baber/WOPTO huggingface dataset:
Patent WO-2021163625-A1 (WO)
Title: Methods for intracellular barcoding and spatial barcoding
Inventor: CHEN ZHOUTAO
IPC: C12Q1/6837
Filed: 2021-02-12
Abstract: The present disclosure provides methods for high throughput barcoding nucleic acids and/or protein inside the cells. The in-cell single cell capture method uses an individual cell itself as a compartment and delivers a plurality of unique identifiers, e.g., barcodes into the cell and captures the nucleic acid and/or protein targets within the cell directly. It significantly simplifies single cell analysis experimental setup and eliminates the need of external compartment generation. It provides a high throughput single cell expression profiling and cellular protein quantitation method, and targeted sequencing with in-cell capture will be able to significantly increase sensitivity and specificity for low frequent mutation detection, such as, somatic mutation in very early stage of cancer and truly enables early cancer detection. A spatial expression and/or variation detection method for a tissue sample is developed with the combination of the in-cell barcoding method and positional barcode on a planar array.
Patent WO-2021167876-A1 (WO)
Inventor: KATNANI HUSAM
IPC: G06Q50/22
Filed: 2021-02-16
Abstract: La présente invention concerne un système informatique de prise en charge de recherche illustratif qui conserve des données de sujet représentant des attributs pour des sujets de recherche inclus dans un groupe de sujets potentiels pour des études potentielles de recherche. Le système reçoit, d'un dispositif client, un ensemble de données d'entrée représentant : 1) un ensemble de paramètres définissant une étude de recherche à mener par rapport à un groupe de sujets de recherche, et 2) un ensemble de critères pour des sujets de recherche qui doivent être inclus dans le groupe de sujets de recherche. Le système désigne un sujet de recherche inclus dans le groupe de sujets potentiels pour une inclusion dans le groupe de sujets de recherche sur la base de l'ensemble de critères et reçoit des données de recherche détectées pour le sujet de recherche en fonction de l'ensemble de paramètres. Le système fournit également un ensemble de données de sortie généré sur la base des données de recherche détectées pour le sujet de recherche en fonction de l'ensemble de paramètres. La présente invention porte également sur des procédés et sur des systèmes correspondants.
Patent WO-2021178135-A1 (WO)
Inventor: TITONE RYAN S
IPC: A61F2/24
Filed: 2021-02-17
Abstract: Systems and methods for cutting tissue using a transcatheter approach are disclosed. In some examples, the systems and methods are implemented as part of a delivery system that includes an implant with a support structure and a cutting element coupled to the support structure, such that the cutting element configured to cut tissue.
Patent WO-2021173584-A1 (WO)
Title: Ensemble de gestion de la douleur multimédicamenteux
Inventor: LOSKOVE JOSEPH
IPC: A61K31/197
Filed: 2021-02-23
Abstract: La présente invention concerne un ensemble de gestion de la douleur multimédicamenteux pour distribuer au moins deux médicaments pour traiter la douleur comprenant un n-polygone primaire, et un ou plusieurs m-polygones concentriques, chaque côté du n-polygone et des m-polygones ayant au moins n ou m chambres de médicament aptes à contenir les au moins deux médicaments. La présente invention concerne également un ensemble de gestion de la douleur multimédicamenteux comprenant un disque, le disque étant divisé en régions équidistantes, et chaque région ayant des chambres capables de contenir des médicaments. La présente invention concerne également des formulations uniques pour traiter la douleur.
Patent WO-2021178934-A1 (WO)
Inventor: THOMAS BRIAN
IPC: C12N15/113
Filed: 2021-03-06
Abstract: Described herein are methods, compositions, and systems derived from uncultivated microorganisms useful for gene editing.
Patent WO-2021216209-A1 (WO)
Inventor: DELFOSSE NICOLAS
IPC: G06N10/00
Filed: 2021-03-09
Abstract: A quantum computing system is adapted to prepare a cat state in a quantum circuit with fault tolerance t and circuit depth less than or equal to 4+4 t  by performing a series of operations that includes: performing a sequence of joint parity measurements on individual pairs of neighboring qubits in a series of qubits entangled to form an initial cat state; repeating the sequence of measurements over at least t-rounds; and disentangling a first set of alternating qubits from the initial cat state, the prepared cat state being formed by a remaining second set of alternating qubits, the second set of alternating qubits being interlaced with the first set of alternating qubits along a line of one-dimensional connectivity, the series of operations being sufficient to guarantee that a prepared cat state is has less than or equal to t number of faults.
