baber/WOPTO huggingface dataset:
Patent EP-2802578-A1 (EP)
Inventor: GALLEY GUIDO
IPC: C07D471/04
Filed: 2013-01-08
Abstract: The present invention relates to compounds of formula (I) wherein R 1  is a one or two membered heteroaryl group, selected from the group consisting of formula (a), (b), (c), (d), (e), (f), (g), (h), (i), (j); R 2  is hydrogen or halogen; or R 1  and R 2  may form together with the carbon atoms to with they are attached the following rings formula (k), (l), (m), (n), (o). R 3  is hydrogen, halogen or lower alkyl; n is 1 or 2; R 4  is phenyl, optionally substituted by one or two substituents, selected from halogen or cyano, or is pyridinyl, optionally substituted by halogen, or is tetrahydropyran, or is -NH-C(O)-phenyl, optionally substituted by halogen; R 5  is hydrogen or halogen; R 6  – R 13  are phenyl, optionally substituted by halogen: R 14  is –NH-C(O)-phenyl, substituted by halogen; R 15  is hydrogen, lower alkyl substituted by halogen or is halogen; R 16  is hydrogen or lower alkoxy; R 17  is pyridinyl, optionally substituted by lower alkoxy or lower alkyl substituted by halogen; or to a pharmaceutically suitable acid addition salt thereof, to all racemic mixtures, to all their corresponding enantiomers and/or optical isomers and to all tautomeric forms of compounds of formula I. The compounds of formula I have a good affinity to the trace amine associated receptors (TAARs), especially for TAAR1. The compounds may be used for the treatment of depression, anxiety disorders, bipolar disorder, attention deficit hyperactivity disorder (ADHD), stress-related disorders, psychotic disorders such as schizophrenia, neurological diseases such as Parkinson's disease, neurodegenerative disorders such as Alzheimer's disease, epilepsy, migraine, hypertension, substance abuse and metabolic disorders such as eating disorders, diabetes, diabetic complications, obesity, dyslipidemia, disorders of energy consumption and assimilation, disorders and malfunction of body temperature homeostasis, disorders of sleep and circadian rhythm, and cardiovascular disorders.
Patent EP-2847072-A1 (EP)
Inventor: WILLIAMS ROBERT B
IPC: H01Q1/12
Filed: 2013-02-14
Abstract: An inflatable structure mount is used for mounting a device (16) to an inflatable structure (10). An example is mounting of radar panels to an inflatable structure within an airship. The mount includes the device (16), and inserts (32) coupled to the back side of the device (16), which mechanically couple to flexures (22, 24, 26, 28) mounted on the inflatable structure (10). Some of the flexures (22, 24, 26, 28) may have slotted holes (70), used in positioning the inserts (32) on the inflatable structure (10) at positions that will allow the flexures (22, 24, 26, 28) to mate with the inserts (32). A jig or tool may be used as part of the installation process, to locate the flexures (22, 24, 26, 28) at points where they will properly engage the inserts (32). The flexures (22, 24, 26, 28) may also each face a center point that is underneath the device (16) to be mounted. The flexures (22, 24, 26, 28) may engage the inserts (32) in ways that allow for quick installation of devices (16), and may allow for visual inspection of proper installation.
Patent EP-2800684-A1 (EP)
Inventor: ROHWERDER DIRK
IPC: B61D17/12
Filed: 2013-03-05
Abstract: The invention relates to a rail vehicle having a roof region in the longitudinal direction of which an air-conditioning duct is laid and which is bounded with respect to a passenger compartment by means of an inner ceiling, when the air-conditioning duct is composed in its longitudinal direction of at least two air-conditioning duct elements (1) which are connected to one another by means of a sealing frame (9) which can be pre-positioned. Furthermore, a method for constructing a roof region for such a rail vehicle is specified.
Patent EP-2834441-A1 (EP)
Inventor: SAULLO FRANCA
IPC: E06B9/34
Filed: 2013-03-22
Abstract: The device for controlling (1) the slats (2) of a blind with adjustable slats (2) comprises a rotating longitudinal support body (7) of rockers (6) connected by rods (4, 5) opposite each other for the synchronisation of the oscillation thereof, the rods (4, 5) being elastically flexible and the longitudinal support body (7) being longitudinally divided into a plurality of modules (8) along which the rods (4, 5) extend longitudinally.
Patent EP-2828279-A1 (EP)
Title: Procede de ligation native
Inventor: MELNYK OLEG
IPC: C07K7/08
Filed: 2013-03-18
Abstract: La présente invention concerne un procédé de fabrication d'un polypeptide comprenant au moins une étape de ligation native à l'aide d'un peptide fonctionnalisé par un groupement sélénié. L'invention concerne également des peptides et des composés à base de sélénium.
