baber/WOPTO huggingface dataset:
Patent CA-3081937-A1 (CA)
Title: Type v crispr/cas effector proteins for cleaving ssdnas and detecting target dnas
Inventor: DOUDNA JENNIFER A
IPC: C12Q1/68
Filed: 2018-11-20
Abstract: Provided are compositions and methods for detecting a target DNA (double stranded or single stranded) in a sample. In some embodiments, a subject method includes: (a) contacting the sample with: (i) a type V CRISPR/Cas effector protein (e.g., a Cas12 protein such as Cas12a, Cas12b, Cas12c, Cas12d, Cas12e); (ii) a guide RNA (comprising a region that binds to the type V CRISPR/Cas effector protein, and a guide sequence that hybridizes with the target DNA); and (iii) a detector DNA that is single stranded (i.e., a "single stranded detector DNA") and does not hybridize with the guide sequence of the guide RNA; and (b) measuring a detectable signal produced by cleavage (by the type V CRISPR/Cas effector protein) of the single stranded detector DNA. Also provided are compositions and methods for cleaving single stranded DNAs (e.g., non-target ssDNAs), e.g., inside of a cell.
Patent CA-3082138-A1 (CA)
Inventor: PIKE LEE
IPC: C22F1/10
Filed: 2018-11-09
Abstract: In a method for heat treating alloy compositions within UNS N07028 the alloy composition is heated at a temperature between 1550°F and 1750°F for at least two hours, and then heated at a lower temperature between 1300°F and 1550°F for at least two hours. The alloy composition may be heated at a temperature between 1850°F and 1950°F for at least one hour before heating the alloy composition at a temperature between 1550°F and 1750°F.
Patent CA-3085309-A1 (CA)
Inventor: PERSSON TOMAS
IPC: A41D31/30
Filed: 2018-12-19
Abstract: The present invention aims to provide a fabric useful in production of clothesand other textile articles, in particular for use in a healthcare environment such as hospitals, long term care facilities, etc. The invention relates to a yarn consisting essentially of cotton fibres, hemp fibres, and fibres comprising porous particles, and to threads and fabrics comprising such yarns, as well as to the use of such clothing as healthcare staff uniforms.The yarn and fabric may further include at least one metal wire usable as a temperature sensor.
Patent CA-3085323-A1 (CA)
Title: Personal care compositions
Inventor: DEWDNEY NADINE
IPC: A61K8/92
Filed: 2018-12-13
Abstract: Disclosed herein are liquid cleansing compositions comprising a foam booster comprising ethoxylated hydrogenated castor oil present in an amount ranging from about 0.5% to about 2% based on the total weight of the composition, castor oil maleate, glycerin, and at least one surfactant, wherein the pH of the composition is less than about 7. The liquid cleansing compositions disclosed herein provide enhanced foam volume and texture. Further disclosed herein are methods of making a liquid cleansing composition.
Patent CA-3089876-A1 (CA)
Title: Dynamic support apparatus and system
Inventor: STREETER ALEXANDER D
IPC: A61F2/68
Filed: 2013-05-01
Abstract: ABSTRACT A control unit system for providing support to a user. The system includes at least two groups of at least one bladder. The system also includes a control unit which includes at least one actuator, a detachable manifold comprising at least one magnet fluidly coupling the at least two groups of at least one bladder to the at least one actuator, a pump connected to the at least one actuator for causing actuation thereof, a control system for controlling the pump wherein the control system controls the pump to actuate the at least one actuator at least in response to a signal received by the control system, and a switch configured to toggle the pump actuation between a first group and a second group of at least one bladder. Date Recue/Date Received 2020-08-12
Patent CA-3091701-A1 (CA)
Title: Lactose free milk products
Inventor: HOBBA GRAHAM DEAN
IPC: A23C9/14
Filed: 2018-03-05
Abstract: Described herein are liquid, concentrated or dried lactose-free skim milk products or lactose- free, fat containing milk products that exhibit stability during thermal processing and storage as a result of the reductive carbohydrate to milk protein ratio of the milk products. The osmolality of the lactose-free milk products described herein also enable improved nutritional availability when compared to commercially available lactose hydrolysed milk products.
