baber/WOPTO huggingface dataset:
Patent AU-2003263534-B2 (AU)
Title: Improved bacterial outer membrane vesicles
Inventor: RAPPUOLI RINI
IPC: A61K39/00
Filed: 2003-09-01
Granted: 2010-08-05
Abstract: Existing methods of meningococcal OMV preparation involve the use of detergent during disruption of the bacterial membrane. According to the invention, membrane disruption is performed substantially in the absence of detergent. The resulting OMVs retain important bacterial immunogenic components, particularly the protective NspA surface protein. A typical process involves the following steps: (a) treating bacterial cells in the substantial absence of detergent; (b) centrifuging the composition from step (a) to separate the outer membrane vesicles from treated cells and cell debris, and collecting the supernatant; (c) performing a high speed centrifugation of the supernatant from step (b) and collecting the outer membrane vesicles in a pellet; (d) re-dispersing the pellet from step (c) in a buffer; (e) performing a second high speed centrifugation in accordance with step (c), collecting the outer membrane vesicles in a pellet; (f) re-dispersing the pellet from step (e) in an aqueous medium.
Patent AU-2003302734-B2 (AU)
Title: Proteorhodopsin mutants with improved optical characteristics
Inventor: JENSEN RASMUS B
IPC: G11B7/246
Filed: 2003-11-26
Granted: 2009-03-26
Abstract: The present invention is directed to a proteorhodopsin mutant having improved optical characteristics. One improved optical characteristic is having a lower pH (pKrh) at which equal concentrations of the acidic and basic spectral form of the proteorhodopsin molecules are present. Another improved optical characteristic is having a smaller difference in maximum absorption wavelength between the basic and the acidic form. The mutant comprises a mutation in a conserved amino acid residue of a proteorhodopsin variant, which causes spectral shifts. A preferred mutation site is a conserved histidine residue at amino acid position 75 of Bac31A8, or position 77 of Hot75m1, or its equivalent position of a proteorhodopsin variant. Another preferred mutation site is a conserved arginine residue at amino acid position 94 of Bac31A8, or position 96 of Hot75m1, or its equivalent position of a proteorhodopsin variant.
Patent AU-2004203682-B2 (AU)
Title: Aprotinin and analogs as carriers across the blood-brain barrier
Inventor: BELIVEAU RICHARD
IPC: A61P35/00
Filed: 2004-01-05
Granted: 2009-10-01
Abstract: The present invention relates to improvements in the field of drug delivery. More particularly, the invention relates to a non-invasive and flexible method and carrier for transporting a compound or drug across the blood-brain barrier of an individual. In particular the present invention relates to a carrier for transporting an agent attached thereto across a blood-brain barrier, wherein the carrier is able to cross the blood-brain barrier after attachment to the agent and thereby transport the agent across the blood-brain barrier. The present invention relates to improvements in the field of drug delivery. More particularly, the invention relates to a non-invasive and flexible method and carrier for transporting a compound or drug across the blood-brain barrier of an individual. In particular the present invention relates to a carrier for transporting an agent attached thereto across a blood-brain barrier, wherein the carrier is able to cross the blood-brain barrier after attachment to the agent and thereby transport the agent across the blood-brain barrier.
Patent AU-2004218414-B2 (AU)
Title: Tissue processing system
Inventor: SEEGERT CHARLES
IPC: A61B/
Filed: 2004-03-01
Granted: 2009-11-05
Abstract: A tissue processing system includes a series of blades arranged in parallel to form a tissue processor. The blades may be adjusted to create a spaced between each blade in the range of 250-1000 microns. A slicer is included to remove a donor tissue to be processed by the processor. The processor is rotatable 90 degrees so as to create uniform micrografts of tissue for transplanting to a recipient site. An extractor is included to remove tissue particles from the processor after they have been cut into an appropriate size. A cutting block may be provided to ensure uniform thickness of cuts of the donor tissue.
Patent AU-2004258186-B2 (AU)
Title: Cage nut assembly having stand-offs
Inventor: CLINCH JAMES PATRICK
IPC: F16B39/284
Filed: 2004-07-13
Granted: 2009-12-10
Abstract: A cage nut assembly includes a nut and a cage wrapped therearound. The nut and/or the cage are provided with a number of stand-offs. The stand-offs reduce the amount of bearing surface interface between the cage and the nut thus reducing the possibility that the two parts will stick to each other after a bath is applied to the mating surface, and thus to the cage nut assembly, as the cage is welded to the mating surface. The stand-offs can be configured such that the cage nut assembly can move through the bath in a horizontal position, an upside down position, or a sideways positions, substantially without the cage and nut sticking to one another.
