baber/WOPTO huggingface dataset:
Patent CA-2482633-A1 (CA)
Title: Oligomeric molecules and uses thereof
Inventor: SEKALY RAFICK P
IPC: C07K19/00
Filed: 2003-02-11
Abstract: The present invention relates to novel oligomers that comprise a plurality of monomers that comprises an active moiety and a scaffold moiety. The oligomers may comprise 6-12 monomers or more. The active moiety comprises sequences that interact with other proteins. The scaffold moiety comprises sequences that interact with sequences of scaffold moieties from other monomers to form oligomers.
Patent CA-2485611-A1 (CA)
Title: Method for assessing biofilms
Inventor: LABARBE RUDI WILLY ROGER
IPC: G01N21/64
Filed: 2003-04-28
Abstract: An automated method for measuring the development of a biofilm on a plurality of surfaces using a confocal imaging system including: a) a radiation source system for forming a beam of electromagnetic radiation comprising one or more wavelengths; b) an optical system for directing and focusing said beam onto one or more planes of the object; c) a detection system for detecting electromagnetic radiation emitted from the object and producing image data;  and d) a scanning system for scanning the object in a plurality of planes with the electromagnetic radiation, the method comprising the steps of: i) growing said biofilm on said plurality of surfaces; ii) detecting the presence of one or more fluorescent moieties within the biofilm by scanning the biofilm with electromagnetic radiation in a plurality of planes to produce a plurality of images; and iii) analysing said images by means of a data processing system under the control of computer software to determine the structure of the biofilm.
Patent CA-2487472-A1 (CA)
Title: Sinkable fun toy
Inventor: CHIANG HERMAN
IPC: A63H23/08
Filed: 2004-11-15
Abstract: A sinkable fun toy includes a floater body and a counter weight member. The floater body includes a receiving portion, which has a receiving opening and a stand portion, which has at least one leg for supporting the receiving portion. The counter weight member is received in the receiving opening of the receiving portion. The first and second engaging portions are formed between the receiving portion and the counter weight member and being engaged with each other. After assembled, the floater body and counter weight member being sinkable, sink in water, the receiving portion is kept a desired height from the ground of water by the stand portion. When the first engaging portion and the second engaging portion are disengaged through pressing the counter weight member, the floater body floats on the water but the counter weight member remains in water.
Patent CA-2487590-A1 (CA)
Title: Film-shaped preparations with improved chemical stability containing active substances and method for the production thereof
Inventor: VON FALKENHAUSEN CHRISTIAN
IPC: A61K9/00
Filed: 2003-05-08
Abstract: The invention relates to a film-shaped preparation containing active ingredients for application in the oral cavity or for transmucosal application. The invention is characterised in that the preparation has a peroxide-number which is at the most 40.
Patent CA-2489396-A1 (CA)
Inventor: HUEBNER HARALD
IPC: A61P25/16
Filed: 2003-07-02
Abstract: La présente invention concerne des hétéroarène-carboxamides substitués par N-[(4-phényl-1-pipérazinyl)alkyle] représentés par la formule générale (I), ces composés étant actifs vis-à-vis des neurorécepteurs, ainsi que des composés de 2-ferrocényle de structure analogue représentés par la formule générale (II) et l'utilisation des composés représentés par les formules (I) et (II) pour traiter des maladies du SNC, telles que la schizophrénie, différents types de dépression, des troubles neurodégénératifs, des dysfonctions sexuelles ou une dépendance à la cocaïne, à l'alcool, à l'opiacé ou à la nicotine, ainsi que des glaucomes, des troubles cognitifs, le syndrome des jambes sans repos, le syndrome d'hyperactivité (ADHS), l'hyperprolactinémie, l'hyperprolactinome ou des troubles moteurs associés à la maladie de Parkinson et pour traiter des troubles moteurs induits par la L-DOPA et les neuroleptiques, tels que l'acathisie, le rigor, la dystonie et la dyskinésie. Dans les formules (I) et (II), les substituants sont tels que définis dans la description.
Patent CA-2491015-A1 (CA)
Inventor: ROSS DAVID J
IPC: G06Q30/02
Filed: 2003-07-01
Abstract: Cette invention concerne un système, un procédé et un programme information permettant de recueillir des avis d'utilisateurs quant à des applications et des données au sein d'un réseau de communication sans fil. Le système (100) identifie un utilisateur qui a téléchargé des applications et/ou des données dans un dispositif sans fil (106) et recueille son opinion, de préférence au moyen d'un questionnaire ciblé adressé à un dispositif sans fil.
