baber/WOPTO huggingface dataset:
Patent CA-2678900-C (CA)
Inventor: TRACEY JAMES B A
IPC: A01G25/16
Filed: 2008-02-22
Granted: 2015-05-12
Abstract: An apparatus (1) includes a handheld element (100, 101) and a remote control (7). The handheld element (100, 101) has a proximal end (102), a distal end (104), and an internal flow conduit. The internal flow conduit (57) extends between the proximal (102) and distal (104) ends. The internal flow conduit (57) is configured to be in fluid communication with a hose (5). The remote control (7) is integrated with the handheld element (100, 101). The remote control (7) is configured to transmit wireless data signals for controlling a plurality of devices associated with the hose. The plurality of devices may include a reel (2), a valve system (3), a valve unit (52), and/or a plurality of valves (46).
Patent CA-2682661-C (CA)
Inventor: SHEIKH NADEEM
IPC: C12Q1/00
Filed: 2008-03-21
Granted: 2017-03-14
Abstract: The present invention relates to the discovery of novel methods of inducing a natural killer (NK) cell-mediated immune response and increasing NK activity in a mammal for the treatment of tumors and virus infections. The method comprises the steps of isolating peripheral blood mononuclear cells (PBMCs) from the subject, exposing the PBMCs in vitro to protein conjugate comprising granulocyte macrophage colony stimulating factor (GM-CSF) covalently linked to a soluble peptide antigen, under conditions effective to activate the PBMCs, and administering the activated PBMCs to the subject. The invention also relates to a method of detecting in a subject a cytotoxic NK cell-meditated immune response or NK cell activity in vitro by CD336 expression and/or lysis of the K562 tumor line. The invention further relates to a method for determining whether a subject has had a therapeutically effective response to a protein conjugate by assessing the NK activity of activated PBMCs from the subject.
Patent CA-2686013-C (CA)
Inventor: PLANCK RANDY L
IPC: E01F13/08
Filed: 2009-11-23
Granted: 2015-06-16
Abstract: A post (200) for use with an automatically-movable barrier (1203) and a motive actuator (1204) is configured to interact with the barrier to thereby facilitate movement of the barrier with respect to the post. This post can have at least one cavity (201, 801) formed axially therein and a mains-power-bearing pathway (202) disposed within this at least one cavity to convey mains electrical power to moveable barrier control circuitry (1202) as well as the motive actuator. Such a post can further comprise one or more integral pivot points (1001) that are configured to pivotally engage the automatically-movable barrier such that the automatically-movable barrier can selectively pivot about the integral pivot point. By another approach, such a post can further comprise one or more rollers (1101) that are configured to engage the automatically-movable barrier such that the latter can selectively move in a lateral direction through engagement with the roller(s).
Patent CA-2689582-C (CA)
Inventor: CLINE JOHN
IPC: A61F5/44
Filed: 2008-06-11
Granted: 2016-08-09
Abstract: A stoma adapter is described that is especially suited to a recessed stoma or a flush stoma. The stoma adapter effectively extends the discharge passage from the stoma, protects peristomal skin, and forms a bridge at the interface between the stoma and an ostomy appliance. The stoma adapter contains a substantially unobstructed discharge passage, at least for effluent flowing in a discharge direction. The stoma adapter includes a seal for sealing against the bowel wall. The stoma adapter has collapsing, expanding, flexible and reinforced designs.
Patent CA-2708442-C (CA)
Inventor: BOSWELL ROBERT F JR
IPC: C07D471/14
Filed: 2003-06-02
Granted: 2012-01-10
Abstract: Intermediates of nevirapine and processes for making intermediates of nevirapine.  One such intermediate is N-(2-halo-4-methyl-3-pyridinyl)-2-(cyclopropylamino)-pyridinecarboxamide, which may be produced by (a) treating 2-(cyclopropylamino)-3-pyridine carboxylic acid with a chlorinating agent, to yield 2-(cyclopropylamino)-3-pyridinecarbonyl chloride; and (b) reacting the 2-(cyclopropylamino)-3-pyridine carbonyl chloride with a 2-halo-4-methyl-3-pyridinamine of the formula (see above formula) wherein X is a fluorine, chlorine, bromine or iodine atom, to produce the N-(2-halo-4-methyl-3-pyridinyl)-2-(cyclopropylamino)-3-pyridinecarboxamide.
