baber/WOPTO huggingface dataset:
Patent EP-4094262-A1 (EP)
Inventor: KENNINGTON AARON
IPC: G16H10/40
Filed: 2021-01-08
Abstract: The multi-parameter data produced via flow cytometry and other biological analyses techniques can generate enormous amounts of data, which can take extensive time and/or computational resources to complete. Embodiments provided herein allow for adaptive sub-sampling of such data prior to analysis, allowing for such analyses to be performed while satisfying certain performance criteria. Such performance criteria may include, for example, keeping the latency of the analysis below a specified duration. This can allow analysis of data to be performed in real time as the data is generated, e.g., as flow cytometry data is generated by a cell counter or other flow cytometry instrument. This can also permit for data analyses to be iteratively developed or improved in less time by adaptively sub-sampling the data prior to re-analysis, so that the total time between iterations is reduced.
Patent EP-4100754-A1 (EP)
Title: Devices for manipulating electromagnetic fields in a magnetic resonance system
Inventor: SAHA SHIMUL
IPC: H01Q15/00
Filed: 2021-02-03
Abstract: There is provided a method of producing a device (20) for manipulating a magnetic field of RF radiation from one or more RF antennas (53) in an MR system (50). The method comprises: determining a target resonance quality factor and/or a target resonant RF frequency of the device (20) based on at least one characteristic of the one or more RF antennas (53); determining a design of the device (20) to provide the device with the determined target resonance quality factor and/or target resonant RF frequency; and making the device (20) in accordance with the design. The device (20) comprises: a plurality of conductive elements (12, 22) arranged in an array (14), wherein the array (14) is arranged to redistribute energy between electric and magnetic fields of the RF radiation at a resonant RF frequency when receiving the RF radiation the RF radiation having an RF wavelength greater than a respective dimension of each conductive element (12, 22); and a dielectric material (26), wherein the dielectric material (26) has a dielectric permittivity and a loss tangent.
Patent EP-4103686-A1 (EP)
Inventor: COCIANCICH MATTEO
IPC: C12N1/20
Filed: 2021-02-12
Abstract: The present invention refers to an improvement in stabilizing the biological methanogenesis process by biocatalysts, e.g., Archaea. In particular, the present invention refers to methods for adapting and stabilizing the biocatalyst and the methanogenesis process. More particularly, this method provides an improvement for and during unstable or excessive fluctuation in the energy load and thereupon fluctuations regarding the supply of feed gas.
Patent EP-4118080-A1 (EP)
Inventor: VOISIN-CHIRET ANNE-SOPHIE
IPC: A61K31/4427
Filed: 2021-03-12
Abstract: The present invention relates to compounds, compositions and methods for treating cancers and disorders of cell proliferation and more particularly, methods of making and using compounds that modulate at least one of the proteins chosen from Bcl-2, Mcl-1, Bcl-X L , Bcl-w, Bfl-1 and Bcl-B, in particular Bcl-2 protein, or BC1-X L  and/or Mcl-1 proteins; said compounds may be contained in pharmaceutical compositions and used as therapeutic agents.
Patent EP-4100528-A1 (EP)
Inventor: ODATE SHOBU
IPC: A61K31/7125
Filed: 2021-02-05
Abstract: L'invention concerne des compositions et des procédés d'édition, par exemple d'introduction de cassures bicaténaires, dans le gène KLKB1. L'invention concerne également des compositions et des méthodes de traitement de sujets présentant un oedème héréditaire (HAE).
Patent EP-4107087-A1 (EP)
Inventor: ZACHERLE MATTHEW E
IPC: B65D71/40
Filed: 2021-02-22
Abstract: Aspects of the disclosure relate to a top engaging article carrier for packaging one or more articles and a blank for forming the carrier. The article carrier comprises an engaging panel (12A, 12B) having at least one ply and comprising; a first side edge (El), a first end edge (E2) and a comer (BC) defined by the first side and end edges (El, E2). The engaging panel (12A, 12B) comprises a corner area (18) extending between the comer (BC) and an article-receiving aperture (Al, A2) in the engaging panel (12A, 12B). The aperture (Al, A2) comprises a first engaging edge (E4) at a position across the corner area (18) from the corner (BC). The first engaging edge (E4) is curved. The first engaging edge (E4) has a radius of curvature (r3) greater than the radius (rl) of the comer aperture (Al, A2).
