baber/WOPTO huggingface dataset:
Patent MX-2019004871-A (MX)
Title: Humanized non-human animals with restricted immunoglobulin heavy chain loci.
Inventor: ANDREW J MURPHY
IPC: A01K67/027
Filed: 2014-12-11
Abstract: Mice, embryos, cells, and tissues having a restricted immunoglobulin heavy chain locus and an ectopic sequence encoding one or more ADAM6 proteins are provided, in various embodiments, mice are described that have humanized endogenous immunoglobulin heavy chain loci and are capable of expressing an ADAM6 protein or ortholog or homolog or functional fragment thereof that is functional in a male mouse. Mice, embryos, cells, and tissues having an immunoglobulin heavy chain locus characterized by a single human VH gene segment, a plurality of human DH gene segments and a plurality of human JH gene segments and capable expressing an ADAM6 protein or ortholog or homolog or functional fragment thereof are also provided.
Patent MX-2019005454-A (MX)
Title: Continuously variable transmission.
Inventor: THOMASSY FERNAND A
IPC: F16H15/28
Filed: 2007-03-29
Abstract: A continuously variable transmission (CVT) having a main shaft configured tosupport and position various components of the CVT. Shift cam discs cooperatewith ball-leg assemblies to shift the transmission ration of the CVT. Load camdiscs, a torsion disc, rolling elements, and a hub cap shell are configured togenerate axial force, transmit torque, and manage reaction forces. In one embodiment,a splined input shaft and a torsion disc having a splined bore cooperate to inputtorque into the variator of the CVT. Among other things, various ball axles, axle-ballcombinations, and reaction force grounding configurations are disclosed.In one embodiment, a CVT having axial force generation means at both the inputand output elements is disclosed.
Patent MX-2019006463-A (MX)
Title: Insulin containing pharmaceutical compositions.
Inventor: MATHIAS NORRMAN
IPC: A61K38/28
Filed: 2017-12-15
Abstract: The present invention is in the field of pharmaceutical compositions for the treatment of medical conditions relating to diabetes. More specifically the invention provides pharmaceutical compositions comprising a long-acting acylated derivative of a human insulin analogue, and to the medical use of such compositions for basal insulin administration therapy.
Patent MX-2019006518-A (MX)
Title: An apparatus for constructing foundation pilings.
Inventor: ANDREW CORBIN FULLER
IPC: E02D7/22
Filed: 2017-12-04
Abstract: Apparatus for making foundation pilings includes a lead section with screw threads, at least one extension section, and a bit carried by the first of the extension sections. The bit slides onto the first, lower end of the extension section and is operable to compress the soil laterally to the extension sections and form a lateral groove in the soil. Grout fills the annular region of the hole bored by the apparatus including the grooves for lateral stability. Each extension section is formed to fit into the next one and to be secured to it by lateral bolts. The bolt heads prevent the bit from moving vertically as the lead section advances into the soil. Bits may be added to increase the size of the opening bored.
Patent MX-2019006711-A (MX)
Title: Synthesis of liraglutide.
Inventor: PALLE VENKATA RAGHAVENDRA CHARYULU
IPC: C07K4/00
Filed: 2017-12-09
Abstract: The present invention relates to the efficient solid-phase synthesis of liraglutide represented by Formula-I. The present invention relates to an efficient process for the preparation of liraglutide by sequential coupling employing solid phase approach. It involves sequential coupling of protected amino acids to prepare backbone of liraglutide and upon completion of linear sequence, synthesis was extended from lysine side chain by adding y-glutamic acid and palmitic acid, followed by removal of protective groups, cleavage of the peptide from solid support and purification of crude liraglutide obtained. The present invention also involves the usage of inorganic salts during the coupling, wash with HOBt in DMF solution after Fmoc-deprotection step to suppress the aggregation of peptides and ensure reactions are going for completion, and thus avoid deletion sequences and improve the process yield.
