baber/WOPTO huggingface dataset:
Patent CA-3089092-A1 (CA)
Title: Composes pyrazoliques substitues par un heteroaryle et usage pharmaceutique associe
Inventor: MIURA TOMOYA
IPC: A61K31/506
Filed: 2019-04-03
Abstract: L'invention concerne : un composé pyrazole substitué par hétéroaryle ou un sel pharmaceutiquement acceptable de celui-ci ayant une activité inhibitrice de SGLT1 et une utilité médicinale ; une composition médicinale le comprenant ; et des utilisations médicales du composé, du sel et de la composition. L'invention concerne particulièrement un composé représenté par la formule [X] (dans la formule, R1 représente hydrogène ou halogène, R2 représente un alkyle en C1-6 ou un halo-alkyle en C1-6, le cycle Het est un pyridyle substitué ou un pyrazinyle, pyrimidinyle ou pyridazinyle pouvant être substitué) ou un sel pharmaceutiquement acceptable de celui-ci, une composition médicinale le comprenant, et des utilisations médicales du composé, du sel et de la composition.
Patent CA-3091178-A1 (CA)
Title: Fuel cell system and method for its operation
Inventor: KORSGAARD ANDERS RISUM
IPC: H01M8/0612
Filed: 2019-02-14
Abstract: A fuel cell system (1) comprising a fuel cell (2), a liquid fuel supply (3) for providing liquid fuel, an evaporator (6) for evaporating the liquid fuel to fuel vapor, a reformer (7) for catalytic conversion of the fuel vapor to syngas for the fuel cell and a burner (8) for heating the reformer (7). The burner (8) comprises a catalytic monolith (21) down-stream of a mixing chamber (31) in which air is mixed with evaporated fuel or rest gas prior to entering the monolith (21). The mixing chamber (31) is surrounded by a sleeve (23), which comprises a plurality of openings (29A, 29B) around the mixing chamber (31) for supply of fuel vapor through the openings (29A, 29B) in the startup phase and for supply of rest gas through the openings (29A, 29B) during normal operation. Optionally, a heat exchanger (17) is provided between the burner (8) and the reformer (7) for reducing the temperature of the exhaust gas from the burner (8) before it reaches the reformer (7). This temperature reduction prevents degradation of the reformer (7) by hot exhaust gas during start-up of the fuel cell system (1).
Patent CA-3091595-A1 (CA)
Title: Excavator mounted head and assembly for supporting and angularly adjusting a clamshell style bucket assembly during such as a dredging operation
Inventor: BERGERON RAYMOND E
IPC: E02F3/413
Filed: 2020-08-28
Abstract: A tilt adjustable head attachment assembly for a clamshell style bucket for orienting first and second bucket halves at an angle relative to a length axis extending through an elongated and rigid attachment associated with a piece of power equipment, for supporting and manipulating the bucket. A frame has a three dimensional body, upwardly extending pillar mounts located at upper ends of the body and incorporating support shafts for receiving overlapping hinged locations associated with support arms for each of the first and second clamshell bucket halves. A platen is positioned pivotally arranged between the pillar mounts and includes an upper location engaged by an end projection of the elongated attachment. A cylinder is connected to a fixed underside location of the frame at a first end and to the platen at a second end and, upon being actuated, pivotally displacing the platen to in turn angle the frame and supported clamshell bucket halves relative to the excavator attachment according to a desired orientation.
Patent CA-3093074-A1 (CA)
Title: Procede pour generer de multiples produits cellulaires a partir d'une seule source de cellules pluripotentes
Inventor: ZENG XIANMIN
IPC: C12N5/0735
Filed: 2019-03-11
Abstract: L'invention concerne des procédés pour générer de multiples produits cellulaires par l'intermédiaire de la différenciation de cellules à partir de cellules pluripotentes uniques conformes sur le plan clinique en de multiples produits cellulaires choisis parmi l'épithélium rétinien, des cellules progénitrices rétiniennes, des cellules souches neuronales, des neurones dopaminergiques, des astrocytes, des hépatocytes, des cellules endothéliales et des cellules mésenchymateuses en faisant appel à des protocoles de différenciation standard pour les multiples produits cellulaires.
