baber/WOPTO huggingface dataset:
Patent NZ-243567-A (NZ)
Title: Pharmaceutical oral formulation of a dideoxy purine nucleoside comprising the nucleoside together with a water-insoluble antacid buffering composition
Inventor: ISMAT ULLAH
IPC: A61K9/14
Filed: 1992-07-15
Abstract: Improved oral dosage formulations for acid-labile dideoxy purine nucleoside derivatives such as ddA, ddI, and ddG, have been developed by incorporating selected water-insoluble buffering systems in the formulation. These novel formulations provide reduced mass dosage units in the form of convenient, palatable chewable/ dispersible tablets or a dry powder sachet. The reduced mass requirement, necessary to allow tablets of reasonable size, was achieved in part by an unexpected 20 to 25% increase in drug bioavailability resulting from use of the selected buffering systems comprised of an insoluble magnesium antacid agent and either dihydroxyaluminum sodium carbonate or calcium carbonate.
Patent NZ-250663-A (NZ)
Title: Conveyor for tablet tray: pins engage tray and move one space horizontally during tray loading process
Inventor: BERTA NORBERT I
IPC: A23G7/00
Filed: 1994-01-11
Abstract: Methods and apparatus for applying coating to products such as medicaments are disclosed. The present invention provides apparatus and methods for controlling the loading and feeding of tablets onto carrier plates (50) for transfer to various processing stations of the coating system. A novel plate indexing apparatus (300) includes a box cam follower device (314) mounted to an engagement bar (302) for incrementally advancing the plates in a precisely controlled manner. A second complementary shaped engagement bar (320) provides a locking mechanism to ensure the plates are always under positive control. In one embodiment the plate indexing apparatus also controls the feeding of the tablets. An alternative embodiment includes a vacuum pick-up system for feeding tablets onto the carrier plates as the plates are incrementally advanced.
Patent NZ-270023-A (NZ)
Title: Sprayable fireproofing compositions comprising cementitious binder and a hydration water-containing aggregate; method of fireproofing steel substrates
Inventor: BERNEBURG PHILIP J
IPC: C04B35/66
Filed: 1994-11-29
Abstract: Sprayable fireproofing compositions for structural members such as steel columns are provided. The compositions comprise a cementitious binder such as Portland cement, and a hard aggregate containing water of hydration. Such hard aggregates contribute not only to the strength of the fireproofing composition, but also contribute thermally. The product is produced by dry blending a mixture of the cementitious binder and hard aggregate, as well as other-optional additives. Upon the addition of water, sprayable slurries are formed which can be pumped to the point of application. An accelerator is added in close proximity to the point of injection. Other additives may also be included, such as starch, adhesives and cement strength enhancers. The slurries adhere to the structural member in the slurried state and after setting to provide excellent fire and heat protection.
Patent NZ-272813-A (NZ)
Title: Preparation of mono- and dicarboxylic acids through the oxidation of unsaturated fatty acids
Inventor: SANTOS EMMANUEL DOS
IPC: B01J27/19
Filed: 1995-08-18
Abstract: Prepn. of mono- and di-carboxylic acids from unsatd. fatty acids and/or derivs., comprises: (i) oxidising an unsatd. fatty acid, in the form of an acid and/or ester, with hydrogen peroxide in presence of a metal oxide or a carboxylic acid, opt. with a ruthenium catalyst; (ii) reacting the mixt. with nitric acid in presence of a vanadium catalyst, opt. with a co-catalyst; and (iii) recovering the mono- and di-carboxylic acids. The starting material is pref. a fatty acid with at least one double bond, an animal fat or oil, a vegetable oil, an ester of a pptd. fatty acid and is pref. oleic, colza, sunflower and soya oil. The ruthenium catalyst is pref. present in amt. of 1-35 % w.r.t. H2O2. H2O2 may be used with a gp. VIa metal catalyst, esp. a W and/or Mo catalyst in amt. of 1-35 (pref. 3-10) %, w.r.t. H2O2. The vanadium catalyst may be a V halide, a V oxide, a V oxyhalide, a V or vanadyl sulphate, an alkali metal or ammonium vanadate, or V acetylacetonate. The optional V co-catalyst may be based on a Gp. VIIa or VIII metal. A stoichiometric amt. of H2O2 or a 0-50 % excess is used with a carboxylic acid in a hydrogen peroxide : carboxylic acid molar ratio of 10-500 (pref. 10-40) %.