Patent CA-2710760-C (CA)
Title: Recepteur de type toll 3 de cynomolgus
Inventor: BECK HEENA
IPC: C12Q1/00
Filed: 2008-12-23
Granted: 2017-05-16
Abstract: La présente invention concerne des polynucléotides isolés codant pour le récepteur de type Toll 3 de cynomolgus (cynoTLR3), des polypeptides pouvant être obtenus par l'expression de ces polynucléotides, des cellules recombinantes, des procédés et des utilisations de ceux-ci.
Patent CA-2712714-C (CA)
Title: Folates, compositions et utilisations associees
Inventor: VALOTI ERMANNO
IPC: C07D475/04
Filed: 2008-02-20
Granted: 2015-05-12
Abstract: La présente invention concerne des folates, des compositions et des utilisations associées. Notamment, l'invention concerne un composé cristallin ou amorphe qui est un folate substitué ou non substitué ou un folate réduit, ou les isomères naturels ou non naturels associés d'au moins une base organique, ainsi que des compositions et des utilisations associées. Les composés de l'invention présentent une stabilité durable et également une solubilité dans l'eau particulièrement élevée.
Patent CA-2714996-C (CA)
Title: Methods, compositions, uses, and kits useful for vitamin d deficiency and related disorders
Inventor: PETKOVICH P MARTIN
IPC: C12Q1/68
Filed: 2009-04-02
Granted: 2020-04-07
Abstract: Methods for diagnosing, treating, and preventing catabolism-related vitamin D  deficiency and related disorders; related compositions, apparatus and kits, are disclosed. A method involves measuring CYP24 expression and/or activity, or a proxy thereof such as FGF23 level, in a patient and correlating abnormally elevated CYP24 expression and/or activity with catabolism-related vitamin D deficiency or with susceptibility for catabolism-related vitamin D  deficiency. In response to abnormally elevated CYP24 expression and/or activity, the method further includes administering a CYP24 inhibitor to the vitamin D deficient or at-risk patient, and preferably avoiding activation of the vitamin D binding receptor, such as by avoiding administration of active vitamin D compounds to such patients. Optionally, a vitamin D prohormone or prohormone can be administered.
Patent CA-2715456-C (CA)
Inventor: MUELLER BERNHARD K
IPC: C07K16/46
Filed: 2009-02-27
Granted: 2020-10-27
Abstract: The subject invention relates to isolated proteins, particularly monoclonal antibodies, which bind and neutralize RGM A protein. Specifically, these antibodies have the ability to inhibit the binding of RGM A to its receptor and/or coreceptors. These antibodies or portions thereof of the invention are useful for detecting RGM A and for inhibiting RGM A activity, for example in a human suffering from a disorder including but not limited to multiple sclerosis, mammalian brain trauma, spinal cord injury, stroke, neurodegenerative diseases, and schizophrenia.
Patent CA-2716023-C (CA)
Inventor: DINO DAVID
IPC: E21B21/06
Filed: 2009-02-11
Granted: 2016-10-25
Abstract: A method of providing a substantially constant rheological profile of a drilling fluid over a temperature range of about 120°F to about 40°F includes adding a drilling fluid additive to the drilling fluid, wherein the drilling fluid additive includes the reaction product of a carboxylic acid with at least two carboxylic moieties; and a polyamine having an amine functionality of two or more. A composition, such as an oil based drilling fluid, includes the reaction product of a carboxylic acid with at least two carboxylic moieties and a polyamine having an amine functionality of two or more.