Patent CA-2493434-A1 (CA)
Inventor: ROSSI ANTHONY J
IPC: B08B15/00
Filed: 2005-01-19
Abstract: An exhaust fan assembly is provided for expelling contaminated air from a building.  The assembly includes a plenum, a fan assembly attached to the plenum, and a windband mounted on top of the fan assembly. The fan assembly is constructed of cylindrical outer and inner walls which define a bearing chamber and surrounding annular space. A  fan driven by a shaft extending downward from the bearing chamber draws exhaust air from the plenum and blows it up through the annular space to a nozzle at the top of the fan assembly.
Patent CA-2493822-A1 (CA)
Inventor: RAJOTTE DANIEL
IPC: G01N33/567
Filed: 2003-08-12
Abstract: This invention relates to methods and compositions for targeting proteins to secretory lysosomes. The invention further provides methods of use in drug screening assays, and methods of purifying secretory lysosomes.
Patent CA-2495464-A1 (CA)
Inventor: SCHWARZ STEFAN
IPC: B21D39/00
Filed: 2003-07-24
Abstract: L'invention concerne un procédé et un dispositif pour assembler un élément plat (2) à un profilé creux (1), ledit élément (2) et le profilé creux (1) étant placés dans un outil de formage par haute pression interne dans une position déterminée l'un par rapport à l'autre, puis assemblés au moyen d'une haute pression interne fluidique appliquée dans le profilé creux (1). L'objectif de l'invention est d'établir une liaison entre l'élément plat (2) et le profilé creux (1) de manière simple et par un processus fiable. A cet effet, un poinçon (6) intégré dans l'outil de formage agit, pendant l'application de la haute pression interne, sur les parois (3, 5) du profilé creux (1) et de l'élément (2), placées l'une contre l'autre et devant être assemblées, de façon à perforer la paroi (3) du profilé creux (1) de telle sorte que la partie découpée (7) reste accrochée par liaison de matière à un point du bord (8) du trou formé et augmente en largeur en direction de son extrémité libre (9), et de sorte qu'une section de la paroi (5) de l'élément (2) soit courbée en forme de languette (10), de même forme que la partie découpée (7), dans le profilé creux (1) de façon à venir en prise à l'arrière du bord (8) du trou formé dans le profilé creux (1).
Patent CA-2497687-A1 (CA)
Title: Endoscopic surgical instrument instrument for aspiration and irrigation
Inventor: TOVEY H JONATHAN
IPC: A61M1/00
Filed: 1992-10-15
Abstract: ~A single lumen cannula for a surgical aspiration and irrigation device, said cannula communicating a fluid source and an aspirating source with a surgical site through said single lumen, said cannula comprising: at least one aperture at a distal end thereof; and means for detachably connecting a surgical tool member at a distal end thereof, said tool member maintaining fluid communication from said surgical site with said lumen of said cannula.
Patent CA-2498460-A1 (CA)
Inventor: DUGAR SUNDEEP
IPC: C07D401/12
Filed: 2003-09-10
Abstract: Certaines formes dûment substituées de pyrimidine et de triazine sont utiles dans le traitement des états associés à une activité plus intense de TGF-.szlig..
Patent CA-2500014-A1 (CA)
Title: Method, device and system for distributing server requests among a cluster of servers that have registered as mobile nodes
Inventor: LEVY-ABEGNOLI ERIC
IPC: H04L29/08
Filed: 2003-10-02
Abstract: Methods and apparatus for processing registration requests by a Home Agent supporting Mobile IP are disclosed. A registration request is received from each of a plurality of Mobile Nodes, the registration request specifying a care-of address. A binding is established between each of the plurality of Mobile Nodes and the associated care-of address, each of the plurality of Mobile Nodes being associated with one another. For instance, the plurality of Mobile Nodes may be statically or dynamically assigned the same Home Address.  A tunnel is then created between the Home Agent and the care-of address for each of the plurality of Mobile Nodes, thereby enabling a server request to be distributed by the Home Agent to one of the plurality of Mobile Nodes via the associated tunnel. For instance, a server request addressed to the Home Address may be forwarded to one of the Mobile Nodes assigned that Home Address.