Patent NZ-294918-A (NZ)
Title: Substituted pyridazino quinoline derivatives and medicaments
Inventor: BARE THOMAS MICHAEL
IPC: A61P25/08
Filed: 1995-11-08
Abstract: The invention relates to pyridazinoquinoline coumpounds of formulae A and A', wherein: ring A is chosen from an ortho fused aromatic or heteroaromatic five- or six-membered ring; R<4> is selected from the group consisting of halo, (1-4C)alkyl, NO2, CN, (C1-3)perfluoroalkyl, OH, OCF3, (2-4C)alkenyl, (2-4C)alkynyl, O(1-4C)alkyl, NR'R", SO2NR'R", or SOmR'; R<1> is selected from H, (1-6C)alkyl, or -(CH2)nL; R<2> is selected from H or -(CH2)nL; L is a variety of substituents including phenyl, heterocyclic groups and heteroaryl; n is 0-6; m is 0-2, R<5> is selected from H, (1-6C)alkyl or (1-6C)alkylaryl; R<3> is selected from H or -(CO)R<6> wherein R<6> is selected from a variety of substituents including hydrogen, (1-12C)alkyl, pyridyl, phenyl, pyridyl (1-12C)alkyl and phenyl (1-4C)alkyl; and R' and R" are selected from H, (1-4C)alkyl, (3-6C)cycloalkyl, phenyl (0-4)alkyl-, heterocycle (0-4C)alkyl- or heteroaryl (0-4C)alkyl- to pharmaceutical compositions containing them and to methods for the treatment of neurological disorders utilizing them.
Patent NZ-332540-A (NZ)
Title: Vehicle arresting bed with layer over bed sufficient to support pedestrian
Inventor: ANGLEY RICHARD D
IPC: B64F1/00
Filed: 1998-02-06
Abstract: The vehicle arresting bed, for installation at the ends of aircraft runways, is stated to be effective to safely decelerate aircraft entering the bed. The arresting bed is assembled of a large number of blocks of cellular concrete (70) having predetermined compressive gradient strength, so that aircraft landing gear is subjected to drag forces effective to slow a variety of types of aircraft, while providing deceleration within a safe range of values. The bed typically includes an entry region (52) of a depth increasing from 9 to 24 inches formed of blocks having a first compressive gradient strength. A second region (54), which may be tapered into the first region and increase in depth to 30 inches, is formed of blocks having a greater compressive gradient strength. An aircraft thus experiences increasing drag forces while it travels through the bed, to provide an arresting capability suitable for a variety of aircraft. A protective "hardcoat" layer (62) of cellular concrete of strength greater than the blocks overlays the blocks to enable service personnel to walk on the bed without damage. Arresting bed systems may be provided in alternative configurations, such as a bed formed of an aggregate including pieces of cellular concrete with or without interspersed pieces of other compressible material and covered by a "hardcoat" layer.
Patent NZ-333071-A (NZ)
Title: Method for cleaning apparatus such as filters used during foodstuff production using a combination of a cyclic nitroxyl compound and a hypohalite compound
Inventor: MOL MARTINUS NICOLAAS MARIA
IPC: C11D7/54
Filed: 1997-05-26
Abstract: The invention relates to a method for cleaning apparatus used during the production of foodstuffs, more in particular the filtration thereof, wherein this apparatus is contacted after use with a cleaning system based on the combination of a cyclic nitroxyl compound and a hypohalite.