Patent EP-2828837-A1 (EP)
Inventor: STRAMPEL SEBASTIAAN WILLEM
IPC: G08B13/14
Filed: 2013-03-22
Abstract: The invention relates to a method in a theft detection unit wherein the unit is secured to a movable object. The method repeatedly receives acceleration data from a three axes acceleration sensor (4), determines a reference orientation of the three axes acceleration sensor from the acceleration data, determines a difference signal representing a change in angle of the received acceleration data with respect to the reference orientation; and generates a control signal for activating an alarm when the difference signal exceeds a first threshold value for a predefined period of time. The method is very suitable for an object that rolls repeatedly from one side to the other without generating a false alarm due to said regular movement.
Patent EP-2825329-A1 (EP)
Inventor: HAMMERS BRIAN J
IPC: B08B15/00
Filed: 2013-03-14
Abstract: A component extractor system includes a source of a positive pressure air stream and a source of a negative pressure air stream. Conduits convey the air streams to and from a work area where one or more nozzles create a capture region and draw airborne components into the system. The system is optimized in terms of flow ratios, dimensions of the conduits and elements of the nozzle, and so forth.
Patent EP-2844999-A1 (EP)
Inventor: MERCHANT HAMID ALI
IPC: G01N33/15
Filed: 2013-05-02
Abstract: Apparatus for testing the solubility of a medical dosage form includes a chamber (12) for holding a solvent medium (18), in the preferred embodiment a bicarbonate based buffer system. The apparatus also includes a pH probe (66) which is connectable to a supply of carbon dioxide (32, 34),as well as to a supply of helium (40), the supplies being controlled by a control unit (50). The control unit (50) monitors changes in pH of the solvent medium (18) and, as appropriate, feeds pH increasing and/or p H reducing gas from the supplies(32, 34, 40) into the chamber (12). The control unit (50) is able to maintain a uniform pH during testing or to provide a dynamically adjustable pH during testing, for example to three or more different pH levels in order to test the performance of a drug carrier at different levels of acidity or alkalinity for example, mimicking the conditions of the gastrointestinal tract. The apparatus(20) and associated method are particularly suitable for testing and developing dosage forms for oral delivery of drugs.
Patent EP-2853114-A1 (EP)
Inventor: DOUGLAS ROBERT KEITH
IPC: H04W28/10
Filed: 2013-05-22
Abstract: Apparatuses and methods that provide for implementing a body area network are disclosed. An example of a method described herein includes determining a plurality of paths from a source node to a destination node in a set of nodes; determining, for each path in the plurality of paths, a Path Figure of Merit (PFM); associating two or more paths in the plurality of paths with a connection based on a total PFM threshold for the connection; and communicating from the source node to the destination node using at least two of the paths associated with the connection. Apparatuses for implementing the methods are also disclosed herein.
Patent EP-2838575-A1 (EP)
Inventor: KRUCINSKA IZABELLA
IPC: A61L27/18
Filed: 2013-04-17
Abstract: The invention claimed concerns a medical material for reconstruction of blood vessels, the method of its production, as well as the application of that medical material reconstruction of blood vessels. More precisely, the invention concerns textile vascular prostheses for the reconstruction of small diameter blood vessels and solvent-free manufacturing method used to obtain the aforementioned small diameter vascular prostheses. The solution presented in this patent application concerns a new method of forming textile nanostructures to be applied in vascular surgery and cardiosurgery, especially in prosthetics of blood vessels below 6 mm in diameter, as well as a substrate for proliferation of vascular endothelium cells.
Patent EP-2872660-A1 (EP)
Title: Formteile aus korrosionsbeständigen kupferlegierungen
Inventor: AUFRECHT JOCHEN
IPC: C22F1/08
Filed: 2013-06-13
Abstract: Die Erfindung betrifft metallische Formteile, Verfahren zur Herstellung der Formteile, Verwendung der Formteile sowie die Verwendung von Legierungen zur Herstellung von Formteilen. Aus Kupfer-Legierungen der Zusammensetzung (in Gewichts-%) Sn: 2 bis 8 %, Zn: 2,5 bis 13 %, Pb: weniger als 0,25 %, Ni: maximal 0,6 %, wahlweise Phosphor, Rest Cu, jedoch mindestens 84 %, sowie unvermeidbaren Verunreinigungen werden Formteile hergestellt, wobei die Herstellung der Formteile mindestens einen Warmpressvorgang einschließt. Die so hergestellten Formteile weisen eine hervorragende Korrosionsbeständigkeit, sehr gute Materialeigenschaften, eine hohe Maßhaltigkeit sowie Oberflächenqualität auf und eignen sich daher speziell für die Verwendung in Wasser führenden Leitungssystemen.
