baber/WOPTO huggingface dataset:
Patent IL-199497-A0 (IL)
Title: Polypeptide conjugate comprising human factor vii or human factor viia like molecules, nucleotide sequence encoding therefor, method for production thereof, and uses thereof
IPC: A61K38/00
Filed: 2009-06-23
Abstract: The present application relates to factor VII (FVII) or Factor VIIa (FVIIa) polypeptide conjugates, to their preparation and use in therapy, in particular for the treatment of a variety of coagulation-related disorders. These polypeptide conjugates comprise at least one non-polypeptide moiety covalently attached to a polypeptide, wherein the amino acid sequence of the polypeptide differs from that of wild-type FVII or FVIIa in that at least one amino acid residue comprising an attachment group for said non-polypeptide moiety has been introduced or removed. The conjugates of the present application have one or more improved properties as compared to commercially available rFVIIa, including increased functional in vivo half-life and/or increased plasma half-life, and/or increased bioavailability and/or reduced sensitivity to proteolytic degradation.
Patent IL-202206-A0 (IL)
Title: Substituted (oxazolidinon-5-yl-methyl) -2-thiophene-carboxamides and use thereof in the field of blood coagulation
Filed: 2009-11-18
Abstract: The invention relates to novel substituted oxazolidinones, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of thromboembolic disorders.
Patent IL-210478-A0 (IL)
Title: Steroidal c-17 benzimidazoles in crystalline forms and a method for their preparation
Filed: 2011-01-06
Abstract: Described are steroidal C-17 benzoazoles, pyrimidinoazoles (azabenzoazoles) and diazines. Methods for their synthesis are also described, which include methods having a step of nucleophilic vinylic "addition-elimination" substitution reaction of 3²-acetoxy-17-chloro-16-formylandrosta-5,16-diene or analogs thereof and benzoazole or pyrimidinoazole nucleophiles and methods having a palladium catalyzed cross-coupling reaction of 17-iodoandrosta-5,16-dien-3²-ol or analogs thereof with tributylstannyl diazines. The compounds are potent inhibitors of human CYP 17 enzyme as well as potent antagonists of both wild type and mutant androgen receptors (AR). The compounds are useful for the treatment of human prostate cancer.
Patent RO-200800096-A0 (RO)
Inventor: EPUREANU ALEXANDRU
Filed: 2008-02-04
Abstract: The invention relates to a method and an equipment intended for volume nanostructuring blanks as bars or wires of low diameter and high lengths, by severe plastic deformation. According to the invention, the method consists in achieving a uniform nanostructuring while highly refining the crystalline grains of a material, the plastic deformation taking place in one or more sections of a blank, by shearing perpendicular to the blank axis, upon continuously changing direction and at continuously changing deformation size and rate, along a programmed trajectory, associated with the severe axial compression of the blank and the permanent change of the shearing section, as a consequence of the repeated axial motion of the blank at a certain advance rate, up to the complete nanostructuration thereof on its entire length. The claimed equipment comprises a blank (1) in contact with some half-bushings (2', 2'', 18' and 18'') and some bushings (9 and 14), integral with a slide (10) performing a motion (c) normal to the blank axis and another slide (11), integral with another bushing (12), simultaneously performing a motion (d) normal to the motion (c) and to the axis of the blank (1), both motions taking place with the view of material shearing in one or more sections thereof and being so programmed as to result in the deformation trajectory (T), the repeated axial motion of the blank (1) with the advance (s) being achieved by means of two hydraulic cylinders (5 and 15) made integral with the blank (1) by two respective pairs of half bushings (2', 2'') and (18', 18'') and which, under the action of the oil existing in some chambers (a) and (b), generate forces to compress the blank (1).
Patent RO-125511-A0 (RO)
Title: Composite material with electro-catalytic properties based on polytyramine and platinum and process for obtaining the same
Inventor: SPĂTARU NICOLAE
IPC: B01J23/42
Filed: 2009-12-14
Abstract: The invention relates to a composite material used as electro-catalyst for combustion cell and to a process for obtaining the same. According to the invention, the material consists of a polytyramine matrix on which there are deposited platinum particles, having a specific active surface of 30...60 mp/g. According to the invention, the process consists in depositing, by cyclic voltammetry, some films of polytyramine on the surface of some graphite electrodes there resulting a polymer matrix, afterwards there is carried out the electro-chemical deposition of some platinum particles into the matrix pores, by applying a cathodic potential, wherefrom there results a composite material which is stabilized by cyclic voltammetry in the potential range -0.2...1.2 V.