Patent EP-4111611-A1 (EP)
Inventor: JONG JAMES J
IPC: H04W88/06
Filed: 2021-02-23
Abstract: A method for communicating with a legacy terminal supporting a legacy air interface and a new terminal supporting a next generation air interface including: assigning a same carrier to the legacy terminal and the new terminal; receiving a terminal identifier and an optional payload for transmission at a MAC/RLC layer; determining if the terminal identifier is associated with the legacy terminal or the new terminal; composing, based on the determining, a burst header; formatting, a burst including the burst header and the optional payload; and transmitting the burst. In the method, the burst header is set to one of the one or more valid burst headers when the burst is associated with the legacy terminal, and the burst header is set to one of the one or more undefined burst headers when the burst is associated with the new terminal. Focus is put on Geo Mobile Radio, GMR, for satellite systems with the definition of new burst formats, wherein the new burst format is indicated by invalid or reserved MCS values in the legacy burst format header.
Patent EP-4146368-A1 (EP)
Title: Liquid treatment cartridge
Inventor: ZÖLLER JOCHEN
IPC: B01D35/157
Filed: 2021-03-31
Abstract: A liquid treatment cartridge (1) comprises a cap (17) for placement on a cartridge head section (3) of the liquid treatment cartridge (1). The cartridge head section (3) includes at least one liquid inlet port (6) and at least one liquid outlet port (7) for enabling a fluid-tight connection to a head part (12) of a liquid treatment system (2). The cap (17) comprises at least one port opening (18) that allows for establishing the liquid-tight connection with the at least one liquid inlet port (6) and the at least one liquid outlet port (7) of the cartridge head section (3) without removing the cap (17) from the cartridge head section (3). Furthermore, the cap (17) comprises at least one protruding locking part (19) for releasably locking the cartridge head section (3) within the head part (12) of the liquid treatment system (2).
Patent EP-4138549-A1 (EP)
Title: Modèle animal pour l'étude d'immunothérapie anticancéreuse
Inventor: CASTELLANI VALÉRIE
IPC: A61K39/00
Filed: 2021-04-21
Abstract: L'invention se rapporte à un embryon de gallinacé chimérique comprenant deux types de cellules exogènes : a. au moins une population de cellules cancéreuses, et b. au moins une population de cellules immunitaires, lesdites cellules cancéreuses exogènes étant présentes dans au moins un tissu dudit embryon, et lesdites cellules immunitaires exogènes étant présentes dans au moins un tissu dudit embryon et/ou circulant dans les vaisseaux sanguins dudit embryon.
Patent EP-4138636-A1 (EP)
Title: Utilisation d'images en temps réel pour la visualisation en réalité augmentée d'un outil chirurgical ophtalmique
Inventor: GOVARI ASSAF
IPC: A61B1/00
Filed: 2021-04-12
Abstract: La présente invention concerne un système comprenant un processeur et un dispositif d'affichage. Le processeur est configuré pour : (a) recevoir, à partir d'une caméra insérée dans un oeil d'un patient, au moins une image optique d'au moins une région d'intérêt (ROI) de l'oeil, (b) recevoir, en provenance d'un système de suivi de position (PTS), un signal de position indiquant une position d'un instrument médical traitant l'oeil, (c) enregistrer l'image optique et le PTS dans un système de coordonnées commun, et (d) estimer la position de l'instrument médical dans l'image optique. L'affichage est configuré pour visualiser au moins la ROI et l'instrument médical.
Patent EP-4143614-A1 (EP)
Inventor: CANGEMI MICHAEL JEROME
IPC: G02B1/115
Filed: 2021-04-13
Abstract: An anti-reflective coating including a plurality of first layers, which each comprise a first material with a relatively high refractive index, and a plurality of second layers, which each comprise a second material with a relatively low refractive index. A total thickness of the first layers comprised of the first material is about 120 nm or less. Additionally, the anti-reflective coating is configured to absorb about 0.25% or less of light for a single reflection of the average of the s- and p-polarizations of the light, at every wavelength between about 425 nm to about 495 nm, when the light is propagating under total internal reflection.
Patent EP-4153623-A1 (EP)
Title: Novel cov-2 antibodies
Inventor: PAPASOTIRIOU IOANNIS
IPC: C07K16/10
Filed: 2021-05-18
Abstract: The present invention provides a novel method for the production of truly fully human monoclonal antibodies against SARS-CoV-2 using isolated human blood cells. These antigens may include but are not limited to peptide sequences found in envelope or spike proteins of SARS-CoV-2 proteins.