Patent WO-2021183767-A1 (WO)
Title: Methods for reflector film growth
Inventor: LI LUPING
IPC: C23C16/06
Filed: 2021-03-11
Abstract: Methods and apparatus for forming reflector films are described A liner is formed on a substrate surface followed by formation of the reflector layer so that there is no oxygen exposure between liner and reflector layer formation. In some embodiments, a high aspect ratio structure is filled with a reflector material by partially filling the structure with the reflector material while growth is inhibited at a top portion of the structure, reactivating the top portion of the substrate and then filling the structure with the reflector material.
Patent WO-2021202728-A1 (WO)
Title: Collectible with themed design and content
Inventor: BOUCARD JOHN
IPC: G06F1/02
Filed: 2021-03-31
Abstract: A collectible is provided. The collectible includes a viewer operable to display content. The viewer has a body which at least partially encapsulates a processor and a display. The body forms a recess which is operable to at least partially receive a remote. The remote is operable to control the viewer. When the remote is at least partially received within the viewer, the remote and the viewer together form a design which corresponds to a theme. The content displayed by the viewer also corresponds to the theme. The display has a size that is smaller than 2 inches.
Patent WO-2021207603-A1 (WO)
Title: Modular tool container
Inventor: BURNS COURTNEY J
IPC: B25H3/02
Filed: 2021-04-09
Abstract: A tool case including a base having a lower surface and a tool holder insert supported by the base. The lower surface of the base defines a plurality of guides. The tool holder insert includes a base portion, an insert portion extending from the base portion in a first direction, a main body portion extending from the base portion in a second direction that is opposite the first direction, and a wing extending outwardly from the base portion. The insert portion engages one of the plurality of guides. The main body portion is configured to receive an oscillating multi tool blade, and the wing has a detent that engages another of the plurality of guides.
Patent WO-2021211582-A1 (WO)
Inventor: VAN ZYL GIDEON
IPC: H01J37/32
Filed: 2021-04-13
Abstract: Sont divulgués des réseaux d'impédance d'entrée et des procédés associés. Un réseau d'impédance d'entrée comprend une paire de bornes sources configurée pour se coupler à une source d'alimentation, une paire de bornes à énergie récupérée configurée pour se coupler à un réservoir de puissance, une ligne de transmission couplée à la paire de bornes sources qui comprend M sections, et N circuits de calage. Chacun des N circuits de calage est configuré pour caler au moins une tension ou un courant dans l'une des M sections, et un circuit de récupération d'énergie est couplé aux N circuits de calage pour permettre à l'énergie récupérée d'être appliquée à la paire de bornes à énergie récupérée.
Patent WO-2021216517-A1 (WO)
Inventor: RADTKE TIMOTHY J
IPC: B25B27/00
Filed: 2021-04-20
Abstract: Systems and methods for determining a status of an action performed by a power tool. For example, the power tool includes a power tool housing, an accessory, and an electronic processor. The housing includes a recess and an input device. The accessory is configured to be received by the recess. The accessory includes an identifier. The electronic processor is connected to the input device. The electronic processor is configured to receive a first signal from the identifier, determine an accessory type based on the first signal, receive a second signal from the input device, initiate an action based on the second signal, determine an outer diameter of the workpiece, calculate a force applied by the power tool, determine a distance traveled by the accessory during the action, and determine a status of the action based on the force applied to the workpiece and the distance.
Patent WO-2021216854-A1 (WO)
Inventor: HOKE JOLENE
IPC: A23K10/30
Filed: 2021-04-22
Abstract: Long lasting edible pet chews are disclosed with a composition comprising protein, fiber and starch where the protein and fiber are crude protein and fiber. The composition is substantially digestible by an animals digestive system. Processes of producing such pet chews are further disclosed including a method for production involving die extrusion.
Patent WO-2021222855-A1 (WO)
Inventor: SHARMA SUNIL
IPC: A61K39/00
Filed: 2021-04-30
Abstract: The present invention provides a method for educating and expanding tumor infiltrating lymphocytes (TILs) into a therapeutic population of TILs for adoptive cell immunotherapy. Also provided are methods of treating cancer patients with the therapeutic population of TILs.
Patent WO-2021226244-A1 (WO)
Title: Vasoactive intestinal peptide fusion proteins for the treatment of covid-19
Inventor: LEE JOHN
IPC: A61K31/443
Filed: 2021-05-05
Abstract: The present disclosure provides methods of treating inflammatory lung conditions such as COVID-19 with a fusion protein comprising a vasoactive intestinal peptide (VIP) and an elastin-like peptide.