Patent CA-3093496-A1 (CA)
Title: Signal transmission method, and related device and system
Inventor: WU JI
IPC: H04J3/06
Filed: 2019-01-24
Abstract: A data transmission method, and a device and system related thereto. The method comprises: a network device transmitting a synchronization signal/physical broadcast channel (SS/PBCH) block after a listen before talk (LBT) process, an actual time position at which the SS/PBCH block is transmitted being a preset time position in a synchronization signal burst set window corresponding to the SS/PBCH block, the synchronization signal burst set window comprising a plurality of preset time positions corresponding to each of one or more SS/PBCH blocks. The above solution enables a network device to transmit SS/PBCH blocks at multiple possible positions after an LBT process succeeds, thereby increasing the probability of successfully transmitting the SS/PBCH blocks at preset time positions.
Patent CA-3096145-A1 (CA)
Inventor: CHEN LEI
IPC: G06N20/00
Filed: 2020-10-09
Abstract: Systems and methods of generating interpretive data associated with data sets.  Embodiments of systems may be for adapting Grad-CAM methods for embedding networks. The system includes a processor and a memory. The memory stores processor-executable instructions that, when executed, configure the processor to: obtain a subject data set; generate a feature embedding based on the subject data set; determine an embedding gradient weight based on a prior-trained embedding network and the feature embedding associated with the subject data set, the prior-trained embedding network defined based on a plurality of embedding gradient weights respectively corresponding to a feature map generated based on a plurality of training samples, and wherein the embedding gradient weight is determined based on querying a feature space for the feature embedding associated with the subject data set; and generate signals for communicating interpretive data associated with the embedding gradient weight.
Patent CA-3096756-A1 (CA)
Inventor: FROHLICH JOHANNES MALTA
IPC: B65B31/04
Filed: 2019-05-08
Abstract: The present invention relates to a novel nasal spray containing an aqueous solution or a fluid with an anxiolytic or anticonvulsant substance, wherein the nasal spray is characterized in that with the nasal spray, two sprays with each an equivalent, defined volume of the aqueous solution or liquid of the active agent, can be intranasally administered to a patient and wherein the nasal spray allows for an administration, independent of the spatial orientation of the nasal spray in any position of the patient (standing upright, sitting, lying or in any intermediate position). The nasal spray can be used directly without prior activation. Preferably it is apparent from the nasal spray whether a spray or even a second spray has been made with the nasal spray. Preferably, a spray of the nasal spray can be administered one- handed by the patient or a third person. The active agent in the inventive nasal spray is a benzodiazepine or a GABA-receptor agonist, preferably midazolam or a derivative thereof or a salt of these active agents. The nasal spray according to the present invention may be used for sedation, premedication or treatment of patients with claustrophobia, anxiety disorders or panic attacks or for the treatment of convulsions in CNS diseases, particularly in epileptic seizures or other manifestations of seizures (e.g. febrile convulsions). The invention also relates to a method for hermetically sealing an active agent container for use in supplying an nasal spray in accordance with the invention. The invention also relates to a method of detection by localizing the locally precise administration of an active agent in nasal application, as well as a nasal spray, preferably a bi-dose nasal spray, for which, using the cited method of detection, it has been shown both visually (qualitatively) and quantitatively that an orientation-independent, uniform and locally precise administration of the dose of the active agent onto the nasal mucosa of a patient can be achieved. Also provided is a method for airless and air-tight sealing of an active agent container in accordance with the invention.
Patent CA-3099369-A1 (CA)
Inventor: BELGSIR EL MUSTAPHA
IPC: C08B37/16
Filed: 2019-05-09
Abstract: The present invention relates to a complex of Ag, Zn, Cu, Pt, Au, oxides, hydroxides and salts thereof; with a cyclodextrin of formula (I) as defined in claim 1. Advantageously, the complex further comprises an organic therapeutic agent, preferably an antibiotic agent. The complexation according to the invention advantageously maintains the metal: organic therapeutic agent molar ratio. Even more advantageously, the complexation according to the invention enhances the intrinsic aqueous solubility of the metal-organic therapeutic agent association. The present invention further relates to compositions, pharmaceutical compositions and adequate formulations and uses thereof as well as devices comprising a complex of the invention. Lastly, the invention relates to a method for improving the aqueous solubility of a metal selected from Ag, Zn, Cu, Pt, Au, Ru, As, Sb, Bi, Ti, V, Ni, Hg, Pb, Co, oxides, hydroxides and salts thereof by providing a reaction mixture comprising said metal, an aqueous medium and a cyclodextrin of formula (I) as defined in claim 1.
