baber/WOPTO huggingface dataset:
Patent HR-P20090488-T1 (HR)
Title: Process for the preparation of (3r,3as,6ar)-hexahydrofuro [2,3-b] furan-3-yl (1s,2r)-3-[[(4-aminophenyl) sulfonyl] (isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate
Inventor: GOYVAERTS NICOLAAS MARTHA FELIX
IPC: C07D493/04
Filed: 2009-09-15
Abstract: The present invention relates to a process for the preparation of (3R,3aS,6aR)­-hexahydrofuro [2,3-b] furan-3-yl (1S,2R)-3-[[(4-aminophenyl) sulfonyl] (isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate as well as intermediates for use in said process. More in particular the invention relates to processes for the preparation of (3R,3aS,6aR)-hexahydrofuro [2,3-b] furan-3-yl (1S,2R)-3-[[(4-aminophenyl) sulfonyl] (isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate which make use of 4-amino-N­ ((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-(isobutyl)benzene sulfonamide intermediate, and to processes amenable to industrial scaling up. (3R,3aS,6aR)-hexahydrofuro [2,3-b] furan-3-yl (1S,2R)-3-[[(4-aminophenyl) sulfonyl] (isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate is particularly useful as HIV protease inhibitors.
Patent HR-P20131085-T1 (HR)
Title: Use of antagonistic anti-cd40 monoclonal antibodies
Inventor: LONG LI
IPC: C07K16/28
Filed: 2013-11-13
Abstract: Methods of treating a subject for a cancer comprising neoplastic cells expressing the CD40 cell surface antigen are provided. The methods comprise combination therapy with interleukin-2 (IL-2) or biologically active variant thereof and at least one antagonist anti-CD40 antibody or antigen-binding fragment thereof. In some embodiments, these two therapeutic agents are concurrently administered as two separate pharmaceutical compositions, one containing IL-2 or biologically active variant thereof, which is administered according to a constant IL-2 dosing regimen or a two-level IL-2 dosing regimen, the other containing the antagonist anti-CD40 antibody or suitable antigen binding fragment thereof, which is administered according to a weekly dosing regimen, or alternatively is dosed once every two, three, or four weeks.; Administering of these two agents together potentiates their effectiveness in promoting a positive therapeutic response. The methods find use in treating CD40-expressing cancers, including B-cell related cancers and solid tumors.
Patent SI-1556837-T1 (SI)
Title: Method for authentication by chemical marking or tracing of an object or a substance
Inventor: LAMBERT CLAUDE
IPC: G07D7/00
Filed: 2003-10-29
Abstract: The invention concerns a method for authenticating different objects or substances to be identified comprising at least two phases: during an initial phase, selecting a plurality of chemical markers, assigning to and incorporating in each of the objects or substances a combination of markers, establishing an identification and/or authentication code (blocks 2, 11), storing in memory data or code for identifying and/or authenticating all the objects or substances and annex data; during an identification and/or authentication phase: a spectrophotometric analysis so as to determine a specific scanned code of the presence or absence of the markers (blocks 3, 4), identifying the object or the substance by comparing the scanned code and the identification and/or authentication codes (block 6). The invention is particularly applicable to fighting against counterfeiting, to automatic sorting, and the like.
Patent SI-1619143-T1 (SI)
Title: Method and device for securing the operating range of an emptying device
Inventor: DRIESBACH CHRISTIAN
IPC: F16P3/14
Filed: 2005-06-16
Abstract: The securing process secures the working region of an emptying device (10) for emptying dustbins (8) into a collecting container. The emptying device includes a lifting carriage for the dustbin. A barrier device is fitted between the collecting container and the lifting carriage, which can be moved in a movement region (S) between a rest position and a securing position.
Patent SI-1975083-T1 (SI)
Title: An insulating container
Inventor: D AMATO GIANFRANCO
IPC: B31B50/59
Filed: 2005-09-01
Abstract: The invention relates to a method of fabricating an insulating container (10) for hot drinks or the like. The container includes an inner cup (12) having a generally frusto-conical cup body (22), a generally frusto-conical outer shell (14), a thermo-sealable plastic coating (42) on at least one of the inside of said shell and the outside of said cup body. The cup is seated within said shell so that the coating extends at least along a contact path (3) near the upper edge (9) of the shell along which contact path outer surface of the cup body and inner surface of the shell are in contact and are bonded.
