baber/WOPTO huggingface dataset:
Patent NZ-228710-A (NZ)
Title: Modified "echistatin" and anti-clotting pharmaceutical composition
Inventor: FRIEDMAN PAUL A
IPC: C12N15/00
Filed: 1989-04-12
Abstract: A platelet aggregation inhibiting polypeptide having the following amino acid sequence:  X-Cys-R-R-R-Arg-Gly-Asp-R-R-R-R-R-Cys-Y where X is H or at least one amino acid; Y is OH or at least one amino acid; and each R, either the same or different, is any amino acid. Genetically engineered genes for the polypeptides are described and expressed as a fusion protein using the pJC264 expression vector in E. coli. Synthetic polypeptides and methods of synthesis are also described.
Patent NZ-230911-A (NZ)
Title: Lactobacillus helveticus agc1 and its use in ripening cheddar style cheeses
Inventor: CALLANAIN TADGH
IPC: A23C19/032
Filed: 1989-10-05
Abstract: The invention relates to Lactobacillus helveticus AGC1, a sample of which has been deposited on 29 September 1988 at The National Collections Of Industrial And Marine Bacteria Limited under the accession number NCIB 40051, or a mutant or derivative thereof. This strain is useful as part of a starter culture addition to cheese milk, for accelerated ripening of cheddar style cheeses.
Patent NZ-242084-A (NZ)
Title: Polyethylene glycol protein conjugates.
Inventor: HAKIMI JOHN
IPC: A61K47/48
Filed: 1992-03-23
Abstract: The present invention relates to physiologically active, substantially non-immunogenic water soluble polyethylene glycol protein conjugates having at least part of the biological activity of the protein which forms the conjugate, without exhibiting the same disadvantageous immunogenic responses thereof.
Patent NZ-247836-A (NZ)
Title: Countering the adverse effects of aging on mammalian cells using 6-(substituted amino) purine cytokinins
Inventor: RATTAN SURESH INDER SINGH
IPC: A61Q19/08
Filed: 1991-05-21
Abstract: Ameliorating the adverse effects of ageing on mammalian cells comprises; contacting the cells with a compsn. that contains a 6-(substd. amino) purine cytokinin in a concn. sufficient to ameliorate the adverse effects of ageing. The rate of development of characteristics of ageing is reversed or slowed, and the growth rate and total proliferative capacity of the cells, after contact with the compsn., is the same as prior to contact. Pref. the cytokinin is of formula (I). In (I) R1 = furfuryl, phenyl, benzyl, 4-6C n-alkyl, cyclohexylmethyl, (3-hydroxymethyl-3-methyl)allyl or 3,3-dimethylallyl. (I) is most esp. furfuryladenine (kinetin).
Patent NZ-250682-A (NZ)
Title: Heterotricyclyloxoalkyl substituted piperidine, piperazine and 4-benzylpiperidine derivatives, their preparation and pharmaceutical compositions
Inventor: GOTO GIICHI
IPC: C07D413/06
Filed: 1994-01-14
Abstract: A novel compound of the formula: <CHEM> wherein Ar represents an optionally substituted tricyclic condensed benzene ring group which includes at least one heterocyclic ring as a component ring; n represents an integer from 2 to 10; R<1> represents H or an optionally substituted hydrocarbon group, which may be different from one another in the repetition of n; and Y represents an optionally substituted 4-piperidinyl, 1-piperazinyl or 4-benzyl-1-piperidinyl group, or a salt thereof, inhibiting excellent cholinesterase inhibitory activity and monoamine reuptake inhibitory activity, thus being useful as therapeutic and/or prophylactic medicaments of senile dementia.
