baber/WOPTO huggingface dataset:
Patent EP-1196193-B1 (EP)
Inventor: DONDERO RICHARD S
IPC: A61P37/04
Filed: 2000-12-04
Granted: 2008-11-05
Abstract: The present invention concerns compositions comprising an IL-1 mutein that is useful as an adjuvant for stimulating a controlled immune response when administered to a human or animal. For example, muteins of IL-1beta can be used according to the invention. The mutein composition can include a vaccine antigen, such as whole inactivated or attenuated virus, recombinant or synthetic peptides, and other antigenic materials. The present invention also pertains to the use of an IL-1 mutein in a human or animal as an adjuvant to increase immune responses to an antigen or other material to which an immune response is desired.
Patent EP-1208116-B1 (EP)
Inventor: LISTER-JAMES JOHN
IPC: A61P35/04
Filed: 2000-08-23
Granted: 2008-04-30
Abstract: The invention provides novel peptide-based pharmacophores and compounds which bind somatostatin receptors with high affinity and which exhibit improved pharmacokinetic properties over known somatostatin analogs. The pharmacophores and compounds of the invention may be used in labeled or unlabeled form for diagnosing and/or treating somatostatin responsive diseases. The invention also provides radiopharmaceuticals and kits comprising these compounds, as well as methods for diagnosing and/or treating somatostatin receptor mediated diseases.
Patent EP-1237751-B1 (EP)
Inventor: VALENTIN ERHARD
IPC: B60R13/08
Filed: 2000-12-06
Granted: 2006-03-08
Abstract: The invention relates to an accoustically active sound proofing component embodied as a mass-spring system. The spring is constructed of a two-component polyurethane foam made of polyol and isocyanate. The mass is comprised of an insulating layer with or without a carpet covering, whereby the spring has at least one locally defined region. The proportion of polyol to isocyanate in the reaction mixture is different to that of the bordering areas. The invention also relates to a method for the production of one such sound proofing component.
Patent EP-1154236-B1 (EP)
Inventor: KNOLL ALEXANDER DR
IPC: G01C23/00
Filed: 2001-05-08
Granted: 2009-05-06
Abstract: The aircraft display for orientation of a pilot on approach to a target or runway (13). The display comprises an aircraft symbol with a middle line depicting the longitudinal axis of the plane and a perpendicular line to indicate the angle of bank. A target symbol has a reference line and a position symbol. A horizontal line turns with the aircraft symbol when the aircraft turns around its longitudinal axis. The target symbol is arranged at a distance from the center of the display with its reference line having the center at a reference point and with the horizontal line also passing through the center. The target symbol turns around the reference point, dependent on the relative alignment of the aircraft actual direction to the aircraft destination target point.
Patent EP-1158139-B1 (EP)
Inventor: JONES PETER J
IPC: G01N33/28
Filed: 2001-05-22
Granted: 2006-07-26
Abstract: In the pyrolytic oil-production index method, or POPI method, the numerical values obtained by the application of the prior art POPI method are standardized or normalized. In another aspect, the POPI method and associated data are employed in combination with other empirically determined information to provide values of (1) the API gravity for the reservoir oil; (2) the Apparent Water Saturation (AS W ) of the reservoir rock; and (3) the cementation and saturation exponents that are used in the Archie equation for calculating the water saturation in the oil-reservoir rock. This method results in the standardization of the numerical values derived by the POPI method. Applying the normalization or standardization process to the POPI method results in the conversion of the numerical value of POPI O  for good oil-producing reservoir rock to a standard value.
