baber/WOPTO huggingface dataset:
Patent CA-3115059-A1 (CA)
Inventor: SATPAYEV DAULET KADYL
IPC: C07K16/28
Filed: 2019-10-01
Abstract: Des aspects de l'invention comprennent des compositions et des méthodes pour le traitement de tumeurs solides avec des lymphocytes T ?d modifiés ou non modifiés. Dans certains modes de réalisation, les lymphocytes T ?d comprennent une construction de récepteur d'antigène chimérique (CAR). La construction CAR peut contenir un domaine de liaison anti-TryD, une charnière CD8a et un domaine transmembranaire, un domaine costimulateur, un domaine de signalisation 003?, une combinaison de ceux-ci ou l'ensemble de ceux-ci. La construction CAR peut contenir un domaine de liaison anti-GPC3, une charnière CD8a et un domaine transmembranaire, un domaine costimulateur, un domaine de signalisation CD3?, une combinaison de ceux-ci ou l'ensemble de ceux-ci. La construction CAR peut contenir un domaine codant pour une cytokine de chaîne gamma commune sécrétée telle qu'un domaine sIL 15.
Patent CA-3115772-A1 (CA)
Inventor: PARK SUNG JIN
IPC: A61K38/18
Filed: 2019-10-09
Abstract: The present invention provides methods of screening for proteolytically stable growth factor variants, including, for example variants of human fibroblast growth factor 1 (FGF1). The present invention also provides for FGF1 variants comprising at least one amino acid substitution, an amino acid deletion, an amino acid addition and combinations thereof, wherein the resulting FGF1 variant exhibits increased proteolytic stability as compared to wild-type FGF1, as well as related uses.
Patent CA-3116328-A1 (CA)
Inventor: SIEMIONOW MARIA
IPC: C12N5/078
Filed: 2018-11-28
Abstract: A multi-chimeric cell created by ex vivo fusion of three or more hematopoietic stem cells, mesenchymal stem cells, myoblasts, pericytes, or satellite cells, or a combination thereof, from three or more different donors is provided, as is the use of these cells in thransplant therapy and treatment of immune deficiency and genetic disorders.
Patent CA-3116837-A1 (CA)
Inventor: DUBIEF FLAVIEN
IPC: A23N12/08
Filed: 2019-10-25
Abstract: The invention concerns a method for roasting coffee beans with a roasting apparatus (10) said roasting apparatus being positioned in a room and said roasting apparatus comprising : - a roasting device (1), and - a smoke treating unit (3) configured to treat the smoke produced in the roasting device (1) and to prevent the dispense of air contaminants in the room.
Patent CA-3119086-A1 (CA)
Title: Lactic acid-producing hydrogenophilus bacterium transformant
Inventor: YUKAWA HIDEAKI
IPC: C12N15/53
Filed: 2018-11-30
Abstract: A transformant, which is obtained by introducing into a bacterium of the genus Hydrogenophilus (a) a lactate dehydrogenase gene and/or (b) a malate/lactate dehydrogenase gene, can efficiently produce lactic acid with the use of carbon dioxide as a sole carbon source. From the viewpoint of high lactic acid production efficiency, ldh genes of Parageobacillus thermoglucosidasius, Geobacillus kaustophilus and Thermus thermophilus are preferred among lactate dehydrogenase genes, and mldh gene of Thermus thermophilus and mldh-1 and mldh-2 genes of Meiothermus ruber are preferred among malate/lactate dehydrogenase genes.
Patent CA-3120840-A1 (CA)
Inventor: BEHZADPOUR FOROUZAN
IPC: B64C1/06
Filed: 2021-06-02
Abstract: A wing assembly includes a center wing structure and a pair of outer wing structures.  The center wing structure includes a center wing front spar, a center wing rear spar, and an engine mounting location on each side of a wing centerline. Each outer wing structure includes an outer wing front and rear spar configured to be coupled respectively to the center wing front and rear spar to define a wing joint coupling the outer wing structure to the center wing structure. The center wing structure is configured such that the spar terminal ends of the center wing front and rear spars at each wing joint are located no further inboard than an engine centerline associated with the engine mounting location, and no further outboard of the engine centerline than ten percent of a distance between the engine centerline and the wing centerline.
Patent CA-3121571-A1 (CA)
Title: Plate between ring assemblies of a ring seal system
Inventor: JONES BENJAMIN
IPC: F16J15/34
Filed: 2019-11-18
Abstract: The ring seal system may include a second ring assembly (206-2) that includes a second sealing surface. The ring seal system may include a plate (214), between the first ring assembly and the second ring assembly, that includes a first contact surface and a second contact surface. The ring seal system may include a coating on the first contact surface and the second contact surface. The first contact surface may be mechanically connected to the first sealing surface to form a first seal with the first sealing surface. The second contact surface may be mechanically connected to the second sealing surface form a second seal with the second sealing surface.