Patent MX-2019006944-A (MX)
Title: Estimating fish size, population density, species distribution and biomass.
Inventor: PROSPERO C NAVAL JR
IPC: G06T7/80
Filed: 2017-12-13
Abstract: A computerized system of performing fish census which otherwise requires high level of domain knowledge and expertise is described. Divers with minimal knowledge of fish can obtain high quality population and species distribution measurement using a stereo camera rig and fish video analyzer software that was developed. The system has two major components: a camera rig and software for fish size, density and biomass estimation. The camera rig consists of a simple stand on which one to four pairs of stereo cameras are mounted to take videos of the benthic floor for a few minutes. The collected videos are uploaded to a server which performs stereo analysis and image recognition. The software produces video clips containing estimates of fish size, density and species biodiversity and a log report containing information about the individual fishes for further end user analysis.
Patent MX-2019010125-A (MX)
Title: Process for removing contaminants during the separation of copper and molybdenum.
Inventor: REYES BAHENA JUAN LUIS
IPC: B03D1/001
Filed: 2019-08-16
Abstract: The present invention discloses a process for removing contaminants during the separation of copper and molybdenum. Also, it possesses the advantage of reducing pollutants, such as metallic sulfides and gangue minerals, thus obtaining a molybdenum concentrate free of contaminants.
Patent MX-2019013532-A (MX)
Title: Method for using lipase enzymes for cleaning.
Inventor: ESPER CLAUDIA
IPC: C11D3/386
Filed: 2018-05-10
Abstract: A method for removing a stain from a surface using lipase enzymes, and a formulation comprising a lipase enzyme.
Patent MX-2020002646-A (MX)
Title: Enpp1 inhibitors and their use for the treatment of cancer.
Inventor: SMITH MARK
IPC: C07D471/00
Filed: 2018-09-07
Abstract: Compounds, compositions and methods are provided for the inhibition of ENPP1. Aspects of the subject methods include contacting a sample with a ENPP1 inhibitor to inhibit cGAMP hydrolysis activity of ENPP1. In some cases, the ENPP1 inhibitor is cell impermeable. Also provided are compositions and methods for treating cancer. Aspects of the methods include administering to a subject a therapeutically effective amount of a ENPP1 inhibitor to treat the subject for cancer. In certain cases, the cancer is a solid tumor cancer. Also provided are methods of administering radiation therapy to a subject either before or after administering an ENPP1 inhibitor. The radiation therapy can be administered at a dosage and/or frequency effective to reduce radiation damage to the subject. In certain cases, the method is performed in combination with a chemotherapeutic agent, or a checkpoint inhibitor, or both.
Patent MX-2020004742-A (MX)
Inventor: WALLER AMOS KENT
IPC: B66F9/06
Filed: 2018-11-02
Abstract: Se divulga un sistema de soporte de colocación lateral para soportar un vehículo industrial en una posición horizontal. El sistema de soporte de colocación lateral incluye un soporte de colocación lateral acoplado de manera removible a una porción del extremo proximal del vehículo industrial, el soporte de colocación lateral incluye al menos una rueda para mover el sistema de soporte de colocación lateral con el vehículo industrial soportado en el mismo mientras el vehículo industrial está en la posición horizontal. El soporte de colocación lateral soporta la porción del extremo proximal del vehículo industrial cuando el vehículo industrial está en una posición horizontal y permite que el sistema de soporte de colocación lateral y el vehículo industrial rueden sobre dicha al menos una rueda del soporte de colocación lateral. El sistema de soporte de colocación lateral también puede incluir un soporte de apoyo para soportar un extremo distal del vehículo industrial mientras el vehículo está en la posición horizontal.
Patent MX-2020006052-A (MX)
Title: High-carbon hot-rolled steel sheet and production method for same.
