baber/WOPTO huggingface dataset:
Patent NZ-260566-A (NZ)
Title: N-[2-(3,4-dichlorophenyl)-4-[4-substituted piperidino]butyl]-n-methyl-benzamide derivatives and pharmaceutical compositions
Inventor: JACOBS ROBERT TOMS
IPC: C07D401/04
Filed: 1994-05-20
Abstract: The present invention concerns the novel aryl substituted heterocycles of formula I, set out below, <CHEM> wherein R<2>, R<3> and R<4> have the values defined herein, which antagonize the pharmacological actions of one of the endogenous neuropeptide tachykinins at the neurokinin 2 (NK2) receptor making them useful whenever such antagonism is desired, such as in the treatment of asthma and related conditions. The invention also provides pharmaceutical compositions containing the aryl substituted heterocycles for use in such treatment, methods for their use, and processes and novel intermediates for their manufacture.
Patent NZ-271739-A (NZ)
Title: Cyclodepsipeptide compounds and pharmaceutical compositions thereof
Inventor: NISHIYAMA HITOSHI
IPC: C07D273/00
Filed: 1994-08-31
Abstract: A compound of the formula : <CHEM>  wherein   A   is benzyl group which has suitable substituent (s), A<a>, B and D   are each lower alkyl, C   is hydrogen or lower alkyl,  or a salt thereof. The compound or its salt of the present invention has excellent parasiticidal activities as parasiticides (anthelmintics) for animals and human bodies.
Patent NZ-303185-A (NZ)
Title: Preparation of n-substituted pyrazoles by reaction of a pyrazole with an alcohol
Inventor: MERKLE HANS RUPERT
IPC: C07D231/12
Filed: 1996-02-27
Abstract: PCT No. PCT/EP96/00790 Sec. 371 Date Aug. 20, 1997 Sec. 102(e) Date Aug. 20, 1997 PCT Filed Feb. 27, 1996 PCT Pub. No. WO96/27589 PCT Pub. Date Sep. 12, 1996A process for the preparation of an N-alkyl- or N-phenylalkyl-substituted pyrazole I by reacting the corresponding N-unsubstituted pyrazole II with an alcohol III of the formula R1-OH where R1 is the same alkyl or phenylalkyl group to be added to the unsubstituted nitrogen group -NH- of the pyrazole reactant. Both of the reactants, i.e. the pyrazole II and alcohol III compounds, are catalytically reacted in the liquid phase in a molar ratio of from 0.001:1 to 1:1, at temperatures of 50 DEG -400 DEG  C. and under a subatmosheric pressure of from 0.8 bar up to a superatmospheric pressure of 250 bar. The catalyst required for this liquid phase reaction is selected as being at least one or more non-heterogeneous acid catalysts, their alkyl esters or their acid anhydrides.
Patent NZ-315018-A (NZ)
Title: Synchronising direct connection between mobile telephones
Inventor: KINNUNEN KIMMO
IPC: H04W56/00
Filed: 1996-08-13
Abstract: method for synchronizing a telecommunications connection in a mobile communications system comprises at least one base station and a first and at least a second mobile station communicating on a direct mode channel.  In accordance with the method, the first mobile station operating on the direct mode channel, transmits a registration message to the base station of the mobile communications system on a system channel of the mobile communications system.  The registration message indicates the wish of the first mobile station to operate in the dual watch mode on the control channel of the mobile communications system.  In response to the registration message, a specific control channel of the base station and the timing information related to the control channel are communicated to the first mobile station.  The first mobile station switches (811) to the dual watch mode in order to communicate either on the direct mode channel or on the allocated control channel during the time indicated by the timing information.
Patent NZ-331329-A (NZ)
Title: method of producing an antimicrobial effect in alcohol or water based electrolyte by bringing into contact with the electrolyte a silver containing material
Inventor: BURRELL ROBERT EDWARD
IPC: A01N59/26
Filed: 1994-11-01
Abstract: Anti-microbial coatings and powders and method of forming same on medical devices are provides. The coatings are preferably formed by depositing an anti-microbial biocompatible metal by vapour deposition techniques to produce atomic disorder in the coating such that a sustained release of metal ions sufficient to produce an anti-microbial effect is achieved. Preferred deposition conditions to achieve atomic disorder include a lower than normal substrate temperature, and one or more of a higher than normal working gas pressure and a lower than normal angle of incidence of coating flux. Anti-microbial powders formed by vapour deposition or altered by mechanical working to produce atomic disorder are also provided. The anti-microbial effect of the coatings or powders may be further activated or enhanced by irradiating with a low linear energy transfer form of radiation such as gamma radiation. Novel anti-microbial silver materials are defined, characterized by having a positive rest potential, a Trec/Tm less than 0.33, and a grain size less than 200 nm. Anti-microbial fine grain or nanocrystalline materials are provided, together with methods of preparation, wherein the anti-microbial metal if deposited in a matrix with atoms or molecules of a different material such as other biocompatible metals (ex. Ta), trapped or absorbed oxygen, or compounds of anti-microbial metals or biocompatible metals (ex. Ag0 or TaO). The invention also extends to a method of producing an anti-microbial effect with silver materials that form complex silver ions other than Ag+, Ag2+ and Ag3+.
