baber/WOPTO huggingface dataset:
Patent DE-69432905-D1 (DE)
Inventor: MARIN PER
IPC: B65B1/08
Filed: 1994-08-09
Granted: 2003-08-07
Abstract: An inhibitor (A) of cortisol synthesis is used: (a) to treat type II diabetes mellitus; and (b) to counteract other risk factors that are part of the metabolic syndrome (also known as the deadly quartet, syndrome X or insulin resistance syndrome). (A) is ketoconazole (I; already well known as an antimycotic) or its derivs. with comparable activity. Men treated with (A) may need to receive testosterone, since (A) also inhibits prodn. of this hormone.
Patent DE-69433014-D1 (DE)
Inventor: BUISSON LAURENT
IPC: B05B11/00
Filed: 1994-09-20
Granted: 2003-09-11
Abstract: The present invention pertains to improved manually operated atomization systems which combine atomizing nozzles with high pressure, pre-compression type pump mechanisms in order to provide a consistent, high quality, finely-atomized spray of a comparatively higher viscosity fluid. The pre-compression pump mechanism ensures that the product will only be delivered when sufficient pressure is available for atomization regardless of the speed or authority with which the pump mechanism is actuated. When the fluid is discharged from the nozzle in a swirling, conical film, the fluid is broken up into a finely-dispersed mist which may then be directed toward the surface to be coated. Pump mechanisms for use with the present invention incorporate specific design features which facilitate the flow of comparatively viscous fluids with reduced flow resistance and hence reduced pressure losses, as well as providing enhanced structural integrity to better withstand such operating pressures and forces while providing improved reliability. The combination of pre-compression and comparatively higher operating pressures ensures that the comparatively higher viscosity fluid will be delivered to the nozzle with a pressure (and hence a velocity) that is comparatively high and within a comparatively narrow range. This in turn ensures a finely-dispersed product spray with a comparatively narrow range of particle sizes, under a wide range of actuation circumstances.
Patent DE-69433125-D1 (DE)
Inventor: FENDERSON JOHN MELVIN
IPC: A01N37/26
Filed: 1994-02-15
Granted: 2003-10-16
Abstract: A method of controlling undesired plant growth which comprises co-application to the locus of said undesired plants growth dimethenamid and pendimethalin in a herbicidally effective aggregate amount.
Patent DE-69506422-D1 (DE)
Inventor: SIMON GABRIEL
IPC: A61F2/00
Filed: 1995-08-30
Granted: 1999-01-14
Abstract: The present invention provides a surgical technique and instrument kit that allows for subtle modification of the corneal curvature by interlamellar injection of a synthetic gel at the corneal periphery while sparing the optical zone. The gel viscosity, volume and disposition within the surgical annular track as well as the diameter of the track, width, depth, and location are all parameters in the refractive change obtained. Following ultrasonic pachymetry performed centrally and at a selected wound entrance located about 2.5 to 3.5 mm from the apex, a one millimeter or so wide, about 75-85% corneal thickness depth radial incision is performed with a micrometric diamond knife adjusted to about 86% corneal thickness. Inserted through the partial-depth incision, a corkscrew-like dissector or helicoidal spatula forms a 360 DEG  annular track centered about the apex. A transparent gel is manually injected through the incision, filling the annular channel. Using a surgical keratometer mounted to an operation microscope, the final corneal power is adjusted by massaging and removing the gel as necessary during the primary procedure or subsequent procedures, as the GIAK technique is reversible.
Patent DE-69506688-D1 (DE)
Inventor: PLEWS JACQUELINE
IPC: A61M25/02
Filed: 1995-01-27
Granted: 1999-01-28
Abstract: PCT No. PCT/GB95/00164 Sec. 371 Date Dec. 5, 1996 Sec. 102(e) Date Dec. 5, 1996 PCT Filed Jan. 27, 1995 PCT Pub. No. WO95/20415 PCT Pub. Date Aug. 3, 1995There is described a cannula or catheter dressing comprising a body portion of flexible adherent sheet material for covering a wound site caused by the insertion of a catheter into a patient; and a handle an edge of which defines an aperture for receiving the catheter or cannula wherein the handle comprises a material less flexible than the body portion.
Patent DE-69515201-D1 (DE)
Inventor: GELLERT JOBST ULRICH
IPC: B29C45/30
Filed: 1995-05-08
Granted: 2000-04-06
Abstract: An injection molding nozzle seal around the gate which bridges the insulative air space between the front end of the heated nozzle and the cooled mold. The nozzle seal is provided by two removable inserts mounted in alignment with the central melt bore through the nozzle to convey the melt therethrough forwardly to the gate leading to the cavity. The first insert is screwed into a threaded seat in the front end of the nozzle and the second insert is screwed onto the first insert. The inserts each have a hexagonal portion for engagement by a wrench. Both of the engagement portions extend in the air space around the nozzle which facilitates removal of the inserts for cleaning or replacement without disassembling the mold.
