treatment region; and a control system (4) connected to the laser scanning component and the camera head (3), respectively. The imaging dot matrix laser treatment instrument is simple in operation, reducing operation time and surgeon workload, and an increasing treatment efficiency and success rate.
Patent CA-2987981-A1 (CA)
Inventor: SALTERS BART ANDRE
IPC: B63B59/04
Filed: 2016-05-11
Abstract: The invention provides an object (10) that during use is at least partly submerged in water, the object (10) further comprising an anti-biofouling system (200) comprising an UV emitting element (210), wherein the UV emitting element (210) is configured to irradiate with UV radiation (221) during an irradiation stage one or more of (i) a part (111) of an external surface (11) of said object (10) and (ii) water adjacent to said part (111) of said external surface (11), wherein the light source (220) is at least controllable between a first UV radiation level and a second UV radiation level, wherein the first UV radiation level is larger than the second UV radiation level, wherein the object (10) is selected from the group consisting of a vessel (1) and an infrastructural object (15), wherein the object (10) further comprises a control system (300) configured to control said UV radiation (221) as function of input information comprising information of one or more of (i) a location of the object (10), (ii) movement of the object (10), (iii) a distance (d) of the object (10) to a second object (20), and (iv) a position of the part (111) of the external surface (11) relative to the water.
Patent CA-2988536-A1 (CA)
Title: Composition et procede permettant d'induire une reponse anti-inflammatoire
Inventor: ASHLEY ROBERT A
IPC: A61M37/00
Filed: 2016-06-14
Abstract: La présente invention concerne d'une façon générale la détoxification métabolique, et plus particulièrement une composition et un procédé pour induire une réponse anti-inflammatoire dans une cellule, ainsi que le traitement d'une maladie chez un sujet.
Patent CA-2992159-A1 (CA)
Inventor: FERGUSON EWEN JAMES
IPC: C10L1/04
Filed: 2016-07-14
Abstract: Porous, extruded titania-based materials further comprising one or more acids and/or prepared using one or more acids, Fischer-tropsch catalysts comprising them, uses of the foregoing, processes for making and using the same and products obtained from such processes.
Patent CA-2992247-A1 (CA)
Inventor: CULPEPPER PATRICK M
IPC: E04F13/18
Filed: 2018-01-18
Abstract: A composite siding panel mountable on an exterior wall of a building includes a backing member and a siding member attached to the backing member, wherein the first side edge of the siding member overhangs the first side edge of the backing member, and the second side edge of the siding member is aligned with or positioned contiguously with the second side edge of the backing member. An adhesive coating joins the front face of the backing member to the rear face of the siding member. The adhesive coating runs substantially from the first side edge of the backing member to the second side edge thereof. The backing member can be composed of closed-cell expanded foam or wire- fabricated foam, and the siding member can be formed from vinyl, polypropylene, aluminum, steel, fiberglass, engineered wood, or fiber cement. A siding assembly including a plurality of composite siding panels adjacently mountable on an exterior wall of a building is also disclosed.
Patent CA-2993991-A1 (CA)
Inventor: LEE JOHN JONG HOON
IPC: H01P7/06
Filed: 2016-08-30
Abstract: A flip-chip employing an integrated cavity filter is disclosed comprising an integrated circuit (IC) chip comprising a semiconductor die and a plurality of conductive bumps. The plurality of conductive bumps is interconnected to at least one metal layer of the semiconductor die to provide a conductive "fence" that defines an interior resonator cavity for providing an integrated cavity filter in the flip-chip. The interior resonator cavity is configured to receive an input RF signal from an input transmission line through an input signal transmission aperture provided in an internal layer in the semiconductor die. The interior resonator cavity resonates the input RF signal to generate the output RF signal comprising a filtered RF signal of the input RF signal, and couples the output RF signal on an output signal transmission line in the flip-chip through an output transmission aperture provided in the aperture layer.