Patent EP-2847647-A1 (EP)
Inventor: VENÅS ARNE W
IPC: G06F1/32
Filed: 2013-06-19
Abstract: Un microcontrôleur comprend au moins un processeur (8), un ou plusieurs systèmes périphériques (6) et un module d'alimentation en ressource (2). Le processeur (8) et le(s) système(s) périphérique(s) (6) sont chacun agencés de façon à générer un signal lorsqu'ils nécessitent de l'énergie et/ou un signal d'horloge. Ces signaux stimulent le module d'alimentation en ressource (2) afin que ce dernier fournisse la ressource exigée.
Patent EP-2870177-A1 (EP)
Inventor: BULLMAN JONATHAN
IPC: C07K16/22
Filed: 2013-07-03
Abstract: The invention relates to a method of treatment or prophylaxis of a neurological disorder, in particular but not exclusively amyotrophic lateral sclerosis (ALS), comprising administration of an anti-Nogo-A antibody.
Patent EP-2867481-A1 (EP)
Inventor: FONTANEL EDDY STÉPHANE JOËL
IPC: F01D25/18
Filed: 2013-06-12
Abstract: A pivot pin (7) designed to be rotated within a housing of a turbine engine, in particular for an aircraft, the pivot pin (7) comprising: - a circumferential main body (70) comprising a plurality of ventilation ports (71) designed to allow a plurality axial air flows (F) to flow upstream-to-downstream in the turbine engine, two consecutive ventilation ports (71) being linked by a connecting segment (72), and - a circumferential ring (8) for recovering a flow of lubricating oil (H) integral with the main body and radially inside said ventilation ports (71), the recovery ring (8) comprising a plurality of radial discharge ports (81) for allowing the discharge of a plurality of radial oil flows (H) to the outside, each discharge port (81) being radially aligned with a connecting segment (72) of the main body in such a way as to allow each flow of oil (H) to be discharged between the air flows (F).
Patent EP-2872450-A1 (EP)
Inventor: BARKER JEREMY
IPC: C01G53/00
Filed: 2013-07-10
Abstract: The invention relates to novel materials of the formula: A 1-δ  M 1 
 V  M 2 
 W  M 3 
 X  M 4 
 Y  M 5 
 Z  O 2  wherein A is one or more alkali metals comprising sodium and/or potassium either alone or in a mixture with lithium as a minor constituent; M 1  is nickel in oxidation state +2; M 2  comprises a metal in oxidation state +4selected from one or more of manganese, titanium and zirconium; M 3  comprises a metal in oxidation state +2, selected from one or more of magnesium, calcium, copper, zinc and cobalt; M 4  comprises a metal in oxidation state +4, selected from one or more of titanium, manganese and zirconium; M 5  comprises a metal in oxidation state +3, selected from one or more of aluminium, iron, cobalt, molybdenum, chromium, vanadium, scandium and yttrium; wherein 0 ≤δ≤0.1 V is in the range 0 < V <0.5; W is in the range 0 <W≤ 0.5; X is in the range 0 ≤ X < 0.5; Y is in the range 0 ≤ Y < 0.5; Z is ≥0; and further wherein V + W + X + Y + Z = 1. Such materials are useful, for example, as electrode materials in sodium ion battery applications.
Patent EP-3027383-A1 (EP)
Title: Verfahren zur herstellung eines mit einer verschleissschutzschicht versehenen doppelschneckenzylinders
Inventor: BENDIG PETER
IPC: B29C48/40
Filed: 2013-08-01
Abstract: Die Erfindung betrifft ein Verfahren zur Herstellung eines mit einer Verschleissschutzschicht versehenen Doppelschneckenzylinders (1), bei welchem zwei im wesentlichen parallel zueinander verlaufende und einander durchdringende Bohrungen (11, 12) in einen Zylinder eingebracht werden und anschliessend in die Bohrungen (11, 12) zwei mit im wesentlichen C-förmig ausgebildetem Querschnitt versehene und im Durchdringungsbereich (10) der Bohrungen (11, 12) einander fortsetzende Auskleidungen (21, 22) eingebracht werden, die die Innenoberfläche (110, 120) der Bohrungen (11, 12) bilden und als Verschleissschutzschicht dienen, dadurch gekennzeichnet, dass zunächst eine erste rohrförmige Auskleidung (21) in eine erste der Bohrungen (11) eingebracht wird und dann unter Ausbildung des C- förmigen Querschnittes gemäss dem Durchmesser (D) der anderen Boh- rung (12)aufgetrennt wird und anschliessend eine zweite rohrförmige Auskleidung (22) in die zweite der Bohrungen (12) eingebracht wird und dann unter Ausbildung des C-förmigen Querschnittes gemäss dem Durchmesser (A) der von der ersten Auskleidung (21) gebildeten Innen- Oberfläche (110) der ersten Bohrung (11) aufgetrennt wird.
