Patent EP-0379146-A3 (EP)
Title: Soft ocular lens material
IPC: C08F290/14
Filed: 1990-01-16
Abstract: A soft ocular lens material made of a copolymer 
consisting essentially of: 
   (A) from 5 to 70 parts by weight of a fluorine-­
containing (meth)acrylate;    (B) from 5 to 60 parts by weight of an alkyl 
(meth)acrylate;    (C) from 3 to 45 parts by weight of a polysiloxane 
macromonomer having polymerizable groups at both 
terminals, of the formula I: 
  
wherein each of Y¹¹ and Y¹² independently represents an 
acryloyl group, a methacryloyl group, a vinyl group or an 
allyl group; each of X¹¹ and X¹² independently represents 
a covalent bond, an oxygen atom or an alkylene glycol 
group; each of R¹¹ and R¹² independently represents a 
linear or branched alkylene group having from 1 to 6 
carbon atoms; each of R¹³, R¹⁴, R¹⁵, R¹⁶, R¹⁷ and R¹⁸ 
independently represents an alkyl group having from 1 to 
3 carbon atoms or a phenyl group; i is an integer of from 
 
 
1 to 1500; and j is an integer of from 0 to 1499 
(provided that i+j is at most 1500); and    (D) from 3 to 40 parts by weight of a polysiloxane 
macromonomer having polymerizable groups bonded via one 
or two urethane bonds to the siloxane main chain, of the 
formula II: 
  
wherein each of Y²¹ and Y²² independently represents a 
group selected from the group consisting of an 
acryloyloxy group, a methacryloyloxy group, a vinyl group 
and an allyl group; each of R³¹ and R³⁴ independently 
represents a linear or branched alkylene group having 
from 2 to 6 carbon atoms; each of X²¹ and X²² 
independently represents a covalent bond, an oxygen atom 
or an alkylene glycol group; each of R³² and R³³ 
independently represents a linear or branched alkylene 
group having from 1 to 6 carbon atoms; each of R²³, R²⁴, 
R²⁵, R²⁶, R²⁷ and R²⁸ independently represents an alkyl 
group having from 1 to 3 carbon atoms or a phenyl group; 
each of E²¹ and E²² independently represents -NHCO- 
 
 
(provided that in this case, each of X²¹ and X²² is a 
covalent bond, E²¹ forms a urethane bond together with 
X²⁵, and E²² forms a urethane bond together with X²⁶) or a 
bivalent group derived from a diisocyanate selected from 
the group consisting of saturated aliphatic, alicyclic 
and aromatic diisocyanates (provided that in this case, 
each of X²¹ and X²² independently represents an oxygen 
atom or an alkylene glycol group, E²¹ forms a urethane 
bond together With X²¹ and X²⁵, and E²² forms a urethane 
bond together with X²² and X²⁶); each of X²⁵ and X²⁶ 
independently represents an oxygen atom, an alkylene 
glycol or a group represented by the formula V: 
  
wherein R⁴¹ is a trivalent hydrocarbon group having from 
1 to 6 carbon atoms; Y²³ represents a group selected from 
the group consisting of an acryloyloxy group, a 
methacryloyloxy group, a vinyl group and a allyl group; 
R³⁶ represents a linear or branched alkylene group having 
from 2 to 6 carbon atoms; X²³ represents a covalent bond, 
an oxygen atom or an alkylene glycol group; E²³ 
represents -NHCO- (provided that in this case, X²³ is a 
covalent bond) or a bivalent group derived from a 
diisocyanate selected from the group consisting of 
saturated aliphatic, alicyclic and aromatic diisocyanates 
(provided that in this case, X²³ is an oxygen atom or an 
 
 
alkylene glycol group), which forms a urethane bond 
together with X²³ and the adjacent oxygen atom bonded to 
R⁴¹; a is an integer of from 1 to 1500; and b is an 
integer of from 0 to 1499, provided a+b ≦ 1500;    
as essential copolymer components.