baber/WOPTO huggingface dataset:
Patent RS-52012-B (RS)
Title: Bilayer pharmaceutical tablet comprising telmisartan and a diuretic and preparation thereof
Inventor: FRIEDL THOMAS
IPC: A61K31/4965
Filed: 2002-01-16
Abstract: A bilayer pharmaceutical tablet for the treatment of hypertension compring a first layer formulated for immediate release of the angiotensin II receptor antagonist telmisartan from a dissolving tablet matrix which contains telmisartan in substantially amorphous form, and a second layer formulated for immediate release of a thiazide diuretic from a fast disintegrating tablet matrix.
Patent RS-50880-B (RS)
Title: Crystalline form of omeprazole
Inventor: HAFNER MILAC
IPC: A61P1/04
Filed: 2002-04-24
Abstract: A novel crystalline form of the substrate known under the chemical name 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfiny]-1H-benzimidazole, and having the generic name omeprazole, hereinafter referred to as omeprozole form C, is disclosed. Further, a process for the preparation of omeprazole form C, a pharmaceutical formulation containing omeprazole form C in admixture with pharmaceutically acceptable excipients and the use of omeprazole form C for treatment of gastrointestinal disorders are disclosed.
Patent ZA-814027-B (ZA)
Title: Solventless uv cured thermosetting cement coat
Inventor: SATTLER FRANK ANTON
IPC: C08F2/50
Filed: 1981-06-15
Abstract: Disclosed is a solvent-free wire enamel cement coat which is curable to the B-stage with ultraviolet light. The wire can then be formed into a coil and cured with heat to the C-stage. The cement coat composition comprises a mixture of a UV photosensitizer and a curing agent with either an acrylated epoxy or an amine terminated acrylated epoxy or an acrylated urethane, or mixtures thereof, all dissolved in a monoacrylate. The composition can also include an end-blocked urethane, an acrylated hexamethoxymethyl melamine, or a low molecular weight cresol formaldehyde resin.
Patent ZA-817211-B (ZA)
Title: Process for preparing liquophilic polyamide membrane filter media and product
Inventor: PALL DAVID B
IPC: B01D65/10
Filed: 1981-10-19
Abstract: A process is provided for preparing skinless liquophilic alcohol-insoluble polyamide membranes by preparing at a first temperature a solution in a polyamide solvent having a temperature coefficient of solubility within the range from about 0.01 to about 5 weight per cent per degree Centrigrade of on alcohol-insoluble polyamide resin having a ratio CH2:NHCO of methylene CH2 to amide NHCO groups within the range from about 7:1 to about 12:1; inducing nucleation of the solution by controlled addition to the solution of a nonsolvent for the polyamide resin, under controlled conditions of concentration, temperature, addition rate, and degree of agitation to obtain a visible precipitate of polyamide resin particles which may or may not thereafter partially or completely redissolve, thereby forming a casting solution; spreading the casting solution on a substrate to form a thin film thereof on the substrate; cooling the film of casting solution to a second temperature sufficiently lower than the first temperature to precipitate polyamide resin from the casting solution; contacting and diluting the film of casting solution with a nonsolvent liquid, preferably containing a substantial proportion of the solvent liquid but less than the proportion in the casting solution, to precipitate polyamide resin from the casting solution in the form of a thin skinless liquophilic membrane; and washing and drying the resulting membrane; the alcohol-insoluble polyamide membranes obtained by this process have the unusual property of being liquophilic, i.e., readily wetted by organic liquids having a surface tension below about 60 dynes/cm, while being substantially not wetted by water, have absolute particle removal capabilities of the order of 0.1 to 5  mu M or more, and are useful as filter media for liquid systems in which such organic liquids are the continuous phase, as well as for separating immiscible liquid mixtures containing such liquids and liquids having a higher surface tension such as water.
