baber/WOPTO huggingface dataset:
Patent ZA-200901220-B (ZA)
Title: Method of optimizing the treatment of philadelphia-positive leukemia with abl tyrosine kinase inhibitors
Inventor: GATHMANN INSA
IPC: A61P/
Filed: 2009-02-20
Abstract: The present invention provides a method of treating Philadelphia positive (Ph+) leukemia, such as Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ ALL) or chronic myeloid leukemia (CML), in a human patient population comprising the steps of 
(a) administering a predetermined fixed amount of a Bcr-Abl tyrosine kinase inhibitor, such as Imatinib, or a pharmaceutically acceptable salt thereof to human patients suffering from a Ph+ leukemia, 
(b) collecting at least one blood sample from said patients, 
(c) determining the plasma trough level (Cmin) of the Bcr-Abl tyrosine kinase inhibitor or of a metabolite thereof as well as the MMR rates, 
(d) assessing a discrimination potential of trough plasma concentrations for MMR and identifying a Cmin threshold for optimal sensitivity and specificity and 
(e) adjusting the dose of the inhibitor of the Bcr-Abl tyrosine kinase or a pharmaceutically acceptable salt thereof applied to the individual patients from said patient population and, optionally, future patients suffering from a Ph+ leukemia in a manner that a Cmin is achieved in each single patient equal to or higher than the Cmin threshold obtained under step (d).
Patent ZA-202300353-B (ZA)
Title: Lateral flow assay device for detection of analytes and method of detection thereof
Inventor: VANGALA RAJANIKANTH
Filed: 2023-01-09
Abstract: The present invention relates to a lateral flow assay device for detection of an analyte in a sample and a method of detection thereof. The present invention provides a quantitative assay for detection of an analyte in a sample. The present invention also provides a conjugate. The present invention provides a method of diagnosing COVID 19 in a patient.
Patent GR-1003535-B (GR)
Title: Natural cosmetic product and preparation method thereof
Inventor: VOURAZERI EVANGELOU NANTEZNTA
Filed: 2000-04-06
Abstract: Natural cosmetic product in the oil form. It is composed of 20 capsules of E vitamin (Eviol), 3/4 almond oil, and 1/4 olive oil by weight of 100gr. The said product can be used for the quick regeneration of the skin cells (it supresses the face blotches), the safe and slight whitening of the skin, as well as the perfect and hygienic nutrition thereof.
Patent GR-1004728-B (GR)
Title: Multi-articulated welding arm for automatic welding machines
Inventor: KARABASIS STAVROS
IPC: B23K9/28
Filed: 2003-09-22
Abstract: he invention relates to a welding machine's multi-articulated welding arm composed of the articulated sub-arm 5 on the base comprising the plate 1 rotating about the vertical axis, the caps 3, and the sub-arms 16 & 5 articulated by mediation of thescrewable carrier 12. The sub-arm 5 bears at the top the head sections 19&20, which are mutually articulated via the screw 36 and liable to oscillate with the help of the electromotor 31 and the eccentric 11 which is placed at the shaft 32 and conveys the motion to the shaft 25. The sub-arms 5, 16 are connected via the pneumatic piston 35, with screws 34. The sub-arms 5,16 can modify their operation angle formed between them in accordance to the expansion of the rod of the pneumatic piston 35. In this way, the head is capable of automatically approaching the piece to be welded even while operating. Furthermore, the sub-arms 5, 16 are slightly regulated on the left or the right position by means of the screw 22 of the screwable carrier 12. The head sections 19, 20 of the upper part of the sub-arm 16 are oscillating to increase the welding width so that the rotation of the whole arm on the rotary plate 1 of the base or the rotation of the head section 20 can enable welding under angle.
Patent GR-1004591-B (GR)
Title: Reflector for fluorescent lamps
Inventor: PIPERIDIS STAVROS
IPC: F21V19/00
Filed: 2003-10-20
Abstract: t is disclosed herein a reflector 1 meant to concentrate and direct, at desire, the light of fluorescent lamps. It is presented in a uniform parabolic form of thin reflective synthetic film, and bears transversally positioned lamp-holding pieces 4 made of thin flexible synthetic film and liable to fix the reflector 1 on the fluorescent lamps 3. The lamp-holding pieces in question 4 have in their middle adequately-shaped openings 6 permitting the lamp 3 to pass through; the reflector thus retained on the fluorescent lamp 3 is able to rotate, with respect to the lamp 3, by some degrees in order to concentrate the light in the desired direction.
