baber/WOPTO huggingface dataset:
Patent DE-69629202-T2 (DE)
Inventor: MITCHELL M
IPC: A61P31/00
Filed: 1996-10-17
Granted: 2004-04-22
Abstract: The invention provides a method of inducing a mucosal immune response in a subject, comprising administering to the subject an amount of antigen-encoding DNA effective to induce a mucosal immune response complexed to a transfection-facilitating cationic lipid and an amount of vitamin D3. In the method of inducing a mucosal immune response, the antigen-encoding DNA can encode an antigen that is expressed on the surface of transfected cells and mimic critical elements of infection. DNA encoding the envelope glycoproteins of viral pathogens is used in the present method. Cationic lipids are bifunctional molecules consisting of one or more hydrophobic chains covalently linked to a cationic grouping in which there is coordination of positively charged groups with a negatively charged phosphate oxygen of the DNA chain forming an ionic charge complex. Two preferred examples of cationic lipids are DOGS (dioctadecylamidoglycylspermidine) and TEDBI (N,N,N',N'-tetramethyl N,N'-bis(2-hydroxyethyl)-2,3-dioleoyloxy-1,4-butanediammonium iodide). The invention also provides a composition, comprising an amount of DNA encoding an envelope antigen or envelope-associated antigen of a pathogen complexed to a cationic lipid. More specifically, the invention provides a composition, comprising an amount of DNA encoding an envelope antigen of HIV complexed to a cationic lipid.
Patent DE-69631329-T2 (DE)
Inventor: NAMIKI MITSUO
IPC: A61K38/18
Filed: 1996-03-07
Granted: 2004-11-18
Abstract: This invention relates to a PEG-modified HGF (Hepatocyte Growth Factor), namely HGF modified by polyethylene glycol. The PEG-modified HGF of the invention has a prolonged clearance in vivo, effectively exhibits its physiological activity for a long period of time, and has the same physiological activity as HGF, which makes it possible to reduce the dose and relieve the side effects of the same.
Patent DE-69631690-T2 (DE)
Inventor: HEMMINGS ARTHUR
IPC: C12Q1/42
Filed: 1996-11-05
Granted: 2005-01-13
Abstract: There is provided a process for activating a kinase of a signalling pathway comprising treatment thereof with a phosphatase inhibitor. Moreover, we describe methods for screening candidate immunosuppressive and antiproliferative agents using thus activated kinases.
Patent DE-69634454-T2 (DE)
Inventor: NAUGHTON K
IPC: A61L27/36
Filed: 1996-06-06
Granted: 2006-05-11
Abstract: The present invention is directed to methods for producing naturally secreted human extracellular matrix material and compositions containing the extracellular matrix material. The method includes culturing extracellular matrix-secreting human stromal cells on a biocompatible three-dimensional framework in vitro. After secretion of the extracellular matrix onto the framework, the stromal cells are killed and the cells and cellular contents are removed from the framework. The extracellular matrix material deposited on the framework is collected and further processed to obtain a physiologically acceptable compositions. The compositions of the present invention are useful for the repair of soft tissue and skin defects, including wrinkles and scars.
Patent DE-69636390-T2 (DE)
Inventor: BURKOTH L
IPC: A61K31/5517
Filed: 1996-05-30
Granted: 2007-09-20
Abstract: Compositions, devices, and methods for transdermal administration of an active agent are disclosed using a novel dual permeation enhancer mixture comprising lauryl acetate and a monoglyceride, preferably glycerol monolaurate. The dual permeation enhancer mixture comprising lauryl acetate is a potent permeation enhancer and provides stable systems which are more readily characterized.
Patent DE-69710051-T2 (DE)
Inventor: ZAVAREH SHAHRIARI
IPC: C07D211/34
Filed: 1997-03-07
Granted: 2002-08-14
Abstract: A process for preparing substantially single enantiomer d-threo-methylphenidate, proceeds by means of a classical salt resolution using (-)-menthoxyacetic acid.