Patent NZ-334630-A (NZ)
Title: Board game simulating mountain climbing
Inventor: SOLE TIMOTHY CHARLES
IPC: A63F3/04
Filed: 1999-03-11
Abstract: A board game representing mountain climbing includes two or more separate paths, one path for each player to follow.  Four paths are shown on the board illustrated.  Each player has a playing token, and a "back-up" playing token. Movements of the playing tokens are determined by use of a "random event generator" and a random number generator. The number shown by the random number generator determines the number of spaces that one or both tokens are moved, while the random event generator determines which of the two tokens is moved, and in which direction. Symbols on the board, such as snowflake symbols, represent hazards. If a token lands on a hazard symbol, then a card is drawn from a pack.  The card may contain instructions for an event to occur, or alternatively maybe an "event negating card", that functions like a "get out of jail free card".  If the card suggests that an event is to occur, then the player follows the instructions immediately.  If the card is an "event negating card", the player may retain it for use later.
Patent NZ-335410-A (NZ)
Title: Washer, typically dishwasher, with closure to seal top of retracted sliding chamber in cabinet, with sealing between sliding drawer type container and lid formed by overlapping air hose, with drainage provided between overlapping sections
Inventor: MAUNSELL STEVE
IPC: A47L15/00
Filed: 1998-01-30
Abstract: Gasket 18 is formed from inflatable tubing and is sealed at end 39. In an overlapped region slots 42 are provided under gasket 18 to drain fluid back into the wash chamber (not shown).
Patent NZ-335992-A (NZ)
Title: Substituted pyrimidinone and pyridone compounds and methods of use
Inventor: SPOHR ULRIKE D
IPC: C07D405/00
Filed: 1997-12-04
Abstract: Substituted pyrimidinone and pyridone compounds of formula (I)are effective for prophylaxis and treatment of TNF-á, IL-â, IL-6 and/or IL-8 mediated disease, pain and diabetes.  Also disclosed are processes for making such compounds as well as intermediates useful in the processes.
Patent NZ-337615-A (NZ)
Title: Processing of vegetable biomass in screw press with axially separated chambers
Inventor: HANSEN GRAEME
IPC: A23K10/10
Filed: 1998-03-09
Abstract: Biomass from an agricultural crop in a naturally damped state is crushed in screw presses for further processing. After pressing to separate a low-solid phase, the remaining high-solid phase is processed with pressurized vapor. Expansion occurs, a vapor phase is separated and the high-solid phase is cooled, wherein substances are decomposed under the influence of enzymes and/or fermentation with microorganisms, while a gaseous phase is separated. A low-solid and a high-solid phase is separated in the remaining mixture. All separated phases are used to obtain preferably ethanol, protein concentrate and fibers or are reprocessed. A screw press (200) enabling continuous implementation of said method comprises axially disposed inline chamber areas (201...204) with a common integral shaft (205) and screws (206...211) arranged thereon. Said chambers are tightly sealed off from each other by compacted material plugs. The aqueous liquid phase is reprocessed (215...217) in the opposite direction to said material. An additional chamber area (218) having its own screw can connect two partial areas (203...204) to each other, thereby forming a loop with the advancing material.
Patent NZ-503141-A (NZ)
Title: A cabinet, parts thereof and associated methods
Inventor: VAUGHAN STEWART
IPC: B29C53/84
Filed: 1998-09-09
Abstract: A cabinet for a refrigerator is formed from a twin sheet thermoformed panel divided into a plurality of wall sections (8, 9, 10) by seams (6) where the twin sheets (2, 3) contact. The panel is folded to form the rear (10) and two sidewalls (8, 9) of a refrigerator cabinet, and top end cap and a base plinth are fitted to retain the walls in position. Refrigeration system components are carried on the base plinth. The walls (8, 9) and back (10) are secured by having their upper and lower edges (25, 30) fitted within peripheral channels (28, 29) on the top end cap (20) and the base plinth (21). Additionally they may be further secured by fusing contacting portions (65, 76) of the inner sheet of the panel in the region adjacent folded seams (6). The panel is preferably filled with rigid insulating foam while still supported on the thermoforming mould. The seams (6) are preferably provided on the back face (61) of the cabinet, spaced from the corners between side and rear faces, providing improved aesthetics with the fold lines hidden. An improved heater for softening seams between wall sections is disclosed.