Patent EP-2818480-A1 (EP)
Inventor: PARK SOON JAE
IPC: A61K47/48
Filed: 2013-02-22
Abstract: The present invention relates to an antibody in which a motif composed of an amino acid or peptide sequence including one or more cysteine residues is bound to the terminus of a parent antibody, particularly the terminus of the heavy chain of the parent antibody. Also, the present invention relates to a modified antibody-drug conjugate (mADC) comprising a drug bound to the antibody, and a method for producing the antibody or the modified antibody-drug conjugate. The modified antibody-drug conjugate according to the invention can accurately deliver the drug to a target cell due its high specificity to antigen, and thus can increase the therapeutic effect of the drug. Also, it can increase the usability of drugs, particularly anticancer drugs, the use of which is restricted due to their toxicity, despite their high efficacy. Moreover, the invention relates to a composition for treatment of diseases, particularly cancers, which comprise the modified antibody-drug conjugate.
Patent EP-2818367-A1 (EP)
Inventor: KOJIMA SHUNPEI
IPC: F16B5/12
Filed: 2013-02-21
Abstract: A bumper fixing clip includes a leg portion engaging with a vehicle body panel; engagement claws engaging with a plurality of engagement holes formed on a bumper side; and an engagement member including a second engagement claw engageable with or retractable from one of the engagement holes formed on the bumper side by operating an operation portion, and fixing the bumper to the vehicle body panel. The engagement member is integrally formed with a fixing clip main body, and includes an approximately rod-like operation portion; the second engagement claw formed in a vicinity of a turning center of the operation portion; and an abutment piece formed on a side opposite to the second engagement claw. Also, the fixing clip main body includes a control portion abutting against the abutment piece of the operation portion, and controlling a moving range of the operation portion so as to reduce a force operating the operation portion, and even if an excessive force is applied, the moving range is controlled so as to prevent a breakage.
Patent EP-2822600-A1 (EP)
Inventor: HARMON BRENDAN
IPC: A61K48/00
Filed: 2013-03-11
Abstract: Disclosed herein are methods and compositions for the treatment of diseases of the CNS with nucleic acid nanoparticles. Compositions are also disclosed herein that utilize nucleic acid nanoparticles to treat conditions such as Parkinson's Disease. Furthermore, methods of intranasally administering the compacted nucleic acid nanoparticles for therapeutic purposes in the brain are disclosed.
Patent EP-2834711-A1 (EP)
Inventor: NATORI JUNICHIRO
IPC: G03G15/00
Filed: 2013-03-28
Abstract: To provide an elastic member for image forming apparatus, which contains: a base; and an elastic layer provided on the base, wherein the elastic layer contains a polymer having a structure derived from terpene and a structure where a main chain contains a silicon atom.
Patent EP-2898684-A1 (EP)
Inventor: WANG YE-KUI
IPC: H04N19/00
Filed: 2013-09-23
Abstract: A video coding device, such as a video encoder or a video decoder, may be configured to code a sub-picture timing supplemental enhancement information (SEI) message associated with a first decoding unit (DU) of an access unit (AU). The video coding device may further code a duration between coded picture buffer (CPB) removal time of a second DU of the AU in decoding order and CPB removal time of the first DU in the sub-picture SEI message. The coding device may also derive a CPB removal time of the first DU based at least in part on the sub-picture timing SEI message.
Patent EP-2917046-A1 (EP)
Inventor: GARDARIN BENOÎT
IPC: B60C9/02
Filed: 2013-11-05
Abstract: Tyre comprising a carcass reinforcement (60) and having an outer profile (200) such that the distance between both, measured between a point of the carcass and the point of intersection between the outer profile and a direction perpendicular to the carcass passing through this point of the carcass, reaches its minimum value DMI at a first point (62) of the carcass having a radial height HD ≥ 0.50· Η and ≤ 0.75-H, H being the radial height of the tyre; the tyre comprising: a first zone (Z1) surrounding the first point (62), wherein the distance between the carcass and the outer profile increases continuously while moving away from the first point (62), radially inward and radially outward, up to a distance (DMA) at the radially inner end point of the first zone ≥ 1.3 DMI; a second zone (Z2) adjacent to and radially inside of the first zone (Z1), wherein the distance between the carcass and the outer profile is constant or decreases continuously while moving radially inwardly; and a third zone (Z3) adjacent to and radially inside of the second zone (Z2), wherein the distance between the carcass and the outer profile increases again.
