baber/WOPTO huggingface dataset:
Patent AU-596954-B2 (AU)
Title: Wound healing agents
Inventor: KNIGHTON DAVID R
IPC: A61K35/14
Filed: 1985-11-08
Granted: 1990-05-24
Abstract: A composition comprising a first substance which causes direct growth of capillary endothelium and a second substance which is mitogenic for cells selected from the group consisting of fibroblast cells, capillary endothelial cells and epithelial cells is useful for preparing a medicament to be applied to wounds for the purpose of forming granulation tissue in the wounds or may be used for cosmetic purposes.
Patent AU-728911-B2 (AU)
Title: Mutants of the LAG-3 proteins, products for the expression of these mutants and use
Inventor: TAYAR NABIL EL
IPC: A61K45/00
Filed: 1997-11-25
Granted: 2001-01-18
Abstract: The invention concerns a purified polypeptide corresponding to a mutated form of the soluble LAG-3 protein or of one of its fragments comprising the extra-cellular domain D1 and D2.
Patent AU-693772-B2 (AU)
Title: Immunoassay
Inventor: TRELOAR PAUL HOWARD
IPC: G01N27/40
Filed: 1993-12-03
Granted: 1998-07-09
Abstract: Electrochemical immunoassay methods are disclosed. In one method, a membrane is provided between the sample and the detecting electrode. The membrane is such that it will allow passage therethrough of unbound labelled analyte (but not its complex with antibody). The unbound labelled analyte, which is electrochemically active, may then be detected at the electrode. In a further method, the electrochemical immunoassay uses a labelled analyte which is both fluorescent and electrochemically active. This allows optimisation of the electrochemical immunoassay.
Patent AU-675102-B2 (AU)
Title: Atovaquone pharmaceutical compositions
Inventor: DEARN ALAN ROY
IPC: A61P33/02
Filed: 1993-12-23
Granted: 1997-01-23
Abstract: The invention relates to a process for the production of microfluidized particles of atovaquone having improved bioavailability.
Patent AU-727036-B2 (AU)
Title: Alphavirus RNA replicon systems
Inventor: JOHNSTON ROBERT E
IPC: A61K39/00
Filed: 1996-05-21
Granted: 2000-11-30
Abstract: The present invention provides a helper cell for expressing an infectious, replication defective, alphavirus particle in an alphavirus-permissive cell. The helper cell includes (a) a first helper RNA encoding (i) at least one alphavirus structural protein, and (ii) not encoding at least one alphavirus structural protein; and (b) a second helper RNA separate from the first helper RNA, the second helper RNA (i) not encoding the alphavirus structural protein encoded by the first helper RNA, and (ii) encoding the at least alphavirus one structural protein not encoded by the first helper RNA, such that all of the alphavirus structural proteins assemble together into alphavirus particles in the cell. Preferably, the helper cell also includes a replicon RNA encoding an alphavirus packaging sequence and an inserted heterogeneous RNA.
Patent AU-635333-B2 (AU)
Title: Novel aniline derivatives and fungicides containing them
IPC: C07C69/738
Filed: 1990-09-27
Granted: 1993-03-18
Abstract: The invention relates to aniline derivatives of the formula 
<IMAGE>
 in which 
 
  R represents hydrogen, halogen, cyano, nitro, alkyl, cycloalkyl, alkenyl, alkoxy, haloalkyl, haloalkoxy, optionally substituted phenyl, phenoxy, benzyl or benzyloxy, 
  m represents an integer from 1 to 5 or the group 
<IMAGE>
  alpha -naphthyl or  beta -naphthyl and 
  X represents hydrogen, alkyl or cycloalkyl, 
 their phytophysiologically acceptable acid addition salts and metal complex compounds, and to their use for controlling fungi.
