baber/WOPTO huggingface dataset:
Patent HU-T66429-A (HU)
Title: Compositions for treating osteoporosis
Inventor: MCOSKER JOCELYN ELAINE
IPC: A61P3/02
Filed: 1992-01-31
Abstract: Methods of treatment for osteoporosis in a human or other animal subject, comprising: administering a bone-active phosphonate to said subject, at a level of at least about 0.1 LED per day of said treatment; and administering an estrogen hormone to said subject at a level of from about 0.2 to about 0.8 LED per day of said treatment. The bone-active phosphonate is preferably a bisphosphonate, or a phosphonoalkyl phosphonate.
Patent HU-T71110-A (HU)
Title: 4-aryloxy- and 4-arylthiopiperidine derivatives, pharmaceutical compositions containing them and process for their preparation
Inventor: GOTTSCHLICH RUDOLF
IPC: A61P9/12
Filed: 1994-07-21
Abstract: Novel 4-aryloxy- or 4-arylthiopiperidine derivatives of the formula I   <IMAGE>  in which   R<1> and R<2> in each case independently of one another are phenyl radicals which are unsubstituted or substituted one or two times by A, OH, OA, aryloxy having 6-10 C atoms, aralkyloxy having 7-11 C atoms, -O-(CH2)n-O-, Hal, CF3, NO2, NH2, NHA, NA2, NHAc, NAAc, NHSO2A and/or NASO2A,   X is O, S, SO or SO2,   m is 1, 2 or 3,   n is 1 or 2,   A is an alkyl radical having 1-6 C atoms,   Hal is F, Cl, Br or I  and Ac is alkanoyl having 1-8 C atoms, aralkanoyl having 1-10 C atoms or aroyl having 7-11 C atoms, and their physiologically acceptable salts, have an action affecting the central nervous system, in particular neuroleptic action, without a noticeable cataleptic action occurring.
Patent HU-T70449-A (HU)
Title: Highly concentrated immunoglobulin preparation and method for its production
Inventor: EIBL JOHANN
IPC: A61K39/395
Filed: 1994-12-27
Abstract: A stable, highly concentrated immunoglobulin preparation which is intravenously tolerated and has an immunoglobulin content of 13.5 to 17.5 % (W/V), an osmolarity of 250 to 600 mOs/l and a viscosity not exceeding 9 Cp is described. The immunoglobulin preparation has excellent stability and can, because of its low viscosity even as highly concentrated preparation, be used intravenously without problems.
Patent HU-T75079-A (HU)
Inventor: PALKOVICS LAJOSNE
IPC: B65D85/72
Filed: 1995-04-19
Abstract: A találmányunk szerinti tárolóeszköz^ zárófedéllel /10/ és belső tároló térrel /4/, valamint melegítő térrel /5/ van ellátva, mely utóbbi túl hütött k r i s tá 3 yo 1 vadékkζ; 1 . például nátrium acetát trihidráttal van töltve, és e melegítő térhez /5/ egy kristályosodást beindító szerkezet /8/ van csatlakoztatva .