Patent DE-69712292-T2 (DE)
Inventor: BLACKBURN BRIAN K
IPC: B60R22/12
Filed: 1997-11-13
Granted: 2002-12-05
Abstract: A seat belt buckle (12) includes a latch mechanism (20) and a field effect device (26). The latch mechanism (20) includes a latch (42) which is movable into and out of a locking position in which it engages a seat belt tongue (16) to interlock the tongue (16) with the latch mechanism (20). The field effect device (26) provides a first output if the seat belt tongue (16) is not interlocked with the latch mechanism (20) and provides a second, different output if the seat belt tongue (16) is interlocked with the latch mechanism (20). <IMAGE>
Patent DE-69726720-T2 (DE)
Inventor: CATES D
IPC: G01R33/28
Filed: 1997-03-27
Granted: 2004-10-28
Abstract: A method for hyperpolarizing  129 Xe, comprising: 
hyperpolarizing  129 Xe in a target gas, characterised in that said gas comprises: 
a) a fluorescence-quenching gas, for quenching alkali-metal fluorescence, 
b) a buffer gas, for pressure-broadening the optical absorption spectrum of alkali metal atoms, and 
c) xenon comprising  129 Xe in at least isotopic abundance; 
under conditions sufficient to induce hyperpolarization of said  129 Xe by spin exchange with alkali metal atoms, thereby providing hyperpolarized  129 Xe.
Patent DE-69728600-T2 (DE)
Inventor: SPEER DREW VE
IPC: B32B27/08
Filed: 1997-02-18
Granted: 2005-04-14
Abstract: A package for oxygen sensitive goods is made using a barrier material, an oxygen scavenging system, and a polymeric base which is reactive with the by-products of oxygen scavenging. Such packages demonstrate improved product quality.
Patent DE-69731151-T2 (DE)
Inventor: KURIBAYASHI TAKESHI
IPC: H05K13/04
Filed: 1997-01-23
Granted: 2006-02-23
Abstract: PCT No. PCT/JP97/00139 Sec. 371 Date Sep. 19, 1997 Sec. 102(e) Date Sep. 19, 1997 PCT Filed Jan. 23, 1997 PCT Pub. No. WO97/27522 PCT Pub. Date Jul. 31, 1997A method for forming mounting data, includes reading component text data corresponding to to-be-mounted components of individual mounting positions stored in a component electronic catalog, according to mounting-position data including mounting angles relating to the mounting positions formed on the to-be-mounted components, by using the component electronic catalog that has stored image data concerning various types of components including the to-be-mounted components as well as component text data necessary for component mounting including configurations and dimensions of the components. The method also includes forming mounting data for a mounter to receive components and mount them to specified mounting positions according to the mounting-position data as well as the component text data read for the individual mounting components concerning the to-be-mounted components corresponding to the mounting-position data.
Patent DE-69735580-T2 (DE)
Inventor: LUDEVID DOLORES
IPC: C07K14/00
Filed: 1997-01-28
Granted: 2007-02-01
Abstract: An oligonucleotide including at least one concatenation coding for a polypeptide of formula (P-K)<SUB>n</SUB>, wherein n is an integer of at least 2, P is a proline amino acid residue, K is a lysine amino acid residue, and the sign "-" is a bond, particularly a peptide bond, between the two amino acid residues. The n (P-K) units are also bound together by such bonds, e.g. peptide bonds.
Patent DE-69735963-T2 (DE)
Inventor: ASGHARIAN BAHRAM
IPC: A61K31/13
Filed: 1997-11-17
Granted: 2007-01-25
Abstract: The use of low molecular weight amino alcohols in ophthalmic compositions is described. These compounds have been found to enhance the efficacy of anti-microbial preservatives.
Patent DE-69737497-T2 (DE)
Inventor: DURBAN JACK
IPC: B60B33/00
Filed: 1997-04-09
Granted: 2007-11-29
Abstract: An anti-theft vehicle system for a vehicle wheel having a rotational axis includes at least one inhibitor disposed within the vehicle wheel to selectively engage and disengage the vehicle wheel to resist and allow rotational movement of the vehicle wheel about its rotational axis. The anti-theft vehicle system also includes rotatable structure disposed within the vehicle wheel and cooperating with the at least one inhibitor for moving the at least one inhibitor between an engaged position and a disengaged position with respect to the vehicle wheel. The anti-theft vehicle system further includes a receiver operatively associated with the vehicle wheel to receive a predetermined signal to activate the rotatable structure to move the at least one inhibitor between the engaged position and disengaged position.