Patent AU-2004267057-B2 (AU)
Title: Printer with a pivoting gear mechanism
Inventor: CARRIERE RICHARD L
IPC: B41J3/407
Filed: 2004-08-09
Granted: 2010-04-29
Abstract: A printer, suitable for use in a hand held printer, having a dual direction drive mechanism for driving ink ribbon in a forward feed direction and a reverse feed direction. The drive mechanism is mounted in a printer body, and includes a stationary gear drive assembly engageable with a pivotal drive gear assembly having a forward feed position and a reverse feed direction.
Patent AU-2005210651-B2 (AU)
Title: Preforms made of two or more materials and processes for obtaining them
Inventor: HILL SIMON DAVID JULIAN
IPC: B65D1/02
Filed: 2005-02-01
Granted: 2008-10-09
Abstract: Process for making preforms made of two different materials wherein the first material (4) and the second material (22) are injected with nozzles having center axis that are not coaxial.. Preferably the preforms comprise an inclusion of the second material within the lateral wall of the first material. The new preforms preferably comprises a bottom region (1c) and a lateral wall region (1b), wherein the bottom region is entirely made of the first material and the lateral wall region is generally made of the first material (4) with the exception of at least one volume (14) which is filled by the second material (22). <IMAGE>
Patent AU-2005245338-B2 (AU)
Title: Integration of sample storage and sample management for life science
Inventor: ROLF MULLER
IPC: G06K19/07
Filed: 2005-04-08
Granted: 2011-11-17
Abstract: Compositions and methods are disclosed for automated storing, tracking, retrieving and analyzing biological samples, including dry storage at ambient temperatures of nucleic acids, proteins (including enzymes), and cells using a dry storage matrix that permits recovery of biologically active materials. RFID-tagged biological sample storage devices featuring dissolvable or dissociable matrices are described for use as supports of biological samples, which matrices can be dried and subsequently rehydrated for sample recovery. Also disclosed are computer-implemented systems and methods for managing sample data.
Patent AU-2005252275-B2 (AU)
Title: Tumor specific antibody
Inventor: MACDONALD GLEN CHRISTOPHER
IPC: A61K47/48
Filed: 2005-06-10
Granted: 2011-07-21
Abstract: The present invention provides the amino acid and nucleic acid sequences of heavy chain and light chain complementarity determining regions of a tumor specific antibody. In addition, the invention provides tumor-specific antibodies and immunoconjugates comprising the tumor-specific antibody attached to a toxin or label, and methods and uses thereof. The invention also relates to diagnostic methods and kits using the tumor-specific antibodies of the invention.
Patent AU-2005260732-B2 (AU)
Title: Intraluminal medical device having asymetrical members
Inventor: RAMESH MARREY
IPC: A61F2/06
Filed: 2005-06-30
Granted: 2011-08-25
Abstract: This invention relates generally to expandable intraluminal medical devices for use within a body passageway or duct, and more particularly to an optimized stent having asymmetrical strut and loop members. In one embodiment of the invention the stent includes one or more members each having at least one component such as an arc or a strut. The component has non-uniform cross-sections to achieve near-uniform stress distribution along the component when the component undergoes deformation.
Patent AU-2005273748-B2 (AU)
Title: Insulation panel provided with air tight and rain screen coating and a waterproof coating
Inventor: BAREFOOT STEPHEN O
IPC: E04B1/80
Filed: 2005-07-25
Granted: 2010-09-23
Abstract: A previously formed unitary building exterior envelope product is provided, comprising: a mineral fiber insulation board including a binder having a hydrophobic agent and is resistant to liquid water-penetration and has first and second major surfaces, an exterior facing material, which resists air infiltration and liquid water penetration, laminated to the first major surface, the exterior facing material being permeable to water vapor, and a continuous interior facing laminated to the second major surface, so that the second major surface is resistant to liquid water-penetration and is permeable to water vapor. The section of product is mounted to an exterior side of a plurality of framing members of an exterior wall of a building, so that the interior facing faces the framing members. An exterior layer is mounted to the framing members using a connection device that passes through the section of product, with the facing material facing the exterior layer.