Patent EP-4150419-A1 (EP)
Inventor: KLEIN CARSTEN ANDREAS
IPC: G05B19/418
Filed: 2021-05-12
Abstract: Die Erfindung betrifft ein System (1) und Verfahren zur Steuerung einer aus mehreren Anlagenteilen (3) bestehenden Produktionsanlage (2), insbesondere einer Produktionsanlage (2) zur Erzeugung von Industriegütern wie metallischem Halbzeug, umfassend: eine Anlagenautomation (4) zur Überwachung und Steuerung und/oder Regelung des Produktionsprozesses innerhalb der Produktionsanlage (2), ein Produktionsplanungssystem (5) mit Informationen über die in der Produktionsanlage (2) herzustellenden Produkte, einen Modellgenerator (6) zur Erzeugung wenigstens eines Vorhersagemodells (7) für das aktuell in der Produktionsanlage (2) hergestellte Produkt und/oder für die zukünftig herzustellenden Produkte, wobei der Modellgenerator (6) die Ergebnisse der Überwachung der Produktionsanlage (2) bei der Erzeugung des wenigstens einen Vorhersagemodells (7) berücksichtigt, einen Produktionsoptimierer (8) zur Bestimmung eines optimierten Produktionsprozesses innerhalb der Produktionsanlage (2) auf Basis der Daten der Anlagenautomation (4), des Produktionsplanungssystems (5) und des von dem Modellgenerator (6) erzeugten Vorhersagemodells (7), wobei der Produktionsoptimierer (8) die produktionstechnischen Vorgaben der einzelnen Anlagenteile (3) berücksichtigt, und eine Produktionsanlagensteuerung (9) zur Erzeugung von Sollvorgaben für die Anlagenautomation (4) auf Basis des vom Produktionsoptimierer (8) bestimmten optimierten Produktionsprozesses.
Patent EP-4153347-A1 (EP)
Title: Thermally expandable cellulose-based microspheres having low expansion temperatures
Inventor: ANDREASSON BO
IPC: B01J13/14
Filed: 2021-05-19
Abstract: The invention relates to thermally expandable microspheres comprising a polymeric shell surrounding a hollow core, wherein the hollow core comprises a blowing agent, and the polymeric shell comprises a carboxylate-functionalised cellulose, wherein the thermally expandable microspheres have a temperature at which expansion starts, Tstart, of from 80°C to less than 135°C. The invention further relates to a process for preparing expandable microspheres as well as to thermally expandable microspheres obtained by such process, the process comprising mixing a carboxylate-functionalised cellulose, an organic solvent, a blowing agent and, optionally, a polymer shell enhancer and then spraying the thus obtained mixture into a drying equipment to produce the thermally expandable microspheres having a polymeric shell surrounding a hollow core, in which the polymeric shell comprises the carboxylate-functionalised cellulose, and the hollow core comprises the blowing agent.
Patent EP-4168447-A1 (EP)
Title: Anticorps se liant à cd3 et cd19
Inventor: FREIMOSER-GRUNDSCHOBER ANNE
IPC: A61P35/00
Filed: 2021-06-17
Abstract: La présente invention concerne de manière générale des anticorps qui se lient à CD3 et CD19, par exemple pour activer des lymphocytes T. De plus, la présente invention concerne des polynucléotides codant pour de tels anticorps, et des vecteurs et des cellules hôtes comprenant de tels polynucléotides. L'invention concerne en outre des procédés de production des anticorps et des procédés d'utilisation de ceux-ci dans le traitement d'une maladie.
Patent EP-4172189-A1 (EP)
Inventor: HUDECEK MICHAEL
IPC: C07K14/725
Filed: 2021-06-29
Abstract: The present invention relates to a polypeptide encoding a SLAMF7-binding chimeric antigen receptor (CAR), a polynucleotide encoding the SLAMF7-binding CAR polypeptide, a recombinant immune cell (preferably recombinant lymphocyte, more preferably recombinant T cell) comprising the polynucleotide, a method for producing recombinant immune cells and a pharmaceutical composition comprising recombinant immune cells. The recombinant immune cells and the pharmaceutical composition of the present invention may be used in methods for treating cancer in a patient thereby providing an improved treatment regimen. The inventors of the present application demonstrated that SLAMF7 CAR T-cells prepared by Sleeping Beauty gene transfer confer superior anti-myeloma efficacy in vivo compared to SLAMF7 CAR T-cells prepared by lentiviral gene transfer. Hence, SLAMF7 CAR T-cells that are prepared by virus-free SB gene transfer possess greater anti-myeloma efficacy and therapeutic potential, which leads to significantly improved clinical activity, and significantly improved clinical outcome.