Patent DE-69801441-T2 (DE)
Inventor: MATHIEU BRUNO
IPC: G11B33/04
Filed: 1998-06-15
Granted: 2002-05-02
Abstract: The invention concerns a support base (1), in particular for compact disc (5), comprising means for fixing a compact disc (5) by its central aperture and at least a supporting zone (2, 3) to be in contact with part of the compact disc (5), characterised in that: the support base has a cutout defining a single arm (6) capable of elastic deformation under a force of pressure (P) directed towards said support base (1); the arm (6) free end (7) has a push-button (8) made in a single piece; the push-button comprises fixing means combined with centring means (12 or 14); under said force of pressure (P), the push-button (8) passes beneath the compact disc (5) plane, to clear its central aperture; after said force is released, the elastic arm (6) returns to its initial position raising the disc.
Patent DE-69802004-T2 (DE)
Inventor: HEINZ JR
IPC: H01M50/193
Filed: 1998-11-12
Granted: 2002-05-29
Abstract: A miniature galvanic cell employing a cup-insulating member-current collector assembly, preferably a plastic insulating member and low surface area current collector, to prevent or minimize the formation of gases, such as hydrogen, on the current collector member. A process for producing such a cell is also disclosed.
Patent DE-69812601-T2 (DE)
Inventor: GERDIL CATHERINE
IPC: C12Q1/06
Filed: 1998-04-03
Granted: 2003-10-09
Abstract: The invention concerns a method for determining, in a composition containing different species of types of live viruses, the amount of viruses of each type or species, consisting in the following steps: propagating viruses of each type or species on cells permissive to the viruses but not inducing viral interference, assaying each type or species of virus using a specific monoclonal antibody.
Patent DE-69822409-T2 (DE)
Inventor: FRANC MAXIME
IPC: A23L27/40
Filed: 1998-12-02
Granted: 2005-10-27
Abstract: Common salt, combined with a vegetable additive powder which has a low specified heterogeneity index, is new. Sodium chloride salt has a vegetable additive powder content with a heterogeneity index of less than 25 (preferably 2-6) %, the heterogeneity index being the absolute value of the mathematical equation (1/a) x (a-(b+c/2)) x 100 (I), where a, b and c are the respective vegetable additive contents in the median, upper and lower zones of a salt sample subjected to a standard vibration test. An Independent claim is also included for a method of manufacturing salt containing a vegetable additive by mixing moist sodium chloride salt of greater than 20 (preferably 25-50) g/kg moisture content with the vegetable additive powder and then drying to less than 20 (preferably ≤ 10) g/kg moisture content. Preferred Features: The values a, b and c have relative differences of less than 20 (preferably 0.8-12) %, the relative differences being defined by the absolute values of (a-b)/a, (a-c)/a and (b-c)/a. The sodium chloride powder is of 200-600 mu  particle size (Tyler) and the vegetable additive powder is of  NOTGREATER  100 mu  particle size (Tyler).
