baber/WOPTO huggingface dataset:
Patent WO-2020181254-A1 (WO)
Title: Sequence-graph based tool for determining variation in short tandem repeat regions
Inventor: DOLZHENKO EGOR
IPC: G16B20/00
Filed: 2020-03-06
Abstract: The disclosed embodiments concern methods, apparatus, systems and computer program products for genotyping repeat sequences such as medically significant short tandem repeats (STRs). The methods involve aligning reads to a repeat sequence represented by a sequence graph, and using the aligned reads to genotype the repeat sequence. The sequence graph is a directed graph each including at least one self-loop representing a repeat sub-sequence. In some implementations, the reads are paired end reads, and both mates of each read pair may be used to genotype the repeat sequences. Some implementations can be used to determine degenerate codon repeats. Some implementations can be used to genotype repeat sequences each including two or more repeat sub-sequences. Some implementations can be used to genotype nucleic acid sequences each including at least one repeat sub-sequence and another genetic variant such as an insertion, deletion, or substitution.
Patent WO-2020214325-A1 (WO)
Title: Vehicle sensor data acquisition and distribution
Inventor: NADERI ALIZADEH MOHAMMADHOSSEIN
IPC: H04W4/38
Filed: 2020-03-19
Abstract: Various aspects enable sensor data to be obtained from vehicles. Various aspects may enable data gathered by sensors of vehicles to be obtained by a data agency server and made available to third party client devices. In various aspects, a data agency server may direct a vehicle to drive from the vehicle's current location to a different specific location to gather a type of data. In some aspects, the type of data may be peripheral data that is not associated with driving operations of a vehicle. In some aspects, a data agency server may indicate one or more attributes of collection for the vehicle to utilize in gathering data. In some aspects, an attribute of collection may set a condition of the vehicle and/or the sensor utilized in gathering data. In some embodiments, vehicle owners/operators may be compensated for their vehicles being utilized to obtain data.
Patent WO-2020191254-A1 (WO)
Title: Tissu à isolation thermique
Inventor: OHANIANS RAFFI
IPC: D03D25/00
Filed: 2020-03-20
Abstract: L'invention concerne un tissu pour une paire de jeans. Le tissu a une pluralité de fils de chaîne et une pluralité de fils de trame. La pluralité de fils de chaîne comprennent un fil de chaîne de jeans, tel que le coton, disposé à côté d'un fil de chaîne isolant, tel que la laine, dans une série répétitive. La pluralité de fils de trame comprennent une pluralité de fils de trame de jeans disposés les uns à côté des autres dans une série répétitive. La pluralité de fils de chaîne et de fils de trame sont entrelacés perpendiculairement dans une armure sergée définissant un côté avant opposé à un côté arrière. À partir du côté avant du tissu, chaque fil de chaîne de jeans est tissé sur trois fils de trame de jeans et sous un fil de trame de jeans dans une série répétitive. À partir du côté avant du tissu, chaque fil de chaîne isolant est tissé sous trois fils de trame de jeans et sur un fil de trame de jeans dans une série répétitive.
Patent WO-2020219203-A1 (WO)
Title: Insights into performance of a bot system
Inventor: SUBRAMANIAM SRIKANT
IPC: G06F11/32
Filed: 2020-03-25
Abstract: The present disclosure relates generally to techniques for analyzing and improving a bot system, and more particularly to an analytic system integrated with a bot system for monitoring, analyzing, visualizing, diagnosing, and improving the performance of the bot system. For example, an analytic system is integrated with a bot system for monitoring, analyzing, visualizing, and improving the performance of the bot system. The analytic system monitors events occurred in conversations between end users and the bot system, aggregates and analyzes the collected events, and provides information regarding the conversations graphically on a graphic user interface as insights reports at different generalization levels. The insights reports offer developer-oriented analytics to pinpoint issues with skills so a user can address them before they cause problems. The insights let a user track conversation trends over time, identify execution paths, determine the accuracy of their intent resolutions, and access entire conversation transcripts.
Patent WO-2020205478-A1 (WO)
Inventor: TURNBULL PHILIP
IPC: C07D403/12
Filed: 2020-03-27
Abstract: Compounds are provided having the structure of Formula (I) or a pharmaceutically acceptable salt, homolog, hydrate or solvate thereof, wherein R a  is as defined herein. Such compounds serve as modulators of the sphingosine-1-phosphate receptor, and have utility for treatment of a malcondition for which activation of this receptor is medically indicated.
