baber/WOPTO huggingface dataset:
Patent EP-3912642-A1 (EP)
Inventor: VAN DELFT FLORIS LOUIS
IPC: A61K47/68
Filed: 2013-10-23
Abstract: The present invention relates to an antibody comprising a GlcNAc-S(A)<sub>x</sub> substituent, wherein S(A)<sub>x</sub> is a sugar derivative comprising x functional groups A wherein A is independently selected from the group consisting of an azido group, a keto group and an alkynyl group and x is 1, 2, 3 or 4, wherein said GlcNAc-S(A)<sub>x</sub> substituent is bonded to the antibody via C1 of the N-acetylglucosamine of said GlcNAc-S(A)<sub>x</sub> substituent, and wherein said N-acetylglucosamine is optionally fucosylated.The invention also relates to an antibody-conjugate, in particular to an antibody-conjugate according to the Formula (20) or (20b), wherein AB is an antibody, S is a sugar or a sugar derivative, D is a molecule of interest, and wherein said N-acetylglucosamine is optionally fucosylated (b is 0 or 1).The invention further relates to a process for the preparation of a modified antibody, to a process for the preparation of an antibody-conjugate, and to said antibody-conjugate for use as a medicament.In addition, the invention relates to a kit of parts comprising an azide-modified antibody and a linker-conjugate, wherein said linker-conjugate comprises a (hetero)cycloalkynyl group and one or more molecules of interest.
Patent EP-3907430-A1 (EP)
Inventor: KRISTEN VINCENT
IPC: F21V35/00
Filed: 2021-05-07
Abstract: The current invention relates to a candle holder comprising a bottom, an opposite open side and a wall, wherein the bottom comprises a wick-positioning means, configured for the fixed positioning of a wick holder of a candle in the candle holder. The invention also relates to a candle suited to be used in accordance with said candle holder, wherein the candle comprises a wick and wherein the candle is able to form-fitting fit in said candle holder.
Patent EP-3922225-A1 (EP)
Inventor: SABLONE GABRIELE
IPC: A61F13/15
Filed: 2021-05-21
Abstract: A method and apparatus for producing pant-like absorbent sanitary articles with longitudinal elastic bands (28) without side welds and wherein the length of the elastic bands (28) is different from the length of the absorbent body (12).
Patent EP-3978512-A1 (EP)
Inventor: AZIMI NAZLI
IPC: A61P35/00
Filed: 2016-10-06
Abstract: Embodiments relate to peptide antagonists of yc-family cytokines, which is associated with important human diseases, such as leukemia, autoimmune diseases, collagen diseases, diabetes mellitus, skin diseases, degenerative neuronal diseases and graft-versus-host disease (GvHD). Thus, inhibitors of yc-cytokine activity are valuable therapeutic and cosmetic agents as well as research tools. Traditional approaches to inhibiting yc-cytokine activity involve raising neutralizing antibodies against each individual yc-cytokine family member/ receptor subunit. However, success has been limited and often multiple yc-cytokine family members co-operate to cause the disease state. Combinatorial use of neutralizing antibodies raised against each factor is impractical and poses an increased risk of adverse immune reactions. The present embodiments overcome these shortcomings by utilizing peptide antagonists based on the consensus yc-subunit binding site to inhibit yc-cytokine activity. Such approach allows for flexibility in antagonist design. In several embodiments, peptides exhibit Simul-Block activity, inhibiting the activity of multiple yc-cytokine family members.
Patent EP-3896479-A1 (EP)
Inventor: YUN DOOHEE
IPC: H04W64/00
Filed: 2014-04-14
Abstract: A system and method for providing localization of a mobile electronic device within an environment includes at least one server in communication with the mobile electronic device. The at least one server is adapted to receive at least one picture and at least one accelerometer measurement from the mobile electronic device. The at least one server includes a localization module that provides localization to the mobile electronic device based on the at least one picture, the at least one accelerometer measurement and on at least one 3-dimensional map of the environment.
