baber/WOPTO huggingface dataset:
Patent BR-PI1014276-B1 (BR)
Title: produção de nanopartículas encapsuladas em escala comercial
Inventor: AARON DODD
IPC: A61K9/14
Filed: 2010-04-23
Abstract: A presente invenção se refere a métodos para produzir partículas de um material biologicamente ativo usando processos de moagem a seco bem como composições compreendendo tais materiais, medicamentos produzidos usando tais materiais biologicamente ativos em forma de particulado e/ou composições, e a métodos de tratamento de um animal, incluindo humano, usando uma quantidade terapeuticamente eficaz de tais materiais biologicamente ativos administrados por meio de tais medicamentos.
Patent EA-008609-B1 (EA)
Title: 2'-fluoronucleosides
Inventor: SCHINAZI RAYMOND F
IPC: A61K31/505
Filed: 1999-02-25
Abstract: 2'-Fluoronucleoside compounds are disclosed which are useful in the treatment of hepatitis B infection, hepatitis C infection, HIV and abnormal cellular proliferation, including tumors and cancer. The compounds have general formulae (I), (II), (III), (IV) wherein Base is a purine or pyrimidine base; Ris OH, H, OR, N, CN, halogen, including F, or CF, lower alkyl, amino, loweralkylamino, di(lower)alkylamino, or alkoxy, and base refers to a purine or pyrimidine base; Ris H, phosphate, including monophosphate, diphosphate, triphosphate, or a stabilized phosphate prodrug; acyl, or other pharmaceutically acceptable leaving group which when administered in vivo, is capable of providing a compound wherein Ris H or phosphate; sulfonate ester including alkyl or arylalkyl sulfonyl including methanesulfonyl, benzyl, wherein the phenyl group is optionally substituted with one or more substituents as described in the definition of aryl given above, a lipid, an amino acid, peptide, or cholesterol; and Ris acyl, alkyl, phosphate, or other pharmaceutically acceptable leaving group which when administered in vivo, is capable of being cleaved to the parent compound, or a pharmaceutically acceptable salt thereof.
Patent EA-005665-B1 (EA)
Title: Method for removing a cable core from a cable sheath
IPC: H02G/
Filed: 2002-02-20
Abstract: The invention relates to a method for removing a cable core from a cable sheath, said cable core comprising a casing (8). A flowing medium (22) is introduced under pressure into the cable duct (9) at one end of the cable to reduce friction and a tension force (F) is exerted on the cable core at one end (5) of the cable (1). According to the invention, a method by which extant cable may have the cable core thereof released as rapidly and economically as possible may be achieved whereby the flowing medium is specifically introduced into the annular space between the inner side of the cable sheath and the casing (8) of the cable core.
Patent EA-007382-B1 (EA)
Title: Substituted benzopyrans as selective estrogen receptor-beta agonists
Inventor: DODGE JEFFREY ALAN
IPC: C07D493/02
Filed: 2002-11-07
Abstract: The present invention relates to substituted benzopyran derivatives, stereoisomers, and pharmaceutical acceptable salts thereof and processes for the preparation of the same. The compounds of the present invention are useful as Estrogen Receptor beta agonists. Such agonists are useful for the treating Estrogen Receptor beta mediated diseases such as prostate cancer.
Patent EA-011117-B1 (EA)
Title: Method of hydromagnetotherapy (variants) and device therefor
Inventor: PLETNEV SERGEY VLADIMIROVICH
IPC: A61H33/00
Filed: 2006-03-28
Abstract: The invention relates to medicine, in particular, to a method and device for performing magnetotherapy and/or prophylaxis human's diseases. The therapy effect is achieved by using simultaneously combined acoustic and vibratory effect in the presence of liquid medium, wherein a harmonic input is used as acoustic influence, creating an effect and medical solutions are used as the liquid medium. An amplitude of magnetic field is modulated by an acoustic signal.
