baber/WOPTO huggingface dataset:
Patent CA-1340817-C (CA)
Title: Recombinant flagellin vaccines
Inventor: NEWTON SALETE MARIA CARDOZO
IPC: G01N33/569
Filed: 1989-05-05
Granted: 1999-11-09
Abstract: The present invention is directed to recombinant genes and their encoded proteins which are recombinant flagellin fusion proteins. Such fusion proteins comprise amino acid sequences specifying an epitope encoded by a flagellin structural gene and an epitope of a heterologous organism which is immunogenic upon introduction of the fusion protein into a vertebrate host. The recombinant genes and proteins of the present invention can be used in vaccine formulations, to provide protection against infection by the heterologous organism, or to provide protection against conditions or disorders caused by an antigen of the organism. In a specific embodiment, attenuated invasive bacteria expressing the recombinant flagellin genes of the invention can be used in live vaccine formulations. The invention is illustrated by way of examples in which epitopes of malaria circumsporozoite antigens, the B subunit of Cholera toxin, surface and presurface antigens of Hepatitis B, VP7 polypeptide or rotavirus, envelope glycoprotein of HIV, and M protein of Streptococcus, are expressed in recombinant flagellin fusion proteins which assemble into functional flagella, and which provoke an immune response directed against the heterologous epitope, in a vertebrate host.
Patent CA-1318500-C (CA)
Title: External system for locating the geometric center of an internal lens element
Inventor: LOPATA DONALD J
IPC: H01J29/89
Filed: 1989-05-19
Granted: 1993-06-01
Abstract: Abstract of the Disclosure A system  is disclosed  for  externally locating  the geometric center of an internal lens element which requires that an external reference surface be accurately formed so as  to  lie concentrically with  the central  axis of  the internal  lens  element.   This  is  a  accomplished  in  a pressing operation by precisely aligning and securing a ring element to a plunger member.  Three points are then selected on the outer reference surface which are not only utilized  for  positioning the  internal lens  element  for grinding an outer surface to a desired thickness, but also are utilized for aligning and affixing an external lens system in geometric alignment with the internal lens.
Patent CA-1314270-C (CA)
Title: Filling system
Inventor: SU PHILIP P
IPC: B65B9/10
Filed: 1989-05-23
Granted: 1993-03-09
Abstract: ABSTRACT OF THE DISCLOSURE            An  improved  filling  system  for  containers  of  mixtures  of liquid and solid material where the liquid/solid ratio is critical is disclosed.   A prior art problem was that sticky solid material would adhere to the receptacle or bucket in which it was delivered to a filling chute or funnel and it would also stick to the funnel.   This problem is solved by putting the  sticky solid in the buckets and by using the liquid to flush the funnel and by using an air jet to remove any remaining particles from the buckets which are upturned over the funnel.   Alternately, a part of the liquid may be placed in the delivery bucket and when it is tilted or turned upside down to fill the container the remaining part of the liquid is used to rinse the receptacle.  The filling system is especially useful for soups containing noodles or other pasta products.   1/890210.3/SPECFLDR
Patent CA-1310662-C (CA)
Inventor: DEWEERDT HELENE
IPC: C07C67/36
Filed: 1989-06-12
Granted: 1992-11-24
Abstract: Process for the preparation of diesters of hexene-1,6-dioic acid. 
<??>More specifically, a process for the preparation of diesters of 3-hexene-1,6-dioic acid by reaction of carbon monoxide and of an alcohol with at least one butene disubstituted by acyloxy groups in the presence of a palladium-based catalyst, characterised in that the reaction is also conducted in the presence of a quaternary onium halide of an element of group VB chosen from nitrogen and phosphorus, the said element being tetracoordinated with carbon atoms, it being possible for the nitrogen to be coordinated with two pentavalent phosphorus atoms, the halide anion being chosen from chloride and bromide.
Patent CA-1339731-C (CA)
Title: Multiplex genomic dna amplification for deletion detection
Inventor: CASKEY CHARLES T
IPC: C12Q1/6883
Filed: 1989-09-25
Granted: 1998-03-17
Abstract: The present invention relates to a method for detecting multiple DNA sequences simultaneously.  The method involves amplification of multiple sequences simultaneously by annealing a plurality of paired oligonucleotide primers to single stranded DNA.  One member of each pair is complementary to the sense strand of a sequences and the other member is complementary to a different segment of the anti-sense strand of the same sequence.  The amplification occurs by alternately annealing and extending the primers.  The invention also includes oligonucleotide primer sequences helpful in detecting genetic diseases and/or exogenous DNA sequences.
