baber/WOPTO huggingface dataset:
Patent DE-69519940-T2 (DE)
Inventor: LIVAK J
IPC: C12Q1/68
Filed: 1995-11-15
Granted: 2001-05-23
Abstract: There is provided:   a method for detecting a target polynucleotide in a sample comprising: contacting said sample of nucleic acids with an oligonucleotide probe under conditions favorable for hybridization; and monitoring the fluorescence of said reporter molecule, an increase in the fluorescence intensity of said reporter molecule indicating the presence of said target polynucleotide; wherein said oligonucleotide probe is an oligonucleotide probe comprising: an oligonucleotide probe which does not hybridize with itself to form a hairpin structure; a fluorescent reporter molecule attached to said oligonucleotide sequence; and a quencher molecule capable of quenching the fluorescence of said reporter molecule attached to said oligonucleotide sequence; said oligonucleotide sequence capable of existing in at least one single-stranded conformation when unhybridized where said quencher molecule is a fluorescent molecule capable of quenching the fluorescence of said reporter molecule; said oligonucleotide sequence also capable of existing in at least one conformation when hybridized to a target polynucleotide where the fluorescence of said reporter molecule is unquenched; and wherein the fluorescence intensity of said reporter molecule at its emission maximum when said oligonucleotide sequence is hybridized to said target polynucleotide is greater than the fluorescence intensity of said quencher molecule at its emission maximum when said oligonucleotide sequence is not hybridized to said target polynucleotide.   <IMAGE>
Patent DE-69521292-T2 (DE)
Inventor: BILLGREN PER
IPC: B22F8/00
Filed: 1995-01-12
Granted: 2001-10-31
Abstract: PCT No. PCT/SE95/00020 Sec. 371 Date Dec. 4, 1996 Sec. 102(e) Date Dec. 4, 1996 PCT Filed Jan. 12, 1995 PCT Pub. No. WO95/19861 PCT Pub. Date Jul. 27, 1995The invention relates to a method for the manufacturing of a composite metal product. More particularly, the invention relates to a method for the manufacturing of a composite product consisting of at least two stainless steel materials having different chemical compositions, particularly a composite stainless product on which decorative patterns can or has been produced by etching. It is significant feature of the invention that at least two stainless steel materials having different chemical compositions are bonded together through hot isostatic compaction at a pressure exceeding 600 bar and a temperature exceeding 1000 DEG  C., at least one of said materials consisting of powder, for the achievement of a consolidated body.
Patent DE-69523458-T2 (DE)
Inventor: ALAJAEAESKI TIMO
IPC: D21D5/02
Filed: 1995-06-26
Granted: 2002-04-04
Abstract: A fiber suspension, such as in a pulp mill, is treated in a manner which minimizes both the investment and the operating costs associated with a screening plant. A single pump (114) has an outlet connected to a knotter (112) and primary (120) and secondary (126) screening stages, so that the pump provides substantially the sole motive force to the pulp, moving it through the knotter and screening stages. The knotter and screening stages are provided in a common housing with the coarse screen vertically above the screening stages, and the screening stages one above the other. A single motor may be provided to rotate rotatable elements associated with the knotter and screening stages. The coarse screen may be connected to a knot washer (116) external of the housing by a valved conduit less than two meters in length, and the secondary screening stage can be connected to a tertiary screening stage (128) exterior of the housing by a valved conduit less than two meters long. Rejects from the knot washer and secondary screening stage may be recycled to the pulp inlet, and the dilution water may be introduced where necessary. <IMAGE>
Patent DE-69525427-T2 (DE)
Inventor: FERNANDO GERARD FRANKLYN
IPC: G01M11/08
Filed: 1995-11-29
Granted: 2002-09-05
Abstract: A strain monitoring device comprises an elongate radiation guide, typically an optical fibre, whose cross-section is modified in accordance with a predetermined mathematical relationship over a portion of its length at which it is emplaced in use on a material which is to be subject to strain. When energy is transmitted down the radiation guide, the output can be measured and converted to a strain value and as a result of a predeterminable correlation relationship between radiation output and such strain.
Patent DE-69526677-T2 (DE)
Inventor: TAMURA SUSAN YOSHIKO
IPC: C07F7/18
Filed: 1995-12-13
Granted: 2002-12-05
Abstract: The present invention discloses peptide aldehydes which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis.