Patent CA-3123536-A1 (CA)
Inventor: NEER KIRK
IPC: E03F5/22
Filed: 2021-06-29
Abstract: Un accessoire broyeur est utile pour une pompe dans une application deaux usées. Laccessoire broyeur a une plaque de fragmentation et un corps de fragmentation qui coopèrent sur des solides, surtout des solides fibriformes. La plaque de fragmentation a une première et une deuxième surface plane montées dans une entrée de la pompe, avec une pluralité de trous débouchants et une ouverture centrale. Le corps de fragmentation est suspendu sur le dessus de la première surface plane, et il sétend à travers louverture centrale pour coupler, de manière rotationnelle, avec un arbre d'entraînement de la pompe. Un point central du corps de fragmentation a une pluralité de bras qui sétendent, de manière radiale, à proximité de la première surface plane de sorte quun bord d'attaque des bras interagit avec les trous débouchants sur des solides qui les traversent. Un logement définit une chambre de fragmentation autour de la plaque de fragmentation et du corps de fragmentation pour les protéger et pour induire un mouvement de tourbillonnement.
Patent CA-3123880-A1 (CA)
Title: Extended reality ride test assembly for amusement park system
Inventor: GRAHAM MARTIN EVAN
IPC: A63G7/00
Filed: 2020-01-02
Abstract: An amusement park attraction includes a ride vehicle (150) configured to travel along a path (152) of the amusement park attraction, an attraction controller (107) configured to generate virtual elements, and a robot assembly (108) disposed on the ride vehicle (150). The head (170) of the robot assembly (108) is configured to adjust positions relative to the ride vehicle (150). The amusement park attraction further includes a headset (106) communicatively coupled to the attraction controller (107) and a camera (122) disposed in the head (170) of the robot assembly (108). The headset (106) is configured to be disposed on the head (170) of the robot assembly (108). The headset (106) is also configured to display the virtual elements generated by the attraction controller (107) based on a headset position in the amusement park attraction. The camera (122) is configured to acquire data indicative of the virtual elements displayed by the headset (106).
Patent CA-3124662-A1 (CA)
Title: Conveyor belt
Inventor: ISHIBASHI YUSUKE
IPC: B65G15/42
Filed: 2019-09-25
Abstract: A conveyor belt 10 is formed by covering a belt core 14 with cover rubber 12. The cover rubber 12 is configured such that at least a portion of the surface thereof has a micro-asperity structure, and as a result of the micro-asperity structure, the surface roughness is 1 µm to 12 µm, the sharpness is 2 to 9, and the specular gloss with an incident angle of 60° is 0.1 to 10. In particular, it is preferable that the surface roughness be 2 µm to 5 µm, that the sharpness be 3 to 5, and that the specular gloss with an incident angle of 60° be 0.1 to 3. Due to this configuration, the conveyor belt 10 is less likely to have external appearance defects resulting from bloom.
Patent CA-3125419-A1 (CA)
Inventor: MOHAMMED MANSOOR
IPC: G16H50/30
Filed: 2021-07-21
Abstract: A system for providing intervention information to a subject may be configured to perform a method including: receiving, via the processor, genetic information of the subject, the genetic information including a plurality of sets, and each set comprising one or more genes; assigning, via the processor, a value to each respective set;  assigning, via the processor, a respective classification to the subject in one or more categories, wherein: each category corresponds to a respective set; and the assignment of the respective classification is based on the respective values assigned to the respective sets; obtaining, via the processor, health profile information and wellness intervention information associated with the assigned classifications of the one or more categories; and outputting, via the processor, the health profile information and the wellness intervention information to a user. The assignment of the respective classification may be predictive of the health state of the subject, and a method may include: generating a health profile of the subject based on the predicted health state from the assigned classifications for the one or more categories; and outputting the health profile of the subject.
Patent CA-3125473-A1 (CA)
Inventor: LIPORAZZI FABIAN DARIO
IPC: A47G23/06
Filed: 2021-07-21
Abstract: A disposable tablecloth for a tray is provided that covers the handles of the tray. The tablecloth is provided with transverse perforated folding lines, which delimit surfaces, and when folded, generate the insert to place the handles.
