baber/WOPTO huggingface dataset:
Patent WO-2019099644-A1 (WO)
Title: Méthodes et kits pour utiliser des micro-organismes recombinés en tant que réactifs directs dans des applications biologiques
Inventor: ELLINGTON ANDREW
IPC: C12N11/18
Filed: 2018-11-15
Abstract: L'invention concerne une méthode d'utilisation d'une enzyme dans un procédé de manipulation d'acide nucléique, la méthode comprenant : a) la transformation d'un micro-organisme avec une enzyme non native; b) l'induction de l'expression de l'enzyme dans le micro-organisme, ce qui permet de produire l'enzyme non native; c) l'ajout du micro-organisme de l'étape b) directement à un procédé de manipulation d'acide nucléique non naturel, l'enzyme non native n'étant pas purifiée à partir du micro-organisme avant l'ajout au procédé de manipulation d'acide nucléique; et la réalisation du procédé de manipulation d'acide nucléique à l'aide de l'enzyme. Il est important de noter que cette méthode peut être mise en œuvre sans qu'il soit nécessaire de purifier l'enzyme de la cellule la produisant avant qu'elle soit utilisée dans la méthode de manipulation d'acide nucléique. L'invention concerne également un kit permettant de mettre en oeuvre un procédé de manipulation d'acide nucléique, le kit comprenant a) un micro-organisme exprimant une enzyme non native; b) des acides nucléiques d'intérêt; et c) des réactifs destinés à être utilisés dans le procédé de manipulation d'acide nucléique.
Patent WO-2019108713-A1 (WO)
Inventor: ZERHUSEN JADEN
IPC: C11D3/22
Filed: 2018-11-29
Abstract: L'invention concerne une composition comprenant une pluralité de particules, les particules comprenant : d'environ 25 % à environ 94 % en poids d'un vecteur hydrosoluble ; d'environ 5 % à environ 45 % en poids d'un composé d'ammonium quaternaire ; et d'environ 0,5 % à environ 10 % en poids d'un polymère cationique ; chacune des particules présentant une masse d'environ 1 mg à environ 1 g ; et la composition ayant une viscosité d'environ 1 Pa.s à environ 10 Pa.s à 65 °C.
Patent WO-2020139319-A1 (WO)
Inventor: GALLEHER RYAN
IPC: G01C21/36
Filed: 2018-12-26
Abstract: L'invention concerne des systèmes et des procédés permettant de générer une application cartographique qui affiche une carte initiale présentant un niveau de zoom fondé sur un temps de déplacement associé à l'emplacement de l'utilisateur. L'application cartographique reçoit une demande de présentation d'une carte numérique en provenance d'un dispositif de client. En fonction de l'emplacement géographique en cours du dispositif de client, l'application cartographique estime une distance dans laquelle un utilisateur du dispositif de client peut se déplacer dans une période de temps particulière. L'application cartographique sélectionne ensuite un paramètre destiné à une fenêtre d'affichage de la carte numérique au moins en fonction de la distance estimée. Par exemple, le paramètre de fenêtre d'affichage peut être un niveau de zoom. L'application cartographique génère ensuite la carte numérique conformément au paramètre sélectionné, et affiche la carte numérique par l'intermédiaire d'une interface utilisateur du dispositif de client.
Patent WO-2019140398-A1 (WO)
Inventor: KARAFIN JONATHAN
IPC: G02B27/00
Filed: 2019-01-14
Abstract: L'invention concerne des techniques de codage optique holographique et diffractif pour former des hologrammes de réflexion ou de transmission. Le dispositif de codage comprend un substrat ayant un motif d'interférence qui peut propager la lumière le long d'un trajet de propagation de lumière d'un côté du substrat à un autre côté du substrat. En outre, un élément optique peut être utilisé pour propager la lumière selon un système de coordonnées de champ lumineux à quatre dimensions.
Patent WO-2019152742-A1 (WO)
Title: Chimeric antigen receptors targeting cd70
Inventor: SRIVATSA SRINIVASAN SURABHI
IPC: C07K16/28
Filed: 2019-01-31
Abstract: The disclosure provides CARs (CARs) that specifically bind to CD70. The disclosure further relates to engineered immune cells comprising such CARs, CAR-encoding nucleic acids, and methods of making such CARs, engineered immune cells, and nucleic acids. The disclosure further relates to therapeutic methods for use of these CARs and engineered immune cells comprising these CARs for the treatment of a condition associated with malignant cells expressing CD70 (e.g., cancer).