Patent DE-69524578-D1 (DE)
Inventor: ASKIN DAVID
IPC: A61P31/12
Filed: 1995-02-27
Granted: 2002-01-24
Abstract: A process for synthesizing the epoxide of formula (I) consists of, at a minimum, formation of a halohydrin form the allyl acetonide reactant, followed by base-induced cyclization, the epoxide product (I) being useful as an intermediate for the synthesis of inhibitors of renin or HIV protease or other proteases.
Patent DE-69530261-D1 (DE)
Inventor: TONKS NICHOLAS K
IPC: C12N15/55
Filed: 1995-05-03
Granted: 2003-05-15
Abstract: Novel Type III density enhanced protein tyrosine phosphatases are disclosed and exemplified by human DEP-1 enzyme. Polynucleotides encoding huDEP-1 are disclosed, along with methods and materials for production of the same by recombinant procedures. Binding molecules specific for DEP-1 are also disclosed as useful for modulating the biological activities of DEP-1. <IMAGE>
Patent DE-69534714-D1 (DE)
Inventor: MCNEEL E
IPC: G01N27/416
Filed: 1995-01-12
Granted: 2006-02-02
Abstract: A method for controlling the chemical treatment of a solution comprises the steps of feeding a treatment chemical into the solution, applying an external voltage across a reference electrode and a working electrode of a voltammetric sensor while the electrodes are immersed in the solution, measuring a current that flows through the working electrode, converting the measured current into a feedback signal indicative of the concentration of treatment chemical in the solution, and using the feedback signal to control the rate of feeding the treatment chemical.
Patent DE-69616541-D1 (DE)
Inventor: PANESCU DORIN
IPC: A61N1/40
Filed: 1996-04-30
Granted: 2001-12-06
Abstract: Systems and associated methods for ablating body tissue employ an electrode for contacting tissue to form a tissue-electrode interface. The electrode is adapted to be connected to a source of ablation energy to conduct ablation energy for transmission by the electrode into tissue at the tissue-electrode interface. The systems and methods also include an element to cool the electrode. The systems and methods hold a tissue temperature sensing element in a carrier in thermal conductive contact with tissue beneath the tissue-electrode interface. The systems and methods include a controller that is coupled to the tissue temperature sensing element to control either the supply of ablation energy, or the rate at which the electrode is cooled, or both based, at least in part, upon temperature sensed by the temperature sensing element.
Patent DE-69624096-D1 (DE)
Inventor: JOHANSSON HANS
IPC: C07H1/06
Filed: 1996-01-18
Granted: 2002-11-07
Abstract: PCT No. PCT/SE96/00043 Sec. 371 Date Sep. 15, 1997 Sec. 102(e) Date Sep. 15, 1997 PCT Filed Jan. 18, 1996 PCT Pub. No. WO96/22299 PCT Pub. Date Jul. 25, 1996Method for the purification of a synthetic oligonucleotide from failure sequences comprising contacting a sample containing the desired oligonucleotide in protected water-soluble form with a hydrophilic adsorbent exhibiting anion exchange groups under conditions permitting binding of said oligonucleotide to said adsorbent, whereafter the adsorbed oligonucleotide is deprotected and separated from failure sequences. The characteristic feature of the method is to use an anion exchange adsorbent that binds the protected oligonucleotide under conditions of high as well as low ionic strength.
Patent DE-69627269-D1 (DE)
Inventor: PAULMAN ROGER
IPC: F28F1/00
Filed: 1996-10-31
Granted: 2003-05-15
Abstract: A heat exchanger assembly of the side-entry type includes at least one fin set (24) and an elongated heat exchanger tube (12,13,14) having a collapsed sidewall (16) extending substantially the length of the tube which permits the bending of the elongated heat exchanger tube at the return bend portions and permits expansion of the elongated tube (12,13,14) to engage the fin set (24). Method and apparatus for making the elongated heat exchanger tube having the collapsed sidewall substantially extending the length of the tube as well as methods of making heat exchanger assemblies are disclosed.
Patent DE-69629273-D1 (DE)
Inventor: CAVAZZA CLAUDIO
IPC: A61K33/24
Filed: 1996-12-11
Granted: 2003-09-04
Abstract: A pharmaceutical compositions comprising L-carnitine or alkanoyl L-carnitine and hydroxycitric or pantothenic acid or derivatives thereof for the prevention and treatment of diseases brought about by lipid metabolism disorders, is disclosed.
