Patent SG-11201809456U-A (SG)
Title: Interferon beta antibodies and uses thereof
Inventor: GULLA STEFANO
IPC: C07K16/24
Filed: 2017-04-28
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 02 November 2017 (02.11.2017) ill Hu omits Holm o 101101MIR HMV 011 (10) International Publication Number WO 2017/189983 Al WIPO I PCT (51) International Patent Classification: A61K 39/00 (2006.01) C07K 16/24 (2006.01) (21) International Application Number: PCT/US2017/030089 (22) International Filing Date: 28 April 2017 (28.04.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/329,327 29 April 2016 (29.04.2016) US 62/339,709 20 May 2016 (20.05.2016) US 62/483,669 10 April 2017 (10.04.2017) US (71) Applicants: PFIZER INC. [US/US]; 235 East 42nd Street, New York, NY 10017 (US). THE BRIGHAM AND WOMEN'S HOSPITAL, INC. [US/US]; 75 Francis Street, Boston, MA 02115 (US). (72) Inventors: GULLA, Stefano, V.; 345 D. Street, Unit 13, Boston, MA 02127 (US). HUARD, Christine; 58 Cherry Street, #14, Somerville, MA 02144 (US). BUHLMANN, Janet, Elizabeth; 30 Gardner Rd., Apt. 4b, Brookline, MA 02445 (US). ALMAGRO, Juan, Carlos; 320 Con- cord Avenue, Cambridge, MA 02138 (US). KODANGAT- TIL, Sreekumar, R.; 517 Concord Avenue, Lexington, MA 02421 (US). GREENBERG, Steven, A.; 46 New- tonville Avenue, Newton, MA 02458 (US). LAVALLIE, Edward, Roland; 113 Ann Lee Road, Harvard, MA 01451 (US). BENNETT, Eric, M.; 45 Morningside Drive, Ar- lington, MA 02474 (US). MOSYAK, Lidia; 92 Littefield Road, Newton, MA 02469 (US). HALL, James, Perry; 19 Lanes End Road, Stow, MA 01775 (US). COYLE, Antho- ny, John; 12 Union Park, Boston, MA 02118 (US). (74) Agent: MANGASARIAN, Karen et al.; Ropes & Gray Llp, 1211 Avenue Of The Americas, New York, NY 10036 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. 00 00 1-1 (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) with (an) indication(s) in relation to deposited biological material furnished under Rule 13bis separately from the description (Rules 13bis.4(d)(i) and 48.2(a)(viii)) with sequence listing part of description (Rule 5.2(a)) N (54) Title: INTERFERON BETA ANTIBODIES AND USES THEREOF 1-1 0 (57) : The invention relates to antibodies, or antigen-binding fragments thereof, that specifically binds to interferon beta \" (IFNp). Such antibodies, or antigen-binding fragments thereof, are are useful for various therapeutic or diagnostic purposes. C