baber/WOPTO huggingface dataset:
Patent DE-69633228-D1 (DE)
Inventor: FOSTER ALAN
IPC: A61K47/48
Filed: 1996-04-16
Granted: 2004-09-30
Abstract: A novel agent for the targeted control of a mammalian cell activity can be used to control the interaction of particular cell types with their external environment. The agent has applications as a pharmaceutical for the treatment of a variety of disorders. An agent according to the invention comprises three Domains B, T and E, linked together in the following manner: Domain B-Domain T-Domain E where Domain B is the Binding Domain, which binds the agent to a Binding Site on the cell which undergoes endocytosis to produce an endosome; Domain T is the Translocation Domain, which translocates the agent from within the endosome across the endosomal membrane into the cytosol of the cell; and Domain E is the Effector Domain, which inhibits the ability of the Recyclable Membrane Vesicles to transport the Integral Membrane Proteins to the surface of the cell.
Patent DE-69715407-D1 (DE)
Inventor: WALLACE GEORGE
IPC: A61K33/04
Filed: 1997-04-25
Granted: 2002-10-17
Abstract: Disclosed are methods for sterilizing a female mammal wherein a composition comprising a biocompatible polymer and a biocompatible solvent is delivered to the fallopian tube of the female mammal.
Patent DE-69726020-D1 (DE)
Inventor: WYLIE P
IPC: H04W64/00
Filed: 1997-09-29
Granted: 2003-12-11
Abstract: The present invention relates to a method and system for mobile location estimation in which range measurements between the mobile station and a base station are discriminated as being either from a base station which is line of sight with the mobile station or a base station that is non-line of sight with the mobile station (22). Non-line of sight error present in range measurements from base stations that are non-line of sight with the mobile station is corrected (24). A reconstructed line of sight range measurement is established from the correction of the non-line of sight error. The reconstructed line of sight range measurements can be used with range measurements of base stations determined to be line of sight for accurately locating the mobile station (26).
Patent DE-69729539-D1 (DE)
Inventor: JANSEN RENE
IPC: E04C2/04
Filed: 1997-12-11
Granted: 2004-07-22
Abstract: Corner construction of cardboard-covered plaster board, whereby this board (13) consists of a core (14) and a covering layer (17) provided at least at one side (15) thereof, and whereby the board (13), with the exception of the covering layer (17), is interrupted at the height of the corner and is bent at the height of the covering layer (17) such that two board parts (19-20) are created which form an angle, characterized in that a profile (21) is provided between the board parts (19-20) which is impact-resistant, or at least offer a certain resistance against impacts, and which fits, respectively is situated against the covering layer (17), at the location where this latter is bent. <IMAGE>
Patent DE-69731951-D1 (DE)
Inventor: PIESSENS PAUL
IPC: B09B1/00
Filed: 1997-09-17
Granted: 2005-01-20
Abstract: Extracting gases produced by fermentable substances and collecting the gases in a reservoir, using a relative pressure function to regulate the process, obtained from a metrological forecast, especially of barometric pressure, and lowering the pressure when a reduction in atmospheric pressure is forecast, is new. Extracting gases produced by fermentable substances and collecting the gases in a reservoir, using a relative pressure function to regulate the process, obtained from a metrological forecast, especially of barometric pressure, and lowering the pressure when a reduction in atmospheric pressure is forecast, is new. The gas produced by the procedure is consumed in a burner, with admitted air measured at the burner and the flow of extracted gas regulated accordingly. The extracted gas flow is also regulated according to the content of volatile organic compounds measured in the peripheral zone. An Independent claim is also included for the apparatus used for the method, comprising: (a) gas extraction reservoir; (b) a pressure gauge (17) incorporating a barometric pressure forecaster; (c) an extracted gas regulator (19) with a control valve; and (d) a burner (18) linked to the extracted gas reservoir to consume the gas, equipped with an ignition safety unit.
Patent DE-69738873-D1 (DE)
Inventor: YOU LI
IPC: C12N15/55
Filed: 1997-10-31
Granted: 2008-09-11
Abstract: New mutant penicillin G acylases preferably from E. coli are provided, exhibiting altered enzymatic activity. These penicillin G acylases are obtained by expression of a gene encoding said penicillin G acylase having an amino acid sequence which differs at least in one amino acid from the wild-type penicillin G acylase.