Patent DK-164085-C (DK)
Inventor: SLEYTR UWE B
IPC: B01D15/08
Filed: 1985-11-08
Granted: 1992-10-12
Abstract: PCT No. PCT/EP85/00089 Sec. 371 Date Oct. 28, 1985 Sec. 102(e) Date Oct. 28, 1985 PCT Filed Mar. 8, 1985 PCT Pub. No. WO85/04111 PCT Pub. Date Sep. 26, 1985.A structure usable as an ultrafiltration membrane has membranes (20) with continuous pores which are linked to or into an appropriately porous carrier (21). Each of these membranes (20) consist of protein molecules or protein containing molecules arranged according to a two-dimensional crystal lattice, between which continuous pores of equal size and form remain free, and they are advantageously formed from molecules, which were particularly separated from cell-membranes of procaryons, by means of a recrystallization process designated as self-organization, and which are preferably deposited on or into the carrier (21) and are cross-linked with the carrier (21) intra- or intermolecularly, respectively, through foreign molecules. The structure is suitable, furthermore, for use as a separating organ for a gas separation or for an ion exchange process, as well as for use as a carrier structure for other semi-permeable membranes, such as hyperfiltration membranes. Moreover, with membranes in vesicle form it can serve as a chromatography column and, in the form of film, as envelope material for the most varied substances.
Patent DK-153664-C (DK)
Inventor: BUECHELER HERBERT
IPC: B65D47/42
Filed: 1982-11-22
Granted: 1988-12-27
Abstract: 1. Sponge applicator head (1) for placing on a bottle for a surface treatment medium, such as shoe dye, particularly shoe whitener, wherein the open-pored sponge (2) is partially enclosed as well as compressed by an insert (3) to be plugged into the bottle neck and protrudes from the insert (3) on the outside in the shape of a mushroom or calotte, characterised thereby, that the insert (3) - underneath the uncompressed as well as radially projecting sponge rim (8) - possesses an about axially extending annular groove (10) with holes (11) passing through the insert (3) to the interior of the bottle.
Patent FI-66586-C (FI)
Inventor: LEONARD JACKSON D
IPC: C07C27/02
Filed: 1979-05-24
Granted: 1984-11-12
Abstract: The invention provides a process for the preparation of formic acid by hydrolyzing methyl formate with water at high temperature and pressure in the presence of a formic acid catalyst. Methanol is also formed. The reesterification of the reaction products to methyl formate (a reaction favored by high temperatures) is minimized by flashing the reaction product at relatively low pressure and temperature and thereafter distilling the residual liquid. Thus procedure separates the methyl alcohol from the formic acid with a minimum contact time and at a low temperature which does not favor the reesterification reaction. High purity formic acid may be obtained by subjecting the bottom from the vacuum distillation of further distillation. 
<??>In a preferred embodiment of the invention, prior to the main hydrolysis, the methyl formate is partially hydrolyzed to form the small amount of formic acid needed to accelerate the main hydrolysis step. Accordingly, the necessary formic acid catalyst is formed in situ, thus eliminating the need to add formic acid or to recycle product formic acid.
Patent FI-70350-C (FI)
Inventor: GUEHNE WIELAND
IPC: H04M1/15
Filed: 1982-01-25
Granted: 1986-09-15
Abstract: 1. A device for the storage of electric cables, in particular on vacuum cleaners, having a rotary drive (16, 17, 18, 19, 20, 21, 22, 23) for pushing in the electric cable (13) and laying it in individual loops arranged on top of one another in a storage chamber (7), this rotary drive being coupled to rolls (10, 11) which are arranged at the entrey side of the storage chamber and which have grooves (12) for frictionally gripping the electric cable, characterized in that there are merely two rolls (10, 11) which grip the electric cable (13) and which are supported between the sidewalls (2, 6) of the free storage space shaped in the form of a shaft and are seated in the central region of the mouth (7') of the shaft, and the length (A) of the shaft (7) amounts to a multiple of the width (B) of the shaft.
Patent FI-74579-C (FI)
Inventor: WIESER FRANZ
IPC: A01C1/06
Filed: 1982-11-22
Granted: 1988-03-10
Abstract: A binder solution for applying plant protectants and similar agents to seeds includes a metal pigment such as copper, aluminium or bronze. Presence of the pigment produces a particularly smooth-surfaced coating providing improved abrasion resistance and flow properties.
