baber/WOPTO huggingface dataset:
Patent DE-69535673-D1 (DE)
Inventor: SPRUCE BARBARA ANN
IPC: A61K38/22
Filed: 1995-08-30
Granted: 2008-02-07
Abstract: PCT No. PCT/GB95/02037 Sec. 371 Date Apr. 28, 1997 Sec. 102(e) Date Apr. 28, 1997 PCT Filed Aug. 30, 1995 PCT Pub. No. WO96/06863 PCT Pub. Date Mar. 7, 1996Agents which modulate pathways of apoptotic induction or repression in which products of opioid peptide precursors genes participate, useful as inducers of apoptosis in cells and in tumor cells in particular, are disclosed. Methods of treatment employing such agents and pharmaceutical compositions containing them are also described.
Patent DE-69606562-D1 (DE)
Inventor: HEILIGERS HERMANUS
IPC: B65D85/86
Filed: 1996-11-20
Granted: 2000-03-09
Abstract: This invention relates to the use of a linear dialkyl peroxide having an hexyne or an hexene backbone, for producing a controlled rheology polypropylene heterophasic copolymer of melt index Ml2 larger than 15 g/10 min, having simultaneously a very high impact resistance and a high flexural modulus. <IMAGE>
Patent DE-69607850-D1 (DE)
Inventor: ROQUETTE MICHEL
IPC: C03C17/02
Filed: 1996-12-20
Granted: 2000-05-25
Abstract: A glass container incorporates a decorative effect on its outer surface to give it an aesthetic appearance and/or to identify the producer. This decorative effect is indelible and made up of fine individual particles of enamel each melted in place on the surface layer of the glass thus creating, by their number, colour and disposition, the particular discontinuous visual and tactile impression of a patina and/or an old layer of dust. The method used to apply this decorative finish to a glass container is also claimed.
Patent DE-69612859-D1 (DE)
Inventor: REILLY M
IPC: B65B3/00
Filed: 1996-08-20
Granted: 2001-06-21
Abstract: This invention relates to a process for manufacturing prefilled syringes where at least one of the syringe components is manufactured in at least a class 100 environment. The process includes the steps of manufacturing syringe components, such as the barrel and plunger substrate, within at least a class 100 and MCB-3 environment; manufacturing syringe components, such as the plunger cover and tip seal in an environment less clean than a class 100 environment; decontaminating the plunger cover and tip seal; lubricating at least one of the barrel, plunger substrate, plunger cover and tip seal; assembling the barrel and tip seal to form a barrel/tip seal combination; assembling the plunger cover and plunger substrate to form a plunger; filling the barrel/tip seal combination with a predetermined amount of fluid; and final assembling of the prefilled syringe by inserting the plunger into the barrel/tip seal combination. When the syringe components are manufactured at different locations, each component is tripled-bagged to maintain the component substantially free from contaminants, and transported to an assembly site where the components are unpackaged and assembled into the barrel/tip seal combination and plunger. When filling and final assembly of the barrel/tip seal combination takes place at a location separate from its assembly site, the barrel/tip seal combination is tripled-bagged to maintain it substantially free from contaminants, and transported to a filling and final assembling site for filling and final assembling into a prefilled syringe.
Patent DE-69621187-D1 (DE)
Inventor: ROTHGANGL EHRHARD
IPC: E05F15/00
Filed: 1996-05-31
Granted: 2002-06-20
Abstract: The winch consists of a housing containing a drum with a wound cable, fixed to a frame and operated by an endless screw coupled to a second screw attached to a tilting stirrup actuated by a lever engaging with the endless screw wheel and disengaged by a lever and spring mechanism. The disengagement mechanism comprises a two-arm lever (19) with manual and pneumatic operation, and with its axis of rotation (18) located in the space between two parallel planes lying perpendicular to the winch locking plane. One plane passes through the axis of rotation of the endless screw wheel, and the other through the tilting axis of the stirrup. The lever's axis is preferably identical with the stirrup's tilting axis and, in a variant, the disengagement mechanism can comprise a one-arm lever which is operated electromagnetically.
