baber/WOPTO huggingface dataset:
Patent CA-2498422-A1 (CA)
Inventor: NINOMIYA KEIKO
IPC: C07H21/02
Filed: 2003-09-05
Abstract: It is intended to provide a method of chemically synthesizing an aminoacyl tRNA which is completely different from the existing methods, namely, a high ly efficient and practically usable method of synthesizing an aminoacyl tRNA whereby any unnatural amino acid can by conveniently aminoacylated without a need for genetic engineering techniques and detected without resort to a radioactive isotope. The above-described aminoacylation method comprises enclosing a tRNA and an amino acid in the vicinity of the interface of a micelle and bringing them close to each other to thereby react the same, or providing between them a peptide nucleic acid specifically binding to the tR NA as an antisense molecule and bringing them close to each other to thereby react the same.
Patent CA-2500472-A1 (CA)
Inventor: NAKAMURA YUSUKE
IPC: C12Q1/68
Filed: 2003-09-12
Abstract: The present application provides novel human genes C1958V1 or C1958V2 whose expression is markedly elevated in pancreatic cancers compared to corresponding non-cancerous tissues. The genes and polypeptides encoded by the genes can be used, for example, in the diagnosis of pancreatic cancer, and as target molecules for developing drugs against the disease.
Patent CA-2500911-A1 (CA)
Inventor: SAMUELSEN PETER BOMAN
IPC: A61K39/39
Filed: 2003-10-02
Abstract: The present invention provides novel compositions for transdermal delivery of at least one immunogen to an individual, which compositions comprise (a) said at least one immunogen (b) an occlusion vehicle and (c) an immunogen delivery system in the form of a PosIntro or a cationic ISCOM or comprising at least one saponin and at as well as a process for preparation of the compositions.  The invention further provides constructs comprising these compositions. The compositions and constructs may be used in methods for generating an immunological response, methods for treating or preventing a condition of illness and methods for vaccination. The occlusion vehicle is e.g. a pressure sensitive adhesive, such as a hydrocolloid adhesive or a hydrogel adhesive, which may be cross-linked, or the occlusion vehicle may be non-adherent.
Patent CA-2503234-A1 (CA)
Title: Precast concrete panels for basement walls
Inventor: MACK HOWARD J
IPC: E04C2/06
Filed: 2005-04-18
Abstract: A basement wall is provided which includes a precast prestressed hollow core concrete panel. The panel has a plurality of horizontally extending voids and a plurality of horizontally extending tension cables. The panel has a lower portion extending below grade. The panel preferably has a layer of wire mesh positioned between the voids and the inner surface or between the voids and the outer surface. An end cap for the panel is also provided. The panel can have an impressed brick pattern on the above-grade outer surface and the panel can have a window opening, a brick ledge and/or a beam pocket.
Patent CA-2504156-A1 (CA)
Inventor: MASSARO MICHAEL
IPC: A61K8/92
Filed: 2003-10-22
Abstract: Liquid lamellar cleansing compositions are described that contain synthetic surfactants, hydrophilic emollients and exfoliant particles where 80 % or more of the particles have a major axis length of between 100 and 1000 microns. The combination of the mild surfactants, moisturizers, and exfoliants provide the user with simultaneous moisturization and exfoliation in a convenient liquid cleansing product.
Patent CA-2506888-A1 (CA)
Title: Selective cyclooxygenase-2 inhibitor patch
Inventor: SHIMIZU NORIKO
IPC: A61K31/42
Filed: 2003-11-12
Abstract: A pharmaceutical composition for application to an area of skin of a subject for local and/or systemic treatment of a COX-2 mediated disorder comprises a backing sheet that is flexibly conformable to the area of skin, the backing sheet having opposing surfaces that are respectively distal and proximal to the skin when applied; and a coating on the proximal surface of the backing sheet that comprises (a) an adhesive, (b) an active agent comprising a selective COX-2 inhibitory sulfonamide drug of low water solubility, and (c) a solvent system for the active agent, wherein the active agent is in a therapeutically effective total amount and the solvent system is selected wi th regard to composition and amount thereof to be effective to maintain the active agent substantially completely in solubilized form. A method of local treatment of a site of pain and/or inflammation in a subject comprises applying the composition to a skin surface of the subject, preferably at a locus overlying or adjacent to the site of pain and/or inflammation, and leaving the composition in place for a time period effective to permit delivery of a locally therapeutic amount of the active agent. A method of systemic treatment of a subject having a COX-2 mediated disorder comprises applying the composition to a skin surface of the subject, and leaving the composition in place for a time period effective to permit transdermal delivery of a therapeutic amount of the active agent.
