baber/WOPTO huggingface dataset:
Patent CA-3180981-A1 (CA)
Title: Methodes pour le traitement de troubles d'expansion de repetitions trinucleotidiques associes a une activite msh3
Inventor: BERMINGHAM NESSAN ANTHONY
IPC: A61K31/125
Filed: 2020-06-03
Abstract: La présente invention concerne des compositions et des méthodes utiles pour traiter des troubles d'expansion de répétitions trinucléotidiques, par exemple, chez un sujet en ayant besoin. Dans certains aspects, les compositions et les méthodes décrites dans la description sont utiles dans le traitement de troubles associés à l'activité de MSH3. Certains aspects de l'invention concernent un oligonucléotide simple brin de 15-30 nucléotides liés en longueur, l'oligonucléotide, ou une partie de celui-ci, étant au moins 95 % complémentaire d'au moins 15 nucléobases contiguës à des positions 2543-2573 de SEQ ID NO : 614, ou un sel pharmaceutiquement acceptable de celui-ci.
Patent CA-3181683-A1 (CA)
Inventor: PARCQ JULIEN
IPC: A61K9/00
Filed: 2021-06-16
Abstract: The invention relates to a water insoluble solid crosslinked dextrin-based matrix, wherein the crosslinking agent is sodium trimetaphosphate (STMP), its use and method of preparation.
Patent CA-3185382-A1 (CA)
Inventor: HOWE KATHRYN
IPC: C12Q1/6813
Filed: 2022-12-16
Abstract: Recent literature on SARS-CoV-2 pathogenesis has suggested that the induction of substantial acute respiratory distress phenotypes is driven by a mismatched inflammatory response together with broad vascular dysfunction. While several detailed reports implementing multi-omic approaches have provided insight into the immune cell phenotypes involved in these processes, risk stratifying markers specific to COVID-19 and the vasculature have not been explored.  Provided herein is a comprehensive, multi-omics-based description of the molecular antecedents to COVID-19 mortality, yielding new insights pertaining to the vasculature while highlighting the urgent need for clinical translation of novel biomarkers for disease prognosis.
Patent CA-3186421-A1 (CA)
Inventor: LUNDQVIST CHRISTOFFER
IPC: A61K8/99
Filed: 2021-06-30
Abstract: The present invention relates to the field of topical compositions comprising probiotic bacteria showing improved properties for storage and stability. More particularly, the invention relates to such topical compositions for cosmetic and medical use and to containers and kits comprising such compositions. Storing the compositions in containers together with a solid support comprising a desiccant polymer was proven to provide excellent storage prerequisites to the composition comprising the probiotic bacteria.
Patent CA-3188565-A1 (CA)
Title: Coating composition with high solids content, and method for forming multilayer coating film
Inventor: FURUYA DAISUKE
IPC: C09D167/00
Filed: 2021-08-04
Abstract: The present invention relates to a coating composition with a high solids content that includes: (A) a hydroxyl group- and alkoxysilyl group-including acrylic resin; (B) a hydroxyl group-including polyester resin; and (C) a polyisocyanate compound, wherein the acrylic resin (A) content is 20-50 parts by mass per 100 parts by mass of the resin solids content of the coating composition with a high solids content, the polyester resin (B) has an acid number of 10 mg KOH/g or less, a hydroxyl number of 180-300 mg KOH/g, and a number average molecular weight of 400-1500, and at the time of coating, the solids content of the coating composition with a high solids content is 50 mass% or greater.
Patent CA-3189718-A1 (CA)
Title: Dispositifs de chauffage pour dispositifs medicaux
Inventor: LAMBLE RALPH
IPC: B01L3/00
Filed: 2021-08-26
Abstract: L'invention concerne un dispositif médical comprenant une carte de circuit imprimé multicouche (PCB) comprenant un élément chauffant sur une couche interne de la PCB ; une source d'énergie électrique à cellule unique pour alimenter l'élément chauffant ; et une chambre conçue pour contenir un liquide, au moins une partie de ladite chambre étant définie par un matériau thermo-conducteur conçu pour fournir une interface de transfert thermique entre la chambre et la PCB.
