baber/WOPTO huggingface dataset:
Patent DE-69427990-D1 (DE)
Inventor: DELLA-CIOPPA GUY
IPC: C12N15/86
Filed: 1994-11-08
Granted: 2001-09-20
Abstract: The present invention relates to a nucleic acid sequence that encodes a fusion enzyme of tyrosinase and a tyrosinase activator protein. Further, the present invention also relates to the amino acid sequence which is encoded by the nucleic acid sequence of the fusion enzyme. The fusion enzyme may also include a linker positioned between the amino acid sequences of the tyrosinase and the tyrosinase activator protein. Still further, the present invention also relates to a vector useful for introducing the nucleic acid sequence encoding the fusion enzyme into an organism. Still further, the present invention relates to melanins made by the fusion enzyme and a method for making melanins using the fusion enzyme.
Patent DE-69428967-D1 (DE)
Inventor: JONASSON HALLGRIMUR
IPC: A61K47/44
Filed: 1994-07-01
Granted: 2001-12-13
Abstract: The present invention relates to novel oil-in-water emulsions especially suitable for parenteral administration of bioactive steroids which otherwise are difficult to solubilize in conventional solvents. The emulsions will comprise a lipid phase containing castor oil.
Patent DE-69429278-D1 (DE)
Inventor: OKAYAMA MINENOBU
IPC: C12N15/87
Filed: 1994-09-28
Granted: 2002-01-10
Abstract: A polyamino acid oligonucleotide carrier comprising a poly(lysine-serine) random copolymer. The carrier combines with an oligonucleotide without causing precipitation and releases the combined oligonucleotide smoothly in a cell. Hence it is useful as a carrier for in vivo transportation of a drug for oligonucleotide gene therapy against various types of genopathy and viral diseases such as AIDS. Further it contributes greatly to the creation of various useful animals and plants, such as virus-resistant plants, by genetic engineering techniques.
Patent DE-69434231-D1 (DE)
Inventor: ZEHAVI EPHRAIM
IPC: H04B1/707
Filed: 1994-11-01
Granted: 2005-02-17
Abstract: An improved system and method for communicating information at variable data rates over in-phase (I) and quadrature phase (Q) communication channels in a CDMA spread spectrum communication system is disclosed herein. In an exemplary implementation an input information signal is transmitted over either an I or Q communication channel using a direct sequence spread spectrum communication signal. The information signal is initially divided into first and second subsignals, which are respectively provided to first and second coset-encoding networks. The first coset-encoding combines the first subsignal with a first coset code, while the second coset-encoding network combines the second subsignal with a second coset code orthogonal to the first coset code. In this way the first and second coset-encoding networks are operative to produce first and second coset-encoded signals, respectively. A composite coset-encoded signal formed from the first and second coset-encoded signals is then modulated by an orthogonal function signal to provide a first modulated signal. In-phase pseudorandom noise (PNI) and quadrature phase pseudorandom noise (PNQ) signals of predetermined PN codes are used for spreading the first modulated signal for transmission to a receiver over either the I or Q communication channel, respectively. The receiver is operative to produce an estimate of the input information signal on the basis of the modulated carrier signal received over either the I or Q communication channel.