Patent NZ-503719-A (NZ)
Title: Multimeric apolipoprotein A-I (ApoA-I) agonist compounds and their use to treat dyslipidemic disorders and prevent toxic shock
Inventor: SEKUL RENATE
IPC: A61P31/04
Filed: 1998-09-28
Abstract: Peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I are described.  The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia and toxic shock.
Patent NZ-506579-A (NZ)
Title: Palatable oral liquid formulations of benzoxazinones hiv reverse transcriptase inhibitors
Inventor: BAHAL SURENDRA M
IPC: A61K31/538
Filed: 1999-02-17
Abstract: A liquid pharmaceutical composition for oral administration comprising from 0.1 to 15% by weight of a benzoxazinone HIV reverse transcriptase inhibitor agent such as (-) 6-chloro-4 cyclopropyl-ethynyl-4-trifluoromethyl-1, 4 dihydro-2H-3, 1-Benzoxazin-2-one and from 50 to 90% by weight of a liquid vehicle comprising pylol esters of medium chain fatty acids such as C8 and C10 fatty acid triglycerides. Other formulating agents such as sweetening agents, lecithin suspending agents, etc. may be optionally added.
Patent NZ-512366-A (NZ)
Title: Improved methods for processing activated protein C, a lyophilized pharmaceutical formulation containing activated protein C
Inventor: BAKER JEFFREY CLAYTON
IPC: A61K38/48
Filed: 1998-04-24
Abstract: A lyophilized pharmaceutical formulation comprising activated protein C, which is a serine protease, the formulation not containing the addition of a denaturing agent, urea, histidine, lysine or albumin. The formulation may further comprise a bulking agent such as sucrose, trehalose and raffinose and a buffer such as tris-acetate, sodium citrate and sodium phosphate. When constituted the formulation has a pH of 5.5 to 6.3.
Patent NZ-518619-A (NZ)
Title: Fuel cell adapter system for combustion tools
Inventor: SHKOLNIKOV YURY
IPC: B25C1/06
Filed: 2001-10-10
Abstract: A combustion tool comprising a housing enclosing a fuel metering valve, a fuel cell provided with an adapter and configured for being accommodated in the housing in fluid communication with the fuel metering valve, and a latch (60) disposed in the housing for releasably securing the adapter in fluid communication with the fuel metering valve.  The latch (60) includes a latch body (62) having at least one locking tang (64) movable between a closed position (I) and an open position (II), and a releasable member (70) for moving the locking tang(s) (64) to release the engagement with the adapter, permitting the withdrawal of the fuel cell from the tool.
Patent NZ-520200-A (NZ)
Title: Polynucleotides encoding the Clamydia pneumoniae polypeptides omp P6 precursor gene product
Inventor: MURDIN ANDREW D
IPC: A61K48/00
Filed: 2000-12-20
Abstract: A vaccine against diseases caused by infection by a strain of Chlamydia, specifically Chlamydia pneumoniae, is described. The vaccine comprises vector containing a nucleotide sequence encoding an omp P6 precursor of a strain of C. pneumoniae and a viral promoter to affect expression of the omp P6 precursor in the host, including a human host.
Patent NZ-523408-A (NZ)
Title: Human papilloma virus treatment
Inventor: NEEFE JOHN
IPC: A61K48/00
Filed: 2001-06-26
Abstract: Disclosed is the use of a composition containing (1) a heat shock protein or an immunostimulatory fragment thereof, and (2) a protein of a human papilloma virus or an antigenic fragment thereof in the manufacture of a medicament to treat human papilloma virus infection, including recurrent respitory papillomatosis, in a subject infected or suspected of being infected with a human papilloma virus. Also disclosed is a method of treating a human papilloma virus infection in a subject infected or suspected of being infected with a human papilloma virus of a first type by administering to the subject a composition containing (1) a heat shock protein or an antigenic fragment thereof, and (2) a protein of a human papilloma virus of a second type or an antigenic fragment thereof, where the first type and second type are different.