Patent CA-2507473-A1 (CA)
Inventor: HIGNETT IAN HAROLD
IPC: F16L15/04
Filed: 2003-11-25
Abstract: A screw-threaded joint for pipes comprises a first pipe length (10) having a male screw-threaded portion (11) at one end. A second pipe (20) has at one end a female portion having a complementary screw-threaded portion. The pipe lengths are adapted to inter-engage along the greater part of the axial length of the threaded portions the screw threads thereof being inclined in the same direction and at an acute angle to the longitudinal axis of the pipe length.  The male thread (11) extends to a male stop shoulder (15) adjacent a complementary stop shoulder on the other portion. The complementary stop shoulder has a recess in the form of a cone receiver having a rounded apex. A  first conic surface (13), substantially parallel to the axis of the pipe of the conic stop shoulder of the male portion or of the cone receiver of the female portion, includes one or more curved portions (24).
Patent CA-2509345-A1 (CA)
Title: Bacterial cell component-unresponsive model mouse
Inventor: AKIRA SHIZUO
IPC: C12N15/89
Filed: 2000-01-13
Abstract: A knockout mouse which is unresponsive to peptidoglycan, a lipoprotein/lipopeptide and the like, and is useful for elucidating the contribution of individual members of the TLR family to a signaling stimulated with bacterial cell components in vivo, in particular, the role of TLR2 and MyD88 in vivo. A bacterial cell component-unresponsive knockout mouse is generated by a process comprising the steps of: a targeting vector is constructed by replacing a whole or a part of a gene fragment of an exon region containing a cytoplasmic region of TLR2 or MyD88 gene and the like with a plasmid having a poly A signal and a marker gene; the targeting vector is introduced into an embryonic stem cell; the targeting embryonic stem cell having a homologously recombined TLR2 or MyD88 gene is microinjected into the blastocyst of a mouse and the blastocyst is put back into the uterus of a recipient mouse.
Patent CA-2510371-A1 (CA)
Inventor: CHAKLADER ASOKE CHANDRA DAS
IPC: C01B3/08
Filed: 2005-06-21
Abstract: The present invention provides a system for generating hydrogen gas in an aqueous solution based electrolytic or galvanic cell wherein the cathode is made form aluminum or an aluminum alloy. In a preferred arrangement the cell is a galvanic cell and cathode is made from aluminum or aluminum alloy and the anode is made from magnesium or magnesium alloy.
Patent CA-2511564-A1 (CA)
Title: Novel preadipocyte factor-1-like polypeptides
Inventor: MCALLISTER GREGG
IPC: C07K14/475
Filed: 2003-12-23
Abstract: The present invention discloses open reading frames (ORFs) in human genome encoding for novel Preadipocyte factor-1-like polypeptides, and reagents related thereto including variants, mutants and fragments of said polypeptides, as well as ligands and antagonists directed against them. The invention provides methods for identifying and making these molecules, for preparing pharmaceutical compositions containing them, and for using them in the diagnosis, prevention and treatment of diseases.
Patent CA-2512233-A1 (CA)
Title: Chime mp3 display
Inventor: RAPER WILLIAM C
IPC: G09F27/00
Filed: 2005-07-14
Abstract: A MP3 chime player and display device having a MP3 microcontroller unit being integrated with an in-store display.  The in-store display of the present invention has MP3 play selection buttons and associated selection insignia.  The microcontroller is in electronic communication with a reprogrammable digital storage device, an electronic port, speakers, volume controls, as well as buttons on the button board or in-store display.