Patent WO-2020205830-A1 (WO)
Inventor: SAUNDERS FRANCIS
IPC: A61B5/08
Filed: 2020-03-31
Abstract: La présente invention concerne des procédés et des systèmes qui analysent un ou plusieurs analytes dans un fluide, tel que l'haleine, émis par un utilisateur. Les procédés et les systèmes peuvent détecter un ou plusieurs analytes dans l'haleine d'un utilisateur pour fournir des alertes en réponse à des écarts de médicaments pris par un utilisateur, vérifier un ou plusieurs médicaments pris par un utilisateur, gérer un régime médicamenteux d'un utilisateur, et diverses autres fonctions décrites dans la description.
Patent WO-2021118626-A1 (WO)
Inventor: MIJTS BENJAMIN
IPC: C12N15/52
Filed: 2020-04-01
Abstract: The present disclosure provides new RNA-guided nucleases for making rational, direct edits to nucleic acids in live cells. The present disclosure provides mined MAD-series nucleases (e.g., RNA-guided nucleases or RGNs) with varied PAM preferences, and/or varied activity in mammalian cells. In some aspects, the MAD-series system components are delivered as sequences to be transcribed (in the case of the gRNA components) and transcribed and translated (in the case of the MAD-series nuclease), and in some aspects, the coding sequence for the MAD-series nuclease and the gRNA component sequences are on the same vector.
Patent WO-2020231859-A1 (WO)
Title: Clostridioides difficile tcdb variants, vaccines and methods of use
Inventor: BALLARD JIMMY
IPC: A61K39/08
Filed: 2020-05-08
Abstract: An immunogenic composition comprising a deletion mutant of a  Clostridioides difficile  TcdB toxin (such as TcdB2 or TcdB1) that lacks residues at least from amino acid residue 1769 to amino acid residue 1787 of a wild-type TcdB amino acid sequence or of a protein having high identity thereto, a vaccine comprising the immunogenic composition, a method of stimulating an immune response, a nucleic acid which encodes the amino acid sequence of the deletion mutant, a vector encoding the nucleic acid, and a host cell comprising the vector.
Patent WO-2020231968-A1 (WO)
Inventor: CHEN MONICA
IPC: A61K31/439
Filed: 2020-05-12
Abstract: La présente invention concerne des procédés et des produits destinés au conditionnement et à l'expédition de cellules thérapeutiques pour une thérapie cellulaire.
Patent WO-2020232179-A1 (WO)
Title: Commande de réseau de capteurs ultrasonores pour faciliter des dispositifs de protection d'écran
Inventor: LU YIPENG
IPC: G06K9/00
Filed: 2020-05-13
Abstract: La présente invention concerne des techniques permettant de faire fonctionner un réseau de capteurs ultrasonores, le réseau de capteurs ultrasonores étant disposé sous une platine, lesdites techniques consistant: à réaliser une détermination pour savoir s'il faut, ou non, étalonner à nouveau le réseau de capteurs ultrasonores sur la base du fait qu'un premier dispositif de protection d'écran disposé au-dessus de la platine a été retiré ou remplacé par un second dispositif de protection d'écran ; et à étalonner à nouveau le réseau de capteurs ultrasonores, lorsque la détermination est d'étalonner à nouveau le réseau de capteurs ultrasonores. Dans certains cas, les techniques consistent à inviter un utilisateur à indiquer si le dispositif de protection d'écran a été, ou non, changé ou retiré, et à étalonner à nouveau le réseau de capteurs ultrasonores uniquement après la confirmation de l'utilisateur.
Patent WO-2021006963-A1 (WO)
Title: Porte-article stratifié et ébauche associée
Inventor: WALLING BRADFORD J
IPC: B65D71/42
Filed: 2020-05-22
Abstract: La présente invention concerne, selon certains aspects, un porte-article (90) destiné à l'emballage d'un ou plusieurs articles B, une ébauche (10) destinée à former le porte-article et un procédé de formation du porte-article. Selon un aspect, l'invention concerne un porte-article à prise supérieure destiné à emballer au moins un article. Le porte-article comprend un panneau principal (12) comprenant au moins un dispositif à prise supérieure ayant une ouverture de réception supérieure. Le panneau principal comprend une structure stratifiée composée d'au moins deux couches (L1, L2) d'un substrat (50) liées uniformément l'une à l'autre.