Patent EA-012625-B1 (EA)
Title: Cytotoxic agents comprising new taxanes
Inventor: MILLER MICHAEL L
IPC: A61K39/395
Filed: 2005-12-02
Abstract: The present invention relates to novel cytotoxic agents and their therapeutic use. More specifically, the invention relates to novel cytotoxic agents comprising taxanes and their therapeutic use. These novel cytotoxic agents have therapeutic use as a result of delivering the taxanes to a specific cell population in a targeted fashion by chemically linking the taxane to a cell binding agent.
Patent EA-015911-B1 (EA)
Title: Aqueous active ingredient concentrate having an herbicidal effect
Inventor: BRATZ MATTHIAS
IPC: A01N25/32
Filed: 2007-08-03
Abstract: The invention relates to an aqueous active ingredient concentrate, comprising in dissolved form: a) at least one 4-benzoyl-substituted pyrazol compound of the formula (I)in which substituents values are given in claims; b) at least one benzoic acid compound of the formula (II)in which substituents values are given in claims; c) have at least one non-ionic surface-active substance S, selected from polyether compounds having repeat units, derived from ethylene oxide, alkylpolyglycosides and mixtures thereof, wherein the weight ratio of total amount of active substance of pyrazol compound of formula I and compounds of benzoic acid of formula II to the nonionic surfactant S in the range of from 1:10 to 3:1.
Patent EA-021392-B1 (EA)
Title: Smokeless tobacco product
Inventor: FUISZ RICHARD
IPC: A24F47/00
Filed: 2008-10-02
Abstract: A nonaqueous, extrudable composition including at least one thermoplastic polymer in an amount of more than 20 wt% of the whole composition and tobacco. A smokeless tobacco product in the form of a sheet can be made by extruding or hot melt shaping a nonaqueous composition comprising at least one thermoplastic polymer and tobacco, the sheet being soluble in a user's mouth and resulting in sustained release of nicotine to the user. The sheet for delivery of superbioavailable nicotine to the user can be in a form that may be placed in contact with the mucosa of the user, and have an average dissolution time of 5 to 50 minutes.
Patent EA-020820-B1 (EA)
Title: Electro-optical layered appliance with variable transmittance and method of preparation thereof
Inventor: TIMUSK MARTIN
IPC: G02F1/139
Filed: 2010-03-25
Abstract: The invention relates to a method of preparation of an electro-optical layered appliance with variable transmittance and to an electro-optical layered appliance including such surface coating. The method comprises dispersing of liquid crystal microdroplets in a mixture of an alkoxide and a solvent forming hydrolyzable and polymerizable precursor that is sprayed through an acidic water vapour atmosphere on a substrate coated with an electrically conductive and transparent film. Applying the material to the surface by spraying is intrinsically related to the synthesis processes because the properties of the surrounding environment (i.e. content of water and acidity, UV radiation) and the chemical reactions, such as hydrolysis and polymerization reactions that take place during spraying have considerable influence on the properties of the sprayed layer (i.e. driving voltage, thickness of obtained layer), providing to form a matrix, onto which a dielectric material, a second transparent electrically conductive film and an additional layer, covering all the structure, from the substrate material are further applied. The obtained electro-optical layered appliance has several layered structures between the substrate and the protective layer comprising a first transparent electrode, a matrix layer with dispersed microdroplets of liquid crystal, a dielectric layer and a second transparent electrode. The electrically conductive transparent electrodes obtained by the described method are provided with contacts for applying voltage. The different layers have a common contact, for example ground.
Patent EA-016789-B1 (EA)
Title: Data storage medium
Inventor: JARVIS ANTHONY
IPC: G11B7/246
Filed: 2009-08-26
Abstract: A data storage medium comprising recording information in the form of a track of data points, the colour of each data point being selected from at least three different colours, wherein the recording information is disposed on a substrate which comprises a colour forming composition, wherein said colour forming comprises a colour former which is susceptible to changing to at least three different colours when irradiated with a laser, wherein the colour former is a leuco dye, a diacetylene or a carbazole. Methods of forming the data storage medium and methods of reading the medium are also provided.