Patent CA-3126981-A1 (CA)
Inventor: CONRAD WAYNE ERNEST
IPC: A47G25/02
Filed: 2021-08-05
Abstract: Il est décrit un appareil de suspension de vêtement ou déquipement sportif pouvant être installé de manière amovible dans un débarras darmoire et étant reconfigurable dune position fermée dans laquelle lappareil est généralement plat pour le transport, et une position de fonctionnement ouverte dans laquelle de multiples emplacements sont fournis pour suspendre du vêtement ou de léquipement sportif.
Patent CA-3128104-A1 (CA)
Inventor: GU XIAOLING
IPC: A61P29/00
Filed: 2020-01-31
Abstract: L'invention concerne un anticorps anti-PD-1, un fragment de liaison à l'antigène de celui-ci, et une utilisation pharmaceutique associée. En particulier, l'invention concerne un anticorps anti-PD-1 humanisé contenant une région CDR spécifique et un fragment de liaison à l'antigène de celui-ci, une composition pharmaceutique contenant l'anticorps anti-PD-1 et son fragment de liaison à l'antigène, ainsi qu'une utilisation de celui-ci en tant que médicament. Plus particulièrement, la présente invention concerne l'utilisation d'un anticorps anti-PD-1 humanisé dans la préparation d'un médicament pour le traitement de maladies ou de troubles associés à PD-1.
Patent CA-3129194-A1 (CA)
Inventor: TJOM KYRRE J
IPC: G01C13/00
Filed: 2020-01-29
Abstract: La présente invention concerne un procédé de détermination d'un profil de vitesse de courant d'eau dans une colonne d'eau par enregistrement d'un écart entre une première position et une seconde position d'un véhicule subaquatique qui se déplace dans la colonne d'eau. Un ensemble de véhicules subaquatiques est déployé, à partir d'un navire en surface, dans l'eau. Le ou les véhicules se dirigent vers la première position, qui, pour le premier ensemble, est une position estimée prédéfinie (PEP). Le véhicule enregistre, par l'intermédiaire de premiers moyens, la seconde position, qui est la position réelle (AP). La différence (??) entre la position estimée prédéfinie (PEP) et la position réelle est enregistrée et, sur la base de la différence, un ensemble de données d'écart est calculé. Un profil de courant mis à jour ou une série de vitesses de courant d'eau horizontale (UV) est déterminé.
Patent CA-3132098-A1 (CA)
Inventor: KOWALCHUK TREVOR LAWRENCE
IPC: A01C7/08
Filed: 2021-09-27
Abstract: An opener configured to be coupled to an agricultural implement is provided.  The opener includes a first passage configured for pneumatic delivery of a first agricultural product. The first passage is defined by a first wall. The first passage includes a first outlet for the first agricultural product. The opener also includes a second passage configured for singulated delivery of a second agricultural product.  The second passage is defined by a second wall. The second wall of the second passage is disposed within the first wall of the first passage.
Patent CA-3132644-A1 (CA)
Inventor: ENGUEHARD MARCEL PAUL SOSTHENE
IPC: G06F9/455
Filed: 2020-04-02
Abstract: La présente invention concerne des systèmes, procédés et supports d'informations lisibles par ordinateur permettant d'utiliser une affinité de service en vue d'un placement d'applications. Un procédé consiste à évaluer, à l'aide d'un module NetFlow à l'intérieur d'un orchestrateur, des flux entrant et sortant de services déployés à l'intérieur d'un réseau multi-nuds pour produire une évaluation. En fonction de l'évaluation, le procédé consiste à déterminer une affinité entre des services respectifs des services déployés pour produire une matrice de trafic et, en fonction de la matrice de trafic, au niveau d'un module de placement, à déterminer sur quels nuds à l'intérieur du réseau multi-nuds il convient de placer une ou plusieurs applications. La détermination de l'affinité peut être effectuée à au moins un premier niveau et un second niveau. Le premier niveau peut comprendre un niveau de conteneur ou de machine virtuelle individuel(le) et le second niveau peut comprendre un niveau de description de service.
Patent CA-3135684-A1 (CA)
Inventor: BROWN MATTHEW
IPC: G01N23/20
Filed: 2020-03-25
Abstract: A method of non-destructive detection of surface and near surface abnormalities in a metallic product. The method comprises positioning a sample having a surface under a source of an incident radiation. The surface of the sample is then irradiated with the incident radiation from the source. A scattered radiation is detected and a radiation pattern from the detected scattered radiation is produced. Said radiation pattern is then analysed and the output indicative of the scattered radiation from the sample is produced. Said produced output is then compared with a threshold value, the threshold value indicative of a maximum acceptable detected surface abnormality. Finally, the presence of a surface abnormality is identified when the output exceeds the threshold value.