Patent DE-69630191-D1 (DE)
Inventor: FUTAGAWA HITOSHI
IPC: A61M5/315
Filed: 1996-12-20
Granted: 2003-11-06
Abstract: A prefilled syringe comprises a barrel (1) having at a distal end a needle-connecting portion (11) and at the proximal end an open end; a plastic tubular container (3) having a mouth (31) and a flexible hollow cylindrical body (32) and containing a liquid medicament (S) previously charged therein, and a plunger (2) inserted into the barrel (1) through the open end thereof and slidably held therein. The tubular container (3) is held in the barrel (1) so that the mouth (31) thereof is placed in a lumen of the needle-connecting portion (11) of the barrel (1) and that the cylindrical body (32) is peeled off from the inner wall of the barrel (1) and squeezed into a space between the barrel (1) and plunger (2) when the plunger (2) is pushed into the barrel. <IMAGE>
Patent DE-69630622-D1 (DE)
Inventor: TSIEN ROGER Y
IPC: C12Q1/68
Filed: 1996-03-20
Granted: 2003-12-11
Abstract: Substrates for  beta -lactamase of general formula (I) in which one of X and Y is a fluorescent donor moiety and the other is a quencher (which may or may not re-emit); R' is selected from the group consisting of H, lower (i.e. alkyl of 1 to about 5 carbon atoms) and (CH2)nOH, in which n is 0 or an integer from 1 to 5; R" is selected from the group consisting of H, physiologically acceptable metal and ammonium cations, - CHR<2>OCO(CH2)nCH3, -CHR<2>OCOC(CH3)3, acylthiomethyl, acyloxy-alpha-benzyl, delta-butyrolactonyl, methoxycarbonyloxymethyl, phenyl, methylsulphinylmethyl, beta-morpholinoethyl, dialkylaminoethyl, acyloxyalkyl, dialkylaminocarbonyloxymethyl and aliphatic, in which R<2> is selected from the group consisting of H and lower alkyl; A is selected from the group consisting of S, O, SO, SO2 and CH2; and Z' and Z" are linkers for the fluorescent donor and quencher moieties. Methods of assaying  beta -lactamase activity and monitoring expression in systems using  beta -lactamase as a reporter gene also are disclosed. <IMAGE> <IMAGE>
Patent DE-69702143-D1 (DE)
Inventor: DE JONG CORNELIS
IPC: H03F3/45
Filed: 1997-03-24
Granted: 2000-06-29
Abstract: PCT No. PCT/NL97/00148 Sec. 371 Date Dec. 10, 1998 Sec. 102(e) Date Dec. 10, 1998 PCT Filed Mar. 24, 1997 PCT Pub. No. WO97/36371 PCT Pub. Date Oct. 2, 1997An instrumentation amplifier for absolute voltage amplification having a balanced voltage inlet and a balanced voltage outlet. The voltage inlet is coupled to first amplification units having a very high open-loop gain, and which is further coupled with a feedback network provided between the outputs and second inputs of the amplification units.
Patent DE-69705412-D1 (DE)
Inventor: DELMEE EMMANUEL
IPC: B65D81/05
Filed: 1997-07-11
Granted: 2001-08-02
Abstract: A packaging for transporting hazardous materials in one or more containers is disclosed. Said packaging includes a box (1) made of a semi-rigid material such as cardboard; at least one module (2) made of a semi-rigid material such as cardboard and including at least four side interconnected walls (12, 13, 14, 15), said module (2) having a substantially rectangular cross-section and being arranged inside said box (1) and spaced from the walls (4, 5, 6, 7) thereof, while said containers are arranged inside the module; and a filler material made of expanded phyllosilicates, preferably expanded vermiculite, which fills all of the remaining space inside said box (1) and said module (2) containing said hazardous material containers. The production of cardboard packagings, and the use thereof, particularly for packaging hazardous chemicals, are also disclosed.
Patent DE-69712774-D1 (DE)
Inventor: TING L
IPC: C07C45/62
Filed: 1997-10-24
Granted: 2002-06-27
Abstract: A concentrated single phase aqueous alkaline solution of tetrahydroiso- alpha -acids having greater than 10% to about 45% w/w tetrahydroiso- alpha -acids is disclosed. A method of hydrogenating and formulating a starting solution of iso- alpha -acids to obtain such concentrated solutions of tetrahydroiso- alpha -acids is also disclosed.