Patent EP-3923322-A1 (EP)
Inventor: KRESS HARALD
IPC: H01L23/498
Filed: 2021-06-02
Abstract: Die Erfindung betrifft ein Modul (1), bei dem Spannungen größer als 1.000 V und Ströme größer als 100 A über Zuleitungen angelegt werden, mit einem elektrisch isolierenden Träger (2), mit einem Anschlussmittel (3) mit einer Materialdicke größer als 0,3 mm, welches über einen Metallisierungsbereich (4), der von einem ersten Ende (23) und einem zweiten Ende (24) begrenzt ist, mit dem Träger (2) verbunden ist, mit elektronischen Komponenten (19, 20), die mit dem Anschlussmittel (3) je nach Bedarf elektrisch verbunden sind und mit Kühlmittel (14).Damit die Stromzuführung von außen über das Anschlussmittel (3) direkt an das Modul erfolgt und somit die im Stand der Technik üblichen Bondprozesse entfallen und dadurch parasitäre Induktivitäten an der Stromzuführung vermieden werden, wird erfindungsgemäß vorgeschlagen, dass das Anschlussmittel (3) an zumindest einer Stelle über ein Ende (23, 24) des Metallisierungsbereichs (4) ragt, und in diesem Bereich (9) nicht mit dem Träger (2) fixiert ist und Kontaktmittel (22) aufweist.
Patent EP-3932256-A1 (EP)
Title: System, umfassend eine möbeltüreinheit und ein einbauhaushaltsgerät, sowie verfahren zum betrieb des systems
Inventor: STECKER CHRISTOPH
IPC: E05F15/00
Filed: 2021-06-07
Abstract: Die Erfindung betrifft ein System (2), umfassend eine Möbeltüreinheit (4) und ein in eine Einbaunische (6) einer Möbelumgebung (8) einbaubares Haushaltsgerät (10), wobei die Möbeltüreinheit (4) eine Möbeltür (12) und eine Möbeltürbewegungsvorrichtung (14) aufweist, und wobei die Einbaunische (6) mit dem darin eingebauten Haushaltsgerät (10) in einer Schließlage der Möbeltür (12) vollständig verdeckt ist und in mindestens einer Öffnungslage der Möbeltür (12) für eine Nutzung des Haushaltsgeräts (10) zugänglich ist. 
     Um ein System (2), umfassend eine Möbeltüreinheit (4) und ein in eine Einbaunische (6) einer Möbelumgebung (8) einbaubares Haushaltsgerät (10), sowie ein Verfahren zum Betrieb des Systems (2) zu verbessern, wird vorgeschlagen, dass die Möbeltürbewegungsvorrichtung (14) mindestens einen Möbeltürantrieb zur Bewegung der Möbeltür (12) in deren vorgenannte Lagen aufweist, wobei der Möbeltürantrieb mittels einer Steuerung des Haushaltsgeräts (10) automatisch ansteuerbar ist.
Patent EP-3913992-A1 (EP)
Inventor: JIANG DAN
IPC: H04W52/02
Filed: 2019-01-04
Abstract: An electronic device able to communicate using both a long-range and a short-range wireless communication technology. A transceiver of the electronic device switches its operation mode based on a power saving mode of the long-range wireless communication technology. In particular, the electronic device switches between a short-range mode and a long-range mode based on the power saving mode of the long-range communication technology.
Patent EP-3907224-A1 (EP)
Inventor: MCGONAGLE ALISON E
IPC: C07D413/06
Filed: 2015-12-17
Abstract: The present invention relates to compounds of formula I that function as inhibitors of PARG (Poly ADP-ribose glycohydrolase) enzyme activity:
     
wherein R 1a , R 1b , R 1c , R 1d , R 1e , W, X 1 , X 2 , X 3 , X 4 , X 5 , X 6 , X 7 , c are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which PARG activity is implicated.