Inventor: SAITO HAYATO
IPC: C22C38/00
Filed: 2016-01-07
Abstract: Provided is a high-carbon hot-rolled steel sheet, the material of which is steel to which B has been added, which exhibits consistently excellent hardenability even when annealing is conducted in a nitrogen atmosphere, and which has excellent workability, such that prior to the hardening process, total elongation at an HRB of 83 or less is 30% or greater, or total elongation at an HRB of 75 or less is 30% or greater. The high-carbon hot-rolled steel sheet contains C: 0.20%-0.53%, Si: 0.10% or less, Mn: 0.50% or less, P: 0.03% or less, S: 0.010% or less, sol. Al: 0.10% or less, N: 0.0050% or less, and B: 0.0005%-0.0050%, and further contains a total of 0.002%-0.030% of one or more of the elements Sb, Sn, Bi, Ge, Te, and Se, and has a microstructure comprising ferrite and cementite, in which, when C is more than 0.40% but not more than 0.53%, the cementite density within the ferrite grains is 0.15/Î¼m<sup>2</sup> or fewer, or when C 0.20%-0.40%, the cementite density within the ferrite grains is 0.10/Î¼m<sup>2</sup> or fewer.
Patent MX-2020006116-A (MX)
Title: Combination therapy of tumor targeted icos agonists with t-cell bispecific molecules.
Inventor: FAUTI TANJA
IPC: C07K16/40
Filed: 2018-12-20
Abstract: The present invention relates to agonistic ICOS-binding molecules comprising at least one antigen binding domain that binds to a tumor-associated antigen and their use in combination with T-cell bispecific molecules in the treatment of cancer, the agonistic ICOS-binding molecules as such, pharmaceutical compositions comprising these molecules, and methods of using the same.
Patent MX-2021002648-A (MX)
Title: Process for the preparation of methanol.
Inventor: HULTQVIST MICHAEL
IPC: C25B15/08
Filed: 2019-08-28
Abstract: Process for the preparation of a methanol product comprising the steps of a) providing a first process stream consisting essentially of carbon dioxide; b) providing a second process stream consisting of hydrogen by electrolyzing water in an electrolysis unit; c) mixing the first and second process in amount to obtain a methanol synthesis gas with a mole ratio of H2 and CO2 of between 2.5 and 3.5; d) catalytic converting the methanol synthesis gas into raw methanol in at least one methanol reactor; e) purifying the raw methanol in a distillation unit; and recovering waste heat generated in the electrolysis unit in step (b) by transferring the waste heat to a circulating heat transfer medium by indirect heat exchange with the waste heat and by indirect heat exchange of the heated heat transfer medium with steam used for the distillation of the raw methanol, wherein the heated transfer medium is compressed upstream the indirect heat exchange with steam.
Patent MX-2021003156-A (MX)
Title: Treatment for non-alcoholic fatty liver disease.
Inventor: J LI Chiang
IPC: A61K31/437
Filed: 2019-09-18
Abstract: The invention provides novel methods of treating or preventing nonalcoholic fatty liver disease (NAFLD) including non-alcoholic steatohepatitis (NASH) in a mammal including a human.
Patent MX-2021006168-A (MX)
Title: Link device for conversion, interconnection, and interpretation of "can" and "lin" automotive protocols with graphic user interface.
Inventor: QUIROZ HERNÁNDEZ NICOLÁS
IPC: G06F3/038
Filed: 2021-05-26
Abstract: The present invention relates to a link device for the conversion, interconnection, and interpretation of automotive "CAN" and "LIN" protocols, including an FR-4 card, a microcontroller, an external oscillator crystal, and a graphical user interface.
Patent MX-2021008712-A (MX)
Title: Heterocyclic derivatives.
Inventor: HEINRICH TIMO
IPC: A61P29/00
Filed: 2020-01-20
Abstract: Compounds of the formula (I): Q1-Q2-Q3, in which Q1, Q2 and Q3 have the meanings indicated in Claim 1, degrade target proteins, and can be employed, inter alia, for the treatment of diseases such as cancer, multiple sclerosis, cardiovascular diseases, central nervous system injury and different forms of inflammation.