Patent EP-4089810-A1 (EP)
Inventor: ZHU YAN
IPC: H01M50/186
Filed: 2021-01-08
Abstract: A battery (100), a battery module, a battery pack (200), and an electric vehicle are provided. The battery (100) includes a metal housing (11), a packaging member, and multiple electrode core assemblies (12). The packaging member includes two packaging portions (13) that are arranged opposite to each other. The packaging member has an internal space. The two packaging portions (13) are joined at a predetermined position to divide the internal space of the packaging member into multiple sealed accommodating cavities. At least one sealed accommodating cavity is provided with the electrode core assembly (12). The metal housing (11) is sleeved outside the packaging member.
Patent EP-4167981-A1 (EP)
Inventor: WILSON GLYNN
IPC: A61K9/00
Filed: 2021-06-21
Abstract: Provided herein are oronasal formulations including a cannabinoid and N-L-alpha-aspartyl-L-phenylalanine 1-methyl ester (APM). Also provided are methods of using the formulations.
Patent EP-4095245-A1 (EP)
Inventor: MASHIMO TOMOJI
IPC: C12Q1/68
Filed: 2021-01-25
Abstract: It has been found that by mixing a single-stranded probe DNA whose cleavage can be detected in a reaction system containing a CRISPR-Cas3 system and a sample from which to detect a target DNA, it is possible to detect the target DNA in the sample by using, as indication, a signal generated by the cleavage of the single-stranded probe DNA.
Patent EP-4172323-A1 (EP)
Title: Viruses engineered to promote thanotransmission and their use in treating cancer
Inventor: SCHMIDT DARBY RYE
IPC: C12N7/00
Filed: 2021-06-29
Abstract: In certain aspects, the disclosure relates to a virus engineered to comprise one or more polynucleotides that promote thanotransmission by a target cell. Thanotransmission is communication between cells that is a result of activation of a cell turnover pathway in a target cell, which signals a responding cell to undergo a biological response. Methods of promoting thanotransmission by a target cell, methods of promoting an immune response in a subject, and methods of treating cancer in a subject are also disclosed.
Patent EP-4098130-A1 (EP)
Inventor: NABESHIMA TAKUMA
IPC: A23L7/109
Filed: 2021-01-29
Abstract: Provided are noodles having a preferable texture with good elasticity, viscosity, and crispness, and capable of maintaining a flavor of a sauce during chewing. Provided is also a method for producing noodles, including extruding a dough at a pressure of 40 kgf/cm<sup>2</sup> to 120 kgf/cm<sup>2</sup>, in which the dough is prepared from a raw material flour containing durum wheat flour and moderate wheat flour having a crude protein content of 10% or more at a mass ratio of 1 : 99 to 29 : 71.
Patent EP-4183012-A1 (EP)
Inventor: GARDNER TIMOTHY
IPC: H02G3/08
Filed: 2021-07-14
Abstract: A charging system for installation into a block wall includes a docking unit, a cover unit and a charging unit. The docking unit includes a docking unit hollow body with an open front face, and a back plate closing the rear face and an electrical connector positioned within the docking unit hollow body. The cover unit includes a cover unit hollow body for insertion into the docking unit hollow body. The charging unit has a charging unit hollow body for insertion into the docking unit hollow body; and a charger module is located in the charger housing and the charging module includes contacts for connecting to the docking unit electrical connector, and a cable connector for connecting a charging cable. A method of installing the charging system in a block wall, comprises constructing the wall; installing the docking unit; attaching a cover unit the docking unit; and subsequently removing the cover unit from the docking unit and attaching a charging unit to the docking unit so that the charger module contacts engage the contacts on the docking unit electrical connector.
Patent EP-4100589-A1 (EP)
Inventor: PHAM PHI-OANH R
IPC: E04B1/86
Filed: 2021-02-02
Abstract: An acoustical ceiling panel including a first layer having a first major surface opposite a second major surface and a side surface extending therebetween, a second layer having a first major surface opposite a second major surface and a side surface extending therebetween, and a sealing layer having a first major surface opposite a second major surface and a side surface extending therebetween. The sealing layer may be positioned between the first major surface of the first layer and the second major surface of the second layer. The side surface of the sealing layer may extend beyond the side surface of the first layer and the side surface of the second layer.
Patent EP-4189916-A1 (EP)
Inventor: CASTELLANOS ZAMORA DAVID
IPC: H04L9/40
Filed: 2021-07-29
Abstract: An authentication server (16) in a home network (18) of a wireless device (10) receives, from a network node (14), a request (20) for authentication data (22) based on which to authenticate the wireless device (10). The request (20) indicates a serving network (12) on which the authentication data (22) is to be based. The authentication server (16) checks whether or not the network node (14) is authorized to request authentication data (22) that is based on the indicated serving network (12).