Patent NZ-336155-A (NZ)
Title: Absorbent product with a top layer having a central portion of woven material and side portions of perforated plastic film
Inventor: DE CARVALHO ANTONIO CARLOS RIB
IPC: A61F13/15
Filed: 1999-06-04
Abstract: This absorbent product which is adapted to be worn in a user's undergarment includes: An absorbent body covered by a surface layer. The surface layer comprises opposite longitudinally extending first portions covering the sides of the absorbent body and a centrally located longitudinally extended second portion.  The first portions are perforated plastic film and the second portions is a non-woven fabric, and the first and second portions are both liquid impermeable.
Patent NZ-500973-A (NZ)
Title: Locating lightning strikes using pairs of receiving stations detecting VLF waveforms from strike
Inventor: BRUNDELL JAMES BLAIR
IPC: G01S3/02
Filed: 1999-11-11
Abstract: A lightning detection system uses receiver stations 10 - 13 to receive VLF emission from a lightning strike 15.  The receiver stations are connected by a communications network such as the Internet.  At each station the VLF waveform of the strike and the time of arrival of the waveform is stored.  The receiving stations are then configured as pairs, so that the wave form stored in each station is compared with that in each of the others in turn to produce a set of arrival time difference figures.  For each station pair, a residual time difference caused by the detection of the emission being triggered by different parts of the waveform at each station of the pair is calculated.  The arrival time differences and the residual time differences are then used to determine the location of the lightning strike.
Patent NZ-506199-A (NZ)
Title: Producing protected protein for ruminant feed by combining protein with reducing carbohydrate
Inventor: WOODROOFE JONATHAN MALCOLM
IPC: A23J3/14
Filed: 1995-08-07
Abstract: A process for preparing a ruminant feed or feed supplement comprises: ai) mixing together a reducing carbohydrate with a protein containing material such that the reducing carbohydrate is present in the mix at between 6 to 15% by weight of the protein and if necessary adjusting the moisture content of the mix to between 10-30% and pH to between 6 to 9; aii) applying shear forces and pressures between 300 to 500 psi whilst concurrently heating the material to between 100 to 165oC; aiii) maintaining the temperature of the processed mixture above 70oC for a period of 15 minutes up to 24 hours and aiv) cooling and drying the mixture to a level where it is stable for storage or bi) mixing together a reducing carbohydrate with a protein containing material such that the reducing carbohydrate is present in the mix at between 0.5 to 50% by weight of the protein and if necessary adjusting the moisture content of the mix to between 10-40% and pH to between 6 to 9; bii) passing the mixture through a cooker extruder or an expander so as to achieve final extrusion temperatures of between 80 to 190oC and so as to apply not only heat but also shear force, extra water and pressure of 30 to 700 psi; biii) maintaining the temperature of the processed mixture above 30oC for a period of 15 minutes up to 24 hours and biv) cooling and drying the mixture to a level where it is stable for storage.
Patent NZ-506669-A (NZ)
Title: Text processor to enhance the presentation of text by varying the text presentation in accordance with text specific attributes
Inventor: RANDALL C WALKER
IPC: G06F17/21
Filed: 1999-02-02
Abstract: A text enhancement method and apparatus for the presentation of text for improved human reading. The method includes extracting text specific attributes from machine readable text and varying the text presentation in accordance with the attributes. The preferred embodiment of the method: extracts parts of speech and punctuation from a sentence, applies folding rules which use the parts of speech to determine folding points, and presents text segments each on a new line and having a determined horizontal displacement based on the text specific attributes. One method displays text over bent curves having a shape based on text content. Another method includes displaying relative text position within a hierarchy using alternating vertically and horizontally tiled planes. Another method supports reading text segments across opposed pages without waiting for paging. Yet another method displays text to allow reading from bottom to top as though from front to back. Still another method displays words in colors reflecting the relationships between the words and the larger text segments of which they are apart.
