baber/WOPTO huggingface dataset:
Patent CA-2646163-A1 (CA)
Title: Sels de 3,7-diamino-10h-phenothiazine et utilisation correspondante
Inventor: RICKARD JANET ELIZABETH
IPC: C07D279/20
Filed: 2007-03-28
Abstract: L'invention concerne, de manière générale, des composés de phénothiazine, et plus particulièrement, certains composés de phénothiazine soumis à une réduction stable, spécifiquement, certains composés de,7 diamino-10H-phénothiazine (DAPTZ) représentés par la formule (I): dans laquelle R1 et R9 sont indépendamment sélectionnés dans: -H; C1-4alkyle; C2-4alcényle et C1-4alkyle halogéné; chacun de R3NA et R3NB est indépendamment sélectionné dans: -H; C1-4alkyle; C2-4alcényle; et C1-4alkyle halogéné; chacun de R7NA et R7NB est indépendamment sélectionné dans: -H; C1-4alkyle; C2-4alcényle; et C1-4alkyle halogéné; et chacun de HX1 et HX2 représente indépendamment un acide protique; l'invention concernant en outre des sels, solvates et hydrates de qualité pharmaceutique correspondants. Ces composés sont utiles comme médicaments, par exemple, dans le traitement des tauopathies, notamment la maladie d'Alzheimer, ainsi que comme promédicaments pour les médicaments à base de thioninium oxydé correspondants (par exemple, le chlorure de méthythioninium chloride, MTC).
Patent CA-2646617-A1 (CA)
Inventor: FYKE STEVEN H
IPC: H04M1/72454
Filed: 2008-12-12
Abstract: A portable electronic device includes a housing, a display device exposed by the housing, an input device for receiving user-input, a plurality of sensors on the housing for detecting touches on the portable electronic device, and functional components housed in the housing. The functional components include a memory device and a processor operably connected to the sensors, the display device the input device, and the memory device.
Patent CA-2649866-A1 (CA)
Title: Wlan and wwan connection migration methods and apparatus
Inventor: TODD TERENCE D
IPC: H04M11/06
Filed: 2007-04-27
Abstract: Intra-enterprise wireless handset (WH) calls between WHs operating in a wireless local area network (WLAN) are established directly between the WHs via a call connection that is maintained within the LAN without being routed through the cellular network (CN). This eliminates the cost of placing and maintaining calls through the CN for intra-enterprise calls, and also enables use of capabilities that are available in the enterprise telecomm equipment. Upon detection of a trigger condition, if and when it is more likely that a complete vertical handover (VHO) may be needed, the call connection between the WHs in the LAN is replaced by one that is routed through the CN. Thereafter, a VHO may occur (if at all) upon detection of a radio handover condition.
Patent CA-2650640-A1 (CA)
Inventor: EBLE RAYMOND C
IPC: B65D23/00
Filed: 2009-01-22
Abstract: A device and container for improving the connection of a lid to a container by providing for a shelved container neck. The neck includes a shelved land on the top surface of the container neck which provides for an increased radial thickness to the top surface of the container neck.
Patent CA-2650805-A1 (CA)
Inventor: NANDAN SANTOSH
IPC: C12N1/00
Filed: 2007-05-09
Abstract: A therapeutic agent for administration to a bacterium or to the environment thereof which agent comprises synergistically effective amounts of (i) an RNA polymerase inhibitor and (ii) an ALS enzyme inhibitor.
Patent CA-2650863-A1 (CA)
Title: Machine de forage avec tige de forage a carrousel et chargeur a tube de protection
Inventor: COMACCHIO PASQUALINO
IPC: E21B19/14
Filed: 2006-05-09
Abstract: L'invention concerne une machine de forage, destinée en particulier à être utilisée sur terrain non rocheux et comprenant un corps de machine équipé d'un mât (M) doté d'une ou de plusieurs têtes fonctionnelles rotatives (R1, R2) et de mandrins (Q1, Q2) permettant la rotation vers le bas des modules de tige de forage (A) et/ou des modules de tube de protection (T), un chargeur à carrousel (C) des modules de tige de forage (A), chacune introduite dans un module de tube de protection (T) et transportée sur une plate-forme de coulissement (S).