Patent EP-4104882-A1 (EP)
Inventor: MATSUMOTO IPPEI
IPC: A61M5/32
Filed: 2021-02-12
Abstract: Provided is an injection device including an engagement releasing mechanism configured to release engagement between a plunger and an engaging member and to cause the plunger to be located at an end point in a manner that the plunger moves from a start point toward the end point by an urging force of a plunger urging portion and the plunger and the engaging member rotate relative to each other around a central axis.
Patent EP-4185778-A1 (EP)
Inventor: Cottet Clément
IPC: F04D29/32
Filed: 2021-07-15
Abstract: The invention relates to an assembly for an aircraft turbine engine, including an unducted propeller blade (10) and a system (34) for setting the pitch of the blade (10) and further comprising: - a blade (10) of which the root (14) has a bulbous portion (32); - a system (34) for setting the pitch of the blade (10) about a pitch setting axis (A), the pitch setting system (34) comprising a cup (58), which is intended to be placed inside the outer casing (73), has a flared open top end for axial insertion of the root (14) and in which the root (14) of the blade (10) is axially affixed by a locking member (52); the assembly being characterised in that it further comprises at least one radial retention prong (77) in a radial space (E) reserved between the wall (58a) of the cup (58) and the root (14).
Patent EP-4188889-A1 (EP)
Inventor: CAI LING
IPC: C03C23/00
Filed: 2021-07-26
Abstract: L'invention concerne un article, comprenant : une surface supérieure; une surface inférieure; un plan intermédiaire entre la surface supérieure et la surface inférieure; un trou d'interconnexion s'étendant depuis la surface supérieure jusqu'à la surface inférieure, de telle sorte que le trou d'interconnexion présente un diamètre au niveau de la surface supérieure et/ou de la surface inférieure de D1; le trou d'interconnexion présente un diamètre au niveau du plan intermédiaire de Dw; et une valeur de (Dw/D1)×100 se situe dans une plage de 4 à 85. L'invention concerne une composition à base de silicate comprenant : 40-80 % en mole de SiO2, >0-25 % en mole de MO, >0-15 % en mole d'Al2O3, >0-15 % en mole de B2O3, >0-5 % en mole de SnO2 et éventuellement ≥0-5 % en mole de P2O5, de telle sorte que MO représente la somme de BeO, de MgO, de CaO, de SrO et de BaO.
Patent EP-4108761-A1 (EP)
Title: Method for producting cell aggregate
Inventor: SUZUKI KOHEI
IPC: C12M3/00
Filed: 2021-02-19
Abstract: This is to provide a substrate for producing cell aggregates, a method for producing the same, a method for producing cell aggregates, and a method for improving cell utilization efficiency at the time of producing the cell aggregates.A substrate for producing cell aggregates provided with a plurality of spots which comprises a polymer containing a recurring unit derived from a monomer represented by the following formula (I):[wherein U<sup>a1</sup>, U<sup>a2</sup>, R<sup>a1</sup> and R<sup>a2</sup> are as defined in the present specification and claims] on a substrate having an ability to inhibit adhesion of cells, wherein a ratio of a total area of the spots to a surface area of the substrate is 30% or more, a diameter of each spot is 50 to 5,000 µm, and a distance between the spots is 30 to 1,000 µm, a method for producing the same, and a method for producing cell aggregates using such a substrate and a method of improving cell utilization efficiency at the time of producing the cell aggregates.
Patent EP-4088668-A1 (EP)
Title: Bendable endoscopic linear cutter anastomat and assembly thereof
Inventor: LIU QING
IPC: A61B17/072
Filed: 2021-01-11
Abstract: Disclosed are a bendable endoscopic linear cutting anastomat and assembly thereof, comprising an anastomat jaw, a turning connection block, an assembly inner core and a cutting blade assembly; the assembly inner core comprises an inner core shell and an inner core connection block fixedly mounted in the inner core shell; the front end of the turning connection block is hinged to the rear end of the anastomat jaw, a first vertical rotation shaft is formed at the hinge, the rear end of the turning connection block is hinged to the front end of the inner core connection block, a second vertical rotation shaft is formed at the hinge; the cutting blade assembly penetrates through the inner core connection block, the turning connection block and the anastomat jaw, and can slide forwards and backwards. On the basis of the above-mentioned dual rotation shafts (centers), the present invention also adopts a U-shaped left and right bending sheet which controls the bending process by the turning of the inner core connection block. By means of the above-mentioned arrangement in the present invention, the bending radius can be increased, thereby reducing the firing force during cutting and anastomosing, and enabling a doctor to have a better operation hand feeling. In addition, a larger bending angle can be achieved, so that the doctor has a better operation space.