baber/WOPTO huggingface dataset:
Patent CA-3079260-A1 (CA)
Title: Composes heterocycliques a substitution amine utilises comme inhibiteurs de l'ehmt2 et derives de ces derniers
Inventor: CAMPBELL JOHN EMMERSON
IPC: C07D257/08
Filed: 2018-10-17
Abstract: L'invention concerne des composés hétérocycliques à substitution amine et des dérivés de ces derniers. La présente invention concerne également des compositions pharmaceutiques contenant ces composés et des méthodes de traitement d'une maladie (par exemple, le cancer) par administration d'un composé hétérocyclique à substitution amine selon cette invention, ou d'une composition pharmaceutique de celui-ci, à des sujets ayant besoin d'un tel traitement. La présente invention concerne également l'utilisation desdits composés pour la recherche ou à d'autres fins non thérapeutiques.
Patent CA-3081202-A1 (CA)
Inventor: ZHU KANGYING
IPC: C22C38/14
Filed: 2018-11-21
Abstract: The invention deals with a cold-rolled and heat-treated steel sheet, made of a steel having a composition comprising, by weight percent:: C : 0.03 - 0.25 % Mn : 3.5 - 8 % Si : 0.5 - 2.0 % Ai : 0,03 - 2.0 % Ti < 0.080 % Nb < 0.080 % V < 0.2 % V + Ti + Nb > 0.01% S < 0.010 % P < 0.020 % N < 0.008 % and comprising optionally one or more of the following elements, in weight percentage: Mo : 0.1 - 0.5 % Cr : 0.01 - 1 % B : 0.0005 - 0.004 % the remainder of the composition being iron and unavoidable impurities resulting from the smelting, said cold-rolled steel sheet having a microstructure consisting of, in surface fraction: - between 10% and 30% of retained austenite, said retained austenite being present as films having an aspect ratio of at least 3 and as Martensite Austenite islands, less than 8% of such Martensite A islands having a size above 0.5 pm, - at most 1 % of fresh martensite - at most 50% of tempered martensite and - recovered martensite containing precipitates of at least one element chosen among niobium, titanium and vanadium. it also deals with a manufacturing method thereof.
Patent CA-3081939-A1 (CA)
Title: Systeme de reponse vocale interactif synchronise et interface utilisateur graphique pour service d`assistance routiere automatise
Inventor: TURNBULL PAUL R
IPC: G10L15/22
Filed: 2020-05-29
Abstract: Il est décrit des systèmes et des méthodes visant à fournir un service dassistance routière par le biais dun système de réponse vocale interactif (SRV) synchronisé et dune interface utilisateur graphique (IUG). Une méthode peut consister à recevoir, lors dun appel téléphonique entrant provenant dun dispositif dutilisateur de véhicule, une demande de service dassistance routière pour un véhicule en panne dun utilisateur de véhicule; envoyer un texte à un numéro de téléphone du dispositif dutilisateur de véhicule, le texte comprenant un lien vers une application mobile pour les demandes de service dassistance routière; recevoir, du dispositif dutilisateur de véhicule et par lintermédiaire de lapplication mobile, des renseignements liés à la demande de service dassistance routière; déterminer, en fonction dun capteur de localisation de lappareil de lutilisateur du véhicule, la localisation du véhicule en panne; mettre en relation un fournisseur de services dassistance routière avec le véhicule en panne en fonction de la demande de services dassistance routière; et permettre à lutilisateur du véhicule de suivre létat de service du fournisseur de services dassistance routière par lintermédiaire de lapplication mobile.
Patent CA-3082462-A1 (CA)
Title: Dispositif de survie en avalanche comprenant un appareil respiratoire
Inventor: BERGE Tor
IPC: A62B7/00
Filed: 2018-11-13
Abstract: La présente invention concerne un dispositif, un procédé et un système pour améliorer la qualité de l'air respirable de l'environnement dans la région d'une partie spécifique d'un corps, telle qu'une qualité d'air respirable autour de la région de la bouche et du nez d'une personne étant enfouie dans une avalanche. Le dispositif comprend au moins une entrée (4, 83, 120), au moins une pompe (3, 85), au moins une ressource de puissance (5, 121), un dispositif de commande (6) et au moins une sortie (1, 80), l'au moins une entrée (4, 83, 120) est raccordée à une entrée de pompe (31, 88) de la pompe (3, 85), et l'au moins une sortie (1, 80) est raccordée à une sortie de pompe (32, 122) de la pompe (3, 80), l'entrée (4, 83, 120) étant construite pour servir de chambre (4, 4', 7', 81, 82, 120'), une première extrémité de la chambre étant raccordée à l'entrée de pompe (31, 88) et une deuxième extrémité de la chambre étant une ouverture (4', 83, 123) vers l'extérieur du dispositif, la pompe (3, 85), lorsqu'elle est activée, fournissant un vide dans la chambre et aspirant l'air depuis l'environnement dans la pompe à travers la deuxième extrémité de la chambre et la chambre, et pompant l'air de la sortie de pompe (32, 122) vers la sortie (1, 80).