Patent DE-69825678-T2 (DE)
Inventor: ALVAREZ BERENGLIER ANTONIO
IPC: A01K1/015
Filed: 1998-06-19
Granted: 2005-08-25
Abstract: A new composition which is absorbent and inhibitive of the formation of bad smells in absorbent hygienic litter for animals that comprises a carrier and a molecular complex is described. The carrier is a porous, granular, solid, clayish, mineral substrate with a high specific surface, with a high liquid absorption capacity. The molecular complex is a mixture of natural and/or synthetic organic compounds, some identical to natural ones, with properties inhibitive of bad smells, caused by the products of bacterial degradation of cat urine, by means of specific reactions of neutralization thereof. The molecular complex is basically retained inside the structure of the particles of the carrier, in such a way that the inhibitive activity thereof is regulated and strengthened by the physicochemical properties of the carrier. Preferably, the molecular complex is present in the composition in a conclentration of 0.02 to 2% of the total weight thereof. <IMAGE>
Patent DE-69828784-T2 (DE)
Inventor: VERSTEEG FREDERIK
IPC: B01D53/50
Filed: 1998-05-29
Granted: 2006-04-06
Abstract: The invention relates to a method for selectively removing sulphur and/or sulphur containing contaminant compounds from a gas flow, which also comprises CO2, said method comprising the steps of: placing the gas flow into contact with a preselected metal ion at a pH lying in the range of between about -0.05 and about 7.0, wherein the metal ion and the contaminants react together in order to form a solid metal salt of the contaminants which precipitates out of the gas flow, wherein the lower pH limit of about -0.05 substantially ensures that the metal salt formed between the metal ion and the contaminants substantially exclusively is precipitated out of the gas flow, and wherein the upper pH limit substantially ensures that CO2 is not precipitated out of the gas flow as a metal carbonate salt.
Patent DE-69834024-T2 (DE)
Inventor: GOLUB M
IPC: A61K31/00
Filed: 1998-01-15
Granted: 2006-12-07
Abstract: The invention is a method of inhibiting cancer growth, by inhibiting cellular proliferation, invasiveness, or metastasis, or by inducing cytotoxicity against cancer in mammals. The method employs 6-demethyl-6-deoxy-4-de(dimethylamino)tetracycline (CMT-3) and other functionally related chemically modified, preferably non-antibacterial, tetracycline compounds to inhibit cancer growth. The method is particularly effective to inhibit the establishment, growth, and metastasis of solid tumors, such as tumors derived from colon cancer cells, breast cancer cells, melanoma cells, prostatic carcinoma cells, or lung cancer cells.
Patent DE-69904627-T2 (DE)
Inventor: THOMSON WALTER
IPC: A47L5/30
Filed: 1999-10-04
Granted: 2003-10-02
Abstract: A changeover valve comprises a first valve member and a second valve member. The first value member has an aperture. The second valve member has first and second apertures. The first valve member is movable relative to the second valve member for selective alignment of the first value member aperture with one or other of the apertures of the second valve member. The value also has a ramp and follower means for automatically moving the valve member away from the one another during changeover movement of the first valve member relative to the second valve member so that wear on the surfaces of the valve members is minimized.
Patent DE-69917557-T2 (DE)
Inventor: GARCIA FERNANDO
IPC: H02K19/10
Filed: 1999-10-06
Granted: 2005-07-14
Abstract: A subsyncronous reluctance electrical machine comprises a stator 10 provided with a core comprised of an assembly of magnetically uncoupled or weakly coupled sectors 11 of ferromagnetic plates having longitudinal teeth 1 arranged on the face thereof turned towards the rotor 20 and provided with grooves 2 to house a winding 6. This winding 6 is comprised of a plurality of coils surrounding each sector 11 of the ferromagnetic material of stator 10 in a properly distributed manner, so as to generate a magnetic field whenever this winding is energized. The sub-synchronous reluctance electrical machine possesses as an integral part thereof said rotor 20 which in turn is provided with a core of magnetic plates having longitudinal teeth 21 uniformly arranged along the face thereof turned towards the stator 10, said teeth 21 being in a number different from the number of teeth 1 of stator 10. The machine is further provided with a monitoring device 4, for relative identification of the teeth of rotor 20 and stator 10, in order to allow the achievement of a maximum torque. <IMAGE>
Patent DE-69923675-T2 (DE)
Inventor: TAPOLSKY GILLES H
IPC: A61P31/04
Filed: 1999-04-29
Granted: 2006-05-11
Abstract: The present invention relates to a pharmaceutical delivery device for application of a pharmaceutical to mucosal surfaces. The device comprises an adhesive layer and a non-adhesive backing layer, and the pharmaceutical may be provided in either or both layers. Upon application, the device adheres to the mucosal surface, providing localized drug delivery and protection to the treatment site. The kinetics of erodability are easily adjusted by varying the number of layers and/or the components.