Patent EA-021840-B1 (EA)
Title: Use of steroid compounds for inflammatory and autoimmune disorders
Inventor: PANOUTSAKOPOULOU VASILIKI
IPC: A61P43/00
Filed: 2010-09-13
Abstract: This invention pertains to a method of preventing or treating an inflammatory condition, comprising administering to a patient an effective amount of a compound selected from the following: 17β-spiro-[5-androsten-17,2′-oxiran]-3β-ol; (20S)-3β,21-dihydroxy-17β,20-epoxy-5-pregnene; (20S)-3β-hydroxy-17β,20-epoxy-20-(2-bromoethynyl)-5-androstene; 3β,21-dihydroxy-17α,20-epoxy-5-pregnene and pharmaceutically acceptable esters and salts thereof, and also to the use of said compounds for preventing or treating an inflammatory condition.
Patent EA-017488-B1 (EA)
Title: Fixation device
Inventor: SHAROJKO MIKHAIL MIKHAILOVICH
IPC: A45F5/10
Filed: 2011-11-21
Abstract: The invention relates to fixing means of different articles and to carry thereof and also to quick-acting fixing means and can be used in transport facilities, high-altitude mounting activities and fire-rescue operations. The technical inventive result is aimed at improving reliability of articles fixation and widening of technological abilities and characterized in that the fixation device comprises a holder for a hand, a hook, a clamping element in the form of a double-arm hinged connected to the holder and a spring. According to the invention the lever arms are positioned at an angle, free lever ends facing each other, the holder has a guide for one of lever arms, wherein the free lever end of the other is pressed to a hook free end spring actuated adapted to press out in fixing a load. The holder is provided with rubbered lining with cutouts for fingers.
Patent EA-028309-B1 (EA)
Title: Chimeric factor viii polypeptides and uses thereof
Inventor: CHHABRA EKTA SETH
IPC: A61K38/37
Filed: 2013-01-12
Abstract: The present invention provides a VWF fragment comprising the D' domain and D3 domain of VWF, a chimeric protein comprising the VWF fragment and a heterologous moiety, or a chimeric protein comprising the VWF fragment and a FVIII protein and methods of using the same. A polypeptide chain comprising a VWF fragment of the invention binds to or is associated with a polypeptide chain comprising a FVIII protein and the polypeptide chain comprising the VWF fragment can prevent or inhibit binding of endogenous VWF to the FVIII protein. By preventing or inhibiting binding of endogenous VWF to the FVIII, which is a half-life limiting factor for FVIII, the VWF fragment can induce extension of half-life of the FVIII protein. The invention also includes nucleotides, vectors, host cells, methods of using the VWF fragment, or the chimeric proteins.
Patent EA-037463-B1 (EA)
Title: Halobacteria extracts composition for tumor reduction
Inventor: KUCHINA NONA
IPC: A61P35/00
Filed: 2013-09-16
Abstract: The present invention provides a composition and method for treating solid tumors in a mammalian subject by enhancing radiation treatment influence. The composition comprising halobacterial extracts and Dunaliella extracts containing antioxidants comprises: (a) at least one water soluble fraction; and (b) at least one oil soluble fraction, wherein said extracts as a co-composition are adapted for therapeutic treatment for solid tumor reduction. Furthermore, the composition comprising halobacterial extract and Dunaliella extract is adapted to promote solid tumor reduction in radiation treatment in vitro and in vivo.
Patent EA-034825-B1 (EA)
Title: Single high doses of mva induce a protective immune response in neonates and infants
Inventor: CHEMINAY CEDRIC
IPC: A61K39/165
Filed: 2014-03-14
Abstract: The present invention relates to compositions and methods for inducing a protective immune response against a poxvirus in human neonates or infants of less than 6 months of age. The present invention encompasses administering a single high dose of an MVA to a human neonate or infant of less than 6 months of age, wherein the administration induces protective T- and B-cell responses against a poxvirus in the human neonate or infant.