Patent DE-69623961-D1 (DE)
Inventor: BIGG DENNIS
IPC: C07D313/00
Filed: 1996-06-21
Granted: 2002-10-31
Abstract: Camptothecin analogues where the camptothecin hydroxy lactone is: (i) a  beta -hydroxy lactone; or (ii) the corresp.  beta -hydroxy acid resulting from ring-opening of the aforementioned lactone; or a (iii) deriv. of the  beta -hydroxy acid in (ii) or its one of its salts. Also claimed are new industrial prods. of formula (M) and (A). R1 = lower alkyl, lower alkenyl, lower alkynyl, halo(lower alkyl), lower alkoxy(lower alkyl) or lower alkylthio(lower alkyl); R20 = H or halo; R22 = F, Cl, or lower alkoxy; R23 = prim. hydroxy-protecting gp.; and R18, R19 = H, halo, lower alkyl, lower alkoxy or OH.
Patent DE-69701843-D1 (DE)
Inventor: SANTANIELLO MOSE
IPC: C07C69/02
Filed: 1997-10-03
Granted: 2000-06-08
Abstract: An improved process for producing valproic acid from ethyl acetoacetate is disclosed wherein both the dialkylation of ethylacetoacetate with propyl bromide and the conversion of the dialkylester thus obtained to the corresponding salt take place in a single step, in the presence of a phase-transfer catalyst, in a hydroalcoholic environment, and the salt is converted to valproic acid at pH 1-3.
Patent DE-69708797-D1 (DE)
Inventor: PILE BRIAN FRANK
IPC: A61G7/057
Filed: 1997-09-05
Granted: 2002-01-17
Abstract: A mattress cover, for use on an air inflatable mattress which reduces the risk of bed sores in long term patients. The cover has a top sheet (31) and side sheets (5) attached to opposite edges of the top sheet. The length of the top sheet (3), in a laid-flat state, is greater than the length of the side sheets (5) attached to the top sheet. This allows the cover to closely follow the undulating nature of the inflatable cells of the mattress, and zero pressure may be achieved. The cover may also comprise end sheets (25), an outer skirt (9), and a base portion (7). The present invention also provides a method of making cover, which comprises the step of stretching the side portions, while the top sheet is in a substantially unstretched condition, and then joining the side sheets in their stretched condition to the top sheet. <IMAGE>
Patent DE-69716593-D1 (DE)
Inventor: GARCIA-NAVARRO LOPEZ DE HIERRO
IPC: C07C62/32
Filed: 1997-07-24
Granted: 2002-11-28
Abstract: Process for the recovery of oleanolic and maslinic acids contained in the subproducts resulting from the milling and processing of olives or parts thereof, either proceeding from three-phase or two-phase presses. This process enables to obtain, by separation and with purities higher than 80%, of both acids with yields comprised between 0.2 and 1.5%, as a function of the product and prime material processed. Fundamentally, it comprises selective extractions and fractionation of resulting mixtures with the use of solvents.
Patent DE-69716731-D1 (DE)
Inventor: GIBIER GILLES
IPC: B65H35/00
Filed: 1997-06-02
Granted: 2002-12-05
Abstract: PCT No. PCT/FR97/00956 Sec. 371 Date Dec. 2, 1998 Sec. 102(e) Date Dec. 2, 1998 PCT Filed Jun. 2, 1997 PCT Pub. No. WO97/46976 PCT Pub. Date Dec. 11, 1997The invention provides a device for dispensing tickets in the form of segments cut off from a single paid-out strip, the device comprising a two-portion container, each portion of the container carrying a cutter blade, the portions of the container being movable relative to each other between a first relative position in which the blades are in a position to cooperate with each other for cutting off a ticket, and a second relative position in which the blades are remote from each other so as to leave sufficient space between them to give easy access to the path of the strip. According to one of the characteristics of the invention, the device comprises a ticket extractor situated downstream from the blades in the payout direction of the strip, the extractor comprising respective rollers coupled to each of the portions of the container such that, in the first above-mentioned position, the rollers are in contact with each other along a generator line, and, in the second position, the rollers are spaced apart from each other by a distance that is not less than the distance between the blades when in their second position.
Patent DE-69717080-D1 (DE)
Inventor: SONERUD AKE
IPC: E02F3/36
Filed: 1997-02-17
Granted: 2002-12-19
Abstract: A coupling arrangement for coupling a working implement to a working machine and being of the kind in which the two coupling parts are mutually connected both mechanically and hydraulically with no manual handling of the coupling arrangement. The machine-mounted coupling part has a drive means for moving associated hydraulic coupling connection means into coupling engagement with hydraulic coupling means on the implement-mounted coupling part, when coupling the machine and implement. The hydraulic coupling connection on the implement-mounted coupling part is movable in the direction of maneuvering movement of the hydraulic coupling, and is moved by the drive means via the hydraulic coupling connection on the machine-mounted coupling part until coming into abutment with an abutment means on the machine-mounted coupling part. The arrangement includes springs that function to exert a pressure that is opposed to this movement. The arrangement ensures that the clearance required for this mechanical coupling will not prevent effective and positive connection of the hydraulic couplings.
