baber/WOPTO huggingface dataset:
Patent CA-2466806-A1 (CA)
Inventor: SENANAYAKE CHRIS H
IPC: A61K31/4422
Filed: 2002-10-23
Abstract: L'invention se rapporte à des procédés de dissolution d'amlodipine racémique en compositions énantiomériquement enrichies par précipitation avec un acide tartarique en présence d'un solvant non aqueux notamment un N,N'-diméthylacétamide. Le rapport molaire d'acide tartarique d'amlodipine est de préférence inférieur à 0,25:1,0 ou supérieur à 0,75:1,0.
Patent CA-2467336-A1 (CA)
Title: Sieve litter scoop
Inventor: PAIN TAPAS
IPC: A01K1/01
Filed: 2004-05-13
Abstract: The present invention provides an animal refuse scoop comprising a scoop, and a handle attached to the scoop. The scoop defines a top and bottom surface, and a plurality of openings therein. The openings are defined to allow the passage of litter granules therethrough. A cover, having a solid body and a handle attached to the solid body, is pivotably attached to the scoop handle, with the cover solid body being adjacent to the scoop bottom surface. The cover solid body is adapted to matingly cover the scoop openings. A biasing means is attached to the handle, and engages the cover, allowing movement of the cover between a closed position wherein the cover handle is disposed away from the scoop handle and the cover solid body is adjacent to the scoop bottom surface and matingly covering the scoop openings, and an open position wherein the cover is disposed away from the scoop bottom surface and the cover handle is adjacent to the scoop handle. The biasing means biases the cover into the closed position.
Patent CA-2468016-A1 (CA)
Inventor: HUSE WILLIAM D
IPC: C07K16/30
Filed: 2002-11-26
Abstract: The invention provides a grafted antibody, or functional fragment thereof, comprising one or more complementarily determining regions (CDRs) having at least one amino acid substitution in one or more CDRs of a heavy chain CDR, where the grafted antibody or functional fragment thereof has specific binding activity for a cryptic collagen epitope. The invention also provides methods of using an antibody having specific binding activity for a cryptic collagen epitope, including methods of inhibiting angiogenesis, tumor growth, and metastasis.
Patent CA-2470215-A1 (CA)
Inventor: HOME WILLIAM
IPC: F24C7/04
Filed: 2004-06-07
Abstract: A smokeless grilling oven is disclosed. The oven comprises a grate, a frame body, a plurality of infra-red heaters which equals the number of sides of the frame body, and a slanting securing rack for mounting the heaters, wherein the grate is placed onto the frame body and the bottom edge of the frame body suspends the slanting securing rack and the infra-red heaters are mounted onto the slanting securing rack so that the emitting end of the heater is slopingly facing the bottom of the grate.
Patent CA-2471499-A1 (CA)
Inventor: TANAKA GO
IPC: F16F7/09
Filed: 2003-01-15
Abstract: A friction damper (1) includes: a base body (2); a support (4) secured to an elongated member (35) of the base body (2) and having a through hole (3); a rod (7) which extends in such a manner as to pass through the through hole (3) of the support (4) and is movable in an axial direction (X) with respect to the support (4);  a friction member (9) which has a hollow cylindrical portion (8) interposed between the support (4) and a main body portion (85) of the rod (7) in the through hole (3) of the support (4), and which is fixed immovably with respect to the relative movement of the rod (7) in the axial direction (X) with respect to the base body (2); and a tightening means (12) provided for the support (4) so as to tighten the hollow cylindrical portion (8) of the friction member (9) onto the main body portion (85) of the rod (7).
Patent CA-2472860-A1 (CA)
Title: Fuel cell vehicle with single air supply
Inventor: MAKUTA YOHEI
IPC: B62M7/02
Filed: 2004-06-29
Abstract: To provide a fuel cell vehicle capable of efficiently cooling a fuel stack and supplying sufficient reactant gas to the fuel stack with only a single air supply means. Two bypass valves are provided in the blowing passage, and a scavenge gas supply passage for introducing external air into the inside of the fuel cell box as scavenge gas is branched from the upstream bypass valve. The downstream bypass valve contains an electromagnetic three-way valve, and the blowing passage branches into a reactant gas supply passage and a cooling gas supply passage at the downstream bypass valve. The reactant gas supply passage supplies external that is supplied from the blowing passage to the fuel cell stack as reactant gas (oxygen). The cooling gas pipe supplies external air supplied from the blowing passage to the fuel cell stack as cooling gas.