Patent NZ-508248-A (NZ)
Title: Camptothecin analogue compounds and pharmaceutical use
Inventor: ATASSI GHANEM
IPC: C07D471/14
Filed: 2000-11-17
Abstract: In the compounds of formula (I): n is 0, 1 or 2 R1, R2, R3, R4 and R5 are selected from H, halogen, alkyl, alkenyl, alkynyl, perhaloalkyl, C3-C11 cycloalkyl, C3-C11 cycloalkyl-alkyl, hydroxy, hydroxyalkyl, alkoxy, alkoxyalkyl, alkoxycarbonyl, acyloxy, carboxy, nitro, cyano, aminocarbonyl, (CH2)pNRaRb and OC(O)NRaRb,  wherein p is 0 to 6, Ra and Rb are H, alkyl, C3-C11cycloalkyl, C3-C11 cycloalkyl-alkyl, acyl, optionally substituted aryl or arylalkyl group, or Ra and Rb form together with the nitrogen atom carrying them a pyrrolyl, piperidinyl or piperazinyl group, wherein each of those cyclic groups may be optionally substituted; or Two adjacent groups R2, R3, R4 and R5 form together with the carbon atoms carrying them, a group O(CH2)tO, wherein t is 1-3; R60, R70n, R80 and R90 are selected form H, hydroxy, alkoxy, O-(CO)-X or O(CO)NXW, wherein X and W are alkyl, alkenyl, alkynyl, C3-C11 cycloalkyl, C3-C11 cycloalkyl-alkyl or an optionally substituted aryl or arylalkyl group; R61, R71n, R81 and R91 is H, alkyl, alkenyl or alkynyl, or taken in pairs on adjacent carbon atoms, together form a bond or an oxirane group, or two geminal groups (R60 and R61) and/or (R70 and R71) and/or (R80 and R81) and/or (R90 and R91) together form an oxo group or a group O(CH2)t1O, wherein t1 is 1 to 3. The compounds may be used in pharmaceuticals for the treatment of cancerous diseases.
Patent NZ-508602-A (NZ)
Title: The production of primmorphs from disassociated cells of sponges, corals and other invertebrates, and use thereof
Inventor: MULLER WERNER EG
IPC: C12N5/07
Filed: 1999-05-06
Abstract: A method of preparing and culturing primmorphs from sponges, corals, and Bryoza characterised in that single cells are recovered after dissociation from the tissue formation of living animals and brought into proliferation in vitro under culture conditions which allow three dimensional primmorph formation.
Patent NZ-511963-A (NZ)
Title: Oxazolidinone antibacterial agents having a thiocarbonyl functionality
Inventor: PERRICONE SALVATORE CHARLES
IPC: C07D413/10
Filed: 1998-11-27
Abstract: Described is a compound of the formula (I), where: Z2 is -O2S-, -O-, -N(R107)-, -OS-, or-S-; w is 0, 1, 2, or 3; R23 and R24 are the same or different and can be H or F; and R1 is H; NH2; NHalkyl; N(alkyl)2; a group of formula (II); alkyl; Oalkyl; Salkyl; alkyl substituted with 1-3 F, 1-2 Cl, CN, or -COOalkyl, or cycloalkyl, wherein in each occurrence the alkyl group may be straight or branched; and R107 is R102O-C(R110)(R111)-C(O)-, R103O-C(O)-, R108-C(O)-, R109-SO2-, NC-CH2-, FCHCH2-, or R150R151NSO2-; wherein R102 is H, CH3-, phenyl-CH2-, or CH3C(O); each of R110 and R111 is selected from H or CH3; R103 is alkyl or phenyl; R108 is H, alkyl, aryl(CH2)0-5, CNCH2-, ClCH2-, Cl2HC-, FH2C-, F2HC- , or cycloalkyl; R150 and R151 are the same or different and are selected from H, alkyl, or R150 and R151 taken together with the nitrogen to which each is attached forms a monocyclic heterocyclic ring having from 3 to 6 carbon atoms; and R109 is alkyl, -CH2Cl, -CH2CH=CH2, aryl or -CH2CN.