Patent CA-3192282-A1 (CA)
Inventor: SIMANZHENKOV VASILY
IPC: C07C5/48
Filed: 2021-10-06
Abstract: A chemical complex to perform oxidative dehydrogenation of C2-C4 alkanes, to C2-C4 alkenes, the chemical complex involving at least one oxidative dehydrogenation reactor containing one or more mixed metal oxide catalysts and designed to accept, optionally in the presence of a heat removal diluent gas, an oxygen containing gas and a C2-C4 alkane containing gas, and to produce a product stream including a corresponding C2-C4 alkene and one or more of: an unreacted C2-C4 alkane; oxygen; heat removal diluent gas; carbon oxides, including carbon dioxide and carbon monoxide; oxygenates, including but not limited to, one or more of acetic acid, acrylic acid and maleic acid; and water; and involving a combustion chamber for combusting a product stream and at least one fuel stream and optionally at least one stream including oxygen, the combustion chamber producing a flue gas at a temperature of 850°C to 1500°C.
Patent CA-3192899-A1 (CA)
Title: Process for preparing cold fusion concrete and cement compositions from metal mining and production waste
Inventor: ZUBROD RODNEY
IPC: C04B7/147
Filed: 2023-03-13
Abstract: Methods of preparing cold fusion concrete and cement using mining waste are described.
Patent CA-3192901-A1 (CA)
Title: Mobile fulfillment container apparatus, systems, and related methods
Inventor: KIM JONATHAN
IPC: G06Q10/0836
Filed: 2023-03-13
Abstract: Mobile fulfillment container apparatus, systems, and related methods are disclosed. An example mobile container includes a storage area to move between a locked state and an unlocked state to provide access to inventory in the storage area; an electronic gating sensor to detect when the inventory has been removed from the storage ai-ea; and processor circuitry to output an instruction including a destination for the mobile container based on an order associated with the inventory.
Patent CA-3194108-A1 (CA)
Inventor: MORI TOMONORI
Filed: 2016-08-26
Abstract: A drum unit includes a photosensitive drum in a coupling member. The coupling member includes an engageable member having a driving force receiving portion which is capable of entering a recess of a driving shaft to receive a driving force for rotating photosensitive drum.  The coupling member includes a holding member configured to hold said engageable member so as to be slidable at least in a radial direction of said drum unit.
Patent CA-3197078-A1 (CA)
Title: Undercarriage wear prediction using machine learning model
Inventor: ZHANG LI
IPC: G05B23/02
Filed: 2021-10-04
Abstract: A system may comprise a device. The device may be configured to receive, from one or more sensor devices of the machine, sensor data associated with wear of one or more components of an undercarriage of the machine; and predict, using a machine learning model and the sensor data, an amount wear of the one or more components based on a wear rate of the one or more components. The machine learning model is trained, using training data, to predict the wear rate of the one or more components. The training data includes two or more of: historical sensor data, historical inspection data, or simulation data, of a simulation model, from one or more third devices. The device may perform an action based on the amount of wear.
Patent CA-3200014-A1 (CA)
Title: Novel compositions with tissue-specific targeting motifs and compositions containing same
Inventor: WILSON JAMES M
IPC: C07K14/005
Filed: 2021-12-01
Abstract: Provided herein are compositions including targeting peptides linked thereto or inserted in a targeting protein of a recombinant vector having at least one exogenous peptide comprising an amino acid sequence of N- x- (T/I/V/A)- (K/R) (SEQ ID NO: 47). Compositions providing such conjugates, targeting peptides, or recombinant vectors having a mutant capsid or envelope protein are provided as are uses thereof.