Patent WO-2019164871-A1 (WO)
Title: Tets recharged patient alert system for lvad patients
Inventor: CINBIS CAN
IPC: A61M1/10
Filed: 2019-02-20
Abstract: A medical implant information reporting device and method of charging the same, the reporting device having an integrated harvesting coil configured to couple energy from an electromagnetic field of a source coil to induce current in the harvesting coil, are provided. According to one aspect, a method includes electrically coupling the harvesting coil to the source coil to charge the medical implant information reporting device, the source coil being sized to be removably disposed one of on and around the torso of a patient and configured to inductively power a medical implant about which the medical implant information reporting device reports.
Patent WO-2019165313-A1 (WO)
Title: Plantar heel pain syndrome (plantar fasciitis) treatment
Inventor: RADOVIC PHILIP ANDREW
IPC: A61P21/02
Filed: 2019-02-22
Abstract: Plantar Heel Pain Syndrome can be of one or more etiologies and symptoms which refutes the mistaken tendency to categorize all plantar heel pain singularly as either plantar fasciitis or fasciosis. Recognizing that there is likely an interplay of inflammatory, degenerative and neuropathic etiologic conditions of this often-difficult malady to treat, a novel injection paradigm of botulinum toxin is explored in the treatment of 4 distinct presentations of Plantar Heel Pain Syndrome with promising results.
Patent WO-2019216974-A1 (WO)
Title: Random access response window ambiguity for multiple message1 transmissions
Inventor: ISLAM MUHAMMAD NAZMUL
IPC: H04W74/08
Filed: 2019-02-28
Abstract: Methods, systems, and devices for wireless communications are described. A user equipment (UE) may transmit two or more connection requests prior to expiration of a UE connection response window. In some examples, the UE may re-set a UE connection response window each time the UE transmits a connection request. In some examples, the base station and UE may set their respective connection response windows after the UE transmits connections requests in a set of consecutive transmission opportunities. In some examples, the base station and UE may set their respective connection response windows based at least in part on a first available transmission opportunity. In some examples, the UE may include an indication of a position in a transmission sequence in the connection response, and the base station may set the UE connection response window based at least in part on the indication.
Patent WO-2019191179-A1 (WO)
Title: Three-dimensional micro-electro-mechanical, microfluidic, and micro-optical systems
Inventor: NIELSON GREGORY NOLAN
IPC: H05K1/18
Filed: 2019-03-27
Abstract: Various three-dimensional devices that can be formed within the bulk of a semiconductor by photo-controlled selective etching are described herein. With more particularity, semiconductor devices that incorporate three-dimensional electrical vias, waveguides, or fluidic channels that are disposed within a semiconductor are described herein. In an exemplary embodiment, a three-dimensional interposer chip includes an electrical via, a waveguide, and a fluidic channel, wherein the via, the waveguide, and the fluidic channel are disposed within the body of a semiconductor element rather than being deposited on a surface. The three-dimensional interposer is usable to make electrical, optical, or fluidic connections between two or more devices.
Patent WO-2020171832-A1 (WO)
Title: Ustensile de cuisson et procédé de fabrication associé
Inventor: SEMENIC TADEJ
IPC: A47J27/024
Filed: 2019-03-27
Abstract: La présente invention concerne un ustensile de cuisson et un procédé de fabrication associé. Le procédé comprend la formation d'un conduit de fluide définissant un volume dans une base de l'ustensile de cuisson, la base comprenant une zone de chauffage configurée pour une communication thermique avec le conduit de fluide. Un fluide de travail est introduit dans le conduit de fluide par l'intermédiaire d'une extrémité ouverte du conduit de fluide. Une phase liquide du fluide de travail occupe un volume inférieur à celui du conduit de fluide. Le conduit de fluide est dimensionné et configuré pour former des segments de vapeur et des segments de liquide intercalés dans le conduit de fluide à partir du fluide de travail. L'extrémité ouverte du conduit de fluide est rendue étanche pour définir un système de fluide fermé.
Patent WO-2019195667-A1 (WO)
Title: Apparatus and methods for approximating and securing tissue
Inventor: FISCHELL RACHEL
IPC: A61B17/06
Filed: 2019-04-05
Abstract: Disclosed is a device that uses suture to close various layers of tissue quickly and precisely. The device and methods enhance the efficiency, consistency and cost-effectiveness of traditional hand-suturing without compromising cosmetic or wound healing outcomes. Adjustable instruments on either side of the device are applied to opposing sides of the desired layer of tissue to approximate the edges of the tissue to be closed. The user may control the delivery of a single stitch or a series of stitches at an adjustable interval to the desired layer of tissue. An instrument may perform the stitch or series of stitches as the operator guides the device along the tissue opening. Once the device has delivered the appropriate stitch(es), the user may remove excess suture material and release the tissue from the instruments on either side of the incision and the process may be repeated as necessary to close a wound.