Patent DE-69500863-D1 (DE)
Inventor: BERGAMIN MIRCO
IPC: A43B19/00
Filed: 1995-04-18
Granted: 1997-11-20
Abstract: An innerboot, particularly for sports shoes such as ski boots or skates, includes a pair of overlapping flaps (6a,6b) at the front (2) and, at the rear (7), an opening (8a) having a tongue member (9). An innerboot is thus obtained that can be used for several kinds of shoes, even structurally different, such as front-entry, rear-entry, or central-entry boots. <IMAGE>
Patent DE-69512208-D1 (DE)
Inventor: TAKASE SHIGEHIRO
IPC: C07D471/04
Filed: 1995-01-23
Granted: 1999-10-21
Abstract: PCT No. PCT/JP95/00068 Sec. 371 Date Nov. 12, 1996 Sec. 102(e) Date Nov. 12, 1996 PCT Filed Jan. 23, 1995 PCT Pub. No. WO95/19959 PCT Pub. Date Jul. 27, 1995The present invention relates to a novel fatty acid derivative of the following formula: wherein R1 is acyl group, etc.; R2 is acyl(lower)alkyl; R3 is lower alkyl, etc.; R4 is hydrogen, etc.; and X is -O-, etc; and a pharmaceutically acceptable salt thereof, which is useful as a medicament; the processes for the preparation of said fatty acid derivative or a salt thereof; a pharmaceutical composition comprising said fatty acid derivative or a pharmaceutically acceptable salt thereof; etc.
Patent DE-69525186-D1 (DE)
Inventor: BUECHLER FRANCIS
IPC: G01N33/543
Filed: 1995-03-30
Granted: 2002-03-14
Abstract: Particles and methods for the detection or visualization of analytes using fluorescence energy transfer. Particles comprising an energy donor as a first component and a fluorescent dye as a second component positioned in said particles at an energy exchanging distance from one another, wherein the two components have a Stokes shift of greater than or equal to 50 nm, said particle having bound on its surface, a protein, polypeptide, nucleic acid, nucleotide or protein containing ligand analogue are disclosed and claimed.
Patent DE-69528530-D1 (DE)
Inventor: HELLINGS DEBORAH
IPC: A01K39/01
Filed: 1995-07-20
Granted: 2002-11-14
Abstract: The invention provides for an environmentally safe composition of a non-toxic, edible, biodegradable skeet (32) that is used for trap shooting. The skeet is designed so that it can be stacked as well as being able to withstand the throwing force of the trap. The skeet (32) is fabricated from a mixture of flour, water, and a non-toxic material. This non-toxic material can be an edible substance, such as birdseed (36), an additive such as fertilizer, or a combination of the substance and the additive. This composition of flour, water, and non-toxic material is placed in a mold and is baked to harden. The resulting skeet (32) is one which is easily breakable by a shotgun blast but able to withstand the throwing force of the trap. The design and shape of the skeet possesses an aerodynamic structure which permits the target (skeet) to be projected with considerable speed into the air.
Patent DE-69529393-D1 (DE)
Inventor: SHOHAM YAIR
IPC: H03M7/30
Filed: 1995-12-12
Granted: 2003-02-20
Abstract: The invention is used to shape noise in time domain and frequency domain coding schemes. The method advantageously uses a noise weighting filter based on a filterbank with variable gains. A method is presented for computing the gains in the noise weighting filterbank with filter parameters derived from the masking properties of speech. Illustrative embodiments of the method in various coding schemes are illustrated. <IMAGE>
Patent DE-69535063-D1 (DE)
Inventor: SAWAMURA ROSE
IPC: C12P21/02
Filed: 1995-11-30
Granted: 2006-07-27
Abstract: The present invention provides a DNA sequence essentially encoding a mammalian vascular endothelial receptor for modified low-density lipoprotein. The sequence is set forth in the Sequence No. 1, 2 or 3.
Patent DE-69619986-D1 (DE)
Inventor: ROLLER W
IPC: G02B6/42
Filed: 1996-07-12
Granted: 2002-04-25
Abstract: A removable light source is provided for use with the optical coupling system. The light source is mounted to a removable assembly for slidable insertion into, and removed from, a housing containing the optical coupling system. The removable assembly includes positioning elements for maintaining precise alignment of the light source with optical components mounted within the housing. In one embodiment described herein, precise alignment is achieved by employing six mounting pads on outside surfaces of a base of the removable assembly. Three of the mounting pads are aligned along a first plane. Two are aligned along a second plane perpendicular to the first. The remaining pad is aligned along a third plane perpendicular to both the first and second planes. The light source is mounted to the base in a precise fixed relationship with the mounting pads. The removable assembly is inserted within a slot formed in the housing of the optical coupling system. Upon insertion, the mounting pads lie against mutually perpendicular interior walls of a receiving block of the housing. The mounting pads thereby ensure that the light source is precisely positioned with respect to the receiving block. Optical components within the housing are mounted in a precise fixed relationship with the receiving block. Accordingly, while inserted, the light source is maintained in precise alignment with the receiving block and thereby also in precise alignment with the optical components.
