baber/WOPTO huggingface dataset:
Patent NZ-538337-A (NZ)
Title: Indolinone derivatives substituted in position 6, production and use thereof as medicaments for treating abnormal cell proliferation
Inventor: ROTH GERALD JUERGEN
Filed: 2003-07-22
Abstract: Disclosed herein are indoline or indolinone derivatives substituted in position 6 of general formula (I), wherein R1 to R6 and X are as defined in the specification, the tautomers, enantiomers thereof, the mixtures and salts thereof, especially physiologically compatible salts which have valuable pharmaceutical properties, especially an inhibiting effect on various receptor tyrosine kinases and on the proliferation of endothelial cells and various tumor cells, medicaments containing these compounds, the use thereof and a method for the production thereof.
Patent NZ-540357-A (NZ)
Title: Apparatus for dispensing activated monitoring devices
Inventor: ROBERTS WILLIAM PEYTON
IPC: G06F17/00
Filed: 2005-05-27
Abstract: The invention is a method and apparatus for dispensing an activated electronic monitoring device (EM device), such as a data logger. The invention can activate an EM device and verify activation before dispensing the EM device. The invention comprises a receptacle for storing a plurality of inactivated EM devices, a separator for separating an individual EM device, a reader for activating and verifying activation of the EM device, and a sorter for dispensing activated EM devices into an accept container that is readily accessible. EM devices that fail to activate can be dispensed into a reject container. In some embodiments, the apparatus includes a controller that typically comprises a microprocessor having stored instructions. The controller can typically communicate with the EM device via the reader to activate the EM device and verify activation. The controller may also be used to program or write instructions to the EM device.
Patent NZ-540696-A (NZ)
Title: Crystalline salt forms of topiramate
Inventor: ABDEL-MAGID AHMED
IPC: C07H11/00
Filed: 2003-12-30
Abstract: Disclosed is a crystalline salt of a compound of formula (I) wherein the salt of the compound of formula (I) is formed at the sulfamate group and is a choline salt. Also disclosed are processes of preparing said salt and pharmaceutical compositions comprising the salt.
Patent NZ-543149-A (NZ)
Title: Method and apparatus for calculating and displaying an optimal route between at least three locations
Inventor: GRAY DON CHANACHOK
IPC: G06Q10/08
Filed: 2004-04-30
Abstract: A method for generating and displaying and optimised route between a starting location and at least two destinations, and apparatus for carrying out the method are disclosed. A user enters the details of the locations. These are then converted into geographic data and an optimised route between the start location and destinations is calculated. The route is calculated so that the destinations are visited in an optimal order. A series of images are generated to show the calculated route, with each image clearly showing a section of the route.
Patent NZ-547118-A (NZ)
Title: A protective wire net, a protective structure constructed with the net, and the use of the protective wire net for the construction of a protective structure.
Inventor: FERRAIOLO FRANCESCO
IPC: E01F7/04
Filed: 2003-10-22
Abstract: A protective wire net comprises an array of longitudinal wires (12) arranged side by side and each intertwined with at least one respective adjacent longitudinal wire (12). Each of one or more longitudinal metal cables (14) is also intertwined with at least one adjacent longitudinal wire (12). One or more transverse wires (34) and/or metal cables (16) may also be provided, arranged in a transverse direction relative to the longitudinal wires (12) and outside intertwining regions (22) defined by portions (20) of adjacent longitudinal wires (12) which are bent around one another, the transverse wires (34) and/or metal cables (16) being intertwined or interlaced with one or more of the longitudinal wires (12).
Patent NZ-548137-A (NZ)
Title: A shower module with linings and channels and the channel configured to contain a drainage aperture
Inventor: WILLIAMSON GLEN
Filed: 2006-06-26
Abstract: A shower module including linings and channels has a continuous air gap maintained over the full height of the shower walls between the lining and walls of a building. The module is configured with at least one channel which contains a drainage aperture between the walls and linings.
Patent NZ-548201-A (NZ)
Title: Laminar flow lighted waterfall apparatus for spa
Inventor: MCDONALD CHRIS H
IPC: F21S8/00
Filed: 2004-10-07
Abstract: A laminar flow waterfall in the form of a single or multiple streams of water, each exiting from a nozzle in the top edge of a spa. The laminar water stream is created by a venturi nozzle located in a plenum chamber. The inlet side of the nozzle has a cover with a plurality of small holes forcing the water flow to enter the nozzle as laminar flow. A flow divider inside the venturi nozzle, from the inlet to the restriction of the nozzle, maintains the flow laminar through the nozzle. Light is injected into the flow divider at the inlet and is carried by the flow divider to be injected into the water flow at the restriction of the nozzle.