Patent CA-3200546-A1 (CA)
Title: Fibreglass reinforced plastic
Inventor: BEALE LEWIS JOHN
IPC: C08L101/00
Filed: 2021-10-01
Abstract: Provided herein is a resin composition containing milled fibreglass and graphene. Also provided herein is a composite material containing cured resin composition, fibreglass reinforced resin containing the composite material and further fibreglass, a laminate including a layer of the fibreglass reinforced resin, and methods of making the resin composition, composite material and fibreglass reinforced resin. The composition, composite material and fibreglass reinforced resin and laminate find use in, for example, the construction of swimming pools and spa pools.
Patent CA-3202640-A1 (CA)
Inventor: TRABACE SIMONA
IPC: C07D487/04
Filed: 2022-02-18
Abstract: The present invention relates to a Larotrectinib synthesis process with a 3-O- sulfonylated impurity content lower than 0.10% by weight. A further object of the invention is the compound 3-O-sulfo-Larotrectinib ((3S)-N-[5-[(2R)-2- (2, 5 -Difluorophenyl)- 1- pyrrolidinyl] pyrazole [1,5- a] pyrimidine-3-yl]-3 -hydroxy sulphonyloxy-1- pyrrolidinecarboxamide), hereinafter referred to as S-Larotrectinib, useful as an analytical standard to evaluate the purity of Larotrectinib.
Patent CA-3202681-A1 (CA)
Title: Improvements in or relating to handling of mail items
Inventor: GALLEY CHRIS
IPC: G07B17/00
Filed: 2021-12-17
Abstract: A method of verifying the identity of a mail item, the method comprising obtaining a first visual representation of at least a portion of a mail item, determining a first postal identifier based on the first visual representation, obtaining a second visual representation of at least a portion of the mail item, determining a second postal identifier based on the second visual representation, comparing the second postal identifier with the first postal identifier, and enabling processing of the mail item based on the comparison step.
Patent CA-3206087-A1 (CA)
Inventor: ABEIDOH ABDEL-HAMID RAWHI
IPC: E21B33/14
Filed: 2021-05-18
Abstract: Methods and systems for cementing in a wellbore. An example method includes introducing a conduit into a wellbore. The conduit comprises a reactive metal element disposed on an exterior of the conduit. The reactive metal element comprises a reactive metal having a first volume. The method further includes circulating a cement over the exterior of the conduit and the reactive metal element, contacting the reactive metal element with a fluid that reacts with the reactive metal to produce a reaction product having a second volume greater than the first volume, and contacting a surface of the cement adjacent to the reactive metal element with the reaction product.
Patent CA-3206502-A1 (CA)
Title: Crystal form of methylpyrazole-substituted pyridoimidazole compound and preparation method therefor
Inventor: CHEN ZHENGXIA
IPC: C07D471/04
Filed: 2022-01-26
Abstract: A crystal form of a methylpyrazole-substituted pyridoimidazole compound (II) and a preparation method therefor.
Patent CA-3210933-A1 (CA)
Inventor: VAINIKKA PASI
IPC: C25B1/04
Filed: 2022-02-18
Abstract: Disclosed is a method of growing a microbial mass (202). The method comprises collecting biowaste (206) from an organism, the biowaste comprising a first amount of water (208) and a first amount of solid-phase (210); receiving the collected biowaste in a first reactor (212); treating the collected biowaste in the first reactor using a first set of operating parameters for a first period of time to dissolve at least a part of solid-phase inorganic nutrients into the first amount of water to form a growth media (216); washing the formed growth media, wherein said washing includes sterilization, separation and cleaning steps; providing the formed growth media to a second reactor (228) comprising an inoculum of microbial mass; collecting carbon dioxide locally from an atmosphere; collecting a second amount of water present in the atmosphere and splitting the collected second amount of water into oxygen and hydrogen gas; providing the collected carbon dioxide and the split oxygen and hydrogen gas to the second reactor; growing a microbial mass in the second reactor under a second set of operating parameters; and harvesting the grown microbial mass from the second reactor to produce food for consumption by the organism.