Patent NZ-253542-A (NZ)
Title: Bicyclic quaternary-n-containing phosphonate derivatives and medicaments
Inventor: EBETINO FRANK H
IPC: C07F/
Filed: 1993-05-27
Abstract: The present invention relates to a quaternary nitrogen-containing, saturated or unsaturated monocyclic and bicyclic ring containing phosphonate and the pharmaceutically-acceptable salts and esters thereof, having structure (I). The present invention further relates to pharmaceutical compositions containing a safe and effective amount of a compound of the present invention, and pharmaceutically-acceptable excipients. Finally, the present invention relates to methods for treating or preventing pathological conditions characterized by abnormal calcium and phosphate metabolism in humans or other mammals. This method comprises administering to a human or other mammal in need of such treatment of a safe and effective amount of a compound or composition of the present invention.
Patent NZ-263905-A (NZ)
Title: Switching system accommodating telemetry interface units
Inventor: GARLAND STUART MANDEL
IPC: H04M11/00
Filed: 1994-02-16
Abstract: A communication switching system, in addition to normal services i.e., voice, FAX, data, etc., provides secure bi-directional communication between the facilities of a utility and specialized voice and/or data CPE which are served by an on-premises Telemetry Interface Unit. A Central Office Service Unit (COSU), which is connected to a switching system by Utility Telemetry Trunks (UTT), is employed as an interface between utilities and one or more communication switching systems. The COSU provides detailed calling instructions and data which define the services to be rendered by the switching system. The detailed instructions serve to: define the source and character of the signals to be used to alert the TIU; sub-addresses of CPE served by a TIU; conduct of line supervision; permitted supervisory state of a called line at time of call to a TIU; broadcast of messages, etc.
Patent NZ-295668-A (NZ)
Title: 3-(hetero)arylmethylene-2-oxo-7-azaindole derivatives
Inventor: BUZZETTI FRANCO
IPC: C07D471/04
Filed: 1995-10-30
Abstract: PCT No. PCT/EP95/04247 Sec. 371 Date Jul. 9, 1996 Sec. 102(e) Date Jul. 9, 1996 PCT Filed Oct. 30, 1995 PCT Pub. No. WO96/16964 PCT Pub. Date Jun. 6, 1996The present invention relates to compound of formula (I)    <IMAGE>  (I)  wherein A is benzene, naphthalene, 5,6,7,8,-tetrahydronaphthalene, quinoline, isoquinoline, indole or 7-azaindole; R1 is -H, -CN, -SO3R4-, -SO2NHR5,   <IMAGE>    -COOR6, -CONHCH2(CHOH)nCH2OH,   <IMAGE>    -NR7R8, -N(CH2CH2OH)2, -NHCH2(CHOH)nCH2OH, -NHCONH2, -NH-C(NH2)=NH, -NHCO(CHOH)nCH2OH,   <IMAGE>    -NHSO2R9, -OR10, -OCH2(CHOH)nCH2OH, -OOC(CHOH)nCH2OH, -OPO(OH)2, -CH2NH2, -C(NH2)=NH, -CH2NHC(NH2)=NH,   <IMAGE>    -CH2OH, -CH2OOC(CHOH)nCH2OH, -CH2OPO(OH)2 or -PO(OH)2; R2 is C1-C6 alkyl, halogen, or hydroxy; R3 is -H or C1-C6 alkyl; R4 is -H, C1-C6 alkyl or -CH2(CHOH)nCH2OH; R5 is -H, C1-C6 alkyl, -CH2(CHOH)nCH2OH or -(CH2)mNMe2; R6 is -H, C1-C6 alkyl or -CH2(CHOH)nCH2OH; each of R7 and R8 independently is -H or C1-C6 alkyl; R9 is methyl or tolyl; R10 is -H, C1-C6 alkyl, or C2-C6 alkanoyl; Z is >CH2, >O, >NH, or >NCH2CH2OH; n is zero or 1; m is 2 or 3; p is 1, 2 or 3; q is zero, 1 or 2; and the pharmaceutically acceptable salt thereof, for use as tyrosine kinase inhibitors.