Patent NZ-550056-A (NZ)
Title: Lightweight portable roadway barrier having a weight of less than 200 kg/m that includes a structural framework and panels mounted on opposite sides of the structural framework
Inventor: HOTCHKIN DARREN JOHN
IPC: E01F13/02
Filed: 2005-03-03
Abstract: A lightweight, portable roadway barrier, is disclosed. The lightweight, portable roadway barrier is less than 200 kg per meter of length and is a stand alone barrier that does not require additional mass to function as a barrier. The barrier comprises; (a) a structural framework for resisting collapse of the barrier in response to impact of a vehicle; and (b) panels mounted to opposite sides of the structural framework for deflecting vehicles on impact with the barrier. The framework comprises upright members at opposite ends of the barrier and at least one upright member between the end members. At least one longitudinal member extends along the length of the barrier and is connected to each of the upright members.
Patent NZ-551204-A (NZ)
Title: Therapeutic peptides
Inventor: VIRJI MUMTAZ
IPC: C07K14/21
Filed: 2005-04-15
Abstract: Provided is an isolated polypeptide which is a truncated UspA1 protein comprising or consisting of a specified amino acid sequence which binds CEACAM receptors. Further provided are uses of the polypeptide in the manufacture of medicaments to treat various diseases, including infection, neoplastic diseases and dental caries.
Patent NZ-552398-A (NZ)
Title: Aryl-pyridine derivatives as 11-beta-HSD1 inhibitors for treatment of diabetes
Inventor: AMREIN KURT
IPC: A61K31/435
Filed: 2005-07-20
Abstract: Aryl-pyridine derivatives having the structure of formula (I) for use as 11-beta-HSD1 inhibitors to treatment of diabetes, diabetes Type II, obesity, eating disorder, dyslipidemiae and hypertension, wherein: R1 is hydrogen, alkyl, cycloalkyl, hydroxy, hydroxyalkyl, alkoxy, alkoxyalkyl, amino or aminoalkyl; R2 is hydrogen, alkyl or halogen; R3 is hydrogen, alkyl or halogen; R4 is phenyl, naphtyl, thiophenyl, pyridyl, quinolyl, piperidyl, morpholyl or thiomorpholyl optionally substituted with one or more substituents independently selected from alkyl, cycloalkyl, halogen, hydroxy, hydroxyalkyl, alkoxy, alkoxyalkyl, hydroxyalkoxy, alkoxyalkoxy, cyano, trifluoromethyl, trifluoromethoxy, aryl, arylalkyl, aryloxy, heterocyclyl, alkylcarbonylamino, alkoxycarbonylalkoxy and alkyl-SO2-; R5 is hydrogen or alkyl; R6, R7, R8, R9 and R10 are independently selected from hydrogen, alkyl, halogen, cyano, trifluoromethyl, alkoxy and alkyl-SO2-; A is nitrogen or C-R10; E is nitrogen or C-R9 G is nitrogen or C-R8; Wherein not more than one of A, E and G is nitrogen; and pharmaceutically acceptable salts and esters thereof.
Patent NZ-564542-A (NZ)
Title: Macrocyclic inhibitors of hepatitis C virus
Inventor: RABOISSON PIERRE JEAN-MARIE BERNARD
IPC: A61K31/4709
Filed: 2006-07-28
Abstract: Inhibitors of HCV of formula (I), and the N-oxides, salts, and stereoisomers thereof are disclosed, wherein the dashed line represents an optional double bond between atoms C7 and C8; R1 is hydrogen or C1-6alkyl; R2 is hydrogen or C1-6alkyl; and n is 3, 4, 5, or 6; pharmaceutical compositions containing compounds of formula (I) and processes for preparing compounds of formula (I) are provided. Bioavailable combinations of the inhibitors of HCV of formula (I) with ritonavir are also disclosed.
Patent NZ-567335-A (NZ)
Title: Immunomodulation using placental stem cells
Inventor: PALUDAN CASPER
IPC: A61K35/50
Filed: 2006-10-13
Abstract: Disclosed is the use of placental stem cells in the preparation of a medicament for suppressing an immune response, wherein said placental stem cells detectably suppress T cell proliferation stimulated by Epstein-Barr virus antigen-presenting B cells, and wherein at least 80% of said placental stem cells express CD200 and HLA-G; express CD73, CD105, and C0200; express CD200 and OCT-4; or express CD73, CD105, and HLA-G; and wherein said immune response is an immune response against an allograft, an autoimmune disease, diabetes, lupus erythematosus, rheumatoid arthritis, or multiple sclerosis, provided said placental cells are not totipotent.