Patent EP-4020067-A1 (EP)
Inventor: PARK JUNGHYUN
IPC: G02F1/017
Filed: 2021-06-23
Abstract: A light modulating device for modulating incident light in a given wavelength band is provided. The light modulating device may include: a first semiconductor layer; an active layer provided on the first semiconductor layer and having a multiple quantum well structure and a refractive index that is variable according to an electric field applied thereto, and a second semiconductor layer provided on the active layer and including a grating pattern in which a plurality of gratings extending in a first direction are repeatedly arranged in a second direction perpendicular to the first direction. The light modulating device may have high modulation efficiency owing to guided mode resonance by the grating pattern.
Patent EP-3970955-A1 (EP)
Inventor: PLUMMER STEVEN JOSEPH
IPC: B64C3/18
Filed: 2021-07-05
Abstract: A tool is configured to form a composite charge into a stringer having a net shape with at least one out-of-place feature. The out-of-plane feature is formed by a shim removably attached to the tool. A family of the shims may be used to form a range of out-of-plane features having varying characteristics.
Patent EP-4116219-A1 (EP)
Inventor: NEDELCU MICHAEL
IPC: C08L27/06
Filed: 2021-07-07
Abstract: Die Erfindung betrifft die Verwendung eines Polymergemisches zur Herstellung einer transparenten oder transluzenten, durchdrückbaren Deckelfolie (D) für eine Blisterpackung, wobei das PolymergemischA) eine erste Komponente K1 umfasst, welche ein cycloolefinisches Copolymer (COC) und/oder ein cycloolefinisches Polymer (COP) enthält; undB) eine zweite Komponente K2 umfasst, welche zur Hauptsache entweder ein Polypropylen (PP) oder ein Polyvinylchlorid (PVC) oder ein Polyethylen mit hoher Dichte (HDPE) oder Mischungen davon enthält,wobei das Gewichtsverhältnis zwischen der Komponente K1 und der Komponente K2 im Bereich von 1:5 bis 1:12 liegt.
Patent EP-4120362-A1 (EP)
Title: Power semiconductor device
Inventor: GUPTA GAURAV
IPC: H01L29/78
Filed: 2021-07-16
Abstract: In at least one embodiment, the power semiconductor device (1) comprises: 
- a semiconductor body (2) having a source region (21) of a first conductivity type and a well region (22) of a second conductivity type different from the first conductivity type, and the well region (22) comprises a channel region (220) starting directly at the source region (21), and 
- a gate insulator (4) directly between the semiconductor body (2) and a gate electrode (31), 
wherein the gate insulator (4) has a non-uniform gate dielectric constant profile along the channel region (220), such that a relative dielectric constant (ε OX ) of the gate insulator (4) is lowest in a first section (61) of the channel region (220) remote from the source region (21).
Patent EP-4123052-A1 (EP)
Inventor: CHOI DU-FHAN
IPC: C25B1/04
Filed: 2021-07-19
Abstract: Die Erfindung betrifft ein Verfahren zum Betrieb einer Elektrolyseanlage (100) zur Erzeugung von Wasserstoff und Sauerstoff als Produktgase, bei dem das Wasserstoff-Produktgas aus einem Elektrolyseur (1), welches auch Sauerstoff als Fremdgas enthält, einem nachgeschalteten Gas-Separator (3) zugeführt wird, wobei bei Überschreiten eines vorbestimmten Grenzwerts für die Sauerstoffkonzentration im Wasserstoff-Produktgas dem Gas-Separator (3) Wasserstoff mit einer geringen Sauerstoffkonzentration zugeführt wird, so dass die Sauerstoffkonzentration im Wasserstoff-Produktgas abgesenkt wird.Die Erfindung betrifft weiterhin eine entsprechende Elektrolyseanlage (100).
Patent EP-4122342-A1 (EP)
Inventor: SHULTZ WILLIAM
IPC: A41D27/10
Filed: 2021-07-22
Abstract: Exemplary embodiments contained herein include garments having biomechanical components including panels for influencing the wearer. Exemplary embodiments contained herein include garments having features for improving comfort of the wearer during use.
