baber/WOPTO huggingface dataset:
Patent CA-2553593-A1 (CA)
Title: Sampling and assay device
Inventor: GRANBERG CHRISTER
IPC: C12M1/30
Filed: 2005-01-19
Abstract: A sampling and assay device comprises at least three chamber portions (1, 3, 4) connected together in a row. Each chamber portion (1, 3, 4) defines a chamber (11, 13, 27) and adjacent chambers (11, 13, 27) along the row are separated by respective partitions (14, 15). One end chamber (4) is capable of receiving a sample either on a swab or as a liquid. The other chambers (11, 13) contain reagent for performing the assay. Adjacent chamber portions (1, 3, 4) along the row are relatively movable towards each another. In respect of each pair of adjacent chamber portions (1, 3), one of the adjacent chamber portions (1) has the respective partition (14) fixed thereto and the other of the adjacent chamber portions (3) has a rupture member (17) arranged to rupture the respective partition (14) on relative movement of the adjacent chamber portions (1, 3). As a result, the sampling and assay device is capable of rupturing each partition (14, 15) simultaneously on relative movement of the chamber portions (1, 4) at the ends of the row towards each other. Also, each pair of adjacent chamber portions (1, 3) have respective connection portions (2a, 3a) mated together, the connection portions (2a, 3a) being designed to allow further chamber portions identical to an intermediate chamber portion to be connected into said row.
Patent CA-2555632-A1 (CA)
Title: Inhibition of protein kinase c-related kinase (prk) as a treatment for cardiac hypertrophy and heart failure
Inventor: MCKINSEY TIMOTHY A
IPC: C12Q1/68
Filed: 2005-02-02
Abstract: The present invention provides for methods of treating and preventing cardiac hypertrophy and heart failure. MEF-2 and Class II HDACs have been shown to have a major role in cardiac hypertrophy and heart disease, and inhibition of class II HDAC's has been shown to have a beneficial, anti-hypertrophic effect.  The present invention provides a link between MEF-2 and class II HDAC's, a kinase known as PRK. The present invention further demonstrates that inhibitors of PRK inhibit cardiac hypertrophy and heart disease by inhibiting, in part, the fetal cardiac gene expression and cellular reorganization that occurs when MEF-2 dependent transcription is activated.
Patent CA-2557126-A1 (CA)
Inventor: GENNASIO ENRICO
IPC: B21D41/02
Filed: 2005-01-18
Abstract: A fitting (1) for high-pressure pipes (4) comprises means (2) for holding a nut (3) at the end of a high-pressure pipe (4) defined by at least one deformation (5) of the walls of the end zone of the pipe (4) and reaction means (6) for keeping the deformation (5) substantially unaltered.
Patent CA-2558314-A1 (CA)
Title: Use of pde iii inhibitors for the reduction of heart size in mammals suffering from heart failure
Inventor: KLEEMANN RAINER
IPC: A61K31/501
Filed: 2005-03-19
Abstract: The invention relates to the use of a phosphodiesterase type III (PDE III) inhibitor or Ca2+ -sensitizing agent or a pharmaceutically acceptable derivative thereof for the preparation of a medication for the reduction of the heart size of a patient suffering from heart failure.
Patent CA-2558565-A1 (CA)
Title: Collapsible/expandable tubular electrode leads
Inventor: WALLACE MICHAEL P
IPC: A61N1/05
Filed: 2005-03-01
Abstract: A medical lead comprising an electrically insulative tubular membrane, a resilient spring element associated with the insulative membrane, and at least one electrode associated with the insulative membrane. The tubular membrane may have a non-circular cross-sectional shape. The spring layer is configured to urge that insulative membrane into an expanded geometry. The medical lead may be configured to be collapsed into a compact form for percutaneous delivery into the patient.
Patent CA-2561468-A1 (CA)
Title: Floating foam for fire fighting
Inventor: ELLIOT MARK
IPC: A62D1/02
Filed: 2006-09-28
Abstract: Foams and methods of using foams for fighting fires in confined areas (i.e., mine shafts) are provided. In one embodiment, a foam for extinguishing a fire is provided. The foam includes a surfactant; a non-flammable liquid; and an inert gas having a density substantially less than air. Preferably, the density of the foam is substantially less than the density of air. The light foam will allow a basic form of directional control of the foam because the light foam will float towards the ceiling of a cavern or mine shaft. This offers fire fighters several options in extinguishing an underground fire.