Patent HU-T73136-A (HU)
Title: Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceutical agents
Inventor: KJELL DOUGLAS PATTON
IPC: C07C217/54
Filed: 1995-08-30
Abstract: The present invention provides a novel process for preparing a compound of formula I <CHEM>  wherein     R is C1-C4 alkyl; R<1> and R<2> each are independently C1-C4 alkyl, or combine to form piperidinyl, pyrrolidinyl, methylpyrrolidino, dimethylpyrrolidino, morpholino, dimethylamino, diethylamino, or 1-hexamethyleneimino; and     n is 2 or 3;  or a pharmaceutically acceptable salt thereof, comprising   a) condensing (C1-C4 alkyl) 4-hydroxybenzoate with ethylene carbonate or propylene carbonate in the presence of a condensation catalyst and a moderately polar, water immiscible solvent having a high boiling point;   b) reacting the product of step a), a compound of formula III <CHEM>  wherein     R and n are as defined above, with a leaving group donor; and   c) reacting the product of step b), a compound of formula IV <CHEM>  wherein     R and n are as defined above and X is a leaving group, with a base selected from the group consisting of piperidine, pyrrolidine, methylpyrrolidine, dimethylpyrrolidine, morpholine, dimethylamine, diethylamine, and 1-hexamethyleneimine.   The product of the above process, a compound of formula I, also is novel and is useful for the preparation of pharmaceutically active compounds of formula II, particularly via the following novel process   <CHEM>  wherein     R is C1-C4 alkyl; R<1> and R<2> each are independently C1-C4 alkyl, or combine to form piperidinyl, pyrrolidinyl, methylpyrrolidino, dimethylpyrrolidino, morpholino, dimethylamino, diethylamino, or 1-hexamethyleneimino; and     n is 2 or 3;  or a pharmaceutically acceptable salt thereof, comprising   a) condensing (C1-C4 alkyl) 4-hydroxybenzoate with ethylene carbonate or propylene carbonate in the presence of a condensation catalyst and a moderately polar, water immiscible solvent having a high boiling point;   b) reacting the product of step a), a compound of formula III <CHEM>  wherein     R and n are as defined above, with a leaving group donor;   c) reacting the product of step b), a compound of formula IV <CHEM>  wherein     R and n are as defined above; and X is a leaving group, with a base selected from the group consisting of piperidine, pyrrolidine, methylpyrrolidine, dimethylpyrrolidine, morpholine, dimethylamine, diethylamine, and 1-hexamethyleneimine;   d) reacting the product of step c) with a compound of formula IV <MATH> wherein R<3> and R<4> are as defined above, or a pharmaceutically acceptable salt thereof;   e) optionally removing the reaction product from step d) ; and f) optionally forming a salt of the reaction product from either step d) or step e).
Patent HU-T76979-A (HU)
Title: Retroviral protease inhibitor combinations
Inventor: BRYANT MARTIN L
IPC: A61K31/357
Filed: 1995-06-02
Abstract: The present invention is directed to a method for selecting a first and a second retroviral protease inhibitor for administration to a patient, the method comprising 
(a) exposing said first retroviral protease inhibitor to a propagating culture of retroviruses and 
(b) determining the retroviral inhibitory activity of one or more candidate retroviral protease inhibitors against a retroviral strain that emerges after step (a), 
wherein said second retroviral protease inhibitor is selected from said candidate retroviral protease inhibitors based on its effectiveness against said retroviral strain.
Patent IL-41228-A (IL)
Title: Method of forming fins on tubes of difficult-to-roll meta
IPC: B21C37/20
Filed: 1973-01-03
Abstract: Rolling of high-fin integral finned tube from stainless steel or other difficult to form material, in two operations with an annealing step between rolling operations. Each rolling operation quickly forms narrow helical grooves to displace metal into wide helical ribs or rib portions, followed by more gradual widening and deepening of the grooves with additional metal displacement, and lateral application of pressure to the ribs to form it to required fin shape.
[US3795125A]
Patent IL-42906-A (IL)
Title: Touch actuated electronic switch
IPC: H03K17/96
Filed: 1973-08-03
Abstract: 1432453 Touch switches MAGIC DOT Inc 13 Aug 1973 [28 Aug 1972] 38226/73 Heading G1N The touch plate is connected to the input 52 of an A.C. energized amplifier 12 and normally floats at about ten volts (and power frequency) above earth ground. When touched the body capacity charging currents cause an output signal which is rectified at 45 to charge a storage (smoothing) capacitor at the input of a switching amplifier 30. A transistor amplifier and switching circuit is illustrated in Fig. 4 (not shown). In the first stage amplifier 12 the emitter is connected by a resistor to the base input circuit to provide the floating voltage. The amplifier 30 may include an F.E.T. input (not shown). The power supply transformer may be replaced by a potential divider Fig. 3 (not shown).