Patent DE-69622695-D1 (DE)
Inventor: AZIZIAN FARID
IPC: C04B35/66
Filed: 1996-02-16
Granted: 2002-09-05
Abstract: PCT No. PCT/GB96/00362 Sec. 371 Date Nov. 28, 1997 Sec. 102(e) Date Nov. 28, 1997 PCT Filed Feb. 16, 1996 PCT Pub. No. WO96/25371 PCT Pub. Date Aug. 22, 1996A composition suitable for admixture with refractory grains to make a refractory monolithic formulation, consisting essentially of: 2 to 10 parts by weight of activated alumina; 0.25 to 1.0 parts by weight of an additive material which comprises at least one of an alumino-silicate-phosphate compound; a resin derived from an aldehyde and either an amine or an aromatic hydroxy compound; cellulose; polyethylene glycol(s); and methoxy polyethylene glycols; 0 to 50 parts by weight of fine alumina; 0 to 10 parts by weight of fine silica; 0 to 1 parts by weight of a dispersant; and 0 to 1 part by weight calcium aluminate cement.
Patent DE-69631376-D1 (DE)
Inventor: CHRIST J
IPC: A61P31/04
Filed: 1996-06-05
Granted: 2004-02-26
Abstract: Novel substituted liposaccharides useful as in the prophylactic and affirmative treatment of endotoxemia including sepsis, septicemia and various forms of septic shock and methods of using these agents are provided. Also provided are methods of preparing these agents and intermediates useful therein.
Patent DE-69633130-D1 (DE)
Inventor: EMOFF MICHAEL J
IPC: B65D23/14
Filed: 1996-08-12
Granted: 2004-09-16
Abstract: A pop-up coupon dispenser for small sheets which have a repositionable adhesive is provided with a flexible plastic cable tie. The dispenser includes a box filled with such sheets having an adhesive stripe along one margin and stacked in accordion fashion, the sheets being printed as manufacturer's coupons supplied to a retailer who attaches the box by the cable tie to a wire rack, to a cardboard display or other suitable support, such as a shelf, and cuts off the excess end of the cable tie. Customers can remove the coupons one-at-a-time and affix them by their adhesive backing to the product for which the coupon is redeemable. A check-out cashier can, therefore, immediately determine that the purchaser is purchasing the product for which the coupon was issued. The dispenser box may also be provided with a conventional shelf clip connected to the bottom of the dispenser box. Each coupon could comprise an unperforated sheet but could have a tear line adjacent the margin of the adhesive so that, in use, the customer can adhere the adhesively-coated portion of the coupon to the product to which the coupon applies. At the check-out counter, the cashier tears away the remainder of the label along the tear line. The torn-away portion, which is used by the retailer to redeem the coupon, will be easy for the check-out cashier and others to accumulate and handle. Also, the face of the sheet opposite the adhesively-coated portion may have advertising matter which the customer would take, because adhered to the purchased product, when leaving the retail store. In addition, a blinking LED could be housed within the dispenser box in alignment with an opening in the wall of the box to bring added attention to the dispenser box.