Patent FI-76539-C (FI)
Inventor: LOEFBERG GUSTAF GERHARD
IPC: B65D88/16
Filed: 1983-04-11
Granted: 1988-11-10
Abstract: A sack-like container, particularly intended for pourable goods, comprises a hose-like casing (10) of flexible material and a rope (15) which has one end thereof joined to a first end-part of the casing, said first end-part being gathered to form a bottom (12) of the container, and extends from the bottom through the container space (14) and slideable out through a second end-part (17) of the casing, said second end-part being gathered to form an upper part (11) of the container. The other end of the rope (15) is bound around the second end-part of the casing and a portion of the rope surrounded by the second end-part. Between the binding location and the location (16) at which the rope exits from the second end-part (17) of the casing, the rope forms a U-shaped lifting loop (19), intended for receiving a lifting hook or like device for lifting the container together with its contents. The aforementioned other end of the rope (15) forms a self-tightening knot (18) so arranged as to permanently lock the aforesaid rope portion against sliding relative to the surrounding end-part (17) of the casing when the lifting loop (19), with the container filled with the intended load and suspended from the loop, is subjected to a load which substantially exceeds, preferably by 1 - 2.5 times, the load exerted on the lifting loop (19) by the suspended, filled container in a static condition.
Patent FI-75410-C (FI)
Inventor: WIRZ PETER
IPC: F16K1/12
Filed: 1984-04-19
Granted: 1988-06-09
Abstract: 1. An instrument which can be built into a fluid conducting pipeline, consisting of a housing (1, 15, 31, 110) of larger diameter than the pipeline and measuring, throttling or shutting-off members accommodated in the housing, characterised by the combination of the following features : a) the housing (1, 15, 31, 110) is formed in one-piece and without welding by an external non-cutting production process with cylindrical end portions (1', 15', 35, 124) matching the pipeline diameter, intermediate sections (1", 15", 34, 123) extending from these end portions and widening conically, and a centre section (1"', 15"', 30, 111) of larger diameter than the pipeline connecting the intermediate sections, b) a support (5, 14, 36, 112) fixed between the inner conical surfaces of the intermediate sections is associated with the measuring, throttling or shutting-off member.
Patent FI-79105-C (FI)
Inventor: ALKER DAVID
IPC: C07D473/10
Filed: 1984-07-19
Granted: 1989-11-10
Abstract: 1,4-Dihydropyridine derivatives of the formula:wherein R is aryl or heteroaryl; R<sup>1</sup> and R are each independently C<sub>1</sub>-C<sub>4</sub> alkyl or 2-methoxyethyl; X is a 5 or 6 membered nitrogen-containing heterocyclic ring which is substituted with one or more hydroxyl or oxo groups and which may optionally be fused to a further 5 or 6 membered nitrogen-containing heterocyclic ring, and which may optionally be further substituted in the heterocyclic ring or further fused heterocyclic ring; Y is -(CH<sub>2</sub>)<sub>n</sub>-, -CH<sub>2</sub>CH(CH<sub>3</sub>)- or-CH<sub>2</sub>C(CH<sub>3</sub>)<sub>2</sub>-; and n is 1 to 3 when X is linked to Y by a ring carbon atom, or 2 or 3 when X is linked to Y by a ring nitrogen atom; and their pharmaceutically acceptable salts, and pharmaceutical preparation containing such compounds, have utility as anti-ischaemic and antihypertensive agents.
Patent FI-89591-C (FI)
Inventor: CANONGE MICHEL
IPC: C07C67/03
Filed: 1988-02-23
Granted: 1993-10-25
Abstract: The invention relates to a process for the continuous preparation of acetates by a transesterification reaction in the homogeneous liquid phase in the presence of a catalyst selected from metallic alcoholates. The process comprises more particularly the introduction of the catalyst into a reactor (R) and the introduction of the reagents, formed by an acetate (I) and an alcohol (II), into a distillation column (D1) surmounting the reactor (R) and operating at a pressure (P1) identical with that in (R). The acetate (III) formed is withdrawn from (R) mixed with the catalyst, which is separated and recycled in (R). An azeotropic mixture (M1), comprising the acetate (I) and the alcohol (IV) formed, emergences at the head of (D1) and feeds a distillation column (D2) at a pressure (P2) lower than (P1), so as to produce at the head of the column an azeotropic mixture (M2) depleted in alcohol (IV), the mixture being recycled in (D1). The process permits the use of relatively humid reagents and alcohols of low reactivity, more particularly secondary alcohols.