[GB1432453A]
Patent IL-74643-A (IL)
Title: Substituted phenylacetic acid iodopropargyl esters,their manufacture and their use as biocidal agents
IPC: A01N37/10
Filed: 1985-03-19
Abstract: 1. Claims for the Contracting States : BE, CH, DE, FR, GB, IT, LI, NL, SE Compounds of the general formula  see diagramm : EP0160962,P9,F3  whereby R signifies hydrogen, fluorine, chlorine, bromine, iodine, methoxy, 1-imidazolyl and 1,2,4-triazolyl, X stands for one or more identical or different substituents with the meaning fluorine, chlorine, bromine, iodine, cyano, nitro, carboxyl, alkyl with 1 to 12 carbon atoms, alkoxy with 1 to 12 carbon atoms, cycloalkyl with 3 to 6 carbon atoms, formyl, acetyl, propionyl, benzoyl, phenylsulphonyl, phenyl, phenoxy and substituted phenyl and phenoxy with, in each case, 1 to 3 substituents from the group fluorine, chlorine, bromine, nitro, methyl and methoxy, n is a whole number from 1 to 5 and, with the proviso that R does not signify hydrogen, can be 0. 1. Claims for the Contracting State : AT Process for the preparation of compounds of the general formula  see diagramm : EP0160962,P10,F2  whereby R signifies hydrogen, fluorine, chlorine, bromine, iodine, methoxy, 1-imidazolyl and 1,2,4-triazolyl, X stands for one or more identical or different substituents with the meaning fluorine, chlorine, bromine, iodine, cyano, nitro, carboxyl, alkyl with 1 to 12 carbon atoms, alkoxy with 1 to 12 carbon atoms, cycloalkyl with 3 to 6 carbon atoms, formyl, acetyl, propionyl, benzoyl, phenylsulphonyl, phenyl, phenoxy and substituted phenyl and phenoxy with, in each case, 1 to 3 substituents from the group fluorine, chlorine, bromine, nitro, methyl and methoxy, n a whole number of 1 to 5 and, with the proviso that R does not signify hydrogen, can be 0, characterised in that compounds of the formula see diagramm : EP0160962,P10,F3  whereby R, X and n possess the above meaning and A stands for chlorine, bromine, iodine, acyloxy and alkoxycarbonyloxy, are reacted with 3-iodopropynol in the presence of an acid-binding agent.
Patent IL-87883-A (IL)
Title: Preparation of an expandable vinyl plastisol
IPC: C08L27/06
Filed: 1988-09-29
Abstract: Process for the preparation of an expandable vinyl plastisol capable of yielding cellular products containing a nitrogen-based blowing agent and a zinc salt as accelerator of decomposition of the blowing agent. The accelerator, which is preferably zinc chloride, is incorporated in the plastisol in the form of a solution in a liquid carrier. The process results in cellular products consisting of uniform fine cells without any major change in color.
Patent JP-S58129293-A (JP)
Inventor: YOSHIMOTO YUUICHIROU
IPC: G21C17/02
Filed: 1982-01-27
Abstract: (57)【要約】本公報は電子出願前の出願データであるた め要約のデータは記録されません。
Patent JP-S62169420-A (JP)
Title: Method and apparatus for surface treatment
Inventor: MIZOGAMI KAZUAKI
IPC: H01L21/304
Filed: 1986-01-22
Abstract: PURPOSE:To prevent a material to be treated from having traces of water drops after it is dried, by freezing any liquid on the material and causing the freezed liquid to sublime for removing the liquid. CONSTITUTION:A casette 20 containing a semiconductor wafer 19 which has been treated by a chemical liquid and then washed roughly is disposed in a predetermined section within a water washing tank 12. A valve 18 is opened to introduce pure water into the water washing tank 12, and the semiconductor wafer 19 is washed finally while the water is caused to overflow. The pure water within the tank 12 is then removed completely. After that, a valve 7 is opened to introduce vapor of IPA isopropyl alcohol 8 into a body container 1 whereby the IPA is condensed on the surface of the semiconductor wafer 19. The valve 7 is then closed. A cooling gas is introduced into the water washing tank 12 so that mixture liquid present on the semiconductor wafer 19 is freezed. After all the valves are once closed, the valve 11 is opened to produce a vacuum within the body container 1. The freezed liquid is thereby accelerated to sublime and the semiconductor wafer 19 is dried.