Patent CA-3211943-A1 (CA)
Title: Treatment of rna virus infection with a cytidine deaminase inhibitor
Inventor: SAUNTHARARAJAH YOGEN
IPC: A61K31/7072
Filed: 2022-03-22
Abstract: The present invention provides compositions, systems, kits, and methods for treating a subject with an RNA virus infection (e.g., SARS-CoV-2) by administering or providing a composition comprising a cytidine deaminase inhibitor (e.g., tetrahydrouridine or cedazuridine).
Patent CA-3214155-A1 (CA)
Title: Procedes d'inhibition de ras
Inventor: CORCORAN RYAN B
IPC: C07K14/47
Filed: 2022-04-01
Abstract: La divulgation concerne des procédés d'inhibition de protéines RAS, par exemple, des protéines RAS qui ont acquis une résistance à un ou à plusieurs inhibiteurs de RAS. L'invention concerne également des méthodes pour le traitement du cancer.
Patent CA-3214265-A1 (CA)
Inventor: INN KYUNG-SOO
IPC: C07J43/00
Filed: 2021-04-06
Abstract: La présente invention concerne un nouveau dérivé d'acide aminé, son procédé de préparation et une composition pharmaceutique pour le traitement de l'hépatite B ou D comprenant ledit dérivé. Un composé représenté par la formule chimique 1, selon la présente invention, présente l'excellent effet d'inhibition de la liaison du peptide preS1 du VHB par liaison à <i />NTCP, de manière à présenter l'effet consistant à inhiber l'entrée intracellulaire et l'adhérence cellulaire du VHB, et peut ainsi être utilisé en tant que composition pour prévenir, traiter ou soulager des maladies provoquées par une infection par le VHB et le VHD.
Patent CA-3214741-A1 (CA)
Title: Blockchain key generation
Inventor: POSCHKE NILS
IPC: H04L9/40
Filed: 2022-04-06
Abstract: Method and system for generating transactions comprising defining one or more conditions for a transaction. Adding the one or more conditions to blocks within a distributed ledger. Generating by a first device, an offer for a digital asset, wherein the offer is digitally signed by a secure applet executing within a UICC of the first device. Generating by a second device, a request for the digital asset, wherein the request is digitally signed by a secure applet executing within a UICC of the second device. Authenticating the digital signatures of the offer and of the request. Determining that the offer and request meet the one or more conditions added to the distributed ledger and if the one or more conditions are met by the offer and the request then digitally signing the digital asset by the secure applet executing within the UICC of the first device. Transmitting the signed digital asset from the first device to the second device. Authenticating the digital signature of the signed digital asset and adding to a block on the distributed ledger, a transaction recording the transmission of the digital asset from the first device to the second device.
Patent CA-3215063-A1 (CA)
Title: Hybrid, artificial bone tissue implant absorbing mechanical vibrations, whose architectural structure imitates trabecular bone, allowing the saturation of bone marrow, blood, and nutrients, supporting autological regeneration, which can be used with titanium structure
Inventor: HURI GAZI
IPC: A61L27/06
Filed: 2021-12-26
Abstract: This invention is based on the creation of a polymer scaffold structure as a result of the proportional combination of ?-Tricalcium Phosphate (?-TCP) that will increase the 3D and osteoconductive effect allowing/supporting cell infiltration by using extrusion deposition, in other words, added manufacturing process, and with physiological buffered HA solution with the Deep Coating Method and by increasing the transmission rate of growth factors as a result of coating and expanding their areas with the biological tissue implant, which allows its use with titanium mesh plates or contoured structures.
Patent CA-3215750-A1 (CA)
Inventor: YAMASHITA YUKI
IPC: A61K31/353
Filed: 2022-03-29
Abstract: L'invention concerne des gouttes ophtalmiques en suspension ayant une redispersibilité supérieure. La présente invention concerne un agent de suspension aqueux qui contient du (E)-2-(7-trifluorométhylchroman-4-ylidène))-N-(7-hydroxy-5,6,7,8-tétrahydronaphtalène-1-yl) acétamide ou un sel ou solvate pharmaceutiquement acceptable de celui-ci, un polymère à base de cellulose et un tensio-actif non ionique.
