Patent SG-11201901175Y-A (SG)
Title: Cell rupture-based antimicrobial surfaces coated with metal oxide nano-arrays
Inventor: ZHANG YUGEN
IPC: C09D5/14
Filed: 2017-09-19
Abstract: WO 18/05 690 4 A 3,1i , • (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 29 March 2018 (29.03.2018) WIPO I PCT 0111111010 0111 °nolo III m Immo oimIE (10) International Publication Number WO 2018/056904 Al [Fig. 5] (51) International Patent Classification: CO9D 5/14 (2006.01) B82B 3/00 (2006.01) AO1N 25/34 (2006.01) B82Y 30/00 (2011.01) AO1P 1/00 (2006.01) (21) International Application Number: PCT/SG2017/050472 (22) International Filing Date: 19 September 2017 (19.09.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 10201607858V 20 September 2016 (20.09.2016) SG (71) Applicant: AGENCY FOR SCIENCE, TECHNOLO- GY AND RESEARCH [SG/SG]; 1 Fusionopolis Way, #20-10 Connexis North Tower, Singapore 138632 (SG). (72) Inventors: ZHANG, Yugen; c/o Institute of Bioengineer- ing and Nanotechnology, 31 Biopolis Way, #08-08 Nanos, Singapore 138669 (SG). YI, Guangshun; c/o Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, #08-08 Nanos, Singapore 138669 (SG). (74) Agent: SPRUSON & FERGUSON (ASIA) PTE LTD; P.O. Box 1531, Robinson Road Post Office, Singapore 903031 (SG). ( 81 ) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: — of inventorship (Rule 4.17(iv)) Published: — with international search report (Art. 2 I (3)) (54) Title: CELL RUPTURE-BASED ANTIMICROBIAL SURFACES COATED WITH METAL OXIDE NANO-ARRAYS (57) : The present disclosure relates to an antimicrobial coating on a surface, a method for preparing and uses of the same. In particular it relates • ‘ to a process for preparing an antimicrobial coating on a surface, the process comprising the steps of: a) providing a surface; b) coating a metal oxide or a metal hydroxide on the surface in the presence of a solvent in a hydrothermal synthesis step to form a coated surface having a plurality of nanostructures; c) optionally drying the coated surface, wherein said nanostructure is preferably in nanopillar structure. The coating of the present application exhibits excellent antimicrobial activity against different types of microorganism, such as bacteria and yeast. The nanostructures are able to exert stress to the microorganism, and therefore controlling or killing them.