Patent DE-69740096-D1 (DE)
Inventor: YOUNG ANDREW A
IPC: C07K5/00
Filed: 1997-08-08
Granted: 2011-02-17
Abstract: A pharmaceutical composition comprising an exendin-4 peptide comprising the amino acid sequence HGEGTFTSDL SKQMEEEAVR LFIEWLKNGG PSSGAPPPS in an amount from 0.001 mg to 1 mg based on a 70 kg patient; a pharmaceutically acceptable buffer; a pharmaceutically acceptable isotonicity agent; and a pharmaceutically acceptable carrier.
Patent DE-69804597-D1 (DE)
Inventor: STOICA FELICIAN TITUS
IPC: A61K36/15
Filed: 1998-02-25
Granted: 2002-05-08
Abstract: The invention refers to an ointment used for the treatment of skin diseases and especially of superficial and profound burns. The ointment is very efficient for the rapid and successful treatment of burns of IIIrd and IVth degree. It is also used for the treatment of shank ulcer and of cervicitae in gynecology. The ointment composition, expressed in percentage by weight, is of 45...67 % edible sunflower oil, 15...37 % edible olive oil, 1...2 % extract from the plant Calendulae officinalis, 0.8...1.8 % incense, 2.5...8 % colophony, 6.5...11.5 % white beeswax, 0.7...1.8 % subgallic bismuth and 0.7...1.8 % camphor.
Patent DE-69813908-D1 (DE)
Inventor: WALLIMANN THEO
IPC: A61K31/205
Filed: 1998-07-28
Granted: 2003-05-28
Abstract: The method, composition, and use of the composition for healing defects in bone or cartilage tissue in animals and humans caused by trauma or surgery is disclosed. The method includes administration of creatine compounds including analogues or pharmaceutically acceptable salts thereof. Treatment in accordance with the method speeds-up time for and improves the process of healing of defects in bone or cartilage tissue in animals and humans caused by trauma or surgery including acceptance and bonding of artificial implants. The treatment with creatine compounds can be therapeutic for diseased patients, preventive for healthy people, as well as geriatric for elderly people.
Patent DE-69839306-D1 (DE)
Inventor: CAO ZHISONG
IPC: A61K31/4375
Filed: 1998-07-10
Granted: 2008-05-08
Abstract: A method is disclosed for the preparation of 9-nitrocamptothecin which involves reacting 20-camptothecin with at least one inorganic nitrate salt and at least one acid effective in catalyzing the formation of a nitronium ion, where the reaction occurs at a temperature and for a time sufficient to form the 9-nitrocamptothecin. Also, methods of further purifying the 9-nitrocamptothecin by column chromatography or by reprecipatation is also disclosed.
Patent DE-69841317-D1 (DE)
Inventor: JETTE ROGER
IPC: H02G3/04
Filed: 1998-09-11
Granted: 2010-01-07
Abstract: A support apparatus for use with a raised floor system including a plurality of support pedestals and floor panels, includes a support bracket having first and second end portions being configured and dimensioned to rest upon a portion of a support pedestal. An intermediate portion extends between the first and second end portions, and an article support member depends from the intermediate portion to support articles thereon a distance below the raised floor panels and a distance above a base.
Patent DE-69901122-D1 (DE)
Inventor: HARRIS CRAIG PAUL
IPC: B62D25/08
Filed: 1999-07-20
Granted: 2002-05-02
Abstract: A subassembly for a motor vehicle is disclosed in which the energy of impact is directed away from a front bulkhead (50) of a passenger cell. This has the advantage that intrusion into the passenger cell in the event of an impact is reduced. On each side of the passenger cell connecting members (54) are connected between a support structure (60) beneath the passenger cell to a pillar (52) adjacent the front of the cell. A cross member (62) is connected between each of the connecting members. Longitudinal members (70) extend forwardly of the connecting members (54).
Patent DE-69905312-D1 (DE)
Inventor: CONINCK HUBERT
IPC: B29C65/26
Filed: 1999-07-14
Granted: 2003-03-20
Abstract: The mirror has at least two distinct areas which can be moved separately to heat only the portion of the edges to be welded . An Independent claim is included for the corresponding method. Objects are positioned with edges facing. Two parts of the hot mirror are moved separately between the edges, their temperatures being sufficient for contact-melting of the plastic. Pressing edges to the mirror for a sufficient interval, initiates melting, starting from the surfaces in contact. The objects are retracted, the mirror is extracted, and the objects are pressed together for a sufficient time for welding and setting, before extracting the product.