Patent RO-132662-A0 (RO)
Title: Nitrocarburizing process, in particular sulphonitrocarburizing process
Inventor: COJOCARU MIHAI OVIDIU
IPC: C23C8/48
Filed: 2018-02-22
Abstract: The invention relates to a process for enriching the superficial layers of metal pieces made of alloyed or highly alloyed steel for tools, with nitrogen and carbon by nitrocarburizing or with nitrogen, carbon and sulphur by sulphonitrocarburizing, in order to improve the mechanical wear-resistance of the superficial layer and the sticking resistance, by lowering the friction coefficient. According to the invention, the process consists in using a thermochemical treatment at a temperature of minimum 350°C in nitrogen-, carbon- and/or sulphur- donor solid powdery medium, the solid powdery medium consisting of 50% carbamide in admixture with 48...45% active carbon, used as carbamide dissipating/dispersing medium upon its fusion at 133°C, as a storage medium and as a reagent, with 2% ammonium chloride as activator and/or 3% sulphur, the metal pieces arranged in metal boxes for thermochemical treatment being heated in oven at a temperature ranging between 350...590°C, maintained at the same thermal plateau for 3....24 h, depending on the layer thickness, phase composition and modified properties desired to be obtained.
Patent MC-2101-A1 (MC)
Inventor: RUTENBERG MARK R
IPC: G01N15/14
Filed: 1989-03-24
Abstract: An automated screening system and method for cytological specimen classification in which a neural network is utilized in performance of the classification function. Also included is an automated microscope and associated image processing circuitry.
Patent MC-2397-A1 (MC)
Inventor: SEKI IKUYA
IPC: C07K16/30
Filed: 1995-11-28
Abstract: A peptide having affinity with tumor or a salt thereof, which comprises an amino acid sequence containing 20 or less amino acid residues, said amino acid sequence being described as X1-YCAREPPT-X2 wherein A, C, E, P, R, T and Y represent amino acid residues expressed by standard one-letter symbols, each of amino acid residues A, C, R and Y in the amino acid sequence YCAR may be in either L-form or D-form, X1 represents a basic organic compound having 1-3 amino groups, and X2 represents any given amino acid sequence, is provided together with a radioactive diagnostic agent and a radioactive therapeutic agent containing the above peptide or a salt thereof. The present tumor affinity peptide is high in radioactive metal labeling yield, useful for imaging and treating pathological tissues such as of breast cancer, ovarian cancer and colon cancer of mammals including human, and difficult to be readily metabolized in organisms and to accumulate in normal tissues especially at kidney and liver. <MATH>
Patent LU-85738-A1 (LU)
Inventor: ULVELING LEON
IPC: C21B5/00
Filed: 1985-01-24
Abstract: 1. Process for the injection of metered quantities of pulverulent materials by pneumatic means and at a plurality of different points into an enclosure which is under variable pressure, through pneumatic channels fed with pulverulent material and propulsion fluid under pressure supplied by a booster, characterized in that in each transport track an intermediate deposit of pulverulent material is provided in a proportioning hopper into which the pulverulent material is introduced at pressure P1 , in that the pulverulent material is extracted by means of a current of gas at a pressure P2 lower than P1 , in that the pressure difference DELTA p = P1 - P2 is continuously measured and in that the pressure P2 is set at a level which ensures that the pressure difference DELTA p will correspond to a certain quantity of pulverulent material transported per unit of time by the carrier gas at a pressure P2 .
Patent MA-22744-A1 (MA)
Inventor: BG CONROY
IPC: E01B9/48
Filed: 1992-12-16
Abstract: PCT No. PCT/GB92/02359 Sec. 371 Date Aug. 11, 1994 Sec. 102(e) Date Aug. 11, 1994 PCT Filed Dec. 18, 1992 PCT Pub. No. W093/12296 PCT Pub. Date Jun. 24, 1994.A railway rail fastening clip (1) suitable for holding down a railway rail (2) is formed from a rod of resilient material bent so as to be approximately M-shaped in plan, the clip (1) being such that, when it is bearing on the flange of a rail (2), the longitudinal axis of a part (14) thereof, which interconnects inner legs (13, 15) of the M, lies in a reference plane which is substantially parallel, but not identical, to a plane containing the longitudinal axes of outer legs (11, 17) of the M. Such clips (1) are used with an anchoring device (5), which, as the clip (1) is installed therein, deflects the outer legs (11, 17) downwardly with respect to the inner legs (13, 15), so as to place the clip under stress.