Patent CA-2473464-A1 (CA)
Title: Method to diffract and attenuate an optical signal
Inventor: WICKMAN RANDY
IPC: G02B6/12
Filed: 2003-01-07
Abstract: A method and apparatus are provided for transmitting an optical communications signal. The method includes the steps of disposing a plurality of optical gratings (180) on a surface (166) of an optically transparent substrate, disposing an optical array (144) having a plurality of optical ports (176) adjacent the optically transparent substrate (152) such that an axis of transmission (146) of the optical array passes directly through the substrate, and transmitting a plurality of optical signals of the optical array substantially through the plurality of optical gratings in the substrate.
Patent CA-2473960-A1 (CA)
Inventor: AFONINA IRINA A
IPC: C12Q1/68
Filed: 2002-12-10
Abstract: Oligonucleotide probes/conjugates are provided along with method for their use in assays to monitor amplification wherein the signal produced does not rely on 5' nuclease digestion.
Patent CA-2479266-A1 (CA)
Title: Azetidine derivatives as ccr-3 receptor antagonists
Inventor: WOODS JOHN JAMES
IPC: A61P29/00
Filed: 2003-03-14
Abstract: Compounds of formula (I) in free or salt form, wherein Ar, X, Y, R1, R2, R3, R5, m, n, p, and q have the meanings as indicated in the specification, are useful for treating conditions mediated by CCR3. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are als o described.
Patent CA-2481005-A1 (CA)
Title: Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and radiotherapy
Inventor: GERONI MARIA CRISTINA ROSA
IPC: A61K33/243
Filed: 2003-03-17
Abstract: The present invention provides the use of acryloyl distamycin derivatives, in particular .alpha.-bromo- or .alpha.-chloro-acryloyl distamycin derivatives, in combination with radiotherapy, for the treatment of tumors.
Patent CA-2483517-A1 (CA)
Title: Non-stuttering biofeedback method and apparatus using daf
Inventor: STUART ANDREW
IPC: G09B21/00
Filed: 2003-04-25
Abstract: Methods, devices and systems treat non-stuttering speech and/or language related disorders by administering a delayed auditory feedback signal having a delay of under about 200 ms via a portable device. The DAF treatment may be delivered on a chronic basis. For certain disorders, such as Parkinson's disease, the delay is set to be under about 100 ms, and may be set to be eve n shorter such as about 50 ms or less. Certain methods treat cluttering (an abnormally fast speech rate) by exposing the individual to a DAF signal havi ng a sufficient delay that automatically causes the individual to slow his or h er speech rate.
Patent CA-2485029-A1 (CA)
Inventor: NESS JOHN T
IPC: E05D13/00
Filed: 2004-10-19
Abstract: Apparatus and method for wheel assemblies, specifically directed to precision roller wheel assembly for use with patio doors or the like, that provides a rust-resistant, salt resistant wheel assembly for providing a smooth gliding, quiet operating, easy to adjust, door wheel system that is corrosion free and is believed to be able to withstand hurricane force winds. A precision roller wheel assembly for use on a lower surface of a door, especially a patio door or the like, the assembly comprising a two-piece housing, the two -pieces being a mirror image of each other, for receiving at least one precision machined corrosion resistant sealed roller wheel mounted on an axle, means for mounting the assembly to a patio door or the like, and adjustment means for vertically adjusting the assembly in its position of use.
Patent CA-2486989-A1 (CA)
Title: New compounds useful for the treatment of obesity, type ii diabetes and cns disorders
Inventor: JENMALM-JENSEN ANNIKA
IPC: A61P25/00
Filed: 2003-06-19
Abstract: The present invention relates to compounds of the general formula (I), wherein P is sulfone or sulfonamide; and A, B, W, X, Y and R3 are as defined in the description;to pharmaceutical compositions comprising these compounds, and to the use of the compounds for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes, and/or CNS disorders, to achieve reduction of body weight and of body weight gain.
Patent CA-2487416-A1 (CA)
Title: Methods and compositions for treating and diagnosing diabetes
Inventor: BLUME JOHN E
IPC: G01N33/68
Filed: 2003-06-10
Abstract: The present invention provides polynucleotides encoding potassium channels a s well as methods of using the potassium channels to treat and diagnose diabet es and a predisposion for diabetes.