Patent NZ-512025-A (NZ)
Title: Acetylenic beta-sulphonamido and phosphinic acid amide hydroxamic acid TACE inhibitors
Inventor: ZASK ARIE
IPC: A61P15/06
Filed: 2000-01-27
Abstract: A hydroxamide acid derivative or a pharmaceutically acceptable salt thereof has the formula (B) wherein: the C(=O)NHOH moiety and the -NR5- moiety are bonded to adjacent carbons; X is SO2 or -P(O)R10; Y is phenyl, naphthyl or 5-10 membered heteroaryl ring having from 1-3 heteroatoms with the proviso that X and Z may not be bonded to adjacent atoms of Y; Z is O, NH, CH2 or S; R5 is hydrogen or alkyl; R6 and R7 are independently, hydrogen or methyl; R8 is hydrogen, optionally substituted alkyl, alkenyl, alkynyl or cycloalkyl, phenyl or a 5-7 membered heteroaryl or heterocycloalkyl having 1-3 heteroatoms; R9 is hydrogen, alkyl, cycloalkyl, or phenyl; R10 is alkyl, cycloalkyl, phenyl, or 5-7 membered heteroaryl having 1-3 heteroatoms; R11 and R12 are independently, hydrogen, alkyl, cycloalkyl, phenyl, a 5-7 membered heteroaryl or heterocycloalkyl having 1-3 heteroatoms and the optional double bond represented by the dotted line is present or R11 and R12 together with the carbons to which they are attached, form a 5-10 membered optionally saturated mono or bicyclic cycloalkyl optionally fused to one of a 5 to 7 membered optionally saturated cycloalkyl ring, phenyl, naphthyl, a 5-7 membered heteroaryl having 1-3 heteroatoms, a 5-7 membered heterocycloalkyl having 1 or 2 heteroatoms or R11 and R12 together with the carbons to which they are attached form a 5-10 membered optionally saturated mono-or bicyclic heterocycloalkyl having 1-2 heteroatoms optionally fused to one of a 5-7 membered mono or bi-cyclic heteroaryl having 1-3 heteroatoms, a 5-7 membered optionally saturated cycloalkyl ring, a phenyl or naphthyl ring and the dotted line represents an optional double bond the heteroatoms are selected from N, N R9, S and O and n is 0 to 2 An intermediate compound has the formula II or III wherein: R6 and R7 are independently, hydrogen, alkyl, -CN, or -CCH; R8 is as defined above and J is fluorine, bromine, chlorine, 1,2,4-triazolyl, benzotriazolyl or imidazolyl. The compounds are useful for treating rheumatoid arthritis, graft rejection, cachexia, inflammation, fever, insulin resistance, septic shock, congestive heart failure, inflammatory disease of the central nervous system, inflammatory bowel disease or HIV infection.
Patent NZ-513530-A (NZ)
Title: Filter device for coffee or the like, the container being foldable into a compact state
Inventor: KATAOKA GEORGE
IPC: A47J31/06
Filed: 2001-08-13
Abstract: A filter device for coffee or the like comprising: a container body (1) consisting of an open frame (2) formed of sheet material having predetermined rigidity, and a blind-end frame (3), including an annular bottom member (6), being joined with the open frame (2) to be foldable into the open frame (2), the blind-end frame (3) being formed of sheet material having predetermined flexibility; and a filter chamber (9) for enclosing substance (8) to be extracted being mounted with a filter (12) between on the annular bottom member (6), wherein the blind-end frame (3) together with the filter chamber (9) is foldable into the open frame (2).
Patent NZ-515263-A (NZ)
Title: Container and method
Inventor: GUALTIERI DOMENICO
IPC: B65D77/20
Filed: 2001-11-02
Abstract: A container moulded from a thermoplastic material for enclosing food product firstly includes a tray (10) having a substantially planar base portion (1) for supporting the product and a rim portion (11) defining the periphery of the tray. There is also a cover (20) adapted to engage and fasten with the rim portion of the tray to securely enclose the product. The rim portion includes a wall member that is upstanding (12) from the base portion of the tray, which includes connection means for engagement of the cover to the tray. The connection means includes a region of the upstanding wall member that is of greater stiffness than the region of the wall member immediately adjacent to the base portion of the tray.
Patent NZ-515837-A (NZ)
Title: Needle-less luer activated medical connector
Inventor: BONALDO JEAN M
IPC: A61M25/00
Filed: 1999-06-01
Abstract: A needle-less flowing connector (10) includes a rotatable Luer housing (20), a Luer valve actuator (30), and a valve element (40) having a fluid passageway (44) which extends from an axially aligned end to an off center positioned end (48). Inter-engaged fingers (27), and grooves (47) prevent rotation of the valve element (40) with respect to the housing (20). An annular bulge (39), and groove (29) prevent withdrawal of the valve actuator (30) from the housing (20). An inter-engaged extending finger (25), and diametrically spaced grooves (35) position the valve in an open or closed position within the housing. A swabbing elastomeric stopper (80) is affixed over the open female Luer end of the valve actuator (30) to provide a safety seal against back flow of bodily fluid when a flow line is disconnected. The stopper (80) may be configured to provide a single or double seal.