Patent AU-2005286720-B2 (AU)
Title: Carrier system
Inventor: HARLAND MURDOCH DOUGLAS
IPC: A45C1/04
Filed: 2005-09-19
Granted: 2011-07-14
Abstract: A system for carrying articles on a user’s belt, comprising a belt (10) having multiple loops (22) on its outside surface and an article carrier (1) having a sleeve (40) sewn to the body of the carrier at a first end (42) and detachably connected to the body of the carrier at a second end (44). A stiff tab (60) is sewn at one end thereof into the sewn connection of the body of the carrier to the sleeve. The other end of the tab (64) is unattached and overlapped by the sleeve when the sleeve is wrapped around the belt for supporting the carrier from the belt. The carrier can be moved along the belt and placed in different positions unless the free end of the tab is inserted through a loop on the belt in which case the carrier will be fixed in position with respect to the belt.
Patent AU-2006228950-B2 (AU)
Title: Occlusion detector for dual-port surgical tourniquet systems
Inventor: MCEWEN JAMES A
IPC: A61B17/135
Filed: 2006-03-29
Granted: 2011-08-25
Abstract: A occlusion detector for a dual-port surgical tourniquet system comprises: a tourniquet cuff for encircling a patient's limb and including an inflatable portion that communicates pneumatically with a first cuff port and that communicates pneumatically with a second cuff port independently of the first cuff port; a tourniquet instrument that is releasably connectable to the first and second cuff ports to establish first and second pneumatic passageways between the tourniquet cuff and the tourniquet instrument, wherein the tourniquet instrument includes pressure sensing means communicating with the first pneumatic passageway for producing an indication of the pressure in the cuff over a time period suitably long for the performance of a surgical procedure, pressure regulation means communicating with the second pneumatic passageway for regulating the pressure in the cuff near a reference pressure level, and an occlusion detector for introducing a pneumatic pressure pulse into the first pneumatic passageway during an occlusion detection time period, for monitoring the pressure in the second pneumatic passageway during the occlusion detection time period, and for producing an occlusion alarm if a fluctuation of pressure in the second pneumatic passageway is not detected within the occlusion detection time period.
Patent AU-2006258004-B2 (AU)
Title: Methods and kits for sense RNA synthesis
Inventor: GETTS ROBERT C
IPC: C12P19/34
Filed: 2006-06-08
Granted: 2012-09-06
Abstract: Methods and kits are provided for performing multiple rounds of sense RNA synthesis. The sense RNA molecules can be used in various research and diagnostic applications, such as gene expression studies involving nucleic acid microarrays.
Patent AU-2006299429-B2 (AU)
Title: Fc variants with optimized Fc receptor binding properties
Inventor: CARMICHAEL DAVID F
IPC: C07K16/00
Filed: 2006-10-03
Granted: 2012-02-23
Abstract: The present invention relates to Fc variants with optimized Fc receptor binding properties, methods for their generation, Fc polypeptides comprising Fc variants with optimized Fc receptor binding properties, and methods for using Fc variants with optimized Fc receptor binding properties.
Patent AU-2007207116-B2 (AU)
Title: Foam-forming composition
Inventor: BOUTIGNON FRANCOIS JEAN-LOUIS JEROME
IPC: A61K31/573
Filed: 2007-01-12
Granted: 2012-08-02
Abstract: The present invention relates to a novel foam-forming composition suitable for rectal administration of locally-acting pharmaceutically active ingredients, and the product adapted to administer said foam-forming composition. Also, the present invention relates to a method for its preparation. According to the present invention a foam-forming composition is provided which exhibits a high expansion ratio and at the same time conferring optimal appearance of the formed foam to allow sufficient contact time of the active to the target site in the intestine in order to obtain optimal local effect. The composition according to the present inventions provides superior properties for the treatment of rectal diseases.
Patent AU-2007238403-B2 (AU)
Title: A storage and drinking container
Inventor: O'BRIEN MICHAEL
IPC: B65D51/16
Filed: 2007-03-23
Granted: 2013-01-24
Abstract: A storage and drinking container for pressurised beverages comprises a drinking vessel (1) having a lip (3) and a lid formed from a cap (5) and retaining ring (12). The cap (5) seals with a sealing surface (4) on the inside of the neck of the drinking vessel and is retained in place by fingers (8) engaging under a lip (3). The fingers 8 are retained in position by a retaining ring (12). Cooperating sets of cammed surfaces (10) and (13) on the cap (5) and retaining ring (12) act on rotation of the retaining ring to axially separate the retaining ring (12) from the cap (5), releasing the fingers 8 from under the lip (3) and permitting the lid to be removed. The invention provides a drinking vessel with a wide neck which can be reliably sealed without the necessity to provide screw threads on the outer surface of the drinking vessel (1).