Patent CA-2487418-A1 (CA)
Inventor: CHONG MATTHEW PAUL CHEN HENG
IPC: A61K38/00
Filed: 2003-06-06
Abstract: The present invention provides inhibitors of metalloprotineases that may be extracted from lactational secretions such as milk and colostrum. The inhibitors have use in the treatment of a range of diseases such as disorders of the gastrointestinal tract, cardiovascular conditions and wound healing.  Methods for purifying the inhibitors are also disclosed.
Patent CA-2490584-A1 (CA)
Title: Method and apparatus for fabrication of polymer-coated fibers
Inventor: SIN HIN LO JASON
IPC: D01F9/12
Filed: 2004-12-17
Abstract: The present invention discloses the fabrication of polymer-coated, coated fiber composites, hybrid composites and a method and apparatus for fabricating the same. The invention provides for the maximum spraying and coating of a roving of coated fibers with molten polymer streams without making physical contact with a solid media, thus simultaneously preventing the fiber surface from getting damaged and stripping off the coating. When metal-coated fiber is used the invention improves the electromagnetic shielding properties of any subsequent product made from the inventive composite. The method and apparatus of the present invention uses sets of nozzle-type sprayers having multiple orifices to enable the thermoplastic or thermoset polymer to penetrate more efficiently into the fiber bundle, thereby providing a more uniform coverage of all fibers. The hybrid composites can consist of two or more types of reinforcements and one or more type of matrix polymer.
Patent CA-2490660-A1 (CA)
Inventor: MANOLE DAN M
IPC: F25B1/10
Filed: 2004-12-22
Abstract: A transcritical vapor compression system includes a fluid circuit circulating a refrigerant in a closed loop. The fluid circuit has operably disposed therein, in serial order, a compressor, a first heat exchanger, at least one non-variable expansion device and a second heat exchanger. The compressor compresses the refrigerant from a low pressure to a supercritical pressure. The first heat exchanger is positioned in a high pressure side of the fluid circuit. The second heat exchanger is positioned in a low pressure side of the fluid circuit. The at least one non-variable expansion device reduces the pressure of the refrigerant from a supercritical pressure to a relatively lower pressure. A refrigerant storage vessel is in fluid communication with the fluid circuit and contains a variable mass of refrigerant whereby the capacity of the system may be controlled.
Patent CA-2490724-A1 (CA)
Inventor: BATES PAULA J
IPC: C12Q1/68
Filed: 2003-04-08
Abstract: Methods for the diagnosis of cancer by determining the neoplastic status of a cell by probing the cell plasma membrane for the presence of nucleolin are provided, as are kits to carry out such tests.
Patent CA-2491775-A1 (CA)
Title: Positive pressure actuated aerator valve assembly
Inventor: DALMASSO CHRISTIAN
IPC: F16K31/122
Filed: 2005-01-10
Abstract: A positive pressure actuated aerator valve assembly adapted to discharge compressed gas into the chamber of a bulk material handling structure. The aerator valve assembly includes a housing and positive pressure actuated valve. The housing includes a chamber adapted to receive compressed gas and a discharge piston slideable between an extended position and a retracted position. The valve includes a valve body having an actuator piston seat and a fluid vent passageway in fluid communication with the actuator piston seat. An actuator piston is slideable with respect to the valve body between a retracted position and an extended position. A positive displacement force is applied to the actuator piston, such as by the supply of pressurized gas to the valve, to slide the actuator piston from the retracted position toward the extended position whereupon gas within the chamber of the housing flows through the fluid vent passageway and the discharge piston is moved from the extended position to the retracted position by gas within the chamber to thereby place the chamber of the housing in fluid communication with the fluid passageway of the piston seat.
Patent CA-2493249-A1 (CA)
Title: Armoured wheeled vehicle conposed of individual sections
Inventor: HOENLINGER MICHAEL
IPC: F41H7/02
Filed: 2003-07-16
Abstract: The invention relates to an armoured wheeled vehicle consisting of individual sections. Said vehicle consists of one driving section (1) containing a drive unit, and one mission section (2) which can be detached from the tail end of the driving section (1) and can be coupled to the vertical separating plane (T). Said driving section (1) and said mission section (2) respectively comprise a tail wall (4.1-4.5) or a front wall (5.1-5.5) in the coupling cross-section, and/or a frame profile which extends along at least part of the circumference thereof, and the tail wall and front wall applied against each other during the coupling process can be rigidly coupled together at at least two points on the circumference thereof by means of positively engaging coupling devices.