Patent EA-036924-B1 (EA)
Title: Absorbent article
Inventor: MUKAI HIROTOMO
IPC: A61F13/532
Filed: 2017-06-05
Abstract: An absorbent article (1) includes an absorbent main body (10) including an absorbent core (40), and a pair of leak-proof walls (20). The pair of leak-proof walls are provided on respective widthwise side portions of the absorbent main body (10). Each of the leak-proof walls (20) is capable of standing on a skin side in the thickness direction, and includes a skin-side portion (23) and a non-skin-side portion (24). A joined part (27) is formed by joining at least partially a surface of the skin-side portion (23) and a surface of the non-skin-side portion (24), the surfaces facing to each other. The absorbent main body (10) includes a crotch stretchable portion (15) in a central portion in the width direction and the longitudinal direction, and the crotch stretchable portion (15) stretches/contracts in at least one direction of the longitudinal direction and the width direction. The joined part (27) is provided inside a distal end of the leak-proof wall (20) and outside the crotch stretchable portion (15) in the width direction. A part of the joined part and a part of the crotch stretchable portion at least overlap in the longitudinal direction.
Patent ES-2165299-B1 (ES)
Title: Nuevo procedimiento para la obtencion de diosmina a partir de materia prima vegetal.
Inventor: DEL RIO CONESA JOSE ANTONIO
IPC: A61K31/7048
Filed: 2000-01-27
Granted: 2003-05-16
Abstract: Nuevo procedimiento para la obtención de diosmina a partir de materia prima vegetal. Comprende: secar y moler la materia prima vegetal, someterla a un primer proceso de extracción con éter de petróleo obteniéndose un residuo de extracción que se somete a un segundo proceso de extracción con metanol, de cuyo extracto se recupera la diosmina que si se desea se puede someter a cristalización para su purificación. Aplicación en la industria farmacéutica.
Patent ES-2190299-B1 (ES)
Title: Dispositivo motoreductor de enrollamiento de persianas y toldos y metodo de operacion.
Inventor: MARTIN PINA VICENTE
IPC: E06B9/88
Filed: 2000-02-02
Granted: 2004-04-01
Abstract: Dispositivo motoreductor de enrollamiento de persianas y toldos y método de operación. Constituido por un tubo exterior (3) en el interior del cual se fija un motor eléctrico (14) que actúa a través de un electrofreno (13) y un reductor planetario (15) sobre una contera motriz (4) que se acopla giratoriamente al interior de un tambor poligonal (17) al que transmite su movimiento, y sobre el que se produce el enrollado/desenrollado de una persiana o toldo (18), controlándose su posición mediante un potenciómetro lineal (16) unido a una tuerca prisionera (10) que puede desplazarse longitudinalmente en ambos sentidos respecto a una varilla roscada (19) solidaria de una rueda dentada (7) que engrana por el interior de una contera de mando (2) que recibe el movimiento del tambor poligonal (17) a cuyo interior se acopla giratoriamente. Un circuito impreso (11) memoriza las posiciones extremas de subida/bajada de las primeras operaciones realizadas después de haber accionado un microrruptor.
Patent ES-2198171-B1 (ES)
Title: Composicion cosmetica y/o farmaceutica conteniendo metalotioneina.
Inventor: ARMENGOL SEGURA RICARD
IPC: A61Q17/00
Filed: 2000-09-06
Granted: 2005-04-16
Abstract: Composición cosmética y/o farmacéutica conteniendo metalotioneina. Es una composición cosmética y/o farmacéutica conteniendo proteínas metalotioneínas (MT). Es adecuada para la protección externa contra el contacto de metales pesados y/o contra la radiación de la luz UV.
Patent ES-2167269-B1 (ES)
Title: Dispositivo de peso variable para pesca al currican.
