Patent SG-11201406903S-A (SG)
Title: Cell culture compositions and methods for polypeptide production
Inventor: MEIER STEVEN J
IPC: C12N5/00
Filed: 2013-04-24
Abstract: (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 31 October 2013 (31.10.2013) WIPOIPCT (10) International Publication Number WO 2013/163294 A1 (51) International Patent Classification: C12N 5/00 (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: (26) Publication Language: PCT/US2013/037992 24 April 2013 (24.04.2013) English English (30) Priority Data: 61/637,778 61/637,780 13/841,864 24 April 2012 (24.04.2012) US 24 April 2012 (24.04.2012) US 15 March 2013 (15.03.2013) US (71) Applicant (for all designated States except AL, AT, BA, BE, BG, CH, CN, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IN, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PI 1 RO, RS, SE, SI, SK, SM, TR): GENENTECH, INC. [US/US]; 1 Dna Way, Ms49, South San Francisco, CA 94080-4990 (US). (71) Applicant (for AL, AT, BA, BE, BG, CH, CN, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IN, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK SM, TR only): F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124, CH-4070 Basel (CH). (72) Inventors: MEIER, Steven, J.; 1 Dna Way, Ms49, South San Francisco, CA 94080-4990 (US). MUN, Melissa, S.; 1 Dna Way, Ms49, South San Francisco, CA 94080-4990 (US). VIJAYASANKARAN, Natarajan; 1 Dna Way, Ms49, South San Francisco, CA 94080-4990 (US). VARMA, Sharat; 1 Dna Way, Ms49, South San Fran­ cisco, CA 94080-4990 (US). YANG, Yi; 1 Dna Way, Ms49, South San Francisco, CA 94080-4990 (US). ZHANG, Boyan; 1 Dna Way, Ms49, South San Francisco, CA 94080-4990 (US). AREVALO, Silvana, R.; 1 Dna Way, Ms49, South San Francisco, CA 94080-4990 (US). GAWLITZEK, Martin; 1 Dna Way, Ms49, South San Francisco, CA 94080-4990 (US). CARVALHAL, Veron­ ica; 1 Dna Way, Ms49, South San Francisco, CA 94080- 4990 (US). (74) Agents: POLIZZI, Catherine, M. et al.; Morrison & Fo- erster LLP, 755 Page Mill Road, Palo Alto, CA 94304- 1018 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) •rt 0\ CJ m i-H o CJ (54) Title: CELL CULTURE COMPOSITIONS AND METHODS FOR POLYPEPTIDE PRODUCTION (57) Abstract: Cell culture media, such as chemically defined cell culture media, are provided, as are methods of using the media for cell growth (i.e., cell culture) and polypeptide (e.g., antibody) production. Compositions comprising polypeptides produced by the methods are also provided.