Patent CA-3093715-A1 (CA)
Inventor: KRIEG ARTHUR M
IPC: C12N15/117
Filed: 2019-04-19
Abstract: La présente invention concerne, entre autres, des molécules d'ARN (par exemple, des agonistes d'ARN en épingle à cheveux) qui se lient à des récepteurs de type RIG-I et ont un effet agoniste (RLR), et l'utilisation des molécules dans des méthodes pour traiter ou améliorer un ou plusieurs symptômes d'un trouble (par exemple, un cancer).
Patent CA-3093784-A1 (CA)
Inventor: OBLIGER NICOLAS
IPC: A47J31/36
Filed: 2019-03-13
Abstract: A machine (1) for preparing a beverage from an ingredient includes an extraction unit (2) that has: an ingredient extraction seat (20); an inlet arrangement (21) for guiding water into the seat (20); and a dispensing arrangement (22) for guiding beverage out of the seat (20). The dispensing arrangement (22) has a face (220) delimiting a downstream part of the seat (20) and having a flow-through portion (221) configured such that beverage flowing out the seat (20) flows through the flow-through portion (221) towards a beverage dispensing area (1'). The face (220) has a flow-inhibiting portion (222, 222a, 222b, 222c) that is at least substantially flush with the flow-through portion (221) so as to delimit the seat (20). The flow-inhibiting portion (222, 222a, 222b, 222c) is configured such that beverage flowing out the seat (20) is inhibited, e.g. prevented, from passing through the flow-inhibiting portion (222, 222a, 222b, 222c).
Patent CA-3093991-A1 (CA)
Title: Systems and methods for intelligent event waveform analysis
Inventor: MENZEL JOHANNES
IPC: H02J3/00
Filed: 2019-04-04
Abstract: In a method and system, voltage and/or current signals on an electrical/power system is monitored. A power event is identified from the monitored voltage and/or current signals. In response to event identification, waveforms of the monitored voltage and/or current signals are captured. Energy-related signals are calculated and extracted from pre-event measurements, event measurements and post-event measurements using the captured waveforms. Additional information associated with the event is identified and calculated by comparing (a) the calculated and used energy-related signals from pre-event measurements, with (b) the calculated and used energy-related signals from post-event measurements.
Patent CA-3097767-A1 (CA)
Inventor: CANEPARI LUIS
IPC: E21C47/00
Filed: 2019-03-01
Abstract: A precision mining system having mining equipment manipulable to recover material with mineral resources, the system comprising: an image sensor for capturing real-time imagery of a geographical location having material with mineral resources and at least one element of the mining equipment; a storage device comprising instructions and the real-time imagery; and a processor configured to execute the instructions to receive, from the image sensor, real-time imagery; at least one sensing device associated with at least one element of the mining equipment configured to acquire data corresponding to at least one of position and motion of at least one element of the mining equipment in the real-time imagery; and the processor configured to execute the instructions to generate at least one production polygon corresponding to a volume of interest with the mineral resources and combine the real-time imagery with at least one production polygon to generate real-time composite imagery.
Patent CA-3098256-A1 (CA)
Inventor: DE SOUZA TEIXEIRA LEONARDO
IPC: A61K9/00
Filed: 2019-04-25
Abstract: The present invention relates to a topical pharmaceutical composition to be used in the anal region for anal fissures and hemorrhoids, including the postoperative period of hemorrhoidectomy. The pharmaceutical composition comprises an anal dilator, a mucoadhesive polymer and a non-aqueous vehicle. Also described is a method of manufacturing the pharmaceutical composition.
Patent CA-3100357-A1 (CA)
Inventor: JOHNSON KARL ERIC
IPC: H02P27/04
Filed: 2020-11-23
Abstract: Un manipulateur de matériau comprend un moteur, un dispositif dinterface et un contrôleur. Le contrôleur est configuré pour recevoir une entrée du dispositif dinterface, et il peut comprendre un entraînement à fréquence variable. Le contrôleur fournit un signal dentraînement à fréquence variable au moteur pour contrôler le déplacement dau moins une pièce du manipulateur de matériau. Si le dispositif dinterface est inactif pendant une durée prédéterminée, le contrôle ajuste une fréquence du signal dentraînement à fréquence variable dune fréquence de fonctionnement à une fréquence en attente inférieure à la fréquence de fonctionnement. Lajustement de la fréquence, de la fréquence de fonctionnement à la fréquence en attente, peut comprendre lajustement de la fréquence du signal dentraînement à fréquence variable à au moins une fréquence intermédiaire. Au moment dajustement de la fréquence du signal dentraînement à fréquence variable, le contrôleur peut sauter au moins une fréquence, ou au moins une gamme de fréquences, comme pour éviter des caractéristiques de fonctionnement non désirées.