Patent WO-2019200208-A1 (WO)
Title: Advanced passive wedge wire screen intake
Inventor: EKHOLM MICHAEL
IPC: B01D25/24
Filed: 2019-04-12
Abstract: Screen intake assemblies and related methods of fabrication and operation that improve both operational performance and structural strength. The screen intake assembly can include one or more screen portions that run substantially and continually along the length of the screen assembly to provide increase fluid intake and uniform flow. The screen intake assembly can comprise a central manifold having an exterior manifold screen portion to provide additional filtering capacity. The screen intake assembly can be used alone or in combination with internal flow modifier structures to increase fluid intake and uniformity. Internal flow modifiers can include a perforated flow modifier pipe, an internal flow modifier pipe, and/or converging flow modifiers. The screen intake assembly can include cleaning systems that operate continuously or on demand.
Patent WO-2019204290-A1 (WO)
Title: Wicks for candles and other lighting devices
Inventor: DECKER DAYNA
IPC: F23D3/08
Filed: 2019-04-16
Abstract: A wick includes a sheet of wick material. The wick has a height dimension, a width dimension, and a thickness dimension. The height dimension and the width dimension are greater than the thickness dimension. The height dimension extends from the top of the wick to the bottom of the wick as the wick is oriented when provided in a candle. The width dimension and the thickness dimension are perpendicular to the height dimension. The sheet of wick material may be dyed, provided with a visible pattern and/or provided with a plurality of cut-out portions.
Patent WO-2019204559-A1 (WO)
Title: Heart valve sealing devices and delivery devices therefor
Inventor: FRESCHAUF LAUREN
IPC: A61F2/24
Filed: 2019-04-18
Abstract: A valve repair device for repairing a native heart valve of a patient includes a pair of clasps, where each clasp is configured to attach to native valve leaflet. The ends of the pair of clasps can move away from one another to a partially open position when the native valve leaflets open during a diastolic phase of a cardiac cycle, and the ends of the pair of clasps can move toward one another when the native valve leaflets close during a systolic phase of a cardiac cycle.
Patent WO-2019217857-A1 (WO)
Title: Lidar system based on complementary modulation of multiple lasers and coherent receiver for simultaneous range and velocity measurement
Inventor: SANDBOM PHILLIP
IPC: G01S7/481
Filed: 2019-05-10
Abstract: A LIDAR system and method for determining a distance and a velocity of a target. The LIDAR system can include laser bank (62) is configured to generate a laser field from a first laser beam having a positive frequency sweep and a second laser beam having a negative frequency sweep, an optical combiner (65), an optical coupler (63), a photoreceiver (66), and a control circuit (69). The optical coupler direct a first portion of the laser field at the target such that the first portion is reflected by the target to the optical combiner. The optical combiner can optically combine the portions of the laser field. The output an l-output (67) and a Q-output (68) according to the optically combined portions of the laser field. The control circuit can determine a nominal beat frequency, which corresponds to the distance of the target, and a frequency shift, which corresponds to the velocity of the target, accordingly.
Patent WO-2019226975-A1 (WO)
Title: Combination therapies for treating cancer
Inventor: CASTILLA LUCIO
IPC: C07D401/04
Filed: 2019-05-24
Abstract: This invention relates to methods and compositions for treatment of inv (16) leukemia and particularly to treatment of acute myeloid leukemia. Disclosed is a method of treating inv (16) leukemia comprising the step of administering to a subject in need thereof a therapeutically effective combination of a) a compound of the formula (1) (1) and b) a BRD4 inhibitor selected from the group consisting of JQ1, CeMMECZ, l-BET 151 (or GSK1210151A), l-BET 762 (or GSK525762), PFI-1, bromosporine, OTX-015 (or MK-8628), TEN-010, CPI- 203, CPI-0610, RVX-208, BI2536, TG101348, LY294002, ABBV-075 (or mivebresib), FT-1101, ZEN003694, pharmaceutically acceptable salts and mixtures thereof. The therapeutically effective combination synergistically inhibits proliferation of inv (16) leukemia cells. This invention also relates to pharmaceutical compositions comprising a therapeutically effective combination of the compound of formula (1) and the BRD4 inhibitor and a pharmaceutically acceptable excipient.