Patent EP-1216806-B1 (EP)
Inventor: MANUEL MARK
IPC: B23P15/24
Filed: 2001-12-20
Granted: 2009-06-03
Abstract: An apparatus 10 and a method 50 for the creation of a tool 40. The apparatus 10 and the method 50 allow for dynamic measurement of the tool 40 as it is being created and further allows for the use of positive feedback to increase the likelihood that the produced tool will be structurally similar to a certain model. The apparatus 10 and method 50 further allow sections of varying thicknesses to be used and provide a technique to create surfaces which further increase the likelihood that the produced tool will be structurally equivalent to a desired and modeled tool. <IMAGE>
Patent EP-1354967-B1 (EP)
Inventor: SAKAI TAKAYUKI
IPC: F27D99/00
Filed: 2001-12-18
Granted: 2006-05-10
Abstract: There is provided a heat treatment unit which uses a multi-layered heat treatment furnace (1) comprising a layer of fluidized bed (2) composed of particles and another layer of atmosphere layer (3) composed of gases, the former being excellent in thermal efficiency and uniformity of heat distribution and the latter being positioned in the free board section over the fluidized bed (2), in which these layers operate at temperature levels different from each other, and the work piece is heat-treated by being partly immersed in the fluidized bed (2) having a given temperature with the other part being exposed in the atmosphere layer (3) also operating at a given temperature, according to desired mechanical properties of the work piece at each position. This heat treatment unit is improved from the conventional one in that it can give desired mechanical properties which are required by each part of metallic work requires without increasing the investment cost. <IMAGE>
Patent EP-1310295-B1 (EP)
Inventor: MELAAEN INGRID S
IPC: C08F2/01
Filed: 2001-10-30
Granted: 2007-07-18
Abstract: A settling leg for a polymerisation reactor connected to the lower part of a loop reactor 1. A conduit 2 is welded to the loop reactor and leads to upper block valve 3 and lower block valve 4. Downstream of the lower block valve 4 is a further conduit 5 which leads to a lower region 6 and to a product take off (PTO) valve 7. Conduit 5 has a significantly greater cross-sectional area than conduit 2. In use, the block valves 3 and 4 are always open to allow slurry from the reactor loop to enter the settling leg. The PTO valve 7 is regularly opened to allow the settled polyethylene 'fluff' to be rapidly expelled along conduit 8. The greater area of conduit 5 significantly increases the settling rate and polymer concentration of the polyethylene 'fluff'. <IMAGE>
Patent EP-1182303-B1 (EP)
Title: Cleaning and deodorising device for a toilet bowl
Inventor: ZANARDI ANDREA
IPC: E03D9/03
Filed: 2001-08-17
Granted: 2005-10-19
Abstract: The flushing additive dispenser for a water closet has an additive tank (1) connected to a tray (4) and with suspension mountings for attachment to a toilet bowl. The dispenser has a passage from an outlet (2) for the tank to discharge the additive, and piping. The passage allows additive flow and air flow from the tank. The piping is mounted on a horizontal wall of the tray. Claims include a tank for the dispenser
Patent EP-1248588-B1 (EP)
Inventor: WANEK ERICH
IPC: A61K6/891
Filed: 2001-01-15
Granted: 2005-05-11
Abstract: The invention relates to preparations, containing (A) 30 to 56 wt.-% aziridino polyethers with a cyclic polyether content lower than 5.0 wt.-%; (B) 30 to 45 wt.-% compounds which effect a softening of the cured dental materials; (C) 10 to 15 wt.-% filler; (D) 4 to 10 wt.-% further active ingredients; with the provisos that the weight ratio between constituents (A) and (C) to the compounds of constituent (B) is 1.2 to 2.1; constituent (B) consists of compounds with molar masses lower than 500 g/mol (B1) and of trisacylesters of glycerol of non-animal origin with molar masses between 500 to 2000 g/mol (B2) as well as of compounds with molar masses greater than 2000 g/mol (B3) and the weight ratio between (B1) and (B3) is 1:0.8 to 1:2.3, as well as their use.
Patent EP-1339415-B1 (EP)
Inventor: CHOI SOO-IL
IPC: A61P15/00
Filed: 2001-01-03
Granted: 2007-03-21
Abstract: Disclosed are a multipurpose, high-functional, alkaline solution composition, preparation therefor and use thereof as a nonspecific immunostimulator. The composition comprises 1-25 parts by weight of borax (Na<SUB>2</SUB>B<SUB>4</SUB>O<SUB>7</SUB>.10H<SUB>2</SUB>O), 10<SUP>-5</SUP>-10<SUP>-4 </SUP>parts by weight of sodium thiosulfate (Na<SUB>2</SUB>S<SUB>2</SUB>O<SUB>3</SUB>.5H<SUB>2</SUB>O), 30-150 parts by weight of potassium carbonate, 30-200 parts by weight of refined sugar (C<SUB>12</SUB>H<SUB>22</SUB>O<SUB>11</SUB>), and 100-200 parts by weight of water, based on 100 parts by weight of sodium metasilicate (Na<SUB>2</SUB>SiO<SUB>3</SUB>.5H<SUB>2</SUB>O). In addition to bringing about an improvement in disease resistance, weight gain rate, crop yield, crop quality, harvest time, the composition shows nonspecific immunostimulating activities, including antibody production and immune enhancement, by activating immune cells, thereby maximizing vaccination effects on malignant viral diseases.
