baber/WOPTO huggingface dataset:
Patent CA-3098291-A1 (CA)
Title: Composes tetrahydro-1h-pyrazino[2,1-ajisoindolylquinoline pour le traitement d'une maladie auto-immune
Inventor: DEY FABIAN
IPC: C07D417/14
Filed: 2019-06-03
Abstract: La présente invention concerne des composés de formule (I), dans laquelle R1 à R6, m et n sont tels que décrits dans la description, et leurs sel, énantiomère ou diastéréoisomère pharmaceutiquement acceptables, et des compositions comprenant les composés et des procédés d'utilisation des composés.
Patent CA-3098518-A1 (CA)
Inventor: KUKKONEN ESKO
IPC: B60C11/16
Filed: 2019-06-05
Abstract: A method for making a blind hole in a prefabricated tire and a method for inserting an insert to such a blind hole are disclosed. The former comprises arranging available a prefabricated tire comprising tread blocks forming the tread of the tire, and thereafter machining such a blind hole to a tread block of the tire that the blind hole has a first cross section at a first depth and a second cross section at a second depth, wherein the second cross section is greater than the first cross section and the second depth is greater than the first depth.
Patent CA-3098809-A1 (CA)
Inventor: BILLINGS JOHN
IPC: C02F1/00
Filed: 2019-04-23
Abstract: Systems and methods for remediating hull wastewater are described herein. The systems include: a separation unit for separating a hull wastewater feed stream into a separated feed stream and a first solid waste stream, a filtration unit coupled to the separation unit for filtering the separated feed stream into a filtered stream and a second solids waste stream; a membrane filtration unit coupled to the filtration unit for membrane filtering the filtered stream into a membrane filtered stream and a third solids waste stream; an inactivation unit coupled to the membrane filtration unit for inactivating the membrane filtered stream into a final product stream; and a waste removal unit coupled to the separation unit and the filtration unit for receiving and dewatering the first solids waste stream and the second solids waste stream into a recycle stream and a waste product stream.
Patent CA-3099641-A1 (CA)
Title: Dental band device
Inventor: LO BRIAN
IPC: A61C5/85
Filed: 2020-11-16
Abstract: Dental matrix band devices including a housing with a band, a tensioning device for the band with the control for the tensioning mechanism controllable by a control knob external to the housing. and at least one deflector pushbutton. The deflector pushbutton(s) applies pressure on an upper or lower portion of the band causing the geometry of the band to change. The resulting band geometry forms a conical loop better matching the configuration of a tooth. In one embodiment two deflector pushbuttons are provided and positioned to apply pressure on the upper or lower portion of the band depending on which deflector pushbutton is depressed in the housing. In another embodiment a single deflector pushbutton unit is provided with a pushbutton at each end.
Patent CA-3100704-A1 (CA)
Title: Sliding closure for a metallurgical vessel, preferably a distributor vessel for a continuous casting facility
Inventor: HEINRICH BEAT
IPC: B22D41/34
Filed: 2019-04-23
Abstract: The invention relates to a sliding closure for a metallurgical vessel, having two compensation units I and II to compensate for overloads which can result from the thermal expansion and from production-induced scatter of the fire-resistant closure plate thicknesses and/or the upper inner sleeve, wherein the inner sleeve can also be lowered during operation. Compensation unit I comprises a spring assembly (23) having fixing screws (15a, 15b) that can be pivoted away between the housing (4) and a cover (11) of the housing. Compensation unit II for its part comprises a spring assembly (30) having an insert frame (25) that presses against the lower closure plate (6) and which spring assembly is fixed to the underside of the housing (4) by fixing screws (26).
Patent CA-3102381-A1 (CA)
Inventor: LIU FANG-YU
IPC: A61K31/505
Filed: 2019-06-13
Abstract: The present invention relates to kinase inhibitor C8-C16 aliphatic sulfate salts and compositions thereof.
Patent CA-3102412-A1 (CA)
Title: Methodes de traitement de sujets atteints de diabete avec une maladie renale chronique
Inventor: SYMONDS BILL
IPC: A61P3/10
Filed: 2019-06-06
Abstract: La présente invention concerne une méthode de traitement du prédiabète ou du diabète sucré de type 1 ou de type 1 ou de type 2 comprenant l'administration à un sujet qui en a besoin d'une quantité efficace d'iméglimine, le sujet ayant une maladie rénale chronique.