Patent AU-735684-B2 (AU)
Title: Method of treating dry eye disease with purinergic receptor agonists
Inventor: YERXA BENJAMIN R
IPC: A61K47/02
Filed: 1998-02-06
Granted: 2001-07-12
Abstract: A method and preparation for the stimulation of tear secretion in a subject in need of such treatment is disclosed. The method comprises administering to the ocular surfaces of the subject a purinergic receptor agonist such as uridine 5′-triphosphate (UTP), dinucleotides, cytidine 5′-triphosphate (CTP), adenosine 5′-triphosphate (ATP), or their therapeutically useful analogs and derivatives, in an amount effective to stimulate tear fluid secretion and enhance drainage of the lacrimal system. Pharmaceutical formulations and methods of making the same are also disclosed. Methods of administering the same would include: topical administration via a liquid, gel, cream, or as part of a contact lens or selective release membrane; or systemic administration via nasal drops or spray, inhalation by nebulizer or other device, oral form (liquid or pill), injectable, intra-operative instillation or suppository form.
Patent AU-590333-B2 (AU)
Title: Reducing viscosity of high viscosity materials
Inventor: KLAILA WILLIAM J
IPC: B05C11/10
Filed: 1986-08-27
Granted: 1989-11-02
Abstract: A method and apparatus for reducing the viscosity of high viscosity material within a container. An electromagnetic enery source is mounted within a housing which is provided with a fixture that is configured to interconnect with the container of high viscosity material. A waveguide and a deflector are provided for directing the electromagnetic energy from the source to the container for heating the high viscosity material therein and reducing its viscosity.
Patent AU-658808-B2 (AU)
Title: Endless belt for dewatering press
Inventor: WATANABE ATSUO
IPC: B30B9/24
Filed: 1994-06-01
Granted: 1995-04-27
Abstract: An endless belt in which a fibrous material (1) is dispersed in a substantially uniform manner all over an endless elastic body layer (30a) is provided. A non-woven tape (1) is impregnated with a polyurethane elastomer material liquid (5) and wound and layered on a supporting belt (11), and then, after curing the polyurethane elastomer material liquid to form an elastic body (30a), it is removed from supporting belt (11). <IMAGE>
Patent AU-639949-B2 (AU)
Title: Injection compression molding method for compact discs or the like
IPC: G11B7/26
Filed: 1990-10-29
Granted: 1993-08-12
Abstract: An injection compression molding method for compact discs or the like, comprising the step of changing the clamping pressure or compression pressure, after the internal cavity pressure in the mold after injection has reached its peak, stepwise or continuously as the cooling proceeds, thereby making the applied pressure per unit area with respect to the effective pressure range constant. In a compact disc formed by this method, the residual stress after cooling is uniform, so that its optical properties are improved substantially.
Patent AU-604225-B2 (AU)
Title: Disposable diaper having wide tapered fastening tapes
Inventor: BURKHARD HAROLD RICHARD
IPC: A61F13/15
Filed: 1987-01-20
Granted: 1990-12-13
Abstract: A disposable diaper having elasticized leg openings and improved fastening tapes which have a user's end that is wide at the longitudinal sides of the diaper and that is tapered to a more narrow width at its distal end. The wide user's end of the fastening tapes tensions and secures more of the overlapping waist portions of the diaper so that a good fit about the legs and waist is maintained. Tapering of the user's end of the tapes increases wearing comfort and makes them easier to handle and apply.
Patent AU-535692-B2 (AU)
Title: Defibering unconventional material in vortical cir- culation pulper
Inventor: DANFORTH DONALD W
IPC: D21B1/34
Filed: 1981-02-27
Granted: 1984-03-29
Abstract: A vortical circulation type pulper (20) has a vaned rotor (27) and an annularbladed and channeled stator (26) mounted in a side (23), or bottom (22) wall, the rotor (27) and annular stator (26) having a truncated conical interface (35) with the small end (36) receiving stock (25) for passage through the interface (35) to the large end (39) and thence for discharge or recirculation. Rotor/stator clearance, at rest, is about 0.38 mm.The stator (26) is provided with an annular, pattern of alternate, acquisition valleys (61) and bladed and channeled peaks (59), each peak (59) having an acquisition edge (69) in the path of the outer bladed edge (53) of the rotor vanes (48) so that the stock (25) is reduced by the scissors-like contact of rotor blade edge (53) and stator peak edge (69) until sufficiently defibred to enter the truncated conical, bladed and channeled rotor/stator interface (35) for recirculation or discharge.