Patent JP-S54103956-A (JP)
Title: Device for operating gear transmission
Inventor: YAO MAMORU
IPC: F16H63/30
Filed: 1978-01-31
Abstract: PURPOSE: To prevent selecting operation and shifting operation from becoming impossible due to lost gearing, by blocking one shifting rail from sliding in the axial direction when anothr shifting rail is selected.  
     CONSTITUTION: A projection 16, which receives the selecting motion of a control lever 1 to rotate a shifting rail 6 for high and low speeds, is provided on the shifting rail 6. Recesses 17,18, 19, 20, locking balls 23, 24 which are pushed in by springs 21, 22, and an interlocking pin 25 which is moved back or forth by the sliding or rotation of the shifting rail 6 or another shifting rail 5 for driving of two or four wheels and then fitted in one of the recesses 18, 19 of the shifting rails 5, 6 are provided at supported parts of the shifting rails. When one shifting rail is rotated, the interlocking pin 25 is fitted in the recess of the other shifting rail to prevent it from sliding in the axial direction. 
     COPYRIGHT: (C)1979,JPO&Japio
Patent JP-H04245436-A (JP)
Title: Manufacture of bump electrode for integrated circuit device use
Inventor: SHIRAHATA HISASHI
IPC: H01L21/60
Filed: 1991-01-31
Abstract: PURPOSE:To automatically detect a defective bump electrode which can be produced at a flip chip on an integrated circuit device without relying on the human effort of a visual inspection or the like. CONSTITUTION:A lower-side substratum film 5 and an upper-side substratum film 6 are applied to the whole surface so as to be connected to an interconnection film 3 exposed in a window part 4a in an insulating film 4 which covers the surface of a wafer on which an integrated circuit has been formed; the upper-side substratum film 6 is etched in such a way that a part used to form a bump electrode 10 is left; the upper-side substratum film 6 is plated preliminarily with a metal 7 for bump electrode use; the metal is etched partially; in addition, it is plated electrolytically with a metal for bump electrode use so as to be in a desired thickness; the bump electrode 10 is formed; the lower-side substratum film 5 excluding the lower part of the bump electrode is etched and removed.
Patent JP-S55104449-A (JP)
Title: High-strength high-electrically-conductive copper alloy with superior weldability
Inventor: MORI SHIGENOBU
IPC: C22C9/06
Filed: 1979-02-02
Abstract: PURPOSE: To enhance the weldability of a high-strength high-electrically-conductive copper alloy used as a material for the damper shield, etc. of a large capacity superconductive generator by adding a specified amt. of Ni and Si to copper.  
     CONSTITUTION: An alloy consisting of Ni 1.3W2.5wt%, Si 0.3W0.6wt%, and the balance Cu and inevitable impurities. The Ni and Si contents of the alloy is appropriately adjusted to a ratio in which a Ni 5 , Si 2  intermetallic cpd. is formed. The Ni and Si are mostly being dissolved in the copper before welding, and the Ni-Si intermetallic cpd. precipitates in an about equilibrium state at a desired temp. after welding. Accordingly, occurrence of weld cracks is prevented, and satisfactory welding results are obtd. by putting a Ni alloy on a groove even in welding to an iron alloy. By making use of this alloy no weld crack occurs in a damper shield, etc., and superior strength and electrical conductivity are provided. 