Patent ZA-829103-B (ZA)
Title: Film dressing
Inventor: ROBERT WYLIE MCCRACKEN
IPC: A61L15/58
Filed: 1982-12-10
Abstract: A high moisture vapor permeable film dressing with an adhesive backing and a release sheet are disclosed. The dressing has two opposed side edges which are free of adhesive and a perforation through the adhesive near the side edge to allow the dressing to be applied to the patient and the adhesive-free edges removed, which prevents the edges of the dressing from rolling off the patient and dislodging the dressing.
Patent ZA-833883-B (ZA)
Title: Carbacyclin esters,process for their manufacture and their use as medicaments
Inventor: SKUBALLA WERNER
IPC: C07C69/708
Filed: 1983-05-27
Abstract: Carbacyclin esters of Formula I <CHEM>  wherein  R1 is an unsubstituted or substituted aromatic residue,  R2 is a free or functionally modified hydroxy group, R3 is an alkyl or cycloalkyl group, or an optionally substituted aryl group, or a heterocyclic group,  X is oxygen atom or the group -CH2-,  A is a -CH2-CH2-, trans-CH=CH-, or -C IDENTICAL C-group, W is a free or functionally modified hydroxy-methylene group or a free or functionally modified <CHEM>  wherein the OH-group can be in the  alpha - or  beta -position,  D is the group <CHEM> a straight-chain saturated alkylene group of 1-5 carbon atoms, a branched, saturated or a straight-chain or branched, unsaturated alkylene group of 2-5 carbon atoms, which groups can optionally be substituted by fluorine atoms, E is a direct bond, a -C IDENTICAL C- group, or a -CR4=CR5- group wherein R2 and R5 mean a hydrogen atom or an alkyl group of 1-5 carbon atoms; are useful as blood-pressure-lowering agents, inter alia.
Patent ZA-839231-B (ZA)
Title: Molecular cloning and characterization of a further gene sequence coding for human relaxin
Inventor: HUDSON PETER JOHN
IPC: C12N15/00
Filed: 1983-12-12
Abstract: Human H2-relaxin analogues are disclosed with modifications in the A and/or B peptide chains, as well as processes of preparing human H2-relaxin and analogues thereof.
Patent ZA-852919-B (ZA)
Title: Grf analogs iv
Inventor: VALE WYLIE WALKER JR
IPC: G01N33/68
Filed: 1985-04-18
Abstract: Human GRF(hGRF), rat GRF(rGRF), porcine GRF(pGRF) and bovine GRF(bGRF) have been earlier characterized and synthetized. The invention provides synthetic peptides which are extremely potent in stimulating the release of pituitary GH in animals, including humans, which have resistance to enzymatic degradation in the body, and which have the sequence: R1-R2-R3-Ala-Ile-Phe-Thr-R8-Ser-R10-Arg-R12-R13-R14-R15-Gln-R17-R18-Al a-Arg-Lys-Le u-R23-R24-R25-Ile-R27-R28-R29-Gln-Gln-Gly-Glu-R34-Asn-Gln-Glu-R38-R39- R40-Arg-R42- R43-R44 wherein R1 is Tyr, D-Tyr, Met, Phe, D-Phe, pCl-Phe, Lou, His or D-His having either a C< alpha >Me or N< alpha >Me substitution or being unsubstituted; R2 is Ala, D-Ala or D-NMA; R3 is Asp or D-Asp; R8 is Ser, Asn, D-Ser or D-Asn; R10 is Tyr or D-Tyr; R12 is Arg or Lys; R13 is Ile or Val; R14 is Leu or D-Leu; R15 is Gly or D-Ala; R17 is Leu or D-Leu; R18 is Tyr or Ser; R23 is Leu or D-Leu; R24 is His or Gln; R25 is Glu, Asp, D-Glu or D-Asp; R27 is Met, D-Met, Ala, Nle, Ile, Leu, Nva or Val; R28 is Asn or Ser; R29 is Arg or D-Arg; R34 is Arg or Ser; R34 is Gln or Arg; R39 is Arg or Gly; R40 is Ser or Ala; R42 is Phe, Ala or Val; R43 is Asn or Arg; R44 is a natural amino acid; provided however that any or all of the residues between R28 and R44, inclusive, may be deleted and provided also that R2 is D-NMA and/or R14 is D-Leu and/or R29 in is D-Arg. Those peptides as well as their nontoxic salts may also be used diagnostically.