Patent DE-69722960-D1 (DE)
Inventor: THYBERG CONNY
IPC: F03B3/12
Filed: 1997-04-25
Granted: 2003-07-24
Abstract: PCT No. PCT/SE97/00698 Sec. 371 Date Oct. 20, 1998 Sec. 102(e) Date Oct. 20, 1998 PCT Filed Apr. 25, 1997 PCT Pub. No. WO97/41347 PCT Pub. Date Nov. 6, 1997A device is used in a hydraulic machine of the type which comprises a runner or rotor with a hub body and vanes or blades which are rotatably journalled in bearings in the hub body, and which has at least one chamber which communicates with the bearings. The device comprises an oil supply to the bearings and elements for leading oil away from the chamber at pace with the supply of oil, such that the chamber is caused to contain an essentially constant volume of oil, which is smaller than the total volume of the chamber, which oil volume is pressed towards the peripheral wall of the chamber by the centrifugal force at the rotation of the runner.
Patent DE-69726143-D1 (DE)
Inventor: NINKOV DUSAN
IPC: A61K31/045
Filed: 1997-09-30
Granted: 2003-12-18
Abstract: The invention relates to pharmaceutical compositions comprising carvacrol and/or thymol as active agents as well as their use in the human and veterinary field. For instance, the compositions according to the invention can be used in the treatment of histomoniasis, an infectious disease of poultry, mainly of turkeys, in the treatment against hemoflagellates and in the treatment of inflammation diseases like pneumonia, nephritis, metritis, artritis, etc. Preferably the active agents are available in the form of an oil, extracted from a group of plants, like Origanum vulgaris, Thymus vulgaris and Mentha piperita
Patent DE-69727843-D1 (DE)
Inventor: LAMOREAUX BEN
IPC: E01B25/16
Filed: 1997-12-05
Granted: 2004-04-01
Abstract: An improved cableway system for providing a track over which a vehicle traverses is disclosed. The improved system includes a catenary cable system (16) and a pair of track cable systems (14). The track cable systems (14) are hung from the catenary cable system (16) and support tracks over which a vehicle (12) traverses. A plurality of hangers (27) is employed to suspend the track cable systems (14) from the catenary cable system (16). A plurality of pylons (17) support the catenary and track cable systems (14,16). A pylon (17) includes a base pylon (21), a lower saddle (200), and an upper saddle (30). The lower saddle (200) is pivotally mounted to the base pylon (21) and supports the track cable systems (14). Preferred embodiments of the lower saddle (200) include apparatuses that dampen the application of loads to the pylon (17) by the vehicle (12) traversing the system. The upper saddle (30) is supported by the base pylon (21) and supports the catenary cable system (16) while providing for deflection of the catenary cable system (16) in response to forces applied to the cableway system. A preferred embodiment of the cableway system includes a force-equalizing assembly (300) for joining the catenary cable system (16) to the track cable system (14) at points between support pylons (17) to equalize the tension in the cables among the various cables. <IMAGE>
Patent DE-69736336-D1 (DE)
Inventor: SAMSOONDAR JAMES
IPC: G01N33/49
Filed: 1997-10-16
Granted: 2006-08-24
Abstract: A method is disclosed whereby the concentration of a blood substitute, such as cross-linked hemoglobin, in a serum or plasma specimen is rapidly and accurately identified and quantified. The method further takes the measured concentration of the blood substitute and uses it to correct for its effect, if any, on a measured analyte concentration, e.g., serum/plasma total protein. Further, the method allows for the determination of the concentration of true hemoglobin in the presence of blood substitutes. The method is carried out in respect of samples contained in a primary or secondary labelled tube, or a pipette tip used to dispense serum or plasma in a blood analyzer.