Patent DE-69713443-D1 (DE)
Inventor: FERREIRA ADOLFO A
IPC: A61F5/445
Filed: 1997-04-25
Granted: 2002-07-25
Abstract: The pouch is formed of first and second thin barrier film walls welded along the periphery to form a waste receptical. One wall has an inlet defined by an attachment ring. The ring mounts the pouch on an adhesive faceplate adapted to adhere to the skin surrounding the stoma. A membrane, formed of material which is gas permeable but transmits little moisture and no liquid, is situated between the walls to separate the receptical into an inlet chamber, where solids, liquid and most moisture are retained, and an outlet chamber into which gas and a small amount of vapor passes. A filter is provided to permit the gas to exit the outlet chamber. A first section of superabsorbent material isolates the filter from the outlet chamber. By absorbing any moisture in the gas before it contacts the filter, blockage of the filter is prevented. A second section of superabsorbant material is provided near the bottom of the output chamber to absorb moisture which otherwise may cause the membrane to stick to the pouch wall, resulting in a substantial reduction of the gas transmissibility of the membrane.
Patent DE-69723661-D1 (DE)
Inventor: JOHANSSON TOR
IPC: A22C13/00
Filed: 1997-12-01
Granted: 2003-08-28
Abstract: The present invention concerns a cellulose-containing casing and a method for manufacture of same. The cellulose-containing casing can be used for enclosing of foods, such as sausage. The casing contains paper and regenerated cellulose as well as a powdery material as a filler material which produces a porous structure in the casing, which speeds up the drying and the time of curing of foods, such as sausages. As the filler agent, it is possible to use, for example, silicon compounds. <IMAGE>
Patent DE-69732220-D1 (DE)
Inventor: DEAN FRANK WILLIAM
IPC: C07F15/06
Filed: 1997-03-21
Granted: 2005-02-17
Abstract: The present invention is directed to methods for solubilizing boric acid to produce liquid, boron-containing solutions. In these methods, boric acid is added to a previously formed solution of a metal ion and ligand. The ligand must be capable of both complexing the metal ion and simultaneously coordinating or hydrogen bonding with the boric acid. Preferred metal ions are the transition metals. Preferred ligands are the alkanolamines, polyamines, dialkylaminoalkylamines and alkyldiaminecarboxylic acids and salts thereof. Using the methods of the present invention, stable, clear solutions, preferrably aqueous solutions, containing about 9-11 percent-by-weight or more boron are readily prepared.
Patent DE-69806128-D1 (DE)
Inventor: MOILLO YVES
IPC: B62J9/00
Filed: 1998-03-16
Granted: 2002-07-25
Abstract: The invention concerns a motorcycle accessory, more particularly a removable cover for a motorcycle fuel tank, comprising a central portion (3) extended by at least two end portions (4, 5) for covering, at least partially, the fuel tank from one edge to the opposite edge, the cover consisting of a substantially rigid shell (1) with an inner surface of shape substantially matching that of the tank and comprising, at each of its end parts (4, 5) independent fixing means (10, 11) for locking the shell on the motorcycle. The invention also concerns a removable luggage carrier.
Patent DE-69808409-D1 (DE)
Inventor: PIGOZZI GIAN MARIA
IPC: F16H37/02
Filed: 1998-11-10
Granted: 2002-11-07
Abstract: A gear change for an automobile vehicle comprising a box (4), a main train, an input shaft of which is connected to the engine and a primary shaft (13) of which can be connected angularly to the input shaft by a plurality of pairs of gears, and an auxiliary epicyclic gear train (3) comprising, in turn, a sun gear (22) angularly coupled to the primary shaft (13), a train carrier (46) angularly rigid with an output shaft (50) of the gear change and comprising a plurality of planet gears (43) engaging with the sun gear (22), and an outer crown (56) having inner teeth (57) engaging with the planet gears (43), which crown (56) can be displaced along the longitudinal axis (A) between a first operating position in which it is coupled to the box (4) by the engagement of a first and a second toothed wheel (59,62) and a second operating position in which it is coupled to the train carrier (46) by the engagement of a third and a fourth toothed wheel (60,63); the sun gear (22), the planet gears (43) and the inner teeth (57) of the crown (56) comprising respective helical teeth (64,65,66) and the first, second, third and fourth toothed wheels (59,62,60,63) comprising respective teeth having a helical flank in order to generate on the crown (56), during operation, a restraining reaction having an axial component adapted at least to balance an axial thrust generated on this crown (56) and tending to displace it from the operating position in which it is located. <IMAGE>
Patent DE-69815826-D1 (DE)
Inventor: ESTLANDER PETER
IPC: A47F1/00
Filed: 1998-02-18
Granted: 2003-07-31
Abstract: A dispenser for bulk goods comprises a storage container, and a discharge device connected thereto, a dosing means and a discharge chute extending to a collecting point. The dosing means comprises a valve flap which is pivotable between a closing position and a discharge position. An operating device is adapted to pivot the valve flap between said two positions. A locking device prevents the valve flap from pivoting from the closing position to the discharge position in the absence of a collecting receptacle or bag at the collecting point. Preferably, the operating device comprises two operating handles which are operatively connected to the valve flap for pivoting thereof. In this operative connection, a sensor mechanism is included, which permits power transfer merely in essentially parallel or synchronous actuation of the operating handles.