Patent WO-2020243343-A1 (WO)
Inventor: MCBRIDE MICHELLE
IPC: A23C21/10
Filed: 2020-05-28
Abstract: Une boisson d'hydratation de longue conservation peut être préparée sur la base d'un perméat laitier. Le perméat laitier peut être sensiblement exempt de lactose et peut avoir une concentration en ions sodium d'environ 10-30 mMol/L, une concentration en chlorure d'environ 20-40 mMol/L, et un agent d'acidification. La boisson peut avoir un pH inférieur à 3,60.
Patent WO-2020247325-A1 (WO)
Title: Inflow control including fluid separation features
Inventor: Koli Jai Kishan
IPC: E21B43/12
Filed: 2020-06-02
Abstract: An apparatus for separating fluids and controlling flow of production fluid includes a support structure configured including a fluid conduit and a tubular assembly disposed at the support structure. The tubular assembly includes an outer tube defining a flow path and having an outer tube inlet in fluid communication with the production fluid, and at least one inner tube disposed eccentrically within the outer tube. The support structure and/or the tubular assembly is configured to cause a centrifugal force on the production fluid that at least partially separates the production fluid into a first fluid portion having a higher concentration of high density fluid than an initial concentration, and a second fluid portion having a higher concentration of the low density fluid than the initial concentration of the low density fluid. One or more inner tubes have an inner tube outlet in fluid communication with the fluid conduit.
Patent WO-2020252140-A1 (WO)
Inventor: GORNY THOMAS
IPC: H04L12/18
Filed: 2020-06-11
Abstract: A system and method are disclosed for generating a chat space for two or more communication devices using a computer coupled with a database and comprising a processor and memory. The computer generates a chat space and transmits requests to join the chat space to the two or more communication devices. The computer stores in memory identification information for each of the two or more communication devices and one or more public chat messages transmitted between the two or more communication devices. The computer monitors for one or more requests, transmitted from one of the two or more communication devices to the computer, to generate a private thread. In response to one or more requests, the computer generates a private thread, and stores in the computer memory one or more private thread messages transmitted between two or more communication devices in the private thread.
Patent WO-2021003067-A1 (WO)
Inventor: VILLETTE THIBAULT
IPC: B29C64/153
Filed: 2020-06-26
Abstract: A system (100) and method for optimizing an additive manufacturing process in which a reinforcement material (117) is randomly introduced to a fabrication bed (103). An image of the fabrication bed is captured. The image is analyzed by code in a computer (132) to identify the actual arrangement of the randomly deposited reinforcement material relative to the object (A) being manufactured. Based on the image data showing the reinforcement material, a toolpath is dynamically determined that incorporates the random reinforcement material. Accordingly, the toolpath incorporates the reinforcement material into the structure of the object, which can result in a reduction of the total amount of raw material is fused to create the object being manufactured.
Patent WO-2021016393-A1 (WO)
Title: Biocompatible sensor device and method for detecting environmental stimuli therewith
Inventor: TSENG PETER
IPC: G01N33/487
Filed: 2020-07-22
Abstract: A sensor device includes an inner hydrogel layer, a first planar metallic structure adjacent to a first surface of the inner hydrogel layer, and a second planar metallic structure adjacent to a second surface of the inner hydrogel layer opposite to the first surface. A sensor device further includes an encasing layer at least partially enclosing at least one of the inner hydrogel layer, the first planar metallic structure, and the second planar metallic structure. A method for use of the sensor device includes receiving at least one environmental stimulus, modifying a capacitance of a hydrogel in response to the received environmental stimulus, and generating an electrical stimulus response based on the modified capacitance. The method further includes modifying the capacitance of the hydrogel by modifying a resonant frequency of the hydrogel. The method further includes modifying the signal magnitude response of the hydrogel by shifting the signal magnitude response relative to the resonant frequency of the hydrogel. A method for manufacturing the sensor device includes forming a plurality of planar metallic structures, forming an inner hydrogel, and affixing the inner hydrogel between the planar metallic structures.