Patent ZA-869156-B (ZA)
Title: Phenylacetaldehydes substituted by basic groups,their preparation and drugs containing these compounds
Inventor: SEITZ WERNER
IPC: A61P1/04
Filed: 1986-12-04
Abstract: Phenylacetaldehydes which are substituted by basic groups, of the formula   <IMAGE>   where R1 to R8, m and n have the meanings stated in the description, and their preparation are described. The substances are useful for the treatment of disorders.
Patent ZA-877084-B (ZA)
Title: Method of promoting wound-healing
Inventor: OOMS LEO ALFONS ANDRE
IPC: A61K45/00
Filed: 1987-09-21
Abstract: The use for the manufacture of a medicament for treating wounds of a compound having serotonin antagonistic properties. Wound-healing compositions containing a serotonin-antagonist as active ingredient and a process for preparing said wound-healing compositions.
Patent ZA-894210-B (ZA)
Title: Propanolamine derivatives
Inventor: KIENZLE FRANK
IPC: A61P3/00
Filed: 1989-06-02
Abstract: The propanolamine derivatives of the formula 
<IMAGE>
 in which R<1>, R<2>, R<3> and R<4> have the meanings indicated in the description, and the physiologically tolerated salts thereof have catabolic action and can be used for treating obesity, diabetes and conditions associated with increased protein breakdown, or as feed additive for fattening livestock. 
<??>They can be prepared by reduction of appropriate monoester monoamides of malonic acid or corresponding propanolamides.
Patent ZA-898725-B (ZA)
Title: Pesticides
Inventor: BLADE ROBERT JOHN
IPC: C07C231/12
Filed: 1989-11-15
Abstract: 1) The present Application discloses pesticidally active compounds of the formula (I):  Q Q<1> CR<2> = CR<3> CR<4> = CR<5>C (=X) NHR<1> or a salt thereof, wherein Q is an monocyclic aromatic ring, or fused bicyclic ring system of which at least one ring is aromatic containing 9 or 10 atoms of which one may be nitrogen and the rest carbon each optionally substituted, or Q is a dihalovinyl group or a group R<6>-C IDENTICAL C- where R<6> is C1-4 alkyl, tri C1-4 alkylsilyl, halogen or hydrogen; Q<1> is a 1,2-cyclopropyl ring optionally substituted by one or more groups selected from C1-3 alkyl, halo, C1-3 haloalkyl, alkynyl, or cyano; R<2>,R<3>, R<4> and R<5> are the same or different with at least one being hydrogen and the others being independently selected from hydrogen, halo, C1-4 alkyl or C1-4 haloalkyl; X is oxygen or sulphur; and R<1> is selected from hydrogen and C1-8 hydrocarbyl optionally substituted by dioxalanyl, halo, cyano, trifuoromethyl, trifluoromethylthio or C1-6 alkoxy, their preparation, pesticidal compositions containing them and their use against pests.
Patent ZA-919317-B (ZA)
Title: Novel hydroxamic acid and N-hydroxyurea derivatives and their use.
Inventor: IKEDA TAKAFUMI
IPC: A61K31/16
Filed: 1991-11-26
Abstract: Certain novel hydroxamic acid derivatives having the structureinhibit the enzyme lipoxygenase. These compounds, and the pharmaceutically acceptable salts thereof, are useful in the treatment or alleviation of inflammatory diseases, allergic conditions and cardiovascular diseases in mammals and as the active ingredient in pharmaceutical compositions for treating such conditions.