Patent DE-69738910-D1 (DE)
Inventor: NISHI KENJI
IPC: G03F7/20
Filed: 1997-11-28
Granted: 2008-09-25
Abstract: An exposure apparatus for forming a predetermined pattern on a sensitive substrate comprises: 
a first holding member (WS1b) which holds a sensitive substrate; 
a second holding member (WS2b) which holds a sensitive substrate; 
a first movable member (WS1a) which is used alternately for the first and second holding members (WSlb, WS2b) and is movable in a two-dimensional plane while supporting one holding member (WS1b) of the first and second holding members in order for a measurement of the sensitive substrate held by the one holding member (WS1b); 
a second movable member (WS2a) which is used alternately for the first and second holding members (WS1b, WS2b) and is movable in a two-dimensional plane while supporting the other holding member (WS2b) in order for an exposure of the sensitive substrate held by the other holding member (WS2b); 
a first measurement system (Xe, Ye) which obtains positional information of the one holding member (WS1b) held by the first movable member (WS1a); and 
a second measurement system (Xa, Ya) which obtains positional information of the other holding member (WS2b) held by the second movable member (WS2a).
Patent DE-69803044-D1 (DE)
Inventor: LEVECQ XAVIER
IPC: G01S11/00
Filed: 1998-03-20
Granted: 2002-01-31
Abstract: The invention concerns an optical device for the contactless measurement of the distance of a light source (4) comprising optical detecting means (7) consisting of elementary sensors and further comprising: a set of N imaging means (SP1, SP2, SP3), N>=3, that enable image acquisition of the light source on a plane in the proximity of the detecting means thereby forming with said means a set of hot spots, each spot spreading over at least two elementary sensors; a circuit for computing, on the basis of the relative positions of at least three hot spots, at least one characteristic parameter of the distance from the light source whereof the accuracy depends on N number of hot spots. The measuring device is characterized in that it is designed for industrial measurements (of dimensions, texture, position, vibrations, displacement).
Patent DE-69812584-D1 (DE)
Inventor: VAN DER LELY CORNELIS
IPC: A01J7/00
Filed: 1998-07-09
Granted: 2003-04-30
Abstract: A construction including an implement for automatically milking animals, such as cows, which implement comprises teat cups (16) which are capable of being connected to the teats of an animal to be milked, and which implement comprises separate cups (20) having an other function than teat cups and which can be connected to the teats of an animal, characterized in that the separate cups (20) have a larger diameter than the teat cups (16). <IMAGE>
Patent DE-69813241-D1 (DE)
Inventor: COURT ANDREW D
IPC: A61F13/02
Filed: 1998-08-14
Granted: 2003-05-15
Abstract: The present invention relates to a multi-layered wound dressing particularly for use as a dressing on highly exudating wounds.
Patent DE-69817591-D1 (DE)
Inventor: DAUNAY JACQUES
IPC: F24F13/04
Filed: 1998-09-18
Granted: 2003-10-02
Abstract: A device for regulating the temperature of premises by a secondary air flow blown therein, comprises an upstream duct communicating with elements for supplying pressurized air, ending in a converging element emerging into a downstream duct communicating with the premises. The device is characterized in that a substantially rotating solid, capable of being positioned along the convergent element longitudinal axis, is arranged at least partially upstream of the outlet thereof, so as to define between the substantially rotating solid outer surface and the convergent element inner wall with a ring-shaped channel the size of which depends on the position of the solid relative to the wall.
Patent DE-69821953-D1 (DE)
Inventor: POLYCHRONOPOULOS ASSIMIOS
IPC: F24F1/0071
Filed: 1998-05-08
Granted: 2004-04-01
Abstract: With the proposed evaporative air-cooling system, we can achieve the reduction of the temperature of a space by making use of the natural characteristic of water to absorb heat during its vaporization from the body with which it is in contact. It comprises large wet surfaces created with a small mass of water within a limited space due to the activation of the molecular powers of water and of other material with molecular powers relevant to the ones of water. These wet surfaces are thin cloths, made of cotton or other material with features similar to that of cotton, impregnated with water in a controlled manner so that they can be kept wet at all times. These moistened cloths (12) are placed on bodies (G2) inside which the air of the space to be cooled circulates. Thus, when a vaporization is effected from the wet surfaces into the free atmosphere, heat is absorbed by these bodies producing a "vaporization cold" inside them. Likewise, when the air of the cooled spaces circulates inside these bodies, it leaves heat on them causing in this way the temperature of the cooled space to decrease. This decreased temperature can be by many degrees lower than the temperature of the environment depending on the factors affecting the vaporization speed, among which the relative moisture of the environment where these evaporative air cooling systems operate is the principal.