Patent CA-2512641-A1 (CA)
Title: Apparatus and methods for drilling a wellbore using casing
Inventor: JACKSON RAYMOND H
IPC: E21B47/01
Filed: 2004-02-02
Abstract: Apparatus and methods for drilling with casing. In a first embodiment, a method for drilling with two concentric casing is disclosed. In a second embodiment, methods and apparatus for deflecting casing using a diverter apparatus are disclosed. In another embodiment, the apparatus comprises a motor operating system disposed in a motor system housing, a shaft operatively connected to the motor operating system, the shaft having a passageway, and a divert assembly disposed to direct fluid flow selectively to the motor operating system and the passageway in the shaft. In another aspect, methods and apparatus for directionally drilling a casing into the formation are disclosed. Methods and apparatus for measuring the trajectory of a wellbore while directionally drilling a casing into the formation are also described.
Patent CA-2514916-A1 (CA)
Title: Drive assembly for a reciprocating pump utilizing a linear actuator
Inventor: ST DENIS PERRY L
IPC: H01F7/16
Filed: 2005-07-28
Abstract: A drive assembly for a reciprocating pump includes a support structure with a linear actuator mounted on the support structure. The linear actuator has a stationary portion and a movable ram portion. At least one direction altering cable guide is mounted to the movable ram portion of the linear actuator. At least one cable is provided having a first end and a second end. The first end is anchored to one of the support structure or the stationary portion of the linear actuator. The second end is adapted for attachment to a polish rod of a reciprocating pump. As the movable ram portion moves, the cable and cable guide configuration provide a mechanical advantage which results in the polish rod reciprocally moving a multiple of the distance travelled by the movable ram portion of the linear actuator.
Patent CA-2515680-A1 (CA)
Title: Aminopropanediols acyles et analogues et leurs utilisations therapeutiques
Inventor: NAJIB JAMILA
IPC: C07C323/52
Filed: 2004-02-12
Abstract: La présente invention concerne d~ aminopropanediols acylés et leurs analogues azotés et sulfurés de formule générale (I), dans laquelle R, R1, R2, R3, G2 et G3 sont définis comme dans les revendications, des compositions pharmaceutiques les comprenant ainsi que leurs applications en thérapeutique, notamment pour le traitement de l'ischémie cérébrale.
Patent CA-2516219-A1 (CA)
Inventor: DAMNJANOVIC ALEKSANDAR
IPC: H04L47/30
Filed: 2004-02-17
Abstract: Various aspects of the invention provide for determining data rate for a reverse link communication by determining packets of data for transmission for a number of communication services, determining a data rate for transmission of the packets of data based on an arrangement of the packets of data in a queue allowing for meeting the transmission deadline for each of the packets of data. The base station determines whether available resources allow for allocation at the base station for transmission from the mobile station at the determined data rate and duration. The mobile station drops at least a packet of data of the packets of data in the queue to determine a new queue of packets of data. The new queue of the packets of data is used to determine a new data rate for communication on the reverse link.
Patent CA-2517990-A1 (CA)
Title: Methods and apparatus for handling and drilling with tubulars or casing
Inventor: THOMPSON GARY
IPC: E21B33/05
Filed: 2004-03-05
Abstract: The present invention provides a method and apparatus for handling tubulars and drilling with tubulars such as casing into a formation. In one aspect of the invention, the apparatus comprises a circulating head and a cementing head operatively connectible to a gripping member (220). The circulating head (3) is used to circulate drilling fluid while drilling with casing (400), and the cementing head (4) is used to cement the casing string within the formation at a desired depth. The present invention also relates to methods and apparatus for isolating a tensile load from a drilling apparatus rotated by a top drive.  In one aspect, the present invention provides a load isolator apparatus having an isolator body operatively connected to the top drive and a torque body at least partially disposed in the isolator body. In operation, the bearing assembly transfers the tensile load from the torque body to the isolator body.
Patent CA-2518539-A1 (CA)
Inventor: BIRKBECK PAUL
IPC: A61H33/00
Filed: 2005-09-08
Abstract: A bromine generator apparatus is provided for producing bromine from a bromide salt. The apparatus includes an electrical power unit, a housing, and first and second electrodes. The housing has inlet and outlet openings constructed and arranged for permitting the passage of water containing a bromide salt into the housing and water containing bromine out of the housing, respectively. The first and second electrodes electrically are connectable to the electrical power unit and have first and second contact regions, respectively, in the housing for contacting water passing through the housing and converting the bromine salt to the corresponding free bromine. The first and/or second contact regions are made of non-woven extruded graphite.