Patent DE-69534395-T2 (DE)
Inventor: LEIDY WAYNE D
IPC: C03B7/10
Filed: 1995-10-12
Granted: 2006-08-03
Abstract: A parallel shear apparatus (10) for sequentially shearing each of a plurality of streams of molten glass (A, B, C, D) from a glass feeder into gobs for processing into glass containers by a glass forming machine. The apparatus (10) has first and second opposed carriages (12, 14) which are reciprocable along parallel slides (16, 18, 20) toward and away from one another, each of the carriages carrying one or more opposed knife elements (32a, etc., 34a, etc.), corresponding to the number of streams of molten glass, and the opposed knife elements (32a, 34a, etc.) overlap at the innermost limits of their travel to perform the shearing action. Notion of the carriages (12, 14) is actuated by a unidirectionally acting servo motor (36), which imparts oscillating motion to a bell crank (22) through a connecting rod (46). The oscillating motion of the bell crank (22) imparts simultaneous, opposed, rectilinear motion to the carriages (12, 14) through connecting rods (26, 30), which are pivotally attached to the servo motor (36) at spaced apart locations.
Patent DE-69535735-T2 (DE)
Inventor: WHITE ROBERT ASHTON
IPC: B43K8/02
Filed: 1995-12-21
Granted: 2009-04-23
Abstract: The present invention relates to an applicator for flowable materials which comprises a generally cylindrical housing having a chamber, a discharge opening, a wick projecting through said discharge opening, and a projecting structure for shielding the user from flowable materials and for preventing placement of the applicator in inappropriate receptacles. Further, the present invention relates to a storage and shipping rack for said applicators and to a method of dispensing flowable materials onto a surface. Preferably, the applicator is filled with metal coating and treating compositions such as aqueous acidic chromate compositions. Most preferably, the acidic compositions contain a very low concentration of a fluorinated surfactant.
Patent DE-69603208-T2 (DE)
Inventor: CARRUEL ANDRE
IPC: B23K9/035
Filed: 1996-01-29
Granted: 1999-11-11
Abstract: In a process for gas-shielded electric butt welding of two metal sheets (14,15) by current passage between at least one of the sheets and an electrode moved progressively along the edges (16,17) to be welded, the novelty comprises (a) placing, on the sheets prior to current passage, a flexible metal strip with two border regions coated with a heat resistant contact adhesive (pref. of cross-linked acrylic type or silicone type) for bonding onto the back faces of the sheets such that the regions extend parallel to the sheet edges (16,17); and (b) sweeping the strip middle region, between the border regions, with gas. Pref. the sheets are of stainless steel and the strip is of aluminium. Also claimed is a device for carrying out the above process and comprising a flexible metal strip coated with heat resistant contact adhesive in two border regions on one side of the strip.
Patent DE-69620001-T2 (DE)
Inventor: CHATFIELD STEVEN N
IPC: A61K39/39
Filed: 1996-11-01
Granted: 2002-11-21
Abstract: PCT No. PCT/GB96/02680 Sec. 371 Date Apr. 29, 1998 Sec. 102(e) Date Apr. 29, 1998 PCT Filed Nov. 1, 1996 PCT Pub. No. WO97/16208 PCT Pub. Date May 9, 1997The invention provides a vaccine composition in the form of a kit, comprising a first container containing an antigenic preparation comprising influenza antigen or antigens; and a second container containing an effective adjuvant amount of a chitosan which is a deacetylated chitin which is at least 80% deacetylated. The antigenic preparation in the first container preferably comprises haemagglutinin and neuraminidase influenza antigens.
Patent DE-69623823-T2 (DE)
Inventor: OSWALD A
IPC: F02F1/32
Filed: 1996-12-09
Granted: 2003-01-23
Abstract: The cylinder head assembly includes a cast member, and a substantially planar member that is affixed to an upper end of the cast member. The substantially planar member includes apertures to anchor the intake and exhaust rocker studs, apertures that receive the intake and exhaust valve, and apertures that receive the push rod guides. The substantially planar member also has spring locators for the intake and exhaust valve return springs. The cast member is affixed to the engine cylinder, and includes cast intake and exhaust manifolds, bosses for receiving the intake and exhaust valves, a cast pocket for receiving the intake and exhaust push rods, and air cooling fins. A head cover is disposed on an opposite side of the planar member. The invention eliminates the need for two cast components.
Patent DE-69632519-T2 (DE)
Inventor: FUNAKI AKIRA
IPC: B32B37/00
Filed: 1996-12-05
Granted: 2005-05-25
Abstract: A first thermoplastic resin film (25) is laid on a heated endless belt to be moved together with the endless belt (18), a second thermoplastic resin film (26) is superposed on the first thermoplastic resin film laid on the belt, and the first and second thermoplastic resin films laid on the belt are touch-rolled by a combination of the belt and a second roller (13) to be laminated. The second thermoplastic resin film can be superposed on the first thermoplastic resin film laid on the belt after being touched to the second roller. A thermally produced molding is obtained by heat trealing the laminated thermoplastic resin film (29).