Patent DE-69913339-D1 (DE)
Inventor: WEISS JAMES M
IPC: A61F2/30
Filed: 1999-04-23
Granted: 2004-01-15
Abstract: A hip replacement is performed by separating a femoral head from a femoral neck in a patient's body, fragmenting of the femoral head and removing the fragments from the body, and molding in-situ in the body a neo femoral head joined to the femoral neck. The molding is performed by inserting a molding device, formed of bioabsorbable material, through a hole formed through the femoral head and the femoral neck. The molding device includes an expandable balloon which is expanded by the introduction of molding material, whereby the balloon forms the shape of the neo femoral head.
Patent DE-69916816-D1 (DE)
Inventor: EXNER THOMAS
IPC: C12Q1/56
Filed: 1999-02-01
Granted: 2004-06-03
Abstract: A method of determining the coagulation potential of a plasma sample be pre-incubating the plasma sample with a reagent such that endogenous protein C in the plasma is at least partially converted into activated protein C by the reagent, adding factor Xa which is progressively inactivated by antithrombin III/heparin cofactor 2 during the preincubation, adding an exogenous reagent which activates factor X to Xa or prothrombin to thrombin in a factor V-dependent manner, monitoring a reaction indicative of the rate of coagulation of the plasma sample, comparing that rate of coagulation control, or the equivalent rate determined for an individual without impaired coagulation control, or the equivalent rate determined for the plasma sample in the absence of protein C activator, and determining the coagulation potential of the plasma sample from one or other of the compairsons.
Patent DE-69922519-D1 (DE)
Inventor: GRAHEK ROK
IPC: A61K31/22
Filed: 1999-09-17
Granted: 2005-01-13
Abstract: Lovastatin, pravastatin, simvastatin, mevastatin, atorvastatin, and derivatives and analogs thereof are known as HMG-CoA reductase inhibitors and are used as and antihypercholesterolemic agents. The majority of them are produced by fermentation using microorganisms of different species identified as species belonging to Aspergilus, Monascus, Nocardia, Amycolatopsis, Mucor or Penicilium genus, some are obtained by treating the fermentation products using the method of chemical synthesis or they are the products of total chemical synthesis. The purity of the active ingredient is an important factor for manufacturing the safe and effective pharmaceutical, especially if the pharmaceutical product must be taken on a longer term basis in the treatment or prevention of high plasma cholesterol. The accumulation of the impurities from the pharmaceuticals of lower purity may cause many side effects during the medical treatment. The present invention relates to a new industrial process for the isolation of HMG-CoA reductase inhibitors using so-called displacement chromatography. Use of the invention enables to obtain HMG-CoA reductase inhibitors of high purity, with high yields, lower production costs and suitable ecological balance.
Patent DE-69923640-D1 (DE)
Inventor: CANNET GILLES
IPC: F16K1/30
Filed: 1999-09-22
Granted: 2005-03-17
Abstract: The valve is operated by a lever enclosed by a cover and having a tip which projects from the cover in the valve's open position and is made so that it can bend or break off in the event of an accidental impact. The valve is operated by a lever (8) mainly enclosed by a cover and having a tip (8a) which projects from the cover in the valve's open position and is made so that it can bend or break off in the event of an accidental impact. The tip (8a) is connected to the main body of the lever by a rupture line and/or is located inside a sleeve (6) of an elastically deformable material, preferably in a bright color such as orange.
Patent DE-69932276-D1 (DE)
Inventor: LONKA PEKKA
IPC: H04M1/724
Filed: 1999-03-16
Granted: 2006-08-24
Abstract: A mobile telecommunication device comprises a first part (601) and a second part (602) interconnected by a hinge. Said first part comprises a display (606), a radio transmitter/receiver (604) an internal antenna (603), a loudspeaker (605) and a microphone (611), and said second part comprises an arrangement for fastening a battery (610) to said second part, said second part being configured to be held in a user's hand during operation of the mobile telecommunication device. The mobile telecommunication device further comprises a plurality of keys (608, 609), wherein at least a major part of said plurality of keys is comprised in said second part.
Patent DE-69935987-D1 (DE)
Inventor: CALLINAN GARRY KEVIN
IPC: E02B11/00
Filed: 1999-08-06
Granted: 2007-06-14
Abstract: A foundation comprising one or more layers or mattresses of tires, and a fill material provided within and/or between tires of each of the mattresses. The fill material is preferably a relatively coarse aggregate and provides a porous bed having relatively high drainage capacity. The lowermost mattress is cloth which is designed to allow the passage of water across the lowermost mattress whilst preventing the ingress of relatively finer material into the fill material and which can otherwise lead to degeneration of the foundation. At least some of the tires typically also have an upper sidewall removed therefrom.