Patent WO-2019227045-A1 (WO)
Title: Vacuum cleaner having reconfigurable weight distribution
Inventor: THORNE JASON B
IPC: A47L9/32
Filed: 2019-05-24
Abstract: A vacuum assembly having a hand vacuum configuration and a wand vacuum configuration may include a dust cup, a suction motor fluidly coupled to the dust cup, and a power source. The suction motor and the power source may be transitionable between a wand vacuum position and a hand vacuum position. When the suction motor and the power source are in the wand vacuum position, the dust cup, the suction motor, and the power source may be arranged serially. When the suction motor and the power source are in the hand vacuum position, the suction motor and the power source may be arranged in parallel with the dust cup.
Patent WO-2019245968-A1 (WO)
Title: Support de gestion de câbles extensible universel
Inventor: SEDOR THOMAS M
IPC: H04Q1/06
Filed: 2019-06-17
Abstract: L'invention concerne un support de gestion de câbles (20) qui achemine des câbles dans une armoire ou un râtelier. Le support de gestion de câbles (20) comprend un rail de montage interne (30) et un rail de montage externe (70). Le rail de montage externe (70) est fixé au rail de montage interne (30) par des éléments de fixation (90). Le rail de montage interne (30) comporte une bride supérieure (40), des première et seconde brides d'extrémité (32, 34), une bride inférieure (46) et une surface latérale (52). Le rail de montage externe (70) possède une bride supérieure (76), une bride d'extrémité (72), une bride inférieure (80) et une surface latérale (84). Les surfaces latérales (52, 84) du rail de montage interne (30) et du rail de montage externe (70) présentent une pluralité d'éléments de montage (54, 88) permettant de fixer des agrafes de groupage qui reçoivent une pluralité de câbles.
Patent WO-2019246266-A1 (WO)
Title: Accessoire de poignée endoscopique à utiliser avec un dispositif de fermeture par suture
Inventor: DEUEL CHRISTOPHER R
IPC: A61B1/00
Filed: 2019-06-19
Abstract: L'invention concerne un accessoire de poignée endoscopique, conçu pour être fixé à un endoscope comprenant un canal de travail et utilisé en combinaison avec un dispositif de suture conçu pour s'étendre à travers le canal de travail. L'accessoire comprend un armature conçue pour se conformer à une surface extérieure de l'endoscope et qui comporte au moins un élément d'accessoire conçu pour permettre une fixation amovible sur l'endoscope. Un bras principal s'étend radialement vers l'extérieur à partir de l'armature et comprend au moins un point de fixation, cet au moins un point de fixation étant conçu pour fixer de manière amovible une poignée proximale du dispositif de suture, de telle sorte qu'une poignée de translation peut être déplacée par rapport à la poignée proximale sans qu'un opérateur ait besoin de maintenir séparément la poignée proximale.
Patent WO-2020005746-A1 (WO)
Title: Two-step authentication using push to talk
Inventor: TAN WOEI CHYUAN
IPC: H04W4/10
Filed: 2019-06-21
Abstract: A method and apparatus for providing two-step authentication is provided herein. During operation, the two parts of authentication comprise (1) something a user knows, for example, a password; and (2) a push-to-talk (PTT) communication over a predetermined talkgroup.
Patent WO-2020014193-A1 (WO)
Inventor: MOREJOHN DWIGHT
IPC: A61B17/02
Filed: 2019-07-09
Abstract: L'invention concerne des dispositifs et des instruments médicaux, en particulier des systèmes et des dispositifs d'accès péricardique et des procédés associés. Certains exemples de dispositifs d'accès péricardique peuvent comprendre une jupe extensible placée de manière distale, configurée pour venir en prise avec le péricarde. Lorsqu'elle est déployée, la jupe peut être plus large que le corps tubulaire du dispositif. Certains exemples de dispositifs d'accès péricardique peuvent comprendre une pointe repositionnable au moins partiellement transparente.