Patent MA-37420-A1 (MA)
Inventor: ABDELLATIF BENABDELLAH
IPC: A45B11/00
Filed: 2014-10-10
Abstract: Un pare-soleil frontal ergonomique de véhicule permettant de mouvements simples de manipulation. Un support fixé au toit est relié à un bras amovible grâce à une rotule sphérique. Le bras est attache au pare-soleil grâce à une glissière insérée dans une coulisse du pare-soleil.
Patent MA-37686-A1 (MA)
Title: Composés phénoxyéthyl pipéridine
Inventor: SCHIFFLER MATTHEW ALLEN
IPC: C07D211/60
Filed: 2013-06-20
Abstract: La présente invention concerne un composé de la formule ii : formule ii dans laquelle x représente : r
Patent MA-38470-A1 (MA)
Title: Prédiction et optimisation du traitement phytosanitaire par micro-ondes des matériaux et des emballages
Inventor: KADDAMI HAMID
IPC: A61L2/12
Filed: 2015-10-09
Abstract: Cette invention concerne une méthode de calcul et de modélisation qui permet de prévoir la distribution et le profile de température dans les matériaux d'emballage et par conséquent elle propose d'optimiser le temps nécessaire pour leur traitement phytosanitaire. En effet, le chauffage microondes est un processus complexe qui implique des interactions hautement non linéaires entre les caractéristiques physicochimiques et mécaniques du matériau traité (propriétés mécaniques, thermiques et électriques). Cela pose un défi de taille pour la simulation numérique parce que les complexités combinées de la chaleur et du transfert de masse, du changement de phase et thermomécanique et interactions électromagnétiques doivent être considérés. D'autre part, le bois et les autres matériaux utilisés pour l'emballage pourrait être très hygroscopique, sont très souvent structurellement anisotrope et présentent une mauvaise conductivité thermique. En outre, ils présentent aussi des propriétés diélectriques anisotropes qui varient en fonction de la teneur en humidité, la température, la fréquence et l'orientation des champs électriques, fournissant des indices pou prédire avec précision la distribution de chaleur et d'optimiser le temps de traitement phytosanitaire. L'invention comprend un procédé de calcul et un logiciel qui permet de contrôler la distribution de la chaleur, d'optimiser et de prédire avec précision le temps requis pour le traitement phytosanitaire utilisant un chauffage par micro-ondes. Cela est applicable pour touts les bois et les matériaux d'emballage (bois, polymères, composites, papier et autres matériaux utilisés pour l'emballage).
Patent UY-26524-A1 (UY)
Title: Procedimiento para la preparación de esteres ácidos aril-iminometil-carbámicos.
Inventor: HAMM RAINER
IPC: C07C271/00
Filed: 2001-01-08
Abstract: El invento se refiere a un procedimiento aplicable a gran escala técnica para la preparación de compuestos de la fórmula (I) en la que los radicales R1 y R2 pueden tener los significados mencionados en la memoria descriptiva y en las reivindicaciones.
Patent UY-27547-A1 (UY)
Title: Método para la identificación de enzimas marcadores tumorales
Inventor: SHIMMA NOBUO
IPC: A61K/
Filed: 2002-11-22
Abstract: La presente invención se refiere a un método para la identificación de enzimas que se expresan preferencialmente en ciertos tejidos tumorales en comparación con tejidos o células normales de crecimiento rápido, la utilización de tales enzimas para el diseno del compuesto para generar una sustancia anticancerígena basados en dichas enzimas, sus sales farmacéuticamente aceptables así como la composición farmacéutica de las mismas.
Patent ZW-15687-A1 (ZW)
Title: Method and apparatus for biological processing of metal-containing ores
Inventor: ROBERT CLARENCE EMMETT
IPC: C22B3/00
Filed: 1987-08-17
Abstract: A method and attendant apparatus for use in bioleach processing of metal-bearing solids is disclosed. The method includes the placement into a tank of metal-bearing solids, a predetermined quantity of water, oxygen, carbon dioxide, nutrients and a species of microorganisms capable of oxidizing some portion of the metal-bearing solids and obtaining energy for growth from that oxidation. The slurry formed by this placement is continuously filtered to remove process delimiting metabolic end products products by the oxidation reaction. The ratios of the various slurry components are monitored and controlled to effectuate an optimized environment for oxidation to occur. The attendant apparatus includes a means of introducing oxygen into the bottom of the reactor vessel in the form of small widely dispersed bubbles.