Patent DE-69928469-T2 (DE)
Inventor: MILLOY GORDON THOMAS
IPC: E21B33/072
Filed: 1999-05-19
Granted: 2006-08-03
Abstract: A pressure control apparatus is described, particularly for use with wireline pressure equipment (30), as having a first portion (50), which may be located in close proximity to the wireline pressure equipment. The first portion has at least one fluid pressure outlet and at least one controlling mechanism to facilitate control of the fluid pressure outlet. The controlling mechanism is operable by a control system (52), at least a portion of which is located remote from the first portion in, for instance a control cabin. A method of controlling pressure equipment used in the exploration, production and/or exploitation of hydrocarbons is also described, as is a regulating device. <IMAGE>
Patent DE-69929115-T2 (DE)
Inventor: HAHN DIETER
IPC: B60J10/74
Filed: 1999-06-10
Granted: 2006-08-03
Abstract: Automobile window glass includes a peripheral zone that cooperates at least in places with a sealing element (4). The surface of the glass (1), at least in the peripheral zone of contact with the sealing element (4), is provided with a structuring element (2) in order to establish a large number of locally limited contact surfaces between the sealing element and the glass (1). The structuring element (2) is made of sintered ceramic that is preferably transparent, and is obtained from a material applied by serigraphy. The element (2) comprises a number of points (3) or a line structure.
Patent DE-69930515-T2 (DE)
Inventor: KELLENBERGER LAURENZ
IPC: C12N9/10
Filed: 1999-07-06
Granted: 2006-12-14
Abstract: Nucleic acid molecules encoding at least part of a Type I polyketide synthase, and having a polylinker with multiple restriction enzyme sites in place of one or more PKS genes encoding enzymes associated with reduction, optionally further including nucleic acid incorporated into the polylinker, the further nucleic acid encoding one or more reductive enzymes; plasmids incorporating such nucleic acids; host cells transfected with such plasmids; methods relating thereto.
Patent DE-69934579-T2 (DE)
Inventor: LEVIN SHALOM
IPC: A01D34/73
Filed: 1999-03-11
Granted: 2007-10-25
Abstract: A self adjusting suspension system for a blade housing. The riding cushions (3) make contact with the ground along surface. When the housing (2) is at its lowest point, a nut (10) comes in contact with a stopper (14) and thereby prevents the housing (2) from coming down any further. By rotating the nut (10) left or right against a screw (13), which is a continuation of rod (11), the lowest point of the housing (2) can be controlled.
Patent DE-69934674-T2 (DE)
Inventor: LOGOTHETIS J
IPC: H01L23/498
Filed: 1999-02-11
Granted: 2007-10-18
Abstract: A platform is provided for the manufacture of microwave, multilayer integrated circuits and microwave, multifunction modules. The manufacturing process involves bonding fluoropolymer composite substrates into a multilayer structure using fusion bonding. The bonded multilayers, with embedded semiconductor devices, etched resistors and circuit patterns, and plated via holes form a self-contained surface mount module. Film bonding, or fusion bonding if possible, may be used to cover embedded semiconductor devices, including embedded active semiconductor devices, with one or more layers.
Patent DE-69936600-T2 (DE)
Inventor: LAMBERT ANDRE
IPC: B29C45/00
Filed: 1999-09-14
Granted: 2008-04-17
Abstract: The process involves injecting into mold a composition comprising thermoplastic matrix in form of thermoplastic polymer A, reinforcing filler in form of fibrous substance B with factor L/D above 20, fine filler C with form factor L/D below 20, and nucleation agent D. Substance B is selected from glass, ceramic, carbon and thermoplastic polymer fibers, while C is selected from mineral fillers such as glass spheres, ground glass, glass scales or their mixtures. The process involves injecting into mold a composition comprising thermoplastic matrix in form of thermoplastic polymer A, reinforcing filler in form of fibrous substance B with factor L/D above 20, fine filler C with form factor L/D below 20, and nucleation agent D. Substance B is selected from glass, ceramic, carbon and thermoplastic polymer fibers, while C is selected from mineral fillers such as glass spheres, ground glass, glass scales or their mixtures. Thermoplastic composition preferably contains 10-60 wt.% of total B + C fillers and wt. ratio of C to B is 0.2-10. The content of D is preferably below 1 wt.% per total wt. of composition. The composition may also contain additives such as pigments, colorants, thermo- and/or photo-stabilizers, and durability modifiers.