Patent AU-640739-B2 (AU)
Title: Peptides which inhibit blood coagulation, processes for the preparation thereof and the use thereof
IPC: A61K38/00
Filed: 1991-02-21
Granted: 1993-09-02
Abstract: Peptides of the formula I  A1-A2-A3-A4-A5-A6-A7-A8-A9-A10-A11-A12-A13-A14-A15  in which   A1 is hydrogen, cysteine, acetylcysteine, one or two alkyl groups with 1-4 C atoms, an acyl group with 2-10 C atoms, an acyl group with 2-10 C atoms and another carboxyl group, or a protective group customary in peptide chemistry,   A2 is a bond, Asn, Asp, Gln or Glu,   A3 is a bond, Gly or Ala,   A4 is Glu or Asp,   A5 is Phe, Tyr, Trp, Pgl (phenylglycine) or Nal (naphthylalanine),   A6 is Glu or Asp,   A7 is Glu, Asp, Pro or Ala,   A8 is Ile, Leu, Val, Nle or Phe,   A9 is Pro or Hyp,   A10 is Glu or Asp,   A11 is Glu or Asp, A12 is Phe(SO3H) or Phe(PO3H2) (preferably in the p position) or Pgl(SO3H) or Pgl(PO3H2) (preferably in the p position),   A13 is a bond, Leu, Ile, Val or Ala,   A14 is a bond, Gln, Asn, Glu, Asp or Cys and A15 is Cys, Cys-amide, an OH group of the alpha-carboxyl group, free or esterified with a lower alcohol with up to 4 C atoms, which can also be in the form of the carboxamide functionality whose hydrogens can optionally be replaced by alkyl groups with up to 4 C atoms, and a process for the preparation thereof are described. These peptides inhibit blood coagulation and can be used as anticoagulants.
Patent AU-683083-B2 (AU)
Title: Profiles, die and method for producing same
Inventor: CHIN DOUGLAS H
IPC: B29C48/12
Filed: 1994-08-11
Granted: 1997-10-30
Abstract: A method is provided for triple extrusion of a foam material, a coating and one or more flexible flanges attached to the coating or foam material. All three materials are coextruded through a common die and are useful for forming window sashes.
Patent AU-651586-B2 (AU)
Title: Biological system for degrading nitroaromatics in water and soils
Inventor: CRAWFORD DONALD L
IPC: C09K101/00
Filed: 1991-04-09
Granted: 1994-07-28
Abstract: Novel methods for biodegrading nitroaromatic compounds present as contaminants in soil or water using microorganisms are disclosed. Water is treatable directly; dry soil is first converted into a fluid medium by addition of water. The preferred method comprises two stages, each employing microorganisms: a fermentative stage, followed by an anaerobic stage. The fermentative stage is rapid, wherein an inoculum of aerobic and/or facultative microorganisms ferments a carbohydrate added to the fluid medium, exhausting the oxygen in the fluid medium and thereby inhibiting oxidative polymerization of amino by-products of the nitroaromatics. In the subsequent anaerobic stage, an inoculum of a mixed population of anaerobic microorganisms completes the mineralization of the contaminant nitroaromatics, using the remaining carbohydrate as a carbon and energy source. Preferably, the carbohydrate is a starch and the aerobic and/or facultative microorganisms are amylolytic, which cleave the starch at a moderate rate throughout both stages, ensuring a sustained supply of metabolizable carbohydrate. The microorganisms are preferably selected to be resistant to the types and concentrations of nitroaromatics present as contaminants.
