baber/WOPTO huggingface dataset:
Patent EP-0788373-A1 (EP)
Inventor: SZENTE LAJOS
IPC: A61K47/48
Filed: 1995-11-02
Abstract: This invention provides inclusion complexes of Taxol ((2aR-(aalpha,4beta,4alphabeta,6beta,9alpha(alphaR*,betaS*),11alpha,12alpha,12aalpha,12balpha))-beta-(benzoylamino)-alpha-hydroxy-benzene-propanoic acid 6,12-b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclo-deca-(3,4)-benz-(1,2-b)-oxeth-9-yl-ester)) or Taxotere (butoxycarbonyl-10-desacetyl-N-debenzoyl-Taxol) or Taxus extracts formed with a cyclodextrin derivative and a co-solvent. This invention relates to pharmaceutical composition with increased water-solubility and stability. This invention provides the process for the preparation of an inclusion complex of Taxol or Taxotere or a brevifolia extract of Taxus formed with a cyclodextrin derivative and a co-solvent. This invention relates to pharmaceutical composition, containing as active ingredient an effective amount of an inclusion complex of Taxol or Taxotere or a Taxus brevifolia extract formed with a cyclodextrin derivative, preferably heptakis-2,6-0 dimethyl-beta-cyclodextrin, random methylated beta-cyclodextrin, succinylmethyl-beta-cyclodextrin and a co-solvent together with usual filling, diluting and other auxiliaries generally used in the pharmaceutical industry.
Patent EP-0787102-A1 (EP)
Inventor: LYDHIG THOMAS
IPC: B65B61/20
Filed: 1995-10-26
Abstract: La présente invention concerne un procédé pour réaliser des unités d'emballage (4) pour recevoir des articles absorbants jetables tels que les protections contre l'incontinence, les serviettes hygiéniques et les couches, avec des sachets (5) dans lesquels les articles utilisés peuvent être conservés temporairement. Selon l'invention, les unités d'emballage sont pourvues d'une poche (7, 8) dans laquelle les sachets (5) sont insérés avant de remplir l'unité d'emballage avec les articles absorbants. La présente invention concerne également une unité d'emballage obtenue par le procédé de l'invention.
Patent EP-0805737-A1 (EP)
Inventor: LINDGREN MATS
IPC: B25G3/10
Filed: 1995-11-08
Abstract: PCT No. PCT/SE95/01325 Sec. 371 Date May 5, 1997 Sec. 102(e) Date May 5, 1997 PCT Filed Nov. 8, 1995 PCT Pub. No. WO96/14188 PCT Pub. Date May 17, 1996A handle for hand-held tools, particularly files, that have an end portion (3) for insertion into the handle (1). The handle includes at least two parts (4, 5) which are separated in the insertion direction of the end portion of the tool and includes end-portion guides (6). One guide has the form of a hole (6) in one handle part (4). A surface on the guide in the other handle part (5) intended for coaction with the end portion (3) of the tool is displaced laterally in relation to a corresponding surface in the hole (6). The two handle parts (4, 5) are resiliently movable relative to one another, to permit reduction in the displacement between the surfaces in conjunction with inserting the end portion (3) of the tool into the handle (1). The end portion of the tool is automatically clamped firmly in the handle as the handle parts tend to spring back to their original positions.
Patent EP-0856114-A1 (EP)
Inventor: NEVREKAR VENKATESH R
IPC: F16K3/18
Filed: 1995-10-16
Abstract: A valve assembly (100) comprises a valve body (110) having a fluid flow passageway (112-114) in communication with the valve body cavity (116) in which is disposed a flow control member (118) for selectively closing or opening the fluid flow passageway. A valve operator (150) actuates a stem (120) connected to the flow control member by a connecting means which allows axial movement of the stem (120) but substantially no rotary movement between the stem (120) and the flow control member (118). The flow control member (118) comprises stop means (130) to arrest axial movement of the stem (120) towards the flow control member (118) in order to transmit the stem force to the flow control member (118) so as to provide a better sealing function in the selected valve position. A stem moving means (152) associated with the valve operator and the steam causes the stem (120) to rotate and reciprocate. The valve operator (150) selectively moves the flow control member (118) to a flow closed position or to a flow open position.