Patent CA-3103280-A1 (CA)
Inventor: YU ZHENPENG
IPC: C07D207/27
Filed: 2018-12-17
Abstract: L'invention concerne un procédé de préparation d'un intermédiaire de lactame et de brivaracétam de haute pureté chirale. L'invention concerne un procédé de préparation d'un composé intermédiaire de lactame représenté par la formule moléculaire D, le procédé comprenant une étape de réduction d'un composé C en un intermédiaire de lactame D dans un solvant par réduction d'hydrogénation à l'aide d'un catalyseur de métal lourd et d'un inducteur chiral. Le brivaracétam peut être préparé en une seule étape à l'aide du composé intermédiaire de lactame représenté par la formule moléculaire D selon la présente invention. La voie de synthèse est courte, les conditions de réaction sont modérées, le post-traitement est simple, le rendement de réaction est élevé, la sélectivité chirale est bonne, et le coût de production est faible. Le taux de conversion du composé C dans la réaction est de 81 %, et la valeur DE du composé D est supérieure à 99,0 %, ce qui est approprié pour une production industrielle.
Patent CA-3106492-A1 (CA)
Inventor: MANNESCHI ALESSANDRO
IPC: G01V3/10
Filed: 2019-07-15
Abstract: The invention concerns a combined detector (1) comprising: - an active metal detection system (10) comprising: ¦ at least two vertical posts (12) together defining a transit channel and ¦ windings (14, 15) distributed in the two vertical posts (12) configured to emit an alternating magnetic field and designed to generate a signal representative of a perturbation of the magnetic field induced when an individual passes between the two vertical posts (12), - at least one passive metal detection system (20) comprising at least one static magnetostatic sensor (22) configured to generate a signal indicative of an intensity of a static magnetic field, the passive detection system (20) being housed in one of the vertical posts (12).
Patent CA-3106719-A1 (CA)
Title: Systeme d'evaluation et de valorisation de presentation
Inventor: SCHOLZ BRIAN A
IPC: G06F3/048
Filed: 2019-09-23
Abstract: L'invention concerne un système d'évaluation et de valorisation de présentation interactive mis en uvre par ordinateur proposant un ordinateur serveur qui permet à un ou plusieurs dispositifs informatiques d'accéder à un système d'évaluation et de valorisation de présentation qui fournit un analyseur de présentation qui applique des algorithmes de notation normalisés aux données vidéo ou aux données audio associées à une présentation et qui génère de manière correspondante des scores normalisés de débit de mots, de clarté de mots, de mots de remplissage, de ton, ou de contact oculaire, et qui calcule un score de présentation sur la base d'une moyenne ou d'une moyenne pondérée des scores.
Patent CA-3107178-A1 (CA)
Inventor: CAMUS CHRISTOPHE
IPC: B65D85/50
Filed: 2019-07-22
Abstract: The present invention concerns a device (1) for transporting a bouquet of flowers (2), comprising :- a polyhedral body (3), - the polyhedral body having at least one facet (4A, 4B, 4C) and at least three longitudinal edges (10A, 10B, 10C), - said facet comprising at least one upper facet (4A), at least one intermediate facet (4B) and at least one lower facet (4C), said intermediate facet (4B) comprising at least one lower intermediate rib (7B) and at least one upper intermediate rib (7A), - said intermediate facet (4B) comprises at least one longitudinal slot (5A, 5B, 5C) between each intermediate facet (4B) and at least three parallel fold lines (6A, 6B, 6C), said parallel fold lines comprising an upper fold line (6A), an intermediate fold line (6B) and a lower fold line (6C), the slot (5A, 5B, 5C) and the fold lines (6A, 6B, 6C) defining said upper intermediate rib (7A) and said lower intermediate rib (7B), - said lower intermediate rib (7B) being connected to said upper intermediate rib (7A) at the intermediate fold line (6B), characterised in that - in the device in the locked form, said lower (7B) and upper (7A) intermediate rib is adjacent to a first lower (7D) and upper (7C) intermediate rib and to a second lower (7L) and upper (7K) intermediate rib respectively, - and said lower (7B) and upper (7A) intermediate rib is positioned respectively above said first upper intermediate rib (7C) and below said second lower intermediate rib (7L) by overlapping respectively, so as to form a self-supporting structure suitable for locking the device and for keeping the stems of the bouquet of flowers in vertical position inside the device.