Patent CA-3084021-A1 (CA)
Inventor: YANG XINYING
IPC: G10G1/00
Filed: 2019-05-09
Abstract: One or more implementations of the present specification provide a blockchain-based music originality analysis method and apparatus. In an implementation, a music file published on a blockchain network comprising a music library node and a music analyzer node is obtained by the music library node. An originality analysis is performed by the music library node on the music file based on a local music library to obtain a first originality and analysis digest that is used to indicate an originality and analysis result. The music library node publishes the first originality and analysis digest to the blockchain network to record and authenticate the originality and analysis result. The music analyzer node obtains and summarizes the first originality and analysis digest to obtain a second originality and analysis digest and performs processing of a service related to originality of the music file based on the second originality and analysis digest.
Patent CA-3085326-A1 (CA)
Title: Dynamic dosing systems for phototherapy and associated devices, systems, and methods
Inventor: MOFFAT WILLIAM ALEXANDER
IPC: A61N5/06
Filed: 2018-12-13
Abstract: Dynamic dosing systems for phototherapy and associated devices, systems, and methods are disclosed herein. In some embodiments, a dynamic dosing phototherapy system can include a self-service phototherapy kiosk ("SPK") configured to emit UV radiation, a user interface communicatively coupled to the SPK, and a dynamic dosing system communicatively coupled to the user interface and the SPK. The dynamic dosing system can determine initial, user-specific parameters specific to define a first individual phototherapy protocol, and then determine adjustments to the initial parameters and the first individual phototherapy protocol based on user inputs related to erythema response to a previous phototherapy treatment session. The SPK can deliver UV radiation to a user in accordance with the first individual phototherapy protocol and/or an adjusted, second phototherapy protocol that takes into account the user's erythema response.
Patent CA-3086056-A1 (CA)
Inventor: SAHIN FIKRETTIN
IPC: A61P35/00
Filed: 2018-12-17
Abstract: The present invention relates to production of a drug which is specific for SH- SY5Y neuroblastoma cancer by loading CAPE to microvesicles that the specialized skin cell leaves into the nutrient solution. The objective of the present invention is to provide a cell-specific targeted vesicle development by loading CAPE to the microvesicles obtained as a result of the culturing and subsequent specialization (differentiation) of the tissue cells; and to use CAPE at lower concentrations compared to the state of the art applications to minimize its toxicity to both the cells other than the targeted cells and the body.
Patent CA-3091846-A1 (CA)
Title: Wheat variety 6pymg52b
Inventor: LASKAR WILLIAM JOSEPH
IPC: A01H5/00
Filed: 2020-09-02
Abstract: A wheat variety designated 6PYMG52B, the plants and seeds of wheat variety 6PYMG52B, methods for producing a wheat plant produced by crossing the variety 6PYMG52B with another wheat plant, and hybrid wheat seeds and plants produced by crossing the variety 6PYMG52B with another wheat line or plant, and the creation of variants by backcrossing, mutagenesis or transformation of variety 6PYMG52B are disclosed. Methods for producing other wheat varieties or breeding lines derived from wheat variety 6PYMG52B and to wheat varieties or breeding lines produced by those methods are also provided.
Patent CA-3092591-A1 (CA)
Inventor: BIERMAN STEVEN F
IPC: A61M29/00
Filed: 2019-02-26
Abstract: The device includes a dilator with a hub (38) and an elongated body (36). A locking mechanism (30) is configured to limit a distance a guidewire (28) can be advanced out of a distal end of the dilator. The guidewire has a guidewire stop (92B) being receivable through the elongated dilator body (36). The guidewire lock (30) having at least one member being moveable between an engaged state and a non-engaged state and being biased toward the engaged state in which the guidewire lock interacts with the guidewire. The locking mechanism and the dilator are configured to permit removal of the locking mechanism (30) from the dilator by moving the guidewire (28) axially in a proximal direction relative to the dilator with the guidewire stop abutting at least part of the portion of the locking mechanism that an opening extends through.