Patent DE-69824115-D1 (DE)
Inventor: MUTHIAH JENO
IPC: C09D163/00
Filed: 1998-10-27
Granted: 2004-07-01
Abstract: A mixture of a self-curing epoxy resin having an equivalent weight of from 100 to 700, a melt viscosity of from 200 to 2000 centipoise at 150 DEG C and a low temperature curing agent is extruded as one component at a temperature below 105 DEG C and the extrudate is cooled and pulverized to form a low temperature curable coating powder. The powder cures at a temperature of from 107 to 149 DEG C and produces a coating having an exceptionally smooth surface with either a low or high gloss.
Patent DE-69827532-D1 (DE)
Inventor: WOOD WILLIAM I
IPC: C07K16/18
Filed: 1998-09-16
Granted: 2004-12-16
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Patent DE-69828775-D1 (DE)
Inventor: NARUSHIMA SHIGEKI
IPC: B21J1/04
Filed: 1998-11-10
Granted: 2005-03-03
Abstract: An apparatus for changing metal molds for plate thickness reducing presses, comprising upper and lower metal mold receivers (28a, 28b) opposed vertically to each other with a transfer line provided therebetween, and capable of being moved toward and away from each other, a mold receiver guide rail (31) provided on the upper metal mold receiver and extending substantially horizontally in the widthwise direction of the transfer line, an upper metal mold (29a) which has rollers (33) therefor rollable along the mold receiver guide rail, and which is fixed to the upper metal mold receiver by these rollers, a fixing member (30) capable of securing the upper metal mold to the upper metal mold receiver, a lower metal mold (29b) placed on the lower metal mold receiver (28b), a fixing member (30) capable of securing the lower metal mold to the lower metal mold receiver, metal mold fastening members (38) opposed to side surfaces of the upper and lower metal molds and capable of being combined with the two metal molds, and a metal mold changing mechanism capable of moving one metal mold fastening member substantially horizontally in the widthwise direction of the transfer line. <IMAGE>
Patent DE-69833211-D1 (DE)
Inventor: JOHNSON M
IPC: A61K38/18
Filed: 1998-09-15
Granted: 2006-04-06
Abstract: A novel growth factor, persephin, which belongs to the GDNF/neurturin family of growth factors, is disclosed. The human, mouse and rat amino acid sequences have been identified. Human, mouse and rat persephin genomic DNA sequences have been cloned and sequenced and the respective cDNA sequences identified. In addition, methods for treating degenerative conditions using persephin, methods for detecting persephin gene alterations and methods for detecting and monitoring patient levels of persephin are provided. Methods for identifying additional members of the persephin-neurturin-GDNF family of growth factors are also provided.
Patent DE-69837271-D1 (DE)
Inventor: WEINTRAUB BRUCE D
IPC: A61K38/22
Filed: 1998-09-22
Granted: 2007-04-19
Abstract: The present invention is based upon the discovery that mutant ± subunits and mutant ² subunits each comprising amino acid substitutions relative to the wild type can be produced and assembled to form a mutant TSH heterodimer or TSH analog that possesses higher bioactivity  in vitro  and longer half life  in vivo.  Accordingly, the present invention provides methods for using mutant TSH heterodimers, TSH analogs, fragments, and derivatives thereof for treating or preventing diseases of the thyroid, in particular thyroid cancer. The invention also relates to methods of diagnosis, prognosis and monitoring for thyroid-related functions. Pharmaceutical and diagnostic compositions, methods of using mutant TSH heterodimers and TSH analogs with utility for treatment and prevention of metabolic and reproductive diseases are also provided.
Patent DE-69901886-D1 (DE)
Inventor: CHATWIN EDWARD
IPC: B42D15/10
Filed: 1999-03-03
Granted: 2002-07-25
Abstract: A method of manufacturing a security item comprises coextruding at least two polymer plastic materials (6,7) with different characteristics so as to form a substrate so that neither material are biaxially oriented, and providing security indicia (14) on the substrate.
Patent DE-69909238-D1 (DE)
Inventor: HABBAL MOHAMMAD ZOUHEIR DR
IPC: G01N33/72
Filed: 1999-04-21
Granted: 2003-08-07
Abstract: Use of dimethylformamide (I) as accelerator in the determination of bilirubins (II) in serum. Independent claims are also included for the following: (1) a reagent for determination of (II) comprising (I), zinc sulfate and 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (III); and (2) a method for determining (II) comprising: (i) treating serum with sodium nitrite and sulfanilic acid in presence of the reagent of (a); (ii) adding 2-aminoethanol (IV), optionally mixed with (I); and (iii) measuring absorbance.