Patent CA-3099407-A1 (CA)
Title: Coupled downhole shifting and treatment tools and methodology for completion and production operations
Inventor: PETRELLA ALLAN
IPC: E21B34/14
Filed: 2020-11-16
Abstract: ABSTRACT A bottomhole assembly (BHA) located on a conveyance string for actuating downhole tools in a wellbore, such as sleeve valves. The bottomhole assembly has a shifting tool that is capable of being hydraulically actuated independently of a mechanically actuated treatment tool also located on the BHA. The shifting tool has hydraulically actuated shifting dogs for engaging with the sleeve valves, and a shifting-assist mechanism for applying a downhole force on the BHA. The treatment tool is mechanically actuated via manipulation of the conveyance string to isolate the wellbore, for example to treat a formation through an opened sleeve valve.  A  hydraulically cycled flow control valve can be located on the BHA for more convenient control of the fluid flow and pressure in the BHA. The BHA can also have a repositioning mechanism for positioning the shifting tool downhole of an opened sleeve valve without requiring repositioning of the entire BHA.   Date Recue/Date Received 2020-11-16
Patent CA-3102125-A1 (CA)
Inventor: HARRIMAN WILLIAM DON
IPC: A01K67/027
Filed: 2019-06-05
Abstract: La présente invention concerne, entre autres, un poulet transgénique. Dans certains modes de réalisation, le poulet transgénique comprend des cellules B dans lesquelles le locus de chaîne lourde d'immunoglobuline endogène comprend : (a) un gène de chaîne lourde d'immunoglobuline fonctionnelle comprenant un acide nucléique codant pour un domaine variable de chaîne lourde dans lequel le CDR3 est dans la plage allant de 30 à 60 acides aminés en longueur et comprend au moins 2 résidus de cystéine ; et (b) une pluralité de pseudogènes qui sont fonctionnellement liés audit gène de chaîne lourde d'immunoglobuline fonctionnelle et qui donnent, par conversion génique, une séquence de nucléotides à l'acide nucléique codant pour le domaine variable de chaîne lourde de (a), les pseudogènes étant en amont ou en aval du gène de chaîne lourde d'immunoglobuline fonctionnelle.
Patent CA-3102239-A1 (CA)
Inventor: PETKOV JORDAN TODOROV
IPC: C11D1/04
Filed: 2019-04-24
Abstract: L'invention concerne une composition de barre de détergent synthétique comprenant un ester méthylique sulfoné d'un acide gras ayant une longueur de chaîne de 16 à 18 atomes de carbone (C16-C18), l'ester méthylique sulfoné étant présent en une proportion de 5 % à 30 % en poids de la composition ; un co-tensioactif choisi dans le groupe constitué par le sulfosuccinate d'alkyle, le sulfate d'alkyle, le sulfate d'alkyl-éther, le polyglucoside d'alkyle, ou la combinaison de ceux-ci ; un alcool gras choisi dans le groupe constitué par l'alcool cétylique, l'alcool stéarylique ou l'alcool cétostéarylique ; un acide gras saturé ; une charge ; et un humectant/hydratant. La composition de barre de détergent synthétique est utile en tant que barre d'hygiène personnelle, de nettoyage du linge ou de la vaisselle.
Patent CA-3103217-A1 (CA)
Title: Plastic scrubber for paint spray booth
Inventor: SALAZAR ABRAHAM J
IPC: B01D47/06
Filed: 2020-12-18
Abstract: , ABSTRACT A wet scrubber having a body that is molded from a plastic material in combination with a nozzle insert that is removably received in the inlet of the wet scrubber and configured to optimize the speed of fluid flow entering a mixing chamber provided in the wet scrubber. Interchangeable nozzle inserts allow to optimize operation of the wet scrubber for different processes the wet scrubber is operating in conjunction with. CA 3103217 2020-12-18
Patent CA-3103642-A1 (CA)
Inventor: NAKAMURA ATSUYA
IPC: A61K47/26
Filed: 2019-06-11
Abstract: Provided is a composition including delamanid particles for which the formation of secondary particles is suppressed. Specifically, provided is a composition including (A) delamanid particles and (B) a surface stabilizer.
Patent CA-3104304-A1 (CA)
Inventor: AHER ANKUR ANIL
IPC: G06F17/00
Filed: 2020-12-24
Abstract: Systems and methods are described herein to search for content recommendations, and in particular, for generating emoji-based metadata for content and processing an emoji-based query using the emoji-based metadata. A system identifies a content item posted via one or more social platforms. A system may retrieve a quantity of instances of a reaction to the content item. The reaction may correspond to an emoji. A  system may retrieve a comment posted in association with the content item via the one or more social platforms. A system may map the comment to the emoji based on a rule. The system may generate a factor associated with the content item and the emoji based on the quantity of instances of the reaction and based on the mapping of the comment to the emoji. The system stores the factor in a database in association with an identifier of the content item to facilitate processing of an emoji-based query.