Patent CA-2717775-C (CA)
Title: Method for producing a film element
Inventor: BREHM LUDWIG
IPC: B42D15/00
Filed: 2009-02-28
Granted: 2015-12-22
Abstract: The invention concerns a process for producing a film element having mutually registered metallic layers (11, 16) and a film element which can be produced by such a process. A first metallic layer (11) provided on a first surface of a flexible single-layer or multi-layer carrier film (10) and a masking layer (13) provided on the second surface of the carrier film (10), opposite to the first surface, are structured in accurate register relationship with each other by means of mutually synchronised structuring procedures. After structuring of the first metallic layer (11) and the masking layer (13) one or more further layers are applied to the first metallic layer (11). Applied to the one or more further layers (15) is a second metallic layer (16) to which a first photoactivatable layer (17) is applied. The first photoactivatable layer (17) is structured by means of trans-exposure through the masking layer (13), the first metallic layer, the one or more further layers and the second metallic layer (16) from the side of the masking layer (13) by means of electromagnetic radiation of a wavelength to which the first photoactivatable layer (17) is sensitive, or the first photoactivatable layer is exposed controlledly through the masking layer from the side of the film body that is opposite to the masking layer.
Patent CA-2718065-C (CA)
Inventor: ASMUSSEN BODO
IPC: A61K9/00
Filed: 2009-02-27
Granted: 2016-02-16
Abstract: The present invention relates to strip-shaped forms of administration for administering an active ingredient via the mucous membrane of the gums.
Patent CA-2719552-C (CA)
Title: Device for dispensing a liquid in the form of drops
Inventor: PAINCHAUD GAETAN
IPC: B65D47/18
Filed: 2009-03-27
Granted: 2016-01-19
Abstract: The invention relates to a device for dispensing predetermined doses of a liquid, that comprises a sealing member (14) that can assume a liquid release position for letting the fluid out of the device, and a check position for preventing the liquid from flowing back inside the device. The sealing member (14) comprises means for dosing the liquid to be dispensed (44, 46).
Patent CA-2723310-C (CA)
Inventor: SIEVERNICH BERND
IPC: A01N43/50
Filed: 2009-05-20
Granted: 2018-07-17
Abstract: The present invention relates to a herbicidal composition which comprises: a) at least one herbicide A selected from glyphosate, glufosinate and their salts, and b) a herbicide B which is 3-[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)pyrazol-4-ylmethylsuIfonyl]-4,5-dihydro-5, 5-dimethyl-1,2-oxazole [common name:pyroxasulfone]. The present invention relates in particular to a herbicidal composition comprising: a) at least one herbicide A  selected from glyphosate, glufosinate and their salts, b) a herbicide B which is 3-[5-(difluoromethoxy) -1-methyl-3-(trifluoromethyl)pyrazol-4-ylmethylsulfonyl]-4,5-dihydro-5,5-dimethyl-1,2-oxazole [common name:pyroxasulfone], and c) at least one further herbicide C, which is selected from the herbicide groups C.1 to C.8: C.1 herbicides of the group of acetolactate synthase inhibitors (ALS inhibitors), C.2 herbicides of the group of protoporphyrinogen oxidase inhibitors (PPO inhibitors), C.3 herbicides of the group of auxins, C.4 herbicides of the group of 4-hydroxyphenyl-pyruvate-dioxygenase inhibitors (HPPD inhibitors), C.5 herbicides of the group of phytoene desaturase inhibitors (PDS inhibitors), C.6 herbicides of the group of photosystem II inhibitors (PSII inhibitors), C.7 herbicides of the group of microtubulin inhibitors, and C.8 herbicides of the group of inhibitors of the synthesis of very long chain fatty acids (VLCFA inhibitors).