Patent DE-69635186-T2 (DE)
Inventor: MEROT BERTRAND
IPC: A01H5/00
Filed: 1996-07-17
Granted: 2006-06-29
Abstract: A method for producing haemin proteins by (i) inserting into plant cells one or more nucleic acid molecules that each comprise at least one sequence coding for a protein component of an animal haemin protein capable of reversibly binding oxygen, or for a variant or portion of said protein component, and optionally a sequence coding for a selection agent; (ii) selecting cells containing nucleic acid coding for the protein component of the haemin protein; (iii) optionally propagating the transformed cells either in a culture or by regenerating whole transgenic or chimeric plants; and (iv) recovering and optionally purifying a haemin protein that includes a complex consisting of the protein or proteins coded for by said nucleic acid and at least one iron-containing porphyritic nucleus, or a plurality of such complexes.
Patent DE-69711451-T2 (DE)
Inventor: BLOMLOEF LEIF
IPC: A61K49/00
Filed: 1997-11-20
Granted: 2002-10-24
Abstract: Skin prick test for the determination of the predisposition of an individual to develop marginal periodontitis, said kit comprising: (a) a first reagent containing a known quantity of a surface structure common to anaerobic Gram negative pathogens which is capable of triggering the inflammatory response associated with periodontitis and gingivitis; (b) second reagent containing an agonist to said individual; (c) a negative control; and (d) instructions for the use of said kit; and a method for such determination of predisposition.
Patent DE-69712306-T2 (DE)
Inventor: COENEN CARL
IPC: A45B23/00
Filed: 1997-08-20
Granted: 2002-12-05
Abstract: The invention concerns a hinge between a bone (3) and crown (7) of sunshades having a diameter larger than 2.5 meters. For this purpose is used an attachment that is fastened to the bone. The notches (8) in this attachment cooperate with cams (9) of the crown (7) which form together a hinge. In the crown are notches which bear cams. The cams are on both sides flat. The pivoting parts (10) are on one side connected with the bone and on the other side foreseen with notches which cooperate with the cams of the crown. The cams on the crown and the notches in the pivoting parts form a detachable hinge. The pivoting parts have a hole (12) for the bone that reaches further than the center of the pivoting point. The arrangement is very suitable for metal or plastic die-cast.
Patent DE-69714980-T2 (DE)
Inventor: ANDRES-GIL JOSE IGNACIO
IPC: A61P9/12
Filed: 1997-04-09
Granted: 2003-04-10
Abstract: PCT No. PCT/EP97/01830 Sec. 371 Date Oct. 6, 1998 Sec. 102(e) Date Oct. 6, 1998 PCT Filed Apr. 9, 1997 PCT Pub. No. WO97/39001 PCT Pub. Date Oct. 23, 1997This invention concerns the compounds of formula (I), the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein n is zero to 6; p is zero to 3; q is zero to 3; r is zero to 3; R1 and R2 each independently are hydrogen; optionally substituted C1-6alkyl; C1-6alkylcarbonyl; trihalomethylcarbonyl; or R1 and R2 taken together with the nitrogen atom to which they are attached may form a morpholinyl ring or an optionally substituted heterocycle; each R3 and R4 independently are halo, cyano, hydroxy, trihalomethyl, trihalomethoxy, carboxyl, nitro, amino, mono- or di(C1-6alkyl)amino, C1-6alkylcarbonylamino, aminosulfonyl, mono- or di(C1-6alkyl)-aminosulfonyl, C1-6alkyl, C1-6alkyloxy, C1-6alkylcarbonyl or C1-6alkyloxycarbonyl; each R5 independently is C1-6alkyl, cyano or trihalomethyl; X is CR6R7, NR8, O, S, S(=O) or S(=O)2; each independently represents a bivalent aromatic heterocycle wherein the heterocycle may be selected from the group consisting of pyrrole, pyrrazole, imidazole, triazole, furane, thiophene, isoxazole, oxazole, isothiazole, thiazole, pyridine, pyridazine, pyrimidine, pyrazine and triazine; or one of the two bivalent aromatic heterocycles in the compounds of formula (I) may be 1,2-benzenediyl; and aryl is optionally substituted phenyl; it further relates to compositions comprising thesae compounds, as well as their use as therapeutic agents in the treatment or the prevention of CNS disorders, cardiovascular disorders or gastrointestinal disorders.