Patent NO-161730-C (NO)
Inventor: BERKEY GEORG EDWARD
IPC: C03B37/018
Filed: 1984-09-25
Abstract: This invention relates to a method forming fluorine-doped glass. A coating of glass particles is deposited on the surface of a cylindrical rod of high purity glass. The coated rod is inserted into a furnace which contains a cylindrical muffle formed of high silica content glass. A fluorine-containing atmosphere is flowed through the muffle and over the outer surface of the coating of glass particles and also flows inwardly through the interstices thereof. The temperature within the furnace is sufficiently high to cause fluorine to diffuse into the surfaces of the glass particles and to cause the particles to fuse and form a fluorine-containing dense glass coating on the surface of the rod.
Patent NO-175677-C (NO)
Inventor: KENNEDY CHRISTOPHER R
IPC: C04B35/65
Filed: 1987-09-11
Abstract: A method is disclosed for producing a ceramic body by oxidation of a parent metal, the ceramic body having a graded microstructure characterized by a plurality of zones differing from each other in one or more properties. The zones in the ceramic body are attained by altering the process conditions during formation of said ceramic body such that a zone of the oxidation reaction product formed posterior to said altering has one or more properties different from a zone of the oxidation reaction product formed anterior to said altering.
Patent NO-175427-C (NO)
Inventor: BLAIN DAVID ALAN
IPC: C10N40/25
Filed: 1990-08-15
Abstract: Reaction products in which polyethers are grown from substituted phenol-containing Mannich bases have been found to be effective ashless dispersants and detergents for fuels and lubricants. The reaction products of the invention are obtained by (1) reacting phenol or a C1 to about a C40 alkylphenol with a suitable primary or secondary amine and a C1 to about a C30 aldehyde, thereafter (2) reacting the resultant intermediate product of (1) with an alkali metal or alkali metal salt thereof, and then (3) reacting the product of (2) with a C2 to about a C8 alkylene epoxide or mixtures thereof to produce a polyether-substituted Mannich base.
Patent AU-738299-C (AU)
Title: Drive source for feeding extinguishing medium into spray head for extinguishing fire
Inventor: SUNDHOLM GORAN
IPC: A62C35/00
Filed: 1999-02-01
Granted: 2002-04-11
Abstract: PCT No. PCT/FI99/00068 Sec. 371 Date Sep. 16, 1999 Sec. 102(e) Date Sep. 16, 1999 PCT Filed Feb. 1, 1999 PCT Pub. No. WO99/38573 PCT Pub. Date Aug. 5, 1999A drive source for feeding extinguishing medium into at least one spray head (2, 3) for extinguishing fire has a liquid source (5) and a gas source (9), apparatus for mixing the liquid and gas from their sources (5,9) and apparatus for transporting the mixed liquid and gas to the spray head (2, 3). In order for the drive source to control dosage of the gas into the liquid and, preferably, substantially even and small droplet size for a substantially long time during the extinguishing, the apparatus for mixing the liquid and gas has a piston-and-cylinder apparatus (50) including a first piston (12) in a first cylinder (10) and a second piston (13) in a second cylinder (11) for providing simultaneously at each stroke both liquid and gas to the apparatus or transporting the mixed liquid and gas.
Patent AU-642705-C (AU)
Title: Genetic assay for cytochrome P450
Inventor: WOLF CHARLES ROLAND
IPC: C12Q1/6876
Filed: 1991-01-17
Granted: 2001-07-19
Abstract: Polymorphisms at positions 100, 271, 281, 294, 408, 506 or 1432 of the cytochrome P450 enzyme bufuralol-1'-hydroxylase are indicative of the extensive metaboliser/poor metaboliser phenotypes and can be detected using known methods such as amplification of the DNA with the polymerase chain reaction, followed by digestion with a suitable restriction enzyme and analysis by gel electrophoresis. The EM/PM phenotype is relevant to calculating safe or effective drug doses for individuals.