Patent MX-2021009057-A (MX)
Title: Blast protection wall including cementitious panel.
Inventor: POSPISIL FRANK
IPC: E04B2/74
Filed: 2020-02-05
Abstract: A wall for a building that includes a framed wall structure including a top support, a bottom support, and opposing side supports connected together, and at least one intermediate support attached to the top support and the bottom support, and a blast panel made of a cementitious material attached to the framed wall structure.
Patent MX-2021011103-A (MX)
Title: Wetness indicator free from halogen-containing species.
Inventor: SECRIST KIMBERLY E
IPC: A61F13/42
Filed: 2020-03-12
Abstract: A hot melt wetness indicator comprising an adhesive base composition utilizing a halogen-free species, namely nitrazine yellow, to trigger color change in hygiene articles, such as disposable diapers, to serve as moisture or wetness indicator upon insult. In some embodiments of the invention, the wetness indicator turns from yellow to purple.
Patent MX-2021012638-A (MX)
Title: Bicyclic compounds.
Inventor: KONRADI ANDREI W
IPC: A61P35/00
Filed: 2020-04-15
Abstract: Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for treating cancers. Specific cancers include those that are mediated by YAP/TAZ or those that are modulated by the interaction between YAP/TAZ and TEAD.
Patent MX-2021014000-A (MX)
Title: Triamcinolone acetonide-loaded liposomes topical ophthalmic formulations for prevention of macular thickening and its associated visual outcomes after lens surgery.
Inventor: HSIAO JANE H
IPC: A61K9/00
Filed: 2020-05-05
Abstract: The invention relates to triamcinolone acetonide-loaded liposomes topical ophthalmic formulations for prevention of macular thickening and its associated visual outcomes after lens surgery. The liposomal formulation comprises thermodynamically self-forming liposomes which are useful in topical form to treat posterior segment diseases of the eye.
Patent MX-2021014796-A (MX)
Title: Compounds for chromatographic separation of rare earth elements and s-, p-, d- metals, method of separation, and use thereof.
Inventor: POLASEK MILOSLAV
IPC: C07B59/00
Filed: 2020-05-28
Abstract: The present invention relates to compounds of general formula (I), wherein - X is selected from a group consisting of H; C1 to C6, alkyl; halogen (F, Cl, Br or I); Y is selected from a group consisting of nitrogen; N-oxide; Z1, Z2, Zm, wherein m is 1 or 2, are independently selected from the group consisting of -CH2-CH2- and -CH2-CH2-CH2-; A, Am, wherein m is 1 or 2, are independently selected from H; -CH2COOH; -CH2C(O)NH2; -CH2P(O)(OH)2, and - n is 1 or 2; R1, R2, R3 are independently H; C1 to C6, alkyl; C1 to C6 alkyloxy; C6 to C10 aryloxy; benzyloxy; C1 to C6 alkylthio; C6, to C10 arylthio; F; Cl; Br; I; OH; SH; NH2; C1 to C6, alkylamino; di(C1 to C6, alkyl)amino; C1 to C6 acylamino; di(C1 to C6 acyl) amino; C6 to C10 arylamino; di(C6 to C10 aryl)amino; CN; OH; nitro; COORn, C(O)NHRn, C(O)N(Rn)2, wherein Rn is independently H or C1 to C10 alkyl or C6, to C10 aryl; and/or neighboring two of R1, R2, R3 together with neighboring two carbon atoms of the aromatic cycle form a six-membered ring, optionally substituted with one or more substituents independently selected from the group consisting of OH, SH, CF3, F, Cl, Br, I, C1 to C6, alkyl, C1 to C6, alkyloxy, C1 to C6 alkylthio, NH2, C1 to C6 alkylamino, di(C1 to C6 alkyl)amino, NO2, COOH, COORn, C(O)NHRn, C(O)N(Rn)2, wherein Rn is independently H or C1 to C10 alkyl or C6 to C10 aryl; with the proviso that when n is 2 and all of Z1, Z2, Zm are -CH2-CH2-, then A is not -CH2COOH; for chromatographic separation of rare earth elements and/or s-, p- and d-block metals, as well as to the method of the separation of rare earth elements.