Patent DE-69715184-T2 (DE)
Inventor: BRIGGS ROBERT
IPC: C07C47/19
Filed: 1997-04-23
Granted: 2003-05-22
Abstract: This invention relates in part to processes for producing one or more substituted or unsubstituted hydroxyaldehydes, e.g., 6-hydroxyhexanals, which comprise subjecting one or more substituted or unsubstituted alkadienes, e.g., butadiene, to hydrocarbonylation in the presence of a hydrocarbonylation catalyst, e.g., a metal-organophosphorus ligand complex catalyst, and hydroformylation in the presence of a hydroformylation catalyst, e.g., a metal-organophosphorus ligand complex catalyst, to produce one or more substituted or unsubstituted hydroxyaldehydes. The substituted and unsubstituted hydroxyaldehydes produced by the processes of this invention can undergo further reaction(s) to afford desired derivatives thereof, e.g., epsilon caprolactone. This invention also relates in part to reaction mixtures containing one or more substituted or unsubstituted hydroxyaldehydes as principal product(s) of reaction.
Patent DE-69723699-T2 (DE)
Inventor: VANDEN BRANDE PIERRE
IPC: H01J37/34
Filed: 1997-10-08
Granted: 2004-06-17
Abstract: A method for the continuous etching of a substrate moving through a chamber under vacuum facing at least one counter-electrode creating a plasma in a gas to generate some radicals and/or ions able to be agitated against the surface to be etched. At least one pair of successive counter-electrodes is used in the chamber and an alternating potential is applied to these electrodes to impose a potential to these electrodes that is alternatively positive and negative with respect to the substrate. An Independent claim is also included for an installation for putting the method into service.
Patent DE-69804960-T2 (DE)
Inventor: LEMIEUX ALAIN
IPC: E01C13/08
Filed: 1998-06-09
Granted: 2002-11-21
Abstract: A synthetic turf surface for golf courses, tennis courts and other grass-surfaced game playing fields is formed of a synthetic grass carpet having a flexible base sheet (14) with closely spaced-apart upright, blade-like strands (12) of plastic material forming a dense grass-like surface. The carpet is supported upon a cushioning underpad (18) which is formed of a thick, molded sheet of open cell, expanded bead polypropylene. The resiliently compressible polypropylene underpad combined with the synthetic grass carpet closely simulates the feel of a natural grass covered playing surface.
Patent DE-69807155-T2 (DE)
Inventor: AUCLAIR GILLES
IPC: C22C38/24
Filed: 1998-06-02
Granted: 2003-05-08
Abstract: Steel for making nitride-coated springs comprises by weight 0.57-0.6% carbon, 1.5-1.6% silicon, 0.65-0.7% manganese, 0.7-0.8% chromium, 0.05-0.08% molybdenum and 0.15-0.2% vanadium, plus iron and impurities. Also claimed is a spring made from wire drawn from that steel which has a nitride surface layer over 150 mu m thick. At least the outer 20 mu m contains over 0.4% nitrogen, the layer having a superficial hardness of over 64 HRC while the hardness of the spring interior is over 50 HRC and the layer is free of white epsilon nitrides. Also claimed is the manufacture of a spring from steel wire containing 0.4-0.7% C, 1-1.7% Si, 0.4-1% Mn, 0.3-1% Cr, 0-0.2% Mo and 0-0.2% V, plus Fe and impurities. The wire is tempered at temperature (T) up to 500 degrees C and exhibits a tensile strength of at least 1990 MPa. The spring is given a nitride surface layer by heating below temperature T, and the layer contains over 0.4% N in at least its outer surface 20 mu m and is free of white epsilon nitrides.
Patent DE-69814111-T2 (DE)
Inventor: TREMOULET OLIVIER L JR
IPC: F04B53/16
Filed: 1998-09-17
Granted: 2004-03-18
Abstract: A method and apparatus for biasing a seal assembly in a high pressure fluid pump. In one embodiment, the fluid pump includes a reciprocating plunger, a seal carrier disposed about the plunger, and a seal supported by the seal carrier and sealably engaged with the plunger. The seal may be biased toward the seal carrier with a spring and may include a flange that engages the spring to restrict lateral motion of a spring relative to the reciprocating plunger. The flange may engage an inner and/or an outer surface of the spring. Where the spring is a coil spring, the flange may be continuous around the circumference of the spring or may include a plurality of spaced apart projections located around the circumference of the spring.