Patent DE-502004001650-D1 (DE)
Inventor: OLDIGES RAINER
IPC: A47C23/06
Filed: 2004-08-17
Abstract: The mattress for a bed has a lath frame along its longitudinal edges and at least two mattress cushions (2) with individual lath frames. The individual lath frames are directly or indirectly attached to the cushions. The mattress pads can be made of natural fibres or natural rubber or a combination of them.
Patent DE-502004002857-D1 (DE)
Inventor: LEGER JOACHIM DR-ING
IPC: D01G25/00
Filed: 2004-07-01
Abstract: A fleece laying apparatus comprises a camel back cross lapper having an infeed zone, an output conveyor, a supply arm, a layering arm with a lower end reciprocatingly guided on a path above the output conveyor, and two delivery transport belts; and variable-volume web buffering apparatus upstream of the infeed zone and adapted to hold a web between two take-up transport belts. A fleece laying apparatus comprises a camel back cross lapper having an infeed zone, an output conveyor, a supply arm, a layering arm with a lower end reciprocatingly guided on a path above the output conveyor, and transverse to an output direction of the output conveyor, and two delivery transport belts guided in juxtaposed fashion from the infeed zone to the layering-arm lower end; and variable-volume web buffering apparatus upstream of the infeed zone and adapted to hold a web between two take-up transport belts, at least one of which is one of the two delivery transport belts, the web buffering apparatus including a movable common frame, and frame rollers rotatably mounted on the common frame, the frame rollers including a two-belt roller deflecting the take-up transport belts by 180% and >=2 one-belt rollers, the common frame movable transverse the roller axes, at least one of the one-belt rollers wrapped by the one delivery transport belt, such belt guided through an upstream web take-up site to the infeed zone, where web is sandwiched between paired belts for the entire path from the take-up site to the output conveyor.
Patent DE-502004007690-D1 (DE)
Inventor: STEINMANN MATTHIAS
IPC: H04H60/31
Filed: 2004-09-02
Abstract: The method involves transmitting an electromagnetic identification signal with a defined range from each article (1a-1c) whose instantaneous data content is received by a personal device (7a-7d) carried by a person (6a-6d) within range and storing the data content in a memory in the personal device. The transmission range and the reception sensitivity of the device are matched so that no data reception is possible if the device is outside a normal human attention or sensitivity range. Independent claims are also included for the following: (a) an arrangement for implementing the inventive method (b) a personal device forming part of the inventive arrangement (c) and a transmission unit forming part of the inventive arrangement.
Patent DE-502004007855-D1 (DE)
Inventor: HOROWSKI REINHARD
IPC: A61K9/70
Filed: 2004-05-30
Abstract: The invention relates to a transdermal therapeutic system containing ergolin compounds, preferably lisuride, in which the ergolin compound is stabilized. The oxidation-sensitive ergolin compound is stabilized by a combination of at least one liposoluble, free radical-scavenging antioxidant, preferably di-tert.-butyl methyl phenol, di-tert.-butyl metoxy phenol, tocopherol or ubiquinone and a basic polymer.
Patent DE-502004009006-D1 (DE)
Inventor: FECHT ALBERT
IPC: B05B1/06
Filed: 2004-11-13
Abstract: The conical nozzle has a nozzle component (10) with a swirl chamber (18), a feed bore (22) in one wall of the swirl chamber, and an outlet bore (20) in a first end wall of the swirl chamber. An axially symmetrical protrusion (30) or recess is provided on a second end wall of the swirl chamber, and at least two blind holes (32) are located in the first end wall adjacent to the outlet bore. An encompassing annular chamber in communication with the feed bore and nozzle component is provided in the region of the feed bore.