Patent MX-2021015228-A (MX)
Title: Methods and compositions for improving outcomes of cancer patients.
Inventor: VOLK MICHAEL A
IPC: A61K31/185
Filed: 2020-06-12
Abstract: This disclosure provides compositions and methods for improving outcomes in cancer patients. Specifically, a method of preventing, alleviating, or treating cancer comprising administering an effective amount of a composition to a subject in need thereof, wherein the composition comprises: at least one pharmaceutical grade acid and at least one pharmaceutical grade pH buffering agent in a sterile aqueous solution, wherein the concentration of the pharmaceutical grade acid and the pharmaceutical grade pH buffering agent in the buffer solution is sufficient to provide a total titratable acid content between 60 mmol/L and 3000 mmol/L when administered to a subject, and wherein the selection of the pharmaceutical grade acid and the pharmaceutical grade pH buffering agent is effective to provide a buffer solution pH of between 4.0 and 7.7.
Patent MX-2021015288-A (MX)
Title: Methylthioninium for use in the treatment of synaptopathies.
Inventor: HARRINGTON CHARLES ROBERT
IPC: A61K31/5415
Filed: 2020-06-29
Abstract: The present invention relates generally to methods and materials for treating synaptopathies, based on the use of Leuco-methylthioninium acid salts, which are disclosed herein to increase synaptophysin levels in various brain regions at therapeutically relevant doses both in animal models of neurodegenerative disease, and in normal animals.
Patent MX-2022000028-A (MX)
Title: Image encoding/decoding method and apparatus using maximum transform size setting for chroma block, and method for transmitting bitstream.
Inventor: LI LING
IPC: H04N19/122
Filed: 2020-06-24
Abstract: Provided are an image encoding/decoding method and apparatus. An image decoding method, performed by an image decoding apparatus, according to the present disclosure, may comprise the steps of: splitting an image to obtain the current block; determining a prediction mode of the current block; if the prediction mode of the current block is an intra prediction mode, then generating an intra prediction block for the current block; generating a residual block of the current block; and reconstructing the current block on the basis of the prediction block and the residual block.
Patent MX-2022001849-A (MX)
Title: Rna-guided nucleases and active fragments and variants thereof and methods of use.
Inventor: BOWEN TYSON D
IPC: C12N15/10
Filed: 2020-08-11
Abstract: Compositions and methods for binding to a target sequence of interest are provided. The compositions find use in cleaving or modifying a target sequence of interest, visualization of a target sequence of interest, and modifying the expression of a sequence of interest. Compositions comprise RNA-guided nuclease polypeptides, CRISPR RNAs, trans-activating CRISPR RNAs, guide RNAs, and nucleic acid molecules encoding the same. Vectors and host cells comprising the nucleic acid molecules are also provided. Further provided are CRISPR systems for binding a target sequence of interest, wherein the CRISPR system comprises an RNA-guided nuclease polypeptide and one or more guide RNAs. Methods and kits for detecting a target DNA sequence are also provided.
Patent MX-2022003977-A (MX)
Title: Cable lockout device.
Inventor: ENGER ANDREW N
IPC: E05B73/00
Filed: 2022-03-31
Abstract: A cable lockout device includes a housing receiving a cable in which the cable forms a loop external to the housing. The housing has a passageway extending therethrough through which the cable extends and has a cable gripping location positioned along the passageway. The cable lockout device further includes a locking arm rotationally coupled to the housing that actuates a cleat or cam spaced from the axis of the locking arm, which cleat or cam can be brought towards another cleat or cam in the cable gripping location (upon closure) or away from the other cleat or cam (upon opening). In a closed position of the locking arm, the locking arm is lockable relative to the body to prevent movement of the locking arm back to the opened position without first unlocking the locking arm relative to the body.