Patent CA-2994423-A1 (CA)
Inventor: LEVINSON MICHAEL DANIEL
IPC: G06Q10/04
Filed: 2016-08-16
Abstract: An advertisement system measures an ad lift metric for advertisement campaigns, which indicates the increase in conversions that can be attributed to the advertisement campaign. As impression opportunities become available for users for the ad in the lift study, the advertisement system determines whether the user is in a test group or a control group. To limit bias in the lift study, rather than holding out ads from being provided to users after the ad has been selected for the user and right before the impression, the system holds out the ads at a higher level in the ad selection process. In this manner, not all test group users receive the advertisement. The system computes the lift metric as e.g., the incremental lift (difference between conversion rates in the test and control groups), and this is divided by conversion rate of an exposed target group minus the incremental lift.
Patent CA-2994687-A1 (CA)
Inventor: GALVIN GABRIEL M
IPC: C07J41/00
Filed: 2016-08-05
Abstract: The present application relates to a method of preparing compounds of Formula (A) or a pharmaceutically acceptable salt, solvate, or amino acid conjugate thereof.
Patent CA-2997308-A1 (CA)
Title: Method for a combined cell digestion and extraction of oil-containing seeds
Inventor: BORNER GUNTER
IPC: C11B1/04
Filed: 2016-09-03
Abstract: The invention relates to a method of combined cell digestion and extraction of oil-containing seeds having an oil content of > 30% by mass, wherein production of a slurry from the oilseeds and ethanol is followed by a combination of cell digestion with a subsequent ethanolic extraction, wherein the smaller portion of the oil present in the seed cells of the oilseed and the alcohol-soluble constituents present therein are transferred to the ethanol in accordance with the dissolution capacity of the ethanol for the oil and the alcohol-soluble constituents, and another, greater portion of the oil is displaced from the seed cells of the oilseed by the ethanol, forming a free oil phase in the ethanol. The free oil phase is removed and, according to the invention, has semi-raffinate quality. The complexity of refining that has been reduced thereby is a result and an advantage of the method of the invention.
Patent CA-2998603-A1 (CA)
Inventor: PASSINI MARCO A
IPC: A61K38/48
Filed: 2006-05-02
Abstract: La divulgation porte sur des méthodes et des compositions de traitement des troubles affectant le système nerveux central (SNC). Ces troubles comprennent les troubles métaboliques comme les troubles de stockage lysosomal qui affectent le système nerveux central, p. ex., la maladie de Niemann-Pick A. Ils comprennent également les troubles comme la maladie dAlzheimer. Les méthodes divulguées comprennent la mise en contact dune extrémité axonale dun neurone avec une composition ayant une teneur élevée en dépendovirus (AAV) transportant un transgène thérapeutique de sorte que le vecteur AAV est transporté par axone dune manière rétrograde et le produit transgénique est exprimé de manière distale par rapport au site dadministration.
Patent CA-3000062-A1 (CA)
Inventor: ROSELLO GARGALLO ALEX
IPC: B28D1/22
Filed: 2016-07-19
Abstract: The invention relates to a cutting and separating device applicable to manual ceramic cutters, comprising: a carriage (1); a collapsible handle (3) with a cutting tool (4); a toothed part (5) comprising a separator (6) for separating ceramic parts; springs (10, 13) for holding the toothed part (5) in a inoperative position as well as a toothed actuator (12) in an engaged position with the toothed part (5); and a manual trigger element (14, 15) for disengaging the toothed actuator (12). The rotation of the handle (3) past a pre-determined angle causes the engagement of the toothed actuator (12) in the toothed part (5); the descending rotation causes the toothed actuator (12) to rotate the toothed part (5) until an operative position of the separator (6) is reached; and the actuation of the trigger element (14, 15) causes the release of the toothed part (5) and the return thereof to the inoperative position.