Patent NZ-567951-A (NZ)
Title: Agricultural composition
Inventor: MARKS DAVID
IPC: C05D3/02
Filed: 2006-10-11
Abstract: Disclosed is an agricultural composition comprising: (i) a secondary nutrient or micronutrient; (ii) benzoic acid or a biologically acceptable derivative or salt thereof; and (iii) a water soluble jasmonate salt of formula (I) wherein R1 is a alkyl group, or a alkenyl group and M is a cation of valency n, wherein the secondary nutrient is calcium, magnesium, sodium, chloride or sulphur and the micronutrient is copper, cobalt, iron, manganese, boron, molybendum, zinc, silicon or nickel, and wherein the benzoic acid or biologically acceptable derivative or salt thereof is a compound of formula (V) where R4 is a group OR7, SR7 or NR7R8 where R7 and R8 are independently selected from hydrogen or hydrocarbyl, and R5 and R6 are independently selected from hydrogen, a hydrocarbyl group or a functional group, or R5 and R6 together with the carbon atoms to which they are attached form a fused ring system which may include one or more heteroatoms, selected from oxygen, nitrogen or sulphur. Also disclosed is a method to supply a secondary nutrient, enhance a nutrients uptake, prevent nutrient deficiency, prevent plant disease from nutrient insufficiency, improve growth under prolonged stress in plants comprising administering the composition and the use of said composition as a fertilizer.
Patent NZ-573915-A (NZ)
Title: Bead immobilization method involving casting a casting material over the casting surface to form a reverse casting
Inventor: NICOLAU DAN VENIAMIN
IPC: B29D16/00
Filed: 2007-06-27
Abstract: Disclosed is the bead immobilisation method and use of such method to make bead arrays for use mainly in biotechnology, pharmaceutical and medical industries. A bead immobilisation method first involves receiving at least one bead (130) in at least one well (120) in a casting surface (110). Then, a casting material (140) is casted over the casting surface (110) to form a reverse casting (150). The reverse casting (150) is then separated from the casting surface (110). The reverse casting (150) formed by such method includes a post (160) defined by the well (120) with the bead (130) casted onto the post (160) as shown in the drawing.
Patent NZ-577578-A (NZ)
Title: Switched reluctance linear motor/generator
Inventor: LUCAS TORRALBA JULIO
IPC: H02K16/00
Filed: 2007-11-12
Abstract: A linear switched reluctance motor/generator is disclosed. The linear switched reluctance motor/generator comprises: at least two translators and at least one stator wherein the stator is disposed between the at least two translators; two yokes with poles to which coils are attached so that magnetic flux created by the coils crosses the translators and the stator to close in itself; and several air gaps. The magnetic flux only closes through the two yokes, defined by two outermost stators, or two outermost translators, and is mostly perpendicular to air gaps of intermediate ferromagnetic elements. The motor/generator is driven by power electronic equipment configured to: close or open each phase at corresponding moments in which a reluctance variation is appropriate; increase a reluctance in a motor mode; and decrease the reluctance in a generator mode. The at least one stator comprises poles, and a set of intermediate coils are attached to the poles and configured to create additional flux and guide the magnetic flux through interior portion of the coils.
Patent NZ-578810-A (NZ)
Title: Method for producing sour milk products, method for treating milk therefor, sour milk production line
Inventor: MARCHENKO VIKTOR VASILIEVICH
IPC: A01J11/00
Filed: 2005-08-08
Abstract: Disclosed is a method for treating milk including pasteurization with double pasteurization, and bottling with hermetic sealing, the method including; (a) after a first pasteurization, the milk is kept at 68-72 Deg. C for not less than 15 minutes for drinking milk and not less than 5 minutes for sour milk products; (b) bottling with hermetic sealing whilst maintaining the temperature at step a; (c) then the hermetically sealed milk is cooled to 12-37 Deg. C and kept at this temperature for not less than 30 minutes; (d) subsequently carrying out a second pasteurization by heating the milk to 68-72 Deg. C at a rate which is not less than 10 Deg. C per second temperature increase.