Patent EP-1255919-B1 (EP)
Inventor: OBERHARDT STEPHAN
IPC: F02B27/04
Filed: 2001-02-07
Granted: 2005-11-09
Abstract: An exhaust pulse control unit (10) for increasing exhaust manifold vacuum in an engine comprises an inlet (11), an outlet (12) and an intermediate containment zone (13). An exhaust pulse capture and expansion zone (14) is located between the inlet and intermediate zone and a merging zone (17) between the intermediate zone and the outlet. The capture and expansion zone may consist of two stages with the first stage providing a relatively rapid increase in exhaust gas volume.
Patent EP-1254240-B1 (EP)
Title: Protease hybride produisant une reponse immunogene reduite et procedes d'utilisation de cette protein.
Inventor: ESTELL DAVID A
IPC: C12N9/00
Filed: 2001-01-22
Granted: 2007-02-28
Abstract: La présente invention concerne de nouveaux procédés et de nouvelles compositions permettant de produire des compositions hyperallergéniques et hypoallergéniques. De manière spécifique, la présente invention consiste à neutraliser ou réduire le pouvoir des lymphocytes T de reconnaître des épitopes et permet ainsi d'empêcher la sensibilisation d'un individu à la protéine. En variante, des épitopes de lymphocytes T sont modifiés, afin de produire des réactions immunogènes plus importantes. La présente invention concerne également des protéines naturelles.
Patent EP-1294906-B1 (EP)
Inventor: YANG MENG
IPC: C12Q1/6897
Filed: 2001-03-19
Granted: 2009-01-21
Abstract: The invention relates to the whole-body external optical imaging of gene expression. Specifically, methods for whole-body external optical imaging of gene expression and methods for evaluating a candidate protocol or drug for treating diseases or disorders using a fluorophore operatively linked to the promoter of a gene and external optical imaging are provided herein. Methods to screen for substances or genes that regulate target promoters are also provided.
Patent EP-1274729-B1 (EP)
Inventor: BENDER ECKHARD
IPC: A61P25/04
Filed: 2001-04-02
Granted: 2008-04-02
Abstract: The invention provides nucleic acid encoding a G protein coupled receptor (adenine binding GPCR) with specificity for adenine, isolated adenine binding GPCR, assay and treatment methods utilising the same.
Patent EP-1283994-B1 (EP)
Inventor: MEHTA MEHUL
IPC: G06F9/445
Filed: 2001-05-25
Granted: 2004-07-14
Abstract: La présente invention concerne un gestionnaire de reconfiguration destiné à un système reconfigurable. Le gestionnaire de reconfiguration comprend un pilote de reconfiguration (62) qui reçoit des instructions de reconfiguration d'une autorité supérieure (64); un pilote de signalisation de contrôle d'exécution (72) chargé de mettre en oeuvre la reconfiguration du système reconfigurable; et un pilote de surveillance d'exécution et d'état (74) qui met en oeuvre des demandes d'état concernant le système reconfigurable et lit les accusés de réception et les informations d'état à partir du système reconfigurable. L'invention concerne également un procédé de reconfiguration d'un système reconfigurable comprenant plusieurs modules logiciels. Dans ledit procédé, le gestionnaire de reconfiguration (20) reçoit une demande de reconfiguration de l'autorité supérieure (64), négocie la demande de reconfiguration avec l'autorité supérieure (64), effectue un contrôle de capacité en se référant à une liste de propriétés pour s'assurer que le système reconfigurable peut fonctionner conformément à la reconfiguration négociée; l'autorité supérieure (64) donne au gestionnaire de reconfiguration (20) l'instruction de reconfigurer une liste de modules logiciels; le gestionnaire de reconfiguration (20) crée une version reconfigurée du système reconfigurable en ordonnant la reconfiguration des modules logiciels; et le système reconfigurable devient le système actif et la configuration antérieure du système reconfigurable devient obsolète.
Patent EP-1287717-B1 (EP)
Inventor: LUCIDARME THIERRY
IPC: H04L12/28
Filed: 2001-05-18
Granted: 2007-09-26
Abstract: The invention concerns a cellular radiocommunication system comprising a network core (21) including switches (28, 30, 32), one or several gateways (28, 32) to external networks, subscriber management means (33) and billing management means (34, 35). Several radio access networks (22, 40), including each base stations (24, 42) capable of radio communication with mobile stations (23), are connected to the network core switches. Said radio access networks include an access network (22) managed with the network core by a cellular operator and at least an additional access network (40) having a substantially less extensive radio coverage and a substantially wider bandwidth than the one managed by the cellular operator. When setting up a communication with a mobile station through the network core and one of the access networks, a report message is generated specifying the access network concerned.