Patent CA-3106552-A1 (CA)
Title: Active fiber package
Inventor: HOVHANNISYAN GRIGOR
IPC: H01S3/067
Filed: 2019-07-04
Abstract: The present invention provides an active fiber package for use in a fiber laser, amplifier, or ASE source comprising: a plate-shape base comprising a groove having a configuration of at least two spirals for receiving and fixedly holding an active fiber therein, said at least two spirals are coplanar enabling visibility of said active fiber, the outer loop of one spiral transitioning smoothly to the outer loop of another spiral, and the inner loop of each one of said spirals transitioning smoothly into a relatively short straight section; wherein a portion of said straight section of one of said spirals spliced to a coupling fiber, and wherein multiple inner loops of each one of said spirals in proximity to said straight section having a relatively low radius of curvature for enabling tight coiling of said active fiber, thus, for reducing thermal modal instability (TMI) and increasing lasing power.
Patent CA-3107410-A1 (CA)
Inventor: CORNELL ROBERT J
IPC: A61F2/26
Filed: 2019-07-22
Abstract: L'invention concerne des implants qui facilitent l'expansion tissulaire tout en n'inhibant pas sensiblement le mouvement anatomique normal. Les implants peuvent être faits de matériaux différents ou fabriqués selon différentes configurations de telle sorte qu'une propriété mesurée à un premier emplacement sur ledit implant est différente de ladite même propriété mesurée à un second emplacement sur ledit implant. Dans un mode de réalisation particulier, les implants peuvent être un implant pénien cosmétique.
Patent CA-3112333-A1 (CA)
Inventor: LEBEL PAUL M
IPC: C12Q1/00
Filed: 2019-09-13
Abstract: Disclosed herein is a method for assaying binding affinity between a first molecule and a second molecule in a micro-fluidic device. The micro-fluidic device comprises a flow region and a chamber that opens off of the flow region. In some embodiments, the methods comprise: providing the second molecule into the chamber, wherein the second molecule is labeled with a signal-emitting moiety and a first capture micro-object comprising the first molecule is present in the chamber; removing unbound second molecule from the microfluidic device; providing a second capture micro-object into the chamber, wherein the second capture micro-object comprises a third molecule which specifically binds to the second molecule; detecting over a period of time a decrease in an amount of second molecule bound to the first capture micro-object; and determining a relative binding affinity between the first molecule and the second molecule.
Patent CA-3113562-A1 (CA)
Inventor: GUILLONNEAU CAROLE
IPC: C07K16/18
Filed: 2019-09-20
Abstract: The present invention relates to isolated anti-human CD45RC antibodies or binding fragments thereof, to nucleic acids and expression vector encoding the same, to compositions comprising the same, and to uses thereof as medicaments, including for the prevention and/or treatment of CD45RChigh-related diseases (including autoimmune diseases, undesired immune responses, monogenic diseases, and lymphoma or cancer), in particular for use in preventing and/or treating graft-versus-host disease (GVHD).
Patent CA-3113863-A1 (CA)
Inventor: CLOUPET ANN
IPC: F23C99/00
Filed: 2019-12-10
Abstract: The present invention concerns a combustion reactor (300) for chemical looping combustion (CLC) configured to operate in a fluidised bed, comprising: a lower chamber (320) forming a first reaction zone for the combustion of a hydrocarbon feedstock in the presence of particles of an oxidation-reduction active mass, comprising a first side wall and being configured to include a dense fluidised bed; an elongate upper chamber (340) with smaller passage cross-section than that of the lower chamber, forming a second reaction zone for the combustion of gaseous effluents originating from the combustion in the lower portion, comprising a second side wall and being configured to include a dilute fluidised bed; an intermediate portion (330) connecting the two chambers, and including an inner wall forming a right angle with the side walls of the two chambers. The invention also relates to the facility and the CLC process incorporating such a reactor (300).
Patent CA-3115714-A1 (CA)
Inventor: ARGENTO CLAUDIO
IPC: A61M25/00
Filed: 2019-10-18
Abstract: Medical devices that can be delivered in a first, flexible configuration and subsequently locked into a second, rigid configuration are provided. The device comprises an elongate body having a plurality of slots openings along a bending portion of the body. Using a tension member to shorten the distance between two points along the elongate body causes the device to curve. The device can be locked into the curved configuration.