Patent AU-2007241576-B2 (AU)
Title: Mechanical barrier in wound healing
Inventor: UGANDER MARTIN
IPC: A61B17/00
Filed: 2007-02-27
Granted: 2012-12-20
Abstract: The present invention relates to an implantable, disposable barrier disc to be used in negative pressure treatment of wounds, in particular sternotomy wounds, wherein the barrier disc consists of a rigid material withstanding a negative pressure of at least -50 mmHg without causing deformation to the barrier disc, and that the barrier disc is perforated to allow drainage of wound fluid through said barrier disc.
Patent AU-2007271829-B2 (AU)
Title: Improvements relating to biocidal compositions
Inventor: JOHN DUNCALF DAVID
IPC: A23L27/00
Filed: 2007-06-29
Granted: 2011-10-27
Abstract: The invention provides a solvent-free biocidal composition of improved efficacy comprising at least one water insoluble biocide (preferably a herbicide) and a water-soluble carrier material, wherein the water-insoluble biocide is dispersed through the carrier material in nano-disperse form having a peak diameter of the nano-disperse form below 1000nm. The invention also provides a process which comprises spray drying a solution of the biocide and a solution of a water- soluble carrier to obtain a solvent free dispersion of the biocide in the carrier, which, when dissolved in water, produces a nano-disperse biocide. The invention also provides an aqueous dispersion of a water insoluble biocide and a water-soluble carrier obtained by the dispersion of the composition of the solvent free composition in water.
Patent AU-2007325978-B2 (AU)
Title: Adoptive transfer of CD8+ T cell clones derived from central memory cells
Inventor: BERGER CAROLINA
IPC: A01N63/00
Filed: 2007-10-12
Granted: 2014-06-19
Abstract: The present invention provides a method of carrying out adoptive immunotherapy in a primate subject in need thereof by administering the subject a cytotoxic T lymphocytes (CTL) preparation in a treatment-effective amount. The method comprises administering as the CTL preparation a preparation consisting essentially of an in vitro expanded primate CTL population, the CTL population enriched prior to expansion for central memory T lymphocytes, and depleted prior to expansion of effector memory T lymphocytes. In some embodiments, the method may further comprise concurrently administering Interleukin-15 to the subject in an amount effective to increase the proliferation of the central memory T cells in the subject. Pharmaceutical formulations produced by the method, and methods of using the same, are also described.
Patent AU-2007352537-B2 (AU)
Title: Aluminum hydroxide
Inventor: HERBIET RENE GABRIEL ERICH
IPC: C01F7/023
Filed: 2007-06-21
Granted: 2013-01-10
Abstract: Aluminum hydroxide f lame-retardants and their use.
Patent AU-2008200302-B2 (AU)
Title: System for resolving tuner conflict
Inventor: VOGEL PETER SAMUEL
IPC: G11B27/02
Filed: 2008-01-22
Granted: 2013-09-05
Abstract: An improved DVR can record programs received in part from a local tuner and in part from another source such as the Internet. This ensures that parts of recordings are not missed due to schedule inaccuracies or tuner conflicts. 5 Programs are normally recorded off-air using the local tuners. If a problem results in a section of a recording being missed, a request is sent to a central office to connect the DVR to a video stream from a suitable tuner at the office via a network such as the Internet. By recording the majority of the desired program locally within the DVR, utilisation of network bandwidth is minimal 10 and the invention can be used even in situations where the Internet bandwidth is insufficient for realtime streaming. Antenna. 1 ................ Tuner2 Caches Tuner3 Cache6 Server S Tuner4 Cache 7 Antenra 10 Antenna 11 Internet 9 Antenna 12 -DVR 15 Fig. 1
Patent AU-2008244588-B2 (AU)
Title: Multiple location load control system
Inventor: STEINER JAMES P
IPC: H05B37/02
Filed: 2008-04-23
Granted: 2012-04-05
Abstract: A multiple location load control system comprises a main device and remote devices, which do not require neutral connections, but allow for visual and audible feedback at the main device and the remote devices. The main device and the remote devices are adapted to be coupled in series electrical connection between an AC power source and an electrical load, and to be further coupled together via an accessory wiring. The remote devices can be wired on the line side and the load side of the load control system, such that the main device is wired "in the middle" of the load control system. The main device is operable to enable a charging path to allow the remote devices to charge power supplies through the accessory wiring during a first time period of a half-cycle of the AC power source. The main device and the remote devices are operable to communicate with each other via the accessory wiring during a second time period of the half-cycle.