Patent EP-1294592-B1 (EP)
Inventor: WELZ SIEGFRIED
IPC: B60R21/26
Filed: 2001-06-21
Granted: 2005-03-02
Abstract: Abstract of Disclosure A cold gas generator for an airbag system has a storage device filled with a gas under pressure and provided with a  gas outlet opening. A thin-walled sealing disk is provided which, in a rest state, seals pressure-tightly the gas outlet opening. A support device supports the sealing disk against a gas pressure of the gas acting on the sealing disk in a pressure direction. A triggering device acts on the support device. The support device has a pressure plate resting against the sealing disk and a support lever supporting the pressure plate and the sealing disk. The pressure plate and the support lever are configured as separate parts. A bearing supports  the support lever such that the support lever receives forces in the pressure direction and is force-free transversely to the pressure direction. The triggering device acts on the support lever so as to cause pivoting about the bearing.
Patent EP-1303438-B1 (EP)
Inventor: SCHWINDT MICHAEL
IPC: B63C9/26
Filed: 2001-07-06
Granted: 2005-11-09
Abstract: The invention relates to a method and a device for saving people in distress in the sea. Said device consists of a hawser which forms a hauling line with a sling fastened thereto, said sling being placed around the body of the person in distress in the sea. The aim of the invention is to provide a method, using simple means, of pulling the person in distress by means of the hauling line on the surface of the water, up to the crane hook that is located immediately above the surface of the water and of then fixing the hauling line to the crane hook, in such a way that said line cannot be paid back out and that the crane lifts the person in distress out of the water onto the deck by raising the crane hook. In other words: the invention aims to provide a connecting member between the crane hook and the rescue sling, which pulls said rescue sling by the hauling line up to the crane hook, so that it can be lifted out of the water and on board by the crane. The invention is characterised by the provision of a guiding or blocking device for the hauling line. Said device can be suspended on a lifting unit and is equipped with guide rollers for the hauling line, a support device for the guide rollers, a coupling device for the lifting unit and a hauling line brake which acts in the direction of operation and can be deactivated.
Patent EP-1312820-B1 (EP)
Inventor: TODA KAZUTOSHI
IPC: B60B35/18
Filed: 2001-08-13
Granted: 2007-08-01
Abstract: A bearing device, comprising a shaft body having an axial cylindrical part at the free end side thereof and rolling bearings fitted onto the outer peripheral surface of the shaft body, wherein the cylindrical part is bucklingly deformed in radial outer direction by a rolling caulking to be caulked to the outer end faces of the inner rings incorporated in the rolling bearings, and the roughness of the inner peripheral surface is set to 12.5 νm or below by 10-point average roughness (Rz).
Patent EP-1322215-B1 (EP)
Inventor: PLATT BEN C
IPC: A61F9/00
Filed: 2001-09-26
Granted: 2008-04-16
Abstract: A method and instrument to irradiate a light adjustable lens, for example, inside a human eye, with an appropriate amount of radiation in an appropriate pattern by measuring aberrations in the system containing the lens; aligning a source of the modifying radiation so as to impinge the radiation onto the lens in a pattern that corresponds to the aberration; and controlling the quantity of the impinging radiation whereby to decrease the aberration. The quantity of the impinging radiation is controlled by controlling the intensity and duration of the irradiation. The pattern is controlled and monitored while the lens is irradiated.
Patent EP-1330464-B1 (EP)
Inventor: BOAZ NEIL WARREN
IPC: C07D205/08
Filed: 2001-09-28
Granted: 2005-11-16
Abstract: Disclosed are substantially enantiomerically pure bis-phosphine compounds comprising a substantially enantiomerically pure chiral backbone linking two phosphine residues wherein one of the phosphine residues has three phosphorus-carbon bonds and the other phosphine residue has two phosphorus-carbon bonds and one phosphorus-nitrogen bond wherein the nitrogen is part of the chiral backbone. The compounds, which have exhibited surprising air stability, are useful as ligands for metal catalysts for asymmetric reactions and have demonstrated excellent results, in particular as rhodium complexes for asymmetric hydrogenation of enamide, itaconate, and alpha-ketoester compounds. Also disclosed are novel processes for the preparation of the bis-phosphine compounds and novel intermediate compounds useful in the preparation of the bis-phosphine compounds.