Patent AT-518351-A1 (AT)
Title: Biogasanlage
Inventor: DR RICHARD MOOSBRUGGER
IPC: C12M1/00
Filed: 2016-02-01
Abstract: Biogasanlage (1) zur Herstellung von Biogas, wobei die Biogasanlage (1) zumindest einen thermophil betriebenen Fermenter (2) und außerhalb des Fermenters (2) zumindest eine Anreicherungsvorrichtung zum Anreichern eines Bakterienanteils in einem aus dem Fermenter (2) entnommenem Substrat und zumindest eine erste Transportvorrichtung (3) zum Transport des aus dem Fermenter (2} entnommenen Substrats in die Anreicherungsvorrichtung und zumindest eine zweite Transportvorrichtung (4) zum Transport des in der Anreicherungsvorrichtung angereicherten Substrats zurück in den Fermenter (2) aufweist, wobei die Anreicherungsvorrichtung eine Eindampfvorrichtung zum Eindampfen des Substrats ist.
Patent ES-148748-A1 (ES)
Title: PERFECCIONAMIENTOS EN LOS INHALADORES AUTOMáTICOS DE OXiGENO PARA VUELOS A GRANDES ALTURAS
IPC: A62B7/14
Filed: 1939-10-31
Abstract: Perfeccionamientos en los inhaladores automáticos de oxígeno para vuelos a grandes alturascaracterizados por comprender un dispositivo de distribuciónuna válvula de reducción de presiónun manómetroun regulador automático de corriente y un indicador de la corriente de oxígenoen el cual el regulador automático de corriente es controlado por una cápsula barométrica mediante una palanca provista de un casquete elástico deformableadaptado para impedir el escape de oxígeno al exterior del aparato.
Patent ES-179099-A1 (ES)
Title: Un procedimiento de regular la temperatura del vapor
Filed: 1947-07-26
Abstract: Un procedimiento de regular la temperatura del vapor de un recalentador que recibe su calor principalmente por convección desde gases que dejan una salida en la parte superior de un horno vertical cuyas paredes están forrada de tubos refrigerados por agua; caracterizado porque se introducen combustible y aire en la parte inferior del horno desde una pluralidad de puntos apartados de la salida del horno con preferencia cerca del fondo del mismo en direcciones tales que crean una masa de gas turbulento que arde en una zona de la parte inferior del horno para transmitir calor a los tubos de agua del mismo; mantener para una carga dada una velocidad virtualmente uniforme de quema de combustible y alterar el ángulo con la horizontal de la dirección de las corrientes de combustible y aire para bajar o levantar la situación vertical de la zona de combustión a lo largo del eje del horno conforme aumenta y disminuye respectivamente la temperatura del vapor recalentado para alterar así la longitud del trayecto de gas en el horno y la medida en que los gases se enfría antes de llegar al recalentador.
Patent ES-180580-A1 (ES)
Title: UN NUEVO SISTEMA DE FIJACIoN PARA ESQUi
Filed: 1947-11-07
Abstract: Nuevo sistema de fijación para esqui caracterizado por el hecho de que la base de la mordaza está dispuesta de tal forma que pueda girar sobre al plano horizontal del esquí al sobrepasar una determinada resistencia y desplazarse transversalmente a la dirección longitudinal del esquí.
Patent ES-189548-A1 (ES)
Title: UN TRANSPORTADOR ELEVADOR DE PAJA UTILIZABLE COMO COMPLEMENTO DE LAS MáQUINAS TRILLADORAS
Filed: 1949-08-27
Abstract: Un transportador-elevador de paja utilizable como complemento en las máquinas trilladoras esencialmente constituido por un bastidor de planta rectangular con medios de sustentación y desplazamiento con unos montantes en su parte delantera para la sustentación de unas ruedas-guía y un canal basculante por el que pasa la rama de actuación del elemento sinfin o transportador propiamente dicho con medios para su accionamiento caracterizada por el hecho de que el referido canal está formado por dos tramos de igual sección articulados entre sí de manera que independientemente del cambio de posición angular que puede experimentar el referido canal cuando se utiliza la máquina puede el mismo formar un ángulo para que su tramo delantero quede levantado con el fin de acortar en esta forma la longitud de la propia máquina.
Patent ES-193038-A1 (ES)
Title: Un sistema perfeccionado de banderilla
Filed: 1950-05-19
Abstract: Un sistema perfecionado de bandrilla caracterizada por la formación de dos vastagos de madera unidos por encaje a un tubo metalico uno de ellos portador de un enganche de sujección de una brida y que forma el mango de la banderillao parte que se desprende y el otro de contención de una brida inferior y de un arpon metalico.