Patent CA-2651266-A1 (CA)
Inventor: JOHNSTON GABRIEL A
IPC: A61B17/16
Filed: 2007-05-01
Abstract: A system for use in a surgical procedure comprising a pneumatic instrument having an inlet and an outlet, a tank fluidly coupled to the inlet of the pneumatic instrument, wherein the tank provides pressurized helium gas to power the pneumatic instrument, and a compressor fluidly coupled to the outlet of the pneumatic instrument. The compressor receives the helium gas exhausted from the pneumatic instrument and compresses the exhausted helium gas to supply the tank with pressurized helium gas.
Patent CA-2653847-A1 (CA)
Title: Apparatus and methods for the delivery of medicaments to the respiratory system
Inventor: POWER JOHN SYLVESTER
IPC: A61M11/02
Filed: 2001-05-04
Abstract: An apparatus (1) for the delivery of medicament to the respiratory system of a patient comprises a medication cup (2), an aerosol generator (3), a housing (4) for the aerosol generator (3), a liquid supplier (5) and a connector (6). Liquid medication placed within the medication cup (2) is delivered by the liquid supplier (5) to the generator (3). The aerosol generated is passed through the housing (4) into the connector (6). A gas, such as air, is d elivered into a gas inlet (61) of the connector (6), for example by pumping the gas from a ventilator (70). Within the connector (6) the gas entrains the aerosol therein, and the air with entrained medication is delivered through an outlet (62).
Patent CA-2655734-A1 (CA)
Inventor: PERKOVICH MICHAEL P
IPC: B23B51/04
Filed: 2007-06-20
Abstract: Apparatus (10) and method for using a portable tool (20) for assisting the making of holes in pipes (12) to prepare for interconnected branch or cross lines. The apparatus includes a guide member (24) and a plurality of bushings (52, 52a, 52b, Fig. 5) able to accommodate a plurality of hole saws (22, 22a, 22b, Fig. 5) of varying diameters. The apparatus includes a stop member (46) to prevent inadvertent sawing of the opposite internal pipe wall. The apparatus includes a drill bit (40a, Fig. 4) able to span the internal diameter of the pipe to create a pilot hole (50) to mark the centerline of the cross hole to be sawed.
Patent CA-2658422-A1 (CA)
Inventor: SINGH RAVI
IPC: G06K7/10
Filed: 2007-03-16
Abstract: The described embodiments relate generally to devices, methods and systems for managing access to a memory card, such as a smart card, by a plurality of accessing devices. Certain embodiments relate to a smart card reader (SCR) for managing access to a smart card by a plurality of accessing devices. The SCR comprises : a processor; a channel manager responsive to the processor for interfacing with the smart card; and a communication interface responsive to the channel manager for communicating with the plurality of accessing devices.
Patent CA-2658991-A1 (CA)
Title: Genomics based targeted advertising
Inventor: LESCHLY JACOB
IPC: G06Q30/00
Filed: 2007-07-27
Abstract: A method for targeted advertising comprising obtaining genomic data of an individual, correlating the genomic data to a personal trait of said individual and addressing advertising material to said individual based on said personal trait.
Patent CA-2659529-A1 (CA)
Inventor: YANG LILI
IPC: A61K35/76
Filed: 2007-07-23
Abstract: Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus envelope comprises a DC-SIGN specific targeting molecule. The methods and related compositions can be used to treat patients suffering from a wide range of conditions, including infection, such as HIV/AIDS, and various types of cancers.
Patent CA-2662242-A1 (CA)
Title: Benzo-fused compounds for use in treating metabolic disorders
Inventor: DRANSFIELD PAUL JOHN
IPC: C07D239/26
Filed: 2007-09-06
Abstract: The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula I: where the definitions of the variables Q, L1, ~, L2, M, X, L3, and A are provided herein. The present invention also provides compositions that include, and methods for using, the compounds in preparing medicaments and for treating metabolic disorders such as, for example, type II diabetes.