Patent SI-1924560-T1 (SI)
Title: 6-SUBSTITUTED- 2,3,4,5-TETRAHYDRO-1H-BENZO?áD?åAZEPINES AS 5-HT2C RECEPTOR AGONISTS
Inventor: ALLEN JOHN GORDON
IPC: A61K31/00
Filed: 2006-09-01
Abstract: The present invention provides 6-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines of Formula (I) as selective 5-HT2C receptor agonists for the treatment of 5-HT2c associated disorders including obesity, obsessive/compulsive disorder, depression, and anxiety: R6 D R?N—R″R* where R6 is —(CrC3)alkyl-S—(C0-C3)alkyl-R10, —(C1-C3)alkyl-NR11R12, —(CrC3)alkyl-O—R13. and other substituents are as defined in the specification.
Patent SI-2064532-T1 (SI)
Title: System for detecting the pressure in a vehicle tyre and/or speed of the vehicle
Inventor: PINGEL ULRICH
IPC: G01L17/00
Filed: 2007-09-13
Abstract: A system for detecting the pressure in a pneumatic vehicle tire which is mounted on a vehicle and/or the speed of the vehicle, having an arrangement composed of load sensors which supplies force signals for a two-dimensional pattern of the distribution of force which is exerted by the vehicle tire in contact with the sensors when the vehicle moves over the arrangement, a computer which is programmed in such a way that it defines the tire pressure and/or the speed on the basis of the distribution of force independently of the method of manufacture or the model of the tire and of the vehicle, and a device for displaying the pressure and/or the speed, is characterized in that the arrangement composed of load sensors comprises at least two series of load sensors which are arranged one behind the other in the direction of travel, wherein at least one row of load sensors is offset with respect to one or more rows of the load sensors by a predetermined absolute value transversely with respect to the direction of travel.
Patent SI-2102083-T1 (SI)
Title: Loading and unloading device for receptacles, such as containers, silos and other filling spaces
Inventor: HANSES CHRISTIAN
IPC: B65G53/00
Filed: 2007-01-08
Abstract: Loading and unloading device (1) has a container-trailer (5) which is arranged on exchangeable bridgework (3) that is transportable by truck. Loading and unloading device is so designed that device is mobile. The front side (6) is attached to open and close and to seal the loading or unloading box for bulk material. A telescopic pipe (16), is arranged in the loading and unloading box, comprising an associated drive unit (17) and a connection (22) for conveying bulk material, for loading into or unloading from the box. Also a suction unit with propellant air outlet and a motor-compressor unit (31) with propellant air inlet (32) for compressed air supply into the box are arranged. A vacuum cleaner, a filter and an operating-controlling unit are arranged in the box.
Patent SI-2726514-T1 (SI)
Title: Process for the preparation of 1,3-butadiene and styrene copolymers and use thereof in vulcanizable elastomeric compositions
Inventor: SODDU LUCA
IPC: C08F236/00
Filed: 2012-06-21
Abstract: A process for the preparation of a 1,3-butadiene and styrene copolymer comprising the following steps: a) anionically polymerizing a blend comprising from 5% by weight to 40% by weight of styrene and from 60% by weight to 95% by weight of 1,3-butadiene, with respect to the overall weight of the mixture, in the presence of at least one hydrocarbon solvent, of at least one lithium-based catalyst having the general formula LiR1 wherein R1 represents a linear or branched C3-C10 alkyl group, and of least one polar modifier; b) optionally, reacting the copolymer obtained in step (a) with at least one chain-end monomer selected from 1,3-butadiene, styrene and a-methylstyrene; c) reacting from 10% by weight to 70% by weight, preferably from 20% by weight to 50% by weight, of the lithium-terminated polymeric chains present in the copolymer obtained in step (a) or in step (b), with at least one coupling agent selected from liquid polyepoxides having at least three reactive sites capable of reacting with the carbon-lithium chain-ends; d) optionally, reacting the copolymer obtained in step (c) with at least one chain-end monomer selected from 1,3-butadiene, styrene and a-methylstyrene; e) reacting the linear polymeric chains remaining in the copolymer obtained in step (c) or in step (d), with at least one tin compound having the general formula XSn(R2)3 wherein X represents a halogen atom such as, for example, chlorine and R2 represents a linear or branched C1-C10 alkyl group.