Patent DE-69635550-D1 (DE)
Inventor: ARMISTEAD M
IPC: A61K31/40
Filed: 1996-06-06
Granted: 2006-01-12
Abstract: The present invention relates to methods and pharmaceutical compositions for stimulating the growth of neurites in nerve cells. The compositions comprise a neurotrophic amount of a compound which binds to the FK-506 binding protein (FKBP) and a neurotrophic factor, such as nerve growth factor NGF. The methods comprise treating nerve cells with the above-described compositions or compositions comprising the FKBP binding compound without a neurotrophic factor. The methods of this invention can be used to promote repair of neuronal damage caused by disease or physical trauma.
Patent DE-69636037-D1 (DE)
Inventor: GRISEL E
IPC: A61K38/17
Filed: 1996-08-12
Granted: 2006-05-24
Abstract: The present invention relates to a novel mammalian anti-opioid receptor protein (OFQR), peptide ligands (such as OFQ) that bind to OFQR, and methods of using the OFQ peptide and analogues to reverse the physiologic effects of opiates such as morphine. The isolation, characterization and pharmacological use of the endogenous peptide ligand is described. A particular embodiment of the OFQ peptide is a heptadecapeptide having an FGGF aminoterminal motif. The peptide specifically binds to an OFQ receptor protein heterologously expressed in mammalian cells. The peptide does not bind with high affinity to  mu ,  delta  or  kappa  receptors, but it antagonizes opioid mediated effects (such as analgesia and hypothermia) without increasing nociceptive sensitivity. Tyrosine substitution variants of the peptide ligand specifically bind to the opioid receptor and can be radioiodinated. Also provided are methods of making such peptide ligands and OFQR antagonists, and methods of using the ligands for diagnostic and therapeutic uses and for the identification of other naturally-occurring or synthetic opioid receptor ligands.
Patent DE-69701406-D1 (DE)
Inventor: HADDAD ANEACE
IPC: G06Q30/00
Filed: 1997-01-21
Granted: 2000-04-20
Abstract: The memory of the credit/debit card contains: - a first identification file, called 'member file' which identifies the card owner; - a second posting file, called a 'points file'; - and a third file containing credit data about card owner for a number of shops/stores etc. at which the card owner makes transactions. The file contains, for each shop/store, a place identification code and several user purchase fields. The method actuates a given algorithm, as a function of the particular shop/store, at the moment a transaction is made, using the data contained in one or more of the fields relating to the shop/store and/or another shop/store. The data is then written into the 'points file' and in the third file, a receipt may be or may not be printed as a result of the actuation of the processing algorithm. For each commercial enterprise the third file fields include a register called 'activity code', identifying an activity sector. A specific processing algorithm is realized in the 'point file' at the time of a purchase at a particular enterprises as a function of the third file fields user by the card owner at one or more enterprises having the same 'activity code'. An Independent claim is included for a points/discount calculator.
Patent DE-69702397-D1 (DE)
Inventor: LEE J
IPC: D21F7/08
Filed: 1997-04-28
Granted: 2000-08-03
Abstract: A papermakers fabric, having top and bottom surfaces, woven from machine direction yarns and one layer of cross machine direction yarns. The cross machine direction yarns comprise relatively large and small yarns and the machine and cross machine direction yarns are arranged such that the machine direction yarns define floats on one of the surfaces of the fabric and knuckles below the one surface around small cross machine direction yarns. The parts of the machine direction yarns defining the knuckles below the one surface do not extend to the plane of the other surface of the fabric.
Patent DE-69704762-D1 (DE)
Inventor: BELK LEONARD
IPC: C09D9/00
Filed: 1997-02-10
Granted: 2001-06-13
Abstract: A paint remover formulation comprises a mixture of aqueous hydrogen peroxide solution and a paint removal accelerator. The accelerator comprises one or more of benzyl alcohol, ortho cresol, dipropylene glycol monomethylether, ethylene carbonate, and functional derivatives thereof. The paint remover formulation may include additives, such as thickeners and surfactants.