Patent CA-3136872-A1 (CA)
Title: New adeno-associated virus (aav) variants and uses thereof for gene therapy
Inventor: ZUCMAN-ROSSI JESSICA
IPC: C12N15/861
Filed: 2020-04-23
Abstract: Adeno-associated virus (AAV) is a defective mono-stranded DNA virus, endemic in human population (35-80%). Recurrent clonal AAV2 insertions are associated with the pathogenesis of rare human hepatocellular carcinoma (HCC) developed on normal liver. The aimed of the inventors was to characterize the natural history of AAV infection in the liver. Viral DNA was thus quantified in tumor and non-tumor liver tissues of 1461 patients. Presence of episomal form and viral mRNA expression were analyzed using a DNAse/TaqMan based assay and quantitative RT-PCR. In silico analyses using viral capture data explored viral variants and new clonal insertions. AAV DNA was detected in 21% of the patients equally distributed in 2 major viral subtypes: one similar to AAV2, the other hybrid between AAV2 and AAV13 sequences. Thus the inventors provided an integrated analysis of the wild type AAV infection in the liver with the identification of viral genotypes, molecular forms, helper virus relationship and viral integrations. These findings are important to understand wild type AAV biology and particularly relevant considering the large usage of AAV vector in liver-targeted gene therapy. Thus, the present invention relates to new adeno-associated virus (AAV) variants and uses thereof for gene therapy.
Patent CA-3143173-A1 (CA)
Title: System and method for removing noise and/or artifacts from an oct image using a generative adversarial network
Inventor: GALEOTTI JOHN
IPC: G06T5/00
Filed: 2020-06-12
Abstract: Systems, methods, and computer program products are provided for removing noise and/or artifacts from an image. The method includes training a generative adversarial network (GAN) based on a plurality of images, the plurality of images comprising at least one undesired element comprising at least one of the following: noise, speckle patterns, artifacts, or any combination thereof, and generating a modified image based on processing an image of an eye or other object with the GAN to remove the at least one undesired element from the image that is above an outer surface of the eye or other object.
Patent CA-3144884-A1 (CA)
Title: Method for preparing an elastomer from a hydroxylated fatty acid and elastomer obtained by such a method
Inventor: BAKAN BENEDICTE
IPC: C08G63/06
Filed: 2020-06-23
Abstract: The invention relates to a method for preparing a polymer of the elastomer type based on a monomer selected from polyhydroxylated fatty acids and the esters of a polyhydroxylated fatty acid and a C1-C18 aliphatic chain alcohol. This method comprises preparing a reaction medium by mixing the monomer with a polyol, this reaction medium being catalyst free, then a step of heating the reaction medium in order to implement the copolymerisation of the monomer and of the polyol and the cross-linking of the polymer thus formed, with at least the initial phase of this heating state being implemented at a reduced pressure.
Patent CA-3146511-A1 (CA)
Inventor: BIRKNER SASCHA
IPC: A61B3/14
Filed: 2020-09-18
Abstract: L'invention concerne des systèmes et des procédés de suivi de la position et de l'état d'un oeil pendant une procédure ophtalmique, comprenant un dispositif ophtalmique configuré pour mesurer les caractéristiques d'un oeil, un dispositif de suivi de l'oeil configuré pour capturer un flux d'images de l'oeil, et un dispositif logique configuré pour analyser le flux d'images afin de déterminer si l'oeil est fixé sur un objet cible, détecter une séquence de clignements prédéterminée dans le premier flux d'images, retarder pour une période de stabilisation de larme prédéterminée, démarrer un intervalle de film lacrymal stable, et pendant l'intervalle de film lacrymal stable, capturer au moins une mesure de l'oeil à l'aide du dispositif ophtalmique lorsque l'oeil est en train de fixer. La séquence de clignement peut comprendre une pluralité de clignements successifs et la détection de la séquence de clignements peut comprendre le traitement des images à travers un réseau neuronal entraîné pour détecter un oeil ouvert et/ou un oeil fermé.
Patent CA-3146559-A1 (CA)
Inventor: ELIAS STEPHEN PAUL
IPC: G01V3/12
Filed: 2020-07-08
Abstract: Un système de capteur pour déterminer l'occupation dans un espace comprend généralement un dispositif radio émetteur qui transmet des signaux radio sur un canal dans l'espace ; un dispositif radio récepteur qui reçoit les signaux radio transmis qui ont traversé l'espace ; et au moins un processeur mettant en uvre un algorithme centré sur l'occupation qui détermine l'occupation dans l'espace sur la base des signaux radio. Le ou les processeurs déterminent des informations d'état de canal sur la base des signaux radio transmis sur le canal, déterminent l'occupation dans l'espace sur la base des informations d'état de canal, et délivre un signal d'occupation sur la base de l'occupation déterminée.