Patent TR-200703263-T1 (TR)
Inventor: GUERLEK ZIHNI
IPC: F24C15/00
Filed: 2005-12-13
Abstract: The present invention relates to a cooking appliance (1) with a cooling air system having inlet (11) and outlet (12) ducts (9, 10) , a fan (8) , and a intermediate component (14) acting as baffle in oder to prevent the mixing of air inflowing to the suction duct (9) with air outflowing from the exhaust duct (10) , achieving an effective air flow.
Patent DE-3855687-T2 (DE)
Inventor: PLEWES DONALD B
IPC: H05G1/36
Filed: 1988-09-20
Granted: 1997-05-28
Abstract: A radiographic machine in which the exposure is equalized as between different areas of the image plane so as to enhance high spatial frequency features of the image and suppress low spatial frequency features and achieve other benefits as well. A fan beam (12) which is wide enough to encompass the object (16) being imaged (18) is swept across the object and segments of that beam (23) are individually pulse width modulated at each of a number of sampling intervals during the sweep by monostable or bistable shutter pins (20) which either completely block or completely uncover the sectors which they control (22). An alternate embodiment adds beam width modulation as well, by making the shutter pins either completely block their sectors or uncover them only to the degree necessary for beam width modulation.
Patent DE-3883836-T2 (DE)
Inventor: SOBEK ANDREW A
IPC: A01N25/10
Filed: 1988-05-07
Granted: 1994-01-27
Abstract: Various chemolithotrophic bacteria such as Thiobacillus ferrooxidans by direct or indirect mechanisms catalyze the oxidation of metal sulfides and produce acid, i.e. suilfuric acid and soluble metal salts at a much faster rate than chemical oxidation. Elimination of such bacteria would inhibit the formation of the acid. The natural production of such acids is particularly troublesome in mines e.g. coal mines, since acid water is produced which is damaging to the environment. An effective method of abating or eliminating such acid water production is to apply a bactericide such as a biodegradable organic surfactant which at low pH values are bactericides and hence inhibit the bacteria from catalyzing the metal sulfides. The affected acid water site can thus be treated with the surfactant which provides a temporary or short term result usually for a few months. A long term solution, that is 1 year to several years, is provided through the use of a slow release composition of the present invention in which a heterogeneous matrix contains a thermoplastic domain and an organic surfactant domain. A suitable porosity is created when proper amounts of surfactant are utilized so that a long term slow release composition is formed. A method of making the heterogeneous matrix or slow release composition involves the dry blending of a thermoplastic compound and various processing aids, subsequently adding a bactericide thereto and mixing under shear and heat the resulting molten composition. A suitable slow release article can be formed such as pellets.
Patent DE-3888120-T2 (DE)
Inventor: PANZANI IVO
IPC: A61M1/36
Filed: 1988-12-09
Granted: 1994-06-09
Abstract: An integrated unit in extracorporeal blood circuit includes a tank (1) internally provided with a wall in defoaming material (2) having at least one filter (11), adapted to delimit at least laterally a portion of space inside which blood coming from the patient and from the operating field inflows, and thus such as to act simultaneously as venous tank and as cardiotome, said tank (1) being connected monolithically to a heat exchanger (15) and to an oxygenator (14) adapted to be traversed by the outflowing blood from said tank (1).
Patent TR-199901581-T2 (TR)
Inventor: MACK ROBERT
IPC: B65D35/22
Filed: 1998-01-16
Abstract: In the manufacture of multichamber tubular containers it has been found that the inner divider walls should be bonded to the exterior wall by means of a band sealing method. In the band sealing method there is a band that contacts the upper film and a band that contacts the lower film that are to be bonded. In the present processes the upper band contacts the inner divider wall while the lower band contacts the exterior surface of the outer wall of the tubular container. In order to prevent the marring or otherwise putting a defect into the exterior surface of the outer wall the temperature of the lower band is maintained at a lower temperature than the upper band. This will decrease the temperature of the exterior surface of the outer wall and prevent imperfections in the exterior surface of the outer wall. The advantage is a multichamber tubular container without any imperfections in the exterior surface. This enhances the overall appearance of the tubular container.