Patent CA-3108104-A1 (CA)
Inventor: BAO WEI
IPC: H04W76/18
Filed: 2019-07-19
Abstract: Provided in the present disclosure is a redistribution method and terminal, which solve the problem of the transmission currently carried out by a UE needing to be stopped during the process of re-establishing an RRC connection. The processing method of the present disclosure comprises: when the wireless connection between a terminal and a master node (MN) is lost, reporting an MN wireless connection lost indication to a secondary node (SN); if an RRC redistribution message is received before a target timer times out, carrying out redistribution processing according to said RRC redistribution message.
Patent CA-3110491-A1 (CA)
Inventor: TAN MELVIN
IPC: G06Q10/00
Filed: 2019-08-26
Abstract: L'invention concerne un procédé d'obtention à distance d'informations de donneur, comprenant l'identification d'un donneur après avoir reçu des informations propres au donneur du donneur à distance et la récupération, au niveau d'un centre de collecte de plasma, d'un questionnaire de donneur fondé, au moins en partie, sur les informations propres au donneur. Le procédé peut ensuite présenter au moins une question issue du questionnaire au donneur à distance et recevoir au moins une réponse à la question ou aux questions du donneur. À la réception de la ou des réponse(s), le procédé traite la ou les réponse(s) au centre de collecte de plasma et évalue un résultat des réponses traitées afin d'obtenir une évaluation des résultats en fonction de ladite réponse. L'évaluation peut soit être soit une évaluation réussie soit une évaluation ratée. Le procédé peut ensuite coder l'évaluation, si l'évaluation est une évaluation réussie, et fournir l'évaluation codée au donneur.
Patent CA-3110678-A1 (CA)
Title: Apparatus and method for assessing emotion of infants and young children
Inventor: COUBART AURELIE
IPC: A61B5/377
Filed: 2019-08-30
Abstract: A system and apparatus for collecting electroencephalography (EEG) data from infants and young children is disclosed. An apparatus comprises an EEG headset and a plurality of EEG electrodes disposed on the cap in an arrangement having frontal, temporal, and parietal symmetry. The plurality of EEG electrodes is configured to contact a scalp of an infant or a young child and provide a stimulus.
Patent CA-3111700-A1 (CA)
Inventor: SEGALL KEVIN I
IPC: A23L11/00
Filed: 2010-01-25
Abstract: ABSTRACT  A soy protein product having a protein content of at least 60 wt% (N x 6.25) d.b., preferably an isolate having a protein content of at least about 90 wt% (N x 6.25) d.b., is formed from the supernatant from the precipitation of a soy protein micellar mass. A  calcium salt or other divalent salt is added to the supernatant, before concentration, after initial concentration or after final concentration, to provide a conductivity of about 2 to about 30 mS.  Precipitate is removed from the resulting solution and the pH of the clear soy protein solution is optionally adjusted to about 1.5 to about 4.4. The optionally pH-adjusted clear solution is concentrated to a concentration of about 50 to about 400 g/L and the clear concentrated protein solution is optionally diafiltered prior to drying. The soy protein product is soluble in acidic media and produces transparent, heat stable solutions at low pH values and, therefore, may be used for protein fortification of soft drinks and sports drinks. Date Recue/Date Received 2021-03-10
Patent CA-3113775-A1 (CA)
Inventor: NORDIN JESPER
IPC: G10H1/26
Filed: 2019-09-24
Abstract: The invention relates to a virtual instrument for real-time musical generation, comprising a musical rule set unit (7) for defining musical rules, a time constrained pitch generator (9) for synchronizing generated music, an audio generator (11) for generating audio signals (10), wherein the rule definitions describe real-time morphable music parameters, and said morphable music parameters are controllable directly by the real-time control signal (2). With this virtual instrument, the user can create new musical content in a simple and interactive way regardless of the level of musical training obtained before using said instrument.
Patent CA-3115853-A1 (CA)
Inventor: BERNARDS STEPHANIE
IPC: G01N1/02
Filed: 2021-04-20
Abstract: Described herein is a contact plate for microbial testing and sampling of comer surfaces.  The contact plate may comprise a base having a first side and a second side.  The first side may have a first wall and a second wall extending outward from the first side of the base to form a comer and define a surface for collecting biological samples. Additionally, the contact plate may include a rectangular lid configured to secure around the first wall and the second wall, and/or a handle removably coupled to the second side of the base.