Patent NZ-579482-A (NZ)
Title: Antibody drug conjugates and methods
Inventor: EBENS ALLEN J
IPC: A61K47/48
Filed: 2005-05-31
Abstract: Disclosed is a composition comprising a mixture of antibody-drug conjugate compounds, wherein each antibody-drug conjugate compound comprises an antibody covalently attached by a linker to one or more maytansinoid drug moieties, the compound having Formula I: Ab-(L-D)p or a pharmaceutically acceptable salt or solvate thereof, wherein: Ab is a human or humanized antibody which binds to CD22; L is a linker selected from a number of specified structures and p = 1-8. (62) Divided Out of 551180
Patent NZ-579986-A (NZ)
Title: 3-cyano-4-(4-phenyl-piperidin-1-yl)-pyridin-2-one derivatives
Inventor: CID-NUNEZ JOSE MARIA
IPC: C07D401/04
Filed: 2008-03-07
Abstract: Disclosed is a 3-cyano-1-alkyl-4-(-4-phenyl-piperidin-1-yl)-pyridine-2(1H)-one compound of formula (I) including any stereo chemically isomeric form thereof, wherein R1 is alkyl; R2 is hydrogen; hydroxyl; fluoro; alkyl substituted with hydroxyl; alkyl with fluoro; or alkyloxy substituted with fluoro; R3 is hydrogen or halo; or a pharmaceutically acceptable salt thereof or a solvate thereof; for treating or preventing a central nervous system disorder selected from the group of anxiety disorders, psychotic disorders, personality disorders, substance-related disorders, eating disorders, mood disorders, migraine, epilepsy or convulsive disorders, childhood disorders, cognitive disorders, neurodegeneration, neurotoxicity and ischemia. Also disclosed is a process for preparing a compound as claimed in claim 1, characterized by a) reacting an 3-cyano-pyridin-2(1H)-one intermediate of formula (II) wherein Y represents a suitable leaving group, with an 4-piperidine intermediate of formula (III) in a suitable reaction-inert solvent, in the presence of a suitable base, under heating conditions or reacting an intermediate of formula (II) with an intermediate of formula (III) in a suitable reaction-inert solvent, in the presence of a suitable base, a suitable catalyst, under heating conditions; reacting a compound of formula (I-b) with a suitable fluorinating agent in a suitable reaction-inert solvent, under a moderately low temperature; c) reacting an intermediate of formula (IV) with a suitable fluorinating agent in a suitable reaction-inert solvent, under a moderately low temperature; d) hydrogenating an intermediate of formula (XIV) in a suitable solvent and in the presence of a suitable catalyst and a suitable base.
Patent NZ-581547-A (NZ)
Title: Pyrazolone derivatives as phosphodiesterase type 4 inhibitors
Inventor: SCHMIDT BEATE
IPC: C07D417/14
Filed: 2008-05-14
Abstract: A compound of formula (1) wherein R1 represents a phenyl derivative of formula (a) or (b). R2 is selected from the group consisting of 1-2C-alkoxy and 1-2C-alkoxy which is completely or predominantly substituted by fluorine; R3 is selected from the group consisting of 1-2C-alkoxy, 3-5C-cycloalkoxy, 3-5C-cycloalkylmethoxyand 1-2C-alkoxy which is completely or predominantly substituted by fluorine; R4 is selected from the group consisting of 1-2C-alkoxy and 1-2C-alkoxy which is completely or predominantly substituted by fluorine; R5 is 1-2C-alkyl and R6 is selected from the group consisting of hydrogen and 1-2C-alkyl; or R5 and R6 together and with inclusion of the two carbon atoms, to which they are bonded, form a spiro-linked 5- or 6-membered hydrocarbon ring; R7 is 1-3C-alkyl and R8 is 1-3C-alkyl or R7 and R8 together with the carbon atom, to which they are bonded, form a spiro-linked 3-, 4-, 5- or 6-membered hydrocarbon ring, R9 is-N(R11)R12, R11 and R12 together and with inclusion of the nitrogen atom to which they are bonded, form a heterocyclic ring selected from the group consisting of a pyrrolidin-2,5-dione-1-yl-, isoindol-1,3-dione-2-yl-, 2-oxo-2,3-dihydro-1 H-indol-1-yl-, pyrrolidin-2-one-1-yl-, piperidin-2,6-dione-1-yl-,morpholin-3,5-dione-4-yl-, thiomorpholin-3,5-dione-4-yl-, thiomorpholine-1-oxide-3,5-dione-4-yl- and a thiomorpholine-1, 1-dioxide-3,5-dione-4-yl-ring; and n is 1 or 2; or a stereoisomer of the compound. The compound is used as a phosphodiesterase type 4 (PDE4) inhibitor for treatment of acute or chronic airway diseases and for the treatment or prophylaxis of allergic rhinitis. An example of the compound of formula 1 is 1-(2-{ 4-[3-(3,4-dimethoxyphenyl)-4,4-dimethyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]piperidin-1-yl} -2-oxoethyl)pyrrolidine-2,5-dione.