Patent CA-2561856-A1 (CA)
Inventor: CROWLEY MICHAEL M
IPC: A61K33/10
Filed: 2005-03-31
Abstract: An oral solid compress composition comprising a magnesium salt is provided.  The composition provides a rapid dissolution of the magnesium salt, wherein not less than 75% of the magnesium salt dissolves within 45 minutes after placement in hydrochloric acid (0.1 N, 900 mL) as per USP Method <711>. In a particular embodiment, the magnesium salt is an inorganic salt such as MgO, Mg(OH)2, MgCl2, and others. The composition can be prepared by dry granulation, direct compression or another suitable process. The composition provides a substantially stable dissolution profile for the magnesium salt so that the dissolution profile changes only minimally even after an extended period of storage under pharmaceutically acceptable conditions when packaged in a sealed container-enclosure system. The solid composition may also exclude a cellulose-based composition. The compressed composition can be prepared and stored under anhydrous conditions.
Patent CA-2562222-A1 (CA)
Inventor: KIELLAND PETER JOHANN
IPC: B62K11/00
Filed: 2006-09-26
Abstract: The invention is a kit for converting a conventional Electric Assist Bicycle (EAB) into a dual-posture (upright and recumbent) vehicle that optimizes the characteristics of the EAB's electric-assist propulsion system. The kit is comprised of three bolt-on components: a backrest assembly, a footrest assembly and an extended handlebar assembly which together enable the user to assume either a normal upright posture (for pedal-assisting the bicycle's electric motor) or else recline into a more comfortable and aerodynamic recumbent posture (that permits the motor to provide all of the vehicle's propulsive energy). The modified EAB's inclined backrest is typically affixed to the bicycle's seatpost. Left and right footrests are affixed near the bicycle's headtube using a universal-fit clamping fixture. Said footrests are used during recumbent operation to support the user's feet up and away from the bicycle's pedal crank. The extended handlebar typically includes means for quickly repositioning the controls while under way to provide an ergonomic bar position for whichever seating posture is being used.
Patent CA-2562581-A1 (CA)
Title: Electronic atomization cigarette
Inventor: HON LIK
IPC: A24F40/05
Filed: 2005-03-18
Abstract: The present invention relates to an electronic atomization cigarette which only contains nicotine without harmful tar. The electronic atomization cigarette includes a shell and a mouthpiece. The external wall of the shell has an air inlet. An electronic circuit board, a normal pressure cavity, a sensor, a vapor-liquid separator, an atomizer, a liquid-supplying bottle are sequentially provided within the shell, wherein the electronic circuit board comprises an electronic switching circuit and a high frequency generator. A stream passage of the sensor is provided on one side of the sensor, and a negative pressure cavity is provided in the sensor. The atomizer and the liquid-supplying bottle is in contact with each other. An atomization cavity is arranged in the atomizer. A retaining ring for locking the liquid-supplying bottle is provided between one side of the liquid-supplying bottle and the shell, and an aerosol passage is provided on the other side of the liquid-supplying bottle. The air inlet, normal pressure cavity, vapor-liquid separator, atomizer, aerosol passage, gas vent and mouthpiece are sequentially interconnected. The advantages of the present invention include smoking without tar, significantly reducing the cancerogenic risk. Furthermore, users still feel as if they are smoking and experiencing the same excitement, and the cigarette is no need to be lit and is no fire risk.
Patent CA-2563365-A1 (CA)
Inventor: SULLIVAN TIMOTHY R
IPC: A01N63/00
Filed: 2005-04-25
Abstract: The present disclosure is directed to devices that administer single or multiple doses of one or more substances to the eye, nose, or ear of a user. The precise and repeatable dosing features of the presently disclosed devices overcome many of the disadvantages associated with known methods for dispensing substances to, for example, the eye of a user. The devices administer precise doses of a substance to a precise location from ampoules that may be single-dose or two-dose ampoules, which may be externally or internally pierced.
Patent CA-2563580-A1 (CA)
Title: Expandable tubular connection
Inventor: ADAM MARK K
IPC: E21B43/10
Filed: 2005-04-19
Abstract: An expandable tubular pin (10) and box (12) connection is described having a feature of trapping the pin nose (26) after preferably deforming the pin nose (26) plastically in an outward direction away from the longitudinal axis (20) of the connection. The box end (32) is held away from the pin wall (34) before expansion so that its tendency to curl inwardly upon expansion causes it to bend against the pin wall (34) for sealing with it. The thread profile (14, 16) is also optimized to reduce flank separation as a result of expansion.