Patent CA-3001026-A1 (CA)
Inventor: ZANKE BRENT
IPC: G16B20/20
Filed: 2018-04-11
Abstract: Human chronic diseases thought to have an immunological etiology are associated with particular changes in the gut microbiota. While bacterial profiles may be a consequence of the disease state, animal fecal transfer experiments suggest that disease predisposition can be transferred along with the microbiota. Diet can influence bacterial genome composition and may modulate disease predisposition via this mechanism. Disclosed are specific genotypes derived from human Complement Factor H (CFH) and ARMS2 gene SNPs that are associated with characteristic microbiome composition in humans. These polymorphisms are associated with diseases of human aging such as Alzheimer disease and age-related macular degeneration.  Specific secondary prophylactic measures that affect the course of these diseases alter the gut microbiota and ameliorate genotype-specific, disease-associated changes.  Personalized therapy for individuals with Alzheimer disease and age-related macular degeneration are selected based on observed interactions of the microbiota and CFH and ARMS2 genotypes.
Patent CA-3001358-A1 (CA)
Inventor: ILIAS SAMIA
IPC: C10G3/00
Filed: 2016-10-25
Abstract: Processes for forming refined hydrocarbons are disclosed. Exemplary processes include providing a first mixture comprising = 10 wt% of at least one oxygenate; contacting at least a portion of the first mixture with a methanol conversion catalyst under suitable conditions including a first pressure, P1, to yield an intermediate composition including olefins having at least two carbon atoms; introducing at least a portion of the intermediate composition to an oligomerization catalyst under suitable conditions including a second pressure, P2, to yield an effluent mixture comprising gasoline boiling range components and distillate boiling range components; and recovering at least a portion of the gasoline boiling range components and distillate boiling range components. The first and second pressure can be relatively similar. Apparatus and systems for carrying out the disclosed processes are also described.
Patent CA-3002747-A1 (CA)
Title: Immunoassay to detect cleaved high molecular weight kininogen
Inventor: SEXTON DANIEL J
IPC: G01N33/86
Filed: 2016-10-19
Abstract: The present disclosure provides immunoassay methods of detecting a cleaved high molecular weight kininogen (HMWK) with high sensitivity and specificity and isolated antibodies that specifically bind cleaved HMWK.
Patent CA-3012176-A1 (CA)
Title: Photo-cleavable primer compositions and methods of use
Inventor: AHN BYUNG JUN
IPC: C09D7/63
Filed: 2017-01-27
Abstract: In one embodiment, the present application discloses a photo-cleavable surface binding compound of the Formula I and Formula II: wherein the variables EG, EG1, SP1, SP2, SP3, Ar and BG are as defined herein. In another embodiment, the application discloses a method for forming a coating on a surface of a substrate using the surface binding compound.
Patent CA-3013182-A1 (CA)
Inventor: WRIGHT CRAIG STEVEN
IPC: G06Q20/38
Filed: 2017-02-14
Abstract: A method of creating, redeeming and transferring tokens associated with tokens on a peer-to-peer distributed ledger. The method includes including metadata associated with the token in a redeem script, wherein the redeem script is associated with a transaction of cryptocurrency on the peer-to-peer distributed ledger. One aspect of the invention provides a method of issuing and/or transferring a token, comprising the steps of generating a blockchain transaction (Tx) having an output (Tx O) related to a quantity of cryptocurrency such as Bitcoin, and a hash of a redeem script. The redeem script comprises metadata which in turn comprises a token. The token is a representation of, or a reference to, a tokenised entity. The redeem script also comprises at least one (preferably two or more) public cryptographic keys. The metadata is provided in the redeem script at a location which is designated in the underlying blockchain protocol as a location for a cryptographic key.