Patent EP-3973972-A1 (EP)
Inventor: RABOVSKY ALEXANDER B
IPC: A61K9/48
Filed: 2016-01-04
Abstract: This document provides dietary supplement compositions. For example, multi-supplement compositions having combinations of dietary supplement formulations useful for human or animal consumption are provided.
Patent EP-3926082-A1 (EP)
Inventor: PODHAJNY DANIEL A
IPC: D04B1/12
Filed: 2014-11-12
Abstract: An article of footwear including a full monofilament upper is described. The full monofilament upper incorporates a knitted component including a monofilament knit element. The monofilament knit element is formed by knitting with a monofilament strand. The monofilament knit element is formed of unitary knit construction with the remaining portions of the knitted component, including peripheral portions that are knit using a natural or synthetic twisted fiber yarn. An inlaid tensile element can extend through the knitted component, including portions of the monofilament knit element. The monofilament knit element may be knitted with a monofilament strand according to a variety of knit structures.
Patent EP-3936980-A1 (EP)
Inventor: STERN DEVON JAMES O'REILLEY
IPC: G06F3/01
Filed: 2019-08-30
Abstract: This document describes techniques and systems that enable input methods for mobile devices. A radar field (110) enables an electronic device (102) to accurately determine that a user's hand (112) is within a gesture zone (118) around the device. Further, the device can determine whether an application configured to receive input through radar-based gestures (radar gestures) is operating on the device. Using these techniques, the device can present a feedback indicator (120) on a display (114) when the user's hand is within a gesture zone around the device. The feedback indicator alerts the user that the user's hand is close enough to the device to make specific radar gestures. This allows the device to provide the user with feedback, which can educate the user about the device's capabilities and allow the user to take advantage of additional functionality and features provided by the availability of the radar gestures.
Patent EP-3928953-A1 (EP)
Title: Blasformmaschine mit wechselroboter und greifeinrichtung und verfahren zu deren betrieb
Inventor: FINGER DIETER
IPC: B29C49/48
Filed: 2014-11-26
Abstract: Eine Vorrichtung zum Umformen von Kunstoffvorformlingen (10) zu Kunststoffbehältnissen (20) mit einer Transporteinrichtung (2), welche die Kunststoffvorformlinge (10) entlang eines vorgegebenen Transportpfads transportiert, wobei die Transporteinrichtung (2) einen beweglichen und zumindest mittelbar an einem stationären Basisträger (6) angeordneten Stationsträger (12) aufweist, an dem eine Vielzahl von Umformungsstationen (8) angeordnet ist, wobei diese Umformungsstationen (8) jeweils Blasformeinrichtungen (14) aufweisen, welche jeweils Hohlräume ausbilden, innerhalb derer die Kunststoffvorformlinge (10) zu den Kunststoffbehältnissen umformbar sind und diese Blasformeinrichtungen jeweils an Blasformträgern (16) angeordnet sind. Erfindungsgemäß weist die Vorrichtung (1) eine Wechseleinrichtung (40) auf, welche geeignet und dazu bestimmt ist, zumindest die Blasformeinrichtungen von deren Blasformträgern (16) zu entfernen und/oder Blasformeinrichtungen an den Blasformträgern (16) anzuordnen, wobei diese Wechseleinrichtung (40) eine Greifeinrichtung (52) zum Greifen der Blasformeinrichtung (14) aufweist wobei diese Greifeinrichtung (52) in wenigstens zwei unterschiedliche Richtungen beweglich und um wenigstens drei unterschiedliche Schwenkachsen (A1, A2...A6) schwenkbar ist.
Patent EP-3954373-A1 (EP)
Inventor: GOLDENBERG DAVID M
IPC: A61K31/166
Filed: 2015-10-05
Abstract: The present invention is related to an antibody-drug conjugate (ADC) for use in a method for neoadjuvant treatment of cancer comprising: 
     a) administering the antibody-drug conjugate (ADC) comprising an antibody moiety conjugated to a drug, to a subject with cancer, wherein the antibody moiety is an anti-Trop-2 hRS7 antibody and the drug is SN-38; and 
b) treating the subject with a standard anti-cancer therapy selected from the group consisting of a checkpoint inhibitor therapy and chemotherapy, and wherein the ADC is administered before the standard anti-cancer therapy.