Patent CA-2663285-A1 (CA)
Title: A method of improving membrane bioreactor performance
Inventor: COLLINS JOHN H
IPC: C02F3/12
Filed: 2007-09-05
Abstract: Cationic polymers having a molecular weight greater than about 200,000 can be added to the activated sludge in an MBR for industrial wastewater treatment for reasons, which include: conditioning the activated sludge; improving flux through a membrane in the MBR; reducing fouling of the of the membrane in the MBR; and reducing foaming of the activated sludge in the MBR.
Patent CA-2663954-A1 (CA)
Inventor: CASHMAN JOHN R
IPC: A61K31/222
Filed: 2007-09-19
Abstract: Disclosed are methods for identifying individuals suffering from a CNS disorder (including Alzheimer's Disease, behavioral disorders, and the like) that could be treated with a CNS drug with greater therapeutic efficacy and lower side effects and the compounds useful for such treatment. Also disclosed are methods for predicting the efficacy of a drug candidate for the treatment of a CNS disorder. The technology is also applicable to drug discovery for use in animal models of neurodegenerative diseases.
Patent CA-2664638-A1 (CA)
Inventor: HAWTHORNE MICHAEL J
IPC: B61L27/00
Filed: 2007-10-15
Abstract: A method of optimizing marshalling rail cars into a train at a site and includes determining the track configuration at the site; determining location on the tracks of cars to be marshaled; determining characteristics of the cars to be marshaled; and determining marshalling rules. A calculation is performed to determine an optimum sequence of moves to marshal the cars into a train from the determined track configuration, location on the tracks of cars, characteristics of the cars and the marshalling rules. The resulting sequence is outputted.
Patent CA-2665108-A1 (CA)
Title: Clay-based hemostatic agents and devices for the delivery thereof
Inventor: LO DENNY
IPC: A61L15/16
Filed: 2007-07-20
Abstract: A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate , and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the subs trate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic spo nge causes at least a portion of the hemostatic material to come into contac t with blood through the release agent and through the substrate.
Patent CA-2669158-A1 (CA)
Inventor: STIEHL JURGEN
IPC: A61P35/00
Filed: 2007-11-03
Abstract: The present invention relates to the polymorph II of 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide, to processes for its preparation, to pharmaceutical compositions comprising it and to its use in the control of disorders.
Patent CA-2671876-A1 (CA)
Inventor: YIN CAIFANG
IPC: D21C9/14
Filed: 2007-12-12
Abstract: This invention relates to an improved bleaching process for bleaching pulp comprising at least one bleaching stage which comprises treating a hardwood pulp with a bleaching agent comprising CIO2 in the presence of a weak base such as, for example, Mg(OH)2 preferably at pH from about 3.5 to about 6.5. The invention is also relates a bleaching process for bleaching pulp having two or more bleaching stages, at least one of which and preferably two of which comprises treating a pulp with a bleaching agent comprising ClO2 in the presence of a weak base such as, for example, Mg(OH)2 preferably at pH from about 3.5 to about 6.5.
Patent CA-2672379-A1 (CA)
Title: Prepolymer mixture containing silyl groups and use thereof
Inventor: KOHL MATTHIAS
IPC: C09J183/00
Filed: 2007-07-19
Abstract: A description is given of one-component, moisture-curing adhesive/sealant compositions comprising mixtures of at least one silane-functional polyoxyalkylene prepolymer and at least one silane-functional polyolefin. These compositions may optionally further comprise non-polar plasticizers and also catalysts, fillers and adhesion promoters. Adhesive/sealant compositions of this kind feature excellent adhesion to plastics substrates and also to painted surfaces, the adhesion being retained even after storage under damp conditions.
Patent CA-2673602-A1 (CA)
Title: Pump and nozzle liquid flow control system
Inventor: BONNER MARK
IPC: F04B33/00
Filed: 2005-09-08
Abstract: This invention disclosed herein relates to a pump apparatus for use with a liquid container for transferring liquid from a liquid container. It comprises a pump means comprising a manually-operable pump for pumping liquid and formed with a pump chamber through which liquid can be pumped by the pump. It also has an inlet opening for receiving liquid into the pump chamber and an outlet opening for dispensing liquid out of the pump chamber when liquid is pumped through the chamber using the pump. There is a coupling means for mounting the pump means to the opening of a liquid container to permit the gravitational flow of liquid into the pump chamber through the inlet opening when the mounted pump means is placed on ground level and the pump pumped.