Patent NZ-526061-A (NZ)
Title: Hair straightening device
Inventor: TOBIN RICHARD NEIL
IPC: A45D20/50
Filed: 2001-12-27
Abstract: A hair straightener or straightening device is provided, that includes a handle (70) adapted to be attached to a housing (50). The housing (50) has a heat transmissive plate (56) surrounded by a cover (60) formed by curved rings (61) and teeth (62), which serve to guide and tension the hair along the heat transmissive plate (56). The transmissive plate (56) is heated by hot air. The air is directed and diverted to heat the transmissive plate (56) to a temperature hot enough to straighten hair.
Patent NZ-531401-A (NZ)
Title: Compositions for increasing cholesterol efflux and raising HDL using ATP binding cassette transporter protein ABC1
Inventor: LAWN RICHARD M
IPC: A61K31/07
Filed: 2000-06-16
Abstract: An isolated polynucleotide has the sequence identified in SEQ ID NO:3 corresponding to the 5' flanking region of the ABC1 gene. Also described are vectors, compositions and host cells comprising the sequence. (62) Divided out of 516061
Patent NZ-533188-A (NZ)
Title: Prodrugs to D-prolines
Inventor: HUWYLER JOERG
IPC: A61P25/28
Filed: 2002-12-06
Abstract: Disclosed are compounds of the formulae (I) and (IA); wherein R1 and R2 are independently selected from each other from the group comprising lower alkoxy, lower alkenyloxy, hydroxy, -OCH(CH3)OC(O)-lower alkyl or -OCH2C(O)N(R3)(R4), with the proviso that only one of R1 and R2 may be hydroxy; R3 and R4 are independently selected from each other from the group comprising hydrogen, lower alkyl, lower alkenyl and cycloalkyl; or R1 and R2 form together with the carbon atom to which they are attached the linking group X, wherein X is -O(CH2)nCH=CH(CH2)nO- or -O(CH2)mO-; n is 1, 2 or 3; and m is 4-8. Further disclosed is the use of compounds of formulae (I) and (IA) in the preparation of medicaments for the treatment of diseases related to all forms of central and systemic amyloidosis.
Patent NZ-539139-A (NZ)
Title: Methods and compositions for providing glutamine
Inventor: BAXTER JEFFREY H
IPC: A23L33/00
Filed: 2002-10-08
Abstract: Disclosed is a use of a nutritional liquid comprising N-acetyl-L-glutamine or a nutritionally acceptable salt thereof selected from lithium, sodium, potassium, calcium, magnesium, quaternary ammonia cations and amine cations as the sole source of glutamine for manufacturing a medicament for use in providing glutamine supplementation for treating a critical illness or injury characterized by insufficient glutamine production to meet the body's needs.