Patent EP-2847890-A1 (EP)
Inventor: KOC ALI T
IPC: H04W36/30
Filed: 2013-05-11
Abstract: Systems and methods are disclosed for communicating enhanced user equipment (UE) assistance information between nodes in wireless communication systems. The UE achieves power savings and latency requirements more effectively by communicating its preferences, constraints and/or requirements to an evolved Node B (eNodeB) in the form of UE assistance information. The UE assistance information may include, for example, an indication of a preferred set of discontinuous reception (DRX) settings, current data traffic conditions, expected data traffic conditions, power or performance preferences, and/or an indication of the UE's mobility between cells.
Patent EP-3057643-A1 (EP)
Title: High pressure tear resistant balloon
Inventor: HORN DANIEL J
IPC: A61M25/10
Filed: 2013-10-24
Abstract: An expandable medical balloon comprising an inner layer (12) formed of a polymer material having a first flexural modulus, an intermediate layer (14) formed of a material having a second flexural and an outer layer (16) formed of a material having a third flexural modulus, wherein the flexural modulus of the inner layer and outer layer is 3,4 atm to about 5,44 atm, the flexural modulus of the intermediate layer is about 8,85 atm to about 15,7 atm and the calculated burst strength of the balloon determined on a 90 degree bend in the balloon is about 2,38 atm or higher.
Patent EP-2852007-A1 (EP)
Inventor: TANIGUCHI KEIICHI
IPC: H01R13/6471
Filed: 2013-05-14
Abstract: The invention provides a connector capable of reducing crosstalk between contacts. The connector includes first and second contacts 200a and 200b aligned at a first height along a first direction X in a body 100, a third contact 200c provided at a second height between the first and second contacts 200a and 200b in the body 100, and fourth contacts 300a disposed at a third height other than the first and second heights, on the sides in the first direction X of the third contact 200c in the body 100. The third contact 200c includes a third body 210c (crosstalk reduction portion), and the first and second contacts 200a and 200b respectively include first and second bodies 210a and 210b (first and second corresponding portions). The third body 210c is located closer to the fourth contacts 300a than the first and second bodies 210a and 210b are.
Patent EP-2872164-A1 (EP)
Title: Protéine 9 associée à c1q/tnf (ctrp9) et utilisation dans la prévention et le traitement de troubles métaboliques
Inventor: WONG GUANG WILLIAM
IPC: A61P3/00
Filed: 2013-05-28
Abstract: L'invention concerne des compositions et des méthodes pour le traitement de l'obésité et/ou du diabète de type II et des troubles métaboliques associés, les procédés et traitements comprenant une quantité efficace d'une protéine 9 associée à C1q/TNF (CTRP9) isolée et/ou purifiée ou une partie fonctionnelle de celle-ci, et un vecteur pharmaceutiquement acceptable. L'invention concerne des procédés de criblage pour des molécules qui élèvent les taux de CTRP9  in vivo . Les présents inventeurs fournissent la première preuve  in vivo  reliant CTRP9 à la régulation de métabolisme des graisses dans le foie et le muscle squelettique par l'intermédiaire de la voie de signalisation AMPK, et soulignent sa fonction métabolique protectrice dans le contexte lésions métaboliques à médiation par HFD.
Patent EP-2923049-A1 (EP)
Inventor: WOUTERS PAUL
IPC: F01N3/20
Filed: 2013-11-14
Abstract: The invention concerns a method for managing the operation of a component of a system for storing and injecting an additive into the exhaust gases of a combustion engine. Said system comprises a container for storing the additive and said method comprises the following steps: - obtaining an instantaneous measurement of the concentration of additive and/or an instantaneous measurement of the alkalinity of the additive and/or an instantaneous measurement of the temperature inside the container, by means of one or a plurality of measurement sensors mounted inside the container; - determining the reducing power of the additive on the basis of the instantaneous measurement of the concentration of additive and/or an instantaneous measurement of the alkalinity of the additive and/or an instantaneous measurement of the temperature inside the container; - generating a control signal, on the basis of the defined reducing power; - transmitting the generated control signal to the component.