Patent CA-3215990-A1 (CA)
Inventor: BUCHOLZ BRANDON
IPC: A47C7/46
Filed: 2019-11-05
Abstract: A seating or furniture assembly includes a seat bottom, a seatback, and a lumbar adjustment assembly. The seatback is disposed adjacent the seat bottom and includes a seatback frame. The lumbar adjustment assembly is mounted to the seatback frame and includes a rail, a threaded rod disposed within the rail, a first slider block slidably engaging the rail, a second slider block slidably engaging the rail, a lumbar pad, and a plurality of links connecting the lumbar pad to the first and second slider blocks. The threaded rod includes a first threaded section having threads with a first handedness and a second threaded section having threads with a second handedness that is opposite the first handedness. The first slider block threadably engages the first threaded section. The second slider block threadably engages the second threaded section.
Patent CA-3218166-A1 (CA)
Inventor: WOZNIAK ELIZABETH MARIA
IPC: C05F11/08
Filed: 2021-08-04
Abstract: L'invention concerne des compositions de traitement du sol, des produits, des systèmes, des kits et des procédés pour augmenter la quantité, le niveau, le rapport ou la proportion de phosphore soluble et/ou biodisponible dans le sol, pour solubiliser le phosphore, pour augmenter ou améliorer la biodisponibilité du phosphore dans le sol, pour améliorer la fertilité du sol, pour augmenter la production de cultures, pour réduire les exigences d'engrais en phosphore, etc. L'invention concerne des compositions d'engrais bioactivés et des procédés associés pour augmenter la solubilité et/ou la biodisponibilité du phosphore dans le sol.
Patent CA-3219105-A1 (CA)
Title: Cosmetic compositions comprising a barbary fig extract for moisturising keratin fibres
Inventor: DAUNES-MARION SYLVIE
IPC: A61K8/34
Filed: 2022-05-20
Abstract: The present invention relates to the use of a Barbary fig extract for tightening the scales of keratin fibres.
Patent CA-3221901-A1 (CA)
Title: Cellules metal-air avec acces a l'air minimal
Inventor: RUBSAM TONY
IPC: H01M12/06
Filed: 2022-06-28
Abstract: L'invention concerne une batterie comprenant une cathode à air, une anode, un électrolyte aqueux, et un boîtier, dans lequel, le boîtier comprend un ou plusieurs orifices d'accès à l'air définissant une zone d'évent totale, la batterie présente une densité de courant, un rapport de densité de courant à la surface d'évent totale est supérieur à environ 100 mA/mm2, et l'électrolyte aqueux comprend un tensioactif fluoré amphotère.
Patent CA-3222504-A1 (CA)
Title: Polymer recyclate processes and products
Inventor: MAVRIDIS HARILAOS
IPC: C08J11/12
Filed: 2022-06-21
Abstract: Methods for processing LLDPE recyclates including, but not limited to, polyethylene and polypropylene and compositions therefrom are provided. LLDPE recyclate can be visbroken to improve processing characteristics and/or devolatilized to remove waste byproducts to produce processed LLDPE recyclates. Processed LLDPE recyclates are compounded with pre-consumer polyolefins to produce blend compositions having acceptable or even improved processing characteristics. Such pre-consumer polyolefins can also be visbroken to further tailor processing characteristics of such polymer blends. A combination of extruders and/or extruder zones can be used at the same or different locations for visbreaking and/or compounding of both LLDPE recyclate and/or pre-consumer polyolefins.