Patent ZA-924600-B (ZA)
Title: High production laser welding assembly and method
Inventor: NEIHEISEL GARY LOUIS
IPC: B23K26/10
Filed: 1992-06-23
Abstract: A method for butt welding metallic sheets along a relatively long common seam line by providing a plurality of laser welding devices aligned above the common seam line, and effectively spaced from one another along a longitudinal axis. In a preferred embodiment, each welding device is independently adjustable in a direction parallel to a transverse axis which is perpendicular to the longitudinal axis. The metallic sheets are aligned on the upper surface in abutting relationship along the seam line and clamped for welding. Each laser welds only a portion of the sheets along the seam line, and the length of the relative movement between the welding devices and the sheets is greater than the effective spacing distance between welding devices to insure that a continuous weld bead is provided along the common seam line. <IMAGE>
Patent ZA-927279-B (ZA)
Title: Imidazolylmethyl-pyridines
Inventor: GIGER RUDOLF KARL ANDREAS
IPC: A61K31/44
Filed: 1992-09-23
Abstract: Compounds of the formula I <IMAGE>  in which   R1 denotes alkyl having 1 to 4 carbon atoms, halogen having an atomic number of 9 to 35 or amino which is optionally mono- or disubstituted by alkyl having 1 to 4 carbon atoms, R2 and R3 independently of one another stand for hydrogen or alkyl having 1 to 4 carbon atoms and R4 denotes hydrogen, hydroxyl, alkyl or alkoxy each having 1 to 4 carbon atoms or halogen having an atomic number of 9 to 35, in the form of the free base or in acid addition salt form, can be used for the treatment of senile dementia and Alzheimer's disease and as antidepressant.
Patent ZA-929832-B (ZA)
Title: Bleach dispersion of long shelf life.
Inventor: ECKHARDT CLAUDE
IPC: D06L3/02
Filed: 1992-12-18
Abstract: A storage-stable bleach dispersion which, besides at least one peracid or the salts thereof, contains one or more optical brighteners of the bis-benzofuranyl type, and the production and use of this dispersion for the simultaneous bleaching and brightening, domestically or industrially, of fabrics at temperatures of +10 DEG C or above are described.
Patent ZA-931265-B (ZA)
Title: Device for the in situ repair of pipes, and method of repairing pipes.
Inventor: FREY ANDRE FRANWOIS
IPC: F16L55/1645
Filed: 1993-02-23
Abstract: The subject of the present invention is a device for the repair on-site of inaccessible conduits or ducts and a method for restoring using the same. Repairing device characterised in that it essentially consists of a set of at least four inflatable cylindrical elements (1, 2, 3, 4) of short length, joined together by spacers (5) articulated (5) by means of universal joints and joined by means for supplying inflation fluid and clogging product (7') under pressure, as well as by traction and/or retraction means, respectively to injection and actuation devices arranged at the surface and provided with corresponding control devices, the said set of elements (1, 2, 3, 4) making it possible to define a permanent chamber (10) for the injection of clogging product (7') under pressure into the conduit or the duct (11), allowing their continuous and complete repair as the said assembly progresses, and this also, if necessary, being at the level of misalignments (12), internal projections (13), openings of secondary ducts (14) or elbows (12'), whilst keeping the injection chamber (10) full of clogging product (7'). <IMAGE>
Patent ZA-937300-B (ZA)
Title: Multimeric polyvalent antithrombotic agents.
Inventor: DEAN RICHARD T
IPC: A61P7/02
Filed: 1993-10-01
Abstract: This invention relates to antithrombotic agents and uses thereof. Specifically, the invention relates to chemical moieties that specifically bind to platelets and inhibit their aggregation, including linear and cyclic peptides. The invention provides methods for using these antithrombotic agents to prevent the formation of thrombi at sites in a mammalian body. In particular, the platelet-specific binding moieties including linear and cyclic peptides of the invention are covalently linked to a polyvalent linker moiety, so that the polyvalent linker moiety is covalently linked to a multiplicity of the platelet-specific binding moieties including linear and cyclic peptides. Effficacious antithrombotic agents are thereby provided.