Patent CA-2673797-A1 (CA)
Inventor: STOCCO LOUIS P
IPC: C04B38/10
Filed: 2007-12-20
Abstract: A gypsum slurry includes calcium sulfate hemihydrate, water and calcium sulfate dihydrate, where the calcium sulfate dihydrate is added downstream of the mixer. In an optional embodiment, the a gypsum slurry includes calcium sulfate hemihydrate, a polycarboxylate dispersant, water and coated calcium sulfate dihydrate. In this case, the hydrophilic, dispersible coating is selected to serve as a modifier to enhance the ability of the dispersant to fluidize the gypsum slurry.
Patent CA-2674586-A1 (CA)
Title: Adjustable compression staple and method for stapling with adjustable compression
Inventor: KLINE KOREY ROBERT
IPC: B21F45/24
Filed: 2008-01-11
Abstract: A compression-self-adjusting staple includes a substantially U-shaped sta ple body and a compression device. The staple body has a bridge and two legs extending from the bridge at an angle thereto. Each of the legs has a base end integral with die bridge and a deformabie distal end defining a stapling point shaped to pierce material to be stapled. The compression device is at least partly disposed between the legs and has a bias portion with a compre ssion surface movably disposed between the legs and a compression resistor c onnected to the bridge and to the compression surface and formed to resist m ovement of the compression surface towards the bridge with a force.
Patent CA-2675287-A1 (CA)
Inventor: OTSUBO TOSHIFUMI
IPC: A61F13/49
Filed: 2007-11-16
Abstract: Disposable underpants type diapers in which a pocket for containing excrement is aligned easily with an external genitalia and an anus are produced continuously. A first web (201) where diaper basic bodies are continuous in their width direction is supplied in the machine direction MD. A second web where sheet-like members being fixed to the inner surface side of an inseam area in order to form pockets are continuous in their width direction is supplied in the machine direction MD and folded in the cross direction CD, and then the edge portions are bonded locally at the same pitch as the width of the diaper basic body, thus obtaining a third web (203) having a joint (135). The third web (203) is superimposed on the first web (201) such that the joint (135) is located in the center of the diaper basic body in the width direction and then they are bonded on the opposite side edge portions of the inseam area, thus obtaining a first compound web (301). The first compound web (301) is bent in the cross direction CD and the opposite side edge portions of the inseam area are bonded to each other, an almost semicircular web piece is clipped from between the diaper basic bodies to form a bond area along a cut line extending in the cross direction CD, and then it is cut at the cut lineto obtain individual underpants type diapers.
Patent CA-2677989-A1 (CA)
Inventor: MAPELLI LUIGI
IPC: A61K9/50
Filed: 2008-02-20
Abstract: Compositions of the present invention, comprising at least one digestive enzyme (e.g., pancrelipase) are useful for treating or preventing disorders associated with digestive enzyme deficiencies. The compositions of the present invention can comprise a plurality of coated particles, each of which is comprised of a core coated with an enteric coating comprising at least one enteric polymer and 4-10% of at least one alkalinizing agent, or have moisture contents of about 3% or less, water activities of about 0.6 or less, or exhibit a loss of activity of no more than about 15% after six months of accelerated stability testing.
Patent CA-2678401-A1 (CA)
Inventor: RILEY JOHN G
IPC: G01N33/44
Filed: 2007-02-22
Abstract: A process for purification of water soluble polymers is provided. A polymer of interest can be separated from a mixture of polymers, provided the polymer of interest differs from other polymers in the mixture in the number of reactive terminal groups. The process involves derivatizing polymers at the reactive terminal groups with a derivatizing molecule, bearing either (i) two or three cationic or anionic ionizable groups, and a group capable of covalent bonding to the reactive terminal groups or (ii) three or four ionizable groups, at least one of which is capable of covalent bonding to the reactive terminal groups; followed by ion exchange. The process allows removal of PEG from MPEG, and can be used for polymers having an average size greater than 9,000 Da Derivatization may be reversible in order to allow re-use of recovered contaminant polymers.