Patent CA-3223809-A1 (CA)
Inventor: SAVVIDES SAVVAS
IPC: C12N9/12
Filed: 2022-07-04
Abstract: The present invention provides co-crystals of the anaplastic lymphoma kinase (ALK) and its ligand ALKAL2 and the related leukocyte tyrosine kinase (LTK) and its ligand ALKAL1. The invention also provides computer-assisted and other methods for selecting molecules able to modulate the interaction between ALK, LTK and their respective ligands.
Patent CA-3224003-A1 (CA)
Title: Ensemble de cellules de charge pour un appareil de support de patient
Inventor: GUNCAN BERKAY
IPC: A61G7/018
Filed: 2022-10-13
Abstract: Un appareil de support de patient comprend une structure de support comprenant une base, un cadre intermédiaire et un plateau de support de patient et un mécanisme de levage pour déplacer le plateau de support de patient par rapport à la base. Une pluralité de cellules de charge sont intercalées entre le mécanisme de levage et la structure de support pour mesurer la charge autour de la surface de support de patient. Chacun de la pluralité d'ensembles de cellules de charge comprend un corps, une douille et une tige. La douille est conçue pour être reçue par le corps et définit des régions effilées opposées et une région centrale. La tige est conçue pour être reçue par la douille et définit une région de diamètre réduit agencée pour venir en prise avec la région centrale de la douille pour pousser la tige en alignement avec la douille et pour permettre un mouvement de pivotement et de translation limité entre la tige et la douille en réponse à un décalage de charge entre la pluralité d'ensembles de cellules de charge.
Patent CA-3224279-A1 (CA)
Inventor: GAMBICHLER CAROLINE
IPC: C04B26/04
Filed: 2021-07-02
Abstract: The invention relates to a mixture for covering joints between building boards in drywall constructions, which can be applied by spraying, wherein the mixture contains 0.01 to 10 wt.-% of a fibrous material, 1 to 20 wt.-% of a binder, 1 to 10 wt.-% of a thickener and 50 to 97.99 wt.-% of a solvent, and in which the fibrous material and the binder are present in a predetermined ratio in the range from 1 :1 to 1 :5. The present invention also relates to a method for filling joints in drywall constructions using such mixture, drywall constructions produced accordingly and the use of the sprayable mixtures described for reinforcing a drywall construction in the contact area between construction panels.
Patent CA-3224585-A1 (CA)
Inventor: KIM CHUNSHIK
IPC: A47J43/046
Filed: 2022-06-23
Abstract: A liquid brewing device includes a base housing a motor and at least one base magnet rotatable by the motor relative to the base, a pitcher having an interior volume, and a brew basket for receiving brewing ingredients, the brew basket being removably and insertably positioned in the interior volume of the pitcher. An agitator is positioned entirely within and rotatable relative to the brew basket, the agitator being operatively coupled to at least one agitator magnet. The at least one agitator magnet is magnetically coupler) to the at least one base magnet, such that rotation of the at least one base magnet by the motor operates to rotate the at least one agitator magnet and the agitator.
Patent CA-3225337-A1 (CA)
Title: Profils metabolomiques pour la prediction d'un resultat neurologique fonctionnel ou d'un deces suite a une lesion cerebrale traumatique grave
Inventor: WINSTON BRENT
IPC: G01N33/48
Filed: 2022-07-11
Abstract: La présente divulgation concerne une méthode de détermination d'une probabilité d'un résultat favorable ou défavorable, tel que le décès ou un score d?échelle de Glasgow étendue (GOSE) ? 4, chez un sujet présentant une lésion cérébrale traumatique grave (sTBI). La méthode implique l'évaluation quantitative de multiples métabolites peu de temps après la lésion, par exemple le jour 1 et/ou le jour 4, afin de rechercher des changements indiquant un résultat. Une spectrométrie de masse (MS) quantitative ou une spectroscopie par résonance magnétique nucléaire (RMN) du proton (1H) peut être utilisée pour évaluer de multiples métabolites à l'intérieur d'un seul échantillon de sang en vue d'une comparaison avec un témoin.