Patent CA-2563904-A1 (CA)
Inventor: WILSON ROSS PHILLIP
IPC: G01N33/53
Filed: 2004-04-29
Abstract: The present invention relates to isolated canine animal plasma, a method for isolating canine animal plasma, plasma obtained form an immunised or hyperimmunised canine animal and treating a canine animal with the isolated canine animal plasma. The method includes the step of selecting a canine animal having a blood group compatible with a recipient canine animal having an unmatched blood group, namely, selecting a canine animal for a blood group that does not cause plasma transfusion reaction and/or haemolysis. In one form, the method includes the step of immunising or hyperimmunising a canine animal plasma donor with one or more antigens of a canine animal pathogen. The pathogen is preferably a bacteria or virus.
Patent CA-2566907-A1 (CA)
Inventor: TSAUR LIANG SHENG
IPC: A61K8/36
Filed: 2005-04-25
Abstract: Personal product liquid cleansing compositions for delivering benefit agents such as moisturizers. A technical problem with such cleansers is that cleansing ingredients, in general, tend to be incompatible with moisturizing ingredients, which makes the compositions difficult to formulate.                                                        Disclosed are liquid cleansers which comprise water soluble or water swellable starch combining with linear C8 to C13 fatty acid to structure the composition and prevent phase separation. The compositions of the invention are stable both at room temperature and at 45°C for over three weeks with no visible phase separation.
Patent CA-2566955-A1 (CA)
Inventor: OTTOW MANFRED
IPC: B65G65/46
Filed: 2006-11-02
Abstract: The invention pertains to a method and a device for discharging poorly pourable bulk materials such as, in particular, sawdust, splinters and wood chips from a receptacle. According to the invention, the poorly pourable bulk material in the receptacle is rendered free-flowing by means of a first helical agitating element and discharged from the receptacle by means of a second helical agitating element. In this case, it is particularly advantageous that the first helical agitating element and the second helical agitating element are mechanically coupled to one another such that only one drive is required for both agitating elements. The first agitating element consists of a shaft and a worm conveyor, and the second agitating element consists of a shaft and a spiral conveyor. The rotation of the worm conveyor causes the material situated in the outer region of the receptacle to be transported upward to the bulk material surface. This breaks up the bulk material. Material situated in the center flows downward due to the gravitational force. Consequently, a circulating motion of the bulk material takes place. The rotation of the spiral conveyor causes the broken up bulk material to be transported to the outlet opening at the receptacle bottom, at which it is discharged from the receptacle.
Patent CA-2568911-A1 (CA)
Inventor: SELLERGREN BORJE
IPC: C08F2/00
Filed: 2005-07-04
Abstract: The invention relates to a method for producing molecular imprinted polymers (MIP) which are applied as a thin film to the surface of a support material, in which a suspension of at least one functional monomer, one template and one initiator is used for the polymerisation, and with which RAFT agents are employed.
Patent CA-2568931-A1 (CA)
Title: Phase change inks containing fischer-tropsch waxes
Inventor: SNYDER TREVOR J
IPC: C09D7/12
Filed: 2006-11-23
Abstract: Disclosed is a phase change ink comprising (a) a colorant and (b) a phase change ink carrier, said carrier comprising (i) an amide and (ii) a Fischer-Tropsch wax having an average peak molecular weight of from about 300 to about 800 and a polydispersity of from about 1.001 to about 3. Also disclosed is a process which comprises (1) incorporating into an ink jet printing apparatus a phase change ink comprising (a) a colorant and (b) a phase change ink carrier, said carrier comprising (i) an amide and (ii) a Fischer--Tropsch wax having an average peak molecular weight of from about 300 to about 800 and a polydispersity of from about 1.001 to about 3; (2) melting the ink; and (3) causing droplets of the melted ink to be ejected in an imagewise pattern onto a substrate.
Patent CA-2569007-A1 (CA)
Inventor: VARKONYINE SCHLOVICSKO ERIKA
IPC: C07D409/12
Filed: 2005-04-14
Abstract: The invention relates to the crystalline and amorphous forms of the desmotrop of general formula (IB) and its salts and solvates. - where in the formula R  represents benzyl-, 2-(thienyl)methyl- or 2-(furyl)methyl group and R1 represents phenyl or furyl group substituted with C1-4 alkoxy group or halogen atom, to pharmaceutical compositions containing as for active ingredient the desmotrop of general formula (IB), and to preparation of the crystalline and amorphous forms of desmotrops (IA) and (IB).