Patent ZA-953538-B (ZA)
Title: Method and appartus for molding opthalmic lenses using vacuum injection
Inventor: SU KAI CHIANG
IPC: B29C39/42
Filed: 1995-05-03
Abstract: A lens mold cavity is formed and then evacuated via a vacuum channel (3) contained within a mold member. A fluid valve (9) is opened to exposed the lens mold cavity to liquid lens material, whereby a vacuum of the lens mold cavity draws the liquid lens material to fill the lens mold cavity. The fluid valve is then closed and the liquid lens material within the lens mold cavity is cured to obtain an opthalmic lens such as a contact lens. <IMAGE>
Patent ZA-964638-B (ZA)
Title: Impact-resistant protective garment
Inventor: HONKALA MARKKU
IPC: A41D31/00
Filed: 1996-06-05
Abstract: PCT No. PCT/FI96/00336 Sec. 371 Date Feb. 5, 1997 Sec. 102(e) Date Feb. 5, 1997 PCT Filed Jun. 6, 1996 PCT Pub. No. WO96/39881 PCT Pub. Date Dec. 19, 1996An impact-resistant garment comprises closed rings (2) joined together to form a layer (1) protecting against impacts inside the garment. Elongate filling elements (3) of limited flexibility are threaded through the rings (2) to prevent the penetration of spike-shaped objects through the rings (2).
Patent ZA-972105-B (ZA)
Title: Top gripping carrier for bottles.
Inventor: AUCLAIR JEAN-MICHEL
IPC: B65D71/48
Filed: 1997-03-11
Abstract: An article carrier of the top gripping type includes a main panel (20, 116) having a pair of opposed end edges (70, 72, 170, 172), a first fold line (32, 134) extending between said end edges (70, 72, 170, 172), and at least one aperture (44, 144) for receiving an article (A). The aperture (44, 144) is disposed astride the first fold line (32, 134) to interrupt it. A first tab (40, 140) is struck from the main panel (20, 116) and defining at least a part of the aperture (44, 144). The tab (40, 140) is hingeably connected to the main panel (20, 116) so that the tab (40, 140) is displaceable out of the plane of the main panel (20, 116) to operatively engage a part of the article (A) when the article (A) is in the aperture (44, 144). The tab (40, 140) is connected to the main panel (20, 116) by means of a pair of second and third spaced fold lines (60, 62, 160, 162) extending divergently from each other toward one of the end edges (70, 72, 170, 172) so that displacement of the tab (40, 140) out of the plane of the main panel (20, 116) causes the main panel to be folded about the first fold line (32, 134). A stress relieving cut line (64, 164) is provided to extend between the second and third fold lines (60, 62 160, 162) to partially separate the tab (40, 140) from the main panel (20, 116). The cut (64, 164) line is disposed transversely of the first fold line (32, 134) such that the first fold line (32, 134) is interrupted at the cut line (64, 164). <IMAGE>
Patent ZA-975595-B (ZA)
Title: Rom-based finite impulse response filter for use in mobile telephone
Inventor: EASTON KENNETH D
IPC: H03H17/06
Filed: 1997-06-24
Abstract: The finite impulse response (FIR) filter is implemented as a table using read-only memory (ROM). The FIR filter table stores a pre-calculated output filter value for each permissible combination of input values to be filtered. Streams of input values are successively shifted into the table and corresponding output values are successively output. In an exemplary implementation, the FIR filter is employed within a digital cellular telephone for use in smoothing a digital signal to be transmitted. The size of the required FIR filter table is minimized by exploiting constraints imposed upon the signal to be filtered and by exploiting linearity and symmetry within the filter itself. More specifically, the telephone employs a data burst randomizer to provide a data signal composed of sequences of null or 0 values and sequences of antipodal values (+1's and -1's). Hence, the permissible input combinations for the FIR filter include only patterns containing either all antipodal signals, all null signals, leading antipodal signals followed by trailing null signals, or leading null signals followed by trailing antipodal signals. The FIR filter look up is configured to exploit these limitations on the input streams yielding a look up table having relatively few entries. Method and apparatus implementations are disclosed.