Patent WO-2021022095-A1 (WO)
Inventor: SCHAFER DAVID
IPC: G01D4/00
Filed: 2020-07-30
Abstract: A broadband access system, comprising a broadband access hub device (hub device) and broadband access premise devices (premise devices) wirelessly coupled the hub device to provide broadband services to multiple user equipment (UEs), is described. The hub device may access broadband services on a fiber optic broadband network and wirelessly provide access to the broadband services to the premise devices. The premise device may wirelessly communicate with the hub device and communicate with user equipment (UEs) for providing access to the broadband services through the hub device. The premise device may be attached to an electric utility meter, and a power interface module of the premise device may supply electrical power to the premise device from the electric utility meter. Additionally, the first communication module of the premise device may be external to the premise device and be mounted remotely from the premise device.
Patent WO-2021035192-A1 (WO)
Title: Lidar adapter for use with lidar chip
Inventor: FENG DAZENG
IPC: G01S17/42
Filed: 2020-08-21
Abstract: A LIDAR system includes a LIDAR chip that outputs a LIDAR output signal; a LIDAR adapter that receives the LIDAR output signal from the LIDAR chip and also outputs the LIDAR output signal from the system and toward a sample region in a field of view. The LIDAR adapter also receives a LIDAR return signal that includes light from the LIDAR output signal after the LIDAR output signal is reflected by an object located in the sample region. The LIDAR output signal and the LIDAR return signal travel the same optical pathway between the LIDAR adapter and the object. The LIDAR adapter is also configured to output a LIDAR input signal that is received by the LIDAR chip and includes or consists of light from the LIDAR return signal. The LIDAR input signal and the LIDAR output signal travel different optical pathways between the LIDAR adapter and the LIDAR chip.
Patent WO-2022046053-A1 (WO)
Inventor: ZHOU RENBIN
IPC: G06F3/03
Filed: 2020-08-27
Abstract: Endoscope commandé par un système robotique chirurgical. Une entrée d'utilisateur ayant six degrés de liberté est associée à la commande d'un endoscope par un bras robotique ayant un nombre de degrés de liberté inférieur. Par exemple, des dispositifs d'interface utilisateur non attachés commandent le mouvement d'un endoscope à travers une série de projections d'une commande d'utilisateur, à un mouvement d'endoscope, et à un mouvement d'articulation du bras robotique. La projection d'une commande d'utilisateur à un mouvement d'endoscope peut projeter un mouvement angulaire singulier à partir de trois mouvements angulaires des dispositifs d'interface utilisateur. La projection peut prendre en compte le centre de mouvement à distance et/ou une orientation angulaire de la vue de l'endoscope par rapport à un arbre de l'endoscope.
Patent WO-2021046148-A1 (WO)
Title: Placket and collar stabilization
Inventor: KRIGER JOSHUA
IPC: A41B3/06
Filed: 2020-09-03
Abstract: The present invention relates to the stabilization of a shirt or blouse placket and/or shirt collar when the shirt is worn without a tie, without upper fastening means near the wearer's neck or collar region, or and with the upper fastening means near the wearer's neck or collar region, such as one or more buttons, unfastened.
Patent WO-2021046353-A1 (WO)
Title: In-manifest update event
Inventor: SODAGAR IRAJ
IPC: G06F15/16
Filed: 2020-09-04
Abstract: There is included a method and apparatus comprising computer code configured to cause a processor or processors to perform publishing media presentation description data comprising main live program data, and signaling a client device about ad data and in-manifest data where the ad data instructs the client device of an initial end time at which to end a display of an ad by switching a display at the client device from the ad to the main live program data and where the in-manifest data instructs the client device to determine, during a streaming of the ad to the client device, an updated end time, prior to the end time, at which to end the streaming of the ad by switching the streaming at the client device from the ad to the main live program data.
Patent WO-2021046441-A1 (WO)
Title: Electrically conductive hydrogels usable as lead extensions, apparatus for delivery of a hydrogel into the vasculasture, and methods of treating ventricular arrhythmia with electrically conductive hydrogels injected in the venous system
Inventor: COSSGRIFF-HERNANDEZ ELIZABETH
IPC: A61M25/00
Filed: 2020-09-04
Abstract: A conductive hydrogel precursor solution cures after injection into the vasculature of the myocardium. The vasculature acts as a mold for the hydrogel and allows for a pacing signal to be conducted across the myocardium and not at a single point like traditional pacing leads. The catheter-based delivery can accurately place the hydrogels into the myocardial veins and can fill the venous tributaries. In situ crosslinking of the hydrogel precursor solution is achieved through several mechanisms, such as redox initiation by mixing a reducing reagent and oxidizing agent after injection. Conductivity is achieved by doping in conductive polymers or other conductive elements such as ionic species, metallic nanoparticles, or graphene nanoplatelets. To ensure long-term conductivity, hydrogel macromers may be synthesized without hydrolytically labile groups such as esters, and the conductive elements may be conjugated directly to the hydrogel matrix.