Patent CA-2678958-A1 (CA)
Title: Heterocyclic aspartyl protease inhibitors
Inventor: WANG LINGYAN
IPC: C07D409/04
Filed: 2008-02-20
Abstract: Disclosed are compounds of the formula (I) or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein W is a bond, -C(=S)-, -S(O)-, -S(O)2-, -C(=O)-, -O-, -C(R6)(R7)-, -N(R5)- or -C(=N(R5))-; X is -O-, -N(R5)- or -C(R6)(R7)-; provided that when X is -O-, U is not -O-, -S(O)-, -S(O)2-, -C(=O)- or -C(=NR5)-; U is a bond, -S(O)-, -S(O)2-, -C(O)-, -O-, -P(O)(OR15)-, -C(=NR5)-, -(C(R6)(R7))b- or -N(R5)-; wherein b is 1 or 2; provided that when W is -S(O)-, -S(O)2-, -O-, or -N(R5)-, U is not -S(O)-, -S(O)2-, -O-, or -N(R5)-; provided that when X is -N(R5)- and W is -S(O)-, -S(O)2-, -O-, or -N(R5)-, then U is not a bond; and R1, R2, R3, R4, R5, R6, and R7 are as defined in the specification; and pharmaceutical compositions comprising the compounds of formula (I). Also disclosed is the method of inhibiting aspartyl protease, and in particular, the methods of treating cardiovascular diseases, cognitive and neurodegenerative diseases, and the methods of inhibiting of Human Immunodeficiency Virus, plasmepins, cathepsin D and protozoal enzymes. Also disclosed are methods of treating cognitive or neurodegenerative diseases using the compounds of formula I in combination with a cholinesterase inhibitor or a muscarinic m1 agonist or m2 antagonist.
Patent CA-2683960-A1 (CA)
Inventor: WANG LEI
IPC: C12N15/09
Filed: 2008-04-04
Abstract: This disclosure concerns compositions and methods for genetically encoding and expressing prokaryotic tRNAs in eukaryotic cells. In some embodiments, the disclosure concerns methods and compositions for expressing unnatural amino acids in eukaryotic cells using orthogonal tRNA/synthetase pairs. In certain embodiments, the methods involve expressing prokaryotic tRNA/synthetase pairs in eukaryotic cells, for instance mammalian cells or yeast cells (such as those that are NMD-deficient), under the control of a pol III promoter, for instance a type-3 pol III promoter or an internal leader promoter. Also provided are cell lines that are NMD- deficient and methods of increasing the efficiency of UAA incorporation in a cell that include de-activating the NMD pathway in the cell.
Patent CA-2684353-A1 (CA)
Title: Identifying implicit services links using service usage information
Inventor: NIGUL LEHO
IPC: G06F17/00
Filed: 2009-11-04
Abstract: An illustrative embodiment of a computer-implemented process for identifying implicit services links, using service usage information, in service registries and repositories. Service registry and repository receives service access information for a service to form received information, creates a services access context object in real time from all received information or a selected subset of received information to form a created services access context object, and stores the created services access context object in a data structure to form a stored services access context object. The computer-implemented process further analyzes a set of stored services access context objects in real time to form a set of results, wherein the results are within a predefined certainty and sends the result to a requester. The set of results comprises a set of implicit soft links determined by usage information in the services access context objects, wherein the implicit soft links are implicit services links.
Patent CA-2685260-A1 (CA)
Inventor: TWIST CYRIL
IPC: B65D65/40
Filed: 2008-04-30
Abstract: Polymeric films having a first layer of polylactic acid, a second layer of polyvinyl alcohol and at least one intermediate layer of a blend of polylactic acid with polyvinyl alcohol and/or starch, the intermediate layer or layers providing adhesion between the polylactic acid layer and the polyvinyl alcohol layer. Such films are environmentally friendly and have good impact strengths which enable them to be used to package relatively heavy loads of fresh produce such as potatoes.
Patent CA-2688961-A1 (CA)
Inventor: CERRETA PIETRANTONIO
IPC: G01M17/00
Filed: 2009-12-21
Abstract: Gripping claws and pairs of arched angular profiles are arranged along the perimeter of a cylindrical surface segment so as to grip the edges of a fuselage panel, closing the opening of a pressurizable chamber.