Patent CA-3093191-A1 (CA)
Title: Apparatus for trapping harmful flying insects and method for counting trapped insects
Inventor: BELLAGAMBI PIERRE
IPC: A01M1/06
Filed: 2019-03-05
Abstract: The invention relates to an apparatus for trapping harmful flying insects comprising: a device (1) for spraying a gaseous attractive cocktail the composition of which is suitable for attracting the insects, a suction device (2) having a suction orifice (220) for a stream of air containing the insects attracted by the sprayed attractive cocktail, a trap arranged with the suction device (2), and a body (4) enclosing a source of gas, which gas is a constituent of the gaseous attractive cocktail, characterised in that the optical insect counter comprises a series of parallel deflectors (30) that are installed across the suction orifice (220), a light gate composed of a light emitter (31) and a light receiver (32) being installed in each interval between said deflectors.
Patent CA-3093687-A1 (CA)
Inventor: ROUSSEAU DIANE
IPC: A61B90/17
Filed: 2020-09-21
Abstract: breast positioning device for breast cancer radiation therapy includes i) a body portion made of a stretchable synthetic fabric and having a generally tubular shape configured for tight fitting on a person torso, ii) a bra cup on a first portion on the body portion, defining a first lateral side thereof, and iii) a flat portion on a second portion on the body portion, defining a second lateral side, the second portion being positioned laterally symmetrical to the first portion on the body portion. The bra cup is thermoformed in the stretchable synthetic fabric to have a greater transparency than surroundings thereof rendering a first breast therein visible while immobilizing the first breast therein in a predetermined position. When the breast positioning device is worn by a person during the breast cancer radiation therapy, the bra cup immobilizes the first breast therein in the predetermined position which is both visible and suitable for treatment while forcing a second breast in a flattened position away from the first lateral side.
Patent CA-3100685-A1 (CA)
Title: Nouveaux procedes de preparation d'un derive de diaminopyrimidine ou d'un sel d'addition d'acide de celui-ci
Inventor: KHOO JA-HEOUK
IPC: C07D403/04
Filed: 2019-05-16
Abstract: La présente invention concerne un nouveau procédé de préparation d'un dérivé de diaminopyrimidine ou d'un sel d'addition d'acide de celui-ci ayant une activité en tant qu'agoniste du récepteur 5-HT4. La présente invention concerne également de nouvelles formes cristallines d'un chlorhydrate du dérivé de diaminopyrimidine et des procédés de préparation associés.
Patent CA-3102200-A1 (CA)
Inventor: FIORITTI PAUL GREGORY
IPC: B65D35/24
Filed: 2020-12-11
Abstract: The current device is a durable and reusable plastic clip made specifically for retaining toothpaste towards the cap end of toothpaste tubes. The device is made up of a thin and flat piece of rectangular shape plastic with 2 parallel elongated holes, cut to allow insertion of the flat tapered ends of toothpaste tubes. The end of the toothpaste tube is inserted upward through the first hole then downward through the second hole. This design allows the user to adjust tension by pushing and pulling the toothpaste tube through the holes in the clip. Once the end of the toothpaste tube is weaved through the plastic retainer clip it will automatically stay firmly in place. Since the average person brushes their teeth at least two times a day or more this device will be very beneficial to users. This device will save countless amounts of time constantly squeezing toothpaste towards the cap end of the tube. Plastic is the easiest and cheapest material from which the toothpaste retainer clip can be made and has functioned extremely well in tests.  Although other materials such as brass or steel could be used, it would increase the cost of the device. The device may also be used for other materials which are packaged in flexible tubes such as silicone or contact cement if desired.
Patent CA-3103195-A1 (CA)
Title: Hydrothermal treatment device, biomass fuel manufacturing plant, hydrothermal treatment method, and biomass fuel manufacturing method
Inventor: SHIMBO YOICHI
IPC: C02F11/12
Filed: 2019-05-30
Abstract: The purpose of the present invention is to reduce the water content of treated matter after a hydrothermal treatment, and reduce the energy required when separating and removing water from the treated matter after the hydrothermal treatment. A hydrothermal treatment device (3) for heating and thereby performing hydrothermal treatment on high-water-content biomass, wherein the hydrothermal treatment device (3) is provided with: a treatment container (21) for storing a sludge; a sludge feed unit (22) for feeding the sludge into the treatment container (21) so as to form a space (S) in the vertically upper section of the treatment container (21); a stirrer (23) provided in the treatment container (21), the stirrer (23) stirring stored matter so that a counter flow is produced in the vertical direction; and heat transfer tubes (24) disposed in the treatment container (21) in the horizontal direction, the heat transfer tubes (24) heating the sludge by means of heat of water vapor flowing therein.