     COPYRIGHT: (C)1980,JPO&Japio
Patent JP-S56107667-A (JP)
Title: Time service system
Inventor: TAKIGUCHI MASAHISA
IPC: H04M3/42
Filed: 1980-01-31
Abstract: PURPOSE:To enable to know the present time in the area concerned at the time when dialing has been made, by storing the list showing the difference in time corresponding to the area code of each area, and displaying the difference in time or the time of transmitting destination, which has been calculated from said difference in time, on the calling telephone set side. CONSTITUTION:The timer 23C in the control circuit 23 generates a pulse at every constant interval, and gives an interruption to the CPU23A. The CPU23A sets the Japanese standard time by counting the interrupted pulses, and writes it in the prescribed memory area in the memory circuit 23B. When the Japanese standard time which has been read out in this case is made ''T'', the CPU23A executes the operation of ''T-C'' (provided that C shows the difference in time). The circuit 23 sends out the data showing said time X1, X2, Y1, Y2 to the data highway 21 through the interface circuit 22 from the I/O circuit 23D. Said data are amplified by the amplifier, and after that, they are sent out to the data line 101 through the hybrid transformer. The conversion code is provided to the indicator 2C1 through other I/O circuit.
Patent JP-H04330526-A (JP)
Title: Relocatable assembler
Inventor: KURAHASHI KEIICHI
IPC: G06F9/45
Filed: 1991-01-31
Abstract: PURPOSE:To optimize a branch instruction over the range of homonymous segments divided in the same source program file. CONSTITUTION:A source program file 11 is read out in a step 101, and when a line analyzing result is a branch instruction, the processing for setting up the information of the branch instruction in a branch instruction information table 14 and storing each segment in a memory is continuously executed until the end of the file 11. In the optimizing processing of a step 103 to be executed after the end of the file 11, an optimum branch instruction is selected from the table 14 in each segment, determined and stored in a memory as a branch instruction determining table 15. In the object forming processing of a step 104, the branch instruction determined by the table 15 is finally outputted to an object module file 12.
Patent JP-S61171949-A (JP)
Title: Differential planetary roller speed reducer
Inventor: KANEHISA YASUNORI
IPC: F16H13/08
Filed: 1985-01-23
Abstract: PURPOSE:To increase pressure contacting force while reduce slippage and increase the efficiency of torque transmission by forming a planetary roller with a material having greater linear expansion coefficient than that of an output ring. CONSTITUTION:A planetary roller 3 in which large diameter part and a small diameter part are provided, is formed by a material having a greater linear expansion coefficient than that of a first output ring 4 and a second output ring 5. Due to this construction, when high load is applied to the output rings 4, 5, slippage occurs between the planetary roller 3 and an input shaft 1 or the output rings 4, 5, causing the planetary roller to expand due to the resultant heat generation. Thereupon, the pressure contacting force between the planetary roller 3 and the input shaft 1 and output rollers 4, 5 is increased, increasing the efficiency of torque transmission.
Patent JP-H09205752-A (JP)
Title: Motor cover fitting device
Inventor: KAYAHARA YUKIO
IPC: H02K5/15
Filed: 1996-01-25
Abstract: PROBLEM TO BE SOLVED: To improve the workability of motor cover fitting work so as to reduce the assembling man-hour of a motor and to reduce the cost of members by providing hollow spacers which become the guides of through bolts which are screwed in the bolt holes of a frame and cylindrical sections which are put in the through holes of the cover for preventing the tilting of the spacers. SOLUTION: Mounting bolt holes 1a are provided into the rear end face of a motor frame 1. A cover 3 having cylindrical sections 3a supports hollow spacers 2 with the cylindrical sections 3a. The spacers 2 are passed through the cylindrical sections 3a of the cover 3 with narrow gaps in between. The frame 1 and cover 3 are joined together through a faucet joint and tightly united in one body with through bolts which are passed through the hollow sections of the spacers 2 and equipped with flat washers. Since the cylindrical sections 3a provided in the through holes of the cover 3 guide the spacers 2 to prescribed positions and, at the same time, prevent the tilting of the spacers 2, the bolts 4 can be easily screwed in the bolt holes 1a of the frame 1 from the outside of the cover 3.