Inventor: CAMARASA MONGE ANTONIO
IPC: A01K95/00
Filed: 2000-09-27
Granted: 2003-11-01
Abstract: Dispositivo de peso variable para pesca al currican. Comprende un cuerpo hueco (11) formado por un tubo (2) y dos casquetes (1) dispuestos en sus extremos, estando atravesado centralmente por una varilla (3) que termina en sendos anillos de sujeción (5). Una pluralidad de pesos (6), discoidales, presentan una marca (7) de posicionamiento y una ranura (8), radial, pudiendo ser introducidos o extraídos del interior del cuerpo hueco (11) a través de una abertura (9), deslizándose libremente y de manera longitudinal a lo largo de una varilla (3) y quedando retenidos en el interior del tubo (2). Un cierre (4) en forma de anillo deslizante, es susceptible de clausurar la abertura (9), quedando sujeto a presión en posición cerrado mediante unos resaltes (12).
Patent ES-2216652-B1 (ES)
Title: Señuelo de pesca subacuatico luminoso, alimentado por pila electrica, y metodo para el mismo.
Inventor: LENDGREN PETER B
IPC: F21S10/02
Filed: 2001-05-30
Granted: 2005-12-16
Abstract: Señuelo de pesca subacuático luminoso, alimentado por pila eléctrica, y método para el mismo, que incluye, en una realización una carcasa transparente (12), que tiene por lo menos una cavidad de pila (28, 29) y por lo menos una cavidad de dispositivo fotoemisor (11a, 13a), una pila, (26, 27) dispuesta en el cavidad de pila (28, 29) y un dispositivo fotoemisor (LED) (30, 32) dispuesto en la cavidad del dispositivo. El diodo fotoemisor es preferiblemente un LED (diodo fotoemisor). La pila, en esta realización, tiene una superficie sustancialmente fotorreflectante. Un circuito eléctrico (48, 50, 44) acopla la pila y el LED. La carcasa transparente (12) tiene superficies de refracción de la luz en la misma (figura 12A) y uno o más modificadores de la luz del grupo de los elementos ópticos fotodifusores (174) (figura 13) dispersos en la carcasa y material fotorreflectante (174) (figura 14B) disperso en la carcasa.
Patent ES-2264638-B1 (ES)
Title: Sistema de control de posicion para secuencias de datos almacenadas en dispositivos digitales.
Inventor: ALACID PENALVER EDUARDO
IPC: G11B19/28
Filed: 2005-06-16
Granted: 2008-02-01
Abstract: Sistema de control de posición para secuencias de datos almacenadas en dispositivos digitales. La invención se refiere a un sistema de control de posición para secuencias de datos almacenadas en dispositivos digitales que permite aumentar la eficacia en diferentes sistemas digitales en los que es necesario editar o reproducir una secuencia de datos, que permite la localización de imágenes distantes con gran precisión basado en la relación establecida entre una vuelta completa de la rueda de control del sistema y su velocidad angular.
Patent ES-2316229-B1 (ES)
Title: Sistema para pruebas para penetracion dinamica.
Inventor: RICOL BERMEJO MANUEL
IPC: E02D1/02
Filed: 2006-03-27
Granted: 2010-01-05
Abstract: Sistema para pruebas para penetración dinámica,
basado en un dispositivo  de golpeo montado en una carcasa
protectora y unos elementos de penetración  que reciben el sucesivo
golpeo de la maza a través de una cabeza de impacto,  en el que la
cabeza (1) de impacto presenta un estrechamiento (2) definiendo  dos
regruesados (3) y (4), incorporando en el estrechamiento (2) un
cuerpo  (5) anular que se fija en proximidad a la base inferior de
la carcasa (6)  de montaje del dispositivo de golpeo, estando
accionada la carcasa (6)  por medio de una pareja de cilindros (9) y
disponiendo en proximidad a  la base inferior del cuerpo (5) anular
un fin de carrera (7) y una válvula  (8), que queda asociada a un
motor hidráulico de accionamiento del mecanismo  (12) de
elevación/liberación de la maza (13) de impacto y a la pareja de 
cilindros (9) de accionamiento de la carcasa (6).
Patent ES-2317738-B1 (ES)
Title: Pared doble divisora.