Patent DE-69706206-D1 (DE)
Inventor: FAUCHERE JEAN-LUC
IPC: A61K31/41
Filed: 1997-02-10
Granted: 2001-09-27
Abstract: Pseudopeptide neurokinin derivatives of formula (I), their enantiomers, diastereomers, epimers and acid or base addition salts are new. R1 = indolyl, naphthyl, tetrahydronaphthyl, thienyl, Ph (optionally substituted by one or more halo, 1-6C alkyl, 1-6C alkoxy, OH or trihalomethyl) or 3-7C cycloalkyl; n = 1-8; m = 1-4; and R2 = benzyl or Ph (both optionally substituted by one or more halo, 1-6C alkyl, 1-6C alkoxy, OH or trihalomethyl) or 1-6C alkyl.
Patent DE-69716693-D1 (DE)
Inventor: LOUBEYRE PATRICK
IPC: B24C7/00
Filed: 1997-09-24
Granted: 2002-12-05
Abstract: The control, for equipment which uses compressed air or water at pressure with a fine grained abrasive material to clean contaminated surfaces, is mounted on a single hand held pistol with trigger (2) which incorporates a mixer and nozzle (3). Water at high pressure is delivered to the pistol (2) through a pump (1) and pipe (E1). An air compressor (4) supplies air to a material tank (6) and sends an air/material mixture to the mixer (3) by Venturi effect. Water is controlled by the pistol trigger and a lever on the same pistol controls the flow of material using a tank valve (V1) and pipe (A7).
Patent DE-69716927-D1 (DE)
Inventor: BINDRA AMRIT
IPC: C09B63/00
Filed: 1997-07-18
Granted: 2002-12-12
Abstract: Disclosed are compositions comprising one or more compounds characterized by the formula: wherein each R is independently a hydrocarbyl, hydroxy, hydrocarbyloxy, carboxylic acid, carboxylic acid ester, carboxylic acid amide, sulfonic acid, sulfonic acid amide, imidazolone or nitro group; n is 0, 1 or 2; and M is at least one divalent metal. A process for preparing azo pigment compositions is also disclosed. Paint, ink and plastic compositions containing the foregoing pigments compositions are disclosed.
Patent DE-69731179-D1 (DE)
Inventor: GEE R
IPC: G01N1/30
Filed: 1997-04-11
Granted: 2004-11-18
Abstract: The family of dyes of the invention are fluoresceins and rhodols that are directly substituted on one or more aromatic carbons by fluorine. These fluorine-substituted fluorescent dyes possess greater photostability and have lower sensitivity to pH changes in the physiological range of 6-8 than do non-fluorinated dyes, exhibit less quenching when conjugated to a substance, and possess additional advantages. The dyes of the invention are useful as detectable tracers and for preparing conjugates of organic and inorganic substances.
Patent DE-69738352-D1 (DE)
Inventor: BRACCO LAURENT
IPC: A61K31/711
Filed: 1997-10-27
Granted: 2008-01-17
Abstract: The invention concerns single-chain antibodies directed against the p53 protein, capable of being expressed in tumoral cells, capable of restoring a DNA binding in vitro and a transcription activator function in vivo. The invention also concerns nucleic acids coding for these molecules, the vectors containing them and their uses.
Patent DE-69738948-D1 (DE)
Inventor: BENDELE ALISON M
IPC: A61P43/00
Filed: 1997-12-08
Granted: 2008-10-09
Abstract: The invention relates to methods for treating or preventing arthritis. The method comprises administering to patients in need thereof therapeutically effective amounts of an IL-1 inhibitor and methotrexate. In a preferred embodiment, the IL-1 inhibitor is human recombinant IL-1ra and the methotrexate is N-{4-[(2,4-diamino-6-pteridinyl)methylamino]benzoyl]-L-glutamic acid. The invention also relates to pharmaceutical compositions containing an IL-1 inhibitor and methotrexate useful in such methods.