Patent CA-3103188-A1 (CA)
Title: Rapid ore analysis to enable bulk sorting using gamma-activation analysis
Inventor: COGHILL PETER
IPC: H05G1/00
Filed: 2020-12-17
Abstract: Abstract An apparatus for bulk ore sorting using gamma activation analysis is disclosed. The apparatus includes a conveyor system that includes one or more conveyor belts, surrounded by one or more radiation shields, to transport ore material along a transport path. A pulsed X-ray radiation source is configured to irradiate ore material at an irradiation region and one or more detectors are configured to detect a gamma radiation output from irradiated ore material at a detection region. The transport path has a bend, located between the irradiation region and the detection region, and about a vertical axis, of at least 45 degrees. The one or more detectors are configured to detect a radiation output from the irradiated ore material at times between X-ray pulses of the pulsed X-ray radiation source irradiating the ore material. Date Recue/Date Received 2020-12-17
Patent CA-3107370-A1 (CA)
Inventor: LUTHMAN JOHAN
IPC: A61P25/28
Filed: 2019-07-23
Abstract: Provided herein are methods of reducing clinical decline in a subject having early Alzheimer's disease, methods of converting an amyloid positive subject having early Alzheimer's disease to amyloid negative, methods of reducing brain amyloid level in a subject, and methods of preventing Alzheimer's disease, the methods comprising administering a composition comprising a therapeutically effective amount of at least one anti-Aß protofibril antibody. In some embodiments, the subject is ApoE4-positive. In some embodiments, the at least one anti-Aß protofibril antibody is BAN2401.
Patent CA-3110253-A1 (CA)
Title: Thread catching and engaging tamper evidence closure
Inventor: HANAN JAY CLARKE
IPC: B65D41/04
Filed: 2019-08-21
Abstract: A tamper evidence closure is provided for engaging with a finish so as to seal contents within the interior of a container. The tamper evidence closure comprises interior threads configured to engage with threads of a finish. A tamper evidence portion is disposed around the perimeter of a lower portion. Recesses are configured to receive and fixate thread ends disposed on the finish so as to prevent further rotation of the tamper evidence portion and configured to be outwardly flexed by the finish. Each of tamper evidence flaps includes a ramp that terminates at a catching surface that is configured to be contacted by a truncated thread end of the finish during loosening of the closure by an end-user. The tamper evidence band on the finish and the flaps are configured to remain in absence of the finish to indicate that the tamper evidence closure has been previously loosened.
Patent CA-3113363-A1 (CA)
Title: Mechanical computing systems
Inventor: MERKLE RALPH C
IPC: G06C15/00
Filed: 2015-12-31
Abstract: ABSTRACT Systems and methods for creating mechanical computing mechanisms and Turing- complete systems which include combinatorial logic and sequential logic, and are energy- efficient. Embodiments of the invention include mechanical computing mechanisms and computational systems which have lower energy dissipation, a smaller number of basic parts, and other advantages over previous systems. Multiple embodiments are disclosed including mechanical link logic, mechanical flexure logic, and mechanical cable logic, along with design paradigms (including both mechanical designs, principles, and a novel classification system which categorizes systems as Types 1 through 4) that teach how to apply the general principles to other embodiments. Date Recue/Date Received 2021-03-26
Patent CA-3113786-A1 (CA)
Inventor: RIMMER JULIAN
IPC: E04B9/00
Filed: 2019-10-18
Abstract: A ceiling beam grid is an open grid constructed from beams of a few standard sizes that are connected together by connection blocks at the intersections of the beams. The connection blocks are suspended from the structural ceiling of the room by means of an anchor and hanger and are spaced in a grid pattern to accommodate the standard size beams between adjacent connection blocks. The standard size beams are then attached to and supported between the connection blocks. The beams are connected to the connection blocks by a vertical tongue and groove connection. The tongue and groove connection provides a sliding connection that allows the beams to be easily connected and disconnected from the connection blocks without the need of tools. Consequently, the ceiling beam grid can be easily reconfigured to accommodate changes in the room below.