Patent CA-2518544-A1 (CA)
Title: Production of linear alkyl benzene
Inventor: GREAGER IVAN
IPC: C10G2/00
Filed: 2004-03-10
Abstract: This invention relates to a process for producing linear alkyl benzene and linear paraffins, the process including the steps of obtaining a hydrocarbon condensate containing olefins, paraffins and oxygenates from a low temperature Fischer-Tropsch reaction; a) fractionating a desired carbon number distribution from the hydrocarbon condensate to form a fractionated hydrocarbon condensate stream; b) extracting oxygenates from the fractionated hydrocarbon condensate stream from step a) to form a stream containing olefins and paraffins; c) alkylating the stream containing olefins and paraffins from step b) with benzene in the presence of a suitable alkylation catalyst; and d) recovering linear alkyl benzene and linear paraffin.
Patent CA-2518866-A1 (CA)
Title: Method of reducing acrylamide levels in food products and food intermediates and products and intermediates produced thereby
Inventor: NOVAK DOUGLAS J
IPC: A23L27/00
Filed: 2004-03-04
Abstract: The present invention relates to novel uses of cyclodextrins, to reduce acrylamide levels in food products and food intermediates after the food product or food intermediate has been cooked or otherwise treated to make it suitable for human or animal consumption, as well as to enhance the hypocholesterolemic benefit either individually or synergistically with other components.
Patent CA-2519554-A1 (CA)
Title: System and method for rapidly identifying pathogens, bacteria and abnormal cells
Inventor: WALKER FITZ JR
IPC: G01N15/14
Filed: 2004-03-25
Abstract: The present invention achieves rapid identification of pathogens, bacteria, cancer cells and other abnormal human and animal cells. In one embodiment, the system of the present invention comprises a first subsystem that obtains and processes images of specimens of pathogens, bacteria, and other abnormal cells, and a second subsystem that accepts the images, isolates the particular features of the image using advanced image segmentation, and then rapidly and accurately identifies the pathogens, bacteria and other abnormal cells by using a pattern recognition process wherein the segmented or isolated features of the original image are compared to known reference images.
Patent CA-2522108-A1 (CA)
Inventor: FAGAN RICHARD JOSEPH
IPC: C07K14/47
Filed: 2004-04-30
Abstract: This invention relates to a new family of secreted proteins, termed the SECFAM3 family, its family members including the novel human proteins INSP123, INSP124 and INSP125, herein identified as secreted proteins containing a von Willebrand Factor type C (vWFC) domain, and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
Patent CA-2522747-A1 (CA)
Title: Method of detecting native probnp with a monoclonal antibody binding to the amino acids 38-43
Inventor: SEIDEL CHRISTOPH
IPC: A61K39/00
Filed: 2004-05-12
Abstract: The present invention relates to antibodies specifically binding to native proBNP, a method for specific detection of native proBNP, a method of correlating the level of native proBNP to the diagnosis of heart failure, a kit for detection of native proBNP and to a hybridoma cell line producing an antibody to native proBNP.
Patent CA-2526222-A1 (CA)
Inventor: BARR PHILIP J
IPC: A61K31/351
Filed: 2004-05-17
Abstract: The present invention encompasses methods and compositions for the treatment and prevention of respiratory diseases associated with matrix metalloproteases. More specifically, the present invention relates to the treatment and prevention of respiratory diseases associated with matrix metalloproteases by inhalation of synthetic matrix metalloprotease inhibitors.  Exemplary respiratory diseases associated with matrix metalloproteases that may be treated by the methods of the invention include chronic obstructive pulmonary disease, emphysema, asthma, cystic fibrosis, and chronic bronchitis.  An exemplary synthetic matrix metalloprotease useful in the methods of the invention is ilomastat.