Patent DE-69821655-D1 (DE)
Inventor: HILLS ANDREW
IPC: A61P43/00
Filed: 1998-11-26
Granted: 2004-03-18
Abstract: A medicament is disclosed for reducing the risk of cross-healing ("adhesions") after surgery. The medicament is a dry powder comprising a surface active phospholipid which is capable of binding to mesothical membranes, and a spreading agent. The medicament is applied as a dry powder to the surgical wound site.
Patent DE-69827838-D1 (DE)
Inventor: DALEBOUT T
IPC: A63B22/00
Filed: 1998-09-03
Granted: 2004-12-30
Abstract: A foldable treadmill includes a deck having a rear end that is hingedly attached to a stationary base. The deck can be selectively rotated between an operational position, wherein the deck is substantially level, and a storage position, wherein the front end of the deck is lifted so that the deck is substantially upright. The treadmill also includes a handrail that is movably attached to the deck. The handrail has a first end attached to the base and an opposing second end projecting above the front end of the deck when the deck is in the operational position. The handrail is configured to automatically collapse into substantial alignment with the deck when the deck is rotated into the storage position. The deck and the handrail are configured such that the treadmill can be selectively stored against a wall and the deck selectively rotated from the storage position to the operational position causing the handrail to also move without either the deck or handrail contacting the wall. The deck selectively rotates into an operational position in which the handrail extends toward the front of the deck thereby allowing the user to face away from the wall.
Patent DE-69831914-D1 (DE)
Inventor: BADIA SELLARES JOSEP ISIDRE
IPC: E06B9/174
Filed: 1998-11-03
Granted: 2005-11-24
Abstract: The structure comprises a supporting box (1), formed by upper and lower walls (5, 6), two end caps (7), a side wall (8) and a cover (9) each of which is formed by: an association of metallic sections (20), which define two longitudinal edges and an outer surface (16), the outer surfaces of the sections of one same association being coplanar; and by an insulating section (14) which is comprised between two metallic sections (20) of one same association and attached to the longitudinal edges of the metallic sections (20) between which it is situated; each of said insulating sections (14) extends between the insulating sections (14) of the adjacent walls (5, 6) or end caps (7). <IMAGE>
Patent DE-69833484-D1 (DE)
Inventor: JEFFREE STANLEY
IPC: E21B47/10
Filed: 1998-05-13
Granted: 2006-04-20
Abstract: An apparatus and method for testing the integrity of oil delivery tubing within an oil well casing includes a rupture disc holder coupled with the tubing near the lower end thereof. As successive lengths of tubing are added, the assembled tubing is subjected to a test pressure with the pressure maintained by the presence of the rupture disc within the holder. When the tubing assembly is complete, it is subjected to a higher burst pressure sufficient to rupture the disc. This opens a passage through the holder for installation of the push-pull rod and for passage of oil from the pump, which is coupled with the tubing below the level of the holder.
Patent DE-69841418-D1 (DE)
Inventor: KEARNEY MICHAEL M
IPC: C13B20/14
Filed: 1998-01-06
Granted: 2010-02-11
Abstract: A "block" of betaine is displaced from the circulation loop of an ion exclusion system configured as an SMB without disturbing the normal operation of the system. In practice, a betaine-concentrated fraction is withdrawn (17) from the circulating loop of the SMB while an equal volume of water is introduced (15) to the loop. The circulation loop thereby continues without disruption.
Patent DE-69842005-D1 (DE)
Inventor: JOHDO OSAMU
IPC: C07H15/252
Filed: 1998-12-01
Granted: 2010-12-30
Abstract: Disclosed are a crystalline form of anthracycline antibiotic having specific characteristic 2θ values as measured by the X-ray diffraction method, and a process for producing the crystalline form. This process comprises the step of crystallization involving the combined use of a specific poor solvent for the antibiotic and a good solvent therefor. This crystalline form has excellent chemical and physical properties.