Patent ES-312364-A1 (ES)
Title: Polyolefine cellular products
IPC: C08F255/02
Filed: 1965-04-28
Abstract: The invention comprises an aliphatic polyolefin cellular product which is grafted and cross-linked by polymerized units of a compound containing two non-conjugated ethylenically-unsaturated double bonds. The cellular product is obtained by simultaneously foaming and polymerizing the compound. The polyolefin is preferably a polymer of an a -olefin of formula RCH=CH2, where R is an alkyl radical of 1 to 3 carbon atoms, e.g. ethylene and propylene. The double bonds of the cross-linking compound may be activated by the presence of a double bond between a carbon atom in an a -position and another atom. In the examples, the compounds used are divinylbenzene, ethylene dimethacrylate, N,N1-methylene-di-acrylamide and divinyl sulphone the foaming agents used are azocarbonamide and zinc acetate, carbon tetrachloride, 1,2-dichloro-tetrafluoroethane, N,N1-dinitroso-N,N1-dimethyl-terephthalamide and benzene-sulphonylhydrazide. In Example 3 ozonized polypropylene is used and in Example 4 polyethylene mixed with ethylene-vinyl acetate copolymer.
Patent ES-337385-A1 (ES)
Title: Apparatus for forming fibers
IPC: C03B37/04
Filed: 1967-02-28
Abstract: Fibres of glass and like vitreous material are made by directing a stream of molten material 14 on to a multi-layer 11-13 of foraminous material within and in contact with the wall of a rotor 3, the wall being formed with apertures 6 through which the molten material is forced by centrifugal action. It is stated the layers 11-13 result in more even distribution of the molten material over the whole width of the perforated section. Wire screen and/or perforated metal plates with the same or differing hole spacings may be used for the layers 11-13.
Patent ES-340252-A1 (ES)
Title: A cable connector
IPC: H01R4/62
Filed: 1967-05-08
Abstract: Each half of a cable connector comprises a tubular body portion 2 with a tapering internal surface 15 containing cable gripping jaws 16, 17 whose parts are compressed together when the jaws are forced towards the narrow end of the body under the action of an asymmetrical wedge 9 driven in a passage 3 in the central part 1 of the connector, the force being transmitted by the moveable member 13 in the wider end of the body. In an alternative arrangement, not shown, one symmetrical wedge is employed to lock both halves of the connector simultaneously. Wedges are driven into position by a ram using an explosive charge, and an anvil which deforms the narrow end of the wedge to retain it in position (Figs. 8 and 9, not shown). Cable 36 comprises aluminium strands on a steel core, jaw set 17 having two sections with internal teeth 25 to grip the aluminium strands, and jaw set 16 comprising a number of internally toothed sections 22 to grip the bared steel core in a plane normal to the grip of jaw set 17. If the cable consists of a single metal only one pair of gripping jaws is employed. A compressible plastics spacer 30 held in position by the jaws allows their relative adjustment during the gripping action. An annular plastics member (27, Figs 2, 4, 5) facilitates the insertion of the cable into the connector. An abrasive material such as silicon or carborundum dust may be used in suspension in light oil on the cable section gripped by the jaws, to increase the frictional resistance and reduce corrosion effects. Sealing members may be placed at the end of tube 2. One half of the connector body may be used alone as a cable termination.
Patent ES-341700-A1 (ES)
Title: Method of Granulating Fertilisers
IPC: B01J2/12
Filed: 1967-06-12
Abstract: A granular mixed fertilizer is produced from ingredients in powder form by heating to effect drying and then granulating (by superficial softening) in the same or separate apparatus. Drying and granulating may take place in succession in a cylinder rotating about a horizontal axis and heated externally or internally, e.g. by flame heating. At least one of the ingredients may be a phosphate, nitrate, chloride or sulphate of potassium, ammonium or magnesium or a superphosphate. Recycle material may be included. The ingredients may be in powder form of particle size 0À2-1À5 mm. Ammonium nitrate may be added as a 95- 99% solution. The product may have a grain size of 2-4 mm., apparent density of 0À9-1À1 gm/c.c., hardness of 5-10 kgm., free moisture content of less than 0À5% ,breaking strain of less than 3 kgm, and a porosity of 0À01 c.c./gm.
Patent ES-342339-A1 (ES)
Title: Regulation of heat and estrus with 1-(p-(beta-diethylaminoethoxy)phenyl) - 1,2 - diphenylchloroethylene
IPC: A23K/
Filed: 1967-06-26
Abstract: Feed compositions for the regulation of heat and estrus in female domestic animals comprise, as active ingredient, 1-[p-(#-diethylaminoethoxy) phenyl] - 1,2 - diphenylchloroethylene and conventional feedstuffs and nutrients.