Patent NZ-516325-A (NZ)
Title: (R)-3-hydroxy-3-(2-phenylethyl) hexanoic acid and salts thereof
Inventor: GAGE JAMES R
IPC: C07C69/608
Filed: 1998-09-03
Abstract: A compound (R)-3-hydroxy-3-(2-phenylethyl)-hexanoic acid and salts thereof, wherein the salts are selected from the group consisting of (1R,2S)-norephedrine, (1S,2R)-norephedrine, (R)-2-amino-2-phenylethanol, (S)-2-amino-2-phenylethanol, (R)-1-phenylethylamine and (S)-1-phenylethylamine are described.
Patent NZ-519086-A (NZ)
Title: Solid preparation
Inventor: IWATA MOTOKAZU
IPC: C07D209/16
Filed: 2000-11-24
Abstract: A crystal of [3-[(2R)-[[(2R)-[3-chlorophenyl)-2- hydroxyethyl]-amino]propyl]-1H-indol-7-yloxy]acetic acid, which shows characteristic diffraction peaks at angles (2è) of 5.9°, 17.9°, 20.5° and 24.0° in the X-ray diffraction pattern, and has a particle size of not larger than 100 ìm at the cumulative weight distribution value of 50% and not larger than 200 ìm at the cumulative weight distribution of 95%. The crystals are used in pharmaceutical preparations as â3-adrenergic receptor agonists, for the treatment of diabetes mellitus and obesity.
Patent NZ-524435-A (NZ)
Title: Financial transaction system
Inventor: CHAMBERLIN JOHN
IPC: G06Q20/00
Filed: 2001-03-05
Abstract: A wireless financial transaction system for providing banking and financial services comprises: (a) a financial data network utilizing a predetermined data security protocol for receiving and transmitting user financial data; (b) a transaction management system in communication with said financial data network for executing secure financial service transactions through said financial data network in accordance with the predetermined data security protocol in response to user service requests and (c) a wireless communication device for wirelessly transmitting and receiving user service requests, the user service requests being processed by said transaction management system using financial data retrieved from said financial data network. The transaction system receives the user service request in a first encryption standard and submits at least a portion of the data from the user service request to said financial data network in a second encryption standard.
Patent NZ-525804-A (NZ)
Title: Identification of analytes by their two dimensional resolution via adsorption under a plurality of selectivity conditions
Inventor: HUTCHENS T WILLIAM
IPC: G06F19/00
Filed: 2001-11-12
Abstract: A method for identifying analytes that is differentially present in a first and second biological sample comprising the steps of: a) selecting a plurality of different selectivity conditions to which the first and second samples will be exposed, wherein (i) each selectivity condition is defined by an adsorbent and an eluant; (ii) each different selectivity condition comprises the same adsorbent and the same or different eluant; and (iii) exposing a sample to a selectivity condition comprises contacting a sample with an adsorbent bound to a substrate and washing the adsorbent with an eluant to allow retention of analytes in the sample by the adsorbent; b) detecting analytes in the first sample by (i) exposing the first sample, in parallel, to each of the different selectivity conditions, and (ii) detecting analytes retained by the adsorbents by desorption spectrometry comprises desorbing and ionizing the analyte from the adsorbent with an energy source and detecting the desorbed and ionized analytes with a detector; c) detecting analytes in the second sample by (i) exposing the second sample, in parallel, to each of the different selectivity conditions, and (ii) detecting analytes retained by the adsorbents by desorption spectrometry; and d) comparing the analytes detected in the first biological sample with analytes detected in the second biological sample to identify analytes that are differentially present in the first and second biological sample. The method is suitable for retentate chromatography. It provides a unified analyte detection and functional analysis capability for biology and medicine that is characterised by a single, integrated operating system for the direct detection of analyte expression patterns associated with gene function, protein function, cell function, and the function of whole organisms. (62) Divided out of 515411
Patent NZ-529551-A (NZ)
Title: 3,4-DI-substituted cyclobutene-1,2-diones as CXC- chemokine receptor ligands
Inventor: TAVERAS ARTHUR G
IPC: C07D307/56
Filed: 2002-04-15
Abstract: Disclosed is a compound of the formula (I), wherein A is selected from the group consisting of compounds such as (a), (b) and (c); and B is the compound of formula (II). The use of the compound is described to be for the manufacture of a medicament for treating a chemokine-mediated disease wherein the chemokine binds to a CXCR2 and/or CXCR1 receptor in a mammal. the chemokine mediated disease is selected from conditions such as acne, asthma, arthritis and inflammatory bowel disease.