Patent AU-698699-B2 (AU)
Title: Esters of substituted-hydroxyacetyl piperazine phenyl oxazolidinones
Inventor: BRICKNER STEVEN J
IPC: C07F9/6558
Filed: 1994-09-27
Granted: 1998-11-05
Abstract: PCT No. PCT/US94/10582 Sec. 371 Date May 9, 1996 Sec. 102(e) Date May 9, 1996 PCT Filed Sep. 27, 1994 PCT Pub. No. WO95/14684 PCT Pub. Date Jun. 1, 1995A compound of structural Formula (I) or pharmaceutically acceptable salts thereof wherein: R is -C(O)-R1, -PO3= or -P(O)(OH)2; R1 is C1-6alkyl, -N(R4)2, C1-6alkyl-N(R4)2, -phenyl-N(R4)2, -phenyl-NHC(O)CH2NH2, -C2H4-morpholinyl, pyridinyl, C1-6alkyl-OH, C1-6alkyl-OCH3, C1-6alkyl C(O)CH3, -O-C1-6alkyl-OCH3, C0-3alkyl-piperazinyl (optionally substituted with C1-3alkyl), imidazolyl, C1-6alkyl-COOH, -C(CH2OH)2CH3; R2 and R3 are independently selected from hydrogen or F except at least one of R2 or R3 is F; R4 are independently selected from hydrogen or C1-6alkyl. The compounds are water soluble and are useful antimicrobial agents, effective against a number of human veterinary pathogens, including multiply-resistant staphylococci, enterococci and streptococci, as well as anerobic organisms such as bacteroides and clostridia species, and acid-fast organisms such as Mycobacterium tuberculosis.
Patent AU-613596-B2 (AU)
Title: Improved process for transforming plant protoplasts
Inventor: NEGRUTIU IOAN
IPC: C12N15/07
Filed: 1987-12-04
Granted: 1991-08-08
Abstract: The method makes use of simple, purely chemical procedures and entails the genetic material being transferred into the plant cell directly without using a natural system which is infectious for plants, such as a plant bacterium or plant virus, and without transfer by insects or phytopathogenic fungi, but by incubating together the DNA to be transformed and the plant protoplasts in a suitable incubation medium. It is possible in this way to transfer genes very straightforwardly and efficiently into plant material, resulting in plants with improved properties. <IMAGE>
Patent AU-548962-B2 (AU)
Title: Detergent powders of improved solubility
Inventor: RAPISARDA ANTHONY ARTHUR
IPC: C11D3/395
Filed: 1982-05-31
Granted: 1986-01-09
Abstract: The present invention relates to a process for making a powder detergent of improved solubility. The process comprises mixing about 10-60% builder, about 0.6-6% surfactant, about 20-50% alkaline agent and 0-70% filler, about 10-30% of solid alkali metal silicate and a bleaching agent selected from the group of active chlorine or oxygen containing compounds providing about 0.4-1.5% available chlorine or the equivalent thereof in such order that the addition of the alkali metal silicate is made after or in combination with the alkaline agent, the pH of the resulting finished product being 10.4 or greater at about a 0.25% product use concentration.
Patent AU-550610-B2 (AU)
Title: Article grading apparatus
Inventor: WRIGHT RAYMOND GRENVILLE WHITE
IPC: A23N15/00
Filed: 1982-06-18
Granted: 1986-03-27
Abstract: Potatoes which are to be graded according to their size prior to further processing, for example in the manufacture of a snack food product, are deposited in a hopper 16 at the lower end of an upwardly inclined walking beam conveyor 18. Pockets 35, 37 formed in the conveyor 18 pick up potatoes from the hopper 16 and convey them along the conveyor by transferring each potato from pocket to pocket. Any potatoes whose dimensions are greater than those of the pockets 35, 37 are either not picked up or fall out of the pockets under gravity as the conveyor 18 is operated and drop back into the hopper 16. Periodically, a base wall 17 of the hopper 16 is opened to discharge the accumulated large-size potatoes therefrom.