Patent CA-2500258-A1 (CA)
Title: Procede pour renforcer un objet
Inventor: BLOEMHOF FOKKE
IPC: B32B7/027
Filed: 2003-09-26
Abstract: L'invention concerne un procédé pour renforcer un objet, ce procédé consistant à fixer sur au moins une surface de l'objet une bande, un film ou un fil polymère thermoplastique étiré. La présente invention porte également sur un objet fait de matériau solide thermodurcissable ou thermoplastique, la composition de ce matériau thermoplastique étant sensiblement la même que celle de la bande, du film ou du fil susmentionnés. Le procédé de l'invention comprend éventuellement le recyclage dudit objet renforcé. La bande, le film ou le fil est fixé à l'objet par traitement thermique et/ou par application d'une pression, une couche de mousse pouvant être posée sur au moins une partie du matériau usiné avant l'application d'une couche de couverture sur au moins une partie de la mousse.
Patent CA-2500466-A1 (CA)
Title: Procede de separation des constituants dans un echantillon a l'aide de milieux filtrants a silice traites par silanes
Inventor: GIBSON GARY L
IPC: B01D15/08
Filed: 2003-10-01
Abstract: La présente invention concerne des procédés de séparation d'un ou de plusieurs constituants étudiés d'un échantillon contenant des particules et des matières solubles. Le procédé comprend les étapes consistant: (a) à filtrer un échantillon à travers des milieux filtrants à silice, dont les groupes silanol de surface ont réagi avec un ou plusieurs silanes et (b) à capturer simultanément les particules et à lier un constituant soluble aux milieux filtrants à silice. Le constituant soluble lié étudié est ensuite élué à partir des milieux filtrants à silice. Dans un mode de réalisation de l'invention, les matières solubles indésirables sont capturées par les milieux filtrants à silice traités et le constituant voulu étudié est récupéré de l'écoulement. Dans un autre mode de réalisation de l'invention, les différents constituants étudiés sont récupérés à la fois de l'éluat et de l'écoulement. Les milieux filtrants à silice traités préférés sont la cendre d'écorce de riz traitée par silanes ou la terre à diatomées avec un groupe ammonium quaternaire fonctionnel ou un groupe sulfonate fonctionnel. Les particules convenant à la présente invention sont, par exemple, des micro-organismes.
Patent CA-2501009-A1 (CA)
Title: Cohesive coprecipitates of sulfated polysaccharide and fibrillar protein and use thereof
Inventor: ROCHKIND SEMION
IPC: A61L31/10
Filed: 2003-09-30
Abstract: The present invention concerns cohesive biopolymer gels comprising coprecipitates of sulfated polysaccharides and fibrillar proteins, exemplifi ed by coprecipitates of dextran sulfate and gelatin, useful for clinical applications including as implants for tissue engineering as well as in biotechnology. The cohesive biopolymer gels according to the present inventi on may be used clinically either per se or as a scaffold for a cell-bearing implant, as a depot for sustained release of bioactive agents, or for resear ch and biotechnology.
Patent CA-2501415-A1 (CA)
Title: Method of selecting cells for somatic cell nuclear transfer
Inventor: ECHELARD YANN
IPC: C12N15/85
Filed: 2003-07-14
Abstract: The present invention provides for the production of homozygous primary cells that carry a specific transgenic integration if interest on both chromosomes by bypassing breeding. These cell lines can they be used for the accelerated production of homozygous transgenic animals by somatic cell nuclear transfer.  The invention is thus useful in the production of transgenic ungulate animals capable of producing desired biopharmaceuticals in their milk at higher yield than a comparable heterzygote. By combining the selection techniques of the current invention with somatic cell nuclear transfer it can be applied to large animals, where there is a strong need to shorten the time to homozygosity.
Patent CA-2502785-A1 (CA)
Inventor: GOTSCHLICH EMIL C
IPC: A61K35/74
Filed: 1995-09-25
Abstract: The present invention is directed to nucleic acids encoding glycosyltransferases, the proteins encoded thereby, and to methods for synthesizing oligosaccharides using the glycosyltransferases of the invention. In particular, the present application is directed to identification a glycosyltransferases locus of Neisseria gonorrhoeae containing eve open reading frames for five different glycosyltransferases. The functionally active glycosyltransferases of the invention are characterized by catalyzing reactions such as adding Gal .beta.1~4 to GlcNAc or Glc; adding GalNAc or GlcNAc .beta.1~3 to Gal; and adding Gal .alpha.1~4 to Gal. The glycosyltransferascs of the invention are particularly suited to the synthesis of the oligosaccharides Gal.beta.1~4GlcNAc.beta.1~3Ga1~1~4Glc (a mimic of lacto-N-neotetraose), GalNAc.beta.1~3Gal.beta.1~4GleNAc.beta.1~3G.beta.1~4Glc.beta.1~4 (a mimic ganglioside), and Gal.alpha.1~4Gal.beta.1~4Gi.beta.1~4Hep~R (a mimic of the saccharide portion of globo-glycolipids).