Patent WO-2020018780-A1 (WO)
Title: Passively adjustable elements for earth-boring tools and related tools and methods
Inventor: ETEBU EBITMITULA
IPC: E21B10/32
Filed: 2019-07-18
Abstract: Passively adjustable elements for earth-boring tools may include a housing and an element located at least partially within the housing. A piston may be secured to the element, the piston configured to drive extension and retraction of the element relative to the housing. A first flow path may extend through the piston, through a first flow controller supported by the piston to permit fluid to flow at a first rate during retraction of the element. A second flow path may extend at least partially through the piston, through a second flow controller supported by the piston, to permit fluid to flow at a second, faster rate during extension of the element. A biasing element may bias the piston toward an extended position. An outer diameter of the piston may be less than or at least substantially equal to an outer diameter of the element.
Patent WO-2020037110-A1 (WO)
Title: Network-assisted sidelink scheduling techniques
Inventor: WU ZHIBIN
IPC: H04W72/04
Filed: 2019-08-15
Abstract: Aspects directed towards a network-assisted sidelink scheduling operation are disclosed. In one example, a scheduled entity receives a grant of resources from a scheduling entity operating according to a legacy radio access technology (RAT), and translates the grant of resources from a legacy configuration of resources to a non-legacy configuration of resources. The scheduled entity then performs a sidelink communication via the non-legacy configuration of resources. In another example, a scheduling entity operating according to a legacy RAT transmits a system information block (SIB) to a scheduled entity indicating that the scheduling entity can allocate non-legacy resources. The scheduling entity then receives a request for resources from the scheduled entity that corresponds to a non-legacy sidelink communication, and provides a grant of resources to the scheduled entity that includes a non-legacy-specific frequency for transmitting the non-legacy sidelink communication.
Patent WO-2020047507-A1 (WO)
Inventor: MARTIN GEOFFREY
IPC: B62D55/265
Filed: 2019-08-30
Abstract: A remotely-controlled, movable, magnetic system and method for surveillance and attack prevention. The system includes a motive apparatus including a mounting body for mounting a series of magnets and wheels or rollers and suspending the apparatus from a magnetic ceiling T-bar grid or alternative metal track. The wheels or rollers make contact with the T-bars or track; provide some space between the magnets and T-bars or track; and allow for movement of the system along the T-bar grid or track. One or more of the wheels is drivingly connected to a drive motor. The system further includes a processor, an input/output interface, and a remote computing device or remote control for controlling the motive apparatus via a communications network. The motive apparatus further mounts components and tools remotely controlled by a user for observing, identifying a potential attacker, and hindering a potential attack.
Patent WO-2020051105-A1 (WO)
Title: Dimethyl amino azetidine amides as jak inhibitors
Inventor: LONG DANIEL D
IPC: C07D471/04
Filed: 2019-09-03
Abstract: The invention provides compounds of formula (I): where the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are useful as JAK kinase inhibitors. The invention also provides pharmaceutical compositions comprising such compounds and methods of using such compounds to treat respiratory diseases.
Patent WO-2020051293-A1 (WO)
Title: Recurrence gene signature across multiple cancer types
Inventor: HU HAI
IPC: C12Q1/6883
Filed: 2019-09-05
Abstract: The present disclosure provides gene expression profiles that are associated with cancer, including certain gene expression profiles that differentiate between cancer that is at a high risk of recurrence. The gene expression profiles can be measured at the nucleic acid or protein level. The gene expression profiles can also be used to identify a subject for cancer treatment. Also provided are kits for use in predicting cancer recurrence and/or prognosing cancer and an array comprising probes for detecting the unique gene expression profiles associated with cancer.
Patent WO-2020056380-A1 (WO)
Title: Locating and attaching interchangeable tools in-situ
Inventor: TAYOUN ANTHONY
IPC: B25J11/00
Filed: 2019-09-13
Abstract: Current technologies allow a robot to acquire a tool only if the tool is in a set known location, such as in a rack. In an embodiment, a method and corresponding system, can determine the previously unknown pose of a tool freely placed in an environment. The method can then calculate a trajectory that allows for a robot to move from its current position to the tool and attach with the tool. In such a way, tools can be located and used by a robot when placed at any location in an environment.
Patent WO-2020068809-A1 (WO)
Title: Systems and methods for identifying individual doses of medication
Inventor: BANKS WILLARD DEAN
IPC: G16H20/10
Filed: 2019-09-24
Abstract: A system for uniquely identifying a medication unit such as a pill, a tablet, or a capsule includes a unique identifier located directly on the medication unit that distinguishes the medication unit from any medication unit. The system further includes a database that is hosted on a server device, the database being searchable to identify the medication unit and including the unique identifier and other information associated with the medication unit. The system further includes a scanner that scans the unique identifier to provide the unique identifier to a user device that communicates with the server device via a network to identify the medication unit.