Patent AU-2008270648-B2 (AU)
Title: 4-Chloro-4-alkoxy-1,1,1-trifluoro-2-butanones, their preparation and their use in preparing 4-alkoxy-1,1,1-trifluoro-3-buten-2-ones
Inventor: BLAND DOUGLAS
IPC: C07C49/255
Filed: 2008-06-26
Granted: 2013-08-22
Abstract: 4-Chloro-4-alkoxy-1,1,1-trifluoro-2-butanones, prepared by reacting alkyl vinyl ethers with trifluoroacetyl chloride, are useful for preparing 4-alkoxy-1,1,1-trifluoro-3-buten-2-ones.
Patent AU-2008288700-B2 (AU)
Title: A means of stripping concrete formwork from a concrete surface
Inventor: ROSATI WASYL
IPC: E04G19/00
Filed: 2008-08-21
Granted: 2014-07-03
Abstract: The invention is a frame for use with formwork to support the formwork for concrete casting and for stripping formwork from a concrete surface where a frame (16, 23) is moveable between a first and second position that supports and holds formwork in place for concrete casting in a first position and that retracts to a second position so as to lower the formwork away from the concrete surface wherein sufficient force is applied to the formwork as the frame retracts to the second position to strip it from the concrete surface. The invention provides a means of both supporting formwork during concrete casting as well as a means of stripping and lowering the formwork after the concrete is cast.
Patent AU-2008304584-B2 (AU)
Title: Articles prepared using recycled materials and methods of preparation thereof
Inventor: SKAJA JOE
IPC: A43B13/04
Filed: 2008-09-23
Granted: 2013-02-14
Abstract: The present invention is directed to articles of manufacture having at least a portion prepared using recycled material, including but not limited recycled rubber or other polymeric materials. The articles may incorporate the recycled materials in a granulated form. In specific embodiments, the article comprises an article of footwear (i.e., a shoe). Particularly, all or part of the shoe sole may be formed using the granulated material, the granules specifically being joined together using a binder material, such as a polyurethane, preferably a moisture cure, single component polyurethane binder. The invention further provides methods of preparing articles formed of granulated materials. The inventive methods are characterized by their excellent economic benefits, ease of use, and environmental benefits.
Patent AU-2008307735-B2 (AU)
Title: Sensitive and rapid methods of using chimeric receptors to identify autoimmune disease
Inventor: LI YUNSHENG
IPC: C12N15/00
Filed: 2008-09-24
Granted: 2014-04-24
Abstract: The present invention provides methods and compositions useful in the diagnosis and management of autoimmune diseases. In particular, the present invention provides improved methods and compositions for the diagnosis and management of Graves' disease. The methods of the present invention not only avoids the need for radioactivity and are much simpler, economical, and rapid than methods traditionally used for the diagnosis of Graves' disease, but also improve upon the sensitivity and detection abilities of previous luciferase-based autoantibody detection assays. Such improvements are based upon the superior performance of assays comprising a chimeric TSH receptor in the presence of a glucocorticoid including, but not limited to, dexamethasone.
Patent AU-2008307945-B2 (AU)
Title: Method and apparatus for user equipment interaction with a network using interaction information
Inventor: CRAIG BISHOP
IPC: H04W92/04
Filed: 2008-05-09
Granted: 2011-12-01
Abstract: A method of operating a communications network and mobile user equipment (UE) in the network includes providing the UE with an algorithm usable with at least one input parameter to derive a quantity of interaction information according to the at least one input parameter, transmitting at least one said input parameter from the network to the UE, using the algorithm with the received at least one input parameter to derive a quantity of interaction information according to the received at least one parameter, and using the derived quantity of interaction information to determine at least one aspect of interaction between the UE and the network.