Patent TR-199901934-T2 (TR)
Inventor: ANDRE JEAN-LUC
IPC: B61B13/00
Filed: 1998-02-11
Abstract: The guide system, for a guided road vehicle, having a front directional assembly formed of two pivoting guide arms (2) and (3) which are coupled as well as vertically constrained, each equipped with an inclined guide wheel (12, 13) engaging at least one guide rail on the ground (16). At the rear, a follower-limiter module (47) designed to limit lateral clearance by the axle to a maximum value, in the form of a device following the guide rail, is pivotably attached to the axle (8) and laterally displaceable to a limited extent. The front directional unit and the follower-limiter module (47) are laterally connected to either side of the axle through a lateral temporary immobilizing device (43, 44) which controls change of position.
Patent DE-60002966-T2 (DE)
Inventor: GOODWIN DAVID JOHN
IPC: F04D29/60
Filed: 2000-09-14
Granted: 2004-02-26
Abstract: A vacuum pump comprising a shaft (2) rotatable by means of a motor (3), at least two spaced pump stages (6,7) mounted on the shaft (2), a first pump inlet (11) through which gas can pass for passage through all the pump stages for evacuating a first system (20) and a second pump inlet (14) through which gas can enter the pump at an inter-stage location (8) for passage through only subsequent stages of the pump for evacuating a second system (22), said first and second systems (20,22) each having a gas outlet flange for attachment to a first or a second pump inlet, in which the vacuum pump is mounted relative to the respective first and second systems (20,22) such that the longitudinal axis of the shaft (2) is inclined to each of the gas outlet flanges.  <IMAGE>
Patent DE-60006202-T2 (DE)
Inventor: MUELLER ECKART
IPC: H02M3/158
Filed: 2000-08-28
Granted: 2004-04-15
Abstract: The invention relates to methods of operating step-up DC voltage converters including a storage choke, the one terminal of which is connected to the input of the converter and the other terminal of which is connectable via a first controllable switch to ground and via a second controllable switch to the output of the converter; a clock outputting a first clock signal dictating the switching cycle of the converter, and a second clock signal, the cycle of which corresponds to that of the first clock signal; and a regulator circuit which regulates the voltage at the output of the converter to a setpoint value. In the methods the second switch is set ON at the end of the switching cycle during a constant time duration as dictated by the second clock signal and which as compared to the length of the switching cycles is short, whilst the first switch is set OFF, so that a transient flow of energy occurs from the output of the converter to the input of the converter. Due to this, the converter is always operable at a constant frequency independent of the load and thus permits simple noise filtering of the output voltage which is particularly of advantage in telecommunication applications. The invention relates furthermore to step-up DC voltage converters for implementing the method.  <IMAGE>
Patent DE-60009561-T2 (DE)
Inventor: BUJARD PATRICE
IPC: C07D209/34
Filed: 2000-10-09
Granted: 2004-08-19
Abstract: The present application relates to a process for the manufacture of pigmented vitreous materials, as well as to pigmented vitreous materials, characterized by the use of soluble pigment precursors and preferably the absence of significant amounts of dispersants. These pigmented vitreous materials can be used as colored materials for any known purposes. Soluble pigment precursors comprising a partial structureare also claimed, wherein X1 is an aromatic or heteroaromatic ring, B is hydrogen or a group of the formulabut at least one group B is not hydrogen, and L is a solubilizing group.
Patent DE-60012595-T2 (DE)
Inventor: KANEKO SINJIRO
IPC: C21D8/02
Filed: 2000-01-25
Granted: 2004-12-16
Abstract: High tensile strength hot-rolled steel sheet suitable for use in interior materials for automobiles and a method for producing the same, in which bake hardenability, fatigue resistance, crash resistance, and resistance to room temperature aging are improved, containing 0.01% to 0.12% by weight of carbon, 2.0% by weight or less of silicon, 0.01% to 3.0% by weight of manganese, 0.2% by weight or less of phosphorus, 0.001% to 0.1% by weight of aluminum, and 0.003% to 0.02% by weight of nitrogen and subjected to hot rolling and cooling at a cooling rate of 50 DEG C/s or more within 0.5 second after hot rolling; the hot-rolled steel sheet has a structure including a ferrite having an average grain diameter of 8  mu m or less as a primary phase, the amount of solute Nitrogen ranges from 0.003% to 0.01%, and the ratio, Ngb/Ng, of an average concentration Ngb of nitrogen dissolved in the ferrite grain boundary to an average concentration Ng of nitrogen dissolved in ferrite grains ranges from 100 to 10,000. <IMAGE>
Patent DE-60013981-T2 (DE)
Inventor: JETTER ROLF
IPC: H01R13/436
Filed: 2000-07-18
Granted: 2006-02-23
Abstract: A connector for receiving terminals therein that includes a terminal block having outer side walls and opposing end walls, wherein terminal receiving passageways extend between the opposing end walls for receiving a terminal, and a primary retention member is disposed along at least one of the terminal receiving passageways that includes a resilient retention arm that extends into the passageway to retain the terminal therein, where the primary retention member is particularly adapted to situations where the spacing between the wall and the passageway is relatively small.