Patent EP-0868154-A1 (EP)
Title: Implant endoluminal comportant un support structurel integral, et procede de fabrication
Inventor: EDWIN TARUN J
IPC: B29C48/13
Filed: 1995-12-08
Abstract: La présente invention concerne un implant (10) possédant une structure de support (26) qui comporte des sections de relâchement de la tension (30) se trouvant sur la surface interne, sur la surface externe, ou encore dans l'épaisseur de la paroi d'un élément de l'implant tubulaire (12). Cet implant (10) à structure de support peut comporter un élément de bordage (24) qui est co-extrudé en même temps que la structure de support (26) comportant des sections de relâchement de la tension (30), et qui est enroulé en spirales autour de l'implant tubulaire (10). La structure de support (26) comprend différents types de sections de relâchement de la tension (30) qui permettent l'expansion longitudinale et radiale, respectivement, de l'implant à structure de support. Les sections de relâchement de la tension peuvent également comprendre des extrémités libres formant des barbes (62) qui dépassent vers l'extérieur lors de l'expansion de l'implant à structure de support, et permettent d'ancrer l'implant dans un vaisseau sanguin ou une lumière du corps. Le procédé de fabrication de cet implant à structure de support consiste à choisir ou préparer une structure de support comportant des sections de relâchement de la tension, à co-extruder le support structurel en même temps qu'un élément de bordage, à former une spirale autour de l'implant tubulaire à l'aide de la structure co-extrudée, puis à fixer ladite structure co-extrudée à l'implant tubulaire.
Patent EP-0736947-A1 (EP)
Inventor: CANDATEN ALBERTO
IPC: H02H7/085
Filed: 1996-03-27
Abstract: Overload protection arrangement for a direct-current power load, adapted to be connected to a power supply source comprising a reversing switch means included in a power supply line to said power load and adapted to annihilate the difference of electric potential between the terminals of said power load through their automatically actuated connection to the same polarity of the power supply. In a preferred manner, such an overload protection arrangement is capable of being used in automatic motor-vehicle power-window or door-lock actuation systems and comprises: a polarity reversing switch; a changeover switch actuatable by a respective relay included in the power supply line and arranged to be set in a first switching position to connect a definite power-supply polarity to a definite terminal of said power load, and in a second switching position to connect the opposite polarity of the power supply to the same above cited terminal of said power load; a central control unit adapted to operate said relay.
Patent EP-0747458-A1 (EP)
Inventor: MORI OSAMU
IPC: D06M101/16
Filed: 1996-06-07
Abstract: An adhesive composition comprised of (A) a latex of 100 wt. parts of a carboxyl group-containing highly saturated nitrile-conjugated diene copolymer rubber, (B) 5 - 30 wt. parts of a resorcinol-formaldehyde resin, and (C) 2 - 10 wt. parts of an aromatic epoxy resin. A composite comprised of a nitrile group-containing highly saturated copolymer rubber and a fibrous material, which has been treated with the adhesive composition. This composite is useful for belts.
Patent EP-0790318-A1 (EP)
Inventor: GRUENEWALD WERNER
IPC: C13B10/04
Filed: 1996-06-28
Abstract: Continually-operated assembly which washes especially sugar cane fibre (11) and/or bagasse, incorporates: (a) a diffuser (10) in which the product is continually transported; (b) a fluid dispenser assembly (20) with which the imbibition liquid (21) is discharged onto the product (11) in the diffuser (10); (c) a sieve base (12) through which the imbibition fluid (21) leaves the product (11) after permeating through the product; (d) liquid collecting vessels (22) which collect the imbibition fluid (21) under the sieve base (12) percolation zone (31) of the respective diffuser (10); (e) pumps (23) which transfer fluid from the collector vessels (22) to the respective dispenser assembly (20), moving in contra-flow to the product (11). The fluid dispensers (20) are so constructed that they sprinkle imbibition fluid (21) simultaneously reaching an area of the product (11) upper surface (30), which is equivalent to at least one half pref. 100 per cent of the percolation zone area (31) of the respective collector vessel (22).