Patent WO-2021067097-A1 (WO)
Inventor: ZHOU YAN
IPC: H04B7/08
Filed: 2020-09-23
Abstract: A UE determines a default beam for a physical downlink shared channel (PDSCH) that is independent of a beam for a physical downlink control channel (PDCCH). The default PDSCH beam may be determined based on information received in a medium access control-control element (MAC-CE), or a radio resource control (RRC) message, a downlink control information (DCI). The default PDSCH beam may be determined based on at least one active transmission configuration indication (TCI) state for the PDSCH.
Patent WO-2021067127-A1 (WO)
Inventor: BRAHIM SEAN IMTIAZ
IPC: B82Y99/00
Filed: 2020-09-25
Abstract: The present invention relates to a lithium ion battery cell having a cathode comprising an active material and about 1-5% by weight of single wall carbon nanotubes (SWCNT) as a conductive additive, wherein the SWCNT has an inorganic impurity content of less than 5% by weight. The LiB cathode of the present invention improves performance characteristics such as higher capacity, lower cell resistance, and retention of greater capacity with cycling of the fully assembled cell, in comparison to LiB cells using only conventional conductive carbon additive in the cathode.
Patent WO-2021067434-A1 (WO)
Inventor: HOLT FREDERICK
IPC: H04W12/08
Filed: 2020-09-30
Abstract: A method according to one embodiment includes receiving, by a gateway device and from an access control device, credential data received by the access control device from a mobile device in response to presentation of the mobile device to the access control device, comparing the credential data to a gateway credential list stored in a memory of the gateway device, the gateway credential list identifying a plurality of credentials associated with the gateway device, and each credential of the plurality of credentials associated with a unique credential index, transmitting, to a server, the unique credential index associated with the credential data in response to determining that the credential data matches a corresponding credential in the gateway credential list, and receiving, from the server, an access control decision associated with the credential data in response to transmitting the unique credential index.
Patent WO-2021067496-A1 (WO)
Title: Système de casque d'absorption et de dispersion de chocs
Inventor: REYNOLDS DAVID
IPC: A42B3/06
Filed: 2020-09-30
Abstract: La présente invention concerne d'une manière générale des systèmes, des dispositifs et des procédés pour atténuer la propagation d'énergie à travers des casques pendant une collision, réduisant ainsi le risque de lésion cérébrale d'une lésion cérébrale traumatique. Par exemple, un système d'absorption de chocs peut être utilisé pour augmenter l'absorption d'énergie de forces se propageant à travers un casque. Dans une configuration particulière, le système d'absorption comprend une coque externe, une pluralité d'éléments d'absorption de chocs, un ou plusieurs revêtements et/ou une couche de mousse pour atténuer les forces résultantes d'un choc qui atteint le cerveau d'un utilisateur.
Patent WO-2021071919-A1 (WO)
Title: Hck as a therapeutic target in myd88 mutated diseases
Inventor: TREON STEVEN P
IPC: A61K31/496
Filed: 2020-10-07
Abstract: The present disclosure provides compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, and prodrugs thereof. The provided compounds may be kinase (e.g., HCK, BTK, LYN, BLK, FRK) inhibitors. Also provided are pharmaceutical compositions and kits including the provided compounds. Further provided are methods of using the provided compounds, pharmaceutical compositions, and kits (e.g., for treating diseases (e.g., proliferative diseases) in a subject in need thereof).
Patent WO-2021080772-A1 (WO)
Title: Aqueous composition of organic polymeric microspheres, binder particles, and ion exchange resin
Inventor: BOHLING JAMES C
IPC: C09D5/02
Filed: 2020-10-07
Abstract: The present invention relates to a composition comprising an aqueous dispersion of a) polymer particles having a z- average particle size in the range of from 50 nm to 500 nm; b) anion exchange resin particles having a D50 median particle size in the range of from 0.1 μm to 50 μm; and c) polymeric organic microspheres having a D50 median particle size in the range of from 1 μm to 20 μm, wherein the weight-to-weight ratio of polymer particles to microspheres is in the range of from 0.5:1 to 20:1. The composition of the present invention is useful for paint compositions that form matte finishes with an excellent balance of stain blocking and stain removal properties.