Patent CA-2570398-A1 (CA)
Inventor: ESPINER ERIC ARNOLD
IPC: C07K16/18
Filed: 2004-06-17
Abstract: A means of measuring and monitoring skeletal growth rate using a plasma analyte, amino-terminal C-type natriuretic peptide (NT-CNP). Plasma NT-CNP  concentrations reflect the potential for further growth of the immature skeleton. Measurement of plasma NT -CNP in a subject, when related to the mean of an appropriate age and gender matched set of control subjects, provides an index of the severity of a growth disorder not otherwise available and facilitates diagnosis in children with undetected osteochondrodysplasias or other intrinsic disorders of the growth plate. The invention also provides a means of detecting and monitoring potentially harmful effects of drugs and other factors on skeletal growth long before they are evident using current methods in clinical practice.
Patent CA-2570843-A1 (CA)
Inventor: THUBERT PASCAL
IPC: H04J3/22
Filed: 2005-06-13
Abstract: An IPv4 node (18 or 20) is able to send an IPv4 packet to an IPv4 destination (22) via an IPv6 access network (14), based on translation (30 or 32) of the IPv4 packet into an IPv6 packet for transmission via the IPv6 access network (14). The IPv4 packet is translated into the IPv6 packet by a local gateway (30). The IPv6 packet has an IPv6 source address that includes a prescribed address prefix (34) assigned to the local gateway (30), and an IPv4 address of the IPv4 node (18 or 20). The IPv6 packet also includes an IPv6 destination address that includes a second address prefix (38) assigned to a remote gateway (32), and a second IPv4 adress of the IPv4 destination. The IPv6 packet is converted by the remote gateway (32) into an IPv4 packet for reception by the IPv4 destination via an IPv4 network (16).
Patent CA-2570901-A1 (CA)
Inventor: PARROTT GREG
IPC: G06F3/01
Filed: 2005-06-17
Abstract: A gaming machine having a non contact user interface and methods for receiving input to the gaming machine using the non-contact user interface are described. The gaming machine described can receive player tracking information associated with a player, where the player tracking information can include personalization information associated with the player. The gaming machine can receive a signal provided by the player at a non-contact interface device. Next, the gaming machine can decode the signal. The non-contact interface device comprises either an eye motion recognition device or a hand motion recognition device or a voice or speech recognition device or virtual keyboard or virtual touch screen. Other biometric imput means are also included, and the biometric input means are correlated with the stored tracking information.
Patent CA-2571990-A1 (CA)
Title: Ortho-substituted (3-hydroxyphenyl)-acetic acid benzylidene hydrazides
Inventor: MEDERSKI WERNER
IPC: A61P35/00
Filed: 2005-06-06
Abstract: The invention relates to the novel ortho-substituted (3-hydroxyphenyl)-acetic acid benzylidene hydrazides of formula (I), wherein R1 to R9 are defined as in claim 1. Said novel compounds are SGK inhibitors and can be used in the treatment of SGK-relates diseases and disorders such as diabetes, obesity, metabolic syndrome (dyslipidemia), systemic and pulmonary hypertension, cardiovascular diseases and renal diseases, and generally for any kind of fibroses and inflammatory processes.
Patent CA-2575254-A1 (CA)
Title: Preparation of hydrochloride salts of tetrazole derivative
Inventor: ZUPANCIC SILVO
IPC: A61P9/00
Filed: 2005-07-29
Abstract: The present invention relates to sesquihydrate hydrochloride salt of irbesartan and anhydrous hydrochloride salts of irbesartan. Irbesartan used as the starting material for the preparation of the described hydrochlorides of irbesartan can be in any form, e.g. it can be used when contained in a reaction solution, in crude form, in a filtrate containing several solvents, or in anhydrous or any solvated or hydrated form, in amorphous form or any known crystal form or in a mixture thereof.
Patent CA-2576419-A1 (CA)
Title: Enzyme inhibitor in leukemia
Inventor: TAVOR SIGAL
IPC: A61K35/55
Filed: 2005-08-04
Abstract: The invention relates to the use of an elastase inhibitor in the manufacture of a medicament for the treatment of leukemia, preferably acute leukemia and more preferably for the treatment of AML.