Patent EP-0765966-A1 (EP)
Inventor: BEIJAARD BAREND JACOBUS EMMANU
IPC: A22C15/00
Filed: 1996-09-27
Abstract: The invention relates to a machine frame for the meat processing industry, which can be assembled at least partly from tube profile parts (1) which tube profile parts (1) can be loaded and the outside of which comprises at least one guide surface (2) for guiding machine parts. 
     The invention also relates to a tube profile for assembling such a machine frame. Using the machine frame and the tube profile according to the invention it is possible to assemble constructions which can be cleaned very easily.
Patent EP-0780718-A1 (EP)
Inventor: ROFFMAN JEFFREY H
IPC: G02C7/04
Filed: 1996-12-20
Abstract: A design family of contact lenses includes a central area utilized for distance vision, surrounded by multiple alternating annuli of near and distance optical powers, surrounded by a peripheral distance zone. The design can also be used in intraocular contact lenses (IOC). The distance optical power is constant across the design family of lenses, but the near optical power increases as a subject's presbyopia increases. The design family of contact lenses can be fitted to a patient in a standard fashion by fitting both eyes to the best distance visual acuity (VA), and obtaining near acuity from the near annuli. A modified monovision method fits the patient's dominant eye with a contact lens as described having the full prescription distance power and fitting the nondominant eye with a contact lens as described having a distance optical power between the full prescription distance optical power and the near optical power. Specifically, the nondominant eye is fitted with a contact lens as described but having a distance power between 50% and 80% of the range between the prescription near and distance optical powers, biased towards the distance optical power.
Patent EP-0754671-A1 (EP)
Inventor: FAUCONET MICHEL
IPC: C07C57/07
Filed: 1996-07-17
Abstract: A process for the purificn. of acrylic acid obtd. by catalytic oxidn. of propylene extracted by counter-current washing of the reaction gases with a heavy hydrophobic solvent in an extn. column (C1) comprises directing the distn. flow (5) from the base of column (C1) to column (C3), and contg. the heavy extn. solvent(s), acrylic acid and impurities (mainly of b.pt. greater than that of acrylic acid), the distn. being effected in conditions such that a very pure flow of acrylic acid (6) is obtd. from the head of C3, whilst allowing some acrylic acid to pass from the base (7); feeding the effluent (7) to the lower part of a distn. column (C4) from which a lateral withdrawal at a plate between the supply and the column head is taken (9), which is rich in maleic anhydride and impurities of b.pt. between acrylic acid and the heavy solvent(s); distilling a flow (8) rich in acrylic acid from the head of (C4); and recovering a flux (1) from the base of (C4) contg. the heavy extn. solvent(s) and heavy impurities , and recycling to the head of (C1).
Patent EP-0726143-A1 (EP)
Inventor: ANDREAUS MARIO
IPC: B41F23/00
Filed: 1996-02-07
Abstract: The sheet (3) carrying a matrix array of imprints partially surrounds a rotating cylinder (4). A marker (2) is fixed to the moving member of a linear motor (1) and directed at the passing sheet. The imprints are checked by a detector (5) which verifies that any defect has been marked recognisably for purposes of subsequent processing. The marking is started by a signal to the motor to bring the marker to bear upon the sheet, and terminated by a signal for its retraction.
Patent EP-0785130-A1 (EP)
Inventor: VAN DEN BROEK ERIC
IPC: B64D17/58
Filed: 1996-01-17
Abstract: The present invention relates to a parachute release device comprising a data processing and acceleration determining means connected to said data processing system and provided for determining an acceleration parameter (6) indicating the acceleration of a falling object to which the parachute is attached, said data processing system (1) being provided for calculating from said acceleration parameter and a jump duration time an instant speed and an instant height value and for generating a release signal for opening said parachute when said instant height value reaches an opening height value.