Patent CA-2000563-C (CA)
Inventor: HARRIS JEFFERY REED
IPC: C09B69/00
Filed: 1989-10-12
Granted: 1995-08-08
Abstract: A two component tint composition is provided which comprises as a first component, a colorant of the formula:       wherein X is a polar group selected from sulfonic acids, sulfonic acid salts, sulfonamides, sulfonates, carboxylic acids, carboxylic acid salts, carboxylic acid amides, carboxylic aldehydes, carboxylic acid esters, ureas, thioureas, nitro groups, hydroxy groups, polyethers, and hydroxyalkylethers; R1 is selected from nitrogen, oxygen, sulfur, or a sulfur, or a sulfur-containing divalent linking group; R2 is hydrogen or a lower alkyl group; a is an integer of from 2-10; b is an integer of from 2-10; c and d are each independently selected from one or two; A is a chromophore selected from nitro, nitroso, monazo, diazo, diarylmethane, triarylmethane, acridine, methine, thiazole, indamine, oxazine, or anthraquinone; and B is -H, -alkyl, or -alkyl carboxylate; and as a second component a diluent selected from alkoxylated fatty acids and long chain alcohols, the weight ratio of diluent to colorant being from about 2.5 to about 5 parts diluent to 1 part colorant.
Patent CA-2013074-C (CA)
Title: Electro-optical ifs finder
Inventor: SHIH I-FU
IPC: G06E1/00
Filed: 1990-03-26
Granted: 1994-07-26
Abstract: ELECTRO-OPTICAL IFS FINDER              ABSTRACT OF THE DISCLOSURE An  electro-optical  system  that  implements  the self-tiling process of finding proper Iterated Function systems  for modeling  natural  objects.   The  system  can operate in two different modes, a real-time interactive mode and an automated mode.  The purpose of the system is to speed up the process of finding a proper IFS for a given object  to be modeled.   The  system makes  use  of optical processing, including optical means for rotating, magnifying/demagnifying and translating an input  image. Optical  beamsplitters  are  used  to  combine  transformed images to produce a tiled output image.  In one embodi-ment,  an automated controller evaluates the goodness of the match between the tiled image and the input image and generates control signals which cause adjustment of the settings of the optical means.  The process is repeated automatically until the match is sufficiently good.  The invention can also be operated in a manual, man-in-the-loop mode.
Patent CA-2014713-C (CA)
Title: Quilting machine with stationary clothholder frame and sewing heads movable in orthogonal directions
Inventor: RESTA MARIO
IPC: D05B11/00
Filed: 1990-04-17
Granted: 2001-10-02
Abstract: The quilting machine comprises a supporting frame with vertical uprights which support, at the top, two horizontal parallel guides. A truck which bears the sewing devices is slidably suspended on the guides. The truck is composed of two side plates connected to one another by two beams which extend above and respectively below the plane of the cloth-holder frame and act as guide for the sewing head of the sewing devices and for the "crochet" device.
Patent CA-2020867-C (CA)
Title: Hydraulic retarder and control
Inventor: KLEMEN DONALD
IPC: F16D57/02
Filed: 1990-07-11
Granted: 1994-10-18
Abstract: HYDRAULIC RETARDER AND CONTROL            Abstract of the Disclosure A hydraulic retarder and control composed of an accumulator, for rapid filling of the retarder; a pulse valve, for controlling fluid flow to and from the accumulator; a regulator valve, for limiting the inlet pressure to the retarder; and a pair of check valves, for preventing fluid flow from the retarder to a pressure source and from the retarder to the accumulator.  The pulse valve is controllable to provide rapid filling of the retarder, while the regulator valve will direct fluid from a secondary source to the retarder and control the pressure at the retarder inlet.  The accumulator is filled from the main pressure source, between retard requests, at a rate that does not disturb the main transmission pressure level.  One of the check valves and the pulse valve prevent the fluid in the accumulator from returning to the system other than when a retard request is present.
Patent CA-2023973-C (CA)
Title: Two and one-half dimensional radar system
Inventor: WARD HAROLD R
IPC: G01S13/42
Filed: 1990-08-24
Granted: 1994-07-05
Abstract: Abstract of the Disclosure A radar system for determining not only the azimuth and range of a target but also the target height over a predeter-mined range of elevation angles has separate receiving and signal processing channels coupled to a dual beam antenna for processing signals returned from a single target.  The output of each signal processor is coupled to a height processor which divides the sum of the received signals into the differ-ence of the two signals.  The resulting ratio is used to access a look-up table to identify the elevation angle associated with the ratio from which the height of the target is calculated. The look-up table includes correction values to compensate for the antenna pattern nonlinearity.