Patent CA-2496911-A1 (CA)
Inventor: DUBREAUIL JEAN
IPC: F16F7/00
Filed: 2003-08-22
Abstract: A foil-fluid bearing assembly (10) adapted for supporting a shaft (12) within an outer bearing housing (14). The foil-fluid bearing assembly (10) comprises a bearing sleeve (16) having an outer surface (20) and an inner circumferential surface (18) diametrically sized to receive the shaft (12) therewithin such that an annular clearance gap (24), radially defined between an outer surface (26) of the shaft (12) and the inner circumferential surface (18), is adapted for accommodating fluid therein and axially extends along a substantial portion of a length of the bearing sleeve (16), and has a foil element (28) disposed therewithin. Compliant bearing supports (30, 32) between the outer surface (20) of the bearing sleeve (16) and the outer bearing housing (14), comprises at least two independent compliant support elements (30, 32) respectively having a first and a second modulus of elasticity, wherein the first modulus of elasticity is less than the second modulus of elasticity. Angular misalignment capability for the foil-fluid bearing (10) is provided by the compliant support elements (30, 32).
Patent CA-2498196-A1 (CA)
Title: Phenolic polymer nanotube and process for producing the same
Inventor: KIJIMA TSUYOSHI
IPC: C08G8/04
Filed: 2003-03-05
Abstract: A phenolic polymer nanotube having a specific shape. It is obtained by conducting: a reaction step in which at least one monomer selected from the group consisting of phenols and derivatives thereof is reacted with aldehyde monomer in the presence of a basic condensation agent; a treatment step in which the precursor obtained in the reaction step is treated with a strong base; and a polymerization step in which the reactive precursor obtained in the treatment step is polymerized by dropping it into an aqueous solution containing the monomer and a surfactant.
Patent CA-2499014-A1 (CA)
Inventor: VARADHACHARY ATUL
IPC: A61K38/40
Filed: 2003-09-16
Abstract: The present invention relates to lactoferrin compositions and methods of using the compositions to treat wounds. The compositions can be administered alone or in combination with other standard wound healing therapies.
Patent CA-2499849-A1 (CA)
Title: Composite laminated sheet material for containment sumps
Inventor: FINK RONALD JAMES
IPC: B32B27/04
Filed: 2005-03-09
Abstract: The present invention is a composite laminated sheet material suitable for structures such as containment sumps. The laminated material comprises a fabric-backed thermoplastic layer upon which thermoset plastic is applied to the fabric side. The thermoplastic layer is formed by contacting a layer of fabric onto a lay er of molten thermoplastic such that the liquid thermoplastic permeates a portion of the fabric layer to form a mechanical bond with the fabric layer when the thermoplastic layer cools and hardens. Thermoset plastic, such as fibreglass resin, is sprayed onto the fabric side of the thermoplastic layer to allow the liquid resin to permeate the fabric layer. Once the resin cures and hardens, the fabric layer is mechanically bonded to the cured thermoset plastic layer to effectively bond the thermoplastic layer to the thermoset plastic layer.
Patent CA-2501185-A1 (CA)
Title: Method for producing logs of web material and rewinding machine implementing said method
Inventor: MADDALENI ROMANO
IPC: B65H19/22
Filed: 2003-10-14
Abstract: A method for producing logs (Ll, L2) of web material (N) wound around tubular cores wherein the tubular core (Al-A4) is equipped with glue to secure the initial end of the web material and allow winding. Part of the glue applied to the tubular core is transferred to the web material (N) before it is severed upon termination of winding the log, to seal the final free end of the formed log.
Patent CA-2503206-A1 (CA)
Inventor: COLLIS MATTHEW P
IPC: C12Q1/68
Filed: 2005-04-19
Abstract: A method includes creating a mixture in a container, the mixture including a sample containing at least one molecule of nucleic acid, at least one magnetically-responsive particle, and a remainder; and providing the mixture with a pH of less than about 7.0, thereby altering the surface charge properties of the at least one magnetically-responsive particle. The alteration in the surface change properties of the at least one magnetically-responsive particle causes the at least one molecule of nucleic acid to become non-specifically bound to the at least one magnetically-responsive particle to form a complex. Preferably, the at least one magnetically-responsive particle is uncoated, untreated, lacks surface modification, and has a diameter of about 0.1 µ to about 1.0 µ.