Patent EP-0805791-A1 (EP)
Title: Process for the production of 2-(substituted benzoyl)-1,3 cyclohexanediones
Inventor: BROWN STEPHEN MARTIN
IPC: C07C315/04
Filed: 1996-01-16
Abstract: PCT No. PCT/GB96/00081 Sec. 371 Date Jun. 24, 1997 Sec. 102(e) Date Jun. 24, 1997 PCT Filed Jan. 16, 1996 PCT Pub. No. WO96/22957 PCT Pub. Date Aug. 1, 1996A process for preparing a compound of formula (I), where R1, R2, R3, R4, R5 and R6 are independently hydrogen or C1-6 alkyl; R7 is halogen, cyano, NO2, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy or RaS in which Ra is C1-4 alkyl; R8, R9 and R10 independently are hydrogen, halogen, C1-4 alkyl, C1-4 alkoxy, C1-4 haloalkyl, C1-4 haloalkoxy, CN, NO2, phenoxy or substituted phenoxy; RbS(O)n Om in which m is 0 or 1, n is 0, 1 or 2 and Rb is C1-4 alkyl, C1-4 haloalkyl, phenyl or benzyl, NHCORc in which c is C1-4 alkyl, NRdRe in which Rd and Re independently are hydrogen or C1-4 alkyl; RfC(O)- in which Rf is hydrogen, C1-4 alkyl, C1-4 haloalkyl or C1-4 alkoxy; SO2NRgRh in which Rg and Rh independently are hydrogen or C1-4 alkyl; or any two of R8, R9 and R10 together with the carbon atoms to which they are attached form a 5 or 6 membered heterocyclic ring containing up to three heteroatoms selected from 0, N or S and which may be optionally substituted by C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy, =NOC1-4 alkyl, or halogen; which process comprises the rearrangement of a compound of formula (II), where R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 are as defined in relation to formula (I), in the presence of a base and a polar aprotic solvent characterized in that the process is carried out in a reaction medium substantially free of hydrogen cyanide or cyanide anion.    <IMAGE>  (I)   <IMAGE>  (II)
Patent EP-0805644-A1 (EP)
Inventor: SEPPONEN RAIMO
IPC: A47L9/28
Filed: 1996-01-15
Abstract: The invention relates to a device for cleaning, such as a vacuum cleaner, which includes means for ionization (IG, IP) for ionization of the air flow for cleaning before it contacts with the surface to be cleaned (SC). Furthermore the device may include another means for ionization (IOG) for ionization of air to be exhausted (AF). Furthermore the device may include third means for ionization, for ionization of air to be exhausted with negative ions.
Patent EP-0808447-A1 (EP)
Title: Vorrichtung für nivellierzwecke
Inventor: GAECHTER BERNHARD
IPC: G01C15/00
Filed: 1996-01-18
Abstract: Die Erfindung betrifft eine Vorrichtung für Nivellierzwecke mit einer Abbildungsoptik, einem ortsauflösenden optoelektronischen Detektor zur Bildaufnahme und mit einer Elektronik und einer Recheneinheit zur Ansteuerung des Detektors und zur Auswertung der Detektorsignale. Die Abbildungsoptik ist in unterschiedlich abbildende Pupillenzonen für unterschiedliche Schärfentiefebereiche aufgeteilt. Den Pupillenzonen sind entsprechende Teilbereiche des Detektors zugeordnet. Die Teilbereiche des Detektors können auch durch einzelne ortsauflösende Detektoren dargestellt werden. Da eine Nivellierlatte in jeder Entfernung von dem Schärfentiefebereich einer Pupillenzone erfaßt und von dieser Pupillenzone abgebildet wird, entfällt eine manuelle oder automatisierte Nachfokussierung der Abbildungsoptik und Zielausrichtung.