Patent TR-200003142-T2 (TR)
Title: Yeni oktahidro-6,10-diokso-6H-piridazino [1,2-A] [1,2] diazepin-1-karboksilik asit türevleri.
Inventor: COLLADANT COLETTE
IPC: C07K5/06
Filed: 1999-04-26
Abstract: Bulus, R'nin bir hidrojen atomunu, 18'e kadar karbon atomunu içeren bir alkil ya da aralkil radikalini temsil ettigi, amin ödevli grubunun serbest halde ya da korunmus halde oldugu SR konfigürasyonundaki ya da SR + SS karisim seklindeki formül (I)'in bilesikleri ile ilgilidir. Bilesikler, ilaçlar için aktif maddelerin hazirlanmasi için kullanilabilir.
Patent TR-200103128-T2 (TR)
Title: Proton pompasì nleyicileri veya H2 reseptr antagoistleri ile kombinasyon halinde (-) norcisaprid kullanìlan metodlar ve terkipler
Inventor: RUBIN PAUL D
IPC: A61K31/445
Filed: 2000-03-01
Abstract: Buluç, mideyle ilgili baG rasaklarla ilgili rahats zl klar n engellenmesine, tedavi edilmesine, ya da idare edilmesine mahsus bileçiklere ve bunlar n kullan m na iliçkin olup, 5-HT3 al c lar n n, 5-HT4 al c lar n n, ve H2 al c lar n n ve proton pompalar n n en az ndan birbirinin üzerinde bir üçlü sahal  eti saGlamak üzere bir ya da daha fazla maddeden ya da bileçikten faydalanmaktad r.
Patent TR-200103705-T2 (TR)
Title: Üstten doldurma izabe ocağı için yükleme tertibatı
Inventor: IRNICH FRANZ JOSEF
IPC: C21B7/20
Filed: 2000-06-23
Abstract: Bir birinci, epey yatay durumdaki dönem ekseni (A1) etrafinda rotasyonlu tahrikli, bir birinci tahrik (119)'lu ve ana gövdenin çikisina (107a) sabitlenmis ve onunla döndürülebilen bir yükleme kizagi (111)'li silindirik bir ana gövde (107)'li bir dönme kizagi (107;111)'e sahip, üstten doldurmali bir izabe ocagi (101)'in yüklenmesine yarayan bir yükleme tertibati (100) olup, yükleme kizagi ana gövdenin çikisina bitisik üst kisimla (113) birinci dönme eksenine yönelmis uzunlamasina mesafe ve üst kisimla döndürülebilecek sekilde bagli, birinci dönme eksenine uzak önemli ölçüde yatay ikinci bir dönme eksenine uzak önemli ölçüde yatay ikinci  bir dönme ekseni (A2) etrafinda dönmek için ikinci bir tahrik (127)'ye sahip bir alt kisim (115)'den olusmaktadir.
Patent TR-200201628-T2 (TR)
Title: Bir kompresörde piston konumunun kontrol edilmesi ve izlenmesi için yöntem
Inventor: SCHWARZ MARCOS GUILHERME
IPC: F04B49/10
Filed: 2000-12-22
Abstract: Bir kompresörün kontrol edilmesi için bir yöntem, özellikle, pistonun, kompresör içinde temin edilmis süpap sistemine karsi çarpmasini engelleyen bir yöntem anlatilmistir. Bu bulusun amaci, pistonun sübap sistemine çarpmasina izin vermeden, uç yük kosullari altinda pistonun mekanik hamlesinin ucuna kadar ilerlemesine olanak saglayarak, bir dogrusal kompresörün pistonunun hamlesinin kontrol edilmesidir.