Patent NZ-540620-A (NZ)
Title: Stabilized immunogenic HBc chimer particles
Inventor: LYONS KATELYNNE
IPC: C07K14/02
Filed: 2003-12-10
Abstract: Disclosed is a recombinant chimer hepatitis B core (HBc) protein molecule up to about 600 amino acid residues in length that (a) contains an HBc sequence of at least about 125 of the N-terminal 183 amino acid residues of the HBc molecule that includes the HBc sequence of residue positions 4 through about 75 and about 85 through about 140 in which one or both cysteine residues at positions 48 and 107 is replaced by another residue, and in which the cysteine at residue position 61 is present; (b) contains a peptide-bonded heterologous amino acid residue sequence at one or more of the N-terminus, in the HBc immunodominant loop between residue positions about 76 through about 85 or the C-terminus of the chimer, and wherein (i) zero to all residues in a sequence in said HBc immunodominant loop are present or replaced and said heterologous amino acid residue sequence comprises one to about 245 amino acid residues that constitute an Immunogen or a sequence of 1 to about 40 residues that constitutes an anti-antigen or a chemically-reactive linker residue for a conjugated hapten; or (ii) the sequence of HBc at positions 76 through 85 is present and free from deletions and heterologous residues; or (iii) one or more of residues 76 through 85 is absent or replaced; (c) contains one or both of (i) one to three cysteine residues at an amino acid position of the chimer molecule corresponding to amino acid position -20 to about +1 from the N-terminus of the HBc sequence of SEQ ID NO:1 [N-terminal cysteine residue(s)] in a sequence other than that of the HBc precore sequence and (ii) one to three cysteine residues toward the C-terminus of the chimer molecule [C-terminal cysteine residue(s)]; said chimer molecule (i) containing up to about 5 percent substituted amino acid residues in the HBc sequence relative to SEQ ID NO:1, and (ii) self-assembling into particles that exhibit a ration of absorbance at 280 nm to 260 nm of about 0.9 to about 1.7 after expression.
Patent NZ-540779-A (NZ)
Title: Compositions and methods for siRNA inhibition of HIF-1 alpha
Inventor: REICH SAMUEL JOTHAM
IPC: A61K38/00
Filed: 2003-10-31
Abstract: RNA interference using small interfering RNAs which target HIF-1 alpha mRNA inhibit expression of the HIF-1 alpha gene. As HIF-1 alpha is a transcriptional regulator of VEGF, expression of VEGF is also inhibited. Control of VEGF production through siRNA-mediated down-regulation of HIF-1 alpha can be used to inhibit angiogenesis, in particularly in diseases such as diabetic retinopathy, age related macular degeneration and many types of cancer.
Patent NZ-541282-A (NZ)
Title: Therapeutic formulations for the treatment of beta-amyloid related diseases
Inventor: GERVAIS FRANCINE
IPC: A61K38/08
Filed: 2003-12-24
Abstract: Disclosed is a combination of 3-aminopropanesulfonic acid or sodium 3-aminopropanesulfonate or pharmaceutically acceptable salts thereof with a second agent selected from cholinesterase inhibitors and NMDA receptor antagonists. The combination is useful for the treatment of an amyloid-beta related disease or condition.
Patent NZ-543700-A (NZ)
Title: 7-Azaindoles and use thereof as therapeutic agents
Inventor: HOFGEN NORBERT
IPC: C07D471/04
Filed: 2004-04-23
Abstract: The disclosure relates to substituted 7-azaindoles of formula (I), a method for the production thereof, pharmaceutical preparations comprising said compounds and the pharmaceutical use of said compounds which are inhibitors of phosphodiesterase 4, as active substances in the treatment of diseases which can be influenced by said compounds of formula (I) by means of an inhibition of phosphodiesterase 4-activity, especially in immunocompetent cells (for example, macrophages and lymphocytes).
Patent NZ-549836-A (NZ)
Title: Patient transfer device having inclined upper surface
Inventor: WEEDLING ROBERT E
IPC: A47C27/08
Filed: 2005-02-24
Abstract: A patient transfer device includes a top sheet inclined in a head end portion such that a patient's torso is elevated with respect to the feet. The mattress may include relatively narrow chambers in an intermediate portion for increased strength and stability. The mattress may also include a leg separator in a foot end portion, preferably tapered and including one or more inflatable chambers. The mattress may also include a pump mounted directly to the mattress. The transfer device may include a torso and head support accessory having independently inflatable torso and head chambers and inlet and exhaust tubes connected to each chamber. A distribution manifold includes valves connected to each of the inlet and exhaust tubes for controlled inflation and deflation of the chambers. The device may include a control unit connected to the manifold and mountable to an intubation tube for actuation by a user's thumb.