Patent CA-3114300-A1 (CA)
Title: Bi-fuel reciprocating engine to power direct drive turbine fracturing pumps onboard auxiliary systems and related methods
Inventor: YEUNG TONY
IPC: F02M25/00
Filed: 2021-04-07
Abstract: Systems and methods for supplying primary fuel and secondary fuel to an internal combustion engine may include supplying a first amount of the primary fuel and a second amount of the secondary fuel to the internal combustion engine. The system may include a first manifold to provide primary fuel to the internal combustion engine, and a primary valve associated with the first manifold to provide fluid flow between a primary fuel source and the internal combustion engine. A second manifold may provide secondary fuel to the internal combustion engine, and a fuel pump and/or a secondary valve may provide fluid flow between a secondary fuel source and the internal combustion engine. A controller may determine a total power load, the first amount of primary fuel, and the second amount of secondary fuel to supply to the internal combustion engine to meet the total power load.
Patent CA-3117314-A1 (CA)
Title: Secure invocation of network security entities
Inventor: OBER TIMOTHY F
IPC: G06F21/53
Filed: 2018-11-07
Abstract: A method of enforcing, deploying and invoking network security includes identifying a plurality of computing entities adapted for invocation on a network entity in an interconnected network, such that each network entity is adapted to launch and execute at least one network conversant app. An agent deploys the identified security entity on a target network entity or node, such that the security entity is responsive to the security agent previously deployed on the network entity. Upon deployment and launch, a security manager in communication with each of the security entities receives an indication of security entity operation. The security entity is thereafter enabled to scrutinize network traffic by evaluating the identified data upon ingress or egress to determine a security event, and to communicating with the security manager to provide consistent continued instantiation of the security entity.
Patent CA-3119843-A1 (CA)
Title: Systems, devices, and methods for adjusting blood flow in a body lumen
Inventor: BENARY RAPHAEL
IPC: A61B5/0215
Filed: 2019-12-11
Abstract: [0059] Embodiments of the present disclosure are directed to blood-flow regulation systems and associated methods, and, in some embodiments, includes an adjustable blood flow regulation device that includes an inner tube, an expandable member coupled to the inner tube, a proximal control handle that includes a controller operatively coupled to the member and configured to control expansion of the member, and a downstream tip member coupled to a distal portion of the inner tube which is distal to the member. The tip member is coupled to a first fluid pressure sensor. A second fluid pressure sensor is coupled to a portion of the inner tube proximal to the member.
Patent CA-3120278-A1 (CA)
Title: Satellite communication system and method for pointing error resistent reuse
Inventor: KAY STANLEY EDWARD
IPC: H04B7/185
Filed: 2019-11-17
Abstract: Systems and methods are disclosed, and one includes receiving a configuration specification data, including a cell floorplan data identifying a plurality of rectangular cells, and indicating a cell width and a cell length of each, in combination with determining, based at least in part on the configuration specification data, a spot beam pattern that provides a plurality of rectangular cell coverage regions, having the cell length and width.
Patent CA-3120741-A1 (CA)
Title: Carbon nanomaterial for use as a catalyst
Inventor: KRUUSENBERG IVAR
IPC: H01M4/90
Filed: 2019-11-22
Abstract: A method for producing a carbon nanomaterial for use as a catalyst, including the steps of: (a) providing a precursor which is a source of lignin, (b) heating the precursor to an activation temperature from 700°C to 800°C in the presence of an alkali solution in order to produce an activated precursor, and (c) reacting the activated precursor with a source of nitrogen atoms in order to dope the activated precursor with nitrogen atoms, wherein the precursor is heated in step (b) to the activation temperature at a rate of at least 500°C per minute.
Patent CA-3122661-A1 (CA)
Title: Decorative respirator and communication mask
Inventor: BOUSSEY RILEY
IPC: A62B18/00
Filed: 2021-06-17
Abstract: A face mask is provided. A face mask comprising a decorative skin, having a strap attached to an outer perimeter of the decorative skin, a respirator attached to a connection piece and utilizes a filter, the connection piece being attached to the decorative skin, a speaker and a microphone mounted to an interior of the face mask, an electronic transceiver module attached to the face mask and a power source attached to the face mask. The strap secures the face mask to a head of the user, the filter is connected to the respirator such that an air-tight seal is formed. The power source powers the speaker, the microphone, and the electronic transceiver module. The electronic transceiver module comprises a processor coupled to a computer memory and non-transitory computer readable media, the processor configured to transmit and receive signals from the electronic transceiver module and the speaker or microphone.