Patent CA-2527796-A1 (CA)
Title: Methods and apparatus for inventory allocation and pricing
Inventor: RAMAKRISHNAN VISHWAMITRA S
IPC: G06Q10/00
Filed: 2004-07-14
Abstract: The invention provides methods of, and systems for, optimizing the allocation of inventory to, and pricing of, goods sold by multiple retail sites, e.g., in a store, chain or other retail enterprise. Such a method includes generating a plurality of possible or "candidate" allocations of a given inventory among the multiple retail sites. That inventory can be, for example, a supply of the same or like goods at a distribution center that serves the retail sites. Each candidate allocation comprises an assignment of a respective share of that inventory to each of the sites. For each of the candidate allocations, an optimal price of the goods at each of the retail sites is estimated. The optimal price is one that will return an optimal gross margin to the respective site, given its assignment of the respective share of the inventory for the particular candidate allocation. For each of the candidate allocations, a sum is determined of the optimal gross margins across all the retail sites. From substantially all possible allocations, the candidate allocation that results in a largest total optimal gross margin is efficiently chosen.
Patent CA-2530569-A1 (CA)
Title: Curable phase change ink composition
Inventor: WAGNER CHRIS A
IPC: B41J2/01
Filed: 2005-12-15
Abstract: Ink compositions that comprise one or more radiation curable oil soluble components and one or more thermal solvents are provided, as well as methods of preparing such ink compositions and methods of using such ink compositions are provided.
Patent CA-2531606-A1 (CA)
Inventor: OGIWARA YASUYUKI
IPC: D21G9/00
Filed: 2005-12-23
Abstract: The present invention relates to a leader cloth for pulling a new belt onto a paper machine and laying the same onto rolls when replacing a cloth or belt for paper machine.    The configuration of the leader cloth according to the present invention is formed by an apex portion, a base portion, and right and left side edge portions connecting between each end portion of the base portion and the apex portion, and has a chevron-like shape substantially symmetrical with respect to a perpendicular line dropped from the center of the apex portion to the base portion as the axis of symmetry, and the left side edge portion is a curved line residing between two curved lines expressed by the following quadratic equation (1) and the following cubic equation (2), with respect to the width direction x and the longitudinal direction y ; and the right side edge portion is a curved line substantially symmetrical with respect to the left side edge portion: y= (b/a2) x2 ...... (1) y= (b/a3) x3 ...... (2) (In formula (1) and (2), "a" is a distance in width direction between the end of base portion and the end of apex portion "b" is a distance between the base portion and the apex portion). According to the present invention, the tensile force is applied to the leader cloth entirely. Since there is no portion with the tensile force unapplied, such troubles can be prevented as belt sticking during pulling operation due to hanging down or ridge.
Patent CA-2531722-A1 (CA)
Title: Multi-reel slot machine with selectable reel play
Inventor: DALY TERENCE G
IPC: A63F13/00
Filed: 2004-06-23
Abstract: A reel spinning gaming device (10) includes a plurality of selectable reels (20) each having game symbols (30) located thereon, a selection system (40), an actuating system (50), and a prize controller (60). Each reel displays an outcome symbol (30) after having been spun. The number of selectable reels included in the gaming device is larger than that utilized for an individual game. The actuating system then spins the initial active reels (70), after which the prize controller determines whether or not a prize is to be awarded dependent upon the combination of the outcome symbols from the initial active reels. Specifically, the active reels for the subsequent consecutive game include the newly substituted active reel and the remaining active reels from the previous game. This process is repeated until all of the games purchased by the player have been exhausted.
Patent CA-2536502-A1 (CA)
Inventor: NEBLE RHYAN
IPC: G06F12/16
Filed: 2004-08-27
Abstract: Methods, apparatuses, and computer-readable media for distributing digital content. One embodiment comprises an apparatus comprising: a device (100) communications bus; coupled to the device communications bus (150), a bi-directional communications controller (110) capable of communicatively interfacing with a computer (710); coupled to the device communications bus (150), an integrated processor (130) capable of executing (270) computer-executable instructions; and coupled to the integrated processor (130), a storage module (140) capable of storing computer-executable instructions.
Patent CA-2545735-A1 (CA)
Title: Wear resistant polymers
Inventor: CASEY PHIL
IPC: C08K3/36
Filed: 2003-10-10
Abstract: A method of improving the wear resistance of a polymer is disclosed comprising the steps of evenly dispersing an ultrafine inorganic particulate material in the polymer at a loading rate of 0.01 to 20wt% of the total weight of the particulate polymer composite. The mixing or dispersing is preferably carried out under sub-atmospheric pressure conditions to ensure little or no bubbles form in the mixture prior to curing.