Patent CA-3104428-A1 (CA)
Title: A temperature regulating system
Inventor: GUERITEE JULIEN
IPC: A61F7/00
Filed: 2018-07-05
Abstract: The invention relates to a temperature regulation system for regulating the temperature of a portion of a body, in particular of a user's body. The system comprises at least one temperature sensor 1004a, 1004b, 1004c adapted to generate a temperature measurement that relates to a temperature of a given portion of a body, at least one temperature adjustment element 1006a, 1006b, 1006c adapted to provide heat and/or cold to a given portion of the body, arranged on or in the flexible support, a memory unit 1016, 1024 adapted to store at least one threshold temperature related value, a controlling unit 1022, 1024, 1032, 1034 in communication with the temperature sensor, with the memory unit 1016, 1024 and with the temperature adjustment element. The controlling unit is configured to receive the instant temperature of a given portion of the body from the temperature sensor, perform a comparison between at least one instant temperature related value and a triggering temperature related value, activate the temperature adjustment element to provide heat or cold to a given portion of the body depending on the result of said comparison. The memory unit is further adapted to store at least one user profile information related to a user profile parameter, and the controlling unit is further configured to determine the triggering temperature related value based on said threshold temperature related value, said user profile information and at least one user activity information related to a user instant activity parameter.
Patent CA-3108648-A1 (CA)
Inventor: GELLERT PAUL
IPC: A61K9/19
Filed: 2019-08-15
Abstract: Disclosed are pharmaceutical compositions comprising a lyophilized compound of formula (I): (I) or a pharmaceutically acceptable salt thereof, and methods of using the same for treating cancer.
Patent CA-3112031-A1 (CA)
Inventor: LEO CHIARA SILVANA
IPC: A61K47/06
Filed: 2019-10-11
Abstract: The invention provides ophthalmic compositions comprising 0.1 % (w/ v) cyclosporine dissolved in l-(perfluorobutyl)pentane for use in the topical treatment of dry eye disease. The invention further provides kits comprising such compositions for the same use.
Patent CA-3114411-A1 (CA)
Inventor: PRADHAN MANOJ
IPC: G01N27/22
Filed: 2019-10-17
Abstract: An electrical device comprising: voltage carrying components, a solid insulation system (8) configured to electrically insulate the voltage carrying components, and a moisture sensor (2) configured to detect moisture in the solid insulation system (8), wherein the moisture sensor (2) comprises: a capacitor (9) having: a first electrode (3), a second electrode (5), and a dielectric material (7) arranged between the first electrode (3) and the second electrode (5), wherein the solid insulation system (8) forms the dielectric material (7), the capacitance of the capacitor (9) providing an indication of a moisture level in the dielectric material (7).
Patent CA-3115381-A1 (CA)
Title: Helmet provided with a ring for connecting the helmet to an anti-theft system
Inventor: SADAOUI KAINNA
IPC: A42B3/04
Filed: 2019-10-04
Abstract: The invention relates to a helmet (1) having a hard shell (11) and a flexible shell (12) extending inside the hard shell, said helmet having an attachment device (13) for attaching an anti-theft system (14) external to the helmet. The attachment device comprises a ring (15) through which a connection element of said anti-theft system (14) external to the helmet is able to be passed, said ring (15) being mechanically connected to the hard shell (11) so as to be movable with respect to the hard shell (11) between a stowed position and an extended position; - in the stowed position, most of the ring (15) is located inside a cavity (16) at least partially delimited by the hard shell (11), and in the extended position, at least part of the ring (15) is located outside said cavity (16) so as to allow the connection element of the anti-theft system (14) to be passed through the ring.
Patent CA-3115563-A1 (CA)
Title: An inhalation system and a vapour generating article
Inventor: ROGAN ANDREW ROBERT JOHN
IPC: A24D1/20
Filed: 2019-10-17
Abstract: An inhalation system (1) for generating a vapour for inhalation by a user comprises an inhalation device (10) including a controller (20) and a vapour generating article (24, 50, 60, 90) comprising a vapour generating material (26) and a heating element (28, 52, 54, 62, 64). The vapour generating article has first and second regions (44, 46). The second region (46) contains one or more of a higher density of the vapour generating material (26) than the first region (44), vapour generating material (26) with a higher moisture content than the first region (44), or vapour generating material (26) with a higher aerosol-former content than the first region, and the heating element is arranged to generate more heat in the second region (46) than in the first region (44).