Patent CA-3013314-A1 (CA)
Title: Top feeding wicking apparatus and system
Inventor: MARSHALL AARON
IPC: A01G27/06
Filed: 2017-01-27
Abstract: A top feeding wicking apparatus and system for dispersing liquid through plant growing medium is disclosed. The apparatus includes a geometrically shaped container having a bottom, an inner wall, and an outer wall forming a channel therearound for receiving liquid therethrough. Container has a center opening for receiving a plant and container bottom is configured with at least one hole for receiving liquid therethrough. A geometrically shaped lid having a top, an inner wall, and an outer wall forming a channel therearound from an underside of lid is configured to be adjoined to container. A geometrically shaped base layer and wicking layer each having an inner wall and an outer wall and a center opening for receiving plant with a longitudinal opening extending therefrom to outer wall to allow placement of base and wicking layers on plant or to allow removal of base and wicking layers from plant. Container with lid is configured to set atop base layer and wicking layer such that liquid is dispersed through plant growing medium.
Patent CA-3017599-A1 (CA)
Inventor: BECK CHASEN SCOTT
IPC: E05B47/00
Filed: 2017-03-29
Abstract: A locking device with a bolt movable between a locked position and an unlocked position. The locking device includes an electronic controller for selectively controlling movement of the bolt between the locked and unlocked position. At least two input devices are provided, such as a keypad, a biometric input, etc., which communicate an authentication code to the controller. The controller controls movement of the bolt based on a valid authentication code received from any of the at least two input devices.
Patent CA-3017835-A1 (CA)
Title: Appareil d'analyse, methode d'analyse et support de stockage
Inventor: HIRAKAWA YASUFUMI
IPC: G08B25/00
Filed: 2017-02-13
Abstract: Afin de résoudre les problèmes de l'état de la technique, la présente invention concerne un dispositif d'analyse (10) comprenant : une unité d'extraction de personnes (11) qui analyse des données d'image en mouvement et extrait des personnes ; une unité de calcul de temps (12) qui calcule, pour chaque personne extraite, une durée d'apparition, qui est la durée pendant laquelle la personne extraite était présente dans une zone prédéterminée, et un temps de réapparition, qui est le temps qu'il a fallu à la personne extraite pour réapparaître dans la zone prédéterminée après la disparition de la zone prédéterminée ; et une unité d'estimation (13) qui estime des caractéristiques de chaque personne extraite sur la base de la durée d'apparition et du temps de réapparition de la personne.
Patent CA-3018624-A1 (CA)
Inventor: ARNIN URI
IPC: A61F2/44
Filed: 2016-03-30
Abstract: A spinal cage (10) includes a first support plate (12) pivotally connected to a second support plate (14) by a hinge (16), and a plate mover (18) actuated by an actuator (22) and located between the first and second support plates (12, 14). The plate mover (18) is arranged to slide against an inclined surface (20) on the first support plate (12). A hinge (16) is journaled in an elongate aperture (24) formed in a hinge housing (26) protruding from first support plate (12), the hinge (16) being free to translate and rotate in the elongate aperture (24).
Patent CA-3018664-A1 (CA)
Inventor: LEPRETRE GILLES
IPC: F01D25/24
Filed: 2017-03-20
Abstract: A turbine ring assembly comprises ring segments (10) made of a ceramic matrix composite material that form a turbine ring (1) and a ring support structure (3) comprising a first and a second annular flange (32, 36), each ring segment having a first and a second tab (14, 16) that are held between the two annular flanges (32, 36) of the ring support structure (3). First and second holding elements (40, 41) that are secured to the first annular flange (32) are received in first and second openings (142, 143) of the first tab (14), while first and second holding elements that are secured to the second annular flange (36) are received in first and second openings of the second tab (16). When cold, radial play exists between the openings and that part of the holding elements that is present in said openings. The first and second annular flanges (32, 34) comprise, on their face opposite the first and second tabs (14, 16), a plurality of bearing portions (34, 38) that are distributed circumferentially around the flanges, the ends (141, 161) of the first and second tabs (14, 16) of each ring segment abutting radially against two bearing portions (34, 36) when cold.