Patent IN-157649-B (IN)
Inventor: GOUGH ROBERT PETER
IPC: C23G/
Filed: 1981-10-13
Abstract: Wire (50) is passed through apparatus (51) having two treatment zones. The first treatment zone contains six wire cleaning heads (15-20) and the second treatment zone contains two wire cleaning heads (13 & 14). Each cleaning head consists of a primary cylindrical chamber (72) flanked by two secondary cylindrical chambers (73) of substantially smaller diameter. The wire passes axially through the cylinders. A working fluid such as dilute alkali, water or an organic solvent is pumped into the primary cylindrical chamber via a tangentially aligned inlet (74). It circulates in the primary chamber (72) and leaves via the secondary chamber with a very high annular velocity due to the reduction in the diameter of circulation. The high circulation speed causes vibration in and around the wire in the secondary chambers with resultant abrasion of the surface of the wire. In an alternative embodiment up to all but one of the cleaning heads may be replaced by dies. Separate fluids are used in each treatment zone and prevented from mixing by a jet of high pressure air directed obliquely onto the wire to repel any flow of fluid along the wire. Similar jets prevent escape of fluid out of the ends of the apparatus.
Patent IN-157661-B (IN)
Inventor: WEST LESLIE LEONARD
IPC: H04R11/00
Filed: 1982-12-30
Abstract: A method of producing a transducer in which the fine tolerances are obtained by a two stage moulding process. Features include retention of the coil by the moulding process and accurate dimensioning of the magnet by depression of the soft iron core.
Patent MX-350805-B (MX)
Title: Process for the extraction and analysis of materials and equipment therefor.
Inventor: NASER QURESHI
IPC: G01Q80/00
Filed: 2010-04-20
Abstract: Disclosed is a method and equipment for extracting a sample from a material and perform the analysis thereof. The invention has a leading tip, which is approached to the also leading sample surface, which is subjected to an electric potential so as to extract the sample material. The potential is mainly applied in a pulsed manner, and may vary according to the material to be analysed, the temperature thereof, the tip closeness, amongst other aspects. The device may work at vacuum or in liquid or gaseous media. In case of the vacuum extraction, the application of the extraction potential is followed by the application of an accelerator voltage, which may be a ionizing voltage for leading the extracted species towards the outlet where the detection system is to be located. In a liquid or gaseous medium, the fluid will drag the extracted species. In all cases the species will be led to the outlet where the analysis technique is located, this may be mass spectrometry or plasma inductively coupled, amongst others.
Patent MX-339671-B (MX)
Title: Solid oral form with dual release profile, containing multiparticulates.
Inventor: FLORENCE GUIMBERTEAU
IPC: A61K9/26
Filed: 2009-04-17
Abstract: The invention relates to a solid form intended for the oral administration of at least one active agent and capable of ensuring a dual mechanism for the release of said active agent, whereby the first release is conditioned by time and the second release is conditioned by pH. The invention is characterised in that the active agent is present in the form of a microparticulate system, the microparticulates of which include a core which is made up entirely or partly of said active agent and coated with at least one layer which conditions the release profile of the active agent and which is formed by a material containing at least: (i) 25% to 75% by weight, relative to the total weight of the coating, of at least a polymer A that is insoluble in the gastrointestinal fluids, (ii) 25% to 75% by weight, relative to the total weight of the coating, of at least a polymer B that has a solubilisation pH value in the pH range of from 5 to 7, and (iii) 0 to 25% by weight, relative to the total weight of the coating, of at least one plasticiser, said polymers A and B being present in a polymer(s) B/polymer(s) A weight ratio that is at least equal to 0.25. The invention also relates to a method for preparing this solid form and the corresponding microparticulates.
Patent MX-342709-B (MX)
Title: Treatment of cancer.
Inventor: MARK DAVIS
IPC: A61K45/06
Filed: 2010-09-15
Abstract: Provided are methods relating to compositions that include a CDP- topoisomerase inhibitor, e.g., a CDP-camptothecin or camptothecin derivative conjugate, e.g., CRLX101.
Patent MX-346129-B (MX)
Title: Composite pavement structures.