Patent ZA-981682-B (ZA)
Title: Method for training gun operating teams system forconducting the method and use of the system
Inventor: VUICHARD ALBIN
IPC: F41G3/26
Filed: 1998-02-27
Abstract: The method involves, before the operation of the fire release device, selectively at least one of the cannons is inactivated, in order to prevent the despatch of projectiles (16) when the fire release device is operated. The target is an aircraft (10), the timewise flight path of which is determined. The timewise flight path of the projectile from the non-inactivated cannon (12) is determined. The flight paths of the flying target and the projectile fired from the non-inactivated cannon are compared and from the comparison the defined minimal distance between the flying target and a fictitious projectile is defined as a firing error of the non-inactivated cannon. The fictitious flight path of a fictitious projectile is determined from the aiming position of the inactivated cannon at the moment of operation of the firing release device.
Patent ZA-985290-B (ZA)
Title: Process for the manufacture of carboxylic acids
Inventor: LANGE JEAN-PAUL
IPC: C07C51/14
Filed: 1998-06-18
Abstract: A process for manufacture of branched carboxylic acids from branched olefins by means of reaction with carbon monoxide and a solid acid catalyst, characterized in that a branched olefin, or a precursor thereof, is reacted in a batch reactor or a plug flow reactor with carbon monoxide and water, in the presence of an acidic ion exchanger, having sufficient acid groups to provide requisite protons for conversion of said olefin or a precursor of it, and carbon monoxide into branched carboxylic acids, and in the presence of a polar non-coordinating organic solvent.
Patent AT-408184-B (AT)
IPC: A61H35/00
Filed: 2000-02-21
Granted: 2001-09-25
Abstract: A massage unit for massaging the feet in water consists of a frame for nozzles 9, 10 directed on the one hand towards the sole and on the other hand towards the instep, and of a housing 3 which is connected to the frame, is protected from spray water and houses an electrically drivable pump 4 whose pressure attachment 6 can be connected to the nozzles 9, 10 and whose suction line 5 passes through the housing 3. To create advantageous structural features, it is proposed that the housing 3 for the pump 4 is attached to a water container 1 which forms the frame for the nozzles 9, 10 and which is closed, except for an admission opening 2, and in which the suction line 5 of the pump 4 opens out at the bottom, and the nozzles 9, 10 towards the sole and the instep are connected via separate pressure lines 12, 13 to the pressure attachment 6 of the pump 4, from which the pressure lines 12, 13 branching off in each case lead to the nozzles 9, 10 via a control valve 14, 15 provided outside the housing 3 for the pump 4. <IMAGE>
Patent GB-2411312-B (GB)
Title: Method and system for message content delivery
Inventor: CHARTERS GRAHAM CASTREE
IPC: H04L12/58
Filed: 2004-02-19
Granted: 2006-09-20
Abstract: A method and system are provided for delivery of messages. A publishing application publishes a message via a communication infrastructure and one or more subscriber applications receive the message from the communication infrastructure. A message content schema is provided which enables the content parts of a message type to be identified. The communication infrastructure enables the one or more subscriber applications to register interest in selected content parts of the message type and the communication infrastructure obtains a message instance of the message type populated with data of a combined content subset as registered by the one or more subscriber applications. The communication infrastructure then delivers the message instance to a subscriber application including the selected content parts by the subscriber application.
Patent GB-2410106-B (GB)
Title: Dynamic storage device pooling in a computer system
Inventor: MENO RANDY DE
IPC: G06F12/16
Filed: 2003-09-09
Granted: 2006-09-13
Abstract: A method for dynamically allocating control of a storage device, the method comprising receiving an access request from a first computer requesting access to a storage device; directing, based upon the access request, a first storage controller computer to assume an inactive state with respect to control of the storage device; and directing, based upon the access request, a second storage controller computer to assume an active state with respect to control of the storage device.