Patent CA-3118959-A1 (CA)
Title: Metal oxides nanoparticles conjugated with naphthalene derivatives as contrast agents for the detection of .beta.-amyloid plaques by magnetic renosance images (mri)
Inventor: RODRIGUEZ-TANTY CHRYSLAINE
IPC: A61K49/18
Filed: 2019-05-13
Abstract: This invention is directed to metal oxide nanoparticles of the general formula (I) wherein : wherein R 1; is an organic coating to the metal oxide core, of polymeric type, catechol derivatives and trialkoxyalkylaminosilane; R 2 : -NHCO-alkylenyl-C(0)NH-alkylenyl-R 3; R 3 : -COO-, -CO-, -NH, -0-, -S-, -NH-alkylenyl-NH-, -NR 4-CSS-; R 4 : -H, -CH 3, -CH 2-CH 3, -CH 2CH 2CH 3, and M x0 y : iron oxide (Fe 3O 4 / gamma Fe 20 3), gadolinium oxide (III), manganese oxide (II) and copper (II) oxide; wherein the conjugated, functionalized and coated magnetic nanoparticle is capable of, when it is administered to a mammal, crossing the blood-brain barrier and specifically binding to the agglomerates and amyloid plaques present in brain tissue, and wherein with this nanoparticle bound to the agglomerates and beta- amyloid plaques in the brain tissue, hypo- or hyper-intense signals are observed in the region of interest through magnetic resonance imaging (MRI). The nanoparticles of formula I are capable of acting as positive (T1) and/or negative (T2) contrast agents for MRI for the early and non-
Patent CA-3119855-A1 (CA)
Inventor: YE KONGMENG
IPC: A01D34/13
Filed: 2018-08-21
Abstract: The present invention provides a switchable cutting blade paired with a harvester knife guard. The switchable cutting blade comprises a switchable cutting blade assembly comprising a cutting bucket steel plate and a plurality of cutting blade bottom frames fixed on the cutting bucket steel plate. Each cutting blade bottom frame comprises a triangular part and a groove frame integrated with the triangular part. The triangular part protrudes from a front end of the groove frame along a direction perpendicular to an upper surface of the groove frame. Each two adjacent cutting blade bottom frames are fixed by a crossbar. Each cutting blade bottom frame is provided with a cutting blade component comprising a blade part and a mounting part arranged at a rear end of the blade part. Each mounting part comprises a groove fixed on the corresponding groove frame.
Patent CA-3122146-A1 (CA)
Inventor: JONES CHRISTOPHER MICHAEL
IPC: E21B33/127
Filed: 2019-03-21
Abstract: L'invention concerne une cheminée de pompe à siphon qui peut être utilisée dans un essai de mini-tige de forage pour augmenter les débits de fluide de formation. Un testeur de formation peut être accouplé à une cheminée de pompe à siphon par le biais d'un ensemble de raccordement par voie humide pour transférer un fluide de formation à partir d'une formation portant un fluide. La cheminée de pompe à siphon peut recevoir le fluide de formation à travers le raccordement par voie humide et disperser le fluide de formation dans un tube de forage dans lequel s'écoule le fluide de forage. La cheminée de pompe à siphon peut comprendre des clapets anti-retour pour empêcher le fluide de forage de pénétrer dans la cheminée de pompe à siphon. La cheminée de pompe à siphon peut être configurée pour présenter une hauteur variable qui peut réduire la pression à l'intérieur de la cheminée de pompe à siphon jusqu'à une valeur de pression qui peut être proche de la pression de formation ou inférieure à celle-ci, ce qui peut permettre à une pompe de fonctionner à des débits élevés ou d'être contournée dans une configuration à écoulement libre.
Patent CA-3123351-A1 (CA)
Title: Antifolate-carrying nanoparticles and their use in medicine
Inventor: MCATEER MARTINA
IPC: A61P35/00
Filed: 2019-12-13
Abstract: The present invention provides a nanoparticle comprising: a core comprising a metal and/or a semiconductor; and a plurality of ligands covalently linked to the core, wherein said ligands comprise: (i) at least one dilution ligand comprising a carbohydrate, glutathione or an ethylene glycol-containing moiety; and (ii) a ligand of the formula D-L1-Z-L2, wherein D comprises an antifolate drug or folic acid, L1 comprises a first linker portion comprising a C2-C12 glycol and/or C2-C12 alkyl chain, L2 comprises a second linker portion comprising a C2-C12 glycol and/or C2-C12 alkyl chain, wherein L1 and L2 may be the same or different, and wherein Z represents a carbonyl-containing group linking L1 and L2, and wherein L2 is coupled to said core, Also provided are pharmaceutical compositions comprising such nanoparticles, medical uses thereof and methods for producing the nanoparticles.