Patent EP-1353812-B1 (EP)
Inventor: LEFAURE PHILIPPE
IPC: B60C23/04
Filed: 2001-12-04
Granted: 2005-05-18
Abstract: La présente invention concerne un procédé de localisation automatique des roues d'un véhicule automobile. Ce procédé comporte les étapes suivantes: - émission par l'unité roue (12a à 12d) de signaux hautes fréquences représentatifs, au moins, de la pression de la roue sur laquelle l'unité roue est montée, ainsi que d'un code identifiant cette roue, - réception par l'unité centrale (11) des signaux hautes fréquences émis par l'unité roue, le dit procédé étant caractérisé en ce qu'il comporte en outre les étapes suivantes: - émission d'un signal basses fréquences par un moins un dispositif d'émission (14, 14') monté sur le véhicule à proximité des roues selon une position prédéterminé, de manière à réveiller les unités roues placées à proximité, - réception de ce signal basses fréquences par les unités roue et en réponse, émission d'un signal hautes fréquences par les roues réveillées, le dit signal comportant au moins le code identifiant des roues réveillées, et réception du signal hautes fréquences par l'unité centrale (11 ) et association du code identifiant des unités roues réveillées, à la position du ou des dispositifs d'émission (14, 14').
Patent EP-1358219-B1 (EP)
Inventor: UDDING JAN HENDERIKUS
IPC: C08F4/32
Filed: 2001-12-19
Granted: 2006-06-14
Abstract: The invention relates to peroxide compositions comprising a reactive diluent for the peroxide, wherein the diluent is a component containing one or more vinyl ether group(s) and having a monomeric structure according to formula 1, (A-CH=CH-O)n-R, or being covalently built-in into a suitable resinous compound. In the formula   A   represents hydrogen or an alkyl group with 1-3 C atoms, and individual A groups may be different R   either represents an aliphatic group, optionally branched, with 1-20 C atoms, etc. or represents a polyethylene or polypropylene glycol with 2 to 10 glycol units, etc. and n   is 1, 2, 3 or 4.   The components with one or more vinyl ether group(s) covalently built-in into a suitable resinous compound are obtained by reaction of:   a) a first compound (the HVE-compound) containing at least one hydroxyl group and at least one vinyl ether group, and b) a second compound (the D/HIC-compound), being an isocyanate, reacting with formation of one or more urethane group(s), and c) a third compound (the G/P/HP-compound) chosen from the groups of (1) C2-6 glycols, (2) C5-20 polyols having 2-5 hydroxyl groups and (3) hydroxyl terminated polyester compounds, not being alkyd resins, having 1-5 free hydroxyl groups and from 2-50 monomeric ester units (the G/P/HP-compound), or mixtures thereof.   The invention also relates to the preparation of such compositions and to the use of such reactive diluents for peroxides in radically curing of unsaturated polyester resins for structural applications.
Patent EP-1256011-B1 (EP)
Inventor: HARVEY PAUL R
IPC: G01R33/3415
Filed: 2001-11-19
Granted: 2007-03-21
Abstract: L'invention a trait à un procédé permettant d'obtenir des images IRM dans un champ vertical principal, au moyen d'un schéma de sous-échantillonnage tel que la technique SENSE. L'invention concerne plusieurs agencements de bobines permettant de combiner les avantages de la technique SENSE (acquisition à haute vitesse) et du champ vertical (champ visuel ouvert pour le patient afin d'éviter des sensations de peur et de claustrophobie). Ces agencements de bobines comportent de préférence des bobines papillons et ils sont disposés de telle sorte qu'ils permettent d'avoir accès au patient et de déplacer ce dernier à l'intérieur et à l'extérieur du volume d'imagerie, sans qu'il y ait d'interférences des bobines RF.
Patent EP-1233827-B1 (EP)
Title: Procede pour produire un module de membrane
Inventor: BLAESE DIETER
IPC: B01D71/02
Filed: 2001-11-16
Granted: 2006-10-18
Abstract: La présente invention concerne un procédé de production d'un module de membrane, au moyen d'un outil de formage comprenant un canal d'alimentation en substance céramique, ainsi que plusieurs noyaux de formage, montés selon la direction longitudinale dans le canal d'alimentation. Ces noyaux de formage présentent la section transversale d'un polygone, de préférence d'un hexagone. Ce procédé consiste à comprimer la substance céramique à travers le canal d'alimentation de l'outil de formage, fournissant alors une ébauche de module de membrane comprenant plusieurs canaux de section transversale non circulaire, de préférence hexagonale, puis, après la production de l'ébauche de module de membrane, à recouvrir l'intérieur des canaux par application de barbotine de membrane, produisant alors un canal interne à géométrie approximativement circulaire.
Patent EP-1267125-B1 (EP)
Inventor: HAUSSNER MICHAEL
IPC: F23Q7/00
Filed: 2002-03-04
Granted: 2008-05-21
Abstract: The spark plug has a connecting sleeve (6) attached to the electrode (9) on the supply side. The space between this and the electrode is filled with an insulator (8). An Independent claim is included for a method for making the spark plug.