Patent CA-3115799-A1 (CA)
Inventor: GORDON RAPHAEL
IPC: A61M1/00
Filed: 2019-11-22
Abstract: Certain aspects of the present disclosure provide a surgical system comprising a pump motor configured to couple to a pump for pumping material through a probe, wherein the probe is connected to the pump through a connector. The surgical system also comprises a control module configured to determine a real-time flow rate through the probe and adjust a current pump rate of the pump to achieve a target flow rate, wherein the current pump rate is adjusted based on the real-time flow rate.
Patent CA-3117609-A1 (CA)
Title: System and device for irrigating and cleaning nasal cavities
Inventor: MOREAU DANY
IPC: A61M1/00
Filed: 2021-05-07
Abstract: A system for irrigating and cleaning nasal cavities is provided. In some embodiments, the system includes a stand configured to hold an aqueous solution container. A  primary incoming tube leading to a face mask device configured to be worn by a user. In one embodiment, the solution is gravity fed directed through the primary incoming tube into at least one port of the face mask device. A  drain line leads from the face mask device to a collection container.
Patent CA-3120432-A1 (CA)
Title: Crispr-cas12j enzyme and system
Inventor: LAI JINSHENG
IPC: A61K35/12
Filed: 2019-11-15
Abstract: Provided are a Cas effector protein, a fusion protein comprising said protein, and a nucleic acid molecule coding same. Also provided are a complex and a composition for nucleic acid editing, for example, a complex and a composition for gene or genome editing, comprising the Cas effector protein or the fusion protein, or the nucleic acid molecule encoding same. Also provided is a method for nucleic acid editing, for example, a method for gene or genome editing, using the Cas effector protein or the fusion protein.
Patent CA-3120751-A1 (CA)
Title: New form of isoquinoline sulfonamide
Inventor: HIDAKA HIROYOSHI
IPC: A61P27/06
Filed: 2019-12-16
Abstract: The purpose of the present invention is to acquire a stable crystal of a salt of N-[(R)-1-\{(S)-2-hydroxy-2-phenylpropylamino\}propan-2-yl]isoquinoline-6-sulfonamide, the crystal, as a material for medicines, having desirable properties. The salt is N-[(R)-1-\{(S)-2-hydroxy-2-phenylpropylamino\}propan-2-yl]isoquinoline-6-sulfonamide dihydrochloride anhydrate.
Patent CA-3121138-A1 (CA)
Title: Ophthalmic compositions and methods for the treatment of skin diseases and eye diseases
Inventor: KANDULA MAHESH
IPC: A61K9/00
Filed: 2019-11-23
Abstract: The invention relates to the compounds or its pharmaceutical acceptable polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, formula II, formula III and formula IV and the methods for the treatment of eye disorders and skin diseases and may be formulated for the topical eye drop, topical paste, ocular solution, device-drug delivery, oral, buccal, rectal, topical, transdermal, transmucosal, lozenge, spray, intravenous, oral solution, nasal spray, oral solution, cream, dermal ointment, gels, lotions, suspension, oral spray, buccal mucosal layer tablet, parenteral administration, syrup, or injection. Such compositions may be used to treatment of skin diseases and eye diseases.
Patent CA-3122287-A1 (CA)
Inventor: AMES JARED R
IPC: E02F9/28
Filed: 2019-12-17
Abstract: A wear member for earth working equipment, and a wear assembly including a plurality of such wear members, is described, The wear member defines a longitudinal axis and comprises: a body defining a rearward opening cavity dimensioned to receive a base; first and second lateral portions extending from opposing sides of the body and defining a front edge for engaging earth. The first lateral portion defines a complementary formation to the second lateral formation to enable axial insertion and removal of a wear member mounted between adjacent wear members due to the open removal path defined by the complementary formations. The complementary formations also resist rotational movement of the wear member about the longitudinal axis.
Patent CA-3123773-A1 (CA)
Inventor: KOLTAI HINANIT
IPC: A61K31/352
Filed: 2019-12-12
Abstract: L'invention concerne des compositions et des procédés pour le traitement d'un lymphome cutané à cellules T (CTCL). Les compositions et leurs utilisations comprennent des cannabinoïdes.