Patent EP-0809867-A1 (EP)
Inventor: FAUTEUX DENIS G
IPC: H01M2/16
Filed: 1996-01-23
Abstract: An electrolytic cell (10) using small particle graphite and an electrolytic process wherein the electrolytic cell (10) includes an electrode (12) constructed with a lithium source and another electrode (14) constructed with relatively small graphite particles. The graphite particles possess physical attributes which serve to increase the reversible capacity of the graphite beyond the known theoretical capacity of 372 mAh/g of LiC6.
Patent EP-0815402-A1 (EP)
Inventor: BENSON TREVOR PAUL
IPC: F25B9/02
Filed: 1996-03-20
Abstract: La présente invention concerne un dispositif de commande (19) destiné à un réfrigérant Joule-Thomson (15). Quand ce réfrigérant (15) est refroidi à sa température de fonctionnement, le débit de gaz envoyé du réfrigérant (15) est commandé en fonction de la température ambiante de façon à maintenir ce débit à un niveau minimal.
Patent EP-0817769-A1 (EP)
Title: Novel borneol esters, process for their preparation and their pharmaceutical use
Inventor: KLAR ULRICH
IPC: C07D213/55
Filed: 1996-03-29
Abstract: PCT No. PCT/EP96/01404 Sec. 371 Date Mar. 13, 1998 Sec. 102(e) Date Mar. 13, 1998 PCT Filed Mar. 29, 1996 PCT Pub. No. WO96/32376 PCT Pub. Date Oct. 17, 1996The invention concernes borneol esters of general formula (I), in which R1 means T-C(O)-CH(OR6)-(NR7aR7b)-R8, C(O)-CH(OR6a)-CH[NR7(C(O)-CH(OR6b)-CH (NR7aR7b)-R8a)]-R8b; R7a R7b are identical or different and means R7; R7 means hydrogen, A, -C(O)R12, -C(O)OR12, -C(O)SR12, -C(O)NHR9d, -C(O)NR9dR9e, -SO2R12, C1-C10 alkyl; R8a, R8b are identical or different and mean R8; R8 means (i), heteroaryl substituted by X3, C7-C16 aralkyl, alkyl; A is B-[O-(CH2)t-C(O)]0 or 1-, farnesyl-P(O)(OR9d)-O-(CH2)t-C(O)-; B means protein kinase-inhibitors or farnesyl protein transferase-inhibitors such as for example farnesyl (ii); and T is a bond, Zi or a group (iii). The borneol esters can influence tubulin polymerisation and tubulin depolymerisation.
Patent EP-0766318-A1 (EP)
Inventor: SAKAMOTO KAZUHISA
IPC: H01L21/20
Filed: 1996-04-11
Abstract: An object of the present invention is to provide an IBGT which satisfied with a reliable high breakdown-voltage proof characteristic and occupies smaller device formation region with lower power consumption. An n-- type semiconductor layer 38 is formed on a part where has tendency to cause break down, and an n - type semiconductor substrate 36 is formed underneath the n-- type semiconductor layer 38. As a result, the value of theoretical breakdown-voltage of the n-- type semiconductor layer 38 become greater than that of the n - type semiconductor substrate 36. Also, the n - type semiconductor substrate 36 having lower electric resistance is located underneath the n-- type semiconductor layer 38. Therefore, lower power consumption is expected because electric resistance of the part where determines a power consumption of the IGBT is decreased.
Patent EP-0820645-A1 (EP)
Inventor: LITWIN ANDREJ
IPC: H01L29/732
Filed: 1996-04-09
Abstract: Transistor bipolaire a silicium sur isolant, comprenant un substrat (1) présentant une face principale, une couche d'oxyde (2) sur ladite face principale, une couche de silicium (3) d'un premier type de conductivité sur ladite couche d'oxyde (2), une région base (4) d'un deuxième type de conductivité s'étendant vers l'intérieur de la couche de silicium (3), une région émettrice (5) à conductivité du premier type s'étendant vers l'intérieur de la région base (4), une région collectrice (6) à conductivité du premier type s'étendant vers l'intérieur de la couche de silicium (3) à une certaine distance latérale à partir de la région base (4), une région de connexion (8) à conductivité du deuxième type s'étendant vers l'intérieur de la couche de silicium (3) jusqu'à la couche d'oxyde (2) du côté opposé de la région émettrice (5) par rapport à la région collectrice (6), une partie (8') de ladite région de connexion (8) s'étendant latéralement selon la surface de la couche d'oxyde (2) sous une partie au moins de la région émettrice (5) en direction de la région collectrice (6) à une certaine distance de la région base (4). La région de connexion est reliée électriquement à la région base (4).