Patent WO-2022240388-A1 (WO)
Title: Ensembles et procédés de décharge de pression
Inventor: PRYMULA DAVID
IPC: B65D51/16
Filed: 2021-05-10
Abstract: L'invention concerne une fermeture (20) pour un contenant sous pression ayant une plaque avec un côté supérieur (24) et un côté inférieur (28), une première encoche (22) qui s'étend autour d'un premier axe (A1) le long du côté supérieur, et une seconde encoche (26) qui s'étend autour du premier axe le long du côté inférieur. Les première et seconde encoches forment une membrane (62) qui est apte à être rompue lorsqu'une pression maximale amène la membrane à se rompre.
Patent WO-2021236472-A1 (WO)
Title: System, method, and computer program product for providing quick response (qr) codes for injection systems
Inventor: MURPHY STEVEN
IPC: A61M5/20
Filed: 2021-05-17
Abstract: A system for providing a quick response (QR) code associated with an injection system is disclosed. The system includes the injection system and at least one processor. The at least one processor is programmed or configured to: receive data associated with the injection system; generate a network resource based on the data associated with the injection system, wherein, when generating the network resource, the at least one processor is programmed or configured to encode the data associated with the injection system into the network resource; generate a QR code based on the network resource; and display the QR code on a display screen of the injection system.
Patent WO-2021242588-A1 (WO)
Title: Group identification and monitoring
Inventor: SIEMER JAMES
IPC: G06K9/00
Filed: 2021-05-19
Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for group identification and monitoring. The methods, systems, and apparatus include actions of determining, using one or more first frames of a video sequence, that two people each of whom is depicted in at least one of the first frames satisfy a grouping criteria that indicates that the two people should be grouped for video analysis, determining, using one or more second frames of the video sequence at least some of which were captured after the one or more first frames and which depict at least one of the two people, that the two people satisfy a degrouping criteria that indicates that the two people should not be grouped for video analysis, determining that a physical distance between the two people violates a distance criteria, and providing an alert that the distance criteria is violated.
Patent WO-2021252182-A1 (WO)
Title: Methods for laser processing coated substrates using a top-hat energy distribution
Inventor: HOEHM SANDRA
IPC: B23K26/53
Filed: 2021-05-26
Abstract: A method of separating a coated substrate includes directing an infrared laser beam onto a first surface of the coated substrate. The coated substrate includes a coating layer disposed on a transparent workpiece, a plurality of defects is disposed within the coated substrate along a contour line that divides a primary region from a dummy region of the coated substrate from a dummy region of the coated substrate. The method also includes translating at least one of the coated substrate and the infrared laser beam relative to each other such that an infrared beam spot traces an oscillating pathway that follows an offset line in a translation direction and oscillates between an inner and outer track line, the oscillating pathway is disposed on the dummy region of the coated substrate, and the infrared laser beam applies thermal energy to the plurality of defects to induce separation of the coated substrate.
Patent WO-2021243003-A1 (WO)
Title: Plant antimicrobial compositions and methods of use thereof
Inventor: MANDADI KRANTHI
IPC: A01P1/00
Filed: 2021-05-27
Abstract: Applicants have developed novel methods and compositions for treating, preventing or ameliorating the effects plant phytopathogen infestation in plants, including of  Candidatus  Liberibacter spp. the causal agents of citrus greening and potato zebrachip disease. Novel compositions include one or more active agents of aminocaproic acid, carbinoxamine maleate, chloroxylenol, chlorpropamide, cinoxacin, duartin, and cyclopentolate hydrochloride as well as their derivatives, or salt/acid forms thereof. Methods of preventing disease development and infestation by plant pathogens are disclosed as well as methods of making, using and producing such compositions.
Patent WO-2021243270-A1 (WO)
Title: Devices, systems, and methods for facilitating tissue delivery of drug
Inventor: BHAMLA MOHAMMED SAAD
IPC: A61N1/30
Filed: 2021-05-28
Abstract: Devices and methods are provided for administering a drug to a biological tissue in a patient, such as by intracellular and/or dermal delivery. The device includes a piezoelectric pulse generator; and an array of microneedle electrodes electrically coupled to the piezoelectric pulse generator, wherein the device, following insertion of the microneedle electrodes into the biological tissue, is configured to generate and deliver one or more electrical pulses through the microneedle electrodes effective to electroporate cells in the biological tissue and enable delivery of a drug into the electroporated cells.