Inventor: TARRAGONA GIMENEZ RAFAEL
IPC: E04B2/30
Filed: 2005-11-11
Granted: 2009-12-23
Abstract: Pared doble divisora, del tipo de las que se
materializan en base a una  serie de piezas prefabricadas
constituidas por un núcleo cerámico con un  revestimiento, total o
parcial, de yeso o escayola, la cual se materializa  en base a unas
primeras piezas (1) prefabricadas constituidas por un núcleo 
cerámico (2) y un revestimiento (3) de yeso o escayola por una de
sus caras  mayores y por todos sus lados laterales presentando en
los vértices de  su cara mayor libre unos salientes (4), a modo de
taco, de yeso o escayola  y a unas segundas piezas (5) prefabricadas
constituidas por un núcleo cerámico  (6) y un revestimiento (7) de
yeso o escayola por una de sus caras mayores  y por todos sus lados
laterales, cuyas segundas piezas (5) se unen a las  primeras piezas
(1) a través de los salientes (4) de yeso o escayola de  sus
vértices.
Patent ES-2360678-B1 (ES)
Title: Procedimiento y dispositivo de gestiã“n de movilidad ip localizada basada en la red, red de acceso y dispositivo de pasarela de acceso fijos y mã“viles a dominios con movilidad ip localizada.
Inventor: BERNARDOS CANO CARLOS JESUS
IPC: H04L29/06
Filed: 2008-04-18
Granted: 2012-05-08
Abstract: Se propone una gestiÃ³n de movilidad IP (IPv4 o IPv6) en dominios localizados que incluyen puntos de conexiÃ³n fijos y mÃ³viles, basada en la red. El dominio localizado tiene un dispositivo receptor de todos los paquetes destinados al dominio. Este dispositivo (N-LMA) guarda en una tabla de asociaciones informaciÃ³n sobre el punto de conexiÃ³n (fijo o mÃ³vil) al que estÃ¡n conectados los nodos (terminales o puntos de conexiÃ³n mÃ³viles) en el dominio. Si el nodo estÃ¡ conectado a un punto de conexiÃ³n mÃ³vil, los paquetes se re-envÃ­an a travÃ©s del punto de conexiÃ³n fijo al que estÃ¡ conectado dicho punto de conexiÃ³n mÃ³vil. Los puntos de conexiÃ³n detectan los nodos que se conectan a ellos y lo notifican al dispositivo receptor para que actualice su tabla. AsÃ­, un terminal puede moverse en el dominio, cambiar de punto de conexiÃ³n, conectarse a un punto de conexiÃ³n mÃ³vil y moverse conectado a Ã©l, siempre sin cambiar de direcciÃ³n IP.
Patent ES-2337119-B1 (ES)
Title: Mejoras en la patente de invencion p-200703137 por "cerradura centralpara sistema de cierre multipunto con reenvios automaticos".
Inventor: GONI URBIETA FERNANDO
IPC: E05C9/02
Filed: 2008-05-19
Granted: 2011-01-04
Abstract: Mejoras en la Patente de Invención nº P
200703137 por: "Cerradura central para sistema de cierre
multipunto con reenvíos automáticos", donde la regla vertical (1)
posee una prominencia transversal (1f) estando su altura ajustada
por defecto a través de una abertura (4c) practicada en un
suplemento de nueca (4) que proyecta hacia arriba un brazo radial
(4d) que, entre sus posiciones accionada y de reposo, está impulsado
por el propio muelle recuperador (15) del picaporte de cierre (6);
dicha abertura (4c) del suplemento de nueca (4) tiene un canto
inferior (4e) sobre el que descansa un resalto inferior (1g) de la
prominencia transversal (1f) en la posición inferior de reposo de la
regla vertical (1) en conjunción con la posición de reposo del
suplemento de nueca (4) y con la posición extendida de reposo del
picaporte de cierre (6), al tiempo que esta abertura (4c) del
suplemento de nueca (4) tiene un canto superior (4f) que, con una
holgura conveniente, queda adyacente sobre un resalto superior (1h)
de dicha prominencia transversal (1f).