Patent CA-2727130-C (CA)
Title: Matelas d'evacuation
Inventor: KENALTY CHRISTOPHER
IPC: A61G1/01
Filed: 2009-06-05
Granted: 2017-08-22
Abstract: L'invention porte sur un matelas d'évacuation qui comprend un matelas monobloc comprenant un intérieur de matelas, un drap de face supérieure de matelas, quatre draps de face latérale de matelas et un drap inférieur. Le drap inférieur forme à la fois le drap de face inférieure de matelas et un drap d'évacuation inférieur. Le matelas d'évacuation monobloc comprend également un drap d'évacuation supérieur configuré pour être déployé sur un patient qui est disposé au-dessus du drap de face supérieure de matelas. Le matelas d'évacuation monobloc comprend en outre une structure de fixation configurée pour fixer le drap d'évacuation supérieur au patient et au matelas monobloc. Une structure de transport est également comprise dans le matelas d'évacuation monobloc et est configurée pour qu'une personne puisse tirer le patient sécurisé et le matelas monobloc hors d'un hôpital.
Patent CA-2727292-C (CA)
Inventor: KAZEROONI HOMAYOON
IPC: A61H3/00
Filed: 2009-06-11
Granted: 2015-03-31
Abstract: A walking assist device, which is to be worn on a person's leg, includes a shank link, a thigh member, and a knee mechanism. The thigh member is in contact with the person's thigh when the device is worn on the person's leg. The knee mechanism rotatably connects the shank link to the thigh member. When the shank link is in contact with the ground, the knee mechanism is configured to resist the rotation of the shank link relative to the thigh member to prevent the person's foot from contacting the ground and reduces ground reaction forces entering the person's foot.
Patent CA-2727933-C (CA)
Title: Systeme et procede de detection de chauve-souris et de leur impact sur les installations eoliennes
Inventor: ADLER MICHAEL J
IPC: G01S1/72
Filed: 2009-06-17
Granted: 2017-09-19
Abstract: La présente invention concerne un système et un procédé pour détecter les chauves-souris à distance. Dans un aspect, l'invention concerne un système de détection de chauves-souris comprenant une unité de détection supérieure connectée à une unité informatique de base. L'unité de détection supérieure peut être placée sur une structure verticale, et une seconde unité de détection inférieure, ou des unités de détection additionnelles, peuvent également être positionnées sur la structure verticale. Chaque unité de détection comprend un boîtier qui est relié à un détecteur audio et comprend un détecteur audio. L'unité informatique de base est enfermée dans un boîtier et comprend un processeur de données, un dispositif de stockage de données, et un dispositif d'interface de communication distant. Le processeur de données est connecté opérationnellement au dispositif de stockage de données, au dispositif d'interface de communication à distance, et aux détecteurs audio de toute unité de détection placée sur la structure verticale. L'unité informatique de base communique avec un ordinateur distant transférant les informations relatives aux sons des chauves-souris détectés par les unités de détection.
Patent CA-2729217-C (CA)
Title: 6-substituted phenoxychroman carboxylic acid derivatives
Inventor: BURGESS LAURENCE E
IPC: C07D407/12
Filed: 2009-06-24
Granted: 2016-09-06
Abstract: Compounds of Formula (I): in which A1, A2, W, L, G, R7a, R7b, R8, R9 and R10 have the meanings given in the specification, are DP2 receptor modulators useful in the treatment of immunologic diseases.
Patent CA-2729254-C (CA)
Inventor: KHABAR KHALID S ABU
IPC: C12N15/79
Filed: 2008-11-17
Granted: 2015-02-24
Abstract: The present invention relates to expression vector comprising (a) a promoter region comprising a non-inducible constitutively active ribosomal protein gene promoter, (b) an operably linked reporter or gene sequence, and (c) a 3' untranslated region (3' UTR), which are suitable means for an selective assessment of post-transcriptional regulation, post-transcriptional con-trol elements and factors as well as for identifying compounds that effect post-transcription. The present invention furthermore re-lates to arrays, expression vector libraries and cell lines containing the expression vector(s). The present invention furthermore re-lates to a method and kit for identifying compounds that affect post-transcriptional regulation of reporter(s) or gene(s), that utilize the expression vector(s).