Inventor: CALVIN T PEELER
IPC: E01C7/30
Filed: 2010-12-21
Abstract: A composite pavement structure comprises a wearing course layer and a base course layer disposed below the wearing course layer. The base course layer comprises aggregate and an elastomeric composition. The elastomeric composition comprises the reaction product of an isocyanate component and an isocyanate-reactive component. The isocyanate component comprises a polymeric isocyanate, and optionally, an isocyanate-prepolymer. The isocyanate-reactive component comprises a hydrophobic polyol and a chain extender having at least two hydroxyl groups and a molecular weight of from about 62 to about 220. The chain extender is present in the isocyanate-reactive component in an amount of from about 1 to about 20 parts by weight based on 100 parts by weight of the isocyanate-reactive component. The wearing course layer comprises aggregate which is the same or different than the aggregate of the base course layer. Methods of forming the composite pavement structure are also disclosed.
Patent MX-336498-B (MX)
Title: Identification, assessment, and therapy of cancers with innate or acquired resistance to alk inhibitors.
Inventor: MANO HIROYUKI
IPC: G01N33/574
Filed: 2011-02-04
Abstract: Described herein are compositions, kits, and methods for determining whether subjects having cancer(s) positive for ALK mutations are likely to respond to treatment with an ALK inhibitor and/or whether a patient having such cancer(s) is likely to have a relatively slower disease progression. Further described are methods for prognosing a time course of disease in a subject having such cancer.
Patent MX-337210-B (MX)
Title: Asymmetric tibial components for a knee prosthesis.
Inventor: WENTORF MARY S S
IPC: A61F2/38
Filed: 2011-07-22
Abstract: An orthopaedic tibial prosthesis includes a tibial baseplate with an asymmetric periphery which promotes proper positioning and orientation on a resected tibia, while also facilitating enhanced kinematics, soft-tissue interaction, and long-term fixation of the complete knee prosthesis. The asymmetric baseplate periphery is sized and shaped to substantially match portions of the periphery of a typical resected proximal tibial surface, such that proper location and orientation is evident by resting the baseplate on the tibia. The baseplate periphery provides strategically positioned relief and/or clearance between the baseplate periphery and bone periphery, such as in the posterior-medial portion to prevent deep-flexion component impingement, and in the anterior-lateral portion to avoid undue interaction between the anatomic iliotibial band and prosthesis components.
Patent MX-362563-B (MX)
Title: Crystalline (8s,9r)-5-fluoro-8-(4-fluorophenyl)-9-( 1-methyl-1h-1,2,4-triazol-5-yl)-8,9-dihydro-2h-pyrido[4,3,2-de]p hthalazin-3(7h)-one tosylate salt.
Inventor: BING WANG
IPC: A61K31/5025
Filed: 2011-10-20
Abstract: Provided herein are (8S, 9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-lH-1,2,4-tri azol-5- yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7 H)-one tosylate salt forms, including crystalline forms, and methods of their preparation. Pharmaceutical compositions comprising a (8S,9R)-5-fiuoro-8-(4-fluorophenyl)-9-(1-methyl-1 H-1,2,4-triazol-5-yl)-8,9-dihydro-2H- pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate salt are also provided, as are methods of using (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1 H-1,2,4-triazol-5-yl)-8,9-dihydro-2H- pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate salt to treat a disease or condition, such as a cancer.
Patent MX-342993-B (MX)
Title: Process to obtain random copolymers derived from itaconic acid and/or its isomers and sodium alkenyl sulfonates and use of the product thereof.
Inventor: VIOLETA YASMÍN MENA CERVANTES
IPC: C08F222/02
Filed: 2013-04-25
Abstract: A process for obtaining random copolymers from itaconic acid and/or isomers and sodium alkenyl sulfonates is by polymerization in an aqueous solution via free radicals at an acidic pH in the range from 1.0 to 3.5 and with a redox system as initiator. The copolymers can be used as calcium carbonate and calcium, strontium and barium sulfates mineral scale inhibitors and as dispersants of clays, iron oxides, calcium carbonate and strontium, barium and calcium sulfates. Random copolymers prevent and control damage to the formation by mineral salts scale that occurs in an oil reservoir, obstruction of water injection and crude oil production pipelines, as well as in production rigs due to mineral scale precipitation, all this as a consequence of high levels of salinity of the formation water and incompatible mixtures of injection water and formation wáter. Random copolymers are characterized for being tolerant to high concentrations of divalent ions, such as calcium, magnesium, strontium a nd barium, and by the fact that for its application to the reservoir and to injection or production pipelines, treated water, sea water and water that is characteristic of the reservoir (formation water) can be used as means of transportation. On the other hand, the copolymers can also be used to inhibit and disperse mineral scale occurring in cooling systems and boilers used in the oil and chemistry industry. Furthermore, the random copolymers of the present invention are characterized for meeting internationally established environmental standards and are classified as particularly non-toxic and therefore they can be used in pipelines and equipment from oil and chemical industry that uses fresh water and sea water that are characteristic of offshore and inland facilities.