Patent CA-3146905-A1 (CA)
Title: System and method for machine learning architecture for out-of-distribution data detection
Inventor: WU GA
IPC: G06N3/02
Filed: 2022-01-27
Abstract: Systems and methods for machine learning architecture for out-of-distribution data detection. The system may include a processor and a memory storing processor-executable instructions that may, when executed, configure the processor to: receive an input data set;  generate an out-of-distribution prediction based on the input data set and an auto-encoder, the auto-encoder trained based on a pretext task including a transformation of one or more training data sets for reconstruction, the trained auto-encoder trained for reducing a reconstruction error to encode semantic meaning of the training data sets; and generate a signal for providing an indication of whether the input data set is an out-of-distribution data set.
Patent CA-3146969-A1 (CA)
Inventor: NUSSBAUM DAVID
IPC: G03H1/04
Filed: 2020-12-04
Abstract: A holographic display device for presenting a hologram-like image and a method of use are disclosed. The holographic display device includes a box-like structure, a translucent panel, and light panels extending the entire length of the box-like structure. The light panels position between the box-like structure and the translucent panel. The holographic display device includes a transparent monitor connecting the box-like structure at its front end. The transparent monitor receives and displays an image. The light panels illuminate light and the translucent panel diffuses, blends, and evenly distributes the light in the interior. Transmitted shadowing to the monitor provides a realistic appearance. A unique image capturing system for capturing the image to be displayed on the transparent monitor is also disclosed. The image capturing system transmits the image to the holographic display device in real-time or as a pre-recorded image using wired or wireless protocols.
Patent CA-3147481-A1 (CA)
Inventor: WONG PETER S
IPC: B60N2/24
Filed: 2022-02-02
Abstract: Seating in a passenger compartment of a vehicle comprises a first base in the passenger compartment of the vehicle. First and second apertures are disposed on opposite ends of the first base. A modified first base having third and fourth apertures is located adjacent the first base. A first rod is disposed in the first and third apertures. A second rod is disposed in the second and fourth apertures. A seat module has an end support including a fifth aperture for accepting the first rod. An opening is disposed on the end support for accepting the second rod.
Patent CA-3147664-A1 (CA)
Title: Systems and methods for improved lap shear strength and displacement of two-component structural adhesives
Inventor: KRILEY JOSEPH P
IPC: C23C22/34
Filed: 2020-06-23
Abstract: Disclosed are systems for treating a substrate comprising a deoxidizing composition and a coating composition. The deoxidizing composition comprises a Group IVA metal and/or a Group IVB metal and free fluoride, optionally may comprise a homopolymer or copolymer comprising a phosphorous-containing monomeric subunit, and has a pH of 1.0 to 3Ø The coating composition comprises first and second components and elastomeric particles. The first component comprises an epoxy-containing compound (E1) and/or an epoxide-functional adduct (E2). The second component comprises a diamine and/or a polyamine comprising a cyclic ring (A2) and/or an amine-functional adduct (A3). The present invention is also directed to methods of making the compositions, methods of coating a substrate, and coated substrates.
Patent CA-3147669-A1 (CA)
Inventor: GUSSERT CORY P
IPC: B65H18/28
Filed: 2020-08-07
Abstract: L'invention concerne une ligne de traitement traitant des blocs de matériau en bande enroulée concentriquement et comportant des sections amont et aval. Un accumulateur principal comporte des godets qui reçoivent, qui maintiennent et qui libèrent les blocs. Un alimenteur d'entrée reçoit les blocs de la section amont et les transporte jusqu'à un godet d'accumulateur principal. Un chargeur comporte un accumulateur de chargeur et des godets de chargeur qui reçoivent, qui maintiennent et qui libèrent les blocs. Un transporteur de transfert, situé entre l'accumulateur principal et le chargeur, reçoit un bloc du godet d'accumulateur principal et transporte le bloc jusqu'à un godet chargeur, indépendamment de l'alimenteur d'entrée. Le chargeur reçoit un bloc du transporteur de transfert. Le chargeur transporte le bloc dans le godet chargeur jusqu'à une évacuation du chargeur. L'évacuation de chargeur évacue le bloc du godet chargeur à la section aval de la ligne de traitement.