Patent NZ-321370-A (NZ)
Title: Polymorphic forms of a growth hormone secretagogue
Inventor: DRAPER JEROME P
IPC: C07K5/062
Filed: 1996-10-23
Abstract: Disclosed are polymorphic forms of the compound N-[1(R)-[(1,2-dihydro-1-methanesulfonylspiro[3H-indole-3,4'-piperdin]-1'-yl)carbonyl]-2-(phenylmethyloxy)ethyl]-2-amino-2-methylpropanamide methanesulfonate which is a growth hormone secretagogue that is useful in food animals to promote their growth thereby rendering the production of edible meat products more efficient, and in humans, to treat physiological or medical conditions characterized by a deficiency in growth hormone secretion, and to treat medical conditions which are improved by the anabolic effects of growth hormone. The instant polymorphic forms have advantages over the other known forms of N-[1(R)-[(1,2-dihydro-1-methanesulfonylspiro[3H-indole-3,4'-piperdin]-1'-yl)carbonyl]-2-(phenylmethyloxy)-ethyl]-2-amino-2-methylpropanamide methanesulfonate in terms of thermodynamic stability and suitability for inclusion in pharmaceutical formulations. Also disclosed are processes for preparing these polymorphic forms, pharmaceutical formulations comprising these polymorphic forms as active ingredients and the use of the polymorphic form of the compound and their formulations in the treatment of certain disorders.
Patent NZ-330079-A (NZ)
Title: Milk box and milk unit moveable forwardly and backwardly about one or more hinges
Inventor: VAN DEN BERG KAREL
IPC: A01J5/04
Filed: 1997-07-01
Abstract: n implement comprising a milk box 1 and a milk unit, for automatic connecting of teat cups 25 of the unit to the teats of a cow, is claimed.  The unit  is moveable in a horizontal direction forwardly and backwardly about one or more hinges extending near the upper part of the cow.  One of the hinges is located above the milk box.  The implement may include a robot arm construction 3 with a supporting unit 4 moveable along at least one or more rail constructions 5, 6 in the longitudinal direction of the milk box 1.  Figure 1 shows a side view and Figure 2 shows a front view of the implement.  Divisional filed as 335913
Patent NZ-330830-A (NZ)
Title: Closure flap, on hinged panel of box, with tab that folds or deforms as panel is closed
Inventor: BLACKMAN STEPHEN BRUCE
IPC: B65D5/30
Filed: 1998-06-29
Abstract: losure flap 103 is on a hinged panel of a storage box (the views being respectively front sectional elevation and plan for the flap closed with respect to the box).  Tab 105 on flap 103 interacts with a side 101/102 of the box such that during initial closure it will fold and/or deform providing  continued resistance against the side 101/102 during further closure.
Patent NZ-500646-A (NZ)
Title: Disposable infant feeding bottle with nipple occupying either a stable collapsed or extended condition
Inventor: MULES ANDREW JOHN BRANDON
IPC: A61J11/00
Filed: 1998-04-09
Abstract: A disposable drinking container (10) having a nipple so as to be particularly suitable for use by infants. The drinking container has a container body (12) in the form of a small bottle or the like which is pre-filled with a drinking liquid, and a container closure (20). The container closure includes a flexible suckling nipple (25) for delivering drinking liquid from within the container body. The nipple is held to the container body by a cap rim (24) and the closure further includes a sealing portion (28) which initially seals the container and shields the nipple from contamination. The sealing portion is removable to expose the nipple for use. In one form the sealing portion may comprise a projection which is integrally formed with the cap rim, and frangibly detachable therefrom. In another form the sealing portion comprises a flexible disc which is sealed around a central aperture of the cap rim. The nipple may be adapted to be at least partially collapsible into the container body whilst the sealing portion is in place.