Patent CA-3124923-A1 (CA)
Title: Vane pump having hollow pivot pin with fastener
Inventor: SHI LIXIA
IPC: F04C15/00
Filed: 2019-11-21
Abstract: Disclosed is a vane pump including a housing, a pivot pin having a hollow portion mounted within the housing, a control slide displaceable about the pivot pin within the housing between a first slide position and a second slide position to adjust displacement of the pump through an outlet, and a cover attached to the housing via a fastener passing through the pivot pin such that the control slide rotates about the pivot pin with respect to the housing and the cover. In an example, the fastener passes through to the engine mount. The pivot pin does not create a fluid path through the hollow portion.
Patent CA-3129183-A1 (CA)
Inventor: RODRIGUEZ YAN
IPC: H04W84/18
Filed: 2021-08-27
Abstract: An example control system includes a set of light fixtures connected to a hub, where each light fixture includes a hub-communication device configured to communicate with the hub and a direct communication device configured to communicate directly with other light fixtures.  Together, the light fixtures form a mesh network facilitated by the use of their direct communication devices. An external device communicates an instruction to a light fixture, and the instruction is propagated throughout the mesh network through communications among the light fixtures using their respective direct communication devices. As a result, each light fixture to which the instruction applies receives and complies with the instructions.  The light fixtures are also configured to receive instructions from the hub, such that a light fixture is configured to receive instructions over dual networks.
Patent CA-3129683-A1 (CA)
Title: Method and apparatus for manufacturing a workpiece into a product
Inventor: LE CLEC'H JULIEN
IPC: B23K26/08
Filed: 2020-02-26
Abstract: The invention relates to a method and an apparatus for manufacturing a workpiece (101), specifically a rough diamond, into a product (102), specifically a brilliant. The method is performed by an apparatus providing a laser beam (103) coupled into a pressurized fluid jet (104). The method comprises executing multiple cuts of the workpiece (101) with the laser beam (103) according to a predetermined cut-sequence to remove workpiece (101) material with each completed cut. The method further comprises executing multiple rotations of the workpiece (101) around the same axis (106) of revolution according to a predetermined rotation-sequence (107). Thereby, a rotation is executed after a completed cut, and for executing a cut the laser beam (103) is moved along a two- dimensional path (108).
Patent CA-3130713-A1 (CA)
Title: Combination of nitazoxanide and elafibranor for the treatment of immune diseases or inflammation
Inventor: PARROCHE PEGGY
IPC: A61K31/192
Filed: 2020-04-07
Abstract: The present invention relates to a combination product comprising (i) nitazoxanide (NTZ) or an analogue thereof, and (ii) a PPAR agonist, for use in the treatment of an immune diseasesor inflammation.
Patent CA-3131774-A1 (CA)
Inventor: YAMAMOTO YOSUKE
IPC: C07K1/00
Filed: 2020-02-25
Abstract: L'invention concerne : un procédé de production d'un composé peptidique, le procédé comprenant une étape d'utilisation d'un composé hétérocyclique aromatique représenté par la formule (1) ; un réactif formant un groupe protecteur contenant ledit composé ; et ledit composé. Dans la formule (1), le cycle A représente un cycle hétérocyclique aromatique, les fractions YA représentent chacune indépendamment -OH, -NHR, -SH ou -X0, X0 représente Cl, Br ou I, les fractions RA et RC représentent chacune indépendamment un groupe hydrocarboné aliphatique ou un groupe organique ayant un groupe hydrocarboné aliphatique, les fractions RB représentent chacune indépendamment un groupe hydrocarboné aliphatique monovalent, un groupe aromatique de valence (1+c) ou un groupe hétéroaromatique de valence (1+c), RB est un groupe hydrocarboné aliphatique monovalent dans le cas où les deux a et c valent 0, et le nombre d'atomes de carbone dans le groupe hydrocarboné aliphatique dans au moins l'un de RA, RB et RC est de 12 ou plus.
Patent CA-3132290-A1 (CA)
Title: Indicators for hybrid electrical powerplants
Inventor: KRENZ MICHAEL
IPC: B64D27/24
Filed: 2019-12-10
Abstract: An indicator for a hybrid electric powerplant for an aircraft can be configured to indicate at least an amount or percentage of a total power and/or total torque, and an amount or percentage of an electric motor power and/or electric motor torque. For example, the indicator can be a graphical user interface (GUI) of an aircraft cockpit display.