Patent CA-2577340-A1 (CA)
Title: Fluorescent ph detector system and related methods
Inventor: GEELHOOD STEVEN J
IPC: G01N21/64
Filed: 2005-08-19
Abstract: Fluorescent pH detector and methods for measuring pH using the fluorescent ph detector. A method and a system for measuring a sample property such as pH or carbon dioxide concentration using a probe for delivering excitation light and receiving emission light at at least two wavelengths from a fluorescent species immobilised on a substrate. The probe is physically isolated for example by a window from the fluorescent species on the substrate. The light received at the first and second wavelengths is used to determine the sample property. In addition a tip can be provided over the substrate in such a way as to permit the analyte to contact the substrate for example via a semi permeable membrane.
Patent CA-2578838-A1 (CA)
Title: Dihydropteridinone derivatives, methods for the production thereof and their use as medicaments
Inventor: SOLCA FLAVIO
IPC: C07D475/04
Filed: 2005-08-19
Abstract: The invention relates to novel dihydropteridinones of general formula (I), in which the radicals L, R1, R2, R3, R4 and R5 have the meanings cited in the claims and description, to isomers thereof, methods for producing these dihydropteridinones, and to their use as medicaments.
Patent CA-2579870-A1 (CA)
Title: Systems for managing electrical power
Inventor: FUREM KEN
IPC: H02M7/17
Filed: 2005-09-14
Abstract: Certain exemplary embodiments comprise a system comprising a plurality of Active Front End units adapted to be electrically coupled to a direct current (DC) bus. Each of the plurality of Active Front End units can be adapted to be electrically coupled to a separate winding of a transformer of a plurality of transformers. Each of the plurality of Active Front End units can be adapted to convert alternating current (AC) voltage to a DC voltage. Each of the plurality of Active Front End units can be adapted to supply the DC voltage to the DC bus. The DC bus can be adapted to be electrically coupled to a plurality of inverters
Patent CA-2586143-A1 (CA)
Title: Bristle golf mat tee
Inventor: KILLACKY IVOR ROLFE
IPC: A63B57/10
Filed: 2007-04-23
Abstract: The invention relates to a 'Bristle Golf Mat Tee' (Fig.1) for supporting a golf ball in conjunction with a golf mat normally used for either winter tees, or on a practice range. The 'Bristle Golf Mat Tee' would be interchangeable with existing tees and golf mats. The 'Bristle Golf Mat Tee' comprises of a body (1) which is made from rubber, or any other suitable moldable material, and consists of a flat circular disc attached concentrically to a tube on one end. The end of the tube not attached to the disc provides a base for a multiplicity of bristles (2). These bristles give annular support for a golf ball. The concentric tube projects up through a hole in the golf mat but terminates below the surface of the mat and provides no impediment to the golf club. The bristles project above the surface of the mat and provide support to the golf ball.  These bristles offer no resistance to the golf club and will not cause damage to the golf club or injury to the golfer in the same way that existing rubber tees, which protrude above the mat, frequently do.
Patent CA-2586624-A1 (CA)
Title: Crosslinked polymeric material with enhanced strength and process for manufacturing
Inventor: SCHROEDER DAVID W
IPC: B29C48/12
Filed: 2005-10-06
Abstract: A radiation crosslinked (50 kGy), pressure-treated UHMWPE material has been developed by applying compressive force on a crosslinked polymer in a direction orthogonal to an axial direction. The deformed material is then cooled while held in a deformed state. The resulting material is anisotropic, with enhanced strength oriented along the axial direction. The directionally engineered material is oxidatively stable even after four weeks of accelerated aging in a pressure vessel containing five atmospheres of oxygen (ASTM F2003).  Because of its oxidative stability, the deformation processed material is a suitable candidate for air-permeable packaging and gas sterilization, which has thus far been reserved for remelted highly crosslinked UHMWPEs.
Patent CA-2586765-A1 (CA)
Title: Purposeful movement of human migratory cells away from an agent source
Inventor: POTTS JOHN T JR
IPC: A61K33/243
Filed: 2005-11-04
Abstract: This invention provides methods and compositions for modulating movement of eukaryotic cells with migratory capacity. More specifically, the invention provides anti-fugetactic agents and methods for the use thereof in enhancing an immune response.
Patent CA-2588997-A1 (CA)
Title: Sensing phage-triggered ion cascade (septic)
Inventor: KISH LASZLO
IPC: C12Q1/70
Filed: 2005-11-23
Abstract: The present invention provides a method for detecting bacteria and a nano-well device having one or more input/output connections about a gap and one or more bacteriophages at or about the gap that trigger a detectable electrical field fluctuation when the one or more bacteriophages contact a cognate target within a liquid sample.