Patent NZ-501950-A (NZ)
Title: Medicinal compositions for application to mucosa
Inventor: NISHIBE YOSHIHISA
IPC: A61K9/10
Filed: 1999-04-21
Abstract: An aqueous pharmaceutical composition for application to the mucosa, comprising one or more water-insoluble substance, and one or more medicament, and having an osmotic pressure of less than 290 mOsm. Medicinal compositions for application to mucosa which are to be used in drug therapy, characterized by comprising one or more water-insoluble and/or hardly water-soluble substances, and one or more medicament, and having an osmotic pressure of less than 290 mOsm. These compositions provide an improved migration from the mucosa into blood. Medicinal compositions for application to mucosa which contain hemostatic compositions and drugs are also disclosed. These compositions provide an improved osmosis at the mucosa and the retentivity therein.
Patent NZ-504965-A (NZ)
Title: Pipe with cuff for forming pipe joint and polymer layers formed on interior and exterior of pipe and extending beyond pipe end to form bull nose
Inventor: ANDRE JAMES R
IPC: F16L9/16
Filed: 1998-12-08
Abstract: Disclosed is a method of forming a cuff (14) on a section of tubular pipe (10) which defines first and second ends and inner and outer surfaces. The method comprises the initial step of applying an outer layer of polymer (42) material to a portion of the outer surface of the pipe (12) such that a portion of the outer layer (42) extends beyond and covers the first end of the pipe. Thereafter, an inner layer of polymer material (46) is applied to a portion of the inner surface of the pipe. The inner layer (46) is then blended into the outer layer (42) so as to define a bull nose (44) of the cuff (14) which extends beyond the first end of the pipe (10).
Patent NZ-508205-A (NZ)
Title: Dispensing means with a wall mountable housing
Inventor: MCLISKY NIGEL HAIG
IPC: B65D83/14
Filed: 2000-11-17
Abstract: Dispensing means which have an integral self contained automatic spray dispenser (5) plus a wall mountable housing, the dispenser can be held by the housing such that it is substantially within and substantially concealed by the housing such that the dispenser can automatically and periodically emit a spray of spray material to an atmosphere outside of the housing, and wherein the dispenser can be subsequently detached from the housing when desired and placed apart from the housing to further automatically and periodically emit a spray of the spray material to a further atmosphere; the automatic dispenser is automatic in that it can be set to periodically emit the sprays without human intervention after the dispenser is so set, the dispenser is further characterised in that it has a spray delivery portion and a spray storage portion (6), the spray material storage (7) portion holds a supply of the spray material, and wherein the spray material storage portion is detachable from the spray delivery portion such that the spray material storage portion and thus the spray material can be replaced.
Patent NZ-508710-A (NZ)
Title: Fuel cell operated welder with at least one solid polymer proton conductor membrane between anode and cathode
Inventor: BLANKENSHIP GEORGE D
IPC: H01M8/00
Filed: 2000-12-07
Abstract: Fuel cell 100 provides voltage and current to welder 20, and at least one polymer proton conductor membrane (not shown) is positioned between anode and cathode. An organic feed and a mechanism (not shown) is provided to pass the feed past the anode.
Patent NZ-515871-A (NZ)
Title: Advanced floor mat
Inventor: BLUM RONALD D
IPC: A47L23/22
Filed: 2000-05-02
Abstract: An advanced floor mat is disclosed. In an embodiment of the present invention, the floor mat includes a cleanable portion. The floor mat may also include a water dissipation component, a water absorbing component, a cushioning component, customized graphics, a transparent cleanable portion, a tacky surface on the cleanable portion, an antibacterial composition, an antifungal composition, and a fragrance. The cleanable portion may be erodible and may include a plurality of cleanable reusable layers. If a tacky surface is included in the floor mat, an anti-slip feature may be associated with the tacky surface to help prevent slipping on a possibly wet tacky surface. Additionally, a sensor system may be included in the floor mat to assist a user in identifying when the floor mat may require cleaning
Patent NZ-516317-A (NZ)
Title: Stainless steel canister for propellant operated metering aerosols
Inventor: NAGEL JUERGEN
IPC: B21D51/24
Filed: 2000-05-24
Abstract: The invention relates to a corrosion-resistant special steel canister for propellant-containing aerosol formulations and used in propellant-driven inhalators.