Patent MX-338336-B (MX)
Title: Modified insulin polypeptides and their uses.
Inventor: HO LILLIAN
IPC: C07K14/62
Filed: 2008-11-20
Abstract: Modified insulin polypeptides and their uses thereof are provided.
Patent MX-342668-B (MX)
Title: Synergistic interface system for a building network.
Inventor: CHRIS CASILLI
IPC: H04L12/24
Filed: 2012-08-24
Abstract: An interface system for a building includes at least one mobile computing device configured to read building information indicia positioned within the building, with the building information indicia defining indicia data. The at least one mobile computing device is in wireless communication with a building control system within the building. The building control system is configured to send control signals to a plurality of field devices within the building. The at least one mobile computing devices is configured to transmit indicia data defined by the building information indicia to the building control system. The building control system is configured to control the field devices based at least in part on the indicia data received from the mobile computing devices.
Patent MX-359235-B (MX)
Title: Method for preparing a composition comprising highly concentrated antibodies by ultrafiltration.
Inventor: KELBY LAU
IPC: B01D61/14
Filed: 2012-08-31
Abstract: The present invention provides a method for preparing a composition comprising highly concentrated antibodies by ultrafiltration in batch concentration mode having a first constant feed rate step and a second controlled feed rate step.
Patent MX-356635-B (MX)
Title: Fishing reel with a 180 degree rotating spool.
Inventor: MARK FRANCES KENDRA
IPC: A01K89/027
Filed: 2012-09-10
Abstract: The present invention provides a fishing reel that allows the caster to cast from either side of the spool or an in-line position. Starting from a spool position with the line on the spool in the same direction as the retrieve referred to as the in-line position, the line can be cast from this position, or the spool can be rotated 90 degrees in either direction from the in-line position for the cast. After the spool is rotated, the cast is discharged from the side of the spool in a direction perpendicular to the line on the spool. After the cast, the spool is returned to the starting position of the in-line position, with the line on the spool in the same direction as the retrieve. The line is then retrieved by turning a handle connected to a series of gears that engage the spool and thereby reel in the line.
Patent MX-364987-B (MX)
Title: Variant alpha-amylases from bacillus subtilis and methods of use, thereof.
Inventor: DAVID A ESTELL
IPC: C12N9/14
Filed: 2009-06-05
Abstract: Alpha amylases from Bacillus subtilis (AmyE), variants thereof, nucleic acids encoding the same, and host cells comprising the nucleic acids are provided. Methods of using AmyE or variants thereof are disclosed, including liquefaction and/or saccharification of starch. Such methods may yield sugars useful for ethanol production or high fructose corn syrup production. In some cases, the amylases can be used at low pH, in the absence of calcium, and/or in the absence of a glucoamylase.
Patent MX-356701-B (MX)
Title: Metal pigment- and solvent-containing pigment pastes, and use thereof for producing effect-producing solvent-containing coating materials.
Inventor: JORN LAVALAYE
IPC: C09D7/65
Filed: 2013-03-14
Abstract: The invention relates to flake-form effect pigment- and solvent-containing pigment pastes. The invention further relates to the use of the flake-form effect pigment- and solvent-containing pigment pastes in order to produce effect-producing solvent-containing coating materials. The invention further relates to a method for producing effect-producing solvent-containing coating materials.
Patent MX-347682-B (MX)
Title: A low drag, high pressure septum.
Inventor: DANIEL KIRK HYER
IPC: A61M25/06
Filed: 2013-02-20
Abstract: A septum is disclosed that can be utilized in a catheter assembly to selectively seal an opening in the catheter assembly. The septum has a tube portion and a plug portion. The plug portion has a slit extending through it. The septum can transition from a non-collapsed state to a collapsed state. When the septum is in a non-collapsed state, the plug portion is offset from the tube portion such that some of the length of the slit extends outward from the distal end of the tube portion. When the septum transitions to the collapsed state, the plug portion is moved inward into the internal cavity such that some of the length of the slit may or may not extend outward from the distal end of the tube portion.