Patent JP-2000204579-A (JP)
Title: Hook mounting structure of crane specification type back-hoe
Inventor: YABE KAZUO
IPC: E02F3/36
Filed: 1999-01-19
Abstract: PROBLEM TO BE SOLVED: To eliminate the mounting of a hook whenever crane work is carried out, on the contrary, eliminate the removal of the hook whenever excavation work is carried out, eliminate troublesome detachable work befor the work and to promote work efficiency by only operation to lock with the other end of the hook and to release the locking. SOLUTION: One end of the hook is pivoted on a pivot 23 connecting a bucket 12 and an arm 11, and the other end of the hook is locked with a stay 18 connecting the bucket and a piston rod 15a of a cylinder to make it possible to store the hook. The hook is constituted of a mounting base section 64, a joint section 65 and an interlock section 66, they are respectively connected with a first pivoting pin 78 and a second pivoting pin 79, a first pivoting pin mounting hole is opened in the mounting base section, a pair of right and left strays are arranged in parallel, a stored interlocking pin is projected to the inside surface side of the stay on one side, and the front end of the hook is locked with the stored locking pin to bend it to store.
Patent JP-H09201637-A (JP)
Title: Manufacture of one side flangeless wheel rim and device therefor
Inventor: TAKANO SADAYUKI
IPC: B21H1/04
Filed: 1996-01-25
Abstract: PROBLEM TO BE SOLVED: To improve the yield of a material and obviate the need of cutting off processing by expanding one end of an annular rim blank, rounded a rim blank and weld-joined and successively, forming into the rim shape with plural steps of roll formings. SOLUTION: The necessary size of rim material is rounded and the butted ends are weld-joined to form the annular rim blank 11. The end part 16 at a flangeless side of the annular rim blank 11 remains as almost straight-state and a flaring work for expanding only the end part 17 at the reverse side is applied. The end part 16 at the almost straight side of the annular rim blank 11 is formed as the rim-shape with plural steps of roll-formings while butting to a butting ring 18 in the rim axial direction. Successively, the end part 16 at the flangeless side is sized by cutting and a valve piercing is executed and successively, the rim end part 16 is turning-worked. The end part 17 at the flaring side is rolling-formed to form the flange part 13. By this method, the trouble of scrap treatment is saved and one side flangeless wheel rim can be manufactured.
Patent JP-S54103525-A (JP)
Title: Electrical route insulation resistance supervising device
Inventor: TATEMURA NOBUO
IPC: G01R27/18
Filed: 1978-02-02
Abstract: PURPOSE: To make able to perform testing correctly of an amplifier, a comparator, a time limitting circuit, a switching circuit and a reset circuit by making to detect a signal from a detecting resistor constituting so as test resistances to be in parallel with a real electrical route.  
     CONSTITUTION: When pressing a test button 23, a current supplied by a direct current power source 20 flows to a test resistor 24 through a current limitting resistor 14 and a detecting resistor 6 and a closed circuit to return to the direct current  power source 20 is established. At this time a signal is generated at both ends of the  detecting resist 6 by a current flowing through the detecting resistor and causes to  simulate an exactly similar phenomenon as that of an insulation deterioration of  either one of electrical routes 1 - 3. Accordingly by determining a resistance value  of the test resistor 24 in accordance with a supervising insulation resistance value a  state near to areal failure can be achieved and can withness normal operations of  an amplifier 71, a comparator 72, a time limitting circuit 73, a switching circuit 74  and of a reset circuit 25. 
     COPYRIGHT: (C)1979,JPO&Japio