Patent CA-3121512-A1 (CA)
Title: Collection device for meter calibration of air seeder tanks
Inventor: MARTENS WILHELM
IPC: A01C7/08
Filed: 2021-06-08
Abstract: A collection device has a chute supported below the calibration opening on pneumatic delivery lines through which seed can be dispensed during calibration of a seed meter below a seed tank of an agricultural air seeder implement. The chute has a top opening at a top side in alignment with the calibration opening thereabove so as to receive seed discharged through the calibration opening into the chute through the top opening and a bottom that slopes downwardly to one end locating a discharge opening through which collected seed is dispensed. The chute is supported on bag mounts of the implement from which a flexible calibration bag is otherwise suspended.  A gate is operably associated with the discharge opening.
Patent CA-3126375-A1 (CA)
Inventor: FERRARA ARTURO
IPC: A63J19/00
Filed: 2020-01-17
Abstract: La présente invention concerne un théatre de marionnettes portable (1), comprenant une paire de parois latérales (2) et une paroi avant (3) ayant une ouverture centrale (4) qui est conçue pour faire face au public, une pluralité de parois internes (5) définissant un ou plusieurs décors (5A) et un rideau (5B), un élément de couverture (6), qui est adapté pour recouvrir les parois latérales (2) et la paroi avant (3). Les parois latérales (2) et la paroi avant (3) sont sensiblement verticales et conjointement articulées pour former une structure pliable (7) qui est adaptée pour alterner entre une configuration repliée avec les parois (2, 3) dans une relation de chevauchement mutuel, et une configuration verticale avec les parois (2, 3) à angle droit et sensiblement verticales, et inversement. L'élément de couverture (6) est sous la forme d'un couvercle, avec une partie centrale plate (13) et des bords repliés vers le haut (14) pour recevoir dans celle-ci les parois internes (5) et la structure pliable (7) dans la configuration repliée. L'élément de couverture (6) est adapté pour être retourné avec les bords pliés (14) faisant face vers le bas et en contact avec les parois latérales (2) et la paroi avant (3) dans la configuration verticale. En outre, la partie centrale plate (13) de l'élément de couverture (6) comporte une pluralité de fentes (15) pour permettre que les parois internes (5) soient introduite de façon amovible dans celles-ci du sommet supérieure à des positions faisant face à l'ouverture centrale (4).
Patent CA-3126837-A1 (CA)
Inventor: ALTSHULER GREGORY
IPC: A61B1/002
Filed: 2020-01-20
Abstract: L'invention concerne un instrument pour des applications endoscopiques, y compris l'urologie. L'instrument peut comprendre à la fois des canaux d'irrigation et d'aspiration, une attraction et une aspiration efficaces de fragments de tissu et de calcul, une clarté de visualisation améliorée de la zone d'intervention, des fibres d'éclairage ayant une fonction de guidage pour une version souple d'endoscopes. Dans certains modes de réalisation, une tête distale est conçue pour localiser l'embouchure du canal de travail à dans un angle de visée du système de visualisation. Dans certains modes de réalisation, un capuchon transparent est disposé à l'extrémité distale de l'endoscope pour fournir une vue améliorée de la zone d'intervention. Les canaux d'Irrigation et d'aspiration peuvent être agencés de telle sorte qu'un écoulement d'eau constant va attirer les particules de tissu et de calcul et éliminer le liquide chauffé. Les fibres d'éclairage peuvent être utilisées comme des liaisons de traction ou des liaisons pousser-tirer pour dévier et guider les versions souples d'endoscope.
Patent CA-3128024-A1 (CA)
Title: Chemical compounds
Inventor: SPEAKE JASON D
IPC: A61K31/4985
Filed: 2020-01-29
Abstract: The present disclosure describes novel compounds, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. The compounds of the disclosure have activity as prostaglandin EP4 receptor antagonists, and are useful in the treatment or alleviation of pain and inflammation and other inflammation-associated disorders, such as arthritis, treating or preventing disorders or medical conditions selected from pain, inflammatory diseases and the like. Also described herein are methods of treating pain by administering the compounds of the disclosure, which are EP4 receptor antagonists.
Patent CA-3128772-A1 (CA)
Title: Post anchor
Inventor: MILANOWSKI DANIEL JAMES
IPC: E04H17/22
Filed: 2021-08-23
Abstract: A post anchor for a railing system or a fencing system. The post anchor has a base plate and a collar, where the collar extends from the base plate. The collar defines an interior capable of receiving a post. The post anchor can be unitarily formed. A drainage system can be included in the post anchor.