Patent EP-3968431-A1 (EP)
Title: Procédé et dispositif de gestion du comportement thermique d'une batterie
Inventor: GUILLET NICOLAS
IPC: H01M10/42
Filed: 2021-09-13
Abstract: L'invention concerne un procédé de gestion du comportement thermique d'une batterie (BATT), ledit procédé consistant à :- Employer un modèle thermique (MOD_TH) de la batterie, configuré pour estimer, à chaque instant, une puissance thermique (W<sub>th</sub>) générée par la batterie en fonction d'une puissance électrique (W<sub>elect</sub>) mesurée traversant la batterie, ledit modèle thermique comportant une loi à la charge et une loi à la décharge, chaque loi étant basée sur l'état de charge de la batterie (SoC) et sur sa température (T) et intégrant la constante de temps (τ) de la batterie,- Contrôler (CTRL) la puissance thermique (W<sub>th</sub>) générée par la batterie.
Patent EP-3978836-A1 (EP)
Title: Kühlkreislauf
Inventor: LANGEBACH ROBIN
IPC: F25B6/04
Filed: 2021-09-16
Abstract: Es wird ein Kühlkreislauf (100) vorgeschlagen. der Kühlkreislauf (100) umfasst einen Kältemittelverdichter (102) mit mindestens einem Arbeitsraum (104), einen Wärmeübertrager (106) mit einem Fluidsammelraum (108), wobei der Fluidsammelraum (108) zum Bilden eines Kältemittelvorrats aus Kältemittel ausgebildet ist, und eine Zufuhreinheit (114). Die Zufuhreinheit (114) ist mit dem Fluidsammelraum (108) und dem Kältemittelverdichter (102) verbunden. Die Zufuhreinheit (114) weist eine Hochdruckpumpe (116) und einen Injektor (118) auf. Die Zufuhreinheit (114) ist zum Zuführen von Kältemittel aus dem Kältemittelvorrat zu dem Arbeitsraum (104) mittels des Injektors (118) bei einem Druck oberhalb eines Abgabedrucks des Kältemittelverdichters (102) ausgebildet.
Patent EP-3971870-A1 (EP)
Title: Advanced haptics in touchscreen avionics lower level device simulators
Inventor: HEYD PAUL
IPC: G06F3/041
Filed: 2021-09-17
Abstract: An avionics lower level device (LLD) simulator may include at least one touchscreen display device (120). The at least one touchscreen display device may include a display stack assembly including at least one touchscreen sensor (202) and a display (206) and at least one advanced haptic feedback component (218) positioned proximate to the display stack assembly. The at least one touchscreen display device may be configured to display at least one GUI or GUI icon, the at least one GUI or GUI icon related to an operation of an aircraft, may be configured to provide at least one advanced haptic feedback response following an interaction with the at least one GUI or GUI icon displayed on the at least one touchscreen display device, and may be configured to mimic a physical response observed following an operation of a mechanical component installed within a cockpit of the aircraft.
Patent EP-3985073-A1 (EP)
Title: Opacifying clusters for use in paint compositions
Inventor: REUTER JAMES M
IPC: C09D7/61
Filed: 2017-03-16
Abstract: An opacifying cluster which may be added to a coating composition to provide a coating composition with low gloss and a high level of opacity. The opacifying cluster can include a polymeric latex binder coalescing cluster components into a generally homogeneous particle.The cluster components may include discrete polymeric particles each defining a closed void volume therein, a plurality of inorganic pigment particles, and a plurality of extender pigment particles. The clusters may also include a porosity of the polymeric latex binder thereof defining a binder void volume. Also provided is a paint product including such a pigment cluster.