Patent CA-2502974-A1 (CA)
Title: Howling frequency component emphasis method and apparatus
Inventor: TOHYAMA MIKIO
IPC: G10L21/02
Filed: 2005-03-30
Abstract: A method is designed for emphasizing a howling frequency component of a sound signal observed in an acoustic feedback system during an observation period having a predetermined length. The method is carried out by the steps of successively sampling the sound signal from the acoustic feedback system to provide a running set of samples of the sound signal during the observation period such that a total number of the samples in the running set increments each time one or more of new sample is added to the running set until the total number of the samples corresponds to the predetermined length of the observation period, recurrently calculating a running frequency characteristic of the sound signal on a common frequency axis for the observation period from the running set of the samples each time one ore more of new sample is added to the running set, and accumulating the recurrently calculated running frequency characteristics on the common frequency axis so as to emphasize a howling frequency component contained in the sound signal.
Patent CA-2505542-A1 (CA)
Title: Mandelic acid derivatives
Inventor: STAHL CHRISTOPH MARTIN
IPC: C07D295/15
Filed: 2003-11-21
Abstract: The invention is concerned with novel mandelic acid derivatives of formula (I), wherein R1 to R10, X and Y are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit the formation of coagulation factors Xa, IXa and thrombin induced by factor VIIa and tissue factor and can be used as medicaments.
Patent CA-2506210-A1 (CA)
Title: Dispositif de fixation d`un anneau bruleur dans une chambre de postcombustion d`un turboreacteur
Inventor: BUNEL JACQUES
IPC: F01D25/26
Filed: 2005-05-02
Abstract: Dispositif de fixation d'un anneau brûleur sur des bras accroche-flammes (14) dans une chambre de postcombustion d'un turboréacteur, l'anneau brûleur étant formé de secteurs d'anneau (12) placés sensiblement bout à bout et dont les extrémités sont reçues et guidées entre deux plaques (34, 36) parallèles à orientation circonférentielle des bras accroche-flammes (14), et sont immobilisées entre ces plaques (34, 36) par des pièces de verrouillage (52) qui sont elles-mêmes retenues entre les plaques (34, 36) par des moyens de blocage (54, 56) engagés dans des orifices (58, 60, 64) alignés des plaques (34, 36) et des pièces de verrouillage (52).
Patent CA-2507083-A1 (CA)
Inventor: RAJAGOPALAN MAHESH
IPC: G06F15/173
Filed: 2003-11-25
Abstract: Systems and methods are provided for obtaining contact-related information associated with a party using an identifier. The identifier may include a calling party number, a previously-dialed number, and/or a number specified by a user. The identifier could also include an e-mail address, an instant messenger address, a photograph, etc. A request for contact-related information may be initiated by a user and/or a device associated with the user. The request may include an identifier associated with a party. Methods and systems may retrieve contact-related information associated with the party using the identifier. Methods and systems may leverage one or more networks to retrieve the contact-related information. Contact information may be retrieved in order to add a contact to a user~s address book.
Patent CA-2507709-A1 (CA)
Title: Agents diagnostiques et therapeutiques
Inventor: CLARK GEORGINA JANE
IPC: A61K38/17
Filed: 2003-11-28
Abstract: La présente invention concerne d'une façon générale des agents diagnostiques et thérapeutiques. Cette invention concerne, plus particulièrement, des molécules possédant des particularités structurelles caractéristiques des molécules de signalisation de l'immunorégulation (IRS) et qui sont exprimées par des cellules de lignées hématopoïétiques, telles que, en particulier, des leucocytes. Les molécules de cette invention trouvent une grande application, entre autres choses, comme marqueurs de diagnostic de cellules, comme cibles de thérapie cellulaire et comme cibles de médicament validé de façon à moduler la réponse immune et à traiter, prévenir et diagnostiquer une gamme de maladies comprenant le cancer, une maladie génétique, des états inflammatoires et des états associés à la fonction ou à l'activité de cellules hématopoïétiques aberrante. Cette invention concerne aussi des partenaires de liaison de ces molécules tels que, par exemple, des anticorps, des ligands, un adaptateur et d'autres molécules associées à la signalisation, des agonistes et des antagonistes et des techniques de recherche de ces éléments.