Patent MX-369586-B (MX)
Title: Resin composition.
Inventor: KAZUYA GOSHIMA
IPC: C08J5/00
Filed: 2013-03-15
Abstract: The purpose of the present invention is to provide a resin composition which contains an aromatic polyester resin and has high hydrolysis resistance and high moldability at the same time. The present invention is a resin composition which contains: an aromatic polyester resin that has a terminal carboxyl group concentration of 30 equivalents/ton or less (component (A)); a cyclic carbodiimide compound that has at least two carbodiimide rings that have only one carbodiimide group in each ring (component (B)); and a polyvalent hydroxyl group-containing compound that has a hydroxyl number of 200 or more (component (C)).
Patent MX-346781-B (MX)
Title: Autonomous vehicle modes.
Inventor: ATTARD CHRISTOPHER
IPC: B60W40/09
Filed: 2014-11-20
Abstract: A vehicle operator is identified. Based at least in part on the operator's identity, one or more parameters are determined specifying a mode for autonomously operating the vehicle. The vehicle is autonomously operated at least in part according to the one or more parameters.
Patent MX-354525-B (MX)
Title: Insulating composites for power transmission and distribution.
Inventor: YI ZHANG
IPC: C08K3/40
Filed: 2012-06-26
Abstract: An insulating composite for powder transmission and distribution containing a continuous reinforcing fiber embedded in a thermoset resin, wherein the thermoset resin is a reaction product of a curable epoxy resin composition comprising (a) at least one bisphenol A- type epoxy resin, (b) at least one oxazolidone ring containing epoxy resin, and (c) at least one anhydride hardener and wherein the curable epoxy resin composition has a viscosity of 6,000 millipascals.second or less at 25°C; and a process for preparing the insulating composite.
Patent MX-349270-B (MX)
Title: Liquid hardeners for hardening epoxide resins (ii).
Inventor: HANS-PETER KRIMMER
IPC: C08K5/5475
Filed: 2013-07-31
Abstract: The present invention relates to novel liquid hardeners for hardening hardenable polymer resins, particularly epoxide resins, and epoxide resin compositions and to the use thereof for producing composite fibre materials.
Patent MX-358406-B (MX)
Title: Process of controlled chemical reaction of a solid filler material surface and additives to produce a surface treated filler material product.
Inventor: BURI MATTHIAS
IPC: C09C1/02
Filed: 2013-10-10
Abstract: The present invention relates to a process for preparing a surface treated filler material product with succinic anhydride(s), a surface treated filler material product, a polymer composition, a fiber and/or filament and/or film and/or thread comprising the surface treated filler material product and/or the polymer composition, an article comprising the surface treated filler material product and/or the polymer composition and/or the fiber and/or filament and/or film and/or thread as well as the use of a mono-substituted succinic anhydride for decreasing the hydrophilicity of a calcium carbonate-containing filler material surface and the use of a surface-treated filler material product for initiating the crosslinking reaction in epoxide resins.
Patent MX-353796-B (MX)
Title: Load beam assembly.
Inventor: KNOX H THOMAS
IPC: B60P7/08
Filed: 2013-10-17
Abstract: An elongate beam assembly for supporting cargo is provided. The beam assembly includes an elongate beam extending between first and second ends, the beam comprising a bottom wall with a downward facing surface and extending across a bottom width. A top wall includes an upwardly facing surface and extends across a top width between right and left edges and opposite right and left side walls extend between the bottom and top walls. The bottom width is smaller than the top width. Each of the right and left edges of the top wall define respective right and left side surfaces. Right and left ribs extend from a bottom edge of each respective right and left side surface to the respective right and left side wall.
Patent MX-358480-B (MX)
Title: Peristaltic pump cassette.
Inventor: JOEL D WIESNER
IPC: A61M5/168
Filed: 2013-09-09
Abstract: A peristaltic pump having a plurality of rollers mounted on a rotor rotatable about an axis of rotation. The pump includes a cassette (5) comprising a flexible stator member (113) with a fixed portion secured to the cassette body, a second portion opposite the fixed portion, a reaction surface and a second surface opposite the reaction surface, the reaction surface being defined between the fixed portion and the second portion. The flexible tube (45) to be squeezed by the rollers is secured to the cassette body, wherein at least a portion of the tube is disposed against the reaction surface.