Patent WO-2021247592-A1 (WO)
Inventor: GUPTA AWNISH
IPC: C23C16/40
Filed: 2021-06-01
Abstract: Various embodiments herein relate to methods and apparatus for depositing silicon oxide using thermal ALD or thermal CVD. In one aspect of the disclosed embodiments, a method for depositing silicon oxide is provided, the method including: (a) receiving the substrate in a reaction chamber; (b) introducing a first flow of a first reactant into the reaction chamber and exposing the substrate to the first reactant, where the first reactant includes a silicon-containing reactant; (c) introducing a second flow of a second reactant into the reaction chamber to cause a reaction between the first reactant and the second reactant, (i) where the second reactant includes hydrogen (H2) and an oxygen-containing reactant, (ii) where the reaction deposits silicon oxide on the substrate, and (iii) where the reaction is initiated when a pressure in the reaction chamber is greater than 10 Torr and equal to or less than about 40 Torr.
Patent WO-2021252467-A1 (WO)
Title: Modular meal system
Inventor: KNEZOVICH LAUREN
IPC: B65B3/00
Filed: 2021-06-08
Abstract: An example modular meal system includes two or more modular meal components. Example modular meal components include a tray, a meal component disposed within the tray, and a sauce component disposed within the tray. The meal component is selected from a protein component, a starch component, a vegetable component, an appetizer component, and a dessert component. Each modular meal component is configured and/or formulated to reach at least 165F or at least 167F when heated from frozen for a heating time period within the range of from about 20 minutes to about 60 minutes and at a heating temperature within the range of about 350F to about 450F.
Patent WO-2023282920-A1 (WO)
Inventor: BROWN DONN JASON
IPC: E21B43/38
Filed: 2021-07-20
Abstract: A downhole gas separator assembly. The gas separator comprises a drive shaft; a first fluid mover mechanically coupled to the drive shaft having a fluid inlet and a fluid outlet; a fluid reservoir concentrically disposed around the drive shaft and located downstream of the first fluid mover, wherein an inside surface of the fluid reservoir and an outside surface of the drive shaft define a first annulus that is fluidically coupled to the fluid outlet of the first fluid mover; a second fluid mover having a fluid inlet and a fluid outlet, wherein the second fluid mover is located downstream of the fluid reservoir, and wherein the fluid inlet of the second fluid mover is fluidically coupled to the first annulus; and a gas flow path and liquid flow path separator having a gas phase discharge port open to an exterior of the assembly and a liquid phase discharge port.
Patent WO-2022035844-A1 (WO)
Title: Companion diagnostic for axitinib
Inventor: SWIECICKI PAUL
IPC: A61K31/00
Filed: 2021-08-10
Abstract: The disclosure provides methods for treating cancer with axitinib by first selecting a subject for treatment that has a mutation in one or more genes involved in the phosphoinositide 3-kinase (PI3K) signaling pathway followed by administering a dose of axitinib to the selected subject.
Patent WO-2022047270-A1 (WO)
Inventor: Martich Jasmine
IPC: A61K8/41
Filed: 2021-08-28
Abstract: The disclosure relates to buffer systems having ammonium hydroxide, ammonium bicarbonate, and optionally monoethanolamine, hair color bases, hair color altering compositions, and kits and methods for altering the color of hair. Hair color bases and hair color altering compositions comprise a buffer system having ammonium hydroxide, ammonium bicarbonate, and optionally monoethanolamine.
Patent WO-2022066800-A1 (WO)
Title: Velocity control-based robotic system
Inventor: SUN ZHOUWEN
IPC: B25J5/00
Filed: 2021-09-22
Abstract: A velocity control-based robotic system is disclosed. In various embodiments, sensor data is received from one or more sensors deployed in a physical space in which a robot is located. A processor is used to determine based at least in part on the sensor data an at least partly velocity-based trajectory along which to move an element comprising the robot. A command to implement the velocity-based trajectory is sent to the robot.
Patent WO-2022076435-A1 (WO)
Title: Pharmaceutical composition of siglec-binding agents
Inventor: WU BIN
IPC: A61P37/00
Filed: 2021-10-05
Abstract: This invention provides a pharmaceutical composition comprising an agent that can bind Siglec receptors on cell surface. This invention also provides the method of preparing said pharmaceutical composition and the use thereof.