Patent AU-726974-B2 (AU)
Title: Leucocyte-removing filter medium
Inventor: FUKUDA TATSUYA
IPC: B01D39/16
Filed: 1998-08-25
Granted: 2000-11-30
Abstract: A leukocyte-removing filter medium for removing leukocytes from a leukocyte-containing fluid, wherein said filter medium has, at least on its surface, hydrophilic basic groups containing at least one nonionic hydrophilic portion and at least one basic portion, in which said hydrophilic portion(s) is located nearer to the end of the hydrophilic basic group than said basic portion(s) is. <IMAGE>
Patent AU-646520-B2 (AU)
Title: Phospholipid analogue vesicle with a succinimidyl moiety
Inventor: SULLIVAN SEAN M
IPC: A61K47/22
Filed: 1991-10-09
Granted: 1994-02-24
Abstract: Delivery vehicle formulations comprising active agents encapsulated within microparticles which include a succinimidyl moiety extending externally from a lipid molecule therein are capable of the cytoplasmic or nuclear cell delivery of intact encapsulated active agents.
Patent AU-665934-B2 (AU)
Title: A diagnostic assay for lyme disease
Inventor: CALLISTER STEVEN M
IPC: C12Q1/06
Filed: 1991-10-31
Granted: 1996-01-25
Abstract: A method of performing an assay to determine whether a patient has been exposed to or infected by Borrelia burgdorferi is disclosed which comprises collecting serum from the patient; preparing a sample mixture comprising a portion of the patient's serum and an inoculum of viable Borrelia burgdorferi organisms; incubating the sample mixture; determining the number of viable organisms remaining in the sample mixture after incubation; and comparing the number with the quantity of viable organisms remaining in a control. An assay kit is also disclosed which is useful for determining whether a patient has been exposed to or infected by Borrelia burgdorferi. The kit contains reagents necessary to practice the assay method disclosed herein. In its broadest form, the kit comprises an inoculum of viable borrelia burgdorferi organisms. The kit can also contain an aliquot of normal serum, an aliquot of BSK medium and/or an aliquot of complement. Other reagents, tubes and other materials can also be included in the kits.
Patent AU-555243-B2 (AU)
Title: Heat sensitive cable
Inventor: DAVIS BAYARD C
IPC: G01K7/22
Filed: 1982-10-15
Granted: 1986-09-18
Abstract: A heat sensitive cable operable over a temperature range of between approximately -30°C and 900°C. The cable Includes a tubular metallic sheath which is substantially temperature resistant and moisture impervious. It also includes a mass of compacted insulation material filling the sheath and having an insulation resistance variable with temperature in the range of between approximately 100 and 50,000 ohms. The cable further Includes at least one thermoelectric conductor positioned within the insulation material filling the sheath. A method of manufacturing the cable includes the step of preparing the insulation material and advancing the thermoelectric conductor through a given region. It also includes the step of advancing a strip of flat metal material past apparatus for forming and welding a tubular sheath surrounding the given region. The method further includes the step of concurrently depositing the insulation material within the tubular sheath for enclosure and advancing the sheath, insulation material and conductor through apparatus for reducing the diameter of the sheath and applying tension to the conductor. With these steps, the insulation material is compacted and the conductor is positioned within the sheath.
Patent AU-664980-B2 (AU)
Title: An improved self-tuning controller
Inventor: HANSEN PETER D
IPC: G05B13/02
Filed: 1991-10-28
Granted: 1995-12-14
Abstract: An apparatus and method for automatically adjusting the control parameters of a self tuning controller used to regulate a process having a measured process variable signal. Using the measured process variable signal, an error signal representing a closed-loop response of the process to an upset condition is generated. Local extrema of the error signal is measured and three successive amplitude values are selected to produce measured decay and overshoot characteristics of the error signal. The three successive amplitude values are selected such that the measured decay characteristic is greater than the overshoot characteristic. Based on the measured decay and overshoot characteristics at least one of the control parameters of the controller is automatically adjusted to improve the difference between one of the measured characteristics and a target characteristic.