Patent MX-2022006573-A (MX)
Title: Methods of treating inflammatory diseases.
Inventor: GALLER ANNETTE BETTINA
IPC: C07K16/24
Filed: 2017-08-03
Abstract: This invention generally relates to methods for the treatment of IL-23 related diseases, in particular inflammatory diseases, such as psoriasis, psoriatic arthritis or axial (spinal) spondyloarthritis (ax-SpA), including ankylosing spondylitis and non-radiographic ax-SpA, utilizing anti-IL-23A antibodies.
Patent MX-2022007017-A (MX)
Title: Oral product.
Inventor: GERARDI ANTHONY RICHARD
IPC: A24B13/00
Filed: 2020-12-02
Abstract: The disclosure provides products configured for oral use and a process for preparing such oral products. The products include a cannabinoid, a filler, and water. The water content of the oral product is at least about 10% by weight of the oral product, and the water activity of the oral product is no greater than about 0.85.
Patent MX-2022010898-A (MX)
Title: Vascular and aortic connectors with telescoping sheath and deployment methods thereof.
Inventor: PALERMO THOMAS J
IPC: A61F2/90
Filed: 2021-03-04
Abstract: A vascular connector deployment tool may include a handle, an elongated mandrel extending distally from the handle, a vascular connector disposed coaxially about the mandrel, a retractable sheath assembly including an outer sheath telescopically deployed over an inner sheath and an actuator on the handle that is configured to selectively retract the outer sheath and the inner sheath relative to the mandrel. The sheath assembly is configured to constrain the vascular connector against the mandrel in an insertion profile. A distal transition between the outer sheath and the inner sheath visually indicates position of the vascular connector.
Patent MX-NL04000105-A (MX)
Title: Diphenyl azabutane derivative nitroxides as mediators of controlled radical polymerization.
Inventor: GUERRA ENRIQUE SALDIVAR
IPC: C08K5/00
Filed: 2004-12-16
Abstract: The present invention pertains to the field of stable free radicals such as nitroxide, and their use as controllers in living, quasi-living or controlled radical polymerization. The finding that nitroxide structures are effective as controllers, as well as their synthesis and the best conditions of use as polymerization controllers is not trivial. The present invention provides a family of diphenyl azabutane derivative nitroxides having the following general formula: X= Cl, O-CH3, H or other substituents. The invention also provides a method for the chemical synthesis of nitroxides which consists in the oxidation of phenyl or substituted or unsubstituted phenyl-tert-butyl-hydroxylamines by means of air using Cu+2 as a catalyst. The required hydroxylamines are obtained by a nucleophilic addition of magnesium phenyl bromide to tert-butyl-benzylidene-amine oxides. Said nitrones are prepared by the oxidation of the corresponding amines, which are simultaneously synthesized by a reductive amination process of benzaldehydes substituted or unsubstituted with t-butyl amine and sodium borohydride. The aforementioned azabutane-type nitroxides are excellent controllers of the vinyl monomer polymerization, allowing quasi-living polymers with low polydispersities to be obtained. Although the methods of controlled polymerization are known by those who are familiar with the topic, the present invention provides the best molar ratios of azabutane:initiator for obtaining controlled polimerizations.
Patent MX-PA00003538-A (MX)
Inventor: HILLEBRAND STEFAN
IPC: A01N43/653
Filed: 2000-04-11
Abstract: Novel oxiranyl-triazolinethiones of the formulain whichR1, R2 and R3 are each as defined in the description,a process for preparing the novel substances and their use as microbicides in crop protection and in the protection of materials.