Patent CA-3018923-A1 (CA)
Inventor: COULTER TOM
IPC: A61K47/40
Filed: 2017-03-29
Abstract: The present invention provides a method for producing a cyclodextrin-panobinostat adduct, comprising: a) providing a first aqueous solution comprising a buffering agent, the solution having a pH in the range 2.0 to 4.0; b) dissolving panobinostat in said first aqueous solution to provide a second aqueous solution; and c) mixing said second aqueous solution comprising panobinostat with a third aqueous solution comprising a cyclodextrin to form a fourth aqueous solution comprising a cyclodextrin-panobinostat adduct. Also provided is an artificial cerebrospinal fluid (CSF) solution comprising the cyclodextrin-panobinostat adduct and medical uses of the cyclodextrin-panobinostat adduct, including in the treatment of brain tumours.
Patent CA-3019031-A1 (CA)
Title: A one-piece shingle repair patch
Inventor: MATHIESON THOMAS R
IPC: E04D1/12
Filed: 2018-09-27
Abstract: A shingle patch for repairing damaged shingles or overlaying exposed nails on a roof structure including a base member with and without a notched portion on one end for sliding under an existing shingle located above the damaged shingle or the shingle with exposed nails, a sealant covering at least a portion of the notched portion and the bottom surface of the base member for attaching the base member to the damaged shingle or to another shingle, and color granules associated with at least a portion of the top surface of the base member. The shingle patch can likewise include a fold for mating with a peak on a roof for overlaying exposed nails associated with a last ridge cap shingle or it can be used flat to cover exposed nails at roof/wall intersections and the like. The notched portion can also be formed solely from the sealant member.
Patent CA-3019087-A1 (CA)
Title: Sol pour application par pulverisation, corps moule en resine de chlorure de vinyle avec couche appliquee par pulverisation ainsi que procede de fabrication de celui-ci, et stratifie
Inventor: IWABUCHI SATOSHI
IPC: C08J7/04
Filed: 2017-03-23
Abstract: L'invention fournit un sol pour application par pulvérisation possédant une fluidité adéquate, et doté d'une excellente stabilité à la chaleur. Le sol pour application par pulvérisation de l'invention qui est destiné à former une couche appliquée par pulvérisation pour un matériau intérieur d'automobile, contient des microparticules à base de chlorure de vinyle, un plastifiant et un solvant, et présente une viscosité supérieure ou égale à 500mPa·s et inférieure ou égale à 50000mPa·s.
Patent CA-3020941-A1 (CA)
Title: Low profile feeder and use therefor
Inventor: SUBRAMANIAM NARENDRAN
IPC: B60P1/56
Filed: 2018-10-15
Abstract: A feeder such as low profile feeder for defining a tray bed of a truck tray having an outermost rear edge, and an outermost front edge for discharge of cargo contained in the tray, the tray comprising a hopper having a rear wall defining the outermost rear edge of the tray, and side walls extending from the rear wall towards the outermost front edge of the tray, the side walls of the hopper having lower edges for attachment of the feeder, and the feeder comprising an endless belt structure for defining a load carrying surface and a platform adapted to receive the endless belt structure to permit cyclical movement of the endless belt structure around the platform for conveying material out of the tray through the outermost front edge of the tray.
Patent CA-3024476-A1 (CA)
Inventor: KUIPERS ANNEMARIE
IPC: C07K16/12
Filed: 2017-05-17
Abstract: La présente invention concerne des molécules d'anticorps qui se lient à l'acide téichoïque de paroi (WTA) ou à des polysaccharides capsulaires (CP) tels que les polysaccharides capsulaires de type 5 (CP5). L'invention concerne en particulier des molécules d'anticorps de l'isotype IgG ayant une mutation dans le domaine Fc qui améliore l'agrégation de molécules d'IgG après liaison à la cible. L'invention concerne en outre des compositions pharmaceutiques contenant ces molécules et le traitement de maladies infectieuses au moyen de ces compositions