Patent WO-2022081408-A1 (WO)
Title: Procédés, systèmes et dispositifs de stockage, de chiffrement et de remplacement de données
Inventor: PAREKH SANJAY
IPC: G06F11/30
Filed: 2021-10-07
Abstract: Système configuré pour : accepter un champ de données provenant d'un service d'appel, d'une application ou d'un utilisateur ; et générer un champ de données de remplacement ou un jeton destiné à être utilisé par l'appelant au lieu du champ de données réel.
Patent WO-2022082053-A1 (WO)
Title: Estimation de mouvement améliorée pour inter-codage
Inventor: XIU XIAOYU
IPC: H04N19/513
Filed: 2021-10-15
Abstract: L'invention concerne des procédés, des appareils et des supports de stockage non transitoires lisibles par ordinateur permettant de coder un signal vidéo. Un décodeur peut obtenir un premier vecteur de mouvement (MV) associé à un bloc vidéo dans le signal vidéo. Le décodeur peut obtenir un premier signal de prédiction du bloc vidéo à l'aide du premier MV. Le décodeur peut identifier un MV optimal par l'application d'un algorithme d'affinement de mouvement basé sur un gradient d'une manière récursive à l'aide du premier signal de prédiction et du premier MV. Le décodeur peut obtenir un second signal de prédiction du bloc vidéo sur la base du MV optimal.
Patent WO-2022103996-A1 (WO)
Title: Compositions d'argile et procédés d'amélioration des performances d'un animal
Inventor: FRIESEN KIM
IPC: A61K35/02
Filed: 2021-11-11
Abstract: Des compositions d'additifs alimentaires et des procédés d'utilisation des additifs pour améliorer les performances d'un animal adulte sont divulgués. Les performances améliorées peuvent comprendre la réduction des besoins nutritifs d'entretien, l'amélioration des performances de croissance, la réduction de l'énergie requise pour l'entretien intestinal, la réduction de l'énergie requise pour le gain de poids, la réduction de la morbidité, l'augmentation du taux de croissance, l'amélioration de l'indice de consommation, l'amélioration du gain quotidien moyen (ADG), l'amélioration de l'efficacité de l'utilisation des éléments nutritifs, l'augmentation de la production d'acides gras volatils, l'amélioration de la consommation d'énergie à partir d'acides gras volatils, l'augmentation du poids corporel final, l'amélioration de la santé intestinale, l'augmentation de l'abondance relative de Bifidobacterium dans les intestins, ou des combinaisons de ces performances.
Patent WO-2022125577-A1 (WO)
Title: Système de prédiction d'ajustement de déplacement
Inventor: HULTGREN BRUCE
IPC: A61C5/77
Filed: 2021-12-07
Abstract: Système de développement d'un plan de traitement dentaire comprenant un générateur de plan de traitement dentaire qui compare des mesures de mâchoire de base à un ensemble de données de taille et de mouvement de mâchoire humaine. Le système comprend un modèle paramétrique de mouvement de mâchoire divisé en segments représentatifs qui peuvent être comparés à une mesure de la mâchoire d'un patient pour générer un plan de traitement dentaire qui réduit l'interférence et la nécessité d'un ajustement pendant le déroulement du traitement.
Patent WO-2022147201-A1 (WO)
Title: Systèmes et procédés pour l'extraction d'ions à partir d'un flux de gaz
Inventor: ROEHR NATHAN
IPC: C08L23/04
Filed: 2021-12-30
Abstract: L'invention concerne des systèmes pour l'extraction d'ions à partir d'un flux de gaz, comprenant un boîtier, un trajet de manipulation d'ions et une pompe. Le boîtier comprend des orifices d'entrée, de sortie et de pompe à vide. L'orifice d'entrée est conçu pour recevoir un flux de gaz comprenant des ions et du gaz. Le trajet de manipulation d'ions comprend des première et seconde surfaces ayant respectivement des première et seconde pluralités d'électrodes et est positionné à l'intérieur du boîtier et conçu pour recevoir le mélange de gaz, extraire des ions à partir de celui-ci et transférer les ions extraits vers l'orifice de sortie. La pompe est conçue pour extraire le gaz par l'orifice de pompe à vide. L'invention concerne également des procédés pour l'extraction d'ions à partir d'un flux de gaz, comprenant l'extraction d'ions à partir d'un flux de gaz contenant des ions et du gaz à l'aide d'un trajet de manipulation d'ions, le transfert des ions extraits vers un orifice de sortie d'un boîtier à l'aide du trajet de manipulation d'ions et l'extraction du gaz à partir du boîtier par un orifice de pompe à vide.