Patent NZ-518402-A (NZ)
Title: Document processing system trays provided with electronic labels
IPC: G06K17/00
Filed: 2002-04-16
Abstract: Techniques for use of wireless labels to provide information relating to documents in a document processing operation are described. A plurality of document processing trays each have affixed a label for receiving and displaying messages which are received wirelessly from a central communication interface The messages provide information relating to documents to be placed within or contained within the trays. When a group of documents undergoes initial processing, the group of documents is sorted into a plurality of sorting locations. Each of the sorting locations has an associated tray and label and the documents within the sorting location are placed within the tray. Messages relating to the documents within each tray are transmitted and displayed on the label affixed to the tray. The messages provide information such as the large group, such as an entry, and sorting location to which the documents belong and the endpoint of the documents. The message may also provide information relating to the processing priority of the documents. As processing continues, new messages are transmitted appropriate to the processing stage of the documents. If documents are sorted into new sorting locations, new associations between the trays and the sorting locations are established and the documents are placed in and associated with trays and labels associated with the new sorting locations.
Patent NZ-528977-A (NZ)
Title: Nociceptin analogs for the treatment of pain
Inventor: SUN QUN
IPC: A61P25/32
Filed: 2002-04-18
Abstract: A compound of formula (IV) that is useful for modulating a pharmacodynamic response from opioid receptors centrally and/or peripherally is disclosed, wherein: Z, A, B, D, R, R1, R2, Q, and n are as described in the specification. These compounds are suitable for treating chronic and acute pain.
Patent NZ-535621-A (NZ)
Title: 1-oxa-3-aza-dibenzoazulenes as inhibitors of tumour necrosis factor production and intermediates for the production thereof
Inventor: MERCEP MLADEN
IPC: C07D498/04
Filed: 2003-04-09
Abstract: Disclosed is a process for production of and a compound of formula I wherein: X is a hetero atom of NRa where Ra is H or a protecting group, Y and Z are one or more substitutents linked to any available carbon atom independently selected from the list consisting of H, halogen, alkyl, alkenyl, alkynyl, halo-alkyl, hyroxy, alkoxy, trifluoromethyl, triflouromethoxy, alkanoyl, amino, amino-alkyl, N-amino, N,N-di(alkyl)amino, thiol, alkylthio, sulfonyl, alkylsulfonyl, sulfinyl, alkylsulfinyl, carboxy, alkoxycarmonyl, cyano and nitro, and R1 is selected from the list consisting of H, alkyl, CHO, (CH2)2COOH, (CH2)2CO2Et, (CH2)mL and a substituent of formula II as defined, wherin m is 1 or 3 and L is OH or Br. Compounds of formula I are disclosed use in a medicament for the treatment of inflammation. In particular the compounds are disclosed for their inhibition of tumour necrosis factor-alpha(TNF-alpha) and interleukin-1 (IL-1) production.
Patent NZ-536924-A (NZ)
Title: Load carrying platform with a hingedly connected top portion to facilitate vertical access.
Inventor: JOHNSON DARREN NOEL
Filed: 2004-12-01
Abstract: A load carrying compartment for a truck or trailer including a load carrying platform and a top section having a roof and roof supports. The roof supports are hinged to the load carrying platform and the top section is rotatable between a closed position and an open position. The open position provides access, preferably vertical access to the platform.
Patent NZ-540427-A (NZ)
Title: Methods for selectively inhibiting janus tyrosine kinase 3 (Jak3)
Inventor: KIRKEN ROBERT A
IPC: A61K31/13
Filed: 2003-12-09
Abstract: Disclosed is an in vitro method of inhibiting proliferation of a cell expressing Janus tyrosine kinase 3 comprising contacting the cell with at least one compound of formula (I) wherein; R1 is H, =CH2, CH2N(CH3)2, CH2SC(O)CH3, CH2SC6H5, CH2SCH2-(4-C-6-H4OCH3), CH2SC(O)C6H5 or CH2N(CH2CH3)2; R2 is O; R3 CH2N(CH3)2, CH2N(CH2CH3)2 or CH2-(N-morphyl); or a salt thereof, at a concentration effective to selectively inhibit Janus tyrosine kinase 3 activity, whereby jak3-dependent proliferation of said cell is suppressed.