Patent CA-2729483-C (CA)
Inventor: ELLIOTT RUSSELL PHILLIP
IPC: A61K8/29
Filed: 2009-06-24
Granted: 2013-08-06
Abstract: Cosmetic composition providing a high coverage of skin while retaining a natural skin appearance comprising iron oxide particles having an average surface area from 30 m2/g to 150 m2/g, iron-containing titanium dioxide particles having an average surface area from 1 m2/g to 30 m2/g and comprising from 1% to 15% iron by weight of the titanium dioxide, and a cosmetically acceptable carrier and its use as a foundation and/or as a composition to correct skin discoloration surrounding the eye.
Patent CA-2740601-C (CA)
Inventor: HUANG MICHELLE KUN
IPC: F21V5/00
Filed: 2009-12-02
Granted: 2013-06-25
Abstract: A lamp including a two-sided source plate, a plural-ity of light sources, a lens, a diffuser plate, and a driver insulator is disclosed. One set of the light sources generates white light and is attached to one side of the source plate. Another set of the light sources generates colored light and is attached to the source plate's other side. The lens encapsulates the white light-generating set, and redirects that white light. The driver insulator and the diffuser plate are each in contact with the source plate's other side. The driver in-sulator, diffuser plate, and that side of the source plate define a light box region that contains the colored light-generating set of light sources. The driver insulator acts as a reflector, and the diffus-er plate acts as a diffuser, such that colored light is dispersed from the light box region through the diffuser plate.
Patent CA-2740915-C (CA)
Inventor: ATZ JUERG
IPC: A01K61/10
Filed: 2009-10-22
Granted: 2017-05-02
Abstract: A net (11) is particularly suitable for a basket for pisiculture, which may be placed in sea or fresh water (16).  The net (11) is made of a wire material (1), producible from individual spiral or simi-larly bent longitudinal elements, wherein adjacent threads (2, 3, 4, 5) are woven to-gether. Said net is simple and economical to produce.
Patent CA-2742242-C (CA)
Inventor: ZUGMAIER GERHARD
IPC: C07K16/28
Filed: 2009-11-06
Granted: 2023-01-10
Abstract: The present invention relates to a pharmaceutical composition for use in the treatment, amelioration or elimination of pediatric acute lymphoblastic leukemia (ALL), in a pediatric ALL patient, comprising a CD19xCD3 bispecific single chain antibody construct and a pharmaceutically acceptable carrier. The present invention further relates to the use of a CD19xCD3 bispecific single chain antibody construct for treatment, amelioration or elimination of pediatric acute lymphoblastic leukemia (ALL) in a pediatric ALL patient or for preparation of a medicament for treatment amelioration or elimination of pediatric acute lymphoblastic leukemia (ALL) in a pediatric ALL patient.
Patent CA-2744883-C (CA)
Inventor: HEMBISE DOMINIQUE
IPC: F41H11/16
Filed: 2009-12-08
Granted: 2016-07-19
Abstract: The invention relates to a mechanical connection device between a motorised vehicle and working equipment. According to the invention, the device (4) includes a rigid plate (25) mounted by means of axles (3) in the tow rings (20) of the vehicle and bearing adjustable skids (33) that are applied against a transverse surface of the vehicle, such as to butt the connection device to the vehicle, thereby securing same.
Patent CA-2746334-C (CA)
Title: Remedes contre le pemphigus, a base d'anticorps diriges contre le ligand fas
Inventor: PINCELLI CARLO
IPC: A61K39/395
Filed: 2009-12-14
Granted: 2018-06-12
Abstract: La présente invention concerne l'utilisation d'antagonistes de FasL, par exemple d'anticorps humanisés dirigés contre les ligands Fas humains, que l'on appelle aussi CD95L ou Apo1L, et que l'on regroupe ici sous l'abréviation "FasL", cette utilisation étant destinée à la prévention et/ou au traitement de maladies de la peau associées à l'acantholyse des kératinocytes, et en particulier la prévention et/ou le traitement du pemphigus.