Patent CA-2504870-A1 (CA)
Title: Methods for the identification of agents that modulate the structure and processing of beta-amyloid precursor protein
Inventor: GELLERFORS PAR
IPC: C12N15/00
Filed: 2003-11-04
Abstract: The present invention provides methods for the screening and identification of agents from a large library of molecular structures that can alter the cleavage of amyloid precursor protein (AP). Agents identified by the methods of the present invention that modify the cleavage of APP can be used in the treatment and prevention of Alzheimer's disease. The methods select for and identify effector agents that bind to APP causing a structural change in the structure of APP in such a way that the efficiency of the cleavage of a secretase is modulated. Further, the methods are carried out in an in vivo system that provides for physiological conditions similar or identical to conditions for APP processing. Agents can be selected for their ability to cause a decrease in the amount of .szlig.-secretase or -secretase cleavage of APP, or for an increase in a-secretase cleavage of APP. The agents can be, particularly peptide agents, can be converted into a peptidominetic, an isosteric replacement compound, a D-amino acid analog, or non-peptidyl compound for treating Alzheimer's disease or any other amyloid related or prion related disease. The agents or derivatives thereof can be formulated for intravenous, parenteral, topical, sustained release, intranasal, or inhalation use.
Patent CA-2505260-A1 (CA)
Inventor: COLEMAN TERRENCE J
IPC: G06T5/20
Filed: 2003-11-06
Abstract: A multi-dimensional data enhancement system uses large kernel filtering, decimation, and interpolation, in multi-dimensions to enhance the multi- dimensional data in real-time (2). The multi-dimensional data enhancement system is capable of performing large kernel processing in real-time because the required processing overhead is significantly reduced (7). The reduction in processing overhead is achieved through the use of substantial low pass filtering and decimation that significantly reduces the amount of data that needs to be processed in order to generate an un-sharp mask comprising only very low spatial frequencies (9), that can be used to further process the da ta in a more natural way than is normally achieved with conventional edge sharpening.
Patent CA-2505361-A1 (CA)
Inventor: GUPTA JANG
IPC: C07D401/12
Filed: 2003-10-29
Abstract: The present invention relates to a phenyl or heteroaryl amino alkane derivatives which are useful as an active ingredient of pharmaceutical preparations. The phenyl or heteroaryl amino alkanes of the present inventio n have IP receptor antagonistic activity, and can be used for the prophylaxis and treatment of diseases associated with IP receptor antagonistic activity. Such diseases include urological diseases or disorder as follows: bladder outlet obstruction, overactive bladder, urinary incontinence, detrusor hyper - reflexia, detrusor instability, reduced bladder capacity, frequency of micturition, urge incontinence, stress incontinence, bladder hyperreactivity , benighn prostatic hypertrophy (BPH), prostatitis, urinary frequency, nocturi a, urinary urgency, pelvic hypersensitivity, urethritis, pelvic pain syndrome, prostatodynia, cystitis, or idiophatic bladder hypersensitivity. The compoun ds of the present invention are also useful for treatment of pain including, bu t not limited to inflammatory pain, neuropathic pain, acute pain, chronic pain , dental pain, premenstrual pain, visceral pain, headaches, and the like; hypotension; hemophilia and hemorrhage; and inflammation, since the diseases also is alleviated by treatment with an IP receptor antagonist.
Patent CA-2506783-A1 (CA)
Title: Manually operated fastening device
Inventor: BREWER KEVIN D
IPC: B25C5/00
Filed: 1995-08-08
Abstract: A fastening device is comprised of a housing having an operating lever pivotally mounted on the housing. A striker is located within the housing and oriented to drive a fastener from the housing. An actuator spring is coupled to the striker and adapted to bias the striker for driving the fastener from the housing. A firing lever is pivotally mounted on the housing and operable by the operating lever for raising the striker against the bias of the actuator spring. The firing lever is adapted to shift laterally relative to the striker and is normally located in a rest position. The firing lever is positioned to engage the striker when the operating lever is actuated to raise the striker. The firing lever is shifted laterally to release the striker for actuation by the actuator spring after the striker is raised. The operating lever has a pair of opposed lugs which receive a portion of the firing lever therebetween and engage opposite sides of the firing lever to guide the movement of the firing lever relative to the operating lever.