Patent CA-3123487-A1 (CA)
Title: Single phase fault isolation and restoration with load estimation
Inventor: KELLER ERICH
IPC: H02H7/26
Filed: 2021-06-28
Abstract: A processor receives an indication of a fault from a first isolation device.  The processor sends a first open command to a downstream isolation device downstream of the fault, identifies a tie-in isolation device, and identifies a line section without current monitoring positioned between the tie-in isolation device and the downstream isolation device. The line section has a plurality of line segments, each having a load rating. The processor receives incoming and exiting current measurements for the line section and estimates a first current load for each of the line segments in the line section based on the incoming and exiting current measurements and the load ratings. The processor selects an intermediate isolation device between the tie-in isolation device and the downstream isolation device based on the first current loads, sends a second open command to the intermediate isolation device, and sends a close command to the tie-in isolation device.
Patent CA-3124904-A1 (CA)
Title: Focused rotary jet spinning devices and methods of use thereof
Inventor: LIU QIHAN
IPC: D01D5/18
Filed: 2020-01-14
Abstract: Systems and methods for focused direction deposition of a micron or nanometer dimension polymeric fiber and materials of such fibers are described herein. Systems and methods employ one or more gas flows to entrain and deflect fibers produced by a rotary jet spinning system forming a focused fiber stream. Some embodiments enable control of alignment and distribution of the fibers with a relatively high fiber throughput.
Patent CA-3125689-A1 (CA)
Inventor: WEHKAMP JAN
IPC: A61K38/08
Filed: 2020-01-07
Abstract: La présente invention concerne de nouveaux peptides issus de HD-5 ou de HNP-4 présentant une activité antimicrobienne pour une utilisation dans la modulation du microbiome des intestins, des poumons, de la peau, de la bouche, de l'il, de l'oreille, du vagin ou d'autres surfaces corporelles et/ou pour une utilisation en tant qu'agent antimicrobien chez un être humain ou d'autres mammifères, ainsi que des médicaments contenant ces peptides.
Patent CA-3126269-A1 (CA)
Title: Coloring of lead or steel hunting/sporting shots and its method
Inventor: YAVAS HASAN
IPC: F42B12/80
Filed: 2019-12-25
Abstract: The invention comprises the process of cleaning the surface of lead or steel shot (10) in the drum system and increasing the surface area to allow the epoxy (20) to adhere to the surface and spraying and cooking the paint to the surface with the spray gun in the drum system.
Patent CA-3127643-A1 (CA)
Title: Optical device for light delivery
Inventor: BROOKER JEFFREY S
IPC: G02B26/08
Filed: 2020-01-30
Abstract: An optical device includes: first and second optical paths; a light reflective surface; and a linkage system. The first optical path is defined along a first optical axis. The second optical path is defined along a second optical axis. The light reflective surface is defined between the first and second optical paths. The first and second axes define first and second tilt angles from a normal line of the reflective surface, respectively. The linkage system connects the first and second optical paths with the light reflective surface such that the first tilt angle remains the same as the second tilt angle during movement of the first optical path relative to the second optical path.
Patent CA-3128578-A1 (CA)
Title: Microfluidic chip for attracting and destroying a specific biological element
Inventor: CHARLOT BENOIT
IPC: A61N1/40
Filed: 2020-03-12
Abstract: The present invention relates to a microfluidic chip for attracting and destroying a specific biological element, said chip comprising: - a reservoir (1) consisting of a matrix comprising a chemoattractant compound capable of attracting the biological element; - at least one set of microchannels (2) arranged between the reservoir (1) and the external environment (3) of the chip and allowing the chemoattractant compound to move toward said medium and the biological element present in said medium to move in the direction of the reservoir (1); - at least one electrode (4) arranged between the reservoir (1) and the set of microchannels (2) or at the same location as the set of microchannels (2), said electrode (4) being capable of generating an electric field so as to destroy the biological element as it moves toward the reservoir (1).
Patent CA-3129868-A1 (CA)
Title: Systems, compositions, and methods for target entity detection
Inventor: SEDLAK JOSEPH CHARLES
IPC: C12Q1/6804
Filed: 2020-02-28
Abstract: The present disclosure provides technologies for target entity detection. One aspect of the present disclosure provides technologies for detection (e.g., early detection) of a disease, disorder, or condition (e.g., cancer). In another aspect, technologies provided herein are useful for selecting and/or monitoring and/or evaluating efficacy of, a treatment administered to a subject in need thereof, e.g., a subject determined to have or susceptible to cancer. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g., by measuring tumor burdens and changes in tumor burdens in conjunction with therapeutics.