Patent EP-4154797-A1 (EP)
Title: Verfahren zum bestimmen einer diagnostisch relevanten schnittebene
Inventor: DR GIESE DANIEL
IPC: A61B5/055
Filed: 2021-09-22
Abstract: Ein computerimplementiertes Verfahren zum Bestimmen einer Ausrichtung wenigstens einer diagnostisch relevanten Schnittebene für eine Herzbildgebung in einem dreidimensionalen Magnet-Resonanz-Tomographie Bilddatensatz umfasst einen Verfahrensschritt eines Bereitstellens (PROV-1) des dreidimensionalen Bilddatensatzes. Das Verfahren umfasst außerdem einen Verfahrensschritt eines Anwendens (APP) einer trainierten Funktion auf den dreidimensionalen Bilddatensatz. Dabei wird eine Position wenigstens einer Landmarke bestimmt wird. Das Verfahren umfasst außerdem einen Verfahrensschritt eines Bestimmens (DET) der Ausrichtung der wenigstens einen diagnostisch relevanten Schnittebene in Abhängigkeit der wenigstens einen Landmarke. Das Verfahren umfasst außerdem einen Verfahrensschritt eines Bereitstellens (PROV-2) der Ausrichtung der wenigstens einen diagnostisch relevanten Schnittebene.
Patent EP-4156183-A1 (EP)
Title: Audio device with a plurality of attenuators
Inventor: ADESOKAN BOLAJI JAMES
IPC: G10L21/0216
Filed: 2021-09-28
Abstract: An audio device comprising an interface, memory, and a processor is disclosed, wherein the processor is configured to: obtain a first microphone input signal and a second microphone input signal; process the first microphone input signal and the second microphone input signal for provision of an output audio signal; and output the output audio signal; wherein to process the first microphone input signal and the second microphone input signal comprises to: determine a primary gain with a primary attenuator based on one or more features associated with the first microphone input signal and the second microphone input signal; determine a secondary gain with a secondary attenuator based on one or more features associated with the first microphone input signal and the second microphone input signal; determine a noise suppression scheme based on the primary gain and the secondary gain; and apply the noise suppression scheme to a first beamforming output signal for provision of the output audio signal.
Patent EP-4164268-A1 (EP)
Inventor: BOTT ANDREW
IPC: H04W12/0431
Filed: 2021-10-07
Abstract: The invention relates to a provisioning control apparatus (140a) configured to be coupled to a provisioning equipment server (160), wherein the provisioning equipment server (160) is electrically connectable with one or more electronic devices (170) for provisioning the electronic devices (170) with security sensitive provisioning data (150). The provisioning control apparatus (140a) comprises a processor (141a) configured to generate a group context for sharing the group context with a first further provisioning control apparatus (140b) for creating a group of provisioning control apparatuses (140a,b). The group context comprises a group private key, a certificate for the group private key and a group encryption key used for encryption and/or decryption and the first further provisioning control apparatus (140b) is configured to be coupled to the provisioning equipment server (160). The processor (141a) is further configured to generate the security sensitive provisioning data (150) based on the group context. The provisioning control apparatus (140a) further comprises a communication interface (143a) configured to provide the security sensitive provisioning data (150) to the provisioning equipment server (160).
Patent EP-4074814-A1 (EP)
Inventor: MI HSIN WU
IPC: C12M1/32
Filed: 2021-11-02
Abstract: A cell and medicament dispensing device for drug screening. The device has a base (10), a transfer plate serving mechanism (21), a transfer plate positioning mechanism (30), an injection mechanism (40), a cell culture plate positioning mechanism (60), and a dispensing mechanism (80). The transfer plate serving mechanism (21) moves a transfer plate (92) to the transfer plate positioning mechanism (30). The injection mechanism (40) injects cells and medicaments into recesses in the transfer plate (92). The dispensing mechanism (80) moves between the transfer plate (92) and the cell culture plate (94) to dispense the cells or medicaments from the transfer plate (92) to a cell culture plate (94) fixed in the cell culture plate positioning mechanism (60). As a result, drug screening is automated to reduce labor and improve quality.