Patent CA-2509536-A1 (CA)
Inventor: KISHIMOTO MITSUHARU
IPC: H01M10/24
Filed: 2000-03-27
Abstract: A three-dimensional battery of a layered type comprising plural pairs of unit batteries each comprising a pair of cells connected with a member interposed therebetween that permits passage of an ion but does not permit passage of an electron, a powdered active material put in and suspended in an electrolytic solution filled in one of the cells to discharge the electron, and a powdered active material put in and suspended in an electrolytic solution filled in the other cell to absorb the electron, the plural pairs of batteries being integrally connected in series with conductive current collecting members placed so as to define separating walls of the respective cells and be in contact with the powdered active materials, wherein the cells on opposite sides are provided with current collectors that are in contact with the powdered active materials and respectively function as a cathode and an anode.
Patent CA-2513809-A1 (CA)
Inventor: VORNLOCHER HANS-PETER
IPC: A61K38/00
Filed: 2004-01-21
Abstract: La présente invention se rapporte à l'acide ribonucléique à double brin (ARNdb) qui a une meilleure efficacité d'inhibition de l'expression génique, à des procédés de fabrication de l'ARNdb, et à des compositions pharmaceutiques comprenant l'ARNdb. L'ARNdb comprend un brin d'ARN (un brin d'ARN complémentaire) possédant une région qui est complémentaire au transcrit d'ARN d'au moins une partie du gène cible, et au moins un groupe lipophile lié par covalence. Les ARNdb sont utiles pour inhiber l'expression d'un gène cible ainsi que pour traiter les maladies causées par l'expression du gène cible. L'invention se rapporte à des procédés pour inhiber l'expression d'un gène cible ainsi que des procédés pour traiter les maladies provoquées par l'expression du gène.
Patent CA-2515566-A1 (CA)
Title: Mobile wireless communications device providing enhanced text navigation indicators and related methods
Inventor: SCOTT SHERRYL LEE LORRAINE
IPC: G06F40/237
Filed: 2005-09-13
Abstract: A mobile wireless communications device may include a portable, handheld housing, and a display and keypad carried by the housing. In particular, the keypad may include a plurality of symbol keys each having indicia of at least one respective symbol thereon, and an alternate function key. A user input device and a controller may also be carried by the portable, handheld housing. The controller may be connected to the display and the keypad, and it may generate a menu of possible desired words based upon actuation of the symbol keys, and generate a word cursor in the menu for scrolling through the possible desired words based upon the user input device. The controller may also change the word cursor to a symbol cursor based upon actuation of the alternate function key for scrolling through symbols in the possible desired words based upon the user input device.
Patent CA-2520746-A1 (CA)
Inventor: REED SCOTT W
IPC: A61B17/128
Filed: 1996-10-16
Abstract: A surgical clip applier includes a housing, a pair of handles pivotably connected to opposite sides of the housing, a channel assembly which is anchored to the housing and a jaw assembly which is anchored to the channel assembly. A series of clips are arranged serially in end to end relation and carried by the channel assembly. A clip follower urges the series of clips toward the jaw members. A clip pusher is slidably disposed in the channel assembly for advancing a distalmost clip from the series of clips to a position between the jaw members in response to movement of the handles. A jaw closure mechanism is provided to effect closure of the jaw members to deform a clip positioned therebetween in response to movement of the handles. A lockout mechanism is provided for rendering the clip applier inoperable upon deforming a last clip of the series of clips. The lockout mechanism includes a first blocking member for engagement with the cam plate to prevent movement of the cam plate, and at least one frangible member to disengage the cam plate from the handles upon closure of the handles when first blocking member is engaged with the cam plate.
Patent CA-2522637-A1 (CA)
Inventor: MANOHARAN MUTHIAH
IPC: C12Q1/68
Filed: 2004-04-16
Abstract: The invention relates to iRNA agents, which preferably include a monomer in which the ribose moiety has been replaced by a moiety other than ribose. The inclusion of such a monomer can allow for modulation of a property of the iRNA  agent into which it is incorporated, e.g., by using the non-ribose moiety as a point to which a ligand or other entity, e.g., a lipophilic moiety. e.g., cholesterol, is is directly, or indirectly, tethered. The invention also relates to methods of making and using such modified iRNA agents.
Patent CA-2523866-A1 (CA)
Inventor: MILLER ROBERT J
IPC: E04F13/14
Filed: 2004-04-24
Abstract: A modular tile assembly having a substantially rigid substrate, at least one sealant layer, and at least one stone, ceramic, or porcelain tile. A bottom surface of a first sealant layer being bonded to an upper surface of the substrate and a top surface of a second sealant layer being bonded to a lower surface of the substrate. The tile being bonded to at least a portion of the top surface of the first sealant layer. In one example, the substrate is provided with a tongue or a groove defined in any one, combination, or each of the respective side edges of the substrate, as desired.