Patent DE-60014843-T2 (DE)
Inventor: JUDKINS REN
IPC: E06B9/78
Filed: 2000-08-08
Granted: 2006-03-09
Abstract: An operator for a window covering held on a roller or axle has a stationary member having a central cavity and a first bore sized and positioned so that the roller can pass through the bore into the central cavity. A release brake is positioned so that the axle or roller can pass through and be held by the release brake. An inertial ring within the central cavity of the stationary member, surrounds a coil spring which encircles the axle. A release member is provided adjacent the release brake and the inertial ring. The release member is sized and positioned so that when the release ring is in a first position the release member will not engage the inertial ring or the release brake and when the release member is moved in a selected direction the release member will engage and turn the release brake and the inertial ring. A spool is positioned within the central cavity of the stationary member adjacent the inertial ring. A rewind spring is connected between the spool and the stationary member such that when a force acts on the spool to turn the spool in the first direction from the initial position the rewind spring will tighten and when the force is removed the spring will loosen causing the spool to return to the initial position.
Patent DE-60017446-T2 (DE)
Inventor: GASTER LARAMIE MARY
IPC: A61K31/505
Filed: 2000-11-02
Granted: 2006-03-02
Abstract: The invention relates to novel isoquinoline and quinazoline derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of various disorders.
Patent DE-60017549-T2 (DE)
Inventor: EKHOLM HANS
IPC: A46B3/14
Filed: 2000-03-02
Granted: 2006-03-02
Abstract: A bolt (47) is made to penetrate aligned holes (45,46) drilled at a radial direction to the overlapping shoulders (35,36) of the adjoining segments (7.1,7.2). One through hole assumes a threaded state. Independent claims are also included for the following: a drum of brush roller; and an axle.
Patent DE-60025405-T2 (DE)
Inventor: ISRAEL MAURICE
IPC: A61P9/10
Filed: 2000-08-10
Granted: 2006-09-07
Abstract: Determining (D) compounds potential to modulate the release of neurotransmitters comprising contacting the compounds with a nerve tissue preparation, is new.  Independent claims are also included for the following: (1) a kit for performing (D) including nerve tissue preparations stored in separate compartments, substance(s) for reacting with released neurotransmitters and reference materials having known performance as modulators of neurotransmitter release; (2) a compound able to modulate neurotransmitter release that has been identified by (D); and (3) using (2) to make a medicament for treating diseases of the nervous system.
Patent DE-60026073-T2 (DE)
Inventor: BENTLEY DAVID
IPC: C08G65/32
Filed: 2000-12-20
Granted: 2006-09-28
Abstract: The invention provides a sterically hindered polymers and conjugates formed therefrom that comprise a water-soluble and non-peptidic polymer backbone having at least one terminus covalently bonded to an alkanoic acid or alkanoic acid derivative prior to conjugation, wherein the carbon adjacent to the carbonyl group of the acid or acid derivative group has an alkyl or aryl group pendent thereto. The steric effects of the alkyl or aryl group allow greater control of the hydrolytic stability of polymer derivatives. The polymer backbone may be poly(ethylene glycol).
Patent DE-60026972-T2 (DE)
Inventor: CHEN ZEWU
IPC: G21K1/06
Filed: 2000-01-18
Granted: 2006-12-21
Abstract: An optically curved device and method of fabrication are presented wherein a flexible layer is bonded to a thick epoxy layer which functions to conform the flexible layer to a desired shape. The thick epoxy layer undergoes high viscosity flow under pressure and conforms the flexible layer to a curved surface of a mold. The pressure on the epoxy can be created by squeezing the epoxy using a backing plate. As long as the optically smooth surface of the flexible layer has good contact with the curved surface of the mold under pressure of the epoxy flow, irregularities in the flexible layer optical surface are eliminated and the shape of the flexible layer is maintained when the epoxy is cured and the mold removed. Materials other than epoxies, such as thermal plastics can also be used for bonding and conforming the flexible layer.