Patent NZ-584422-A (NZ)
Title: Price reduction label and price reduction label applying method
Inventor: HONDA SATORU
IPC: G09F3/02
Filed: 2008-10-30
Abstract: 584422 A price reduction label which is used without backing paper and displays a new price applied over the price indication of an article. The price indication label includes a label body with an upper surface forming an indication surface of the new price and a back surface forming a contact surface applied to the article. The label has an adhesive region on the back surface of the label body coated with adhesive material. The adhesive region includes spaced and strip-shaped plural rows. The label has a non-adhesive region on the back surface of the label body. The non-adhesive region includes the areas without the adhesive material and is positioned between the plural rows of the adhesive material. The label has a release region coated with release material and a non-release region without the release material. Both the release and non-release regions are formed on the upper surface of the label body. The release regions are shaped spaced to correspond with a respective row of the adhesive material. The non-release regions and the adhesive regions include reapplication preventing slits. The reapplication preventing slit formed in the non-release region is configured to tear the label body when a new label applied over said label is removed. The reapplication preventing slit formed in the adhesive region is configured to tear the label body when the label is removed from a label thereunder.
Patent NZ-585057-A (NZ)
Title: Method of pooling samples for performing a biological assay
Inventor: VEREIJKEN ADRIANUS LAMBERTUS JOHANNUS
IPC: C12Q1/68
Filed: 2008-10-31
Abstract: A method for pooling samples to be analysed for a categorical variable. The method comprises providing a pool of n samples wherein the amount of individual samples in the pool is such that the analyte in the samples are present in a molar ratio of x0:x1:x2:x(n-1), wherein x represents the number of classes of the categorical variable and is an integer of 2 or higher. The method can be used to pool samples of nucleic acids and the categorical variable to be quantitatively measured is a single nucleotide polymorphism (SNP).
Patent NZ-586957-A (NZ)
Title: Cell lines and methods for making and using them
Inventor: SHEKDAR KAMBIZ
IPC: C07K14/435
Filed: 2009-02-02
Abstract: NZ 586957 Disclosed is a matched panel of clonal cell lines of the same cell type, wherein the matched panel comprises at least six clonal cell lines, wherein each cell line in the panel expresses an RNA of interest or a protein of interest, and wherein cell lines in the panel are matched for a physiological property, wherein the physiological property is selected from the group consisting of: growth rate, wherein said growth rate is measured in doubling time and the difference between the doubling times of the fastest and slowest growth rates in any group is no more than 5 hours; Z’ factor, wherein the Z’ factors of each of the clonal cell lines in the panel does not differ by more than 0.1 of every other cell line in the panel; expression level of the RNA of interest, wherein the expression levels of each of the clonal cell lines in the panel does not differ by more than 30% of every other cell line in the panel; expression level of an RNA encoding the protein of interest, wherein the expression levels of each of the clonal cell lines in the panel does not differ by more than 30% of every other cell line in the panel; and expression level of the protein of interest, wherein the expression levels of each of the clonal cell lines in the panel does not differ by more than 30% of every other cell line in the panel.
Patent NZ-588365-A (NZ)
Title: Method and arrangement for attachment and/or disassembly/assembly of a tunnel thruster
Inventor: ANDERSSON LARS-GORAN
IPC: B63B9/00
Filed: 2009-04-02
Abstract: Disclosed is a method and an assembly/disassembly arrangement for a tunnel thruster unit. The arrangement comprises a thruster unit (2) and a first attachment arrangement (31, 23) for fitting of said thruster unit to a tunnel (3, 4). At least one further attachment arrangement (102,104) exists for safe fitting of said thruster unit in the tunnel. This further attachment arrangement is in the form of a first interface device fixedly attached to and protruding from the inside of the tunnel wall and a second interface device fixedly attached to said thruster unit.
Patent NZ-590125-A (NZ)
Title: Peptide MHC I analogue comprising the sequence EAAGIGILTIV and use of peptide to induce or regulate a T-cell response
Inventor: BOT ADRIAN
IPC: A61K38/00
Filed: 2006-06-16
Abstract: Disclosed are peptide analogues and immunogenic compositions comprising the sequence EAAGIGILTIV corresponding to Class I MHC-restricted T cell epitopes. The disclosed sequence may comprise selected substitutions. Also disclosed is the use of the peptides in medicaments for amplifying a CTL response and for entraining a Class I MHC-restricted T cell response.