Patent EP-0825985-A1 (EP)
Inventor: REICHWEIN ADRIANUS MARIA
IPC: C07B61/00
Filed: 1996-04-24
Abstract: PCT No. PCT/EP96/01730 Sec. 371 Date Nov. 13, 1997 Sec. 102(e) Date Nov. 13, 1997 PCT Filed Apr. 24, 1996 PCT Pub. No. WO96/36607 PCT Pub. Date Nov. 21, 1996A process has been found for preparing pyridine-2,6-diamines, i.e., 2,6-diaminopyridine (DAP) and derivative compounds in which one of the amino groups is a substituted amine (secondary or tertiary). According to this process, 3-hydroxy pentane 1,5-dinitrile (3-hydroxyglutaronitrile) is reacted with an ammonium donor in the form of ammonia, a primary amine such as n-butylamine, or a secondary amine such as piperidine.
Patent EP-0824548-A1 (EP)
Inventor: HOLMGREN JAN
IPC: C07K14/245
Filed: 1996-05-02
Abstract: Hybrid molecules between heat-labile enterotoxin B subunit (LTB) and cholera toxin B subunit (CTB) are disclosed. Such a hybrid molecule comprises an amino-acid sequence which is composed of the amino-acid sequence of mature CTB in which such amino-acid residues are substituted with the corresponding amino-acid residues of mature LTB which impart LTB-specific epitope characteristics to said immunogenic mature CTB, or vice versa. In addition, a structural gene coding for such a hybrid molecule, a plasmid containing such a structural gene, and an immunogenic protein comprising such a hybrid molecule and optionally an immunoreactive amino-acid sequence of a prokaryotic or eukaryotic cell or a virus, are disclosed. Disclosed is also a vaccine, e.g. against enterotoxin-induced illness, comprising such an immunogenic protein, and a method of preventing or treating enterotoxin-induced illness in an individual.
Patent EP-0846267-A1 (EP)
Inventor: SWEDO SUSAN E
IPC: G01N33/68
Filed: 1996-06-06
Abstract: A method of identifying individuals who have, or who are at risk of developing, autoimmune neuropsychiatric disorders is disclosed. The invented method relies on detection of the B lymphocyte antigen, D8/17. The invented method can conveniently be carried out as a simple blood test.
Patent EP-0828537-A1 (EP)
Title: Foaming composition and use thereof as a fire-extinguishing foam
Inventor: BARBARIN MICHEL
IPC: C09K23/56
Filed: 1996-05-31
Abstract: A foaming composition containing one or more fluorinated surfactants and one or more alkylpolyglycoside hemisulphosuccinate surfactants of formula (I) is described, wherein R is a straight or branched chain alkyl radical with 6-18 carbon atoms, S is a sugar residue, one of R1 and R2 is a SO3M group, and the other a hydrogen atom, M is an alkali metal, preferably sodium, X is an integer of 1 to 10, preferably of 1 to 4. The use of said foaming composition as a fire-extinguishing foam is also described.
Patent EP-0833935-A1 (EP)
Inventor: SAYDOFF JOEL
IPC: A61K48/00
Filed: 1996-06-07
Abstract: A genetically engineered cell line that produces at least one catecholamine, at least one endorphin, and at least one enkephalin, for the treatment of pain. The cells may be provided directly to a patient in need thereof, or encapsulated to form a bioartificial organ.