Patent DE-69818944-T2 (DE)
Inventor: SABLATSCHAN SIEGFRIED
IPC: B26B19/28
Filed: 1998-03-23
Granted: 2004-07-22
Abstract: In a hair-cutting apparatus (1) and in a toothed cutting device (7) for a hair-cutting apparatus (1) the toothed cutting device (7) comprises a first toothed cutter (13) and a second toothed cutter (24), which lie against one another in the area of their cuttertooth rows (18, 25) and which each have at least one supporting limb (20, 21, 46, 47) in their areas which are remote from their cutter-tooth rows (18, 25), and of which one toothed cutter (24) carries an intermediate element (48) of a low-friction material, which comprises at least one intermediate element portion (49, 50) interposed between two facing supporting limbs (20, 46, 21, 47), and furthermore it has the advantageous feature that the at least one intermediate element portion (49, 50) of the intermediate element (48) carried by the one toothed cutter (24) has a smaller dimension in the toothed cutter direction (17) than the at least one supporting limb (20, 21) of the other toothed cutter (13), which last-mentioned limb 20, 21 faces the at least one intermediate element portion (49, 50).
Patent DE-69825770-T2 (DE)
Inventor: HANNAH GARY
IPC: A62B18/08
Filed: 1998-09-11
Granted: 2005-08-25
Abstract: Inflatable harness respiratory apparatus (10) is provided having an improved comfort control assembly (16) allowing reduction in the engagement force exerted by the fitting surface (20) of the mask (12) against the face of the user. The mask (12) is equipped with an inflatable harness strap element (26) having terminal ends (28, 30) supported on stationary, tubular mask mounts (36) via housing assemblies (38). In one embodiment, the terminal ends (28, 30) are releasably locked onto the mounts (36) by means of locks (52), but are axially shiftable along the length of the mounts (36) in order to adjust the effective distance between the fitting surface (20) and the terminal ends (28, 30). An adjustment button (78) may be depressed in order to disengage the locks (52) and permit shifting of the associated terminal end (28, 30). Alternately, an intermediate comfort position is pneumatically achieved by controlled pressurization of an internal cavity (128) within the housing assembly (88).
Patent DE-69828977-T2 (DE)
Inventor: SCHMITT J
IPC: A61F2/06
Filed: 1998-09-03
Granted: 2005-07-07
Abstract: An implantable textile prosthesis includes a first woven section having a tubular branch wall defining a fluid passageway therethrough. The tubular branch wall includes an elongate tubular extent and an asymptotically flared tubular extent, which is asymptotic with respect to the tubular branch wall. The asymptotically flared tubular extent includes a weaving pattern having a plurality of warp yarns and fill yarns and incorporating a gradual change in the number of warp yarns with respect to the fill yarns to provide a seamless and substantially fluid-tight transition region along said flared tubular extent. The tubular branch wall may be sutured to an elongate tubular main wall to provide an implantable tubular textile prosthesis particularly useful in branched end-to-side anastomoses. The tubular main wall may be heat-settably arched to resemble the natural arch of the aorta.
Patent DE-69836730-T2 (DE)
Inventor: WILKINS WILLIAM
IPC: G21K7/00
Filed: 1998-04-08
Granted: 2007-10-04
Abstract: PCT No. PCT/AU98/00237 Sec. 371 Date Apr. 8, 1999 Sec. 102(e) Date Apr. 8, 1999 PCT Filed Apr. 8, 1998 PCT Pub. No. WO98/45853 PCT Pub. Date Oct. 15, 1998A sample cell for use in x-ray imaging, including structure defining a chamber for a sample and, mounted to the structure, a body of a substance excitable by an appropriate incident beam to generate x-ray radiation, the cell being arranged so that, in use, at least a portion of the x-ray radiation traverses the chamber to irradiate the sample therein and thereafter exits the structure for detection.
Patent DE-69904263-T2 (DE)
Inventor: BONAITI MARCO
IPC: F16B45/02
Filed: 1999-07-05
Granted: 2003-09-04
Abstract: A connector with snap closure comprises a pair of levers (3, 3') elastically stressed, each lever (3, 3') having a formed end (8, 8') for performing the closure for the connector (1), and the other formed end (9, 9'; 10, 10') for providing a snap element and an element for manual control of opening of the connector (1). <IMAGE>
Patent DE-69904519-T2 (DE)
Inventor: ESCRIBANO ANA MARIA
IPC: C07D277/12
Filed: 1999-02-23
Granted: 2003-07-10
Abstract: The present application provides novel sulphonamide derivatives of formulae I, XVII in which the variables are defined as in the claims, which are useful for potentiating glutamate receptor function in a mammal requiring treatment, processes and intermediates for their preparation, and pharmaceutical compositions containing them. <CHEM>