Patent CA-2746600-C (CA)
Inventor: TERRENOIRE ALEXANDRE
IPC: C09J133/00
Filed: 2009-12-21
Granted: 2016-09-13
Abstract: The present invention relates to polymer dispersion-based binder compositions comprising boric acid or salts of boric acid as cross-linking agents, to a method for the production thereof and to use thereof. The aqueous binder composition comprises: a) a water-insoluble polymer (P) in the form of dispersed polymer particles with a glass transition temperature in the range of -50°C to 50°C, obtained through radical polymerization of ethylenically unsaturated monomers M, wherein the monomers M contain: 80 to 99.9 wt %, relative to the total amount of monomers M, of at least one slightly soluble neutral monoethylenically unsaturated monomer M1; and 0.1 to 20 wt %, relative to the total amount of monomers M, of at least one monoethylenically unsaturated monomer M2 that contains at least one carboxyl group and/or at least one carboxylic acid amide group (CON-H2); and b) boric acid and/or at least one salt of boric acid.
Patent CA-2749866-C (CA)
Inventor: MCCOUBREY NEIL
IPC: B64F5/45
Filed: 2010-01-16
Granted: 2019-05-28
Abstract: La présente invention se rapporte à un ensemble mobile autonome pouvant être utilisé pour l'entretien de zone éloignée et la réparation de dégâts indésirables sur une paroi de cuve à espace confiné. L'ensemble comprend un train roulant comprenant une base roue, un logement monté au-dessus de la base roue et délimitant un espace interne pouvant recevoir et retenir l'équipement de réparation et d'entretien destiné à réparer ladite cuve. L'équipement comprend un kit de décrassage, un moyen pour permettre le descellement et le rescellement d'un intérieur de la cuve à espace confiné, un moyen pour permettre la décontamination d'air dans la cuve; et un kit de respiration destiné à un utilisateur pour accéder de façon sécurisée à l'espace interne et réparer les dégâts indésirables depuis l'intérieur de l'espace confiné.
Patent CA-2751826-C (CA)
Inventor: SPENCER JOHN ROLLAND
IPC: B21D53/06
Filed: 2011-09-07
Granted: 2014-04-15
Abstract: A clamp ring and process for manufacturing a clamp ring to effectively reduce, if not eliminate, waste scrap from the manufacturing process. The clamp ring and process for manufacturing the same, results in clamp ring having a seam formed by a metal joining technique such as welding, brazing, bolting, soldering, and clinching.
Patent CA-2752059-C (CA)
Inventor: KJORHOLT HALVOR
IPC: E21B43/30
Filed: 2010-02-10
Granted: 2017-06-06
Abstract: The present invention provides a method for recovering hydrocarbons from a sub-surface reservoir having present therein a wellbore in which a production conduit and an injection conduit are located, said method comprising injecting a heating fluid into the reservoir via said injection conduit, characterised in that said heating fluid is released via a plurality of discrete permeable sections (injection sections) located along the length of the injection conduit and produced hydrocarbons are collected via a plurality of discrete permeable sections (production sections) located along the length of the production conduit.
Patent CA-2759898-C (CA)
Title: Amelioration de la capture du carbone dans un processus de fermentation
Inventor: OAKLEY SIMON DAVID
IPC: C12P7/06
Filed: 2010-04-29
Granted: 2013-07-16
Abstract: Cette invention concerne l'amélioration de l'efficacité de la gazéification utilisée avec la fermentation d'un gaz de synthèse. L'invention concerne en particulier l'augmentation de l'efficacité globale de la capture du carbone d'un processus de gazéification/fermentation pour obtenir des produits comme les alcools.