Patent DE-69803947-D1 (DE)
Inventor: ROSSMANN ALAIN
IPC: H04W88/02
Filed: 1998-03-12
Granted: 2002-04-04
Abstract: A structured screen display process presents structured information that includes a plurality of elements on any width screen display so that the user is able to see as many of the elements as possible at once, and is able to see the complete text of any element as needed. The process dynamically adapts the display of structured infomation to the screen display width of the device. Further, in this dynamic adaption, the user sees at a glance as many as possible of the elements of the structure, and the user can see any of the elements at the user's discretion in a way which is compatible with using structured information such as a menu of choices. The structured information is presented on a screen display by displaying at least a portion of each element in a plurality of elements on the screen display where at least one of the elements has a width greater than a width of the screen display. The at least one element is scrolled horizontally while continuing to display the portion of each other element in the plurality of elements.
Patent DE-69812109-D1 (DE)
Inventor: THOREN AGNETA
IPC: A61F13/472
Filed: 1998-06-18
Granted: 2003-04-17
Abstract: A fluid permeable covering sheet (301) for an absorbent article such as a diaper, an incontinence protector, a sanitary napkin, or the like, comprising an apertured, textile sheet of material (9) comprising at least one thermoplastic component. The covering sheet (301) exhibits a substantially two-dimensional structure with a plurality of apertures (204,208) each surrounded by an essentially fluid impermeable edge (206) consisting of an essentially smooth plastic surface in the plane of the material. <IMAGE>
Patent DE-69812402-D1 (DE)
Inventor: FERRARO DANIELA MONICA CATERIN
IPC: B65D21/02
Filed: 1998-11-25
Granted: 2003-04-24
Abstract: A food container is superimposed onto the upper end of a beverage receptacle. The container has a side wall and bottom wall in which there is formed at least one channel to allow the passage out through the container of a drinking straw which penetrates into the receptacle. The bottom wall is provided with a plurality of connectors for allowing connection of the food container to receptacles of different sizes at their upper end.
Patent DE-69812924-D1 (DE)
Inventor: ALLINGHAM PAUL
IPC: B01D46/02
Filed: 1998-10-22
Granted: 2003-05-08
Abstract: The disclosed apparatus is a filter bag cage which is modularly constructed from end caps, circumferential rings (circular or other shapes), and longitudinal wires which are individually manufactured with fastening joints to allow for later assembly. These components may be subsequently shipped and stored as an unassembled bundle and not assembled until reaching the point of use.
Patent DE-69816300-D1 (DE)
Inventor: TOPOROV YOURI GENADIEVICH
IPC: A61M36/12
Filed: 1998-10-30
Granted: 2003-08-14
Abstract: The method comprises the steps of forming an elongated tubular metal casing 1. This elongated tubular metal casing 1 is then coiled. The coiled tubular casing 11 is filled with a material 9 capable to irradiate radioactive radiation. The material 9 is in liquid state with following crystallization in the coiled tubular casing 11. The filled coiled tubular casing 11 is then sealed at its ends 5. <IMAGE>
Patent DE-69818650-D1 (DE)
Inventor: TERSTAPPEN W
IPC: G01N33/553
Filed: 1998-03-24
Granted: 2003-11-06
Abstract: Apparatus and methods are disclosed which facilitate immobilization of magnetically labelled particulate entities, e.g., cells, preferably in a defined pattern, on a collection surface via binding between specific binding pair members, as an aid to particle analysis.
Patent DE-69825473-D1 (DE)
Inventor: ADELMAN BURT
IPC: A61K38/27
Filed: 1998-06-19
Granted: 2004-09-09
Abstract: Methods and compositions for attenuating or mitigating; suppressing; preventing; delaying onset of; or, reversing exogenous protein inhibitor syndromes, exemplified by clotting factor (e.g., Factor VIII) inhibitor syndromes. The described methods use a CD40:CD154 binding interrupter, such as a CD154 blocking agent, to attenuate or ameliorate counter-adaptive, bioinhibitory humoral immunity directed against an exogenous protein of therapeutic value.