Patent DE-502004011834-D1 (DE)
Inventor: KRANEWITTER WOLFGANG
IPC: C12Q1/70
Filed: 2004-12-07
Abstract: Oligonucleotides (ON) that can be used as primers for amplification of nucleic acid regions of genital human papilloma virus (HPV), are new. Oligonucleotides (ON) that can be used as primers for amplification of nucleic acid regions of genital human papilloma virus (HPV) are new. Specifically they have sequence comprising 25 nucleotides (SEQ ID No.:1), especially for use as forward primer, and sequence comprising 23 nucleotides (SEQ ID No.:7), especially for use as reverse primer 5'-CARGC(I or N)AAAWWWKTDAARGAYTGT (SEQ ID No.:1) 5'-ARYGGYTSYARCCAAAARTGRCT (SEQ ID No.:7) where R = A or G; W = T or A; K = T or G; I = inosine; N = A,T,G or C; D = A, T or G; Y = C or T and S = C or G. Independent claims are also included for: (1) oligonucleotide (ON1) useful as probe for detection and/or determination of genital subtypes of HPV having any of 24 sequences reproduced; (2) specified mutant of ON or ON1; (3) oligonucleotides (ON2) having a sequence that is complementary to ON or ON1 over its entire length; (4) primer pair for amplification of a nucleic acid region of a genital HPV comprising at least one ON or ON1, or their specified mutants; (5) nucleic acid (NA1) comprising at least one region of ON1 (or its mutants or complements) plus one or more additional regions of at least one nucleotide (nt); (6) nucleic acid (NA2) that is complementary to NA1 over its entire length; (7) amplifying a region of genital HPV, present in a biological sample, that uses at least one each of forward and reverse primers as defined; (8) detecting/determining a genital HPV genotype by hybridization with ON1, its mutant or complement; (9) array for detecting/determining the genotype of HPV that contains the new oligonucleotides and/or nucleic acids that contain them; and (10) kit for detecting/determining the genotype of a genital HPV containing any of the new primers, primer pairs or probes.
Patent DE-502005003333-D1 (DE)
Inventor: KELLER MARTIN RICHARD
IPC: B65H19/18
Filed: 2005-03-14
Abstract: The invention relates to a device for pressing a material web onto the outer periphery of a supply roll, by means of a pressure organ. The pressure organ comprises at least one support element and elastically deformable brushes, which can be placed against the material web, are fixed to the support element. The pressure organ comprises at least one brush strip.
Patent DE-502005006732-D1 (DE)
Inventor: BUCK ALFRED ERNST
IPC: A61F2/44
Filed: 2005-08-23
Abstract: The implant has a wire and/or a fiber, which are partially presented as flexible pressed knitted fabric. The wire and/or the fiber include biocompatible material such as titanium or high-grade steel, and absorbable material such as inter alia or catgut. The wire and/or the fiber have a diameter approximately 0.01 millimeter to 5 millimeter. The knitted fabric is presented as flexible tube. Independent claims are also included for the following: (A) a method of manufacturing an implant (B) an application of the implant as a part of inter-vertebral disk prosthesis (C) an application of the implant as a part of a joint implant (D) an application of the knitted fabric for manufacturing of an implant.
Patent DE-502006000043-D1 (DE)
Inventor: HEULER MICHAEL
IPC: F16H45/00
Filed: 2006-03-03
Abstract: The hydrodynamic coupling device (1) has a bridging clutch (56) which is enclosed by hydrodynamic ring (24) and is arranged opposite to a pressurized pressure chamber (55) to which a piston (54) is attached through sealing (170) whereby a pressure area connection is arranged at the piston. The piston independently engages and disengages between its relative position. A replacement of clutch fluid between the hydrodynamic ring and pressure chamber is producible independent of the switching condition of the bridging clutch.
Patent DE-502006000753-D1 (DE)
Inventor: MATHAR JOCHEN J
IPC: G05G5/28
Filed: 2006-02-06
Abstract: An operating lever (OL) (2) works on bearings in a ball-and-socket joint (4) that allows swiveling movement in the OL in all directions. Linked to the OL, first (9) and second (10) coupling devices (CD) fit on the OL so that, when the OL swivels in a first level of movement, the first CD swivels and only the second CD twists.
Patent DE-502006004061-D1 (DE)
Inventor: MOHR PETER
IPC: B23B31/26
Filed: 2006-01-21
Abstract: The invention relates to a clamping device for removably mounting a tool (3) or a tool fixture in a receiving part (1). Said clamping device comprises several pincers elements (33) which are concentrically arranged around a central axis (32) within the receiving part (1) and are impinged upon by a tension spring (39) so as to be moved into a clamping position in order to brace the tool (3) or the tool fixture. In order to be able to automatically replace a tool without using much force and energy, an axially movable closing element (17) is assigned to the pincers elements (33). Said closing element (17) impinges the pincers elements (33) in a forward position that is advanced in the direction of the pincers elements (33) for mounting purposes in the clamping position thereof, which is swiveled inward by means of the tension spring (39), while being movable into a retracted position with the aid of a detaching device (12, 16, 45, 46, 47) in order to release the pincers elements (3).