Patent AU-654990-B2 (AU)
Title: Novel platinum(II) complex and processes for preparing the same
Inventor: KIM DAE-KEE
IPC: C07D317/28
Filed: 1991-12-30
Granted: 1994-12-01
Abstract: Disclosed herein are novel platinum(II) complexes having a potent anti-tumor activity which are represented by the formula (1),    <IMAGE>  (1)   <IMAGE>  (a)   <IMAGE>  (b)  wherein R1 and R2, which may be the same or different, are a hydrogen atom or a C1-4 alkyl group, respectively, or jointly form a cycloalkane group together with the carbon atom attached thereto; two Xs jointly form a group represented by formula (a) or (b) wherein, R3 is a hydrogen atom or a methyl group; R4 and R5, which may be the same or different, are a hydrogen atom or a C1-4 alkyl group, respectively, or jointly form a cyclobutane together with the carbon thereto; and the absolute configurations at the respective chiral centers in the 4,5-bis(aminomethyl)-1,3-dioxolane moiety are (4R,5R) or (4S,5S); processes for the preparing the same; and their use for treating animal or human cancer. Further, disclosed herein are novel intermediates useful for the preparation of the platinum(II) complexes and processes for preparing said intermediates.
Patent BG-61202-B2 (BG)
Inventor: MAKINO TADASHI
IPC: C07D401/12
Filed: 1994-02-14
Abstract: 1. Стабилизиран фармацевтичен състав, който съдържа киселинно неустойчиво съединение с формула, в която r1 е водород, алкил, халоген, циано, карбокси, карбоалкокси, карбоалкоксиалкил, карбамоил, карбамоилалкил, хидрокси, алкокси, хидроксиалкил, трифлуорометил, ацил, карбамоилокси, нитро, ацилокси, арил, арилокси, алкилтио или алкилсулфинил, r2 е водород, алкил, ацил, карбоалкокси, карбамоил, алкилкарбамоил, диалкилкарбамоил, алкилкарбонилметил, алкоксикарбонилметил или алкилсулфонил, r3 и r5 саеднакви или различни и всеки представлява водород, алкил, алкокси или алкоксиалкокси, r4 е водород,алкил, алкокси, който може евентуално да бъде флуориран, или алкоксиалкокси, а м е цяло число от 0 до 4, или негова фармацевтично приемлива сол, и основна неорганична магнезиева и/или основна неорганична калциева сол.
Patent DE-1801842-B2 (DE)
Title: Automatic removal of runners in injection moulding
IPC: B29C45/17
Filed: 1968-10-08
Abstract: Apparatus for the automatic extraction of injection runners in capillary moulding so that the press may be completely automated, comprising means for grasping the runners consisting of gripping arms pivoting a two axes, means for supporting the gripping arms consisting of a rotary and a sliding support with spring operating against stops, and motors for operating the device. The apparatus enables completely automatic operation of injection moulds to be achieved by providing extraction of the runners.
Patent DE-1962780-B2 (DE)
Title: Window thrust limiting mechanism - has stop piece in housing with flange hole for rosette screw
IPC: E05C9/02
Filed: 1969-12-15
Abstract: A covering rail, setting rod with locking lugs passing through slits in the rail, and gear housing with drive pinion, are incorporated in an edge gear forming a structural unit in a groove in a window, or door wing, with thrust limitation facility. The limiting device (12) has a limiter (18), with stop faces (23), fixed on the polygonal pin (33). This coacts with a flat accommodating a housing (13) with counters tops (24). The housing has a fixing flange (16), overlapped by the rosette (31), with a hole for one of its fixing screws (36). It is sited between the rosette and the gear housing (4), and pref. has two fixing flanges on opposite sides. Optionally, the limiting device can be used in different ways without alteration of the structural unit.