Patent NZ-541313-A (NZ)
Title: Controller for reducing excessive amplitude of oscillation of free piston
Inventor: WOOD JAMES GARY
IPC: F16F15/03
Filed: 2004-03-10
Abstract: An apparatus for detecting and reducing excessive amplitude of oscillation of a free piston slidably mounted in a housing. The housing has a vibration absorber, including a mass mounted through a spring to the housing. The mass reciprocates relative to the housing along a path in a phase relationship to the piston. A sensor is mounted near the mass for detecting the amplitude of oscillation of the mass. A controller is connected to the sensor for reducing the amplitude of oscillation of the piston when the amplitude of oscillation of the mass reaches a predetermined maximum.
Patent NZ-542232-A (NZ)
Title: Modular drive wheel for log processors, delimbers and single grip harvesters
Inventor: DUVAL ALAIN
IPC: B27L1/00
Filed: 2004-02-03
Abstract: The modular drive wheel (20) for log processors includes a tubular midsection (26) sandwiched between a pair of annular rings (28, 30) mounted concentrically on opposite ends of the midsection. The midsection has a resilient outer surface extending around the midsection. The pair of annular rings each have a radially spaced apart array of notches (42, 62) therearound. The notches in the radially spaced apart arrays of notches are sized to snugly receive in releasable locking engagement therein links on opposite ends of chain segments (46) extending between the pair of annular rings. The drive wheel further includes means mounted between the pair of annular rings for selectively forcing apart the pair of annular rings along a longitudinal axis of symmetry of the midsection.
Patent NZ-544580-A (NZ)
Title: Functional influenza virus-like particles (VLPS)
Inventor: ROBINSON ROBIN A
IPC: A61K39/145
Filed: 2004-07-09
Abstract: Disclosed are recombinant influenza virus proteins, including influenza capsomers, subviral particles, virus-like particles (VLP), VLP complexes, and/or any portions of thereof, are provided as a vaccine for influenza viruses.; More specifically, this invention relates to the design and production of functional homotypic and heterotypic recombinant influenza virus-like particles (VLPs) comprised of recombinant structural proteins HA, NA and M1 of avian influenza virus type A/Hong Kong/1073/99 (H9N2) in baculovirus-infected insect cells and their application as a vaccine in the prevention of influenza infections and as a laboratory reagent for virus structural studies and clinical diagnostics.
Patent NZ-546112-A (NZ)
Title: Personal computer internet security system
Inventor: COPELAND SCOTT R
IPC: G06F21/00
Filed: 2004-01-02
Abstract: An intrusion secure personal computer system comprises: a central processing unit; a data storage means; a memory means; a primary operating system; a virtual machine operating system providing an isolated secondary operating environment functioning separate from the primary operating system and controlling operations of the personal computer system within the isolated secondary operating environment; and at least one input/output (I/O) connection in operative communication with an external data source. The operative communication with the external data source is isolated to the secondary operating environment and the wherein the personal computer system is secured from malicious code contained in a file downloaded from the external data source.
Patent NZ-549384-A (NZ)
Title: Leptin promoter polymorphisms and uses thereof
Inventor: MOORE STEPHEN STEWART
IPC: C12Q1/68
Filed: 2005-02-19
Abstract: Disclosed are single nucleotide polymorphisms (SNPs) in the leptin promoter, and methods for the identification of animals carrying specific alleles of these SNPs that are associated with circulating leptin levels, feed intake, growth rate, body weight, carcass merit and carcass composition. Also disclosed are oligonucleotides that can be used as primers and/or probes to amplify and/or detect these SNPs, and provides methods for selecting and grouping animals, in particular bovines, according to genotype.